ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags25d16 |
|---|---|
| Clone Library Name | barley_pub |
>MPCP_BOVIN (P12234) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 235 bits (599), Expect = 7e-62 Identities = 112/178 (62%), Positives = 129/178 (72%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 A+ PLDLVKC MQVDP KY+ I +GF V L+E G G KGW T +GYS QG CKFGFY Sbjct: 82 ALVPLDLVKCRMQVDPQKYKSIFNGFSVTLKEDGFRGLAKGWAPTFIGYSLQGLCKFGFY 141 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E FK YS++ G ENA +T +YLAASASAE AD+AL PMEA KVRIQTQPG+A L Sbjct: 142 EVFKVLYSNMLGEENAYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR 201 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCSK 538 D PK+ + EG YKG+ PLW RQIPYTMMKFACFE VE +YK VPKP+ +CSK Sbjct: 202 DAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSK 259 Score = 30.8 bits (68), Expect = 2.5 Identities = 29/144 (20%), Positives = 56/144 (38%), Gaps = 4/144 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKG----WMATLVGYSSQGAC 169 +A+ P++ K +Q P + + +E+GL F+KG WM + + AC Sbjct: 178 IALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGF 349 E K E + + V+ A A V + P ++V + + G Sbjct: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKG- 296 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGI 421 ++++ G G++KG+ Sbjct: 297 -----SSASEVLKRLGFRGVWKGL 315
>MPCP_RAT (P16036) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 356 Score = 234 bits (598), Expect = 9e-62 Identities = 110/178 (61%), Positives = 131/178 (73%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 AV PLDLVKC MQVDP KY+ I +GF + L+E G+ G KGW TL+GYS QG CKFGFY Sbjct: 76 AVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFY 135 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E FK YS+I G EN +T +YLAASASAE AD+AL PMEA KVRIQTQPG+A L Sbjct: 136 EVFKALYSNILGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR 195 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCSK 538 + +PK+ + EG YKG+ P+W RQIPYTMMKFACFE VE +YK VPKP+ +C+K Sbjct: 196 EAVPKMYKEEGLNAFYKGVAPVWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTK 253 Score = 30.8 bits (68), Expect = 2.5 Identities = 29/144 (20%), Positives = 55/144 (38%), Gaps = 4/144 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKG----WMATLVGYSSQGAC 169 +A+ P++ K +Q P + + +E+GL F+KG WM + + AC Sbjct: 172 IALAPMEAAKVRIQTQPGYANTLREAVPKMYKEEGLNAFYKGVAPVWMRQIPYTMMKFAC 231 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGF 349 E K E + V+ A A V + P ++V + + G Sbjct: 232 FERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKG- 290 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGI 421 ++++ G G++KG+ Sbjct: 291 -----STASQVLQRLGFRGVWKGL 309
>MPCP_MOUSE (Q8VEM8) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 357 Score = 234 bits (598), Expect = 9e-62 Identities = 110/178 (61%), Positives = 131/178 (73%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 AV PLDLVKC MQVDP KY+ I +GF + L+E G+ G KGW TL+GYS QG CKFGFY Sbjct: 77 AVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFY 136 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E FK YS+I G EN +T +YLA+SASAE AD+AL PMEA KVRIQTQPG+A L Sbjct: 137 EVFKALYSNILGEENTYLWRTSLYLASSASAEFFADIALAPMEAAKVRIQTQPGYANTLR 196 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCSK 538 + +PK+ + EG YKG+ PLW RQIPYTMMKFACFE VE +YK VPKP+ +C+K Sbjct: 197 EAVPKMYKEEGLNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTK 254 Score = 30.8 bits (68), Expect = 2.5 Identities = 29/144 (20%), Positives = 55/144 (38%), Gaps = 4/144 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKG----WMATLVGYSSQGAC 169 +A+ P++ K +Q P + + +E+GL F+KG WM + + AC Sbjct: 173 IALAPMEAAKVRIQTQPGYANTLREAVPKMYKEEGLNAFYKGVAPLWMRQIPYTMMKFAC 232 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGF 349 E K E + V+ A A V + P ++V + + G Sbjct: 233 FERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKG- 291 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGI 421 ++++ G G++KG+ Sbjct: 292 -----STASQVLQRLGFRGVWKGL 310
>MPCP_HUMAN (Q00325) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 233 bits (594), Expect = 3e-61 Identities = 111/178 (62%), Positives = 129/178 (72%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 A+ PLDLVKC MQVDP KY+ I +GF V L+E G+ G KGW T +GYS QG CKFGFY Sbjct: 82 ALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFY 141 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E FK YS++ G EN +T +YLAASASAE AD+AL PMEA KVRIQTQPG+A L Sbjct: 142 EVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR 201 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCSK 538 D PK+ + EG YKG+ PLW RQIPYTMMKFACFE VE +YK VPKP+ +CSK Sbjct: 202 DAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSK 259 Score = 31.6 bits (70), Expect = 1.5 Identities = 30/144 (20%), Positives = 57/144 (39%), Gaps = 4/144 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKG----WMATLVGYSSQGAC 169 +A+ P++ K +Q P + + +E+GL F+KG WM + + AC Sbjct: 178 IALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 237 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGF 349 E K E + + V+ A A V + P ++V + + G Sbjct: 238 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS 297 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGI 421 + L +++ G G++KG+ Sbjct: 298 SASL------VLKRLGFKGVWKGL 315
>MPCP_CAEEL (P40614) Phosphate carrier protein, mitochondrial precursor (PTP)| Length = 340 Score = 212 bits (539), Expect = 6e-55 Identities = 102/178 (57%), Positives = 125/178 (70%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 A+ PLDLVKC +QV+P KY I++GF + E+G KGW TL+GYS+QG KFGFY Sbjct: 60 AIVPLDLVKCRIQVNPEKYTGIATGFRTTIAEEGARALVKGWAPTLLGYSAQGLGKFGFY 119 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E FK Y+D+ G ENA +T +YLAASASAE AD+ L PMEA KVRIQT PG L Sbjct: 120 EIFKNVYADMLGEENAYLYRTSLYLAASASAEFFADILLAPMEATKVRIQTSPGAPPTLR 179 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCSK 538 P + ++EG G YKG+ PLW RQIPYTMMKFACFE VE +Y++ VPKP+ +CSK Sbjct: 180 GCAPMIYKAEGLTGFYKGLPPLWMRQIPYTMMKFACFEKTVEALYQYVVPKPRAECSK 237 Score = 32.3 bits (72), Expect = 0.86 Identities = 32/149 (21%), Positives = 61/149 (40%), Gaps = 7/149 (4%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKG----WMATLVGYSSQGAC 169 + + P++ K +Q P + ++ + +GL GF+KG WM + + AC Sbjct: 156 ILLAPMEATKVRIQTSPGAPPTLRGCAPMIYKAEGLTGFYKGLPPLWMRQIPYTMMKFAC 215 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKT---VIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 F + + Y + A+ K V+ A A V + P + V ++ Sbjct: 216 ---FEKTVEALYQYVVPKPRAECSKAEQLVVTFVAGYIAGVFCAIVSHPADTVVSKLNQD 272 Query: 341 PGFARCLTDGLPKLVRSEGAFGLYKGIVP 427 ++ G+ K + G G++KG+VP Sbjct: 273 ---SQATAGGILKKL---GFAGVWKGLVP 295 Score = 32.0 bits (71), Expect = 1.1 Identities = 23/72 (31%), Positives = 31/72 (43%) Frame = +2 Query: 284 IADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMK 463 I A+ P++ VK RIQ P + G + EGA L KG P + K Sbjct: 56 ITHTAIVPLDLVKCRIQVNPEKYTGIATGFRTTIAEEGARALVKGWAPTLLGYSAQGLGK 115 Query: 464 FACFETIVEMVY 499 F +E I + VY Sbjct: 116 FGFYE-IFKNVY 126
>MPCP_CHOFU (O61703) Phosphate carrier protein, mitochondrial precursor| (Phosphate transport protein) (PTP) Length = 349 Score = 201 bits (510), Expect = 1e-51 Identities = 99/179 (55%), Positives = 125/179 (69%), Gaps = 1/179 (0%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 AV PLDLVKC +QVD KY+++ +GF V ++E+GL G KGW T +GYS QG CKFG Y Sbjct: 66 AVVPLDLVKCRLQVDADKYKNVVNGFRVSVREEGLRGLAKGWAPTFIGYSLQGLCKFGLY 125 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E FK Y+++ E A +T +YLAASASAE AD+AL P+EA KVRIQT PG + Sbjct: 126 EVFKVQYNNMLDEETAYTYRTFVYLAASASAEFFADIALSPLEAAKVRIQTMPGVRQHTA 185 Query: 365 DGLPKLVRSEGAFG-LYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCSK 538 + + GA+ + +VPLWGRQIPYTMMKFACFE VE++YKH VPKP+ +CSK Sbjct: 186 RRVAQDGPERGAWARSTRALVPLWGRQIPYTMMKFACFEKTVELLYKHVVPKPRAECSK 244
>PIC2_YEAST (P40035) Mitochondrial phosphate carrier protein 2 (Phosphate| transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2) Length = 300 Score = 152 bits (385), Expect = 4e-37 Identities = 84/177 (47%), Positives = 107/177 (60%), Gaps = 2/177 (1%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 ++ PLDLVKC +QV+P Y GF ++ +G + G+ AT VGYS QGA K+G Y Sbjct: 35 SITPLDLVKCRLQVNPKLYTSNLQGFRKIIANEGWKKVYTGFGATFVGYSLQGAGKYGGY 94 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ-TQPGFARCL 361 EYFK YS P +YL ASA+AE +AD+ LCP EA+KV+ Q T P F + Sbjct: 95 EYFKHLYSSWLSP------GVTVYLMASATAEFLADIMLCPFEAIKVKQQTTMPPFCNNV 148 Query: 362 TDGLPKL-VRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQ 529 DG K+ S G YKGIVPLW RQIPYTM KF FE IV+ +Y +PK K++ Sbjct: 149 VDGWKKMYAESGGMKAFYKGIVPLWCRQIPYTMCKFTSFEKIVQKIYS-VLPKKKEE 204
>MPCP_YEAST (P23641) Mitochondrial phosphate carrier protein (Phosphate| transport protein) (PTP) (mPic 1) (Mitochondrial import receptor) (p32) Length = 311 Score = 141 bits (356), Expect = 1e-33 Identities = 70/174 (40%), Positives = 105/174 (60%), Gaps = 1/174 (0%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKY-RDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 ++ P+D+VK +Q++P+ Y + + F ++ +G G G+ TL+GYS QGA KFG Sbjct: 34 SMVPIDVVKTRIQLEPTVYNKGMVGSFKQIIAGEGAGALLTGFGPTLLGYSIQGAFKFGG 93 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE FKK + D G + A R K +Y+ ++A AE +AD+ALCP+EA ++R+ +QP FA L Sbjct: 94 YEVFKKFFIDNLGYDTASRYKNSVYMGSAAMAEFLADIALCPLEATRIRLVSQPQFANGL 153 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPK 523 G ++++ EG Y G P+ +QIPY + KF FE E Y A PK K Sbjct: 154 VGGFSRILKEEGIGSFYSGFTPILFKQIPYNIAKFLVFERASEFYYGFAGPKEK 207 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/143 (22%), Positives = 65/143 (45%), Gaps = 3/143 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 +A+ PL+ + + P + GF +L+E+G+G F+ G+ L KF Sbjct: 131 IALCPLEATRIRLVSQPQFANGLVGGFSRILKEEGIGSFYSGFTPILFKQIPYNIAKFLV 190 Query: 182 YEYFKKCYSDIAGPEN--ADRLKTVIYLAASASAEVIADLALCPMEAVKVRI-QTQPGFA 352 +E + Y AGP+ + T++ L + +A + A + P + + ++ +T+ Sbjct: 191 FERASEFYYGFAGPKEKLSSTSTTLLNLLSGLTAGLAAAIVSQPADTLLSKVNKTKKAPG 250 Query: 353 RCLTDGLPKLVRSEGAFGLYKGI 421 + L +L + G FG + G+ Sbjct: 251 QSTVGLLAQLAKQLGFFGSFAGL 273
>BT1_MAIZE (P29518) Protein brittle-1, chloroplast precursor| Length = 436 Score = 69.7 bits (169), Expect = 5e-12 Identities = 42/180 (23%), Positives = 84/180 (46%), Gaps = 4/180 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 L P++L+K + ++ Y +++ F +L+++G ++G +L+G AC F Sbjct: 245 LCTYPMELIKTRVTIEKDVYDNVAHAFVKILRDEGPSELYRGLTPSLIGVVPYAACNFYA 304 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE K+ Y G + V L ++A IA A P+E + ++Q R + Sbjct: 305 YETLKRLYRRATGRRPGADVGPVATLLIGSAAGAIASSATFPLEVARKQMQVGAVGGRQV 364 Query: 362 TDGLPK----LVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQ 529 + +++ EGA GLY+G+ P + +P + F C+E +++ + +D+ Sbjct: 365 YQNVLHAIYCILKKEGAGGLYRGLGPSCIKLMPAAGIAFMCYEACKKILVDKEDEEEEDE 424 Score = 56.6 bits (135), Expect = 4e-08 Identities = 39/167 (23%), Positives = 74/167 (44%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 V PL+ ++ ++ V ++ F ++Q +G G F+G ++ + A + Y+ Sbjct: 152 VAPLETIRTHLMVGSIGVDSMAGVFQWIMQNEGWTGLFRGNAVNVLRVAPSKAIEHFTYD 211 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTD 367 KK + + ++ L A A A + L PME +K R+ + + Sbjct: 212 TAKKFLTPKG--DEPPKIPIPTPLVAGALAGFASTLCTYPMELIKTRVTIEKDVYDNVAH 269 Query: 368 GLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 K++R EG LY+G+ P +PY F +ET+ + +Y+ A Sbjct: 270 AFVKILRDEGPSELYRGLTPSLIGVVPYAACNFYAYETL-KRLYRRA 315
>MFTC_HUMAN (Q9H2D1) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 68.2 bits (165), Expect = 1e-11 Identities = 43/143 (30%), Positives = 71/143 (49%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 +Y+ + + + +G+ G +KG++ L G +S GA +F YE K Y+ Sbjct: 162 QYKGMFDTLVKIYKYEGVRGLYKGFVPGLFG-TSHGALQFMAYELLKLKYNQHINRLPEA 220 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYK 415 +L TV Y++ +A +++ A A P + V+ R+Q Q F + D + K R EG G YK Sbjct: 221 QLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYK 280 Query: 416 GIVPLWGRQIPYTMMKFACFETI 484 GI P R P + F +E + Sbjct: 281 GIAPNLIRVTPACCITFVVYENV 303 Score = 37.7 bits (86), Expect = 0.020 Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 10/80 (12%) Frame = +2 Query: 257 LAASASAEVIADLALCPMEAVKVR------IQTQP---GFARCLTDGLPKLVRSEGAFGL 409 L A S V+++LAL P++ VK+R ++ +P G CLT + + +G GL Sbjct: 26 LIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLT----TIWKLDGLRGL 81 Query: 410 YKGIVP-LWGRQIPYTMMKF 466 Y+G+ P +WG + + + F Sbjct: 82 YQGVTPNIWGAGLSWGLYFF 101
>MFTC_MACFA (Q95J75) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/143 (30%), Positives = 71/143 (49%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 +Y+ + + + +G+ G +KG++ L G +S GA +F YE K Y+ Sbjct: 162 QYKGMFDTLVKIYKYEGVRGLYKGFVPGLFG-TSHGALQFMAYELLKLKYNQHINRLPEA 220 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYK 415 +L TV Y++ +A +++ A A P + V+ R+Q Q F + D + K R EG G YK Sbjct: 221 QLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGIGGFYK 280 Query: 416 GIVPLWGRQIPYTMMKFACFETI 484 GI P R P + F +E + Sbjct: 281 GIAPNLIRVTPACCITFVVYENV 303 Score = 37.7 bits (86), Expect = 0.020 Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 10/80 (12%) Frame = +2 Query: 257 LAASASAEVIADLALCPMEAVKVR------IQTQP---GFARCLTDGLPKLVRSEGAFGL 409 L A S V+++LAL P++ VK+R ++ +P G CLT + + +G GL Sbjct: 26 LVAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLT----TIWKLDGLRGL 81 Query: 410 YKGIVP-LWGRQIPYTMMKF 466 Y+G+ P +WG + + + F Sbjct: 82 YQGVTPNVWGAGLSWGLYFF 101
>MFTC_MOUSE (Q8BMG8) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 316 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/148 (29%), Positives = 72/148 (48%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 +Y+ + + + +G+ G +KG++ L G +S GA +F YE K Y+ Sbjct: 162 QYKGMFDALVKIYKYEGVRGLYKGFVPGLFG-TSHGALQFMAYELLKLKYNKHINRLPEA 220 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYK 415 +L T Y++ +A +++ A A P + V+ R+Q Q +TD + K R EG G YK Sbjct: 221 QLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTDVITKTWRKEGIGGFYK 280 Query: 416 GIVPLWGRQIPYTMMKFACFETIVEMVY 499 GI P R P + F +E + +Y Sbjct: 281 GIAPNLIRVTPACCITFVVYENVSHFLY 308 Score = 37.0 bits (84), Expect = 0.035 Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 6/76 (7%) Frame = +2 Query: 257 LAASASAEVIADLALCPMEAVKVRIQTQPGFA-----RCLTDGLPKLVRSEGAFGLYKGI 421 L A S V+++LAL P++ VK+R G + + L + + +G GLY+G+ Sbjct: 26 LVAGVSGGVLSNLALHPLDLVKIRFAVSDGLEVRPKYKGILHCLATIWKVDGLRGLYQGV 85 Query: 422 VP-LWGRQIPYTMMKF 466 P +WG + + + F Sbjct: 86 TPNVWGAGLSWGLYFF 101 Score = 29.6 bits (65), Expect = 5.6 Identities = 15/61 (24%), Positives = 27/61 (44%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 A P +V+ +Q Y ++ +++G+GGF+KG L+ + F Y Sbjct: 241 ATYPYQVVRARLQDQHVSYGGVTDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVY 300 Query: 185 E 187 E Sbjct: 301 E 301
>YM39_YEAST (Q03829) Putative mitochondrial carrier YMR166C| Length = 368 Score = 67.4 bits (163), Expect = 2e-11 Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 13/179 (7%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--KYRDISSGFGVLLQEQGLG-GFFKGWMATLVGYSSQGACKF 175 A+ LD VK Q P+ KYR++ S + + E+G+ G + G+MA ++G A F Sbjct: 70 AMHSLDTVKTRQQGAPNVKKYRNMISAYRTIWLEEGVRRGLYGGYMAAMLGSFPSAAIFF 129 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR 355 G YEY K+ E+ T+ +L+A + I+ P E +K R+Q Q F Sbjct: 130 GTYEYTKRTMI-----EDWQINDTITHLSAGFLGDFISSFVYVPSEVLKTRLQLQGRFNN 184 Query: 356 ----------CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 L + + +++ EG L+ G R +P++ ++FA +E ++ +K Sbjct: 185 PFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKFRQLAFK 243 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/146 (25%), Positives = 62/146 (42%), Gaps = 23/146 (15%) Frame = +2 Query: 59 YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD- 235 Y ++ + +++E+G F G+ ATL A +F FYE F++ I + D Sbjct: 193 YSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKFRQLAFKIEQKDGRDG 252 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC----------LTDGLP--- 376 L + A A +A + PM+ VK R+QTQ ++ +T+G P Sbjct: 253 ELSIPNEILTGACAGGLAGIITTPMDVVKTRVQTQQPPSQSNKSYSVTHPHVTNGRPAAL 312 Query: 377 ---------KLVRSEGAFGLYKGIVP 427 + +SEG G + G+ P Sbjct: 313 SNSISLSLRTVYQSEGVLGFFSGVGP 338
>ORNT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute carrier| family 25 member 2) Length = 301 Score = 65.5 bits (158), Expect = 9e-11 Identities = 36/108 (33%), Positives = 55/108 (50%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P D +K MQ P Y+ ++ F + GL GF+KG L+ Y ++ + F Y + Sbjct: 29 PFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGTGPALMAYVAENSVLFMCYGFC 88 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT 337 ++ +AG + +L + AA + A A LALCP E VK R+QT Sbjct: 89 QQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKCRLQT 136 Score = 52.8 bits (125), Expect = 6e-07 Identities = 50/182 (27%), Positives = 78/182 (42%), Gaps = 15/182 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVD---------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYS 154 LA+ P +LVKC +Q + I S +L++ G GF+ G +TL+ Sbjct: 122 LALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLL--- 178 Query: 155 SQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 +G F F+ ++ S A + D L V + + A + L + P++ +K RIQ Sbjct: 179 QEGPGYFFFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLIVFPVDCIKSRIQ 238 Query: 335 T------QPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 Q GF L +VR+EG LY G+ R IP F +E +M+ Sbjct: 239 VLSMYGKQAGFIGTLLS----VVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMM 294 Query: 497 YK 502 K Sbjct: 295 MK 296 Score = 39.3 bits (90), Expect = 0.007 Identities = 26/90 (28%), Positives = 38/90 (42%) Frame = +2 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKG 418 ++ I L A A+ L P + +KV++QT P + LTD K G G YKG Sbjct: 7 IQAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKG 66 Query: 419 IVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 P + + F C+ + V K A Sbjct: 67 TGPALMAYVAENSVLFMCYGFCQQFVRKVA 96
>ORNT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 63.9 bits (154), Expect = 3e-10 Identities = 42/164 (25%), Positives = 69/164 (42%), Gaps = 9/164 (5%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P D +K MQ P YR ++ + G GF+KG L+ ++ + F Y + Sbjct: 29 PFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFC 88 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ---------PG 346 ++ +AG + +L + AA + A A L LCP E VK R+QT Sbjct: 89 QQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAK 148 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 + + ++R +G G Y G+ R++P F +E Sbjct: 149 SQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE 192 Score = 47.8 bits (112), Expect = 2e-05 Identities = 45/174 (25%), Positives = 71/174 (40%), Gaps = 15/174 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVD---------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYS 154 L + P +LVKC +Q + S +L++ G GF+ G +TL+ Sbjct: 122 LVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREV 181 Query: 155 SQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 FG YE + + A + D L V + + + LA+ P++ +K RIQ Sbjct: 182 PGYFFFFGGYELSRSFF---ASGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQ 238 Query: 335 T------QPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 Q GF R + +V++EG LY G+ P R P F +E Sbjct: 239 VLSMSGKQAGFIRTFIN----VVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/90 (31%), Positives = 39/90 (43%) Frame = +2 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKG 418 ++ I L A A+ L P + +KV++QT P R LTD K G G YKG Sbjct: 7 IQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKG 66 Query: 419 IVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 P I + F C+ ++V K A Sbjct: 67 TSPALIANIAENSVLFMCYGFCQQVVRKVA 96
>UCP4_HUMAN (O95847) Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier| family 25 member 27) Length = 323 Score = 63.9 bits (154), Expect = 3e-10 Identities = 47/175 (26%), Positives = 78/175 (44%), Gaps = 15/175 (8%) Frame = +2 Query: 14 PLDLVKCNMQVD--------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 P DLVK MQ++ P ++R + F +L E G+ G + GW+ + + Sbjct: 147 PTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMG 206 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG- 346 Y+ K + D + T + +S + ++A + P + +K RI QP Sbjct: 207 DLTTYDTVKHYL--VLNTPLEDNIMT--HGLSSLCSGLVASILGTPADVIKSRIMNQPRD 262 Query: 347 ------FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEM 493 + TD L + V+ EG LYKG +P W R P++M+ + +E I EM Sbjct: 263 KQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIREM 317
>ORNT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 62.4 bits (150), Expect = 8e-10 Identities = 41/164 (25%), Positives = 68/164 (41%), Gaps = 9/164 (5%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P D +K MQ P YR ++ + G GF+KG L+ ++ + F Y + Sbjct: 29 PFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFC 88 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ---------PG 346 ++ + G + +L + AA + A A L LCP E VK R+QT Sbjct: 89 QQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAA 148 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 + + ++ R +G G Y G+ R++P F +E Sbjct: 149 SQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE 192 Score = 44.7 bits (104), Expect = 2e-04 Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 11/170 (6%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVD---------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYS 154 L + P +LVKC +Q + + S + ++ G GF+ G +TL+ Sbjct: 122 LVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREV 181 Query: 155 SQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 FG YE + + A + D L V + + + LA+ P++ +K RIQ Sbjct: 182 PGYFFFFGGYELSRSFF---ASGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQ 238 Query: 335 --TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 + G L +V++EG LY G+ P R P F +E Sbjct: 239 VLSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288 Score = 39.7 bits (91), Expect = 0.005 Identities = 27/88 (30%), Positives = 38/88 (43%) Frame = +2 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKG 418 ++ I L A A+ L P + +KV++QT P R LTD K G G YKG Sbjct: 7 IQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKG 66 Query: 419 IVPLWGRQIPYTMMKFACFETIVEMVYK 502 P I + F C+ ++V K Sbjct: 67 TSPALIANIAENSVLFMCYGFCQQVVRK 94
>MFRN2_BRARE (Q7T292) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) Length = 376 Score = 62.0 bits (149), Expect = 1e-09 Identities = 46/165 (27%), Positives = 74/165 (44%), Gaps = 4/165 (2%) Frame = +2 Query: 14 PLDLVKCNMQ-VDP---SKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P+D VK MQ + P ++YR++ +++ +G+ +G T VG A F Sbjct: 97 PIDCVKTRMQSLQPEPAARYRNVMDALWRIMRTEGIWRPIRGLNITAVGAGPAHALYFAC 156 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE KK SDI P L AA A ++ D A+ P E VK R+Q R + Sbjct: 157 YERLKKVLSDIIHPGANSHLANG---AAGCVATLLHDAAMNPTEVVKQRMQMYNSPYRSV 213 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 D + + + EGA Y+ +P+ + F +E + E++ Sbjct: 214 LDCMRCVWQREGALAFYRSYTTQLTMNVPFQALHFMTYEYLQELL 258 Score = 45.1 bits (105), Expect = 1e-04 Identities = 43/186 (23%), Positives = 73/186 (39%), Gaps = 11/186 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 A+ P ++VK MQ+ S YR + + Q +G F++ + L A F Y Sbjct: 192 AMNPTEVVKQRMQMYNSPYRSVLDCMRCVWQREGALAFYRSYTTQLTMNVPFQALHFMTY 251 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA---- 352 EY + ++ P+ ++ + A A IA A P++ K + TQ A Sbjct: 252 EYLQ----ELLNPQR--HYNPSSHMVSGALAGAIAAAATTPLDVCKTLLNTQESLAVDSV 305 Query: 353 -------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAV 511 L + R G +KG+ Q+P T + ++ +E M+ KH Sbjct: 306 SRSGRHITGLGHAFRTVYRLGGLPAYFKGVQARVIYQMPSTAISWSVYEFFKYMITKHQH 365 Query: 512 PKPKDQ 529 K + Q Sbjct: 366 EKRRIQ 371
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein| Length = 292 Score = 61.6 bits (148), Expect = 1e-09 Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 9/170 (5%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVD-------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 L + P++LVKC +QV +K+ + ++ E+GL G ++G T + S Sbjct: 123 LVLTPVELVKCKLQVANLQVASAKTKHTKVLPTIKAIITERGLAGLWQGQSGTFIRESFG 182 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIY--LAASASAEVIADLALCPMEAVKVRIQ 334 G F YE KK D ++ R ++ I+ L + SA + + ++ P + VK +Q Sbjct: 183 GVAWFATYEIVKKSLKDRHSLDDPKRDESKIWELLISGGSAGLAFNASIFPADTVKSVMQ 242 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 T+ LT+ + K+ G G Y+G+ R +P F FET+ Sbjct: 243 TEH---ISLTNAVKKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFETL 289 Score = 37.7 bits (86), Expect = 0.020 Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 10/185 (5%) Frame = +2 Query: 14 PLDLVKCNMQVDPSK-YRDISSGFGVLLQEQGLG-GFFKGWMATLVGYSSQGACKFGFYE 187 P D VK +Q S + S Q +G+ GFF+G + LVG + A F Y Sbjct: 33 PFDTVKVRLQTQASNVFPTTWSCIKFTYQNEGIARGFFQGIASPLVGACLENATLFVSY- 91 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT---QPGFARC 358 +C + N L + L + A A L L P+E VK ++Q Q A+ Sbjct: 92 --NQCSKFLEKHTNVFPLGQI--LISGGVAGSCASLVLTPVELVKCKLQVANLQVASAKT 147 Query: 359 L-TDGLP---KLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY-KHAVPKPK 523 T LP ++ G GL++G + R+ + FA +E + + + +H++ PK Sbjct: 148 KHTKVLPTIKAIITERGLAGLWQGQSGTFIRESFGGVAWFATYEIVKKSLKDRHSLDDPK 207 Query: 524 DQCSK 538 SK Sbjct: 208 RDESK 212
