>LGUL_ORYSA (Q948T6) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
           (Allergen Ory s ?) (Allergen Glb33) (PP33)
          Length = 291

 Score =  370 bits (950), Expect = e-102
 Identities = 177/193 (91%), Positives = 184/193 (95%)
 Frame = +1

Query: 118 MATGSEAGKSAEAVLEWPKQDKKRMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEK 297
           MA+GSEA KS E VLEWPK+DKKR+LHAVYRVGDLD+TIKCYTECFGMKLLRKRDVPEEK
Sbjct: 1   MASGSEAEKSPEVVLEWPKKDKKRLLHAVYRVGDLDRTIKCYTECFGMKLLRKRDVPEEK 60

Query: 298 YTNAFLGFGPEDTNFALELTYNYGVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKIT 477
           YTNAFLGFGPEDTNFALELTYNYGVDKYDIGAGFGHFAIA EDVYKL+E IKSS CCKIT
Sbjct: 61  YTNAFLGFGPEDTNFALELTYNYGVDKYDIGAGFGHFAIATEDVYKLAEKIKSSCCCKIT 120

Query: 478 REPGPVKGGSTVIAFAQDPDGYLFELIQRGPTPEPLCQVMLRVGDLDRAIMFYEKALGMK 657
           REPGPVKGGSTVIAFAQDPDGY+FELIQRGPTPEPLCQVMLRVGDLDR+I FYEKALGMK
Sbjct: 121 REPGPVKGGSTVIAFAQDPDGYMFELIQRGPTPEPLCQVMLRVGDLDRSIKFYEKALGMK 180

Query: 658 LLRKXDVPQYKYT 696
           LLRK DVP YKYT
Sbjct: 181 LLRKKDVPDYKYT 193



 Score =  114 bits (286), Expect = 2e-25
 Identities = 60/126 (47%), Positives = 79/126 (62%), Gaps = 3/126 (2%)
 Frame = +1

Query: 190 MLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNYG 369
           +   + RVGDLD++IK Y +  GMKLLRK+DVP+ KYT A LG+  ED    +ELTYNYG
Sbjct: 156 LCQVMLRVGDLDRSIKFYEKALGMKLLRKKDVPDYKYTIAMLGYADEDKTTVIELTYNYG 215

Query: 370 VDKYDIGAGFGHFAIANEDVYKLSETIK---SSDCCKITREPGPVKGGSTVIAFAQDPDG 540
           V +Y  G  +   AI  EDVYK +E ++        KI R+PGP+ G +T IA   DPDG
Sbjct: 216 VTEYTKGNAYAQVAIGTEDVYKSAEAVELVTKELGGKILRQPGPLPGLNTKIASFLDPDG 275

Query: 541 YLFELI 558
           +   L+
Sbjct: 276 WKVVLV 281

>LGUL_BRAOG (Q39366) Putative lactoylglutathione lyase (EC 4.4.1.5)|
           (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx
           I) (Ketone-aldehyde mutase) (S-D-lactoylglutathione
           methylglyoxal lyase)
          Length = 282

 Score =  280 bits (716), Expect = 3e-75
 Identities = 129/177 (72%), Positives = 153/177 (86%)
 Frame = +1

Query: 157 VLEWPKQDKKRMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDT 336
           ++EWPK+DK+R LH VYRVGDLD+TI+ YTECFGMK+LRKRDVPEEKY+NAFLGFGPE +
Sbjct: 7   LVEWPKKDKRRFLHVVYRVGDLDRTIQFYTECFGMKVLRKRDVPEEKYSNAFLGFGPETS 66

Query: 337 NFALELTYNYGVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVI 516
           NF +ELTYNYGV  YDIG GFGHFAI+ +DV K+ E +++     +TREPGPVKGG +VI
Sbjct: 67  NFVVELTYNYGVSSYDIGTGFGHFAISTQDVSKMVEAVRAKG-GNVTREPGPVKGGGSVI 125

Query: 517 AFAQDPDGYLFELIQRGPTPEPLCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQY 687
           AF +DPDGY FELIQRGPTPEPLCQVMLRVGDLDRA+ F EKALGM+LLR+ + P+Y
Sbjct: 126 AFVKDPDGYTFELIQRGPTPEPLCQVMLRVGDLDRAVKFMEKALGMRLLRRIERPEY 182



 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 50/121 (41%), Positives = 69/121 (57%), Gaps = 3/121 (2%)
 Frame = +1

Query: 190 MLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNYG 369
           +   + RVGDLD+ +K   +  GM+LLR+ + PE   T   +G+  E  +  LELTYNYG
Sbjct: 148 LCQVMLRVGDLDRAVKFMEKALGMRLLRRIERPEYN-TIGMMGYAEEYESIVLELTYNYG 206

Query: 370 VDKYDIGAGFGHFAIANEDVYKLSETIKSSD---CCKITREPGPVKGGSTVIAFAQDPDG 540
           V +Y  G  +   AI  +DVYK +E +K  +     KITRE GP+ G  T I    DPDG
Sbjct: 207 VTEYTKGNAYAQIAIGTDDVYKSAEVVKIVNQELGGKITREAGPLPGLGTKIVSFLDPDG 266

Query: 541 Y 543
           +
Sbjct: 267 W 267



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 22/35 (62%), Positives = 27/35 (77%)
 Frame = +1

Query: 592 VMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           V+ RVGDLDR I FY +  GMK+LRK DVP+ KY+
Sbjct: 21  VVYRVGDLDRTIQFYTECFGMKVLRKRDVPEEKYS 55

>LGUL_SYNY3 (Q55595) Probable lactoylglutathione lyase (EC 4.4.1.5)|
           (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx
           I) (Ketone-aldehyde mutase) (S-D-lactoylglutathione
           methylglyoxal lyase)
          Length = 131

 Score =  144 bits (362), Expect = 3e-34
 Identities = 66/124 (53%), Positives = 89/124 (71%)
 Frame = +1

