ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags25h04 |
|---|---|
| Clone Library Name | barley_pub |
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 308 bits (789), Expect = 7e-84 Identities = 144/185 (77%), Positives = 169/185 (91%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++EVM S+ +I+IV+E VTGGELF+ IA+ GRLKE++ARKYFQQLINAVDYCHSRGVYH Sbjct: 82 RLFEVMGSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRGVYH 141 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+G LKVSDFGLSAL++QV+ DGLLHTTCGTPNYVAPEVI ++GYDGA Sbjct: 142 RDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYDGAA 201 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD+WSCGVIL+VL+AG+LPFED N++ALYKKI +A F+CPSWFST AKKLI +ILDPNP Sbjct: 202 ADIWSCGVILYVLLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDPNPT 261 Query: 542 TRITI 556 TRITI Sbjct: 262 TRITI 266
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 277 bits (709), Expect = 1e-74 Identities = 132/183 (72%), Positives = 157/183 (85%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 ++EVMA+++KIY VME V GGELF+K+ S G+L+ED ARKYFQQL+ AVD+CHSRGV HR Sbjct: 75 LHEVMATKSKIYFVMEHVKGGELFNKV-STGKLREDVARKYFQQLVRAVDFCHSRGVCHR 133 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 DLKPENLLLD +G LK+SDFGLSALS R+DGLLHTTCGTP YVAPEVI+ GYDG KA Sbjct: 134 DLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKA 193 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNT 544 D+WSCGVILFVL+AGYLPF DSNLM LYKKI KA+ P+W + AK+L+K+ILDPNPNT Sbjct: 194 DVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKFPNWLAPGAKRLLKRILDPNPNT 253 Query: 545 RIT 553 R++ Sbjct: 254 RVS 256
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 271 bits (693), Expect = 9e-73 Identities = 121/185 (65%), Positives = 153/185 (82%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EVMA+++KI+ ME V GGELF+KI+ GRL ED +R+YFQQLI+AV YCH+RGVYH Sbjct: 84 KLHEVMATKSKIFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARGVYH 143 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLL+D NG LKVSDFGLSAL+ Q+R DGLLHT CGTP YVAPE+++ KGY+GAK Sbjct: 144 RDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAK 203 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCG++LFVL+AGYLPF D N+M +YKKIYK ++ P W S K+ + ++LD NP Sbjct: 204 VDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPE 263 Query: 542 TRITI 556 TRITI Sbjct: 264 TRITI 268
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 270 bits (691), Expect = 2e-72 Identities = 128/185 (69%), Positives = 155/185 (83%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+YEV+AS +KIYIV+E VTGGELFD+I +GRL+E ++RKYFQQL++AV +CH +GVYH Sbjct: 73 RLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKGVYH 132 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD NG LKVSDFGLSAL Q+ E LL TTCGTPNYVAPEV++ +GYDG+ Sbjct: 133 RDLKPENLLLDTNGNLKVSDFGLSALPQEGVE--LLRTTCGTPNYVAPEVLSGQGYDGSA 190 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD+WSCGVILFV++AGYLPF +++L LY+KI A+FSCP WFS K LI +ILDPNP Sbjct: 191 ADIWSCGVILFVILAGYLPFSETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPK 250 Query: 542 TRITI 556 TRI I Sbjct: 251 TRIQI 255
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 263 bits (673), Expect = 2e-70 Identities = 121/185 (65%), Positives = 152/185 (82%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++EV+AS+TKI +VMELVTGGELFD+I S G+L E D RK FQQLI+ + YCHS+GV+H Sbjct: 82 RLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGVFH 141 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK EN+LLDA G +K++DFGLSAL Q R+DGLLHTTCG+PNYVAPEV+ N+GYDGA Sbjct: 142 RDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDGAA 201 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 +D+WSCGVIL+V++ G LPF+D NL LY+KI K D P W S A+ +IK++LDPNP Sbjct: 202 SDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPNPV 261 Query: 542 TRITI 556 TRIT+ Sbjct: 262 TRITV 266
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 199 bits (507), Expect = 3e-51 Identities = 97/185 (52%), Positives = 132/185 (71%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+YEV+ + T IY+VME V GELFD I +GRL+ED+AR +FQQ+I+ V+YCH V H Sbjct: 104 RLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVH 163 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD+ +K++DFGLS + +R+ L T+CG+PNY APEVI+ K Y G + Sbjct: 164 RDLKPENLLLDSKCNVKIADFGLSNI---MRDGHFLKTSCGSPNYAAPEVISGKLYAGPE 220 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+ L+ G LPF+D N+ L+KKI ++ PS S A+ LI ++L +P Sbjct: 221 VDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPM 280 Query: 542 TRITI 556 R+TI Sbjct: 281 KRVTI 285
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 198 bits (504), Expect = 7e-51 Identities = 97/185 (52%), Positives = 132/185 (71%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R YEV+ + + IY+VME V GELFD I +GRL+ED+AR +FQQ+I+ V+YCH V H Sbjct: 82 RQYEVIETTSDIYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVH 141 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD+ +K++DFGLS + +R+ L T+CG+PNY APEVI+ K Y G + Sbjct: 142 RDLKPENLLLDSRCNIKIADFGLSNV---MRDGHFLKTSCGSPNYAAPEVISGKLYAGPE 198 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+ L+ G LPF+D N+ L+KKI ++ PS S+ A+ LI ++L +P Sbjct: 199 VDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPV 258 Query: 542 TRITI 556 RITI Sbjct: 259 KRITI 263
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 185 bits (469), Expect = 9e-47 Identities = 89/185 (48%), Positives = 129/185 (69%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y V+ ++ KI++V+E GGELFD I S+ RL E++ R F+Q+++AV Y HS+G H Sbjct: 71 QLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGYAH 130 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLL D N LK+ DFGL A + +D L T CG+ Y APE+I K Y G++ Sbjct: 131 RDLKPENLLFDENHKLKLIDFGLCA-KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD+WS G++L+VLM G+LPF+D N+MALYKKI + + P W S S+ L++++L +P Sbjct: 190 ADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYEVPKWLSPSSILLLQQMLQVDPK 249 Query: 542 TRITI 556 RI++ Sbjct: 250 KRISM 254
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 184 bits (468), Expect = 1e-46 Identities = 80/185 (43%), Positives = 129/185 (69%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++++V ++ +Y+V+E V+GGELFD + +GRL +ARK+F+Q+++A+D+CHS + H Sbjct: 111 KLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICH 170 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD ++++DFG+++L D LL T+CG+P+Y PEVI + YDG + Sbjct: 171 RDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIKGEKYDGRR 227 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD+WSCGVILF L+ G LPF+D NL L +K+ + F P + + L++ +++ P Sbjct: 228 ADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPE 287 Query: 542 TRITI 556 R+++ Sbjct: 288 KRLSL 292
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 184 bits (468), Expect = 1e-46 Identities = 90/186 (48%), Positives = 128/186 (68%), Gaps = 1/186 (0%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V H Sbjct: 78 KLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVH 137 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYDGA 358 RDLKPEN+LLDA+ K++DFGLS + DG L T+CG+PNY APEVI+ + Y G Sbjct: 138 RDLKPENVLLDAHMNAKIADFGLS----NIMSDGEFLRTSCGSPNYAAPEVISGRLYAGP 193 Query: 359 KADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 538 + D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L +P Sbjct: 194 EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDP 253 Query: 539 NTRITI 556 R TI Sbjct: 254 LKRATI 259
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 184 bits (466), Expect = 2e-46 Identities = 88/185 (47%), Positives = 126/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y+V+++ + I+++ME V+GGELFD I GRLK +AR++FQQ+I+ VDYCH V H Sbjct: 149 RLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVH 208 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G + Sbjct: 209 RDLKPENLLLDEQNNVKIADFGLSNI---MTDGDFLRTSCGSPNYAAPEVISGKLYAGPE 265 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+ L+ G LPF+D ++ +L++KI F P + L+ +L +P Sbjct: 266 VDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVDPM 325 Query: 542 TRITI 556 R TI Sbjct: 326 KRATI 330
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 184 bits (466), Expect = 2e-46 Identities = 88/185 (47%), Positives = 127/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V H Sbjct: 78 KLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVH 137 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G + Sbjct: 138 RDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE 194 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L +P Sbjct: 195 VDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPL 254 Query: 542 TRITI 556 R TI Sbjct: 255 KRATI 259
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 183 bits (465), Expect = 2e-46 Identities = 88/185 (47%), Positives = 126/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V H Sbjct: 78 KLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVH 137 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA K++DFG LS + + L T+CG+PNY APEVI+ + Y G + Sbjct: 138 RDLKPENVLLDAQMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE 194 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L +P Sbjct: 195 VDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPL 254 Query: 542 TRITI 556 R TI Sbjct: 255 KRATI 259
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 183 bits (464), Expect = 3e-46 Identities = 90/185 (48%), Positives = 130/185 (70%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+ S+ +I +V+E G ELFD I RG++ ED+AR++FQQ+I AV+YCH + H Sbjct: 114 KLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKIVH 172 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G + Sbjct: 173 RDLKPENLLLDDQLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAGPE 229 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+V++ G LPF+D + AL+KKI ++ P++ S AK L+ ++L NP Sbjct: 230 VDVWSSGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVNPL 289 Query: 542 TRITI 556 RITI Sbjct: 290 NRITI 294
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 183 bits (464), Expect = 3e-46 Identities = 82/185 (44%), Positives = 128/185 (69%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++++V ++ +Y+V+E V+GGELFD + +GRL +ARK+F+Q+I+A+D+CHS + H Sbjct: 80 KLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICH 139 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD ++++DFG+++L D LL T+CG+P+Y PEVI + YDG K Sbjct: 140 RDLKPENLLLDEKNNIRIADFGMASLQV---GDSLLETSCGSPHYACPEVIRGEKYDGRK 196 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD+WSCGVILF L+ G LPF+D NL L +K+ + F P + + L++ + + + Sbjct: 197 ADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMSEVDAA 256 Query: 542 TRITI 556 R+T+ Sbjct: 257 RRLTL 261
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 183 bits (464), Expect = 3e-46 Identities = 88/185 (47%), Positives = 126/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ T ++VME V+GGELFD I GR++E +AR+ FQQ+++AVDYCH V H Sbjct: 78 KLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVH 137 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA K++DFG LS + + L T+CG+PNY APEVI+ + Y G + Sbjct: 138 RDLKPENVLLDAQMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE 194 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+ L+ G LPF+D ++ L+KKI F P + + S L+ +L +P Sbjct: 195 VDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVDPL 254 Query: 542 TRITI 556 R TI Sbjct: 255 KRATI 259
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 181 bits (459), Expect = 1e-45 Identities = 87/185 (47%), Positives = 126/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V H Sbjct: 80 KLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVH 139 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G + Sbjct: 140 RDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE 196 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L +P Sbjct: 197 VDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPM 256 Query: 542 TRITI 556 R TI Sbjct: 257 KRATI 261
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 181 bits (459), Expect = 1e-45 Identities = 87/185 (47%), Positives = 126/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V H Sbjct: 80 KLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVH 139 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G + Sbjct: 140 RDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE 196 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L +P Sbjct: 197 VDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPM 256 Query: 542 TRITI 556 R TI Sbjct: 257 KRATI 261
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 181 bits (459), Expect = 1e-45 Identities = 87/185 (47%), Positives = 126/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V H Sbjct: 78 KLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVH 137 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G + Sbjct: 138 RDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE 194 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L +P Sbjct: 195 VDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPM 254 Query: 542 TRITI 556 R TI Sbjct: 255 KRATI 259
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 181 bits (459), Expect = 1e-45 Identities = 88/185 (47%), Positives = 127/185 (68%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y V+ + KI++V+E GGELFD I S+ RL E++ R F+Q+++AV Y HS+G H Sbjct: 71 QLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAH 130 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLL D LK+ DFGL A + +D L T CG+ Y APE+I K Y G++ Sbjct: 131 RDLKPENLLFDEYHKLKLIDFGLCA-KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD+WS G++L+VLM G+LPF+D N+MALYKKI + + P W S S+ L++++L +P Sbjct: 190 ADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPK 249 Query: 542 TRITI 556 RI++ Sbjct: 250 KRISM 254
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 181 bits (459), Expect = 1e-45 Identities = 87/185 (47%), Positives = 124/185 (67%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++ V+++ + I++VMELV+GGELF I +G L ++R+YFQQ+I+ V YCH+ + H Sbjct: 86 RLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVH 145 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLDAN +K++DFG LS + + LL T CG+PNY APE+I+NK Y G + Sbjct: 146 RDLKPENLLLDANKNIKIADFG---LSNYMTDGDLLSTACGSPNYAAPELISNKLYVGPE 202 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLWSCGVIL+ ++ G LPF+D N+ L+ KI ++ P A LI +L +P Sbjct: 203 VDLWSCGVILYAMLCGTLPFDDQNVPTLFAKIKSGRYTVPYSMEKQAADLISTMLQVDPV 262 Query: 542 TRITI 556 R + Sbjct: 263 KRADV 267
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 181 bits (458), Expect = 2e-45 Identities = 85/185 (45%), Positives = 128/185 (69%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+ + T I +V+E GGELFD I + R+ ED+ R++FQQ+I A++YCH + H Sbjct: 96 KLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVH 154 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD N +K++DFGLS + + + L T+CG+PNY APEVIN K Y G + Sbjct: 155 RDLKPENLLLDDNLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVINGKLYAGPE 211 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCG++L+V++ G LPF+D + L+KK+ + P + S A+ LI++++ +P Sbjct: 212 VDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVADPM 271 Query: 542 TRITI 556 RITI Sbjct: 272 QRITI 276
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 180 bits (457), Expect = 2e-45 Identities = 84/184 (45%), Positives = 126/184 (68%), Gaps = 1/184 (0%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 ++EV +++++Y+V+E V GGELFD + S+G+L E +A YF+Q++ V YCHS + HR Sbjct: 179 LFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHR 238 Query: 185 DLKPENLLLDA-NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 DLKPENLLLD N +K++DFG++AL + LL T+CG+P+Y +PE++ + Y G Sbjct: 239 DLKPENLLLDKKNRRIKIADFGMAALELPNK---LLKTSCGSPHYASPEIVMGRPYHGGP 295 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 +D+WSCG++LF L+ G+LPF D N+ L K+ + PS S+ A+ LI KIL +P Sbjct: 296 SDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPE 355 Query: 542 TRIT 553 RIT Sbjct: 356 KRIT 359
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 179 bits (455), Expect = 4e-45 Identities = 90/186 (48%), Positives = 131/186 (70%), Gaps = 1/186 (0%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+ S+ +I +V+E G ELFD I RG++ ED+AR++FQQ+I AV+YCH + H Sbjct: 115 KLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKIVH 173 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYV-APEVINNKGYDGA 358 RDLKPENLLLD +K++DFGLS + + + L T+CG+PNY+ APEVI+ K Y G Sbjct: 174 RDLKPENLLLDDQLNVKIADFGLSNI---MTDGNFLKTSCGSPNYMPAPEVISGKLYAGP 230 Query: 359 KADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 538 + D+WS GVIL+V++ G LPF+D + AL+KKI ++ P++ S AK L+ ++L NP Sbjct: 231 EVDVWSAGVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVVNP 290 Query: 539 NTRITI 556 RITI Sbjct: 291 LNRITI 296
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 179 bits (454), Expect = 5e-45 Identities = 86/185 (46%), Positives = 125/185 (67%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+++ + I++VME V+GGELFD I GRL E ++R+ FQQ+++ VDYCH V H Sbjct: 78 KLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVH 137 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA+ K++DFG LS + + L T+CG+PNY APEVI+ + Y G + Sbjct: 138 RDLKPENVLLDAHMNAKIADFG---LSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE 194 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L+ G LPF+D ++ L+KKI F P + + S L+K +L +P Sbjct: 195 VDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPM 254 Query: 542 TRITI 556 R I Sbjct: 255 KRAAI 259
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 179 bits (453), Expect = 6e-45 Identities = 86/185 (46%), Positives = 128/185 (69%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+ S+ +I +V+E G ELFD I R ++ E +AR++FQQ+I+AV+YCH + H Sbjct: 101 KLYDVIKSKDEIIMVIEYA-GNELFDYIVQRNKMSEQEARRFFQQIISAVEYCHRHKIVH 159 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD + +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G + Sbjct: 160 RDLKPENLLLDEHLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAGPE 216 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+V++ LPF+D ++ L+K I ++ P + S A LIK++L NP Sbjct: 217 VDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGASDLIKRMLIVNPL 276 Query: 542 TRITI 556 RI+I Sbjct: 277 NRISI 281
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 177 bits (450), Expect = 1e-44 Identities = 86/185 (46%), Positives = 128/185 (69%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+V+ S+ +I +V+E G ELFD I R ++ E +AR++FQQ+I+AV+YCH + H Sbjct: 117 KLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVH 175 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD + +K++DFGLS + + + L T+CG+PNY APEVI+ K Y G + Sbjct: 176 RDLKPENLLLDEHLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAPEVISGKLYAGPE 232 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WSCGVIL+V++ LPF+D ++ L+K I ++ P + S A LIK++L NP Sbjct: 233 VDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPL 292 Query: 542 TRITI 556 RI+I Sbjct: 293 NRISI 297
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 177 bits (450), Expect = 1e-44 Identities = 91/186 (48%), Positives = 125/186 (67%), Gaps = 1/186 (0%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+YEV+ + I++VME G+L D I + RL+ED+AR+ FQQ+I+AV+YCH V H Sbjct: 79 RVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCHRNKVVH 138 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYDGA 358 RDLKPENLLLD+ +K++DFGLS V DG L T+CG+ NY APEVI+ K Y G Sbjct: 139 RDLKPENLLLDSKYNVKLADFGLS----NVMHDGHFLKTSCGSLNYAAPEVISGKLYAGP 194 Query: 359 KADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 538 + D+WSCGVIL+ L+ G +PF+D N+ L+KKI + P + S + LI ++L +P Sbjct: 195 EIDVWSCGVILYALLCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRMLIVDP 254 Query: 539 NTRITI 556 RITI Sbjct: 255 MKRITI 260
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 174 bits (442), Expect = 1e-43 Identities = 88/187 (47%), Positives = 123/187 (65%), Gaps = 4/187 (2%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y+V + T +Y+V+E GELF+ + RG L E +A ++F+Q+I V YCH+ G+ H Sbjct: 95 RLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVH 154 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLLD +K++DFG++AL E LL T+CG+P+Y APE+++ Y G Sbjct: 155 RDLKPENLLLDHKYNIKIADFGMAALE---TEGKLLETSCGSPHYAAPEIVSGIPYQGFA 211 Query: 362 ADLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFSCPS--WFSTSAKKLIKKILD 529 +D+WSCGVILF L+ G LPF ED N+ L K+ K +F PS S A+ LI+KIL Sbjct: 212 SDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILT 271 Query: 530 PNPNTRI 550 +P RI Sbjct: 272 VDPERRI 278
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 174 bits (441), Expect = 2e-43 Identities = 75/185 (40%), Positives = 128/185 (69%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ +V++++ ++++V+E + GGELFD + +G E D K+ Q++ ++YCH + H Sbjct: 72 QLIDVISAQEQLFVVVEYMPGGELFDCMLRKGSFTEQDTAKFLWQILCGLEYCHKLHICH 131 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL LDA+G++K+ +FG++++ Q + LL T+CG+P+Y +PE+I + YDG Sbjct: 132 RDLKPENLYLDAHGSIKIGEFGMASIQQPGK---LLQTSCGSPHYASPEIIMGRSYDGCA 188 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 +D+WSCG+I F L+ G LPF+D N+ +L K+ + F PS S A+ L+ ++LD + + Sbjct: 189 SDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQGQFEMPSNISPQAQHLLYRMLDVDSS 248 Query: 542 TRITI 556 TRIT+ Sbjct: 249 TRITM 253
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 172 bits (435), Expect = 7e-43 Identities = 80/185 (43%), Positives = 122/185 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + H Sbjct: 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVH 173 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 174 RDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPE 230 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK L NP+ Sbjct: 231 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS 290 Query: 542 TRITI 556 R T+ Sbjct: 291 KRGTL 295
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 172 bits (435), Expect = 7e-43 Identities = 80/185 (43%), Positives = 122/185 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + H Sbjct: 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVH 173 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 174 RDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPE 230 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK L NP+ Sbjct: 231 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS 290 Query: 542 TRITI 556 R T+ Sbjct: 291 KRGTL 295
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 170 bits (431), Expect = 2e-42 Identities = 79/182 (43%), Positives = 120/182 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + H Sbjct: 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVH 180 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 181 RDLKAENLLLDADMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 237 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK+L NP Sbjct: 238 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLNPI 297 Query: 542 TR 547 R Sbjct: 298 KR 299
