ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags25j16 |
|---|---|
| Clone Library Name | barley_pub |
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 70.1 bits (170), Expect = 1e-12 Identities = 32/98 (32%), Positives = 52/98 (53%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L DVLH+R+ + L+W AR ++A+G+A+ L +LH C P ++H++ + SNVLLD Sbjct: 968 SLEDVLHDRKKIGIKLNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDENLE 1027 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQES 298 RV++ G + Y PE +S Sbjct: 1028 ARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQS 1065
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 68.9 bits (167), Expect = 3e-12 Identities = 32/98 (32%), Positives = 51/98 (52%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L DVLH+R+ L+W AR ++A+G+A+ L +LH C P ++H++ + SNVLLD Sbjct: 968 SLEDVLHDRKKTGIKLNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDENLE 1027 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQES 298 RV++ G + Y PE +S Sbjct: 1028 ARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQS 1065
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 68.2 bits (165), Expect = 5e-12 Identities = 33/94 (35%), Positives = 51/94 (54%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D LH+ AL W R+++A G+AK LE+LHD PPV++++F+ SN+LLD F Sbjct: 167 SLEDHLHDLPPDKEALDWNMRMKIAAGAAKGLEFLHDKANPPVIYRDFKSSNILLDEGFH 226 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 ++++ G R+ Y APE Sbjct: 227 PKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCAPE 260
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 67.4 bits (163), Expect = 9e-12 Identities = 31/98 (31%), Positives = 49/98 (50%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L DVLH+ + L+W R ++A+GSA+ L +LH C P ++H++ + SNVLLD Sbjct: 963 SLEDVLHDPKKAGVKLNWSTRRKIAIGSARGLAFLHHNCSPHIIHRDMKSSNVLLDENLE 1022 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQES 298 RV++ G + Y PE +S Sbjct: 1023 ARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQS 1060
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 65.9 bits (159), Expect = 3e-11 Identities = 28/62 (45%), Positives = 43/62 (69%) Frame = +2 Query: 20 LHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 LHER D + L W RL++A G+AK L YLH+ C+P ++H++ + SN+LLD F+ +A+ Sbjct: 819 LHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDENFNSHLAD 878 Query: 200 CG 205 G Sbjct: 879 FG 880
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 65.9 bits (159), Expect = 3e-11 Identities = 30/94 (31%), Positives = 48/94 (51%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +LHD+LHE L W R +A+G+A L YLH C+P +VH++ +P N+LLD+ Sbjct: 897 SLHDILHETNP-PKPLDWSTRHNIAVGTAHGLAYLHFDCDPAIVHRDIKPMNILLDSDLE 955 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 +++ G ++ + Y APE Sbjct: 956 PHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPE 989
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 65.1 bits (157), Expect = 4e-11 Identities = 34/97 (35%), Positives = 52/97 (53%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +LHD+LHE + AL+W R ++ALG A+ L YLH E P++H N NVL+D+ F Sbjct: 454 SLHDLLHESKPRKPALNWARRHKIALGIARGLAYLHTGQEVPIIHGNIRSKNVLVDDFFF 513 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQE 295 R+ E G + ++ Y+APE+ + Sbjct: 514 ARLTEFGLDKIMVQAVADEIVSQAKS-DGYKAPELHK 549
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 65.1 bits (157), Expect = 4e-11 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 2/104 (1%) Frame = +2 Query: 5 TLHDVLHEREDLDSA--LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNR 178 +L VLHE+ L+W AR ++A+G+A+ L +LH +C P ++H++ + SNVLLD Sbjct: 939 SLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDED 998 Query: 179 FSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFT 310 F RV++ G + Y PE +S T Sbjct: 999 FEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCT 1042
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 63.5 bits (153), Expect = 1e-10 Identities = 29/67 (43%), Positives = 43/67 (64%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L DVLH L W RL++AL +A+ L YLH C PP+VH++ + SN+LLD+ + Sbjct: 773 SLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKSSNILLDSDYG 832 Query: 185 VRVAECG 205 +VA+ G Sbjct: 833 AKVADFG 839
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 62.8 bits (151), Expect = 2e-10 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 1/103 (0%) Frame = +2 Query: 5 TLHDVLHEREDLDSA-LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 +L VLHE+ L W AR ++A+G+A+ L +LH +C P ++H++ + SNVLLD F Sbjct: 938 SLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDF 997 Query: 182 SVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFT 310 RV++ G + Y PE +S T Sbjct: 998 VARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCT 1040
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 62.0 bits (149), Expect = 4e-10 Identities = 26/62 (41%), Positives = 42/62 (67%) Frame = +2 Query: 20 LHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 LHE+ D +L W RL++A G+A+ L YLH +CEP ++H++ + SN+LL + F +A+ Sbjct: 828 LHEKVDGPPSLDWKTRLRIARGAAEGLAYLHQSCEPHILHRDIKSSNILLSDTFVAHLAD 887 Query: 200 CG 205 G Sbjct: 888 FG 889
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 61.6 bits (148), Expect = 5e-10 Identities = 26/62 (41%), Positives = 39/62 (62%) Frame = +2 Query: 20 LHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 L ER + L W R ++ALGSA+ L YLHD C+P ++H++ + +N+LLD F V + Sbjct: 375 LRERPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKIIHRDVKAANILLDEEFEAVVGD 434 Query: 200 CG 205 G Sbjct: 435 FG 436
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 61.6 bits (148), Expect = 5e-10 Identities = 26/89 (29%), Positives = 49/89 (55%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 LSW RL+++L +A+ LEYLH+ C+PP+VH++ +P+N+LL+ + ++A+ G Sbjct: 666 LSWEERLKISLDAAQGLEYLHNGCKPPIVHRDVKPTNILLNEKLQAKMADFGLSRSFSVE 725 Query: 230 XXXXXXGRMRALLNYEAPEIQESXTFTDR 316 + + Y PE + ++ Sbjct: 726 GSGQISTVVAGSIGYLDPEYYSTRQMNEK 754
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 58.5 bits (140), Expect = 4e-09 Identities = 31/94 (32%), Positives = 51/94 (54%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L + L R LSW RL+VALG+AK L +LH+ E V++++F+ SN+LLD+ ++ Sbjct: 159 SLENHLFRRGSYFQPLSWTLRLKVALGAAKGLAFLHN-AETSVIYRDFKTSNILLDSEYN 217 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 ++++ G R+ Y APE Sbjct: 218 AKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPE 251
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 57.8 bits (138), Expect = 7e-09 Identities = 30/87 (34%), Positives = 39/87 (44%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 L W R +ALG AK L YLH C V+H + +P N+LLD F ++ + G Sbjct: 627 LDWEGRFNIALGVAKGLAYLHHECLEWVIHCDVKPENILLDQAFEPKITDFGLVKLLNRG 686 Query: 230 XXXXXXGRMRALLNYEAPEIQESXTFT 310 +R L Y APE S T Sbjct: 687 GSTQNVSHVRGTLGYIAPEWVSSLPIT 713
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 57.4 bits (137), Expect = 9e-09 Identities = 28/94 (29%), Positives = 47/94 (50%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D LH L W R+++A G+A+ LEYLHD PPV++++ + SN+LL + Sbjct: 184 SLEDHLHVLPSGKKPLDWNTRMKIAAGAARGLEYLHDRMTPPVIYRDLKCSNILLGEDYQ 243 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 ++++ G R+ Y AP+ Sbjct: 244 PKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPD 277
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 55.8 bits (133), Expect = 3e-08 Identities = 25/68 (36%), Positives = 45/68 (66%), Gaps = 1/68 (1%) Frame = +2 Query: 5 TLHDVLHERE-DLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 +L+ LH ++ +L L+W R+ +A+ +A+ +EYLH PPV+H++ + SN+L+D Sbjct: 587 SLYQHLHGKDPNLKKRLNWARRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEDH 646 Query: 182 SVRVAECG 205 + RVA+ G Sbjct: 647 NARVADFG 654
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 55.8 bits (133), Expect = 3e-08 Identities = 28/94 (29%), Positives = 52/94 (55%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L + L R LSW R+++ALG+A+ L +LH+ +P V++++F+ SN+LLD+ ++ Sbjct: 158 SLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNA-QPQVIYRDFKASNILLDSNYN 216 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 ++++ G R+ Y APE Sbjct: 217 AKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPE 250
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 54.7 bits (130), Expect = 6e-08 Identities = 28/79 (35%), Positives = 46/79 (58%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 LSW RL+VALG+AK L +LH + E V++++F+ SN+LLD+ ++ ++++ G Sbjct: 173 LSWKLRLKVALGAAKGLAFLHSS-ETRVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIG 231 Query: 230 XXXXXXGRMRALLNYEAPE 286 R+ Y APE Sbjct: 232 DKSHVSTRVMGTHGYAAPE 250
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 54.7 bits (130), Expect = 6e-08 Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 2/104 (1%) Frame = +2 Query: 5 TLHDVLH--EREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNR 178 +L +VLH + L W R ++A G+AK L +LH C P ++H++ + SNVLLD Sbjct: 918 SLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDQD 977 Query: 179 FSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFT 310 RV++ G + Y PE +S T Sbjct: 978 MEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCT 1021
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 53.1 bits (126), Expect = 2e-07 Identities = 26/67 (38%), Positives = 41/67 (61%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D LH + S LSW RL + LG+A+A+++LH P ++H + + SNVLLD R Sbjct: 295 SLEDQLHLQTQACSPLSWPQRLDILLGTARAIQFLHQD-SPSLIHGDIKSSNVLLDERLM 353 Query: 185 VRVAECG 205 ++ + G Sbjct: 354 PKLGDFG 360
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 52.0 bits (123), Expect = 4e-07 Identities = 26/79 (32%), Positives = 39/79 (49%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 L W R +VA+ +AK L YLH C P ++H++ + +N+LLD+ F VA+ G Sbjct: 786 LQWETRHRVAVEAAKGLCYLHHDCSPLILHRDVKSNNILLDSDFEAHVADFGLAKFLVDG 845 Query: 230 XXXXXXGRMRALLNYEAPE 286 + Y APE Sbjct: 846 AASECMSSIAGSYGYIAPE 864
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 51.6 bits (122), Expect = 5e-07 Identities = 29/104 (27%), Positives = 47/104 (45%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D L+ L W RL +ALG+A+ L YLH V+H++ + SN+LLD Sbjct: 676 SLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLDQSMC 735 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFTDR 316 +VA+ G +R Y PE ++ +++ Sbjct: 736 AKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEK 779
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 51.2 bits (121), Expect = 6e-07 Identities = 25/67 (37%), Positives = 41/67 (61%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D LH + LSW RL + LG+A+A+++LH P ++H + + SNVLLD R + Sbjct: 295 SLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQD-SPSLIHGDIKSSNVLLDERLT 353 Query: 185 VRVAECG 205 ++ + G Sbjct: 354 PKLGDFG 360
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 51.2 bits (121), Expect = 6e-07 Identities = 29/104 (27%), Positives = 48/104 (46%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D L+ L W RL +ALG+A+ L YLH V+H++ + SN+LLD+ Sbjct: 675 SLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLDHSMC 734 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFTDR 316 +VA+ G +R Y PE ++ +++ Sbjct: 735 AKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEK 778
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 50.8 bits (120), Expect = 8e-07 Identities = 22/62 (35%), Positives = 38/62 (61%) Frame = +2 Query: 20 LHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 L + + L W RL++A+G+A+ L +LH P ++H++ + SN+LLD F +VA+ Sbjct: 1002 LRNQTGMLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVAD 1061 Query: 200 CG 205 G Sbjct: 1062 FG 1063