Query: 190 MLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNYG 369
           +LH + RVGDLDK+++ Y +  GM LLRK+D P  ++T AF+G+G E  N  +ELT+N+G
Sbjct: 3   LLHTMIRVGDLDKSLQFYCDILGMNLLRKKDYPSGEFTLAFVGYGKESENAVIELTHNWG 62

Query: 370 VDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYLF 549
            DKYD+G GFGH A+  ED+Y   + I+     K+ REPGP+K G+TVIAF +DPDGY  
Sbjct: 63  TDKYDLGNGFGHIALGVEDIYSTCDKIRDKG-GKVVREPGPMKHGTTVIAFVEDPDGYKI 121

Query: 550 ELIQ 561
           ELIQ
Sbjct: 122 ELIQ 125



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 20/38 (52%), Positives = 26/38 (68%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   M+RVGDLD+++ FY   LGM LLRK D P  ++T
Sbjct: 3   LLHTMIRVGDLDKSLQFYCDILGMNLLRKKDYPSGEFT 40

>LGUL_VIBCH (Q9KT93) Probable lactoylglutathione lyase (EC 4.4.1.5)|
           (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx
           I) (Ketone-aldehyde mutase) (S-D-lactoylglutathione
           methylglyoxal lyase)
          Length = 184

 Score =  143 bits (360), Expect = 6e-34
 Identities = 70/125 (56%), Positives = 90/125 (72%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVGDLDK+I+ YT+  GM LLRK +  E KYT AFLG+G E     +ELTYN+
Sbjct: 51  RILHTMLRVGDLDKSIEFYTQVMGMSLLRKNENTEYKYTLAFLGYGDESQGAVIELTYNW 110

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           GV  Y+ G  +GH AI  +D+Y   +TIK++    +TREPGPVKGG+T IAF +DPDGY+
Sbjct: 111 GVADYEKGNAYGHIAIGVDDIYATCDTIKAAGGI-VTREPGPVKGGTTHIAFVKDPDGYM 169

Query: 547 FELIQ 561
            ELIQ
Sbjct: 170 IELIQ 174



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 21/38 (55%), Positives = 28/38 (73%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           +   MLRVGDLD++I FY + +GM LLRK +  +YKYT
Sbjct: 52  ILHTMLRVGDLDKSIEFYTQVMGMSLLRKNENTEYKYT 89

>LGUL_VIBPA (P46235) Probable lactoylglutathione lyase (EC 4.4.1.5)|
           (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx
           I) (Ketone-aldehyde mutase) (S-D-lactoylglutathione
           methylglyoxal lyase)
          Length = 138

 Score =  140 bits (354), Expect = 3e-33
 Identities = 68/125 (54%), Positives = 89/125 (71%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVGDLDK+IK YTE  GM+LLR  +  E +YT AF+G+G E     +ELTYN+
Sbjct: 5   RILHTMLRVGDLDKSIKFYTEVMGMQLLRTNENKEYEYTLAFVGYGDESQGAVIELTYNW 64

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           G  +YD+G  FGH AI  +D+Y   + IK++    +TRE GPVKGG+T IAF +DPDGY+
Sbjct: 65  GKTEYDLGTAFGHIAIGVDDIYATCDAIKAAG-GNVTREAGPVKGGTTHIAFVKDPDGYM 123

Query: 547 FELIQ 561
            ELIQ
Sbjct: 124 IELIQ 128



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 19/38 (50%), Positives = 28/38 (73%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           +   MLRVGDLD++I FY + +GM+LLR  +  +Y+YT
Sbjct: 6   ILHTMLRVGDLDKSIKFYTEVMGMQLLRTNENKEYEYT 43

>LGUL_HAEIN (P44638) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 135

 Score =  139 bits (349), Expect = 1e-32
 Identities = 68/133 (51%), Positives = 91/133 (68%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           ++LH + RVGDLD++IK Y +  GM+LLR  + PE KYT AFLG+   ++   +ELTYN+
Sbjct: 2   QILHTMLRVGDLDRSIKFYQDVLGMRLLRTSENPEYKYTLAFLGYEDGESAAEIELTYNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           GVDKY+ G  +GH AI  +D+Y   E +++S    +TRE GPVKGGSTVIAF +DPDGY 
Sbjct: 62  GVDKYEHGTAYGHIAIGVDDIYATCEAVRASG-GNVTREAGPVKGGSTVIAFVEDPDGYK 120

Query: 547 FELIQRGPTPEPL 585
            E I+   T   L
Sbjct: 121 IEFIENKSTKSGL 133



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 23/38 (60%), Positives = 29/38 (76%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           +   MLRVGDLDR+I FY+  LGM+LLR  + P+YKYT
Sbjct: 3   ILHTMLRVGDLDRSIKFYQDVLGMRLLRTSENPEYKYT 40

>LGUL_SHIFL (P0AC83) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 135

 Score =  138 bits (347), Expect = 2e-32
 Identities = 65/125 (52%), Positives = 90/125 (72%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVGDL ++I  YT+  GMKLLR  + PE KY+ AF+G+GPE     +ELTYN+
Sbjct: 2   RLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           GVDKY++G  +GH A++ ++  +  E I+ +    +TRE GPVKGG+TVIAF +DPDGY 
Sbjct: 62  GVDKYELGTAYGHIALSVDNAAEACEKIRQNG-GNVTREAGPVKGGTTVIAFVEDPDGYK 120

Query: 547 FELIQ 561
            ELI+
Sbjct: 121 IELIE 125



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 24/38 (63%), Positives = 28/38 (73%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   MLRVGDL R+I FY K LGMKLLR  + P+YKY+
Sbjct: 3   LLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYS 40

>LGUL_ECOLI (P0AC81) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 135

 Score =  138 bits (347), Expect = 2e-32
 Identities = 65/125 (52%), Positives = 90/125 (72%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVGDL ++I  YT+  GMKLLR  + PE KY+ AF+G+GPE     +ELTYN+
Sbjct: 2   RLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           GVDKY++G  +GH A++ ++  +  E I+ +    +TRE GPVKGG+TVIAF +DPDGY 
Sbjct: 62  GVDKYELGTAYGHIALSVDNAAEACEKIRQNG-GNVTREAGPVKGGTTVIAFVEDPDGYK 120

