ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags25o10 |
|---|---|
| Clone Library Name | barley_pub |
>FKB70_ARATH (Q38931) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Peptidylprolyl isomerase ROF1) Length = 551 Score = 301 bits (771), Expect = 9e-82 Identities = 140/192 (72%), Positives = 171/192 (89%), Gaps = 1/192 (0%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCPA 184 DICKDG +FKKILA GEKWENPKD DEV VK+EA+LEDGT+V KSDGVEFTVK+GHFCPA Sbjct: 149 DICKDGGVFKKILAVGEKWENPKDLDEVLVKFEAKLEDGTVVGKSDGVEFTVKDGHFCPA 208 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIG 364 ++KA+KTMKK EK LLTVKPQYGFG +G+PAS GE AVPPNA L+I+L+LVSWKTV+E+ Sbjct: 209 LTKAVKTMKKGEKVLLTVKPQYGFGEKGKPASAGEGAVPPNATLEINLELVSWKTVSEVT 268 Query: 365 NDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGH-DGEEPFEFKTDEDQV 541 +D ++KK+L+EG+GY+RP + + VKVKLIGKL DGT+F+KKGH + EEPFEFKTDE+QV Sbjct: 269 DDNKVVKKVLKEGDGYERPNEGAVVKVKLIGKLQDGTVFLKKGHGENEEPFEFKTDEEQV 328 Query: 542 IDGLDKAVLSMK 577 +DGLD+AV+ MK Sbjct: 329 VDGLDRAVMKMK 340 Score = 113 bits (282), Expect = 4e-25 Identities = 72/186 (38%), Positives = 97/186 (52%), Gaps = 4/186 (2%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAI 199 KK+L EGE +E P++ DEV V Y L DGT S +FT+ +G I Sbjct: 42 KKLLKEGEGYETPENGDEVEVHYTGTLLDGTKFDSSRDRATPFKFTLGQGQVIKGWDIGI 101 Query: 200 KTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTI 379 KTMKK E A+ T+ + +G G P + +P NA LQ D++L+ W +V +I D + Sbjct: 102 KTMKKGENAVFTIPAELAYGESGSPPT-----IPANATLQFDVELLKWDSVKDICKDGGV 156 Query: 380 LKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDK 559 KKIL GE ++ PKD V VK KL+DGT+ K DG EF + L K Sbjct: 157 FKKILAVGEKWENPKDLDEVLVKFEAKLEDGTVVGKS--DG---VEFTVKDGHFCPALTK 211 Query: 560 AVLSMK 577 AV +MK Sbjct: 212 AVKTMK 217 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/131 (32%), Positives = 64/131 (48%), Gaps = 13/131 (9%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS------DGVEFTVKE 166 ++ D + KK+L EG+ +E P + V VK +L+DGT+ K + EF E Sbjct: 266 EVTDDNKVVKKVLKEGDGYERPNEGAVVKVKLIGKLQDGTVFLKKGHGENEEPFEFKTDE 325 Query: 167 GHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNA-------MLQID 325 + +A+ MKK E AL+T+ P+Y FG + + A VPPN+ +L D Sbjct: 326 EQVVDGLDRAVMKMKKGEVALVTIDPEYAFG--SNESQQELAVVPPNSTVTYEVDLLTFD 383 Query: 326 LQLVSWKTVTE 358 + SW TE Sbjct: 384 KERESWDMNTE 394
>FKB70_WHEAT (Q43207) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 559 Score = 296 bits (757), Expect = 4e-80 Identities = 141/191 (73%), Positives = 165/191 (86%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCPA 184 DI KDG IFKKIL EG+KWENPKD DEVFVKYEARLEDGT+V+KS+GVEFTVK+GH CPA Sbjct: 152 DIAKDGGIFKKILKEGDKWENPKDPDEVFVKYEARLEDGTVVSKSEGVEFTVKDGHLCPA 211 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIG 364 ++KA+KTMKK EK LL VKPQYGFG GRPA+ AVPPNA L IDL+LVSWKTVTEIG Sbjct: 212 LAKAVKTMKKGEKVLLAVKPQYGFGEMGRPAAGEGGAVPPNASLVIDLELVSWKTVTEIG 271 Query: 365 NDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVI 544 +DK ILKK+L+E EGY+RP + + V VK+ GKL DGT+F+KKGHD +EPFEFKTDE+ VI Sbjct: 272 DDKKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQEPFEFKTDEEAVI 331 Query: 545 DGLDKAVLSMK 577 +GLD+AVL+MK Sbjct: 332 EGLDRAVLNMK 342 Score = 122 bits (306), Expect = 7e-28 Identities = 76/195 (38%), Positives = 105/195 (53%), Gaps = 4/195 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGH 172 +I K G + KK+L EGE W+ P+ DEV V Y L DG S D +F + +G Sbjct: 37 EIGKQG-LKKKLLKEGEGWDTPEVGDEVEVHYTGTLLDGKKFDSSRDRDDTFKFKLGQGQ 95 Query: 173 FCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTV 352 + IKTMKK E AL T+ P+ +G G P + +P NA LQ D++L+SW +V Sbjct: 96 VIKGWDQGIKTMKKGENALFTIPPELAYGESGSPPT-----IPANATLQFDVELLSWTSV 150 Query: 353 TEIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDE 532 +I D I KKIL+EG+ ++ PKD V VK +L+DGT+ K E EF + Sbjct: 151 RDIAKDGGIFKKILKEGDKWENPKDPDEVFVKYEARLEDGTVVSK-----SEGVEFTVKD 205 Query: 533 DQVIDGLDKAVLSMK 577 + L KAV +MK Sbjct: 206 GHLCPALAKAVKTMK 220 Score = 70.5 bits (171), Expect = 3e-12 Identities = 46/143 (32%), Positives = 74/143 (51%), Gaps = 8/143 (5%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS-----DGVEFTVKEG 169 +I D I KK+L E E +E P + V VK +L+DGT+ K + EF E Sbjct: 269 EIGDDKKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQEPFEFKTDEE 328 Query: 170 HFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSW-- 343 + +A+ MKK E AL+T+ P+Y +G S+ +A VPPN+ + +++LVS+ Sbjct: 329 AVIEGLDRAVLNMKKGEVALVTIPPEYAYGS---TESKQDAIVPPNSTVIYEVELVSFVK 385 Query: 344 -KTVTEIGNDKTILKKILQEGEG 409 K ++ N + I ++ EG Sbjct: 386 DKESWDLNNSEKIEAAGTKKEEG 408
>FKBP4_RABIT (P27124) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 457 Score = 84.7 bits (208), Expect = 2e-16 Identities = 64/197 (32%), Positives = 91/197 (46%), Gaps = 9/197 (4%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 +D + K I EG E P D VFV Y L DGT S D F + +G Sbjct: 28 QDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIK 87 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK--TVT 355 A A+ TMK E +T KP+Y +G G P +PPNA L +++L +K +T Sbjct: 88 AWDIAVATMKVGELCRITCKPEYAYGSAGSPPK-----IPPNATLVFEVELFEFKGEDLT 142 Query: 356 EIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDED 535 + D I+++I GEGY RP D + V+V L G D + F+ E Sbjct: 143 D-DEDGGIIRRIRTRGEGYARPNDGAIVEVALEGYYKDRLF-------DQRELRFEVGEG 194 Query: 536 QVID---GLDKAVLSMK 577 + +D GL+KA+ M+ Sbjct: 195 ESLDLPCGLEKAIQRME 211 Score = 52.4 bits (124), Expect = 9e-07 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 3/118 (2%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCP---A 184 +DG I ++I GE + P D V V E +D + + F V EG Sbjct: 145 EDGGIIRRIRTRGEGYARPNDGAIVEVALEGYYKDRLFDQRE--LRFEVGEGESLDLPCG 202 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTE 358 + KAI+ M+K E ++L +KP Y FG G+ + +PP A L+ ++ L S++ E Sbjct: 203 LEKAIQRMEKGEHSILYLKPSYAFGNAGKE----KFQIPPYAELKYEVHLKSFEKAKE 256
>FKB59_DROME (Q9VL78) FK506-binding protein 59 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (dFKBP59) Length = 439 Score = 82.8 bits (203), Expect = 6e-16 Identities = 59/196 (30%), Positives = 97/196 (49%), Gaps = 6/196 (3%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGT----LVTKSDGVEFTVKEGH 172 D+ DG + K+IL EG E P V + Y RL DGT +++++ EF++ +G+ Sbjct: 8 DLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEFDSSLSRNEPFEFSLGKGN 67 Query: 173 FCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTV 352 A + TMK E+ LT P Y +G G P A+PP+A L +L+++ WK Sbjct: 68 VIKAFDMGVATMKLGERCFLTCAPNYAYGAAGSP-----PAIPPDATLIFELEMLGWKGE 122 Query: 353 TEIGN-DKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTD 529 N D +I + IL+ + P D + VK + G +G +F D + F++ Sbjct: 123 DLSPNQDGSIDRTILEASDKKRTPSDGAFVKAHISGSF-EGRVF----EDRDVEFDYGEG 177 Query: 530 ED-QVIDGLDKAVLSM 574 + +IDG++ A+ M Sbjct: 178 KAIGIIDGVEIALEKM 193 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/74 (37%), Positives = 38/74 (51%) Frame = +2 Query: 356 EIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDED 535 ++ D +LK+IL+EG G + P TV + G+L DGT F EPFEF + Sbjct: 8 DLSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEF-DSSLSRNEPFEFSLGKG 66 Query: 536 QVIDGLDKAVLSMK 577 VI D V +MK Sbjct: 67 NVIKAFDMGVATMK 80
>FKBP4_MOUSE (P30416) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 457 Score = 81.3 bits (199), Expect = 2e-15 Identities = 64/197 (32%), Positives = 91/197 (46%), Gaps = 9/197 (4%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 +D + K I EG E P D VFV Y L DGT S D F + +G Sbjct: 28 QDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIK 87 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK--TVT 355 A A+ TMK E +T KP+Y +G G P +PPNA L +++L +K +T Sbjct: 88 AWDIAVATMKVGEVCHITCKPEYAYGAAGSPPK-----IPPNATLVFEVELFEFKGEDLT 142 Query: 356 EIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDED 535 E D I+++I GEGY RP D + V+V L G D + F+ E Sbjct: 143 E-EEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLF-------DQRELCFEVGEG 194 Query: 536 QVID---GLDKAVLSMK 577 + +D GL++A+ M+ Sbjct: 195 ESLDLPCGLEEAIQRME 211 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/118 (28%), Positives = 59/118 (50%), Gaps = 3/118 (2%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCP---A 184 +DG I ++I GE + P D V V E +D + + F V EG Sbjct: 145 EDGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLFDQRE--LCFEVGEGESLDLPCG 202 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTE 358 + +AI+ M+K E +++ +KP Y FG G+ + +PP+A L+ +++L S++ E Sbjct: 203 LEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQ----IPPHAELRYEVRLKSFEKAKE 256
>FKBP4_HUMAN (Q02790) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 458 Score = 80.5 bits (197), Expect = 3e-15 Identities = 66/197 (33%), Positives = 93/197 (47%), Gaps = 9/197 (4%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 +D + K I EG E P D VFV Y L DGT S D F + +G Sbjct: 28 QDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIK 87 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK--TVT 355 A AI TMK E +T KP+Y +G G P +PPNA L +++L +K +T Sbjct: 88 AWDIAIATMKVGEVCHITCKPEYAYGSAGSPPK-----IPPNATLVFEVELFEFKGEDLT 142 Query: 356 EIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDED 535 E D I+++I GEGY +P + + V+V L G D K D E F+ E Sbjct: 143 E-EEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD------KLFDQRE-LRFEIGEG 194 Query: 536 QVID---GLDKAVLSMK 577 + +D GL++A+ M+ Sbjct: 195 ENLDLPYGLERAIQRME 211 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 3/118 (2%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCP---A 184 +DG I ++I GE + P + V V E +D + + F + EG Sbjct: 145 EDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRE--LRFEIGEGENLDLPYG 202 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTE 358 + +AI+ M+K E +++ +KP Y FG G+ + +PPNA L+ +L L S++ E Sbjct: 203 LERAIQRMEKGEHSIVYLKPSYAFGSVGKE----KFQIPPNAELKYELHLKSFEKAKE 256
