ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags26d07 |
|---|---|
| Clone Library Name | barley_pub |
>C71C4_MAIZE (Q43257) Cytochrome P450 71C4 (EC 1.14.-.-) (Benzoxazineless 2)| Length = 538 Score = 198 bits (504), Expect = 8e-51 Identities = 97/186 (52%), Positives = 132/186 (70%), Gaps = 2/186 (1%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALG--DDTDYIHDLLSIQ 177 FP L +++++R + C + RRV K WDDLL+ LI +H ++ A DD D+I+ LLS+Q Sbjct: 258 FPRLGRIELVRKVACAKTRRVRKRWDDLLDKLIDDHAARMATHQDEDDDKDFIYVLLSLQ 317 Query: 178 KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 KEY LTR+ +KA L+ MF AGTDTSY+ +E+AM L++ P LM KLQ EVR ++P G+ M Sbjct: 318 KEYGLTRDHIKAILIDMFEAGTDTSYMTLEFAMTELIRKPHLMKKLQEEVRRNVPAGQEM 377 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 V ED+L + LKAVIKETLRLH P PLL+PH ++ C + GYTIP+ TRV+VN+ A+ R Sbjct: 378 VTEDNLPGMTDLKAVIKETLRLHPPVPLLLPHYSLDACEVAGYTIPANTRVVVNAWALGR 437 Query: 538 DPSSWE 555 WE Sbjct: 438 HSGYWE 443
>C71C1_MAIZE (Q43250) Cytochrome P450 71C1 (EC 1.14.-.-) (Benzoxazineless 4)| Length = 535 Score = 186 bits (473), Expect = 3e-47 Identities = 91/188 (48%), Positives = 132/188 (70%), Gaps = 2/188 (1%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDT--DYIHDLLSIQ 177 FP+L +D+ ++C +A+ V+K WD L L+ E+ GD D++H LLS+Q Sbjct: 249 FPKLADVDLFLRIICAKAKSVSKRWDSLFNELLSEYALSGGKQ-GDHNSEDFVHLLLSLQ 307 Query: 178 KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 K+Y LT + +K LV MF A +TS++V+EY+M+ LM N ++ KLQ EVR++ P G+ M Sbjct: 308 KDYGLTTDNIKGILVNMFEAAIETSFLVLEYSMSELMNNRHVLAKLQKEVRTATPDGR-M 366 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 V+E+DL+ + YLKA IKE++R+H PAP L+PH + DC INGYTIP+GTRVIVN+ A+AR Sbjct: 367 VMEEDLSRMPYLKATIKESMRIHPPAPFLLPHFSTHDCEINGYTIPAGTRVIVNAWALAR 426 Query: 538 DPSSWESA 561 DP+ W+ A Sbjct: 427 DPTCWDKA 434
>C71C2_MAIZE (Q43255) Cytochrome P450 71C2 (EC 1.14.-.-) (Benzoxazineless 3)| Length = 536 Score = 176 bits (446), Expect = 4e-44 Identities = 92/189 (48%), Positives = 133/189 (70%), Gaps = 6/189 (3%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEH-ESKPAPALGD-DTDYIHDLLSIQK 180 P + D++ +V +ARR+N+ W+D+ + LI EH +S+P+ + + D+IH LLSIQ+ Sbjct: 254 PNMAMADVLLRLVSVKARRLNQRWNDVFDELIQEHVQSRPSGESEESEADFIHVLLSIQQ 313 Query: 181 EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSI--PKGKH 354 EY LT + +KA LV MF AG +TSY+ +EY MA L+ N +M KLQ EVR+++ P GK Sbjct: 314 EYGLTTDNLKAILVDMFEAGIETSYLTLEYGMAELINNRHVMEKLQTEVRTTMGSPDGKK 373 Query: 355 --MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRA 528 M+ E+DL + YLKA IKETLRLH PAP L+PH + AD I+GY +P+GTRV+V++ A Sbjct: 374 LDMLAEEDLGSMPYLKATIKETLRLHPPAPFLLPHYSTADSEIDGYFVPAGTRVLVHAWA 433 Query: 529 IARDPSSWE 555 + RD ++WE Sbjct: 434 LGRDRTTWE 442
>C71C3_MAIZE (P93703) Cytochrome P450 71C3 (EC 1.14.-.-) (Benzoxazineless 5)| Length = 535 Score = 155 bits (391), Expect = 1e-37 Identities = 86/181 (47%), Positives = 113/181 (62%), Gaps = 4/181 (2%) Frame = +1 Query: 25 DIIRWMVCGRARRVNKMWDDLLESLIHEH---ESKPAPALGDDTDYIHDLLSIQKEYNLT 195 D++ +VC + R K WD LLE +IHEH + D+I LS +EY T Sbjct: 257 DLLFRLVCWKVTRHLKRWDALLEEVIHEHVEMRKLSGDKEKESDDFIDIFLSRYEEYGFT 316 Query: 196 REQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS-SIPKGKHMVIEDD 372 + VK+ L+ +F A +TSY+V+E AMA LM + +M KLQAEVR+ K M+ EDD Sbjct: 317 MDNVKSLLMNVFEAAIETSYLVLESAMAELMNHRRVMKKLQAEVRAYGAEKKLDMIREDD 376 Query: 373 LNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 L+ L YLKA +KE LRLH P PLL+PH + ADC I+GY IP+ RV+VN AI RDP+ W Sbjct: 377 LSSLPYLKASMKEALRLHPPGPLLLPHYSTADCQIDGYHIPANPRVLVNGWAIGRDPAVW 436 Query: 553 E 555 E Sbjct: 437 E 437
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 145 bits (365), Expect = 1e-34 Identities = 73/172 (42%), Positives = 113/172 (65%), Gaps = 4/172 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQL 219 R R+ K D+ LE +IHE PA + +++ LL I + ++ R+ +KA + Sbjct: 245 RVDRIAKEMDEFLEKVIHERLENPAAKA--EENFVDILLEIYRNNSAGVSIDRDSIKAII 302 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + +F AGTDT+ +V+E+AM L+++P++M KLQ+EVR + K KH + +DD+ + YLKA Sbjct: 303 LDVFAAGTDTTAVVLEWAMTELLRHPEIMKKLQSEVRQVV-KDKHNITDDDIEKMHYLKA 361 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 V+KET+R H P PLLVP +A D + GY +P GT V++N+ AI RDP+SW+ Sbjct: 362 VMKETMRFHTPIPLLVPRVARNDVEVMGYDVPVGTMVMINAWAIGRDPTSWD 413
>C71A1_PERAE (P24465) Cytochrome P450 71A1 (EC 1.14.-.-) (CYPLXXIA1) (ARP-2)| Length = 471 Score = 135 bits (340), Expect = 8e-32 Identities = 84/194 (43%), Positives = 117/194 (60%), Gaps = 8/194 (4%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDD----TDYIHDLLS 171 FP +D++ M R +R + D ++ +I +H A G D D + LL Sbjct: 221 FPSFAWVDVLTGMDA-RLKRNHGELDAFVDHVIDDHLLS-RKANGSDGVEQKDLVDVLLH 278 Query: 172 IQKE----YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSI 339 +QK+ +L R +KA ++ MF GTDT+ + +E+AMA L+++PD+M K Q EVR + Sbjct: 279 LQKDSSLGVHLNRNNLKAVILDMFSGGTDTTAVTLEWAMAELIKHPDVMEKAQQEVRRVV 338 Query: 340 PKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVN 519 K K V E+DL+ L YLK +IKETLRLH APLLVP + D VI GY IP+ TRV +N Sbjct: 339 GK-KAKVEEEDLHQLHYLKLIIKETLRLHPVAPLLVPRESTRDVVIRGYHIPAKTRVFIN 397 Query: 520 SRAIARDPSSWESA 561 + AI RDP SWE+A Sbjct: 398 AWAIGRDPKSWENA 411
>C71AM_ARATH (Q9STL1) Cytochrome P450 71A22 (EC 1.14.-.-)| Length = 490 Score = 134 bits (336), Expect = 2e-31 Identities = 71/172 (41%), Positives = 108/172 (62%), Gaps = 4/172 (2%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQ 216 G+ ++ D+ LE ++ +HE A TD++ LL IQ+E + + R +KA Sbjct: 230 GQLKKTGNDLDEFLEKVVQDHEDGDAQR----TDFVDVLLRIQREKSVGFEIDRLSIKAI 285 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 ++ + GTDTSY +ME+AM L+ P+ + +LQ EVR+ I KG V EDD+ + YLK Sbjct: 286 ILDVVVGGTDTSYALMEWAMTELLHRPECLNRLQEEVRT-ICKGNSSVSEDDIKDMNYLK 344 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 AVIKET+RLH P PL+VPH + D + Y IP+GT+V++N+ AI R+ ++W Sbjct: 345 AVIKETMRLHPPLPLMVPHESTQDVRLGDYHIPAGTQVMINAWAIGREAATW 396
>C71DA_SOYBN (O48923) Cytochrome P450 71D10 (EC 1.14.-.-)| Length = 510 Score = 129 bits (324), Expect = 6e-30 Identities = 68/174 (39%), Positives = 112/174 (64%), Gaps = 6/174 (3%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSI------QKEYNLTREQVK 210 G+ +V+++ D +L+ +I EH+++ + ++ + + DL+ + + E+ LT + +K Sbjct: 246 GKLEKVHRVTDRVLQDIIDEHKNRNRSS--EEREAVEDLVDVLLKFQKESEFRLTDDNIK 303 Query: 211 AQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAY 390 A + +F G +TS V+E+ M+ L++NP +M + QAEVR + K V E +L+ L Y Sbjct: 304 AVIQDIFIGGGETSSSVVEWGMSELIRNPRVMEEAQAEVRR-VYDSKGYVDETELHQLIY 362 Query: 391 LKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 LK++IKET+RLH P PLLVP ++ C INGY IPS TR+I+N+ AI R+P W Sbjct: 363 LKSIIKETMRLHPPVPLLVPRVSRERCQINGYEIPSKTRIIINAWAIGRNPKYW 416
>F3PH_ARATH (Q9SD85) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (AtF3'H) (Cytochrome P450 75B1) (TRANSPARENT TESTA 7 protein) Length = 513 Score = 129 bits (324), Expect = 6e-30 Identities = 74/179 (41%), Positives = 108/179 (60%), Gaps = 9/179 (5%) Frame = +1 Query: 43 VCGRARRVNKMWDDLLESLIHEHESKPAPALGDD---TDYIHDLLSIQKEY------NLT 195 V G+ +R++K +D L S++ EHE G D TD + L+S++ +LT Sbjct: 234 VAGKMKRLHKRFDAFLSSILKEHEMN-----GQDQKHTDMLSTLISLKGTDLDGDGGSLT 288 Query: 196 REQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDL 375 ++KA L+ MF AGTDTS +++A+A L+++PD+M K Q E+ + + + V E D+ Sbjct: 289 DTEIKALLLNMFTAGTDTSASTVDWAIAELIRHPDIMVKAQEELDIVVGRDRP-VNESDI 347 Query: 376 NHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 L YL+AVIKE RLH P PL +PH+A C INGY IP G+ ++ N AIARDP W Sbjct: 348 AQLPYLQAVIKENFRLHPPTPLSLPHIASESCEINGYHIPKGSTLLTNIWAIARDPDQW 406
>C71A9_SOYBN (O81970) Cytochrome P450 71A9 (EC 1.14.-.-) (P450 CP1)| Length = 499 Score = 129 bits (323), Expect = 7e-30 Identities = 71/171 (41%), Positives = 109/171 (63%), Gaps = 4/171 (2%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN----LTREQVKAQLVI 225 R ++ +D +++ I ++ S+ + A + D + LL +QK+ N +T +Q+K LV Sbjct: 240 REMDNFYDQVIKEHIADNSSERSGA--EHEDVVDVLLRVQKDPNQAIAITDDQIKGVLVD 297 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +F AGTDT+ + + M+ L++NP M + Q EVR + GK MV E DL+ L Y+K+V+ Sbjct: 298 IFVAGTDTASATIIWIMSELIRNPKAMKRAQEEVRDLVT-GKEMVEEIDLSKLLYIKSVV 356 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 KE LRLH PAPLLVP +C I G+ IP+ TRV+VN+++IA DP WE+ Sbjct: 357 KEVLRLHPPAPLLVPREITENCTIKGFEIPAKTRVLVNAKSIAMDPCCWEN 407
>C71AL_ARATH (Q9STL2) Cytochrome P450 71A21 (EC 1.14.-.-)| Length = 490 Score = 129 bits (323), Expect = 7e-30 Identities = 68/172 (39%), Positives = 110/172 (63%), Gaps = 4/172 (2%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQ 216 G+ + D+ LE ++ +H G TD++ LL IQ+E + + R +KA Sbjct: 230 GQLNKTGNDLDEFLEKVVQDHVDGD----GQRTDFVDVLLRIQREKSIGFEIDRLCIKAI 285 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 ++ + AGTD+SY +M++AM L+++P+ + LQ EVR+ I KG V E+D+ +++YLK Sbjct: 286 VLDVLVAGTDSSYALMDWAMTELLRHPECLRTLQEEVRT-ICKGNLSVSEEDIQNMSYLK 344 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 AVIKET RLH P PLL PH ++ D ++ Y IP+GT+V++N+ AI R+ ++W Sbjct: 345 AVIKETTRLHPPLPLLAPHESIQDVILGDYHIPAGTQVMINAWAIGREAATW 396
>C71AN_ARATH (Q9STL0) Cytochrome P450 71A23 (EC 1.14.-.-)| Length = 483 Score = 127 bits (319), Expect = 2e-29 Identities = 70/171 (40%), Positives = 106/171 (61%), Gaps = 4/171 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQL 219 R + +D LLE ++ +HE GD TD++ LL+ Q++ +++ R +KA + Sbjct: 228 RLEKTANDFDKLLERIVQDHEDGD----GDKTDFVDVLLAAQRDKSFGFDIDRLSIKAIV 283 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + F GTDTS ++E+ M L+++P + KLQ EVR+ I KGK V EDD+ + YLKA Sbjct: 284 LDAFVGGTDTSSTLVEWEMTELLRHPTCLKKLQEEVRT-ICKGKSSVSEDDIQGMEYLKA 342 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 V+KE LRLH P PL+VPH + D + IP+GT+VIVN A+ R+ ++W Sbjct: 343 VVKEALRLHPPVPLMVPHQSTQDVRLRDNHIPAGTQVIVNLWAVGREAATW 393
>C71BV_ARATH (Q9LIP6) Cytochrome P450 71B34 (EC 1.14.-.-)| Length = 500 Score = 125 bits (315), Expect = 6e-29 Identities = 77/175 (44%), Positives = 101/175 (57%), Gaps = 6/175 (3%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEY------NLTREQVK 210 GR R + D E + H+ K D++ LL ++KE LTR +K Sbjct: 236 GRRERSMRDLDAFYEQMFDLHKQKKEEG---SEDFVDLLLRLEKEEAVLGNDKLTRNHIK 292 Query: 211 AQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAY 390 A L+ + AG DTS I M +AMA L +NP +M K+Q+E+RS I K K + DD + L Y Sbjct: 293 AILMDVLLAGMDTSAITMTWAMAELAKNPRVMKKVQSEIRSQI-KNKERISFDDTDKLEY 351 Query: 391 LKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LK VIKET RLH PLL+P AM++ INGYTIP TR+ VN AI RDP +W+ Sbjct: 352 LKMVIKETWRLHPTTPLLIPREAMSEFEINGYTIPVKTRLHVNVWAIGRDPDTWK 406
>C71AQ_ARATH (Q9STK7) Cytochrome P450 71A26 (EC 1.14.-.-)| Length = 489 Score = 125 bits (314), Expect = 8e-29 Identities = 71/186 (38%), Positives = 115/186 (61%), Gaps = 4/186 (2%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE- 183 P L +D IR + C + N + D E ++ +H D TD++ LL+IQ++ Sbjct: 216 PWLAWIDWIRGLDCQLEKTANDV-DKFFERVVQDH----VDGNRDMTDFVDVLLAIQRDK 270 Query: 184 ---YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 + + R +KA ++ +F GTDTS +ME+AM L+++P + +LQ EVR+ I K K Sbjct: 271 TVGFEINRVSIKAIVMNVFVGGTDTSSTLMEWAMTELLRHPKCLKRLQEEVRT-ICKDKS 329 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 V E+++ +++YLKAVIKE LRLH P PL+VPH + D + + IP+GT+V++N+ AI Sbjct: 330 SVSEEEIQNMSYLKAVIKEALRLHPPLPLMVPHESTQDVRLGDHHIPAGTQVLINAWAIG 389 Query: 535 RDPSSW 552 R+ ++W Sbjct: 390 REAATW 395
>C71AG_ARATH (Q9FH66) Cytochrome P450 71A16 (EC 1.14.-.-)| Length = 497 Score = 125 bits (314), Expect = 8e-29 Identities = 70/174 (40%), Positives = 105/174 (60%), Gaps = 4/174 (2%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN----LTREQVKAQ 216 G+ ++ K + D +E ++ EHE A + D++ LL+IQ++ L + +K Sbjct: 235 GKLEKITKQFGDFIEKVLQEHEDTTADK--ETPDFVDMLLTIQRDETAQCQLDKSDLKVI 292 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 + MF T T+ V+E+AM RLM+NP+ + KLQ E+RS + K V ++ ++ YLK Sbjct: 293 IFEMFLGSTTTTSAVIEWAMTRLMRNPECLKKLQDEIRS-VSKMNSYVSGKEVENMNYLK 351 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 AVIKE LRLH P PLLVP L D + GY I +GT+VI+N+ AI RD ++W S Sbjct: 352 AVIKEVLRLHPPLPLLVPRLLSEDVKLKGYDITAGTQVIINAWAIQRDTATWGS 405
>C71AC_ARATH (O49340) Cytochrome P450 71A12 (EC 1.14.-.-)| Length = 497 Score = 125 bits (314), Expect = 8e-29 Identities = 66/171 (38%), Positives = 103/171 (60%), Gaps = 4/171 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQL 219 R + V++ + DL++ ++ EH A D++ LLSI+ E + R+ +K + Sbjct: 237 RIKEVSQGFSDLMDKVVQEH----LEAGNHKEDFVDILLSIESEKSIGFQAQRDDIKFMI 292 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + MF GT TS ++E+ M L++NP++M KLQ E+RS+I + E D+ ++ YLKA Sbjct: 293 LDMFIGGTSTSSTLLEWIMTELIRNPNVMKKLQDEIRSTIRPHGSYIKEKDVENMKYLKA 352 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 VIKE R+H P PL++P L D + GY I +GT VI+N+ AI RDP+ W Sbjct: 353 VIKEVFRVHPPLPLILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDPAIW 403
>C71D9_SOYBN (O81971) Cytochrome P450 71D9 (EC 1.14.-.-) (P450 CP3)| Length = 496 Score = 125 bits (313), Expect = 1e-28 Identities = 69/172 (40%), Positives = 107/172 (62%), Gaps = 2/172 (1%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGD--DTDYIHDLLSIQKEYNLTREQVKAQLVI 225 + ++++ D +++++I+EH + A GD + + + D+L ++KE+ L+ E +KA + Sbjct: 236 KLEKLHQQADQIMQNIINEHREAKSSATGDQGEEEVLLDVL-LKKEFGLSDESIKAVIWD 294 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FG G+DTS + +AMA +++NP M K+Q EVR K + +L YLK+V+ Sbjct: 295 IFGGGSDTSSATITWAMAEMIKNPRTMEKVQTEVRRVFDK-EGRPNGSGTENLKYLKSVV 353 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWESA 561 ETLRLH PAPLL+P C INGY IP+ +RVIVN+ AI RDP W A Sbjct: 354 SETLRLHPPAPLLLPRECGQACEINGYHIPAKSRVIVNAWAIGRDPRLWTEA 405
>C71AP_ARATH (Q9STK8) Cytochrome P450 71A25 (EC 1.14.-.-)| Length = 490 Score = 125 bits (313), Expect = 1e-28 Identities = 67/168 (39%), Positives = 105/168 (62%), Gaps = 4/168 (2%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQLVIM 228 ++ K DD E ++ +HE D TD I LL +++E + + R +KA + + Sbjct: 232 KMGKDLDDFFEKVVQDHEDGDRR---DGTDLIDALLRVKREKSPGFEIERVSIKAITLDV 288 Query: 229 FGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIK 408 F G+DTS+ ++E+AM L+++P + +LQ EVR+ I KGK V EDD+ + YLKAVIK Sbjct: 289 FVGGSDTSFTLLEWAMTELLRHPKSLNRLQEEVRT-ICKGKSRVSEDDIQGMKYLKAVIK 347 Query: 409 ETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 E LRLH P P++ PH + D + Y IP+GT+V++N+ AI R+ ++W Sbjct: 348 EALRLHPPFPMMAPHESTEDVKLRDYHIPAGTQVMMNAWAIGREVATW 395
>C71AK_ARATH (Q9T0K2) Cytochrome P450 71A20 (EC 1.14.-.-)| Length = 495 Score = 124 bits (312), Expect = 1e-28 Identities = 78/186 (41%), Positives = 109/186 (58%), Gaps = 4/186 (2%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE- 183 P L +D IR + + V+K +D+ LE ++ EHE D D LL+IQ + Sbjct: 222 PSLSWIDRIRGLD-HKMEVVDKRFDEFLERVVKEHEEADKETRSDLVD---KLLTIQSDK 277 Query: 184 ---YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 + L + +K + MF AGT T+ +E+AM LM+NP +M KLQ E+RSS P+ Sbjct: 278 TGQFELEKSALKLIIWDMFLAGTATTLSFLEWAMTELMRNPKVMKKLQEEIRSSSPQDL- 336 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 V E + + YL+AVIKE LRL PAPLLVP + D + GY IP+GT+VIVN+ AI Sbjct: 337 FVTEKEAEKMNYLQAVIKEALRLRPPAPLLVPRVLSEDVKLKGYNIPAGTQVIVNAWAIQ 396 Query: 535 RDPSSW 552 RD ++W Sbjct: 397 RDTTTW 402
>C71E1_SORBI (O48958) Cytochrome P450 71E1 (EC 1.14.13.68)| (4-hydroxyphenylacetaldehyde oxime monooxygenase) Length = 531 Score = 124 bits (312), Expect = 1e-28 Identities = 69/171 (40%), Positives = 99/171 (57%), Gaps = 4/171 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN----LTREQVKAQL 219 R R+ D E +I +H P + D + L+++ KE++ TR+ VKA + Sbjct: 263 RRERIFNELDVFFEKVIDQHMDPARPVPDNGGDLVDVLINLCKEHDGTLRFTRDHVKAIV 322 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + F DTS + + +AM+ LM+ P ++ K QAEVR+++ K V +D + YLK Sbjct: 323 LDTFIGAIDTSSVTILWAMSELMRKPQVLRKAQAEVRAAVGDDKPRVNSEDAAKIPYLKM 382 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 V+KETLRLH PA LLVP M D I GY +P+ TRV VN+ AI RDP+SW Sbjct: 383 VVKETLRLHPPATLLVPRETMRDTTICGYDVPANTRVFVNAWAIGRDPASW 433
>C71AE_ARATH (P58045) Cytochrome P450 71A14 (EC 1.14.-.-)| Length = 497 Score = 124 bits (312), Expect = 1e-28 Identities = 67/172 (38%), Positives = 106/172 (61%), Gaps = 5/172 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQ 216 +A V+K + DL+E ++ EH ++ P L D++ LLS+++ + R +K Sbjct: 237 KAEEVSKAFGDLMEKVLQEHLDATDKPTL----DFVDVLLSLERHERNGVQIRRSDIKFL 292 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 ++ MF AGT+T+Y ++E+ M L+++P+ M KLQ E+R+ K + E+D+ + YLK Sbjct: 293 ILDMFLAGTETTYALLEWIMTELIRHPECMKKLQDEIRAKATKLILYISEEDVEDMKYLK 352 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 AV+KE LRLH P PLLVP D + GY I +GT+VI+N+ AI RD +W Sbjct: 353 AVVKEVLRLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTW 404
>C71BY_ARATH (Q9LIP3) Cytochrome P450 71B37 (EC 1.14.-.-)| Length = 500 Score = 124 bits (310), Expect = 2e-28 Identities = 77/184 (41%), Positives = 105/184 (57%), Gaps = 8/184 (4%) Frame = +1 Query: 28 IIRWM--VCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN---- 189 II W+ + G+ R + D E + H+ + D D LL ++KE Sbjct: 227 IIDWLTGLQGQRERSVRGLDAFYEQMFDLHKQGNKEGVEDFVDL---LLKLEKEETVLGY 283 Query: 190 --LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVI 363 LTR +KA L+ + G TS I M +AM LM+NP +M K+Q+E+R+ I GK M+ Sbjct: 284 GKLTRNHIKAVLMNVLLGGIGTSAITMTWAMTELMRNPRVMKKVQSEIRNQIG-GKSMIC 342 Query: 364 EDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDP 543 DD++ L YLK VI ET RLH PAPLLVP M++ INGYTIP+ TR+ VN I RDP Sbjct: 343 LDDIDQLHYLKMVINETWRLHPPAPLLVPREVMSEFEINGYTIPAKTRLYVNVWGIGRDP 402 Query: 544 SSWE 555 +W+ Sbjct: 403 DTWK 406
>C71D6_SOLCH (P93530) Cytochrome P450 71D6 (EC 1.14.-.-)| Length = 501 Score = 123 bits (308), Expect = 4e-28 Identities = 74/184 (40%), Positives = 107/184 (58%), Gaps = 13/184 (7%) Frame = +1 Query: 43 VCGRARR----VNKMWDDLLESLIHEHESKPAPALGDD-----TDYIHDLLSIQKEYNL- 192 V GRA+R V++ D ++E +I+EH+ A DD + I LL + + +L Sbjct: 226 VFGRAKRKLLNVHRKVDAIVEDVINEHKKNFATRKNDDHALGGENLIDVLLKLMNDKSLQ 285 Query: 193 ---TREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVI 363 + +KA ++ MF AGT+TS +AM +++NP ++ K QAEVR + + K Sbjct: 286 FPINNDNIKAIIIDMFAAGTETSSTTTVWAMVEMLKNPRVLAKAQAEVREAF-RNKVTFD 344 Query: 364 EDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDP 543 E+D+ L YLK VIKET+RLH P PLLVP + INGYTIP T+V+VN A+ RDP Sbjct: 345 ENDVEDLKYLKLVIKETMRLHAPIPLLVPRECRKETEINGYTIPVKTKVMVNVWALGRDP 404 Query: 544 SSWE 555 W+ Sbjct: 405 KYWD 408
>C71BP_ARATH (Q9LTL2) Cytochrome P450 71B25 (EC 1.14.-.-)| Length = 501 Score = 122 bits (307), Expect = 5e-28 Identities = 75/197 (38%), Positives = 113/197 (57%), Gaps = 12/197 (6%) Frame = +1 Query: 4 FPELLKLDIIRWM---VCGRARRVNKMW---DDLLESLIHEHESKPAPALGDDTDYIHDL 165 F +L + + W V G+ + ++K++ D+ L +I +H+ + P D +D + L Sbjct: 218 FSDLFPIPGLGWFIGFVSGQHKGLHKVFIEVDNFLNHMIDDHQKQNQPQ--DRSDIVGSL 275 Query: 166 LSI------QKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEV 327 L + K + LT + +K +F AG DTS I M +AMA L+ NP +M K+Q E+ Sbjct: 276 LDMIHNQEQDKSFKLTIDHLKGITQDIFLAGIDTSAITMIWAMAELVNNPRVMKKVQDEI 335 Query: 328 RSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTR 507 RS I K + E+D+ L YLK VIKETLRLH APLL+P MAD I GY IP T Sbjct: 336 RSCIGIKKERIEEEDVGKLQYLKLVIKETLRLHPAAPLLLPRETMADIKIQGYDIPRKTL 395 Query: 508 VIVNSRAIARDPSSWES 558 ++V++ ++ RDP W++ Sbjct: 396 LLVSAWSLGRDPKYWKN 412
>C71A4_SOLME (P37117) Cytochrome P450 71A4 (EC 1.14.-.-) (CYPLXXIA4) (P-450EG2)| Length = 507 Score = 122 bits (306), Expect = 7e-28 Identities = 74/178 (41%), Positives = 108/178 (60%), Gaps = 9/178 (5%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH---ESKPAPALGDDT-DYIHDLLSIQK----EYNLTREQV 207 + ++ K D L+S+I EH K A+ D+ D++ LL IQ ++ L R+ + Sbjct: 239 KVEKIAKKLDTFLDSVIEEHIIRNKKEEYAITDEAKDFVDVLLEIQNGKETDFPLQRDSL 298 Query: 208 KAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLA 387 KA L+ F AGTDT Y +++ MA +++ P M LQ EVR + +GK + EDDL ++ Sbjct: 299 KAILLDAFAAGTDTIYTNLDWTMADVLRQPRAMKTLQNEVRG-LAQGKSEITEDDLKNMQ 357 Query: 388 YLKAVIKETLRLHMPAPLLVPHLAMADCVING-YTIPSGTRVIVNSRAIARDPSSWES 558 YL+AVIKE+LRLH P LLVP +M D + G Y IP+ T+ ++N AI RDP SWE+ Sbjct: 358 YLRAVIKESLRLHPPNSLLVPRESMEDVKLLGYYHIPARTQALINVWAIGRDPLSWEN 415
>C71AJ_ARATH (Q9T0K0) Cytochrome P450 71A19 (EC 1.14.-.-)| Length = 490 Score = 122 bits (305), Expect = 9e-28 Identities = 76/182 (41%), Positives = 106/182 (58%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEY 186 P L +D IR + V+K +D+ LE ++ EHE D D LL+IQ + Sbjct: 225 PSLSWIDKIRGQD-HKMEEVDKRFDEFLERVVKEHEDANKDTRSDLVD---TLLTIQSD- 279 Query: 187 NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIE 366 + +K + MF AGT TS +E+AM LM+NP +M KLQ E+RSS +G V E Sbjct: 280 ---KSALKLIIWDMFLAGTATSLSFLEWAMTELMRNPKVMKKLQEEIRSSSRQGL-FVTE 335 Query: 367 DDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPS 546 + + YL+AVIKE LRL PAPL+VP + D + GY IP+GT+VI+N+ AI RD + Sbjct: 336 KEAEKMDYLQAVIKEALRLRPPAPLMVPRVFSEDVTLKGYNIPAGTQVIINAWAIQRDTT 395 Query: 547 SW 552 +W Sbjct: 396 TW 397
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 121 bits (304), Expect = 1e-27 Identities = 64/167 (38%), Positives = 101/167 (60%), Gaps = 4/167 (2%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN----LTREQVKAQLVIMF 231 V++ + DL+E ++ EH A D+++ LLSI+KE N + R +K ++ MF Sbjct: 241 VSRAYSDLMEKVVQEH----LEAGEHKADFVNILLSIEKEKNNGFKVQRNDIKFMILDMF 296 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 G TS ++E+ M L++NP+ M KLQ E+RS+I + E ++ ++ YLKAVIKE Sbjct: 297 IGGISTSSTLLEWIMTELIRNPECMKKLQNEIRSTIRPHGSYIKEKEVENMRYLKAVIKE 356 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 R+H P PL++P L D + GY I +GT V++N+ +I RDP+ W Sbjct: 357 VFRVHPPLPLILPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIW 403
>C71B3_ARATH (O65785) Cytochrome P450 71B3 (EC 1.14.-.-)| Length = 501 Score = 121 bits (303), Expect = 2e-27 Identities = 77/183 (42%), Positives = 108/183 (59%), Gaps = 11/183 (6%) Frame = +1 Query: 43 VCGRARRVNKMW---DDLLESLIHEHESKPAPALGDDTDYIHD--LLSIQKE-----YNL 192 V GR + ++K++ D LL +I H P D I D L +I K+ + L Sbjct: 230 VSGRHKTLHKVFVEVDTLLNHVIDGHLKNPEDKTNQDRPDIIDSILETIYKQEQDESFKL 289 Query: 193 TREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIP-KGKHMVIED 369 T + +K + ++ AG DTS I M +AMA L++NP +M K Q E+R+ I K K + E+ Sbjct: 290 TIDHLKGIIQNIYLAGVDTSAITMIWAMAELVKNPRVMKKAQEEIRTCIGIKQKERIEEE 349 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 D++ L YLK VIKETLRLH PAPLL+P MAD I GY IP T ++VN+ +I R+P Sbjct: 350 DVDKLQYLKLVIKETLRLHPPAPLLLPRETMADIKIQGYDIPRKTILLVNAWSIGRNPEL 409 Query: 550 WES 558 WE+ Sbjct: 410 WEN 412