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 47.8 bits (112), Expect = 7e-06 Identities = 22/66 (33%), Positives = 45/66 (68%) Frame = +2 Query: 8 LHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSV 187 L DVL ++ D +++ +L++ G+A ++YLH + P +VH++ +P+N+L+D F+V Sbjct: 1446 LRDVL---KNPDIKITFANKLKLLYGAAMGIDYLHSS-NPMIVHRDIKPANILVDEHFNV 1501 Query: 188 RVAECG 205 ++A+ G Sbjct: 1502 KIADFG 1507 Score = 40.0 bits (92), Expect = 0.001 Identities = 23/103 (22%), Positives = 54/103 (52%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L+D+L +L + + ++++A ++K + +LH + +VH++ + N+LLD++++ Sbjct: 867 SLYDLLGN--ELIPEIPYALKIKMAYQASKGMHFLHSS---GIVHRDLKSLNLLLDSKWN 921 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFTD 313 V+V++ G + +++ APEI T D Sbjct: 922 VKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVD 964
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 46.6 bits (109), Expect = 2e-05 Identities = 18/61 (29%), Positives = 37/61 (60%) Frame = +2 Query: 23 HEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAEC 202 H+ ++ AL+W R ++LG+A+ + +LH P++H + +P+N+LLD ++ + Sbjct: 306 HKAQNPLPALTWQQRFSISLGTARGIYFLHTARGTPLIHGDIKPANILLDQCLQPKIGDF 365 Query: 203 G 205 G Sbjct: 366 G 366
>RIPK2_MOUSE (P58801) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 539 Score = 46.6 bits (109), Expect = 2e-05 Identities = 21/67 (31%), Positives = 41/67 (61%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L+++LH + + ++W R ++ A + YLH+ PP++H + + N+LLDN F Sbjct: 102 SLNELLHRKTEYPD-IAWPLRFRILHEIALGVNYLHNM-NPPLLHHDLKTQNILLDNEFH 159 Query: 185 VRVAECG 205 V++A+ G Sbjct: 160 VKIADFG 166
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 46.2 bits (108), Expect = 2e-05 Identities = 20/77 (25%), Positives = 42/77 (54%) Frame = +2 Query: 56 WIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXX 235 W R+++ +G+A+ L +LH + + V++++F+ SN+LLD+ + ++++ G Sbjct: 190 WDLRIKIVIGAARGLAFLH-SLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGPADEK 248 Query: 236 XXXXGRMRALLNYEAPE 286 R+ Y APE Sbjct: 249 SHVTTRIMGTYGYAAPE 265
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 45.8 bits (107), Expect = 3e-05 Identities = 22/79 (27%), Positives = 39/79 (49%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 LSW R +VA G+A + +LH+ +H++ + +N+LLD F+ ++++ G Sbjct: 283 LSWHTRCKVAQGTANGIRFLHENHH---IHRDIKSANILLDKDFTAKISDFGLARASARL 339 Query: 230 XXXXXXGRMRALLNYEAPE 286 R+ Y APE Sbjct: 340 AQTVMTSRIVGTTAYMAPE 358
>RIPK2_HUMAN (O43353) Receptor-interacting serine/threonine-protein kinase 2 (EC| 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containi Length = 540 Score = 45.8 bits (107), Expect = 3e-05 Identities = 21/67 (31%), Positives = 41/67 (61%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L+++LH + + ++W R ++ A + YLH+ PP++H + + N+LLDN F Sbjct: 102 SLNELLHRKTEYPD-VAWPLRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFH 159 Query: 185 VRVAECG 205 V++A+ G Sbjct: 160 VKIADFG 166
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 45.4 bits (106), Expect = 4e-05 Identities = 25/70 (35%), Positives = 43/70 (61%), Gaps = 3/70 (4%) Frame = +2 Query: 5 TLHDVLHE---REDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDN 175 +L+ +LH+ RE LD RL +A AK + YLH+ PP+VH++ + N+L+D Sbjct: 632 SLYRLLHKSGAREQLDER----RRLSMAYDVAKGMNYLHNR-NPPIVHRDLKSPNLLVDK 686 Query: 176 RFSVRVAECG 205 +++V+V + G Sbjct: 687 KYTVKVCDFG 696
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 45.1 bits (105), Expect = 5e-05 Identities = 23/83 (27%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Frame = +2 Query: 47 ALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXX 226 +L W +L++ ++ A+ +LH + +PP++H + +P N+LLDN V++++ G Sbjct: 126 SLCWPLKLRIIHETSLAMNFLH-SIKPPLLHLDLKPGNILLDNNMHVKISDFGLSKWMEQ 184 Query: 227 XXXXXXXGR--MRALLNYEAPEI 289 R +R L+Y PE+ Sbjct: 185 STQKQYIERSALRGTLSYIPPEM 207
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 45.1 bits (105), Expect = 5e-05 Identities = 21/79 (26%), Positives = 39/79 (49%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 LSW R ++A G+A + +LH+ +H++ + +N+LLD F+ ++++ G Sbjct: 283 LSWHMRCKIAQGAANGINFLHENHH---IHRDIKSANILLDEAFTAKISDFGLARASEKF 339 Query: 230 XXXXXXGRMRALLNYEAPE 286 R+ Y APE Sbjct: 340 AQTVMTSRIVGTTAYMAPE 358
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 44.7 bits (104), Expect = 6e-05 Identities = 20/52 (38%), Positives = 31/52 (59%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L W RL +AL A+ +EYLH +H++ +PSN+LL + +VA+ G Sbjct: 686 LLWKQRLTLALDVARGVEYLHGLAHQSFIHRDLKPSNILLGDDMRAKVADFG 737
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/83 (26%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Frame = +2 Query: 47 ALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXX 226 +L W R ++ ++ A+ +LH + +PP++H + +P N+LLD+ V++++ G Sbjct: 114 SLCWKLRFRIIHETSLAMNFLH-SIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQ 172 Query: 227 XXXXXXXGR--MRALLNYEAPEI 289 R +R +L+Y PE+ Sbjct: 173 STRMQYIERSALRGMLSYIPPEM 195
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 43.5 bits (101), Expect = 1e-04 Identities = 19/50 (38%), Positives = 32/50 (64%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 LSW R+ V +G AKA++YLH+T V+ N +N+LLD++ ++ + Sbjct: 275 LSWHVRISVLIGIAKAIQYLHNTQPCAVICGNVSSANILLDDQLQPKLTD 324
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor| precursor (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 42.4 bits (98), Expect = 3e-04 Identities = 21/91 (23%), Positives = 40/91 (43%) Frame = +2 Query: 44 SALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXX 223 S L+W R + G A+ L YLH ++H++ + SN+LLD ++++ G Sbjct: 620 SKLNWNERFDITNGVARGLLYLHQDSRFRIIHRDLKVSNILLDKNMIPKISDFGMARIFE 679 Query: 224 XXXXXXXXGRMRALLNYEAPEIQESXTFTDR 316 ++ Y +PE F+++ Sbjct: 680 RDETEANTMKVVGTYGYMSPEYAMYGIFSEK 710
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 39.7 bits (91), Expect = 0.002 Identities = 21/62 (33%), Positives = 30/62 (48%) Frame = +2 Query: 104 YLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAP 283 YLHD P ++H++ +PSNVL D V++A+ G G L Y AP Sbjct: 130 YLHDQ-NPVLLHRDLKPSNVLPDPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAP 188 Query: 284 EI 289 E+ Sbjct: 189 EL 190
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 38.9 bits (89), Expect = 0.003 Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 1/103 (0%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF- 181 +LH+ L+ + + + R AL AKAL YLH + + P+VH++ +P N+LL N+ Sbjct: 90 SLHNYLYGDDKWEYTVEQAVRW--ALQCAKALAYLH-SLDRPIVHRDIKPQNMLLYNQHE 146 Query: 182 SVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFT 310 +++ + G M+ L Y APE + +T Sbjct: 147 DLKICDFGLATDMSNNKTD-----MQGTLRYMAPEAIKHLKYT 184
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 38.9 bits (89), Expect = 0.003 Identities = 16/52 (30%), Positives = 32/52 (61%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L W R ++ +A + +LH PP++H + +P+N+LLD + V++++ G Sbjct: 113 LPWDLRFRIIHETAVGMNFLH-CMAPPLLHLDLKPANILLDAHYHVKISDFG 163
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 38.5 bits (88), Expect = 0.004 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 5/109 (4%) Frame = +2 Query: 5 TLHDVLHERE----DLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLD 172 +LH+ LH + L A+SW A A+ L YLH P++H++ +P N+LL Sbjct: 96 SLHNFLHGKVKPAYSLAHAMSW------ARQCAEGLAYLHAMTPKPLIHRDVKPLNLLLT 149 Query: 173 NR-FSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFTDR 316 N+ ++++ + G R + APE+ E +T++ Sbjct: 150 NKGRNLKICDFGTVADKSTMMT-----NNRGSAAWMAPEVFEGSKYTEK 193
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 38.5 bits (88), Expect = 0.004 Identities = 20/70 (28%), Positives = 34/70 (48%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 +EYLH + H++ +P N+LLD R +++++ G +M L Y Sbjct: 118 VEYLHSI---GITHRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLPYV 174 Query: 278 APEIQESXTF 307 APE+ +S F Sbjct: 175 APELIKSRAF 184
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 38.1 bits (87), Expect = 0.006 Identities = 27/104 (25%), Positives = 49/104 (47%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 +TL D++ E+ AL + + + + AKALE H + ++H++ +P N+L+ Sbjct: 93 KTLKDIIKEK----GALPYEVAISIGIKVAKALECAHKS---GIIHRDVKPQNILVTEEG 145 Query: 182 SVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFTD 313 V+V + G M + +Y +PE Q T+TD Sbjct: 146 VVKVTDFGIAKSMDSSTIAHTNSVMGS-AHYFSPE-QAKGTYTD 187
>FLR4_CAEEL (Q9NLA1) Serine/threonine-protein kinase flr-4 (EC 2.7.11.1)| (Fluoride resistant protein 4) Length = 570 Score = 37.7 bits (86), Expect = 0.007 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 5/82 (6%) Frame = +2 Query: 68 LQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXX 247 ++ + + +AL+YLH+ PPV+H++ + +N+L+ + S+++A G Sbjct: 148 IKYLMETVEALDYLHNL-SPPVIHRDIKAANLLITSNDSIKLANFGLVRDLAVDGFGIAI 206 Query: 248 GR-----MRALLNYEAPEIQES 298 RA L Y APE+ S Sbjct: 207 ASEITLDFRATLLYVAPEVLSS 228
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 37.0 bits (84), Expect = 0.012 Identities = 15/50 (30%), Positives = 30/50 (60%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 L W R+ + +G +KA+ YLH+ V+ + +N+LLD++F ++ + Sbjct: 262 LPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTD 311
>GUC2D_CANFA (O19179) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2)| (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) (Guanylate cyclase E) (GC-E) Length = 1109 Score = 36.6 bits (83), Expect = 0.016 Identities = 21/67 (31%), Positives = 34/67 (50%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +LHD+L +R D L W+ + + L K + YLH V H + N ++D RF Sbjct: 630 SLHDLLAQR---DIKLDWMFKSSLLLDLIKGMRYLH---HRGVAHGRLKSRNCVVDGRFV 683 Query: 185 VRVAECG 205 ++V + G Sbjct: 684 LKVTDHG 690
>AVR2A_SHEEP (Q28560) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 36.6 bits (83), Expect = 0.016 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 12/103 (11%) Frame = +2 Query: 23 HEREDLDSAL-----SWIARLQVALGSAKALEYLH-------DTCEPPVVHQNFEPSNVL 166 HE+ L L SW +A A+ L YLH D +P + H++ + NVL Sbjct: 270 HEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVL 329 Query: 167 LDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQE 295 L N + +A+ G Y APE+ E Sbjct: 330 LKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLE 372
>AVR2A_MOUSE (P27038) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 36.6 bits (83), Expect = 0.016 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 12/103 (11%) Frame = +2 Query: 23 HEREDLDSAL-----SWIARLQVALGSAKALEYLH-------DTCEPPVVHQNFEPSNVL 166 HE+ L L SW +A A+ L YLH D +P + H++ + NVL Sbjct: 270 HEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVL 329 Query: 167 LDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQE 295 L N + +A+ G Y APE+ E Sbjct: 330 LKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLE 372
>AVR2A_HUMAN (P27037) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) (ACTRIIA) Length = 513 Score = 36.6 bits (83), Expect = 0.016 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 12/103 (11%) Frame = +2 Query: 23 HEREDLDSAL-----SWIARLQVALGSAKALEYLH-------DTCEPPVVHQNFEPSNVL 166 HE+ L L SW +A A+ L YLH D +P + H++ + NVL Sbjct: 270 HEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVL 329 Query: 167 LDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQE 295 L N + +A+ G Y APE+ E Sbjct: 330 LKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLE 372
>AVR2A_BOVIN (Q28043) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 36.6 bits (83), Expect = 0.016 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 12/103 (11%) Frame = +2 Query: 23 HEREDLDSAL-----SWIARLQVALGSAKALEYLH-------DTCEPPVVHQNFEPSNVL 166 HE+ L L SW +A A+ L YLH D +P + H++ + NVL Sbjct: 270 HEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVL 329 Query: 167 LDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQE 295 L N + +A+ G Y APE+ E Sbjct: 330 LKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLE 372