>FKBP5_MOUSE (Q64378) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) Length = 456 Score = 76.6 bits (187), Expect = 5e-14 Identities = 57/199 (28%), Positives = 91/199 (45%), Gaps = 11/199 (5%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVE----FTVKEGHFCP 181 KD + K + G E P D+V+V Y+ L DG S + F++ +G Sbjct: 29 KDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIK 88 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 A + TMKK E L KP+Y +G G +P NA L +++L+ +K ++ Sbjct: 89 AWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQK-----IPSNATLFFEIELLDFKG-EDL 142 Query: 362 GNDKTILKKILQEGEGYDRPKDCSTVKVKLIG-------KLDDGTMFVKKGHDGEEPFEF 520 D ++++I ++GEGY P + +TVKV L G D V +G D + P Sbjct: 143 FEDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPI-- 200 Query: 521 KTDEDQVIDGLDKAVLSMK 577 G+DKA++ M+ Sbjct: 201 ---------GIDKALVKMQ 210 Score = 54.3 bits (129), Expect = 2e-07 Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 3/121 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEG--HFC 178 D+ +D + ++I +GE + NP + V V E T + V F V EG H Sbjct: 141 DLFEDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRD--VVFVVGEGEDHDI 198 Query: 179 P-AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 P + KA+ M++ E+ +L + P+YGFG G+P + + PNA L ++ L S++ Sbjct: 199 PIGIDKALVKMQREEQCILYLGPRYGFGEAGKP----KFGIDPNAELMYEVTLKSFEKAK 254 Query: 356 E 358 E Sbjct: 255 E 255
>FKBP5_PONPY (Q5RF88) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 457 Score = 75.1 bits (183), Expect = 1e-13 Identities = 57/193 (29%), Positives = 94/193 (48%), Gaps = 5/193 (2%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 KD + K + G E P D+V+V Y+ +L +G S + F++ +G Sbjct: 29 KDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIK 88 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 A + TMKK E L KP+Y +G G +P NA L +++L+ +K ++ Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAG-----SLPKIPSNATLFFEIELLDFKG-EDL 142 Query: 362 GNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQV 541 D I+++ ++GEGY P + +TV++ L G+ G MF + + F ED V Sbjct: 143 FEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR----DVAFTVGEGEDHV 197 Query: 542 ID-GLDKAVLSMK 577 I G+DKA+ M+ Sbjct: 198 IPIGIDKALEKMQ 210 Score = 60.1 bits (144), Expect = 5e-09 Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 3/121 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEG--HFC 178 D+ +DG I ++ +GE + NP + V + E R G + V FTV EG H Sbjct: 141 DLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHVI 198 Query: 179 P-AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 P + KA++ M++ E+ +L + P+YGFG G+P + + PNA L ++ L S++ Sbjct: 199 PIGIDKALEKMQREEQCILYLGPRYGFGEAGKP----KFGIEPNAELIYEVTLKSFEKAK 254 Query: 356 E 358 E Sbjct: 255 E 255
>FKBP5_HUMAN (Q13451) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-bindin Length = 457 Score = 72.4 bits (176), Expect = 9e-13 Identities = 56/193 (29%), Positives = 93/193 (48%), Gaps = 5/193 (2%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 KD + K + G E P D+V+V Y+ +L +G S + F++ +G Sbjct: 29 KDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIK 88 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 A + TMKK E L KP+Y +G G +P NA L +++L+ +K ++ Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAG-----SLPKIPSNATLFFEIELLDFKG-EDL 142 Query: 362 GNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQV 541 D I+++ ++GEGY P + +TV++ L G+ G MF + + F ED Sbjct: 143 FEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR----DVAFTVGEGEDHD 197 Query: 542 ID-GLDKAVLSMK 577 I G+DKA+ M+ Sbjct: 198 IPIGIDKALEKMQ 210 Score = 59.3 bits (142), Expect = 8e-09 Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 3/121 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEG--HFC 178 D+ +DG I ++ +GE + NP + V + E R G + V FTV EG H Sbjct: 141 DLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHDI 198 Query: 179 P-AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 P + KA++ M++ E+ +L + P+YGFG G+P + + PNA L ++ L S++ Sbjct: 199 PIGIDKALEKMQREEQCILYLGPRYGFGEAGKP----KFGIEPNAELIYEVTLKSFEKAK 254 Query: 356 E 358 E Sbjct: 255 E 255
>FKBP5_CERAE (Q95L05) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 69.3 bits (168), Expect = 7e-12 Identities = 53/199 (26%), Positives = 90/199 (45%), Gaps = 11/199 (5%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 KD + K + G E P D+V+V Y+ +L +G S + F++ + Sbjct: 29 KDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFNSSHDRNEPFVFSLGKSQVIK 88 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 A + TMKK E L KP+Y +G G +P NA L +++L+ +K ++ Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAGSVPK-----IPSNATLFFEIELLDFKG-EDL 142 Query: 362 GNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLD-------DGTMFVKKGHDGEEPFEF 520 D I+++ ++GEGY P + +TV++ L G+ D V +G D + P Sbjct: 143 LEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGERMFDCRDVAFTVGEGEDHDIPI-- 200 Query: 521 KTDEDQVIDGLDKAVLSMK 577 G+DKA+ M+ Sbjct: 201 ---------GIDKALEKMQ 210 Score = 60.1 bits (144), Expect = 5e-09 Identities = 39/121 (32%), Positives = 64/121 (52%), Gaps = 3/121 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEG--HFC 178 D+ +DG I ++ +GE + NP + V + E R G + V FTV EG H Sbjct: 141 DLLEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC--GERMFDCRDVAFTVGEGEDHDI 198 Query: 179 P-AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 P + KA++ M++ E+ +L + P+YGFG G+P + + PNA L ++ L S++ Sbjct: 199 PIGIDKALEKMQREEQCILYLGPRYGFGEAGKP----KFGIEPNAELIYEVTLKSFEKAK 254 Query: 356 E 358 E Sbjct: 255 E 255
>FKBP5_SAGOE (Q9XSI2) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 68.9 bits (167), Expect = 1e-11 Identities = 53/199 (26%), Positives = 89/199 (44%), Gaps = 11/199 (5%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 KD + K + G E P D+V+V Y +L +G S + F++ +G Sbjct: 29 KDRGVLKIVKRVGHGEETPMIGDKVYVHYNGKLSNGKKFDSSHDRNEPFVFSIGKGQVIK 88 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 A + TMKK E L KP+Y +G G +P NA L +++L+++K ++ Sbjct: 89 AWDIGVSTMKKGEICHLLCKPEYAYGATG-----SLPKIPSNATLFFEVELLNFKG-EDL 142 Query: 362 GNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLD-------DGTMFVKKGHDGEEPFEF 520 D I+++ + GEGY P + + V++ L G+ D V +G D + P Sbjct: 143 LEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRCGGRVFDCRDVAFTVGEGEDHDIPI-- 200 Query: 521 KTDEDQVIDGLDKAVLSMK 577 G+DKA+ M+ Sbjct: 201 ---------GIDKALEKMQ 210 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 3/121 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEG--HFC 178 D+ +DG I ++ GE + NP + V + E R G V V FTV EG H Sbjct: 141 DLLEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRC--GGRVFDCRDVAFTVGEGEDHDI 198 Query: 179 P-AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 P + KA++ M++ E+ +L + P+YGFG G+P + + PNA L ++ L S++ Sbjct: 199 PIGIDKALEKMQREEQCILHLGPRYGFGEAGKP----KFGIEPNAELIYEVTLKSFEKAK 254 Query: 356 E 358 E Sbjct: 255 E 255
>PAS1_ARATH (Q7DMA9) Peptidyl-prolyl isomerase PASTICCINO1 (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 635 Score = 68.9 bits (167), Expect = 1e-11 Identities = 51/193 (26%), Positives = 89/193 (46%), Gaps = 8/193 (4%) Frame = +2 Query: 20 GSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLV--TKSDG------VEFTVKEGHF 175 GS+ K ++ G +P D D+V R DG +V T+S+ + + Sbjct: 32 GSLLKAVVRPGGGDSSPVDGDQVIYHCTVRTLDGVVVESTRSESGGRGVPIRDVLGNSKM 91 Query: 176 CPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 + + I TM K E A+ +KP+ + P S E P + L +++L+ + Sbjct: 92 ILGLLEGIPTMHKGEIAMFKMKPEMHYAEIDCPVSAPEN-FPKDDELHFEIELLDFSKAK 150 Query: 356 EIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDED 535 +D ++KKIL EGEG++ P++ VK ++ K DG + EEP+ F + Sbjct: 151 IASDDLGVIKKILNEGEGWESPREPYEVKARISAKSGDGHVIFS---HTEEPYFFTFGKS 207 Query: 536 QVIDGLDKAVLSM 574 +V GL+ + +M Sbjct: 208 EVPKGLEIGIGTM 220 Score = 60.1 bits (144), Expect = 5e-09 Identities = 53/198 (26%), Positives = 93/198 (46%), Gaps = 18/198 (9%) Frame = +2 Query: 17 DGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTK--SDGVEFTVKEGHFCPAVS 190 D + KKIL EGE WE+P++ EV + A+ DG ++ + FT + + Sbjct: 155 DLGVIKKILNEGEGWESPREPYEVKARISAKSGDGHVIFSHTEEPYFFTFGKSEVPKGLE 214 Query: 191 KAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQID---------LQLVSW 343 I TM + EKA++ V+ QY + + +L ID ++LV + Sbjct: 215 IGIGTMARKEKAVIYVRKQY---------------LTESPLLHIDQDLEEVHFEVELVHF 259 Query: 344 KTVTEIGNDKTILKKILQEGEGYDRPKDC----STVKVKLIGKL--DDGTMFV-KKGHDG 502 V ++ D ++K+ +++G G + P DC S + V G L ++ T+F K + Sbjct: 260 IQVRDMLGDGRLIKRRIRDGRG-EFPMDCPLQDSRLSVHYKGMLLNEEKTVFYDSKIDNN 318 Query: 503 EEPFEFKTDEDQVIDGLD 556 ++P EF + E V +G + Sbjct: 319 DQPLEFSSGEGLVPEGFE 336 Score = 29.6 bits (65), Expect = 6.5 Identities = 28/126 (22%), Positives = 49/126 (38%), Gaps = 11/126 (8%) Frame = +2 Query: 5 DICKDGSIFKKILAEGE---KWENPKDRDEVFVKYEARL--------EDGTLVTKSDGVE 151 D+ DG + K+ + +G + P + V Y+ L D + +E Sbjct: 264 DMLGDGRLIKRRIRDGRGEFPMDCPLQDSRLSVHYKGMLLNEEKTVFYDSKIDNNDQPLE 323 Query: 152 FTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQ 331 F+ EG + M E AL+T P Y + RP V A +Q +++ Sbjct: 324 FSSGEGLVPEGFEMCTRLMLPGEIALVTCPPDYAYDKFPRP-----PGVSEGAHVQWEIE 378 Query: 332 LVSWKT 349 L+ ++T Sbjct: 379 LLGFET 384