Query: 547 FELIQ 561
            ELI+
Sbjct: 121 IELIE 125



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 24/38 (63%), Positives = 28/38 (73%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   MLRVGDL R+I FY K LGMKLLR  + P+YKY+
Sbjct: 3   LLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYS 40

>LGUL_ECO57 (P0AC82) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 135

 Score =  138 bits (347), Expect = 2e-32
 Identities = 65/125 (52%), Positives = 90/125 (72%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVGDL ++I  YT+  GMKLLR  + PE KY+ AF+G+GPE     +ELTYN+
Sbjct: 2   RLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           GVDKY++G  +GH A++ ++  +  E I+ +    +TRE GPVKGG+TVIAF +DPDGY 
Sbjct: 62  GVDKYELGTAYGHIALSVDNAAEACEKIRQNG-GNVTREAGPVKGGTTVIAFVEDPDGYK 120

Query: 547 FELIQ 561
            ELI+
Sbjct: 121 IELIE 125



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 24/38 (63%), Positives = 28/38 (73%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   MLRVGDL R+I FY K LGMKLLR  + P+YKY+
Sbjct: 3   LLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYS 40

>LGUL_SALTY (P0A1Q2) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 135

 Score =  135 bits (340), Expect = 1e-31
 Identities = 64/125 (51%), Positives = 88/125 (70%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVGDL ++I  YT   GMKLLR  + PE KY+ AF+G+GPE     +ELTYN+
Sbjct: 2   RLLHTMLRVGDLQRSIAFYTNVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           GV+ YD+G  +GH A++ ++  +  E I+ +    +TRE GPVKGGST+IAF +DPDGY 
Sbjct: 62  GVESYDMGNAYGHIALSVDNAAEACERIRQNG-GNVTREAGPVKGGSTIIAFVEDPDGYK 120

Query: 547 FELIQ 561
            ELI+
Sbjct: 121 IELIE 125



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 23/38 (60%), Positives = 27/38 (71%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   MLRVGDL R+I FY   LGMKLLR  + P+YKY+
Sbjct: 3   LLHTMLRVGDLQRSIAFYTNVLGMKLLRTSENPEYKYS 40

>LGUL_SALTI (P0A1Q3) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 135

 Score =  135 bits (340), Expect = 1e-31
 Identities = 64/125 (51%), Positives = 88/125 (70%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVGDL ++I  YT   GMKLLR  + PE KY+ AF+G+GPE     +ELTYN+
Sbjct: 2   RLLHTMLRVGDLQRSIAFYTNVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
           GV+ YD+G  +GH A++ ++  +  E I+ +    +TRE GPVKGGST+IAF +DPDGY 
Sbjct: 62  GVESYDMGNAYGHIALSVDNAAEACERIRQNG-GNVTREAGPVKGGSTIIAFVEDPDGYK 120

Query: 547 FELIQ 561
            ELI+
Sbjct: 121 IELIE 125



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 23/38 (60%), Positives = 27/38 (71%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   MLRVGDL R+I FY   LGMKLLR  + P+YKY+
Sbjct: 3   LLHTMLRVGDLQRSIAFYTNVLGMKLLRTSENPEYKYS 40

>LGUL_NEIMB (P0A0T3) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 138

 Score =  127 bits (319), Expect = 3e-29
 Identities = 58/126 (46%), Positives = 86/126 (68%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVG+L+K++  Y    GMKLLR++D PE ++T AF+G+G E  +  LELT+N+
Sbjct: 2   RLLHTMLRVGNLEKSLDFYQNVLGMKLLRRKDYPEGRFTLAFVGYGDETDSTVLELTHNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
             ++YD+G  +GH A+  +D Y+  E +K      + RE GP+K G+TVIAF +DPDGY 
Sbjct: 62  DTERYDLGNAYGHIAVEVDDAYEACERVKRQG-GNVVREAGPMKHGTTVIAFVEDPDGYK 120

Query: 547 FELIQR 564
            E IQ+
Sbjct: 121 IEFIQK 126



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 19/38 (50%), Positives = 29/38 (76%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   MLRVG+L++++ FY+  LGMKLLR+ D P+ ++T
Sbjct: 3   LLHTMLRVGNLEKSLDFYQNVLGMKLLRRKDYPEGRFT 40

>LGUL_NEIMA (P0A0T2) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 138

 Score =  127 bits (319), Expect = 3e-29
 Identities = 58/126 (46%), Positives = 86/126 (68%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNY 366
           R+LH + RVG+L+K++  Y    GMKLLR++D PE ++T AF+G+G E  +  LELT+N+
Sbjct: 2   RLLHTMLRVGNLEKSLDFYQNVLGMKLLRRKDYPEGRFTLAFVGYGDETDSTVLELTHNW 61

Query: 367 GVDKYDIGAGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVKGGSTVIAFAQDPDGYL 546
             ++YD+G  +GH A+  +D Y+  E +K      + RE GP+K G+TVIAF +DPDGY 
Sbjct: 62  DTERYDLGNAYGHIAVEVDDAYEACERVKRQG-GNVVREAGPMKHGTTVIAFVEDPDGYK 120

Query: 547 FELIQR 564
            E IQ+
Sbjct: 121 IEFIQK 126



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 19/38 (50%), Positives = 29/38 (76%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L   MLRVG+L++++ FY+  LGMKLLR+ D P+ ++T
Sbjct: 3   LLHTMLRVGNLEKSLDFYQNVLGMKLLRRKDYPEGRFT 40

>LGUL_YEAST (P50107) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 326

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 66/199 (33%), Positives = 93/199 (46%), Gaps = 32/199 (16%)
 Frame = +1

