ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags21e13 |
|---|---|
| Clone Library Name | barley_pub |
>HXK1_SPIOL (Q9SEK3) Hexokinase-1 (EC 2.7.1.1)| Length = 498 Score = 211 bits (537), Expect = 1e-54 Identities = 105/172 (61%), Positives = 130/172 (75%) Frame = +1 Query: 94 LVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYG 273 ++ +L + C TP+ LR VA AM EM AGL EG S++KML+SYVD LPTG E GLFY Sbjct: 40 ILKELDDNCGTPLGKLRQVADAMTVEMHAGLASEGASKLKMLISYVDNLPTGDEHGLFYA 99 Query: 274 LDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEE 453 LDLGGTNFRVL+V+LGG +K V+ +E EV+IPP LM G+S +LF +IA LAKFV E Sbjct: 100 LDLGGTNFRVLRVKLGGKEKRVVEQEFDEVSIPPELMVGTSEQLFDYIAEALAKFVATES 159 Query: 454 KGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 +G K+ ELGFTFSFPV+Q S+ASGTL++WTK F+IED VG+DVVAEL Sbjct: 160 EGLHPEPNKQRELGFTFSFPVKQTSIASGTLIRWTKGFNIEDTVGEDVVAEL 211
>HXK2_SOLTU (Q9SQ76) Hexokinase-2 (EC 2.7.1.1)| Length = 496 Score = 209 bits (532), Expect = 5e-54 Identities = 106/177 (59%), Positives = 131/177 (74%) Frame = +1 Query: 79 AMAEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGRED 258 A A ++ + EKC TP L+ VA AM EM AGL EGGS++KML+SYVD LPTG E Sbjct: 35 ARARAILKEFEEKCATPDGKLKQVADAMTVEMHAGLASEGGSKLKMLISYVDNLPTGDEG 94 Query: 259 GLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKF 438 G+FY LDLGGTNFRVL+VQLGG D +I +E E +IPP+LM G+S LF +IA+ELAKF Sbjct: 95 GVFYALDLGGTNFRVLRVQLGGKDGGIIHQEFAEASIPPNLMVGTSEALFDYIAAELAKF 154 Query: 439 VTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 V +E + G++ ELGFTFSFP+ Q S+ SGTL++WTK FSI+D VGKDVVAEL Sbjct: 155 VAEEGEEFHPPPGRQRELGFTFSFPIMQTSINSGTLIRWTKGFSIDDTVGKDVVAEL 211
>HXK1_ARATH (Q42525) Hexokinase-1 (EC 2.7.1.1)| Length = 496 Score = 208 bits (530), Expect = 9e-54 Identities = 104/166 (62%), Positives = 127/166 (76%) Frame = +1 Query: 112 EKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGT 291 E C TP+S LR VA AM EM AGL +GGS++KML+SYVD LP+G E GLFY LDLGGT Sbjct: 46 EDCATPISKLRQVADAMTVEMHAGLASDGGSKLKMLISYVDNLPSGDEKGLFYALDLGGT 105 Query: 292 NFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLS 471 NFRV++V LGG + V+ +E EV+IPPHLM+G S ELF FIA LAKFV E + L Sbjct: 106 NFRVMRVLLGGKQERVVKQEFEEVSIPPHLMTGGSDELFNFIAEALAKFVATECEDFHLP 165 Query: 472 NGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 G++ ELGFTFSFPV+Q S++SG+L+KWTK FSIE+AVG+DVV L Sbjct: 166 EGRQRELGFTFSFPVKQTSLSSGSLIKWTKGFSIEEAVGQDVVGAL 211
>HXK1_TOBAC (Q9SEK2) Hexokinase-1 (EC 2.7.1.1)| Length = 497 Score = 206 bits (525), Expect = 3e-53 Identities = 104/177 (58%), Positives = 132/177 (74%) Frame = +1 Query: 79 AMAEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGRED 258 A A ++ + EKC TP + L+ VA AM EM AGL EGGS++KML++YVD LPTG E Sbjct: 35 ARAMAILREFEEKCGTPDAKLKQVADAMTVEMHAGLASEGGSKLKMLITYVDNLPTGDEA 94 Query: 259 GLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKF 438 G+FY LDLGGTNFRVL+VQLGG D ++ +E E +IPP+LM G+S LF +IA+ELAKF Sbjct: 95 GVFYALDLGGTNFRVLRVQLGGKDGGIVHQEFAEASIPPNLMVGTSEALFDYIAAELAKF 154 Query: 439 VTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 V +E + GK+ ELGFTFSFPV Q S+ SGT+++WTK FSI+DAVG+DVV EL Sbjct: 155 VNEEGEKFQQPPGKQRELGFTFSFPVMQTSINSGTIMRWTKGFSIDDAVGQDVVGEL 211
>HXK2_ARATH (P93834) Hexokinase-2 (EC 2.7.1.1)| Length = 502 Score = 203 bits (517), Expect = 3e-52 Identities = 102/173 (58%), Positives = 125/173 (72%) Frame = +1 Query: 91 QLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFY 270 +++ E C TP++ LR VA AM EM AGL EGGS++KML+SYVD LP+G E G FY Sbjct: 39 EILKAFEEDCATPIAKLRQVADAMTVEMHAGLASEGGSKLKMLISYVDNLPSGDETGFFY 98 Query: 271 GLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDE 450 LDLGGTNFRV++V LGG V+ RE +E +IPPHLM+G S ELF FI LAKFV E Sbjct: 99 ALDLGGTNFRVMRVLLGGKHDRVVKREFKEESIPPHLMTGKSHELFDFIVDVLAKFVATE 158 Query: 451 EKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 + L G++ ELGFTFSFPV+Q S++SGTL+ WTK FSI+D V KDVV EL Sbjct: 159 GEDFHLPPGRQRELGFTFSFPVKQLSLSSGTLINWTKGFSIDDTVDKDVVGEL 211
>HXK1_SOLTU (O64390) Hexokinase-1 (EC 2.7.1.1)| Length = 498 Score = 152 bits (385), Expect = 6e-37 Identities = 88/177 (49%), Positives = 113/177 (63%), Gaps = 2/177 (1%) Frame = +1 Query: 85 AEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKML--LSYVDKLPTGRED 258 A ++ + EKC T + L+ VA AM EM AGL EGG + L +S + +L + Sbjct: 37 AMAILREFEEKCKTQDAKLKQVADAMTVEMHAGLASEGGQSSRCLSPMSIISQLVM--KL 94 Query: 259 GLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKF 438 G+FY LDLGGTNFRVL+VQLGG D +I +E E +IPP LM G+S LF +IA+ELAKF Sbjct: 95 GVFYALDLGGTNFRVLRVQLGGKDGGIIHQEFAEASIPPSLMVGTSDALFDYIAAELAKF 154 Query: 439 VTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 V EE+ GK+ ELGF P SGT+++WTK FSI+DAVG+DVV EL Sbjct: 155 VAAEEEKFHQPPGKQRELGFHLLIPSNADFNNSGTIMRWTKGFSIDDAVGQDVVGEL 211