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 170 bits (431), Expect = 2e-42 Identities = 79/182 (43%), Positives = 120/182 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + H Sbjct: 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVH 180 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 181 RDLKAENLLLDADMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 237 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK+L NP Sbjct: 238 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCENLLKKLLVLNPI 297 Query: 542 TR 547 R Sbjct: 298 KR 299
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 169 bits (429), Expect = 4e-42 Identities = 78/185 (42%), Positives = 121/185 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y++ME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + H Sbjct: 117 KLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVH 176 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 177 RDLKAENLLLDADMNIKIADFG---FSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPE 233 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+K+ L NP Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPV 293 Query: 542 TRITI 556 R T+ Sbjct: 294 KRGTL 298
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 169 bits (429), Expect = 4e-42 Identities = 78/185 (42%), Positives = 121/185 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y++ME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + H Sbjct: 117 KLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVH 176 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 177 RDLKAENLLLDADMNIKITDFG---FSNEFTVGSKLDTFCGSPPYAAPELFQGKKYDGPE 233 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+K+ L NP Sbjct: 234 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPV 293 Query: 542 TRITI 556 R T+ Sbjct: 294 KRGTL 298
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 169 bits (428), Expect = 5e-42 Identities = 77/185 (41%), Positives = 119/185 (64%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME + GE+FD + S GR+KE +AR F+Q+++AV YCH + + H Sbjct: 120 KLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVH 179 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 180 RDLKAENLLLDAEANIKIADFG---FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + ++++ L NP Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPA 296 Query: 542 TRITI 556 R T+ Sbjct: 297 KRCTL 301
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 169 bits (428), Expect = 5e-42 Identities = 77/185 (41%), Positives = 119/185 (64%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME + GE+FD + S GR+KE +AR F+Q+++AV YCH + + H Sbjct: 120 KLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVH 179 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 180 RDLKAENLLLDAEANIKIADFG---FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPE 236 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + ++++ L NP Sbjct: 237 VDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPA 296 Query: 542 TRITI 556 R T+ Sbjct: 297 KRCTL 301
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 169 bits (427), Expect = 6e-42 Identities = 78/182 (42%), Positives = 119/182 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q+++AV YCH + + H Sbjct: 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH 180 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD + +K++DFG S + L T CG+P Y APE+ K YDG + Sbjct: 181 RDLKAENLLLDGDMNIKIADFG---FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 237 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK+L NP Sbjct: 238 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPI 297 Query: 542 TR 547 R Sbjct: 298 KR 299
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 169 bits (427), Expect = 6e-42 Identities = 82/185 (44%), Positives = 117/185 (63%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+VM ++ +YIV E GE+FD + S G L E +ARK F Q+++AV+YCHS + H Sbjct: 87 KLYQVMETKDMLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEYCHSHHIVH 146 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDAN +K++DFG + L T CG+P Y APEV K Y+G Sbjct: 147 RDLKTENLLLDANMNIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEGPH 203 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L +P Sbjct: 204 LDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPT 263 Query: 542 TRITI 556 RITI Sbjct: 264 KRITI 268
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 167 bits (424), Expect = 1e-41 Identities = 79/185 (42%), Positives = 121/185 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+VM +++ +Y+V E GE+FD +A+ GRL E +AR+ F Q+++AVDYCH R + H Sbjct: 81 KLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVH 140 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD N +K++DFG + LL T CG+P Y APEV + Y+G + Sbjct: 141 RDLKAENLLLDNNMNIKIADFGFGNF---FKSGELLATWCGSPPYAAPEVFEGQQYEGPQ 197 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+L+VL+ G LPF+ L L +++ + F P + S + LI+++L +P+ Sbjct: 198 LDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPS 257 Query: 542 TRITI 556 R+TI Sbjct: 258 KRLTI 262
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 166 bits (420), Expect = 4e-41 Identities = 79/185 (42%), Positives = 121/185 (65%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+VM +++ +Y+V E GE+FD +A+ GRL E +AR+ F Q+++AVDYCH R V H Sbjct: 81 KLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVH 140 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD N +K++DFG + LL T CG+P Y APEV + Y+G + Sbjct: 141 RDLKAENLLLDNNMNIKIADFGFGNF---FKTGELLATWCGSPPYAAPEVFEGQQYEGPQ 197 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+L+VL+ G LPF+ L L +++ + F P + S + LI+++L +P+ Sbjct: 198 LDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPS 257 Query: 542 TRITI 556 R++I Sbjct: 258 KRLSI 262
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 166 bits (419), Expect = 5e-41 Identities = 80/185 (43%), Positives = 117/185 (63%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+VM ++ +YIV E GE+FD + S G L E++ARK F Q+++AV+YCH + H Sbjct: 88 KLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVH 147 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD N +K++DFG + L T CG+P Y APEV K Y+G + Sbjct: 148 RDLKTENLLLDGNMDIKLADFGFGNF---YKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQ 204 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L +P Sbjct: 205 LDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPA 264 Query: 542 TRITI 556 RITI Sbjct: 265 RRITI 269
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 165 bits (418), Expect = 7e-41 Identities = 80/185 (43%), Positives = 118/185 (63%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+VM ++ +YIV E GE+FD + S G L E++ARK F Q+++AV+YCH+ + H Sbjct: 88 KLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHIVH 147 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD N +K++DFG + L T CG+P Y APEV K Y+G + Sbjct: 148 RDLKTENLLLDGNMDIKLADFGFGNF---YKPGEPLSTWCGSPPYAAPEVFEGKEYEGPQ 204 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L +P Sbjct: 205 LDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPA 264 Query: 542 TRITI 556 RITI Sbjct: 265 KRITI 269
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 165 bits (417), Expect = 9e-41 Identities = 78/185 (42%), Positives = 119/185 (64%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV+ + +Y+VME +GGE+FD + + GR+KE +AR F+Q++ V YCH + + H Sbjct: 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVLHVQYCHQKFIVH 173 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLDA+ +K++DFG S + L T CG+P Y APE+ K DG + Sbjct: 174 RDLKAENLLLDADMNIKIADFG---FSNEFTFGNKLDTFCGSPPYAAPELFQGKKIDGPE 230 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GVIL+ L++G LPF+ NL L +++ + + P + ST + L+KK L NP+ Sbjct: 231 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS 290 Query: 542 TRITI 556 R T+ Sbjct: 291 KRGTL 295
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 160 bits (406), Expect = 2e-39 Identities = 77/185 (41%), Positives = 120/185 (64%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+VM +++ +Y+V E GE+FD +A+ GRL E +AR+ F Q+++AVDYCH R + H Sbjct: 81 KLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVH 140 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD N +K++DF + + LL T G+P Y APEV + Y+G + Sbjct: 141 RDLKAENLLLDNNMNIKIADF---SFGNFFKSGELLATWRGSPPYAAPEVFEGQQYEGPQ 197 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+L+VL+ G LPF+ L L +++ + F P + S + LI+++L +P+ Sbjct: 198 LDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPS 257 Query: 542 TRITI 556 R+TI Sbjct: 258 KRLTI 262
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 160 bits (405), Expect = 2e-39 Identities = 78/185 (42%), Positives = 118/185 (63%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y+VM ++ +YIV E GE+FD + S G L E++AR+ F Q+++AV+YCH+ + H Sbjct: 88 KLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHIVH 147 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD+N +K++DFG + L T G+P Y APEV K Y+G + Sbjct: 148 RDLKTENLLLDSNMDIKLADFGFGNF---YKPGEPLSTCVGSPPYAAPEVFEGKEYEGPQ 204 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+L+VL+ G LPF+ NL L +++ + F P + S + LI+++L +P Sbjct: 205 LDVWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPA 264 Query: 542 TRITI 556 RITI Sbjct: 265 KRITI 269
>KPSH1_BRARE (Q501V0) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 422 Score = 160 bits (404), Expect = 3e-39 Identities = 84/191 (43%), Positives = 125/191 (65%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ EV + ++Y+VMEL TGGELFD+I +RG E DA + Q +++ V Y H+ G+ H Sbjct: 155 QLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGITH 214 Query: 182 RDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL A+ + ++DFGL A +++ ++ L+ TTCGTP Y+APE++ K Y Sbjct: 215 RDLKPENLLYYHPGADSKIMITDFGL-ASTRKKGDECLMKTTCGTPEYIAPEILVRKPYT 273 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTS--AKKLIKK 520 A D+W+ GVI ++L++G +PFED N M LY++I K FS W S S AK I + Sbjct: 274 NA-VDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDR 332 Query: 521 ILDPNPNTRIT 553 +L +PN R++ Sbjct: 333 VLTVDPNERLS 343
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 159 bits (403), Expect = 4e-39 Identities = 91/197 (46%), Positives = 118/197 (59%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME GGELF++I + GR ED+AR +FQQLI+ V YCHS V H Sbjct: 62 RFKEVVLTPTHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQVCH 121 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + T LK+ DFG S + +LH +T GTP Y+APEV++ K Sbjct: 122 RDLKLENTLLDGSVTPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLSRK 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTSA--K 505 YDG AD+WSCGV L+V++ G PFED N +I +S P + SA + Sbjct: 175 EYDGKVADVWSCGVTLYVMLVGAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRVSADCR 234 Query: 506 KLIKKILDPNPNTRITI 556 L+ +I NP RITI Sbjct: 235 HLLSRIFVGNPEQRITI 251
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 159 bits (402), Expect = 5e-39 Identities = 79/208 (37%), Positives = 122/208 (58%), Gaps = 23/208 (11%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQ--------------- 136 +++EV+ + +Y++ME +GGE+FD + + GR+KE +AR F+Q Sbjct: 117 KLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQVSFD 176 Query: 137 --------LINAVDYCHSRGVYHRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLH 292 +++AV YCH + + HRDLK ENLLLDA+ +K++DFG S + G L Sbjct: 177 LLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFS---NEFTVGGKLD 233 Query: 293 TTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADF 472 T CG+P Y APE+ K YDG + D+WS GVIL+ L++G LPF+ NL L +++ + + Sbjct: 234 TFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKY 293 Query: 473 SCPSWFSTSAKKLIKKILDPNPNTRITI 556 P + ST + L+K+ L NP R T+ Sbjct: 294 RIPFYMSTDCENLLKRFLVLNPIKRGTL 321
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 159 bits (402), Expect = 5e-39 Identities = 81/188 (43%), Positives = 119/188 (63%), Gaps = 4/188 (2%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 +Y+V + +Y+++E GELF+ + G L E +A F+Q+I + YCH+ G+ HR Sbjct: 92 LYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHR 151 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 DLKPENLLLD+ +K++DFG++AL + LL T+CG+P+Y APE+++ Y+G + Sbjct: 152 DLKPENLLLDSFYNIKIADFGMAALQ---TDADLLETSCGSPHYAAPEIVSGLPYEGFAS 208 Query: 365 DLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFSCP--SWFSTSAKKLIKKILDP 532 D+WSCGVILF L+ G LPF E+ N+ L K+ K F P + S A+ LI KIL Sbjct: 209 DVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVV 268 Query: 533 NPNTRITI 556 +P RI I Sbjct: 269 DPRQRIKI 276
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 157 bits (397), Expect = 2e-38 Identities = 91/197 (46%), Positives = 118/197 (59%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME +GGELF++I S GR ED+AR +FQQLI+ V YCHS V H Sbjct: 80 RFKEVILTPTHLAIVMEYASGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQVCH 139 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV+ K Sbjct: 140 RDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLLKK 192 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N +KI +S P + S + Sbjct: 193 EYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECR 252 Query: 506 KLIKKILDPNPNTRITI 556 LI +I NP +RIT+ Sbjct: 253 DLITRIFVGNPASRITM 269
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 157 bits (397), Expect = 2e-38 Identities = 85/189 (44%), Positives = 116/189 (61%), Gaps = 19/189 (10%) Frame = +2 Query: 41 IVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDAN 220 IV++ V GGELFD I +R RL++ A + F QLI+ V Y HSRGV HRDLK EN+LLD N Sbjct: 575 IVLDYVNGGELFDYILARRRLEDSVACRLFAQLISGVAYLHSRGVVHRDLKLENILLDTN 634 Query: 221 GTLKVSDFG----------LSALSQQVREDGLLHTTCGTPNYVAPEVINNKG--YDGAKA 364 + ++DFG LS S + L T+CG+P Y APE++N K Y G +A Sbjct: 635 RNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAGTQA 694 Query: 365 DLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSCPSWFSTSAKKLIKKI 523 D+WSCGVIL+ ++AGYLPF+D N+ LY+ I P +F + A+ ++KKI Sbjct: 695 DIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRLYRYICSTPLIFPEFFKSKARDILKKI 754 Query: 524 LDPNPNTRI 550 L P+P R+ Sbjct: 755 LVPDPAKRV 763
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 157 bits (396), Expect = 2e-38 Identities = 88/197 (44%), Positives = 119/197 (60%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV + T + IVME GGELF++I + GR ED+AR +FQQLI+ V YCHS + H Sbjct: 63 RFKEVCLTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEICH 122 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + T +K+ DFG S + LLH +T GTP Y+APEV++ K Sbjct: 123 RDLKLENTLLDGSPTPRVKICDFGYS-------KSALLHSKPKSTVGTPAYIAPEVLSRK 175 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N +I +S P + S+ + Sbjct: 176 EYDGKVADVWSCGVTLYVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSSDCR 235 Query: 506 KLIKKILDPNPNTRITI 556 +L+ +I +P+ RITI Sbjct: 236 RLLSQIFVADPSKRITI 252
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 156 bits (395), Expect = 3e-38 Identities = 88/197 (44%), Positives = 117/197 (59%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME GGELFD+I RGR ED+AR +FQQLI V YCH + H Sbjct: 62 RFKEVILTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHMQICH 121 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN+LLD + LK+ DFG S + +LH + GTP Y+APEV++ + Sbjct: 122 RDLKLENVLLDGSPAPRLKICDFGYS-------KSSVLHSRPKSAVGTPAYIAPEVLSRR 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTSA--K 505 YDG AD+WSCGV L+V++ G PFED N+ ++I + P + SA K Sbjct: 175 EYDGKLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAECK 234 Query: 506 KLIKKILDPNPNTRITI 556 +LI +I NP RIT+ Sbjct: 235 QLIARIFVNNPLRRITM 251
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 156 bits (395), Expect = 3e-38 Identities = 90/197 (45%), Positives = 118/197 (59%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME +GGELF++I + GR ED+AR +FQQLI+ V YCHS V H Sbjct: 81 RFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQVCH 140 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV+ K Sbjct: 141 RDLKLENTLLDGSTAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLLKK 193 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N ++I +S P + S + Sbjct: 194 EYDGKIADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPECR 253 Query: 506 KLIKKILDPNPNTRITI 556 LI +I NP TRI+I Sbjct: 254 DLIARIFVANPATRISI 270
>NUAK1_HUMAN (O60285) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| (AMPK-related protein kinase 5) Length = 661 Score = 156 bits (395), Expect = 3e-38 Identities = 79/184 (42%), Positives = 120/184 (65%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 +YEV ++ KI I+ME + GEL+D I+ R RL E + R +F+Q+++AV YCH GV HR Sbjct: 118 IYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHR 177 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 DLK EN+LLD N +K++DFGLS L Q +D L T CG+P Y +PE++N + Y G + Sbjct: 178 DLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRGPEV 234 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNT 544 D W+ GV+L+ L+ G +PF+ + L ++I ++ P+ + A+ LI+ +L NP+ Sbjct: 235 DSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDR 293 Query: 545 RITI 556 R TI Sbjct: 294 RATI 297
>NUAK1_MOUSE (Q641K5) NUAK family, SNF1-like kinase 1 (EC 2.7.11.1)| Length = 658 Score = 156 bits (395), Expect = 3e-38 Identities = 79/184 (42%), Positives = 120/184 (65%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 +YEV ++ KI I+ME + GEL+D I+ R RL E + R +F+Q+++AV YCH GV HR Sbjct: 119 IYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHR 178 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 DLK EN+LLD N +K++DFGLS L Q +D L T CG+P Y +PE++N + Y G + Sbjct: 179 DLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRGPEV 235 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNT 544 D W+ GV+L+ L+ G +PF+ + L ++I ++ P+ + A+ LI+ +L NP+ Sbjct: 236 DSWALGVLLYTLIYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLIRWMLMVNPDR 294 Query: 545 RITI 556 R TI Sbjct: 295 RATI 298
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 156 bits (394), Expect = 4e-38 Identities = 85/188 (45%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S T Y+VM+LV+GGELFD+I RG E DA QQ+++AV Y H G+ HRDL Sbjct: 85 DIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDL 144 Query: 191 KPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL + N + ++DFGLS + Q +G++ T CGTP YVAPEV+ K Y A Sbjct: 145 KPENLLYLTPEENSKIMITDFGLSKMEQ----NGIMSTACGTPGYVAPEVLAQKPYSKA- 199 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF + L++KI + +F P W S SAK I +L+ Sbjct: 200 VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLE 259 Query: 530 PNPNTRIT 553 +PN R T Sbjct: 260 KDPNERYT 267
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 155 bits (393), Expect = 6e-38 Identities = 85/188 (45%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S T Y+VM+LV+GGELFD+I RG E DA QQ+++AV Y H G+ HRDL Sbjct: 85 DIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDL 144 Query: 191 KPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL + N + ++DFGLS + Q +G++ T CGTP YVAPEV+ K Y A Sbjct: 145 KPENLLYLTPEENSKIMITDFGLSKMEQ----NGVMSTACGTPGYVAPEVLAQKPYSKA- 199 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF + L++KI + +F P W S SAK I +L+ Sbjct: 200 VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLE 259 Query: 530 PNPNTRIT 553 +PN R T Sbjct: 260 KDPNERYT 267
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 155 bits (393), Expect = 6e-38 Identities = 85/188 (45%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S T Y+VM+LV+GGELFD+I RG E DA QQ+++AV Y H G+ HRDL Sbjct: 85 DIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDL 144 Query: 191 KPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL + N + ++DFGLS + Q +G++ T CGTP YVAPEV+ K Y A Sbjct: 145 KPENLLYLTPEENSKIMITDFGLSKMEQ----NGVMSTACGTPGYVAPEVLAQKPYSKA- 199 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF + L++KI + +F P W S SAK I +L+ Sbjct: 200 VDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLE 259 Query: 530 PNPNTRIT 553 +PN R T Sbjct: 260 KDPNERYT 267
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 155 bits (392), Expect = 7e-38 Identities = 89/197 (45%), Positives = 114/197 (57%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME GGELF++I S GR ED+AR +FQQLI+ V YCHS + H Sbjct: 62 RFKEVVLTPTHLAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVSYCHSMQICH 121 Query: 182 RDLKPENLLLDAN--GTLKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV+ K Sbjct: 122 RDLKLENTLLDGSIAPRLKICDFGYS-------KSSLLHSQPKSTVGTPAYIAPEVLARK 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N +I + P + S + Sbjct: 175 EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRVSMECR 234 Query: 506 KLIKKILDPNPNTRITI 556 L+ +I NP RITI Sbjct: 235 HLLSRIFVANPEQRITI 251
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 154 bits (390), Expect = 1e-37 Identities = 83/191 (43%), Positives = 124/191 (64%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ EV ++ ++Y+VMEL TGGELFD+I ++G E DA + Q +++ V Y H+ G+ H Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITH 215 Query: 182 RDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL GT + ++DFGL A +++ +D L+ TTCGTP Y+APEV+ K Y Sbjct: 216 RDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYT 274 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSWFSTS--AKKLIKK 520 + D+W+ GVI ++L++G +PFED N LY++I K +S W S S AK I + Sbjct: 275 NS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDR 333 Query: 521 ILDPNPNTRIT 553 +L +P R+T Sbjct: 334 LLTVDPGARMT 344
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 154 bits (390), Expect = 1e-37 Identities = 80/190 (42%), Positives = 121/190 (63%), Gaps = 8/190 (4%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 EV+ + I IV+E V+GGE + I + RLKE A + F QLI+ V+Y H +G+ HRDL Sbjct: 117 EVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDL 176 Query: 191 KPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE-VINNKGYDGAKAD 367 K ENLLLD + L ++DFG +++ ++ L+ T+CG+P Y APE V++ K Y+ KAD Sbjct: 177 KLENLLLDKHENLVITDFGF--VNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKAD 234 Query: 368 LWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 +WSCGVIL+ ++AGYLP++D ++ LYK I + P + + + L+++IL Sbjct: 235 VWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRIL 294 Query: 527 DPNPNTRITI 556 PNP RI + Sbjct: 295 VPNPRRRINL 304
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 154 bits (389), Expect = 2e-37 Identities = 82/191 (42%), Positives = 124/191 (64%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ EV ++ ++Y+VMEL TGGELFD+I ++G E DA + Q +++ V Y H+ G+ H Sbjct: 156 QLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITH 215 Query: 182 RDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL GT + ++DFGL A +++ +D L+ TTCGTP Y+APEV+ K Y Sbjct: 216 RDLKPENLLYYHPGTDSKIIITDFGL-ASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYT 274 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSWFSTS--AKKLIKK 520 + D+W+ GVI ++L++G +PFED N LY++I + +S W S S AK I + Sbjct: 275 NS-VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDR 333 Query: 521 ILDPNPNTRIT 553 +L +P R+T Sbjct: 334 LLTVDPGARMT 344
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 154 bits (388), Expect = 2e-37 Identities = 87/197 (44%), Positives = 114/197 (57%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + I ME GGELF++I S GR ED+AR +FQQLI+ V YCH+ + H Sbjct: 62 RFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQICH 121 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ + Sbjct: 122 RDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPEVLSRR 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N +KI + P + S K Sbjct: 175 EYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCK 234 Query: 506 KLIKKILDPNPNTRITI 556 L+ +I N RITI Sbjct: 235 NLLSRIFVANSLKRITI 251