>TXTP_CAEEL (P34519) Putative tricarboxylate transport protein, mitochondrial| precursor (Citrate transport protein) (CTP) Length = 312 Score = 61.2 bits (147), Expect = 2e-09 Identities = 47/169 (27%), Positives = 74/169 (43%), Gaps = 5/169 (2%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 AV P++ VK D KY+ G G +++ +GLGG +KG AT+ S A + Sbjct: 139 AVTPMETVKVKFIHDQGLAQPKYKGFVHGVGCIVKAEGLGGIYKGVTATMAKQGSNQAIR 198 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ-TQPGF 349 F E K Y G +N + I A A + P++ VK R+Q + Sbjct: 199 FFVMETLKDWY---RGGDNTQPISKPIVGLMGAVAGAASVYGNTPIDVVKTRMQGLEAKK 255 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 + D ++ + EG F YKG VP R + F +++I+E + Sbjct: 256 YKNTLDCAMQIWKKEGFFAFYKGTVPRLSRVCLDVGITFMIYDSIIEFL 304 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/166 (27%), Positives = 72/166 (43%), Gaps = 9/166 (5%) Frame = +2 Query: 14 PLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P + VK +Q+D K+R + G G ++G L G + + +FG Sbjct: 45 PTEYVKTQLQLDERSATPKFRGPIDCVKQTVNGHGFFGLYRGLSVLLYGSIPKSSFRFGT 104 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVI-ADLALCPMEAVKVRIQTQPGFA-- 352 +EY K +D G L V+ L A + A A+ PME VKV+ G A Sbjct: 105 FEYLKSQAADERG-----NLSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQGLAQP 159 Query: 353 --RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 + G+ +V++EG G+YKG+ +Q ++F ET+ Sbjct: 160 KYKGFVHGVGCIVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETL 205
>ODC_MOUSE (Q8BZ09) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 60.5 bits (145), Expect = 3e-09 Identities = 50/188 (26%), Positives = 85/188 (45%), Gaps = 17/188 (9%) Frame = +2 Query: 14 PLDLVKCNMQV-----DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 PLD+VK QV DP YR + F ++ + +GL GF+KG + ++ + + A KF Sbjct: 32 PLDVVKTRFQVQRSVTDPQSYRTVRGSFQMIFRTEGLFGFYKGIIPPILAETPKRAVKFS 91 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT------- 337 +E +KK ++ + +L A + + + + P E VKV +Q Sbjct: 92 TFELYKKFLGYMSLSPG------LTFLIAGLGSGLTEAVVVNPFEVVKVGLQVNRNLFKE 145 Query: 338 QP---GFARCLTDGLPKLVRSEGA--FGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 QP +AR ++++ EG GL KG+ GR + M+ F + + K Sbjct: 146 QPSTFAYAR-------QIIKKEGLGFQGLNKGLTATLGRHGIFNMVYFGFYHNV-----K 193 Query: 503 HAVPKPKD 526 + +P KD Sbjct: 194 NIIPSSKD 201 Score = 45.8 bits (107), Expect = 7e-05 Identities = 43/153 (28%), Positives = 64/153 (41%), Gaps = 11/153 (7%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGV---LLQEQGLG--GFFKGWMATLVGYSSQGA 166 + V P ++VK +QV+ + +++ S F +++++GLG G KG ATL + Sbjct: 124 VVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGLTATLGRHGIFNM 183 Query: 167 CKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-- 340 FGFY K P K I + V P + K RIQ Sbjct: 184 VYFGFYHNVKNIIPSSKDPTLEFLRKFGIGFVSGTMGSVFN----IPFDVAKSRIQGPQP 239 Query: 341 -PG---FARCLTDGLPKLVRSEGAFGLYKGIVP 427 PG + C + + R EG LYKG+VP Sbjct: 240 VPGEIKYRSCFKT-MEMIYREEGILALYKGLVP 271
>ODC_HUMAN (Q9BQT8) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 60.1 bits (144), Expect = 4e-09 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 17/178 (9%) Frame = +2 Query: 14 PLDLVKCNMQV-----DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 PLD+VK Q+ DP+ Y+ + F ++ Q +GL GF+KG + ++ + + A KF Sbjct: 33 PLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFF 92 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT------- 337 +E +KK ++ + + A + + + + P E VKV +Q Sbjct: 93 TFEQYKKLLGYVS------LSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAE 146 Query: 338 QP---GFARCLTDGLPKLVRSE--GAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 QP G+AR ++++ E G GL KG+ GR + M+ F + + M+ Sbjct: 147 QPSTVGYAR-------QIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI 197
>DNC_MACFA (Q5IS35) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 60.1 bits (144), Expect = 4e-09 Identities = 46/180 (25%), Positives = 81/180 (45%), Gaps = 11/180 (6%) Frame = +2 Query: 8 VXPLDLVKCNMQV--------DPS-KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 + P D++K Q+ DP+ KY I +LQE+GL F+KG + + Sbjct: 33 ISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQILQEEGLTAFWKGHIPAQILSIGY 92 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRI--Q 334 GA +F +E + + D + ++ A A L + P++ ++ R Q Sbjct: 93 GAVQFLSFEMLTEL---VHRGSVYDAREFSVHFVCGGLAACTATLTVHPVDVLRTRFAAQ 149 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVP 514 +P L + + RSEG YKG+ P PY ++F+C+ ++ + +YK A+P Sbjct: 150 GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL-KHLYKWAMP 208 Score = 50.4 bits (119), Expect = 3e-06 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 14/156 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNM--QVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 L V P+D+++ Q +P Y + G + + +G F+KG TL+ +F Sbjct: 134 LTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR 355 Y K Y A P + + + L + A VI+ P++ K R+Q GF Sbjct: 194 SCYSSLKHLYK-WAMPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVG-GFEH 251 Query: 356 C------------LTDGLPKLVRSEGAFGLYKGIVP 427 L D ++++ EGA G +KG+ P Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287 Score = 31.6 bits (70), Expect = 1.5 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 11/71 (15%) Frame = +2 Query: 14 PLDLVKCNMQV-----------DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 PLDL K +QV +Y+ + +LQ++G GFFKG +L+ + Sbjct: 236 PLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALS 295 Query: 161 GACKFGFYEYF 193 F +YE+F Sbjct: 296 TGFMFFWYEFF 306
>DNC_HUMAN (Q9HC21) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) (Mitochondrial uncoupling protein 1) Length = 320 Score = 60.1 bits (144), Expect = 4e-09 Identities = 46/180 (25%), Positives = 81/180 (45%), Gaps = 11/180 (6%) Frame = +2 Query: 8 VXPLDLVKCNMQV--------DPS-KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 + P D++K Q+ DPS KY I +LQE+G F+KG + + Sbjct: 33 ISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGY 92 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRI--Q 334 GA +F +E + + D + ++ A +A L + P++ ++ R Q Sbjct: 93 GAVQFLSFEMLTEL---VHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ 149 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVP 514 +P L + + RSEG YKG+ P PY ++F+C+ ++ + +YK A+P Sbjct: 150 GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL-KHLYKWAIP 208 Score = 50.1 bits (118), Expect = 4e-06 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 14/156 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNM--QVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 L V P+D+++ Q +P Y + G + + +G F+KG TL+ +F Sbjct: 134 LTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR 355 Y K Y A P + + + L + A VI+ P++ K R+Q GF Sbjct: 194 SCYSSLKHLYK-WAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVG-GFEH 251 Query: 356 C------------LTDGLPKLVRSEGAFGLYKGIVP 427 L D ++++ EGA G +KG+ P Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287 Score = 30.4 bits (67), Expect = 3.3 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 11/71 (15%) Frame = +2 Query: 14 PLDLVKCNMQV-----------DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 PLDL K +QV +Y+ + +LQ++G GFFKG +L+ + Sbjct: 236 PLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALS 295 Query: 161 GACKFGFYEYF 193 F YE+F Sbjct: 296 TGFMFFSYEFF 306
>MFRN2_MOUSE (Q8R0Z5) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) Length = 364 Score = 60.1 bits (144), Expect = 4e-09 Identities = 45/163 (27%), Positives = 72/163 (44%), Gaps = 4/163 (2%) Frame = +2 Query: 14 PLDLVKCNMQV---DPS-KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P+D VK MQ DP+ +YR++ +++ +GL +G T G A F Sbjct: 92 PIDCVKTRMQSLQPDPAARYRNVLEALWRIMRTEGLWRPMRGLNVTATGAGPAHALYFAC 151 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE KK SD+ P + AA A ++ D A+ P E VK R+Q + Sbjct: 152 YEKLKKTLSDVIHPGGNSHIANG---AAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRV 208 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 TD + + ++EGA Y+ +P+ + F +E + E Sbjct: 209 TDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQE 251 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/175 (20%), Positives = 71/175 (40%), Gaps = 9/175 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 A+ P ++VK MQ+ S Y ++ + Q +G G F++ + L A F Y Sbjct: 187 AMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTY 246 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-------- 340 E+ ++ ++ P+ R ++ A A +A A P++ K + TQ Sbjct: 247 EFLQEHFN----PQR--RYNPSSHVLCGACAGAVAAAATTPLDVCKTLLNTQESLALNSN 300 Query: 341 -PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 G + + + G ++G+ QIP T + ++ +E ++ K Sbjct: 301 ITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITK 355
>MFRN2_HUMAN (Q96A46) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) Length = 364 Score = 60.1 bits (144), Expect = 4e-09 Identities = 45/163 (27%), Positives = 72/163 (44%), Gaps = 4/163 (2%) Frame = +2 Query: 14 PLDLVKCNMQV---DPS-KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P+D VK MQ DP+ +YR++ +++ +GL +G T G A F Sbjct: 92 PIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFAC 151 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE KK SD+ P + AA A ++ D A+ P E VK R+Q + Sbjct: 152 YEKLKKTLSDVIHPGGNSHIANG---AAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRV 208 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 TD + + ++EGA Y+ +P+ + F +E + E Sbjct: 209 TDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQE 251 Score = 42.0 bits (97), Expect = 0.001 Identities = 36/175 (20%), Positives = 72/175 (41%), Gaps = 9/175 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 A+ P ++VK MQ+ S Y ++ + Q +G G F++ + L A F Y Sbjct: 187 AMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTY 246 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-------- 340 E+ ++ ++ P+ R ++ + A A +A A P++ K + TQ Sbjct: 247 EFLQEHFN----PQR--RYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSH 300 Query: 341 -PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 G + + + G ++G+ QIP T + ++ +E ++ K Sbjct: 301 ITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITK 355
>DNC_PONPY (Q5NVC1) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 58.9 bits (141), Expect = 9e-09 Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 11/180 (6%) Frame = +2 Query: 8 VXPLDLVKCNMQV--------DPS-KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 + P D++K Q+ DP+ KY I +LQE+G F+KG + + Sbjct: 33 ISPFDVIKIRFQLQHERLSRSDPNAKYHGILQASRQILQEEGPTAFWKGHIPAQILSIGY 92 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRI--Q 334 GA +F +E + + D + ++ A +A L + P++ ++ R Q Sbjct: 93 GAVQFLSFEMLTEL---VHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ 149 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVP 514 +P L + + RSEG YKG+ P PY ++F+C+ ++ + +YK A+P Sbjct: 150 GEPKVYNTLCHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSL-KHLYKWAIP 208 Score = 50.1 bits (118), Expect = 4e-06 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 14/156 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNM--QVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 L V P+D+++ Q +P Y + G + + +G F+KG TL+ +F Sbjct: 134 LTVHPVDVLRTRFAAQGEPKVYNTLCHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQF 193 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR 355 Y K Y A P + + + L + A VI+ P++ K R+Q GF Sbjct: 194 SCYSSLKHLYK-WAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVG-GFEH 251 Query: 356 C------------LTDGLPKLVRSEGAFGLYKGIVP 427 L D ++++ EGA G +KG+ P Sbjct: 252 ARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSP 287 Score = 31.6 bits (70), Expect = 1.5 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 11/71 (15%) Frame = +2 Query: 14 PLDLVKCNMQV-----------DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 PLDL K +QV +Y+ + +LQ++G GFFKG +L+ + Sbjct: 236 PLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALS 295 Query: 161 GACKFGFYEYF 193 F +YE+F Sbjct: 296 TGFMFFWYEFF 306
>ADT1_ANOGA (Q27238) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 301 Score = 58.2 bits (139), Expect = 1e-08 Identities = 51/191 (26%), Positives = 83/191 (43%), Gaps = 17/191 (8%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I F + +EQG+G F++G +A ++ Y Sbjct: 27 AVAPIERVKLLLQVQAASKQIAVDKQYKGIVDCFVRIPKEQGIGAFWRGNLANVIRYFPT 86 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALC---PMEAVKVRI 331 A F F + +K+ + G + + +L S +LC P++ + R+ Sbjct: 87 QALNFAFKDVYKQVF---LGGVDKNTQFWRYFLGNLGSGGAAGATSLCFVYPLDFARTRL 143 Query: 332 QTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEM 493 G L D L K V+S+G GLY+G I Y F CF+T Sbjct: 144 GADVGRGAGEREFNGLLDCLKKTVKSDGIIGLYRGFNVSVQGIIIYRAAYFGCFDTA--- 200 Query: 494 VYKHAVPKPKD 526 K +P PK+ Sbjct: 201 --KGMLPDPKN 209
>AGC1_ASHGO (Q75AH6) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 911 Score = 58.2 bits (139), Expect = 1e-08 Identities = 49/185 (26%), Positives = 90/185 (48%), Gaps = 6/185 (3%) Frame = +2 Query: 2 LAVXPLDLVKCNMQV--DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 + V P+D+VK MQ D SKY++ +L ++G+ G + G L+G + + A K Sbjct: 539 MVVYPIDMVKTRMQAQRDFSKYKNSIDCLLKILSKEGVRGLYSGLGPQLIGVAPEKAIKL 598 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGF-- 349 ++ + + +AG + L I A+A A + + P+E VK+R+Q + + Sbjct: 599 TVNDHMR---ATLAGRDGKLSLPCEIISGATAGACQV--VFTNPLEIVKIRLQVKSDYVA 653 Query: 350 --ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPK 523 AR + + ++++ G GLY+G R IP++ + F + I V+ PK Sbjct: 654 DAARNSVNAI-SVIKNLGLIGLYRGAGACLLRDIPFSAIYFPTYAHIKSNVFNFD-PKDS 711 Query: 524 DQCSK 538 D+ +K Sbjct: 712 DKRNK 716 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFG----VLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P D++K +Q+DP K + +G +L+E+G+ FFKG A ++ S Q Sbjct: 739 PFDVIKTRLQIDPKKGESVYNGIWDAARTILKEEGIKSFFKGGPARVLRSSPQFGFTLAA 798 Query: 182 YEYFKKCY 205 YE F + Sbjct: 799 YEIFHNLF 806
>TXTP_HUMAN (P53007) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 57.8 bits (138), Expect = 2e-08 Identities = 40/144 (27%), Positives = 69/144 (47%), Gaps = 8/144 (5%) Frame = +2 Query: 14 PLDLVKCNMQVD----PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P + VK +Q+D P +YR I ++ G+ G ++G + L G + A +FG Sbjct: 45 PTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGM 104 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRI---QTQPG-F 349 +E+ D G D + ++ + AE + + +CPME +KV+ QT P Sbjct: 105 FEFLSNHMRDAQG--RLDSTRGLLCGLGAGVAEAV--VVVCPMETIKVKFIHDQTSPNPK 160 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGI 421 R G+ ++VR +G G Y+G+ Sbjct: 161 YRGFFHGVREIVREQGLKGTYQGL 184 Score = 54.7 bits (130), Expect = 2e-07 Identities = 44/172 (25%), Positives = 81/172 (47%), Gaps = 5/172 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNM---QVDPS-KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 + V P++ +K Q P+ KYR G +++EQGL G ++G AT++ S A Sbjct: 138 VVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAI 197 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ-TQPG 346 +F + Y + + L T ++ A + +A V + P++ +K R+Q + Sbjct: 198 RFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGN---TPLDVIKTRMQGLEAH 254 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 R D ++++ EG YKG VP GR + F ++ +V+++ K Sbjct: 255 KYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNK 306 Score = 36.6 bits (83), Expect = 0.045 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%) Frame = +2 Query: 305 PMEAVKVRIQ----TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFAC 472 P E VK ++Q + P R + D + + VRS G GLY+G+ L IP ++F Sbjct: 45 PTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGM 104 Query: 473 FE 478 FE Sbjct: 105 FE 106 Score = 30.4 bits (67), Expect = 3.3 Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Frame = +2 Query: 14 PLDLVKCNMQ-VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 PLD++K MQ ++ KYR+ +L+++GL F+KG + L A F Y+ Sbjct: 240 PLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDE 299 Query: 191 FKKCYSDI 214 K + + Sbjct: 300 VVKLLNKV 307
>ODC_PONPY (Q5RFB7) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 57.4 bits (137), Expect = 2e-08 Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 17/178 (9%) Frame = +2 Query: 14 PLDLVKCNMQV-----DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 PLD+VK Q+ DP+ Y+ + F ++ Q + L GF+KG + ++ + + A KF Sbjct: 33 PLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQTERLFGFYKGILPPILAETPKRAVKFF 92 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT------- 337 +E +KK ++ + + A + + + + P E VKV +Q Sbjct: 93 TFEQYKKLLGYVS------LSPALTFTIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAK 146 Query: 338 QP---GFARCLTDGLPKLVRSE--GAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 QP G+AR ++++ E G GL KG+ GR + M+ F + + M+ Sbjct: 147 QPSTVGYAR-------QIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI 197
>TXTP_RAT (P32089) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 56.2 bits (134), Expect = 6e-08 Identities = 44/172 (25%), Positives = 81/172 (47%), Gaps = 5/172 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 + V P++ VK D + KYR G +++EQGL G ++G AT++ S A Sbjct: 138 VVVCPMETVKVKFIHDQTSSNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAI 197 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ-TQPG 346 +F + Y + + L T ++ A + +A V + P++ +K R+Q + Sbjct: 198 RFFVMTSLRNWYQGDNPNKPMNPLITGVFGAVAGAASVFGN---TPLDVIKTRMQGLEAH 254 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 R D +++++EG YKG VP GR + F ++ +V+++ K Sbjct: 255 KYRNTLDCGVQILKNEGPKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNK 306 Score = 55.8 bits (133), Expect = 7e-08 Identities = 39/145 (26%), Positives = 69/145 (47%), Gaps = 9/145 (6%) Frame = +2 Query: 14 PLDLVKCNMQVD----PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P + VK +Q+D P +YR I ++ G+ G ++G + L G + A +FG Sbjct: 45 PTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGM 104 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRI-----QTQPG 346 +E+ D G D + ++ + AE + + +CPME VKV+ + P Sbjct: 105 FEFLSNHMRDAQG--RLDSRRGLLCGLGAGVAEAV--VVVCPMETVKVKFIHDQTSSNPK 160 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGI 421 + R G+ ++VR +G G Y+G+ Sbjct: 161 Y-RGFFHGVREIVREQGLKGTYQGL 184 Score = 36.2 bits (82), Expect = 0.059 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 4/62 (6%) Frame = +2 Query: 305 PMEAVKVRIQ----TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFAC 472 P E VK ++Q P R + D + + VRS G GLY+G+ L IP ++F Sbjct: 45 PTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGM 104 Query: 473 FE 478 FE Sbjct: 105 FE 106
>CMC2_MOUSE (Q9QXX4) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 676 Score = 55.8 bits (133), Expect = 7e-08 Identities = 43/165 (26%), Positives = 74/165 (44%), Gaps = 8/165 (4%) Frame = +2 Query: 5 AVXPLDLVKCNMQ--------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P+DLVK MQ V Y++ F +L+ +G G ++G + L+G + + Sbjct: 346 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 405 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 A K ++ + + G + L + + ++VI P+E VK+R+Q Sbjct: 406 KAIKLTVNDFVRDKFMHKDG--SVPLLAEIFAGGCAGGSQVIFTN---PLEIVKIRLQVA 460 Query: 341 PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 +VR G FG+YKG + R IP++ + F C+ Sbjct: 461 GEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY 505 Score = 41.6 bits (96), Expect = 0.001 Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 8/170 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGV----LLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 PL++VK +QV +I++G V ++++ G G +KG A + A F Sbjct: 449 PLEIVKIRLQVAG----EITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPC 504 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC- 358 Y + K +++ G + L L A A A + A + P + +K R+Q + Sbjct: 505 YAHVKASFANEDGQVSPGSL-----LLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTT 559 Query: 359 ---LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 +TD K++R EG L+KG+ R P + +E + Y Sbjct: 560 YNGVTDCFRKILREEGPKALWKGVAARVFRSSPQFGVTLLTYELLQRWFY 609
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (mCAC) (Solute carrier family 25 member 20) Length = 301 Score = 55.5 bits (132), Expect = 9e-08 Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 6/169 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 + P + +KC +Q+ S KY L QE G+ GF+KG + TL+ F Sbjct: 128 MTPGERIKCLLQIQASSGENKYSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYF 187 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQP--GF 349 YE+ K ++ ++ L L A A + P + +K R QT P + Sbjct: 188 MTYEWLKNLFTPEG--KSVSDLSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKY 245 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 D L +L+R EG LYKG + R P F FE ++ + Sbjct: 246 PNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFL 294 Score = 29.6 bits (65), Expect = 5.6 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 8/65 (12%) Frame = +2 Query: 305 PMEAVKVRIQT-------QPGFARCLTDGLPKLVRSEGAFGLYKGI-VPLWGRQIPYTMM 460 P++ VKVR+QT QP D K + EG GLY+G+ P+ G T M Sbjct: 30 PLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIG----VTPM 85 Query: 461 KFACF 475 CF Sbjct: 86 FAVCF 90
>MFRN1_BRARE (Q287T7) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Protein frascati) Length = 332 Score = 55.5 bits (132), Expect = 9e-08 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 4/174 (2%) Frame = +2 Query: 14 PLDLVKCNMQV---DP-SKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P+D VK MQ DP ++YR + +++ +GL +G T++G A F Sbjct: 53 PVDSVKTRMQSLQPDPKAQYRSVYGALKRIVRTEGLLRPLRGLNITVLGAGPAHALYFAC 112 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE K+ SD+ + + A + A V+ D + P E VK R+Q R L Sbjct: 113 YERIKRSLSDVIQNGGNSHIANGV---AGSVATVLHDAVMNPAEVVKQRMQMYNSPYRSL 169 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPK 523 D + + R EG Y+ IP+ + F +E + E H +P+ Sbjct: 170 YDCVLMVSRKEGLAAFYRSYSTQLTMNIPFQAVHFITYEFMQEHFNPHRQYRPE 223 Score = 42.0 bits (97), Expect = 0.001 Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 10/174 (5%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P ++VK MQ+ S YR + ++ +++GL F++ + L A F YE+ Sbjct: 151 PAEVVKQRMQMYNSPYRSLYDCVLMVSRKEGLAAFYRSYSTQLTMNIPFQAVHFITYEFM 210 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ----------P 343 ++ ++ P R +T ++ + A+A ++ P++ K + TQ Sbjct: 211 QEHFN----PHRQYRPET--HIISGAAAGAVSAAVTTPLDVCKTLLNTQENVALSSAHVS 264 Query: 344 GFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKH 505 G + + L + R G +KGI Q+P T + ++ +E + +H Sbjct: 265 GHLSGMVNALRTVYRLGGVPAFFKGIQARVIYQMPSTAIAWSVYEFFKYFLTQH 318
>YEA6_YEAST (P39953) Putative mitochondrial carrier YEL006W| Length = 335 Score = 55.5 bits (132), Expect = 9e-08 Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 14/156 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVD--------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSS 157 + V P D+ K +Q Y+ F + +++G G +KG T++GY Sbjct: 54 MLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFATIFKDEGAAGLYKGLQPTVLGYIP 113 Query: 158 QGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT 337 F Y++ +K DI + +++ +A I+ +A P+ VK R+ Sbjct: 114 TLMIYFSVYDFCRKYSVDI-----FPHSPFLSNASSAITAGAISTVATNPIWVVKTRLML 168 Query: 338 QPGFARCLT------DGLPKLVRSEGAFGLYKGIVP 427 Q G + T D K+++ EGA LY G+VP Sbjct: 169 QTGIGKYSTHYKGTIDTFRKIIQQEGAKALYAGLVP 204 Score = 33.9 bits (76), Expect = 0.29 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 9/94 (9%) Frame = +2 Query: 224 ENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDG---------LP 376 +NAD I A S + ++ + +CP + K R+Q Q G Sbjct: 34 KNADPRVAAISGALSGA---LSAMLVCPFDVAKTRLQAQ-GLQNMTHQSQHYKGFFGTFA 89 Query: 377 KLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 + + EGA GLYKG+ P IP M+ F+ ++ Sbjct: 90 TIFKDEGAAGLYKGLQPTVLGYIPTLMIYFSVYD 123
>TXTP_BOVIN (P79110) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 55.5 bits (132), Expect = 9e-08 Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 6/173 (3%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 + V P++ +K D + KYR G +++EQGL G ++G AT++ S Sbjct: 138 VVVCPMETIKVKFIHDQTSASPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQGI 197 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG- 346 +F + Y + + L T ++ A + +A V + P++ +K R+Q Sbjct: 198 RFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGN---TPLDVIKTRMQGLEAH 254 Query: 347 -FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 + L GL +++R+EG YKG VP GR + F ++ +V+++ K Sbjct: 255 KYRNTLDCGL-QILRNEGLKAFYKGTVPRLGRVCLDVAIVFIIYDEVVKLLNK 306 Score = 54.7 bits (130), Expect = 2e-07 Identities = 42/146 (28%), Positives = 67/146 (45%), Gaps = 10/146 (6%) Frame = +2 Query: 14 PLDLVKCNMQVD----PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P + VK +Q+D P +YR I ++ GL G ++G + L G + A +FG Sbjct: 45 PTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGLLGLYRGLSSLLYGSIPKAAVRFGT 104 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEV-IADLALCPMEAVKVRI-----QTQP 343 +E+ D G RL + L A V A + +CPME +KV+ P Sbjct: 105 FEFLSNHMRDAQG-----RLDSTRGLLCGLGAGVPEAVVVVCPMETIKVKFIHDQTSASP 159 Query: 344 GFARCLTDGLPKLVRSEGAFGLYKGI 421 + R G+ ++VR +G G Y+G+ Sbjct: 160 KY-RGFFHGVREIVREQGLKGTYQGL 184 Score = 36.2 bits (82), Expect = 0.059 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 4/62 (6%) Frame = +2 Query: 305 PMEAVKVRIQ----TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFAC 472 P E VK ++Q + P R + D + + VRS G GLY+G+ L IP ++F Sbjct: 45 PTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGLLGLYRGLSSLLYGSIPKAAVRFGT 104 Query: 473 FE 478 FE Sbjct: 105 FE 106 Score = 30.0 bits (66), Expect = 4.3 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Frame = +2 Query: 14 PLDLVKCNMQ-VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 PLD++K MQ ++ KYR+ +L+ +GL F+KG + L A F Y+ Sbjct: 240 PLDVIKTRMQGLEAHKYRNTLDCGLQILRNEGLKAFYKGTVPRLGRVCLDVAIVFIIYDE 299 Query: 191 FKKCYSDI 214 K + + Sbjct: 300 VVKLLNKV 307