>HXK_KLULA (P33284) Hexokinase (EC 2.7.1.1)| Length = 484 Score = 119 bits (298), Expect = 7e-27 Identities = 75/190 (39%), Positives = 104/190 (54%) Frame = +1 Query: 43 P*SAGRASGAPVAMAEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLL 222 P G + P + EQ + L +R + E+ GL K+GG+ + M+ Sbjct: 9 PARKGSMADVPANLMEQ-IHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGN-IPMIP 66 Query: 223 SYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSE 402 +V + PTG+E G F LDLGGTN RV+ V+LGGN H + +P HL +G+S + Sbjct: 67 GWVVEYPTGKETGDFLALDLGGTNLRVVLVKLGGN--HDFDTTQNKYRLPDHLRTGTSEQ 124 Query: 403 LFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDA 582 L++FIA L +FV DE +S + L LGFTFS+P Q+ + SG L +WTK F IE Sbjct: 125 LWSFIAKCLKEFV-DEWYPDGVS--EPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGV 181 Query: 583 VGKDVVAELQ 612 G DVV LQ Sbjct: 182 EGHDVVPMLQ 191
>HXK_SCHMA (Q26609) Hexokinase (EC 2.7.1.1)| Length = 451 Score = 118 bits (295), Expect = 2e-26 Identities = 75/174 (43%), Positives = 94/174 (54%), Gaps = 2/174 (1%) Frame = +1 Query: 97 VADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGG--SRVKMLLSYVDKLPTGREDGLFY 270 V ++ + D V ++ M + M GL+K S +KM SYV K P G E G F Sbjct: 12 VVEILKPFDLSVVDYEEICDRMGESMRLGLQKSTNEKSSIKMFPSYVTKTPNGTETGNFL 71 Query: 271 GLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDE 450 LDLGGTN+RVL V L G K +E R IP MSGS +ELF +IA LA F+ E Sbjct: 72 ALDLGGTNYRVLSVTLEGKGKSPRIQE-RTYCIPAEKMSGSGTELFKYIAETLADFL--E 128 Query: 451 EKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 G KK +LGFTFSFP Q+ + TLV+WTK FS + G +V LQ Sbjct: 129 NNG---MKDKKFDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQ 179
>HXK1_MOUSE (P17710) Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I)| (Hexokinase, tumor isozyme) Length = 974 Score = 117 bits (292), Expect = 3e-26 Identities = 76/201 (37%), Positives = 106/201 (52%), Gaps = 8/201 (3%) Frame = +1 Query: 34 VISP*SAGRASGAPVAMAEQLVADLREKCDT------PVSLLRDVAAAMADEMCAGLEKE 195 ++S +G+ + A+A +L R+ +T L +V + EM GL KE Sbjct: 499 LLSESGSGKGAAMVTAVAYRLAEQHRQIEETLSHFRLSKQALMEVKKKLRSEMEMGLRKE 558 Query: 196 GGSR--VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAI 369 SR VKML SYV +P G E G F LDLGGTNFRVL V++ K + ++ +I Sbjct: 559 TNSRATVKMLPSYVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSI 618 Query: 370 PPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLV 549 P +M G+ ELF I S ++ F+ + G G ++ LGFTFSFP +Q S+ G L+ Sbjct: 619 PLEIMQGTGDELFDHIVSCISDFL--DYMGI---KGPRMPLGFTFSFPCKQTSLDCGILI 673 Query: 550 KWTKAFSIEDAVGKDVVAELQ 612 WTK F D VG DV L+ Sbjct: 674 TWTKGFKATDCVGHDVATLLR 694 Score = 101 bits (252), Expect = 2e-21 Identities = 59/157 (37%), Positives = 83/157 (52%), Gaps = 2/157 (1%) Frame = +1 Query: 136 LLRDVAAAMADEMCAGLEKEGG--SRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLK 309 +L D+ EM GL ++ + VKML ++V +P G E G F LDLGG++FR+L+ Sbjct: 91 ILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILR 150 Query: 310 VQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLE 489 VQ+ +S ES P +++ GS S+LF +A L F+ + KKL Sbjct: 151 VQVNHEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRK-----IKDKKLP 205 Query: 490 LGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVV 600 +GFTFSFP RQ + L+ WTK F G DVV Sbjct: 206 VGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVV 242
>HXK1_HUMAN (P19367) Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Brain| form hexokinase) Length = 917 Score = 115 bits (288), Expect = 1e-25 Identities = 75/201 (37%), Positives = 109/201 (54%), Gaps = 8/201 (3%) Frame = +1 Query: 34 VISP*SAGRASGAPVAMAEQLVADLREKCDTPV------SLLRDVAAAMADEMCAGLEKE 195 ++S +G+ + A+A +L R+ +T +L +V M EM GL K+ Sbjct: 443 LLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQ 502 Query: 196 --GGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAI 369 + VKML S+V + P G E+G F LDLGGTNFRVL V++ K + ++ AI Sbjct: 503 THNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAI 562 Query: 370 PPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLV 549 P +M G+ ELF I S ++ F+ + G G ++ LGFTFSFP +Q S+ +G L+ Sbjct: 563 PIEIMQGTGEELFDHIVSCISDFL--DYMGI---KGPRMPLGFTFSFPCQQTSLDAGILI 617 Query: 550 KWTKAFSIEDAVGKDVVAELQ 612 WTK F D VG DVV L+ Sbjct: 618 TWTKGFKATDCVGHDVVTLLR 638 Score = 97.1 bits (240), Expect = 4e-20 Identities = 57/156 (36%), Positives = 81/156 (51%), Gaps = 2/156 (1%) Frame = +1 Query: 139 LRDVAAAMADEMCAGLEKEGG--SRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKV 312 L D+ EM GL ++ + VKML ++V +P G E G F LDLGG++FR+L+V Sbjct: 36 LIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRV 95 Query: 313 QLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLEL 492 Q+ + ES P +++ GS S+LF +A L F+ + KKL + Sbjct: 96 QVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRK-----IKDKKLPV 150 Query: 493 GFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVV 600 GFTFSFP +Q + L+ WTK F G DVV Sbjct: 151 GFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVV 186