>RIPK5_XENLA (Q67E01) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 916 Score = 36.6 bits (83), Expect = 0.016 Identities = 19/56 (33%), Positives = 32/56 (57%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + LS RLQ+AL + + +LH+ VVH++ + NVLLD + ++ + G Sbjct: 734 LKTGLSLETRLQIALDVVEGIRFLHNQ---GVVHRDIKLKNVLLDKKHRAKITDLG 786
>GUC2E_RAT (P51840) Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate| cyclase 2E) Length = 1108 Score = 36.6 bits (83), Expect = 0.016 Identities = 21/67 (31%), Positives = 34/67 (50%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +LHD+L +R D L W+ + + L K + YLH V H + N ++D RF Sbjct: 629 SLHDLLAQR---DIKLDWMFKSSLLLDLIKGMRYLH---HRGVAHGRLKSRNCVVDGRFV 682 Query: 185 VRVAECG 205 ++V + G Sbjct: 683 LKVTDHG 689
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 36.6 bits (83), Expect = 0.016 Identities = 21/65 (32%), Positives = 34/65 (52%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNY 274 A+EY H VVH++ +P N+LLD++++V++A+ G LNY Sbjct: 127 AVEYCHRN---KVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGHFLKTS---CGSLNY 180 Query: 275 EAPEI 289 APE+ Sbjct: 181 AAPEV 185
>IRAK2_HUMAN (O43187) Interleukin-1 receptor-associated kinase-like 2 (IRAK-2)| Length = 590 Score = 36.2 bits (82), Expect = 0.021 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVA 196 L W R+ + G A+EYLH ++H N + SNVLLD + ++A Sbjct: 307 LPWPQRVSICSGLLCAVEYLHGL---EIIHSNVKSSNVLLDQNLTPKLA 352
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 36.2 bits (82), Expect = 0.021 Identities = 21/67 (31%), Positives = 39/67 (58%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L +LHE++ + L ++L +A+ AK +EYLH+ + P++H++ N+LL Sbjct: 647 SLFSLLHEQKRI---LDLQSKLIIAVDVAKGMEYLHNLTQ-PIIHRDLNSHNILLYEDGH 702 Query: 185 VRVAECG 205 VA+ G Sbjct: 703 AVVADFG 709
>GAK_MOUSE (Q99KY4) Cyclin G-associated kinase (EC 2.7.11.1)| Length = 1305 Score = 36.2 bits (82), Expect = 0.021 Identities = 17/84 (20%), Positives = 44/84 (52%) Frame = +2 Query: 26 EREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +R + LS + L++ + +A++++H +PP++H++ + N+LL N+ ++++ + G Sbjct: 135 KRVECKGPLSCDSILKIFYQTCRAVQHMHRQ-KPPIIHRDLKVENLLLSNQGTIKLCDFG 193 Query: 206 XXXXXXXXXXXXXXGRMRALLNYE 277 + RA++ E Sbjct: 194 SATTISHYPDYSWSAQKRAMVEEE 217
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.12.2)| Length = 363 Score = 36.2 bits (82), Expect = 0.021 Identities = 21/80 (26%), Positives = 36/80 (45%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXG 250 ++A G L YLHD ++H++ +PSN+LL ++ V++ + G G Sbjct: 185 KIAFGVLSGLSYLHDR---KIIHRDIKPSNILLTSKGQVKLCDFGVSGELVNSLAGTFTG 241 Query: 251 RMRALLNYEAPEIQESXTFT 310 Y APE ++T Sbjct: 242 TS----YYMAPERISGGSYT 257
>AVR2A_RAT (P38444) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type IIA) (ACTR-IIA) Length = 513 Score = 36.2 bits (82), Expect = 0.021 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 12/103 (11%) Frame = +2 Query: 23 HEREDLDSAL-----SWIARLQVALGSAKALEYLH-------DTCEPPVVHQNFEPSNVL 166 HE+ L L SW +A A+ L YLH D +P + H++ + NVL Sbjct: 270 HEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVL 329 Query: 167 LDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQE 295 L N + +A+ G Y APE+ E Sbjct: 330 LKNNLTACIADFGLALKFEAGKSGGDTHGQVGTRRYMAPEVLE 372
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 35.8 bits (81), Expect = 0.028 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 2/106 (1%) Frame = +2 Query: 5 TLHDVLHEREDLD--SALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNR 178 TL DVL ER L +AL + + ALG+A + VH++ +P NVL+ + Sbjct: 102 TLRDVLRERGALQPRAALDILEPVLAALGAAHRAGF---------VHRDMKPENVLIGDD 152 Query: 179 FSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFTDR 316 V+VA+ G G + ++Y APE E T R Sbjct: 153 GRVKVADFG--LVRAVDSVTNTTGTVLGTVSYLAPEQIEHGTADPR 196
>TOPK_MOUSE (Q9JJ78) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) Length = 330 Score = 35.8 bits (81), Expect = 0.028 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 2/70 (2%) Frame = +2 Query: 2 RTLHDVLHER-EDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNR 178 ++L+D++ ER +D S L+VAL A+ L+YLH E ++H + + SNV++ Sbjct: 120 KSLNDLIEERNKDSGSPFPAAVILRVALHMARGLKYLHQ--EKKLLHGDIKSSNVVIKGD 177 Query: 179 F-SVRVAECG 205 F ++++ + G Sbjct: 178 FETIKICDVG 187
>GAK_RAT (P97874) Cyclin G-associated kinase (EC 2.7.11.1)| Length = 1305 Score = 35.8 bits (81), Expect = 0.028 Identities = 17/83 (20%), Positives = 43/83 (51%) Frame = +2 Query: 29 REDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGX 208 R + LS + L++ + +A++++H +PP++H++ + N+LL N+ ++++ + G Sbjct: 136 RVECKGPLSCDSILKIFYQTCRAVQHMHRQ-KPPIIHRDLKVENLLLSNQGTIKLCDFGS 194 Query: 209 XXXXXXXXXXXXXGRMRALLNYE 277 + RA++ E Sbjct: 195 ATTISHYPDYSWSAQKRAMVEEE 217
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 35.8 bits (81), Expect = 0.028 Identities = 21/67 (31%), Positives = 38/67 (56%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L +LHE++ + L ++L +A+ AK +EYLH + P++H++ N+LL Sbjct: 545 SLFSLLHEQKRI---LDLQSKLIIAVDVAKGMEYLHSLTQ-PIIHRDLNSHNILLYEDGH 600 Query: 185 VRVAECG 205 VA+ G Sbjct: 601 AVVADFG 607
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 35.8 bits (81), Expect = 0.028 Identities = 21/67 (31%), Positives = 38/67 (56%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L +LHE++ + L ++L +A+ AK +EYLH + P++H++ N+LL Sbjct: 544 SLFSLLHEQKRI---LDLQSKLIIAVDVAKGMEYLHSLTQ-PIIHRDLNSHNILLYEDGH 599 Query: 185 VRVAECG 205 VA+ G Sbjct: 600 AVVADFG 606
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 35.8 bits (81), Expect = 0.028 Identities = 23/76 (30%), Positives = 36/76 (47%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALL 268 A AL Y HD V+H++ +P N+LL R V++A+ G G L Sbjct: 151 ADALTYCHDK---KVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCG----TL 203 Query: 269 NYEAPEIQESXTFTDR 316 +Y PE+ E T+ ++ Sbjct: 204 DYLPPEMIEGRTYDEK 219
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 35.4 bits (80), Expect = 0.036 Identities = 18/65 (27%), Positives = 32/65 (49%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLN 271 +AL Y+H +VH++ +PSN+++D+ VR+ + G G++ Sbjct: 230 EALAYIHGH---GLVHRDLKPSNIMVDDDRQVRLMDFGLAKFLADDAAITEAGKLVGTYR 286 Query: 272 YEAPE 286 Y APE Sbjct: 287 YMAPE 291
>GAK_HUMAN (O14976) Cyclin G-associated kinase (EC 2.7.11.1)| Length = 1311 Score = 35.4 bits (80), Expect = 0.036 Identities = 15/70 (21%), Positives = 38/70 (54%) Frame = +2 Query: 68 LQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXX 247 L++ + +A++++H +PP++H++ + N+LL N+ ++++ + G Sbjct: 149 LKIFYQTCRAVQHMHRQ-KPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWS 207 Query: 248 GRMRALLNYE 277 + RAL+ E Sbjct: 208 AQRRALVEEE 217
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 35.4 bits (80), Expect = 0.036 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = +2 Query: 65 RLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDN 175 RL++AL AK + YLH PP++H++ N+LLD+ Sbjct: 1392 RLKLALDIAKGMNYLHGWT-PPILHRDLSSRNILLDH 1427
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 35.4 bits (80), Expect = 0.036 Identities = 14/34 (41%), Positives = 25/34 (73%) Frame = +2 Query: 104 YLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 YLH + +PP++H++ +PSN+LLD ++A+ G Sbjct: 131 YLH-SLDPPLLHRDLKPSNILLDPELHAKLADFG 163
>BYR2_SCHPO (P28829) Protein kinase byr2 (EC 2.7.11.25) (Protein kinase ste8)| (MAPK kinase kinase) (MAPKKK) Length = 659 Score = 35.4 bits (80), Expect = 0.036 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLN 271 K LEYLH +VH++ + +N+L+DN+ +++++ G G R Sbjct: 508 KGLEYLHSR---GIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQ 564 Query: 272 ----YEAPEIQESXTFTDR 316 + APE+ + T++ Sbjct: 565 GSSFWMAPEVVKQTMHTEK 583
>RIPK5_XENTR (Q67E00) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 918 Score = 35.4 bits (80), Expect = 0.036 Identities = 18/56 (32%), Positives = 32/56 (57%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + LS RLQ+AL + + +LH+ +VH++ + NVLLD + ++ + G Sbjct: 736 LKTGLSLETRLQIALDVVEGIRFLHNQ---GLVHRDIKLKNVLLDKKHRAKITDLG 788
>HEP_DROME (Q23977) Dual specificity mitogen-activated protein kinase kinase| hemipterous (EC 2.7.12.2) (MAPKK) Length = 1178 Score = 35.0 bits (79), Expect = 0.047 Identities = 15/45 (33%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V + + AL YL D + V+H++ +PSN+L+D R ++++ + G Sbjct: 298 KVTVATVNALSYLKD--KHGVIHRDVKPSNILIDERGNIKLCDFG 340
>AVR2A_XENLA (P27039) Activin receptor type 2A precursor (EC 2.7.11.30) (Activin| receptor type II) (ACTR-II) Length = 514 Score = 35.0 bits (79), Expect = 0.047 Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 7/91 (7%) Frame = +2 Query: 44 SALSWIARLQVALGSAKALEYLH-------DTCEPPVVHQNFEPSNVLLDNRFSVRVAEC 202 + +SW +A A+ L +LH D +P V H++ + NVLL N + +A+ Sbjct: 283 NVVSWNELCLIAETMARGLSHLHEDIPGLKDGHKPAVAHRDIKSKNVLLKNNLTACIADF 342 Query: 203 GXXXXXXXXXXXXXXGRMRALLNYEAPEIQE 295 G Y APE+ E Sbjct: 343 GLALKFEAGKSAGDTHGQVGTRRYMAPEVLE 373
>PKNX_STRCO (Q9XA16) Probable serine/threonine-protein kinase SCO3848 (EC| 2.7.11.1) Length = 673 Score = 34.7 bits (78), Expect = 0.062 Identities = 21/67 (31%), Positives = 36/67 (53%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL ++LH L + L++ +G +ALEY H +VH++ +P+NV+L Sbjct: 99 TLRELLHSGRKLLPERT----LEMTIGILQALEYSH---RAGIVHRDIKPANVMLTRNGQ 151 Query: 185 VRVAECG 205 V+V + G Sbjct: 152 VKVMDFG 158
>M3K3_ARATH (O22042) Mitogen-activated protein kinase kinase kinase 3 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 3) Length = 651 Score = 34.7 bits (78), Expect = 0.062 Identities = 17/64 (26%), Positives = 33/64 (51%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LEYLH+ ++H++ + +N+L+DN+ +R+A+ G M+ + Sbjct: 184 LEYLHNN---GIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWM 240 Query: 278 APEI 289 APE+ Sbjct: 241 APEV 244
>GUC2F_HUMAN (P51841) Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2)| (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F) Length = 1108 Score = 34.7 bits (78), Expect = 0.062 Identities = 25/95 (26%), Positives = 41/95 (43%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D+L + D L W+ + + L K ++YLH VH + N ++D RF Sbjct: 630 SLEDILTNQ---DVKLDWMFKSSLLLDLIKGMKYLH---HREFVHGRLKSRNCVVDGRFV 683 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEI 289 ++V + G M LL + APE+ Sbjct: 684 LKVTDYGFNDILEMLRLSEEESSMEELL-WTAPEL 717
>RIPK5_CHICK (Q6XUX0) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 34.3 bits (77), Expect = 0.081 Identities = 18/56 (32%), Positives = 30/56 (53%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + L RLQ+AL + + YLH +VH++ + NVLLD + ++ + G Sbjct: 746 LKAGLELETRLQIALDVVEGIRYLHSQ---GLVHRDIKLKNVLLDKKNRAKITDLG 798
>M3K1_ARATH (O22040) Mitogen-activated protein kinase kinase kinase 1 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 1) Length = 666 Score = 34.3 bits (77), Expect = 0.081 Identities = 16/64 (25%), Positives = 33/64 (51%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LEYLH+ ++H++ + +N+L+DN+ +++A+ G M+ + Sbjct: 185 LEYLHNHA---IMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWM 241 Query: 278 APEI 289 APE+ Sbjct: 242 APEV 245
>MP2K6_MOUSE (P70236) Dual specificity mitogen-activated protein kinase kinase 6| (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3) Length = 334 Score = 34.3 bits (77), Expect = 0.081 Identities = 16/45 (35%), Positives = 29/45 (64%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A+ KALE+LH V+H++ +PSNVL++ V++ + G Sbjct: 157 KIAVSIVKALEHLHSKLS--VIHRDVKPSNVLINTLGQVKMCDFG 199
>MP2K3_XENLA (P39746) Dual specificity mitogen-activated protein kinase kinase 3| (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK-ERK kinase 3) (Fragment) Length = 62 Score = 34.3 bits (77), Expect = 0.081 Identities = 16/45 (35%), Positives = 28/45 (62%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A+ KALE+LH V+H++ +PSNVL++ V + + G Sbjct: 2 KIAVSIVKALEHLHSKLS--VIHRDVKPSNVLINKEGQVNMCDFG 44