>C71D7_SOLCH (P93531) Cytochrome P450 71D7 (EC 1.14.-.-)| Length = 500 Score = 121 bits (303), Expect = 2e-27 Identities = 67/169 (39%), Positives = 98/169 (57%), Gaps = 8/169 (4%) Frame = +1 Query: 79 DDLLESLIHEHESKPAPALGDDT----DYIHDLLSIQKEYNL----TREQVKAQLVIMFG 234 D ++E +I EH+ A DD D + L+ + + +L + +KA ++ +F Sbjct: 242 DSIVEDVIKEHKKNLATRKSDDAIGGEDLVDALVRLMNDKSLQFPINNDNIKAVIIDLFA 301 Query: 235 AGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKET 414 AGT+TS +AMA +++NP + K QA+VR + + K E+D+ L YLK VIKET Sbjct: 302 AGTETSSTTTVWAMAEMLKNPSVFAKAQAKVREAF-RDKVTFDENDVEELKYLKLVIKET 360 Query: 415 LRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWESA 561 +RLH P PLLVP + INGYTIP T+V+VN A+ RDP W+ A Sbjct: 361 MRLHAPVPLLVPRECREETEINGYTIPVKTKVMVNVWALGRDPKYWDDA 409
>C71B4_ARATH (O65786) Cytochrome P450 71B4 (EC 1.14.-.-)| Length = 504 Score = 121 bits (303), Expect = 2e-27 Identities = 73/187 (39%), Positives = 112/187 (59%), Gaps = 11/187 (5%) Frame = +1 Query: 31 IRWM---VCGRARRVNKMW---DDLLESLIHEHESKPAPALGDD-TDYIHDLLSIQKEY- 186 ++W V G+ +R+ ++ D ++ +H SK A D D I D++ +++Y Sbjct: 227 LKWFIGFVSGQHKRLYNVFNRVDTFFNHIVDDHHSKKATQDRPDMVDAILDMIDNEQQYA 286 Query: 187 --NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIP-KGKHM 357 LT + +K L ++ AG DTS I + +AMA L++NP +M K Q E+R+ I K + Sbjct: 287 SFKLTVDHLKGVLSNIYHAGIDTSAITLIWAMAELVRNPRVMKKAQDEIRTCIGIKQEGR 346 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 ++E+DL+ L YLK V+KETLRLH APLL+P MAD I GY IP ++VN+ +I R Sbjct: 347 IMEEDLDKLQYLKLVVKETLRLHPAAPLLLPRETMADIKIQGYDIPQKRALLVNAWSIGR 406 Query: 538 DPSSWES 558 DP SW++ Sbjct: 407 DPESWKN 413
>F3PH_PETHY (Q9SBQ9) Flavonoid 3'-monooxygenase (EC 1.14.13.21) (Flavonoid| 3'-hydroxylase) (Cytochrome P450 75B2) Length = 512 Score = 120 bits (302), Expect = 2e-27 Identities = 69/188 (36%), Positives = 113/188 (60%), Gaps = 6/188 (3%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEY 186 P+L LDI V + ++++ +D L ++ EH+ K G+ D + L+S++ + Sbjct: 227 PQLNWLDIQG--VAAKMKKLHARFDAFLTDILEEHKGK---IFGEMKDLLSTLISLKNDD 281 Query: 187 ------NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKG 348 LT ++KA L+ +F AGTDTS +E+A+A L++NP ++ + Q E+ + + Sbjct: 282 ADNDGGKLTDTEIKALLLNLFVAGTDTSSSTVEWAIAELIRNPKILAQAQQEIDKVVGRD 341 Query: 349 KHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRA 528 + +V E DL L YL+A++KET RLH PL +P +A C INGY IP G+ +++N A Sbjct: 342 R-LVGELDLAQLTYLEAIVKETFRLHPSTPLSLPRIASESCEINGYFIPKGSTLLLNVWA 400 Query: 529 IARDPSSW 552 IARDP++W Sbjct: 401 IARDPNAW 408
>C71A6_NEPRA (O04164) Cytochrome P450 71A6 (EC 1.14.-.-) (Fragment)| Length = 511 Score = 120 bits (300), Expect = 3e-27 Identities = 72/181 (39%), Positives = 104/181 (57%), Gaps = 11/181 (6%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH----ESKPAPALGDDT--DYIHDLLSIQKEYNLTREQV-- 207 R V++ +D+ L +I EH + + +GD D++ LL Q+E + V Sbjct: 239 RIEEVSRTFDEFLGKVIQEHRVRDKREDTTVVGDTVGLDFVDLLLQFQRENERSSSPVDD 298 Query: 208 ---KAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLN 378 KA ++ MF AGTDT+ +E+A++ L++NP M LQ EVR + K + E DL Sbjct: 299 LTIKAVILDMFLAGTDTTVTALEWALSELIKNPRAMKILQKEVRG-VAGSKGEIEESDLE 357 Query: 379 HLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 + YLKAV+KE+LRLH P PLLVP + D + GY + SGTRV++N AI RD S WE Sbjct: 358 KMPYLKAVMKESLRLHAPVPLLVPRESTRDTKVLGYDVASGTRVLINCWAIGRDSSVWEE 417 Query: 559 A 561 + Sbjct: 418 S 418
>C71AD_ARATH (O49342) Cytochrome P450 71A13 (EC 1.14.-.-)| Length = 497 Score = 119 bits (298), Expect = 6e-27 Identities = 63/171 (36%), Positives = 102/171 (59%), Gaps = 4/171 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN----LTREQVKAQL 219 + + V++ + DL++ ++ EH A D D++ LLSI+K+ N + R +K + Sbjct: 237 KIKEVSRGFSDLMDKVVQEH----LEASNDKADFVDILLSIEKDKNSGFQVQRNDIKFMI 292 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + MF GT T+ ++E+ M L+++P M KLQ E+RS+I + E ++ ++ YLKA Sbjct: 293 LDMFIGGTSTTSTLLEWTMTELIRSPKSMKKLQDEIRSTIRPHGSYIKEKEVENMKYLKA 352 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 VIKE LRLH P+++P L D + GY I +GT VI+N+ AI RD + W Sbjct: 353 VIKEVLRLHPSLPMILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDTAIW 403
>C71D8_SOYBN (O81974) Cytochrome P450 71D8 (EC 1.14.-.-) (P450 CP7)| Length = 504 Score = 119 bits (298), Expect = 6e-27 Identities = 74/196 (37%), Positives = 111/196 (56%), Gaps = 10/196 (5%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPAL------GDDTDYIHDL 165 FP L L ++ + V++ D +LE ++ +H K + D + L Sbjct: 220 FPSLKPLHLLTRQKA-KVEHVHQRADKILEDILRKHMEKRTRVKEGNGSEAEQEDLVDVL 278 Query: 166 LSIQK----EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 L +++ E +T E +KA + +F AGTDTS +E+AM+ +M+NP + K QAE+R Sbjct: 279 LRLKESGSLEVPMTMENIKAVIWNIFAAGTDTSASTLEWAMSEMMKNPKVKEKAQAELR- 337 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 I KGK ++ E DL L+YLK+VIKETLRLH P+ L+P + I+GY IP T+V+ Sbjct: 338 QIFKGKEIIRETDLEELSYLKSVIKETLRLHPPSQ-LIPRECIISTNIDGYEIPIKTKVM 396 Query: 514 VNSRAIARDPSSWESA 561 +N+ AI RDP W A Sbjct: 397 INTWAIGRDPQYWSDA 412
>C98A1_SORBI (O48956) Cytochrome P450 98A1 (EC 1.14.-.-)| Length = 512 Score = 119 bits (298), Expect = 6e-27 Identities = 65/164 (39%), Positives = 99/164 (60%) Frame = +1 Query: 67 NKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTD 246 N+ D L +I EH +K G ++ L +++++Y+L+ + V L M AG D Sbjct: 247 NERRDRLTMKIIEEH-AKSLKESGAKQHFVDALFTLKQQYDLSEDTVIGLLWDMITAGMD 305 Query: 247 TSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLH 426 T+ I +E+AMA L++NP + KLQ E+ + + + M +E D +L YL+AV+KE+LRLH Sbjct: 306 TTVISVEWAMAELVRNPRVQKKLQEELDRVVGRDRVM-LETDFQNLPYLQAVVKESLRLH 364 Query: 427 MPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 P PL++PH A + I GY IP G V+VN A+ARDP W + Sbjct: 365 PPTPLMLPHKASTNVKIGGYDIPKGANVMVNVWAVARDPKVWSN 408
>C71BQ_ARATH (Q9LTL0) Cytochrome P450 71B26 (EC 1.14.-.-)| Length = 500 Score = 119 bits (297), Expect = 8e-27 Identities = 68/142 (47%), Positives = 89/142 (62%), Gaps = 6/142 (4%) Frame = +1 Query: 148 DYIHDLLSIQKEY------NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMT 309 D + LL ++KE LTR +KA L+ + G DTS I M +AMA L +NP +M Sbjct: 266 DLVDVLLRLEKEEIVVGNGKLTRNHIKAILMNILLGGIDTSAITMTWAMAELAKNPRVMK 325 Query: 310 KLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYT 489 K+QAE+R+ I K K + DD + L YLK VIKET RLH P PLL+P + + INGYT Sbjct: 326 KVQAEIRNQI-KNKERISFDDTDKLEYLKMVIKETWRLHPPTPLLLPRDVITEFEINGYT 384 Query: 490 IPSGTRVIVNSRAIARDPSSWE 555 IP+ TR+ VN AI RDP +W+ Sbjct: 385 IPAKTRLHVNVWAIGRDPDTWK 406
>C71BA_ARATH (Q9LVD2) Cytochrome P450 71B10 (EC 1.14.-.-)| Length = 502 Score = 119 bits (297), Expect = 8e-27 Identities = 76/186 (40%), Positives = 105/186 (56%), Gaps = 10/186 (5%) Frame = +1 Query: 28 IIRWMVCGRARRVNKM--WDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEY----- 186 I+ W ARR + D E +I H K DD ++ LL ++KE Sbjct: 226 IVDWFTGLHARRERSVRDLDAFYEQMIDLHLQKNREESEDD--FVDLLLRLEKEEAVLGY 283 Query: 187 -NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGK--HM 357 LTR +KA L+ + G +TS I M +AMA L++NP +M K+Q+E+R+ I K + Sbjct: 284 GKLTRNHIKAILMNILLGGINTSAITMTWAMAELIRNPRVMKKVQSEIRAQIGKNNKTRI 343 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 + D++NHL+YL VIKET RLH APLLVP +++ INGYTI TR+ VN AI R Sbjct: 344 ISLDEINHLSYLNMVIKETCRLHPVAPLLVPREVISEFKINGYTIQPKTRLHVNVWAIGR 403 Query: 538 DPSSWE 555 DP W+ Sbjct: 404 DPEIWK 409
>C71AO_ARATH (Q9STK9) Cytochrome P450 71A24 (EC 1.14.-.-)| Length = 486 Score = 118 bits (296), Expect = 1e-26 Identities = 65/172 (37%), Positives = 105/172 (61%), Gaps = 4/172 (2%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQ 216 G+ +++ D+ LE ++ +H G D++ LL+I++E + + R +KA Sbjct: 229 GQLIKISNDLDEFLERVVQDHVDGD----GHKNDFVDFLLTIEREKSVGFEIDRLSIKAI 284 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 ++ +F DT+Y ++E+AM L+ + + + +LQ EVR + K K V EDDL + YLK Sbjct: 285 ILDVFVGDMDTTYTLLEWAMTELLCHHECLDRLQEEVRM-VCKDKSGVSEDDLQDMKYLK 343 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 AVIKETLRLH P PL+VPH + D + Y IP+GT V++N+ AI R+ ++W Sbjct: 344 AVIKETLRLHPPLPLMVPHESTHDVKLRDYHIPAGTHVMINAWAIGREAATW 395
>C71A2_SOLME (P37118) Cytochrome P450 71A2 (EC 1.14.-.-) (CYPLXXIA2) (P-450EG4)| Length = 505 Score = 118 bits (295), Expect = 1e-26 Identities = 72/179 (40%), Positives = 109/179 (60%), Gaps = 10/179 (5%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH----ESKPAPALGDDTDYIHDLLSIQK----EYNLTREQV 207 + ++V K D LE +I EH + + + G+ D++ LL IQ ++ L R+ + Sbjct: 238 KVKKVAKELDMFLEIVIEEHIIRKKKEEYTSTGEAKDFVDVLLEIQNGNETDFPLQRDSL 297 Query: 208 KAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLA 387 KA L+ F AGTDT++ +++ MA L++ P + LQ EVR + +GK + EDDL ++ Sbjct: 298 KAILLDSFAAGTDTTFATLDWTMAELLRQPRALKTLQDEVR-GLAQGKSEITEDDLKNMQ 356 Query: 388 YLKAVIKETLRLH-MPAPLLVPHLAMADCVING-YTIPSGTRVIVNSRAIARDPSSWES 558 YL+AVIKE+LRLH LLVP +M D + G Y IP+ T+ I+N+ AI RDP SWE+ Sbjct: 357 YLRAVIKESLRLHPTQESLLVPRESMEDVNLLGYYHIPARTQAIINAWAIGRDPLSWEN 415
>C75A1_PETHY (P48418) Flavonoid 3',5'-hydroxylase 1 (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A1) (CYPLXXVA1) Length = 506 Score = 117 bits (292), Expect = 3e-26 Identities = 63/171 (36%), Positives = 101/171 (59%), Gaps = 2/171 (1%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALG--DDTDYIHDLLSIQKEYNLTREQVKAQLVI 225 R +R++K +D LL + EH++ G D D + + + L+ +KA L+ Sbjct: 238 RMKRLHKKFDALLTKMFDEHKATTYERKGKPDFLDVVMENGDNSEGERLSTTNIKALLLN 297 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +F AGTDTS +E+A+A +M+NP ++ K QAE+ I + + + +E D+ +L YL+A+ Sbjct: 298 LFTAGTDTSSSAIEWALAEMMKNPAILKKAQAEMDQVIGRNRRL-LESDIPNLPYLRAIC 356 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 KET R H PL +P ++ C+++GY IP TR+ VN AI RDP WE+ Sbjct: 357 KETFRKHPSTPLNLPRISNEPCIVDGYYIPKNTRLSVNIWAIGRDPQVWEN 407
>C71BN_ARATH (Q9LTM0) Cytochrome P450 71B23 (EC 1.14.-.-)| Length = 501 Score = 116 bits (290), Expect = 5e-26 Identities = 67/180 (37%), Positives = 105/180 (58%), Gaps = 8/180 (4%) Frame = +1 Query: 43 VCGRARRVNKMWDDL---LESLIHEHESKPAPALG--DDTDYIHDLLSIQKE---YNLTR 198 + G+++ +N+++ DL ++ +H L D D + D+++ Q + + LT Sbjct: 231 ITGQSKSLNEIFADLDGFFNQVLDDHLKPGRKVLETPDVVDVMIDMMNKQSQDGSFKLTT 290 Query: 199 EQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLN 378 + +K + +F AG +TS + +AM L++NP +M K+Q EVR+ + + + + E DLN Sbjct: 291 DHIKGIISDIFLAGVNTSATTILWAMTELIRNPRVMKKVQDEVRTVLGEKRDRITEQDLN 350 Query: 379 HLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 L Y K VIKET RLH APLL+P AMA I GY IP T+++VN AI RDP WE+ Sbjct: 351 QLNYFKLVIKETFRLHPAAPLLLPREAMAKIKIQGYDIPEKTQIMVNVYAIGRDPDLWEN 410
>C71BW_ARATH (Q9LIP5) Cytochrome P450 71B35 (EC 1.14.-.-)| Length = 500 Score = 116 bits (290), Expect = 5e-26 Identities = 72/175 (41%), Positives = 103/175 (58%), Gaps = 6/175 (3%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEY------NLTREQVK 210 GR R + + E + H K G++ D++ LL ++KE LTR +K Sbjct: 235 GRRERSKRDLNAFFEQMFDLH--KEGKKEGNE-DFVDLLLRLEKEEAVLGNDKLTRNHIK 291 Query: 211 AQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAY 390 A L+ + AG DTS I M +AM L +NP +M K+Q+E+R+ + + M+ +D++ L Y Sbjct: 292 AILLDVLLAGIDTSAITMTWAMTELARNPRVMKKVQSEIRTQMGN-RSMISFEDMDQLEY 350 Query: 391 LKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LK VIKET RLH PLL+P AM++ INGYTIP TR+ VN AI RDP +W+ Sbjct: 351 LKMVIKETWRLHPTTPLLLPREAMSEFDINGYTIPVKTRLHVNVWAIGRDPDTWK 405
>C75A5_EUSGR (Q96418) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A5) Length = 510 Score = 116 bits (290), Expect = 5e-26 Identities = 69/182 (37%), Positives = 103/182 (56%), Gaps = 6/182 (3%) Frame = +1 Query: 31 IRWM----VCGRARRVNKMWDDLLESLIHEHESKPAPALG--DDTDYIHDLLSIQKEYNL 192 I WM + G +R++K +D LL L+ EH + G D D++ + L Sbjct: 231 IAWMDLQGIQGGMKRLHKKFDALLTRLLEEHTASAHERKGSPDFLDFVVANRDNSEGERL 290 Query: 193 TREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDD 372 +KA L+ MF AGTDTS V+E+A+A L++NP ++ + Q E+ I + + +E D Sbjct: 291 HTVNIKALLLNMFTAGTDTSSSVIEWALAELLKNPIILKRAQEEMDGVIGRDRRF-LEAD 349 Query: 373 LNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ++ L YL+A+ KE R H PL +P +A C +NG+ IP GTR+ VN AI RDPS W Sbjct: 350 ISKLPYLQAICKEAFRKHPSTPLNLPRIASQACEVNGHYIPKGTRLSVNIWAIGRDPSLW 409 Query: 553 ES 558 E+ Sbjct: 410 EN 411
>C71BS_ARATH (Q9SAE3) Cytochrome P450 71B28 (EC 1.14.-.-)| Length = 490 Score = 116 bits (290), Expect = 5e-26 Identities = 65/190 (34%), Positives = 111/190 (58%), Gaps = 7/190 (3%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMW---DDLLESLIHEHESKPAPALGDDTDYIHDLLSI 174 FP L+ +I W+ R +R+N+++ D ++++ +H KP D D + D++ Sbjct: 219 FPGLMGR-LIEWIFSER-KRLNRLYSEVDTFFQNILDDH-LKPGRESSDIIDVMIDMMKK 275 Query: 175 QKE----YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIP 342 Q++ + T + +K + +F AG TS + +AM L++NP +M K+Q E+R+++ Sbjct: 276 QEKEGDSFKFTTDHLKGMISDIFLAGVGTSSTTLIWAMTELIRNPRVMKKVQDEIRTTLG 335 Query: 343 KGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNS 522 K + E+DLN L Y K ++KE RLH APLL+P ++ I GY IP+ T++++N+ Sbjct: 336 DKKERITEEDLNQLHYFKLMVKEIFRLHPAAPLLLPRETLSHVKIQGYDIPAKTQIMINA 395 Query: 523 RAIARDPSSW 552 AIARDP W Sbjct: 396 YAIARDPKLW 405
>C71BX_ARATH (Q9LIP4) Cytochrome P450 71B36 (EC 1.14.-.-)| Length = 500 Score = 115 bits (289), Expect = 6e-26 Identities = 72/184 (39%), Positives = 102/184 (55%), Gaps = 8/184 (4%) Frame = +1 Query: 28 IIRWM--VCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN---- 189 II W+ + G+ R + D E + H+ + D D LL ++KE Sbjct: 227 IIDWLTGLHGQRERSVRALDAFYEQMFDLHKQGNKEGVEDFVDL---LLRLEKEETVIGY 283 Query: 190 --LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVI 363 LTR +KA L+ + G TS I M +AM LM+NP +M K+Q+E+R+ I K K M+ Sbjct: 284 GKLTRNHIKAILMNVLIGGIGTSAITMTWAMTELMRNPRVMKKVQSEIRNQIGK-KSMIT 342 Query: 364 EDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDP 543 DD++ L YLK VI ET RLH P+P L+P M++ +N Y IP TR+ VN AI RDP Sbjct: 343 LDDIDQLHYLKMVINETWRLHPPSPFLIPRQVMSEFELNDYVIPVKTRLYVNVWAIGRDP 402 Query: 544 SSWE 555 +W+ Sbjct: 403 DTWK 406
>C75A7_EUSGR (O04790) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A7) Length = 510 Score = 115 bits (289), Expect = 6e-26 Identities = 69/182 (37%), Positives = 103/182 (56%), Gaps = 6/182 (3%) Frame = +1 Query: 31 IRWM----VCGRARRVNKMWDDLLESLIHEHESKPAPALG--DDTDYIHDLLSIQKEYNL 192 I WM + G +R++K +D LL L+ EH + G D D++ + L Sbjct: 231 IAWMDLQGIQGGMKRLHKKFDALLTRLLEEHTASAHERKGSPDFLDFVVANGDNSEGERL 290 Query: 193 TREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDD 372 +KA L+ MF AGTDTS V+E+A+A L++NP ++ + Q E+ I + + +E D Sbjct: 291 QTVNIKALLLNMFTAGTDTSSSVIEWALAELLKNPIILRRAQEEMDGVIGRDRRF-LEAD 349 Query: 373 LNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ++ L YL+A+ KE R H PL +P +A C +NG+ IP GTR+ VN AI RDPS W Sbjct: 350 ISKLPYLQAICKEAFRKHPSTPLNLPRIASQACEVNGHYIPKGTRLSVNIWAIGRDPSVW 409 Query: 553 ES 558 E+ Sbjct: 410 EN 411
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 115 bits (289), Expect = 6e-26 Identities = 72/187 (38%), Positives = 108/187 (57%), Gaps = 1/187 (0%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQ-K 180 FP L K+D + + G AR +K+ + + LI E GD D ++ Sbjct: 219 FPVLKKIDP-QGIKRGMARHFSKVLG-IFDQLIEERMRTGRFEQGDVLDVCLKMMQDNPN 276 Query: 181 EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMV 360 E+N T +KA + +F AGTDT+ I +E+AM L++ P +M+K + E+ I KG +V Sbjct: 277 EFNHTN--IKALFLDLFVAGTDTTSITIEWAMTELLRKPHIMSKAKEELEKVIGKGS-IV 333 Query: 361 IEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 EDD+ L YL ++KE LRLH P+PLL+P + ++GYTIP+GT V VN+ AI RD Sbjct: 334 KEDDVLRLPYLSCIVKEVLRLHPPSPLLLPRKVVTQVELSGYTIPAGTLVFVNAWAIGRD 393 Query: 541 PSSWESA 561 P+ W+ + Sbjct: 394 PTVWDDS 400
>C71BO_ARATH (Q9LTL8) Cytochrome P450 71B24 (EC 1.14.-.-)| Length = 498 Score = 115 bits (287), Expect = 1e-25 Identities = 70/183 (38%), Positives = 108/183 (59%), Gaps = 11/183 (6%) Frame = +1 Query: 43 VCGRARRVNKMW---DDLLESLIHEHESKPAPALGDDT----DYIHDLLSIQKE---YNL 192 V G ++++K++ D LL +I +H + D D + D++ Q++ + L Sbjct: 227 VSGHNKKLHKVFVEVDTLLNHIIDDHLKNSIEEITHDRPDIIDSLLDMIRKQEQGDSFKL 286 Query: 193 TREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIP-KGKHMVIED 369 T + +K + ++ AG DTS I M +AMA L++NP +M K+Q E+R+ I K + ED Sbjct: 287 TIDNLKGIIQDIYLAGVDTSAITMIWAMAELVKNPRVMKKVQDEIRTCIGIKQNEKIEED 346 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 D++ L YLK V+KETLRLH APLL+P M+ I GY IPS T ++VN +I RDP Sbjct: 347 DVDKLQYLKLVVKETLRLHPAAPLLLPRETMSQIKIQGYNIPSKTILLVNVWSIGRDPKH 406 Query: 550 WES 558 W++ Sbjct: 407 WKN 409
>C81E1_GLYEC (P93147) Cytochrome P450 81E1 (EC 1.14.13.89) (Isoflavone| 2'-hydroxylase) (P450 91A4) (CYP GE-3) Length = 499 Score = 115 bits (287), Expect = 1e-25 Identities = 65/170 (38%), Positives = 101/170 (59%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMF 231 R + ++ D L LI EH +K A D++ +L Q EY T + +K + M Sbjct: 243 RLKDISGKTDAFLRGLIEEHRTKKERA-NTMIDHLLNLQDSQPEY-YTDQIIKGLALAML 300 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 AGTD+S + +E++M+ L+ +P+++ K++ E+ + + + + +V E DL L YLK VI E Sbjct: 301 LAGTDSSAVTLEWSMSNLLNHPEVLKKVKDELDTHVGQDR-LVDESDLPKLTYLKNVINE 359 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWESA 561 TLRL+ PAPLL+PH +C I GY +P T V++N+ AI RDP W A Sbjct: 360 TLRLYTPAPLLLPHSTSDECNIGGYKVPQDTIVLINAWAIHRDPELWTEA 409
>C75A2_SOLME (P37120) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A2) (CYPLXXVA2) (P-450EG1) Length = 513 Score = 115 bits (287), Expect = 1e-25 Identities = 65/169 (38%), Positives = 96/169 (56%), Gaps = 2/169 (1%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALG--DDTDYIHDLLSIQKEYNLTREQVKAQLVIMF 231 ++++K +DDLL + EHE+ G D D+I + L+ +KA L+ +F Sbjct: 243 KKLHKKFDDLLTKMFEEHEATSNERKGKPDFLDFIMANRDNSEGERLSITNIKALLLNLF 302 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 AGTDTS V+E+A+ +M+NP + K Q E+ I K + IE D+ +L YL+A+ KE Sbjct: 303 TAGTDTSSSVIEWALTEMMKNPTIFKKAQQEMDQIIGKNRRF-IESDIPNLPYLRAICKE 361 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 R H PL +P ++ C I+GY IP TR+ VN AI RDP WE+ Sbjct: 362 AFRKHPSTPLNLPRVSSDACTIDGYYIPKNTRLSVNIWAIGRDPDVWEN 410
>C76C1_ARATH (O64636) Cytochrome P450 76C1 (EC 1.14.-.-)| Length = 512 Score = 115 bits (287), Expect = 1e-25 Identities = 72/191 (37%), Positives = 112/191 (58%), Gaps = 6/191 (3%) Frame = +1 Query: 4 FPELLKLD----IIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLS 171 FP L LD + + VC R+ +++ +++ I E S+ P D++ +LL Sbjct: 231 FPFLRFLDLQGNVKTFKVC--TERLVRVFRGFIDAKIAEKSSQNNPKDVSKNDFVDNLLD 288 Query: 172 IQ-KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKG 348 + E L+ ++ L+ MF AGTDTS +E+AM L++NP M K QAE+ I G Sbjct: 289 YKGDESELSISDIEHLLLDMFTAGTDTSSSTLEWAMTELLKNPKTMAKAQAEIDCVI--G 346 Query: 349 KHMVIED-DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSR 525 ++ ++E+ D++ L YL+AV+KET RLH P PLL+P A +D I G+ + T+V+VN Sbjct: 347 QNGIVEESDISKLPYLQAVVKETFRLHTPVPLLIPRKAESDAEILGFMVLKDTQVLVNVW 406 Query: 526 AIARDPSSWES 558 AI RDPS W++ Sbjct: 407 AIGRDPSVWDN 417
>C71B9_ARATH (O64718) Cytochrome P450 71B9 (EC 1.14.-.-)| Length = 500 Score = 115 bits (287), Expect = 1e-25 Identities = 76/189 (40%), Positives = 108/189 (57%), Gaps = 11/189 (5%) Frame = +1 Query: 28 IIRWMVCGRARRVNKMWDDL---LESL--IHEHESKPAPALGDDTDYIHDLLSIQKEYN- 189 II W+ G RR K DL + + +H+ E+K D++ LL ++KE Sbjct: 227 IIDWLT-GLQRRREKSVKDLDVFYQQMFDLHKQENKQGVE-----DFVDLLLKLEKEETV 280 Query: 190 -----LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 LTR VKA L+ + +TS + M +AMA L++NP +M K+Q+E+R+ + K Sbjct: 281 LGYGKLTRNHVKAILMNVLLGAINTSAMTMTWAMAELIRNPRVMKKVQSEIRNQMIN-KS 339 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 ++ DD++HL YLK VIKET RLH P PLL+P M++ INGY I T + VN AI Sbjct: 340 VITLDDIDHLPYLKMVIKETWRLHPPVPLLLPREVMSEFEINGYKIQPKTLLYVNVWAIG 399 Query: 535 RDPSSWESA 561 RDP SW+ A Sbjct: 400 RDPDSWKDA 408
>C81D1_ARATH (Q9FG65) Cytochrome P450 81D1 (EC 1.14.-.-)| Length = 502 Score = 114 bits (286), Expect = 1e-25 Identities = 64/171 (37%), Positives = 105/171 (61%), Gaps = 3/171 (1%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK---EYNLTREQVKAQLV 222 R +++ + D L+ LI + + T I LL +QK EY T + +K ++ Sbjct: 247 RVKKLGEETDKFLQGLIDDKRGQQETG----TTMIDHLLVLQKSDIEY-YTDQIIKGIIL 301 Query: 223 IMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 IM AGT+TS + +E+A++ L+ +PD+++K + E+ + + + ++ E DL+ L YLK + Sbjct: 302 IMVIAGTNTSAVTLEWALSNLLNHPDVISKARDEIDNRVGLDR-LIEEADLSELPYLKNI 360 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 + ETLRLH PLLVPH+A DC I Y +P GT ++VN+ AI RDP++W+ Sbjct: 361 VLETLRLHPATPLLVPHMASEDCKIGSYDMPRGTTLLVNAWAIHRDPNTWD 411
>C75A3_PETHY (P48419) Flavonoid 3',5'-hydroxylase 2 (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A3) (CYPLXXVA3) Length = 508 Score = 113 bits (283), Expect = 3e-25 Identities = 61/169 (36%), Positives = 98/169 (57%), Gaps = 2/169 (1%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALG--DDTDYIHDLLSIQKEYNLTREQVKAQLVIMF 231 +R++K +D LL + EH++ G D D + + + L+ +KA L+ +F Sbjct: 240 KRLHKKFDALLTKMFDEHKATSYERKGKPDFLDCVMENRDNSEGERLSTTNIKALLLNLF 299 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 AGTDTS +E+A+A +M+NP ++ K Q E+ I + + +E D+ +L YL+A+ KE Sbjct: 300 TAGTDTSSSAIEWALAEMMKNPAILKKAQGEMDQVIGNNRRL-LESDIPNLPYLRAICKE 358 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 T R H PL +P ++ C+++GY IP TR+ VN AI RDP WE+ Sbjct: 359 TFRKHPSTPLNLPRISNEPCIVDGYYIPKNTRLSVNIWAIGRDPEVWEN 407
>C76C2_ARATH (O64637) Cytochrome P450 76C2 (EC 1.14.-.-)| Length = 512 Score = 113 bits (283), Expect = 3e-25 Identities = 62/142 (43%), Positives = 91/142 (64%), Gaps = 2/142 (1%) Frame = +1 Query: 142 DTDYIHDLLSIQK--EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKL 315 + D++ LL + + E L + L+ +FGAGTDT+ +E+AMA L++NP+ M K Sbjct: 279 ERDFVDVLLDLTEGDEAELNTNDIVHLLLDLFGAGTDTNSSTVEWAMAELLRNPETMVKA 338 Query: 316 QAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIP 495 QAE+ I + K +V E D++ L YL+AV+KET RLH APLLVP A +D + G+ +P Sbjct: 339 QAEIDCVIGQ-KGVVEESDISALPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLGFMVP 397 Query: 496 SGTRVIVNSRAIARDPSSWESA 561 T+V VN AI RDP+ WE++ Sbjct: 398 KDTQVFVNVWAIGRDPNVWENS 419
>C80B2_ESCCA (O64900) (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2 (EC| 1.14.13.71) (Cytochrome P450 80B2) Length = 488 Score = 113 bits (282), Expect = 4e-25 Identities = 68/185 (36%), Positives = 104/185 (56%), Gaps = 2/185 (1%) Frame = +1 Query: 4 FPELLKLDII--RWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQ 177 FP L K D+ R V + + +W +L+ E K A + D +D + + Sbjct: 220 FPMLGKFDLFGQRKEVAECLKGIYAIWGAMLQ------ERKLAKKV-DGYQSKNDFVDVC 272 Query: 178 KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 + L Q+ A L+ +FGAGT+TS +E+AM L +NP + KL++E+++ + G+ Sbjct: 273 LDSGLNDYQINALLMELFGAGTETSASTIEWAMTELTKNPKITAKLRSELQTVV--GERS 330 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 V E D +L YL+A +KETLRLH P PLL+P A+ C I YTIP +++VN+ I R Sbjct: 331 VKESDFPNLPYLEATVKETLRLHPPTPLLLPRRALETCTILNYTIPKDCQIMVNAWGIGR 390 Query: 538 DPSSW 552 DP +W Sbjct: 391 DPKTW 395