>FKBP5_AOTNA (Q9XT11) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 68.6 bits (166), Expect = 1e-11 Identities = 53/199 (26%), Positives = 88/199 (44%), Gaps = 11/199 (5%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 KD + K + G E P D+V+V Y +L +G S + F++ +G Sbjct: 29 KDRGVLKIVKRVGHGEETPMIGDKVYVHYNGKLSNGKKFDSSHDRNEPFVFSIGKGQVIK 88 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 A + TMKK E L KP+Y +G G +P NA L +++L+ +K ++ Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGATG-----SLPKIPSNATLFFEIELLDFKG-EDL 142 Query: 362 GNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLD-------DGTMFVKKGHDGEEPFEF 520 D I+++ + GEGY P + + V++ L G+ D V +G D + P Sbjct: 143 LEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRCGGRVFDCRDVAFTVGEGEDHDIPI-- 200 Query: 521 KTDEDQVIDGLDKAVLSMK 577 G+DKA+ M+ Sbjct: 201 ---------GIDKALEKMQ 210 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 3/121 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEG--HFC 178 D+ +DG I ++ GE + NP + V + E R G V V FTV EG H Sbjct: 141 DLLEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRC--GGRVFDCRDVAFTVGEGEDHDI 198 Query: 179 P-AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 P + KA++ M++ E+ +L + P+YGFG G+P + + PNA L ++ L S++ Sbjct: 199 PIGIDKALEKMQREEQCILHLGPRYGFGEAGKP----KFGIEPNAELIYEVTLKSFEKAK 254 Query: 356 E 358 E Sbjct: 255 E 255
>FKBP5_SAIBB (Q9XSH5) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 67.4 bits (163), Expect = 3e-11 Identities = 53/199 (26%), Positives = 87/199 (43%), Gaps = 11/199 (5%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCP 181 KD + K + G E P D V+V Y +L +G S + F++ +G Sbjct: 29 KDRGVLKIVKRVGHGEETPMIGDRVYVHYNGKLANGKKFDSSHDRNEPFVFSIGKGQVIK 88 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 A + TMKK E L KP+Y +G G +P NA L +++L+ +K ++ Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGATG-----SLPKIPSNATLFFEVELLDFKG-EDL 142 Query: 362 GNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLD-------DGTMFVKKGHDGEEPFEF 520 D I+++ + GEGY P + + V++ L G+ D V +G D + P Sbjct: 143 LEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRCGGRVFDCRDVAFTVGEGEDHDIPI-- 200 Query: 521 KTDEDQVIDGLDKAVLSMK 577 G+DKA+ M+ Sbjct: 201 ---------GIDKALEKMQ 210 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 3/121 (2%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEG--HFC 178 D+ +DG I ++ GE + NP + V + E R G V V FTV EG H Sbjct: 141 DLLEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRC--GGRVFDCRDVAFTVGEGEDHDI 198 Query: 179 P-AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVT 355 P + KA++ M++ E+ +L + P+YGFG G+P + + PNA L ++ L S++ Sbjct: 199 PIGIDKALEKMQREEQCILHLGPRYGFGEAGKP----KFGIEPNAELIYEVTLKSFEKAK 254 Query: 356 E 358 E Sbjct: 255 E 255
>FKBP3_HUMAN (Q00688) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 59.7 bits (143), Expect = 6e-09 Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 11/113 (9%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARLEDGTLVT-----------KSDGVEFTVKEGHFC 178 K +L +G+K PK D V Y L+DGT+ + + F V G Sbjct: 113 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVI 172 Query: 179 PAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 +A+ TM K EKA L ++P++ +G +G+P +A +PPNA L +++LV Sbjct: 173 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQP----DAKIPPNAKLTFEVELV 221 Score = 36.2 bits (82), Expect = 0.070 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 6/70 (8%) Frame = +2 Query: 383 KKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMF------VKKGHDGEEPFEFKTDEDQVI 544 K +L++G+ + PK V G L DGT+F K +P FK +VI Sbjct: 113 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVI 172 Query: 545 DGLDKAVLSM 574 G D+A+L+M Sbjct: 173 RGWDEALLTM 182
>FKBP3_RABIT (O46638) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) (Fragment) Length = 223 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 11/113 (9%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARLEDGTLVT-----------KSDGVEFTVKEGHFC 178 K +L +G+K PK D V Y L+DGT+ + + F V G Sbjct: 112 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVI 171 Query: 179 PAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 +A+ TM K EKA L ++P++ +G +G+P +A +PPNA L +++LV Sbjct: 172 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQP----DAKIPPNAKLIFEVELV 220 Score = 36.6 bits (83), Expect = 0.053 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 6/70 (8%) Frame = +2 Query: 383 KKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMF------VKKGHDGEEPFEFKTDEDQVI 544 K +L++G+ + PK V G L DGT+F K +P FK +VI Sbjct: 112 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVI 171 Query: 545 DGLDKAVLSM 574 G D+A+L+M Sbjct: 172 RGWDEALLTM 181
>FKBP3_BOVIN (P26884) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 58.5 bits (140), Expect = 1e-08 Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 11/113 (9%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARLEDGTLVT-----------KSDGVEFTVKEGHFC 178 K +L +G+K PK D V Y L+DGT+ + + F V G Sbjct: 113 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSFKVGIGKVI 172 Query: 179 PAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 +A+ TM K EKA L ++P++ +G +G+P +A +PPNA L +++LV Sbjct: 173 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQP----DAKIPPNAKLIFEVELV 221 Score = 36.2 bits (82), Expect = 0.070 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 6/70 (8%) Frame = +2 Query: 383 KKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMF------VKKGHDGEEPFEFKTDEDQVI 544 K +L++G+ + PK V G L DGT+F K +P FK +VI Sbjct: 113 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSFKVGIGKVI 172 Query: 545 DGLDKAVLSM 574 G D+A+L+M Sbjct: 173 RGWDEALLTM 182
>FKBP3_MOUSE (Q62446) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 56.6 bits (135), Expect = 5e-08 Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 11/113 (9%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARLEDGTLVT-----------KSDGVEFTVKEGHFC 178 K IL +G+K PK D V Y L DGT+ + + F V G Sbjct: 113 KSILKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVI 172 Query: 179 PAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 +A+ TM K EKA L ++P++ +G +G+P +A +PPN L +++LV Sbjct: 173 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQP----DAKIPPNTKLIFEVELV 221
>FKBP_SCHPO (O42993) FK506-binding protein (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) Length = 112 Score = 50.4 bits (119), Expect = 4e-06 Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARLEDG----TLVTKSDGVEFTVKEGHFCPAVSKAI 199 K++++ G + PK D + + Y L +G + V + T+ G + + Sbjct: 5 KQVISSGNGQDFPKPGDRITMHYTGTLTNGKKFDSSVDRGSPFVCTIGVGQLIRGWDEGV 64 Query: 200 KTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVS 340 M EKA LT+ P YG+G +G P +PPN+ L D++L++ Sbjct: 65 PKMSLGEKAKLTITPDYGYGPRGFP-----GLIPPNSTLLFDVELLA 106
>FKB1A_ASPFU (Q4WLV6) FK506-binding protein 1A (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 112 Score = 49.3 bits (116), Expect = 8e-06 Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 4/108 (3%) Frame = +2 Query: 26 IFKKILAEGEKWENPKDRDEVFVKYEARLEDGTL----VTKSDGVEFTVKEGHFCPAVSK 193 + K++ + G + PK D V + Y RL DG+ V +++ + + G + Sbjct: 3 VTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKFDSSVDRNEPFQTQIGTGRVIKGWDE 62 Query: 194 AIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 + M EKA+LT+ P YG+G +G P +P N+ L +++L+ Sbjct: 63 GVPQMSLGEKAVLTITPDYGYGARGFP-----PVIPGNSTLIFEVELL 105 Score = 38.1 bits (87), Expect = 0.018 Identities = 22/66 (33%), Positives = 32/66 (48%) Frame = +2 Query: 377 ILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLD 556 + K++ G G D PK V + G+L DG+ F D EPF+ + +VI G D Sbjct: 3 VTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKF-DSSVDRNEPFQTQIGTGRVIKGWD 61 Query: 557 KAVLSM 574 + V M Sbjct: 62 EGVPQM 67
>FKB12_DROME (P48375) 12 kDa FK506-binding protein (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Macrolide-binding protein) Length = 108 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/103 (27%), Positives = 48/103 (46%), Gaps = 4/103 (3%) Frame = +2 Query: 41 LAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTM 208 +A G+ PK+ +V V Y L+DGT S +FT+ +G + + + Sbjct: 8 IAPGDGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQL 67 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 ++A L P Y +G +G P +PPN+ L D++L+ Sbjct: 68 SVGQRAKLICSPDYAYGSRGHP-----GVIPPNSTLTFDVELL 105 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/58 (37%), Positives = 30/58 (51%) Frame = +2 Query: 401 GEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 G+G PK+ V V G LDDGT F D +PF+F + +VI G D+ V + Sbjct: 11 GDGSTYPKNGQKVTVHYTGTLDDGTKF-DSSRDRNKPFKFTIGKGEVIRGWDEGVAQL 67
>FKBP2_YARLI (Q6CGG3) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 144 Score = 48.1 bits (113), Expect = 2e-05 Identities = 37/109 (33%), Positives = 52/109 (47%), Gaps = 4/109 (3%) Frame = +2 Query: 26 IFKKILAEGEKWENPKDRDEVFVKYEARLEDGTL----VTKSDGVEFTVKEGHFCPAVSK 193 I KKI E E + + D V V Y +LEDGT+ V + ++F + G P + Sbjct: 32 ILKKISPE-ECTQKARKGDTVSVHYTGKLEDGTVFDSSVERGQPIQFPLGTGRVIPGWDQ 90 Query: 194 AIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVS 340 I M EK LT+ P +G QG A R +PP++ L +LVS Sbjct: 91 GILGMCVGEKRKLTIPPHLAYGKQG--AGR---VIPPDSTLIFTTELVS 134 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/66 (39%), Positives = 35/66 (53%) Frame = +2 Query: 377 ILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLD 556 ILKKI E E + + TV V GKL+DGT+F G +P +F +VI G D Sbjct: 32 ILKKISPE-ECTQKARKGDTVSVHYTGKLEDGTVFDSSVERG-QPIQFPLGTGRVIPGWD 89 Query: 557 KAVLSM 574 + +L M Sbjct: 90 QGILGM 95