>HXK_DEBOC (P50506) Hexokinase (EC 2.7.1.1)| Length = 478 Score = 114 bits (285), Expect = 2e-25 Identities = 68/158 (43%), Positives = 93/158 (58%) Frame = +1 Query: 139 LRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQL 318 LR + E+ GL K+GG+ + M+ +V PTG+E G + +DLGGTN RV+ V+L Sbjct: 41 LRKITDHFISELEKGLSKQGGN-IPMIPGWVMDFPTGKEMGDYLAIDLGGTNLRVVLVKL 99 Query: 319 GGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGF 498 GGN ++ + A+P ++ + S EL+ FIA L KFV +E + LSN L LGF Sbjct: 100 GGNRDFDTTQS--KFALPENMRTAKSEELWEFIAECLQKFVEEEFRNGVLSN---LPLGF 154 Query: 499 TFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 TFS+P Q S+ G L +WTK F IE G DVV LQ Sbjct: 155 TFSYPASQGSINEGYLQRWTKGFDIEGVEGHDVVPMLQ 192
>HXK1_BOVIN (P27595) Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Brain| form hexokinase) Length = 918 Score = 113 bits (282), Expect = 5e-25 Identities = 74/201 (36%), Positives = 105/201 (52%), Gaps = 8/201 (3%) Frame = +1 Query: 34 VISP*SAGRASGAPVAMAEQLVADLREKCDTPVSL------LRDVAAAMADEMCAGLEKE 195 ++S G+ + A+A +L R+ +T L +V + EM GL KE Sbjct: 443 LLSESGTGKGAAMVTAVAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKE 502 Query: 196 GGSR--VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAI 369 S V ML S++ +P G EDG F LDLGGTNFRVL V++ K + ++ I Sbjct: 503 TNSNATVNMLPSFLRSIPDGTEDGDFLALDLGGTNFRVLLVKIRSGKKSTVEMHNKIYRI 562 Query: 370 PPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLV 549 P +M G+ ELF I S ++ F+ + G G ++ LGFTFSFP +Q S+ +G L+ Sbjct: 563 PIEIMQGTGEELFDHIVSCISDFL--DYMGI---KGPRMPLGFTFSFPCQQTSLDAGILI 617 Query: 550 KWTKAFSIEDAVGKDVVAELQ 612 WTK F D VG DVV L+ Sbjct: 618 TWTKGFKATDCVGHDVVTLLR 638 Score = 97.4 bits (241), Expect = 3e-20 Identities = 58/156 (37%), Positives = 81/156 (51%), Gaps = 2/156 (1%) Frame = +1 Query: 139 LRDVAAAMADEMCAGLEKEGG--SRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKV 312 L D+ EM GL ++ + VKML ++V +P G E G F LDLGG++FR+L+V Sbjct: 36 LLDIMNRFKKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRV 95 Query: 313 QLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLEL 492 Q+ + ES P ++M GS S+LF + L F+ ++ KKL + Sbjct: 96 QVNHEQNRPVHMESEVYDTPENIMHGSGSQLFDHVLECLGDFMEKKK-----IKDKKLPV 150 Query: 493 GFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVV 600 GFTFSFP RQ + L+ WTK F A G VV Sbjct: 151 GFTFSFPCRQSKIDQAILITWTKRFKARGAEGNYVV 186
>HXK2_DROME (Q9NFT7) Hexokinase type 2 (EC 2.7.1.1)| Length = 486 Score = 113 bits (282), Expect = 5e-25 Identities = 70/160 (43%), Positives = 94/160 (58%), Gaps = 2/160 (1%) Frame = +1 Query: 139 LRDVAAAMADEMCAGLEKEGGSR--VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKV 312 + +V M E+ GL K+ +R +K +S+V LPTG+E G + LDLGG+NFRVL V Sbjct: 56 MTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDLGGSNFRVLLV 115 Query: 313 QLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLEL 492 L N + S+ P LMSGS LF F+A L++F L N + L L Sbjct: 116 NLISNSD--VETMSKGYNFPQTLMSGSGKALFDFLAECLSEFCHSH----GLEN-ESLAL 168 Query: 493 GFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 GFTFSFP++Q+ ++ G LV WTK FS E VGK+VV+ LQ Sbjct: 169 GFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQ 208
>HXK1_RAT (P05708) Hexokinase-1 (EC 2.7.1.1) (Hexokinase type I) (HK I) (Brain| form hexokinase) Length = 918 Score = 110 bits (274), Expect = 4e-24 Identities = 72/201 (35%), Positives = 104/201 (51%), Gaps = 8/201 (3%) Frame = +1 Query: 34 VISP*SAGRASGAPVAMAEQLVADLREKCDTPVSL------LRDVAAAMADEMCAGLEKE 195 ++S G+ + A+A +L R+ +T L +V + EM GL KE Sbjct: 443 LLSESGTGKGAAMVTAVAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKE 502 Query: 196 GGSR--VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAI 369 S+ VKML S+V +P G E G F LDLGGTNFRVL V++ K + ++ +I Sbjct: 503 TNSKATVKMLPSFVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSI 562 Query: 370 PPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLV 549 P +M G+ ELF I S ++ F+ + G G ++ LGFTFSFP Q ++ G L+ Sbjct: 563 PLEIMQGTGDELFDHIVSCISDFL--DYMGI---KGPRMPLGFTFSFPCHQTNLDCGILI 617 Query: 550 KWTKAFSIEDAVGKDVVAELQ 612 WTK F D G DV + L+ Sbjct: 618 SWTKGFKATDCEGHDVASLLR 638 Score = 100 bits (249), Expect = 3e-21 Identities = 58/157 (36%), Positives = 84/157 (53%), Gaps = 2/157 (1%) Frame = +1 Query: 136 LLRDVAAAMADEMCAGLEKEGG--SRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLK 309 +L D+ EM GL ++ + VKML ++V +P G E G F LDLGG++FR+L+ Sbjct: 35 ILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILR 94 Query: 310 VQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLE 489 VQ+ +S ES P +++ GS ++LF +A L F+ ++ KKL Sbjct: 95 VQVNHEKNQNVSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEKKK-----IKDKKLP 149 Query: 490 LGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVV 600 +GFTFSFP RQ + L+ WTK F G DVV Sbjct: 150 VGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVV 186