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 34.3 bits (77), Expect = 0.081 Identities = 18/68 (26%), Positives = 32/68 (47%) Frame = +2 Query: 104 YLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAP 283 YLH + H++ +P N+LLD R ++++++ G +M L Y AP Sbjct: 120 YLHGI---GITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAP 176 Query: 284 EIQESXTF 307 E+ + F Sbjct: 177 ELLKRKEF 184
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 34.3 bits (77), Expect = 0.081 Identities = 18/68 (26%), Positives = 32/68 (47%) Frame = +2 Query: 104 YLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAP 283 YLH + H++ +P N+LLD R ++++++ G +M L Y AP Sbjct: 120 YLHGI---GITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAP 176 Query: 284 EIQESXTF 307 E+ + F Sbjct: 177 ELLKRKEF 184
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 34.3 bits (77), Expect = 0.081 Identities = 18/68 (26%), Positives = 32/68 (47%) Frame = +2 Query: 104 YLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAP 283 YLH + H++ +P N+LLD R ++++++ G +M L Y AP Sbjct: 120 YLHGI---GITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAP 176 Query: 284 EIQESXTF 307 E+ + F Sbjct: 177 ELLKRREF 184
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 34.3 bits (77), Expect = 0.081 Identities = 18/59 (30%), Positives = 34/59 (57%) Frame = +2 Query: 29 REDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + +D LS R+ V + + + YLHD V+H++ +P N+L+D F +++A+ G Sbjct: 105 KTQIDVPLSLKGRIIVE--AIEGMCYLHDK---GVIHKDLKPENILVDRDFHIKIADLG 158
>MP2K2_XENLA (Q07192) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (MAPK-ERK kinase 2) (Fragment) Length = 446 Score = 34.3 bits (77), Expect = 0.081 Identities = 13/45 (28%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++ L + KAL +L + + ++H++ +PSN+LLD ++++ + G Sbjct: 254 KITLATVKALNHLKENLK--IIHRDIKPSNILLDTNGNIKLCDFG 296
>RIPK5_RAT (Q6XUX2) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 927 Score = 33.9 bits (76), Expect = 0.11 Identities = 18/56 (32%), Positives = 31/56 (55%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + LS RLQ+AL + + +LH +VH++ + NVLLD + ++ + G Sbjct: 743 LKAGLSLETRLQIALDVVEGIRFLH---SQGLVHRDIKLKNVLLDKQNRAKITDLG 795
>MP2K3_MOUSE (O09110) Dual specificity mitogen-activated protein kinase kinase 3| (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) Length = 347 Score = 33.9 bits (76), Expect = 0.11 Identities = 15/45 (33%), Positives = 29/45 (64%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A+ +ALE+LH V+H++ +PSNVL++ V++ + G Sbjct: 168 EIAVSIVRALEHLHSKLS--VIHRDVKPSNVLINKEGHVKMCDFG 210
>MP2K3_HUMAN (P46734) Dual specificity mitogen-activated protein kinase kinase 3| (EC 2.7.12.2) (MAP kinase kinase 3) (MAPKK 3) (MAPK/ERK kinase 3) Length = 347 Score = 33.9 bits (76), Expect = 0.11 Identities = 15/45 (33%), Positives = 29/45 (64%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A+ +ALE+LH V+H++ +PSNVL++ V++ + G Sbjct: 168 EIAVSIVRALEHLHSKLS--VIHRDVKPSNVLINKEGHVKMCDFG 210
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 33.9 bits (76), Expect = 0.11 Identities = 17/62 (27%), Positives = 30/62 (48%) Frame = +2 Query: 104 YLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAP 283 YLH + H++ +P N+LLD R ++++++ G +M L Y AP Sbjct: 120 YLHSM---GITHRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAP 176 Query: 284 EI 289 E+ Sbjct: 177 EL 178
>MP2K4_HUMAN (P45985) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-Jun N-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1) Length = 399 Score = 33.9 bits (76), Expect = 0.11 Identities = 13/45 (28%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++ L + KAL +L + + ++H++ +PSN+LLD ++++ + G Sbjct: 207 KITLATVKALNHLKENLK--IIHRDIKPSNILLDRSGNIKLCDFG 249
>M3K2_ARATH (Q9FZ36) Mitogen-activated protein kinase kinase kinase 2 (EC| 2.7.11.25) (Arabidospsis NPK1-related protein kinase 2) Length = 651 Score = 33.9 bits (76), Expect = 0.11 Identities = 16/64 (25%), Positives = 33/64 (51%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LEYLH+ ++H++ + +N+L+DN+ +++A+ G M+ + Sbjct: 184 LEYLHNHA---IMHRDIKGANILVDNQGCIKLADFGASKQVAELATISGAKSMKGTPYWM 240 Query: 278 APEI 289 APE+ Sbjct: 241 APEV 244
>GUC2F_RAT (P51842) Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2)| (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F) Length = 1108 Score = 33.9 bits (76), Expect = 0.11 Identities = 19/68 (27%), Positives = 34/68 (50%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 R+L D+L + D L W+ + + L K ++YLH +H + N ++D RF Sbjct: 629 RSLEDILTQD---DVKLDWMFKSSLLLDLIKGMKYLH---HREFIHGRLKSRNCVVDGRF 682 Query: 182 SVRVAECG 205 ++V + G Sbjct: 683 VLKVTDYG 690
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 33.9 bits (76), Expect = 0.11 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Frame = +2 Query: 104 YLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRA--LLNYE 277 YLH + P ++H++ +PSNVLLD ++A+ G G + L Y Sbjct: 131 YLH-SLNPSLLHRDLKPSNVLLDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYL 189 Query: 278 APEIQES 298 APE+ ++ Sbjct: 190 APELLDN 196
>MP2K4_MOUSE (P47809) Dual specificity mitogen-activated protein kinase kinase 4| (EC 2.7.12.2) (MAP kinase kinase 4) (MAPKK 4) (MAPK/ERK kinase 4) (JNK-activating kinase 1) (C-JUN N-terminal kinase kinase 1) (JNK kinase 1) (JNKK 1) (SAPK/ERK kinase 1) (SE Length = 397 Score = 33.9 bits (76), Expect = 0.11 Identities = 13/45 (28%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++ L + KAL +L + + ++H++ +PSN+LLD ++++ + G Sbjct: 205 KITLATVKALNHLKENLK--IIHRDIKPSNILLDRSGNIKLCDFG 247
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 33.9 bits (76), Expect = 0.11 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H C +V+++ +P+N+LLD +R+++ G G Y Sbjct: 306 LEHMHKRC---IVYRDLKPANILLDENGHIRISDLGLACDFSKKKPHASVGTH----GYM 358 Query: 278 APEIQESXTFTD 313 APE+ T D Sbjct: 359 APEVLSKGTSYD 370
>GUC2G_MOUSE (Q6TL19) Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl| cyclase receptor G) (mGC-G) Length = 1100 Score = 33.9 bits (76), Expect = 0.11 Identities = 20/67 (29%), Positives = 33/67 (49%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L DV+ D + WI +L A L +LH + P H N +PSN L+D+ Sbjct: 639 SLQDVMRNS---DHEIDWIFKLSFAYDIVNGLLFLHGS--PLRSHGNLKPSNCLVDSHMQ 693 Query: 185 VRVAECG 205 ++++ G Sbjct: 694 LKLSGFG 700
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 33.5 bits (75), Expect = 0.14 Identities = 14/37 (37%), Positives = 25/37 (67%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A+EY H +VH++ +P N+LLD+ +V++A+ G Sbjct: 143 AIEYCH---RHKIVHRDLKPENLLLDDNLNVKIADFG 176
>GUC2D_BOVIN (P55203) Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2)| (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC) (Guanylate cyclase E) (GC-E) Length = 1110 Score = 33.5 bits (75), Expect = 0.14 Identities = 20/67 (29%), Positives = 33/67 (49%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D+L +R D L W+ + + L K + YLH V H + N ++D RF Sbjct: 631 SLQDLLAQR---DIKLDWMFKSSLLLDLIKGIRYLH---HRGVAHGRLKSRNCVVDGRFV 684 Query: 185 VRVAECG 205 ++V + G Sbjct: 685 LKVTDHG 691
>MP2K6_HUMAN (P52564) Dual specificity mitogen-activated protein kinase kinase 6| (EC 2.7.12.2) (MAP kinase kinase 6) (MAPKK 6) (MAPK/ERK kinase 6) (SAPKK3) Length = 334 Score = 33.5 bits (75), Expect = 0.14 Identities = 16/45 (35%), Positives = 29/45 (64%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A+ KALE+LH V+H++ +PSNVL++ V++ + G Sbjct: 157 KIAVSIVKALEHLHSKLS--VIHRDVKPSNVLINALGQVKMCDFG 199
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 33.5 bits (75), Expect = 0.14 Identities = 19/70 (27%), Positives = 38/70 (54%), Gaps = 3/70 (4%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVAL---GSAKALEYLHDTCEPPVVHQNFEPSNVLLDN 175 +L D++ D++ S + Q+A + + L++LHD ++H++ + NVLLD Sbjct: 647 SLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDK---HIIHRDIKSDNVLLDT 703 Query: 176 RFSVRVAECG 205 R V++ + G Sbjct: 704 RARVKITDFG 713
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 33.5 bits (75), Expect = 0.14 Identities = 14/37 (37%), Positives = 26/37 (70%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A+EY H +VH++ +P N+LLD++ +V++A+ G Sbjct: 162 AVEYCH---RHKIVHRDLKPENLLLDDQLNVKIADFG 195
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 33.5 bits (75), Expect = 0.14 Identities = 14/45 (31%), Positives = 28/45 (62%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++ L + + YLH V+H++ +P N+L+DN F +++A+ G Sbjct: 117 RIILEIIEGMCYLHGK---GVIHKDLKPENILVDNDFHIKIADLG 158
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 33.5 bits (75), Expect = 0.14 Identities = 14/37 (37%), Positives = 26/37 (70%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A+EY H +VH++ +P N+LLD++ +V++A+ G Sbjct: 161 AVEYCH---RHKIVHRDLKPENLLLDDQLNVKIADFG 194
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 33.1 bits (74), Expect = 0.18 Identities = 19/67 (28%), Positives = 33/67 (49%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL +R D A ++A + +A+ S L Y VH++ +P N+L+D Sbjct: 164 TLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHY---------VHRDIKPDNILMDMNGH 214 Query: 185 VRVAECG 205 +R+A+ G Sbjct: 215 IRLADFG 221
>GUC2F_BOVIN (O02740) Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2)| (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F) Length = 1103 Score = 33.1 bits (74), Expect = 0.18 Identities = 19/68 (27%), Positives = 33/68 (48%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 R+L D+L + D L W+ + + L K ++YLH H + N ++D RF Sbjct: 629 RSLEDILMNQ---DVKLDWMFKSSLLLDLIKGMKYLH---HREFAHGRLKSRNCVVDGRF 682 Query: 182 SVRVAECG 205 ++V + G Sbjct: 683 VLKVTDYG 690
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 33.1 bits (74), Expect = 0.18 Identities = 20/68 (29%), Positives = 37/68 (54%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 +TL D++ ++ ALS QV LG AL+Y H ++H++ +P N+++ + Sbjct: 106 QTLRDIIK----VNGALSQRDCEQVMLGVLNALDYSH---RMGIIHRDIKPGNIMISEQG 158 Query: 182 SVRVAECG 205 V+V + G Sbjct: 159 VVKVMDFG 166
>MP2K7_HUMAN (O14733) Dual specificity mitogen-activated protein kinase kinase 7| (EC 2.7.12.2) (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) Length = 419 Score = 33.1 bits (74), Expect = 0.18 Identities = 17/49 (34%), Positives = 32/49 (65%) Frame = +2 Query: 59 IARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + ++ VA+ KAL YL + + V+H++ +PSN+LLD R +++ + G Sbjct: 219 LGKMTVAI--VKALYYLKE--KHGVIHRDVKPSNILLDERGQIKLCDFG 263
>GUC2G_RAT (P55205) Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl| cyclase receptor G) (GC-G) (Kinase-like domain-containing soluble guanylyl cyclase) (ksGC) Length = 1100 Score = 33.1 bits (74), Expect = 0.18 Identities = 20/67 (29%), Positives = 32/67 (47%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L DVL D + WI +L + +LH + P H N +PSN L+D+ Sbjct: 639 SLKDVLRNS---DHEMDWIFKLSFVYDIVNGMLFLHGS--PLRSHGNLKPSNCLVDSHMQ 693 Query: 185 VRVAECG 205 +++A G Sbjct: 694 LKLAGFG 700
>RIPK5_PANTR (Q4VSN5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 32.7 bits (73), Expect = 0.24 Identities = 17/56 (30%), Positives = 31/56 (55%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + L+ RLQ+AL + + +LH +VH++ + NVLLD + ++ + G Sbjct: 746 LKAGLTLETRLQIALDVVEGIRFLHSQ---GLVHRDIKLKNVLLDKQNRAKITDLG 798
>RIPK5_CANFA (Q4VSN4) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 931 Score = 32.7 bits (73), Expect = 0.24 Identities = 17/56 (30%), Positives = 31/56 (55%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + L+ RLQ+AL + + +LH +VH++ + NVLLD + ++ + G Sbjct: 747 LKAGLTLETRLQIALDVVEGIRFLHSQ---GLVHRDIKLKNVLLDKQNRAKITDLG 799