Query: 196 HAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPED-------------T 336
           H   RV D  +T+K YTE FGMKLL ++D  E K++  FL F  +D              
Sbjct: 25  HTCLRVKDPARTVKFYTEHFGMKLLSRKDFEEAKFSLYFLSFPKDDIPKNKNGEPDVFSA 84

Query: 337 NFALELTYNYGVDK---YDIG-------AGFGHFAIANEDVYKLSETIKSSDCCKITREP 486
           +  LELT+N+G +K   Y I         GFGH   +  D+ K  E ++S     +  + 
Sbjct: 85  HGVLELTHNWGTEKNPDYKINNGNEEPHRGFGHICFSVSDINKTCEELESQG---VKFKK 141

Query: 487 GPVKGGSTVIAFAQDPDGYLFELI---------QRGPTPEPLCQVMLRVGDLDRAIMFYE 639
              +G    IAFA  PDGY  ELI          +G         M+R+ +  R++ FY+
Sbjct: 142 RLSEGRQKDIAFALGPDGYWIELITYSREGQEYPKGSVGNKFNHTMIRIKNPTRSLEFYQ 201

Query: 640 KALGMKLLRKXDVPQYKYT 696
             LGMKLLR  +    K+T
Sbjct: 202 NVLGMKLLRTSEHESAKFT 220



 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 16/151 (10%)
 Frame = +1

Query: 163 EWPKQDK-KRMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTN 339
           E+PK     +  H + R+ +  ++++ Y    GMKLLR  +    K+T  FLG+G   T+
Sbjct: 173 EYPKGSVGNKFNHTMIRIKNPTRSLEFYQNVLGMKLLRTSEHESAKFTLYFLGYGVPKTD 232

Query: 340 FA------LELTYNYGVDK-----YDIG----AGFGHFAIANEDVYKLSETIKSSDCCKI 474
                   LELT+N+G +      Y  G     G+GH  I+ +D   L + I+     KI
Sbjct: 233 SVFSCESVLELTHNWGTENDPNFHYHNGNSEPQGYGHICISCDDAGALCKEIEVKYGDKI 292

Query: 475 TREPGPVKGGSTVIAFAQDPDGYLFELIQRG 567
              P   +G    IAF +DPDGY  E++  G
Sbjct: 293 QWSPKFNQGRMKNIAFLKDPDGYSIEVVPHG 323

>LGUL_SCHPO (Q09751) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 302

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 69/198 (34%), Positives = 100/198 (50%), Gaps = 28/198 (14%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGF-GPEDTNFA------ 345
           ++ H + RV DLDK++K YTE FGMKL+ +    E +++ +FL F GP   N        
Sbjct: 11  KLNHTMIRVKDLDKSLKFYTEVFGMKLIDQWVFEENEFSLSFLAFDGPGALNHGVERSKR 70

Query: 346 ---LELTYNYGVDK-----YDIG-----AGFGHFAIANEDVYKLSETIKSSDCCKITREP 486
              LELTYN+G +K     Y  G      GFGH     +++      ++S     ++ + 
Sbjct: 71  EGILELTYNFGTEKKEGPVYINGNTEPKRGFGHICFTVDNIESACAYLESKG---VSFKK 127

Query: 487 GPVKGGSTVIAFAQDPDGYLFELIQRGPTPEPLCQV--------MLRVGDLDRAIMFYEK 642
               G    IAFA DPD Y  EL+ +  T +P   +        M+RV D + +I FYEK
Sbjct: 128 KLSDGKMKHIAFALDPDNYWIELVSQSET-KPKANISNFRFNHTMVRVKDPEPSIAFYEK 186

Query: 643 ALGMKLLRKXDVPQYKYT 696
            LGMK++ K D P  K+T
Sbjct: 187 -LGMKVIDKADHPNGKFT 203



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 48/145 (33%), Positives = 69/145 (47%), Gaps = 19/145 (13%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPE----DTNFALEL 354
           R  H + RV D + +I  Y E  GMK++ K D P  K+TN FL +  +    D    LEL
Sbjct: 166 RFNHTMVRVKDPEPSIAFY-EKLGMKVIDKADHPNGKFTNYFLAYPSDLPRHDREGLLEL 224

Query: 355 TYNYGVDK-----YDIG-----AGFGHFAIANEDVYKLSETIKSSDCCKITREPGPVK-- 498
           T+N+G +K     Y  G      G+GH  I+ +++        ++ C K   E  P K  
Sbjct: 225 THNWGTEKESGPVYHNGNDGDEKGYGHVCISVDNI--------NAACSKFEAEGLPFKKK 276

Query: 499 ---GGSTVIAFAQDPDGYLFELIQR 564
              G    IAF  DPD Y  E+I++
Sbjct: 277 LTDGRMKDIAFLLDPDNYWVEVIEQ 301

>YQ5A_CAEEL (Q09253) Hypothetical protein C16C10.10|
          Length = 281

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 47/174 (27%), Positives = 91/174 (52%), Gaps = 13/174 (7%)
 Frame = +1

Query: 187 RMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEE-----------KYTNAFLGFGPED 333
           R LH V++V +  KTI  +T    MK+LR  +  +            +++   +G+G ED
Sbjct: 4   RALHYVFKVANRAKTIDFFTNVLNMKVLRHEEFEKGCEATCNGPYNGRWSKTMIGYGSED 63

Query: 334 TNFALELTYNYGVDKYDIGAGFGHFAIANEDVYKLSETI--KSSDCCKITREPGPVKGGS 507
            +F LE+TYNY + KY++G  +    I ++ +++  E I  + S C ++           
Sbjct: 64  EHFVLEITYNYPIHKYELGNDYRAIVIDSDQLFEKVEKINHRKSGCGRLA---------- 113

Query: 508 TVIAFAQDPDGYLFELIQRGPTPEPLCQVMLRVGDLDRAIMFYEKALGMKLLRK 669
                 +DPDG+ F++ +   +P+ L +V + VGDL+++  ++ + LGM ++ +
Sbjct: 114 -----VKDPDGHEFKIGKADQSPKVL-RVQVNVGDLEKSKKYWNETLGMPIVEE 161