>HXKG_ASPNG (Q92407) Glucokinase (EC 2.7.1.2) (Glucose kinase) (GLK)| Length = 495 Score = 107 bits (267), Expect = 3e-23 Identities = 67/184 (36%), Positives = 101/184 (54%), Gaps = 13/184 (7%) Frame = +1 Query: 100 ADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLD 279 A + + D P + ++ E+ GL KE + + + +YV +P G E GL+ +D Sbjct: 10 ARIARQFDYPAAEVQRGVTEYIREIDEGLSKEH-TTLSQIPTYVTAVPNGTEKGLYLAVD 68 Query: 280 LGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLM-SGSSSELFAFIASELAKFVTDEE- 453 LGGTNFRV + L G+ +++ ++ IP M SG++ +LF F+A ++ F+ Sbjct: 69 LGGTNFRVCSIDLHGDTTFSLTQS--KIMIPRETMASGTAKDLFLFLARQIESFLRIHHN 126 Query: 454 -------KGTSLSNGK----KLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVV 600 + + NG +LGFTFSFPVRQ + GTL++WTK F+I DAVGKDV Sbjct: 127 DHFEAHLRRRNEKNGNCEEDLFDLGFTFSFPVRQLGINKGTLIRWTKGFNIPDAVGKDVC 186 Query: 601 AELQ 612 A LQ Sbjct: 187 ALLQ 190
>HXK2_MOUSE (O08528) Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II)| Length = 917 Score = 106 bits (264), Expect = 6e-23 Identities = 75/195 (38%), Positives = 100/195 (51%), Gaps = 8/195 (4%) Frame = +1 Query: 52 AGRASGAPVAMAEQLVADLREKCDTPVSL------LRDVAAAMADEMCAGLEKEG--GSR 207 +G+ + A+A +L R + T SL L +V M EM GL KE + Sbjct: 449 SGKGAAMVTAVAYRLADQHRARQKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHEAAP 508 Query: 208 VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMS 387 VKML +YV P G E G F LDLGGTNFRVL V++ + + ++ +IP +M Sbjct: 509 VKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMH 568 Query: 388 GSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAF 567 G+ ELF I +A F+ E G G L LGFTFSFP +Q S+ L+KWTK F Sbjct: 569 GTGEELFDHIVQCIADFL--EYMG---MKGVSLPLGFTFSFPCQQNSLDQSILLKWTKGF 623 Query: 568 SIEDAVGKDVVAELQ 612 G+DVV L+ Sbjct: 624 KASGCEGEDVVTLLK 638 Score = 102 bits (255), Expect = 7e-22 Identities = 67/175 (38%), Positives = 89/175 (50%) Frame = +1 Query: 76 VAMAEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGRE 255 V +Q + +R +T + + R M E G + VKML ++V P G E Sbjct: 19 VQKVDQYLYHMRLSDETLLEISRRFRKEM--EKGLGATTHPTAAVKMLPTFVRSTPDGTE 76 Query: 256 DGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAK 435 G F LDLGGTNFRVL+V++ N + E++ AIP +M GS ++LF IA LA Sbjct: 77 HGEFLALDLGGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136 Query: 436 FVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVV 600 F+ + KKL LGFTFSFP Q + LV WTK F G+DVV Sbjct: 137 FMDKLQ-----IKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVV 186
>HXK2_RAT (P27881) Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II)| Length = 917 Score = 105 bits (263), Expect = 8e-23 Identities = 75/195 (38%), Positives = 100/195 (51%), Gaps = 8/195 (4%) Frame = +1 Query: 52 AGRASGAPVAMAEQLVADLREKCDTPVSL------LRDVAAAMADEMCAGLEKE--GGSR 207 +G+ + A+A +L R + T SL L +V M EM GL KE + Sbjct: 449 SGKGAAMVTAVAYRLADQHRARQKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHAVAP 508 Query: 208 VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMS 387 VKML +YV P G E G F LDLGGTNFRVL V++ + + ++ +IP +M Sbjct: 509 VKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMH 568 Query: 388 GSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAF 567 G+ ELF I +A F+ E G G L LGFTFSFP +Q S+ L+KWTK F Sbjct: 569 GTGEELFDHIVQCIADFL--EYMG---MKGVSLPLGFTFSFPCQQNSLDQSILLKWTKGF 623 Query: 568 SIEDAVGKDVVAELQ 612 G+DVV L+ Sbjct: 624 KASGCEGEDVVTLLK 638 Score = 103 bits (256), Expect = 5e-22 Identities = 67/175 (38%), Positives = 89/175 (50%) Frame = +1 Query: 76 VAMAEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGRE 255 V +Q + +R +T + + R M E G + VKML ++V P G E Sbjct: 19 VQKVDQFLYHMRLSDETLLEISRRFRKEM--EKGLGATTHPTAAVKMLPTFVRSTPDGTE 76 Query: 256 DGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAK 435 G F LDLGGTNFRVL+V++ N + E++ AIP +M GS ++LF IA LA Sbjct: 77 HGEFLALDLGGTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136 Query: 436 FVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVV 600 F+ + KKL LGFTFSFP Q + LV WTK F G+DVV Sbjct: 137 FMDKLQ-----IKEKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVV 186
>HXKA_YEAST (P04806) Hexokinase-1 (EC 2.7.1.1) (Hexokinase-A) (Hexokinase PI)| Length = 485 Score = 105 bits (261), Expect = 1e-22 Identities = 62/159 (38%), Positives = 88/159 (55%), Gaps = 1/159 (0%) Frame = +1 Query: 139 LRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQL 318 LR V DE+ GL K+GG+ + M+ +V + PTG+E G + +DLGGTN RV+ V+L Sbjct: 41 LRKVVKHFIDELNKGLTKKGGN-IPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKL 99 Query: 319 GGNDKHVISRESREVAIPPHLMSGS-SSELFAFIASELAKFVTDEEKGTSLSNGKKLELG 495 GN H + +P + + EL++FIA L F+ ++E L+ L LG Sbjct: 100 SGN--HTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQEL---LNTKDTLPLG 154 Query: 496 FTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 FTFS+P Q + G L +WTK F I + G DVV LQ Sbjct: 155 FTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQ 193