>CMC1_YEAST (P48233) Calcium-binding mitochondrial carrier SAL1 (Suppressor of| AAC2 lethality) Length = 545 Score = 55.5 bits (132), Expect = 9e-08 Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 15/175 (8%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDP--SKYRDISSGFGV---LLQEQGLGGFFKGWMATLVGYSSQGAC 169 +V P+D +K +Q P +K + + F + +E GL F++G +VG A Sbjct: 364 SVYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGLRLFYRGVTVGIVGIFPYAAL 423 Query: 170 KFGFYEYFKKCY-----SDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 G + KK Y + P++ L ++ L A + + + P+ ++ R+Q Sbjct: 424 DLGTFSALKKWYIAKQAKTLNLPQDQVTLSNLVVLPMGAFSGTVGASVVYPINLLRTRLQ 483 Query: 335 TQPGFARCLT-----DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 Q +A D L K + EG GL+KG+VP + P + + C+E + Sbjct: 484 AQGTYAHPYVYNGFKDVLLKTLEREGYQGLFKGLVPTLAKVCPAVSISYLCYENL 538
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2| Length = 307 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/148 (24%), Positives = 70/148 (47%), Gaps = 12/148 (8%) Frame = +2 Query: 14 PLDLVKCNMQVDPS------------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSS 157 PLD+VK Q++ + +Y + +++++G ++G + ++ + Sbjct: 32 PLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEGFSRLYRGISSPMLMEAP 91 Query: 158 QGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT 337 + A KF + ++K + ++ N + I +AA ASA + + P E +K+R+Q Sbjct: 92 KRATKFACNDQYQKIFKNLF---NTNETTQKISIAAGASAGMTEAAVIVPFELIKIRMQD 148 Query: 338 QPGFARCLTDGLPKLVRSEGAFGLYKGI 421 D L K +++EG GLYKGI Sbjct: 149 VKSSYLGPMDCLKKTIKNEGIMGLYKGI 176 Score = 38.1 bits (87), Expect = 0.016 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 6/153 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 + P +L+K MQ S Y ++ +G+ G +KG +T+ + FG Sbjct: 136 IVPFELIKIRMQDVKSSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNALWNGGYFGVI- 194 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTD 367 Y + +A + KT L A A + + P + VK RIQ+ + + Sbjct: 195 YQVRNSMPVAKTKGQ---KTRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVDAVSSAVKK 251 Query: 368 ---GLPKLV---RSEGAFGLYKGIVPLWGRQIP 448 LP L+ R EG LYKG VP R P Sbjct: 252 YNWCLPSLLVIYREEGFRALYKGFVPKVCRLAP 284 Score = 33.9 bits (76), Expect = 0.29 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 12/99 (12%) Frame = +2 Query: 212 IAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ---TQPGFARC-------- 358 ++ NA L + + A A + + P++ VK R Q T P A Sbjct: 1 MSSDSNAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYN 60 Query: 359 -LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFAC 472 + D L K+V+ EG LY+GI + P KFAC Sbjct: 61 GVIDCLKKIVKKEGFSRLYRGISSPMLMEAPKRATKFAC 99
>CMC3_CAEEL (Q19529) Probable calcium-binding mitochondrial carrier F17E5.2| Length = 531 Score = 55.1 bits (131), Expect = 1e-07 Identities = 44/168 (26%), Positives = 76/168 (45%), Gaps = 4/168 (2%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDIS--SGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 P D +K +QV+ +K + S +L E G+ F++G ++ + + A KF Y+ Sbjct: 264 PFDRIKVYLQVNSTKTNKLGVVSCVHLLHAEGGIKSFWRGNGINVIKIAPESAMKFMCYD 323 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG--FARCL 361 K+ + G L T+ L A +SA I+ A+ PME +K R+ + + + Sbjct: 324 QIKRWMQEYKG---GAELSTIERLLAGSSAGAISQTAIYPMEVMKTRLALRRTGQLDKGM 380 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKH 505 K+ EG YKG +P IPY + +E++ M K+ Sbjct: 381 FHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGIDLTVYESLKSMYTKY 428 Score = 45.8 bits (107), Expect = 7e-05 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 15/175 (8%) Frame = +2 Query: 5 AVXPLDLVKCNM------QVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGA 166 A+ P++++K + Q+D + + ++G+ F+KG++ L+G Sbjct: 357 AIYPMEVMKTRLALRRTGQLDKGMFHFAHK----MYTKEGIKCFYKGYLPNLLGIIPYAG 412 Query: 167 CKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ---- 334 YE K Y+ + + LA + LA P+ V+ R+Q Sbjct: 413 IDLTVYESLKSMYTKYYTEHTEPGVLAL--LACGTCSSTCGQLASYPLALVRTRLQARAI 470 Query: 335 -----TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 TQP + ++++EG GLY+GI P + + IP + + +E + Sbjct: 471 SPKNSTQPD---TMVGQFKHILQTEGFTGLYRGITPNFMKVIPAVSISYVVYEKV 522
>CMC2_MACFA (Q8HXW2) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 674 Score = 55.1 bits (131), Expect = 1e-07 Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQ--------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P+DLVK MQ V Y++ F +L+ +G G ++G + L+G + + Sbjct: 345 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 404 Query: 161 GACKFGFYEYF--KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 A K ++ K + D + P A+ ++ + ++VI P+E VK+R+Q Sbjct: 405 KAIKLTVNDFVRDKFMHKDGSVPLAAE----ILAGGCAGGSQVIFTN---PLEIVKIRLQ 457 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 +VR G FG+YKG + R IP++ + F C+ Sbjct: 458 VAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY 504
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 675 Score = 55.1 bits (131), Expect = 1e-07 Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQ--------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P+DLVK MQ V Y++ F +L+ +G G ++G + L+G + + Sbjct: 345 AVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPE 404 Query: 161 GACKFGFYEYF--KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 A K ++ K + D + P A+ ++ + ++VI P+E VK+R+Q Sbjct: 405 KAIKLTVNDFVRDKFMHKDGSVPLAAE----ILAGGCAGGSQVIFTN---PLEIVKIRLQ 457 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 +VR G FG+YKG + R IP++ + F C+ Sbjct: 458 VAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY 504
>CMC2_CAEEL (Q20799) Probable calcium-binding mitochondrial carrier F55A11.4| Length = 588 Score = 54.3 bits (129), Expect = 2e-07 Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 4/161 (2%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYR--DISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 P D +K +QV+ SK + S +L E G+ F++G ++ + + A KF Y+ Sbjct: 268 PFDRIKVYLQVNSSKTNRLGVMSCLKLLHAEGGIKSFWRGNGINVIKIAPESAIKFMCYD 327 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG--FARCL 361 K+ G E + T L A ++A I+ + PME +K R+ + R + Sbjct: 328 QLKRLIQKKKGNEE---ISTFERLCAGSAAGAISQSTIYPMEVMKTRLALRKTGQLDRGI 384 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 K+ EG YKG +P IPY + A +ET+ Sbjct: 385 IHFAHKMYTKEGIRCFYKGYLPNLIGIIPYAGIDLAIYETL 425 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/139 (22%), Positives = 58/139 (41%), Gaps = 10/139 (7%) Frame = +2 Query: 98 EQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASA 277 ++G+ F+KG++ L+G YE K+ Y N+ + LA + Sbjct: 394 KEGIRCFYKGYLPNLIGIIPYAGIDLAIYETLKRTYVRYY-ETNSSEPGVLALLACGTCS 452 Query: 278 EVIADLALCPMEAVKVRIQTQPGFARCLTDGLPK----------LVRSEGAFGLYKGIVP 427 L+ P V+ R+Q A +T P+ ++++EG G Y+GI P Sbjct: 453 STCGQLSSYPFALVRTRLQ-----ALSITRYSPQPDTMFGQFKYILQNEGVTGFYRGITP 507 Query: 428 LWGRQIPYTMMKFACFETI 484 + + IP + + +E + Sbjct: 508 NFLKVIPAVSISYVVYEKV 526
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 53.9 bits (128), Expect = 3e-07 Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 6/169 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 + P + +KC +Q+ S KY L QE G+ G +KG + TL+ F Sbjct: 128 MTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYF 187 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG--F 349 YE+ K ++ + L L A A + P + +K R QT P + Sbjct: 188 MTYEWLKNIFTPEG--KRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKY 245 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 D L +L+R EG LYKG + R P F FE ++ + Sbjct: 246 PNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294
>ODC_RAT (Q99JD3) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 53.9 bits (128), Expect = 3e-07 Identities = 49/188 (26%), Positives = 81/188 (43%), Gaps = 17/188 (9%) Frame = +2 Query: 14 PLDLVKCNMQV-----DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 PLD+VK QV DP Y+ + F V+ + +GL GF+KG + ++ + + A KF Sbjct: 32 PLDVVKTRFQVQRSVTDPQSYKSLRDSFQVIFRTEGLFGFYKGIIPPILAETPKRAVKFS 91 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT------- 337 +E +KK ++ + + A + + + + P E VKV +Q Sbjct: 92 TFELYKKFLGYMSLSPG------LTFPIAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTE 145 Query: 338 QP---GFARCLTDGLPKLVRSE--GAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 QP +AR ++++ E G GL KG GR + M F + + K Sbjct: 146 QPSTFAYAR-------QIIKKEGWGFQGLNKGFTATLGRHGIFNMTYFGFYYNV-----K 193 Query: 503 HAVPKPKD 526 +P KD Sbjct: 194 DNIPSSKD 201
>AGC1_YEAST (Q12482) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 902 Score = 53.9 bits (128), Expect = 3e-07 Identities = 37/162 (22%), Positives = 73/162 (45%), Gaps = 6/162 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPS--KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V P+D +K MQ S +Y++ ++ +G+ G + G L+G + + A K Sbjct: 548 VYPIDFIKTRMQAQRSLAQYKNSIDCLLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTV 607 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA--- 352 ++ + +D G +L + + ASA + P+E VK+R+Q Q + Sbjct: 608 NDFMRNRLTDKNG-----KLSLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGEN 662 Query: 353 -RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 + + ++V+ G GLY G+ R +P++ + F + Sbjct: 663 IQQANETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTY 704 Score = 41.6 bits (96), Expect = 0.001 Identities = 44/182 (24%), Positives = 73/182 (40%), Gaps = 10/182 (5%) Frame = +2 Query: 14 PLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 PL++VK +QV + + ++++ GL G + G A L+ A F Sbjct: 644 PLEIVKIRLQVQSDYVGENIQQANETATQIVKKLGLRGLYNGVAACLMRDVPFSAIYFPT 703 Query: 182 YEYFKKCYSDIAGPENA--DRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR 355 Y + KK D + +RLKT L A A A + A P + +K R+Q P Sbjct: 704 YAHLKKDLFDFDPNDKTKRNRLKTWELLTAGAIAGMPAAFLTTPFDVIKTRLQIDPRKGE 763 Query: 356 CLTDGLPKLVRS----EGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPK 523 +G+ +R+ E +KG R P A +E ++K +P P Sbjct: 764 TKYNGIFHAIRTILKEESFRSFFKGGGARVLRSSPQFGFTLAAYE-----LFKGFIPSPD 818 Query: 524 DQ 529 ++ Sbjct: 819 NK 820
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 53.1 bits (126), Expect = 5e-07 Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 6/163 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDISSGF----GVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 + P + +KC +Q+ S ++ SG L QE G+ GF+KG TL+ F Sbjct: 128 MTPGERIKCLLQIQASSGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYF 187 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQP--GF 349 YE+ K ++ ++ L L A + + P + +K R QT P + Sbjct: 188 MTYEWLKNLFTPQG--KSVHDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGKY 245 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 D L +L+R EG LYKG + R P F FE Sbjct: 246 PNGFRDVLRELIREEGVTSLYKGFNAVMIRAFPANAACFLGFE 288 Score = 28.9 bits (63), Expect = 9.5 Identities = 23/65 (35%), Positives = 30/65 (46%), Gaps = 8/65 (12%) Frame = +2 Query: 305 PMEAVKVRIQT-------QPGFARCLTDGLPKLVRSEGAFGLYKGI-VPLWGRQIPYTMM 460 P++ VKVR+QT QP D K + EG GLY+G+ P+ G T M Sbjct: 30 PLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGLYRGMAAPIIG----VTPM 85 Query: 461 KFACF 475 CF Sbjct: 86 FAVCF 90
>MFRN1_HUMAN (Q9NYZ2) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 347 Score = 53.1 bits (126), Expect = 5e-07 Identities = 43/174 (24%), Positives = 71/174 (40%), Gaps = 4/174 (2%) Frame = +2 Query: 14 PLDLVKCNMQV---DP-SKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P+D VK MQ DP ++Y I +++ +G +G ++G A F Sbjct: 65 PVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFAC 124 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE K+ +D+ + L I A + A ++ D + P E VK R+Q R Sbjct: 125 YENMKRTLNDVFHHQGNSHLANGI---AGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSA 181 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPK 523 + + R+EG Y+ IP+ + F +E + E V H P+ Sbjct: 182 ISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQ 235
>DNC_MOUSE (Q9DAM5) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 318 Score = 52.8 bits (125), Expect = 6e-07 Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 15/184 (8%) Frame = +2 Query: 8 VXPLDLVKCNMQV--------DPS-KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 + PLD++K Q+ DP+ KY I +LQE+G F+KG + + Sbjct: 33 ISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGY 92 Query: 161 GACKF-GFYEYFKKCYSDIAGPENADRLKTVIYLA---ASASAEVIADLALCPMEAVKVR 328 GA +F F E + Y A+ +T + A + A L + P++ ++ R Sbjct: 93 GAVQFLAFEELTELLYQ-------ANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRTR 145 Query: 329 I--QTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 + Q +P L + + + ++EG F YKG+ P PY ++F+C+ ++ + Y Sbjct: 146 LAAQGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSL-KRAYD 204 Query: 503 HAVP 514 +P Sbjct: 205 WLIP 208 Score = 34.3 bits (77), Expect = 0.23 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 11/71 (15%) Frame = +2 Query: 14 PLDLVKCNMQVDP-----SKYRDISSGFGVL------LQEQGLGGFFKGWMATLVGYSSQ 160 PLDL+K +QV S + + S G+L LQE+G GFFKG +L+ + Sbjct: 236 PLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMKAALS 295 Query: 161 GACKFGFYEYF 193 F +YE F Sbjct: 296 TGFMFFWYELF 306
>GDC_HUMAN (P16260) Grave disease carrier protein (GDC) (Grave disease| autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 52.4 bits (124), Expect = 8e-07 Identities = 45/173 (26%), Positives = 74/173 (42%), Gaps = 6/173 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDIS--SGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V PLD VK +Q Y+ + S + Q++G G +KG A ++ GA +F Sbjct: 54 VAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMA 113 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 +E++K + G V L A + A + A + P++ V+VR+ Q Sbjct: 114 FEHYKTLITTKLGISGH-----VHRLMAGSMAGMTAVICTDPVDMVRVRLAFQVKGEHRY 168 Query: 362 TDGLPKL----VRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 T + + G FG Y+G++P PY + F F T+ + HA Sbjct: 169 TGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHA 221
>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1| Length = 695 Score = 52.4 bits (124), Expect = 8e-07 Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 7/163 (4%) Frame = +2 Query: 8 VXPLDLVKCNMQ-------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGA 166 V P+DLVK MQ + YR+ F +++ +G G ++G + L+G + + A Sbjct: 360 VYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLPQLMGVAPEKA 419 Query: 167 CKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG 346 K + + +D G + T + A A + P+E VK+R+Q Sbjct: 420 IKLTVNDLVRDKLTDKKG-----NIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGE 474 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 A +VR G FGLYKG R +P++ + F + Sbjct: 475 IASGSKIRAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPTY 517 Score = 43.5 bits (101), Expect = 4e-04 Identities = 45/170 (26%), Positives = 72/170 (42%), Gaps = 8/170 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGV----LLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 PL++VK +QV +I+SG + +++E GL G +KG A L+ A F Sbjct: 461 PLEIVKIRLQVAG----EIASGSKIRAWSVVRELGLFGLYKGARACLLRDVPFSAIYFPT 516 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC- 358 Y + K +D G + L LAA A A V A + P + +K R+Q + Sbjct: 517 YAHTKAMMADKDGYNHPLTL-----LAAGAIAGVPAASLVTPADVIKTRLQVVARSGQTT 571 Query: 359 ---LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 + D K++ EG +KG R P + +E + + Y Sbjct: 572 YTGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELLQRLFY 621
>M2OM_HUMAN (Q02978) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 51.6 bits (122), Expect = 1e-06 Identities = 44/164 (26%), Positives = 74/164 (45%), Gaps = 8/164 (4%) Frame = +2 Query: 8 VXPLDLVKCNMQV--DPSKYRDISSGFGVL---LQEQGLGGFFKGWMATLVGYSSQGACK 172 V PLDLVK MQ+ + +K R+ + F L L+ +GL G + G A L+ ++ + Sbjct: 38 VQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTR 97 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVI---ADLALCPMEAVKVRIQTQP 343 G Y + + G LK VI + A A+ + A++AL M A Q Sbjct: 98 LGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQR 157 Query: 344 GFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 + + + L ++ R EG L++G +P R + + A + Sbjct: 158 RGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASY 201 Score = 45.1 bits (105), Expect = 1e-04 Identities = 36/146 (24%), Positives = 66/146 (45%), Gaps = 6/146 (4%) Frame = +2 Query: 59 YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADR 238 Y+++ + + +E+G+ ++G + T+ A + Y K+ D + Sbjct: 160 YKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSD--- 216 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQT------QPGFARCLTDGLPKLVRSEGA 400 + + AS + ++ A P++ K RIQ +P + L D L K+VR EG Sbjct: 217 -NILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGL-DVLFKVVRYEGF 274 Query: 401 FGLYKGIVPLWGRQIPYTMMKFACFE 478 F L+KG P + R P+T++ F E Sbjct: 275 FSLWKGFTPYYARLGPHTVLTFIFLE 300
>CMC1_PONPY (Q5RBC8) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 51.6 bits (122), Expect = 1e-06 Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQ--------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P+DLVK MQ V Y++ F +L+ +G G ++G + L+G + + Sbjct: 343 AVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPE 402 Query: 161 GACKFGFYEYFKKCYS--DIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 A K ++ + ++ D + P A+ V+ + ++VI P+E VK+R+Q Sbjct: 403 KAIKLTVNDFVRDKFTRRDGSVPLPAE----VLAGGCAGGSQVIFTN---PLEIVKIRLQ 455 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 ++R G FGLYKG + R IP++ + F + Sbjct: 456 VAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVY 502 Score = 41.6 bits (96), Expect = 0.001 Identities = 44/170 (25%), Positives = 70/170 (41%), Gaps = 8/170 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGV----LLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 PL++VK +QV +I++G V +L++ G+ G +KG A + A F Sbjct: 446 PLEIVKIRLQVAG----EITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPV 501 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 Y + K +D G L LAA A A V A + P + +K R+Q + Sbjct: 502 YAHCKLLLADENGHVGGLNL-----LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTT 556 Query: 362 TDGL----PKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 G+ K++R EG +KG R P + +E + Y Sbjct: 557 YSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFY 606 Score = 37.0 bits (84), Expect = 0.035 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Frame = +2 Query: 155 SQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 ++GA + E ++ + P ++ + A + A+ P++ VK R+Q Sbjct: 296 AEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQ 355 Query: 335 TQPGFARCLT--------DGLPKLVRSEGAFGLYKGIVP 427 Q G + D K++R EG FGLY+G++P Sbjct: 356 NQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIP 394 Score = 31.2 bits (69), Expect = 1.9 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +2 Query: 8 VXPLDLVKCNMQV----DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 V P D++K +QV + Y + F +L+E+G F+KG A + S Q Sbjct: 536 VTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTL 595 Query: 176 GFYEYFKK-CYSDIAG 220 YE ++ Y D G Sbjct: 596 VTYELLQRWFYIDFGG 611
>CMC1_HUMAN (O75746) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 51.6 bits (122), Expect = 1e-06 Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 10/167 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQ--------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P+DLVK MQ V Y++ F +L+ +G G ++G + L+G + + Sbjct: 343 AVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPE 402 Query: 161 GACKFGFYEYFKKCYS--DIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 A K ++ + ++ D + P A+ V+ + ++VI P+E VK+R+Q Sbjct: 403 KAIKLTVNDFVRDKFTRRDGSVPLPAE----VLAGGCAGGSQVIFTN---PLEIVKIRLQ 455 Query: 335 TQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 ++R G FGLYKG + R IP++ + F + Sbjct: 456 VAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVY 502 Score = 42.7 bits (99), Expect = 6e-04 Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 8/170 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGV----LLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 PL++VK +QV +I++G V +L++ G+ G +KG A + A F Sbjct: 446 PLEIVKIRLQVAG----EITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPV 501 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 Y + K +D G L LAA A A V A + P + +K R+Q + Sbjct: 502 YAHCKLLLADENGHVGGLNL-----LAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTT 556 Query: 362 TDGL----PKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 G+ K++R EG +KG R P + A +E + Y Sbjct: 557 YSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLAHYEVLQRWFY 606 Score = 37.0 bits (84), Expect = 0.035 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Frame = +2 Query: 155 SQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 ++GA + E ++ + P ++ + A + A+ P++ VK R+Q Sbjct: 296 AEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQ 355 Query: 335 TQPGFARCLT--------DGLPKLVRSEGAFGLYKGIVP 427 Q G + D K++R EG FGLY+G++P Sbjct: 356 NQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIP 394 Score = 32.7 bits (73), Expect = 0.66 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +2 Query: 8 VXPLDLVKCNMQV----DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 V P D++K +QV + Y + F +L+E+G F+KG A + S Q Sbjct: 536 VTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTL 595 Query: 176 GFYEYFKK-CYSDIAG 220 YE ++ Y D G Sbjct: 596 AHYEVLQRWFYIDFGG 611
>MCAT_MACFA (Q8HXY2) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 51.2 bits (121), Expect = 2e-06 Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 6/169 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 + P + +KC +Q+ S KY L QE G+ G +KG + TL+ F Sbjct: 128 MTPGERIKCLLQIQASSGETKYTGTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYF 187 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQP--GF 349 YE+ K ++ + L L A A + P + +K R QT P + Sbjct: 188 MTYEWVKNIFTPEG--KRVSELSVPRVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKY 245 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 D L +L+ EG LYKG + R P F FE ++ + Sbjct: 246 PNGFRDVLRELIPDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294
>M2OM_BOVIN (P22292) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 50.8 bits (120), Expect = 2e-06 Identities = 38/146 (26%), Positives = 68/146 (46%), Gaps = 6/146 (4%) Frame = +2 Query: 59 YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADR 238 Y+++ + ++QE+G+ ++G + T+ A + Y K+ D + Sbjct: 160 YKNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSD--- 216 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQT------QPGFARCLTDGLPKLVRSEGA 400 + + AS + ++ A P++ VK RIQ +P + L D L K+VR EG Sbjct: 217 -NILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGL-DVLVKVVRYEGF 274 Query: 401 FGLYKGIVPLWGRQIPYTMMKFACFE 478 F L+KG P + R P+T++ F E Sbjct: 275 FSLWKGFTPYYARLGPHTVLTFIFLE 300 Score = 50.8 bits (120), Expect = 2e-06 Identities = 44/165 (26%), Positives = 80/165 (48%), Gaps = 9/165 (5%) Frame = +2 Query: 8 VXPLDLVKCNMQV--DPSKYRDISSGFGVL---LQEQGLGGFFKGWMATLVGYSSQGACK 172 V PLDLVK MQ+ + +K R+ + F L L+ +GL G + G A L+ ++ + Sbjct: 38 VQPLDLVKNRMQLSGEGAKTREYKTSFHALISILRAEGLRGIYTGLSAGLLRQATYTTTR 97 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVI---ADLALCPMEA-VKVRIQTQ 340 G Y + + G LK VI + A A+ + A++AL M A ++ + + Sbjct: 98 LGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPVDQR 157 Query: 341 PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 G+ + + + L ++V+ EG L++G +P R + + A + Sbjct: 158 RGY-KNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQLASY 201
>UCP5_MOUSE (Q9Z2B2) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 50.8 bits (120), Expect = 2e-06 Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 10/148 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS---------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGA 166 P+DL K +QV KYR + + +E+G+ + G L+ +S G Sbjct: 60 PVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSGIAPALLRQASYGT 119 Query: 167 CKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG 346 K G Y+ K+ + E + +I + + VI+ P + +K+R+Q Q Sbjct: 120 IKIGIYQSLKRLF-----VERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS 174 Query: 347 -FARCLTDGLPKLVRSEGAFGLYKGIVP 427 F + + + EG GL++G+VP Sbjct: 175 LFQGSMIGSFIDIYQQEGTRGLWRGVVP 202 Score = 49.7 bits (117), Expect = 5e-06 Identities = 42/164 (25%), Positives = 73/164 (44%), Gaps = 7/164 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSG-FGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 P D++K MQ S ++ G F + Q++G G ++G + T + + Y+ Sbjct: 161 PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220 Query: 191 FKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA------ 352 KK I D + T + +S + + LA P++ V+ R+ Q Sbjct: 221 TKKHL--IVSGMLGDTILT--HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLY 276 Query: 353 RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 + DG+ K+ + EG F LYKG P W R P+ ++ F +E + Sbjct: 277 KGTLDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQL 320