>C80B1_ESCCA (O64899) (S)-N-methylcoclaurine 3'-hydroxylase isozyme 1 (EC| 1.14.13.71) (Cytochrome P450 80B1) (Fragment) Length = 487 Score = 112 bits (281), Expect = 5e-25 Identities = 67/185 (36%), Positives = 104/185 (56%), Gaps = 2/185 (1%) Frame = +1 Query: 4 FPELLKLDII--RWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQ 177 FP L K D+ R V + + +W +L+ E K A + D +D + + Sbjct: 219 FPMLGKFDLFGQRKEVAECLKGIYAIWGAMLQ------ERKLAKKV-DGYKSKNDFVDVC 271 Query: 178 KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 + L Q+ A L+ +FGAGT+TS +E+AM L +NP + K+++E+++ + G+ Sbjct: 272 LDSGLNDYQINALLMELFGAGTETSASTIEWAMTELTKNPKITAKIRSEIQTVV--GERS 329 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 V E D +L YL+A +KETLRLH P PLL+P A+ C I YTIP +++VN+ I R Sbjct: 330 VKESDFPNLPYLEATVKETLRLHPPTPLLLPRRALETCTILNYTIPKDCQIMVNAWGIGR 389 Query: 538 DPSSW 552 DP +W Sbjct: 390 DPKTW 394
>C76C4_ARATH (O64635) Cytochrome P450 76C4 (EC 1.14.-.-)| Length = 511 Score = 112 bits (280), Expect = 7e-25 Identities = 70/187 (37%), Positives = 105/187 (56%), Gaps = 2/187 (1%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK- 180 F L L R + G R+ +++ +++ I E + D++ LL + + Sbjct: 232 FMGFLDLQGNRKAMRGLTERLFRVFRGFMDAKIAEKSLGNYSKDVSNRDFLDSLLILNEG 291 Query: 181 -EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 E L ++ L+ MF AGTDTS +E+AMA L++NP M K QAE+ + + + Sbjct: 292 DEAELDNNDIEHLLLDMFTAGTDTSSSTLEWAMAELLRNPKTMVKAQAEMDRVLGQNS-V 350 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 V E D++ L YL+AV+KET RLH APLLVP A +D + G+ +P T+V+VN AI R Sbjct: 351 VQESDISGLPYLQAVVKETFRLHPAAPLLVPRKAESDVEVLGFMVPKDTQVLVNVWAIGR 410 Query: 538 DPSSWES 558 DPS WE+ Sbjct: 411 DPSVWEN 417
>C98A2_SOYBN (O48922) Cytochrome P450 98A2 (EC 1.14.-.-)| Length = 509 Score = 112 bits (280), Expect = 7e-25 Identities = 65/178 (36%), Positives = 101/178 (56%), Gaps = 3/178 (1%) Frame = +1 Query: 31 IRWMVC---GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTRE 201 +RWM G + D L +++ EH + G ++ LL++Q +Y+L+ + Sbjct: 229 LRWMFPLEEGAFAKHGARRDRLTRAIMAEHTEARKKSGGAKQHFVDALLTLQDKYDLSED 288 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 + L M AG DT+ I +E+AMA L++NP + K+Q E+ I + M E D ++ Sbjct: 289 TIIGLLWDMITAGMDTTAISVEWAMAELIRNPRVQQKVQEELDRVIGLERVMT-EADFSN 347 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 L YL+ V KE +RLH P PL++PH A A+ + GY IP G+ V VN A+ARDP+ W+ Sbjct: 348 LPYLQCVTKEAMRLHPPTPLMLPHRANANVKVGGYDIPKGSNVHVNVWAVARDPAVWK 405
>C71B7_ARATH (Q96514) Cytochrome P450 71B7 (EC 1.14.-.-)| Length = 504 Score = 112 bits (280), Expect = 7e-25 Identities = 61/187 (32%), Positives = 109/187 (58%), Gaps = 13/187 (6%) Frame = +1 Query: 31 IRWMV---CGRARRVNKMWDDL---LESLIHEHESKPAPALGDDTDYIHDLLSIQKE--- 183 + W+V G+ + +N ++ +L ++++ +H KP + ++ D + +L + K+ Sbjct: 226 VGWLVDRISGQNKTLNNVFSELDTFFQNVLDDH-IKPGRQVSENPDVVDVMLDLMKKQEK 284 Query: 184 ----YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGK 351 + LT + +K + +F AG +TS + + +AMA L++NP +M K+Q E+R+++ K Sbjct: 285 DGESFKLTTDHLKGIISDIFLAGVNTSAVTLNWAMAELIRNPRVMKKVQDEIRTTLGDKK 344 Query: 352 HMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAI 531 + E DL+ + Y K V+KE RLH APLL+P M+ I GY IP T++++N +I Sbjct: 345 QRITEQDLSQVHYFKLVVKEIFRLHPAAPLLLPRETMSHVKIQGYDIPVKTQMMINIYSI 404 Query: 532 ARDPSSW 552 ARDP W Sbjct: 405 ARDPKLW 411
>C98A3_ARATH (O22203) Cytochrome P450 98A3 (EC 1.14.-.-)| Length = 508 Score = 112 bits (279), Expect = 9e-25 Identities = 58/160 (36%), Positives = 95/160 (59%) Frame = +1 Query: 79 DDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYI 258 D L +++ EH + G ++ LL+++ +Y+L+ + + L M AG DT+ I Sbjct: 247 DRLTRAIMEEHTLARQKSSGAKQHFVDALLTLKDQYDLSEDTIIGLLWDMITAGMDTTAI 306 Query: 259 VMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAP 438 E+AMA +++NP + K+Q E + + ++ E D + L YL+ V+KE+ RLH P P Sbjct: 307 TAEWAMAEMIKNPRVQQKVQEEFDRVVGLDR-ILTEADFSRLPYLQCVVKESFRLHPPTP 365 Query: 439 LLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 L++PH + AD I GY IP G+ V VN A+ARDP+ W++ Sbjct: 366 LMLPHRSNADVKIGGYDIPKGSNVHVNVWAVARDPAVWKN 405
>C71BJ_ARATH (Q9LTM4) Cytochrome P450 71B19 (EC 1.14.-.-)| Length = 502 Score = 111 bits (277), Expect = 2e-24 Identities = 66/182 (36%), Positives = 101/182 (55%), Gaps = 10/182 (5%) Frame = +1 Query: 37 WMV---CGRARRVNKMW---DDLLESLIHEHESKPAPALGDDT-DYIHDLLSIQKE---Y 186 W+V G+ +R+N ++ D L + +I +H + +D D + D++ Q E Sbjct: 228 WLVDWFSGQHKRLNDVFYKLDALFQHVIDDHLNPGRSKEHEDIIDSMLDVIHKQGEDSSL 287 Query: 187 NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIE 366 LT + +K L +F AG DT I M +A+ L++NP L+ K+Q ++R + K + E Sbjct: 288 ELTIDHIKGFLANIFLAGIDTGAITMIWAVTELVKNPKLIKKVQGDIREQLGSNKERITE 347 Query: 367 DDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPS 546 +D+ + YLK VIKET RLH APL++P MA + GY IP R++VN AI RDP Sbjct: 348 EDIEKVPYLKMVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRILVNVSAIGRDPK 407 Query: 547 SW 552 W Sbjct: 408 LW 409
>C71B6_ARATH (O65787) Cytochrome P450 71B6 (EC 1.14.-.-)| Length = 503 Score = 110 bits (276), Expect = 2e-24 Identities = 65/165 (39%), Positives = 94/165 (56%), Gaps = 6/165 (3%) Frame = +1 Query: 79 DDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN------LTREQVKAQLVIMFGAG 240 D + I +H K D D I LL +Q + +T ++A ++ +F AG Sbjct: 251 DTFYQKAIVDHREKKKTE--DREDLIDVLLKLQSQETKLGSSRITDTHIRAIIMDLFVAG 308 Query: 241 TDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLR 420 DTS I +++ MA L ++P +M K+QAE+R + K +V DDL L Y+K VIKET R Sbjct: 309 VDTSVITLDWTMAELSRHPRVMKKVQAEIREHVGD-KGIVTYDDLEALVYMKMVIKETWR 367 Query: 421 LHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LH P+P+L+P AM + I GY I GTR+ VN+ AI R+P W+ Sbjct: 368 LHAPSPILIPREAMTNFKIKGYDIYPGTRIHVNAWAIGRNPDVWK 412
>C71BK_ARATH (Q9LTM3) Cytochrome P450 71B20 (EC 1.14.-.-)| Length = 502 Score = 109 bits (272), Expect = 6e-24 Identities = 67/184 (36%), Positives = 101/184 (54%), Gaps = 12/184 (6%) Frame = +1 Query: 37 WMV---CGRARRVNKMW---DDLLESLIHEHESKPAPALGDDTDYIHDLL-SIQKE---- 183 W+V G+ +R+N ++ D L + +I +H + + D I +L +I KE Sbjct: 228 WLVDWFSGQHKRLNDVFYKLDALFQHVIDDHLNPGRSK--EHEDIIDSMLDAIHKEGKDS 285 Query: 184 -YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMV 360 L + +K L +F AG DT + M +AM L++NP L+ K+Q E+R + K + Sbjct: 286 SLELIIDHIKGFLANIFLAGIDTGALTMIWAMTELVKNPKLIKKVQGEIREQLGSNKARI 345 Query: 361 IEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 E+D++ + YLK VIKET RLH APL++P MA + GY IP R++VN AI RD Sbjct: 346 TEEDIDKVPYLKMVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRILVNVSAIGRD 405 Query: 541 PSSW 552 P W Sbjct: 406 PKLW 409
>C71BH_ARATH (Q9LTM6) Cytochrome P450 71B17 (EC 1.14.-.-)| Length = 502 Score = 108 bits (271), Expect = 8e-24 Identities = 63/184 (34%), Positives = 102/184 (55%), Gaps = 9/184 (4%) Frame = +1 Query: 28 IIRWMVCGRARRVNKMW---DDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN--- 189 ++ W + G+ +R+N ++ D LL+ +I +H S P + D D + +L + + Sbjct: 229 LVDW-ISGQHKRLNDVFLKLDALLQHVIDDH-SNPGRSK-DHKDIVDVMLDVMHKQGKDD 285 Query: 190 ---LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMV 360 LT + +K L + AG DT + M + M L +NP++M K+Q E+R + + + Sbjct: 286 SLRLTIDHIKGLLTNIIIAGIDTGALTMIWTMTELARNPEIMKKVQGEIRDRLGNNRERI 345 Query: 361 IEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 ++DL+ + +L VIKET RLH APLL+P MA + GY IP R++VN+ AI RD Sbjct: 346 TKEDLDKVPFLNLVIKETFRLHPVAPLLLPRETMAHVKVQGYDIPPKRRILVNAWAIGRD 405 Query: 541 PSSW 552 P W Sbjct: 406 PKLW 409
>C71BG_ARATH (Q9LTM7) Cytochrome P450 71B16 (EC 1.14.-.-)| Length = 502 Score = 108 bits (269), Expect = 1e-23 Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 9/193 (4%) Frame = +1 Query: 1 DFPELLKLDIIRWMVCGRARRVNKMW---DDLLESLIHEHESKPAPALGDDTDYIHDLLS 171 DF + L + + G+ R +N ++ D L + +I +H S P D D + +L Sbjct: 219 DFFPIAGLGWLADWISGKHRWLNNVFFKLDALFQRVIDDH-SDPG-RWKDHKDIVDVMLD 276 Query: 172 IQKEYN------LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 + + LT + +K L + AG DT + M +AM L +NP+LM +Q E+R Sbjct: 277 VMHKQGKDDSLRLTIDHIKGFLTNIIIAGIDTGALTMIWAMTELARNPELMKNVQGEIRD 336 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 S K + ++DLN + +L VIKET RLH APLL+P M + GY IP R++ Sbjct: 337 SFGNNKERITKEDLNKVPFLNMVIKETFRLHPVAPLLLPRETMTHIKVQGYDIPPKRRIL 396 Query: 514 VNSRAIARDPSSW 552 VN+ AI RDP+ W Sbjct: 397 VNTWAIGRDPTLW 409
>C93A1_SOYBN (Q42798) Cytochrome P450 93A1 (EC 1.14.-.-)| Length = 509 Score = 107 bits (268), Expect = 2e-23 Identities = 62/162 (38%), Positives = 96/162 (59%) Frame = +1 Query: 70 KMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDT 249 K + D+L+ L+ HE + A E L ++ +KA ++ +F AGTDT Sbjct: 269 KQFKDMLDVLLDMHEDENA------------------EIKLDKKNIKAFIMDIFVAGTDT 310 Query: 250 SYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHM 429 S + +E+AMA L+ NPD++ K + E+ + + K + MV E D+ +L YL+A+++ETLRLH Sbjct: 311 SAVSIEWAMAELINNPDVLEKARQEIDAVVGKSR-MVEESDIANLPYLQAIVRETLRLHP 369 Query: 430 PAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 PL+V + V+ GY IP+ TR+ VN AI RDP+ WE Sbjct: 370 GGPLVVRE-SSKSAVVCGYDIPAKTRLFVNVWAIGRDPNHWE 410
>C71B5_ARATH (O65784) Cytochrome P450 71B5 (EC 1.14.-.-)| Length = 498 Score = 107 bits (268), Expect = 2e-23 Identities = 51/123 (41%), Positives = 76/123 (61%) Frame = +1 Query: 184 YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVI 363 Y +T + +K + +F AG + I M + M L ++P +M KLQ E+R+++ K + Sbjct: 282 YKVTDDHLKGLMSDVFLAGVNAGSITMIWTMTELSRHPRVMRKLQEEIRAALGPNKEKIT 341 Query: 364 EDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDP 543 E+DL + YLK VI+E RLH PAPLL+P L M+D I GY+IP T + +N+ I RDP Sbjct: 342 EEDLEKVEYLKMVIEEAFRLHPPAPLLLPRLTMSDINIQGYSIPKNTMIQINTYTIGRDP 401 Query: 544 SSW 552 +W Sbjct: 402 KNW 404
>C71BM_ARATH (Q9LTM1) Cytochrome P450 71B22 (EC 1.14.-.-)| Length = 500 Score = 107 bits (267), Expect = 2e-23 Identities = 59/146 (40%), Positives = 85/146 (58%), Gaps = 6/146 (4%) Frame = +1 Query: 139 DDTDYIHDLLS-IQKE-----YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPD 300 D +D I +L I KE + +T + +K + +F AG + I M +AM L ++P Sbjct: 263 DHSDIIGVMLDMINKESKVGSFQVTYDHLKGVMSDVFLAGVNAGAITMIWAMTELARHPR 322 Query: 301 LMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVIN 480 +M KLQ E+R + K + E DL + YLK VI+ET RLH PAPLL+P M+D I Sbjct: 323 VMKKLQQEIREILGDNKEKITEQDLEKVHYLKLVIEETFRLHPPAPLLLPRETMSDLKIQ 382 Query: 481 GYTIPSGTRVIVNSRAIARDPSSWES 558 GY IP T + +N+ +I RDP+ WE+ Sbjct: 383 GYNIPKNTMIEINTYSIGRDPNCWEN 408
>C71BL_ARATH (Q9LTM2) Cytochrome P450 71B21 (EC 1.14.-.-)| Length = 499 Score = 106 bits (264), Expect = 5e-23 Identities = 63/177 (35%), Positives = 96/177 (54%), Gaps = 7/177 (3%) Frame = +1 Query: 43 VCGRARRVNKMWDDLLESLIHEHESKPAPALGDD-TDYIHDLLS-IQKE-----YNLTRE 201 + G+ R++K + L H + P +D +D + +L I KE + +T + Sbjct: 230 ISGQHSRLHKAFARLSNFFQHVIDDHLKPWQSEDHSDIVGVMLDMINKESKVGSFKVTYD 289 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 +K + +F AG + I M +A+ L ++P +M KLQ E+R + K + E DL Sbjct: 290 HLKGVMSDVFLAGVNAGAITMIWALTELTRHPRVMKKLQQEIRELLGDNKEKITEQDLEK 349 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + YLK VI+ET RLH PAPLL+P M+D I GY IP T + +N+ AI RDP+ W Sbjct: 350 VHYLKLVIQETFRLHPPAPLLLPRETMSDVKIQGYNIPKNTMIEINTYAIGRDPNCW 406
>C80A1_BERST (P47195) Berbamunine synthase (EC 1.14.21.3) (Cytochrome P450 80)| (CYPLXXX) ((S)-N-methylcoclaurine oxidase [C-O phenol-coupling]) Length = 487 Score = 106 bits (264), Expect = 5e-23 Identities = 60/186 (32%), Positives = 100/186 (53%), Gaps = 2/186 (1%) Frame = +1 Query: 4 FPELLKLDI--IRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQ 177 FP L + D+ ++ + + + + K+W+ E L P P D+L + Sbjct: 222 FPVLARFDLHGLKRKMDEQFKLLIKIWEG--EVLARRANRNPEPK---------DMLDVL 270 Query: 178 KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 + Q+ A + FG G+DT+ ++E+A+A+L++NPD + KL+ E+ + + Sbjct: 271 IANDFNEHQINAMFMETFGPGSDTNSNIIEWALAQLIKNPDKLAKLREELDRVVGRSS-T 329 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 V E + L YL+A +KET+RL+ P +++PH M C + GYTIP G V VN+ AI R Sbjct: 330 VKESHFSELPYLQACVKETMRLYPPISIMIPHRCMETCQVMGYTIPKGMDVHVNAHAIGR 389 Query: 538 DPSSWE 555 DP W+ Sbjct: 390 DPKDWK 395
>C71AF_ARATH (P58046) Cytochrome P450 71A15 (EC 1.14.-.-)| Length = 496 Score = 105 bits (263), Expect = 7e-23 Identities = 67/189 (35%), Positives = 105/189 (55%), Gaps = 7/189 (3%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEH---ESKPAPALGDDTDYIHDLLSIQ 177 P L +D IR + RA V+K++ DL++ ++ EH +KP D++ LLS + Sbjct: 222 PCLAWIDQIRGLY-NRAEEVSKIFGDLMDKVVQEHLDATNKPTK------DFVDILLSFE 274 Query: 178 KE----YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPK 345 ++ + R +K ++ +F GT T+ ++E+ M L+++P+ M KLQ E+R Sbjct: 275 RQSKDGIEVRRSDIKFIILDIFLGGTTTTNSLLEWTMTELIRHPECMKKLQDEIRGDATN 334 Query: 346 GKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSR 525 +++ + YLKAVIKE LRLH P PLLV L D + GY I +GT+VI N+ Sbjct: 335 LTIYRSHEEVEDMKYLKAVIKEGLRLHPPFPLLVLRLLTQDVKLKGYDIAAGTQVITNAW 394 Query: 526 AIARDPSSW 552 AI RD +W Sbjct: 395 AIQRDIVTW 403
>C75A4_GENTR (Q96581) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A4) Length = 516 Score = 105 bits (261), Expect = 1e-22 Identities = 67/181 (37%), Positives = 103/181 (56%), Gaps = 7/181 (3%) Frame = +1 Query: 31 IRWM----VCGRARRVNKMWDDLLESLIHEHE--SKPAPALGDDTDYIHDLLSIQKEYNL 192 I WM + G +R++K +D LL L+ +H+ S+ D D++ L Sbjct: 235 IGWMDLQGIEGGMKRLHKKFDVLLTRLLDDHKRTSQERKQKPDFLDFVIANGDNSDGERL 294 Query: 193 TREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDD 372 + +KA L+ +F AGTDTS ++E+A+A L++N L+T+ Q E+ I + + + +E D Sbjct: 295 NTDNIKALLLNLFTAGTDTSSSIIEWALAELLKNRTLLTRAQDEMDRVIGRDRRL-LESD 353 Query: 373 LNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCV-INGYTIPSGTRVIVNSRAIARDPSS 549 + +L YL+A+ KET R H PL +P + V +NGY IP GTR+ VN AI RDPS Sbjct: 354 IPNLPYLQAICKETFRKHPSTPLNLPRNCIRGHVDVNGYYIPKGTRLNVNIWAIGRDPSV 413 Query: 550 W 552 W Sbjct: 414 W 414
>C93A2_SOYBN (Q42799) Cytochrome P450 93A2 (EC 1.14.-.-)| Length = 502 Score = 105 bits (261), Expect = 1e-22 Identities = 64/178 (35%), Positives = 101/178 (56%), Gaps = 9/178 (5%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHE-----SKPAPALGDDTDYIHDLLSI----QKEYNLTREQ 204 R R+ +D +L+ +I + E +K D + LL I E LT+E Sbjct: 229 RIRKTRIRFDAVLDRIIKQREEERRNNKEIGGTRQFKDILDVLLDIGEDDSSEIKLTKEN 288 Query: 205 VKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHL 384 +KA ++ +F AGTDTS ME+AMA L+ NP ++ K + E+ ++ ++ E D+ +L Sbjct: 289 IKAFIMDIFVAGTDTSAATMEWAMAELINNPCVLEKARQEI-DAVVGNSRIIEESDIVNL 347 Query: 385 AYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 YL+A+++ETLR+H PL+V + V+ GY IP+ TR+ VN AI RDP+ WE+ Sbjct: 348 PYLQAIVRETLRIHPGGPLIVRE-SSKSVVVCGYEIPAKTRLFVNVWAIGRDPNHWEN 404
>C71BZ_ARATH (Q9LXM3) Cytochrome P450 71B38 (EC 1.14.-.-)| Length = 500 Score = 104 bits (260), Expect = 1e-22 Identities = 61/180 (33%), Positives = 97/180 (53%), Gaps = 9/180 (5%) Frame = +1 Query: 43 VCGRARRVNKMWDDLL---ESLIHEHESKPAPALGDDTDYIHDLLSIQKE------YNLT 195 + G+ RVNK + L + +I +H P D +D + +L + + + +T Sbjct: 230 ISGQHSRVNKAFYKLTNFYKHVIDDHLKTGQPQ--DHSDIVSVMLDMINKPTKADSFKVT 287 Query: 196 REQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDL 375 + +K + +F AG + M + + L ++P +M KLQ E+R+ + K + E+DL Sbjct: 288 YDHLKGVMSDIFLAGVNGGANTMIWTLTELSRHPRVMKKLQEEIRAMLGPNKERITEEDL 347 Query: 376 NHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 + YLK V+ ET RLH PAPLL+P L M+D I GY IP T + +N+ AI RDP W+ Sbjct: 348 EKVEYLKLVMVETFRLHPPAPLLLPRLTMSDIKIQGYNIPKNTMIQINTYAIGRDPKYWK 407
>C71BF_ARATH (Q9LW27) Cytochrome P450 71B15 (EC 1.14.-.-)| Length = 490 Score = 104 bits (260), Expect = 1e-22 Identities = 60/180 (33%), Positives = 98/180 (54%), Gaps = 7/180 (3%) Frame = +1 Query: 43 VCGRARRVNKMW---DDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTRE 201 + G+ RR+ + D +++++EH KP D + D+ Q+ T + Sbjct: 230 ISGQNRRLKNNFSVVDTFFQNVLNEH-LKPGRESSTIVDLMIDMKKKQENDGDALKFTTD 288 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 +K + +F AG + + M L++NP +M K+Q E+R+++ K + E+DLN Sbjct: 289 HLKGMISDIFVAGIGGVAGITLWGMTELIRNPRVMKKVQDEIRTTLGDKKERIKEEDLNQ 348 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWESA 561 L Y K V+KETLRLH PLL+P M+ I GY +P+ T+++VN A+ RDP WE+A Sbjct: 349 LHYFKLVVKETLRLHPTTPLLLPRQTMSHIKIQGYDVPAKTQILVNVYAMGRDPKLWENA 408
>C71BT_ARATH (Q9SAE4) Cytochrome P450 71B29 (EC 1.14.-.-)| Length = 490 Score = 104 bits (259), Expect = 2e-22 Identities = 59/184 (32%), Positives = 103/184 (55%), Gaps = 10/184 (5%) Frame = +1 Query: 31 IRWMVCGRARRVNKMWDDL---LESLIHEHESKPAPALGDDTDYIHDLLSIQKE------ 183 I W + G+ +R + ++ DL ++++ H KP + D +D I ++++ K+ Sbjct: 224 IDW-ISGQNKRFDNVFSDLDTFFQNILDYH-LKPGRKVADSSDIIDVVINMIKKQEKDGD 281 Query: 184 -YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMV 360 + LT + +K + +F AG TS + +A+ L++N +M K+Q E+R+++ K + Sbjct: 282 SFKLTTDHLKGMISDIFLAGVSTSASTLIWAITELVRNRKVMKKVQEEIRTTLGDKKERI 341 Query: 361 IEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 E DL +L Y K V+KE RLH P L+P ++ I GY IP+ T++++N AIARD Sbjct: 342 TEQDLTNLHYFKLVVKEIFRLHPAVPFLLPRETLSHVKIQGYDIPAKTQIMINVYAIARD 401 Query: 541 PSSW 552 P W Sbjct: 402 PKLW 405
>C84A1_ARATH (Q42600) Cytochrome P450 84A1 (EC 1.14.-.-)| (Ferulate-5-hydroxylase) (F5H) Length = 520 Score = 102 bits (255), Expect = 6e-22 Identities = 63/175 (36%), Positives = 103/175 (58%), Gaps = 17/175 (9%) Frame = +1 Query: 79 DDLLESLIHEHESKPAPALGD--DTDYIHDLLS--------------IQKEYNLTREQVK 210 DD+++ + + E++ A GD DTD + DLL+ +Q LTR+ +K Sbjct: 251 DDIIDEHMKKKENQNAVDDGDVVDTDMVDDLLAFYSEEAKLVSETADLQNSIKLTRDNIK 310 Query: 211 AQLV-IMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLA 387 A ++ +MFG GT+T +E+A+ L+++P+ + ++Q E+ + + V E D+ L Sbjct: 311 AIIMDVMFG-GTETVASAIEWALTELLRSPEDLKRVQQELAEVVGLDRR-VEESDIEKLT 368 Query: 388 YLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 YLK +KETLR+H P PLL+ H D I+G+ IP +RV++N+ AI RDP+SW Sbjct: 369 YLKCTLKETLRMHPPIPLLL-HETAEDTSIDGFFIPKKSRVMINAFAIGRDPTSW 422
>C71B2_ARATH (O65788) Cytochrome P450 71B2 (EC 1.14.-.-)| Length = 502 Score = 102 bits (255), Expect = 6e-22 Identities = 57/173 (32%), Positives = 95/173 (54%), Gaps = 6/173 (3%) Frame = +1 Query: 52 RARRVNKMWDDL---LESLIHEHESKPAPALGDDTDYIHDLLSIQKE---YNLTREQVKA 213 R +++NK++ +L + +I +H D I D++ Q++ + L + +KA Sbjct: 237 RHKKINKVFKELDAFYQHVIDDHLKPEGRKNQDIVTLILDMIDKQEDSDSFKLNMDNLKA 296 Query: 214 QLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYL 393 ++ +F AG DTS + M +AM L++NP +M K Q +R+++ K + E+DL + YL Sbjct: 297 IVMDVFLAGIDTSAVTMIWAMTELIRNPRVMKKAQESIRTTLGLKKERITEEDLGKVEYL 356 Query: 394 KAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ++KET RLH P +VP M+ I GY IP T++ +N I RDP W Sbjct: 357 NHILKETFRLHPALPFVVPRETMSHIKIQGYDIPPKTQIQLNVWTIGRDPKRW 409
>C71BC_ARATH (Q9ZU07) Cytochrome P450 71B12 (EC 1.14.-.-)| Length = 496 Score = 102 bits (255), Expect = 6e-22 Identities = 58/125 (46%), Positives = 75/125 (60%) Frame = +1 Query: 181 EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMV 360 E+ LTR+ K L + AG DTS VM + M L+ NP ++ K QAEVR I K K + Sbjct: 279 EFQLTRDHTKGILANILNAGIDTSAQVMTWVMTYLISNPRVLKKAQAEVREVI-KHKDDI 337 Query: 361 IEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 IE+D+ L YLK VIKET R++ PLL+P A D I GY IP T + VN AI R+ Sbjct: 338 IEEDIERLQYLKMVIKETFRINPLVPLLIPREASKDVKIGGYNIPKKTWIHVNIWAIHRN 397 Query: 541 PSSWE 555 P+ W+ Sbjct: 398 PNVWK 402
>C75A6_CAMME (O04773) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A6) Length = 523 Score = 102 bits (255), Expect = 6e-22 Identities = 62/184 (33%), Positives = 102/184 (55%), Gaps = 8/184 (4%) Frame = +1 Query: 31 IRWMVCGRARR----VNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----Y 186 I WM +R + K +D LL +I EH ++ A D+ D++ L++ +E Sbjct: 243 IAWMDLQGIQRDMKVIQKKFDVLLNKMIKEH-TESAHDRKDNPDFLDILMAATQENTEGI 301 Query: 187 NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIE 366 L VKA L+ +F AGTDTS V+E+A+A ++ + ++ + E+ I + + + + Sbjct: 302 QLNLVNVKALLLDLFTAGTDTSSSVIEWALAEMLNHRQILNRAHEEMDQVIGRNRRLE-Q 360 Query: 367 DDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPS 546 D+ +L Y +A+ KET R H PL +P ++ C ++G+ IP TR+IVN AI RDP Sbjct: 361 SDIPNLPYFQAICKETFRKHPSTPLNLPRISTEACEVDGFHIPKNTRLIVNIWAIGRDPK 420 Query: 547 SWES 558 WE+ Sbjct: 421 VWEN 424
>C76C3_ARATH (O64638) Cytochrome P450 76C3 (EC 1.14.-.-)| Length = 515 Score = 102 bits (254), Expect = 7e-22 Identities = 64/151 (42%), Positives = 90/151 (59%) Frame = +1 Query: 106 EHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARL 285 E E K A ++ D D + DL Q E LT +K L+ +F AGTDT+ ME+AM L Sbjct: 272 EKEPKEASSI-DMLDSLLDLTQ-QNEAELTMNDLKHLLLDVFVAGTDTNSSTMEWAMTEL 329 Query: 286 MQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMA 465 ++ + M K Q+E+R I + V E D+ L YL+A++KETLRLH AP L+P + + Sbjct: 330 FRSTEKMVKAQSEIRQVIGQ-NGFVQESDIPSLPYLQAIVKETLRLHPAAP-LIPRKSES 387 Query: 466 DCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 D I G+ +P T+V+VN AI RD S WE+ Sbjct: 388 DVQIMGFLVPKNTQVVVNVWAIGRDASVWEN 418
>C76A1_SOLME (P37121) Cytochrome P450 76A1 (EC 1.14.-.-) (CYPLXXVIA1) (P-450EG8)| (Fragment) Length = 467 Score = 102 bits (253), Expect = 1e-21 Identities = 60/179 (33%), Positives = 99/179 (55%), Gaps = 9/179 (5%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN---------LTRE 201 G+ + + K + +E I E + G+ I DLL + ++ L+ + Sbjct: 209 GKGKEITKKF---IEERIEERKK------GEKNRSIKDLLDVLIDFEGSGKDEPDKLSED 259 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 ++ ++ MF AGT+T+ +E+A+ L+++P M K++ E+ I K E D++ Sbjct: 260 EITVIILEMFLAGTETTSSSVEWALTELLRHPQAMAKVKLEILQVIGPNKKFE-ECDIDS 318 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 L Y++AV+KE LRLH P PLL+P A+ D GY IP GT+V+VN+ AI RDP W++ Sbjct: 319 LPYMQAVLKEQLRLHPPLPLLIPRKAIQDTKFMGYDIPKGTQVLVNAWAIGRDPEYWDN 377
>C71BB_ARATH (P58049) Cytochrome P450 71B11 (EC 1.14.-.-)| Length = 496 Score = 102 bits (253), Expect = 1e-21 Identities = 68/177 (38%), Positives = 93/177 (52%), Gaps = 9/177 (5%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDT---DYIHDLLSIQK------EYNLTREQ 204 + ++ K D + I H L D++ D I LL +++ E+ LTR+ Sbjct: 234 KCEKIFKAMDAFFDQSIKHH-------LEDESIKDDIIDLLLKMERGEIELGEFQLTRDN 286 Query: 205 VKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHL 384 K L + AG DTS VM + M L+ NP +M K QAEVR I K K +IE+D+ L Sbjct: 287 TKGILFNILNAGIDTSAQVMTWVMTYLISNPRVMKKAQAEVREVI-KNKDDIIEEDIERL 345 Query: 385 AYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 YLK V+KET R+ PLL+P A D I GY IP T + VN AI R+P+ W+ Sbjct: 346 EYLKMVVKETFRVLPLVPLLIPREASKDVKIGGYDIPKKTWIHVNIWAIHRNPNVWK 402
>C93A3_SOYBN (O81973) Cytochrome P450 93A3 (EC 1.14.-.-) (P450 CP5)| Length = 510 Score = 101 bits (252), Expect = 1e-21 Identities = 61/178 (34%), Positives = 100/178 (56%), Gaps = 9/178 (5%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPA--------LGDDTDYIHDLLSIQK-EYNLTREQ 204 R ++ +D +L+ +I + E + D D + D+ + E L +E Sbjct: 237 RLEKIRDCFDTVLDRIIKQREEERRNKNETVGKREFKDMLDVLFDISEDESSEIKLNKEN 296 Query: 205 VKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHL 384 +KA ++ + AGTDTS + ME+AMA L+ NP ++ K + E+ + + K + +V E D+ +L Sbjct: 297 IKAFILDILIAGTDTSAVTMEWAMAELINNPGVLEKARQEMDAVVGKSR-IVEESDIANL 355 Query: 385 AYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 YL+ +++ETLRLH PLL + V+ GY IP+ TR+ VN AI RDP+ WE+ Sbjct: 356 PYLQGIVRETLRLHPAGPLLFRE-SSRRAVVCGYDIPAKTRLFVNVWAIGRDPNHWEN 412