>HXK2_HUMAN (P52789) Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II)| (Muscle form hexokinase) Length = 917 Score = 103 bits (257), Expect = 4e-22 Identities = 75/195 (38%), Positives = 98/195 (50%), Gaps = 8/195 (4%) Frame = +1 Query: 52 AGRASGAPVAMAEQLVADLREKCDTPVSL------LRDVAAAMADEMCAGLEKE--GGSR 207 +G+ + A+A +L R + T L L +V M EM GL KE + Sbjct: 449 SGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAP 508 Query: 208 VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMS 387 VKML +YV P G E G F LDLGGTNFRVL V++ + ++ AIP +M Sbjct: 509 VKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMH 568 Query: 388 GSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAF 567 G+ ELF I +A F+ E G G L LGFTFSFP +Q S+ L+KWTK F Sbjct: 569 GTGDELFDHIVQCIADFL--EYMG---MKGVSLPLGFTFSFPCQQNSLDESILLKWTKGF 623 Query: 568 SIEDAVGKDVVAELQ 612 G+DVV L+ Sbjct: 624 KASGCEGEDVVTLLK 638 Score = 102 bits (254), Expect = 9e-22 Identities = 60/132 (45%), Positives = 74/132 (56%) Frame = +1 Query: 208 VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMS 387 VKML ++V P G E G F LDLGGTNFRVL V++ N + E++ AIP +M Sbjct: 61 VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR 120 Query: 388 GSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAF 567 GS ++LF IA LA F+ + KKL LGFTFSFP Q + LV WTK F Sbjct: 121 GSGTQLFDHIAECLANFMDKLQ-----IKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGF 175 Query: 568 SIEDAVGKDVVA 603 G+DVVA Sbjct: 176 KSSGVEGRDVVA 187
>EMI2_YEAST (Q04409) Glucokinase EMI2 (EC 2.7.1.2) (Glucose kinase) (GLK)| (Early meiotic induction protein 2) Length = 500 Score = 102 bits (255), Expect = 7e-22 Identities = 60/146 (41%), Positives = 82/146 (56%), Gaps = 6/146 (4%) Frame = +1 Query: 181 GLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESRE 360 G EK + M+ +YV LP G E G+ DLGGT+FRV V L G+ + + Sbjct: 53 GEEKTVDKGLPMIPTYVTSLPNGTERGVLLAADLGGTHFRVCSVTLNGDG--TFDMQQLK 110 Query: 361 VAIPPHLMSG---SSSELFAFIASELAKFVTDEEKGTSLSNG---KKLELGFTFSFPVRQ 522 IP ++ +S ELF+++ FV S G K L++GFTFS+PV Q Sbjct: 111 SKIPEEYLNDKDVTSEELFSYLGRRTRAFVRKHHPELLKSTGENIKPLKMGFTFSYPVDQ 170 Query: 523 RSVASGTLVKWTKAFSIEDAVGKDVV 600 S++SGTL++WTK+F IED VGKDVV Sbjct: 171 TSLSSGTLIRWTKSFKIEDTVGKDVV 196
>HXK1_SCHPO (Q09756) Hexokinase-1 (EC 2.7.1.1)| Length = 484 Score = 102 bits (253), Expect = 1e-21 Identities = 62/165 (37%), Positives = 87/165 (52%) Frame = +1 Query: 103 DLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDL 282 +L E+ P LL V E+ GL G V M+ +++ P G E G + LDL Sbjct: 33 ELEEQFTIPTELLHRVTDRFVSELYKGLTTNPGD-VPMVPTWIIGTPDGNEHGSYLALDL 91 Query: 283 GGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGT 462 GGTN RV V++ GN K I++ + +P L G+ LF +IA + KFV + G Sbjct: 92 GGTNLRVCAVEVQGNGKFDITQS--KYRLPQELKVGTREALFDYIADCIKKFVEEVHPGK 149 Query: 463 SLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDV 597 S + LE+GFTFS+P QRS+ +LV WTK F I+ G+ V Sbjct: 150 S----QNLEIGFTFSYPCVQRSINDASLVAWTKGFDIDGVEGESV 190
>HXK4_HUMAN (P35557) Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type| IV) (HK IV) (HK4) (Hexokinase-D) Length = 465 Score = 101 bits (252), Expect = 2e-21 Identities = 69/189 (36%), Positives = 100/189 (52%), Gaps = 4/189 (2%) Frame = +1 Query: 58 RASGAPVAMAEQLVADLREKCDTPVSLLRDVAAAMADEMCAGL--EKEGGSRVKMLLSYV 231 R A EQ++A+ + + + L+ V M EM GL E + VKML +YV Sbjct: 7 RMEAAKKEKVEQILAEFQLQEED----LKKVMRRMQKEMDRGLRLETHEEASVKMLPTYV 62 Query: 232 DKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESRE--VAIPPHLMSGSSSEL 405 P G E G F LDLGGTNFRV+ V++G ++ S +++ +IP M+G++ L Sbjct: 63 RSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEML 122 Query: 406 FAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAV 585 F +I+ ++ F+ + KKL LGFTFSFPVR + G L+ WTK F A Sbjct: 123 FDYISECISDFLDKHQM-----KHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAE 177 Query: 586 GKDVVAELQ 612 G +VV L+ Sbjct: 178 GNNVVGLLR 186