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 32.7 bits (73), Expect = 0.24 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A+EY H +VH++ +P N+LLD +V++A+ G Sbjct: 164 AVEYCH---RHKIVHRDLKPENLLLDEHLNVKIADFG 197
>RIPK5_MOUSE (Q6XUX1) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 927 Score = 32.7 bits (73), Expect = 0.24 Identities = 17/56 (30%), Positives = 31/56 (55%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + L+ RLQ+AL + + +LH +VH++ + NVLLD + ++ + G Sbjct: 743 LKAGLTLETRLQIALDVVEGIRFLHSQ---GLVHRDIKLKNVLLDKQNRAKITDLG 795
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 32.7 bits (73), Expect = 0.24 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A+EY H +VH++ +P N+LLD +V++A+ G Sbjct: 148 AVEYCH---RHKIVHRDLKPENLLLDEHLNVKIADFG 181
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 32.7 bits (73), Expect = 0.24 Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 3/77 (3%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGR-MRALLN 271 A+ YLH C V H++ +P N+LLD ++++A+ G R Sbjct: 128 AINYLHVECG--VAHRDIKPENILLDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPP 185 Query: 272 YEAPEI--QESXTFTDR 316 Y APE+ E + DR Sbjct: 186 YMAPEVLYSEEGYYADR 202
>GCN2_ARATH (Q9LX30) Probable serine/threonine-protein kinase GCN2 (EC| 2.7.11.1) Length = 1241 Score = 32.7 bits (73), Expect = 0.24 Identities = 17/68 (25%), Positives = 31/68 (45%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 RTL V D +W Q+ G L ++H ++H++F P+N+ D R Sbjct: 546 RTLRQVFESYNHFDKDFAWHLIRQIVEG----LAHIHGQ---GIIHRDFTPNNIFFDARN 598 Query: 182 SVRVAECG 205 +++ + G Sbjct: 599 DIKIGDFG 606
>GCN2_YEAST (P15442) Serine/threonine-protein kinase GCN2 (EC 2.7.11.1)| Length = 1590 Score = 32.7 bits (73), Expect = 0.24 Identities = 19/68 (27%), Positives = 38/68 (55%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 RTL+D++H E+L+ RL + +AL Y+H ++H++ +P N+ +D Sbjct: 725 RTLYDLIHS-ENLNQQRDEYWRLFRQI--LEALSYIHSQ---GIIHRDLKPMNIFIDESR 778 Query: 182 SVRVAECG 205 +V++ + G Sbjct: 779 NVKIGDFG 786
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 32.7 bits (73), Expect = 0.24 Identities = 14/36 (38%), Positives = 25/36 (69%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +EY H VVH++ +P N+LLD+R ++++A+ G Sbjct: 131 VEYCHRNM---VVHRDLKPENLLLDSRCNIKIADFG 163
>RN5A_HUMAN (Q05823) 2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent| RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4) Length = 741 Score = 32.7 bits (73), Expect = 0.24 Identities = 18/60 (30%), Positives = 34/60 (56%) Frame = +2 Query: 20 LHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 +H ED+++ AR V KA++ LH +C HQ+ +P N+L+D++ + +A+ Sbjct: 447 VHRGEDVENEEDEFAR-NVLSSIFKAVQELHLSCG--YTHQDLQPQNILIDSKKAAHLAD 503
>RIPK5_FUGRU (Q4VSN2) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 921 Score = 32.7 bits (73), Expect = 0.24 Identities = 17/56 (30%), Positives = 32/56 (57%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + LS RLQ+AL + + +LH+ ++H++ + NVLLD + ++ + G Sbjct: 738 LKAGLSLQERLQIALDVVEGIRFLHN---QGLLHRDIKLKNVLLDKQNRAKITDLG 790
>RIPK5_HUMAN (Q6XUX3) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) Length = 929 Score = 32.7 bits (73), Expect = 0.24 Identities = 17/56 (30%), Positives = 31/56 (55%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + L+ RLQ+AL + + +LH +VH++ + NVLLD + ++ + G Sbjct: 745 LKAGLTLETRLQIALDVVEGIRFLHSQ---GLVHRDIKLKNVLLDKQNRAKITDLG 797
>RK_HUMAN (Q15835) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 563 Score = 32.3 bits (72), Expect = 0.31 Identities = 15/36 (41%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LE+LH + +V+++ +P NVLLDN +VR+++ G Sbjct: 305 LEHLH---QRRIVYRDLKPENVLLDNDGNVRISDLG 337
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 32.3 bits (72), Expect = 0.31 Identities = 19/67 (28%), Positives = 37/67 (55%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D+L E E ++ L W+ R + K + +LH++ H N + SN ++D+RF Sbjct: 607 SLQDIL-ENESIN--LDWMFRYSLINDIVKGMNFLHNSYIGS--HGNLKSSNCVVDSRFV 661 Query: 185 VRVAECG 205 +++ + G Sbjct: 662 LKITDYG 668
>RIPK5_BOVIN (Q4TVR5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 928 Score = 32.3 bits (72), Expect = 0.31 Identities = 17/56 (30%), Positives = 31/56 (55%) Frame = +2 Query: 38 LDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + L+ RLQ+AL + + +LH +VH++ + NVLLD + ++ + G Sbjct: 744 LKAGLALETRLQIALDVVEGIRFLHSQ---GLVHRDVKLKNVLLDKQNRAKITDLG 796
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 32.3 bits (72), Expect = 0.31 Identities = 17/64 (26%), Positives = 30/64 (46%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 L YLH + + H++ +P N+LLD +V++++ G + L Y Sbjct: 131 LNYLH---QRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYV 187 Query: 278 APEI 289 APE+ Sbjct: 188 APEV 191
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 32.3 bits (72), Expect = 0.31 Identities = 19/74 (25%), Positives = 34/74 (45%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALL 268 A+ L+ L VVH++ +P N+L+++R V++ + G G + Sbjct: 122 AETLDGLASAHRAGVVHRDIKPENILINDRGHVQITDFG-LAKAASQATLSSTGMLLGTA 180 Query: 269 NYEAPEIQESXTFT 310 Y APE+ E+ T Sbjct: 181 AYLAPEMIENNQAT 194
>RK_RAT (Q63651) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 564 Score = 32.0 bits (71), Expect = 0.40 Identities = 14/36 (38%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LE+LH + +V+++ +P NVLLDN ++R+++ G Sbjct: 305 LEHLH---QRRIVYRDLKPENVLLDNDGNIRISDLG 337
>RK_MOUSE (Q9WVL4) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 564 Score = 32.0 bits (71), Expect = 0.40 Identities = 14/36 (38%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LE+LH + +V+++ +P NVLLDN ++R+++ G Sbjct: 305 LEHLH---QRRIVYRDLKPENVLLDNDGNIRISDLG 337
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 32.0 bits (71), Expect = 0.40 Identities = 14/36 (38%), Positives = 25/36 (69%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +EY H VVH++ +P N+LLD++ +V++A+ G Sbjct: 153 VEYCHRNM---VVHRDLKPENLLLDSKCNVKIADFG 185
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 32.0 bits (71), Expect = 0.40 Identities = 9/25 (36%), Positives = 22/25 (88%) Frame = +2 Query: 131 VVHQNFEPSNVLLDNRFSVRVAECG 205 +VH++ +P N+LLD+++++++A+ G Sbjct: 152 IVHRDLKPENLLLDHKYNIKIADFG 176
>TOPK_HUMAN (Q96KB5) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3) Length = 322 Score = 32.0 bits (71), Expect = 0.40 Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 2/70 (2%) Frame = +2 Query: 2 RTLHDVLHER-EDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNR 178 ++L+D++ ER + L+VAL A+ L+YLH E ++H + + SNV++ Sbjct: 121 KSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQ--EKKLLHGDIKSSNVVIKGD 178 Query: 179 F-SVRVAECG 205 F ++++ + G Sbjct: 179 FETIKICDVG 188
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 32.0 bits (71), Expect = 0.40 Identities = 15/65 (23%), Positives = 28/65 (43%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNY 274 ALEYLH ++H++ +P N+LL+ +++ + G Y Sbjct: 192 ALEYLHGK---GIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQY 248 Query: 275 EAPEI 289 +PE+ Sbjct: 249 VSPEL 253
>CTK1_YEAST (Q03957) CTD kinase subunit alpha (EC 2.7.11.23) (CTD kinase 58 kDa| subunit) (CTDK-I alpha subunit) Length = 528 Score = 32.0 bits (71), Expect = 0.40 Identities = 12/36 (33%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +EYLHD ++H++ + SN+L+DN+ ++++ + G Sbjct: 294 MEYLHDN---KILHRDVKGSNILIDNQGNLKITDFG 326
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 32.0 bits (71), Expect = 0.40 Identities = 15/65 (23%), Positives = 28/65 (43%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNY 274 ALEYLH ++H++ +P N+LL+ +++ + G Y Sbjct: 195 ALEYLHGK---GIIHRDLKPENILLNEDMHIQITDFGTAKVLSPDSKQARANSFVGTAQY 251 Query: 275 EAPEI 289 +PE+ Sbjct: 252 VSPEL 256
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 32.0 bits (71), Expect = 0.40 Identities = 15/65 (23%), Positives = 28/65 (43%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNY 274 ALEYLH ++H++ +P N+LL+ +++ + G Y Sbjct: 195 ALEYLHGK---GIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQY 251 Query: 275 EAPEI 289 +PE+ Sbjct: 252 VSPEL 256
>GRK4_HUMAN (P32298) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) (ITI1) Length = 578 Score = 32.0 bits (71), Expect = 0.40 Identities = 18/68 (26%), Positives = 34/68 (50%) Frame = +2 Query: 107 LHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 L D +V+++ +P N+LLD+R +R+++ G GR+ + Y APE Sbjct: 300 LEDLQRERIVYRDLKPENILLDDRGHIRISDLG--LATEIPEGQRVRGRV-GTVGYMAPE 356 Query: 287 IQESXTFT 310 + + +T Sbjct: 357 VVNNEKYT 364
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 32.0 bits (71), Expect = 0.40 Identities = 22/72 (30%), Positives = 35/72 (48%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H TC VV+++ +P+N+LLD VR+++ G G Y Sbjct: 305 LEHMH-TCF--VVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + T D Sbjct: 358 APEVLQKGTCYD 369
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 32.0 bits (71), Expect = 0.40 Identities = 20/72 (27%), Positives = 34/72 (47%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H+ VV+++ +P+N+LLD VR+++ G G Y Sbjct: 305 LEHMHNRF---VVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + T D Sbjct: 358 APEVLQKGTAYD 369
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 31.6 bits (70), Expect = 0.52 Identities = 18/67 (26%), Positives = 33/67 (49%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL +R + A ++A + +A+ S L Y VH++ +P N+L+D Sbjct: 164 TLLSKFEDRLPEEMARFYLAEMVIAIDSVHQLHY---------VHRDIKPDNILMDMNGH 214 Query: 185 VRVAECG 205 +R+A+ G Sbjct: 215 IRLADFG 221
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 31.6 bits (70), Expect = 0.52 Identities = 11/37 (29%), Positives = 23/37 (62%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++YLH ++H++ +P N+LLD +++ + G Sbjct: 290 AIDYLHSN---GIIHRDIKPENILLDGEMKIKLTDFG 323
>DMPK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 639 Score = 31.6 bits (70), Expect = 0.52 Identities = 20/67 (29%), Positives = 33/67 (49%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL ER + A ++A + +A+ S L Y VH++ +P N+LLD Sbjct: 168 TLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGY---------VHRDIKPDNILLDRCGH 218 Query: 185 VRVAECG 205 +R+A+ G Sbjct: 219 IRLADFG 225
>DMPK_MOUSE (P54265) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 631 Score = 31.6 bits (70), Expect = 0.52 Identities = 20/67 (29%), Positives = 33/67 (49%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL ER + A ++A + +A+ S L Y VH++ +P N+LLD Sbjct: 158 TLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGY---------VHRDIKPDNILLDRCGH 208 Query: 185 VRVAECG 205 +R+A+ G Sbjct: 209 IRLADFG 215
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 31.6 bits (70), Expect = 0.52 Identities = 11/31 (35%), Positives = 21/31 (67%) Frame = +2 Query: 77 ALGSAKALEYLHDTCEPPVVHQNFEPSNVLL 169 A+ A+ + YLHD P++H++ + SN+L+ Sbjct: 246 AVQIARGMNYLHDEAIVPIIHRDLKSSNILI 276
>CDK4_RAT (P35426) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 31.6 bits (70), Expect = 0.52 Identities = 18/70 (25%), Positives = 34/70 (48%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 L++LH C +VH++ +P N+L+ + +V++A+ G + L Y Sbjct: 128 LDFLHANC---IVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALT---PVVVTLWYR 181 Query: 278 APEIQESXTF 307 APE+ T+ Sbjct: 182 APEVLLQSTY 191
>CDK4_PIG (P79432) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 303 Score = 31.6 bits (70), Expect = 0.52 Identities = 18/72 (25%), Positives = 35/72 (48%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLN 271 + L++LH C +VH++ +P N+L+ + +V++A+ G + L Sbjct: 126 RGLDFLHANC---IVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALT---PVVVTLW 179 Query: 272 YEAPEIQESXTF 307 Y APE+ T+ Sbjct: 180 YRAPEVLLQSTY 191