>FKBP_KLULA (Q6CX30) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 45.1 bits (105), Expect = 1e-04 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 4/111 (3%) Frame = +2 Query: 17 DGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDG----TLVTKSDGVEFTVKEGHFCPA 184 +G++ L+ G+ PK D V + Y LE+G + V + + + G Sbjct: 6 EGNVQILRLSPGDSTNFPKPGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKG 65 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 AI + EKA LT+ Y +G +G P +PPNA L D++L+ Sbjct: 66 WDAAIPKLSVGEKARLTIPGPYAYGPRGFP-----GLIPPNATLVFDVELL 111
>FKBP_GIBZE (Q4HZB8) FK506-binding protein 1 (EC 5.2.1.8) (FKBP) (FkbA)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 111 Score = 45.1 bits (105), Expect = 1e-04 Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 11/112 (9%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARL--EDGTLVTKSDGVEFTVKEGHFCPAVS----- 190 K I+ +G +P+ +V ++Y L EDGT K D + +V G F + Sbjct: 5 KTIITQGSG-PSPQVGQKVTMEYTGWLQKEDGT---KGDQFDTSVGRGDFVVNIGVGQVI 60 Query: 191 ----KAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQL 334 + + MK EKA L + P YG+G +G P A+PPN+ L D++L Sbjct: 61 KGWDEGVTQMKLGEKATLHISPDYGYGPRGFP-----GAIPPNSTLIFDVEL 107
>FKBP8_HUMAN (Q14318) 38 kDa FK506-binding protein homolog (FKBPR38)| (FK506-binding protein 8) Length = 355 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 1/111 (0%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWEN-PKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCP 181 DI +G + KK L G + P V V + LE+GT V + + FT+ + Sbjct: 38 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQ 97 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQL 334 A+ ++ M E A++T +Y +G QGR +PP+A L +++ L Sbjct: 98 ALDLSVPLMDVGETAMVTADSKYCYGPQGR-----SPYIPPHAALCLEVTL 143
>FKBP_YARLI (Q6CF41) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 4/105 (3%) Frame = +2 Query: 35 KILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAVSKAIK 202 K L G+ PK D V + Y LE+G S + + T+ G + + Sbjct: 6 KQLQPGDGKTYPKKGDAVTIHYVGTLENGQKFDSSRDRGEPFKTTIGVGDVIRGWDEGVP 65 Query: 203 TMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 + E+++LT+ YG+G +G P +PPNA L D++L+ Sbjct: 66 KLSLGERSVLTISGDYGYGERGFP-----GLIPPNATLVFDVELL 105
>FKB10_MOUSE (Q61576) FK506-binding protein 10 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65) Length = 581 Score = 43.5 bits (101), Expect = 4e-04 Identities = 40/170 (23%), Positives = 70/170 (41%), Gaps = 11/170 (6%) Frame = +2 Query: 98 YEARLEDGTLVTKSDGVEFT----VKEGHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQ 265 Y L DGTL S T V +G+ P + + ++ E+ +TV P +G Sbjct: 292 YNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGACIGERRRITVPPHLAYGEN 351 Query: 266 GRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCST--- 436 G +P +A+L D+ ++ + ++ KT+ + P++C+ Sbjct: 352 GTGDK-----IPGSAVLIFDVHVIDFHNPSDPVEIKTLSRP----------PENCNETSK 396 Query: 437 ----VKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 ++ L DGT HD E P E ++VI+GLD+ + M Sbjct: 397 IGDFIRYHYNCSLLDGTRLFSS-HDYEAPQEITLGANKVIEGLDRGLQGM 445 Score = 33.5 bits (75), Expect = 0.45 Identities = 42/170 (24%), Positives = 65/170 (38%), Gaps = 5/170 (2%) Frame = +2 Query: 80 DEVFVKYEARLEDG----TLVTKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQ 247 D V Y EDG + +S V V G + + + M NE+ L V P Sbjct: 62 DFVRYHYNGTFEDGKKFDSSYDRSTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPH 121 Query: 248 YGFGGQGRPASRGEAAVPPNAMLQIDLQLVS-WKTVTEIGNDKTILKKILQEGEGYDRPK 424 G+G G +PP+A L D+ L+ W + TIL L+ + Sbjct: 122 LGYGSIG-----VAGLIPPDATLYFDVVLLDVWNKADTV--QSTIL---LRPPYCPRMVQ 171 Query: 425 DCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 + V+ G L DGT F + ++ +I G+D+ +L M Sbjct: 172 NSDFVRYHYNGTLLDGTGF-DNSYSRGGTYDTYIGSGWLIKGMDQGLLGM 220
>FKBP_CANGA (Q6FMA3) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 42.0 bits (97), Expect = 0.001 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 4/111 (3%) Frame = +2 Query: 17 DGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDG----TLVTKSDGVEFTVKEGHFCPA 184 +G + L+ G+ PK D V + Y LE+G + V + + + G Sbjct: 6 EGGVKIDRLSPGDGKTFPKQGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKG 65 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 I + EKA LT+ Y +G +G P +PPNA L D++L+ Sbjct: 66 WDAGIPKLSVGEKARLTIPGPYAYGPRGFP-----GLIPPNATLIFDVELL 111
>FKB22_ARATH (Q38936) FK506-binding protein 2-2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-2) Length = 163 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/58 (43%), Positives = 31/58 (53%), Gaps = 7/58 (12%) Frame = +2 Query: 416 RPKDCS-------TVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVL 568 +PK C T+KV GKL DGT+F G+ PFEFK QVI G D+ +L Sbjct: 41 KPKTCEVQAHKGDTIKVHYRGKLTDGTVFDSSFERGD-PFEFKLGSGQVIKGWDQGLL 97 Score = 36.2 bits (82), Expect = 0.070 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 4/91 (4%) Frame = +2 Query: 80 DEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQ 247 D + V Y +L DGT+ S D EF + G + + EK L + + Sbjct: 53 DTIKVHYRGKLTDGTVFDSSFERGDPFEFKLGSGQVIKGWDQGLLGACVGEKRKLKIPAK 112 Query: 248 YGFGGQGRPASRGEAAVPPNAMLQIDLQLVS 340 G+G QG P + +P A L D +L++ Sbjct: 113 LGYGEQGSPPT-----IPGGATLIFDTELIA 138
>FKB1A_BOVIN (P18203) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Frame = +2 Query: 41 LAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTM 208 ++ G+ PK V Y LEDG S +F + + + + M Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFVLGKQEVIRGWEEGVAQM 66 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 ++A LT+ P Y +G G P +PPNA L D++L+ Sbjct: 67 SVGQRAKLTISPDYAYGATGHP-----GIIPPNATLIFDVELL 104 Score = 34.7 bits (78), Expect = 0.20 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLS 571 + G+G PK T V G L+DG F D +PF+F + +VI G ++ V Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKF-DSSRDRNKPFKFVLGKQEVIRGWEEGVAQ 65 Query: 572 M 574 M Sbjct: 66 M 66
>FKBP8_MOUSE (O35465) 38 kDa FK506-binding protein homolog (FKBPR38)| (FK506-binding protein 8) (muFKBP38) Length = 355 Score = 40.8 bits (94), Expect = 0.003 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWEN-PKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCP 181 DI +G + K L K + P V V + LE+GT V + + FT+ + Sbjct: 38 DILGNGLLRMKTLVPCPKGSSRPLKGQVVTVHLQMSLENGTRVQEEPELAFTLGDCDVIQ 97 Query: 182 AVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQL 334 A+ ++ M E A++T +Y +G QGR +PP+A L +++ L Sbjct: 98 ALDLSVPLMDVGETAMVTADSKYCYGPQGR-----SPYIPPHAALCLEVTL 143
>FKBP_YEAST (P20081) FK506-binding protein 1 (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rapamycin-binding protein) Length = 114 Score = 40.0 bits (92), Expect = 0.005 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 4/111 (3%) Frame = +2 Query: 17 DGSIFKKILAEGEKWENPKDRDEVFVKYEARLEDG----TLVTKSDGVEFTVKEGHFCPA 184 +G++ ++ G+ PK D V + Y LE+G + V + + + G Sbjct: 6 EGNVKIDRISPGDGATFPKTGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKG 65 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 I + EKA LT+ Y +G +G P +PPN+ L D++L+ Sbjct: 66 WDVGIPKLSVGEKARLTIPGPYAYGPRGFP-----GLIPPNSTLVFDVELL 111
>FKB21_ARATH (Q38935) FK506-binding protein 2-1 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-1) Length = 153 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Frame = +2 Query: 80 DEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQ 247 D++ V Y +L DGT+ S D +EF + G P + + EK L + + Sbjct: 53 DKIKVHYRGKLTDGTVFDSSFERGDPIEFELGTGQVIPGWDQGLLGACVGEKRKLKIPSK 112 Query: 248 YGFGGQGRPASRGEAAVPPNAMLQIDLQLVS 340 G+G G P +P A L D +LV+ Sbjct: 113 LGYGDNGSPPK-----IPGGATLIFDTELVA 138 Score = 34.7 bits (78), Expect = 0.20 Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Frame = +2 Query: 392 LQEGEGYDRPKDCST-------VKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDG 550 LQ G Y +P+ C +KV GKL DGT+F G+ P EF+ QVI G Sbjct: 34 LQIGVKY-KPQKCDLQAHKGDKIKVHYRGKLTDGTVFDSSFERGD-PIEFELGTGQVIPG 91 Query: 551 LDKAVL 568 D+ +L Sbjct: 92 WDQGLL 97
>FKB1A_RAT (Q62658) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/103 (25%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Frame = +2 Query: 41 LAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTM 208 ++ G+ PK V Y LEDG S +FT+ + + + M Sbjct: 7 ISSGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQM 66 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 ++A L + P Y +G G P +PP+A L D++L+ Sbjct: 67 SVGQRAKLIISPDYAYGATGHP-----GIIPPHATLVFDVELL 104 Score = 35.4 bits (80), Expect = 0.12 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLS 571 + G+G PK T V G L+DG F D +PF+F + +VI G ++ V Sbjct: 7 ISSGDGRTFPKRGQTCVVHYTGMLEDGKKF-DSSRDRNKPFKFTLGKQEVIRGWEEGVAQ 65 Query: 572 M 574 M Sbjct: 66 M 66
>FKB1A_RABIT (P62943) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 39.3 bits (90), Expect = 0.008 Identities = 26/103 (25%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Frame = +2 Query: 41 LAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTM 208 ++ G+ PK V Y LEDG S +F + + + + M Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQM 66 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 ++A LT+ P Y +G G P +PP+A L D++L+ Sbjct: 67 SVGQRAKLTISPDYAYGATGHP-----GIIPPHATLVFDVELL 104 Score = 35.0 bits (79), Expect = 0.16 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLS 571 + G+G PK T V G L+DG F D +PF+F + +VI G ++ V Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKF-DSSRDRNKPFKFMLGKQEVIRGWEEGVAQ 65 Query: 572 M 574 M Sbjct: 66 M 66
>FKB1A_HUMAN (P62942) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 39.3 bits (90), Expect = 0.008 Identities = 26/103 (25%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Frame = +2 Query: 41 LAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTM 208 ++ G+ PK V Y LEDG S +F + + + + M Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQM 66 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 ++A LT+ P Y +G G P +PP+A L D++L+ Sbjct: 67 SVGQRAKLTISPDYAYGATGHP-----GIIPPHATLVFDVELL 104 Score = 35.0 bits (79), Expect = 0.16 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLS 571 + G+G PK T V G L+DG F D +PF+F + +VI G ++ V Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKF-DSSRDRNKPFKFMLGKQEVIRGWEEGVAQ 65 Query: 572 M 574 M Sbjct: 66 M 66