>HXK3_HUMAN (P52790) Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III)| Length = 923 Score = 100 bits (249), Expect = 3e-21 Identities = 78/208 (37%), Positives = 103/208 (49%), Gaps = 6/208 (2%) Frame = +1 Query: 7 LSPLYCFSSVISP*SAGRASGAPVAMAEQLVADLR--EKCDTPVSLLRD----VAAAMAD 168 L+P S + S GR A+A +L A R E+ P L D V A M Sbjct: 447 LAPECDVSLIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRK 506 Query: 169 EMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISR 348 M GL E S ++ML ++V P G E G F LDLGGTNFRVL V++ + Sbjct: 507 AMAKGLRGEASS-LRMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTG----VQI 561 Query: 349 ESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRS 528 S +IP + GS +LF I + F +++G S G+ L LGFTFSFP RQ Sbjct: 562 TSEIYSIPETVAQGSGQQLFDHIVDCIVDF--QQKQGLS---GQSLPLGFTFSFPCRQLG 616 Query: 529 VASGTLVKWTKAFSIEDAVGKDVVAELQ 612 + G L+ WTK F D G+DVV+ L+ Sbjct: 617 LDQGILLNWTKGFKASDCEGQDVVSLLR 644 Score = 90.5 bits (223), Expect = 3e-18 Identities = 60/180 (33%), Positives = 92/180 (51%), Gaps = 4/180 (2%) Frame = +1 Query: 85 AEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSR--VKMLLSYVDKLPTGRED 258 + +LV + ++ + L+ + A++ M L + V+ML +YV P G E Sbjct: 29 SSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQ 88 Query: 259 GLFYGLDLG--GTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELA 432 G F L+LG G + RVL V L G + H + S+E IP +M G+ +LF F A L+ Sbjct: 89 GDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLS 148 Query: 433 KFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 +F+ + N + L+LGF+FSFP Q + TL+ WTK F G+DVV L+ Sbjct: 149 EFLDAQPV-----NKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLR 203
>HXK4_MOUSE (P52792) Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type| IV) (HK IV) (HK4) (Hexokinase-D) Length = 465 Score = 100 bits (249), Expect = 3e-21 Identities = 62/162 (38%), Positives = 89/162 (54%), Gaps = 4/162 (2%) Frame = +1 Query: 139 LRDVAAAMADEMCAGLEKEGGSR--VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKV 312 L+ V + M EM GL+ E VKML +YV P G E G F LDLGGTNFRV+ V Sbjct: 30 LKKVMSRMQKEMDRGLKLETHQEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLV 89 Query: 313 QLGGND--KHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKL 486 ++G + + + + + +IP M+G++ LF +I+ ++ F+ + KKL Sbjct: 90 KVGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQM-----KHKKL 144 Query: 487 ELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 LGFTFSFPVR + G L+ WTK F A G ++V L+ Sbjct: 145 PLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLR 186
>HXKG_YEAST (P17709) Glucokinase GLK1 (EC 2.7.1.2) (Glucose kinase) (GLK)| Length = 500 Score = 100 bits (249), Expect = 3e-21 Identities = 70/185 (37%), Positives = 98/185 (52%), Gaps = 15/185 (8%) Frame = +1 Query: 91 QLVADLREKCDTPVSLLRDVAAAMADEMCAGLE--KEGGSRVK-----MLLSYVDKLPTG 249 Q V + + + L ++ A ++M GL KEG + M+ ++V P G Sbjct: 16 QAVDQICDDFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNG 75 Query: 250 REDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSG---SSSELFAFIA 420 E G+ DLGGTNFR+ V L G+ H S E + IP L+ +S +LF F+A Sbjct: 76 TERGVLLAADLGGTNFRICSVNLHGD--HTFSMEQMKSKIPDDLLDDENVTSDDLFGFLA 133 Query: 421 SE----LAKFVTDE-EKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAV 585 + K+ DE KG + K ++LGFTFS+PV Q S+ SGTL++WTK F I D V Sbjct: 134 RRTLAFMKKYHPDELAKG---KDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTV 190 Query: 586 GKDVV 600 GKDVV Sbjct: 191 GKDVV 195
>HXK4_RAT (P17712) Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type| IV) (HK IV) (HK4) (Hexokinase-D) Length = 465 Score = 99.8 bits (247), Expect = 6e-21 Identities = 62/162 (38%), Positives = 89/162 (54%), Gaps = 4/162 (2%) Frame = +1 Query: 139 LRDVAAAMADEMCAGL--EKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKV 312 L+ V + M EM GL E + VKML +YV P G E G F LDLGGTNFRV+ V Sbjct: 30 LKKVMSRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLV 89 Query: 313 QLGGND--KHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKL 486 ++G + + + + + +IP M+G++ LF +I+ ++ F+ + KKL Sbjct: 90 KVGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQM-----KHKKL 144 Query: 487 ELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 LGFTFSFPVR + G L+ WTK F A G ++V L+ Sbjct: 145 PLGFTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNIVGLLR 186
>HXK3_RAT (P27926) Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III)| Length = 924 Score = 99.4 bits (246), Expect = 7e-21 Identities = 75/204 (36%), Positives = 102/204 (50%), Gaps = 6/204 (2%) Frame = +1 Query: 7 LSPLYCFSSVISP*SAGRASGAPVAMAEQLVADLR--EKCDTPVSL----LRDVAAAMAD 168 L+P S + S GR A+A +L R E+ P L L V A M + Sbjct: 447 LAPECDVSFIPSVDGGGRGVAMVTAVAARLATHRRILEETLAPFQLSLEQLTAVQAQMRE 506 Query: 169 EMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISR 348 M GL+ E S ++ML +YV P G E G F LDLGGTNFRVL V++ + ++ Sbjct: 507 AMIRGLQGESSS-LRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEGSVQITNQ 565 Query: 349 ESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRS 528 +IP ++ GS +LF I + D +K LS G+ L LGFTFSFP +Q Sbjct: 566 V---YSIPEYVAQGSGQKLFDHIVD----CIVDFQKRQGLS-GQSLPLGFTFSFPCKQLG 617 Query: 529 VASGTLVKWTKAFSIEDAVGKDVV 600 + G L+ WTK F+ G+DVV Sbjct: 618 LDQGILLNWTKGFNASGCEGQDVV 641 Score = 86.3 bits (212), Expect = 7e-17 Identities = 59/181 (32%), Positives = 91/181 (50%), Gaps = 7/181 (3%) Frame = +1 Query: 91 QLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSR--VKMLLSYVDKLPTGREDGL 264 +L + ++ ++ L+ + A++ M L+ + V+ML +YV P G E G Sbjct: 31 ELAQEYLQQFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGD 90 Query: 265 FYGLDLG--GTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKF 438 F L+LG G + RVL V L G +H + S+E IP ++ G+ +LF F A L++F Sbjct: 91 FLVLELGATGASLRVLWVTLTGTKEHSVETRSQEFVIPQEVILGAGQQLFDFAARCLSEF 150 Query: 439 VTD---EEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 + E +G L+LGF FSFP Q + TL+ WTK F G+DVV L Sbjct: 151 LDAYPVENQG--------LKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLL 202 Query: 610 Q 612 + Sbjct: 203 R 203