>LGUL_LYCES (Q42891) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 185

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 46/145 (31%), Positives = 71/145 (48%), Gaps = 27/145 (18%)
 Frame = +1

Query: 202 VYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFA------------ 345
           ++R+ D   +++ Y++  GM LL++ D PE K++  F+G+  EDT  A            
Sbjct: 32  MFRIKDPKVSLEFYSKVLGMSLLKRLDFPEMKFSLYFMGY--EDTASAPSDPVERTAWTF 89

Query: 346 -----LELTYNYGVDK------YDIG----AGFGHFAIANEDVYKLSETIKSSDCCKITR 480
                LELT+N+G +       Y  G     GFGH  +  +DVYK  E  +S     + +
Sbjct: 90  SQKSTLELTHNWGTESDPNFTGYHNGNSEPRGFGHIGVTVDDVYKACERFESLGVEFVKK 149

Query: 481 EPGPVKGGSTVIAFAQDPDGYLFEL 555
              P+ G    IAF +DPDGY  E+
Sbjct: 150 ---PLDGKMKGIAFIKDPDGYWIEI 171



 Score = 36.6 bits (83), Expect = 0.075
 Identities = 16/38 (42%), Positives = 24/38 (63%)
 Frame = +1

Query: 583 LCQVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           L Q M R+ D   ++ FY K LGM LL++ D P+ K++
Sbjct: 28  LQQTMFRIKDPKVSLEFYSKVLGMSLLKRLDFPEMKFS 65

>LGUL_CICAR (O49818) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 186

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 48/153 (31%), Positives = 72/153 (47%), Gaps = 28/153 (18%)
 Frame = +1

Query: 190 MLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFA-------- 345
           M   ++R+ D   ++  Y+   GM LL++ D PE K++  F+G+  EDT  A        
Sbjct: 29  MQQTMFRIKDPKVSLDFYSRVLGMSLLKRLDFPEMKFSLYFMGY--EDTTEAPSNPVDRT 86

Query: 346 ---------LELTYNYGVDK------YDIG----AGFGHFAIANEDVYKLSETIKSSDCC 468
                    +ELT+N+G +       Y  G     GFGH  I  +D YK  E  ++    
Sbjct: 87  VWTFAQKATIELTHNWGTESDPEFKGYHNGNSDPRGFGHIGITVDDTYKACERFQNLGVE 146

Query: 469 KITR-EPGPVKGGSTVIAFAQDPDGYLFELIQR 564
            + + + G +KG    IAF +DPDGY  EL  R
Sbjct: 147 FVKKPDDGKMKG----IAFIKDPDGYWIELFDR 175



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 14/36 (38%), Positives = 23/36 (63%)
 Frame = +1

Query: 589 QVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           Q M R+ D   ++ FY + LGM LL++ D P+ K++
Sbjct: 31  QTMFRIKDPKVSLDFYSRVLGMSLLKRLDFPEMKFS 66

>LGUL_PSEPU (P16635) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 172

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 48/151 (31%), Positives = 70/151 (46%), Gaps = 24/151 (15%)
 Frame = +1

Query: 196 HAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFG-----PEDTNF------ 342
           H + RV D++K++  YT   G KL+ KRD  E K++  FL        P D +       
Sbjct: 26  HTMLRVKDIEKSLDFYTRVLGFKLVDKRDFVEAKFSLYFLALVDPATIPADDDARHQWMK 85

Query: 343 ----ALELTYNYGVDK-----YDIG----AGFGHFAIANEDVYKLSETIKSSDCCKITRE 483
                LELT+N+G ++     Y  G     GFGH  ++  DV    E     +  ++  +
Sbjct: 86  SIPGVLELTHNHGTERDADFAYHHGNTDPRGFGHICVSVPDVVAACERF---EALQVPFQ 142

Query: 484 PGPVKGGSTVIAFAQDPDGYLFELIQRGPTP 576
                G    +AF +DPDGY  E+IQ  PTP
Sbjct: 143 KRLSDGRMNHLAFIKDPDGYWVEVIQ--PTP 171



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 14/34 (41%), Positives = 24/34 (70%)
 Frame = +1

Query: 595 MLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           MLRV D+++++ FY + LG KL+ K D  + K++
Sbjct: 28  MLRVKDIEKSLDFYTRVLGFKLVDKRDFVEAKFS 61

>LGUL_RAT (Q6P7Q4) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 183

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 48/145 (33%), Positives = 68/145 (46%), Gaps = 28/145 (19%)
 Frame = +1

Query: 208 RVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTN---------------- 339
           R+ D  K++  YT   G+ LL+K D P  K++  FL +  ED N                
Sbjct: 37  RIKDPKKSLDFYTRVLGLTLLQKLDFPSMKFSLYFLAY--EDKNDIPKDKTERTAWAFSR 94

Query: 340 -FALELTYNYGVD-----KYDIG----AGFGHFAIANEDVYKLSETIKSSDCCKITREP- 486
              LELT+N+G +      Y  G     GFGH  IA  DVY+  +  +     K  ++P 
Sbjct: 95  KATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYEACKRFEELG-VKFVKKPD 153

Query: 487 -GPVKGGSTVIAFAQDPDGYLFELI 558
            G +KG    +AF QDPDGY  E++
Sbjct: 154 DGKMKG----LAFVQDPDGYWIEIL 174



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = +1

Query: 481 EPGPVKGGST---VIAFAQDPDGYLFELIQRGPTPEPLCQVMLRVGDLDRAIMFYEKALG 651
           EP P   G T    ++   DPD    + +        L Q MLR+ D  +++ FY + LG
Sbjct: 2   EPQPASSGLTDEAALSCCSDPDPSTKDFL--------LQQTMLRIKDPKKSLDFYTRVLG 53