>YIA6_YEAST (P40556) Putative mitochondrial carrier YIL006W| Length = 373 Score = 50.8 bits (120), Expect = 2e-06 Identities = 41/155 (26%), Positives = 68/155 (43%), Gaps = 13/155 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSK-------YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 +AV PLD+ K +Q + YR I +++++G G +KG + ++GY Sbjct: 93 VAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPRGLYKGLVPIVLGYFPT 152 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 F YE+ KK + I P+ ++ + A A++ + + P+ VK R+ Q Sbjct: 153 WMIYFSVYEFSKKFFHGIF-PQFDFVAQSCAAITAGAASTTLTN----PIWVVKTRLMLQ 207 Query: 341 ------PGFARCLTDGLPKLVRSEGAFGLYKGIVP 427 P + D KL EG LY G+VP Sbjct: 208 SNLGEHPTHYKGTFDAFRKLFYQEGFKALYAGLVP 242 Score = 47.0 bits (110), Expect = 3e-05 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 7/85 (8%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQP-------GFARCLTDGLPKLVRSEGAF 403 T I + A A ++ +A+CP++ K R+Q Q + R + L +VR EG Sbjct: 77 TQITALSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPR 136 Query: 404 GLYKGIVPLWGRQIPYTMMKFACFE 478 GLYKG+VP+ P M+ F+ +E Sbjct: 137 GLYKGLVPIVLGYFPTWMIYFSVYE 161
>UCP5_HUMAN (O95258) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 50.4 bits (119), Expect = 3e-06 Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 10/148 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS---------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGA 166 P+DL K +QV KYR + + +E+G+ + G L+ +S G Sbjct: 60 PVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGT 119 Query: 167 CKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG 346 K G Y+ K+ + E + +I + + VI+ P + +K+R+Q Q Sbjct: 120 IKIGIYQSLKRLF-----VERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS 174 Query: 347 -FARCLTDGLPKLVRSEGAFGLYKGIVP 427 F + + + EG GL++G+VP Sbjct: 175 LFQGSMIGSFIDIYQQEGTRGLWRGVVP 202 Score = 50.1 bits (118), Expect = 4e-06 Identities = 42/164 (25%), Positives = 73/164 (44%), Gaps = 7/164 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSG-FGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 P D++K MQ S ++ G F + Q++G G ++G + T + + Y+ Sbjct: 161 PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDI 220 Query: 191 FKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA------ 352 KK I D + T + +S + + LA P++ V+ R+ Q Sbjct: 221 TKKHL--ILSGMMGDTILT--HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLY 276 Query: 353 RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 + DG+ K+ + EG F LYKG P W R P+ ++ F +E + Sbjct: 277 KGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQL 320
>GDC_BOVIN (Q01888) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) Length = 330 Score = 50.1 bits (118), Expect = 4e-06 Identities = 45/173 (26%), Positives = 74/173 (42%), Gaps = 6/173 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDIS--SGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V PLD VK +Q YR + S + +++G G +KG A ++ GA +F Sbjct: 52 VAPLDRVKVLLQAHNHHYRHLGVFSTLRAVPKKEGYLGLYKGNGAMMIRIFPYGAIQFMA 111 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 +E++K + G V L A + A + A + P++ V+VR+ Q Sbjct: 112 FEHYKTLITTKLGVSGH-----VHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHTY 166 Query: 362 TD---GLPKLVRSEGAF-GLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 T + EG F G Y+G++P PY + F F T+ + +A Sbjct: 167 TGIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYA 219 Score = 33.5 bits (75), Expect = 0.38 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 263 ASASAEVIADLALCPMEAVKVRIQTQPGFARCLT--DGLPKLVRSEGAFGLYKGIVPLWG 436 A A A + P++ VKV +Q R L L + + EG GLYKG + Sbjct: 40 AGGIAGCCAKTTVAPLDRVKVLLQAHNHHYRHLGVFSTLRAVPKKEGYLGLYKGNGAMMI 99 Query: 437 RQIPYTMMKFACFE 478 R PY ++F FE Sbjct: 100 RIFPYGAIQFMAFE 113
>CMC1_MOUSE (Q8BH59) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 677 Score = 50.1 bits (118), Expect = 4e-06 Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 8/165 (4%) Frame = +2 Query: 5 AVXPLDLVKCNMQ--------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P+DLVK MQ V Y++ F +L+ +G G ++G + L+G + + Sbjct: 343 AVYPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPE 402 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 A K ++ + ++ G + L I A + + P+E VK+R+Q Sbjct: 403 KAIKLTVNDFVRDKFTKRDG---SIPLPAEILAGGCAGGSQV--IFTNPLEIVKIRLQVA 457 Query: 341 PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 +++ G FGLYKG + R IP++ + F + Sbjct: 458 GEITTGPRVSALNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVY 502 Score = 37.0 bits (84), Expect = 0.035 Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Frame = +2 Query: 155 SQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 ++GA + E ++ + P ++ + A + A+ P++ VK R+Q Sbjct: 296 AEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQ 355 Query: 335 TQPGFARCLT--------DGLPKLVRSEGAFGLYKGIVP 427 Q G + D K++R EG FGLY+G++P Sbjct: 356 NQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIP 394 Score = 31.2 bits (69), Expect = 1.9 Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 5/76 (6%) Frame = +2 Query: 8 VXPLDLVKCNMQV----DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 V P D++K +QV + Y + F +L+E+G F+KG A + S Q Sbjct: 536 VTPADVIKTRLQVAARAGQTTYSGVVDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTL 595 Query: 176 GFYEYFKK-CYSDIAG 220 YE ++ Y D G Sbjct: 596 VTYELLQRWFYIDFGG 611
>CMC1_CAEEL (Q21153) Probable calcium-binding mitochondrial carrier K02F3.2| Length = 707 Score = 49.7 bits (117), Expect = 5e-06 Identities = 40/166 (24%), Positives = 76/166 (45%), Gaps = 9/166 (5%) Frame = +2 Query: 5 AVXPLDLVKCNMQ--------VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P+DLVK MQ V Y++ F +++ +GL G ++G + +VG + + Sbjct: 386 AVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLYRGLLPQIVGVAPE 445 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 A K +Y + ++ ++ + A + + + P+E VK+R+QT Sbjct: 446 KAIKLTMNDYMRDKFT------KDGKIPLYGEIIAGGTGGMCQVVFTNPLEIVKIRLQTA 499 Query: 341 PGFARC-LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 + G+ +++ G GLYKG + R IP++ + F + Sbjct: 500 GEVQQAGKKIGVFTVLKELGFLGLYKGSRACFLRDIPFSAIYFPAY 545 Score = 43.9 bits (102), Expect = 3e-04 Identities = 39/168 (23%), Positives = 69/168 (41%), Gaps = 6/168 (3%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGV--LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 PL++VK +Q + + GV +L+E G G +KG A + A F Y Sbjct: 488 PLEIVKIRLQT-AGEVQQAGKKIGVFTVLKELGFLGLYKGSRACFLRDIPFSAIYFPAYA 546 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTD 367 + K +D G + L ++A +A ++ P + +K R+Q + + Sbjct: 547 HAKLASADEDGMNSPGTLFASAFIAGVPAAGLVT-----PADVIKTRLQVAARAGQTTYN 601 Query: 368 GL----PKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 G+ KL++ EG L+KG R P + +E + + Y Sbjct: 602 GVIDCARKLIKEEGPMSLWKGTAARVCRSSPQFAVTLLTYEVLQRLFY 649
>ADT2_ANOGA (Q7PQV7) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 300 Score = 49.7 bits (117), Expect = 5e-06 Identities = 45/190 (23%), Positives = 83/190 (43%), Gaps = 17/190 (8%) Frame = +2 Query: 5 AVXPLDLVKCNMQV--------DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ + F + +EQG F++G +A ++ Y Sbjct: 27 AVAPIERVKLLLQVQHISKQIAEADRYKGMVDCFVRIPREQGFSAFWRGNLANVIRYFPT 86 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALC---PMEAVKVRI 331 A F F + +K+ + G + + T ++ AS + +LC P++ + R+ Sbjct: 87 QALNFAFKDKYKQVF---LGGVDKNTQFTRYFIGNLASGGMAGATSLCFVYPLDFARTRL 143 Query: 332 QTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEM 493 G + L D + K+ +++G GLY+G I Y F ++T M Sbjct: 144 AADVGKGAEAREFKGLGDCISKIFKTDGLVGLYRGFGVSVQGIIIYRAAYFGFYDTARGM 203 Query: 494 VYKHAVPKPK 523 +P PK Sbjct: 204 -----LPNPK 208
>M2OM_MOUSE (Q9CR62) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 49.3 bits (116), Expect = 7e-06 Identities = 43/164 (26%), Positives = 74/164 (45%), Gaps = 8/164 (4%) Frame = +2 Query: 8 VXPLDLVKCNMQV--DPSKYRDISSGFGVL---LQEQGLGGFFKGWMATLVGYSSQGACK 172 V PLDLVK MQ+ + +K R+ + F L L+ +GL G + G A L+ ++ + Sbjct: 38 VQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKTEGLKGIYTGLSAGLLRQATYTTTR 97 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVI---ADLALCPMEAVKVRIQTQP 343 G Y + + G LK +I + A A+ + A++AL M A Q Sbjct: 98 LGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGTPAEVALIRMTADGRLPADQR 157 Query: 344 GFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 + + + L ++ R EG L++G +P R + + A + Sbjct: 158 RGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASY 201 Score = 48.1 bits (113), Expect = 2e-05 Identities = 37/146 (25%), Positives = 67/146 (45%), Gaps = 6/146 (4%) Frame = +2 Query: 59 YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADR 238 Y+++ + + +E+G+ ++G + T+ A + Y K+ D + Sbjct: 160 YKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSD--- 216 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQT------QPGFARCLTDGLPKLVRSEGA 400 + + AS + ++ A P++ VK RIQ +P + L D L K+VR EG Sbjct: 217 -NILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGL-DVLLKVVRYEGF 274 Query: 401 FGLYKGIVPLWGRQIPYTMMKFACFE 478 F L+KG P + R P+T++ F E Sbjct: 275 FSLWKGFTPYYARLGPHTVLTFIFLE 300
>GDC_MOUSE (Q8C0K5) Grave disease carrier protein homolog (GDC) (Mitochondrial| solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 49.3 bits (116), Expect = 7e-06 Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 6/173 (3%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDIS--SGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V PLD VK +Q Y+ + S + Q++G G +KG A ++ GA +F Sbjct: 54 VAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMA 113 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC- 358 +E++K + G V L A + A + A + P++ V+VR+ Q Sbjct: 114 FEHYKTFITTKLGVSGH-----VHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTY 168 Query: 359 --LTDGLPKLVRSEGAF-GLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 + + EG F G Y+G++P PY + F F T+ + +A Sbjct: 169 SGIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYA 221 Score = 32.3 bits (72), Expect = 0.86 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Frame = +2 Query: 263 ASASAEVIADLALCPMEAVKVRIQTQPGFARCL--TDGLPKLVRSEGAFGLYKGIVPLWG 436 A A A + P++ VKV +Q + L L + + EG GLYKG + Sbjct: 42 AGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGNGAMMI 101 Query: 437 RQIPYTMMKFACFE 478 R PY ++F FE Sbjct: 102 RIFPYGAIQFMAFE 115
>DIF1_CAEEL (Q27257) Protein dif-1| Length = 312 Score = 48.9 bits (115), Expect = 9e-06 Identities = 47/172 (27%), Positives = 75/172 (43%), Gaps = 14/172 (8%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGV-----------LLQEQGLGGFFKGWMATLVG 148 + + P + +KC +QV + S+G GV L ++ G+ ++G ATL+ Sbjct: 120 IVMVPGERIKCLLQVQQAG----SAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLR 175 Query: 149 YSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALC-PMEAVKV 325 A YEY KK +S E A R + + IA+ +C P + +K Sbjct: 176 DIPASAAYLSVYEYLKKKFSG----EGAQRTLSPGATLMAGGLAGIANWGVCIPADVLKS 231 Query: 326 RIQTQP--GFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 R+QT P + + L +++R EG L+KG P+ R P ACF Sbjct: 232 RLQTAPEGKYPDGIRGVLREVLREEGPRALFKGFWPVMLRAFP---ANAACF 280 Score = 32.0 bits (71), Expect = 1.1 Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 9/53 (16%) Frame = +2 Query: 305 PMEAVKVRIQT--------QPGFARCLTDGLPKLVRSEGAFGLYKGI-VPLWG 436 P + VKVRIQT +P F L D + + V EG F LYKG+ PL G Sbjct: 24 PFDTVKVRIQTMPMPKPGEKPQFTGAL-DCVKRTVSKEGFFALYKGMAAPLVG 75 Score = 30.8 bits (68), Expect = 2.5 Identities = 40/169 (23%), Positives = 62/169 (36%), Gaps = 14/169 (8%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGF-GVL------LQEQGLGGFFKGWMATLVGYSSQGACK 172 P D VK +Q P F G L + ++G +KG A LVG S A Sbjct: 24 PFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGMAAPLVGVSPLFAVF 83 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA 352 FG K + + + + + A A A V + + P E +K +Q Q + Sbjct: 84 FGGCAVGKW----LQQTDPSQEMTFIQNANAGALAGVFTTIVMVPGERIKCLLQVQQAGS 139 Query: 353 RCL-------TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 D + KL + G +Y+G R IP + + +E Sbjct: 140 AGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIPASAAYLSVYE 188
>MFRN1_RAT (Q66H23) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 338 Score = 48.9 bits (115), Expect = 9e-06 Identities = 40/165 (24%), Positives = 67/165 (40%), Gaps = 4/165 (2%) Frame = +2 Query: 14 PLDLVKCNMQV---DP-SKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P+D VK MQ DP ++Y I ++ +G +G ++G A F Sbjct: 65 PVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFAC 124 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE K+ +D+ + L I A + A ++ D + P E VK R+Q + Sbjct: 125 YENMKRTLNDVFSHQGNSHLANGI---AGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSA 181 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 + + R+EG Y+ IP+ + F +E + E V Sbjct: 182 LSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQV 226 Score = 36.6 bits (83), Expect = 0.045 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 10/165 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P ++VK +Q+ S+++ S + + +GLG F++ + L + F YE+ Sbjct: 163 PAEVVKQRLQMYNSQHQSALSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 222 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTD-- 367 + + P ++ ++ + A +A A P++ K + TQ A L + Sbjct: 223 Q----EQVNPRRDYNPQS--HIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVS 276 Query: 368 ----GLPKLVRS----EGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 G+ R+ G G +KGI Q+P T + ++ +E Sbjct: 277 GRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYE 321 Score = 32.3 bits (72), Expect = 0.86 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 10/74 (13%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS----------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYS 154 A PLD+ K + + + +++ F + Q GL G+FKG A ++ Sbjct: 251 ATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQM 310 Query: 155 SQGACKFGFYEYFK 196 A + YE+FK Sbjct: 311 PSTAISWSVYEFFK 324
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrier-like protein| (Protein A BOUT DE SOUFFLE) (Carnitine/acylcarnitine translocase-like protein) (CAC-like protein) Length = 300 Score = 48.5 bits (114), Expect = 1e-05 Identities = 47/174 (27%), Positives = 66/174 (37%), Gaps = 19/174 (10%) Frame = +2 Query: 14 PLDLVKCNMQVDPS--------------KYRD-ISSGFGVLLQEQGLGGFFKGWMATLVG 148 P +L+KC +Q + KY + VL E G G FKG T Sbjct: 124 PTELIKCRLQAQGALAGASTTSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAR 183 Query: 149 YSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR 328 A F YE FK+ +AG + L + A A + P + VK Sbjct: 184 EVPGNATMFAAYEAFKRF---LAGGSDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSV 240 Query: 329 IQTQ----PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 +Q P + + D K+++SEG GLYKG P R +P F +E Sbjct: 241 LQVDDYKNPRYTGSM-DAFRKILKSEGVKGLYKGFGPAMARSVPANAACFLAYE 293 Score = 48.5 bits (114), Expect = 1e-05 Identities = 45/177 (25%), Positives = 65/177 (36%), Gaps = 22/177 (12%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 P D +K +Q P+ +Y + +G G +KG A L ++ A Sbjct: 24 PFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMGAPLATVAAFNAVL 83 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA 352 F + AG L A A A CP E +K R+Q Q A Sbjct: 84 FTVRGQMEGLLRSEAGVP----LTISQQFVAGAGAGFAVSFLACPTELIKCRLQAQGALA 139 Query: 353 RCLT--------------DGLPKLVRSE-GAFGLYKGIVPLWGRQIPYTMMKFACFE 478 T D ++RSE GA GL+KG+ P + R++P FA +E Sbjct: 140 GASTTSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYE 196
>MCATL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 306 Score = 48.5 bits (114), Expect = 1e-05 Identities = 45/164 (27%), Positives = 74/164 (45%), Gaps = 7/164 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSK---YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 P D+VK +QV ++ YR F +++++ + G +KG + L+G + A FG Sbjct: 21 PFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQ 80 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQP-GFARCL 361 + + P N A A+A I + CPME K R+Q Q G AR Sbjct: 81 GNTLRALGQDS-PLNQ--------FLAGAAAGAIQCVICCPMELAKTRLQLQAVGPARTY 131 Query: 362 ---TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 D L ++ R EG G+ +G+V R+ P + F ++ + Sbjct: 132 KGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVM 175 Score = 38.9 bits (89), Expect = 0.009 Identities = 40/167 (23%), Positives = 72/167 (43%), Gaps = 9/167 (5%) Frame = +2 Query: 14 PLDLVKCNMQ---VDPSK-YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P++L K +Q V P++ Y+ + + +GL G +G ++TL+ + FG Sbjct: 112 PMELAKTRLQLQAVGPARTYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPS----FGV 167 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-----PG 346 Y + G E DRL L A ++ + + L+ PM+ VK R+Q P Sbjct: 168 YFLTYDVMTRAMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPR 227 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIV 487 + R + D + + ++EG +G+ R P FA ++ Sbjct: 228 Y-RGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVL 273
>GDC_RAT (P16261) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) (Fragment) Length = 322 Score = 48.5 bits (114), Expect = 1e-05 Identities = 44/176 (25%), Positives = 77/176 (43%), Gaps = 9/176 (5%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDIS--SGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V PLD VK +Q Y+ + S + Q++G G +KG A ++ GA +F Sbjct: 54 VAPLDRVKVLLQAHNHHYKHLGVLSPLRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMA 113 Query: 182 YEYFKKCYSDIAGPE-NADRLKTVIYLAASASAEVIADLALC--PMEAVKVRIQTQPGFA 352 +E++K + G + RL +A S + ++ +C P++ V+VR+ Q Sbjct: 114 FEHYKTFITTKLGVSGHVHRL-----MAGSMAGKMSMTAVICTYPLDVVRVRLAFQVKGE 168 Query: 353 RC---LTDGLPKLVRSEGAF-GLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 + + EG F G Y+G++P PY + F F T+ + +A Sbjct: 169 HTYSGIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYASVSFFTFGTLKSVGLSYA 224 Score = 32.7 bits (73), Expect = 0.66 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 2/74 (2%) Frame = +2 Query: 263 ASASAEVIADLALCPMEAVKVRIQTQPGFARCL--TDGLPKLVRSEGAFGLYKGIVPLWG 436 A + A A + P++ VKV +Q + L L + + EG GLYKG + Sbjct: 42 AGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVLSPLRAVPQKEGYLGLYKGNGAMMI 101 Query: 437 RQIPYTMMKFACFE 478 R PY ++F FE Sbjct: 102 RIFPYGAIQFMAFE 115
>YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c| Length = 302 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/165 (24%), Positives = 70/165 (42%), Gaps = 6/165 (3%) Frame = +2 Query: 14 PLDLVKCNMQVDPSK---YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 P D VK +Q + Y + + + +GL F+KG + L+G + +F + Sbjct: 37 PFDCVKVRLQSQSNVSPIYNNALDCVKKISKNEGLAAFYKGTVLPLLGIGFCVSIQFTTF 96 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG---FAR 355 EY K+ +S P + Y + A + + + P+E V++R+Q Q G Sbjct: 97 EYCKRFFSRDGTPVTMPQ-----YYVSGAISGLANSFLVGPVEHVRIRLQIQTGKNVLYH 151 Query: 356 CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 D + K+ G G+ KG P R+ M F +E +V+ Sbjct: 152 GPWDCIKKISSQYGLSGIMKGYNPTAAREAHGLGMYFLAYEALVK 196 Score = 37.7 bits (86), Expect = 0.020 Identities = 44/173 (25%), Positives = 67/173 (38%), Gaps = 10/173 (5%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSK---YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 V P++ V+ +Q+ K Y + + GL G KG+ T + F Sbjct: 130 VGPVEHVRIRLQIQTGKNVLYHGPWDCIKKISSQYGLSGIMKGYNPTAAREAHGLGMYFL 189 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAA--SASAEVIADLALCPMEAVKVRIQTQPGFA 352 YE K + +A DR +T + A A LA P + VK +IQT GF Sbjct: 190 AYEALVK--NTMAKHHLTDRSQTPGWKLCVFGAGAGYAMWLAAYPFDIVKSKIQTD-GFL 246 Query: 353 RCLT-----DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 T + G G Y+G VP+ R P + F +ET+ + + Sbjct: 247 SKATYKNSWQCAKGIYTKAGLRGFYRGFVPVLVRAAPANAVTFYVYETVSQHI 299 Score = 30.8 bits (68), Expect = 2.5 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 4/62 (6%) Frame = +2 Query: 263 ASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGL---PKLVRSEGAFGLYKG-IVPL 430 A S V L P + VKVR+Q+Q + + L K+ ++EG YKG ++PL Sbjct: 23 AGVSGGVAQVLVGQPFDCVKVRLQSQSNVSPIYNNALDCVKKISKNEGLAAFYKGTVLPL 82 Query: 431 WG 436 G Sbjct: 83 LG 84
>OAC1_YEAST (P32332) Mitochondrial oxaloacetate transport protein| (Mitochondrial carrier protein PMT) Length = 324 Score = 48.1 bits (113), Expect = 2e-05 Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 9/171 (5%) Frame = +2 Query: 14 PLDLVKCNMQV--------DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 PL LVK +Q + + Y + +G + + +G+ G F+G A ++ + + Sbjct: 148 PLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSV 207 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG- 346 + Y K +I + + ++L AS + + + + P + + RI Q G Sbjct: 208 QLPIYNTAK----NILVKNDLMKDGPALHLTASTISGLGVAVVMNPWDVILTRIYNQKGD 263 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 + D L K VR EG LYKG R P+T+M E +++VY Sbjct: 264 LYKGPIDCLVKTVRIEGVTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVY 314
>MFRN1_MOUSE (Q920G8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 338 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/165 (23%), Positives = 67/165 (40%), Gaps = 4/165 (2%) Frame = +2 Query: 14 PLDLVKCNMQV---DP-SKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 P+D VK MQ DP ++Y I ++ +G +G ++G A F Sbjct: 65 PVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMMMGAGPAHAMYFAC 124 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE K+ +D+ + L + A + A ++ D + P E VK R+Q + Sbjct: 125 YENMKRTLNDVFSHQGNSHLANGV---AGSMATLLHDAVMNPAEVVKQRLQMYNSQHQSA 181 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 + + R+EG Y+ IP+ + F +E + E V Sbjct: 182 FSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQV 226 Score = 36.6 bits (83), Expect = 0.045 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 10/165 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P ++VK +Q+ S+++ S + + +GLG F++ + L + F YE+ Sbjct: 163 PAEVVKQRLQMYNSQHQSAFSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 222 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTD-- 367 + + P ++ ++ + A +A A P++ K + TQ A L + Sbjct: 223 Q----EQVNPRRDYNPQS--HIISGGLAGALAAAATTPLDVCKTLLNTQENMALSLANVS 276 Query: 368 ----GLPKLVRS----EGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 G+ R+ G G +KGI Q+P T + ++ +E Sbjct: 277 GRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYE 321 Score = 32.3 bits (72), Expect = 0.86 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 10/74 (13%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS----------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYS 154 A PLD+ K + + + +++ F + Q GL G+FKG A ++ Sbjct: 251 ATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQM 310 Query: 155 SQGACKFGFYEYFK 196 A + YE+FK Sbjct: 311 PSTAISWSVYEFFK 324
>COLT_DROME (Q9VQG4) Congested-like trachea protein| Length = 306 Score = 47.8 bits (112), Expect = 2e-05 Identities = 45/176 (25%), Positives = 73/176 (41%), Gaps = 12/176 (6%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSK-------YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 L+ PLD +K +Q P YR ++ +G+ G +KG A L G + Sbjct: 31 LSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPI 90 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 A F Y K+ E+A I++A S S + + L + P E +KV +QTQ Sbjct: 91 FAMCFAGYALGKRLQQR---GEDAKLTYPQIFVAGSFSG-LFSTLIMAPGERIKVLLQTQ 146 Query: 341 PGFA-----RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEM 493 G + D KL + G ++KG R +P + F +E + ++ Sbjct: 147 QGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDV 202 Score = 40.0 bits (92), Expect = 0.004 Identities = 40/166 (24%), Positives = 65/166 (39%), Gaps = 8/166 (4%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPS-----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGA 166 L + P + +K +Q KY + G L +E GL FKG AT++ Sbjct: 131 LIMAPGERIKVLLQTQQGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANG 190 Query: 167 CKFGFYEYFKKCYSDIA-GPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQP 343 F YE D+A ++ T + A A + + P + +K R+Q+ P Sbjct: 191 LYFLVYE----ALQDVAKSKSETGQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAP 246 Query: 344 --GFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 + + L+ +G LY+G+ P+ R P ACF Sbjct: 247 EGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFP---ANAACF 289
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 47.8 bits (112), Expect = 2e-05 Identities = 51/192 (26%), Positives = 86/192 (44%), Gaps = 18/192 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + R + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDK--RTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 + G A R L D L K+ +S+G GLY+G I Y F ++T Sbjct: 140 LAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTA-- 197 Query: 491 MVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ---KGMLPDPKN 206
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 47.8 bits (112), Expect = 2e-05 Identities = 51/192 (26%), Positives = 86/192 (44%), Gaps = 18/192 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + R + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDK--RTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 + G A R L D L K+ +S+G GLY+G I Y F ++T Sbjct: 140 LAADVGKAGAEREFRGLGDCLVKIYKSDGIRGLYQGFNVSVQGIIIYRAAYFGIYDTA-- 197 Query: 491 MVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ---KGMLPDPKN 206
>ADT_CHLKE (P31692) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 339 Score = 47.8 bits (112), Expect = 2e-05 Identities = 45/181 (24%), Positives = 77/181 (42%), Gaps = 15/181 (8%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS----------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYS 154 AV P++ VK +Q S +Y I + F + EQG+ F++G +A +V Y Sbjct: 58 AVAPIERVKLLLQTQDSNPMIKSGQVPRYTGIVNCFVRVSSEQGVASFWRGNLANVVRYF 117 Query: 155 SQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 A F F + K + + + R V+ LA+ A + L + P++ + R+ Sbjct: 118 PTQAFNFAFKDTIKGLFPKYSPKTDFWRF-FVVNLASGGLAGAGSLLIVYPLDFARTRLA 176 Query: 335 TQPGFARC-----LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 G + L D L K+V+ G LY+G I Y F ++T +++ Sbjct: 177 ADVGSGKSREFTGLVDCLSKVVKRGGPMALYQGFGVSVQGIIVYRGAYFGLYDTAKGVLF 236 Query: 500 K 502 K Sbjct: 237 K 237 Score = 30.8 bits (68), Expect = 2.5 Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 12/111 (10%) Frame = +2 Query: 212 IAGPEN--ADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLP--- 376 IA P+ AD + V L A +A I+ A+ P+E VK+ +QTQ + +P Sbjct: 28 IASPKETQADPMAFVKDLLAGGTAGAISKTAVAPIERVKLLLQTQDSNPMIKSGQVPRYT 87 Query: 377 -------KLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHA 508 ++ +G ++G + R P FA +TI + K++ Sbjct: 88 GIVNCFVRVSSEQGVASFWRGNLANVVRYFPTQAFNFAFKDTIKGLFPKYS 138