>CDK4_MOUSE (P30285) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) (CRK3) Length = 303 Score = 31.6 bits (70), Expect = 0.52 Identities = 18/70 (25%), Positives = 34/70 (48%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 L++LH C +VH++ +P N+L+ + +V++A+ G + L Y Sbjct: 128 LDFLHANC---IVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALT---PVVVTLWYR 181 Query: 278 APEIQESXTF 307 APE+ T+ Sbjct: 182 APEVLLQSTY 191
>CDK4_HUMAN (P11802) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) (PSK-J3) Length = 303 Score = 31.6 bits (70), Expect = 0.52 Identities = 18/72 (25%), Positives = 35/72 (48%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLN 271 + L++LH C +VH++ +P N+L+ + +V++A+ G + L Sbjct: 126 RGLDFLHANC---IVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALT---PVVVTLW 179 Query: 272 YEAPEIQESXTF 307 Y APE+ T+ Sbjct: 180 YRAPEVLLQSTY 191
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 31.6 bits (70), Expect = 0.52 Identities = 16/36 (44%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LEYLH C+ +VH++ +PSN+LL + V++A+ G Sbjct: 263 LEYLH--CQK-IVHRDIKPSNLLLGDDGHVKIADFG 295
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 31.6 bits (70), Expect = 0.52 Identities = 16/36 (44%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LEYLH C+ +VH++ +PSN+LL + V++A+ G Sbjct: 263 LEYLH--CQK-IVHRDIKPSNLLLGDDGHVKIADFG 295
>KKCC1_HUMAN (Q8N5S9) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 31.6 bits (70), Expect = 0.52 Identities = 16/36 (44%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LEYLH C+ +VH++ +PSN+LL + V++A+ G Sbjct: 263 LEYLH--CQK-IVHRDIKPSNLLLGDDGHVKIADFG 295
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 31.6 bits (70), Expect = 0.52 Identities = 15/63 (23%), Positives = 37/63 (58%), Gaps = 3/63 (4%) Frame = +2 Query: 26 EREDLDSALSWIARL---QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVA 196 +R + S +W L ++A G L++L+ + ++H++ +PSNVL++++ +++ Sbjct: 291 QRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYK--IIHRDIKPSNVLINSKGQIKLC 348 Query: 197 ECG 205 + G Sbjct: 349 DFG 351
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 31.2 bits (69), Expect = 0.69 Identities = 13/45 (28%), Positives = 27/45 (60%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A + L YLH E V+H++ +P N+LL+ + +++ + G Sbjct: 321 KIAESVLRGLSYLH---ERKVIHRDIKPQNILLNEKGEIKLCDFG 362
>CDK4_XENLA (Q91727) Cell division protein kinase 4 (EC 2.7.11.22)| (Cyclin-dependent kinase 4) Length = 319 Score = 31.2 bits (69), Expect = 0.69 Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Frame = +2 Query: 23 HEREDLDSALSWIARLQVALGSAK--------ALEYLHDTCEPPVVHQNFEPSNVLLDNR 178 H +DL + LS + + L + K LE+LH C +VH++ +P N+L+ + Sbjct: 95 HVDQDLKTYLSKVPPPGLPLETIKDLMKQFLSGLEFLHLNC---IVHRDLKPENILVTSG 151 Query: 179 FSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTF 307 V++A+ G + L Y APE+ T+ Sbjct: 152 GQVKLADFGLARIYSCQMALT---PVVVTLWYRAPEVLLQSTY 191
>AURKB_PIG (Q9N0X0) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-B) (Fragment) Length = 156 Score = 31.2 bits (69), Expect = 0.69 Identities = 21/76 (27%), Positives = 35/76 (46%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALL 268 A AL Y H V+H++ +P N+LL + +++A+ G MR L Sbjct: 36 ADALIYCHGK---KVIHRDIKPENLLLGLQGELKIADFGWSVHAPSLRRKT----MRGTL 88 Query: 269 NYEAPEIQESXTFTDR 316 +Y PE+ E T ++ Sbjct: 89 DYLPPEMIEGRTHNEK 104
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 31.2 bits (69), Expect = 0.69 Identities = 13/39 (33%), Positives = 26/39 (66%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + A++Y HD VVH++ + N+LLD F++++++ G Sbjct: 121 SSAIKYCHDL---DVVHRDLKSENLLLDKDFNIKLSDFG 156
>YPC2_CAEEL (Q11179) Putative serine/threonine-protein kinase C05D10.2 in| chromosome III (EC 2.7.11.24) Length = 470 Score = 31.2 bits (69), Expect = 0.69 Identities = 24/91 (26%), Positives = 41/91 (45%) Frame = +2 Query: 8 LHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSV 187 LH+V+ + S L + + + +A+ +LH V+H++ +PSNVLLD V Sbjct: 99 LHNVIKK----GSILKDVHKQYIMCQLFRAIRFLHSG---NVLHRDLKPSNVLLDADCRV 151 Query: 188 RVAECGXXXXXXXXXXXXXXGRMRALLNYEA 280 ++A+ G +M L Y A Sbjct: 152 KLADFGLARSLSSLEDYPEGQKMPDLTEYVA 182
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 31.2 bits (69), Expect = 0.69 Identities = 17/94 (18%), Positives = 40/94 (42%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL D++H D + +++ + +AL + H ++H++ +P+N+++ + Sbjct: 99 TLRDIVHT----DGPMPPQQAIEIVADACQALNFSHQN---GIIHRDVKPANIMISATNA 151 Query: 185 VRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 V+V + G + Y +PE Sbjct: 152 VKVMDFGIARAIADSTSVTQTAAVIGTAQYLSPE 185
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 31.2 bits (69), Expect = 0.69 Identities = 19/69 (27%), Positives = 32/69 (46%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALL 268 A AL Y H V+H++ +P N+LL + +++A+ G G L Sbjct: 234 ANALSYCHSK---RVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCG----TL 286 Query: 269 NYEAPEIQE 295 +Y+ PE+ E Sbjct: 287 DYQPPEMIE 295
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 31.2 bits (69), Expect = 0.69 Identities = 14/45 (31%), Positives = 26/45 (57%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A + L YLH E V+H++ +P N+LL+ V++ + G Sbjct: 328 KIAEAVLRGLSYLH---EKKVIHRDIKPQNILLNENGQVKLCDFG 369
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 31.2 bits (69), Expect = 0.69 Identities = 20/76 (26%), Positives = 35/76 (46%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALL 268 A AL YLH + V+H++ +P N+LL +++++ G G L Sbjct: 197 ANALSYLH---KKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTTLCG----TL 249 Query: 269 NYEAPEIQESXTFTDR 316 +Y PE+ E T++ Sbjct: 250 DYLPPEMVEGKEHTEK 265
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 30.8 bits (68), Expect = 0.89 Identities = 13/37 (35%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H VVH++ + N+LLDN ++++A+ G Sbjct: 129 AVDYCHGR---KVVHRDLKAENLLLDNNMNIKIADFG 162
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 30.8 bits (68), Expect = 0.89 Identities = 12/38 (31%), Positives = 25/38 (65%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +A+ +LH +VH++ +P N+LLD+ +R+++ G Sbjct: 139 EAVSFLHAN---NIVHRDLKPENILLDDNMQIRLSDFG 173
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 30.8 bits (68), Expect = 0.89 Identities = 12/38 (31%), Positives = 25/38 (65%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +A+ +LH +VH++ +P N+LLD+ +R+++ G Sbjct: 139 EAVSFLHAN---NIVHRDLKPENILLDDNMQIRLSDFG 173
>GUC2C_PIG (P55204) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1073 Score = 30.8 bits (68), Expect = 0.89 Identities = 14/52 (26%), Positives = 27/52 (51%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + W ++ V AK + YLH + VH + +N ++D+R V++ + G Sbjct: 585 MDWEFKISVLYDIAKGMSYLHSS--KTEVHGRLKSTNCVVDSRMVVKITDFG 634
>GUC2C_HUMAN (P25092) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR) Length = 1073 Score = 30.8 bits (68), Expect = 0.89 Identities = 14/52 (26%), Positives = 27/52 (51%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + W ++ V AK + YLH + VH + +N ++D+R V++ + G Sbjct: 585 MDWEFKISVLYDIAKGMSYLHSS--KTEVHGRLKSTNCVVDSRMVVKITDFG 634
>PAK1_YEAST (P38990) Serine/threonine-protein kinase PAK1 (EC 2.7.11.1)| Length = 1142 Score = 30.8 bits (68), Expect = 0.89 Identities = 15/54 (27%), Positives = 31/54 (57%) Frame = +2 Query: 44 SALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 S LS+ ++ G LEYLH ++H++ +P+N+L+ +V++++ G Sbjct: 247 SLLSFQETREILRGVVLGLEYLH---YQGIIHRDIKPANLLISGDGTVKISDFG 297
>SWE1_YEAST (P32944) Mitosis inhibitor protein kinase SWE1 (EC 2.7.11.1)| Length = 819 Score = 30.8 bits (68), Expect = 0.89 Identities = 15/63 (23%), Positives = 38/63 (60%) Frame = +2 Query: 17 VLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVA 196 V+ +++ L+ W ++++L AL ++HD+C +VH + +P+NV++ ++++ Sbjct: 543 VIAKKKRLEDWRIWKIIVELSL----ALRFIHDSCH--IVHLDLKPANVMITFEGNLKLG 596 Query: 197 ECG 205 + G Sbjct: 597 DFG 599
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 30.8 bits (68), Expect = 0.89 Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Frame = +2 Query: 71 QVALGSAKALEYLHDTC-------EPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 Q A+A+ Y + C +V+++ +P N+LLD+ +R+++ G Sbjct: 280 QAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLG--LTVHVP 337 Query: 230 XXXXXXGRMRALLNYEAPEIQESXTFT 310 GR+ + Y APE+ ++ +T Sbjct: 338 EGQTIKGRV-GTVGYMAPEVVKNERYT 363
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 30.8 bits (68), Expect = 0.89 Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Frame = +2 Query: 71 QVALGSAKALEYLHDTC-------EPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 Q A+A+ Y + C +V+++ +P N+LLD+ +R+++ G Sbjct: 280 QAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLG--LAVHVP 337 Query: 230 XXXXXXGRMRALLNYEAPEIQESXTFT 310 GR+ + Y APE+ ++ +T Sbjct: 338 EGQTIKGRV-GTVGYMAPEVVKNERYT 363
>SHK2_SCHPO (Q10056) Serine/threonine-protein kinase shk2 (EC 2.7.11.1)| Length = 589 Score = 30.8 bits (68), Expect = 0.89 Identities = 12/45 (26%), Positives = 28/45 (62%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++ L + K +++LH ++H++ + NVLLDN ++++ + G Sbjct: 413 RICLETCKGIQHLHAR---NIIHRDIKSDNVLLDNSGNIKITDFG 454
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 30.8 bits (68), Expect = 0.89 Identities = 20/67 (29%), Positives = 32/67 (47%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL ++ D A +I + +A+ S L Y VH++ +P NVLLD Sbjct: 163 TLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHY---------VHRDIKPDNVLLDVNGH 213 Query: 185 VRVAECG 205 +R+A+ G Sbjct: 214 IRLADFG 220
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 30.8 bits (68), Expect = 0.89 Identities = 12/37 (32%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H C +VH++ + N+LLD ++++A+ G Sbjct: 169 AVQYCHQKC---IVHRDLKAENLLLDADMNIKIADFG 202
>DSOR1_DROME (Q24324) Dual specificity mitogen-activated protein kinase kinase| dSOR1 (EC 2.7.12.2) (Downstream of RAF) (MAPKK) Length = 396 Score = 30.8 bits (68), Expect = 0.89 Identities = 12/45 (26%), Positives = 27/45 (60%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++ L K L YL D ++H++ +PSN+L+++ +++ + G Sbjct: 187 RITLAVLKGLSYLRDN--HAIIHRDVKPSNILVNSSGEIKICDFG 229
>CLA4_ASHGO (Q9HFW2) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 793 Score = 30.8 bits (68), Expect = 0.89 Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 3/70 (4%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVAL---GSAKALEYLHDTCEPPVVHQNFEPSNVLLDN 175 +L DV+ D++ S + Q+A + + L++LHD ++H++ + NVLLD Sbjct: 598 SLTDVIENSIGSDASESPMTEPQIAYIVRETCQGLKFLHDK---HIIHRDIKSDNVLLDT 654 Query: 176 RFSVRVAECG 205 V++ + G Sbjct: 655 HGRVKITDFG 664
>CHK1_CAEBR (Q61RA2) Serine/threonine-protein kinase chk-1 (EC 2.7.11.1)| Length = 493 Score = 30.8 bits (68), Expect = 0.89 Identities = 16/66 (24%), Positives = 32/66 (48%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLN 271 + L+Y+HD C+ +VH++ +P N+LL +++++ G + Sbjct: 136 EGLKYIHD-CD--IVHRDIKPENLLLTTSHVLKISDFGMATLYRNEGKERLLDLSCGTIP 192 Query: 272 YEAPEI 289 Y APE+ Sbjct: 193 YAAPEV 198
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 30.8 bits (68), Expect = 0.89 Identities = 12/37 (32%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H C +VH++ + N+LLD ++++A+ G Sbjct: 169 AVQYCHQKC---IVHRDLKAENLLLDADMNIKIADFG 202
>TESK1_HUMAN (Q15569) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 626 Score = 30.8 bits (68), Expect = 0.89 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLL---DNRFSVRVAECG 205 LSW RL +AL A+ L YLH V H++ N L+ D F+ V + G Sbjct: 147 LSWPVRLHLALDIARGLRYLH---SKGVFHRDLTSKNCLVRREDRGFTAVVGDFG 198
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 30.8 bits (68), Expect = 0.89 Identities = 20/67 (29%), Positives = 32/67 (47%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL ++ D A +I + +A+ S L Y VH++ +P NVLLD Sbjct: 163 TLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHY---------VHRDIKPDNVLLDVNGH 213 Query: 185 VRVAECG 205 +R+A+ G Sbjct: 214 IRLADFG 220