Query: 652 MKLLRKXDVPQYKYT 696
           + LL+K D P  K++
Sbjct: 54  LTLLQKLDFPSMKFS 68

>LGUL_MOUSE (Q9CPU0) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 183

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 48/145 (33%), Positives = 67/145 (46%), Gaps = 28/145 (19%)
 Frame = +1

Query: 208 RVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTN---------------- 339
           R+ D  K++  YT   G+ LL+K D P  K++  FL +  ED N                
Sbjct: 37  RIKDPKKSLDFYTRVLGLTLLQKLDFPAMKFSLYFLAY--EDKNDIPKDKSEKTAWTFSR 94

Query: 340 -FALELTYNYGVD-----KYDIG----AGFGHFAIANEDVYKLSETIKSSDCCKITREP- 486
              LELT+N+G +      Y  G     GFGH  IA  DVY   +  +     K  ++P 
Sbjct: 95  KATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELG-VKFVKKPD 153

Query: 487 -GPVKGGSTVIAFAQDPDGYLFELI 558
            G +KG    +AF QDPDGY  E++
Sbjct: 154 DGKMKG----LAFIQDPDGYWIEIL 174



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
 Frame = +1

Query: 481 EPGPVKGG---STVIAFAQDPDGYLFELIQRGPTPEPLCQVMLRVGDLDRAIMFYEKALG 651
           EP P   G    T  +   DPD    + +        L Q MLR+ D  +++ FY + LG
Sbjct: 2   EPQPASSGLTDETAFSCCSDPDPSTKDFL--------LQQTMLRIKDPKKSLDFYTRVLG 53

Query: 652 MKLLRKXDVPQYKYT 696
           + LL+K D P  K++
Sbjct: 54  LTLLQKLDFPAMKFS 68

>LGUL_HUMAN (Q04760) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 183

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 49/145 (33%), Positives = 67/145 (46%), Gaps = 28/145 (19%)
 Frame = +1

Query: 208 RVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTN---------------- 339
           RV D  K++  YT   GM L++K D P  K++  FL +  ED N                
Sbjct: 37  RVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAY--EDKNDIPKEKDEKIAWALSR 94

Query: 340 -FALELTYNYGVD-----KYDIG----AGFGHFAIANEDVYKLSETIKSSDCCKITREP- 486
              LELT+N+G +      Y  G     GFGH  IA  DVY   +  +     K  ++P 
Sbjct: 95  KATLELTHNWGTEDDATQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELG-VKFVKKPD 153

Query: 487 -GPVKGGSTVIAFAQDPDGYLFELI 558
            G +KG    +AF QDPDGY  E++
Sbjct: 154 DGKMKG----LAFIQDPDGYWIEIL 174



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = +1

Query: 481 EPGPVKGGST---VIAFAQDPDGYLFELIQRGPTPEPLCQVMLRVGDLDRAIMFYEKALG 651
           EP P  GG T    ++   D D    + +        L Q MLRV D  +++ FY + LG
Sbjct: 2   EPQPPSGGLTDEAALSCCSDADPSTKDFL--------LQQTMLRVKDPKKSLDFYTRVLG 53

Query: 652 MKLLRKXDVPQYKYT 696
           M L++K D P  K++
Sbjct: 54  MTLIQKCDFPIMKFS 68

>LGUL_BRAJU (O04885) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 185

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 45/149 (30%), Positives = 68/149 (45%), Gaps = 27/149 (18%)
 Frame = +1

Query: 190 MLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFA-------- 345
           M   ++RV D   ++  Y+   GM LL++ D  E K++  FLG+  EDT+ A        
Sbjct: 28  MQQTMFRVKDPKASLDFYSRVLGMSLLKRLDFSEMKFSLYFLGY--EDTSTAPTDPTERT 85

Query: 346 ---------LELTYNYGVDK------YDIG----AGFGHFAIANEDVYKLSETIKSSDCC 468
                    +ELT+N+G +       Y  G     GFGH  +  +DV+K  E  +     
Sbjct: 86  VWTFGRPATIELTHNWGTESDPEFKGYHNGNSEPRGFGHIGVTVDDVHKACERFEQLGVE 145

Query: 469 KITREPGPVKGGSTVIAFAQDPDGYLFEL 555
            + +   P  G    IAF +DPDGY  E+
Sbjct: 146 FVKK---PHDGKMKNIAFIKDPDGYWIEI 171



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 14/36 (38%), Positives = 22/36 (61%)
 Frame = +1

Query: 589 QVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           Q M RV D   ++ FY + LGM LL++ D  + K++
Sbjct: 30  QTMFRVKDPKASLDFYSRVLGMSLLKRLDFSEMKFS 65

>LGUL_MACFA (Q4R5F2) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 183

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 48/145 (33%), Positives = 67/145 (46%), Gaps = 28/145 (19%)
 Frame = +1

Query: 208 RVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTN---------------- 339
           RV D  K++  YT   GM L++K D P  K++  FL +  ED N                
Sbjct: 37  RVKDPKKSLDFYTRVLGMTLIQKCDFPAMKFSLYFLAY--EDKNDIPKDKEEKIAWALSR 94

Query: 340 -FALELTYNYGVD-----KYDIG----AGFGHFAIANEDVYKLSETIKSSDCCKITREP- 486
              LELT+N+G +      Y  G     GFGH  IA  DV+   +  +     K  ++P 
Sbjct: 95  KATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVHSACKRFEELG-VKFVKKPD 153

Query: 487 -GPVKGGSTVIAFAQDPDGYLFELI 558
            G +KG    +AF QDPDGY  E++
Sbjct: 154 DGKMKG----LAFIQDPDGYWIEIL 174



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
 Frame = +1

Query: 481 EPGPVKGGST---VIAFAQDPDGYLFELIQRGPTPEPLCQVMLRVGDLDRAIMFYEKALG 651
           EP P  GG T    ++   D D    + +        L Q MLRV D  +++ FY + LG
Sbjct: 2   EPQPPSGGLTDEAALSCCSDADPSTKDFL--------LQQTMLRVKDPKKSLDFYTRVLG 53