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 153 bits (387), Expect = 3e-37 Identities = 77/186 (41%), Positives = 115/186 (61%), Gaps = 1/186 (0%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y+V +Y+ +E V GELF I G L E +A Y Q+++AV +CH H Sbjct: 67 RLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRFRH 126 Query: 182 RDLKPENLLLDANGT-LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGA 358 RDLK EN+L+ N +K++DFG++ + D L CG+ +Y+APE++++K Y GA Sbjct: 127 RDLKLENILIKVNEQQIKIADFGMATVEPN---DSCLENYCGSLHYLAPEIVSHKPYRGA 183 Query: 359 KADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 538 AD+WSCGVIL+ L++ LPF N +Y KI + PS S++A+ L+ ++LD NP Sbjct: 184 PADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHGAYDLPSSISSAAQDLLHRMLDVNP 243 Query: 539 NTRITI 556 +TRITI Sbjct: 244 STRITI 249
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 153 bits (387), Expect = 3e-37 Identities = 87/197 (44%), Positives = 114/197 (57%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME GGELFD+I + GR ED+AR +FQQLI V YCH + H Sbjct: 62 RFKEVVVTPTHLAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFMQICH 121 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ + Sbjct: 122 RDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPEVLSRR 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N +I + P + S + Sbjct: 175 EYDGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQDCR 234 Query: 506 KLIKKILDPNPNTRITI 556 +L+ +I NP RITI Sbjct: 235 QLLSRIFVANPAKRITI 251
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 153 bits (387), Expect = 3e-37 Identities = 87/197 (44%), Positives = 114/197 (57%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME GGELFD+I S GR ED++R +FQQLI V YCH + H Sbjct: 62 RFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFMQICH 121 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ + Sbjct: 122 RDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSKPKSTVGTPAYIAPEVLSRR 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N +I + P + S + Sbjct: 175 EYDGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHISQDCR 234 Query: 506 KLIKKILDPNPNTRITI 556 +L+ +I NP RITI Sbjct: 235 QLLSRIFVANPAKRITI 251
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 153 bits (386), Expect = 4e-37 Identities = 83/188 (44%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S +Y++M+LV+GGELFD+I +G E DA + Q+++AV Y H G+ HRDL Sbjct: 83 DIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDL 142 Query: 191 KPENLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL LD + + +SDFGLS + +L T CGTP YVAPEV+ K Y A Sbjct: 143 KPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKPYSKA- 198 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I+ +++ Sbjct: 199 VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLME 258 Query: 530 PNPNTRIT 553 +P R T Sbjct: 259 KDPEKRFT 266
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 153 bits (386), Expect = 4e-37 Identities = 83/188 (44%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S +Y++M+LV+GGELFD+I +G E DA + Q+++AV Y H G+ HRDL Sbjct: 83 DIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDL 142 Query: 191 KPENLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL LD + + +SDFGLS + +L T CGTP YVAPEV+ K Y A Sbjct: 143 KPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKPYSKA- 198 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I+ +++ Sbjct: 199 VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLME 258 Query: 530 PNPNTRIT 553 +P R T Sbjct: 259 KDPEKRFT 266
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 153 bits (386), Expect = 4e-37 Identities = 83/188 (44%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S +Y++M+LV+GGELFD+I +G E DA + Q+++AV Y H G+ HRDL Sbjct: 83 DIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDL 142 Query: 191 KPENLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL LD + + +SDFGLS + +L T CGTP YVAPEV+ K Y A Sbjct: 143 KPENLLYYSLDEDSKIMISDFGLSKMED---PGSVLSTACGTPGYVAPEVLAQKPYSKA- 198 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I+ +++ Sbjct: 199 VDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLME 258 Query: 530 PNPNTRIT 553 +P R T Sbjct: 259 KDPEKRFT 266
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 153 bits (386), Expect = 4e-37 Identities = 83/188 (44%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S +Y+VM+LV+GGELFD+I +G E DA +Q+++AV Y H G+ HRDL Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145 Query: 191 KPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL D + +SDFGLS + + ++ T CGTP YVAPEV+ K Y A Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSKME---GKGDVMSTACGTPGYVAPEVLAQKPYSKA- 201 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I+ +++ Sbjct: 202 VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLME 261 Query: 530 PNPNTRIT 553 +PN R T Sbjct: 262 KDPNKRYT 269
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 153 bits (386), Expect = 4e-37 Identities = 83/188 (44%), Positives = 115/188 (61%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 ++ S +Y+VM+LV+GGELFD+I +G E DA +Q+++AV Y H G+ HRDL Sbjct: 86 DIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDL 145 Query: 191 KPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL D + +SDFGLS + + ++ T CGTP YVAPEV+ K Y A Sbjct: 146 KPENLLYYSQDEESKIMISDFGLSKME---GKGDVMSTACGTPGYVAPEVLAQKPYSKA- 201 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D WS GVI ++L+ GY PF D N L+++I KA +F P W S SAK I+ +++ Sbjct: 202 VDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLME 261 Query: 530 PNPNTRIT 553 +PN R T Sbjct: 262 KDPNKRYT 269
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 152 bits (383), Expect = 8e-37 Identities = 86/197 (43%), Positives = 115/197 (58%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME +GGELFD+I + GR E +AR +FQQLI VDYCHS + H Sbjct: 62 RFKEVILTPTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQICH 121 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV++ + Sbjct: 122 RDLKLENTLLDGSPAPLLKICDFGYS-------KSSILHSRPKSTVGTPAYIAPEVLSRR 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSW--FSTSAK 505 YDG AD+WSCGV L+V++ G PFED N ++I + P + S K Sbjct: 175 EYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECK 234 Query: 506 KLIKKILDPNPNTRITI 556 L+ +I N RIT+ Sbjct: 235 HLLSRIFVTNSAKRITL 251
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 152 bits (383), Expect = 8e-37 Identities = 75/182 (41%), Positives = 113/182 (62%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 +V + + Y+V E V GG++ D I S G+LKE ARK+ +Q+ +A+ Y H V HRDL Sbjct: 208 DVYITNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQNSVVHRDL 267 Query: 191 KPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADL 370 K EN+L+ G +K+ DFGLS L R L T CG+ + APE++N + Y G + D+ Sbjct: 268 KIENILISKTGDIKIIDFGLSNL---YRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDV 324 Query: 371 WSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 WS G++L+VL+ G +PF+D N+ AL+ KI K PS+ S+ K L+ ++L +P R Sbjct: 325 WSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYPSYLSSDCKGLLSRMLVTDPLKRA 384 Query: 551 TI 556 T+ Sbjct: 385 TL 386
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 151 bits (382), Expect = 1e-36 Identities = 87/197 (44%), Positives = 114/197 (57%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME +GGELF +I + GR ED+ R +FQQLI+ V YCHS V H Sbjct: 52 RFKEVVLTPTHLAIVMEYASGGELFQRICNAGRFSEDEGRFFFQQLISGVSYCHSMQVCH 111 Query: 182 RDLKPENLLLDAN--GTLKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV++ + Sbjct: 112 RDLKLENTLLDGSVAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLSRR 164 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTSAK-- 505 YDG AD+WSCGV L+V++ G PFED N +I +S P + S Sbjct: 165 EYDGKVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCI 224 Query: 506 KLIKKILDPNPNTRITI 556 L+ +I NP RITI Sbjct: 225 HLLSRIFVGNPQQRITI 241
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 151 bits (381), Expect = 1e-36 Identities = 84/188 (44%), Positives = 114/188 (60%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 +V S + +Y+ MELVTGGELFD+I RG E DA Q++ AV Y HS G+ HRDL Sbjct: 78 DVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDL 137 Query: 191 KPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL + + VSDFGLS +++ +L T CGTP YVAPE++ K Y G Sbjct: 138 KPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKPY-GKA 192 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D+W+ GVI ++L+ GY PF D + L+ +I +A +F P W S SAK I+ +L+ Sbjct: 193 VDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLE 252 Query: 530 PNPNTRIT 553 +P R T Sbjct: 253 RDPQKRFT 260
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 151 bits (381), Expect = 1e-36 Identities = 84/188 (44%), Positives = 114/188 (60%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 +V S + +Y+ MELVTGGELFD+I RG E DA Q++ AV Y HS G+ HRDL Sbjct: 78 DVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDL 137 Query: 191 KPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL + + VSDFGLS +++ +L T CGTP YVAPE++ K Y G Sbjct: 138 KPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKPY-GKA 192 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D+W+ GVI ++L+ GY PF D + L+ +I +A +F P W S SAK I+ +L+ Sbjct: 193 VDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLE 252 Query: 530 PNPNTRIT 553 +P R T Sbjct: 253 RDPQKRFT 260
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 151 bits (381), Expect = 1e-36 Identities = 84/188 (44%), Positives = 114/188 (60%), Gaps = 7/188 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 +V S + +Y+ MELVTGGELFD+I RG E DA Q++ AV Y HS G+ HRDL Sbjct: 78 DVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDL 137 Query: 191 KPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLL + + VSDFGLS +++ +L T CGTP YVAPE++ K Y G Sbjct: 138 KPENLLYATPFEDSKIMVSDFGLS----KIQAGNMLGTACGTPGYVAPELLEQKPY-GKA 192 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILD 529 D+W+ GVI ++L+ GY PF D + L+ +I +A +F P W S SAK I+ +L+ Sbjct: 193 VDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLE 252 Query: 530 PNPNTRIT 553 +P R T Sbjct: 253 RDPQKRFT 260
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 150 bits (380), Expect = 2e-36 Identities = 88/197 (44%), Positives = 115/197 (58%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + T + IVME +GGELF++I R ED+AR +FQQLI+ V YCHS V H Sbjct: 91 RFKEVILTPTHLAIVMEYASGGELFERICKNVRFSEDEARYFFQQLISGVSYCHSMQVCH 150 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + +LH +T GTP Y+APEV+ K Sbjct: 151 RDLKLENTLLDGSPAPRLKICDFGYS-------KSSVLHSQPKSTVGTPAYIAPEVLLKK 203 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPS--WFSTSAK 505 YDG AD+WSCGV L+V++ G PFED N ++I +S P S + Sbjct: 204 EYDGKTADVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTIQRILNVQYSIPENVDISPECR 263 Query: 506 KLIKKILDPNPNTRITI 556 LI +I +P+ RITI Sbjct: 264 HLISRIFVGDPSLRITI 280
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 149 bits (377), Expect = 4e-36 Identities = 80/191 (41%), Positives = 117/191 (61%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ EV ++ K+Y+VMEL TGGELFD+I ++G E DA + +++ V Y H G+ H Sbjct: 137 QLIEVFETKDKVYMVMELATGGELFDRIIAKGSFTERDATRVLNMVLDGVKYLHGLGITH 196 Query: 182 RDLKPENLLLDANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL G + ++DFGLS S + + + TTCGTP Y+APE+I K Y Sbjct: 197 RDLKPENLLYYHPGHDSKIMITDFGLS--STRKGPENFMRTTCGTPEYIAPEIIARKPY- 253 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPS--W--FSTSAKKLIKK 520 + D+W+ GVI ++L++G +PF+D N LY+ I KA +S W S AK I K Sbjct: 254 MCQVDMWAVGVITYILLSGTMPFDDENKTRLYRLILKAKYSYAGEHWKDVSAQAKDFIDK 313 Query: 521 ILDPNPNTRIT 553 +L +P R++ Sbjct: 314 LLVVSPGDRLS 324
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 147 bits (372), Expect = 2e-35 Identities = 83/191 (43%), Positives = 118/191 (61%), Gaps = 6/191 (3%) Frame = +2 Query: 2 RMYEVMA-SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVY 178 + YE+ A S K+YIVMEL G+L + I +RG L+EDDARK F QL +A+ YCH V Sbjct: 74 KTYEIFATSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLDVV 133 Query: 179 HRDLKPENLLLDANGTLKVSDFGLSALSQQVREDG----LLHTTCGTPNYVAPEVINNKG 346 HRDLK ENLLLD + +K+SDFG S + +R+D L T CG+ Y APEV+ Sbjct: 134 HRDLKSENLLLDKDFNIKLSDFGFS--KRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIP 191 Query: 347 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMAL-YKKIYKADFSCPSWFSTSAKKLIKKI 523 Y D+WS GVIL++++ G +P++DSN+ L +K ++ +F + K LI ++ Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKLRIQKEHRVNFPRSKHLTGECKDLIYRM 251 Query: 524 LDPNPNTRITI 556 L P+ N R+ I Sbjct: 252 LQPDVNRRLHI 262
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 147 bits (370), Expect = 3e-35 Identities = 84/194 (43%), Positives = 120/194 (61%), Gaps = 9/194 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 RM++++ +Y+V+E + GG+L ++I S L ED ++ YF Q+ +AV Y H RG+ H Sbjct: 242 RMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITH 301 Query: 182 RDLKPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKP+N+LL+ N LKVSDFGLS V++D ++ T CGTP YVAPEV+ G + Sbjct: 302 RDLKPDNVLLETNDEETLLKVSDFGLSKF---VQKDSVMRTLCGTPLYVAPEVLITGGRE 358 Query: 353 G--AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSWFSTS--AKKLI 514 K D+WS GV+LF ++G LPF D ++I K F+ PSW S S AK LI Sbjct: 359 AYTKKVDIWSLGVVLFTCLSGTLPFSDEYGTPAAQQIKKGRFAYGHPSWKSVSQRAKLLI 418 Query: 515 KKILDPNPNTRITI 556 ++L +P R +I Sbjct: 419 NQMLIVDPERRPSI 432
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 147 bits (370), Expect = 3e-35 Identities = 82/197 (41%), Positives = 112/197 (56%), Gaps = 12/197 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R EV+ + + IVME GGELF++I GR ED+AR +FQQL+ V YCH+ + H Sbjct: 62 RFKEVVVTGRHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVSYCHAMQICH 121 Query: 182 RDLKPENLLLDANGT--LKVSDFGLSALSQQVREDGLLH----TTCGTPNYVAPEVINNK 343 RDLK EN LLD + LK+ DFG S + LLH +T GTP Y+APEV++ + Sbjct: 122 RDLKLENTLLDGSPAPRLKICDFGYS-------KSSLLHSRPKSTVGTPAYIAPEVLSRR 174 Query: 344 GYDGAKADLWSCGVILFVLMAGYLPFED----SNLMALYKKIYKADFSCPSWFSTS--AK 505 YDG AD+WSCGV L+V++ G PFED N +I + P + S + Sbjct: 175 EYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHVSQPCR 234 Query: 506 KLIKKILDPNPNTRITI 556 L+ +I NP RI++ Sbjct: 235 HLLSRIFVANPYKRISM 251
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 145 bits (366), Expect = 7e-35 Identities = 79/192 (41%), Positives = 117/192 (60%), Gaps = 8/192 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ E+ + T+I +V+ELVTGGELFD+I +G E DAR +Q++ AV Y H G+ H Sbjct: 99 KLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHENGIVH 158 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL + LK++DFGLS + V L+ T CGTP Y APE++ Y Sbjct: 159 RDLKPENLLYATPAPDAPLKIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRGCAY- 214 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDS-NLMALYKKIYKAD--FSCPSW--FSTSAKKLIK 517 G + D+WS G+I ++L+ G+ PF D ++++I + F P W S +AK L+K Sbjct: 215 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVK 274 Query: 518 KILDPNPNTRIT 553 K++ +P R+T Sbjct: 275 KLIVLDPKKRLT 286
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 144 bits (364), Expect = 1e-34 Identities = 75/187 (40%), Positives = 115/187 (61%), Gaps = 2/187 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRGVY 178 R+YEV+ ++TK+Y+++EL GG++FD I L ED A+KYF Q+++A+ YCH V Sbjct: 77 RLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVV 136 Query: 179 HRDLKPENLLL-DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 355 HRDLKPEN++ + G +K++DFG S Q ++ L T+CG+ Y APE++ YD Sbjct: 137 HRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDA 193 Query: 356 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 535 D+WS GVILF+L+ G PF+++N I ++ PS S K LI ++L + Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 253 Query: 536 PNTRITI 556 P R ++ Sbjct: 254 PKRRASL 260
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 144 bits (364), Expect = 1e-34 Identities = 78/187 (41%), Positives = 116/187 (62%), Gaps = 7/187 (3%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 E+ + K+Y+VMELVTGGELFDKI +G E DA +++++AV Y H + HRDL Sbjct: 72 ELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNIVHRDL 131 Query: 191 KPENLLLDANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 KPENLLL + + ++DFGLS + Q ++ T CGTP+YVAPEV+N GYD + Sbjct: 132 KPENLLLKSKENHLEVAIADFGLSKIIGQTL---VMQTACGTPSYVAPEVLNATGYD-KE 187 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPS--W--FSTSAKKLIKKILD 529 D+WS GVI ++L+ G+ PF + ++++I +A++ P W S AK I K+L Sbjct: 188 VDMWSIGVITYILLCGFPPFYGDTVPEIFEQIMEANYEFPEEYWGGISKEAKDFIGKLLV 247 Query: 530 PNPNTRI 550 + + R+ Sbjct: 248 VDVSKRL 254
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 144 bits (363), Expect = 2e-34 Identities = 76/176 (43%), Positives = 109/176 (61%), Gaps = 3/176 (1%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA 217 Y+ +E GGELFD+I + E DA+K+FQQLI V+Y HS G+ HRD+KPENLLLD Sbjct: 81 YLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEYLHSIGITHRDIKPENLLLDE 140 Query: 218 NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFV 397 LK+SDFGL+ + + ++ LL+ CGT YVAPE+I ++ + D+WSCG++L Sbjct: 141 RDQLKISDFGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFHADPVDVWSCGIVLTA 200 Query: 398 LMAGYLPFEDSN-LMALYKKIYKADFSCPSWFSTSAK--KLIKKILDPNPNTRITI 556 ++AG LP++ N + Y + + W SA L+ K+L NP +RITI Sbjct: 201 MLAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLALLCKMLTENPQSRITI 256
>HUNK_PANTR (Q68UT7) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) Length = 714 Score = 144 bits (363), Expect = 2e-34 Identities = 77/188 (40%), Positives = 116/188 (61%), Gaps = 3/188 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ +++ + Y+VMEL GG L KI + RL+E +AR+Y +QLI+AV++ H GV H Sbjct: 125 QLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVH 184 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD + +K+ DFGLS + + T CG+P Y APE++ K Y G K Sbjct: 185 RDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPK 243 Query: 362 ADLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFS-CPSWFSTSAKKLIKKILDP 532 D+WS GV ++ ++ G LPF E +L ALY+K+ + + P+ ST A ++ +L+P Sbjct: 244 IDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEP 303 Query: 533 NPNTRITI 556 +P R I Sbjct: 304 DPVKRPNI 311
>HUNK_HUMAN (P57058) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19) Length = 714 Score = 144 bits (363), Expect = 2e-34 Identities = 77/188 (40%), Positives = 116/188 (61%), Gaps = 3/188 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ +++ + Y+VMEL GG L KI + RL+E +AR+Y +QLI+AV++ H GV H Sbjct: 125 QLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVH 184 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD + +K+ DFGLS + + T CG+P Y APE++ K Y G K Sbjct: 185 RDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPK 243 Query: 362 ADLWSCGVILFVLMAGYLPF--EDSNLMALYKKIYKADFS-CPSWFSTSAKKLIKKILDP 532 D+WS GV ++ ++ G LPF E +L ALY+K+ + + P+ ST A ++ +L+P Sbjct: 244 IDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEP 303 Query: 533 NPNTRITI 556 +P R I Sbjct: 304 DPVKRPNI 311
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 144 bits (362), Expect = 2e-34 Identities = 78/193 (40%), Positives = 118/193 (61%), Gaps = 8/193 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ EV+ + I IV+E GGE + I + RLKE +A + F QLI+ V Y HS+G+ H Sbjct: 114 KLEEVLQNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLISGVHYIHSKGLVH 173 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPE-VINNKGYDGA 358 RDLK ENLLLD N L ++DFG +++ + L+ T+CG+P Y APE VI+ + Y+ Sbjct: 174 RDLKLENLLLDKNENLVITDFGF--VNEFCSRNELMKTSCGSPCYAAPELVISAEPYEAR 231 Query: 359 KADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSCPSWFSTSAKKLIK 517 KAD+WSCGVIL+ ++AGYLP++D S++ LY I P + + L++ Sbjct: 232 KADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDYILPIPRDLLR 291 Query: 518 KILDPNPNTRITI 556 ++L +P RI + Sbjct: 292 RMLVSDPKKRINL 304
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 144 bits (362), Expect = 2e-34 Identities = 72/185 (38%), Positives = 108/185 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +++Y++++ GGELF ++ R + + Y +QL A+ YCHS+ V H Sbjct: 202 RLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKVIH 261 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL +NG LK++DFG S + R T CGT +Y+ PE+I + +D K Sbjct: 262 RDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD-EK 316 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLWS GV+ + + G PFE Y++I K +F P + S AK L+ K+L NPN Sbjct: 317 VDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEAKDLVSKLLKHNPN 376 Query: 542 TRITI 556 R+ + Sbjct: 377 HRLPL 381
>HUNK_MOUSE (O88866) Hormonally up-regulated neu tumor-associated kinase (EC| 2.7.11.1) (Serine/threonine-protein kinase MAK-V) Length = 714 Score = 143 bits (361), Expect = 3e-34 Identities = 79/188 (42%), Positives = 115/188 (61%), Gaps = 3/188 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ +++ + Y+VMEL GG L KI + RL E +AR+Y +QLI+AV++ H GV H Sbjct: 125 QLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVH 184 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK ENLLLD + +K+ DFGLS + + T CG+P Y APE++ K Y G K Sbjct: 185 RDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY-GPK 243 Query: 362 ADLWSCGVILFVLMAGYLPF--EDSNLMALYKK-IYKADFSCPSWFSTSAKKLIKKILDP 532 D+WS GV ++ ++ G LPF E +L ALY+K + KA P+ ST A ++ +L+P Sbjct: 244 IDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEP 303 Query: 533 NPNTRITI 556 +P R I Sbjct: 304 DPVKRPNI 311
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 143 bits (360), Expect = 4e-34 Identities = 78/192 (40%), Positives = 116/192 (60%), Gaps = 8/192 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ E+ + T+I +V+ELVTGGELFD+I +G E DA +Q++ AV Y H G+ H Sbjct: 99 KLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVH 158 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL + LK++DFGLS + V L+ T CGTP Y APE++ Y Sbjct: 159 RDLKPENLLYATPAPDAPLKIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRGCAY- 214 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDS-NLMALYKKIYKAD--FSCPSW--FSTSAKKLIK 517 G + D+WS G+I ++L+ G+ PF D ++++I + F P W S +AK L+K Sbjct: 215 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVK 274 Query: 518 KILDPNPNTRIT 553 K++ +P R+T Sbjct: 275 KLIVLDPKKRLT 286
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 142 bits (359), Expect = 5e-34 Identities = 85/194 (43%), Positives = 117/194 (60%), Gaps = 10/194 (5%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV H Sbjct: 74 RLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVH 133 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLS--ALSQQVREDGLLHTTCGTPNYVAPEVINNKG 346 RDLKPENLLL + +K++DFGL+ +Q R G GTP Y++PEV+ Sbjct: 134 RDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQRWFGF----AGTPGYLSPEVLRKDP 189 Query: 347 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA---DFSCPSW--FSTSAKKL 511 Y G DLW+CGVIL++L+ GY PF D + LY++I KA DF P W + AK L Sbjct: 190 Y-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQI-KARAYDFPSPEWDTVTPEAKDL 247 Query: 512 IKKILDPNPNTRIT 553 I K+L NP+ RIT Sbjct: 248 INKMLTINPSKRIT 261