>C76A2_SOLME (P37122) Cytochrome P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7)| Length = 505 Score = 101 bits (251), Expect = 2e-21 Identities = 59/189 (31%), Positives = 104/189 (55%), Gaps = 5/189 (2%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQ-- 177 FP L K D+ + + AR + K + ++ + E E + D++ LL Q Sbjct: 229 FPFLKKFDL-QSLRKKMARDMGKAVE-IMSMFLKEREEERKKGTEKGKDFLDVLLEFQGT 286 Query: 178 ---KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKG 348 + L+ ++K ++ MF AGT+T+ +E+A+ L+++P+ M K++ E+ +I Sbjct: 287 GKDEPAKLSEHEIKIFVLEMFLAGTETTSSSVEWALTELLRHPEAMAKVKTEISQAIEPN 346 Query: 349 KHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRA 528 + + D+ +L Y++AV+KE+LRLH P P L+P + D GY +P T+V+VN+ A Sbjct: 347 RKFE-DSDIENLPYMQAVLKESLRLHPPLPFLIPRETIQDTKFMGYDVPKDTQVLVNAWA 405 Query: 529 IARDPSSWE 555 I RDP W+ Sbjct: 406 IGRDPECWD 414
>C71B1_THLAR (P49264) Cytochrome P450 71B1 (EC 1.14.-.-) (CYPLXXIB1)| Length = 496 Score = 100 bits (250), Expect = 2e-21 Identities = 63/165 (38%), Positives = 85/165 (51%), Gaps = 6/165 (3%) Frame = +1 Query: 79 DDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK------EYNLTREQVKAQLVIMFGAG 240 D + I H P+ D I LL +++ EY LTRE K L+ + AG Sbjct: 243 DSFFDQAIQRHIDDPSIK----DDIIDLLLKMERGEGSLGEYELTREHTKGILMNILTAG 298 Query: 241 TDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLR 420 DTS M +AM L+ NP +M KLQAE+R I K + +DD+ L Y K V+KET R Sbjct: 299 IDTSAQTMTWAMTHLLANPRVMKKLQAEIREKI-KNIDEITDDDVEQLDYFKLVLKETFR 357 Query: 421 LHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 + P+LVP +A D I GY +P T + VN A+ PS W+ Sbjct: 358 ISPIVPVLVPRVAAKDLKIAGYDVPEKTWIHVNMWAVHMSPSIWK 402
>C81F1_ARATH (O65790) Cytochrome P450 81F1 (EC 1.14.-.-)| Length = 500 Score = 100 bits (249), Expect = 3e-21 Identities = 58/168 (34%), Positives = 95/168 (56%), Gaps = 2/168 (1%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN--LTREQVKAQLVIMF 231 + + K DD+L+ L+ E + ++ L+S+Q++ T +K ++ M Sbjct: 244 KAIGKSMDDILQRLLDECRRDK-----EGNTMVNHLISLQQQQPEYYTDVIIKGLMMSMM 298 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 AGT+TS + +E+AMA L++NP+++ K ++E+ I K + ++ E D+ L YL+ V+ E Sbjct: 299 LAGTETSAVTLEWAMANLLRNPEVLEKARSEIDEKIGKDR-LIDESDIAVLPYLQNVVSE 357 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 T RL AP L+P D I GY +P T V+VN+ AI RDP WE Sbjct: 358 TFRLFPVAPFLIPRSPTDDMKIGGYDVPRDTIVMVNAWAIHRDPEIWE 405
>C83A1_ARATH (P48421) Cytochrome P450 83A1 (EC 1.14.-.-) (CYPLXXXIII)| Length = 502 Score = 99.8 bits (247), Expect = 5e-21 Identities = 59/143 (41%), Positives = 85/143 (59%), Gaps = 6/143 (4%) Frame = +1 Query: 142 DTDYIHDLL-SIQKEY----NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLM 306 +T+ + DLL I KE T + VKA ++ + AGTDT+ + + M LM+ P ++ Sbjct: 264 ETESMIDLLMGIYKEQPFASEFTVDNVKAVILDIVVAGTDTAAAAVVWGMTYLMKYPQVL 323 Query: 307 TKLQAEVRSSIP-KGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVING 483 K QAEVR + KG V EDD+ +L Y +A++KETLR+ PLL+P + D I G Sbjct: 324 KKAQAEVREYMKEKGSTFVTEDDVKNLPYFRALVKETLRIEPVIPLLIPRACIQDTKIAG 383 Query: 484 YTIPSGTRVIVNSRAIARDPSSW 552 Y IP+GT V VN+ A++RD W Sbjct: 384 YDIPAGTTVNVNAWAVSRDEKEW 406
>C71BU_ARATH (Q9SCN2) Cytochrome P450 71B31 (EC 1.14.-.-)| Length = 498 Score = 99.8 bits (247), Expect = 5e-21 Identities = 54/170 (31%), Positives = 90/170 (52%), Gaps = 6/170 (3%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE------YNLTREQVKAQLV 222 ++ ++D+++ L+ + L D +D + +L + +T + + A + Sbjct: 243 KLTTFFEDVIDELLKTKQ------LDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMS 296 Query: 223 IMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 + AG + + M + M L ++P +M KLQ E+R+++ K + E+DL + YL V Sbjct: 297 DVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLV 356 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 IKE+ RLH PAPLL+P M+D I GY IP V +N+ AI RDP W Sbjct: 357 IKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRW 406
>C71BD_ARATH (P58050) Cytochrome P450 71B13 (EC 1.14.-.-)| Length = 496 Score = 99.4 bits (246), Expect = 6e-21 Identities = 64/174 (36%), Positives = 89/174 (51%), Gaps = 6/174 (3%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK------EYNLTREQVKA 213 + +V K D + I H G D + LL +++ E+ TR K Sbjct: 234 KCEKVFKGTDSFFDHCIKHHLEDG----GSKDDIVDLLLKVERGEIGLGEFQFTRNHTKG 289 Query: 214 QLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYL 393 L+ + AG DTS + + M L++NP +M K QAEVR I K K + E+D+ L YL Sbjct: 290 ILLDILLAGVDTSGHTITWVMTHLIKNPRVMKKAQAEVREVI-KNKDNITEEDIEGLEYL 348 Query: 394 KAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 K V+KETLR++ PLL P A D I GY IP T + VN AI R+P+ W+ Sbjct: 349 KMVVKETLRINPLVPLLTPREASKDVKIGGYNIPKKTWIHVNIWAIHRNPNVWK 402
>C78A3_SOYBN (O48927) Cytochrome P450 78A3 (EC 1.14.-.-)| Length = 523 Score = 99.0 bits (245), Expect = 8e-21 Identities = 59/169 (34%), Positives = 97/169 (57%), Gaps = 1/169 (0%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMF 231 R + M + + ++I EH + + D++ LLS+ + L+ + A L M Sbjct: 265 RCSNLVPMVNRFVGTIIAEHRASKTET---NRDFVDVLLSLPEPDQLSDSDMIAVLWEMI 321 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 GTDT +++E+ +AR+ +P + +K+Q E+ + + K + V EDD+ + YL AV+KE Sbjct: 322 FRGTDTVAVLIEWILARMALHPHVQSKVQEELDAVVGKAR-AVAEDDVAVMTYLPAVVKE 380 Query: 412 TLRLHMPAPLLV-PHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LRLH P PLL L++ D I+GY +P+GT +VN+ AI RDP W+ Sbjct: 381 VLRLHPPGPLLSWARLSINDTTIDGYHVPAGTTAMVNTWAICRDPHVWK 429
>C71B8_ARATH (P58048) Cytochrome P450 71B8 (EC 1.14.-.-)| Length = 506 Score = 98.2 bits (243), Expect = 1e-20 Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 11/181 (6%) Frame = +1 Query: 43 VCGRARRVNKMWDDLLESLIH--EHESKPAPALGDDTDYIH------DLLSIQKEYN--- 189 + G+ R+ K + L + H + E K +G D+ + D+++ EY Sbjct: 232 ISGQHSRIEKAFSKLTKFFQHVIDEELK----IGQSQDHSNLVSSMLDMINRSTEYGSFK 287 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 +T + + A + + G + I M + M L ++P +M KL+ E+R+++ K + E+ Sbjct: 288 ITSDHLIAMMTDIVLGGVNAGTITMIWTMTELTRHPRVMKKLREEIRATLGPNKERITEE 347 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 DL + YLK VIKET RLH P P L+P M+D I GY IP + +++ AI RDP Sbjct: 348 DLEKVEYLKLVIKETFRLHPPGPFLLPRQVMSDIEIQGYHIPKNAHIKISTYAIGRDPKC 407 Query: 550 W 552 W Sbjct: 408 W 408
>C71BE_ARATH (P58051) Cytochrome P450 71B14 (EC 1.14.-.-)| Length = 496 Score = 98.2 bits (243), Expect = 1e-20 Identities = 60/142 (42%), Positives = 81/142 (57%), Gaps = 6/142 (4%) Frame = +1 Query: 148 DYIHDLLSIQK------EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMT 309 D I LL ++K E+ LTR K L+ + AG DTS + + M L++NP +M Sbjct: 262 DIIGLLLKMEKGETGLGEFQLTRNHTKGILLNVLIAGVDTSGHTVTWVMTHLIKNPRVMK 321 Query: 310 KLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYT 489 K QAEVR I K K + E+D+ L YLK VIKETLR++ PLL+P A I GY Sbjct: 322 KAQAEVREVI-KNKDDITEEDIERLEYLKMVIKETLRINPLVPLLIPREASKYIKIGGYD 380 Query: 490 IPSGTRVIVNSRAIARDPSSWE 555 IP T + VN A+ R+P+ W+ Sbjct: 381 IPKKTWIYVNIWAVQRNPNVWK 402
>C83B1_ARATH (O65782) Cytochrome P450 83B1 (EC 1.14.-.-)| Length = 499 Score = 98.2 bits (243), Expect = 1e-20 Identities = 65/171 (38%), Positives = 97/171 (56%), Gaps = 4/171 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEY----NLTREQVKAQL 219 R ++ K D L+ L+ E P ++ +I L+ I K+ T E VKA + Sbjct: 235 RLKKAFKELDTYLQELLDETLDPNRPKQETES-FIDLLMQIYKDQPFSIKFTHENVKAMI 293 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + + GTDT+ V+ +AM L++ P+ M K Q EVRS I K V E+D+ +L YLKA Sbjct: 294 LDIVVPGTDTAAAVVVWAMTYLIKYPEAMKKAQDEVRSVIGD-KGYVSEEDIPNLPYLKA 352 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 VIKE+LRL P+L+ +AD I GY IP+ T + VN+ A++RD ++W Sbjct: 353 VIKESLRLEPVIPILLHRETIADAKIGGYDIPAKTIIQVNAWAVSRDTAAW 403
>C79A1_SORBI (Q43135) Cytochrome P450 79A1 (EC 1.14.13.41) (Tyrosine| N-monooxygenase) (Cytochrome P450Tyr) Length = 557 Score = 98.2 bits (243), Expect = 1e-20 Identities = 55/164 (33%), Positives = 90/164 (54%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGT 243 VN++ D +++ + +S + D D + L Q LT E+VKAQ + A Sbjct: 293 VNRLHDTVIDDRWRQWKSGERQEMEDFLDVLITLKDAQGNPLLTIEEVKAQSQDITFAAV 352 Query: 244 DTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRL 423 D +E+A+A ++ NP++M K E+ + + + +V E D+ L Y+KA I+E RL Sbjct: 353 DNPSNAVEWALAEMVNNPEVMAKAMEELDRVVGR-ERLVQESDIPKLNYVKACIREAFRL 411 Query: 424 HMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 H AP VPH+A+AD I GY +P G+ VI++ + R+P W+ Sbjct: 412 HPVAPFNVPHVALADTTIAGYRVPKGSHVILSRTGLGRNPRVWD 455
>C82A1_PEA (Q43068) Cytochrome P450 82A1 (EC 1.14.-.-) (CYPLXXXII) (Fragment)| Length = 544 Score = 96.7 bits (239), Expect = 4e-20 Identities = 62/186 (33%), Positives = 97/186 (52%), Gaps = 12/186 (6%) Frame = +1 Query: 31 IRWMVCG----RARRVNKMWDDLLESLIHEHESKPAPALGD----DTDYIHDLLSIQKEY 186 ++W+ G ++ K +D +L + EH K D + D++ +L + K+ Sbjct: 260 LKWLDLGGHEKEMKKCAKKFDVMLNEWLEEHREKKGLGSEDKVVGERDFMDAMLLVLKDK 319 Query: 187 NLTREQV----KAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 + V KA + + G+DT+ + +AM L+++P ++ KL+ E+ + I K + Sbjct: 320 PIEGFDVDTIIKATTLELILGGSDTTAGTLTWAMCLLLKHPHVLEKLKEELNTYIGK-ER 378 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 V E D+N L YL A+IKETLRL+ PAP P DC I GY I GTR++ N I Sbjct: 379 CVNESDINKLVYLHAIIKETLRLYPPAPFSSPREFTEDCTIGGYHIKKGTRLMPNLWKIH 438 Query: 535 RDPSSW 552 RDPS W Sbjct: 439 RDPSVW 444
>C71DB_LOTJA (O22307) Cytochrome P450 71D11 (EC 1.14.-.-) (Fragment)| Length = 490 Score = 95.9 bits (237), Expect = 7e-20 Identities = 64/172 (37%), Positives = 96/172 (55%), Gaps = 9/172 (5%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHES----KPAPALGDDTDYIHDLL-----SIQKEYNLTREQVKAQ 216 +++ D +LE++I +H++ K G + D I LL S ++++LT +KA Sbjct: 223 LHQKMDRILETIIDDHKANSRTKEGQVEGGEEDLIDVLLKYENSSTDQDFHLTIRNIKAI 282 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 L +F AG++TS + + MA +M++P L+ K Q EVR I + + V E + L YLK Sbjct: 283 LFDIFIAGSETSATTINWTMAEMMKDPILLKKAQDEVR-EIFQRRGKVDETCIYELKYLK 341 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 A I E LRLH P PL+ A C INGY IP+ + V+VN+ AI D W Sbjct: 342 AFINEVLRLHPPGPLVFRECRQA-CEINGYHIPAKSTVLVNTFAIGTDSKYW 392
>C99A1_SORBI (O48957) Cytochrome P450 CYP99A1 (EC 1.14.-.-) (Fragment)| Length = 519 Score = 95.9 bits (237), Expect = 7e-20 Identities = 59/192 (30%), Positives = 98/192 (51%), Gaps = 9/192 (4%) Frame = +1 Query: 4 FPELLKLDIIRWM---VCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSI 174 FP L +D++ + + RR++ ++D +L E + + D ++ LL I Sbjct: 222 FPSLWFVDVVTGLTRRLWTARRRLDAIFDRILAEC--EARQRQEEKMTGDDGFLGVLLRI 279 Query: 175 QKEYN------LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSS 336 + + ++ +KA L M GT+T+ E+ M+ LM+ P+ M K QAEVR + Sbjct: 280 RDDDGEPETGGISTTSIKAILFDMLAGGTETTSSAAEWIMSELMRKPEAMAKAQAEVRGA 339 Query: 337 IPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIV 516 + E ++ L+Y + V+KE LRLH PLL+P C + G+ + GT+VIV Sbjct: 340 LDGKSPEDHEGQMDKLSYTRMVVKEGLRLHPVLPLLLPRSCQETCDVGGFEVTKGTKVIV 399 Query: 517 NSRAIARDPSSW 552 N+ A+AR P W Sbjct: 400 NAWALARSPERW 411
>C82A2_SOYBN (O81972) Cytochrome P450 82A2 (EC 1.14.-.-) (P450 CP4)| Length = 522 Score = 95.5 bits (236), Expect = 9e-20 Identities = 61/185 (32%), Positives = 99/185 (53%), Gaps = 9/185 (4%) Frame = +1 Query: 31 IRWMVCGR----ARRVNKMWDDLLESLIHEHESKPAPALGDDT-DYIHDLLSIQKEYNLT 195 +RW G R K D+++ + EH K +G++ D + LLS+ + + Sbjct: 243 LRWFDFGGYENDMRETGKELDEIIGEWLDEHRQKRK--MGENVQDLMSVLLSLLEGKTIE 300 Query: 196 REQV----KAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVI 363 V K+ ++ + AGT+ S + +A + ++ NP ++ KL+AE+ + K ++ + Sbjct: 301 GMNVDIVIKSFVLTVIQAGTEASITTLIWATSLILNNPSVLEKLKAELDIQVGKERY-IC 359 Query: 364 EDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDP 543 E DL+ L YL+AV+KETLRL+ PAPL P DC I GYT+ GTR+I N I D Sbjct: 360 ESDLSKLTYLQAVVKETLRLYPPAPLSRPREFEEDCTIGGYTVKKGTRLITNLSKIHTDH 419 Query: 544 SSWES 558 + W + Sbjct: 420 NVWSN 424
>C71A3_SOLME (P37119) Cytochrome P450 71A3 (EC 1.14.-.-) (CYPLXXIA3) (P-450EG3)| (Fragment) Length = 365 Score = 95.5 bits (236), Expect = 9e-20 Identities = 61/137 (44%), Positives = 82/137 (59%), Gaps = 7/137 (5%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEH---ESKPAPALGDDTDYIHDLLSIQ--KE--YNLTREQVKAQL 219 +V K D LE +I H K G+ D + LL IQ KE + + R+ +KA L Sbjct: 230 KVAKDLDTFLEFVIEAHMIRNEKEENRAGESKDLVDVLLEIQNGKETGFPIQRDSLKALL 289 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + F AGTDT Y V+E+ M L+++P M KLQ EV+ + + K + EDDL ++ YLKA Sbjct: 290 LDPFSAGTDTIYTVLEWTMTELLRHPRAMEKLQNEVQG-LAQEKAEITEDDLPNMHYLKA 348 Query: 400 VIKETLRLHMPAPLLVP 450 VIKETLRLH P PLL+P Sbjct: 349 VIKETLRLHPPIPLLLP 365
>C78AB_ORYSA (Q7Y1V5) Cytochrome P450 78A11 (EC 1.14.-.-) (PLASTOCHRON1 protein)| Length = 555 Score = 95.1 bits (235), Expect = 1e-19 Identities = 56/152 (36%), Positives = 85/152 (55%), Gaps = 2/152 (1%) Frame = +1 Query: 103 HEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMAR 282 H + D+ D++ LLS++ NL + + A L M GTDT+ +V E+ MA Sbjct: 306 HRLRRDSSSTAADNADFVDVLLSLEAHENLAEDDMVAVLWEMIFRGTDTTALVTEWCMAE 365 Query: 283 LMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLV-PHLA 459 +++NP + +L+AEV +++ G + D+ + YL+AV+KETLR H P PLL LA Sbjct: 366 VVRNPAVQARLRAEVDAAV-GGDGCPSDGDVARMPYLQAVVKETLRAHPPGPLLSWARLA 424 Query: 460 MADC-VINGYTIPSGTRVIVNSRAIARDPSSW 552 AD + NG +P+GT +VN AI D W Sbjct: 425 TADVGLANGMVVPAGTTAMVNMWAITHDGEVW 456
>C78A4_PINRA (O65012) Cytochrome P450 78A4 (EC 1.14.-.-)| Length = 553 Score = 95.1 bits (235), Expect = 1e-19 Identities = 64/187 (34%), Positives = 101/187 (54%), Gaps = 3/187 (1%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHE-SKPAPALGDDTDYIHDLLSIQKE 183 P L LD +R + R R+ + ++I +H + GD D++ LLS+Q E Sbjct: 271 PWLRPLDPLR--IHARCARLVPRVTTFVSNIIEQHRREEQRRESGDQCDFVDVLLSLQGE 328 Query: 184 YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVI 363 L E + A L M GTDT+ ++ E+ MA L+ +P+ K QAE+ + + + V Sbjct: 329 DKLDEEDMIAVLWEMIFRGTDTTALLTEWTMAELVLHPEAQKKAQAELDAVVGHDR-SVK 387 Query: 364 EDDLNHLAYLKAVIKETLRLHMPAPLLV-PHLAMADCVI-NGYTIPSGTRVIVNSRAIAR 537 + D+ L Y++AV+KE LR+H P PLL L+ D + +G +P+GT +VN +I Sbjct: 388 DSDIPKLPYIQAVVKEALRMHPPGPLLSWARLSTEDVNMGDGMCVPAGTTAMVNMWSITH 447 Query: 538 DPSSWES 558 DP+ WES Sbjct: 448 DPNIWES 454
>C71BR_ARATH (Q9SAE1) Cytochrome P450 71B27 (EC 1.14.-.-)| Length = 503 Score = 94.4 bits (233), Expect = 2e-19 Identities = 58/170 (34%), Positives = 90/170 (52%), Gaps = 6/170 (3%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK------EYNLTREQVKAQLV 222 +V++ D + +I +H KP+ L D + +L + K ++ L + +KA L+ Sbjct: 243 KVSEKLDAFYQHVIDDH-LKPS-TLDSSGDIVALMLDMIKKKGHKDDFKLNVDNIKAVLM 300 Query: 223 IMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 +F AG DT I M +AM L++ P +M + Q +R + + + E+DL LK + Sbjct: 301 NIFLAGIDTGAITMIWAMTELVKKPLVMKRAQENIRGVLGLKRDRITEEDLCKFDCLKHI 360 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 +KETLRLH P P LVP ++ I GY IP T++ VN I RDP W Sbjct: 361 VKETLRLHPPVPFLVPRETISHIKIQGYDIPPKTQIQVNVWTIGRDPKRW 410
>C79A2_ARATH (Q9FLC8) Cytochrome P450 79A2 (EC 1.-.-.-)| Length = 529 Score = 94.0 bits (232), Expect = 3e-19 Identities = 53/172 (30%), Positives = 88/172 (51%) Frame = +1 Query: 40 MVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQL 219 +V R V+K D ++ + + + D D + L+ E++KAQ+ Sbjct: 261 VVSNAMRNVSKYNDPFVDERLMQWRNGKMKEPQDFLDMFIIAKDTDGKPTLSDEEIKAQV 320 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 + A D E+ MA ++ P +M K E+ + K + +VIE DL +L Y+KA Sbjct: 321 TELMLATVDNPSNAAEWGMAEMINEPSIMQKAVEEIDRVVGKDR-LVIESDLPNLNYVKA 379 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 +KE RLH AP +PH++ D V++GY IP G+ V+++ I R+PS W+ Sbjct: 380 CVKEAFRLHPVAPFNLPHMSTTDTVVDGYFIPKGSHVLISRMGIGRNPSVWD 431
>C78A1_MAIZE (P48420) Cytochrome P450 78A1 (EC 1.14.-.-) (CYPLXXVIII)| Length = 547 Score = 93.6 bits (231), Expect = 3e-19 Identities = 55/152 (36%), Positives = 89/152 (58%), Gaps = 2/152 (1%) Frame = +1 Query: 103 HEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMAR 282 H + + AL D+ D++ LLS++ + L + + A L M GTDT+ ++ E+ MA Sbjct: 301 HRRRRQNSAALNDNADFVDVLLSLEGDEKLGDDDMVAILWEMVFRGTDTTALLTEWCMAE 360 Query: 283 LMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLV-PHLA 459 L+++P + +++AEV +++ G + D+ + YL+AV+KETLR H P PLL LA Sbjct: 361 LVRHPAVQARVRAEVDAAVGAG-GCPTDADVARMPYLQAVVKETLRAHPPGPLLSWARLA 419 Query: 460 MADC-VINGYTIPSGTRVIVNSRAIARDPSSW 552 AD + NG +P+GT +VN AI D + W Sbjct: 420 TADVPLCNGMVVPAGTTAMVNMWAITHDAAVW 451
>C82A3_SOYBN (O49858) Cytochrome P450 82A3 (EC 1.14.-.-) (P450 CP6)| Length = 527 Score = 93.2 bits (230), Expect = 4e-19 Identities = 61/187 (32%), Positives = 99/187 (52%), Gaps = 13/187 (6%) Frame = +1 Query: 31 IRWMVCG---RARRVN-KMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTR 198 +RW+ G +A + N K D LL + EH K LG++ + D + + L Sbjct: 245 LRWLDLGGHEKAMKANAKEVDKLLSEWLEEHRQKKL--LGENVESDRDFMDVMISA-LNG 301 Query: 199 EQV---------KAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGK 351 Q+ KA + + GTD++ + + +A++ L++NP + K + E+ I K + Sbjct: 302 AQIGAFDADTICKATSLELILGGTDSTAVTLTWALSLLLRNPLALGKAKEEIDMQIGKDE 361 Query: 352 HMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAI 531 + + E D++ L YL+A++KETLRL+ PAP P +C++ GY I GTR+I N I Sbjct: 362 Y-IRESDISKLVYLQAIVKETLRLYPPAPFSSPREFTENCILGGYHIKKGTRLIHNLWKI 420 Query: 532 ARDPSSW 552 RDPS W Sbjct: 421 HRDPSVW 427
>C93B1_GLYEC (P93149) Cytochrome P450 93B1 (EC 1.14.13.87) (Licodione synthase)| ((2S)-flavanone 2-hydroxylase) (Flavone synthase II) (CYP GE-5) Length = 523 Score = 92.0 bits (227), Expect = 1e-18 Identities = 56/176 (31%), Positives = 96/176 (54%), Gaps = 15/176 (8%) Frame = +1 Query: 76 WDDLLESLIHEHES----------KPAPALGDDT-DYIHDLLSIQKEYN----LTREQVK 210 +D L+E +I + E K GD D++ LL ++ N + R +K Sbjct: 236 FDTLVERIISKREQTRKDRRRNGKKGEQGSGDGIRDFLDILLDCTEDENSEIKIQRVHIK 295 Query: 211 AQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAY 390 A ++ F AGTDT+ I E+A+ L++ P ++ K++ E+ + + K + +V E D +L Y Sbjct: 296 ALIMDFFTAGTDTTAISTEWALVELVKKPSVLQKVREEIDNVVGKDR-LVEESDCPNLPY 354 Query: 391 LKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 L+A++KET RLH P P +V +A+C + Y IP + + VN +I R+P W++ Sbjct: 355 LQAILKETFRLHPPVP-MVTRRCVAECTVENYVIPEDSLLFVNVWSIGRNPKFWDN 409
>C71AR_ARATH (O65438) Cytochrome P450 71A27 (EC 1.14.-.-)| Length = 499 Score = 91.7 bits (226), Expect = 1e-18 Identities = 60/171 (35%), Positives = 91/171 (53%), Gaps = 4/171 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKE----YNLTREQVKAQL 219 + + +N D L+S++ EH + +D+I LL IQK+ + R + L Sbjct: 237 KMKDINNKLDCFLDSMVQEHVDADHK---EPSDFIDMLLLIQKDKTKRFKFDRSDLILIL 293 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 MF +GT T+ +E+ M LM++P+ M KLQ E+ S + V E ++ + YL Sbjct: 294 KDMFFSGTATTASQLEWTMTELMRHPECMKKLQDEINSFSTHNLN-VTEKEVEKMNYLHC 352 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 VIKE LRLH PLL L D + GY I +GT VI+N+ A+ R+P+ W Sbjct: 353 VIKEGLRLHPSGPLLF-RLPSEDVQLKGYDISAGTHVIINAWALQRNPAIW 402
>TCMO_GLYEC (Q96423) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 91.3 bits (225), Expect = 2e-18 Identities = 47/134 (35%), Positives = 82/134 (61%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L QK+ + + V + + A +T+ +E+ +A L+ +P++ K++ E+ Sbjct: 279 IDHILDAQKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKVRDEIDR 338 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H V E D+ L YL+AVIKETLRL M PLLVPH+ + D + GY IP+ ++++ Sbjct: 339 VLGPG-HQVTEPDMQKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKIL 397 Query: 514 VNSRAIARDPSSWE 555 VN+ +A +P++W+ Sbjct: 398 VNAWWLANNPANWK 411
>TCMO_SOYBN (Q42797) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 506 Score = 90.1 bits (222), Expect = 4e-18 Identities = 46/134 (34%), Positives = 81/134 (60%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L Q++ + + V + + A +T+ +E+ +A L+ +P++ KL+ E+ Sbjct: 280 IDHILDAQRKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLRDEIDR 339 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H V E D+ L YL+AV+KETLRL M PLLVPH+ + D + GY IP+ ++++ Sbjct: 340 VLGAG-HQVTEPDIQKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKIL 398 Query: 514 VNSRAIARDPSSWE 555 VN+ +A +P+ W+ Sbjct: 399 VNAWWLANNPAHWK 412
>TCMO_ZINEL (Q43240) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 89.7 bits (221), Expect = 5e-18 Identities = 45/107 (42%), Positives = 71/107 (66%) Frame = +1 Query: 235 AGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKET 414 A +T+ +E+A+A L+ +P++ KL+ E+ S + G V E DL+ L YL+AVIKET Sbjct: 306 AAIETTLWSIEWAIAELVNHPEIQAKLRHELVSQLGPGVQ-VTEPDLHKLPYLQAVIKET 364 Query: 415 LRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LRL M PLLVPH+ + D + GY IP+ ++++VN+ +A +P W+ Sbjct: 365 LRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPDQWK 411
>TCMO_RUTGR (Q9AR74) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 506 Score = 89.4 bits (220), Expect = 6e-18 Identities = 47/134 (35%), Positives = 81/134 (60%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L Q++ + + V + + A +T+ +E+ +A L+ +PD+ KL+AE+ Sbjct: 279 IDHVLDAQQKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPDIQKKLRAEI-D 337 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + H + E D + L YL+AVIKETLRL M PLLVPH+ + D + GY IP+ ++++ Sbjct: 338 RVLGPDHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLAGYDIPAESKIL 397 Query: 514 VNSRAIARDPSSWE 555 VN+ +A +P+ W+ Sbjct: 398 VNAWWLANNPAHWK 411
>CP17A_ICTPU (O73853) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 514 Score = 89.4 bits (220), Expect = 6e-18 Identities = 44/127 (34%), Positives = 79/127 (62%) Frame = +1 Query: 178 KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 ++ LT + + + +FGAG +T+ V+++++ L+ +P + K+Q E+ + I + +H Sbjct: 286 QDVGLTDDHLLMTVGDIFGAGVETTTTVLKWSILYLIHHPQVQRKIQEELDAKIGRDRHP 345 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 + D N L YL+A I+E LR+ +PLL+PH+A++D I YT+ GTRVIVN ++ Sbjct: 346 QVNDRGN-LPYLEATIREVLRIRPVSPLLIPHVALSDANIGEYTVQKGTRVIVNLWSLHH 404 Query: 538 DPSSWES 558 D W++ Sbjct: 405 DEKEWKN 411
>TCMO_PHAAU (P37115) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 88.6 bits (218), Expect = 1e-17 Identities = 45/134 (33%), Positives = 81/134 (60%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L +K+ + + V + + A +T+ +E+ +A L+ +P++ K++ E+ Sbjct: 279 IDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKVRDEIDR 338 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H V E D+ L YL+AV+KETLRL M PLLVPH+ + D + GY IP+ ++++ Sbjct: 339 VLGVG-HQVTEPDIQKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKIL 397 Query: 514 VNSRAIARDPSSWE 555 VN+ +A +P+ W+ Sbjct: 398 VNAWWLANNPAHWK 411