>FKB1A_EMENI (Q6KBA8) FK506-binding protein 1A (EC 5.2.1.8) (FKBP) (FkbA)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 39.3 bits (90), Expect = 0.008 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Frame = +2 Query: 41 LAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDGVEFT----VKEGHFCPAVSKAIKTM 208 ++ G+ PK D V + Y L DG+ S T + G + + + Sbjct: 8 ISPGDGKNFPKPGDTVSIHYTGTLADGSKFDSSRDRPGTFVTQIGVGRVIKGWDEGVLQL 67 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 EKA L P Y +G +G P +PPNA L +++L+ Sbjct: 68 SVGEKAKLICTPDYAYGARGFP-----PVIPPNATLTFEVELL 105 Score = 30.4 bits (67), Expect = 3.8 Identities = 19/61 (31%), Positives = 28/61 (45%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLS 571 + G+G + PK TV + G L DG+ F D F + +VI G D+ VL Sbjct: 8 ISPGDGKNFPKPGDTVSIHYTGTLADGSKF-DSSRDRPGTFVTQIGVGRVIKGWDEGVLQ 66 Query: 572 M 574 + Sbjct: 67 L 67
>FKBP_ASHGO (Q754K8) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 38.9 bits (89), Expect = 0.011 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 4/111 (3%) Frame = +2 Query: 17 DGSIFKKILAEGEKWENPKDRDEVFVKYEARLED----GTLVTKSDGVEFTVKEGHFCPA 184 +G++ L+ G+ PK D V + Y LE+ + V + + + G Sbjct: 6 EGNVKIDRLSPGDGKTFPKTGDLVTIHYTGTLENEQKFDSSVDRGSPFQCNIGVGQVIKG 65 Query: 185 VSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 AI + EKA LT+ Y +G +G P +PPNA L +++L+ Sbjct: 66 WDVAIPKLSVGEKARLTIPGAYAYGPRGFP-----GLIPPNATLIFEVELL 111
>MIP_COXBU (P51752) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Macrophage infectivity potentiator) Length = 230 Score = 38.5 bits (88), Expect = 0.014 Identities = 33/106 (31%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Frame = +2 Query: 35 KILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS--DGVEFTVKEGHFCPAVSKAIKTM 208 K+L G+ ++P DEV V YE RL +GT+ S G T +A+ M Sbjct: 129 KVLQAGQG-QSPTLNDEVTVNYEGRLINGTVFDSSYKRGQPATFPLKSVIKGWQEALTRM 187 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK 346 K + V PQ +G QG P + PN L + L+S K Sbjct: 188 KPGAIWEIYVPPQLAYGEQGAP-----GVIGPNEALIFKVNLISVK 228
>FKBP_DEBHA (Q6BX45) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 112 Score = 37.4 bits (85), Expect = 0.031 Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 4/106 (3%) Frame = +2 Query: 35 KILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAVSKAIK 202 +IL EG+ PK D V + Y LE+G S + T+ G I Sbjct: 10 EILQEGDGKTFPKPGDLVTIHYTGTLENGKKFDSSRDRGKPFQCTIGVGQVIVGWDTGIP 69 Query: 203 TMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVS 340 + +A L++ +G +G P +PPNA L D++L++ Sbjct: 70 KLSVGSRAKLSIPGHEAYGDRGFP-----GLIPPNATLLFDVELLN 110 Score = 34.7 bits (78), Expect = 0.20 Identities = 21/60 (35%), Positives = 29/60 (48%) Frame = +2 Query: 386 KILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAV 565 +ILQEG+G PK V + G L++G F D +PF+ QVI G D + Sbjct: 10 EILQEGDGKTFPKPGDLVTIHYTGTLENGKKF-DSSRDRGKPFQCTIGVGQVIVGWDTGI 68
>FKB10_HUMAN (Q96AY3) FK506-binding protein 10 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65) Length = 582 Score = 37.0 bits (84), Expect = 0.041 Identities = 37/171 (21%), Positives = 65/171 (38%), Gaps = 12/171 (7%) Frame = +2 Query: 98 YEARLEDGTLVTKSDGVEFT----VKEGHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQ 265 Y L DGTL S T + +G+ P + + ++ E+ +T+ P +G Sbjct: 293 YNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGEN 352 Query: 266 GRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCSTVKV 445 G +P +A+L ++ ++ + ++ +T+ RP + Sbjct: 353 GTGDK-----IPGSAVLIFNVHVIDFHNPADVVEIRTL-----------SRPSETCNETT 396 Query: 446 KLIG--------KLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 KL L DGT HD P E ++VI+GLD + M Sbjct: 397 KLGDFVRYHYNCSLLDGTQLFTS-HDYGAPQEATLGANKVIEGLDTGLQGM 446 Score = 36.6 bits (83), Expect = 0.053 Identities = 42/174 (24%), Positives = 66/174 (37%), Gaps = 9/174 (5%) Frame = +2 Query: 80 DEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQ 247 D V Y EDG S V V G + + + M NE+ L V P Sbjct: 63 DFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPH 122 Query: 248 YGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILK-----KILQEGEGY 412 G+G G +PP+A L D+ L+ + T+L+ +++Q+G+ Sbjct: 123 LGYGSIGL-----AGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGD-- 175 Query: 413 DRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 V+ G L DGT F G ++ +I G+D+ +L M Sbjct: 176 -------FVRYHYNGTLLDGTSFDTSYSKG-GTYDTYVGSGWLIKGMDQGLLGM 221
>FKB15_VICFA (Q41649) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15) Length = 151 Score = 37.0 bits (84), Expect = 0.041 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 4/90 (4%) Frame = +2 Query: 80 DEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQ 247 D+V V Y +L DGT+ S ++F + G + + M EK L + + Sbjct: 50 DKVKVHYRGKLTDGTVFDSSFERNSPIDFELGGGQVIKGWDQGLLGMCLGEKRKLKIPAK 109 Query: 248 YGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 G+G QG P + +P A L D +LV Sbjct: 110 LGYGEQGSPPT-----IPGGATLIFDTELV 134 Score = 34.7 bits (78), Expect = 0.20 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Frame = +2 Query: 392 LQEGEGYDRPKDCST-------VKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDG 550 LQ G Y +P C VKV GKL DGT+F + P +F+ QVI G Sbjct: 31 LQIGVKY-KPASCEVQAHKGDKVKVHYRGKLTDGTVF-DSSFERNSPIDFELGGGQVIKG 88 Query: 551 LDKAVLSM 574 D+ +L M Sbjct: 89 WDQGLLGM 96
>FKBP4_GIBZE (Q4INZ9) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 495 Score = 37.0 bits (84), Expect = 0.041 Identities = 24/53 (45%), Positives = 29/53 (54%), Gaps = 2/53 (3%) Frame = +2 Query: 422 KDCSTVKVKLIGKLDDGTMFV--KKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 K TV V+ IGKL +G F KKG +PF FK + QVI G D V+ M Sbjct: 407 KSGDTVGVRYIGKLQNGKQFDANKKG----KPFSFKAGKGQVIKGWDIGVIGM 455
>FKB1A_NEUCR (P20080) FK506-binding protein 1A (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) Length = 120 Score = 36.2 bits (82), Expect = 0.070 Identities = 22/64 (34%), Positives = 30/64 (46%) Frame = +2 Query: 386 KILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAV 565 ++ QEG+G + V V G L G F +D EP F + QVI G D+ + Sbjct: 12 EVQQEGQGTRETRRGDNVDVHYKGVLTSGKKF-DASYDRGEPLNFTVGQGQVIKGWDEGL 70 Query: 566 LSMK 577 L MK Sbjct: 71 LGMK 74 Score = 35.0 bits (79), Expect = 0.16 Identities = 28/110 (25%), Positives = 45/110 (40%), Gaps = 4/110 (3%) Frame = +2 Query: 35 KILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAVSKAIK 202 ++ EG+ + D V V Y+ L G S + + FTV +G + + Sbjct: 12 EVQQEGQGTRETRRGDNVDVHYKGVLTSGKKFDASYDRGEPLNFTVGQGQVIKGWDEGLL 71 Query: 203 TMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTV 352 MK EK LT+ P +G + +P N+ L + +LV K V Sbjct: 72 GMKIGEKRKLTIAPHLAYGNRA-----VGGIIPANSTLIFETELVGIKGV 116
>FKBP9_MOUSE (Q9Z247) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP65RS) Length = 570 Score = 36.2 bits (82), Expect = 0.070 Identities = 36/170 (21%), Positives = 69/170 (40%), Gaps = 11/170 (6%) Frame = +2 Query: 98 YEARLEDGTLVTKSDGVEFT----VKEGHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQ 265 Y L DGTL S T + +G+ P + + + + E+ + V P G+G + Sbjct: 285 YNGTLLDGTLFDSSYSRNHTFDTYIGQGYVIPGMDEGLLGVCIGERRRIVVPPHLGYGEK 344 Query: 266 GRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCST--- 436 GR ++P +A+L D+ ++ + ++ + + + +P DCS Sbjct: 345 GR------GSIPGSAVLVFDIHVIDFHNPSDSISITS-----------HYKPPDCSVLSK 387 Query: 437 ----VKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 +K L DGT+ + G + + QV+ G+D + M Sbjct: 388 KGDYLKYHYNASLLDGTLLDSTWNLG-KTYNIVLGSGQVVLGMDMGLREM 436
>FKB1A_MOUSE (P26883) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 36.2 bits (82), Expect = 0.070 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 4/103 (3%) Frame = +2 Query: 41 LAEGEKWENPKDRDEVFVKYEARLEDGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTM 208 ++ G+ PK V Y LEDG S +FT+ + + + M Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQM 66 Query: 209 KKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 ++A L + Y +G G P +PP+A L D++L+ Sbjct: 67 SVGQRAKLIISSDYAYGATGHP-----GIIPPHATLVFDVELL 104 Score = 35.0 bits (79), Expect = 0.16 Identities = 20/61 (32%), Positives = 29/61 (47%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLS 571 + G+G PK T V G L+DG F D +PF+F + +VI G ++ V Sbjct: 7 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKF-DSSRDRNKPFKFTLGKQEVIRGWEEGVAQ 65 Query: 572 M 574 M Sbjct: 66 M 66
>FKBP_NEIMA (P56989) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 35.8 bits (81), Expect = 0.091 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 4/110 (3%) Frame = +2 Query: 20 GSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAV 187 GS+ + L EG E K + E+ V Y LE+GT S + T+ G Sbjct: 2 GSLIIEDLQEGFGKEAVKGK-EITVHYTGWLENGTKFDSSLDRRQPLTITLGVGQVIKGW 60 Query: 188 SKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 + MK+ K LT+ + G+G +G +PP+A L +++L+ Sbjct: 61 DEGFGGMKEGGKRKLTIPSEMGYGARG-----AGGVIPPHATLIFEVELL 105
>FKBP4_ASPOR (Q2UN37) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 470 Score = 35.8 bits (81), Expect = 0.091 Identities = 22/50 (44%), Positives = 30/50 (60%), Gaps = 2/50 (4%) Frame = +2 Query: 431 STVKVKLIGKLDDGTMF--VKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 +TV ++ IGKL+DG +F KKG +PF FK + +VI G D V M Sbjct: 385 NTVAMRYIGKLEDGKVFDANKKG----KPFTFKLGKGEVIKGWDIGVAGM 430