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 142 bits (358), Expect = 6e-34 Identities = 79/191 (41%), Positives = 113/191 (59%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ + Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH GV H Sbjct: 75 RLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVH 134 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Y Sbjct: 135 RDLKPENLLLASKAKGAAVKLADFGLAIEVQ--GDHQAWFGFAGTPGYLSPEVLKKEPY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY +I D+ P W + AK LI + Sbjct: 192 GKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQ 251 Query: 521 ILDPNPNTRIT 553 +L NPN RIT Sbjct: 252 MLTVNPNKRIT 262
>CHK1_USTMA (P0C198) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 662 Score = 142 bits (358), Expect = 6e-34 Identities = 75/177 (42%), Positives = 109/177 (61%), Gaps = 4/177 (2%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD 214 +Y+V+EL GG+LFDKIA ++ED A YFQQL+ ++Y HS+GV HRD+KPEN+LLD Sbjct: 143 LYMVLELGAGGDLFDKIAPDYGVEEDLAHFYFQQLLAGLEYIHSQGVTHRDIKPENMLLD 202 Query: 215 ANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILF 394 A G LK++DFGL ++ + ++ L CG+ Y+APE +N K Y G D+WS GV+LF Sbjct: 203 AEGNLKIADFGLCSVYKYKGKERELTGACGSLPYIAPE-MNGKPYRGEPVDVWSSGVVLF 261 Query: 395 VLMAGYLPFEDSNLMALYKKIYKAD--FSCPSW--FSTSAKKLIKKILDPNPNTRIT 553 ++ G P+++ + Y+ F W A L+KK++ P P RIT Sbjct: 262 AMLVGSTPWDEPTSRSPEYSAYRTGKLFEYDPWPRIPQDALSLLKKMMHPTPEKRIT 318
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 142 bits (358), Expect = 6e-34 Identities = 81/191 (42%), Positives = 113/191 (59%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV H Sbjct: 74 RLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVH 133 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ + E GTP Y++PEV+ Y Sbjct: 134 RDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 190 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G DLW+CGVIL++L+ GY PF D + LY++I DF P W + AK LI K Sbjct: 191 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 250 Query: 521 ILDPNPNTRIT 553 +L NP+ RIT Sbjct: 251 MLTINPSKRIT 261
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 142 bits (358), Expect = 6e-34 Identities = 81/191 (42%), Positives = 113/191 (59%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV H Sbjct: 74 RLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVH 133 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ + E GTP Y++PEV+ Y Sbjct: 134 RDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 190 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G DLW+CGVIL++L+ GY PF D + LY++I DF P W + AK LI K Sbjct: 191 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 250 Query: 521 ILDPNPNTRIT 553 +L NP+ RIT Sbjct: 251 MLTINPSKRIT 261
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 142 bits (358), Expect = 6e-34 Identities = 81/191 (42%), Positives = 113/191 (59%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y++ +LVTGGELF+ I +R E DA QQ++ AV +CH GV H Sbjct: 74 RLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVH 133 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ + E GTP Y++PEV+ Y Sbjct: 134 RDLKPENLLLASKLKGAAVKLADFGLAI--EVEGEQQAWFGFAGTPGYLSPEVLRKDPY- 190 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G DLW+CGVIL++L+ GY PF D + LY++I DF P W + AK LI K Sbjct: 191 GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 250 Query: 521 ILDPNPNTRIT 553 +L NP+ RIT Sbjct: 251 MLTINPSKRIT 261
>DCAK1_MOUSE (Q9JLM8) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 756 Score = 142 bits (357), Expect = 8e-34 Identities = 83/193 (43%), Positives = 115/193 (59%), Gaps = 10/193 (5%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 + E M T++Y+VMELV GG+LFD I S + E DA L +A+ Y HS + HR Sbjct: 467 LIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHR 526 Query: 185 DLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 D+KPENLL+ D + +LK+ DFGL+ + DG L+T CGTP YVAPE+I GY Sbjct: 527 DIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEIIAETGY- 580 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDS--NLMALYKKIY--KADFSCPSW--FSTSAKKLI 514 G K D+W+ GVI ++L+ G+ PF S + L+ +I + DF P W S SAK+LI Sbjct: 581 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 640 Query: 515 KKILDPNPNTRIT 553 +L N + R + Sbjct: 641 NMMLLVNVDQRFS 653
>DCAK1_RAT (O08875) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) (Calcium/calmodulin-dependent protein kinase type I-like CPG16) Length = 433 Score = 142 bits (357), Expect = 8e-34 Identities = 83/193 (43%), Positives = 115/193 (59%), Gaps = 10/193 (5%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 + E M T++Y+VMELV GG+LFD I S + E DA L +A+ Y HS + HR Sbjct: 144 LIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHR 203 Query: 185 DLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 D+KPENLL+ D + +LK+ DFGL+ + DG L+T CGTP YVAPE+I GY Sbjct: 204 DIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEIIAETGY- 257 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDS--NLMALYKKIY--KADFSCPSW--FSTSAKKLI 514 G K D+W+ GVI ++L+ G+ PF S + L+ +I + DF P W S SAK+LI Sbjct: 258 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 317 Query: 515 KKILDPNPNTRIT 553 +L N + R + Sbjct: 318 NMMLLVNVDQRFS 330
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 142 bits (357), Expect = 8e-34 Identities = 80/192 (41%), Positives = 114/192 (59%), Gaps = 7/192 (3%) Frame = +2 Query: 2 RMYEVM-ASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVY 178 + YE+ S K+YIVMEL G+L + I +RG L ED+ARK F QL A+ YCH V Sbjct: 74 KTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVV 133 Query: 179 HRDLKPENLLLDANGTLKVSDFGLSALSQQVRED----GLLHTTCGTPNYVAPEVINNKG 346 HRDLK +NLLLD + +K+SDF S + +R+D L T CG+P Y APEV+ Sbjct: 134 HRDLKCDNLLLDKDFNIKLSDFSFS--KRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191 Query: 347 YDGAKADLWSCGVILFVLMAGYLPFEDSNL--MALYKKIYKADFSCPSWFSTSAKKLIKK 520 Y D+WS GVIL++++ G +P++DSN+ M +K ++ +F + K LI Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYH 251 Query: 521 ILDPNPNTRITI 556 +L P+ N R+ I Sbjct: 252 MLQPDVNRRLHI 263
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 142 bits (357), Expect = 8e-34 Identities = 77/192 (40%), Positives = 116/192 (60%), Gaps = 8/192 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ E+ + T+I +V+ELVTGGELFD+I +G E DA +Q++ AV Y H G+ H Sbjct: 103 KLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVH 162 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL + LK++DFGLS + V L+ T CGTP Y APE++ Y Sbjct: 163 RDLKPENLLYATPAPDAPLKIADFGLSKI---VEHQVLMKTVCGTPGYCAPEILRGCAY- 218 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDS-NLMALYKKIYKAD--FSCPSW--FSTSAKKLIK 517 G + D+WS G+I ++L+ G+ PF D ++++I + F P W S +AK L++ Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278 Query: 518 KILDPNPNTRIT 553 K++ +P R+T Sbjct: 279 KLIVLDPKKRLT 290
>DCAK2_MOUSE (Q6PGN3) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 756 Score = 141 bits (356), Expect = 1e-33 Identities = 81/193 (41%), Positives = 113/193 (58%), Gaps = 10/193 (5%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 + E M + T +++VMELV GG+LFD I S + E D L NA+ Y HS + HR Sbjct: 454 LVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHR 513 Query: 185 DLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 D+KPENLL+ D +LK+ DFGL+ + +G L+T CGTP YVAPE+I GY Sbjct: 514 DIKPENLLVCEYPDGTKSLKLGDFGLATV-----VEGPLYTVCGTPTYVAPEIIAETGY- 567 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMA--LYKKIY--KADFSCPSW--FSTSAKKLI 514 G K D+W+ GVI ++L+ G+ PF N + L+ +I K +F P W + SAK+LI Sbjct: 568 GLKVDVWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELI 627 Query: 515 KKILDPNPNTRIT 553 ++L N R T Sbjct: 628 SQMLQVNVEARCT 640
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 141 bits (356), Expect = 1e-33 Identities = 73/187 (39%), Positives = 114/187 (60%), Gaps = 2/187 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRGVY 178 R+YEV+ ++TK+Y+++EL GG++FD I L ED A+KYF Q+++A+ YCH V Sbjct: 77 RLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVV 136 Query: 179 HRDLKPENLLL-DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 355 HRDLKPEN++ + G +K++DFG S Q ++ L T+CG+ Y APE++ YD Sbjct: 137 HRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDA 193 Query: 356 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 535 D+WS GVILF+L+ G PF+++N I ++ P S + LI ++L + Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQRD 253 Query: 536 PNTRITI 556 P R ++ Sbjct: 254 PKRRASL 260
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 141 bits (356), Expect = 1e-33 Identities = 73/187 (39%), Positives = 114/187 (60%), Gaps = 2/187 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGR-LKEDDARKYFQQLINAVDYCHSRGVY 178 R+YEV+ ++TK+Y+++EL GG++FD I L ED A+KYF Q+++A+ YCH V Sbjct: 77 RLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVV 136 Query: 179 HRDLKPENLLL-DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 355 HRDLKPEN++ + G +K++DFG S Q ++ L T+CG+ Y APE++ YD Sbjct: 137 HRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKK---LTTSCGSLAYSAPEILLGDEYDA 193 Query: 356 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 535 D+WS GVILF+L+ G PF+++N I ++ P S + LI ++L + Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQRD 253 Query: 536 PNTRITI 556 P R ++ Sbjct: 254 PKRRASL 260
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 141 bits (356), Expect = 1e-33 Identities = 67/183 (36%), Positives = 111/183 (60%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 RM+ +I+++M+ + GGELF + R A+ Y ++ A++Y HS+ + + Sbjct: 149 RMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIY 208 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD NG +K++DFG + V +T CGTP+Y+APEV++ K Y+ Sbjct: 209 RDLKPENILLDKNGHIKITDFGFAKYVPDV-----TYTLCGTPDYIAPEVVSTKPYN-KS 262 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D WS G++++ ++AGY PF DSN M Y+KI A+ P +F+ K L+ +++ + + Sbjct: 263 IDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLS 322 Query: 542 TRI 550 R+ Sbjct: 323 QRL 325
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 141 bits (355), Expect = 1e-33 Identities = 68/183 (37%), Positives = 111/183 (60%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 RM+ ++++VM+ + GGELF + R A+ Y ++ A++Y HS+ + + Sbjct: 150 RMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIY 209 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD NG +K++DFG + V +T CGTP+Y+APEV++ K Y+ Sbjct: 210 RDLKPENILLDKNGHIKITDFGFAKYVPDV-----TYTLCGTPDYIAPEVVSTKPYN-KS 263 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D WS GV+++ ++AGY PF +SN M Y+ I A+ P +F A+ L+KK++ + + Sbjct: 264 VDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLS 323 Query: 542 TRI 550 R+ Sbjct: 324 ERL 326
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 141 bits (355), Expect = 1e-33 Identities = 67/185 (36%), Positives = 112/185 (60%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++E+ Y++ E V+GG+L D I G LKE ARK+ + + +A+ Y H+ + H Sbjct: 187 RLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVH 246 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK EN+++ ++G +K+ DFGLS + ++ LHT CG+ + APE++ + Y G + Sbjct: 247 RDLKIENIMISSSGEIKIIDFGLSNIFDYRKQ---LHTFCGSLYFAAPELLKAQPYTGPE 303 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS G++L+VL+ G +PF+D N L++KI K PS S L+ +++ +P Sbjct: 304 VDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPL 363 Query: 542 TRITI 556 R T+ Sbjct: 364 RRATL 368
>DCAK2_HUMAN (Q8N568) Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 2) Length = 766 Score = 141 bits (355), Expect = 1e-33 Identities = 80/193 (41%), Positives = 113/193 (58%), Gaps = 10/193 (5%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 + E M + T++++VMELV GG+LFD I S + E D L NA+ Y H + HR Sbjct: 455 LVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHR 514 Query: 185 DLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 D+KPENLL+ D +LK+ DFGL+ + +G L+T CGTP YVAPE+I GY Sbjct: 515 DIKPENLLVCEYPDGTKSLKLGDFGLATV-----VEGPLYTVCGTPTYVAPEIIAETGY- 568 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMA--LYKKIY--KADFSCPSW--FSTSAKKLI 514 G K D+W+ GVI ++L+ G+ PF N + L+ +I K +F P W + SAK+LI Sbjct: 569 GLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELI 628 Query: 515 KKILDPNPNTRIT 553 ++L N R T Sbjct: 629 SQMLQVNVEARCT 641
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 140 bits (354), Expect = 2e-33 Identities = 70/185 (37%), Positives = 107/185 (57%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +++Y++++ GGELF ++ R + + Y +QL A+ YCHS+ V H Sbjct: 202 RLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKVIH 261 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL +NG LK++DFG S + R T CGT +Y+ PE+I + +D Sbjct: 262 RDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD-ET 316 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLWS GV+ + + G PFE Y++I K +F P + S A+ L+ K+L NPN Sbjct: 317 VDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLLKHNPN 376 Query: 542 TRITI 556 R+ + Sbjct: 377 HRLPL 381
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 140 bits (352), Expect = 3e-33 Identities = 80/191 (41%), Positives = 113/191 (59%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ AV +CH GV H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVH 134 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Y Sbjct: 135 RDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKEAY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI + Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>DCAK1_HUMAN (O15075) Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1)| (Doublecortin-like and CAM kinase-like 1) Length = 740 Score = 140 bits (352), Expect = 3e-33 Identities = 81/184 (44%), Positives = 111/184 (60%), Gaps = 10/184 (5%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 + E M T++Y+VMELV GG+LFD I S + E DA L +A+ Y HS + HR Sbjct: 451 LIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHR 510 Query: 185 DLKPENLLL----DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 D+KPENLL+ D + +LK+ DFGL+ + DG L+T CGTP YVAPE+I GY Sbjct: 511 DIKPENLLVYEHQDGSKSLKLGDFGLATI-----VDGPLYTVCGTPTYVAPEIIAETGY- 564 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDS--NLMALYKKIY--KADFSCPSW--FSTSAKKLI 514 G K D+W+ GVI ++L+ G+ PF S + L+ +I + DF P W S SAK+LI Sbjct: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624 Query: 515 KKIL 526 +L Sbjct: 625 TMML 628
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 140 bits (352), Expect = 3e-33 Identities = 80/191 (41%), Positives = 113/191 (59%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ AV +CH GV H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVH 134 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Y Sbjct: 135 RDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKEAY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI + Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 140 bits (352), Expect = 3e-33 Identities = 80/191 (41%), Positives = 113/191 (59%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ AV +CH GV H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVH 134 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ Q + GTP Y++PEV+ + Y Sbjct: 135 RDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKEAY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI + Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 139 bits (351), Expect = 4e-33 Identities = 66/183 (36%), Positives = 114/183 (62%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ EDD + Y +L A+++ HS G+ + Sbjct: 168 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVY 227 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLDA+G +KV+DFGLS + + + ++ CGT Y+APEVIN +G+ A Sbjct: 228 RDLKPENILLDADGHIKVTDFGLS--KEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMA- 284 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G+LPF+ + +I KA S P + + A+ L++ + N Sbjct: 285 ADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQ 344 Query: 542 TRI 550 R+ Sbjct: 345 NRL 347 Score = 115 bits (288), Expect = 8e-26 Identities = 72/196 (36%), Positives = 107/196 (54%), Gaps = 12/196 (6%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRL-KEDDARKYFQQLINAVDYCHSRGVY 178 ++++V T IY++ EL GGEL DK+ ++ L E + L+NAV Y HS+ V Sbjct: 510 KLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVA 569 Query: 179 HRDLKPENLLLDAN----GTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKG 346 HRDL N+L +L++ DFG + S+ E+G+L T C T +VAPEV+ +G Sbjct: 570 HRDLTAANILFALKDGDPSSLRIVDFGFAKQSRA--ENGMLMTPCYTAQFVAPEVLRKQG 627 Query: 347 YDGAKADLWSCGVILFVLMAGYLPF----EDSNLMALYK-KIYKADFSCPSW--FSTSAK 505 YD D+WS GV+L ++ G PF D+ L + K + P W S AK Sbjct: 628 YD-RSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 686 Query: 506 KLIKKILDPNPNTRIT 553 L++K+LD +PN R+T Sbjct: 687 DLVRKMLDVDPNRRVT 702
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 139 bits (351), Expect = 4e-33 Identities = 79/191 (41%), Positives = 112/191 (58%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVH 134 Query: 182 RDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Y Sbjct: 135 RDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDPY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI K Sbjct: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 139 bits (351), Expect = 4e-33 Identities = 79/191 (41%), Positives = 112/191 (58%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA QQ++ +V++CH G+ H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVH 134 Query: 182 RDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL +K++DFGL+ Q + GTP Y++PEV+ Y Sbjct: 135 RDLKPENLLLASKSKGAAVKLADFGLAIEVQ--GDQQAWFGFAGTPGYLSPEVLRKDPY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI K Sbjct: 192 GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINK 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 139 bits (350), Expect = 5e-33 Identities = 73/178 (41%), Positives = 108/178 (60%), Gaps = 5/178 (2%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA 217 ++V+E GG+LFDKI + ED A+ YF QL+ + + HS+GV HRDLKPEN+LLD Sbjct: 88 WVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHSKGVAHRDLKPENILLDY 147 Query: 218 NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFV 397 NG LK+SDFG ++L + LL++ G+P Y APE+ + YDG+K D+WSCG+ILF Sbjct: 148 NGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEI--TQQYDGSKVDVWSCGIILFA 205 Query: 398 LMAGYLPFEDSNLMALYKKIYKADFSCPSW-----FSTSAKKLIKKILDPNPNTRITI 556 L+ G P++++ +YK PS+ S A +I +L +P R ++ Sbjct: 206 LLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFKRYSV 263
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 139 bits (349), Expect = 7e-33 Identities = 71/185 (38%), Positives = 107/185 (57%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y T+IY+++E GGEL+ ++ +L + Q+L +A+ YCH + V H Sbjct: 78 RLYNYFYDDTRIYLILEYAPGGELYKELQRHQKLDQQRTATIIQELSDALTYCHEKKVIH 137 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL NG +K+SDFG S + +R T CGT +Y+ PE+I K Y+ Sbjct: 138 RDIKPENLLLGLNGEVKISDFGWSVHTPSLRR----KTMCGTLDYLPPEMIAQKPYN-EM 192 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLW GV+ + L+ G PFE S Y++I + DF PS A+ LI K+L +P+ Sbjct: 193 VDLWCIGVLCYELLVGKPPFESSTSSETYRRIRQVDFKFPSSVPAGAQDLISKLLRYHPS 252 Query: 542 TRITI 556 R+++ Sbjct: 253 ERLSL 257
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 139 bits (349), Expect = 7e-33 Identities = 65/182 (35%), Positives = 106/182 (58%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 +Y+ K+Y++ E V GGE+F + + A+ Y +++ A+++ H + + +R Sbjct: 399 LYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVLALEFLHKQNIVYR 458 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 DLKPENLL+D G +K++DFG + R + T CGTP Y+APE+I +KG+ G Sbjct: 459 DLKPENLLIDNQGHIKITDFGFAK-----RVEDRTFTLCGTPEYLAPEIIQSKGH-GKAV 512 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNT 544 D W+ G+++F ++AGY PF D + A+Y KI + P F AK LIK++L + Sbjct: 513 DWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRLLTADRTR 572 Query: 545 RI 550 R+ Sbjct: 573 RL 574
>CHK1_DROME (O61661) Serine/threonine-protein kinase grp (EC 2.7.11.1) (Protein| grapes) (Chk1 homolog) Length = 512 Score = 139 bits (349), Expect = 7e-33 Identities = 74/178 (41%), Positives = 110/178 (61%), Gaps = 5/178 (2%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA 217 YI +E GGELFD+I + + +A++YF QL++ ++Y H RG+ HRDLKPENLLLD Sbjct: 94 YIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDE 153 Query: 218 NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFV 397 + +K+SDFG++ + + ++ LL CGT YVAPEV+ K Y ADLWSCGVIL Sbjct: 154 HDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSCGVILVT 212 Query: 398 LMAGYLPFEDSNLMALYKKIYKAD----FSCP-SWFSTSAKKLIKKILDPNPNTRITI 556 ++AG LP++ + ++ + P S T A L++K+L +P TR+T+ Sbjct: 213 MLAGELPWDQPSTNCTEFTNWRDNDHWQLQTPWSKLDTLAISLLRKLLATSPGTRLTL 270
>KCC1_SCHPO (Q9P7I2) Calcium/calmodulin-dependent protein kinase type I (EC| 2.7.11.17) (CaMK-I) Length = 335 Score = 138 bits (348), Expect = 9e-33 Identities = 75/180 (41%), Positives = 107/180 (59%), Gaps = 7/180 (3%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL- 211 +Y++ EL TGGELFD+I ++G E DA + +AV Y H G+ HRDLKPENLL Sbjct: 104 LYLITELATGGELFDRICAKGSFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPENLLYR 163 Query: 212 --DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGV 385 D N L ++DFGLS + + +L T CGTP Y+APEV GY G D+W+ GV Sbjct: 164 SKDPNSDLLIADFGLSHFYED-SQYYMLMTACGTPEYMAPEVFRRTGY-GKPVDMWAIGV 221 Query: 386 ILFVLMAGYLPFEDSNLMALYKKIYKADFS----CPSWFSTSAKKLIKKILDPNPNTRIT 553 I + L++GY PF + + + + I +++ C S S +AK IKK L+ +P+ R+T Sbjct: 222 ITYFLLSGYTPFARPSQVEVIEAILANEYTFNDPCWSGISETAKDFIKKCLENDPSKRLT 281
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 138 bits (347), Expect = 1e-32 Identities = 77/195 (39%), Positives = 122/195 (62%), Gaps = 10/195 (5%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSR-GVY 178 R+ + S+ ++I++E+ GG+LFDKI + D A+ YFQQL++A++Y H GV Sbjct: 80 RLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVECGVA 139 Query: 179 HRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTC---GTPNYVAPEVI-NNKG 346 HRD+KPEN+LLD NG LK++DFGL+ SQ R+DG L + G+P Y+APEV+ + +G Sbjct: 140 HRDIKPENILLDKNGNLKLADFGLA--SQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEG 197 Query: 347 YDGAKADLWSCGVILFVLMAGYLPF-----EDSNLMALYKKIYKADFSCPSWFSTSAKKL 511 Y + D+WS G++LFVL+ G P+ E+ + + + ++ S + L Sbjct: 198 YYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGNLNWGPWSKIEFTHLNL 257 Query: 512 IKKILDPNPNTRITI 556 ++KIL P+PN R+T+ Sbjct: 258 LRKILQPDPNKRVTL 272
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 137 bits (346), Expect = 2e-32 Identities = 69/166 (41%), Positives = 102/166 (61%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+V+E ++GGE+F + GR E +R Y Q++ A +Y HS + +RDLKPENLL Sbjct: 152 SNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLL 211 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D+ G LK++DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 212 IDSTGYLKITDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 265 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS K L+K +L Sbjct: 266 IYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLL 311
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 137 bits (345), Expect = 2e-32 Identities = 79/182 (43%), Positives = 110/182 (60%), Gaps = 7/182 (3%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 T +++VMEL GGELFD+I +G E A + + ++ V+ CHS GV HRDLKPEN L Sbjct: 106 TAVHLVMELCEGGELFDRIVQKGHYSERQAARLIKTIVEVVEACHSLGVMHRDLKPENFL 165 Query: 209 ---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSC 379 +D + LK +DFGLS + G+P YVAPEV+ K Y G ++D+WS Sbjct: 166 FDTIDEDAKLKATDFGLSVF---YKPGESFCDVVGSPYYVAPEVL-RKLY-GPESDVWSA 220 Query: 380 GVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIKKILDPNPNTR 547 GVIL++L++G PF + ++++I K DF W S SAK LI+K+LD NP TR Sbjct: 221 GVILYILLSGVPPFWAESEPGIFRQILLGKLDFHSEPWPSISDSAKDLIRKMLDQNPKTR 280 Query: 548 IT 553 +T Sbjct: 281 LT 282