>TCMO_ARATH (P92994) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 87.8 bits (216), Expect = 2e-17 Identities = 43/107 (40%), Positives = 73/107 (68%) Frame = +1 Query: 235 AGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKET 414 A +T+ +E+ +A L+ +P++ +KL+ E+ + + G V E DL+ L YL+AV+KET Sbjct: 306 AAIETTLWSIEWGIAELVNHPEIQSKLRNELDTVLGPGVQ-VTEPDLHKLPYLQAVVKET 364 Query: 415 LRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LRL M PLLVPH+ + D + GY IP+ ++++VN+ +A +P+SW+ Sbjct: 365 LRLRMAIPLLVPHMNLHDAKLAGYDIPAESKILVNAWWLANNPNSWK 411
>C82A4_SOYBN (O49859) Cytochrome P450 82A4 (EC 1.14.-.-) (P450 CP9)| Length = 525 Score = 87.8 bits (216), Expect = 2e-17 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 11/185 (5%) Frame = +1 Query: 31 IRWMVCGRARRVNKMWDDLLESLIHE--HESKPAPALGDDTDYIHDLLSIQKEYNLTREQ 204 +RW+ G + K L+ +I E E + ALG+ D D +++ +L + Sbjct: 244 LRWLDFGGYEKAMKETAKELDVMISEWLEEHRQKRALGEGVDGAQDFMNVMLS-SLDGKT 302 Query: 205 V---------KAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM 357 + K+ ++ + AGT+ S + +AM +++NP L+ + +AE+ + K + Sbjct: 303 IDGIDADTLIKSTVLTIIQAGTEASISTIIWAMCLILKNP-LILENKAELDIQVGKDR-C 360 Query: 358 VIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIAR 537 + E D+++L YL+AV+KETLRL+ P PL P DC + GY + GTR+I N I Sbjct: 361 ICESDISNLVYLQAVVKETLRLYAPGPLSSPREFAEDCTLGGYHVKKGTRLITNIWKIHT 420 Query: 538 DPSSW 552 DP+ W Sbjct: 421 DPNVW 425
>TCMO_POPTM (O24312) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 87.4 bits (215), Expect = 2e-17 Identities = 45/135 (33%), Positives = 81/135 (60%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L QK+ + + V + + A +T+ +E+ +A L+ +P++ KL+ E+ + Sbjct: 279 IDHILDAQKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRHELDT 338 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H + E D L YL AV+KETLRL M PLLVPH+ + D + G+ IP+ ++++ Sbjct: 339 LLGPG-HQITEPDTYKLPYLNAVVKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKIL 397 Query: 514 VNSRAIARDPSSWES 558 VN+ +A +P+ W++ Sbjct: 398 VNAWWLANNPAHWKN 412
>TCMO_POPKI (Q43054) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 87.4 bits (215), Expect = 2e-17 Identities = 45/135 (33%), Positives = 81/135 (60%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L QK+ + + V + + A +T+ +E+ +A L+ +P++ KL+ E+ + Sbjct: 279 IDHILDAQKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRHELDT 338 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H + E D L YL AV+KETLRL M PLLVPH+ + D + G+ IP+ ++++ Sbjct: 339 LLGPG-HQITEPDTYKLPYLNAVVKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKIL 397 Query: 514 VNSRAIARDPSSWES 558 VN+ +A +P+ W++ Sbjct: 398 VNAWWLANNPAHWKN 412
>TCMO_MEDSA (P37114) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 506 Score = 87.0 bits (214), Expect = 3e-17 Identities = 47/134 (35%), Positives = 81/134 (60%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L QK+ + + V + + A +T+ +E+ +A L+ + D+ K++ E+ Sbjct: 280 IDHILDAQKKGEINDDNVLYIVENINVAAIETTLWSIEWGIAELVNHQDIQNKVREEMDR 339 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H V E DL+ L YL+AVIKETLRL M PLLVPH+ + D +NG+ IP+ ++++ Sbjct: 340 VLGPG-HQVTEPDLHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDPKLNGFDIPAESKIL 398 Query: 514 VNSRAIARDPSSWE 555 VN+ + +P+ W+ Sbjct: 399 VNAWWLPNNPAHWK 412
>TCMO_PEA (Q43067) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 87.0 bits (214), Expect = 3e-17 Identities = 47/134 (35%), Positives = 80/134 (59%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L QK+ + + V + + A +T+ +E+ +A L+ + ++ KL+ E+ Sbjct: 279 IDHILDAQKKGEINDDNVLYIVENINVAAIETTLWSIEWGIAELVNHQEIQNKLREEMDK 338 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H V E DL L YL+AVIKETLRL M PLLVPH+ + D + G+ IP+ ++++ Sbjct: 339 VLGPG-HQVTEPDLEKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKIL 397 Query: 514 VNSRAIARDPSSWE 555 VN+ +A +P+ W+ Sbjct: 398 VNAWWLANNPALWK 411
>CP17A_RANDY (O57525) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 519 Score = 87.0 bits (214), Expect = 3e-17 Identities = 55/189 (29%), Positives = 96/189 (50%), Gaps = 12/189 (6%) Frame = +1 Query: 22 LDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLL----------- 168 LDI+R V R D LL+ I+EH+ G+ + D L Sbjct: 243 LDILRQSVAAR--------DQLLQKKINEHKDA---FCGETVKDLVDALLKAKLNMENNN 291 Query: 169 -SIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPK 345 ++ ++ LT + + + +FGAG +T+ V+++A+A L+ P++ K+Q E+ + Sbjct: 292 SNVSQDVGLTEDHILMTVGDIFGAGVETTSTVLKWAVAYLLHYPEVQKKIQEELDVKVGF 351 Query: 346 GKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSR 525 G++ ++ D L Y +A I E LR+ +PLL+PH+A+ + I YTIP RV++N Sbjct: 352 GRYPLLSDR-KILHYTEAAISEVLRIRPVSPLLIPHVALKESSIGEYTIPKEARVVINLW 410 Query: 526 AIARDPSSW 552 ++ D W Sbjct: 411 SLHHDEKEW 419
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 86.7 bits (213), Expect = 4e-17 Identities = 47/126 (37%), Positives = 73/126 (57%) Frame = +1 Query: 181 EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMV 360 E LT + + + +FGAG +TS + + L+ +P++ K+Q E+ S+I + Sbjct: 287 EAGLTDDHMVMTVADIFGAGVETSSTAFAWMIIYLIHHPEVQKKIQEEIDSNIGFERTPK 346 Query: 361 IEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 + D N + +L A I E LR+ +PLL+PH+A+AD I YTIP GTRVI+N AI D Sbjct: 347 MSDKGN-MNFLNATIHEILRIQPVSPLLIPHVALADSSIGDYTIPKGTRVIINLWAIHHD 405 Query: 541 PSSWES 558 W++ Sbjct: 406 EKEWKN 411
>CP17A_CHICK (P12394) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 85.1 bits (209), Expect = 1e-16 Identities = 53/177 (29%), Positives = 90/177 (50%), Gaps = 11/177 (6%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLL-----------SIQKEYNLTREQ 204 +R K+ D LL+ EH+ GD + D L ++ LT + Sbjct: 238 KRCLKVRDQLLQQKFTEHKEA---FCGDTVRDLMDALLQVRLNAENNSPLEPGLELTDDH 294 Query: 205 VKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHL 384 + + +FGAG +T+ V+++A+ L+ P++ K+Q E+ I +H + D L Sbjct: 295 LLMTVGDIFGAGVETTTTVLKWAVLYLLHYPEVQKKIQEEMDQKIGLARHPHLSDR-PLL 353 Query: 385 AYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 YL+A I E LR+ +PLL+PH+++AD I Y+IP G RV++N ++ D W+ Sbjct: 354 PYLEATISEGLRIRPVSPLLIPHVSLADTSIGEYSIPKGARVVINLWSVHHDEKEWD 410
>C89A2_ARATH (Q42602) Cytochrome P450 89A2 (EC 1.14.-.-) (CYPLXXXIX) (ATH 6-1)| Length = 506 Score = 84.7 bits (208), Expect = 2e-16 Identities = 58/196 (29%), Positives = 90/196 (45%), Gaps = 12/196 (6%) Frame = +1 Query: 4 FPELLKLDII-RWMVCGRARRVNKMWDDLLESLIHEH----ESKPAPALGDDTDYIH--- 159 +P+ KL + RW + RR + D+L LI E + D DY+ Sbjct: 220 WPKFTKLILRKRWQEFLQIRRQQR---DVLLPLIRARRKIVEERKRSEQEDKKDYVQSYV 276 Query: 160 ----DLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEV 327 DL ++ L E + AGTDT+ +++ MA L++ P++ +L E+ Sbjct: 277 DTLLDLELPEENRKLNEEDIMNLCSEFLTAGTDTTATALQWIMANLVKYPEIQERLHEEI 336 Query: 328 RSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTR 507 +S + + V E+D+ + YLKAV+ E LR H P L+PH D V+ GY +P Sbjct: 337 KSVVGEEAKEVEEEDVEKMPYLKAVVLEGLRRHPPGHFLLPHSVTEDTVLGGYKVPKNGT 396 Query: 508 VIVNSRAIARDPSSWE 555 + I RDP WE Sbjct: 397 INFMVAEIGRDPVEWE 412
>TCMO_CICAR (O81928) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 84.7 bits (208), Expect = 2e-16 Identities = 45/134 (33%), Positives = 80/134 (59%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L Q++ + + V + + A +T+ +E+ +A L+ + + K++ E+ Sbjct: 278 IDHILDAQQKGEINDDNVLYIVENINVAAIETTLWSIEWGIAELVNHQKIQNKVREEIDR 337 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G H V E DL L YL+AVIKETLRL M PLLVPH+ + D ++G+ IP+ ++++ Sbjct: 338 VLGPG-HQVTEPDLQKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLSGFDIPAESKIL 396 Query: 514 VNSRAIARDPSSWE 555 VN+ +A +P+ W+ Sbjct: 397 VNAWWLANNPAQWK 410
>CP2L1_PANAR (Q27712) Cytochrome P450 2L1 (EC 1.14.14.1) (CYPIIL1)| Length = 492 Score = 84.3 bits (207), Expect = 2e-16 Identities = 51/162 (31%), Positives = 89/162 (54%), Gaps = 4/162 (2%) Frame = +1 Query: 82 DLLESLIHEHESKPAPALGDDT--DYIHDLLSIQKE--YNLTREQVKAQLVIMFGAGTDT 249 D +++ I EH++ P+ D Y+ DL +++ + E V+A ++ +FGAGT+T Sbjct: 243 DYMKTFIKEHQATLDPSNPKDLLDAYLIDLQERKEDPLSTMNIETVRAVIMDLFGAGTET 302 Query: 250 SYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHM 429 + ++ + + LM+ P++ K+Q E+ +++P+G +E + LAY +A I E R+ Sbjct: 303 TSTMIRWTILYLMKYPEVQAKIQREIDAAVPRGTLPSLEHK-DKLAYFEATIHEVHRIVS 361 Query: 430 PAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 PL V H D + GY +P GT V+ + RDPS WE Sbjct: 362 LVPLGVSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYWE 403
>TCMO_HELTU (Q04468) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 84.3 bits (207), Expect = 2e-16 Identities = 39/107 (36%), Positives = 70/107 (65%) Frame = +1 Query: 235 AGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKET 414 A +T+ +E+ +A L+ +P++ KL+ E+ + + G + E D+ +L YL+AV+KET Sbjct: 306 AAIETTLWSIEWGIAELVNHPEIQAKLRHELDTKLGPGVQ-ITEPDVQNLPYLQAVVKET 364 Query: 415 LRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LRL M PLLVPH+ + D + G+ IP+ ++++VN+ +A +P W+ Sbjct: 365 LRLRMAIPLLVPHMNLHDAKLGGFDIPAESKILVNAWWLANNPDQWK 411
>C79B1_SINAL (O81345) Cytochrome P450 79B1 (EC 1.14.-.-)| Length = 542 Score = 84.0 bits (206), Expect = 3e-16 Identities = 42/138 (30%), Positives = 79/138 (57%), Gaps = 3/138 (2%) Frame = +1 Query: 148 DYIHDLLSIQKEYN---LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQ 318 D++ +SI+ E LT +++K + + A D +E+AMA ++ P+++ K Sbjct: 305 DFLDIFISIKDEEGNPLLTADEIKPTIKELVMAAPDNPSNAVEWAMAEMVNKPEILRKAM 364 Query: 319 AEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPS 498 E+ + K + +V E D+ L Y+KA+++E RLH A +PH+A++D + GY IP Sbjct: 365 EEIDRVVGK-ERLVQESDIPKLNYVKAILREAFRLHPVAAFNLPHVALSDATVAGYHIPK 423 Query: 499 GTRVIVNSRAIARDPSSW 552 G++V+++ + R+P W Sbjct: 424 GSQVLLSRYGLGRNPKVW 441
>C79B2_ARATH (O81346) Cytochrome P450 79B2 (EC 1.14.-.-)| Length = 541 Score = 84.0 bits (206), Expect = 3e-16 Identities = 42/138 (30%), Positives = 79/138 (57%), Gaps = 3/138 (2%) Frame = +1 Query: 148 DYIHDLLSIQKEYN---LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQ 318 D++ +SI+ E LT +++K + + A D +E+AMA ++ P+++ K Sbjct: 304 DFLDIFISIKDEQGNPLLTADEIKPTIKELVMAAPDNPSNAVEWAMAEMVNKPEILRKAM 363 Query: 319 AEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPS 498 E+ + K + +V E D+ L Y+KA+++E RLH A +PH+A++D + GY IP Sbjct: 364 EEIDRVVGK-ERLVQESDIPKLNYVKAILREAFRLHPVAAFNLPHVALSDTTVAGYHIPK 422 Query: 499 GTRVIVNSRAIARDPSSW 552 G++V+++ + R+P W Sbjct: 423 GSQVLLSRYGLGRNPKVW 440
>TCMO_PETCR (Q43033) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 506 Score = 83.6 bits (205), Expect = 4e-16 Identities = 44/133 (33%), Positives = 79/133 (59%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I ++ Q++ + + V + + A +T+ +E+ +A L+ NP++ KL+ E+ + Sbjct: 280 IDHIIEAQQKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNNPEIQKKLRHELDT 339 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G + E D+ L YL+AVIKETLR M PLLVPH+ + D + GY IP+ ++++ Sbjct: 340 VLGAGVQ-ICEPDVQKLPYLQAVIKETLRYRMAIPLLVPHMNLHDAKLAGYDIPAESKIL 398 Query: 514 VNSRAIARDPSSW 552 VN+ +A +P+ W Sbjct: 399 VNAWWLANNPAHW 411
>C71AS_ARATH (P58047) Cytochrome P450 71A28 (EC 1.14.-.-)| Length = 488 Score = 82.8 bits (203), Expect = 6e-16 Identities = 53/170 (31%), Positives = 93/170 (54%), Gaps = 4/170 (2%) Frame = +1 Query: 7 PELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQ--- 177 P L +D +R + + V+K + + LE ++ EH + + D++ D+L IQ Sbjct: 225 PGLAWIDKVRGLD-RKMEEVSKTFVEFLERVVQEHVDEGENK--ETFDFV-DILLIQLEK 280 Query: 178 -KEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 E+ L R ++ ++ F GT T++ +++AM ++++P+ M KLQ E+++ + K Sbjct: 281 TNEFELERSDIRLIILEFFLGGTTTTFTAIDWAMTLVVRHPESMKKLQEEIQT-YSRNKL 339 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGT 504 V E+++ ++ YLKAVIKE RLH P PL +P D IN + I T Sbjct: 340 YVPEEEVENMKYLKAVIKEVFRLHPPGPLSIPRQLSEDVFINAWAIHRDT 389
>TCMO_CATRO (P48522) Trans-cinnamate 4-monooxygenase (EC 1.14.13.11) (Cinnamic| acid 4-hydroxylase) (CA4H) (C4H) (P450C4H) (Cytochrome P450 73) Length = 505 Score = 82.0 bits (201), Expect = 1e-15 Identities = 43/134 (32%), Positives = 78/134 (58%) Frame = +1 Query: 154 IHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRS 333 I +L Q++ + + V + + A +T+ +E+ +A L+ +P++ KL+ E+ + Sbjct: 279 IDHILEAQQKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRDELET 338 Query: 334 SIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + G + E D L YL+AVIKETLRL M PL +PH+ + D + GY IP+ ++++ Sbjct: 339 VLGPGVQ-ITEPDTYKLPYLQAVIKETLRLRMAIPLFLPHMNLHDAKLGGYDIPAESKIL 397 Query: 514 VNSRAIARDPSSWE 555 VN+ +A +P W+ Sbjct: 398 VNAWFLANNPEHWK 411
>CP17A_RAT (P11715) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 80.1 bits (196), Expect = 4e-15 Identities = 39/110 (35%), Positives = 66/110 (60%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+++ +A L+ NP++ K+Q E+ + + +D +HL L+A I Sbjct: 298 IFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTF-NDRSHLLMLEATI 356 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 +E LR+ AP+L+PH A D I +T+P T V+VN A+ D + W+ Sbjct: 357 REVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWD 406
>C77A3_SOYBN (O48928) Cytochrome P450 77A3 (EC 1.14.-.-)| Length = 513 Score = 79.7 bits (195), Expect = 5e-15 Identities = 40/105 (38%), Positives = 61/105 (58%) Frame = +1 Query: 238 GTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETL 417 GTDT+ +E+ +A+L+ NP++ TKL E++ ++ G+ V E D+ + YL AV+KE L Sbjct: 311 GTDTTATAVEWGIAQLIANPNVQTKLYEEIKRTV--GEKKVDEKDVEKMPYLHAVVKELL 368 Query: 418 RLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 R H P ++ H + GY IP V V + AIA DP +W Sbjct: 369 RKHPPTHFVLTHAVTEPTTLGGYDIPIDANVEVYTPAIAEDPKNW 413
>CP17A_ONCMY (P30437) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 514 Score = 79.7 bits (195), Expect = 5e-15 Identities = 39/111 (35%), Positives = 66/111 (59%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+++A+A L+ +P + ++Q E+ S+ G D L YL+A I Sbjct: 306 IFGAGVETTSTVLKWAIAYLIHHPQVQQRIQEEL-DSVVGGDRTPQLSDRGSLPYLEATI 364 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 +E LR+ APLL+PH+A D I +T+ G R+I+N ++ D W++ Sbjct: 365 REVLRIRPVAPLLIPHVAQTDTSIGKFTVRKGARIIINLWSLHHDEKEWKN 415
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 79.3 bits (194), Expect = 7e-15 Identities = 57/197 (28%), Positives = 97/197 (49%), Gaps = 19/197 (9%) Frame = +1 Query: 22 LDIIRWMVCGRARRVN------KMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK- 180 +DI W+ + V+ K+ D++L ++ + + K D + DLL K Sbjct: 215 VDIFPWLTIFPNKTVDMIKKNVKIRDEVLSGILEKCKEK---FNSDSISSLMDLLIQAKT 271 Query: 181 --EYNLTRE----------QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAE 324 + N T E + A + +FGAG +T+ V+ + +A L+ NP++ K+Q E Sbjct: 272 NADNNNTSEGQGSNAFSDMHILATIADIFGAGIETTASVLSWIIAFLLHNPEVKKKIQKE 331 Query: 325 VRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGT 504 + +I + +D NHL L+A I+E LR+ AP+L+PH A +D I ++IP T Sbjct: 332 IDQNIGFSRTPTF-NDRNHLLMLEATIREVLRIRPVAPMLIPHRANSDMSIGEFSIPKFT 390 Query: 505 RVIVNSRAIARDPSSWE 555 VI+N A+ W+ Sbjct: 391 PVIINLWALHHSEKEWD 407
>CP17A_PERLE (Q91Z85) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 78.2 bits (191), Expect = 1e-14 Identities = 40/109 (36%), Positives = 64/109 (58%) Frame = +1 Query: 229 FGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIK 408 FGAG +T+ V+ + +A L+ NP++ K+Q E+ +I + +D NHL L+A I+ Sbjct: 298 FGAGIETTTSVLCWIVAFLLHNPEVKKKIQKEIDQNIGFSRTPTF-NDRNHLLMLEATIR 356 Query: 409 ETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E LR+ AP+L+PH A D I +TIP T V++N A+ + W+ Sbjct: 357 EVLRIRPVAPMLIPHKANIDSSIGEFTIPKDTHVVINLWALHHNEKEWD 405
>CP17A_ORYLA (P70085) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 517 Score = 77.8 bits (190), Expect = 2e-14 Identities = 49/172 (28%), Positives = 89/172 (51%), Gaps = 14/172 (8%) Frame = +1 Query: 79 DDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK--EYNLTREQVKAQLVIM-------- 228 D LL+ EH+S + + D + LL ++ E N T + A+ V + Sbjct: 247 DQLLQKKFEEHKSDYSDHV--QRDLLDALLRAKRSAENNNTAAEFSAEAVGLSDDHLLMT 304 Query: 229 ----FGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 FGAG +T+ V+++A+ L+ P++ ++Q E+ + + + D L +L+ Sbjct: 305 VGDIFGAGVETTTTVLKWAITYLIHYPEVQKQIQEELDRKVGVDRPPQLSDR-GSLPFLE 363 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 A I+E LR+ APLL+PH+A++D + +T+ GTRV++N ++ D W Sbjct: 364 ATIREVLRIRPVAPLLIPHVALSDTSLGDFTVRKGTRVVINLWSLHHDEKEW 415
>C77A2_SOLME (P37124) Cytochrome P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2)| (P-450EG5) Length = 511 Score = 77.8 bits (190), Expect = 2e-14 Identities = 36/105 (34%), Positives = 63/105 (60%) Frame = +1 Query: 238 GTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETL 417 GTDT+ +E+A+ RL++NP++ ++L E++ ++ G++ + E D+ + YL AV+KE L Sbjct: 316 GTDTTATAIEWAIGRLIENPNIQSQLYEEIKKTV--GENKIDEKDIEKMPYLNAVVKELL 373 Query: 418 RLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 R H P + + H + GY IP+G V + I+ DP+ W Sbjct: 374 RKHPPTYMSLTHAVTEPAKLGGYDIPTGVNVEIFLPGISDDPNLW 418
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 77.0 bits (188), Expect = 3e-14 Identities = 40/110 (36%), Positives = 63/110 (57%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+ + +A L+ NP++ K+Q E+ + + +D HL L+A I Sbjct: 298 IFGAGIETTSSVLNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSF-NDRTHLLMLEATI 356 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 +E LR+ APLL+PH A D I + IP T VI+N A+ D + W+ Sbjct: 357 REVLRIRPVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEWD 406
>CP17A_HORSE (Q95328) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 76.3 bits (186), Expect = 6e-14 Identities = 39/121 (32%), Positives = 69/121 (57%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ + + A + +FGAG +T+ V+++ +A L+ +P L K+Q E+ ++ + + D Sbjct: 287 LSDKHILATIGDIFGAGVETTTSVVKWIVAFLLHDPQLKKKIQEEIDQNVGFSRTPTLSD 346 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 N L L+A I+E LR+ AP+L+PH A+ D I + + GT VI+N A+ + Sbjct: 347 R-NRLLLLEATIREVLRIRPVAPMLIPHKALVDSSIGEFAVDDGTNVIINLWALHHNEKE 405 Query: 550 W 552 W Sbjct: 406 W 406
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 75.9 bits (185), Expect = 7e-14 Identities = 46/167 (27%), Positives = 81/167 (48%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMF 231 R+ + M D L+++ ++ P D++ + D + + +F Sbjct: 255 RSDSITNMLDTLMQAKMNSDNGNAGP--DQDSELLSD------------NHILTTIGDIF 300 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 GAG +T+ V+++ +A L+ NP + KL E+ ++ + I D N L L+A I+E Sbjct: 301 GAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDR-NRLLLLEATIRE 359 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 LRL AP+L+PH A D I + + GT+VI+N A+ + W Sbjct: 360 VLRLRPVAPMLIPHKANVDSSIGEFAVDKGTQVIINLWALHHNEKEW 406
>CP17A_CAVPO (Q64410) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 75.9 bits (185), Expect = 7e-14 Identities = 48/168 (28%), Positives = 85/168 (50%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMF 231 R+ V+ + D L+++ ++E+ + + L D++ D + + L +F Sbjct: 255 RSDSVSNLIDLLIQAKVNENNNNSS--LDQDSNLFSD------------KHILTTLGDIF 300 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 GAG +TS V+ + +A L+ NP + K+Q E+ ++ + D NHL L+A I+E Sbjct: 301 GAGVETSSSVVLWVIAFLLHNPQVKKKIQEEIDHNVGFSRTPTFSDR-NHLLMLEATIRE 359 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LR+ AP+L+PH A D I + I T V+VN A+ + W+ Sbjct: 360 VLRIRPVAPILIPHKANTDSSIGEFAIDKDTNVLVNLWALHHNEQEWD 407
>CP17A_SHEEP (Q29497) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 75.9 bits (185), Expect = 7e-14 Identities = 41/122 (33%), Positives = 68/122 (55%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ + A + +FGAG +T+ V+++ +A L+ +P L ++Q + +I + I D Sbjct: 287 LSNRHMLATIADIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISD 346 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 N L L+A I+E LR+ AP+L+PH A+ D I TI GT V+VN A+ + Sbjct: 347 R-NRLVLLEATIREVLRIRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKE 405 Query: 550 WE 555 W+ Sbjct: 406 WQ 407
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 75.5 bits (184), Expect = 1e-13 Identities = 46/167 (27%), Positives = 80/167 (47%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMF 231 R+ + M D L+++ ++ P D++ + D + + +F Sbjct: 255 RSDSITNMLDTLMQAKMNSDNGNAGP--DQDSELLSD------------NHILTTIGDIF 300 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKE 411 GAG +T+ V+++ +A L+ NP + KL E+ ++ + I D N L L+A I+E Sbjct: 301 GAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDR-NRLLLLEATIRE 359 Query: 412 TLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 LRL AP+L+PH A D I + + GT VI+N A+ + W Sbjct: 360 VLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
>C77A1_SOLME (P37123) Cytochrome P450 77A1 (EC 1.14.-.-) (CYPLXXVIIA1)| (P-450EG6) (Fragment) Length = 499 Score = 75.5 bits (184), Expect = 1e-13 Identities = 55/189 (29%), Positives = 90/189 (47%), Gaps = 12/189 (6%) Frame = +1 Query: 22 LDIIRWMVCGRAR-RVNKMWDDLLESLIHEHESKPAPALGDDTD-------YIHDLLSIQ 177 L I+R V + R RVN++ +E+L+ E + + +D Y+ L ++ Sbjct: 220 LPILRLFVGYKQRKRVNEVRKRQIETLVPLIEKRRSVVQNPGSDKTAASFSYLDTLFDVK 279 Query: 178 KEYNLTREQVKAQLVIM----FGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPK 345 E + A+LV + GTDT+ +E+ + RLM+NP + +L E+++ + Sbjct: 280 VEGRKSGP-TNAELVTLCSEFLNGGTDTTATALEWGIGRLMENPTIQNQLYQEIKTIV-- 336 Query: 346 GKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSR 525 G V E+D+ + YL AV+KE LR H P + H + GY IP T V Sbjct: 337 GDKKVDENDIEKMPYLNAVVKELLRKHPPTYFTLTHSVTEPVKLAGYDIPMDTNVEFFVH 396 Query: 526 AIARDPSSW 552 I+ DP+ W Sbjct: 397 GISHDPNVW 405
>CP2D3_RAT (P12938) Cytochrome P450 2D3 (EC 1.14.14.1) (CYPIID3) (P450-DB3)| (Debrisoquine 4-hydroxylase) Length = 500 Score = 75.1 bits (183), Expect = 1e-13 Identities = 51/192 (26%), Positives = 97/192 (50%), Gaps = 8/192 (4%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRV---NKMWDDLLESLIHEHESK--PAPALGDDTD-YIHDL 165 FPE+L + + + G A +V K + ++++L+ EH+ P D TD ++ ++ Sbjct: 223 FPEVLNMFPVLLRIPGLADKVFPGQKTFLTMVDNLVTEHKKTWDPDQPPRDLTDAFLAEI 282 Query: 166 LSIQKEYNLTREQVKAQLVI--MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSI 339 + + +LV+ +FGAG T+ I + +A+ ++ +PD+ ++Q E+ I Sbjct: 283 EKAKGNPESSFNDANLRLVVNDLFGAGMVTTSITLTWALLLMILHPDVQCRVQQEIDEVI 342 Query: 340 PKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVN 519 + +H + D H+ + AVI E R P+ +PH D + G+ IP GT +I N Sbjct: 343 GQVRHPEMADQA-HMPFTNAVIHEVQRFADIVPMNLPHKTSRDIEVQGFLIPKGTTLIPN 401 Query: 520 SRAIARDPSSWE 555 ++ +D + WE Sbjct: 402 LSSVLKDETVWE 413