Query: 652 MKLLRKXDVPQYKYT 696
           M L++K D P  K++
Sbjct: 54  MTLIQKCDFPAMKFS 68

>LGUL_ARATH (Q8H0V3) Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase)|
           (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde
           mutase) (S-D-lactoylglutathione methylglyoxal lyase)
          Length = 185

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 44/149 (29%), Positives = 68/149 (45%), Gaps = 27/149 (18%)
 Frame = +1

Query: 190 MLHAVYRVGDLDKTIKCYTECFGMKLLRKRDVPEEKYTNAFLGFGPEDTNFA-------- 345
           M   ++R+ D   ++  Y+   GM LL++ D  E K++  FLG+  EDT  A        
Sbjct: 28  MQQTMFRIKDPKASLDFYSRVLGMSLLKRLDFSEMKFSLYFLGY--EDTTTAPTDPTERT 85

Query: 346 ---------LELTYNYGVDK------YDIG----AGFGHFAIANEDVYKLSETIKSSDCC 468
                    +ELT+N+G +       Y  G     GFGH  +  +DV+K  E  +     
Sbjct: 86  VWTFGQPATIELTHNWGTESDPEFKGYHNGNSEPRGFGHIGVTVDDVHKACERFEELGV- 144

Query: 469 KITREPGPVKGGSTVIAFAQDPDGYLFEL 555
           +  ++P    G    IAF +DPDGY  E+
Sbjct: 145 EFAKKPND--GKMKNIAFIKDPDGYWIEI 171



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 13/36 (36%), Positives = 22/36 (61%)
 Frame = +1

Query: 589 QVMLRVGDLDRAIMFYEKALGMKLLRKXDVPQYKYT 696
           Q M R+ D   ++ FY + LGM LL++ D  + K++
Sbjct: 30  QTMFRIKDPKASLDFYSRVLGMSLLKRLDFSEMKFS 65

>Y3371_MYCTU (O50400) Hypothetical UPF0089 protein Rv3371/MT3481|
          Length = 446

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 16/40 (40%), Positives = 23/40 (57%)
 Frame = -2

Query: 642 LLVEHDSPIKVTNTKHNLTERLRRRTPLDKLKQVTIWVLC 523
           L VE+D P++   T HN +++  RR P D L   T  +LC
Sbjct: 277 LPVEYDDPVRRLRTVHNRSQQSGRRQP-DSLSDYTPLMLC 315

>PYR1_DROME (P05990) CAD protein (Protein rudimentary) [Includes:|
            Glutamine-dependent carbamoyl-phosphate synthase (EC
            6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2);
            Dihydroorotase (EC 3.5.2.3)]
          Length = 2224

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 21/90 (23%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
 Frame = +1

Query: 208  RVGDLDKTIKCYTECFGMKLLRKRDV----PEEKYTNAFLGFGPEDTNFALELTYNYGVD 375
            R G  DK I  Y +   + +  +R      P  K  +   G  P  TN+   L + Y   
Sbjct: 882  RFGFSDKQIAKYIKSTELAVRHQRQEFGIRPHVKQIDTVAGEWPASTNY---LYHTYNGS 938

Query: 376  KYDIGAGFGHFAIANEDVYKLSETIKSSDC 465
            ++D+    GH  +    VY++  +++   C
Sbjct: 939  EHDVDFPGGHTIVVGSGVYRIGSSVEFDWC 968

>Y3087_MYCTU (O53304) Hypothetical UPF0089 protein Rv3087/MT3172|
          Length = 472

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
 Frame = +2

Query: 125 PVAKLESPPRPCWNGLSRTKRGCCMLFTVWEI--LTKPLSVTQNALG*SC 268
           P     +PP P   GLSR++R  C  F + E+  ++K L VT N +  +C
Sbjct: 222 PTFDRSAPPGPFQRGLSRSRRFSCESFPLAEVREVSKTLGVTINDVFLAC 271

>ICAL_RABIT (P08855) Calpastatin (Calpain inhibitor) [Contains: Erythrocyte|
           calpastatin]
          Length = 718

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
 Frame = +1

Query: 19  GSLPDRISGVSIPKSISFVLSSACFLYAPVTTGMATGSEAGKSAEAVLE----------W 168
           G  PD ++ +    +I   LSS     +PV +G   G EA KSA  VLE           
Sbjct: 217 GPPPDSVTPLGPDDAID-ALSSDFTCSSPVASGKEAGKEAAKSAGEVLEAESAKVMRAAA 275

Query: 169 PKQDKKR 189
           P Q+KKR
Sbjct: 276 PPQEKKR 282

>MCEE_MOUSE (Q9D1I5) Methylmalonyl-CoA epimerase, mitochondrial precursor (EC|
           5.1.99.1) (DL-methylmalonyl-CoA racemase)
          Length = 178

 Score = 30.4 bits (67), Expect = 5.4
 Identities = 40/170 (23%), Positives = 61/170 (35%), Gaps = 9/170 (5%)
 Frame = +1

Query: 79  SSACFLYAPVTTGMATGSEAGKSAEAVLEW-PKQDKKRMLHAVYRVGDLDKTIKCYTECF 255
           + A  L++ V T +A G           E  P     R+ H    V DL+K    Y +  
Sbjct: 12  AGATGLFSRVQTSVAIGRSFSTPQSQFQESSPVWKLGRLNHVAVAVPDLEKASSFYRDVL 71

Query: 256 GMKLLRKRDVPEEKYTNAFLGFGPEDTNFALELTYNYGVDKYDIG-------AGFGHFAI 414
           G ++     +PE   +  F+  G    N  +EL +  G D    G        G  H  I
Sbjct: 72  GAQVSEVVPLPEHGVSVVFVNLG----NTKMELLHPLGSDSPITGFLQKNKAGGMHHVCI 127