>ADT3_BOVIN (P32007) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) (ANT 2) Length = 297 Score = 47.4 bits (111), Expect = 3e-05 Identities = 50/192 (26%), Positives = 86/192 (44%), Gaps = 18/192 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + R + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDK--RTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 + G + R L D L K+ +S+G GLY+G I Y F ++T Sbjct: 140 LAADVGKSGSEREFRGLGDCLVKITKSDGIRGLYQGFNVSVQGIIIYRAAYFGIYDTA-- 197 Query: 491 MVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ---KGMLPDPKN 206
>SFC1_YEAST (P33303) Succinate/fumarate mitochondrial transporter (Regulator of| acetyl-CoA synthetase activity) Length = 322 Score = 47.4 bits (111), Expect = 3e-05 Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 21/189 (11%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISS-------GF----GVLLQEQGLGGFFKGWMATLVG 148 L PLD +K MQ+ YR ++ GF + Q++G +KG A ++G Sbjct: 26 LCCHPLDTIKVRMQI----YRRVAGIEHVKPPGFIKTGRTIYQKEGFLALYKGLGAVVIG 81 Query: 149 YSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR 328 + A +F YE+++ + E+ ++A + A L + PME VK+R Sbjct: 82 IIPKMAIRFSSYEFYRTL---LVNKESGIVSTGNTFVAGVGAGITEAVLVVNPMEVVKIR 138 Query: 329 IQTQ----------PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 +Q Q P + + +V+ EG LY+G+ RQ F + Sbjct: 139 LQAQHLTPSEPNAGPKYNNAI-HAAYTIVKEEGVSALYRGVSLTAARQATNQGANFTVYS 197 Query: 479 TIVEMVYKH 505 + E + + Sbjct: 198 KLKEFLQNY 206 Score = 30.8 bits (68), Expect = 2.5 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 7/69 (10%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGF-------GVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD +K +Q D S + SG LL+E+G +KG ++ + A Sbjct: 234 PLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLLKEEGFRALYKGITPRVMRVAPGQAVT 293 Query: 173 FGFYEYFKK 199 F YEY ++ Sbjct: 294 FTVYEYVRE 302
>GHC2_HUMAN (Q9H1K4) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 47.0 bits (110), Expect = 3e-05 Identities = 41/198 (20%), Positives = 79/198 (39%), Gaps = 28/198 (14%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSK--YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V P+DL K +Q K Y+ + + +G G ++G L + + A K Sbjct: 26 VFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAA 85 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ--------- 334 ++F++ + N + + A A + + CPME +K+++Q Sbjct: 86 NDFFRRLLMEDGMQRNLK-----MEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHH 140 Query: 335 ----TQPGFARCLTDGLP-------------KLVRSEGAFGLYKGIVPLWGRQIPYTMMK 463 + P +R T G +L+R++G GLY+G+ R IP++++ Sbjct: 141 QGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIY 200 Query: 464 FACFETIVEMVYKHAVPK 517 F F + + + K Sbjct: 201 FPLFANLNNLGFNELAGK 218
>TXTP_YEAST (P38152) Tricarboxylate transport protein (Citrate transport| protein) (CTP) Length = 299 Score = 47.0 bits (110), Expect = 3e-05 Identities = 36/151 (23%), Positives = 65/151 (43%), Gaps = 8/151 (5%) Frame = +2 Query: 101 QGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAE 280 QG+G + G A ++G +++ +F ++ K D E + + L A Sbjct: 64 QGIGSIYVGCPAFIIGNTAKAGIRFLGFDTIKDMLRDSETGELSGTRGVIAGLGAGLLES 123 Query: 281 VIADLALCPMEAVKVRI-----QTQPGF---ARCLTDGLPKLVRSEGAFGLYKGIVPLWG 436 V A + P EA+K + P + R + LVR +G GLY+G++P+ Sbjct: 124 VAA---VTPFEAIKTALIDDKQSATPKYHNNGRGVVRNYSSLVRDKGFSGLYRGVLPVSM 180 Query: 437 RQIPYTMMKFACFETIVEMVYKHAVPKPKDQ 529 RQ ++ C+ I ++ + PKD+ Sbjct: 181 RQAANQAVRLGCYNKIKTLIQDY-TDSPKDK 210 Score = 36.6 bits (83), Expect = 0.045 Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Frame = +2 Query: 14 PLDLVKCNMQ-VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 PLD VK MQ +D +KY + F + +E+GL F+KG L G F YE Sbjct: 234 PLDTVKTRMQSLDSTKYSSTMNCFATIFKEEGLKTFWKGATPRLGRLVLSGGIVFTIYE 292
>M2OM_RAT (P97700) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 46.6 bits (109), Expect = 4e-05 Identities = 42/164 (25%), Positives = 73/164 (44%), Gaps = 8/164 (4%) Frame = +2 Query: 8 VXPLDLVKCNMQV--DPSKYRDISSGFGVL---LQEQGLGGFFKGWMATLVGYSSQGACK 172 V PLDLV MQ+ + +K R+ + F L L+ +GL G + G A L+ ++ + Sbjct: 38 VQPLDLVXNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTR 97 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVI---ADLALCPMEAVKVRIQTQP 343 G Y + + G LK +I + A A+ + A++AL M A Q Sbjct: 98 LGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGPPAEVALIRMTADGRLPADQR 157 Query: 344 GFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 + + + L ++ R EG L++G +P R + + A + Sbjct: 158 RGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASY 201 Score = 45.4 bits (106), Expect = 1e-04 Identities = 36/146 (24%), Positives = 66/146 (45%), Gaps = 6/146 (4%) Frame = +2 Query: 59 YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADR 238 Y+++ + + +E+G+ ++G + T+ A + Y K+ D + Sbjct: 160 YKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSD--- 216 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQT------QPGFARCLTDGLPKLVRSEGA 400 + + A + ++ A P++ VK RIQ +P + L D L K+VR EG Sbjct: 217 -NILCHFCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKPEYKNGL-DVLLKVVRYEGF 274 Query: 401 FGLYKGIVPLWGRQIPYTMMKFACFE 478 F L+KG P + R P+T++ F E Sbjct: 275 FSLWKGFTPYYARLGPHTVLTFIFLE 300
>ADT3_HUMAN (P12236) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) Length = 297 Score = 46.6 bits (109), Expect = 4e-05 Identities = 49/192 (25%), Positives = 85/192 (44%), Gaps = 18/192 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDKHTQFWR--YFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 + G + R L D L K+ +S+G GLY+G I Y F ++T Sbjct: 140 LAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTA-- 197 Query: 491 MVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ---KGMLPDPKN 206
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 46.6 bits (109), Expect = 4e-05 Identities = 50/192 (26%), Positives = 86/192 (44%), Gaps = 18/192 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + R + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDK--RTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 + G A + L D L K+ +S+G GLY+G I Y F ++T Sbjct: 140 LAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTA-- 197 Query: 491 MVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ---KGMLPDPKN 206
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 46.6 bits (109), Expect = 4e-05 Identities = 50/192 (26%), Positives = 86/192 (44%), Gaps = 18/192 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + R + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDK--RTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 + G A + L D L K+ +S+G GLY+G I Y F ++T Sbjct: 140 LAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTA-- 197 Query: 491 MVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ---KGMLPDPKN 206
>YG2O_YEAST (P53257) Putative mitochondrial carrier YGR096W| Length = 314 Score = 46.6 bits (109), Expect = 4e-05 Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 23/152 (15%) Frame = +2 Query: 101 QGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLK---TVIYLAASA 271 +GL GFFKG +A++ + + FG YE + Y D A K + +A Sbjct: 162 EGLPGFFKGSIASMTTITLTASIMFGTYETIR-IYCDENEKTTAAHKKWELATLNHSAGT 220 Query: 272 SAEVIADLALCPMEAVKVRIQTQP--------------------GFARCLTDGLPKLVRS 391 VIA + P+E ++ R+Q GFAR GL ++++ Sbjct: 221 IGGVIAKIITFPLETIRRRMQFMNSKHLEKFSRHSSVYGSYKGYGFARI---GL-QILKQ 276 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETIV 487 EG LY+GI+ + IP T + F +ET + Sbjct: 277 EGVSSLYRGILVALSKTIPTTFVSFWGYETAI 308 Score = 31.2 bits (69), Expect = 1.9 Identities = 18/78 (23%), Positives = 37/78 (47%), Gaps = 5/78 (6%) Frame = +2 Query: 257 LAASASAEVIADLALCPMEAVKVRIQTQPG-----FARCLTDGLPKLVRSEGAFGLYKGI 421 L A A + ++A PM+ +K+R+Q P F + + ++++EG +KG Sbjct: 20 LLAGAVSGLLARSITAPMDTIKIRLQLTPANGLKPFGSQVMEVARSMIKNEGIRSFWKGN 79 Query: 422 VPLWGRQIPYTMMKFACF 475 +P + Y +F+ + Sbjct: 80 IPGSLLYVTYGSAQFSSY 97
>MRS3_YEAST (P10566) Mitochondrial RNA-splicing protein MRS3| Length = 314 Score = 46.2 bits (108), Expect = 6e-05 Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 3/159 (1%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKY---RDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 P+D +K +Q +K +++ S + +G +KG + ++G A FG Y Sbjct: 53 PIDALKTRIQSANAKSLSAKNMLSQISHISTSEGTLALWKGVQSVILGAGPAHAVYFGTY 112 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E+ KK D + + KT I + A A +D + P + +K RIQ + T Sbjct: 113 EFCKKNLIDSSDTQTHHPFKTAI---SGACATTASDALMNPFDTIKQRIQLNTSASVWQT 169 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFET 481 ++ +SEG Y IP+ F +E+ Sbjct: 170 --TKQIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYES 206
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 45.8 bits (107), Expect = 7e-05 Identities = 50/192 (26%), Positives = 86/192 (44%), Gaps = 18/192 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ + Sbjct: 24 AVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRHFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + R + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDK--RTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 + G A R L D L K+ +S+G GLY+G I Y F ++T Sbjct: 140 LAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTA-- 197 Query: 491 MVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ---KGMLPDPKN 206
>ADT_DROME (Q26365) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) (Stress sensitive B protein) Length = 312 Score = 45.8 bits (107), Expect = 7e-05 Identities = 50/195 (25%), Positives = 83/195 (42%), Gaps = 21/195 (10%) Frame = +2 Query: 5 AVXPLDLVKCNMQVD-------PSK-YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV P K Y+ + F + +EQG F++G +A ++ Y Sbjct: 40 AVAPIERVKLLLQVQHISKQISPDKQYKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPT 99 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + + Y A + AS +LC P++ + R Sbjct: 100 QALNFAFKDKYKQVF--LGGVDKNTQFWR--YFAGNLASGGAAGATSLCFVYPLDFARTR 155 Query: 329 IQTQ---------PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFET 481 + G CLT K+ +S+G GLY+G I Y F ++T Sbjct: 156 LAADTGKGGQREFTGLGNCLT----KIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDT 211 Query: 482 IVEMVYKHAVPKPKD 526 M +P PK+ Sbjct: 212 ARGM-----LPDPKN 221
>DIC_HUMAN (Q9UBX3) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/66 (33%), Positives = 39/66 (59%) Frame = +2 Query: 305 PMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 P++ +KV +QTQ +T ++VR++G LY G+ RQ+ Y++ +FA +ET+ Sbjct: 26 PLDLLKVHLQTQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETV 85 Query: 485 VEMVYK 502 + V K Sbjct: 86 RDRVAK 91 Score = 36.2 bits (82), Expect = 0.059 Identities = 44/168 (26%), Positives = 70/168 (41%), Gaps = 11/168 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC- 169 P DLV MQ D Y G + +E+GL F G AT+ SS+GA Sbjct: 119 PADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSG--ATMA--SSRGALV 174 Query: 170 ---KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 + Y+ K+ ++ +D + T + AS A A P++ +K R+ Sbjct: 175 TVGQLSCYDQAKQLV--LSTGYLSDNIFT--HFVASFIAGGCATFLCQPLDVLKTRLMNS 230 Query: 341 PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 G + + + + G YKG+VP R IP+T++ F E + Sbjct: 231 KGEYQGVFHCAVETAKL-GPLAFYKGLVPAGIRLIPHTVLTFVFLEQL 277 Score = 32.3 bits (72), Expect = 0.86 Identities = 34/169 (20%), Positives = 67/169 (39%), Gaps = 8/169 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 PLDL+K ++Q ++ +++ G+ + G A+L + +F YE Sbjct: 26 PLDLLKVHLQTQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETV 85 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT--------QPGF 349 + D + L + + + + P + V VR+Q + + Sbjct: 86 R----DRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNY 141 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 A L DGL ++ R EG L+ G R T+ + +C++ ++V Sbjct: 142 AHAL-DGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLV 189
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor| Length = 307 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVI---YL 259 LL +G GF+KG + L+G + + +FG E K+ + NAD T+ Y Sbjct: 69 LLANEGPRGFYKGTLTPLIGVGACVSLQFGVNEAMKRFFHH----RNADMSSTLSLPQYY 124 Query: 260 AASASAEVIADLALCPMEAVKVRIQTQPG 346 A + ++ P+E V++R+QTQ G Sbjct: 125 ACGVTGGIVNSFLASPIEHVRIRLQTQTG 153 Score = 36.6 bits (83), Expect = 0.045 Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVD----PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 L V PLD++K MQ D P ISS L G+G FFKG+ T++ + Sbjct: 235 LMVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGA 294 Query: 170 KFGFYE 187 F +E Sbjct: 295 TFATFE 300 Score = 30.0 bits (66), Expect = 4.3 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Frame = +2 Query: 233 DRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLY 412 D + V L A + + L P + KVR+QT + + + KL+ +EG G Y Sbjct: 21 DNARVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQTSSTPTTAM-EVVRKLLANEGPRGFY 79 Query: 413 KG-IVPLWG 436 KG + PL G Sbjct: 80 KGTLTPLIG 88
>YHM1_YEAST (P38988) Putative mitochondrial carrier protein YHM1/SHM1| Length = 300 Score = 44.7 bits (104), Expect = 2e-04 Identities = 35/166 (21%), Positives = 71/166 (42%), Gaps = 4/166 (2%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 + + PLD++K Q +P ++ GF +L+++GL ++GW T + FG Sbjct: 134 IVLLPLDVLKIKRQTNPESFK--GRGFIKILRDEGLFNLYRGWGWTAARNAPGSFALFGG 191 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ----PGF 349 + K+ + A + I A + +I P++ +K RIQ + P Sbjct: 192 NAFAKEYILGLKDYSQATWSQNFISSIVGACSSLIVS---APLDVIKTRIQNRNFDNPES 248 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIV 487 + + +++EG +KG+ P P + FA ++++ Sbjct: 249 GLRI---VKNTLKNEGVTAFFKGLTPKLLTTGPKLVFSFALAQSLI 291
>PET8_YEAST (P38921) Putative mitochondrial carrier protein PET8| Length = 284 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/171 (25%), Positives = 70/171 (40%), Gaps = 12/171 (7%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 L P+D +K +Q G G G ++G + +V + + F Sbjct: 20 LVFFPIDTIKTRLQAK-----------GGFFANGGYKGIYRGLGSAVVASAPGASLFFIS 68 Query: 182 YEYFK--------KCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT 337 Y+Y K K YS G E + T ++ +S+ E+ A L P E VK R Q Sbjct: 69 YDYMKVKSRPYISKLYSQ--GSEQL--IDTTTHMLSSSIGEICACLVRVPAEVVKQRTQV 124 Query: 338 QPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWG----RQIPYTMMKFACFE 478 + T L ++R++ GL K + W R+IP+T ++F +E Sbjct: 125 HSTNSSWQT--LQSILRNDNKEGLRKNLYRGWSTTIMREIPFTCIQFPLYE 173 Score = 35.0 bits (79), Expect = 0.13 Identities = 25/103 (24%), Positives = 43/103 (41%) Frame = +2 Query: 119 FKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLA 298 ++GW T++ +F YEY KK ++ G + K I + A IA Sbjct: 151 YRGWSTTIMREIPFTCIQFPLYEYLKKTWAKANGQSQVEPWKGAI---CGSIAGGIAAAT 207 Query: 299 LCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVP 427 P++ +K R+ A L + ++ R EG + G+ P Sbjct: 208 TTPLDFLKTRLMLNKTTA-SLGSVIIRIYREEGPAVFFSGVGP 249
>MFRN_DROME (Q9VAY3) Mitoferrin| Length = 379 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/161 (22%), Positives = 65/161 (40%), Gaps = 2/161 (1%) Frame = +2 Query: 2 LAVXPLDLVKCNMQV--DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 + + PLD VK MQ P+K +I S ++ +GL +G A ++G + F Sbjct: 30 VVMYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITREGLLRPIRGASAVVLGAGPAHSLYF 89 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR 355 YE K+ + N + Y+ + A A +I D P + +K R+Q Sbjct: 90 AAYEMTKELTAKFTSVRNLN------YVISGAVATLIHDAISSPTDVIKQRMQMYNSPYT 143 Query: 356 CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFE 478 + + + + EG Y+ +PY + F +E Sbjct: 144 SVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYE 184
>UCP1_HUMAN (P25874) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 44.7 bits (104), Expect = 2e-04 Identities = 37/164 (22%), Positives = 72/164 (43%), Gaps = 7/164 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPS------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 P ++VK +Q +Y + + ++ +GL G +KG L+ + Sbjct: 133 PTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTEL 192 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGFA 352 Y+ K+ + + AD + +L ++ A A P++ VK R I + PG Sbjct: 193 VTYDLMKEAF--VKNNILADDVPC--HLVSALIAGFCATAMSSPVDVVKTRFINSPPGQY 248 Query: 353 RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 + + + K+ +EG +KG+VP + R + ++ F CFE + Sbjct: 249 KSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQL 292 Score = 38.5 bits (88), Expect = 0.012 Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 13/179 (7%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD K +QV +Y+ + +++ +G + G A L S + + Sbjct: 33 PLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLR 92 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQP--- 343 G Y+ ++ + AG E A L + I + +A P E VKVR+Q Q Sbjct: 93 IGLYDTVQEFLT--AGKETAPSLGSKILAGLTTGG--VAVFIGQPTEVVKVRLQAQSHLH 148 Query: 344 GFARCLT---DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAV 511 G T + + +EG GL+KG P R + + ++ + E K+ + Sbjct: 149 GIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNI 207 Score = 36.2 bits (82), Expect = 0.059 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 10/92 (10%) Frame = +2 Query: 251 IYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPK----------LVRSEGA 400 + L ++ A +AD+ P++ KVR+Q Q C T + + +V++EG Sbjct: 15 VQLFSAGIAACLADVITFPLDTAKVRLQVQ---GECPTSSVIRYKGVLGTITAVVKTEGR 71 Query: 401 FGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 LY G+ RQI ++ ++T+ E + Sbjct: 72 MKLYSGLPAGLQRQISSASLRIGLYDTVQEFL 103
>MCATL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 303 Score = 44.7 bits (104), Expect = 2e-04 Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 7/164 (4%) Frame = +2 Query: 14 PLDLVKCNMQV---DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 P D VK +QV + +YR F +++++ + G +KG + L+G + A FG Sbjct: 21 PFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQ 80 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-PGFARCL 361 + + P N A A+A I + CPME K R+Q Q G AR Sbjct: 81 GNTLRALGHDS-PLNQ--------FLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTY 131 Query: 362 ---TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 D L ++ EG G+ +G+V R+ P + F ++ + Sbjct: 132 KGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDAL 175 Score = 40.0 bits (92), Expect = 0.004 Identities = 41/167 (24%), Positives = 70/167 (41%), Gaps = 9/167 (5%) Frame = +2 Query: 14 PLDLVKCNMQV-DPSKYRDISSGFGVLLQ---EQGLGGFFKGWMATLVGYSSQGACKFGF 181 P++L K +Q+ D R L Q +GL G +G ++TL+ + FG Sbjct: 112 PMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPS----FGV 167 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-----PG 346 Y + G E DRL L A ++ +++ L+ P++ VK R+Q P Sbjct: 168 YFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPR 227 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIV 487 + R + D + + R+EG +G+ R P FA ++ Sbjct: 228 Y-RGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVL 273
>ADT1_RAT (Q05962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) Length = 297 Score = 44.3 bits (103), Expect = 2e-04 Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 19/193 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTV-IYLAAS-ASAEVIADLALC---PMEAVKV 325 A F F + +K+ + DR K Y A + AS +LC P++ + Sbjct: 84 QALNFAFKDKYKQIFLG-----GVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFART 138 Query: 326 RIQTQPGFARC------LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIV 487 R+ G L D L K+ +S+G GLY+G I Y F ++T Sbjct: 139 RLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTA- 197 Query: 488 EMVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ----KGMLPDPKN 206
>ADT1_MOUSE (P48962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (mANC1) Length = 297 Score = 44.3 bits (103), Expect = 2e-04 Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 19/193 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTV-IYLAAS-ASAEVIADLALC---PMEAVKV 325 A F F + +K+ + DR K Y A + AS +LC P++ + Sbjct: 84 QALNFAFKDKYKQIFLG-----GVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFART 138 Query: 326 RIQTQPGFARC------LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIV 487 R+ G L D L K+ +S+G GLY+G I Y F ++T Sbjct: 139 RLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTA- 197 Query: 488 EMVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ----KGMLPDPKN 206
>UCP3_MOUSE (P56501) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/172 (23%), Positives = 66/172 (38%), Gaps = 9/172 (5%) Frame = +2 Query: 14 PLDLVKCNMQV-------DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 P D+VK Q KYR + + +E+G+ G +KG + + + Sbjct: 133 PTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAE 192 Query: 173 FGFYEYFK-KCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQP-G 346 Y+ K K +N + ++ A A + P++ VK R P G Sbjct: 193 MVTYDIIKEKLLESHLFTDNFP-----CHFVSAFGAGFCATVVASPVDVVKTRYMNAPLG 247 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 R + K+V EG YKG VP + R + +M F +E + + K Sbjct: 248 RYRSPLHCMLKMVAQEGPTAFYKGFVPSFLRLGAWNVMMFVTYEQLKRALMK 299 Score = 38.5 bits (88), Expect = 0.012 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 7/104 (6%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ---PGFA----RCLTDGLPKLVRSEGAF 403 TV+ + +A ADL P++ KVR+Q Q PG R + + +VR+EG Sbjct: 13 TVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGAQSVQYRGVLGTILTMVRTEGPR 72 Query: 404 GLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 Y G+V RQ+ + ++ ++++ + PK D S Sbjct: 73 SPYSGLVAGLHRQMSFASIRIGLYDSVKQFY----TPKGADHSS 112
>UCP3_CANFA (Q9N2I9) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 43.9 bits (102), Expect = 3e-04 Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 8/171 (4%) Frame = +2 Query: 14 PLDLVKCNMQVD-------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 P D+VK Q KY + + +E+G+ G +KG + + + + Sbjct: 136 PTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTLPNITRNAIVNCAE 195 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA 352 Y+ K+ D + + A A V+A P++ VK R P Sbjct: 196 MVTYDIIKEKLLDYHLLTDNFPCHLISAFGAGFCATVVAS----PVDVVKTRYMNSPPGQ 251 Query: 353 RCLT-DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 C D + K+V EG YKG P + R + ++ F +E + + K Sbjct: 252 YCSPLDCMLKMVTQEGPTAFYKGFTPSFLRLGTWNVVMFVTYEQLKRALMK 302 Score = 33.5 bits (75), Expect = 0.38 Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 10/107 (9%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFA----------RCLTDGLPKLVRSE 394 T + + +A ADL P++ KVR+Q Q R + + +VR+E Sbjct: 13 TAVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENQATQAARRIQYRGVLGTILTMVRTE 72 Query: 395 GAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 G Y G+V RQ+ + ++ ++++ + PK D S Sbjct: 73 GPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFY----TPKGSDHSS 115
>GHC2_MOUSE (Q9DB41) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) (Fragment) Length = 312 Score = 43.9 bits (102), Expect = 3e-04 Identities = 40/190 (21%), Positives = 75/190 (39%), Gaps = 28/190 (14%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSK--YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V P+DL K +Q K YR ++ + +G G ++G L + + A K Sbjct: 23 VFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAA 82 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC- 358 ++ ++ N + + A A + + CPME +K+++Q A C Sbjct: 83 NDFLRQLLMQDGTQRNLK-----MEMLAGCGAGICQVVITCPMEMLKIQLQDAGRLAVCH 137 Query: 359 ------------------LTDGLP-------KLVRSEGAFGLYKGIVPLWGRQIPYTMMK 463 T P +L+R++G GLY+G+ R IP++++ Sbjct: 138 QASASATPTSRPYSTGSTSTHRRPSATLIARELLRTQGLSGLYRGLGATLLRDIPFSIIY 197 Query: 464 FACFETIVEM 493 F F + ++ Sbjct: 198 FPLFANLNQL 207 Score = 34.3 bits (77), Expect = 0.23 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 12/128 (9%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS 268 LL+ QGL G ++G ATL+ F + + + E + A Sbjct: 170 LLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANL----NQLGVSELTGKASFTHSFVAG 225 Query: 269 ASAEVIADLALCPMEAVKVRIQT-QPGFAR----CLTDGLPKLVRSEGAFGLYKG----- 418 +A +A +A+ P++ +K RIQT + G +TD KL EG KG Sbjct: 226 CTAGSVAAVAVTPLDVLKTRIQTLKKGLGEDTYSGVTDCARKLWTQEGPAAFMKGAGCRA 285 Query: 419 --IVPLWG 436 I PL+G Sbjct: 286 LVIAPLFG 293 Score = 34.3 bits (77), Expect = 0.23 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = +2 Query: 275 AEVIADLALCPMEAVKVRIQTQPG--FARCLTDGLPKLVRSEGAFGLYKG 418 A ++ + P++ K R+Q Q G R +TD L K R+EG G+Y+G Sbjct: 15 AGLVGVTCVFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARAEGFLGMYRG 64