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 137 bits (345), Expect = 2e-32 Identities = 64/182 (35%), Positives = 109/182 (59%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 ++ ++ K+Y+V++ V GGELF + GR E + Y ++++A+D+ H + + +R Sbjct: 216 LHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDIVYR 275 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 DLKPEN+LLD+ G + ++DFG LS+++ T CGTP Y+APEV+N G+ G Sbjct: 276 DLKPENILLDSEGHICITDFG---LSKKIETTDGTFTFCGTPEYLAPEVLNGHGH-GCAV 331 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNT 544 D WS G +L+ ++ G PF N+ +Y+KI + P++ S AK L++ +L + Sbjct: 332 DWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLLEGLLTREVDK 391 Query: 545 RI 550 R+ Sbjct: 392 RL 393
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 137 bits (344), Expect = 3e-32 Identities = 79/192 (41%), Positives = 114/192 (59%), Gaps = 8/192 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRG-RLKEDDARKYFQQLINAVDYCHSRGVY 178 + Y+ T +Y+VMEL GGEL D+I SRG + EDDA+ Q++N V +CH +GV Sbjct: 214 QFYDAFEDHTNVYVVMELCEGGELLDRILSRGGKYTEDDAKAVMIQILNVVAFCHLQGVV 273 Query: 179 HRDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 349 HRDLKPEN L D + LK DFG LS V+ D L+ G+ YVAPEV+ ++ Y Sbjct: 274 HRDLKPENFLFKSKDEDSQLKAIDFG---LSDYVKPDERLNDIVGSAYYVAPEVL-HRSY 329 Query: 350 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKAD--FSCPSW--FSTSAKKLIK 517 +AD+WS GVI ++L+ G PF +++ + KA+ F P W S+ AK +K Sbjct: 330 -STEADVWSIGVISYILLCGSRPFWARTESGIFRAVLKANLSFDEPPWPSVSSEAKDFVK 388 Query: 518 KILDPNPNTRIT 553 ++L+ +P R+T Sbjct: 389 RLLNKDPRKRMT 400
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 136 bits (343), Expect = 3e-32 Identities = 66/185 (35%), Positives = 108/185 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++E+ Y++ E V+GG+L D I G ++E ARK+ + + +A+ Y H+ + H Sbjct: 208 RLFEMCTLSNHFYMLFEYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVH 267 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK EN+++ + +K+ DFGLS + ++ LHT CG+ + APE++ Y G + Sbjct: 268 RDLKIENIMISDSSEIKIIDFGLSNIYDSRKQ---LHTFCGSLYFAAPELLKANPYTGPE 324 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS GV+LFVL+ G +PF+D N L++KI + P S L+ K+L +P Sbjct: 325 VDVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQGKVEYPQHLSIEVISLLSKMLVVDPK 384 Query: 542 TRITI 556 R T+ Sbjct: 385 RRATL 389
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 136 bits (342), Expect = 5e-32 Identities = 73/176 (41%), Positives = 104/176 (59%), Gaps = 3/176 (1%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA 217 Y+ +E +GGELFD+I + E +A+++FQQLI V Y HS G+ HRDLKPENLLLD Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSMGITHRDLKPENLLLDE 140 Query: 218 NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFV 397 LK+SDFGL+ + + + LL+ CGT YVAPE++ + D+W+CGV+L Sbjct: 141 RDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRAEPVDVWACGVVLTA 200 Query: 398 LMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKILDPNPNTRITI 556 ++AG LP++ S+ Y + W ++ L+ KIL NP RITI Sbjct: 201 MLAGELPWDQPSDSCQEYSDWKERKTYLAPWRKIDSAPLALLHKILTENPTARITI 256
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 135 bits (340), Expect = 8e-32 Identities = 64/183 (34%), Positives = 109/183 (59%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ E+D + Y +L A+D+ HS G+ + Sbjct: 123 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY 182 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + D ++ CGT Y+APEV+N +G+ Sbjct: 183 RDLKPENILLDEEGHIKITDFGLS--KEAIDHDKRAYSFCGTIEYMAPEVVNRRGHT-QS 239 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + NP Sbjct: 240 ADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPC 299 Query: 542 TRI 550 R+ Sbjct: 300 NRL 302 Score = 120 bits (301), Expect = 3e-27 Identities = 72/185 (38%), Positives = 111/185 (60%), Gaps = 12/185 (6%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL- 211 +Y+VMEL+ GGEL D+I + E +A + +DY HS+GV HRDLKP N+L Sbjct: 482 VYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYR 541 Query: 212 DANG---TLKVSDFGLSALSQQVRE-DGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSC 379 D +G +++V DFG ++Q+R +GLL T C T N+VAPEV+ +GYD A D+WS Sbjct: 542 DESGSPESIRVCDFG---FAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAA-CDIWSL 597 Query: 380 GVILFVLMAGYLPF---EDSNLMALYKKIYKADF--SCPSW--FSTSAKKLIKKILDPNP 538 G++L+ ++AG+ PF D + +I + S +W S +AK ++ K+L +P Sbjct: 598 GILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDP 657 Query: 539 NTRIT 553 + R+T Sbjct: 658 HQRLT 662
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 135 bits (340), Expect = 8e-32 Identities = 79/183 (43%), Positives = 106/183 (57%), Gaps = 11/183 (6%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL-- 211 YIV+EL+ GGELFDK+ RLKE + YF Q++ AV Y H G+ HRDLKPEN+LL Sbjct: 298 YIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSS 357 Query: 212 -DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEV---INNKGYDGAKADLWSC 379 + + +K++DFG S + + E L+ T CGTP Y+APEV + GY+ A D WS Sbjct: 358 QEEDCLIKITDFGHSKI---LGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRA-VDCWSL 413 Query: 380 GVILFVLMAGYLPFEDSNLMALYKKIY---KADFSCPSWFSTSAK--KLIKKILDPNPNT 544 GVILF+ ++GY PF + K K +F W S K L+KK+L +P Sbjct: 414 GVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKA 473 Query: 545 RIT 553 R T Sbjct: 474 RFT 476
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 135 bits (340), Expect = 8e-32 Identities = 66/185 (35%), Positives = 106/185 (57%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y T++Y+++E G ++ ++ + E Y +L NA+ YCHS+ V H Sbjct: 186 RLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIH 245 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL +NG LK++DFG S + R T CGT +Y+ PE+I + +D K Sbjct: 246 RDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TMCGTLDYLPPEMIEGRMHD-EK 300 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLWS GV+ + + G PFE Y++I + +F+ P + + A+ LI ++L N + Sbjct: 301 VDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNAS 360 Query: 542 TRITI 556 R+T+ Sbjct: 361 QRLTL 365
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 135 bits (340), Expect = 8e-32 Identities = 71/176 (40%), Positives = 104/176 (59%), Gaps = 3/176 (1%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA 217 Y+ +E +GGELFD+I + E DA+++F QL+ V Y H G+ HRD+KPENLLLD Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140 Query: 218 NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFV 397 LK+SDFGL+ + + + LL+ CGT YVAPE++ K + D+WSCG++L Sbjct: 141 RDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSCGIVLTA 200 Query: 398 LMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKILDPNPNTRITI 556 ++AG LP++ S+ Y + W ++ L+ KIL NP+ RITI Sbjct: 201 MLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITI 256
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 135 bits (339), Expect = 1e-31 Identities = 63/183 (34%), Positives = 109/183 (59%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++ + K+Y++++ + GG+LF +++ E+D + Y +L +D+ HS G+ + Sbjct: 126 RLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIY 185 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + + ++ CGT Y+APEV+N +G+ + Sbjct: 186 RDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS- 242 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + NP Sbjct: 243 ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNPT 302 Query: 542 TRI 550 R+ Sbjct: 303 NRL 305 Score = 115 bits (289), Expect = 6e-26 Identities = 71/193 (36%), Positives = 111/193 (57%), Gaps = 12/193 (6%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 +V IY+V EL+ GGEL D+I + E +A + V+ HS+GV HRDL Sbjct: 475 DVYKEGNSIYVVTELMRGGELLDRILRQKFFSEREASSVLFTVCKTVENLHSQGVVHRDL 534 Query: 191 KPENLL-LDANG---TLKVSDFGLSALSQQVRED-GLLHTTCGTPNYVAPEVINNKGYDG 355 KP N+L +D +G ++++ DFG ++Q+R D GLL T C T N+VAPEV+ +GYD Sbjct: 535 KPSNILYVDESGDPESIRICDFG---FAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDE 591 Query: 356 AKADLWSCGVILFVLMAGYLPFED---SNLMALYKKIYKADFSC--PSW--FSTSAKKLI 514 D+WS G++L+ ++AGY PF + + +I F+ +W S +AK L+ Sbjct: 592 G-CDIWSLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTLRGGNWNTVSAAAKDLV 650 Query: 515 KKILDPNPNTRIT 553 ++L +P+ R+T Sbjct: 651 SRMLHVDPHKRLT 663
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 135 bits (339), Expect = 1e-31 Identities = 77/182 (42%), Positives = 106/182 (58%), Gaps = 10/182 (5%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL-- 211 YIV+EL+ GGELFD++ RLKE + YF Q++ AV Y H G+ HRDLKPEN+LL Sbjct: 302 YIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSS 361 Query: 212 -DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG--AKADLWSCG 382 + + +K++DFG S + + E L+ T CGTP Y+APEV+ + G G D WS G Sbjct: 362 QEEDCLIKITDFGQSKI---LGETSLMRTLCGTPTYLAPEVLVSNGTAGYSRAVDCWSLG 418 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIY---KADFSCPSW--FSTSAKKLIKKILDPNPNTR 547 VILF+ ++GY PF + K K +F W S A L+KK+L +P R Sbjct: 419 VILFICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKAR 478 Query: 548 IT 553 +T Sbjct: 479 LT 480
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 135 bits (339), Expect = 1e-31 Identities = 63/183 (34%), Positives = 110/183 (60%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ E+D + Y +L +D+ HS G+ + Sbjct: 126 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIY 185 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + + ++ CGT Y+APEV+N +G+ + Sbjct: 186 RDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS- 242 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + ST A+ L++ + NP Sbjct: 243 ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPA 302 Query: 542 TRI 550 R+ Sbjct: 303 NRL 305 Score = 120 bits (300), Expect = 3e-27 Identities = 73/184 (39%), Positives = 107/184 (58%), Gaps = 11/184 (5%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL-L 211 +Y+V EL+ GGEL DKI + E +A + V+Y HS+GV HRDLKP N+L + Sbjct: 485 VYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYV 544 Query: 212 DANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 D +G L++ DFG + Q E+GLL T C T N+VAPEV+ +GYD D+WS G Sbjct: 545 DESGNPECLRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG-CDIWSLG 601 Query: 383 VILFVLMAGYLPFED---SNLMALYKKIYKADF--SCPSW--FSTSAKKLIKKILDPNPN 541 ++L+ ++AGY PF + + +I F S +W S +AK L+ K+L +P+ Sbjct: 602 ILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPH 661 Query: 542 TRIT 553 R+T Sbjct: 662 QRLT 665
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 135 bits (339), Expect = 1e-31 Identities = 63/183 (34%), Positives = 109/183 (59%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ E+D + Y +L A+D+ HS G+ + Sbjct: 132 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY 191 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + + ++ CGT Y+APEV+N +G+ Sbjct: 192 RDLKPENILLDEEGHIKLTDFGLS--KESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QS 248 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + NP Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308 Query: 542 TRI 550 R+ Sbjct: 309 NRL 311 Score = 124 bits (311), Expect = 2e-28 Identities = 72/184 (39%), Positives = 107/184 (58%), Gaps = 11/184 (5%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL-L 211 +Y+V EL+ GGEL DKI + E +A + V+Y H++GV HRDLKP N+L + Sbjct: 489 VYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYV 548 Query: 212 DANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 D +G ++++ DFG + Q E+GLL T C T N+VAPEV+ +GYD A D+WS G Sbjct: 549 DESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDAA-CDIWSLG 605 Query: 383 VILFVLMAGYLPF---EDSNLMALYKKIYKADFSCPSWF----STSAKKLIKKILDPNPN 541 V+L+ ++ GY PF D + +I FS + S +AK L+ K+L +P+ Sbjct: 606 VLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPH 665 Query: 542 TRIT 553 R+T Sbjct: 666 QRLT 669
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 135 bits (339), Expect = 1e-31 Identities = 63/183 (34%), Positives = 109/183 (59%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ E+D + Y +L A+D+ HS G+ + Sbjct: 132 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY 191 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + + ++ CGT Y+APEV+N +G+ Sbjct: 192 RDLKPENILLDEEGHIKLTDFGLS--KESIDHEKKAYSFCGTVEYMAPEVVNRRGHT-QS 248 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + NP Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308 Query: 542 TRI 550 R+ Sbjct: 309 NRL 311 Score = 124 bits (311), Expect = 2e-28 Identities = 72/184 (39%), Positives = 107/184 (58%), Gaps = 11/184 (5%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL-L 211 +Y+V EL+ GGEL DKI + E +A + V+Y H++GV HRDLKP N+L + Sbjct: 489 VYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYV 548 Query: 212 DANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 D +G ++++ DFG + Q E+GLL T C T N+VAPEV+ +GYD A D+WS G Sbjct: 549 DESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDAA-CDIWSLG 605 Query: 383 VILFVLMAGYLPF---EDSNLMALYKKIYKADFSCPSWF----STSAKKLIKKILDPNPN 541 V+L+ ++ GY PF D + +I FS + S +AK L+ K+L +P+ Sbjct: 606 VLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPH 665 Query: 542 TRIT 553 R+T Sbjct: 666 QRLT 669
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 135 bits (339), Expect = 1e-31 Identities = 72/186 (38%), Positives = 105/186 (56%), Gaps = 1/186 (0%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +IY+++E GEL+ + R E+ A KY Q+ NA+ Y H + V H Sbjct: 151 RLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKKHVIH 210 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPEN+LL +G +K+SDFG S + R T CGT +Y+ PE++ K + K Sbjct: 211 RDIKPENILLGIDGEIKLSDFGWSVHAPSNRRT----TLCGTLDYLPPEMVEGKEHT-EK 265 Query: 362 ADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 538 DLWS GV+ + + G PFED S A YK+I K D PS+ A+ LI ++L NP Sbjct: 266 VDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVDLKIPSFVPPDARDLISRLLQHNP 325 Query: 539 NTRITI 556 R+++ Sbjct: 326 EKRMSL 331
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 134 bits (338), Expect = 1e-31 Identities = 63/183 (34%), Positives = 110/183 (60%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ E+D + Y +L +D+ HS G+ + Sbjct: 126 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIY 185 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + + ++ CGT Y+APEV+N +G+ + Sbjct: 186 RDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHS- 242 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + ST A+ L++ + NP Sbjct: 243 ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPA 302 Query: 542 TRI 550 R+ Sbjct: 303 NRL 305 Score = 121 bits (303), Expect = 2e-27 Identities = 74/184 (40%), Positives = 107/184 (58%), Gaps = 11/184 (5%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL-L 211 +Y+V EL+ GGEL DKI + E +A + V+Y HS+GV HRDLKP N+L + Sbjct: 485 VYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQGVVHRDLKPSNILYV 544 Query: 212 DANGT---LKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 D +G L++ DFG + Q E+GLL T C T N+VAPEV+ +GYD D+WS G Sbjct: 545 DESGNPECLRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG-CDIWSLG 601 Query: 383 VILFVLMAGYLPFED---SNLMALYKKIYKADF--SCPSW--FSTSAKKLIKKILDPNPN 541 V+L+ ++AGY PF + + +I F S +W S +AK L+ K+L +P+ Sbjct: 602 VLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTLSGGNWNTVSETAKDLVSKMLHVDPH 661 Query: 542 TRIT 553 R+T Sbjct: 662 QRLT 665
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 134 bits (337), Expect = 2e-31 Identities = 69/183 (37%), Positives = 104/183 (56%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 RM+ I++VM+ + GGELF + R A+ Y ++I A++Y H+ + + Sbjct: 132 RMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIY 191 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD NG +K++DFG + Q V T CGTP+Y+APEVI K Y+ Sbjct: 192 RDLKPENILLDRNGHIKITDFGFAKEVQTV-----TWTLCGTPDYIAPEVITTKPYN-KS 245 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D WS GV+++ ++AGY PF D+ M Y+KI + P +F L+ K++ + Sbjct: 246 VDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLT 305 Query: 542 TRI 550 RI Sbjct: 306 RRI 308
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 134 bits (337), Expect = 2e-31 Identities = 66/185 (35%), Positives = 105/185 (56%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y T++Y+++E G ++ ++ + E Y +L NA+ YCHS+ V H Sbjct: 188 RLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIH 247 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL +NG LK++DFG S + R T CGT +Y PE+I + +D K Sbjct: 248 RDIKPENLLLGSNGELKIADFGWSVHAPSSRRT----TLCGTLDYQPPEMIEGRMHD-EK 302 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLWS GV+ + + G PFE Y++I + +F+ P + + A+ LI ++L N + Sbjct: 303 VDLWSLGVLCYEFLVGMPPFEAHTYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNSS 362 Query: 542 TRITI 556 R+T+ Sbjct: 363 QRLTL 367
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 134 bits (337), Expect = 2e-31 Identities = 70/175 (40%), Positives = 102/175 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + + Sbjct: 152 RLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY 211 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A Sbjct: 212 RDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA- 265 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 266 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 320
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 134 bits (337), Expect = 2e-31 Identities = 70/175 (40%), Positives = 102/175 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + + Sbjct: 105 RLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY 164 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A Sbjct: 165 RDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA- 218 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 219 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 134 bits (337), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 134 bits (337), Expect = 2e-31 Identities = 70/175 (40%), Positives = 102/175 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+ + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + + Sbjct: 105 RLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY 164 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLL+D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A Sbjct: 165 RDLKPENLLIDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA- 218 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 D W+ GV+++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 219 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KPSH2_HUMAN (Q96QS6) Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2)| Length = 385 Score = 134 bits (337), Expect = 2e-31 Identities = 74/182 (40%), Positives = 112/182 (61%), Gaps = 7/182 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++ E+ + ++Y+VMEL TGGELFD++ ++G E DA + Q + + + Y H+ + H Sbjct: 122 QLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITH 181 Query: 182 RDLKPENLLLDANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 R+LKPENLL G + ++DFGL A S + D + T CGTP Y+APEV+ K Y Sbjct: 182 RNLKPENLLYYHPGEESKILITDFGL-AYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYT 240 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTS--AKKLIKK 520 A D+W+ GVI + L++G+LPF+D + LY+KI K +++ W S S AK I K Sbjct: 241 SA-VDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDK 299 Query: 521 IL 526 +L Sbjct: 300 LL 301
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 134 bits (336), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 113 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 172 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 173 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 226 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 227 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 272
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 134 bits (336), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 134 bits (336), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 134 bits (336), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 134 bits (336), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 134 bits (336), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 134 bits (336), Expect = 2e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDQQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 134 bits (336), Expect = 2e-31 Identities = 77/190 (40%), Positives = 112/190 (58%), Gaps = 5/190 (2%) Frame = +2 Query: 2 RMYEVM-ASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVY 178 + YE+ S +IYI+MEL G+L + I +G L ED ARK F+QL +AV YCH + Sbjct: 74 KTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIV 133 Query: 179 HRDLKPENLLLDANGTLKVSDFGLS--ALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 HRDLK ENLLLD + +K+SDFG S L L T CG+ Y APEV+ + Y Sbjct: 134 HRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQ 193 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNL--MALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 D+WS GVIL++++ G +P++DS++ M +K ++ DF + K LI ++L Sbjct: 194 PKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRML 253 Query: 527 DPNPNTRITI 556 P+ + R+ I Sbjct: 254 QPDVSQRLHI 263
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 133 bits (335), Expect = 3e-31 Identities = 63/183 (34%), Positives = 107/183 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ E+D + Y +L A+D+ H G+ + Sbjct: 123 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIY 182 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + D ++ CGT Y+APEV+N +G+ Sbjct: 183 RDLKPENILLDEEGHIKITDFGLS--KEATDHDKRAYSFCGTIEYMAPEVVNRRGHT-QS 239 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + NP Sbjct: 240 ADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPC 299 Query: 542 TRI 550 R+ Sbjct: 300 NRL 302 Score = 123 bits (308), Expect = 4e-28 Identities = 71/184 (38%), Positives = 109/184 (59%), Gaps = 11/184 (5%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL-L 211 +Y+VMEL+ GGEL D+I + E +A + +DY HS+GV HRDLKP N+L + Sbjct: 482 VYLVMELMRGGELLDRILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILYM 541 Query: 212 DANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 D +G ++++ DFG + Q E+GLL T C T N+VAPEV+ +GYD A D+WS G Sbjct: 542 DESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDAA-CDVWSLG 598 Query: 383 VILFVLMAGYLPF---EDSNLMALYKKIYKADF--SCPSW--FSTSAKKLIKKILDPNPN 541 ++L+ ++AG+ PF D + +I + S +W S +AK ++ K+L +P Sbjct: 599 ILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQ 658 Query: 542 TRIT 553 R+T Sbjct: 659 QRLT 662
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 133 bits (335), Expect = 3e-31 Identities = 66/182 (36%), Positives = 104/182 (57%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y T++Y+++E G ++ ++ + E Y +L NA+ YCHS+ V H Sbjct: 195 RLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIH 254 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL + G LK++DFG S + R T CGT +Y+ PE+I + +D K Sbjct: 255 RDIKPENLLLGSAGELKIADFGWSVHAPSSRRT----TLCGTLDYLPPEMIEGRMHD-EK 309 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLWS GV+ + + G PFE + YK+I + +F+ P + + A+ LI ++L NP+ Sbjct: 310 VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPS 369 Query: 542 TR 547 R Sbjct: 370 QR 371