Query: 415 ANEDVYKLSETIKSSDCCKITREPGPVKGGSTVI-AFAQDPDGYLFELIQ 561
             +++      +K      ++ E      G  VI    +D  G L EL Q
Sbjct: 128 EVDNISAAVMDLKKKKIRSLSDEAKIGAHGKPVIFLHPKDCGGVLVELEQ 177

>MCEE_HUMAN (Q96PE7) Methylmalonyl-CoA epimerase, mitochondrial precursor (EC|
           5.1.99.1) (DL-methylmalonyl-CoA racemase)
          Length = 176

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 38/164 (23%), Positives = 58/164 (35%), Gaps = 8/164 (4%)
 Frame = +1

Query: 94  LYAPVTTGMATGSEAGKSAEAVLEWPKQDKKRMLHAVYRVGDLDKTIKCYTECFGMKLLR 273
           L AP+ T  A+ +           W   +  R+ H    V DL+K    Y    G ++  
Sbjct: 19  LQAPIPTVRASSTSQPLDQVTGSVW---NLGRLNHVAIAVPDLEKAAAFYKNILGAQVSE 75

Query: 274 KRDVPEEKYTNAFLGFGPEDTNFALELTYNYGVDKYDIG-------AGFGHFAIANEDVY 432
              +PE   +  F+  G    N  +EL +  G D    G        G  H  I  +++ 
Sbjct: 76  AVPLPEHGVSVVFVNLG----NTKMELLHPLGRDSPIAGFLQKNKAGGMHHICIEVDNIN 131

Query: 433 KLSETIKSSDCCKITREPGPVKGGSTVI-AFAQDPDGYLFELIQ 561
                +K      ++ E      G  VI    +D  G L EL Q
Sbjct: 132 AAVMDLKKKKIRSLSEEVKIGAHGKPVIFLHPKDCGGVLVELEQ 175

>RRP44_HUMAN (Q9Y2L1) Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal|
           RNA-processing protein 44) (DIS3 protein homolog)
          Length = 958

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 21/75 (28%), Positives = 36/75 (48%)
 Frame = +1

Query: 106 VTTGMATGSEAGKSAEAVLEWPKQDKKRMLHAVYRVGDLDKTIKCYTECFGMKLLRKRDV 285
           + T  A+  E  +   A+  WP+  +    H V  +GD+ +  +  TE     LL + DV
Sbjct: 385 IETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEK-ETETEV----LLLEHDV 439

Query: 286 PEEKYTNAFLGFGPE 330
           P + ++ A L F P+
Sbjct: 440 PHQPFSQAVLSFLPK 454

>RPOC2_PSEAK (Q3ZJ90) DNA-directed RNA polymerase beta'' chain (EC 2.7.7.6) (PEP)|
            (Plastid-encoded RNA polymerase beta'' subunit) (RNA
            polymerase beta'' subunit)
          Length = 3462

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 15/49 (30%), Positives = 26/49 (53%)
 Frame = -2

Query: 279  SFPQQLHPKAFCVTLNGFVKISHTVNSMQHPLFVLLRPFQHGLGGLSSF 133
            SFP+++H K   +T    +  S   +S++   F  ++  Q+G G LS F
Sbjct: 2238 SFPKKIHRKTLFITHPSIIWKSRFESSLKSLTFFKMKAKQNGTGSLSFF 2286

>DAPF_XYLFA (Q9PD98) Diaminopimelate epimerase (EC 5.1.1.7) (DAP epimerase)|
          Length = 284

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 29/105 (27%), Positives = 45/105 (42%)
 Frame = -2

Query: 342 KISILRSKPKKRIGVLLFWDISFPQQLHPKAFCVTLNGFVKISHTVNSMQHPLFVLLRPF 163
           ++ ++   P +RIG LL   ++FP+ ++         GFV++         P  V LR +
Sbjct: 173 EVDLIDVAPVERIGSLLQQHVAFPESVNV--------GFVQVI-------DPGLVRLRVY 217

Query: 162 QHGLGGLSSFATGSHPCCHRRVKEASGREDEGDGFGDAHPGNTIR 28
           + G G   + A GS  C    V    GR   G       PG T+R
Sbjct: 218 ERGAG--ETLACGSGACAAAVVLMQRGR--VGRDVRVVLPGGTLR 258

>IF2_BLOFL (Q7VQM3) Translation initiation factor IF-2|
          Length = 897

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 37/124 (29%), Positives = 60/124 (48%), Gaps = 10/124 (8%)
 Frame = -2

Query: 633 EHDSPIKVTNTKHNLTERLR--RRTPLDKLKQVTIWVLCKGNHSGPSL----DRTRFTSD 472
           EHD   K+ N + NLT+RLR  R   L KL +       K N+S   +    D+      
Sbjct: 225 EHDKQ-KLENVRKNLTDRLRSTRTRNLSKLVKQN-----KHNNSKVCMIYESDKDEKLYV 278

Query: 471 LTTIR*F-NCLRQLVHILICDGKMSKARSNVVLVNTIIVSQLKCKISILRS---KPKKRI 304
           L + R + N  +Q + +   +  M K   +VV+  TI V++L  K+SI  S   K   ++
Sbjct: 279 LPSSRVYKNKRKQSILVQSFNKPMQKTVRDVVIGETISVAELSNKMSIKSSSMIKMMMKL 338

Query: 303 GVLL 292
           G+++
Sbjct: 339 GLMV 342

>YFAZ_ECOLI (P76471) Hypothetical protein yfaZ precursor|
          Length = 180

 Score = 29.6 bits (65), Expect = 9.1
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
 Frame = +1

Query: 292 EKYTNAFLGFGPEDTNFALELTYNYGVDKYDI-GAGFG 402
           ++YTN  +GFG E T  AL   + +  D  D+ G G G
Sbjct: 30  KEYTNIGVGFGTETTGLALSGNWTHNDDDGDVAGVGLG 67


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,284,276
Number of Sequences: 219361
Number of extensions: 2137314
Number of successful extensions: 6426
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 6086
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6382
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 6912958834
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)