>MRCKB_MOUSE (Q7TT50) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 30.8 bits (68), Expect = 0.89 Identities = 20/67 (29%), Positives = 32/67 (47%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 TL ++ D A +I + +A+ S L Y VH++ +P NVLLD Sbjct: 163 TLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHY---------VHRDIKPDNVLLDVNGH 213 Query: 185 VRVAECG 205 +R+A+ G Sbjct: 214 IRLADFG 220
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 30.8 bits (68), Expect = 0.89 Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 2/69 (2%) Frame = +2 Query: 5 TLHDVLHEREDLDSA--LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNR 178 +L +VL+E + W ++ V AK + YLH + VH + +N ++D+R Sbjct: 571 SLREVLNETISYPDGTIMGWEFKISVLYDIAKGMSYLHSS--KIEVHGRLKSTNCVVDSR 628 Query: 179 FSVRVAECG 205 V++ + G Sbjct: 629 MVVKITDFG 637
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 30.8 bits (68), Expect = 0.89 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H VVH++ +P NVLLD + + ++A+ G Sbjct: 126 AVDYCH---RHMVVHRDLKPENVLLDAQMNAKIADFG 159
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 30.8 bits (68), Expect = 0.89 Identities = 14/37 (37%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H VVH++ +P NVLLD + + ++A+ G Sbjct: 126 AVDYCH---RHMVVHRDLKPENVLLDAQMNAKIADFG 159
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/38 (31%), Positives = 25/38 (65%) Frame = +2 Query: 92 KALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +A+ +LH +VH++ +P N+LLD+ +R+++ G Sbjct: 139 EAVNFLHVN---NIVHRDLKPENILLDDNMQIRLSDFG 173
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/37 (32%), Positives = 23/37 (62%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ALEYLH +++++ +P N+LLD +++ + G Sbjct: 198 ALEYLHSK---DIIYRDLKPENILLDKNGHIKITDFG 231
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/37 (32%), Positives = 26/37 (70%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ALE+LH + +V+++ +P N+L+DN+ +++ + G Sbjct: 446 ALEFLH---KQNIVYRDLKPENLLIDNQGHIKITDFG 479
>TLK2_MOUSE (O55047) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) Length = 718 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/27 (44%), Positives = 21/27 (77%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDN 175 AL+YL++ +PP++H + +P N+LL N Sbjct: 523 ALKYLNEI-KPPIIHYDLKPGNILLVN 548
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/37 (32%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H +VH++ + N+LLDN ++++A+ G Sbjct: 129 AVDYCHGR---KIVHRDLKAENLLLDNNMNIKIADFG 162
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 30.4 bits (67), Expect = 1.2 Identities = 20/87 (22%), Positives = 39/87 (44%), Gaps = 7/87 (8%) Frame = +2 Query: 71 QVALGSAKALEYLHDTC-------EPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXX 229 Q A+A+ Y + C +V+++ +P N+LLD+ +R+++ G Sbjct: 280 QAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLG--LAVHVP 337 Query: 230 XXXXXXGRMRALLNYEAPEIQESXTFT 310 GR+ + Y APE+ + +T Sbjct: 338 EGQTIKGRV-GTVGYMAPEVVRNERYT 363
>TLK2_HUMAN (Q86UE8) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) (PKU-alpha) Length = 772 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/27 (44%), Positives = 21/27 (77%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDN 175 AL+YL++ +PP++H + +P N+LL N Sbjct: 577 ALKYLNEI-KPPIIHYDLKPGNILLVN 602
>WRK19_ARATH (Q9SZ67) Probable WRKY transcription factor 19 (WRKY DNA-binding| protein 19) Length = 1895 Score = 30.4 bits (67), Expect = 1.2 Identities = 19/62 (30%), Positives = 35/62 (56%) Frame = +2 Query: 20 LHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 L++R L ++ + Q+ G L+YLHD +H+N + +NVL+D +V++A+ Sbjct: 1715 LYQRNQLGDSVVSLYTRQILDG----LKYLHDK---GFIHRNIKCANVLVDANGTVKLAD 1767 Query: 200 CG 205 G Sbjct: 1768 FG 1769
>MP2K1_PANTR (Q9XT09) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 167 KVSIAVIKGLTYLRE--KHKIMHRDVQPSNILVNSRGEIKLCDFG 209
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 30.4 bits (67), Expect = 1.2 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H VVH++ +P NVLLD + ++A+ G Sbjct: 126 AVDYCH---RHMVVHRDLKPENVLLDAHMNAKIADFG 159
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 30.4 bits (67), Expect = 1.2 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A++Y H VVH++ +P NVLLD + ++A+ G Sbjct: 126 AVDYCH---RHMVVHRDLKPENVLLDAHMNAKIADFG 159
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 30.4 bits (67), Expect = 1.2 Identities = 19/46 (41%), Positives = 26/46 (56%) Frame = +2 Query: 68 LQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LQVA G +EYL E VH++ N +LD F+V+VA+ G Sbjct: 1167 LQVACG----MEYL---AEQKFVHRDLAARNCMLDESFTVKVADFG 1205
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 30.4 bits (67), Expect = 1.2 Identities = 16/46 (34%), Positives = 25/46 (54%) Frame = +2 Query: 68 LQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + L A+ +EYL E VH++ N +LD F+V+VA+ G Sbjct: 1186 ISFGLQVARGMEYL---AEQKFVHRDLAARNCMLDESFTVKVADFG 1228
>SRK1_SCHPO (O94547) Serine/threonine-protein kinase srk1 (EC 2.7.11.1)| (Sty1-regulated kinase 1) Length = 580 Score = 30.4 bits (67), Expect = 1.2 Identities = 13/29 (44%), Positives = 20/29 (68%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDN 175 A A+ YLH+ C VVH++ +P N+L D+ Sbjct: 241 AHAIRYLHEDCG--VVHRDIKPENLLFDS 267
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 30.4 bits (67), Expect = 1.2 Identities = 12/37 (32%), Positives = 23/37 (62%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ALEYLH +++++ +P N+LLD +++ + G Sbjct: 197 ALEYLHSK---DIIYRDLKPENILLDKNGHIKITDFG 230
>CDK7_CARAU (P51953) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 344 Score = 30.4 bits (67), Expect = 1.2 Identities = 14/42 (33%), Positives = 28/42 (66%) Frame = +2 Query: 80 LGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L S + LEY+H+ ++H++ +P+N+LLD +++A+ G Sbjct: 118 LMSLQGLEYMHNHW---ILHRDLKPNNLLLDENGVLKLADFG 156
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 30.0 bits (66), Expect = 1.5 Identities = 13/39 (33%), Positives = 26/39 (66%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + A++Y HD VVH++ + N+LLD F++++++ G Sbjct: 121 SSAVKYCHDL---DVVHRDLKCENLLLDKDFNIKLSDFG 156
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 30.0 bits (66), Expect = 1.5 Identities = 13/37 (35%), Positives = 23/37 (62%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A+EY HD +VH++ + N+LLD +++A+ G Sbjct: 136 AVEYCHDH---HIVHRDLKTENLLLDGNMDIKLADFG 169
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 30.0 bits (66), Expect = 1.5 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 161 KVSIAVIKGLTYLRE--KHKIMHRDVKPSNILVNSRGEIKLCDFG 203
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 30.0 bits (66), Expect = 1.5 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Frame = +2 Query: 5 TLHDVLHEREDLD-----SALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLL 169 +L++VLH E L A+SW LQ + G A YLH ++H++ +P N+LL Sbjct: 111 SLYNVLHGAEPLPYYTAAHAMSWC--LQCSQGVA----YLHSMQPKALIHRDLKPPNLLL 164
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 30.0 bits (66), Expect = 1.5 Identities = 16/62 (25%), Positives = 27/62 (43%) Frame = +2 Query: 131 VVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYEAPEIQESXTFT 310 VVH++ N+L+ N + +VA+ G +R + APE +S FT Sbjct: 338 VVHRDLRADNILVANDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFT 397 Query: 311 DR 316 + Sbjct: 398 SK 399
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 30.0 bits (66), Expect = 1.5 Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Frame = +2 Query: 38 LDSALSWIARL------QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAE 199 LD L + RL ++++ + L YL D E ++H++ +PSN+L+++ +++ + Sbjct: 156 LDIVLKKVGRLPEKFVGRISVAVVRGLTYLKD--EIKILHRDVKPSNMLVNSNGEIKLCD 213 Query: 200 CGXXXXXXXXXXXXXXGRMRALLNYEAPE 286 G G +Y APE Sbjct: 214 FGVSGMLIDSMANSFVGTR----SYMAPE 238
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 30.0 bits (66), Expect = 1.5 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Frame = +2 Query: 5 TLHDVLHEREDLD-----SALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLL 169 +L++VLH E L A+SW LQ + G A YLH ++H++ +P N+LL Sbjct: 111 SLYNVLHGAEPLPYYTAAHAMSWC--LQCSQGVA----YLHSMQPKALIHRDLKPPNLLL 164
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 30.0 bits (66), Expect = 1.5 Identities = 18/73 (24%), Positives = 35/73 (47%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALL 268 ++AL YLH ++H++ +P N+LL ++++++ G G M Sbjct: 207 SEALLYLHGK---NIIHRDIKPENILLHFNDTIKISDFGWSVHAPSNRRSTLCGTM---- 259 Query: 269 NYEAPEIQESXTF 307 +Y PEI +S + Sbjct: 260 DYLPPEIVQSRPY 272
>GUC2D_RAT (P51839) Olfactory guanylyl cyclase GC-D precursor (EC 4.6.1.2)| (Guanylate cyclase, olfactory) Length = 1110 Score = 30.0 bits (66), Expect = 1.5 Identities = 18/67 (26%), Positives = 30/67 (44%) Frame = +2 Query: 5 TLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFS 184 +L D+L D L W + + L + L YLH P H + N ++D RF Sbjct: 636 SLEDLLRNE---DLRLDWTFKASLLLDLIRGLRYLHHRHFP---HGRLKSRNCVVDTRFV 689 Query: 185 VRVAECG 205 +++ + G Sbjct: 690 LKITDHG 696
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 30.0 bits (66), Expect = 1.5 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H+ VV+++ +P+N+LLD VR+++ G G Y Sbjct: 305 LEHMHNRF---VVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + D Sbjct: 358 APEVLQKGVAYD 369
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 30.0 bits (66), Expect = 1.5 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H+ VV+++ +P+N+LLD VR+++ G G Y Sbjct: 305 LEHMHNRF---VVYRDLKPANILLDEHGHVRISDLGLACDFSKKRPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + D Sbjct: 358 APEVLQKGVAYD 369
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 30.0 bits (66), Expect = 1.5 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H+ VV+++ +P+N+LLD VR+++ G G Y Sbjct: 305 LEHMHNRF---VVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + D Sbjct: 358 APEVLQKGVAYD 369
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 30.0 bits (66), Expect = 1.5 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H+ VV+++ +P+N+LLD VR+++ G G Y Sbjct: 305 LEHMHNRF---VVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + D Sbjct: 358 APEVLQKGVAYD 369
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 30.0 bits (66), Expect = 1.5 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H+ VV+++ +P+N+LLD VR+++ G G Y Sbjct: 305 LEHMHNRF---VVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + D Sbjct: 358 APEVLQKGVAYD 369
>MPK5_ARATH (Q39025) Mitogen-activated protein kinase homolog 5 (EC 2.7.11.24)| (MAP kinase 5) (AtMPK5) Length = 376 Score = 30.0 bits (66), Expect = 1.5 Identities = 16/66 (24%), Positives = 34/66 (51%) Frame = +2 Query: 8 LHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSV 187 LH ++ + L+ Q+ G L+Y+H V+H++ +PSN+LL++ + Sbjct: 131 LHQIIRSNQSLNDDHCQYFLYQILRG----LKYIHSA---NVLHRDLKPSNLLLNSNCDL 183 Query: 188 RVAECG 205 ++ + G Sbjct: 184 KITDFG 189
>KDC1_DROME (P16911) Protein kinase DC1 (EC 2.7.11.1)| Length = 376 Score = 30.0 bits (66), Expect = 1.5 Identities = 13/39 (33%), Positives = 26/39 (66%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 A ALEY+H + +++++ +P N+LLD R +++ + G Sbjct: 153 ALALEYMH---KMHLMYRDLKPENILLDQRGYIKITDFG 188
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 30.0 bits (66), Expect = 1.5 Identities = 9/25 (36%), Positives = 21/25 (84%) Frame = +2 Query: 131 VVHQNFEPSNVLLDNRFSVRVAECG 205 +VH++ +P N+LLD+ +++++A+ G Sbjct: 148 IVHRDLKPENLLLDSFYNIKIADFG 172
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 30.0 bits (66), Expect = 1.5 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 167 KVSIAVIKGLTYLRE--KHKIMHRDVKPSNILVNSRGEIKLCDFG 209
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 30.0 bits (66), Expect = 1.5 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 167 KVSIAVIKGLTYLRE--KHKIMHRDVKPSNILVNSRGEIKLCDFG 209