>CP17A_CAPHI (Q9N0U7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 74.7 bits (182), Expect = 2e-13 Identities = 41/122 (33%), Positives = 68/122 (55%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ + A + +FGAG +T+ V+++ +A L+ +P L ++Q + +I + I D Sbjct: 287 LSNRHMLATIADIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISD 346 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 N L L+A I+E LR+ AP+L+PH A+ D I TI GT V+VN A+ + Sbjct: 347 R-NCLVLLEATIREVLRIRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKE 405 Query: 550 WE 555 W+ Sbjct: 406 WQ 407
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 73.6 bits (179), Expect = 4e-13 Identities = 39/109 (35%), Positives = 61/109 (55%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+ + +A L+ +P L KLQ E+ +I + + D N L L+A I Sbjct: 299 IFGAGVETTTSVVRWTVAFLLHHPQLYKKLQEEIDQNIGFSRTPTMSDR-NQLILLEATI 357 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 +E LR+ AP L+PH A+ D I + + GT VI+N A+ + W Sbjct: 358 REVLRIRPVAPTLIPHKAIMDSSIGEFAVDKGTNVIINLWALHHNEKEW 406
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 73.2 bits (178), Expect = 5e-13 Identities = 38/109 (34%), Positives = 61/109 (55%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+++ +A L+ NP + KL E+ ++ + I D N L L+A I Sbjct: 299 IFGAGVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDR-NRLLLLEATI 357 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 +E LR+ AP+L+PH A D I + + GT VI+N A+ + W Sbjct: 358 REVLRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW 406
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 73.2 bits (178), Expect = 5e-13 Identities = 38/109 (34%), Positives = 61/109 (55%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+++ +A L+ NP + KL E+ ++ + I D N L L+A I Sbjct: 299 IFGAGVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDR-NRLLLLEATI 357 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 +E LR+ AP+L+PH A D I + + GT VI+N A+ + W Sbjct: 358 REVLRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW 406
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 73.2 bits (178), Expect = 5e-13 Identities = 38/109 (34%), Positives = 61/109 (55%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+++ +A L+ NP + KL E+ ++ + I D N L L+A I Sbjct: 299 IFGAGVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDR-NRLLLLEATI 357 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 +E LR+ AP+L+PH A D I + + GT VI+N A+ + W Sbjct: 358 REVLRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW 406
>CP17A_BOVIN (P05185) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 72.8 bits (177), Expect = 6e-13 Identities = 41/122 (33%), Positives = 66/122 (54%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ + A + +FGAG +T+ V+++ +A L+ +P L ++Q ++ I + I D Sbjct: 287 LSNRHMLATIGDIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPTISD 346 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 N L L+A I+E LR+ AP L+PH A+ D I TI GT V+VN A+ Sbjct: 347 R-NRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKE 405 Query: 550 WE 555 W+ Sbjct: 406 WQ 407
>CP1A1_PLAFE (Q9YH64) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 72.4 bits (176), Expect = 8e-13 Identities = 45/171 (26%), Positives = 82/171 (47%), Gaps = 6/171 (3%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI---- 225 R+N + + ++ ++ EH + + D TD + D +K + Q+ + ++ Sbjct: 258 RINSRFTEFVQKIVTEHYTTFDKDNIRDITDSLIDHCEDRKLDENSNVQMSDEKIVGIVN 317 Query: 226 -MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 +FGAG DT + +++ L+ +P++ +L E+ + + ++ D N L +L+A Sbjct: 318 DLFGAGFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPN-LPFLEAF 376 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 I E LR P +PH D +NGY IP T V +N I DP W+ Sbjct: 377 ILEILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPELWK 427
>CP1A1_ONCMY (Q92110) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (CYP1A2)| Length = 522 Score = 72.4 bits (176), Expect = 8e-13 Identities = 46/170 (27%), Positives = 81/170 (47%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N +++ ++ ++ EH ES + D TD + D +K QV + ++ Sbjct: 259 INDRFNNFVQKIVSEHYESYDKDNIRDITDSLIDHCEDRKLDENANIQVSDEKIVGIVND 318 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +A+ L+ P++ +L E++ + + + D +N L L+A I Sbjct: 319 LFGAGFDTISTALSWAVVYLVAYPEIQERLHQELKEKVGMIRTPRLSDKIN-LPLLEAFI 377 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH + D +NGY IP T V +N + DP W+ Sbjct: 378 LEIFRHSSFLPFTIPHCTIKDTSLNGYFIPKDTCVFINQWQVNHDPELWK 427
>CP17A_BISBI (Q9GMC7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 72.4 bits (176), Expect = 8e-13 Identities = 41/122 (33%), Positives = 66/122 (54%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ + A + +FGAG +T+ V+++ +A L+ +P L ++Q ++ I + I D Sbjct: 287 LSSRHMLATIGDIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPAISD 346 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 N L L+A I+E LR+ AP L+PH A+ D I TI GT V+VN A+ Sbjct: 347 R-NRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKE 405 Query: 550 WE 555 W+ Sbjct: 406 WQ 407
>CP1A1_PLEPL (Q92100) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/171 (26%), Positives = 83/171 (48%), Gaps = 6/171 (3%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI---- 225 R+N+ + + ++ ++ EH + + D TD + D +K + Q+ + ++ Sbjct: 258 RINEHFTEFVQKIVTEHYTTFNKDNIRDITDSLIDHCEDRKLDENSNVQMSDEKIVGIVN 317 Query: 226 -MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 +FGAG DT + +++ L+ +P++ +L E+ + + ++ D N L +L+A Sbjct: 318 DLFGAGFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPN-LPFLEAF 376 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 I E LR P +PH D +NGY IP T V +N I DP W+ Sbjct: 377 ILEILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPELWK 427
>CP1A1_LIMLI (O42430) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/171 (26%), Positives = 82/171 (47%), Gaps = 6/171 (3%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI---- 225 R+N + + ++ ++ EH + + D TD + D +K + Q+ + ++ Sbjct: 258 RINGRFTEFVQKIVTEHYTTFDKDNIRDITDSLIDHCEDRKLDENSNVQMSDEKIVGIVN 317 Query: 226 -MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 +FGAG DT + +++ L+ +P++ +L E+ + + ++ D N L +L+A Sbjct: 318 DLFGAGFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPN-LPFLEAF 376 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 I E LR P +PH D +NGY IP T V +N I DP W+ Sbjct: 377 ILEILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPEMWK 427
>CP2K4_ONCMY (O93297) Cytochrome P450 2K4 (EC 1.14.14.1) (CYPIIK4)| Length = 504 Score = 71.6 bits (174), Expect = 1e-12 Identities = 38/111 (34%), Positives = 58/111 (52%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAGTDT+ + + + + + P + ++Q E+ I G + +D +L Y AVI Sbjct: 307 LFGAGTDTTGTTLRWGLLLMAKYPHIQDQVQEEISRVI--GSRQTLVEDRKNLPYTDAVI 364 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 ET RL +P+ VPH D GY I GT VI ++ +D + WES Sbjct: 365 HETQRLANISPMAVPHTTSRDVTFQGYFIKKGTSVIPLLMSVLQDDNEWES 415
>CP1A3_ONCMY (Q92109) Cytochrome P450 1A3 (EC 1.14.14.1) (CYP1A3) (CYP1A1)| Length = 522 Score = 71.2 bits (173), Expect = 2e-12 Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N +++ ++ ++ EH ES + D TD + D +K QV + ++ Sbjct: 259 INDRFNNFVQKIVSEHYESYDKDNIRDITDSLIDHCEDRKLDENANIQVSDEKIVGIVND 318 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +A+ L+ P+ +L E++ + + + D +N L L+A I Sbjct: 319 LFGAGFDTISTALSWAVVYLVAYPETQERLHQELKEKVGMIRTPRLSDKIN-LPLLEAFI 377 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH + D +NGY IP T V +N + DP W+ Sbjct: 378 LEIFRHSSFLPFTIPHCTIKDTSLNGYFIPKDTCVFINQWQVNHDPELWK 427
>CP27A_RAT (P17178) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 71.2 bits (173), Expect = 2e-12 Identities = 55/175 (31%), Positives = 87/175 (49%), Gaps = 12/175 (6%) Frame = +1 Query: 58 RRVNKMWDDLL---ESLIHEHESK---PAPALGDD----TDYIHDLLSIQKEYNLTREQV 207 +R WD++ E +IH+ + A G D + Y+H LL+ KE +E V Sbjct: 271 KRYMNNWDNIFSFGEKMIHQKVQEIEAQLQAAGPDGVQVSGYLHFLLT--KELLSPQETV 328 Query: 208 KA--QLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 +L++ AG DT+ + +A+ L +NP++ L EV +P GK + D H Sbjct: 329 GTFPELIL---AGVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVVPFGK-VPQNKDFAH 384 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPS 546 + LKAVIKETLRL+ P + + ING+ P T+ ++ ++RDPS Sbjct: 385 MPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPS 439
>CP2J6_MOUSE (O54750) Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic| acid epoxygenase) Length = 501 Score = 70.9 bits (172), Expect = 2e-12 Identities = 51/187 (27%), Positives = 86/187 (45%), Gaps = 11/187 (5%) Frame = +1 Query: 25 DIIRWM---VCGRARRVNKMWDDL---LESLIHEHESKPAPALGDDTDYIHDLLSIQKEY 186 +I W+ + G ++V + W+ L + +I +H P + D+I L +Y Sbjct: 231 NIFPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDWNP--DEPRDFIDAFLKEMTKY 288 Query: 187 -----NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGK 351 + E + + +F AGT+T+ + +A+ + P++ K+QAE+ I + K Sbjct: 289 PEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQ-K 347 Query: 352 HMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAI 531 D + Y AVI E R+ PL VP D +NG+ +P GT V+ N A+ Sbjct: 348 RAARLADRESMPYTNAVIHEVRRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTAL 407 Query: 532 ARDPSSW 552 RDP W Sbjct: 408 HRDPKEW 414
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 70.5 bits (171), Expect = 3e-12 Identities = 37/109 (33%), Positives = 60/109 (55%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG +T+ V+++ +A L+ NP + KL + ++ + I D N L L+A I Sbjct: 299 IFGAGVETTTSVVKWIVAFLLHNPQVKKKLYEGIDQNVGFSRTPTISDR-NRLLLLEATI 357 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 +E LR+ AP+L+PH A D I + + GT VI+N A+ + W Sbjct: 358 REVLRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW 406
>KO1_ARATH (Q93ZB2) Ent-kaurene oxidase (EC 1.14.13.78) (AtKO1) (Cytochrome| P450 701A3) Length = 509 Score = 70.5 bits (171), Expect = 3e-12 Identities = 43/139 (30%), Positives = 70/139 (50%) Frame = +1 Query: 139 DDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQ 318 DD Y++ L+S K LT+EQ+ + DT+ + E+A+ L ++P + +L Sbjct: 286 DDDCYLNFLMSEAK--TLTKEQIAILVWETIIETADTTLVTTEWAIYELAKHPSVQDRLC 343 Query: 319 AEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPS 498 E+++ G E+ L+ + YL V ETLR + PAPL+ A D I GY +P+ Sbjct: 344 KEIQNVC--GGEKFKEEQLSQVPYLNGVFHETLRKYSPAPLVPIRYAHEDTQIGGYHVPA 401 Query: 499 GTRVIVNSRAIARDPSSWE 555 G+ + +N D WE Sbjct: 402 GSEIAINIYGCNMDKKRWE 420
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 70.1 bits (170), Expect = 4e-12 Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 2/143 (1%) Frame = +1 Query: 121 PAPALGDDTDYIHDLLSIQKEYN--LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQN 294 P P+ ++ LLS+ E L++E ++ ++ G DT+ + +++ L N Sbjct: 289 PIPSKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTN 348 Query: 295 PDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCV 474 P++ K+ E+ + V +DL L YL VIKETLR+ PL L+ DC Sbjct: 349 PEVQRKVDQELDEVFGRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLS-EDCE 407 Query: 475 INGYTIPSGTRVIVNSRAIARDP 543 + GY + GT I+ A+ RDP Sbjct: 408 VGGYKVTKGTEAIIIPYALHRDP 430
>CP1A2_PONPY (Q5RBQ1) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 70.1 bits (170), Expect = 4e-12 Identities = 38/110 (34%), Positives = 56/110 (50%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ P++ K+Q E+ + I +G+ + D L YLKA I Sbjct: 313 IFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTMIGRGRRPRLSDR-PQLPYLKAFI 371 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 ET R P +PH D +NG+ IP V VN + DP WE Sbjct: 372 LETFRHSSFLPFTIPHSTTRDTTLNGFYIPKECCVFVNQWQVNHDPELWE 421
>CP21A_CANFA (Q8WNW0) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 70.1 bits (170), Expect = 4e-12 Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 12/180 (6%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQL--- 219 R +R + D ++E + +H ES A D TDY+ +Q+ L E+ QL Sbjct: 223 RLKRALENRDHIVEKQLRQHKESMVAGQWRDMTDYM-----LQRVGRLRAEEGCGQLLEG 277 Query: 220 ------VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH--MVIEDDL 375 V +F GT+T+ + +A+A L+ +P++ +LQ E+ + G + D Sbjct: 278 HVHMSVVDLFIGGTETTATTLSWAVAFLLHHPEIQQRLQEELDRELGPGASGSRIPYRDP 337 Query: 376 NHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 L L A + E LRL PL +PH I+GY IP G VI N + D + WE Sbjct: 338 TRLPLLSATVAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGMVVIPNLQGAHLDETVWE 397
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 69.7 bits (169), Expect = 5e-12 Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 8/145 (5%) Frame = +1 Query: 142 DTDYIHDLLS--------IQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNP 297 DTD++ D ++ + +LT +++ QL + AG DT+ + + Y+ L ++P Sbjct: 287 DTDFLEDETKNGFARSQIVKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHP 346 Query: 298 DLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVI 477 ++ KLQ EV P + V D L+ L Y++ VIKETLRL+ A ++ M + Sbjct: 347 EIQKKLQEEVDRECPDPE--VTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTV 404 Query: 478 NGYTIPSGTRVIVNSRAIARDPSSW 552 G I GT V ++ + DP W Sbjct: 405 LGMKIEEGTNVQADTWTLHYDPKFW 429
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 69.7 bits (169), Expect = 5e-12 Identities = 42/117 (35%), Positives = 64/117 (54%) Frame = +1 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 +V AQ +I+ AG +T+ + + M L +PD+ KLQ E+ + +P K + D L Sbjct: 292 EVVAQSIIILFAGYETTSSTLSFIMHLLATHPDVQQKLQEEIDTLLP-NKELATYDTLVK 350 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + YL V+ ETLRL+ P + + D ING IP GT V++ + A+ RDP W Sbjct: 351 MEYLDMVVNETLRLY-PIAGRLERVCKKDVDINGTFIPKGTIVMMPTYALHRDPQHW 406
>CP1B1_MOUSE (Q64429) Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) (P450CMEF)| (P450EF) Length = 543 Score = 69.7 bits (169), Expect = 5e-12 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = +1 Query: 82 DLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIV 261 D+ ++ I E K + GDD+ L E V A + +FGA DT Sbjct: 291 DMTDAFILSAEKKASGDPGDDSS------------GLDLEDVPATITDIFGASQDTLSTA 338 Query: 262 MEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPL 441 + + + + PD+ ++QAE+ + + + + D N L Y+ A + E++R P+ Sbjct: 339 LLWLLILFTRYPDVQARVQAELDQVVGRDRLPCMSDQPN-LPYVMAFLYESMRFSSFLPV 397 Query: 442 LVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 +PH A+ + GY IP T V VN ++ DP+ W Sbjct: 398 TIPHATTANTFVLGYYIPKNTVVFVNQWSVNHDPAKW 434
>CP2K1_ONCMY (Q92090) Cytochrome P450 2K1 (EC 1.14.14.1) (CYPIIK1) (P450 LMC2)| Length = 504 Score = 69.7 bits (169), Expect = 5e-12 Identities = 38/111 (34%), Positives = 56/111 (50%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +F AGTDT+ + + + + + P + ++Q E+ I G + +D +L Y AVI Sbjct: 307 LFSAGTDTTGTTLRWGLLLMTKYPHIQDQVQEEISRVI--GSRQTLVEDRKNLPYTDAVI 364 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 ET RL P+ VPH D GY I GT VI ++ +D S WES Sbjct: 365 HETQRLANIVPMSVPHTTSRDVTFQGYFIKKGTSVIPLLTSVLQDDSEWES 415
>CP2C9_HUMAN (P11712) Cytochrome P450 2C9 (EC 1.14.13.80) ((R)-limonene| 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 6-monooxygenase) (EC 1.14.13.49) ((S)-limonene 7-monooxygenase) (CYPIIC9) (P450 PB-1) (P450 MP-4/MP-8) (S-mephenytoin 4-hydroxylase) (P- Length = 490 Score = 69.3 bits (168), Expect = 7e-12 Identities = 37/131 (28%), Positives = 69/131 (52%), Gaps = 5/131 (3%) Frame = +1 Query: 163 LLSIQKEYN-----LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEV 327 L+ ++KE + T E ++ V +FGAGT+T+ + YA+ L+++P++ K+Q E+ Sbjct: 268 LMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEI 327 Query: 328 RSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTR 507 I + + ++ D +H+ Y AV+ E R P +PH D Y IP GT Sbjct: 328 ERVIGRNRSPCMQ-DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTT 386 Query: 508 VIVNSRAIARD 540 ++++ ++ D Sbjct: 387 ILISLTSVLHD 397
>C97B1_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2)| Length = 552 Score = 69.3 bits (168), Expect = 7e-12 Identities = 44/125 (35%), Positives = 67/125 (53%), Gaps = 7/125 (5%) Frame = +1 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 Q++ L+ M AG +T+ V+ +A+ L QNPD M K QAEV + GK + L Sbjct: 351 QLRDDLMTMLIAGHETTAAVLTWAVFLLAQNPDKMKKAQAEVDLVLGMGKPTF--ELLKK 408 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCV-------INGYTIPSGTRVIVNSRAIARD 540 L Y++ ++ ETLRL+ PLL+ D + +GYTIP+GT V ++ + R Sbjct: 409 LEYIRLIVVETLRLYPQPPLLIRRSLKPDVLPGGHKGDKDGYTIPAGTDVFISVYNLHRS 468 Query: 541 PSSWE 555 P W+ Sbjct: 469 PYFWD 473
>CP1A1_MACMU (Q6GUR1) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 512 Score = 69.3 bits (168), Expect = 7e-12 Identities = 46/169 (27%), Positives = 81/169 (47%), Gaps = 6/169 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHD-----LLSIQKEYNLTREQVKAQLVI 225 +N+ + ++ +I EH ++ + D TD + + L L+ E++ ++ Sbjct: 254 LNEKFHSFMQKMIKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANIQLSDEKIVNVVLD 313 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ NP + K+Q E+ + I + + + D +HL Y++A I Sbjct: 314 LFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRSRRPRLSDR-SHLPYMEAFI 372 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ET R P +PH D + G+ IP G V VN I D W Sbjct: 373 LETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLW 421
>CP1A1_MACFA (P33616) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 512 Score = 69.3 bits (168), Expect = 7e-12 Identities = 46/169 (27%), Positives = 81/169 (47%), Gaps = 6/169 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHD-----LLSIQKEYNLTREQVKAQLVI 225 +N+ + ++ +I EH ++ + D TD + + L L+ E++ ++ Sbjct: 254 LNEKFHSFMQKMIKEHYKTFEKGYIRDITDSLIEHCQEKQLDENANIQLSDEKIVNVVLD 313 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ NP + K+Q E+ + I + + + D +HL Y++A I Sbjct: 314 LFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRSRRPRLSDR-SHLPYMEAFI 372 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ET R P +PH D + G+ IP G V VN I D W Sbjct: 373 LETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLW 421
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 68.9 bits (167), Expect = 9e-12 Identities = 41/121 (33%), Positives = 65/121 (53%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ ++ AQ VI AG +T+ + + + L +PD+ KLQ E+ +++P H D Sbjct: 290 LSDVEIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATY-D 348 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 L + YL V+ ETLRL+ P + + D ING IP GT V++ + A+ +DP Sbjct: 349 TLLQMEYLDMVVNETLRLY-PIAGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHY 407 Query: 550 W 552 W Sbjct: 408 W 408
>CP1A1_ORYLA (Q6JZS3) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 68.9 bits (167), Expect = 9e-12 Identities = 47/170 (27%), Positives = 77/170 (45%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N + ++ +++EH + + D TD + D +K + Q+ + V+ Sbjct: 259 INNRFQSFVQKIVNEHSATYDKDNIRDITDSLIDHCEDRKLDENSNIQMSDEKVVGIVND 318 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +A+ L+ PD+ L E++ +I ++ I D N L A I Sbjct: 319 LFGAGFDTISTALSWAVGYLVAYPDIEKGLFEEIKENIGLNRNPTISDRSN-LPLTDAFI 377 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH D +NGY IP T V +N I DP W+ Sbjct: 378 LEIFRHSSFLPFTIPHCTTRDTSLNGYYIPKDTCVFINQWQINHDPKLWQ 427
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/121 (34%), Positives = 66/121 (54%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ ++ AQ VI AG +T+ + +A+ L +PD+ KLQ E+ +++P K D Sbjct: 290 LSDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALP-NKAPATYD 348 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 L + YL V+ ETLRL+ P + + D ING IP GT V++ + A+ +DP Sbjct: 349 TLLQMEYLDMVVNETLRLY-PIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKY 407 Query: 550 W 552 W Sbjct: 408 W 408
>CP21A_PIG (P15540) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 68.6 bits (166), Expect = 1e-11 Identities = 53/166 (31%), Positives = 75/166 (45%), Gaps = 7/166 (4%) Frame = +1 Query: 79 DDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQK----EYNLTREQVKAQLVIMFGAGT 243 D L+E + H ES A D DY+ Q+ + L V +V +F GT Sbjct: 233 DHLVEKQLRRHKESMVAGQWRDMLDYMLQEAGRQRVEEGQGQLLEGHVHMSVVDLFIGGT 292 Query: 244 DTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGK--HMVIEDDLNHLAYLKAVIKETL 417 +T+ + +A+ L+ +P++ +LQ E+ + G V D L L A I E L Sbjct: 293 ETTANTLSWAVVYLLHHPEIQWRLQEELDRELGPGAAGSRVPYKDRARLPLLNATIAEVL 352 Query: 418 RLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 RL PL +PH A I GY IP GT VI N + D + WE Sbjct: 353 RLRPVVPLALPHRATRPSSIFGYDIPEGTVVIPNLQGAHLDETVWE 398
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 68.6 bits (166), Expect = 1e-11 Identities = 42/130 (32%), Positives = 66/130 (50%) Frame = +1 Query: 163 LLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIP 342 ++ I KE LT +++ AQ + AG DT+ + + YA L +P++ TKLQ EV P Sbjct: 302 VVKINKE--LTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVDRECP 359 Query: 343 KGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNS 522 + + D L+ L YL+ V+KETLRL+ M + ING G + V++ Sbjct: 360 DPE--IFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTINGVNFDEGMNIQVDT 417 Query: 523 RAIARDPSSW 552 + +P W Sbjct: 418 WTLHHNPRIW 427
>CP2C7_RAT (P05179) Cytochrome P450 2C7 (EC 1.14.14.1) (CYPIIC7) (P450F)| (PTF1) Length = 490 Score = 68.6 bits (166), Expect = 1e-11 Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 6/168 (3%) Frame = +1 Query: 55 ARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN------LTREQVKAQ 216 A+ +N M LL+ + ES D DY L QK+ N + E + Sbjct: 234 AKNINYMKSYLLKKIEEHQESLDVTNPRDFVDYY---LIKQKQANNIEQSEYSHENLTCS 290 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 ++ + GAGT+T + YA+ LM+ P + K+Q E+ I + + ++D H+ Y Sbjct: 291 IMDLIGAGTETMSTTLRYALLLLMKYPHVTAKVQEEIDRVIGRHRSPCMQDR-KHMPYTD 349 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 A+I E R P +PH D Y IP GT+V+ + ++ D Sbjct: 350 AMIHEVQRFINFVPTNLPHAVTCDIKFRNYLIPKGTKVLTSLTSVLHD 397
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/121 (33%), Positives = 64/121 (52%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ ++ AQ +I AG +T+ + + M L +PD+ KLQ E+ ++P K D Sbjct: 290 LSDVEILAQSIIFIFAGYETTSSTLSFIMYSLATHPDVQKKLQQEIDKTLP-NKAFPTYD 348 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 + + YL V+ ETLRL+ P + ++ D ING + P GT V++ S A+ RD Sbjct: 349 VMMEMEYLDMVVNETLRLY-PVTNRIERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKY 407 Query: 550 W 552 W Sbjct: 408 W 408
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/122 (37%), Positives = 64/122 (52%), Gaps = 3/122 (2%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 LT E+V AQ + F AG +TS M +A+ L +NPD+ K++AEV I + + Sbjct: 295 LTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYE 354 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVING---YTIPSGTRVIVNSRAIARD 540 L YL V+ ETLRL+ P L +A V+ G + I +G VI+ S AI D Sbjct: 355 CTKDLKYLNQVLDETLRLYTIVPNL-DRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHD 413 Query: 541 PS 546 PS Sbjct: 414 PS 415