>HXK3_MOUSE (Q3TRM8) Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III)| Length = 922 Score = 99.0 bits (245), Expect = 1e-20 Identities = 76/204 (37%), Positives = 102/204 (50%), Gaps = 6/204 (2%) Frame = +1 Query: 7 LSPLYCFSSVISP*SAGRASGAPVAMAEQLVADLR--EKCDTPVSLLRD----VAAAMAD 168 L+P S + S GR A+A +L A R E+ P L + V A M + Sbjct: 445 LAPNCDVSFIPSVDGGGRGVAMVTAVAARLAAHRRILEETLAPFQLTLEQMTVVQAQMRE 504 Query: 169 EMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISR 348 M GL+ E S ++ML +YV P G E G F LDLGGTNFRVL V++ +I++ Sbjct: 505 AMIRGLQGEASS-LRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEGSVQIINQ 563 Query: 349 ESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRS 528 +IP GS +LF I + D +K LS G+ L LGFTFSFP +Q Sbjct: 564 V---YSIPECRAQGSGQKLFDHIVD----CIVDFQKRQGLS-GQSLPLGFTFSFPCKQLG 615 Query: 529 VASGTLVKWTKAFSIEDAVGKDVV 600 + G L+ WTK F+ G+DVV Sbjct: 616 LDQGILLNWTKGFNASGCEGQDVV 639 Score = 81.6 bits (200), Expect = 2e-15 Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 5/140 (3%) Frame = +1 Query: 208 VKMLLSYVDKLPTGREDGLFYGLDLG--GTNFRVLKVQLGGNDKHVISRESREVAIPPHL 381 V+ML +YV P G E G F L+LG G + RVL V L G + + SRE IP + Sbjct: 70 VRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKECRVEPRSREFVIPQEV 129 Query: 382 MSGSSSELFAFIASELAKFVTD---EEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVK 552 + G+ +LF F A L++F+ E +G L+LGF FSFP Q + TL+ Sbjct: 130 ILGAGQQLFDFAARCLSEFLDAYPVENQG--------LKLGFNFSFPCHQTGLDRSTLIS 181 Query: 553 WTKAFSIEDAVGKDVVAELQ 612 WTK F G+DVV L+ Sbjct: 182 WTKGFRCSGVEGQDVVQLLR 201
>HXKB_YEAST (P04807) Hexokinase-2 (EC 2.7.1.1) (Hexokinase-B) (Hexokinase PII)| Length = 485 Score = 98.2 bits (243), Expect = 2e-20 Identities = 65/186 (34%), Positives = 97/186 (52%) Frame = +1 Query: 55 GRASGAPVAMAEQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVD 234 G + P + +Q + + + P L+ V E+ GL K+GG+ + M+ +V Sbjct: 13 GSMADVPKELMQQ-IENFEKIFTVPTETLQAVTKHFISELEKGLSKKGGN-IPMIPGWVM 70 Query: 235 KLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAF 414 PTG+E G F +DLGGTN RV+ V+LGG D+ + +S+ + + EL+ F Sbjct: 71 DFPTGKESGDFLAIDLGGTNLRVVLVKLGG-DRTFDTTQSKYRLPDAMRTTQNPDELWEF 129 Query: 415 IASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKD 594 IA L F+ DE+ +S + + LGFTFSFP Q + G L +WTK F I + D Sbjct: 130 IADSLKAFI-DEQFPQGIS--EPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHD 186 Query: 595 VVAELQ 612 VV LQ Sbjct: 187 VVPMLQ 192
>HXK1_DROME (Q9NFT9) Hexokinase type 1 (EC 2.7.1.1)| Length = 465 Score = 90.1 bits (222), Expect = 5e-18 Identities = 59/160 (36%), Positives = 89/160 (55%), Gaps = 2/160 (1%) Frame = +1 Query: 139 LRDVAAAMADEMCAGLEKEGGSR--VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKV 312 L + AM E+ GL ++ R V LSYV LPTGRE G F L++ TN R++ V Sbjct: 28 LEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQFLALEMMPTNCRIMLV 87 Query: 313 QLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLEL 492 + + + I S+ V +P + +G +E+F F+A+ +A FV +EK N L L Sbjct: 88 KF--SSERDIYTSSKCVIMPHTVAAGRGTEVFTFLATSIANFV--KEKKVDKDN---LPL 140 Query: 493 GFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKDVVAELQ 612 G F+F +++ ++ G LV WTK F + A+GKDVV L+ Sbjct: 141 GIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLR 180
>HXKL_ARATH (Q9T071) Probable hexokinase (EC 2.7.1.1)| Length = 493 Score = 85.9 bits (211), Expect = 9e-17 Identities = 56/175 (32%), Positives = 95/175 (54%), Gaps = 1/175 (0%) Frame = +1 Query: 88 EQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLF 267 ++++ +C TPVS L VA A+ +M A L E + ML+S+ LP+G E G+ Sbjct: 39 QRILRKFARECATPVSKLWAVADALVADMTASLTAECCGSLNMLVSFTGSLPSGDEKGVH 98 Query: 268 YGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTD 447 YG++L G +L+ LGGN++ + + E+ IP +++GS EL FI+ EL KF+ Sbjct: 99 YGVNLRGKELLLLRGTLGGNEEPISDVQKHEIPIPDDVLNGSFKELCDFISLELVKFLAM 158 Query: 448 EEKGTSLSNGKKLELGFTFSFPVRQ-RSVASGTLVKWTKAFSIEDAVGKDVVAEL 609 G + + LGFT + V Q S + ++ + + A ++ V KD+V ++ Sbjct: 159 NPGGEA---EEVKNLGFTLTRSVEQIGSHSISSIHRKSLANDDDEKVLKDLVNDM 210