>FKBP9_HUMAN (O95302) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 570 Score = 35.8 bits (81), Expect = 0.091 Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 11/170 (6%) Frame = +2 Query: 98 YEARLEDGTLVTKSDGVEFT----VKEGHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQ 265 Y L DGTL S T + +G+ P + + + + EK + V P G+G + Sbjct: 285 YNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEE 344 Query: 266 GRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCST--- 436 GR +P +A+L D+ ++ + ++ + + + +P DCS Sbjct: 345 GR------GNIPGSAVLVFDIHVIDFHNPSDSISITS-----------HYKPPDCSVLSK 387 Query: 437 ----VKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 +K L DGT+ + G + + QV+ G+D + M Sbjct: 388 KGDYLKYHYNASLLDGTLLDSTWNLG-KTYNIVLGSGQVVLGMDMGLREM 436
>FKBP6_MOUSE (Q91XW8) FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 35.4 bits (80), Expect = 0.12 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 6/119 (5%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWENPKDRDEVFVKYEARLE------DGTLVTKSDGVEFTVKE 166 DI D + K I+ EG D V VKY LE D K+ + + E Sbjct: 31 DISGDRGVLKDIIREGTGDTVTPDAS-VLVKYSGYLEHMDKPFDSNCFRKTPRL-MKLGE 88 Query: 167 GHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSW 343 + + +M+K E A KP Y +G G P +PPNA + +++L+ + Sbjct: 89 DITLWGMELGLLSMRKGELARFLFKPAYAYGTLGCP-----PLIPPNATVLFEIELIDF 142 Score = 30.4 bits (67), Expect = 3.8 Identities = 23/74 (31%), Positives = 35/74 (47%) Frame = +2 Query: 356 EIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDED 535 +I D+ +LK I++EG G D S V VK G L+ + P K ED Sbjct: 31 DISGDRGVLKDIIREGTGDTVTPDAS-VLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGED 89 Query: 536 QVIDGLDKAVLSMK 577 + G++ +LSM+ Sbjct: 90 ITLWGMELGLLSMR 103
>FKBP4_ASPFU (Q4WMV5) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 489 Score = 35.4 bits (80), Expect = 0.12 Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 2/50 (4%) Frame = +2 Query: 431 STVKVKLIGKLDDGTMF--VKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 +TV ++ IGKL+DG +F KKG +PF FK + +VI G D + M Sbjct: 404 NTVAMRYIGKLEDGKVFDANKKG----KPFTFKLGKGEVIKGWDIGIAGM 449
>FKBP9_RAT (Q66H94) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 570 Score = 35.4 bits (80), Expect = 0.12 Identities = 36/170 (21%), Positives = 69/170 (40%), Gaps = 11/170 (6%) Frame = +2 Query: 98 YEARLEDGTLVTKSDGVEFT----VKEGHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQ 265 Y L DGTL S T + +G+ P + + + + E+ + V P G+G + Sbjct: 285 YNGTLLDGTLFDSSYSRNHTFDTYIGQGYVIPGMDEGLLGVCIGERRRIVVPPHLGYGEE 344 Query: 266 GRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCST--- 436 GR ++P +A+L D+ ++ + ++ + + + +P DCS Sbjct: 345 GR------GSIPGSAVLVFDIHVIDFHNPSDSISITS-----------HYKPPDCSVLSK 387 Query: 437 ----VKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 +K L DGT+ + G + + QV+ G+D + M Sbjct: 388 KGDYLKYHYNASLLDGTLLDSTWNLG-KTYNIVLGFGQVVLGMDMGLREM 436
>FKB1B_EMENI (Q5AXD5) FK506-binding protein 1B (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 120 Score = 35.0 bits (79), Expect = 0.16 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 13/110 (11%) Frame = +2 Query: 26 IFKKILAEGEKWENPKDRDEVFVKYEARLED----------GTLVTKSDG---VEFTVKE 166 + K IL G ++P D V + Y L D GT S G ++ + Sbjct: 7 VTKTILRPGNGRDSPHTGDTVIIDYTGYLYDDTRGENEYFMGTQFDTSQGRGPLKTEIGV 66 Query: 167 GHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAML 316 G K ++ M EKA+LT+ G+G +G P +PP++ L Sbjct: 67 GKVILGWDKGVQQMTLGEKAILTISSDNGYGKRGFP-----GLIPPDSGL 111
>FKBP_NEIMC (P0A0W3) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 35.0 bits (79), Expect = 0.16 Identities = 30/110 (27%), Positives = 47/110 (42%), Gaps = 4/110 (3%) Frame = +2 Query: 20 GSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAV 187 GS+ + L E E K + E+ V Y LEDGT S + T+ G Sbjct: 2 GSLIIEDLQESFGKEAVKGK-EITVHYTGWLEDGTKFDSSLDRRQPLTITLGVGQVIKGW 60 Query: 188 SKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 + MK+ K LT+ + G+G G +PP+A L +++L+ Sbjct: 61 DEGFGGMKEGGKRKLTIPSEMGYGAHG-----AGGVIPPHATLIFEVELL 105
>FKBP_NEIMB (P0A0W2) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 33.9 bits (76), Expect = 0.35 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 4/110 (3%) Frame = +2 Query: 20 GSIFKKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS----DGVEFTVKEGHFCPAV 187 G + + L EG E K + E+ V Y LE+GT S + T+ G Sbjct: 2 GGLIIEDLQEGFGKEAVKGK-EITVHYTGWLENGTKFDSSLDRRQPLTITLGVGQVIKGW 60 Query: 188 SKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 + MK+ K LT+ + G+G G +PP+A L +++L+ Sbjct: 61 DEGFGGMKEGGKRKLTIPSEMGYGAHG-----AGGVIPPHATLIFEVELL 105
>FKBP2_ASPOR (Q2UPT7) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 134 Score = 33.9 bits (76), Expect = 0.35 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 5/91 (5%) Frame = +2 Query: 80 DEVFVKYEARLE-DGTLVTKS----DGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKP 244 D V + Y+ L+ DG+ S ++F V G + + M EK LT+ P Sbjct: 40 DTVQMHYKGTLQSDGSEFDSSYKRNSPLKFKVGSGMVIKGWDEGLLDMCIGEKRTLTIPP 99 Query: 245 QYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 +YG+G SRG +P A L + +LV Sbjct: 100 EYGYG------SRGVGPIPGGATLIFETELV 124
>FKBP2_HUMAN (P26885) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 142 Score = 33.9 bits (76), Expect = 0.35 Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Frame = +2 Query: 80 DEVFVKYEARLEDGT----LVTKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQ 247 D + + Y +LEDGT + ++ F++ G + + M + EK L + + Sbjct: 50 DVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSE 109 Query: 248 YGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 G+G +G P +P A L +++L+ + TE+ Sbjct: 110 LGYGERGAPPK-----IPGGATLVFEVELLKIERRTEL 142 Score = 30.4 bits (67), Expect = 3.8 Identities = 17/40 (42%), Positives = 21/40 (52%) Frame = +2 Query: 455 GKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 GKL+DGT F +PF F QVI G D+ +L M Sbjct: 58 GKLEDGTEF-DSSLPQNQPFVFSLGTGQVIKGWDQGLLGM 96
>FKBP3_CANAL (Q59VR3) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 426 Score = 33.5 bits (75), Expect = 0.45 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 3/95 (3%) Frame = +2 Query: 71 KDRDEVFVKYEARLEDGTLVTKS-DGVEFTVK--EGHFCPAVSKAIKTMKKNEKALLTVK 241 K +V ++Y +L++G + K+ G F+ K +G + M + + + Sbjct: 338 KSGAKVGIRYIGKLKNGKVFDKNTSGKPFSFKLGKGECIKGFDLGVTGMAVGGERRVIIP 397 Query: 242 PQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK 346 P+ G+G Q P +P N+ L D++LVS K Sbjct: 398 PKMGYGSQALPG------IPANSELTFDIKLVSLK 426 Score = 32.7 bits (73), Expect = 0.77 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Frame = +2 Query: 371 KTILKKILQE----GEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQ 538 KT+L ++ E G G K + V ++ IGKL +G +F K + +PF FK + + Sbjct: 318 KTLLGGVITEDRKIGSGATA-KSGAKVGIRYIGKLKNGKVFDK--NTSGKPFSFKLGKGE 374 Query: 539 VIDGLDKAVLSM 574 I G D V M Sbjct: 375 CIKGFDLGVTGM 386
>FKBP2_ASPFU (Q4WHX4) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 134 Score = 33.5 bits (75), Expect = 0.45 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 5/103 (4%) Frame = +2 Query: 80 DEVFVKYEARLE-DGTLVTKSDG----VEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKP 244 D V + Y L DG+ S G ++F + G + + M EK LT+ P Sbjct: 40 DTVHMHYRGTLAADGSEFDSSYGRNQPLKFKLGAGRVIKGWDEGLLDMCVGEKRTLTIPP 99 Query: 245 QYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDK 373 +YG+G RG +P A L + +LV + + ND+ Sbjct: 100 EYGYG------ERGIGPIPGGATLIFETELVQ---IEGVNNDE 133
>FKBP2_DEBHA (Q6BP84) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 135 Score = 33.5 bits (75), Expect = 0.45 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 4/93 (4%) Frame = +2 Query: 71 KDRDEVFVKYEARLEDGTL----VTKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTV 238 K D + V YE +LEDGT+ ++ + F + G + + M EK LT+ Sbjct: 38 KPGDLISVHYEGKLEDGTVFDSSYSRGQPISFQLGIGQVIQGWDQGLTRMCIGEKRKLTI 97 Query: 239 KPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 +G RG +P A L +LV Sbjct: 98 PSHLAYG------DRGVGPIPAKATLVFVAELV 124 Score = 30.4 bits (67), Expect = 3.8 Identities = 17/53 (32%), Positives = 26/53 (49%) Frame = +2 Query: 416 RPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 + K + V GKL+DGT+F + +P F+ QVI G D+ + M Sbjct: 36 KSKPGDLISVHYEGKLEDGTVF-DSSYSRGQPISFQLGIGQVIQGWDQGLTRM 87
>FKBP_METTL (O52980) FKBP-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (MtFK) Length = 154 Score = 33.1 bits (74), Expect = 0.59 Identities = 24/59 (40%), Positives = 31/59 (52%), Gaps = 12/59 (20%) Frame = +2 Query: 437 VKVKLIGKLDDGTMF------VKK-----GHDGE-EPFEFKTDEDQVIDGLDKAVLSMK 577 +KV IGKL+ G +F V K D E EP EF E Q+I G ++AVL M+ Sbjct: 11 IKVDYIGKLESGDVFDTSIEEVAKEAGIYAPDREYEPLEFVVGEGQLIQGFEEAVLDME 69
>FKBY_HAEIN (P44760) Probable FKBP-type peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 241 Score = 32.7 bits (73), Expect = 0.77 Identities = 25/67 (37%), Positives = 35/67 (52%) Frame = +2 Query: 377 ILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLD 556 ++ KI G+G D K TVKV GKL +G +F G +P EF+ DQVI G Sbjct: 134 LMYKIESAGKG-DTIKSTDTVKVHYTGKLPNGKVFDSSVERG-QPVEFQL--DQVIKGWT 189 Query: 557 KAVLSMK 577 + + +K Sbjct: 190 EGLQLVK 196
>FKB1B_NEUCR (Q6M981) FK506-binding protein 1B (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 110 Score = 32.3 bits (72), Expect = 1.0 Identities = 18/48 (37%), Positives = 25/48 (52%) Frame = +2 Query: 191 KAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQL 334 +A+ MK EKA L + YG+G +G +PPNA L D+ L Sbjct: 64 EAVLKMKVGEKATLDISSDYGYGERG-----FHGHIPPNADLIFDVYL 106