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 133 bits (335), Expect = 3e-31 Identities = 70/176 (39%), Positives = 104/176 (59%), Gaps = 3/176 (1%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA 217 Y+ +E +GGELFD+I + E DA+++F QL+ V Y H G+ HRD+KPENLLLD Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140 Query: 218 NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFV 397 LK+SDFGL+ + + + LL+ CGT YVAPE++ + + D+WSCG++L Sbjct: 141 RDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTA 200 Query: 398 LMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKILDPNPNTRITI 556 ++AG LP++ S+ Y + W ++ L+ KIL NP+ RITI Sbjct: 201 MLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITI 256
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 133 bits (335), Expect = 3e-31 Identities = 78/187 (41%), Positives = 107/187 (57%), Gaps = 7/187 (3%) Frame = +2 Query: 14 VMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLK 193 V R +++VMEL GGELFD+I ++G E A +Q++N V CH GV HRDLK Sbjct: 148 VFEDRQSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVCHFMGVMHRDLK 207 Query: 194 PENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 PEN LL D + LK +DFGLS + E + G+ YVAPEV+ + Y G + Sbjct: 208 PENFLLSSKDKDAMLKATDFGLSVF---IEEGKVYRNIVGSAYYVAPEVL-RRSY-GKEI 262 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDP 532 D+WS GVIL++L++G PF N ++ I + DF W S SAK L++K+L Sbjct: 263 DIWSAGVILYILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNSAKDLVRKMLTQ 322 Query: 533 NPNTRIT 553 +P RIT Sbjct: 323 DPRRRIT 329
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 133 bits (335), Expect = 3e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 133 bits (335), Expect = 3e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 133 bits (335), Expect = 3e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 133 bits (335), Expect = 3e-31 Identities = 69/166 (41%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+VME V GGE+F + GR E AR Y Q++ +Y HS + +RDLKPENLL Sbjct: 114 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 173 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D G ++V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 174 IDHQGYIQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 227 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS FS+ K L++ +L Sbjct: 228 IYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 273
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 133 bits (334), Expect = 4e-31 Identities = 79/192 (41%), Positives = 108/192 (56%), Gaps = 7/192 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++YE + IY++MEL +G ELFD I G E +A +Q+ +A+ Y HS + H Sbjct: 130 KLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVH 189 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPEN L + + LK+ DFG LS+ + T GTP YVAP+V++ K YD Sbjct: 190 RDLKPENFLFQSENKDSLLKIIDFG---LSKNLGTGEFTTTKAGTPYYVAPQVLDGK-YD 245 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSW--FSTSAKKLIKK 520 K D+WS GVI++ L+ GY PF + KK+ K +F W S+ AK LI K Sbjct: 246 -KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITK 304 Query: 521 ILDPNPNTRITI 556 +L NPN R TI Sbjct: 305 LLTYNPNERCTI 316
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 133 bits (334), Expect = 4e-31 Identities = 70/176 (39%), Positives = 103/176 (58%), Gaps = 3/176 (1%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDA 217 Y+ +E +GGELFD+I + E DA+++F QL+ V Y H G+ HRD+KPENLLLD Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140 Query: 218 NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFV 397 LK+SDFGL+ + + + LL+ CGT YVAPE++ K + D+WSCG++L Sbjct: 141 RDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSCGIVLTA 200 Query: 398 LMAGYLPFED-SNLMALYKKIYKADFSCPSW--FSTSAKKLIKKILDPNPNTRITI 556 ++AG LP++ S+ Y + W ++ L+ KIL P+ RITI Sbjct: 201 MLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVETPSARITI 256
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 133 bits (334), Expect = 4e-31 Identities = 73/187 (39%), Positives = 115/187 (61%), Gaps = 2/187 (1%) Frame = +2 Query: 2 RMYEVMASRT-KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVY 178 ++YE++ S KIY+VMEL GG++FD + + G L E A+ F+Q++ A+ YCH GV Sbjct: 72 QVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVA 131 Query: 179 HRDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGA 358 HRDLK EN LL LK++DFG + + + R + L T CG+ Y APEV+ +D Sbjct: 132 HRDLKCENALLQ-GFNLKLTDFGFAKVLPKSRRE-LSQTFCGSTAYAAPEVLQGIPHDSK 189 Query: 359 KADLWSCGVILFVLMAGYLPFEDSNL-MALYKKIYKADFSCPSWFSTSAKKLIKKILDPN 535 K D+WS GV+L+V++ LPF+D+++ L+++ F ST + L+K++L+P+ Sbjct: 190 KGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLGISTECQDLLKRLLEPD 249 Query: 536 PNTRITI 556 R +I Sbjct: 250 MILRPSI 256
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 133 bits (334), Expect = 4e-31 Identities = 79/192 (41%), Positives = 108/192 (56%), Gaps = 7/192 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++YE + IY++MEL +G ELFD I G E +A +Q+ +A+ Y HS + H Sbjct: 130 KLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVH 189 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPEN L + + LK+ DFG LS+ + T GTP YVAP+V++ K YD Sbjct: 190 RDLKPENFLFQSENKDSLLKIIDFG---LSKNLGTGEFTTTKAGTPYYVAPQVLDGK-YD 245 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSC--PSW--FSTSAKKLIKK 520 K D+WS GVI++ L+ GY PF + KK+ K +F W S+ AK LI K Sbjct: 246 -KKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITK 304 Query: 521 ILDPNPNTRITI 556 +L NPN R TI Sbjct: 305 LLTYNPNERCTI 316
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 133 bits (334), Expect = 4e-31 Identities = 62/183 (33%), Positives = 109/183 (59%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG+LF +++ E+D + Y +L +D+ HS G+ + Sbjct: 144 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIY 203 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + + ++ CGT Y+APEV+N +G+ + Sbjct: 204 RDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS- 260 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + NP Sbjct: 261 ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPA 320 Query: 542 TRI 550 R+ Sbjct: 321 NRL 323 Score = 118 bits (295), Expect = 1e-26 Identities = 72/184 (39%), Positives = 106/184 (57%), Gaps = 11/184 (5%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL-L 211 +Y+V EL+ GGEL DKI + E +A + V+Y HS+GV HRDLKP N+L + Sbjct: 502 VYLVTELMRGGELLDKILRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYV 561 Query: 212 DANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 D +G ++++ DFG + Q E+GLL T C T N+VAPEV+ +GYD D+WS G Sbjct: 562 DESGNPESIRICDFGFA--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG-CDIWSLG 618 Query: 383 VILFVLMAGYLPFED---SNLMALYKKIYKADFSC--PSW--FSTSAKKLIKKILDPNPN 541 V+L+ ++AG PF + + +I FS +W S AK L+ K+L +P+ Sbjct: 619 VLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAKDLVSKMLHVDPH 678 Query: 542 TRIT 553 R+T Sbjct: 679 QRLT 682
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 132 bits (333), Expect = 5e-31 Identities = 62/183 (33%), Positives = 109/183 (59%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ + K+Y++++ + GG++F +++ E+D + Y +L A+D+ H G+ + Sbjct: 137 KLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVY 196 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + V ++ ++ CGT Y+APEV+N +G+ Sbjct: 197 RDLKPENILLDEIGHIKLTDFGLS--KESVDQEKKAYSFCGTVEYMAPEVVNRRGH-SQS 253 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + NP Sbjct: 254 ADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPA 313 Query: 542 TRI 550 R+ Sbjct: 314 NRL 316 Score = 113 bits (282), Expect = 4e-25 Identities = 70/185 (37%), Positives = 106/185 (57%), Gaps = 12/185 (6%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL-L 211 +Y+V +L+ GGEL D+I + E +A + VDY H +GV HRDLKP N+L + Sbjct: 493 VYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYM 552 Query: 212 DANG---TLKVSDFGLSALSQQVR-EDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSC 379 D + ++++ DFG ++Q+R E+GLL T C T N+VAPEV+ +GYD A D+WS Sbjct: 553 DESASADSIRICDFG---FAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAA-CDIWSL 608 Query: 380 GVILFVLMAGYLPF---EDSNLMALYKKIYKADFSCP--SW--FSTSAKKLIKKILDPNP 538 GV+ + ++AGY PF + + +I FS +W S AK L+ +L +P Sbjct: 609 GVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDP 668 Query: 539 NTRIT 553 + R T Sbjct: 669 HQRYT 673
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 132 bits (333), Expect = 5e-31 Identities = 78/179 (43%), Positives = 106/179 (59%), Gaps = 7/179 (3%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN-LLL 211 ++IVMEL GGELF KI RG E A + + ++ ++ CHS GV HRDLKPEN LLL Sbjct: 147 VHIVMELCAGGELFSKIQKRGHYSERKAAELIKIIVGIIETCHSHGVMHRDLKPENFLLL 206 Query: 212 DANG--TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGV 385 DA+ ++K DFGLS R + G+P Y+APEV+ + G +AD+W+ GV Sbjct: 207 DADDEFSVKAIDFGLSVF---FRPGQVFREVVGSPYYIAPEVLEKR--YGPEADIWTAGV 261 Query: 386 ILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIKKILDPNPNTRI 550 IL+VL+ G PF +Y+K+ + DF W S SAK LIKK+L P P+ R+ Sbjct: 262 ILYVLLTGVPPFWADTQSGIYEKVLDGRIDFKSNRWPRISDSAKDLIKKMLCPYPSERL 320
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 132 bits (333), Expect = 5e-31 Identities = 64/176 (36%), Positives = 110/176 (62%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 ++ ++Y+V++ + GG LF ++ +G +ED AR Y ++++AV + H +G+ HRDLKPEN Sbjct: 209 TKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPEN 268 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 +L+D +G + ++DFG L+++ E+ ++ CGT Y+APE++ KG+D A AD WS G Sbjct: 269 ILMDVDGHVMLTDFG---LAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKA-ADWWSVG 324 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 ++L+ ++ G PF S + +KI K P + S A L+K +L P R+ Sbjct: 325 ILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPERRL 379
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 132 bits (332), Expect = 7e-31 Identities = 68/166 (40%), Positives = 100/166 (60%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y+V+E V GGE+F + GR E +R Y Q++ A +Y H + +RDLKPENLL Sbjct: 116 SNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLL 175 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 +D+ G LKV+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+ Sbjct: 176 IDSQGYLKVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVL 229 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ + AGY PF + +Y+KI PS F + K L++ +L Sbjct: 230 VYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLL 275
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 132 bits (332), Expect = 7e-31 Identities = 66/164 (40%), Positives = 99/164 (60%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD 214 +Y++ME V GGELF + +RGR Y ++I A++Y HS+ + +RDLKPEN+LLD Sbjct: 122 LYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLD 181 Query: 215 ANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILF 394 +G +K++DFG + + T CGTP Y+APEVI +KG+ G D W+ G+++F Sbjct: 182 RDGHIKLTDFGFAK-----KLVDRTWTLCGTPEYLAPEVIQSKGH-GRAVDWWALGILIF 235 Query: 395 VLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 +++G+ PF D N +Y+KI P K LIKK+L Sbjct: 236 EMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLL 279
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 132 bits (332), Expect = 7e-31 Identities = 72/186 (38%), Positives = 106/186 (56%), Gaps = 4/186 (2%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++YEV+ + +K+++ +E G EL+D + S R+ + + F Q+ AV Y HS H Sbjct: 96 KLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVH 155 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLK EN+LLD NG K++DFG +++ L T CGT Y+APE+I + YDG K Sbjct: 156 RDLKLENILLDKNGNAKLTDFG---FTRECMTKTTLETVCGTTVYMAPELIERRTYDGFK 212 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSW----FSTSAKKLIKKILD 529 D+WS GVIL+ L+ GYLPF+D + KI + P + A+ LI ++L Sbjct: 213 IDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEE---PKYDAKVIPDDARDLISRLLA 269 Query: 530 PNPNTR 547 NP R Sbjct: 270 KNPGER 275
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 132 bits (332), Expect = 7e-31 Identities = 77/186 (41%), Positives = 105/186 (56%), Gaps = 9/186 (4%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 S+ K YIV +L TGGELFD+I SRG+ E DA + Q++ AV+Y HS+ V HRDLKPEN Sbjct: 117 SKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPEN 176 Query: 203 LLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLW 373 +L N L ++DFG++ Q E+ L++ G+ YVAPEV+ G+ G D+W Sbjct: 177 VLYVDKSENSPLVIADFGIA--KQLKGEEDLIYKAAGSLGYVAPEVLTQDGH-GKPCDIW 233 Query: 374 SCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSW--FSTSAKKLIKKILDPN 535 S GVI + L+ GY PF ++ ++ Y F P W S K+ I K L N Sbjct: 234 SIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLN 293 Query: 536 PNTRIT 553 P R T Sbjct: 294 PADRPT 299
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 132 bits (331), Expect = 9e-31 Identities = 63/176 (35%), Positives = 110/176 (62%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 ++ ++Y+V++ + GG LF ++ +G +ED AR Y ++++AV + H +G+ HRDLKPEN Sbjct: 203 TKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPEN 262 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 +L+D +G + ++DFG L+++ E+ ++ CGT Y+APE++ KG+D A AD WS G Sbjct: 263 ILMDTDGHVMLTDFG---LAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKA-ADWWSVG 318 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 ++L+ ++ G PF S + +KI K P + S A ++K +L P R+ Sbjct: 319 ILLYEMLTGKPPFLGSK-GKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRL 373
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 132 bits (331), Expect = 9e-31 Identities = 76/191 (39%), Positives = 110/191 (57%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA Q++ +V++ H + H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVH 134 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ Q E GTP Y++PEV+ Y Sbjct: 135 RDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GEQQAWFGFAGTPGYLSPEVLRKDPY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI + Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 132 bits (331), Expect = 9e-31 Identities = 76/191 (39%), Positives = 110/191 (57%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA Q++ +V++ H + H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVH 134 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ Q E GTP Y++PEV+ Y Sbjct: 135 RDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GEQQAWFGFAGTPGYLSPEVLRKDPY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI + Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 132 bits (331), Expect = 9e-31 Identities = 76/191 (39%), Positives = 110/191 (57%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+++ ++ Y+V +LVTGGELF+ I +R E DA Q++ +V++ H + H Sbjct: 75 RLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVH 134 Query: 182 RDLKPENLLLDA---NGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLLL + +K++DFGL+ Q E GTP Y++PEV+ Y Sbjct: 135 RDLKPENLLLASKCKGAAVKLADFGLAIEVQ--GEQQAWFGFAGTPGYLSPEVLRKDPY- 191 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKK 520 G D+W+CGVIL++L+ GY PF D + LY++I DF P W + AK LI + Sbjct: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251 Query: 521 ILDPNPNTRIT 553 +L NP RIT Sbjct: 252 MLTINPAKRIT 262
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 131 bits (330), Expect = 1e-30 Identities = 62/183 (33%), Positives = 107/183 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++ + K+Y++++ + GG+LF +++ E+D + Y +L +D+ HS G+ + Sbjct: 126 RLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIY 185 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+LLD G +K++DFGLS + + + ++ CGT Y+APEV+N +G+ Sbjct: 186 RDLKPENILLDEEGHIKLTDFGLS--KEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHG- 242 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 AD WS GV++F ++ G LPF+ + I KA P + S A+ L++ + N Sbjct: 243 ADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNAT 302 Query: 542 TRI 550 R+ Sbjct: 303 NRL 305 Score = 113 bits (283), Expect = 3e-25 Identities = 61/141 (43%), Positives = 87/141 (61%), Gaps = 4/141 (2%) Frame = +2 Query: 11 EVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDL 190 +V IY+V EL+ GGEL D+I + E +A + V+Y HS+GV HRDL Sbjct: 475 DVYEECNSIYLVTELMRGGELLDRILRQKFFSEREACSVLFTVCKTVEYLHSQGVVHRDL 534 Query: 191 KPENLL-LDANG---TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGA 358 KP N+L +D +G ++++ DFG S Q E+GLL T C T N+VAPEV+ +GYD Sbjct: 535 KPSNILYVDESGDPESIRICDFGFS--KQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG 592 Query: 359 KADLWSCGVILFVLMAGYLPF 421 D+WS G++L+ ++AGY PF Sbjct: 593 -CDIWSLGILLYTMLAGYTPF 612
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 131 bits (330), Expect = 1e-30 Identities = 69/164 (42%), Positives = 98/164 (59%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD 214 +Y+VME V GGE+F ++ GR E A Y Q++ AV Y HS + HRDLKPENLL+D Sbjct: 116 LYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLID 175 Query: 215 ANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILF 394 G L+V+DFG + R G T CGTP Y+APE+I +KGY+ A D W+ GV+++ Sbjct: 176 QQGYLQVTDFGFAK-----RVKGRTWTLCGTPEYLAPEIILSKGYNKA-VDWWALGVLIY 229 Query: 395 VLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 + G+ PF + +Y+KI PS S+ K L++ +L Sbjct: 230 EMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLL 273
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 131 bits (330), Expect = 1e-30 Identities = 65/164 (39%), Positives = 101/164 (61%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD 214 +Y++ME V GGELF + +RGR + Y +++ A++Y HS+ + +RDLKPEN+LLD Sbjct: 119 LYMLMEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLD 178 Query: 215 ANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILF 394 G +K++DFG + + T CGTP Y+APEVI +KG+ G D W+ G+++F Sbjct: 179 REGHIKLTDFGFAK-----KLVDRTWTLCGTPEYLAPEVIQSKGH-GRAVDWWALGILIF 232 Query: 395 VLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 +++G+ PF D N +Y+KI P ++K LIKK+L Sbjct: 233 EMLSGFPPFFDDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLL 276
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 131 bits (329), Expect = 1e-30 Identities = 68/186 (36%), Positives = 110/186 (59%), Gaps = 1/186 (0%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y ++Y++ME V GEL+ + + G L E A + Q+ NA+DY HS+ + H Sbjct: 162 QLYGFFYDEKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNILH 221 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLH-TTCGTPNYVAPEVINNKGYDGA 358 RD+KPEN+L+ N T+K++DFG S + EDG T CGT +Y++PE+I ++ Y+ Sbjct: 222 RDIKPENILIGFNNTIKLTDFGWSVYN----EDGQKRKTLCGTIDYLSPELIKSREYNN- 276 Query: 359 KADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 538 K D+W+ GV+ + L+ G PFE+ Y++I + D P S A+ LI ++L P Sbjct: 277 KVDVWALGVLTYELLVGSPPFEEDTKEMTYRRILRCDLKFPLNVSPQARDLIVRLLQFEP 336 Query: 539 NTRITI 556 + RI + Sbjct: 337 SKRIPL 342
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 131 bits (329), Expect = 1e-30 Identities = 73/187 (39%), Positives = 107/187 (57%), Gaps = 10/187 (5%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 S + +++V +L+ GELFD + + L E + R + L+ AV++ H + HRDLKPEN Sbjct: 99 SSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNIVHRDLKPEN 158 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI------NNKGYDGAKA 364 +LLD N +++SDFG S + L CGTP Y+APE++ + GY G + Sbjct: 159 ILLDDNMQIRLSDFGFSC---HLEPGEKLRELCGTPGYLAPEILKCSMDETHPGY-GKEV 214 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDP 532 DLW+CGVILF L+AG PF + + + I + FS P W S + K LI K+L Sbjct: 215 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLLQV 274 Query: 533 NPNTRIT 553 +PN R+T Sbjct: 275 DPNARLT 281
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 131 bits (329), Expect = 1e-30 Identities = 63/173 (36%), Positives = 103/173 (59%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 K+Y+++E ++GGELF + G ED A Y ++ A+ + HS+G+ +RDLKPEN++L Sbjct: 143 KLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIML 202 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 + G +K++DFGL + + E + HT CGT Y+APE++ G++ A D WS G ++ Sbjct: 203 SSQGHIKLTDFGL--CKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRA-VDWWSLGALM 259 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + ++ G PF N KI + + P + + A+ L+KK L NP+ RI Sbjct: 260 YDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRI 312
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 130 bits (328), Expect = 2e-30 Identities = 74/191 (38%), Positives = 110/191 (57%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++++V + Y+V E GGELF++I +R + E DA +Q+++ + Y H + H Sbjct: 129 KLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVH 188 Query: 182 RDLKPENLLLDANGTL---KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RD+KPEN+LL+ +L K+ DFGLS+ +D L GT Y+APEV+ K + Sbjct: 189 RDIKPENILLENKHSLLNIKIVDFGLSSF---FSKDNKLRDRLGTAYYIAPEVLRKKYNE 245 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSWFSTSAKKLIKK 520 K D+WSCGVIL++L+ GY PF N + KK+ Y DF+ S AK+LIK Sbjct: 246 --KCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKL 303 Query: 521 ILDPNPNTRIT 553 +L + N RIT Sbjct: 304 MLTYDYNKRIT 314
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 130 bits (328), Expect = 2e-30 Identities = 74/191 (38%), Positives = 110/191 (57%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++++V + Y+V E GGELF++I +R + E DA +Q+++ + Y H + H Sbjct: 129 KLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVH 188 Query: 182 RDLKPENLLLDANGTL---KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RD+KPEN+LL+ +L K+ DFGLS+ +D L GT Y+APEV+ K + Sbjct: 189 RDIKPENILLENKHSLLNIKIVDFGLSSF---FSKDNKLRDRLGTAYYIAPEVLRKKYNE 245 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSWFSTSAKKLIKK 520 K D+WSCGVIL++L+ GY PF N + KK+ Y DF+ S AK+LIK Sbjct: 246 --KCDVWSCGVILYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKL 303 Query: 521 ILDPNPNTRIT 553 +L + N RIT Sbjct: 304 MLTYDYNKRIT 314
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 130 bits (328), Expect = 2e-30 Identities = 62/185 (33%), Positives = 108/185 (58%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y ++Y++ME + GEL+ + R + A Y Q+ +A+DY H R + H Sbjct: 171 QLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHERNILH 230 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPEN+++ N T+K++DFG S ++ + T CGT +Y++PE+I ++ Y+ K Sbjct: 231 RDIKPENIIIGFNNTIKLTDFGWSVITP---KGSKRKTLCGTVDYLSPELIRSREYN-EK 286 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+W+ GV+ + L+ G PFE+ + YK+I K + P T A+ LI ++L+ +P Sbjct: 287 VDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDHVDTEARHLISRLLEYDPG 346 Query: 542 TRITI 556 RI + Sbjct: 347 DRIPL 351
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 130 bits (327), Expect = 2e-30 Identities = 69/179 (38%), Positives = 105/179 (58%), Gaps = 3/179 (1%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 T IY+++EL L + + R +L E + R Q++ A+ Y H + V HRDLK N++ Sbjct: 111 TNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRDLKLGNIM 170 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI-NNKGYDGAKADLWSCGV 385 LD + +K+ DFGL+AL E + T CGTPNY+APE++ N+K + DLWS GV Sbjct: 171 LDESNNVKIGDFGLAALLMDDEERKM--TICGTPNYIAPEILFNSKEGHSFEVDLWSAGV 228 Query: 386 ILFVLMAGYLPFEDSNLMALYKKIYKADFSCPS--WFSTSAKKLIKKILDPNPNTRITI 556 +++ L+ G PF+D + +Y+KI +S PS S AK LI +L +P+ R +I Sbjct: 229 VMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDPSIRPSI 287