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 30.0 bits (66), Expect = 1.5 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 167 KVSIAVIKGLTYLRE--KHKIMHRDVKPSNILVNSRGEIKLCDFG 209
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 30.0 bits (66), Expect = 1.5 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 167 KVSIAVIKGLTYLRE--KHKIMHRDVKPSNILVNSRGEIKLCDFG 209
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 30.0 bits (66), Expect = 1.5 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 167 KVSIAVIKGLTYLRE--KHKIMHRDVKPSNILVNSRGEIKLCDFG 209
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 30.0 bits (66), Expect = 1.5 Identities = 14/36 (38%), Positives = 25/36 (69%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LE++H+ VV+++ +P+N+LLD VRV++ G Sbjct: 306 LEHMHNRF---VVYRDLKPANILLDENGHVRVSDLG 338
>TESK1_RAT (Q63572) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 628 Score = 30.0 bits (66), Expect = 1.5 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLL---DNRFSVRVAECG 205 LSW RL +AL A+ L YLH V H++ N L+ D F+ V + G Sbjct: 142 LSWPVRLHLALDIAQGLRYLH---AKGVFHRDLTSKNCLVRREDGGFTAVVGDFG 193
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 30.0 bits (66), Expect = 1.5 Identities = 18/55 (32%), Positives = 31/55 (56%) Frame = +2 Query: 41 DSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 D A +IA L +AL E+LHD +V+++ +P N+LLD ++ + + G Sbjct: 512 DRAKFYIAELVLAL------EHLHDN---DIVYRDLKPENILLDANGNIALCDFG 557
>RK_BOVIN (P28327) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 561 Score = 30.0 bits (66), Expect = 1.5 Identities = 13/36 (36%), Positives = 26/36 (72%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 LE+LH + +++++ +P NVLLD+ +VR+++ G Sbjct: 302 LEHLH---QRNIIYRDLKPENVLLDDDGNVRISDLG 334
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 30.0 bits (66), Expect = 1.5 Identities = 19/72 (26%), Positives = 33/72 (45%) Frame = +2 Query: 98 LEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECGXXXXXXXXXXXXXXGRMRALLNYE 277 LE++H+ VV+++ +P+N+LLD R+++ G G Y Sbjct: 305 LEHVHNRF---VVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTH----GYM 357 Query: 278 APEIQESXTFTD 313 APE+ + T D Sbjct: 358 APEVLQKGTAYD 369
>TESK1_MOUSE (O70146) Dual specificity testis-specific protein kinase 1 (EC| 2.7.12.1) (Testicular protein kinase 1) Length = 627 Score = 30.0 bits (66), Expect = 1.5 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Frame = +2 Query: 50 LSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLL---DNRFSVRVAECG 205 LSW RL +AL A+ L YLH V H++ N L+ D F+ V + G Sbjct: 142 LSWPVRLHLALDIAQGLRYLH---AKGVFHRDLTSKNCLVRREDRGFTAVVGDFG 193
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 30.0 bits (66), Expect = 1.5 Identities = 12/45 (26%), Positives = 30/45 (66%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +V++ K L YL + + ++H++ +PSN+L+++R +++ + G Sbjct: 168 KVSIAVIKGLTYLRE--KHKIMHRDVKPSNILVNSRGEIKLCDFG 210
>CI096_MACFA (Q4R793) Protein kinase-like protein C9orf96 homolog| Length = 649 Score = 30.0 bits (66), Expect = 1.5 Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Frame = +2 Query: 8 LHDVLHEREDLDSALSWIARLQVALGSA-KALEYLHDTCEPPVVHQNFEPSNVLL 169 + D +E +DS W +Q LG ALEYLH ++H+N +PSN++L Sbjct: 119 IEDKRKAKEIIDS--KW---MQNVLGQVLDALEYLHHL---DIIHRNLKPSNIIL 165
>PKN1_CORGL (Q8NU98) Probable serine/threonine protein kinase pknB (EC| 2.7.11.1) Length = 646 Score = 29.6 bits (65), Expect = 2.0 Identities = 16/68 (23%), Positives = 35/68 (51%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 R L +V+ E D + + + + +AL+ HD ++H++ +P+N+++ N Sbjct: 96 RNLREVVTE----DGVFTPVEAANILIPVCEALQASHDA---GIIHRDVKPANIMITNTG 148 Query: 182 SVRVAECG 205 V+V + G Sbjct: 149 GVKVMDFG 156
>MK07_HUMAN (Q13164) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase) Length = 815 Score = 29.6 bits (65), Expect = 2.0 Identities = 16/66 (24%), Positives = 34/66 (51%) Frame = +2 Query: 8 LHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSV 187 LH ++H + L L + L + L+Y+H V+H++ +PSN+L++ + Sbjct: 143 LHQIIHSSQPL--TLEHVRYFLYQL--LRGLKYMHSA---QVIHRDLKPSNLLVNENCEL 195 Query: 188 RVAECG 205 ++ + G Sbjct: 196 KIGDFG 201
>CDK7_MOUSE (Q03147) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (Protein-tyrosine kinase MPK-7) (CR4 protein kinas Length = 346 Score = 29.6 bits (65), Expect = 2.0 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +2 Query: 80 LGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + + LEYLH ++H++ +P+N+LLD +++A+ G Sbjct: 119 LMTLQGLEYLHQHW---ILHRDLKPNNLLLDENGVLKLADFG 157
>CDK7_HUMAN (P50613) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) Length = 346 Score = 29.6 bits (65), Expect = 2.0 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +2 Query: 80 LGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + + LEYLH ++H++ +P+N+LLD +++A+ G Sbjct: 119 LMTLQGLEYLHQHW---ILHRDLKPNNLLLDENGVLKLADFG 157
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 29.6 bits (65), Expect = 2.0 Identities = 21/68 (30%), Positives = 32/68 (47%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 R L VL E A+ L++ ALE H E +VH++ +P NV++ R Sbjct: 107 RPLGSVLDEDVRQQGAMPADKALKITADVLAALEISH---EMGLVHRDIKPGNVMMTKRG 163 Query: 182 SVRVAECG 205 V+V + G Sbjct: 164 VVKVMDFG 171
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 29.6 bits (65), Expect = 2.0 Identities = 16/58 (27%), Positives = 28/58 (48%) Frame = +2 Query: 32 EDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 +++DS W R+ A A + YLH ++H++ N L+ +V VA+ G Sbjct: 426 KNMDSQYPWSQRVSFAKDIASGMAYLHSM---NIIHRDLNSHNCLVRENRNVVVADFG 480
>CDK7_XENLA (P20911) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (40 kDa protein kinase) (P40 MO15) (CDC2/CDK2,4-activating kinase) Length = 352 Score = 29.6 bits (65), Expect = 2.0 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +2 Query: 80 LGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + + LEYLH ++H++ +P+N+LLD +++A+ G Sbjct: 125 LMTLQGLEYLHHLW---ILHRDLKPNNLLLDENGVLKLADFG 163
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 29.6 bits (65), Expect = 2.0 Identities = 17/58 (29%), Positives = 27/58 (46%) Frame = +2 Query: 32 EDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + +DS W R+ A A + YLH ++H++ N L+ SV VA+ G Sbjct: 433 KSMDSHYPWSQRVSFAKDIAAGMAYLHSM---NIIHRDLNSHNCLVRENKSVVVADFG 487
>YR62_CAEEL (Q20347) Putative serine/threonine-protein kinase F42G10.2 (EC| 2.7.12.2) Length = 363 Score = 29.6 bits (65), Expect = 2.0 Identities = 13/44 (29%), Positives = 28/44 (63%) Frame = +2 Query: 74 VALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + + + AL+YL E ++H++ +PSN+L+D +V++ + G Sbjct: 173 ITVCTVDALDYLKK--ELKIIHRDVKPSNILVDGTGAVKLCDFG 214
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 29.6 bits (65), Expect = 2.0 Identities = 11/45 (24%), Positives = 28/45 (62%) Frame = +2 Query: 71 QVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++A+ + L YL+D ++H++ +PSN+L++ +++ + G Sbjct: 209 KIAVAVSHGLTYLYDVHR--IIHRDVKPSNILVNGAGQIKICDFG 251
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 29.6 bits (65), Expect = 2.0 Identities = 12/37 (32%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 AL++ H + H++ +P N+LLD + ++R+A+ G Sbjct: 128 ALDFCHSHS---ICHRDLKPENLLLDEKNNIRIADFG 161
>MASTL_MOUSE (Q8C0P0) Microtubule-associated serine/threonine-protein| kinase-like (EC 2.7.11.1) Length = 865 Score = 29.6 bits (65), Expect = 2.0 Identities = 15/57 (26%), Positives = 32/57 (56%) Frame = +2 Query: 35 DLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 D + A+ +I+ + A AL+YLH ++H++ +P N+L+ N +++ + G Sbjct: 128 DEEMAIKYISEV------ALALDYLH---RHGIIHRDLKPDNMLISNEGHIKLTDFG 175
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 29.6 bits (65), Expect = 2.0 Identities = 10/37 (27%), Positives = 22/37 (59%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 ++EY+H ++H++ +P N+L D V++ + G Sbjct: 165 SIEYMHSC---GIIHRDLKPENILFDGNMHVKITDFG 198
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 29.6 bits (65), Expect = 2.0 Identities = 11/25 (44%), Positives = 20/25 (80%) Frame = +2 Query: 131 VVHQNFEPSNVLLDNRFSVRVAECG 205 VVH++ +P N+LLD + +V++A+ G Sbjct: 206 VVHRDLKPENLLLDEQNNVKIADFG 230
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 29.6 bits (65), Expect = 2.0 Identities = 12/39 (30%), Positives = 26/39 (66%) Frame = +2 Query: 89 AKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 + A++Y HD +VH++ + N+LLD F++++++ G Sbjct: 121 SSAVKYCHDL---DIVHRDLKCENLLLDKDFNIKLSDFG 156
>MK07_MOUSE (Q9WVS8) Mitogen-activated protein kinase 7 (EC 2.7.11.24)| (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase) Length = 806 Score = 29.6 bits (65), Expect = 2.0 Identities = 16/66 (24%), Positives = 34/66 (51%) Frame = +2 Query: 8 LHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSV 187 LH ++H + L L + L + L+Y+H V+H++ +PSN+L++ + Sbjct: 144 LHQIIHSSQPL--TLEHVRYFLYQL--LRGLKYMHSA---QVIHRDLKPSNLLVNENCEL 196 Query: 188 RVAECG 205 ++ + G Sbjct: 197 KIGDFG 202
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 29.6 bits (65), Expect = 2.0 Identities = 12/37 (32%), Positives = 24/37 (64%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 AL++ H + H++ +P N+LLD + ++R+A+ G Sbjct: 159 ALDFCHSYS---ICHRDLKPENLLLDEKNNIRIADFG 192
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 29.6 bits (65), Expect = 2.0 Identities = 20/91 (21%), Positives = 37/91 (40%) Frame = +2 Query: 26 EREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 E D+D ++W A AK + YLH V+H++ + NV++ +++ + G Sbjct: 100 EEMDMDHIMTW------ATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFG 153 Query: 206 XXXXXXXXXXXXXXGRMRALLNYEAPEIQES 298 G + APE+ +S Sbjct: 154 ASRFHNHTTHMSLVG----TFPWMAPEVIQS 180
>CDK7_RAT (P51952) Cell division protein kinase 7 (EC 2.7.11.22) (EC| 2.7.11.23) (CDK-activating kinase) (CAK) (TFIIH basal transcription factor complex kinase subunit) (39 protein kinase) (P39 Mo15) (Fragment) Length = 329 Score = 29.6 bits (65), Expect = 2.0 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +2 Query: 80 LGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRVAECG 205 L + + LEYLH ++H++ +P+N+LLD +++A+ G Sbjct: 111 LMTLQGLEYLHQHW---ILHRDLKPNNLLLDENGVLKLADFG 149
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 29.3 bits (64), Expect = 2.6 Identities = 18/68 (26%), Positives = 37/68 (54%) Frame = +2 Query: 2 RTLHDVLHEREDLDSALSWIARLQVALGSAKALEYLHDTCEPPVVHQNFEPSNVLLDNRF 181 R L D++ RED + S A + + + A L + E ++H++ +P+N++++N Sbjct: 96 RDLRDIV--REDGPYSPSQAATIMIPVCHA-----LQSSHEAGIIHRDVKPANIMINNTG 148 Query: 182 SVRVAECG 205 V+V + G Sbjct: 149 GVKVMDFG 156
>NRBP_PONPY (Q5RBH9) Nuclear receptor-binding protein| Length = 535 Score = 29.3 bits (64), Expect = 2.6 Identities = 10/33 (30%), Positives = 20/33 (60%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRV 193 AL YLH +C+PP++H N + + + +++ Sbjct: 187 ALSYLH-SCDPPIIHGNLTCDTIFIQHNGLIKI 218
>NRBP_MOUSE (Q99J45) Nuclear receptor-binding protein (MLF1 adapter molecule)| (HLS7-interacting protein kinase) Length = 535 Score = 29.3 bits (64), Expect = 2.6 Identities = 10/33 (30%), Positives = 20/33 (60%) Frame = +2 Query: 95 ALEYLHDTCEPPVVHQNFEPSNVLLDNRFSVRV 193 AL YLH +C+PP++H N + + + +++ Sbjct: 187 ALSYLH-SCDPPIIHGNLTCDTIFIQHNGLIKI 218 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,879,089 Number of Sequences: 219361 Number of extensions: 705794 Number of successful extensions: 2898 Number of sequences better than 10.0: 463 Number of HSP's better than 10.0 without gapping: 2801 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2877 length of database: 80,573,946 effective HSP length: 81 effective length of database: 62,805,705 effective search space used: 1507336920 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