>UCP3_RAT (P56499) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 43.9 bits (102), Expect = 3e-04 Identities = 40/171 (23%), Positives = 67/171 (39%), Gaps = 8/171 (4%) Frame = +2 Query: 14 PLDLVKCNMQV-------DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 P D+VK Q KYR + + +E+G+ G +KG + + + Sbjct: 133 PTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAE 192 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGF 349 Y+ K+ D + V A A V+A P++ VK R + PG Sbjct: 193 MVTYDIIKEKLLDSHLFTDNFPCHFVSAFGAGFCATVVAS----PVDVVKTRYMNAPPGR 248 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 R + ++V EG YKG +P + R + +M F +E + + K Sbjct: 249 YRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQLKRALMK 299 Score = 38.9 bits (89), Expect = 0.009 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 7/104 (6%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ---PGFA----RCLTDGLPKLVRSEGAF 403 TV+ + +A ADL P++ KVR+Q Q PG R + + +VR+EG Sbjct: 13 TVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGVQSVQYRGVLGTILTMVRTEGPR 72 Query: 404 GLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 Y G+V RQ+ + ++ ++++ + PK D S Sbjct: 73 SPYSGLVAGLHRQMSFASIRIGLYDSVKQFY----TPKGTDHSS 112
>DIC_MOUSE (Q9QZD8) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 43.5 bits (101), Expect = 4e-04 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 7/87 (8%) Frame = +2 Query: 263 ASASAEVIADLALC-------PMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGI 421 A AS LA C P++ +KV +QTQ +T ++VR++G LY G+ Sbjct: 4 ARASRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGL 63 Query: 422 VPLWGRQIPYTMMKFACFETIVEMVYK 502 RQ+ Y++ +FA +ET+ + + K Sbjct: 64 SASLCRQMTYSLTRFAIYETMRDYMTK 90 Score = 30.8 bits (68), Expect = 2.5 Identities = 43/168 (25%), Positives = 73/168 (43%), Gaps = 11/168 (6%) Frame = +2 Query: 14 PLDLVKCNMQVD----PSKYRDIS---SGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC- 169 P DLV MQ D PS+ R+ S G + +E+ L F G AT+ SS+GA Sbjct: 118 PADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSG--ATMA--SSRGALV 173 Query: 170 ---KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 + Y+ K+ ++ +D + T + +S A A P++ +K R+ Sbjct: 174 TVGQLSCYDQAKQLV--LSTGYLSDNIFT--HFVSSFIAGGCATFLCQPLDVLKTRLMNS 229 Query: 341 PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 G + + + + G +KG+ P R IP+T++ F E + Sbjct: 230 KGEYQGVFHCAMETAKL-GPQAFFKGLFPAGIRLIPHTVLTFMFLEQL 276 Score = 30.4 bits (67), Expect = 3.3 Identities = 35/169 (20%), Positives = 65/169 (38%), Gaps = 8/169 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 PLDL+K ++Q ++ +++ G + G A+L + +F YE Sbjct: 25 PLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETM 84 Query: 194 KKCYS-DIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ----PGFARC 358 + + D GP L + + + P + V VR+Q P R Sbjct: 85 RDYMTKDSQGP-----LPFYNKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRN 139 Query: 359 LT---DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 + DGL ++ R E L+ G R T+ + +C++ ++V Sbjct: 140 YSHALDGLYRVAREESLRKLFSGATMASSRGALVTVGQLSCYDQAKQLV 188
>ADT2_ARATH (P40941) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 385 Score = 43.5 bits (101), Expect = 4e-04 Identities = 35/164 (21%), Positives = 73/164 (44%), Gaps = 9/164 (5%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I FG ++++G+G ++G A ++ Y A F F +YFK+ Sbjct: 117 EMLKAGRLTEP--YKGIRDCFGRTIRDEGIGSLWRGNTANVIRYFPTQALNFAFKDYFKR 174 Query: 200 CYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR-------- 355 + + ++ LA+ +A + L + ++ + R+ A+ Sbjct: 175 LF-NFKKDKDGYWKWFAGNLASGGAAGASSLLFVYSLDYARTRLANDSKSAKKGGGERQF 233 Query: 356 -CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 L D K ++S+G GLY+G I Y + F ++++ Sbjct: 234 NGLVDVYKKTLKSDGIAGLYRGFNISCAGIIVYRGLYFGLYDSV 277 Score = 30.8 bits (68), Expect = 2.5 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%) Frame = +2 Query: 92 LQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASA 271 L+ G+ G ++G+ + G FG Y+ K + G + A+ A Sbjct: 244 LKSDGIAGLYRGFNISCAGIIVYRGLYFGLYDSVKPVL--LTGDLQDS------FFASFA 295 Query: 272 SAEVI---ADLALCPMEAVKVRIQTQPGFA---RCLTDGLPKLVRSEGAFGLYKG 418 +I A LA P++ V+ R+ G A + D ++V+ EGA L+KG Sbjct: 296 LGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSFDAFSQIVKKEGAKSLFKG 350
>UCP3_HUMAN (P55916) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 312 Score = 43.5 bits (101), Expect = 4e-04 Identities = 41/172 (23%), Positives = 70/172 (40%), Gaps = 9/172 (5%) Frame = +2 Query: 14 PLDLVKCNMQVD----PS----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 P D+VK Q PS KY + + +E+G+ G +KG + ++ + Sbjct: 136 PTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195 Query: 170 KFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPG 346 + Y+ K+ D + V A A V+A P++ VK R + + PG Sbjct: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVAS----PVDVVKTRYMNSPPG 251 Query: 347 FARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 D + K+V EG YKG P + R + ++ F +E + + K Sbjct: 252 QYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRALMK 303 Score = 35.4 bits (80), Expect = 0.10 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 10/115 (8%) Frame = +2 Query: 221 PENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPK------- 379 P + V +L A +A ADL P++ KVR+Q Q T L + Sbjct: 6 PSDVPPTMAVKFLGAGTAA-CFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGT 64 Query: 380 ---LVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 +VR+EG Y G+V RQ+ + ++ +++ V+ VY PK D S Sbjct: 65 ILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDS-VKQVY---TPKGADNSS 115
>DIC1_CANGA (Q6FTN2) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) Length = 295 Score = 43.5 bits (101), Expect = 4e-04 Identities = 24/84 (28%), Positives = 42/84 (50%) Frame = +2 Query: 272 SAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPY 451 +A + A + P++ KVR+Q P + L ++++EG GLY G+ RQ Y Sbjct: 15 AAGIFAVMNTHPLDLTKVRLQAAPIPKPTIVQMLRSILKNEGIVGLYAGLSASLLRQCTY 74 Query: 452 TMMKFACFETIVEMVYKHAVPKPK 523 T +F ++ + E H +P+ K Sbjct: 75 TTARFGMYDALKE----HVIPRDK 94
>ADT3_PIG (Q6QRN9) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) Length = 297 Score = 42.7 bits (99), Expect = 6e-04 Identities = 40/156 (25%), Positives = 73/156 (46%), Gaps = 18/156 (11%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG+ F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS-ASAEVIADLALC---PMEAVKVR 328 A F F + +K+ + + G + + Y A + AS +LC P++ + R Sbjct: 84 QALNFAFKDKYKQIF--LGGVDKHTQFWR--YFAGNLASGGAAGATSLCFVYPLDFARTR 139 Query: 329 IQTQPGFA------RCLTDGLPKLVRSEGAFGLYKG 418 + G + + L D L K+ +S+G GLY+G Sbjct: 140 LAADVGKSATEREFKGLGDCLVKITKSDGIRGLYQG 175
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 42.7 bits (99), Expect = 6e-04 Identities = 50/197 (25%), Positives = 81/197 (41%), Gaps = 23/197 (11%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTV-IYLAAS-ASAEVIADLALC---PMEAVKV 325 A F F + +K+ + DR K Y A + AS +LC P++ + Sbjct: 84 QALNFAFKDKYKQIFLG-----GVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFART 138 Query: 326 RIQTQ----------PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 R+ G CLT K+ +S+G GLY+G I Y F + Sbjct: 139 RLAADVGKGAAQREFSGLGNCLT----KIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVY 194 Query: 476 ETIVEMVYKHAVPKPKD 526 +T K +P PK+ Sbjct: 195 DTA-----KGMLPDPKN 206
>ADT1_HUMAN (P12235) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) Length = 297 Score = 42.7 bits (99), Expect = 6e-04 Identities = 49/193 (25%), Positives = 81/193 (41%), Gaps = 19/193 (9%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTV-IYLAAS-ASAEVIADLALC---PMEAVKV 325 A F F + +K+ + DR K Y A + AS +LC P++ + Sbjct: 84 QALNFAFKDKYKQLFLG-----GVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFART 138 Query: 326 RIQTQPGFARC------LTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIV 487 R+ G L D + K+ +S+G GLY+G I Y F ++T Sbjct: 139 RLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTA- 197 Query: 488 EMVYKHAVPKPKD 526 K +P PK+ Sbjct: 198 ----KGMLPDPKN 206
>DIC1_YEAST (Q06143) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) (DTP) Length = 298 Score = 42.7 bits (99), Expect = 6e-04 Identities = 23/75 (30%), Positives = 38/75 (50%) Frame = +2 Query: 272 SAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPY 451 +A + A + P++ KVR+Q P L L ++ +EG GLY G+ RQ Y Sbjct: 22 AAGIFATMVTHPLDLAKVRLQAAPMPKPTLFRMLESILANEGVVGLYSGLSAAVLRQCTY 81 Query: 452 TMMKFACFETIVEMV 496 T ++F ++ + E V Sbjct: 82 TTVRFGAYDLLKENV 96
>UCP3_PIG (O97649) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 42.7 bits (99), Expect = 6e-04 Identities = 39/171 (22%), Positives = 68/171 (39%), Gaps = 8/171 (4%) Frame = +2 Query: 14 PLDLVKCNMQVD-------PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 P D+VK Q KY + + +E+G+ G +KG + + + + Sbjct: 133 PTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCAE 192 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGF 349 Y+ K+ D + V A A V+A P++ VK R + + PG Sbjct: 193 MVTYDVIKEKVLDYHLLTDNLPCHFVSAFGAGFCATVVAS----PVDVVKTRYMNSPPGQ 248 Query: 350 ARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 + D + K+V EG YKG P + R + ++ F +E + + K Sbjct: 249 YQNPLDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVSYEQLKRALMK 299 Score = 37.7 bits (86), Expect = 0.020 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ-------PGFARCLTDGLPKLVRSEGAF 403 T + L + +A ADL P++ KVR+Q Q R + + +VR+EG Sbjct: 13 TAVKLLGAGTAACFADLLTFPLDTAKVRLQIQGENQAARSAQYRGVLGTILTMVRNEGPR 72 Query: 404 GLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 Y G+V RQ+ + ++ ++++ ++ PK D S Sbjct: 73 SPYNGLVAGLQRQMSFASIRIGLYDSVKQLY----TPKGSDHSS 112
>GHC2_RAT (Q505J6) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 42.7 bits (99), Expect = 6e-04 Identities = 39/190 (20%), Positives = 75/190 (39%), Gaps = 28/190 (14%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSK--YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 V P+DL K +Q K Y+ ++ + +G G ++G L + + A K Sbjct: 26 VFPIDLAKTRLQNQQGKDVYKGMTDCLVKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAA 85 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 ++ ++ N + + A A + + CPME +K+++Q A C Sbjct: 86 NDFLRQLLMQDGTQRNLK-----MEMLAGCGAGICQVVITCPMEMLKIQLQDAGRLAVCQ 140 Query: 362 -------------------TDGLP-------KLVRSEGAFGLYKGIVPLWGRQIPYTMMK 463 T P +L+R++G GLY+G+ R IP++++ Sbjct: 141 QASASATPTSRPYSTGSTSTHRRPSATLIAWELLRTQGLSGLYRGLGATLLRDIPFSIIY 200 Query: 464 FACFETIVEM 493 F F + ++ Sbjct: 201 FPLFANLNQL 210 Score = 38.1 bits (87), Expect = 0.016 Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 13/129 (10%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKC-YSDIAGPENADRLKTVIYLAA 265 LL+ QGL G ++G ATL+ F + + S++ G + T ++A Sbjct: 173 LLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTGKASF----THSFVAG 228 Query: 266 SASAEVIADLALCPMEAVKVRIQT-QPGFA----RCLTDGLPKLVRSEGAFGLYKG---- 418 A+ V A +A+ P++ +K RIQT + G R +TD KL EGA KG Sbjct: 229 CAAGSVSA-VAVTPLDVLKTRIQTLKKGLGEDTYRGVTDCARKLWTQEGAAAFMKGAGCR 287 Query: 419 ---IVPLWG 436 I PL+G Sbjct: 288 ALVIAPLFG 296 Score = 33.1 bits (74), Expect = 0.50 Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Frame = +2 Query: 275 AEVIADLALCPMEAVKVRIQTQPG--FARCLTDGLPKLVRSEGAFGLYKG 418 A ++ + P++ K R+Q Q G + +TD L K R+EG G+Y+G Sbjct: 18 AGLVGVTCVFPIDLAKTRLQNQQGKDVYKGMTDCLVKTARAEGFLGMYRG 67
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1| Length = 310 Score = 42.4 bits (98), Expect = 8e-04 Identities = 36/156 (23%), Positives = 64/156 (41%), Gaps = 16/156 (10%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSK---------------YRDISSGFGVLLQEQGLGGFFKGWMA 136 L + PLD+VK MQ+ + Y + +++++G +KG + Sbjct: 27 LVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKEGFSHLYKGITS 86 Query: 137 TLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRL-KTVIYLAASASAEVIADLALCPME 313 ++ + + A KF + F+ Y I N + K IY ASA A + + P E Sbjct: 87 PILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIYSGASAGA--VEAFVVAPFE 144 Query: 314 AVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGI 421 VK+R+Q + + + V G L+ G+ Sbjct: 145 LVKIRLQDVNSQFKTPIEVVKNSVVKGGVLSLFNGL 180 Score = 36.2 bits (82), Expect = 0.059 Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 19/119 (15%) Frame = +2 Query: 239 LKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-------------------PGFARCL 361 L + A A A V L + P++ VK R+Q Q G CL Sbjct: 9 LPFIYQFTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCL 68 Query: 362 TDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCSK 538 T K+V+ EG LYKGI + P +KF+ +T + YK P P + ++ Sbjct: 69 T----KIVKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTF-QTFYKKIFPTPNGEMTQ 122
>CG69_MOUSE (Q9D8K8) Mitochondrial carrier protein CGI-69 homolog| Length = 359 Score = 42.4 bits (98), Expect = 8e-04 Identities = 38/167 (22%), Positives = 68/167 (40%), Gaps = 10/167 (5%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 V PL+LV+ +Q YR+++S + + G + GW T + A + YE Sbjct: 179 VSPLELVRTKLQAQHVSYRELASSVQAAVTQGGWRSLWLGWGPTALRDVPFSALYWFNYE 238 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTD 367 K S ++G D+ I A + ++A P + VK + Q G + Sbjct: 239 LVK---SWLSGLRPKDQTSVGISFVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAVRV 295 Query: 368 GLPKL---------VRSE-GAFGLYKGIVPLWGRQIPYTMMKFACFE 478 P++ +R+E G GL+ G +P + P + + +E Sbjct: 296 KPPRVDSTWLLLRRIRAESGTRGLFAGFLPRIIKAAPSCAIMISTYE 342 Score = 38.9 bits (89), Expect = 0.009 Identities = 39/169 (23%), Positives = 68/169 (40%), Gaps = 6/169 (3%) Frame = +2 Query: 47 DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFK------KCYS 208 DP+++ F +++ +G + G ATLV A F Y+ K S Sbjct: 100 DPTRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQSLTS 159 Query: 209 DIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVR 388 D+ P + A A A + + P+E V+ ++Q Q R L + V Sbjct: 160 DLYAP-----------MVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELASSVQAAVT 208 Query: 389 SEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 G L+ G P R +P++ + + +E + + + +PKDQ S Sbjct: 209 QGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWL---SGLRPKDQTS 254
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 42.0 bits (97), Expect = 0.001 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 23/197 (11%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 AV P++ VK +QV + +Y+ I + +EQG F++G +A ++ Y Sbjct: 24 AVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 83 Query: 161 GACKFGFYEYFKKCYSDIAGPENADRLKTV-IYLAAS-ASAEVIADLALC---PMEAVKV 325 A F F + +K+ + DR K Y A + AS +LC P++ + Sbjct: 84 QALNFAFKDKYKQIFLG-----GVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFART 138 Query: 326 RIQTQ----------PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACF 475 R+ G C+T K+ +S+G GLY+G I Y F + Sbjct: 139 RLAADVGKGAAQREFTGLGNCIT----KIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVY 194 Query: 476 ETIVEMVYKHAVPKPKD 526 +T K +P PK+ Sbjct: 195 DTA-----KGMLPDPKN 206
>UCP3_BOVIN (O77792) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 41.2 bits (95), Expect = 0.002 Identities = 39/174 (22%), Positives = 68/174 (39%), Gaps = 11/174 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 P D+VK Q KY + + +E+G+ G +KG + + + + Sbjct: 136 PTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCGE 195 Query: 173 FGFYEYFKKCYSDIAGPENADRLKT---VIYLAASASAEVIADLALCPMEAVKVR-IQTQ 340 Y+ K+ D L T + ++ A A L P++ VK R + + Sbjct: 196 MVTYDIIKEKLLDY-------HLLTDNFPCHFVSAFGAGFCATLVASPVDVVKTRYMNSP 248 Query: 341 PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 PG D + K+V EG YKG P + R + ++ F +E + + K Sbjct: 249 PGQYHSPFDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQMKRALMK 302 Score = 37.7 bits (86), Expect = 0.020 Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 10/107 (9%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ----------PGFARCLTDGLPKLVRSE 394 T + A+ +A ADL P++ KVR+Q Q R + + +VR+E Sbjct: 13 TSVKFLAAGTAACFADLLTFPLDTAKVRLQIQGENQAALAARSAQYRGVLGTILTMVRTE 72 Query: 395 GAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 G LY G+V RQ+ + ++ ++++ + PK D S Sbjct: 73 GPRSLYSGLVAGLQRQMSFASIRIGLYDSVKQFY----TPKGSDHSS 115
>UCP2_RAT (P56500) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 40.8 bits (94), Expect = 0.002 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 11/97 (11%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ---PGFARCLTDG--------LPKLVRS 391 TV +L A +A IADL P++ KVR+Q Q G AR + +VR+ Sbjct: 14 TVKFLGAGTAA-CIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVRT 72 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 EG LY G+V RQ+ + ++ ++++ + K Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTK 109 Score = 31.6 bits (70), Expect = 1.5 Identities = 31/163 (19%), Positives = 61/163 (37%), Gaps = 6/163 (3%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 P D+VK Q +Y+ + + +E+G+ G +KG + + + Sbjct: 136 PTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCTELV 195 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGFAR 355 Y+ K D N + ++ A + P++ VK R + + G Sbjct: 196 TYDLIK----DTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYH 251 Query: 356 CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 ++R EG YKG +P + R + ++ F +E + Sbjct: 252 SAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQL 294
>ADT3_YEAST (P18238) ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine| nucleotide translocator 3) (ANT 3) Length = 307 Score = 40.8 bits (94), Expect = 0.002 Identities = 38/155 (24%), Positives = 69/155 (44%), Gaps = 8/155 (5%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 KY I F +++GL F++G A ++ Y A F F + K + E Sbjct: 55 KYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFG--FKKEEGY 112 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRI-----QTQPGFARC---LTDGLPKLVRS 391 LA+ +A ++ L + ++ + R+ ++ G AR LTD K ++S Sbjct: 113 GKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKS 172 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 +G GLY+G +P + Y + F F+++ +V Sbjct: 173 DGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLV 207 Score = 34.7 bits (78), Expect = 0.17 Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 14/153 (9%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPS--------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSS 157 L V LD + + D ++ ++ + L+ G+ G ++G+M ++VG Sbjct: 132 LFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVV 191 Query: 158 QGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVI---ADLALCPMEAVKVR 328 FG ++ K + G + +LA+ V+ A P++ V+ R Sbjct: 192 YRGLYFGMFDSLKPLV--LTGSLDGS------FLASFLLGWVVTTGASTCSYPLDTVRRR 243 Query: 329 IQTQPGFA---RCLTDGLPKLVRSEGAFGLYKG 418 + G A D L K+V SEG L+KG Sbjct: 244 MMMTSGQAVKYNGAIDCLKKIVASEGVGSLFKG 276
>FLX1_YEAST (P40464) Mitochondrial FAD carrier protein FLX1| Length = 311 Score = 40.8 bits (94), Expect = 0.002 Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 3/145 (2%) Frame = +2 Query: 59 YRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD- 235 Y + +G LL+ G G +KG + L G S QGA F Y+ K+ D Sbjct: 164 YTSMYNGVQQLLRTDGFQGLWKGLVPALFGVS-QGALYFAVYDTLKQRKLRRKRENGLDI 222 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC--LTDGLPKLVRSEGAFGL 409 L + + ++ ++++ + P + +K +Q+ + L + ++ ++G GL Sbjct: 223 HLTNLETIEITSLGKMVSVTLVYPFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGL 282 Query: 410 YKGIVPLWGRQIPYTMMKFACFETI 484 YKG+ R IP T + F +E + Sbjct: 283 YKGLSANLVRAIPSTCITFCVYENL 307
>MRS4_YEAST (P23500) Mitochondrial RNA-splicing protein MRS4| Length = 304 Score = 40.4 bits (93), Expect = 0.003 Identities = 32/159 (20%), Positives = 65/159 (40%), Gaps = 3/159 (1%) Frame = +2 Query: 14 PLDLVKCNMQ---VDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFY 184 P+D +K +Q ++ + + S + +G +KG + ++G A FG Y Sbjct: 43 PIDALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQSVILGAGPAHAVYFGTY 102 Query: 185 EYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT 364 E+ C + + PE+ + + + A + AD + P + VK R+Q + Sbjct: 103 EF---CKARLISPEDMQTHQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLR--VW 157 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFET 481 + ++ ++EG Y IP+ F +E+ Sbjct: 158 NVTKQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYES 196
>RIM2_YEAST (P38127) Mitochondrial carrier protein RIM2| Length = 377 Score = 40.4 bits (93), Expect = 0.003 Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 6/119 (5%) Frame = +2 Query: 83 GVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLA 262 G + +++G FKG LVG + F Y K Y A N + +I+L Sbjct: 124 GNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMY---AKAFNNGQETPMIHLM 180 Query: 263 ASASAEVIADLALCPMEAVKVRIQTQPGFARCLT------DGLPKLVRSEGAFGLYKGI 421 A+A+A A P+ +K R+Q + D L ++R+EG GLYKG+ Sbjct: 181 AAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGL 239
>GHC1_HUMAN (Q9H936) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 40.4 bits (93), Expect = 0.003 Identities = 41/194 (21%), Positives = 76/194 (39%), Gaps = 32/194 (16%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDISSGFGVLLQ---EQGLGGFFKGWMATLVGYSSQGACKFG 178 V P+DL K +Q + R +S L++ +G G ++G L + + A K Sbjct: 26 VFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLA 85 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ------ 340 ++F+ S ++ +L + + A A + PME +K+++Q Sbjct: 86 ANDFFRHQLS-----KDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQ 140 Query: 341 ----------------------PGFARCLTDGLPK-LVRSEGAFGLYKGIVPLWGRQIPY 451 P R L + L+RS G GLYKG+ R +P+ Sbjct: 141 RKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPF 200 Query: 452 TMMKFACFETIVEM 493 +++ F F + ++ Sbjct: 201 SVVYFPLFANLNQL 214 Score = 35.8 bits (81), Expect = 0.078 Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Frame = +2 Query: 275 AEVIADLALCPMEAVKVRIQTQPGFARCLT---DGLPKLVRSEGAFGLYKG 418 A +I + P++ K R+Q Q R T D L K VRSEG FG+Y+G Sbjct: 18 AGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRG 68 Score = 33.9 bits (76), Expect = 0.29 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 12/128 (9%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS 268 LL+ +G+ G +KG ATL+ F + + + P + ++ + A Sbjct: 177 LLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANL----NQLGRPASEEKSPFYVSFLAG 232 Query: 269 ASAEVIADLALCPMEAVKVRIQT-QPGFARCLTDGL----PKLVRSEGAFGLYKG----- 418 A A +A+ P + VK R+Q+ Q G G+ K++R EG KG Sbjct: 233 CVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRA 292 Query: 419 --IVPLWG 436 I PL+G Sbjct: 293 LVIAPLFG 300
>YDE9_SCHPO (Q10442) Putative mitochondrial carrier C12B10.09| Length = 345 Score = 40.0 bits (92), Expect = 0.004 Identities = 38/160 (23%), Positives = 71/160 (44%), Gaps = 1/160 (0%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 L++ P+D +K +Q G ++ G G ++G + LVG + + F Sbjct: 98 LSLFPIDTLKTRLQAK-----------GGFVKNGGFHGVYRGLGSILVGSAPGASLFFTT 146 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 YE K S +G +D I++ +++ E+ A + P E +K R Q G Sbjct: 147 YENMKSRLSQ-SGLGLSD---PQIHMCSASLGEIAACIVRVPTEVIKQRAQASGGTLSS- 201 Query: 362 TDGLPKLVRSEGAF-GLYKGIVPLWGRQIPYTMMKFACFE 478 + L +++S + Y G R+IP+T+++F +E Sbjct: 202 RNILQTILKSNNVWRDFYAGYGITIAREIPFTLIQFPIWE 241 Score = 33.9 bits (76), Expect = 0.29 Identities = 20/76 (26%), Positives = 36/76 (47%) Frame = +2 Query: 257 LAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWG 436 L A A + DL+L P++ +K R+Q + GF V++ G G+Y+G+ + Sbjct: 86 LGAGICAGLAVDLSLFPIDTLKTRLQAKGGF-----------VKNGGFHGVYRGLGSILV 134 Query: 437 RQIPYTMMKFACFETI 484 P + F +E + Sbjct: 135 GSAPGASLFFTTYENM 150 Score = 30.4 bits (67), Expect = 3.3 Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 3/53 (5%) Frame = +2 Query: 284 IADLALCPMEAVKVRIQT-QPGFARCLTDGLPKLVRSEGAFGLYKGIVP--LW 433 IA P + VK RI T Q + T + +V EG LYKGIVP LW Sbjct: 271 IAAALTTPFDVVKTRIMTSQQRLSYVFT--IKSIVAHEGFLALYKGIVPRVLW 321
>ADT1_ARATH (P31167) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 381 Score = 40.0 bits (92), Expect = 0.004 Identities = 34/164 (20%), Positives = 71/164 (43%), Gaps = 9/164 (5%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I FG ++++G G ++G A ++ Y A F F +YFK+ Sbjct: 113 EMIKAGRLSEP--YKGIGDCFGRTIKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKR 170 Query: 200 CYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR-------- 355 + + + LA+ +A + L + ++ + R+ A+ Sbjct: 171 LF-NFKKDRDGYWKWFAGNLASGGAAGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQF 229 Query: 356 -CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 L D K ++++G GLY+G I Y + F ++++ Sbjct: 230 DGLVDVYRKTLKTDGIAGLYRGFNISCVGIIVYRGLYFGLYDSV 273 Score = 32.7 bits (73), Expect = 0.66 Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 6/115 (5%) Frame = +2 Query: 92 LQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASA 271 L+ G+ G ++G+ + VG FG Y+ K + G + A+ A Sbjct: 240 LKTDGIAGLYRGFNISCVGIIVYRGLYFGLYDSVKPVL--LTGDLQDS------FFASFA 291 Query: 272 SAEVI---ADLALCPMEAVKVRIQTQPGFA---RCLTDGLPKLVRSEGAFGLYKG 418 VI A LA P++ V+ R+ G A + D +++++EGA L+KG Sbjct: 292 LGWVITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFKQILKNEGAKSLFKG 346
>ADT1_SOLTU (P25083) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 386 Score = 39.7 bits (91), Expect = 0.005 Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 8/141 (5%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I FG ++E+G G ++G A ++ Y A F F +YFK+ Sbjct: 119 EMLKAGRLSEP--YKGIGECFGRTIKEEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKR 176 Query: 200 CYSDIAGPEN-----ADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR--- 355 ++ + A L + A ++S + L R ++ G R Sbjct: 177 LFNFKKDRDGYWKWFAGNLASG-GAAGASSLFFVYSLDYARTRLANDRKASKKGGERQFN 235 Query: 356 CLTDGLPKLVRSEGAFGLYKG 418 L D K ++S+G GLY+G Sbjct: 236 GLVDVYKKTLKSDGIAGLYRG 256