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 130 bits (327), Expect = 2e-30 Identities = 66/176 (37%), Positives = 104/176 (59%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 ++ ++ VME V GGELF ++ ED R Y ++++A+DY HS + +RDLK EN Sbjct: 217 TKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLEN 276 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 L+LD +G +K++DFGL + + + + T CGTP Y+APEV+ + Y G D W G Sbjct: 277 LMLDKDGHIKITDFGL--CKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLG 333 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 V+++ +M G LPF + + L++ I D P S+ AK L+ +L +PN R+ Sbjct: 334 VVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRL 389
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 130 bits (327), Expect = 2e-30 Identities = 78/197 (39%), Positives = 116/197 (58%), Gaps = 14/197 (7%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV + ++VMEL+ GGELF++I + E +A ++L++AV + H GV H Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVH 542 Query: 182 RDLKPENLLL-DANGTL--KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL D N L K+ DFG + L ++ L T C T +Y APE++N GYD Sbjct: 543 RDLKPENLLFTDENDNLEIKIIDFGFARLKPP--DNQPLKTPCFTLHYAAPELLNQNGYD 600 Query: 353 GAKADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSC--PSW--FSTS 499 DLWS GVIL+ +++G +PF+ ++ + + KKI K DFS +W S Sbjct: 601 -ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQE 659 Query: 500 AKKLIKKILDPNPNTRI 550 AK LI+ +L +PN R+ Sbjct: 660 AKDLIQGLLTVDPNKRL 676 Score = 114 bits (284), Expect = 2e-25 Identities = 60/188 (31%), Positives = 112/188 (59%), Gaps = 6/188 (3%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 ++ + TK++++++ + GGELF ++ R R E + + Y +++ A+++ H G+ +R Sbjct: 117 LHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYR 176 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI--NNKGYDGA 358 D+K EN+LLD+NG + ++DFGLS E ++ CGT Y+AP+++ + G+D A Sbjct: 177 DIKLENILLDSNGHVVLTDFGLSK-EFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKA 235 Query: 359 KADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 D WS GV+++ L+ G PF E ++ + ++I K++ P S AK LI+++L Sbjct: 236 -VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLL 294 Query: 527 DPNPNTRI 550 +P R+ Sbjct: 295 MKDPKKRL 302
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 130 bits (327), Expect = 2e-30 Identities = 66/176 (37%), Positives = 104/176 (59%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 ++ ++ VME V GGELF ++ ED R Y ++++A+DY HS + +RDLK EN Sbjct: 217 TKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLEN 276 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 L+LD +G +K++DFGL + + + + T CGTP Y+APEV+ + Y G D W G Sbjct: 277 LMLDKDGHIKITDFGL--CKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLG 333 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 V+++ +M G LPF + + L++ I D P S+ AK L+ +L +PN R+ Sbjct: 334 VVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRL 389
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 130 bits (327), Expect = 2e-30 Identities = 66/176 (37%), Positives = 104/176 (59%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 ++ ++ VME V GGELF ++ ED R Y ++++A+DY HS + +RDLK EN Sbjct: 217 TKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLEN 276 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 L+LD +G +K++DFGL + + + + T CGTP Y+APEV+ + Y G D W G Sbjct: 277 LMLDKDGHIKITDFGL--CKEGITDAATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLG 333 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 V+++ +M G LPF + + L++ I D P S+ AK L+ +L +PN R+ Sbjct: 334 VVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRL 389
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 130 bits (327), Expect = 2e-30 Identities = 79/189 (41%), Positives = 107/189 (56%), Gaps = 4/189 (2%) Frame = +2 Query: 2 RMYEVM-ASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVY 178 + YE+ S +IYIVMEL G+L I RG L ED K F+Q+ +AV YCH V Sbjct: 74 KTYEIFETSDGRIYIVMELGVQGDLLTFIKCRGALHEDVGGKMFRQVSSAVKYCHDLDVV 133 Query: 179 HRDLKPENLLLDANGTLKVSDFGLS--ALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 HRDLK ENLLLD + +K+SDFG S L L T CG+ Y APEV Y Sbjct: 134 HRDLKCENLLLDKDFNIKLSDFGFSKGCLRDGSGRIVLSKTFCGSAAYAAPEVRQGIPYQ 193 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMAL-YKKIYKADFSCPSWFSTSAKKLIKKILD 529 D+WS GVIL++++ G +P++DS++ L +K ++ DF + K LI +IL Sbjct: 194 PKVYDIWSLGVILYIMVCGSMPYDDSDIKKLRIQKEHRVDFPRSKNLTGECKDLIYRILQ 253 Query: 530 PNPNTRITI 556 P+ N R+ I Sbjct: 254 PDVNRRLHI 262
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 130 bits (327), Expect = 2e-30 Identities = 67/185 (36%), Positives = 104/185 (56%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y R +IY+++E GEL+ ++ E ++L +A+ YCH + V H Sbjct: 139 RLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIH 198 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ K Sbjct: 199 RDIKPENLLLGLKGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRMHN-EK 253 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLW GV+ + L+ G PFE ++ Y++I K D P+ T A+ LI K+L NP+ Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPS 313 Query: 542 TRITI 556 R+ + Sbjct: 314 ERLPL 318
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 130 bits (326), Expect = 3e-30 Identities = 73/185 (39%), Positives = 104/185 (56%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++++ + +Y++ME GGEL+ + +G + R Y ++ A DY HSR + + Sbjct: 840 KLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIY 899 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLL+ G +K+ DFG + Q R+ T CGTP YVAPEVI N+G+D Sbjct: 900 RDLKPENLLLNERGYVKLVDFGFAKKLQTGRK---TWTFCGTPEYVAPEVILNRGHD-IS 955 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS GV++F L+ G PF S+ M Y I K P + +A LIKK+ N Sbjct: 956 ADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDN 1015 Query: 536 PNTRI 550 P R+ Sbjct: 1016 PAERL 1020
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 130 bits (326), Expect = 3e-30 Identities = 73/185 (39%), Positives = 104/185 (56%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++++ + +Y++ME GGEL+ + +G + R Y ++ A DY HSR + + Sbjct: 686 KLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIY 745 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENLLL+ G +K+ DFG + Q R+ T CGTP YVAPEVI N+G+D Sbjct: 746 RDLKPENLLLNERGYVKLVDFGFAKKLQTGRK---TWTFCGTPEYVAPEVILNRGHD-IS 801 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS GV++F L+ G PF S+ M Y I K P + +A LIKK+ N Sbjct: 802 ADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDN 861 Query: 536 PNTRI 550 P R+ Sbjct: 862 PAERL 866
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 130 bits (326), Expect = 3e-30 Identities = 67/185 (36%), Positives = 102/185 (55%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y + +IY+++E GEL+ ++ G E ++L +A+ YCH + V H Sbjct: 142 QLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSDALMYCHKKKVIH 201 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ Sbjct: 202 RDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRMHN-EM 256 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLW GV+ + LM G PFE + Y++I K D PS AK LI K+L NP+ Sbjct: 257 VDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMPLGAKDLISKLLKHNPS 316 Query: 542 TRITI 556 R+ + Sbjct: 317 QRLPL 321
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 129 bits (325), Expect = 4e-30 Identities = 66/178 (37%), Positives = 104/178 (58%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 S K+Y+V+ + GGELF + GR +R Y +L+ A+D H V +RDLKPEN Sbjct: 413 SPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPEN 472 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 +LLD G + + DFGL L+ ++++ T CGTP Y+APE++ +GY D W+ G Sbjct: 473 ILLDYQGHIALCDFGLCKLN--MKDNDKTDTFCGTPEYLAPEILLGQGYT-KTVDWWTLG 529 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRITI 556 ++L+ +M G P+ D N+ +YKKI + P F +AK L+ +L +P+ R+ + Sbjct: 530 ILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGV 587
>KCC1_METAN (O14408) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| Length = 382 Score = 129 bits (325), Expect = 4e-30 Identities = 79/184 (42%), Positives = 105/184 (57%), Gaps = 7/184 (3%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 SR K YIV +L TGGELFD+I +G+ E DA + +Q++ AVDY H V HRDLKPEN Sbjct: 88 SRDKFYIVTQLATGGELFDRICDQGKFTEVDASQTIRQIMTAVDYLHDNDVVHRDLKPEN 147 Query: 203 LLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLW 373 LL D + L ++DFG++ + ++E+ L T G+ Y APEV+ KG+ G D+W Sbjct: 148 LLYVTRDPDSDLVLADFGITK-TLDIKEE-TLTTMAGSFGYAAPEVMEQKGH-GKPVDMW 204 Query: 374 SCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDPNPN 541 S GVI + L+ GY PF NL L ++ A F W S AK I +L P P Sbjct: 205 SMGVITYTLLCGYSPFRSENLRDLLRECTAAPVPFHERYWKDVSQDAKDFILVLLVPEPE 264 Query: 542 TRIT 553 R T Sbjct: 265 KRWT 268
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 129 bits (324), Expect = 6e-30 Identities = 71/187 (37%), Positives = 106/187 (56%), Gaps = 10/187 (5%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 S + +++V +L+ GELFD + + L E + R + L+ AV + H+ + HRDLKPEN Sbjct: 99 SSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPEN 158 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI------NNKGYDGAKA 364 +LLD N +++SDFG S + L CGTP Y+APE++ + GY G + Sbjct: 159 ILLDDNMQIRLSDFGFSC---HLEAGEKLRELCGTPGYLAPEILKCSMDETHPGY-GKEV 214 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDP 532 DLW+CGVILF L+AG PF + + + I + F+ P W S + K LI K+L Sbjct: 215 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDCSNTVKDLISKLLQV 274 Query: 533 NPNTRIT 553 +P R+T Sbjct: 275 DPEARLT 281
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 129 bits (324), Expect = 6e-30 Identities = 71/187 (37%), Positives = 107/187 (57%), Gaps = 10/187 (5%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 S + +++V +L+ GELFD + + L E + R + L+ AV + H+ + HRDLKPEN Sbjct: 99 SSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPEN 158 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI------NNKGYDGAKA 364 +LLD N +++SDFG S + L CGTP Y+APE++ + GY G + Sbjct: 159 ILLDDNMQIRLSDFGFSC---HLEPGEKLRELCGTPGYLAPEILKCSMDETHPGY-GKEV 214 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDP 532 DLW+CGVILF L+AG PF + + + I + FS P W S++ K LI ++L Sbjct: 215 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQV 274 Query: 533 NPNTRIT 553 +P R+T Sbjct: 275 DPEARLT 281
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 129 bits (324), Expect = 6e-30 Identities = 65/185 (35%), Positives = 102/185 (55%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y ++Y+++E GEL+ ++ +L E ++L +A+ YCH + V H Sbjct: 105 RLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIH 164 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL G +K++DFG S + +R T CGT +Y+ PE+I + YD K Sbjct: 165 RDIKPENLLLGFRGEVKIADFGWSVHTPSLRR----KTMCGTLDYLPPEMIEGRTYD-EK 219 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLW GV+ + L+ GY PFE ++ Y++I K D P A+ LI ++L P Sbjct: 220 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISRLLRYQPL 279 Query: 542 TRITI 556 R+ + Sbjct: 280 ERLPL 284
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 129 bits (324), Expect = 6e-30 Identities = 64/186 (34%), Positives = 105/186 (56%), Gaps = 1/186 (0%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R++ + ++Y+++E V GEL+ + ++ R E A Y Q+ A+ Y H + + H Sbjct: 161 RLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKNIIH 220 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPEN+LL N T+K+SDFG S + R T CGT +Y+ PE++ ++ YD Sbjct: 221 RDIKPENILLHFNDTIKISDFGWSVHAPSNRRS----TLCGTMDYLPPEIVQSRPYD-KN 275 Query: 362 ADLWSCGVILFVLMAGYLPFED-SNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNP 538 D+WS G++++ + G PFE+ A Y++I K D P + S A LIK++L +P Sbjct: 276 VDVWSLGILMYEFLCGAPPFEEPGGAQATYRRIVKLDLRIPPYVSADAADLIKRMLTLDP 335 Query: 539 NTRITI 556 R + Sbjct: 336 AKRFKL 341
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 129 bits (323), Expect = 7e-30 Identities = 64/173 (36%), Positives = 99/173 (57%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 K+Y+++E ++GGELF + G ED A Y ++ A+ + HS G+ +RDLKPEN++L Sbjct: 143 KLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSHGIIYRDLKPENIML 202 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 + G +K++DFGL + + E + HT CGT Y+APE++ G++ A D WS G ++ Sbjct: 203 SSQGHIKLTDFGL--CKESIHEGAITHTFCGTIEYMAPEILVRTGHNRA-VDWWSLGALM 259 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + ++ G PF N KI K P + + A+ L KK L NP RI Sbjct: 260 YDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLAKKFLKRNPTQRI 312
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 128 bits (322), Expect = 9e-30 Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 8/192 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++YE Y+V ++ TGGELFD+I SR R E DA + +Q+++ + Y H V H Sbjct: 131 KLYEFFEDNNYYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKNNVVH 190 Query: 182 RDLKPENLLLDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 349 RDLKPEN+LL+ +K+ DFGLS + ++ + GT Y+AP+V++ Y Sbjct: 191 RDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVLHGT-Y 246 Query: 350 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIK 517 D K D+WSCGVIL++L++G PF SN + KK+ K F P + S AK LIK Sbjct: 247 D-EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVEAGKYTFDLPQFKKISDKAKDLIK 305 Query: 518 KILDPNPNTRIT 553 K+L RI+ Sbjct: 306 KMLMYTSAVRIS 317
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 128 bits (322), Expect = 9e-30 Identities = 74/183 (40%), Positives = 106/183 (57%), Gaps = 7/183 (3%) Frame = +2 Query: 26 RTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENL 205 ++ +++VMEL GGELFD+I ++G E A + ++N V+ CH GV HRDLKPEN Sbjct: 156 KSNVHVVMELCAGGELFDRIIAKGHYSERAAATICRAVVNVVNICHFMGVMHRDLKPENF 215 Query: 206 LL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWS 376 LL + N LK +DFGLS + E + G+ YVAPEV+ + Y G + D+WS Sbjct: 216 LLATKEENAMLKATDFGLSVF---IEEGKMYRDIVGSAYYVAPEVL-RRNY-GKEIDVWS 270 Query: 377 CGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDPNPNT 544 GVIL++L++G PF ++ I + DF W S SAK L++K+L +P Sbjct: 271 AGVILYILLSGVPPFWAETEKGIFDAILQGEIDFESQPWPSISESAKDLVRKMLTQDPKK 330 Query: 545 RIT 553 RIT Sbjct: 331 RIT 333
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 128 bits (321), Expect = 1e-29 Identities = 75/197 (38%), Positives = 115/197 (58%), Gaps = 14/197 (7%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV + ++VMEL+ GGEL ++I + E +A ++L++AV + H GV H Sbjct: 473 KLHEVYHDQLHTFLVMELLKGGELLERIQKKQHFSETEASHIMRRLVSAVSHMHDVGVVH 532 Query: 182 RDLKPENLLL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL N +K+ DFG + L ++ L T C T +Y APE+ N+ GYD Sbjct: 533 RDLKPENLLFTDETDNSEIKIIDFGFARLKPP--DNQPLKTPCFTLHYAAPELFNHNGYD 590 Query: 353 GAKADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSC--PSW--FSTS 499 DLWS GVIL+ +++G +PF+ ++ + + KKI K +FS +W S Sbjct: 591 -ESCDLWSLGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKGEFSFEGEAWKNVSEE 649 Query: 500 AKKLIKKILDPNPNTRI 550 AK+LI+ +L +PN RI Sbjct: 650 AKELIQGLLTVDPNKRI 666 Score = 111 bits (277), Expect = 2e-24 Identities = 57/180 (31%), Positives = 111/180 (61%), Gaps = 6/180 (3%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 TK++++++ + GGELF ++ R R E++ + Y +++ A+++ H G+ +RD+K EN+L Sbjct: 115 TKLHLILDYINGGELFTHLSQRERFSENEVQIYIGEIVLALEHLHKLGIIYRDIKLENIL 174 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI--NNKGYDGAKADLWSCG 382 LD++G + ++DFGLS E+ ++ CGT Y+AP+++ + G+D A D WS G Sbjct: 175 LDSDGHVVLTDFGLSK-EFLTDENERAYSFCGTIEYMAPDIVRGGDTGHDKA-VDWWSVG 232 Query: 383 VILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 V+++ L+ G PF E ++ + ++I K++ P S +K +I+++L +P R+ Sbjct: 233 VLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALSKDIIQRLLMKDPKKRL 292
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 128 bits (321), Expect = 1e-29 Identities = 77/197 (39%), Positives = 116/197 (58%), Gaps = 14/197 (7%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++EV + ++VMEL+ GGELF++I + E +A ++L++AV + H GV H Sbjct: 483 KLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVH 542 Query: 182 RDLKPENLLL-DANGTL--KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RDLKPENLL D N L K+ DFG + + ++ L T C T +Y APE++N GYD Sbjct: 543 RDLKPENLLFTDENDNLEIKIIDFGFA--RPKPPDNQPLKTPCFTLHYAAPELLNQNGYD 600 Query: 353 GAKADLWSCGVILFVLMAGYLPFED-------SNLMALYKKIYKADFSC--PSW--FSTS 499 DLWS GVIL+ +++G +PF+ ++ + + KKI K DFS +W S Sbjct: 601 -ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQE 659 Query: 500 AKKLIKKILDPNPNTRI 550 AK LI+ +L +PN R+ Sbjct: 660 AKDLIQGLLTVDPNKRL 676 Score = 113 bits (282), Expect = 4e-25 Identities = 60/188 (31%), Positives = 111/188 (59%), Gaps = 6/188 (3%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 ++ + TK++++++ + GGELF ++ R R E + + Y +++ A+++ H G+ +R Sbjct: 117 LHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYR 176 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI--NNKGYDGA 358 D+K EN+LLD+NG + ++DFGLS E ++ CGT Y+AP+++ + G+D A Sbjct: 177 DIKLENILLDSNGHVMLTDFGLSK-EFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKA 235 Query: 359 KADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 D WS GV+++ L+ G PF E ++ + ++I K++ P S AK LI+ +L Sbjct: 236 -VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQHLL 294 Query: 527 DPNPNTRI 550 +P R+ Sbjct: 295 MKDPKKRL 302
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 128 bits (321), Expect = 1e-29 Identities = 69/164 (42%), Positives = 102/164 (62%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD 214 +++VM+ GGELF + R E A+ Y ++I A+DY H + +RDLKPENLLLD Sbjct: 274 LFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLD 333 Query: 215 ANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILF 394 G LK+ DFG +++V T CGTP+Y+APE+I+ K Y+ A AD WS G+++F Sbjct: 334 RFGHLKIVDFG---FAKRVSTSNCC-TLCGTPDYLAPEIISLKPYNKA-ADWWSLGILIF 388 Query: 395 VLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++AGY PF N M LY+ I + + PS+FS ++ L+ +L Sbjct: 389 EMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLL 432
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 127 bits (320), Expect = 2e-29 Identities = 72/191 (37%), Positives = 109/191 (57%), Gaps = 7/191 (3%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++++V + Y+V E GGELF++I +R + E DA +Q+++ + Y H + H Sbjct: 128 KLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVH 187 Query: 182 RDLKPENLLLDANGTL---KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD 352 RD+KPEN+LL+ +L K+ DFGLS+ +D L GT Y+APEV+ K + Sbjct: 188 RDIKPENILLENKNSLLNIKIVDFGLSSF---FSKDYKLRDRLGTAYYIAPEVLKKKYNE 244 Query: 353 GAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKI----YKADFSCPSWFSTSAKKLIKK 520 K D+WSCGVI+++L+ GY PF N + KK+ Y DF+ S AK+LIK Sbjct: 245 --KCDVWSCGVIMYILLCGYPPFGGQNDQDIIKKVEKGKYYFDFNDWKNISDEAKELIKL 302 Query: 521 ILDPNPNTRIT 553 +L + N R T Sbjct: 303 MLTYDYNKRCT 313
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 127 bits (319), Expect = 2e-29 Identities = 68/176 (38%), Positives = 100/176 (56%) Frame = +2 Query: 23 SRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPEN 202 S K+Y V+ + GGELF + GR AR Y +L+ A+D H V +RDLKPEN Sbjct: 416 SPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPEN 475 Query: 203 LLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCG 382 +LLD G + + DFGL L+ +++D T CGTP Y+APE++ GY A D W+ G Sbjct: 476 ILLDYQGHIALCDFGLCKLN--MKDDDKTDTFCGTPEYLAPELLLGLGYTKA-VDWWTLG 532 Query: 383 VILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 V+L+ ++ G P+ D ++ +YKKI + P F AK L+ +L +P R+ Sbjct: 533 VLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRL 588
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL II)| Length = 743 Score = 127 bits (319), Expect = 2e-29 Identities = 65/182 (35%), Positives = 104/182 (57%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 ++ ++ +++ VME V GG+L +I + E AR Y ++ A+ + H G+ +R Sbjct: 467 LHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLALMFLHRHGIIYR 526 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA 364 DLK +N+LLDA G K++DFG+ + + E+ L T CGTP+Y+APE++ YD A Sbjct: 527 DLKLDNILLDAEGHCKIADFGM--CKEGMTENKLTQTFCGTPDYIAPEILQELKYD-ASV 583 Query: 365 DLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNT 544 D W+ GV+++ +MAG PFE N L++ I D P W S A ++K + NP Sbjct: 584 DWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKGFMTKNPAK 643 Query: 545 RI 550 R+ Sbjct: 644 RL 645
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 127 bits (319), Expect = 2e-29 Identities = 65/185 (35%), Positives = 104/185 (56%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +Y+++E GEL+ + + R + A Y Q+ A+DY H++ + H Sbjct: 210 RLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTKHIIH 269 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPEN+LL + +K+SDFG S S L T CGT +Y+ PE+I + +D Sbjct: 270 RDIKPENILLSTDNCIKLSDFGWSVKSLPSSSTKRL-TICGTLDYLPPEMIESNEHD-YT 327 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+WS G++ + + G PFE+ + + YK+I K D PS+ S+ A LI ++L +P Sbjct: 328 VDIWSLGILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEATDLILRLLQKSPK 387 Query: 542 TRITI 556 RIT+ Sbjct: 388 KRITL 392
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 127 bits (318), Expect = 3e-29 Identities = 66/179 (36%), Positives = 105/179 (58%), Gaps = 6/179 (3%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 K+Y +++ V GGELF + + ED R Y +++ A+++ H GV +RDLKPENLLL Sbjct: 192 KLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLL 251 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTT------CGTPNYVAPEVINNKGYDGAKADLW 373 G + ++DFGL ++GLL T CGTP Y+APEV+ GY G + D W Sbjct: 252 TNEGHICMTDFGLC-------KEGLLTPTDKTGTFCGTPEYLAPEVLQGNGY-GKQVDWW 303 Query: 374 SCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 S G +L+ ++ G PF + ++ +Y+KI S P + S A+ L++++L+ +P R+ Sbjct: 304 SFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPEKRL 362
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 126 bits (317), Expect = 4e-29 Identities = 64/173 (36%), Positives = 101/173 (58%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 ++ VME GGELF ++ ED AR Y ++++A++Y HSR V +RD+K ENL+L Sbjct: 229 RLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLML 288 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 D +G +K++DFGL + + + + T CGTP Y+APEV+ + Y G D W GV++ Sbjct: 289 DKDGHVKITDFGL--CKEGITDGATMRTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVM 345 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + +M G LPF + + L++ I + P S AK L+ +L +P R+ Sbjct: 346 YEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRL 398
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 126 bits (317), Expect = 4e-29 Identities = 75/192 (39%), Positives = 110/192 (57%), Gaps = 8/192 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++YE Y+V ++ +GGELFD+I SR R E DA + +Q+++ + Y H V H Sbjct: 131 KLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVH 190 Query: 182 RDLKPENLLLDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 349 RDLKPEN+LL+ +K+ DFGLS + ++ + GT Y+AP+V++ Y Sbjct: 191 RDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVLHGT-Y 246 Query: 350 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIK 517 D K D+WSCGVIL++L++G PF SN + KK+ K F P + S AK LIK Sbjct: 247 D-EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIK 305 Query: 518 KILDPNPNTRIT 553 K+L RI+ Sbjct: 306 KMLMYTSAVRIS 317