>FKBP2_MOUSE (P45878) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 140 Score = 32.3 bits (72), Expect = 1.0 Identities = 22/98 (22%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Frame = +2 Query: 80 DEVFVKYEARLEDGT----LVTKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQ 247 D + + Y +LEDGT + ++ F++ G + + M + EK L + + Sbjct: 48 DVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSE 107 Query: 248 YGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI 361 G+G +G P +P A L +++L+ + +E+ Sbjct: 108 LGYGERGAPPK-----IPGGATLVFEVELLKIERRSEL 140 Score = 30.4 bits (67), Expect = 3.8 Identities = 17/40 (42%), Positives = 21/40 (52%) Frame = +2 Query: 455 GKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 GKL+DGT F +PF F QVI G D+ +L M Sbjct: 56 GKLEDGTEF-DSSLPQNQPFVFSLGTGQVIKGWDQGLLGM 94
>FKB14_MOUSE (P59024) FK506-binding protein 14 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 211 Score = 32.3 bits (72), Expect = 1.0 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 7/96 (7%) Frame = +2 Query: 71 KDRDEVFVKYEARLE-DGTLV------TKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKAL 229 K D + V YE LE DG+L V FT+ + +K M EK Sbjct: 43 KGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPVWFTLGILEVLKGWDQGLKGMCVGEKRK 102 Query: 230 LTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 LTV P G+G +G+ +PP + L ++ L+ Sbjct: 103 LTVPPALGYGKEGK------GKIPPESTLIFNIDLL 132
>K0853_HUMAN (Q5T200) Protein KIAA0853| Length = 1668 Score = 32.3 bits (72), Expect = 1.0 Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 6/118 (5%) Frame = +2 Query: 62 ENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCPAV-----SKAIKTMKKNEKA 226 E PKD D +F L L+ K + G C A+ S K + KNEK Sbjct: 1554 EKPKDADNLFEHELGALNMAALLRKEERASLLSNLGPCCKALCFRRDSAIRKQLVKNEKG 1613 Query: 227 LLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEI-GNDKTILKKILQ 397 T+K Y A + N +L++ L+L KT G++KT K+ Q Sbjct: 1614 --TIKQAY-----------TSAPMVDNELLRLSLRLFKRKTTCHAPGHEKTEDNKLSQ 1658
>FKBP_ASPOR (Q2U316) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 116 Score = 32.0 bits (71), Expect = 1.3 Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 14/116 (12%) Frame = +2 Query: 32 KKILAEGEKWENPKDRDEVFVKYEARLEDGTLVTKS-DGVEF-------------TVKEG 169 +KI+ G +P D+V + Y + D K G +F + +G Sbjct: 5 RKIITRGSG-PSPASGDKVSIHYTGWIYDPKKANKGFQGKQFDSSRSPGRGPLVVNIGQG 63 Query: 170 HFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLV 337 + + M EK+ LT+ P YG+G + +P N+ L +++L+ Sbjct: 64 KVIKGWDEGVMQMSLGEKSTLTITPDYGYG------DKAAGKIPANSTLIFEVELL 113
>AGPA_RHIME (Q9X4Y1) Periplasmic alpha-galactoside-binding protein precursor| Length = 693 Score = 32.0 bits (71), Expect = 1.3 Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 38/167 (22%) Frame = +2 Query: 5 DICKDGSIFKKILAEGEKWEN--PKDRDEVFVKYEARLED----------------GTLV 130 D +DG L EG KW + P D D+V +E + D GT + Sbjct: 163 DWSEDGRKLTMHLIEGAKWSDGDPFDADDVMFYWEDNVLDSSVSPLNGATPETFGEGTTL 222 Query: 131 TKSDG--VEFTVKE------------GHFCPAVSKAIKTMKKNEKALLTVKPQY--GFGG 262 K D VE+T KE G FCP S +KT K+ K T +Y GF Sbjct: 223 KKIDQYTVEWTFKEAFPRQHLFAMAYGTFCPGPSHILKT--KHPKYAGTTYNEYKNGFPA 280 Query: 263 QGRPASRGEAAVP----PNAMLQIDLQLVSWKTVTEIGNDKTILKKI 391 + A VP P+ ++ + WK V E GN L ++ Sbjct: 281 EYMNLPVMGAWVPVAYRPDDIIVLRRNPYYWK-VDEAGNQLPYLNEL 326
>FKBP2_KLULA (Q6CUZ8) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 140 Score = 31.2 bits (69), Expect = 2.2 Identities = 19/59 (32%), Positives = 24/59 (40%), Gaps = 7/59 (11%) Frame = +2 Query: 419 PKDCS-------TVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 P DC V V GKL D ++ P +FK QVI G D+ +L M Sbjct: 33 PVDCKIKASKGDVVSVHYTGKLRDSGEIFDSSYNRGVPIQFKLGYSQVISGWDQGILGM 91
>FKBA_AERHY (O08437) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 268 Score = 31.2 bits (69), Expect = 2.2 Identities = 24/93 (25%), Positives = 38/93 (40%), Gaps = 2/93 (2%) Frame = +2 Query: 68 PKDRDEVFVKYEARLEDGTLVTKS--DGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVK 241 PK D V V Y L DGT S G T P ++ ++ M K + Sbjct: 169 PKATDIVKVHYTGTLTDGTKFDSSVDRGEPATFPLNQVIPGWTEGVQLMPVGSKFKFFLP 228 Query: 242 PQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVS 340 + +G G ++P NA+L D++L++ Sbjct: 229 SKLAYG------EHGAGSIPANAVLVFDVELLA 255
>HSP7F_SCHPO (O59838) Heat shock protein homolog pss1| Length = 720 Score = 31.2 bits (69), Expect = 2.2 Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 5/103 (4%) Frame = +2 Query: 14 KDGSIFKKILAEGEKWENPKDRDEVFVKYEARLED-----GTLVTKSDGVEFTVKEGHFC 178 ++ S FK++L + E W + D Y A+LED G + + E ++ Sbjct: 605 EESSKFKEMLTKAEDWLYEEGEDTTKAVYTAKLEDLMRVGGPIRQRYLDAEEAKRQKVQA 664 Query: 179 PAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPN 307 + T + EK + K + G GG+ P E P N Sbjct: 665 EREAAKAATKSEAEKQKPSGKFEEGTGGRAPPPPPAEEVAPEN 707
>FKBP6_HUMAN (O75344) FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 31.2 bits (69), Expect = 2.2 Identities = 21/74 (28%), Positives = 37/74 (50%) Frame = +2 Query: 356 EIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDED 535 +I D+ +LK +++EG G D ++V VK G L+ + + P K ED Sbjct: 31 DISGDRGVLKDVIREGAG-DLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGED 89 Query: 536 QVIDGLDKAVLSMK 577 + G++ +LSM+ Sbjct: 90 ITLWGMELGLLSMR 103
>MBB1A_MOUSE (Q7TPV4) Myb-binding protein 1A (Myb-binding protein of 160 kDa)| Length = 1344 Score = 31.2 bits (69), Expect = 2.2 Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 3/50 (6%) Frame = -3 Query: 153 NSTPSDFVTRVPSSSLASYLTKTSSR---SLGFSHFSPSASIFLNMLPSL 13 N DFVTRV S+SL S LTK +S + S FS I N+LP L Sbjct: 962 NCLDLDFVTRVYSASLESLLTKRNSSLTVPMFLSLFSRYPVICKNLLPVL 1011
>FKBP_CRYNE (Q5KMG3) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 30.8 bits (68), Expect = 2.9 Identities = 18/58 (31%), Positives = 28/58 (48%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAV 565 + G+G P+ +V + +G L DG+ F D PF + + QVI G D+ V Sbjct: 8 ISAGDGKTFPQPGDSVTIHYVGTLLDGSKF-DSSRDRGTPFVCRIGQGQVIRGWDEGV 64
>SLAPO_BREBE (P09333) Outer cell wall protein precursor (OWP)| Length = 1004 Score = 30.8 bits (68), Expect = 2.9 Identities = 15/42 (35%), Positives = 22/42 (52%) Frame = +2 Query: 341 WKTVTEIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIGKLD 466 +K V I ND K ++ G D P + VKVK +G++D Sbjct: 665 YKAVNSISNDVVENKSVITLTTGNDLPTTAAGVKVKTVGEVD 706
>FKBP_CRYNV (O94746) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 30.4 bits (67), Expect = 3.8 Identities = 18/58 (31%), Positives = 27/58 (46%) Frame = +2 Query: 392 LQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAV 565 + G+G P+ V + +G L DG+ F D PF + + QVI G D+ V Sbjct: 8 ISAGDGKTFPQPGDNVTIHYVGTLLDGSKF-DSSRDRGTPFVCRIGQGQVIRGWDEGV 64
>FKBP2_EMENI (Q5ATN7) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 135 Score = 30.4 bits (67), Expect = 3.8 Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Frame = +2 Query: 434 TVKVKLIGKL-DDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVLSM 574 TVK+ G L +DG+ F +D PF+FK +VI G D+ +L M Sbjct: 42 TVKMHYRGTLAEDGSQF-DASYDRGTPFKFKLGAGRVIKGWDEGLLDM 88 Score = 30.0 bits (66), Expect = 5.0 Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 6/88 (6%) Frame = +2 Query: 80 DEVFVKYEARL-EDGTLVTKS----DGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKP 244 D V + Y L EDG+ S +F + G + + M EK LT+ P Sbjct: 41 DTVKMHYRGTLAEDGSQFDASYDRGTPFKFKLGAGRVIKGWDEGLLDMCVGEKRTLTIPP 100 Query: 245 QYGFGGQG-RPASRGEAAVPPNAMLQID 325 +YG+G +G P G + +L+I+ Sbjct: 101 EYGYGDRGIGPIPGGATLIFQTELLEIE 128
>FKBP4_YEAST (Q06205) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 392 Score = 30.0 bits (66), Expect = 5.0 Identities = 23/100 (23%), Positives = 41/100 (41%), Gaps = 3/100 (3%) Frame = +2 Query: 56 KWENPKDRDEVFVKYEARLEDGTLV---TKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKA 226 K + K V ++Y +L++G + TK F + +G + M + Sbjct: 299 KGPHAKKGTRVGMRYVGKLKNGKVFDKNTKGKPFVFKLGQGEVIKGWDIGVAGMAVGGER 358 Query: 227 LLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK 346 + + Y +G Q P +P N+ L D++LVS K Sbjct: 359 RIVIPAPYAYGKQALPG------IPANSELTFDVKLVSMK 392
>MIP_LEGPN (P69059) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 233 Score = 30.0 bits (66), Expect = 5.0 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 2/95 (2%) Frame = +2 Query: 68 PKDRDEVFVKYEARLEDGTLV--TKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVK 241 P D V V+Y RL DGT+ T+ G T + P ++A++ M + V Sbjct: 141 PGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIPGWTEALQLMPAGSTWEIYVP 200 Query: 242 PQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK 346 +G P S G + PN L + L+S K Sbjct: 201 SGLAYG----PRSVG-GPIGPNETLIFKIHLISVK 230 Score = 29.3 bits (64), Expect = 8.5 Identities = 22/63 (34%), Positives = 32/63 (50%) Frame = +2 Query: 386 KILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAV 565 K++ G G +P TV V+ G+L DGT+F G +P F+ QVI G +A+ Sbjct: 131 KVINAGNGV-KPGKSDTVTVEYTGRLIDGTVFDSTEKTG-KPATFQV--SQVIPGWTEAL 186 Query: 566 LSM 574 M Sbjct: 187 QLM 189
>MIP_LEGPH (Q5ZXE0) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 233 Score = 30.0 bits (66), Expect = 5.0 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 2/95 (2%) Frame = +2 Query: 68 PKDRDEVFVKYEARLEDGTLV--TKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVK 241 P D V V+Y RL DGT+ T+ G T + P ++A++ M + V Sbjct: 141 PGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIPGWTEALQLMPAGSTWEIYVP 200 Query: 242 PQYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWK 346 +G P S G + PN L + L+S K Sbjct: 201 SGLAYG----PRSVG-GPIGPNETLIFKIHLISVK 230 Score = 29.6 bits (65), Expect = 6.5 Identities = 22/63 (34%), Positives = 32/63 (50%) Frame = +2 Query: 386 KILQEGEGYDRPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAV 565 K++ G G +P TV V+ G+L DGT+F G +P F+ QVI G +A+ Sbjct: 131 KVINSGNGV-KPGKSDTVTVEYTGRLIDGTVFDSTEKTG-KPATFQV--SQVIPGWTEAL 186 Query: 566 LSM 574 M Sbjct: 187 QLM 189