>CP1A1_CHACA (Q92039) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 68.2 bits (165), Expect = 2e-11 Identities = 44/170 (25%), Positives = 83/170 (48%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQK-----EYNLTREQVKAQLVI 225 +N ++ ++ ++ EH + + D TD + D +K ++ E++ + Sbjct: 259 INADFNTFVKKIVGEHYATFDKNNIRDITDSLIDHCEDRKLDENCNVQMSDEKIVGIVND 318 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ PD+ +L E++ ++ + ++ D + + YL+A I Sbjct: 319 LFGAGFDTVSTALSWSVMYLVAYPDIQERLFQEIKDNVGLDRTPLLSDR-SKVPYLEAFI 377 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH + D +NGY IP T V +N I RDP W+ Sbjct: 378 LELFRHSSFLPFTIPHCSAKDTSLNGYFIPKDTCVFINQWQINRDPELWK 427
>CP1A1_HUMAN (P04798) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1)| (P450 form 6) (P450-C) Length = 512 Score = 67.8 bits (164), Expect = 2e-11 Identities = 45/169 (26%), Positives = 81/169 (47%), Gaps = 6/169 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHD-----LLSIQKEYNLTREQVKAQLVI 225 +N+ + ++ ++ EH ++ + D TD + + L L+ E++ ++ Sbjct: 254 LNEKFYSFMQKMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLD 313 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ NP + K+Q E+ + I + + + D +HL Y++A I Sbjct: 314 LFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDR-SHLPYMEAFI 372 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ET R P +PH D + G+ IP G V VN I D W Sbjct: 373 LETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLW 421
>CP1A1_MICTO (Q92148) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 515 Score = 67.8 bits (164), Expect = 2e-11 Identities = 45/174 (25%), Positives = 82/174 (47%), Gaps = 6/174 (3%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI- 225 R +N+ + ++ ++ EH + + D TD + D +K + Q+ + ++ Sbjct: 251 RFMAINERFMTFVQKIVTEHYNTYDKDNIRDITDSLIDHCEDRKLDENSNIQMSDEKIVG 310 Query: 226 ----MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYL 393 +FGAG DT + +++ L+ +P++ +L E++ + + V+ D N L L Sbjct: 311 IVNDLFGAGFDTVSTALSWSVMYLVAHPEIQERLHQEIKDKVGLSRSPVLTDRHN-LPIL 369 Query: 394 KAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 +A I E R P +PH A D ++GY IP T V +N I DP W+ Sbjct: 370 EAFIFEIFRHSSFLPFTIPHCATKDTSLDGYFIPKDTCVFINQWQINHDPELWK 423
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/117 (35%), Positives = 62/117 (52%) Frame = +1 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 ++ AQ +I AG +T+ V+ + M L +PD+ KLQ E+ + +P K D + Sbjct: 294 ELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQ 352 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + YL V+ ETLRL P + + + D ING IP G V++ S A+ RDP W Sbjct: 353 MEYLDMVVNETLRL-FPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW 408
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 67.8 bits (164), Expect = 2e-11 Identities = 41/117 (35%), Positives = 62/117 (52%) Frame = +1 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 ++ AQ +I AG +T+ V+ + M L +PD+ KLQ E+ + +P K D + Sbjct: 293 ELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQ 351 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + YL V+ ETLRL P + + + D ING IP G V++ S A+ RDP W Sbjct: 352 MEYLDMVVNETLRL-FPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW 407
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 67.8 bits (164), Expect = 2e-11 Identities = 49/203 (24%), Positives = 89/203 (43%), Gaps = 22/203 (10%) Frame = +1 Query: 10 ELLKLDIIRWMVCGRARRVNKMWDDLLESLI--HEHESKPAPALGDDTDYIHDLLSIQKE 183 E+++ +++ + G R++N++ D + + I E + K +G+ D+I L + E Sbjct: 229 EIIRQILLKNLKVGSFRKINEITLDAIHNRIKQREEDQKNGIEIGEPADFIDLFLDAKAE 288 Query: 184 --------------------YNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDL 303 LT E++ Q + AG DT+ + + YA L +P++ Sbjct: 289 DVEHFGENNGDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEI 348 Query: 304 MTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVING 483 KLQ EV P + V D L+ L Y++ V KE LRL+ M + + Sbjct: 349 QKKLQEEVNRECPNPE--VTIDQLSKLKYMECVFKEALRLYPLGAFANSRRCMRNTKLGN 406 Query: 484 YTIPSGTRVIVNSRAIARDPSSW 552 + GT + V++ + DP+ W Sbjct: 407 MKVEVGTMIQVDTWTLHTDPNIW 429
>CP1A1_RAT (P00185) Cytochrome P450 1A1 (EC 1.14.14.1) (CYP1A1) (CYPIA1)| (P450-C) (P450MT2) [Contains: Cytochrome P450MT2A; Cytochrome P450MT2B] Length = 524 Score = 67.4 bits (163), Expect = 3e-11 Identities = 48/169 (28%), Positives = 79/169 (46%), Gaps = 6/169 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHD-----LLSIQKEYNLTREQVKAQLVI 225 +NK + ++ LI EH + + D TD + + L L+ ++V + Sbjct: 258 LNKKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRRLDENANVQLSDDKVITIVFD 317 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ NP + K+Q E+ + I + + + D L YL+A I Sbjct: 318 LFGAGFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQPRLSDR-PQLPYLEAFI 376 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ET R P +PH + D +NG+ IP G V VN + D W Sbjct: 377 LETFRHSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNHDQELW 425
>CP10_LYMST (P48416) Cytochrome P450 10 (EC 1.14.-.-) (CYPX)| Length = 545 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/155 (29%), Positives = 75/155 (48%) Frame = +1 Query: 82 DLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIV 261 D+ SL+ E K P + T +H + + +++ ++V +V + A +T+ Sbjct: 303 DIGRSLV---EKKWHPCKMEVTQNLHLISYLVNNGSMSTKEVTGLIVDLMLAAVETTSSA 359 Query: 262 MEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPL 441 + + L +NP + KL E+ + K + +DL L +KAV+KETLRL+ P Sbjct: 360 TVWCLYNLAKNPQVQEKLFQEITEAQAKNNGTISAEDLCKLPMVKAVVKETLRLY-PITY 418 Query: 442 LVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPS 546 D + GYTIP+GT V N + RDPS Sbjct: 419 STSRNIAEDMELGGYTIPAGTHVQANLYGMYRDPS 453
>CP1A1_LIZAU (O42231) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 67.4 bits (163), Expect = 3e-11 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N + ++ ++ EH + + D TD + D +K Q+ + V+ Sbjct: 259 INDRFISFVQKIVSEHYATFNKDNIRDITDSLIDHCEDRKLDENANVQMSDEKVVGIVND 318 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ P++ +L E++ ++ + V+ D N+L L+A I Sbjct: 319 LFGAGLDTISTALSWSVMYLVAYPEIQERLYQELKENVGLDRTPVLSDR-NNLPLLEAFI 377 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH D +NGY IP T V +N I DP W+ Sbjct: 378 LEIFRHSSFLPFTIPHCTTKDTSLNGYYIPKDTCVFINQWQINHDPELWK 427
>CP1B1_HUMAN (Q16678) Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1)| Length = 543 Score = 67.4 bits (163), Expect = 3e-11 Identities = 37/121 (30%), Positives = 61/121 (50%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L E V A + +FGA DT +++ + + PD+ T++QAE+ + + + + D Sbjct: 315 LDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGD 374 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 N L Y+ A + E +R P+ +PH A+ + GY IP T V VN ++ DP Sbjct: 375 QPN-LPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLK 433 Query: 550 W 552 W Sbjct: 434 W 434
>CP21A_BOVIN (P00191) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 496 Score = 67.4 bits (163), Expect = 3e-11 Identities = 52/166 (31%), Positives = 75/166 (45%), Gaps = 7/166 (4%) Frame = +1 Query: 79 DDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQKEYN----LTREQVKAQLVIMFGAGT 243 D ++E + H ES A D TDY+ + Q+ L V +V +F GT Sbjct: 233 DHMVEKQLTRHKESMVAGQWRDMTDYMLQGVGRQRVEEGPGQLLEGHVHMSVVDLFIGGT 292 Query: 244 DTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHM--VIEDDLNHLAYLKAVIKETL 417 +T+ + +A+A L+ +P++ +LQ E+ + G V D L L A I E L Sbjct: 293 ETTASTLSWAVAFLLHHPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVL 352 Query: 418 RLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 RL PL +PH I GY IP G VI N + D + WE Sbjct: 353 RLRPVVPLALPHRTTRPSSIFGYDIPEGMVVIPNLQGAHLDETVWE 398
>CP17A_PIG (P19100) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 67.4 bits (163), Expect = 3e-11 Identities = 41/121 (33%), Positives = 64/121 (52%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ + A + +FGAG +TS V+++ +A L+ P L K+Q + +I + I D Sbjct: 287 LSDRHMLATVADIFGAGVETSASVVKWIVAFLLHYPLLRKKIQDAIDQNIGFNRAPSISD 346 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 N L L+A I+E LR +P L+PH A+ D I +TI T V+VN A+ + Sbjct: 347 R-NQLVLLEATIREVLRFRPVSPTLIPHRAIIDSSIGEFTIDKDTDVVVNLWALHHNEKE 405 Query: 550 W 552 W Sbjct: 406 W 406
>CP21A_MOUSE (P03940) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 487 Score = 67.4 bits (163), Expect = 3e-11 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 5/173 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQK----EYNLTREQVKAQ 216 + +++ + D +++ + +H +S A D DY+ + Q+ E L V Sbjct: 220 KLKQIQESRDHIVKQQLKQHKDSLVAGQWKDMIDYMLQGVEKQRDGKDEERLHEGHVHMS 279 Query: 217 LVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 +V +F GT+T+ + +A+A L+ +P++ +LQ E+ + G ++ + + L L Sbjct: 280 VVDLFIGGTETTATTLSWAVAFLLHHPEIQKRLQEELDLKLGPGSQLLYRNRMQ-LPLLM 338 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 A I E LRL PL +PH A I+GY IP +I N + D WE Sbjct: 339 ATIAEVLRLRPVVPLALPHRATRASSISGYDIPKDMVIIPNIQGANLDEMVWE 391
>CP2CT_MOUSE (Q64458) Cytochrome P450 2C29 (EC 1.14.14.1) (CYPIIC29) (P-450| MUT-2) (Aldehyde oxygenase) Length = 490 Score = 67.4 bits (163), Expect = 3e-11 Identities = 46/167 (27%), Positives = 80/167 (47%), Gaps = 6/167 (3%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN------LTREQVKAQL 219 + N + LLE + E K + + + D+I L QK+ N + E + + + Sbjct: 235 KNFNYLKSYLLEKI---KEHKESLDVTNPRDFIDYYLIKQKQVNHIEQSEFSLENLASTI 291 Query: 220 VIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 +FGAGT+T+ + YA+ L++ PD+ K+Q E+ + + + ++D +H+ Y A Sbjct: 292 NDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSPCMQDR-SHMPYTDA 350 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 +I E R P +PH D Y IP GT VI + ++ D Sbjct: 351 MIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHD 397
>CP1A1_CANFA (P56590) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (DAH1)| Length = 524 Score = 67.0 bits (162), Expect = 3e-11 Identities = 45/169 (26%), Positives = 81/169 (47%), Gaps = 6/169 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHD-----LLSIQKEYNLTREQVKAQLVI 225 +NK + ++ ++ EH ++ + D TD + + L L+ E++ ++ Sbjct: 258 LNKRFYSFMQKMVKEHYKTFEKGQIRDVTDSLIEHCQDKRLDENANIQLSDEKIVNVVLD 317 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ NP++ K+Q E+ + I + + + D L Y++A I Sbjct: 318 LFGAGFDTVTTAISWSLLYLVTNPNVQKKIQKELDTVIGRARQPRLSDR-PQLPYMEAFI 376 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ET R P +PH D ++G+ IP G V VN I D W Sbjct: 377 LETFRHASFVPFTIPHSTTRDTSLSGFYIPKGRCVFVNQWQINHDQKLW 425
>CP2CB_RAT (P08683) Cytochrome P450 2C11 (EC 1.14.14.1) (CYPIIC11)| (P-450(M-1)) (P450H) (P450-UT-A) (UT-2) Length = 500 Score = 67.0 bits (162), Expect = 3e-11 Identities = 40/122 (32%), Positives = 63/122 (51%) Frame = +1 Query: 175 QKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 Q E+ L E + A + MFGAGT+T+ + Y + L+++ D+ K+Q E+ I + + Sbjct: 279 QSEFTL--ESLVATVTDMFGAGTETTSTTLRYGLLLLLKHVDVTAKVQEEIERVIGRNRS 336 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 ++ D + + Y AV+ E R P +PHL D Y IP GT VIV+ +I Sbjct: 337 PCMK-DRSQMPYTDAVVHEIQRYIDLVPTNLPHLVTRDIKFRNYFIPKGTNVIVSLSSIL 395 Query: 535 RD 540 D Sbjct: 396 HD 397
>CP1B1_RAT (Q64678) Cytochrome P450 1B1 (EC 1.14.14.1) (CYPIB1) (P450RAP)| Length = 543 Score = 67.0 bits (162), Expect = 3e-11 Identities = 44/159 (27%), Positives = 74/159 (46%) Frame = +1 Query: 82 DLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIV 261 D++++ I E K A GD D L E V A + +FGA DT Sbjct: 291 DMMDAFILSAEKK---ATGDPGD---------SPSGLDLEDVPATITDIFGASQDTLSTA 338 Query: 262 MEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPL 441 + + + + PD+ ++QAE+ + + + + D N L Y+ A + E++R P+ Sbjct: 339 LLWLLILFTRYPDVQARVQAELDQVVGRDRLPCMSDQPN-LPYVMAFLYESMRFTSFLPV 397 Query: 442 LVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWES 558 +PH A+ + GY IP T V VN ++ DP+ W + Sbjct: 398 TLPHATTANTFVLGYYIPKNTVVFVNQWSVNHDPAKWSN 436
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 67.0 bits (162), Expect = 3e-11 Identities = 39/121 (32%), Positives = 63/121 (52%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ ++ AQ +I AG +T+ ++ + + L +PD+ KLQ E+ ++P K D Sbjct: 291 LSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALP-NKAPPTYD 349 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 + + YL V+ ETLRL+ P + + D ING IP G+ VI+ S + DP Sbjct: 350 TVMAMEYLDMVLNETLRLY-PITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQH 408 Query: 550 W 552 W Sbjct: 409 W 409
>CP2CP_MESAU (Q08078) Cytochrome P450 2C25 (EC 1.14.14.1) (CYPIIC25) (P450 HSM1)| Length = 490 Score = 67.0 bits (162), Expect = 3e-11 Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 5/166 (3%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLL-----SIQKEYNLTREQVKAQLV 222 + VN + +LE + ES D DY L + Q E++L E + + Sbjct: 235 KNVNYLKKYILEKIEEHQESLDIENPRDFIDYYLIKLKQANHNQQSEFSL--ENLTTTVS 292 Query: 223 IMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 +FGAGT+T+ + YA+ L+++P + K+Q E+ + + + ++D +H+ Y A+ Sbjct: 293 DLFGAGTETTSTTLRYALLLLLKHPHVTAKVQEEIDQVVGRHRKPCMQDR-SHMPYTDAM 351 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 I E R P+ +PH D Y IP GT VI + ++ D Sbjct: 352 IHEVQRFIDLIPISLPHAVTCDIKFRDYFIPKGTTVITSLSSVLHD 397
>CP2DG_CAVPO (Q64403) Cytochrome P450 2D16 (EC 1.14.14.1) (CYPIID16)| Length = 500 Score = 66.6 bits (161), Expect = 4e-11 Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 5/162 (3%) Frame = +1 Query: 85 LLESLIHEHESKPAPALG--DDTD-YIHDLLSIQ--KEYNLTREQVKAQLVIMFGAGTDT 249 L + L+ EH + AP D TD ++ ++ Q E + E ++ + +FGAG T Sbjct: 253 LNDKLLAEHNTGWAPDQPPRDLTDAFLTEMHKAQGNSESSFNDENLRLLVSDLFGAGMVT 312 Query: 250 SYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHM 429 + + + +A+ ++ +PD+ +Q E+ I + + + D H+ + AVI E R Sbjct: 313 TSVTLSWALLLMILHPDVQRHVQEEIDEVIGQVRCPEMADQA-HMPFTNAVIHEVQRFAD 371 Query: 430 PAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 P+ VPH+ D + G+ IP GT + N ++ +D + WE Sbjct: 372 IVPMGVPHMTSRDTEVQGFLIPKGTMLFTNLSSVLKDETVWE 413
>CP2J3_RAT (P51590) Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3)| Length = 502 Score = 66.6 bits (161), Expect = 4e-11 Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 6/141 (4%) Frame = +1 Query: 148 DYIHDLLSIQKEY------NLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMT 309 D+I L +Y + E + + +F AGT+T+ + +A+ + P++ Sbjct: 276 DFIDAFLKEMAKYPDKTTTSFNEENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQE 335 Query: 310 KLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYT 489 K+QAE+ I +G+ + D + + Y AVI E R+ P VP D + G+ Sbjct: 336 KMQAEIDRVIGQGRQPNLADR-DSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFN 394 Query: 490 IPSGTRVIVNSRAIARDPSSW 552 +P GT ++ N A+ RDP W Sbjct: 395 LPKGTMILTNLTALHRDPKEW 415
>CP2D6_HUMAN (P10635) Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1)| (Debrisoquine 4-hydroxylase) Length = 497 Score = 66.6 bits (161), Expect = 4e-11 Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 7/178 (3%) Frame = +1 Query: 43 VCGRARRVNKMWDDLLESLIHEHESK--PAPALGDDTDYIHDLLSIQK-----EYNLTRE 201 + G+ R K + L+ L+ EH PA D T+ L ++K E + E Sbjct: 236 LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAF--LAEMEKAKGNPESSFNDE 293 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 ++ + +F AG T+ + + + ++ +PD+ ++Q E+ I + + + D H Sbjct: 294 NLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-H 352 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 + Y AVI E R PL V H+ D + G+ IP GT +I N ++ +D + WE Sbjct: 353 MPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 66.6 bits (161), Expect = 4e-11 Identities = 41/142 (28%), Positives = 69/142 (48%), Gaps = 2/142 (1%) Frame = +1 Query: 124 APALGDDTDYIHDLLSIQKEYN--LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNP 297 AP+ ++ LLS+ + L+ E ++ ++ G DT+ + +++ L NP Sbjct: 290 APSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNP 349 Query: 298 DLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVI 477 ++ K+ E+ K +DL L YL+ VIKETLRL PL ++ DC + Sbjct: 350 EVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVS-EDCEV 408 Query: 478 NGYTIPSGTRVIVNSRAIARDP 543 GY + GT ++ A+ RDP Sbjct: 409 AGYRVLKGTEAVIIPYALHRDP 430
>CP1A2_MACFA (O77809) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 66.2 bits (160), Expect = 6e-11 Identities = 47/171 (27%), Positives = 79/171 (46%), Gaps = 4/171 (2%) Frame = +1 Query: 52 RARRVNKMWDDLLESLIHEH-ESKPAPALGDDTDYI--HDLLSIQKEYNLTREQVKAQLV 222 R + N+ + L+ + EH + ++ D T + H + NL ++ LV Sbjct: 251 RFKAFNQRFRRFLQKTVQEHYQDFDKNSVQDITGALFKHSKKGPRASGNLIPQEKIVNLV 310 Query: 223 I-MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKA 399 +FGAG DT + +++ L+ P++ K+Q E+ + I +G+ + D L YL+A Sbjct: 311 NDIFGAGFDTIATAISWSLMYLVTKPEIQRKIQKELDAVIGRGRRPRLSDR-PQLPYLEA 369 Query: 400 VIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 I ET R P +PH D +NG+ IP V +N + DP W Sbjct: 370 FILETFRHSSFVPFTIPHSTTRDTTLNGFYIPRECCVFINQWQVNHDPQLW 420
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 66.2 bits (160), Expect = 6e-11 Identities = 41/131 (31%), Positives = 70/131 (53%) Frame = +1 Query: 160 DLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSI 339 ++L + K +LT +++ QL + AG DT+ + + Y+ L +P++ KLQ EV Sbjct: 303 EVLKVDK--HLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDREC 360 Query: 340 PKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVN 519 P + V D L+ L YL+ V+KE LRL+ A L+ + + G I +GT + V+ Sbjct: 361 PDPE--VTFDQLSKLKYLECVVKEALRLYPLASLVHNRKCLKTTNVLGMEIEAGTNINVD 418 Query: 520 SRAIARDPSSW 552 + ++ DP W Sbjct: 419 TWSLHHDPKVW 429
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 66.2 bits (160), Expect = 6e-11 Identities = 38/117 (32%), Positives = 61/117 (52%) Frame = +1 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 ++ AQ +I AG +T+ V+ + + L +PD+ KLQ E+ + +P K D + Sbjct: 294 ELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLP-NKAPPTYDAVVQ 352 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + YL V+ ETLRL P + + D ING IP G+ V++ + A+ DP W Sbjct: 353 MEYLDMVVNETLRL-FPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYW 408
>CP1A1_SPAAU (O42457) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 66.2 bits (160), Expect = 6e-11 Identities = 44/170 (25%), Positives = 80/170 (47%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N ++ ++ ++ EH + + D TD + D +K + Q+ + V+ Sbjct: 259 INDRFNAFVQKIVSEHYTTFDKDNIRDITDSLIDHCEDRKLDENSNVQMSDEKVVGIVND 318 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ P++ +L E++ S+ + + D L +L+A I Sbjct: 319 LFGAGFDTISTALSWSVMYLVAYPEIQERLYQEMKESVGLDRTPCLSDKPK-LPFLEAFI 377 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH + D +NGY IP T V +N I DP W+ Sbjct: 378 LEIFRHSSFLPFTIPHCSSKDTSLNGYFIPKDTCVFINQWQINHDPELWK 427
>CP1A1_OPSTA (Q92095) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 66.2 bits (160), Expect = 6e-11 Identities = 45/170 (26%), Positives = 78/170 (45%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N +D ++ ++ EH + + D TD + D +K QV + ++ Sbjct: 259 INDRFDKFVKKIVSEHYATYNKDNIRDITDSLIDHCEDRKLDENCNVQVSDEKIVGIVND 318 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ P++ +L E++ S+ + M + D L +L A I Sbjct: 319 LFGAGFDTVSTGLSWSVMYLVAYPEIQERLYQEIKDSVGT-ERMPLLSDRPSLPFLDAFI 377 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH + +NGY IP T V +N I DP W+ Sbjct: 378 LEIFRHSSFLPFTIPHCTTKNTSLNGYFIPKDTCVFINQWQINHDPELWK 427
>CP2C4_RABIT (P11371) Cytochrome P450 2C4 (EC 1.14.14.1) (CYPIIC4) (Progesterone| 21-hydroxylase) (P450 PBC4) (P1-88) Length = 487 Score = 66.2 bits (160), Expect = 6e-11 Identities = 40/134 (29%), Positives = 70/134 (52%), Gaps = 4/134 (2%) Frame = +1 Query: 163 LLSIQKEYNLTREQVKAQLVI----MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVR 330 L+ ++KE NL E LVI +FGAGT+T+ + Y++ L+++P++ ++Q E+ Sbjct: 268 LIKMEKENNL--EFTLGSLVIAVFDLFGAGTETTSTTLRYSLLLLLKHPEVAARVQEEIE 325 Query: 331 SSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRV 510 I + + ++D +H+ Y AVI E R P +PH D Y IP GT + Sbjct: 326 RVIGRHRSPCMQDR-SHMPYTDAVIHEIQRFIDLLPTNLPHAVTRDVKFRNYFIPKGTDI 384 Query: 511 IVNSRAIARDPSSW 552 I + ++ D ++ Sbjct: 385 ITSLTSVLHDEKAF 398
>CP2CJ_HUMAN (P33261) Cytochrome P450 2C19 (EC 1.14.13.80) ((R)-limonene| 6-monooxygenase) (EC 1.14.13.48) ((S)-limonene 6-monooxygenase) (EC 1.14.13.49) ((S)-limonene 7-monooxygenase) (CYPIIC19) (P450-11A) (Mephenytoin 4-hydroxylase) (CYPIIC17) (P450-254C Length = 490 Score = 66.2 bits (160), Expect = 6e-11 Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 6/162 (3%) Frame = +1 Query: 73 MWDDLLESLIHEHESKPAPALGDDTDYIHD-LLSIQKE-YNLTREQVKAQLVI----MFG 234 M D+LE + ES + + D+I L+ ++KE N E LVI + G Sbjct: 240 MESDILEKVKEHQESMD---INNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLG 296 Query: 235 AGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKET 414 AGT+T+ + YA+ L+++P++ K+Q E+ + + + ++D H+ Y AV+ E Sbjct: 297 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDR-GHMPYTDAVVHEV 355 Query: 415 LRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 R P +PH D Y IP GT ++ + ++ D Sbjct: 356 QRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHD 397
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 65.9 bits (159), Expect = 8e-11 Identities = 42/117 (35%), Positives = 59/117 (50%) Frame = +1 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 ++ AQ +I+ A DT+ + + M L +PD+ KLQ E+ + +P K V D L Sbjct: 294 ELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQ 352 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + YL V+ ETLRL P V + D ING IP G V+V A+ DP W Sbjct: 353 MEYLDMVVNETLRL-FPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW 408
>CP1A1_CAVPO (Q06367) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 516 Score = 65.9 bits (159), Expect = 8e-11 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 6/169 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N+ + ++ +I EH ++ + D TD + + +K Q+ Q +I Sbjct: 250 LNRRFSVFIQKMIKEHYKTFEKGHIRDITDSLIEHCQDRKLDKNANIQISDQKIIGIVLD 309 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ NP + K+Q E+ + I + + + D L Y++A I Sbjct: 310 LFGAGFDTITTAISWSLLYLVMNPRIQKKIQEELDTVIGRERQPQLADRPK-LPYMEAFI 368 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 E R P +PH D +NG+ IP G + VN I D W Sbjct: 369 SEVFRYSSFMPFTIPHSTTKDTSLNGFYIPKGCCIFVNQWQINHDQKLW 417
>CP11B_RANCA (Q92104) Cytochrome P450 11B, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB) (P450C11) (Steroid 11-beta-hydroxylase) (P-450(11 beta,aldo)) Length = 517 Score = 65.9 bits (159), Expect = 8e-11 Identities = 41/143 (28%), Positives = 72/143 (50%) Frame = +1 Query: 133 LGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTK 312 LG + Y + + + L + +KA + + G DT+ + + + + L +NP + + Sbjct: 297 LGQERGYSGIMAELLLQAELPLDSIKANITELMAGGVDTTAMPLLFTLFELARNPSVQRE 356 Query: 313 LQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTI 492 L+ E+R + + + + LN L LK IKETLRL+ P + V + D V++ Y I Sbjct: 357 LREEIRKAEAQNPN-DLNQLLNSLPLLKGAIKETLRLY-PVGITVQRHLIKDIVLHNYHI 414 Query: 493 PSGTRVIVNSRAIARDPSSWESA 561 P+GT V V + R P ++ A Sbjct: 415 PAGTLVQVGLYPMGRSPLLFQDA 437