>HXK2_SCHPO (P50521) Hexokinase-2 (EC 2.7.1.1)| Length = 455 Score = 82.4 bits (202), Expect = 9e-16 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 1/170 (0%) Frame = +1 Query: 88 EQLVADLREKCDTPVSLLRDVAAAMADEMCAGLEKEGGSRVKMLLSYVDKLPTGREDGLF 267 +Q V L + P LR+ + GL+K G + M +++ LPTG E G F Sbjct: 6 QQAVKKLVNDFEYPTESLREAVKEFDELRQKGLQKNG-EVLAMAPAFISTLPTGAETGDF 64 Query: 268 YGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASELAKFVTD 447 LD GGTN RV +QL G+ K+ + + S+ V + + S + F++ + F+ + Sbjct: 65 LALDFGGTNLRVCWIQLLGDGKYEM-KHSKSVLPRECVRNESVKPIIDFMSDHVELFIKE 123 Query: 448 E-EKGTSLSNGKKLELGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGKD 594 + L +GFTFS+P Q S+ L++WTK +I +A+ KD Sbjct: 124 HFPSKFGCPEEEYLPMGFTFSYPANQVSITESYLLRWTKGLNIPEAINKD 173
>HXK_PLAFA (Q02155) Hexokinase (EC 2.7.1.1)| Length = 493 Score = 69.3 bits (168), Expect = 8e-12 Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 8/137 (5%) Frame = +1 Query: 211 KMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHL--- 381 KML S + +PTG+E G +Y +D GGTNFR ++ L G K +E+ + Sbjct: 80 KMLDSCIANIPTGQEKGTYYAIDFGGTNFRAVRASLDGKGKIKRDQETYSLKFTGSYSHE 139 Query: 382 -----MSGSSSELFAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVASGTL 546 ++S+LF A E K++ E L N + +GFTFSFP S+ L Sbjct: 140 KGLLDKHATASQLFDHFA-ERIKYIMGE--FNDLDNKEVKSVGFTFSFPCTSPSINCSIL 196 Query: 547 VKWTKAFSIEDAVGKDV 597 + WTK F A V Sbjct: 197 IDWTKGFETGRATNDPV 213
>HXK1_ASPFU (Q4U3Y2) Hexokinase-1 (EC 2.7.1.1) (Hexokinase I)| Length = 549 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/126 (30%), Positives = 65/126 (51%), Gaps = 4/126 (3%) Frame = +1 Query: 202 SRVKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGG-NDKHVISRESREVAIPPH 378 S V ML SY LP+G E G + LD+GG+ FRV ++LGG ++ S + Sbjct: 92 SPVCMLPSYNHALPSGTEKGTYLALDVGGSTFRVALIELGGAGAMKILQESSSPIDNDVK 151 Query: 379 LMSGSSSELFAFIASELAKFVTDEEKGTSLSNGKK---LELGFTFSFPVRQRSVASGTLV 549 L+ G+ F ++A ++ ++ G++ L +G ++SFP+ Q S++SG ++ Sbjct: 152 LLEGTL--FFDWMAEKIESMLS----AVGADYGREAVPLSMGLSWSFPIEQTSISSGLVI 205 Query: 550 KWTKAF 567 K F Sbjct: 206 HMGKGF 211
>HXK_TOXGO (Q969A8) Hexokinase (EC 2.7.1.1)| Length = 468 Score = 56.2 bits (134), Expect = 7e-08 Identities = 47/149 (31%), Positives = 65/149 (43%), Gaps = 15/149 (10%) Frame = +1 Query: 208 VKMLLSYVDKLPTGREDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMS 387 +KML S V LPTG E G Y +D GG+ R ++ L G K I ++ + H + Sbjct: 62 MKMLDSCVSNLPTGAEVGEAYAIDFGGSTCRAVRCSLLGKGKMEIIQDKICLRSAEHRCA 121 Query: 388 -------GSSSEL---FAFIASELAKFVTDEEKGTSLSNGKKLELGFTFSFPVRQRSVAS 537 EL FA L D +K + + +GFTFSFP Q ++ S Sbjct: 122 KGFMDKKAGGKELFDQFAMCIRGLMDRSGDLKKAEETNT--PVPVGFTFSFPCAQAALNS 179 Query: 538 GTLVKWTKAFSI-----EDAVGKDVVAEL 609 L++WTK F + GKDV L Sbjct: 180 SFLIEWTKGFETGRENPDRVEGKDVAVLL 208
>TERT_YEAST (Q06163) Telomerase reverse transcriptase (EC 2.7.7.49) (Telomerase| catalytic subunit) Length = 884 Score = 33.5 bits (75), Expect = 0.50 Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Frame = -2 Query: 530 TDRCLTGKENVNPNSSFFPFDKLVPFSSSVTNLAN-SEAMKANNSEELP 387 T++ K N+N +SSFFP+ K++P SSS+ L + EA+ N ++P Sbjct: 183 TNKQFLHKLNIN-SSSFFPYSKILPSSSSIKKLTDLREAIFPTNLVKIP 230
>TOC75_PEA (Q43715) Protein TOC75, chloroplast precursor (75 kDa translocon at| the outer-envelope-membrane of chloroplasts) (Import intermediate associated protein of 75 kDa) (75 kDa chloroplast outer envelope protein) Length = 809 Score = 31.2 bits (69), Expect = 2.5 Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 4/118 (3%) Frame = +1 Query: 250 REDGLFYGLDLGGTNFRVLKVQLGGNDKHVISRESREVAIPPHLMSGSSSELFAFIASEL 429 R+ YGL + R + N + V+ + PP +SG+ + AF+ + + Sbjct: 566 RQSKFTYGLVMEEIITRDESNHICSNGQRVLPNGAISADGPPTTLSGTGIDRMAFLQANI 625 Query: 430 AKFVTDEEKGTSLSNGKKLE----LGFTFSFPVRQRSVASGTLVKWTKAFSIEDAVGK 591 + T GT + + + LG +FP R T+ K+ + S+E+ GK Sbjct: 626 TRDNTRFVNGTIVGSRNMFQVDQGLGVGSNFPFFNRHQL--TVTKFLQLMSVEEGAGK 681
>ATG20_ASHGO (Q75B65) Autophagy-related protein 20| Length = 577 Score = 30.8 bits (68), Expect = 3.3 Identities = 19/56 (33%), Positives = 25/56 (44%) Frame = -1 Query: 294 VCPS*VQSIEQTVLSPGGELVDVGEQHLDPAPTLLLQPGAHLVGHGRRHVAQQRHG 127 VC S +Q L G + VGE DP T ++Q V HG+ +VA G Sbjct: 12 VCASSIQPARNGGLCGHGGVGGVGEAEGDPVHTQIIQEDNPFVEHGQSYVAPHSGG 67
>EGFL8_HUMAN (Q99944) EGF-like domain-containing protein 8 precursor (Epidermal| growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2) Length = 293 Score = 30.8 bits (68), Expect = 3.3 Identities = 14/37 (37%), Positives = 16/37 (43%) Frame = +2 Query: 77 WQWRSSWWLTCGRSATRPCRCCATWRRPWPTRCAPGW 187 W+ R LTC +PC RP CAPGW Sbjct: 100 WKKRHPGALTCEAICAKPCLNGGVCVRPDQCECAPGW 136 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,081,999 Number of Sequences: 219361 Number of extensions: 1561070 Number of successful extensions: 5193 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 4957 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5130 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5481822624 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