>FKBP2_GIBZE (Q4IN00) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 195 Score = 30.0 bits (66), Expect = 5.0 Identities = 29/147 (19%), Positives = 57/147 (38%), Gaps = 10/147 (6%) Frame = +2 Query: 80 DEVFVKYEARLEDG-----TLVTKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTVKP 244 D V + Y L+D + + F V G + + M EK +LT+ P Sbjct: 40 DGVHMHYRGTLKDSGKQFDASYDRGTPLSFKVGAGQVIKGWDEGLLDMCIGEKRVLTIPP 99 Query: 245 QYGFGGQGRPASRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEG----- 409 ++G+G R +P + L + +LV + + + I K+++ E Sbjct: 100 EFGYG------QRAIGPIPAGSTLVFETELVG---IDGVPKPEKIETKVVEGAESAAEAI 150 Query: 410 YDRPKDCSTVKVKLIGKLDDGTMFVKK 490 + + +T K+ GK+ + + K Sbjct: 151 SEATEAAATASQKVAGKVAEAIVDAAK 177
>Y2423_ARCFU (O30248) Hypothetical protein AF2423| Length = 209 Score = 30.0 bits (66), Expect = 5.0 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 6/40 (15%) Frame = -3 Query: 291 ASPLEAGLPCPPK------PYCGLTVRRAFSFFFIVLIAF 190 ASPL +P P + P GL VRR FSF++ ++ F Sbjct: 23 ASPLRYFIPYPAELLLFAIPLVGLAVRRPFSFYYYSVLIF 62
>MYSN_ACACA (P05659) Myosin-2 heavy chain, non muscle (Myosin II heavy chain,| non muscle) Length = 1509 Score = 30.0 bits (66), Expect = 5.0 Identities = 30/94 (31%), Positives = 34/94 (36%), Gaps = 2/94 (2%) Frame = +2 Query: 59 WENPKDRDEVFVKYEARLEDGTLVTKSDGVEFTVKEGHFCPAVSKAIKTMKKNEKALLTV 238 W KD D F E VTK DG FTV+ + K+ KNEK L V Sbjct: 38 WWPTKDADRAFCHVE--------VTKDDGKNFTVR------LENGEEKSQPKNEKNFLGV 83 Query: 239 KPQY--GFGGQGRPASRGEAAVPPNAMLQIDLQL 334 P G G E AV N + D L Sbjct: 84 NPPKFDGVEDMGELGYLNEPAVLHNLKKRYDADL 117
>TKT_STAAW (P66963) Transketolase (EC 2.2.1.1) (TK)| Length = 662 Score = 29.6 bits (65), Expect = 6.5 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Frame = +2 Query: 158 VKEGHFCPAVSKAIKTMKKNE-KALLTVKPQYGFGGQGRPASRGEAAVP 301 VK+G+ + KAI T K E ++ VK GFG + + G P Sbjct: 216 VKDGNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAP 264
>TKT_STAAS (Q6G9L6) Transketolase (EC 2.2.1.1) (TK)| Length = 662 Score = 29.6 bits (65), Expect = 6.5 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Frame = +2 Query: 158 VKEGHFCPAVSKAIKTMKKNE-KALLTVKPQYGFGGQGRPASRGEAAVP 301 VK+G+ + KAI T K E ++ VK GFG + + G P Sbjct: 216 VKDGNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAP 264
>TKT_STAAR (Q6GH64) Transketolase (EC 2.2.1.1) (TK)| Length = 662 Score = 29.6 bits (65), Expect = 6.5 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Frame = +2 Query: 158 VKEGHFCPAVSKAIKTMKKNE-KALLTVKPQYGFGGQGRPASRGEAAVP 301 VK+G+ + KAI T K E ++ VK GFG + + G P Sbjct: 216 VKDGNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAP 264
>TKT_STAAN (P99161) Transketolase (EC 2.2.1.1) (TK)| Length = 662 Score = 29.6 bits (65), Expect = 6.5 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Frame = +2 Query: 158 VKEGHFCPAVSKAIKTMKKNE-KALLTVKPQYGFGGQGRPASRGEAAVP 301 VK+G+ + KAI T K E ++ VK GFG + + G P Sbjct: 216 VKDGNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAP 264
>TKT_STAAM (P66962) Transketolase (EC 2.2.1.1) (TK)| Length = 662 Score = 29.6 bits (65), Expect = 6.5 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Frame = +2 Query: 158 VKEGHFCPAVSKAIKTMKKNE-KALLTVKPQYGFGGQGRPASRGEAAVP 301 VK+G+ + KAI T K E ++ VK GFG + + G P Sbjct: 216 VKDGNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAP 264
>TKT_STAAC (Q5HG77) Transketolase (EC 2.2.1.1)| Length = 662 Score = 29.6 bits (65), Expect = 6.5 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Frame = +2 Query: 158 VKEGHFCPAVSKAIKTMKKNE-KALLTVKPQYGFGGQGRPASRGEAAVP 301 VK+G+ + KAI T K E ++ VK GFG + + G P Sbjct: 216 VKDGNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAP 264
>SLYD_HELPY (O25748) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 185 Score = 29.6 bits (65), Expect = 6.5 Identities = 14/35 (40%), Positives = 21/35 (60%) Frame = +2 Query: 464 DDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKAVL 568 + G+ V + +EP EF +Q+I GL+KAVL Sbjct: 21 EQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVL 55
>FKBP2_CRYNE (Q5KGT9) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 141 Score = 29.6 bits (65), Expect = 6.5 Identities = 17/66 (25%), Positives = 30/66 (45%) Frame = +2 Query: 149 EFTVKEGHFCPAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPPNAMLQIDL 328 EFT+ G + + M +EK LT+ +G +G P +PP + L ++ Sbjct: 74 EFTLGAGQVIKGWDQGLLDMCISEKRKLTIPSHLAYGERGHP-----PVIPPQSTLVFEV 128 Query: 329 QLVSWK 346 +L+ K Sbjct: 129 ELLGIK 134
>NODD2_RHITR (P32008) Nodulation protein D 2| Length = 314 Score = 29.3 bits (64), Expect = 8.5 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Frame = +2 Query: 179 PAVSKAIKTMKKNEKALLTVKPQYGFGGQGRPASRGEAAVPP--NAMLQIDLQLVSWKTV 352 PA+S A+ ++ N + L G + P R E P +A+LQI L +VSW+ Sbjct: 35 PAMSAAVARLRTNFRDDLFAMA----GREFIPTPRAEGLAPAVRDALLQIQLSIVSWEPF 90 Query: 353 TEIGNDK 373 +D+ Sbjct: 91 NPAQSDR 97
>H11R_CHICK (P08288) Histone H1.11R| Length = 218 Score = 29.3 bits (64), Expect = 8.5 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 12/109 (11%) Frame = +2 Query: 272 PASRGEAAVPPNAMLQIDLQLVSWKTVTEI------------GNDKTILKKILQEGEGYD 415 PA++ A P A + + +VTE+ G LKK L G GYD Sbjct: 15 PAAKAAAKKPKKAAGGAKARKPAGPSVTELITKAVSASKERKGLSLAALKKALAAG-GYD 73 Query: 416 RPKDCSTVKVKLIGKLDDGTMFVKKGHDGEEPFEFKTDEDQVIDGLDKA 562 K+ S +K+ L + GT+ KG F +GL+KA Sbjct: 74 VEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFRLSKKPG---EGLEKA 119
>YNJ6_CAEEL (P34550) Hypothetical protein R10E11.6| Length = 349 Score = 29.3 bits (64), Expect = 8.5 Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 23/125 (18%) Frame = -3 Query: 312 IALGGTAASPLE-----------AGLPCPPKPYCGLTVRRAFS--------FFFIVLIAF 190 +A GGT+++ L +GLP + V RA F + LIA Sbjct: 56 VASGGTSSTALPNTGLVYNLMGTSGLPKDVLSHIWSAVNRAKPGQLTRPEFFSLLALIAL 115 Query: 189 DTAGQKCPSF-TVNSTPSDFVTRV---PSSSLASYLTKTSSRSLGFSHFSPSASIFLNML 22 G+ + ++S P ++ V P++S + T TSS + F PSA I ++L Sbjct: 116 AQKGESLAALCAMDSLPIPYLNPVQAFPTASNPAPTTNTSSSFVPFGKIKPSAFIPTSLL 175 Query: 21 PSLQM 7 P M Sbjct: 176 PRRSM 180
>LUKF_STAAU (P31715) Leukocidin F subunit precursor (Gamma-hemolysin, H-gamma-I| subunit) Length = 323 Score = 29.3 bits (64), Expect = 8.5 Identities = 18/70 (25%), Positives = 35/70 (50%) Frame = +2 Query: 278 SRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIG 457 + E + P ++ ++D ++ +KT +DK + +IL D+ D T+ +K G Sbjct: 24 ANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATG 83 Query: 458 KLDDGTMFVK 487 ++ G FVK Sbjct: 84 NINSG--FVK 91
>HLGB_STAAW (P0A076) Gamma-hemolysin component B precursor (H-gamma-1)| (H-gamma-I) Length = 325 Score = 29.3 bits (64), Expect = 8.5 Identities = 18/70 (25%), Positives = 35/70 (50%) Frame = +2 Query: 278 SRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIG 457 + E + P ++ ++D ++ +KT +DK + +IL D+ D T+ +K G Sbjct: 24 ANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATG 83 Query: 458 KLDDGTMFVK 487 ++ G FVK Sbjct: 84 NINSG--FVK 91
>HLGB_STAAU (P0A077) Gamma-hemolysin component B precursor (H-gamma-1)| (H-gamma-I) Length = 325 Score = 29.3 bits (64), Expect = 8.5 Identities = 18/70 (25%), Positives = 35/70 (50%) Frame = +2 Query: 278 SRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIG 457 + E + P ++ ++D ++ +KT +DK + +IL D+ D T+ +K G Sbjct: 24 ANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATG 83 Query: 458 KLDDGTMFVK 487 ++ G FVK Sbjct: 84 NINSG--FVK 91
>HLGB_STAAN (P0A075) Gamma-hemolysin component B precursor (H-gamma-1)| (H-gamma-I) Length = 325 Score = 29.3 bits (64), Expect = 8.5 Identities = 18/70 (25%), Positives = 35/70 (50%) Frame = +2 Query: 278 SRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIG 457 + E + P ++ ++D ++ +KT +DK + +IL D+ D T+ +K G Sbjct: 24 ANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATG 83 Query: 458 KLDDGTMFVK 487 ++ G FVK Sbjct: 84 NINSG--FVK 91
>HLGB_STAAC (Q5HDD3) Gamma-hemolysin component B precursor (H-gamma-1)| (H-gamma-I) Length = 325 Score = 29.3 bits (64), Expect = 8.5 Identities = 18/70 (25%), Positives = 35/70 (50%) Frame = +2 Query: 278 SRGEAAVPPNAMLQIDLQLVSWKTVTEIGNDKTILKKILQEGEGYDRPKDCSTVKVKLIG 457 + E + P ++ ++D ++ +KT +DK + +IL D+ D T+ +K G Sbjct: 24 ANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATG 83 Query: 458 KLDDGTMFVK 487 ++ G FVK Sbjct: 84 NINSG--FVK 91
>ENG1_YEAST (P53753) Endo-1,3(4)-beta-glucanase 1 precursor (EC 3.2.1.6)| (Endo-1,4-beta-glucanase 1) (Endo-1,3-beta-glucanase 1) (Laminarinase-1) (Daughter specific expression protein 4) Length = 1117 Score = 29.3 bits (64), Expect = 8.5 Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 3/152 (1%) Frame = -3 Query: 486 FTNMVPSSN---FPISFTLTVEQSLGRS*PSPSWRIFFRIVLSLPISVTVFQDTN*RSIC 316 F P+S+ +P + T + Q+L + SP++ R ++L SV+++ T+ Sbjct: 244 FIASTPASSTLFYPSNSTQDLVQTLASTTASPAYPSN-RTQITLSPSVSLYSTTSPIYPS 302 Query: 315 NIALGGTAASPLEAGLPCPPKPYCGLTVRRAFSFFFIVLIAFDTAGQKCPSFTVNSTPSD 136 NI G++ SP + P P S F V + + V+S+ Sbjct: 303 NITENGSSPSPSLSSTVSPVYPSSSTGNILLSSLFSTVDSSSSPVSSTLDTIYVSSSMQA 362 Query: 135 FVTRVPSSSLASYLTKTSSRSLGFSHFSPSAS 40 + SSS +S TKTSS SL S S + + Sbjct: 363 TI----SSSSSSRQTKTSSSSLSTSTSSTATT 390 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 81,215,426 Number of Sequences: 219361 Number of extensions: 1696343 Number of successful extensions: 5562 Number of sequences better than 10.0: 100 Number of HSP's better than 10.0 without gapping: 5223 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5487 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4929664480 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