>PET8_ASHGO (O60029) Putative mitochondrial carrier protein PET8| Length = 271 Score = 39.3 bits (90), Expect = 0.007 Identities = 36/161 (22%), Positives = 67/161 (41%), Gaps = 6/161 (3%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P+D +K +Q G G G ++G + +V + + F Y+ Sbjct: 25 PIDTLKTRLQAK-----------GGFFHNGGYRGIYRGLGSAVVASAPGASLFFVTYDSM 73 Query: 194 KKCYSDIAGPENADR--LKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTD 367 K+ + G A + + ++ +S+ E+ A L P E +K R QT + T Sbjct: 74 KQQLRPVMGRWTASEQLAEVLTHMLSSSLGEMSACLVRVPAEVIKQRTQTHHTNSSLQT- 132 Query: 368 GLPKLVRSEGAFGLYKGIVPLWG----RQIPYTMMKFACFE 478 L ++R G+ +G+ W R+IP+T ++F +E Sbjct: 133 -LRLILRDPTGEGVVRGLYRGWWTTIMREIPFTCIQFPLYE 172 Score = 35.0 bits (79), Expect = 0.13 Identities = 28/105 (26%), Positives = 44/105 (41%) Frame = +2 Query: 113 GFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIAD 292 G ++GW T++ +F YEY KK ++ A E + + + A IA Sbjct: 148 GLYRGWWTTIMREIPFTCIQFPLYEYLKKKWAAYAEIERVSAWQGAV---CGSLAGGIAA 204 Query: 293 LALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVP 427 A P++ +K R+ L L R EGA ++GI P Sbjct: 205 AATTPLDVLKTRMMLHERRVPML-HLARTLFREEGARVFFRGIGP 248
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier| Length = 327 Score = 39.3 bits (90), Expect = 0.007 Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 3/173 (1%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGF 181 L P + VK +Q SK I + +++E G+ FKG +ATL A F Sbjct: 157 LVTAPTERVKVVLQTS-SKGSFIQAA-KTIVKEGGIASLFKGSLATLARDGPGSALYFAS 214 Query: 182 YEYFKKCYSDIAGPENADRLKTVIYL---AASASAEVIADLALCPMEAVKVRIQTQPGFA 352 YE K + ++A + + V L A A + LA+ P++ +K ++Q Sbjct: 215 YEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKLQASSTRQ 274 Query: 353 RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAV 511 L+ ++ G G + G+ P R P F E + K+ + Sbjct: 275 NMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVEMTHSLFKKYGI 327
>UCP2_MOUSE (P70406) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 39.3 bits (90), Expect = 0.007 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ---PGFARCLTDG--------LPKLVRS 391 TV +L A +A IADL P++ KVR+Q Q G R + +VR+ Sbjct: 14 TVKFLGAGTAA-CIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRT 72 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 EG LY G+V RQ+ + ++ ++++ + K Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTK 109 Score = 32.0 bits (71), Expect = 1.1 Identities = 31/163 (19%), Positives = 61/163 (37%), Gaps = 6/163 (3%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 P D+VK Q +Y+ + + +E+G+ G +KG + + + Sbjct: 136 PTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELV 195 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGFAR 355 Y+ K D N + ++ A + P++ VK R + + G Sbjct: 196 TYDLIK----DTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYH 251 Query: 356 CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 ++R EG YKG +P + R + ++ F +E + Sbjct: 252 SAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQL 294
>ADT1_WHEAT (Q41629) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 331 Score = 38.9 bits (89), Expect = 0.009 Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 14/147 (9%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I FG ++++G G ++G A ++ Y A F F +YFK+ Sbjct: 64 EMIKAGRLSEP--YKGIGDCFGRTIKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKR 121 Query: 200 CYSDIAGPENADRLKTVIY------LAASASAEVIADLALCPMEAVKVRIQTQPGFAR-- 355 + N + K + LA+ +A + + ++ + R+ ++ Sbjct: 122 MF-------NFKKDKDGYWKWFGGNLASGGAAGASSLFFVYSLDYARTRLANDAKASKGG 174 Query: 356 ------CLTDGLPKLVRSEGAFGLYKG 418 L D K ++S+G GLY+G Sbjct: 175 GERQFNGLVDVYRKTLKSDGIAGLYRG 201 Score = 35.4 bits (80), Expect = 0.10 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 6/115 (5%) Frame = +2 Query: 92 LQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASA 271 L+ G+ G ++G+ + VG FG Y+ K P V + A+ A Sbjct: 190 LKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSLK--------PVLLTGTLQVCFFASFA 241 Query: 272 SAEVI---ADLALCPMEAVKVRIQTQPGFA---RCLTDGLPKLVRSEGAFGLYKG 418 +I A LA P++ V+ R+ G A + D ++++ EGA L+KG Sbjct: 242 LGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGAKSLFKG 296
>YAD8_SCHPO (Q09834) Putative mitochondrial carrier C4G8.08| Length = 271 Score = 38.9 bits (89), Expect = 0.009 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +2 Query: 248 VIYLAASASAEVIADLALCPMEAVKVRIQ-TQPGFARCLTDGLPKLVRSEGAFGLYKGIV 424 ++Y +AEV++ P+E +K R Q +Q G + + + L RSEG G Y+G Sbjct: 84 ILYSICGMTAEVVSSFVWTPLEVIKARTQISQKG---SVINTISTLARSEGLKGFYRGYW 140 Query: 425 PLWGRQIPYTMMKFACFETIVEMVYKHA 508 +P T+ + C+E + + K + Sbjct: 141 MGVAIYLPTTVSWWVCYEESKKYLQKQS 168 Score = 33.9 bits (76), Expect = 0.29 Identities = 29/107 (27%), Positives = 48/107 (44%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 PL+++K Q+ S+ + + L + +GL GF++G+ + Y + YE Sbjct: 103 PLEVIKARTQI--SQKGSVINTISTLARSEGLKGFYRGYWMGVAIYLPTTVSWWVCYEES 160 Query: 194 KKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ 334 KK + N D +VI SA V+A P++ VK R Q Sbjct: 161 KKY---LQKQSNWD--ISVIAPICSALGTVVATTISTPLDIVKTRYQ 202
>ADT2_WHEAT (Q41630) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 331 Score = 38.5 bits (88), Expect = 0.012 Identities = 17/63 (26%), Positives = 34/63 (53%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I FG ++++G G ++G A ++ Y A F F +YFK+ Sbjct: 64 EMIKAGRLSEP--YKGIGDCFGRTIKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKR 121 Query: 200 CYS 208 ++ Sbjct: 122 MFN 124
>GHC1_PONPY (Q5RD81) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 38.5 bits (88), Expect = 0.012 Identities = 41/194 (21%), Positives = 73/194 (37%), Gaps = 32/194 (16%) Frame = +2 Query: 8 VXPLDLVKC---NMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 V P+DL K N Q Y +S ++ +G G ++G L + + A K Sbjct: 26 VFPIDLAKTRLQNQQNGQRMYTSMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLA 85 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ------ 340 ++F+ S ++ +L + + A A + PME +K+++Q Sbjct: 86 ANDFFRHQLS-----KDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQ 140 Query: 341 ----------------------PGFARCLTDGLPK-LVRSEGAFGLYKGIVPLWGRQIPY 451 P R L + L+RS G GLYKG+ R +P Sbjct: 141 RKILAAQGQLSAQGGAQPSVEAPAAPRPTAIQLTRDLLRSRGIAGLYKGLGATLLRDVPL 200 Query: 452 TMMKFACFETIVEM 493 +++ F F + ++ Sbjct: 201 SVVYFPLFANLNQL 214 Score = 35.4 bits (80), Expect = 0.10 Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Frame = +2 Query: 275 AEVIADLALCPMEAVKVRIQTQPGFARCLT---DGLPKLVRSEGAFGLYKG 418 A +I + P++ K R+Q Q R T D L K +RSEG FG+Y+G Sbjct: 18 AGLIGVTCVFPIDLAKTRLQNQQNGQRMYTSMSDCLIKTIRSEGYFGMYRG 68 Score = 34.3 bits (77), Expect = 0.23 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 12/128 (9%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS 268 LL+ +G+ G +KG ATL+ F + + + P + ++ + A Sbjct: 177 LLRSRGIAGLYKGLGATLLRDVPLSVVYFPLFANL----NQLGRPASEEKSPFYVSFLAG 232 Query: 269 ASAEVIADLALCPMEAVKVRIQT-QPGFARCLTDGL----PKLVRSEGAFGLYKG----- 418 A A +A+ P + VK R+Q+ Q G G+ K++R EG KG Sbjct: 233 CVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRA 292 Query: 419 --IVPLWG 436 I PL+G Sbjct: 293 LVIAPLFG 300
>ADT_ORYSA (P31691) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 382 Score = 38.5 bits (88), Expect = 0.012 Identities = 36/173 (20%), Positives = 73/173 (42%), Gaps = 14/173 (8%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I FG ++++G ++G A ++ Y A F F +YFK+ Sbjct: 115 EMIKAGRLSEP--YKGIGDCFGRTIKDEGFASLWRGNTANVIRYFPTQALNFAFKDYFKR 172 Query: 200 CYSDIAGPENADRLKTVIY------LAASASAEVIADLALCPMEAVKVRIQTQPGFAR-- 355 + N + K + LA+ +A + + ++ + R+ A+ Sbjct: 173 LF-------NFKKDKDGYWKWFGGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGG 225 Query: 356 ------CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 L D K ++S+G GLY+G I Y + F ++++ +V Sbjct: 226 GERQFNGLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVV 278 Score = 34.7 bits (78), Expect = 0.17 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 6/115 (5%) Frame = +2 Query: 92 LQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASA 271 L+ G+ G ++G+ + VG FG Y+ K + +N + A+ A Sbjct: 241 LKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVVLTGSLQDN--------FFASFA 292 Query: 272 SAEVI---ADLALCPMEAVKVRIQTQPGFA---RCLTDGLPKLVRSEGAFGLYKG 418 +I A LA P++ V+ R+ G A + D +++++EGA L+KG Sbjct: 293 LGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSMDAFSQILKNEGAKSLFKG 347
>GHC1_MOUSE (Q9D6M3) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 38.1 bits (87), Expect = 0.016 Identities = 40/194 (20%), Positives = 72/194 (37%), Gaps = 32/194 (16%) Frame = +2 Query: 8 VXPLDLVKC---NMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 V P+DL K N Q Y +S ++ +G G ++G L + + A K Sbjct: 26 VFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLA 85 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQ-------- 334 ++F+ S ++ +L + A A + PME +K+++Q Sbjct: 86 ANDFFRHQLS-----KDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQ 140 Query: 335 ---------------TQPGFAR------CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPY 451 QP T L+R+ G GLYKG+ R +P+ Sbjct: 141 RKILAAQAQLSAQGGAQPSVEAPAPPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPF 200 Query: 452 TMMKFACFETIVEM 493 +++ F F + ++ Sbjct: 201 SIVYFPLFANLNQL 214 Score = 35.0 bits (79), Expect = 0.13 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Frame = +2 Query: 275 AEVIADLALCPMEAVKVRIQTQPGFARC---LTDGLPKLVRSEGAFGLYKG 418 A +I + P++ K R+Q Q R ++D L K +RSEG FG+Y+G Sbjct: 18 AGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRG 68 Score = 33.5 bits (75), Expect = 0.38 Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 16/132 (12%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAAS 268 LL+ G+ G +KG ATL+ F + + + P + ++ + A Sbjct: 177 LLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANL----NQLGRPSSEEKSPFYVSFLAG 232 Query: 269 ASAEVIADLALCPMEAVKVRIQ---------TQPGFARCLTDGLPKLVRSEGAFGLYKG- 418 A A +A+ P + VK R+Q T GF C K+ R EG KG Sbjct: 233 CVAGSAAAVAVNPCDVVKTRLQSLERGVNEDTYSGFLDCAR----KIWRHEGPSAFLKGA 288 Query: 419 ------IVPLWG 436 I PL+G Sbjct: 289 YCRALVIAPLFG 300
>UCP2_HUMAN (P55851) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 38.1 bits (87), Expect = 0.016 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ---PGFARCLTDG--------LPKLVRS 391 TV +L A +A IADL P++ KVR+Q Q G R + +VR+ Sbjct: 14 TVKFLGAGTAA-CIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRT 72 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 EG LY G+V RQ+ + ++ ++++ + K Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTK 109 Score = 28.9 bits (63), Expect = 9.5 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 1/63 (1%) Frame = +2 Query: 14 PLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 P+D+VK M +Y +LQ++G F+KG+M + + S F YE Sbjct: 234 PVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQ 293 Query: 191 FKK 199 K+ Sbjct: 294 LKR 296
>UCP2_CANFA (Q9N2J1) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 38.1 bits (87), Expect = 0.016 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ---PGFARCLTDG--------LPKLVRS 391 TV +L A +A IADL P++ KVR+Q Q G R + +VR+ Sbjct: 14 TVKFLGAGTAA-CIADLITFPLDTAKVRLQIQGERQGPVRAAASAQYRGVLCTILTMVRT 72 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 EG LY G+V RQ+ + ++ ++++ + K Sbjct: 73 EGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTK 109 Score = 28.9 bits (63), Expect = 9.5 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 1/63 (1%) Frame = +2 Query: 14 PLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 P+D+VK M +Y +LQ++G F+KG+M + + S F YE Sbjct: 234 PVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQ 293 Query: 191 FKK 199 K+ Sbjct: 294 LKR 296
>UCP1_CANFA (Q9GMZ1) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 309 Score = 38.1 bits (87), Expect = 0.016 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 10/90 (11%) Frame = +2 Query: 251 IYLAASASAEVIADLALCPMEAVKVRIQTQ----------PGFARCLTDGLPKLVRSEGA 400 + +AA+A A +AD+ P++ KVR+Q Q P + R + + L R+EG Sbjct: 15 VRIAAAAGAACLADMITFPLDTAKVRLQIQGEGQGQPPRAPRY-RGVLGTVATLARTEGL 73 Query: 401 FGLYKGIVPLWGRQIPYTMMKFACFETIVE 490 LY G+ RQ+ + ++ ++++ E Sbjct: 74 QKLYSGLPAGLQRQVGFASLRIGLYDSVRE 103 Score = 35.4 bits (80), Expect = 0.10 Identities = 34/170 (20%), Positives = 68/170 (40%), Gaps = 7/170 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPS------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 P ++VK +Q +Y + + ++ +GL G +KG L+ + Sbjct: 135 PTEVVKVRLQAQSHLHGRKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRNVIINCTEL 194 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGFA 352 Y+ K+ + AD L + ++ A + P++ VK R + + P Sbjct: 195 VTYDLMKEAL--VKNHLLADDLPC--HFLSALVAGFCTTVLSSPVDVVKTRFVNSVPEQY 250 Query: 353 RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 + + ++ EG +KG VP + R + ++ F CFE + + K Sbjct: 251 TSVPNCAMTMLTKEGPLAFFKGFVPSFLRLGSWNVIMFVCFEQLKRELMK 300 Score = 35.4 bits (80), Expect = 0.10 Identities = 38/180 (21%), Positives = 67/180 (37%), Gaps = 16/180 (8%) Frame = +2 Query: 14 PLDLVKCNMQVDPS---------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGA 166 PLD K +Q+ +YR + L + +GL + G A L + Sbjct: 33 PLDTAKVRLQIQGEGQGQPPRAPRYRGVLGTVATLARTEGLQKLYSGLPAGLQRQVGFAS 92 Query: 167 CKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ-- 340 + G Y+ ++ S G + + + +A I P E VKVR+Q Q Sbjct: 93 LRIGLYDSVREWLSPGQGAAASLGSRISAGVMTGGAAVFIGQ----PTEVVKVRLQAQSH 148 Query: 341 -----PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKH 505 P + + + +EG GL+KG P R + + ++ + E + K+ Sbjct: 149 LHGRKPRYTGTY-NAYRIIATTEGLTGLWKGTTPNLMRNVIINCTELVTYDLMKEALVKN 207
>ADT1_GOSHI (O22342) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 386 Score = 37.7 bits (86), Expect = 0.020 Identities = 31/141 (21%), Positives = 62/141 (43%), Gaps = 8/141 (5%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I F ++++G G ++G A ++ Y A F F +YFK+ Sbjct: 119 EMIKSGRLSEP--YKGIGDCFKRTIKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKR 176 Query: 200 CYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR-------- 355 + + + LA+ +A + L + ++ + R+ A+ Sbjct: 177 LF-NFKKDRDGYWKWFAGNLASGGAAGASSLLFVYSLDYARTRLANDAKAAKKGGERQFN 235 Query: 356 CLTDGLPKLVRSEGAFGLYKG 418 L D K ++S+G GLY+G Sbjct: 236 GLVDVYRKTLKSDGIAGLYRG 256
>UCP2_CYPCA (Q9W725) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 37.4 bits (85), Expect = 0.027 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 12/98 (12%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ------------PGFARCLTDGLPKLVR 388 TV ++ A +A IADL P++ KVR+Q Q P R + + +VR Sbjct: 14 TVKFIGAGTAA-CIADLFTFPLDTAKVRLQIQGESKIPVNTGHGPVKYRGVFGTISTMVR 72 Query: 389 SEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 EG LY G+V RQ+ + ++ ++++ + K Sbjct: 73 VEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTK 110 Score = 30.0 bits (66), Expect = 4.3 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Frame = +2 Query: 14 PLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 P+D+VK M P +Y + +L ++G F+KG+M + + S F YE Sbjct: 235 PVDVVKTRYMNSAPGQYCSALNCAVAMLTKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQ 294 Query: 191 FKK 199 K+ Sbjct: 295 LKR 297
>UCP2_BRARE (Q9W720) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 37.4 bits (85), Expect = 0.027 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 12/98 (12%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ------------PGFARCLTDGLPKLVR 388 TV ++ A +A IADL P++ KVR+Q Q P R + + +VR Sbjct: 14 TVKFIGAGTAA-CIADLFTFPLDTAKVRLQIQGENKASTNMGRGPVKYRGVFGTISTMVR 72 Query: 389 SEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 EG LY G+V RQ+ + ++ ++++ + K Sbjct: 73 VEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTK 110 Score = 28.9 bits (63), Expect = 9.5 Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Frame = +2 Query: 2 LAVXPLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 + P+D+VK M +Y + +L ++G FFKG+M + + S F Sbjct: 231 IIASPVDVVKTRYMNSAQGQYSSALNCAVAMLTKKGPKAFFKGFMPSFLRLGSWNVVMFV 290 Query: 179 FYEYFKK 199 YE K+ Sbjct: 291 TYEQLKR 297
>UCP2_PIG (O97562) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 37.0 bits (84), Expect = 0.035 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 11/91 (12%) Frame = +2 Query: 245 TVIYLAASASAEVIADLALCPMEAVKVRIQTQ-----------PGFARCLTDGLPKLVRS 391 TV +L A +A IADL P++ KVR+Q Q R + + +VR+ Sbjct: 14 TVKFLGAGTAA-CIADLITFPLDTAKVRLQIQGERRGPVQAAASAQYRGVLGTILTMVRN 72 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 EG LY G+V RQ+ + ++ ++++ Sbjct: 73 EGPRSLYNGLVAGLQRQMSFASVRIGLYDSV 103 Score = 34.7 bits (78), Expect = 0.17 Identities = 33/163 (20%), Positives = 62/163 (38%), Gaps = 6/163 (3%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-----KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 P D+VK Q +YR + + +E+GL G +KG + + + Sbjct: 136 PTDVVKVRFQAQARAGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPNVARNAIVNCAELV 195 Query: 179 FYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGFAR 355 Y+ K + D L + ++ A + P++ VK R + + PG Sbjct: 196 TYDLIKDTL--LKADLMTDDLP--CHFTSAFGAGFCTTVIASPVDVVKTRYMNSAPGQYS 251 Query: 356 CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 +++ EG YKG P + R + ++ F +E + Sbjct: 252 SAGHCALTMLQKEGPRAFYKGFTPSFLRLGSWNVVMFVTYEQL 294
>ADT_SCHPO (Q09188) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 322 Score = 36.6 bits (83), Expect = 0.045 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 9/156 (5%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 +Y+ I F E+G+ ++G A ++ Y A F F + FKK + E Sbjct: 70 RYKGIGECFKRTAAEEGVISLWRGNTANVLRYFPTQALNFAFKDKFKKMFG--YKKERDG 127 Query: 236 RLKTVI-YLAASASAEVIADLALCPMEAVKVRIQTQPGFARC--------LTDGLPKLVR 388 K LA+ +A + L + ++ + R+ A+ L D K R Sbjct: 128 YAKWFAGNLASGGAAGAASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYR 187 Query: 389 SEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 S+G GLY+G P + Y + F ++T+ +V Sbjct: 188 SDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVV 223
>ADT2_SOLTU (P27081) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) (Fragment) Length = 386 Score = 36.2 bits (82), Expect = 0.059 Identities = 30/142 (21%), Positives = 60/142 (42%), Gaps = 9/142 (6%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I F ++++G ++G A ++ Y A F F +YFK+ Sbjct: 118 EMIKAGRLSEP--YKGIGDCFSRTIKDEGFAALWRGNTANVIRYFPTQALNFAFKDYFKR 175 Query: 200 CYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR-------- 355 + + + LA+ A + L + ++ + R+ A+ Sbjct: 176 LF-NFKKDRDGYWKWFAGNLASGGGAGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQF 234 Query: 356 -CLTDGLPKLVRSEGAFGLYKG 418 L D K ++S+G GLY+G Sbjct: 235 DGLVDVYRKTLKSDGVAGLYRG 256
>PM47A_CANBO (P21245) Peroxisomal membrane protein PMP47A| Length = 423 Score = 36.2 bits (82), Expect = 0.059 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 14/127 (11%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIY---- 256 +L++QG G + G + L G + + FYE K + + P+ A K V Sbjct: 83 ILKDQGAKGLYNGLESALFGIAVTNFVYYYFYELTGKTLNRRSNPQTASNSKKVALKKGL 142 Query: 257 -----LAASASAEVIADLALCPMEAVKVRI----QTQPGFARCLT-DGLPKLVRSEGAFG 406 +AA A A I+ +A P+ R+ + Q + T + + ++++EG Sbjct: 143 SVWQSMAAGAVAGTISRVATNPIWVANTRMTILSKNQGKLGKLNTIEAIIYILKNEGWQK 202 Query: 407 LYKGIVP 427 L+ GIVP Sbjct: 203 LFTGIVP 209
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor| Length = 329 Score = 36.2 bits (82), Expect = 0.059 Identities = 25/121 (20%), Positives = 51/121 (42%), Gaps = 12/121 (9%) Frame = +2 Query: 14 PLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYF 193 P D K +Q ++ + L++ +G+ F+KG + L+G + +FG E Sbjct: 54 PFDTTKVRLQTATTRTTTLEV-LRNLVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAM 112 Query: 194 KKCYSDIAGPEN------------ADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQT 337 K+ + + +N ++ L Y + V+ P+E +++R+QT Sbjct: 113 KRFFQNYNASKNPNMSSQDVDLSRSNTLPLSQYYVCGLTGGVVNSFLASPIEQIRIRLQT 172 Query: 338 Q 340 Q Sbjct: 173 Q 173 Score = 31.6 bits (70), Expect = 1.5 Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Frame = +2 Query: 305 PMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKG-IVPLWG 436 P + KVR+QT L + L LV++EG F YKG + PL G Sbjct: 54 PFDTTKVRLQTATTRTTTL-EVLRNLVKNEGVFAFYKGALTPLLG 97 Score = 30.4 bits (67), Expect = 3.3 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVD----PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGAC 169 L V PLD+VK +Q D P IS + ++G+ FFKG+ T+V + Sbjct: 255 LTVYPLDVVKSIIQNDDLRKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGA 314 Query: 170 KFGFYE 187 F +E Sbjct: 315 TFLTFE 320
>UCP1_RABIT (P14271) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 35.8 bits (81), Expect = 0.078 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 9/89 (10%) Frame = +2 Query: 251 IYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGL---------PKLVRSEGAF 403 + + ++ A +AD+ P++ KVR Q Q F +T G+ L ++EG Sbjct: 15 VKIFSAGVAACLADVITFPLDTAKVRQQIQGEFP--ITSGIRYKGVLGTITTLAKTEGPL 72 Query: 404 GLYKGIVPLWGRQIPYTMMKFACFETIVE 490 LY G+ RQI + ++ ++T+ E Sbjct: 73 KLYSGLPAGLQRQISFASLRIGLYDTVQE 101 Score = 32.3 bits (72), Expect = 0.86 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Frame = +2 Query: 305 PMEAVKVR-IQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFET 481 P++ VK R I + PG + + + EG +KG VP + R + ++ F CFE Sbjct: 231 PVDVVKTRFINSPPGQYASVPNCAMTMFTKEGPTAFFKGFVPSFLRLGSWNVIMFVCFEK 290 Query: 482 I 484 + Sbjct: 291 L 291
>ADT2_MAIZE (P12857) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 387 Score = 35.8 bits (81), Expect = 0.078 Identities = 34/167 (20%), Positives = 71/167 (42%), Gaps = 8/167 (4%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I+ F ++++G ++G A ++ Y A F F +YFK+ Sbjct: 120 EMIKSGRLSEP--YKGIADCFKRTIKDEGFSSLWRGNTANVIRYFPTQALNFAFKDYFKR 177 Query: 200 CYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR-------- 355 + + + LA+ +A + + ++ + R+ A+ Sbjct: 178 LF-NFKKDRDGYWKWFAGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGGGDRQFN 236 Query: 356 CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 L D K ++S+G GLY+G I Y + F +++I +V Sbjct: 237 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVV 283
>PM34_HUMAN (O43808) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 35.4 bits (80), Expect = 0.10 Identities = 36/165 (21%), Positives = 69/165 (41%), Gaps = 10/165 (6%) Frame = +2 Query: 35 NMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDI 214 N + P+ Y+ I F +++++G+ + G +L+ + A +F FYE K+ Sbjct: 138 NEDIVPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNP-AIQFMFYEGLKRQLL-- 194 Query: 215 AGPENADRLKTVIYLAASASAEVIADLALCPMEAVKV-----RIQTQP-----GFARCLT 364 + +L ++ A A+ IA P++ V+ R + P G R + Sbjct: 195 ---KKRMKLSSLDVFIIGAVAKAIATTVTYPLQTVQSILRFGRHRLNPENRTLGSLRNIL 251 Query: 365 DGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVY 499 L + VR G GLYKG+ + + + F +E + + Sbjct: 252 YLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATF 296
>ADT2_YEAST (P18239) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 318 Score = 35.4 bits (80), Expect = 0.10 Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 8/151 (5%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 KY I F ++G+ F++G A ++ Y A F F + K + E Sbjct: 66 KYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFG--FKKEEGY 123 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRI-----QTQPGFARC---LTDGLPKLVRS 391 LA+ +A ++ L + ++ + R+ ++ G AR L D K ++S Sbjct: 124 AKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKS 183 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 +G GLY+G +P + Y + F ++++ Sbjct: 184 DGVAGLYRGFLPSVVGIVVYRGLYFGMYDSL 214 Score = 30.4 bits (67), Expect = 3.3 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 6/115 (5%) Frame = +2 Query: 92 LQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASA 271 L+ G+ G ++G++ ++VG FG Y+ K + G +LA+ Sbjct: 181 LKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLL--LTGSLEGS------FLASFL 232 Query: 272 SAEVI---ADLALCPMEAVKVRIQTQPGFARCLT---DGLPKLVRSEGAFGLYKG 418 V+ A P++ V+ R+ G A D L K+V +EG L+KG Sbjct: 233 LGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKG 287
>ARG13_NEUCR (Q01356) Amino acid transporter arg-13| Length = 363 Score = 35.4 bits (80), Expect = 0.10 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 5/103 (4%) Frame = +2 Query: 233 DRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDG----LPKLVRSEGA 400 + L+ ++Y ++A ++ P + VKVR+Q+QP G + +R++G Sbjct: 41 EALEDIVY---GSAAGIVGKYIEYPFDTVKVRLQSQPDHLPLRYTGPLDCFRQSIRADGF 97 Query: 401 FGLYKGI-VPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKD 526 GLY+GI PL G + + + F FE I + + P+D Sbjct: 98 LGLYRGISAPLVGAALENSSLFF--FERIGRSLLYSSGFAPRD 138 Score = 34.3 bits (77), Expect = 0.23 Identities = 50/201 (24%), Positives = 79/201 (39%), Gaps = 35/201 (17%) Frame = +2 Query: 2 LAVXPLDLVKCNMQVDPSKYRDISSGFGV-------------LLQEQGLGGFFKGWMATL 142 L + P++LVKC +QV D G G + + +GL GF+ G + TL Sbjct: 159 LILTPVELVKCKIQVP-----DEPGGAGARQRQLKPIPVIKEIFRHEGLRGFWHGQLGTL 213 Query: 143 VGYSSQGACKFGFYEYFKKCY---SDIAGPENADRLKTVI-----------YLAASASAE 280 + + A FG E K + ++ A + + V+ A ASA Sbjct: 214 IREAGGCAAWFGSKETTSKWFRGRNERALLKRGASQEEVVASRERPLPLWQQAIAGASAG 273 Query: 281 VIADLALCPMEAVKVRIQTQP------GFARCLTDGLPKLVRSEGAFGLYK--GIVPLWG 436 + + P + VK R+QT P + +PK E A L+K GI + Sbjct: 274 MSYNFLFFPADTVKSRMQTSPIGGGGDNGGKGAATMMPKKSFGEEARALWKQAGIKGFY- 332 Query: 437 RQIPYTMMKFACFETIVEMVY 499 R T+++ A + MVY Sbjct: 333 RGCGITVLRSAPSSAFIFMVY 353
>PM47B_CANBO (Q00319) Peroxisomal membrane protein PMP47B| Length = 419 Score = 35.0 bits (79), Expect = 0.13 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 14/127 (11%) Frame = +2 Query: 89 LLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIY---- 256 +L++QG G + G + L G + + FYE K S + P+ K V Sbjct: 83 ILKDQGAKGLYNGLESALFGIAVTNFVYYYFYELTGKTLSRRSNPQTTSGSKKVTLKKGL 142 Query: 257 -----LAASASAEVIADLALCPMEAVKVRI----QTQPGFARCLT-DGLPKLVRSEGAFG 406 +AA A A I+ +A P+ R+ + Q + T + + ++++EG Sbjct: 143 SVWQSMAAGAVAGTISRVATNPIWVANTRMTILSKNQGKLGKLNTIEAIIYILKNEGWQK 202 Query: 407 LYKGIVP 427 L+ GIVP Sbjct: 203 LFTGIVP 209