>CP2DI_RAT (Q64680) Cytochrome P450 2D18 (EC 1.14.14.1) (CYPIID18) (P450| 2D-29/2D-35) Length = 500 Score = 65.9 bits (159), Expect = 8e-11 Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 5/189 (2%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK- 180 FP LL + + V + M D+LL H+ PA D TD L ++K Sbjct: 230 FPMLLHIPGLLGKVFSGKKAFVAMLDELLTE--HKVTWDPAQPPRDLTDAF--LAEVEKA 285 Query: 181 ----EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKG 348 E + E ++ + +F AG T+ + +A+ ++ PD+ ++Q E+ I + Sbjct: 286 KGNPESSFNDENLRVVVADLFMAGMVTTSTTLTWALLFMILRPDVQCRVQQEIDEVIGQV 345 Query: 349 KHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRA 528 + + D + + AVI E R PL VPH D + G+ IP GT +I+N + Sbjct: 346 RRPEMADQAR-MPFTNAVIHEVQRFADILPLGVPHKTSRDIEVQGFLIPKGTTLIINLSS 404 Query: 529 IARDPSSWE 555 + +D + WE Sbjct: 405 VLKDETVWE 413
>CP1A1_SHEEP (P56591) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-C)| (P4501A1) Length = 519 Score = 65.9 bits (159), Expect = 8e-11 Identities = 39/122 (31%), Positives = 62/122 (50%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ E++ ++ +FGAG DT + +++ L+ +P + K+Q E+ + I + + + D Sbjct: 309 LSDEKIINVVMDLFGAGFDTVTTAISWSLLYLVTSPRVQKKIQEELDTVIGRARWPQLSD 368 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 L YL+A I ET R P +PH D +NG+ IP G V VN I D Sbjct: 369 R-PQLPYLEAFILETFRHSSFVPFTIPHSTTRDTNLNGFYIPKGXCVFVNQWQINHDQKL 427 Query: 550 WE 555 WE Sbjct: 428 WE 429
>CP2E1_MOUSE (Q05421) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| (P450-ALC) Length = 493 Score = 65.9 bits (159), Expect = 8e-11 Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 5/130 (3%) Frame = +1 Query: 139 DDTDYIHDLLSIQKEYN-----LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDL 303 D TD + L+ ++KE + T E + L +F AGT+T+ + Y + LM+ P++ Sbjct: 264 DVTDCL--LIEMEKEKHSQEPMYTMENISVTLADLFFAGTETTSTTLRYGLLILMKYPEI 321 Query: 304 MTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVING 483 KL E+ I + + D +N + Y+ AV+ E R P +PH A D V G Sbjct: 322 EEKLHEEIDRVIGPSRAPAVRDRMN-MPYMDAVVHEIQRFINLVPSNLPHEATRDTVFRG 380 Query: 484 YTIPSGTRVI 513 Y IP GT VI Sbjct: 381 YVIPKGTVVI 390
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 65.9 bits (159), Expect = 8e-11 Identities = 38/121 (31%), Positives = 63/121 (52%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ ++ AQ +I AG +T+ + + + L +PD+ KLQ E+ ++P K D Sbjct: 291 LSDMEITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALP-NKAPPTYD 349 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 + + YL V+ ETLRL+ P + + D +NG IP G+ V++ S A+ DP Sbjct: 350 TVMEMEYLDMVLNETLRLY-PIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQH 408 Query: 550 W 552 W Sbjct: 409 W 409
>CP27A_MOUSE (Q9DBG1) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 65.9 bits (159), Expect = 8e-11 Identities = 43/132 (32%), Positives = 69/132 (52%) Frame = +1 Query: 151 YIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVR 330 Y+H LL+ E T+E + ++ AG DT+ + +A+ L ++P++ L EV Sbjct: 312 YLHFLLT--NELLSTQETIGTFPELLL-AGVDTTSNTLTWALYHLSKSPEIQEALHKEVT 368 Query: 331 SSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRV 510 +P GK + D H+ LKAVIKETLRL+ P + + ING+ P T+ Sbjct: 369 GVVPFGK-VPQHKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQF 427 Query: 511 IVNSRAIARDPS 546 ++ ++RDPS Sbjct: 428 VLCHYVVSRDPS 439
>CP1A2_CAVPO (Q64391) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 10/173 (5%) Frame = +1 Query: 67 NKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI------- 225 NK + L+ + EH D +++ D+ S +++ V L+ Sbjct: 257 NKRFLQFLQKTVQEHYQD------FDKNHVQDIASALFKHSEESPHVNGDLIPRKKIVNL 310 Query: 226 ---MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLK 396 +FGAG DT + +++ L+ P++ K+ E+ + I + + + D L Y++ Sbjct: 311 VNDIFGAGFDTVTTAISWSLLYLVTKPEIQKKIHKELDAVIGRDRKPRLADR-PQLPYME 369 Query: 397 AVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 A I E R P +PH D ++NG+ IP V +N + DP WE Sbjct: 370 AFILEVFRYSSFLPFTIPHCTTRDTILNGFYIPKDRCVFINQWQVNHDPKQWE 422
>CP1A2_CALJA (O77810) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/131 (29%), Positives = 62/131 (47%) Frame = +1 Query: 160 DLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSI 339 DL+ +K NL + +FGAG DT + +++ L+ P++ K+Q E+ + I Sbjct: 299 DLIPQEKIVNLVND--------IFGAGFDTITTAISWSLMYLVTKPEIQRKIQKELDTVI 350 Query: 340 PKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVN 519 +G+ + D L YL+A I ET R P +PH D + G+ IP V +N Sbjct: 351 GRGRRPRLSDR-PQLPYLEAFILETFRHSSFVPFTIPHSTTRDTTLKGFYIPKECCVFIN 409 Query: 520 SRAIARDPSSW 552 + DP W Sbjct: 410 QWQVNHDPQLW 420
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/121 (33%), Positives = 63/121 (52%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ +++ AQ VI AG +T+ + + + L +PD+ KLQ E+ ++ P K D Sbjct: 290 LSDQELMAQSVIFIFAGYETTSNTLSFLLYILATHPDVQQKLQEEIDATFP-NKAPPTYD 348 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 L + YL V+ ETLR+ P + + L D I+G +IP GT V V + RDP Sbjct: 349 VLAQMEYLDMVVNETLRM-FPIAVRLDRLCKKDVEIHGVSIPKGTAVTVPIFVLHRDPQL 407 Query: 550 W 552 W Sbjct: 408 W 408
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 65.5 bits (158), Expect = 1e-10 Identities = 40/121 (33%), Positives = 62/121 (51%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ ++ AQ +I AG +TS + M L +PD+ KL E+ ++P K D Sbjct: 290 LSDVEILAQSIIFIFAGYETSSSTLSCIMYSLATHPDVQKKLHQEIDKTLPN-KAFPTYD 348 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 + + YL V+ ETLRL+ P + ++ D ING + P GT V++ S A+ RD Sbjct: 349 VMMEMEYLDMVVNETLRLY-PVANRIERMSKKDFEINGMSFPKGTLVMIPSFALHRDSKY 407 Query: 550 W 552 W Sbjct: 408 W 408
>CP137_MYCTU (O69653) Putative cytochrome P450 137 (EC 1.14.-.-)| Length = 476 Score = 65.5 bits (158), Expect = 1e-10 Identities = 49/167 (29%), Positives = 86/167 (51%), Gaps = 2/167 (1%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN--LTREQVKAQLVIMFG 234 R N DD++ +LI + + P LG+ D + L+S + E L+ +++ L+ + Sbjct: 243 RANTEIDDVVMALIAQRRADPR--LGERHDVLSLLVSARGESGEQLSDSEIRDDLITLVL 300 Query: 235 AGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKET 414 AG +T+ + +A L+ +PD + +++AE ++ G+ A+ AVI ET Sbjct: 301 AGHETTATTLAWAFDLLLHHPDALRRVRAE---AVGGGE-----------AFTTAVINET 346 Query: 415 LRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 LR+ PAPL +A I GY + +GTR++V+ AI R +E Sbjct: 347 LRVRPPAPLTA-RVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVYE 392
>C49A1_DROME (Q9V5L3) Probable cytochrome P450 49a1 (EC 1.14.-.-) (CYPXLIXA1)| Length = 589 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/107 (32%), Positives = 57/107 (53%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +F G DT+ + + +L +NPD KL E++ P + + ++ L + YL+A + Sbjct: 386 LFLVGVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRACV 445 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPS 546 KETLR+ P + +D VINGY +P GT VI ++ DP+ Sbjct: 446 KETLRMR-PVVIANGRSLQSDAVINGYHVPKGTHVIFPHLVVSNDPA 491
>CP21A_RAT (Q64562) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 493 Score = 65.5 bits (158), Expect = 1e-10 Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 4/161 (2%) Frame = +1 Query: 85 LLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN----LTREQVKAQLVIMFGAGTDTS 252 +++ L +S A D DY+ + Q++ L V +V +F GT+T+ Sbjct: 235 VMQELKRHKDSLVAGQWKDMIDYMLQGVEKQRDARDPGQLHERHVHMSVVDLFVGGTETT 294 Query: 253 YIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMP 432 + +A+A L+ +P++ +LQ E+ + ++ ++ + L L A I E LRL Sbjct: 295 AATLSWAVAFLLHHPEIQKRLQEELDLKLAPSSQLLYKNRMQ-LPLLMATIAEVLRLRPV 353 Query: 433 APLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 P+ +PH A I+GY IP T +I N + D WE Sbjct: 354 VPMALPHRATKASSISGYDIPKDTIIIPNIQGANLDEMVWE 394
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/142 (28%), Positives = 69/142 (48%), Gaps = 2/142 (1%) Frame = +1 Query: 124 APALGDDTDYIHDLLSIQKEYN--LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNP 297 AP+ ++ LLS+ + L+ E ++ ++ G DT+ + +++ L NP Sbjct: 290 APSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGCNP 349 Query: 298 DLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVI 477 ++ K+ E+ K +DL L YL+ VIKETLRL PL ++ DC + Sbjct: 350 EVQQKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVS-EDCEV 408 Query: 478 NGYTIPSGTRVIVNSRAIARDP 543 GY + GT ++ A+ RDP Sbjct: 409 AGYRVLKGTEAVIIPYALHRDP 430
>CP239_MOUSE (P56656) Cytochrome P450 2C39 (EC 1.14.14.1) (CYPIIC39)| Length = 490 Score = 65.1 bits (157), Expect = 1e-10 Identities = 46/158 (29%), Positives = 71/158 (44%), Gaps = 6/158 (3%) Frame = +1 Query: 85 LLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN------LTREQVKAQLVIMFGAGTD 246 LLE + ES D DY L QK+ N + E + + +F AGT+ Sbjct: 244 LLEKIKEHQESLDVTNPRDFIDYY---LIKQKQANHIQQAEFSLENLACTINNLFAAGTE 300 Query: 247 TSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLH 426 T+ + YA+ LM+ PD+ K+Q E+ I + + ++ D NH+ Y A+I E R Sbjct: 301 TTSTTLRYALLLLMKYPDVTAKVQEEIDHVIGRHRSPCMQ-DRNHMPYTDAMIHEVQRFI 359 Query: 427 MPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 P +P D Y IP GT V+ + ++ D Sbjct: 360 NLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHD 397
>CP238_MOUSE (P56655) Cytochrome P450 2C38 (EC 1.14.14.1) (CYPIIC38)| Length = 490 Score = 65.1 bits (157), Expect = 1e-10 Identities = 37/122 (30%), Positives = 62/122 (50%) Frame = +1 Query: 175 QKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 Q EY+L E + + +F AGT+T+ + YA+ LM+ PD+ K+Q E+ + + + Sbjct: 279 QAEYSL--ENLVCTINNLFAAGTETTSTTLRYALLLLMKYPDVTAKVQEEIDHVVGRHRS 336 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 ++D +H+ Y A+I E R P +PH D Y IP GT V+ + ++ Sbjct: 337 PCMQDR-SHMPYTDAMIHEVQRFINLVPNNLPHAVTCDIKFRNYIIPKGTTVVTSLTSVL 395 Query: 535 RD 540 D Sbjct: 396 HD 397
>CP1A1_MOUSE (P00184) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1)| Length = 524 Score = 65.1 bits (157), Expect = 1e-10 Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 6/169 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEH-ESKPAPALGDDTDYIHDLLSIQK-----EYNLTREQVKAQLVI 225 +N + ++ LI EH + + D TD + + +K L+ ++V ++ Sbjct: 258 LNDKFYSFMKKLIKEHYRTFEKGHIRDITDSLIEHCQDRKLDENANVQLSDDKVITIVLD 317 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ NP + K+Q E+ + I + + + D L YL+A I Sbjct: 318 LFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQPRLSDR-PQLPYLEAFI 376 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ET R P +PH D +NG+ IP G V VN + D W Sbjct: 377 LETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELW 425
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 65.1 bits (157), Expect = 1e-10 Identities = 39/117 (33%), Positives = 60/117 (51%) Frame = +1 Query: 202 QVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNH 381 ++ AQ +I AG +T+ + + M L +PD+ KLQ E+ + +P K D + Sbjct: 294 ELVAQSIIFIFAGYETTSSTLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPATYDTVLQ 352 Query: 382 LAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + YL V+ ETLRL P + + + D ING IP G V++ S A+ DP W Sbjct: 353 MEYLDMVVNETLRL-FPLAMRLERVCKKDVEINGVFIPKGVVVMIPSYALHYDPKYW 408
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 65.1 bits (157), Expect = 1e-10 Identities = 39/121 (32%), Positives = 63/121 (52%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ ++ AQ + AG +T+ + + M L +PD+ KLQ E+ ++P K D Sbjct: 290 LSDVEILAQSIFFIVAGYETTSSTLCFIMYSLATHPDVQKKLQQEIDKTLP-NKAFPTYD 348 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 + + YL V+ ETLRL+ P + ++ D ING + P GT V++ S A+ RD Sbjct: 349 VMMEMEYLDMVVNETLRLY-PVTNRIERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKY 407 Query: 550 W 552 W Sbjct: 408 W 408
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 65.1 bits (157), Expect = 1e-10 Identities = 49/168 (29%), Positives = 75/168 (44%) Frame = +1 Query: 49 GRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIM 228 GR + K D L+ +I SK + H LS ++ AQ +I Sbjct: 259 GRLKETQKHRVDFLQLMIDSQNSKDSET--------HKALSDL--------ELMAQSIIF 302 Query: 229 FGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIK 408 AG +T+ V+ + + L +PD+ K+Q E+ + +P K D + L YL V+ Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTYDTVLQLEYLDMVVN 361 Query: 409 ETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ETLRL P + + + D ING IP G V++ S + DP W Sbjct: 362 ETLRL-FPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYW 408
>CP1A1_BALAC (Q3LFU0) Cytochrome P450 1A1 (EC 1.14.14.1)| Length = 516 Score = 65.1 bits (157), Expect = 1e-10 Identities = 38/122 (31%), Positives = 61/122 (50%) Frame = +1 Query: 190 LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIED 369 L+ E++ ++ +FGAG DT + +++ L+ +P + K+Q E+ + I + + D Sbjct: 306 LSDEKIVNVVMDLFGAGFDTVTTAISWSLMYLVTSPSVQKKIQEELDTVIGSARQPRLSD 365 Query: 370 DLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSS 549 L YL+A I ET R P +PH D +NG+ IP G V VN I D Sbjct: 366 R-PRLPYLEAFILETFRHSSFLPFTIPHSTTRDTSLNGFYIPKGRCVFVNQWQINHDQKL 424 Query: 550 WE 555 W+ Sbjct: 425 WD 426
>CP1A2_HUMAN (P05177) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450-P3)| (P(3)450) (P450 4) Length = 514 Score = 65.1 bits (157), Expect = 1e-10 Identities = 36/110 (32%), Positives = 55/110 (50%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ P++ K+Q E+ + I + + + D L YL+A I Sbjct: 313 IFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFI 371 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 ET R P +PH D +NG+ IP V VN + DP WE Sbjct: 372 LETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWE 421
>CP2E1_RAT (P05182) Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J)| (P450RLM6) Length = 492 Score = 65.1 bits (157), Expect = 1e-10 Identities = 48/157 (30%), Positives = 74/157 (47%), Gaps = 5/157 (3%) Frame = +1 Query: 58 RRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYN-----LTREQVKAQLV 222 + V+++ LE +S D TD + L+ ++KE + T E V L Sbjct: 236 KNVSEIKQYTLEKAKEHLQSLDINCARDVTDCL--LIEMEKEKHSQEPMYTMENVSVTLA 293 Query: 223 IMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAV 402 +F AGT+T+ + Y + LM+ P++ KL E+ I + + D L+ + Y+ AV Sbjct: 294 DLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRVPAVRDRLD-MPYMDAV 352 Query: 403 IKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVI 513 + E R P +PH A D V GY IP GT VI Sbjct: 353 VHEIQRFINLVPSNLPHEATRDTVFQGYVIPKGTVVI 389
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 65.1 bits (157), Expect = 1e-10 Identities = 46/168 (27%), Positives = 78/168 (46%), Gaps = 4/168 (2%) Frame = +1 Query: 61 RVNKMWDDLLESLIHEHESKPAPALGDDTD---YIHDLLSIQKEYNLTREQVKAQLVIMF 231 R+ KM D+++ ++ P P D + I+ + + ++ ++T VK++ IM Sbjct: 241 RIQKMLDNVVNKKVN-----PLPKTDSDPESNIVINRAMELYRKGDITYMDVKSECCIMI 295 Query: 232 GAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIE-DDLNHLAYLKAVIK 408 AG DTS + + +A+ L +P+ + E+ P H I D+ L YL+ VIK Sbjct: 296 AAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIK 355 Query: 409 ETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 ETLRL P+ + NG IP G + ++ R+P W Sbjct: 356 ETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVW 403
>CP2DR_MESAU (Q9QYG6) Cytochrome P450 2D27 (EC 1.14.14.-) (CYPIID27)| Length = 500 Score = 65.1 bits (157), Expect = 1e-10 Identities = 35/125 (28%), Positives = 65/125 (52%) Frame = +1 Query: 181 EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMV 360 E + E ++ + MF AG T+ + +A+ ++ +PD+ +++Q E+ I + + Sbjct: 290 ESSFNDENLRMVVADMFIAGMVTTSTTLSWALLLMILHPDVQSRVQQEIDDVIGQVRRPE 349 Query: 361 IEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARD 540 + D + Y AVI E R AP+ +PH+ D + G+ IP GT +I N ++ +D Sbjct: 350 MADQAR-MPYTNAVIHEVQRFGDIAPVNIPHMTSHDVEVQGFLIPKGTTLIPNLSSVLKD 408 Query: 541 PSSWE 555 + WE Sbjct: 409 ETVWE 413
>CP2D4_RAT (P13108) Cytochrome P450 2D4 (EC 1.14.14.1) (CYPIID4) (P450-DB4)| (P450-CMF3) (Debrisoquine 4-hydroxylase) Length = 500 Score = 65.1 bits (157), Expect = 1e-10 Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 5/189 (2%) Frame = +1 Query: 4 FPELLKLDIIRWMVCGRARRVNKMWDDLLESLIHEHESKPAPALGDDTDYIHDLLSIQK- 180 FP LL + + V + M D+LL H+ PA D TD L ++K Sbjct: 230 FPMLLHIPGLLGKVFSGKKAFVAMLDELLTE--HKVTWDPAQPPRDLTDAF--LAEVEKA 285 Query: 181 ----EYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKG 348 E + E ++ + +F AG T+ + +A+ ++ +PD+ ++Q E+ I + Sbjct: 286 KGNPESSFNDENLRVVVADLFMAGMVTTSTTLTWALLFMILHPDVQCRVQQEIDEVIGQV 345 Query: 349 KHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRA 528 + + D + + AVI E R PL VPH D + G+ IP GT +I N + Sbjct: 346 RRPEMADQAR-MPFTNAVIHEVQRFADILPLGVPHKTSRDIEVQGFLIPKGTTLITNLSS 404 Query: 529 IARDPSSWE 555 + +D + WE Sbjct: 405 VLKDETVWE 413
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 65.1 bits (157), Expect = 1e-10 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 21/200 (10%) Frame = +1 Query: 19 KLDIIRWMVCGRARR-------VNKMWDDLLESLIHEHESKPAPALGDDTDYIH------ 159 K+ + RW+V R R+ +N D L+ + + L DY++ Sbjct: 269 KIPLARWIV-PRQRKFQDDLKVINTCLDGLIRNAKESRQETDVEKL-QQRDYLNLKDASL 326 Query: 160 -DLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSS 336 L + ++ Q++ L+ M AG +T+ V+ +A+ L QNP M K QAEV Sbjct: 327 LRFLVDMRGADVDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLAQNPSKMKKAQAEVDLV 386 Query: 337 IPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCV-------INGYTIP 495 + G+ + L L Y++ ++ E LRL+ PLL+ +D + +GY IP Sbjct: 387 LGTGRPTF--ESLKELQYIRLIVVEALRLYPQPPLLIRRSLKSDVLPGGHKGEKDGYAIP 444 Query: 496 SGTRVIVNSRAIARDPSSWE 555 +GT V ++ + R P W+ Sbjct: 445 AGTDVFISVYNLHRSPYFWD 464
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 65.1 bits (157), Expect = 1e-10 Identities = 42/126 (33%), Positives = 65/126 (51%) Frame = +1 Query: 175 QKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 Q++ +LT ++ +Q +I AG +TS + + L NP++M KLQ E+ ++ P K Sbjct: 284 QQDKSLTDHEILSQSMIFIFAGYETSSSSLTFLAYNLATNPEVMKKLQEEIDATFP-NKA 342 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 V L + YL VI E+LRL P + +A A ING IP V++ + + Sbjct: 343 PVHYQPLMEMEYLDCVINESLRL-FPIAARLERVAKAAVEINGIVIPKDMVVMIPTWPLH 401 Query: 535 RDPSSW 552 RDP W Sbjct: 402 RDPEIW 407
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 65.1 bits (157), Expect = 1e-10 Identities = 42/126 (33%), Positives = 65/126 (51%) Frame = +1 Query: 175 QKEYNLTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKH 354 Q++ +LT ++ +Q +I AG +TS + + L NP++M KLQ E+ ++ P K Sbjct: 284 QQDKSLTDHEILSQSMIFIFAGYETSSSSLTFLAYNLATNPEVMKKLQEEIDATFP-NKA 342 Query: 355 MVIEDDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIA 534 V L + YL VI E+LRL P + +A A ING IP V++ + + Sbjct: 343 PVHYQPLMEMEYLDCVINESLRL-FPIAARLERVAKAAVEINGVVIPKDMVVMIPTWPLH 401 Query: 535 RDPSSW 552 RDP W Sbjct: 402 RDPEIW 407
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 64.7 bits (156), Expect = 2e-10 Identities = 50/197 (25%), Positives = 95/197 (48%), Gaps = 17/197 (8%) Frame = +1 Query: 13 LLKLDIIRWMVCG--RARRVNKMWDDLLESLIHEHESKPAPALGDDT-----------DY 153 LL +D + ++ R RR ++ D +++I E + P+ G D D+ Sbjct: 240 LLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERR-RTLPSQGVDDFLQAKAKSKTLDF 298 Query: 154 IHDLLSIQKEYN---LTREQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAE 324 I D+L + K+ + L+ E ++A+ G DT+ + + + L ++P+ + + E Sbjct: 299 I-DVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357 Query: 325 VRSSIPKGKHMVIE-DDLNHLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSG 501 V+ + + IE DDL HL +L +KE+LRLH P P++ H+ + +G IP G Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417 Query: 502 TRVIVNSRAIARDPSSW 552 +++ +P+ W Sbjct: 418 IICLISVFGTHHNPAVW 434
>CP1A1_DICLA (P79716) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 520 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/170 (25%), Positives = 80/170 (47%), Gaps = 6/170 (3%) Frame = +1 Query: 64 VNKMWDDLLESLIHEHESK-PAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVI----- 225 +N ++ ++ ++ EH + + D TD + D +K Q+ + ++ Sbjct: 260 INARFNKFVQKIVSEHYTTYDKDNIRDITDSLIDHCEDRKLDENANVQMSDEKIVGIVND 319 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +FGAG DT + +++ L+ P++ +L E++ ++ + ++ D N L +L+A I Sbjct: 320 LFGAGFDTISTALSWSVMYLVAYPEIEERLYQELKENVGLDRTPLLCDRPN-LPFLEAFI 378 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 E R P +PH D +NGY IP T V +N I DP W+ Sbjct: 379 LEIFRHSSFLPFTIPHCTSKDTSLNGYFIPKDTCVFINQWQINHDPELWK 428
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 64.7 bits (156), Expect = 2e-10 Identities = 46/157 (29%), Positives = 71/157 (45%) Frame = +1 Query: 82 DLLESLIHEHESKPAPALGDDTDYIHDLLSIQKEYNLTREQVKAQLVIMFGAGTDTSYIV 261 DLL+ +I+ SK + +L+ E++ AQ +I AG +T+ Sbjct: 270 DLLQLMINSQNSK----------------EMDPHKSLSNEELVAQGIIFIFAGYETTSSA 313 Query: 262 MEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVIKETLRLHMPAPL 441 + L +PD+ KLQ E+ ++ P K D L + YL V+ ETLRL+ P Sbjct: 314 LSLLAYELATHPDVQQKLQEEIEATFP-NKAPPTYDALAQMEYLDMVVNETLRLY-PIAA 371 Query: 442 LVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 + D I+G +P GT V+V + RDP W Sbjct: 372 RLERACKKDVEIHGVFVPKGTVVVVPVFVLHRDPDLW 408
>CP18A_DROME (Q95078) Cytochrome P450 18a1 (EC 1.14.-.-) (CYPXVIIIA1)| Length = 538 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/119 (30%), Positives = 63/119 (52%) Frame = +1 Query: 199 EQVKAQLVIMFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLN 378 EQ+ ++ +F AG +T + + +++NP M ++Q E+ + + + IED L Sbjct: 316 EQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIED-LQ 374 Query: 379 HLAYLKAVIKETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSWE 555 +L ++ I E++R PL H D +NGYTIP+G+ VI ++ DP+ WE Sbjct: 375 YLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWE 433
>CP2J2_HUMAN (P51589) Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic| acid epoxygenase) Length = 502 Score = 64.7 bits (156), Expect = 2e-10 Identities = 35/109 (32%), Positives = 56/109 (51%) Frame = +1 Query: 226 MFGAGTDTSYIVMEYAMARLMQNPDLMTKLQAEVRSSIPKGKHMVIEDDLNHLAYLKAVI 405 +F AGT+T+ + +A+ + P++ K+QAE+ I +G+ + Y AVI Sbjct: 308 LFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR-ESMPYTNAVI 366 Query: 406 KETLRLHMPAPLLVPHLAMADCVINGYTIPSGTRVIVNSRAIARDPSSW 552 E R+ PL VP D + GY +P GT ++ N A+ RDP+ W Sbjct: 367 HEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEW 415 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,444,282 Number of Sequences: 219361 Number of extensions: 2006884 Number of successful extensions: 6638 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5986 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6237 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4585734400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