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 126 bits (317), Expect = 4e-29 Identities = 75/192 (39%), Positives = 110/192 (57%), Gaps = 8/192 (4%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++YE Y+V ++ +GGELFD+I SR R E DA + +Q+++ + Y H V H Sbjct: 131 KLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNVVH 190 Query: 182 RDLKPENLLLDANG----TLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGY 349 RDLKPEN+LL+ +K+ DFGLS + ++ + GT Y+AP+V++ Y Sbjct: 191 RDLKPENILLETKNKEDMIIKIIDFGLSTHFEYSKK---MKDKIGTAYYIAPDVLHGT-Y 246 Query: 350 DGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIK 517 D K D+WSCGVIL++L++G PF SN + KK+ K F P + S AK LIK Sbjct: 247 D-EKCDIWSCGVILYILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAKDLIK 305 Query: 518 KILDPNPNTRIT 553 K+L RI+ Sbjct: 306 KMLMYTSAVRIS 317
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 126 bits (316), Expect = 5e-29 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +Y++ME GGEL+ + RG ++ R Y ++ A Y HS+G+ + Sbjct: 422 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIY 481 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL+LD G K+ DFG ++++ T CGTP YVAPE+I NKG+D Sbjct: 482 RDLKPENLILDHRGYAKLVDFG---FAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD-IS 537 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS G++++ L+ G PF + M Y I + P + +A LIKK+ N Sbjct: 538 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN 597 Query: 536 PNTRI 550 P+ R+ Sbjct: 598 PSERL 602
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 126 bits (316), Expect = 5e-29 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +Y++ME GGEL+ + RG ++ R Y ++ A Y HS+G+ + Sbjct: 422 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIY 481 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL+LD G K+ DFG ++++ T CGTP YVAPE+I NKG+D Sbjct: 482 RDLKPENLILDHRGYAKLVDFG---FAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD-IS 537 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS G++++ L+ G PF + M Y I + P + +A LIKK+ N Sbjct: 538 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN 597 Query: 536 PNTRI 550 P+ R+ Sbjct: 598 PSERL 602
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 126 bits (316), Expect = 5e-29 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +Y++ME GGEL+ + RG ++ R Y ++ A Y HS+G+ + Sbjct: 422 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIY 481 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL+LD G K+ DFG ++++ T CGTP YVAPE+I NKG+D Sbjct: 482 RDLKPENLILDHRGYAKLVDFG---FAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD-IS 537 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS G++++ L+ G PF + M Y I + P + +A LIKK+ N Sbjct: 538 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN 597 Query: 536 PNTRI 550 P+ R+ Sbjct: 598 PSERL 602
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 126 bits (316), Expect = 5e-29 Identities = 76/189 (40%), Positives = 116/189 (61%), Gaps = 4/189 (2%) Frame = +2 Query: 2 RMYEVMASRT-KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVY 178 ++YE++ S KI +VMEL GG++FD + + G L E A+ F+Q++ A+ YCH GV Sbjct: 72 QVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVA 131 Query: 179 HRDLKPENLLLDANGTLKVSDFGLS-ALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDG 355 HRDLK EN LL LK++DFG + L + RE L T CG+ Y APEV+ +D Sbjct: 132 HRDLKCENALLQ-GFNLKLTDFGFAKVLPKSHRE--LSQTFCGSTAYAAPEVLQGIPHDS 188 Query: 356 AKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSA--KKLIKKILD 529 K D+WS GV+L+V++ LPF+D+++ + + K S P+ S SA + L+K++L+ Sbjct: 189 KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKG-VSFPTHLSISADCQDLLKRLLE 247 Query: 530 PNPNTRITI 556 P+ R +I Sbjct: 248 PDMILRPSI 256
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 126 bits (316), Expect = 5e-29 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +Y++ME GGEL+ + RG ++ R Y ++ A Y HS+G+ + Sbjct: 438 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIY 497 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL+LD G K+ DFG ++++ T CGTP YVAPE+I NKG+D Sbjct: 498 RDLKPENLILDHRGYAKLVDFG---FAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD-IS 553 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS G++++ L+ G PF + M Y I + P + +A LIKK+ N Sbjct: 554 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN 613 Query: 536 PNTRI 550 P+ R+ Sbjct: 614 PSERL 618
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 126 bits (316), Expect = 5e-29 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +Y++ME GGEL+ + RG ++ R Y ++ A Y HS+G+ + Sbjct: 438 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIY 497 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL+LD G K+ DFG ++++ T CGTP YVAPE+I NKG+D Sbjct: 498 RDLKPENLILDHRGYAKLVDFG---FAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD-IS 553 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS G++++ L+ G PF + M Y I + P + +A LIKK+ N Sbjct: 554 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN 613 Query: 536 PNTRI 550 P+ R+ Sbjct: 614 PSERL 618
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 126 bits (316), Expect = 5e-29 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 2/185 (1%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 R+Y +Y++ME GGEL+ + RG ++ R Y ++ A Y HS+G+ + Sbjct: 438 RLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIY 497 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL+LD G K+ DFG ++++ T CGTP YVAPE+I NKG+D Sbjct: 498 RDLKPENLILDHRGYAKLVDFG---FAKKIGFGKKTWTFCGTPEYVAPEIILNKGHD-IS 553 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSWFSTSAKKLIKKILDPN 535 AD WS G++++ L+ G PF + M Y I + P + +A LIKK+ N Sbjct: 554 ADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDN 613 Query: 536 PNTRI 550 P+ R+ Sbjct: 614 PSERL 618
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 125 bits (315), Expect = 6e-29 Identities = 69/183 (37%), Positives = 104/183 (56%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +MY + +Y++ E + GGELF + + AR Y +++ A+ Y HS+ + + Sbjct: 91 KMYCASWDKYNLYMLFEYLAGGELFSYLRASRTFSNSMARFYAAEIVCALQYLHSKNIAY 150 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPENL+L+ G LK++DFG +++V + T CGTP Y+APEVI NKG+D A Sbjct: 151 RDLKPENLMLNKEGHLKMTDFG---FAKEVID--RTWTMCGTPEYLAPEVIGNKGHDTA- 204 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D WS GV+++ +M G PF L +Y+KI F AK L+KK+L + Sbjct: 205 VDWWSLGVLIYEMMIGIPPFRGKTLDEIYEKIILGKLRFTRSFDLFAKDLVKKLLQVDRT 264 Query: 542 TRI 550 R+ Sbjct: 265 QRL 267
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 125 bits (315), Expect = 6e-29 Identities = 64/173 (36%), Positives = 101/173 (58%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 ++ VME GGELF ++ ED AR Y ++++A++Y HSR V +RD+K ENL+L Sbjct: 228 RLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLML 287 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 D +G +K++DFGL + + + + T CGTP Y+APEV+ + Y G D W GV++ Sbjct: 288 DKDGHVKITDFGL--CKEGITDGATMRTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVM 344 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + +M G LPF + + L++ I + P S AK L+ +L +P R+ Sbjct: 345 YEMMCGRLPFYNQDHERLFELILMEETRFPRTLSPEAKSLLAGLLKKDPKQRL 397
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 125 bits (314), Expect = 8e-29 Identities = 68/183 (37%), Positives = 108/183 (59%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y K+ ++ME V GGELF + GR E AR Y ++I+A+ + H RG+ + Sbjct: 71 KLYSTDFHGGKVGLIMEYVGGGELFYWLKKCGRFDEQMARFYAAEIISALRFIHGRGILY 130 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RDLKPEN+L+ + G +K+ DFG S V E ++ GTP Y++PE + ++ DG Sbjct: 131 RDLKPENILITSTGHIKLIDFGFS-----VYESENIYMISGTPEYMSPEKLRSED-DGRA 184 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 +D W GV+++ ++ G PF DS+ A+Y KI +++ P + S A+ LI +LD N Sbjct: 185 SDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHYVSPVARCLITGLLDKNRA 244 Query: 542 TRI 550 TR+ Sbjct: 245 TRL 247
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 125 bits (314), Expect = 8e-29 Identities = 60/173 (34%), Positives = 103/173 (59%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 K+Y+++E ++GGELF ++ G ED A Y ++ A+ + H +G+ +RDLKPEN++L Sbjct: 167 KLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIML 226 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 + G +K++DFGL + + + + HT CGT Y+APE++ G++ A D WS G ++ Sbjct: 227 NHQGHVKLTDFGL--CKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA-VDWWSLGALM 283 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + ++ G PF N KI K + P + + A+ L+KK+L N +R+ Sbjct: 284 YDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRL 336
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 125 bits (314), Expect = 8e-29 Identities = 60/173 (34%), Positives = 103/173 (59%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 K+Y+++E ++GGELF ++ G ED A Y ++ A+ + H +G+ +RDLKPEN++L Sbjct: 167 KLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIML 226 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 + G +K++DFGL + + + + HT CGT Y+APE++ G++ A D WS G ++ Sbjct: 227 NHQGHVKLTDFGL--CKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA-VDWWSLGALM 283 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + ++ G PF N KI K + P + + A+ L+KK+L N +R+ Sbjct: 284 YDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRL 336
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 125 bits (314), Expect = 8e-29 Identities = 60/173 (34%), Positives = 103/173 (59%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 K+Y+++E ++GGELF ++ G ED A Y ++ A+ + H +G+ +RDLKPEN++L Sbjct: 167 KLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIML 226 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 + G +K++DFGL + + + + HT CGT Y+APE++ G++ A D WS G ++ Sbjct: 227 NHQGHVKLTDFGL--CKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA-VDWWSLGALM 283 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + ++ G PF N KI K + P + + A+ L+KK+L N +R+ Sbjct: 284 YDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRL 336
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 125 bits (314), Expect = 8e-29 Identities = 60/173 (34%), Positives = 103/173 (59%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 K+Y+++E ++GGELF ++ G ED A Y ++ A+ + H +G+ +RDLKPEN++L Sbjct: 167 KLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIML 226 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 + G +K++DFGL + + + + HT CGT Y+APE++ G++ A D WS G ++ Sbjct: 227 NHQGHVKLTDFGL--CKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRA-VDWWSLGALM 283 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + ++ G PF N KI K + P + + A+ L+KK+L N +R+ Sbjct: 284 YDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRL 336
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 125 bits (314), Expect = 8e-29 Identities = 61/166 (36%), Positives = 102/166 (61%) Frame = +2 Query: 29 TKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLL 208 + +Y++ + V GGELF + + G+ + Y ++++A++Y HS + +RDLKPENLL Sbjct: 345 SNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLL 404 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 ++ +G LK++DFG ++++R+ T CGTP Y+APE+I +KG++ A D W+ GV+ Sbjct: 405 INRDGHLKITDFG---FAKKLRD--RTWTLCGTPEYIAPEIIQSKGHNKA-VDWWALGVL 458 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 ++ ++ GY PF D +Y+KI AK LIKK+L Sbjct: 459 IYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLL 504
>CDPK2_MAIZE (P49101) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (CDPK 2)| Length = 513 Score = 125 bits (314), Expect = 8e-29 Identities = 73/183 (39%), Positives = 106/183 (57%), Gaps = 7/183 (3%) Frame = +2 Query: 26 RTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENL 205 ++ +++VMEL GGELFD+I ++G E A + ++N V+ CH GV HRDLKPEN Sbjct: 136 KSNVHVVMELCAGGELFDRIIAKGHYTERAAATICRAVVNVVNICHFMGVMHRDLKPENF 195 Query: 206 LL---DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWS 376 LL + N LK +DFGLS + E + G+ YVAPEV+ + Y G + D+WS Sbjct: 196 LLATMEENAMLKATDFGLSVF---IEEGKMYRDIVGSAYYVAPEVL-RRSY-GKEIDVWS 250 Query: 377 CGVILFVLMAGYLPFEDSNLMALYKKIY--KADFSCPSW--FSTSAKKLIKKILDPNPNT 544 GVIL++L++G PF ++ I + DF W S SAK L++K+L +P Sbjct: 251 AGVILYILLSGVPPFWAEIEKGIFDAILHEEIDFESQPWPSISESAKDLVRKMLTRDPKK 310 Query: 545 RIT 553 R+T Sbjct: 311 RLT 313
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 124 bits (312), Expect = 1e-28 Identities = 65/185 (35%), Positives = 101/185 (54%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y + +IY+++E GEL+ ++ E ++L +A+ YCH + V H Sbjct: 144 QLYNYFYDQQRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELSDALTYCHKKKVIH 203 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPENLLL G LK++DFG S + +R T CGT +Y+ PE+I + ++ Sbjct: 204 RDIKPENLLLGLQGELKIADFGWSVHAPSLRR----KTMCGTLDYLPPEMIEGRMHN-EM 258 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 DLW GV+ + LM G PFE + Y++I K D PS + A+ LI K+L NP Sbjct: 259 VDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVPSGAQDLISKLLKHNPW 318 Query: 542 TRITI 556 R+ + Sbjct: 319 QRLPL 323
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 124 bits (312), Expect = 1e-28 Identities = 63/173 (36%), Positives = 100/173 (57%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 ++ VME GGELF ++ ED AR Y ++++A++Y HSR V +RD+K ENL+L Sbjct: 224 RLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDIKLENLML 283 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 D +G +K++DFGL + + + + T CGTP Y+APEV+ + Y G D W GV++ Sbjct: 284 DKDGHIKITDFGL--CKEGISDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVM 340 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + +M G LPF + + L++ I + P AK L+ +L +P R+ Sbjct: 341 YEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRL 393
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 124 bits (312), Expect = 1e-28 Identities = 63/173 (36%), Positives = 101/173 (58%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL 211 ++ VME GGELF ++ E+ AR Y ++++A++Y HSR V +RD+K ENL+L Sbjct: 224 RLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLML 283 Query: 212 DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 D +G +K++DFGL + + + + T CGTP Y+APEV+ + Y G D W GV++ Sbjct: 284 DKDGHIKITDFGL--CKEGISDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVM 340 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 + +M G LPF + + L++ I + P S AK L+ +L +P R+ Sbjct: 341 YEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRL 393
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 124 bits (312), Expect = 1e-28 Identities = 71/175 (40%), Positives = 100/175 (57%), Gaps = 1/175 (0%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD 214 +Y+V+EL L + R + E +AR Y +Q I+ Y HS V HRDLK NL L+ Sbjct: 117 VYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTISGCQYLHSNRVIHRDLKLGNLFLN 176 Query: 215 ANGTLKVSDFGLSALSQQVREDG-LLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVIL 391 +K+ DFGL+ +V DG T CGTPNY+APEV+ KG+ + D+WS G I+ Sbjct: 177 DEMEVKIGDFGLAT---KVEYDGERKKTLCGTPNYIAPEVLGKKGH-SFEVDIWSIGCIM 232 Query: 392 FVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRITI 556 + L+ G PFE S L Y +I K ++S P + A LI+K+L +P +R TI Sbjct: 233 YTLLVGKPPFETSCLKETYMRIKKNEYSIPKHINPVAAALIQKMLRSDPTSRPTI 287
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 124 bits (312), Expect = 1e-28 Identities = 71/180 (39%), Positives = 103/180 (57%), Gaps = 7/180 (3%) Frame = +2 Query: 35 IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL- 211 +++VME GGELFD+I RG E A + + ++ V+ CHS GV HRDLKPEN L Sbjct: 224 VHLVMECCAGGELFDRIIQRGHYTERKAAELTRTIVGVVEACHSLGVMHRDLKPENFLFV 283 Query: 212 --DANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGV 385 + LK DFGLS + D + G+P YVAPEV+ + G +AD+WS GV Sbjct: 284 SKHEDSLLKTIDFGLSMF---FKPDDVFTDVVGSPYYVAPEVLRKR--YGPEADVWSAGV 338 Query: 386 ILFVLMAGYLPFEDSNLMALYKKIYKA--DFSCPSW--FSTSAKKLIKKILDPNPNTRIT 553 I+++L++G PF +++++ DFS W S SAK L++K+L +P R+T Sbjct: 339 IVYILLSGVPPFWAETEQGIFEQVLHGDLDFSSDPWPSISESAKDLVRKMLVRDPKKRLT 398
>PLK1_CAEEL (P34331) Serine/threonine-protein kinase plk-1 (EC 2.7.11.21)| (Polo-like kinase 1) Length = 649 Score = 124 bits (311), Expect = 2e-28 Identities = 65/184 (35%), Positives = 101/184 (54%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 +++ +YI +EL L + R + E +AR + Q+++ V Y H + H Sbjct: 101 KLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNIIH 160 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+K NL L+ + +K+ DFGL+ V D T CGTPNY+APEV+N G+ + Sbjct: 161 RDMKLGNLFLNDDLVVKIGDFGLATT---VNGDERKKTLCGTPNYIAPEVLNKAGHS-FE 216 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D+W+ G IL++L+ G PFE +L Y +I +++ PS + A LI+K+LDP P Sbjct: 217 VDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPT 276 Query: 542 TRIT 553 R T Sbjct: 277 RRPT 280
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 124 bits (311), Expect = 2e-28 Identities = 62/185 (33%), Positives = 102/185 (55%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 + Y ++Y++ME + GE++ + G + A Y Q+ NA+DY H + + H Sbjct: 166 KSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIH 225 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAK 361 RD+KPEN+L+ N +K++DFG S ++ + T CGT +Y++PE++ ++ YD Sbjct: 226 RDIKPENILIGFNNVIKLTDFGWSIINP---PENRRKTVCGTIDYLSPEMVESREYDHT- 281 Query: 362 ADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPN 541 D W+ GV+ F L+ G PFE+ YK+I D PS S A+ LI K+L +P Sbjct: 282 IDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPK 341 Query: 542 TRITI 556 R+ + Sbjct: 342 DRMRL 346
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 124 bits (311), Expect = 2e-28 Identities = 76/185 (41%), Positives = 110/185 (59%), Gaps = 14/185 (7%) Frame = +2 Query: 38 YIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLL-D 214 ++VMEL+ GGELF++I + E +A ++L++AV + H GV HRDLKPENLL D Sbjct: 559 FLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTD 618 Query: 215 ANGTL--KVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 N L KV DFG + L ++ L T C T +Y APE++ + GYD DLWS GVI Sbjct: 619 ENDNLEIKVIDFGFARLKPP--DNQPLKTPCFTLHYAAPELLTHNGYD-ESCDLWSLGVI 675 Query: 389 LFVLMAGYLPFED-------SNLMALYKKIYKADFSC--PSW--FSTSAKKLIKKILDPN 535 L+ +++G +PF+ ++ + + KKI K DFS +W S AK LI+ +L + Sbjct: 676 LYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVD 735 Query: 536 PNTRI 550 PN R+ Sbjct: 736 PNKRL 740 Score = 115 bits (287), Expect = 1e-25 Identities = 60/188 (31%), Positives = 113/188 (60%), Gaps = 6/188 (3%) Frame = +2 Query: 5 MYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYHR 184 ++ + TK++++++ + GGELF ++ R R E + + Y +++ A+++ H G+ +R Sbjct: 116 LHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYR 175 Query: 185 DLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVI--NNKGYDGA 358 D+K EN+LLD+NG + ++DFGLS E ++ CGT Y+AP+++ + G+D A Sbjct: 176 DIKLENILLDSNGHVVLTDFGLSK-EFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKA 234 Query: 359 KADLWSCGVILFVLMAGYLPF----EDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 D WS GV+++ L+ G PF E ++ + ++I K++ P ST AK L++++L Sbjct: 235 -VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLL 293 Query: 527 DPNPNTRI 550 +P R+ Sbjct: 294 MKDPKKRL 301
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 124 bits (311), Expect = 2e-28 Identities = 64/174 (36%), Positives = 102/174 (58%), Gaps = 1/174 (0%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHS-RGVYHRDLKPENLL 208 ++ VME GGELF ++ ED AR Y ++++A+DY HS + V +RDLK ENL+ Sbjct: 222 RLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLM 281 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 LD +G +K++DFGL + +++ + T CGTP Y+APEV+ + Y G D W GV+ Sbjct: 282 LDKDGHIKITDFGLC--KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVV 338 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 ++ +M G LPF + + L++ I + + P AK L+ +L +P R+ Sbjct: 339 MYEMMCGRLPFYNQDHEKLFELILMEEIAFPRTLGPEAKSLLSGLLKKDPTQRL 392
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 124 bits (311), Expect = 2e-28 Identities = 65/174 (37%), Positives = 102/174 (58%), Gaps = 1/174 (0%) Frame = +2 Query: 32 KIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHS-RGVYHRDLKPENLL 208 ++ VME GGELF ++ ED AR Y ++++A+DY HS + V +RDLK ENL+ Sbjct: 222 RLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKEVVYRDLKLENLM 281 Query: 209 LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVI 388 LD +G +K++DFGL + +++ + T CGTP Y+APEV+ + Y G D W GV+ Sbjct: 282 LDKDGHIKITDFGLC--KEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVV 338 Query: 389 LFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKILDPNPNTRI 550 ++ +M G LPF + + L++ I + P S AK L+ +L +P R+ Sbjct: 339 MYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRL 392
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)| Length = 737 Score = 124 bits (310), Expect = 2e-28 Identities = 65/188 (34%), Positives = 107/188 (56%), Gaps = 5/188 (2%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y ++ +++ VME V GG+L +I + E +R Y ++ +A+ + H GV + Sbjct: 471 QLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIY 530 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLH-----TTCGTPNYVAPEVINNKG 346 RDLK +N+LLDA G K++DFG+ ++G+L+ T CGTP+Y+APE++ Sbjct: 531 RDLKLDNILLDAEGHCKLADFGMC-------KEGILNGVTTTTFCGTPDYIAPEILQELE 583 Query: 347 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 Y G D W+ GV+++ +MAG PFE N L++ I D P W S A ++K + Sbjct: 584 Y-GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFM 642 Query: 527 DPNPNTRI 550 NP+ R+ Sbjct: 643 TKNPHKRL 650
>MAPK2_DROME (P49071) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) Length = 359 Score = 124 bits (310), Expect = 2e-28 Identities = 74/190 (38%), Positives = 110/190 (57%), Gaps = 13/190 (6%) Frame = +2 Query: 26 RTKIYIVMELVTGGELFDKIASR--GRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPE 199 R + +VME + GGELF +I + G E +A + ++ AVDY HSR + HRDLKPE Sbjct: 87 RKCLLVVMECMEGGELFQRIQDKADGAFTEREAAQIMHEICAAVDYLHSRDIAHRDLKPE 146 Query: 200 NLL---LDANGTLKVSDFGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADL 370 NLL N TLK++DFG +++ L T C TP YVAPEV+ + YD D+ Sbjct: 147 NLLYTTTQPNATLKLTDFG---FAKETFTSYTLQTPCYTPYYVAPEVLGPEKYD-KSCDI 202 Query: 371 WSCGVILFVLMAGYLPFEDSNLMALYK------KIYKADFSCPSW--FSTSAKKLIKKIL 526 WS GV+++++M G+ PF ++ +A+ + + DF P W S +AK LIK +L Sbjct: 203 WSLGVVMYIIMCGFPPFYSNHGLAISPGMKNRIRTGQYDFPDPEWTNVSQAAKDLIKGML 262 Query: 527 DPNPNTRITI 556 + +P+ R+ I Sbjct: 263 NVDPSKRLRI 272
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)| Length = 736 Score = 124 bits (310), Expect = 2e-28 Identities = 65/188 (34%), Positives = 107/188 (56%), Gaps = 5/188 (2%) Frame = +2 Query: 2 RMYEVMASRTKIYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRGVYH 181 ++Y ++ +++ VME V GG+L +I + E +R Y ++ +A+ + H GV + Sbjct: 470 QLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIY 529 Query: 182 RDLKPENLLLDANGTLKVSDFGLSALSQQVREDGLLH-----TTCGTPNYVAPEVINNKG 346 RDLK +N+LLDA G K++DFG+ ++G+L+ T CGTP+Y+APE++ Sbjct: 530 RDLKLDNILLDAEGHCKLADFGMC-------KEGILNGVTTTTFCGTPDYIAPEILQELE 582 Query: 347 YDGAKADLWSCGVILFVLMAGYLPFEDSNLMALYKKIYKADFSCPSWFSTSAKKLIKKIL 526 Y G D W+ GV+++ +MAG PFE N L++ I D P W S A ++K + Sbjct: 583 Y-GPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFM 641 Query: 527 DPNPNTRI 550 NP+ R+ Sbjct: 642 TKNPHKRL 649 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,157,498 Number of Sequences: 219361 Number of extensions: 1531526 Number of successful extensions: 8749 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6228 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6515 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4528412720 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