>MFRN1_BOVIN (Q3ZBJ8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 171 Score = 35.0 bits (79), Expect = 0.13 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 8/98 (8%) Frame = +2 Query: 215 AGPENADRLKTVI----YLAASASAEVIADLALCPMEAVKVRIQT----QPGFARCLTDG 370 AG E+ + L T ++ A A A ++ + P+++VK R+Q+ + Sbjct: 31 AGSEDYENLPTSASLSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLNPDPKAHYTSVYGA 90 Query: 371 LPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 L K++R+EG + +G+ + P M FAC+E + Sbjct: 91 LKKIIRTEGFWRPLRGLNVMMMGAGPAHAMYFACYENM 128
>ADT_CHLRE (P27080) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 308 Score = 35.0 bits (79), Expect = 0.13 Identities = 33/160 (20%), Positives = 67/160 (41%), Gaps = 12/160 (7%) Frame = +2 Query: 53 SKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENA 232 S Y+ I F ++E+G G ++G A ++ Y A F F + FK+ + N Sbjct: 50 SPYKGIGECFVRTVREEGFGSLWRGNTANVIRYFPTQALNFAFKDKFKRMFG-----FNK 104 Query: 233 DRLKTVIY---LAASASAEVIADLALCPMEAVKVRIQTQPGFAR---------CLTDGLP 376 D+ + +A+ +A ++ + ++ + R+ A+ L D Sbjct: 105 DKEYWKWFAGNMASGGAAGAVSLSFVYSLDYARTRLANDAKSAKKGGGDRQFNGLVDVYR 164 Query: 377 KLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 K + S+G GLY+G + Y + F ++++ +V Sbjct: 165 KTIASDGIAGLYRGFNISCVGIVVYRGLYFGMYDSLKPVV 204
>CG69_HUMAN (Q9BZJ4) Mitochondrial carrier protein CGI-69| Length = 359 Score = 34.7 bits (78), Expect = 0.17 Identities = 35/167 (20%), Positives = 66/167 (39%), Gaps = 10/167 (5%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYE 187 + PL+L++ +Q YR++ + + + G + GW T + A + YE Sbjct: 179 ISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYE 238 Query: 188 YFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL-- 361 K S + G D+ + A + +A + P + VK + Q G + Sbjct: 239 LVK---SWLNGLRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRV 295 Query: 362 -------TDGLPKLVRSE-GAFGLYKGIVPLWGRQIPYTMMKFACFE 478 T L + +R+E G GL+ G +P + P + + +E Sbjct: 296 NPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342 Score = 34.3 bits (77), Expect = 0.23 Identities = 38/169 (22%), Positives = 67/169 (39%), Gaps = 6/169 (3%) Frame = +2 Query: 47 DPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFK------KCYS 208 DP+++ F +++ +G + G ATLV A F Y+ K S Sbjct: 100 DPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTS 159 Query: 209 DIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVR 388 D+ P + A A A + + P+E ++ ++Q Q R L + V Sbjct: 160 DLYAP-----------MVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVA 208 Query: 389 SEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPKDQCS 535 G L+ G P R +P++ + + +E + + +PKDQ S Sbjct: 209 QGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNG---LRPKDQTS 254
>ADT1_MAIZE (P04709) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 387 Score = 34.7 bits (78), Expect = 0.17 Identities = 34/167 (20%), Positives = 70/167 (41%), Gaps = 8/167 (4%) Frame = +2 Query: 20 DLVKCNMQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKK 199 +++K +P Y+ I F ++++G ++G A ++ Y A F F +YFK+ Sbjct: 120 EMIKSGRLSEP--YKGIVDCFKRTIKDEGFSSLWRGNTANVIRYFPTQALNFAFKDYFKR 177 Query: 200 CYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFAR-------- 355 + + + LA+ +A + + ++ + R+ A+ Sbjct: 178 LF-NFKKDRDGYWKWFAGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGGGERQFN 236 Query: 356 CLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMV 496 L D K ++S+G GLY+G I Y + F +++I +V Sbjct: 237 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVV 283
>ADT_NEUCR (P02723) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 313 Score = 34.3 bits (77), Expect = 0.23 Identities = 32/151 (21%), Positives = 61/151 (40%), Gaps = 8/151 (5%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 +Y I F ++G+ ++G A ++ Y A F F + FKK + + Sbjct: 56 RYNGIIDCFKRTTADEGVMALWRGNTANVIRYFPTQALNFAFRDKFKKMFGYKKDVDGYW 115 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC--------LTDGLPKLVRS 391 + LA+ +A + L + ++ + R+ A+ L D K + S Sbjct: 116 KWMAG-NLASGGAAGATSLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTIAS 174 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 +G GLY+G P + Y + F +++I Sbjct: 175 DGIAGLYRGFGPSVAGIVVYRGLYFGLYDSI 205
>ADT1_YEAST (P04710) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 309 Score = 34.3 bits (77), Expect = 0.23 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 6/115 (5%) Frame = +2 Query: 92 LQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASA 271 L+ GL G ++G++ +++G FG Y+ FK + G ++A+ Sbjct: 172 LKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVL--LTGALEGS------FVASFL 223 Query: 272 SAEVI---ADLALCPMEAVKVRIQTQPGFA---RCLTDGLPKLVRSEGAFGLYKG 418 VI A A P++ V+ R+ G D L K+V+ EGA+ L+KG Sbjct: 224 LGWVITMGASTASYPLDTVRRRMMMTSGQTIKYDGALDCLRKIVQKEGAYSLFKG 278
>UCP1_BOVIN (P10861) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) (Fragment) Length = 288 Score = 33.9 bits (76), Expect = 0.29 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 10/82 (12%) Frame = +2 Query: 275 AEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPK----------LVRSEGAFGLYKGIV 424 A +AD+ P++ KVR+Q Q CL + L ++EG LY G+ Sbjct: 7 AACVADIITFPLDTAKVRLQIQ---GECLISSAIRYKGVLGTIITLAKTEGPVKLYSGLP 63 Query: 425 PLWGRQIPYTMMKFACFETIVE 490 RQI ++ ++T+ E Sbjct: 64 AGLQRQISLASLRIGLYDTVQE 85 Score = 30.8 bits (68), Expect = 2.5 Identities = 38/178 (21%), Positives = 67/178 (37%), Gaps = 14/178 (7%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD K +Q+ +Y+ + L + +G + G A L S + + Sbjct: 17 PLDTAKVRLQIQGECLISSAIRYKGVLGTIITLAKTEGPVKLYSGLPAGLQRQISLASLR 76 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ---- 340 G Y+ ++ ++ G E + K L A I P E VKVR+Q Q Sbjct: 77 IGLYDTVQEFFT--TGKEASLGSKISAGLMTGGVAVFIGQ----PTEVVKVRLQAQSHLH 130 Query: 341 ---PGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKH 505 P + + + +EG GL+KG P + + ++ + E + K+ Sbjct: 131 GPKPRYTGTY-NAYRIIATTEGLTGLWKGTSPNLTTNVIINCTELVTYDLMKEALVKN 187
>LEU5_YEAST (P38702) Mitochondrial carrier protein LEU5| Length = 357 Score = 33.9 bits (76), Expect = 0.29 Identities = 40/187 (21%), Positives = 68/187 (36%), Gaps = 24/187 (12%) Frame = +2 Query: 8 VXPLDLVKCNMQVDPSKYRDISSGFGVLLQ-------EQGLGGFFKGWMATLVGYSSQGA 166 + PLD +K Q Y + L++ G+ GFF+G ATL+ A Sbjct: 51 IAPLDRIKILFQTSNPHYTKYTGSLIGLVEAAKHIWINDGVRGFFQGHSATLLRIFPYAA 110 Query: 167 CKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPG 346 KF YE + E+ R L + + A + + P++ V+VR+ + Sbjct: 111 VKFVAYEQIRNTLIPSKEFESHWR-----RLVSGSLAGLCSVFITYPLDLVRVRLAYETE 165 Query: 347 FARCLTDGLPKLVRSEGA-----------------FGLYKGIVPLWGRQIPYTMMKFACF 475 R + K + E A Y+G VP IPY + F Sbjct: 166 HKRVKLGRIIKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYVPTVLGMIPYAGVSFFAH 225 Query: 476 ETIVEMV 496 + + +++ Sbjct: 226 DLLHDVL 232 Score = 33.1 bits (74), Expect = 0.50 Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 8/72 (11%) Frame = +2 Query: 5 AVXPLDLVKCNMQVDP--------SKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQ 160 A P ++++ +QV K++ IS ++ +E+G+ GFF G + + Sbjct: 281 AAYPFEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERGVRGFFVGLSIGYIKVTPM 340 Query: 161 GACKFGFYEYFK 196 AC F YE K Sbjct: 341 VACSFFVYERMK 352
>UCP1_PHOSU (Q9ER18) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 33.1 bits (74), Expect = 0.50 Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 7/116 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD K +Q+ +Y+ + L + +GL + G A + S + + Sbjct: 33 PLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLR 92 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 G Y+ ++ +S +G E L V ++A +A P E VKVR+Q Q Sbjct: 93 IGLYDTVQEYFS--SGKETPPTL--VNRISAGLMTGGVAVFIGQPTEVVKVRLQAQ 144 Score = 32.7 bits (73), Expect = 0.66 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Frame = +2 Query: 251 IYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT-------DGLPKLVRSEGAFGL 409 + + ++ A +AD+ P++ KVR+Q Q T + L ++EG L Sbjct: 15 VKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGLPKL 74 Query: 410 YKGIVPLWGRQIPYTMMKFACFETIVE 490 Y G+ RQI + ++ ++T+ E Sbjct: 75 YSGLPAGIQRQISFASLRIGLYDTVQE 101 Score = 32.3 bits (72), Expect = 0.86 Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Frame = +2 Query: 305 PMEAVKVR-IQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFET 481 P + VK R I + PG + + EG +KG VP + R + ++ F CFE Sbjct: 232 PADVVKTRFINSLPGQYPSVPSCAMTMFTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQ 291 Query: 482 IVEMVYK 502 + + + K Sbjct: 292 LKKELMK 298
>UCP1_DICGR (Q8K404) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 33.1 bits (74), Expect = 0.50 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Frame = +2 Query: 305 PMEAVKVR-IQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFET 481 P + VK R I + PG + ++ EG +KG VP + R + ++ F CFE Sbjct: 232 PADVVKTRFINSLPGQYPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQ 291 Query: 482 IVEMVYK 502 + + + K Sbjct: 292 LKKELMK 298 Score = 30.8 bits (68), Expect = 2.5 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 7/76 (9%) Frame = +2 Query: 284 IADLALCPMEAVKVRIQTQPGFARCLT-------DGLPKLVRSEGAFGLYKGIVPLWGRQ 442 +AD+ P++ KVR+Q Q T + L ++EG LY G+ RQ Sbjct: 26 LADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGWPKLYSGLPAGIQRQ 85 Query: 443 IPYTMMKFACFETIVE 490 I + ++ ++T+ E Sbjct: 86 ISFASLRIGLYDTVQE 101 Score = 30.0 bits (66), Expect = 4.3 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Frame = +2 Query: 14 PLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 P D+VK + P +Y + S +L ++G FFKG++ + + +S F +E Sbjct: 232 PADVVKTRFINSLPGQYPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQ 291 Query: 191 FKK 199 KK Sbjct: 292 LKK 294 Score = 30.0 bits (66), Expect = 4.3 Identities = 28/116 (24%), Positives = 47/116 (40%), Gaps = 7/116 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD K +Q+ +Y+ + L + +G + G A + S + + Sbjct: 33 PLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGWPKLYSGLPAGIQRQISFASLR 92 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 G Y+ ++ +S +G E L I +A +A P E VKVR+Q Q Sbjct: 93 IGLYDTVQEYFS--SGKETPPTLGNRI--SAGLMTGGVAVFIGQPTEVVKVRLQAQ 144
>UCP1_MESAU (P04575) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 32.7 bits (73), Expect = 0.66 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Frame = +2 Query: 305 PMEAVKVR-IQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFET 481 P + VK R I + PG + ++ EG +KG VP + R + ++ F CFE Sbjct: 231 PADVVKTRFINSLPGQYPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQ 290 Query: 482 IVEMVYK 502 + + + K Sbjct: 291 LKKELSK 297 Score = 32.3 bits (72), Expect = 0.86 Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 7/116 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD K +Q+ +Y+ + L + +GL + G A + S + + Sbjct: 32 PLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLR 91 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 G Y+ ++ +S +G E L I +A +A P E VKVR+Q Q Sbjct: 92 IGLYDTVQEYFS--SGKETPPTLGNRI--SAGLMTGGVAVFIGQPTEVVKVRLQAQ 143 Score = 32.0 bits (71), Expect = 1.1 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Frame = +2 Query: 251 IYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCLT-------DGLPKLVRSEGAFGL 409 + + ++ A +AD+ P++ KVR+Q Q T + L ++EG L Sbjct: 14 VKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGLPKL 73 Query: 410 YKGIVPLWGRQIPYTMMKFACFETIVE 490 Y G+ RQI + ++ ++T+ E Sbjct: 74 YSGLPAGIQRQISFASLRIGLYDTVQE 100 Score = 30.0 bits (66), Expect = 4.3 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Frame = +2 Query: 14 PLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEY 190 P D+VK + P +Y + S +L ++G FFKG++ + + +S F +E Sbjct: 231 PADVVKTRFINSLPGQYPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQ 290 Query: 191 FKK 199 KK Sbjct: 291 LKK 293
>YQ51_CAEEL (Q09461) Putative mitochondrial carrier C16C10.1| Length = 360 Score = 32.3 bits (72), Expect = 0.86 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 5/66 (7%) Frame = +2 Query: 14 PLDLVKCNMQVD-----PSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 P D++K N Q+ + I++ + +G+ F G + LV S A Sbjct: 288 PFDVIKTNCQIRIGGSIDDMNKSITTVIKDMYHSRGISAFSSGLVPRLVKVSPSCAIMIS 347 Query: 179 FYEYFK 196 FYEYFK Sbjct: 348 FYEYFK 353
>YE08_SCHPO (O13805) Putative mitochondrial carrier C17H9.08| Length = 326 Score = 32.3 bits (72), Expect = 0.86 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Frame = +2 Query: 263 ASASAEVIADLALCPMEAVKVRIQTQPGFARCLT---DGLPKLVRS----EGAFGLYKGI 421 A +A +A + P++ VK+ QT R GL K ++ G GLY+G Sbjct: 23 AGGTAGCVAKSVVAPLDRVKILYQTNHASYRGYAYSRHGLYKAIKHIYHVYGLHGLYQGH 82 Query: 422 VPLWGRQIPYTMMKFACFETI 484 R PY +KF +E + Sbjct: 83 TATLYRVFPYAGIKFVAYEQV 103
>YG5F_YEAST (P53320) Putative mitochondrial carrier YGR257C| Length = 366 Score = 32.0 bits (71), Expect = 1.1 Identities = 17/78 (21%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Frame = +2 Query: 257 LAASASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWG 436 + ++ + V+ L L PM+ V++R+Q Q C DG ++ + + K + G Sbjct: 16 MLSAGAGSVLTSLILTPMDVVRIRLQQQQMIPDCSCDGAAEVPNAVSSGSKMKTFTNVGG 75 Query: 437 RQIPYTMM--KFACFETI 484 + + + + ACF+ + Sbjct: 76 QNLNNAKIFWESACFQEL 93
>UCP1_RAT (P04633) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 32.0 bits (71), Expect = 1.1 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Frame = +2 Query: 254 YLAASASAEVIADLALCPMEAVKVR-IQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPL 430 +L ++ A L P++ VK R I + PG + + EG +KG P Sbjct: 214 HLLSALVAGFCTTLLASPVDVVKTRFINSLPGQYPSVPSCAMTMYTKEGPAAFFKGFAPS 273 Query: 431 WGRQIPYTMMKFACFETIVEMVYK 502 + R + ++ F CFE + + + K Sbjct: 274 FLRLGSWNVIMFVCFEQLKKELMK 297 Score = 32.0 bits (71), Expect = 1.1 Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 7/116 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD K +Q+ +Y+ + L + +GL + G A + S + + Sbjct: 32 PLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLR 91 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 G Y+ ++ +S +G E L + I +A +A P E VKVR+Q Q Sbjct: 92 IGLYDTVQEYFS--SGRETPASLGSKI--SAGLMTGGVAVFIGQPTEVVKVRMQAQ 143 Score = 32.0 bits (71), Expect = 1.1 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 7/76 (9%) Frame = +2 Query: 284 IADLALCPMEAVKVRIQTQ-PGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQ 442 +AD+ P++ KVR+Q Q G A + + + L ++EG LY G+ RQ Sbjct: 25 LADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQ 84 Query: 443 IPYTMMKFACFETIVE 490 I + ++ ++T+ E Sbjct: 85 ISFASLRIGLYDTVQE 100 Score = 29.6 bits (65), Expect = 5.6 Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Frame = +2 Query: 2 LAVXPLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 L P+D+VK + P +Y + S + ++G FFKG+ + + S F Sbjct: 227 LLASPVDVVKTRFINSLPGQYPSVPSCAMTMYTKEGPAAFFKGFAPSFLRLGSWNVIMFV 286 Query: 179 FYEYFKK 199 +E KK Sbjct: 287 CFEQLKK 293
>UCP1_MOUSE (P12242) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 32.0 bits (71), Expect = 1.1 Identities = 36/170 (21%), Positives = 65/170 (38%), Gaps = 7/170 (4%) Frame = +2 Query: 14 PLDLVKCNMQVDPS------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKF 175 P ++VK MQ +Y + + V+ + L +KG L+ + Sbjct: 132 PTEVVKVRMQAQSHLHGIKPRYTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTEL 191 Query: 176 GFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR-IQTQPGFA 352 Y+ K + AD + +L ++ A L P++ VK R I + PG Sbjct: 192 VTYDLMKGAL--VNNKILADDVPC--HLLSALVAGFCTTLLASPVDVVKTRFINSLPGQY 247 Query: 353 RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYK 502 + + EG +KG V + R + ++ F CFE + + + K Sbjct: 248 PSVPSCAMSMYTKEGPTAFFKGFVASFLRLGSWNVIMFVCFEQLKKELMK 297 Score = 31.6 bits (70), Expect = 1.5 Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 7/116 (6%) Frame = +2 Query: 14 PLDLVKCNMQVDPS-------KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACK 172 PLD K +Q+ +Y+ + L + +GL + G A + S + + Sbjct: 32 PLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLR 91 Query: 173 FGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQ 340 G Y+ ++ +S +G E L I +A +A P E VKVR+Q Q Sbjct: 92 IGLYDSVQEYFS--SGRETPASLGNKI--SAGLMTGGVAVFIGQPTEVVKVRMQAQ 143 Score = 30.8 bits (68), Expect = 2.5 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Frame = +2 Query: 2 LAVXPLDLVKCN-MQVDPSKYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFG 178 L P+D+VK + P +Y + S + ++G FFKG++A+ + S F Sbjct: 227 LLASPVDVVKTRFINSLPGQYPSVPSCAMSMYTKEGPTAFFKGFVASFLRLGSWNVIMFV 286 Query: 179 FYEYFKK 199 +E KK Sbjct: 287 CFEQLKK 293 Score = 30.4 bits (67), Expect = 3.3 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 7/76 (9%) Frame = +2 Query: 284 IADLALCPMEAVKVRIQTQ-PGFA------RCLTDGLPKLVRSEGAFGLYKGIVPLWGRQ 442 +AD+ P++ KVR+Q Q G A + + + L ++EG LY G+ RQ Sbjct: 25 LADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQ 84 Query: 443 IPYTMMKFACFETIVE 490 I + ++ ++++ E Sbjct: 85 ISFASLRIGLYDSVQE 100
>ADT_KLULA (P49382) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 305 Score = 32.0 bits (71), Expect = 1.1 Identities = 31/151 (20%), Positives = 60/151 (39%), Gaps = 8/151 (5%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFKKCYSDIAGPENAD 235 +Y I F ++G+ F++G A ++ Y A F F + K + E Sbjct: 53 RYTGIVECFKRTAADEGVASFWRGNTANVIRYFPTQALNFAFKDKIKAMFG--FKKEEGY 110 Query: 236 RLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARC--------LTDGLPKLVRS 391 LA+ A ++ L + ++ + R+ A+ L D K + S Sbjct: 111 AKWFAGNLASGGLAGGLSLLFVYSLDYARTRLAADSKSAKKGGERQFNGLVDVYKKTLAS 170 Query: 392 EGAFGLYKGIVPLWGRQIPYTMMKFACFETI 484 +G GLY+G +P + Y + F ++++ Sbjct: 171 DGVAGLYRGFLPSVVGIVVYRGLYFGLYDSL 201
>ADA17_HUMAN (P78536) ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and| metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen) Length = 824 Score = 31.6 bits (70), Expect = 1.5 Identities = 27/107 (25%), Positives = 38/107 (35%) Frame = +1 Query: 214 CWPRECRQVEDRHLPRCIGVG*GNCRFSSLPHGSRQGSNPDAAGIRSMPNRWASKACPVR 393 C +E Q DR+ P C NC+F + ++ N G+ Sbjct: 506 CTLKEGVQCSDRNSPCC-----KNCQFETAQKKCQEAINATCKGVSYCT----------- 549 Query: 394 RCLWALQGDSSSLGPPNSLHYDEICLL*NHC*DGVQACCPKTKRSMQ 534 G+SS PP + D +CL C DG C P +R Q Sbjct: 550 -------GNSSECPPPGNAEDDTVCLDLGKCKDG--KCIPFCEREQQ 587
>GRPE_PICTO (Q6L0S8) Protein grpE (HSP-70 cofactor)| Length = 180 Score = 30.4 bits (67), Expect = 3.3 Identities = 17/66 (25%), Positives = 33/66 (50%) Frame = +2 Query: 149 YSSQGACKFGFYEYFKKCYSDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVR 328 Y Q + + Y +K ++I NAD +KT++ + S A ++ D L P+ + ++ Sbjct: 52 YMRQRSEMENYQRYIEKTINNIKANANADLIKTMLPVLDSLDAGILHDEKLKPIRSQLIK 111 Query: 329 IQTQPG 346 I + G Sbjct: 112 ILSNYG 117
>ECEL1_MOUSE (Q9JMI0) Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce| protein) (Damage-induced neuronal endopeptidase) Length = 775 Score = 30.4 bits (67), Expect = 3.3 Identities = 18/43 (41%), Positives = 24/43 (55%) Frame = +1 Query: 241 EDRHLPRCIGVG*GNCRFSSLPHGSRQGSNPDAAGIRSMPNRW 369 E +++ RC G G R +SLP G +GS A+G RS RW Sbjct: 16 EVKYVSRC---GTGGARGTSLPPGFPRGSGRSASGSRSGLPRW 55
>YIHP_ECOLI (P32137) Inner membrane symporter yihP| Length = 461 Score = 30.0 bits (66), Expect = 4.3 Identities = 11/17 (64%), Positives = 12/17 (70%) Frame = +2 Query: 101 QGLGGFFKGWMATLVGY 151 Q L GFF GWM T +GY Sbjct: 387 QALAGFFPGWMLTQIGY 403
>YIHP_SALTY (Q9L7R5) Inner membrane symporter yihP| Length = 460 Score = 30.0 bits (66), Expect = 4.3 Identities = 11/17 (64%), Positives = 12/17 (70%) Frame = +2 Query: 101 QGLGGFFKGWMATLVGY 151 Q L GFF GWM T +GY Sbjct: 386 QALAGFFPGWMLTQIGY 402
>MTCH1_MOUSE (Q791T5) Mitochondrial carrier homolog 1 (Mitochondrial| carrier-like protein 1) Length = 389 Score = 29.6 bits (65), Expect = 5.6 Identities = 13/32 (40%), Positives = 20/32 (62%) Frame = +2 Query: 53 SKYRDISSGFGVLLQEQGLGGFFKGWMATLVG 148 +KY + S G + +E+GL GFF G + L+G Sbjct: 231 AKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLG 262
>MTCH1_HUMAN (Q9NZJ7) Mitochondrial carrier homolog 1 (Presenilin-associated| protein) Length = 389 Score = 29.6 bits (65), Expect = 5.6 Identities = 13/32 (40%), Positives = 20/32 (62%) Frame = +2 Query: 53 SKYRDISSGFGVLLQEQGLGGFFKGWMATLVG 148 +KY + S G + +E+GL GFF G + L+G Sbjct: 231 AKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLG 262
>MFRN_CAEBR (Q620A6) Mitoferrin| Length = 311 Score = 29.6 bits (65), Expect = 5.6 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 16/77 (20%) Frame = +2 Query: 14 PLDLVKCNM------QVDPS----------KYRDISSGFGVLLQEQGLGGFFKGWMATLV 145 P+D VK + + DPS +YR IS + ++G+ GF G A ++ Sbjct: 224 PMDCVKTVLNTQQAAEADPSNRRIFLKARYRYRGISDAVRTIYSQRGMAGFSCGLQARVI 283 Query: 146 GYSSQGACKFGFYEYFK 196 A + YE FK Sbjct: 284 FQVPATALSWSVYELFK 300
>MFRN_CAEEL (Q23125) Mitoferrin| Length = 312 Score = 29.6 bits (65), Expect = 5.6 Identities = 15/47 (31%), Positives = 22/47 (46%) Frame = +2 Query: 56 KYRDISSGFGVLLQEQGLGGFFKGWMATLVGYSSQGACKFGFYEYFK 196 +YR IS + ++GL GF G A ++ A + YE FK Sbjct: 255 RYRGISDAVRTIYSQRGLSGFSCGLQARVIFQVPATALSWSVYELFK 301
>ANT3_CHICK (Q03352) Antithrombin-III precursor (ATIII) (Fragment)| Length = 105 Score = 29.6 bits (65), Expect = 5.6 Identities = 22/65 (33%), Positives = 30/65 (46%) Frame = -3 Query: 419 SPCKAQRHLRTGQALEAHRLGIERIPAASGFEP*RLPWGRELNLQLPQPTPMQRGK*RSS 240 +P K + R A E G+ + PA+ +GR LQ P PTP R R+S Sbjct: 43 NPEKKPQERRGAGAGEGQDPGVHKPPASGSCPGPTRAFGRRSFLQAPGPTP--RTMRRTS 100 Query: 239 TCRHS 225 +CR S Sbjct: 101 SCRPS 105
>PHF1_MOUSE (Q9Z1B8) PHD finger protein 1 (PHF1 protein) (T-complex| testis-expressed 3) (Polycomblike 1) (mPCl1) Length = 559 Score = 29.3 bits (64), Expect = 7.3 Identities = 16/50 (32%), Positives = 21/50 (42%) Frame = +1 Query: 304 PHGSRQGSNPDAAGIRSMPNRWASKACPVRRCLWALQGDSSSLGPPNSLH 453 P G P R + RW S+ P+RR +G LGPP + H Sbjct: 348 PTSFPSGQGPGGGVSRPLGKRWRSEPEPLRR---RQKGKVEELGPPTAAH 394
>BIRC2_MOUSE (Q62210) Baculoviral IAP repeat-containing protein 2 (Inhibitor of| apoptosis protein 2) (MIAP2) (MIAP-2) Length = 612 Score = 29.3 bits (64), Expect = 7.3 Identities = 18/52 (34%), Positives = 27/52 (51%) Frame = +2 Query: 206 SDIAGPENADRLKTVIYLAASASAEVIADLALCPMEAVKVRIQTQPGFARCL 361 SD G ENAD +TV++ S+E D+ + VK ++ GF+R L Sbjct: 356 SDTPGEENADPTETVVHFGPGESSE---DVVMMSTPVVKAALEM--GFSRSL 402
>MUC5A_HUMAN (P98088) Mucin-5AC (Mucin 5 subtype AC, tracheobronchial)| (Tracheobronchial mucin) (TBM) (Major airway glycoprotein) (Fragment) Length = 1233 Score = 29.3 bits (64), Expect = 7.3 Identities = 11/42 (26%), Positives = 20/42 (47%) Frame = +1 Query: 343 GIRSMPNRWASKACPVRRCLWALQGDSSSLGPPNSLHYDEIC 468 G R++P CPV+ C W + + +L P ++ +C Sbjct: 939 GARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSLC 980
>YRD6_CAEEL (Q09575) Hypothetical protein K02A2.6| Length = 1268 Score = 29.3 bits (64), Expect = 7.3 Identities = 18/85 (21%), Positives = 35/85 (41%) Frame = +2 Query: 266 SASAEVIADLALCPMEAVKVRIQTQPGFARCLTDGLPKLVRSEGAFGLYKGIVPLWGRQI 445 SA A+++ ++ EA ++ + + F DGL + + F + VP++ R Sbjct: 387 SALAQIVNQVSTSETEASRLEVMLKNDFPEVFKDGLGLCTKEKAEFRTEENAVPVFKRAR 446 Query: 446 PYTMMKFACFETIVEMVYKHAVPKP 520 P ET + + + V P Sbjct: 447 PVPYGSLEAVETELNRLQEMGVIVP 471
>POLG_HCVJK (Q68801) Genome polyprotein [Contains: Core protein p21 (Capsid| protein C) (p21); Core protein p19; Envelope glycoprotein E1 (gp32) (gp35); Envelope glycoprotein E2 (NS1) (gp68) (gp70); p7; Protease NS2-3 (EC 3.4.22.-) (p23); Serine protease/N Length = 3018 Score = 28.9 bits (63), Expect = 9.5 Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 3/110 (2%) Frame = -2 Query: 399 APSDRTS--FGSPSVRHRANPGCVWIRTLTASMGQRAKSAITSADADAAR*MTVFNLSAF 226 +P +R S F S + + GC W + R ++ +++ + F F Sbjct: 1507 SPGERPSGMFDSVVLCECYDAGCAWYELTPSETTVRLRAYLSTPGLPVCQDHLEFWEGVF 1566 Query: 225 SGPAMSE*HFLKYS*KPNLQAPWL-LYPTSVAIQPLKNPPRPCSWSSTPK 79 +G + HFL + + L P+L Y +V + PP SW T K Sbjct: 1567 TGLTHIDAHFLSQTKQQGLNFPYLTAYQATVCARAAALPP---SWDETWK 1613
>PLCL4_HUMAN (O75038) 1-phosphatidylinositol-4,5-bisphosphate| phosphodiesterase-like 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-like 4) (Phospholipase C-like 4) (Fragment) Length = 1182 Score = 28.9 bits (63), Expect = 9.5 Identities = 17/40 (42%), Positives = 21/40 (52%) Frame = +1 Query: 313 SRQGSNPDAAGIRSMPNRWASKACPVRRCLWALQGDSSSL 432 S S+PD+ GI RW AC R ALQG+ S+L Sbjct: 1126 SSDSSSPDSPGIPERSPRWPEGAC---RQPGALQGEMSAL 1162
>MCAR1_MOUSE (Q5HZI9) Mitochondrial carrier triple repeat 1| Length = 298 Score = 28.9 bits (63), Expect = 9.5 Identities = 12/47 (25%), Positives = 25/47 (53%) Frame = +2 Query: 383 VRSEGAFGLYKGIVPLWGRQIPYTMMKFACFETIVEMVYKHAVPKPK 523 +R +G LY+GI+P ++ + F +E + +++KH P+ Sbjct: 72 LRKDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSRLLHKHVSSAPE 118
>HN_HENDV (O89343) Hemagglutinin-neuraminidase (EC 3.2.1.18)| Length = 604 Score = 28.9 bits (63), Expect = 9.5 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Frame = -1 Query: 334 LDSNLDG-FHGAES*ICNYLSRRRCSEVNDGLQPVGILGASNVRVALLEVLV 182 L++NL G I NY ++NDGL ILGA N +ALL ++ Sbjct: 10 LNNNLSGKIKDQGKVIKNYYGTMDIKKINDGLLDSKILGAFNTVIALLGSII 61 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,642,723 Number of Sequences: 219361 Number of extensions: 1954053 Number of successful extensions: 6266 Number of sequences better than 10.0: 186 Number of HSP's better than 10.0 without gapping: 5674 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6104 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4200495993 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
