ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags19d22 |
|---|---|
| Clone Library Name | barley_pub |
>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 507 Score = 117 bits (294), Expect = 2e-26 Identities = 62/136 (45%), Positives = 83/136 (61%), Gaps = 4/136 (2%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 +PPF S++ T RKI++WR ++ FP+D LS EA DLI +LL D R+G GA+ IK Sbjct: 368 WPPFCSENAHETYRKIINWRENLYFPEDLHLSAEAEDLIRKLLTSADQRLGRYGANDIKL 427 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMD----NSPPARRGSGPSRKAKL 349 HP+FRGV WD + E+ A F PQ+ DT F + D + NSPP + PS Sbjct: 428 HPFFRGVNWDTIREINAPFIPQLKSITDTSYFEEIDTIPNITMNSPPVLQNKIPSDV--- 484 Query: 350 NSKDLSFVGYTYKNFD 397 ++L+FVGYTYK FD Sbjct: 485 -DQNLAFVGYTYKRFD 499
>CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 716 Score = 109 bits (273), Expect = 5e-24 Identities = 59/140 (42%), Positives = 88/140 (62%), Gaps = 8/140 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGG-AGADQIK 178 +PPF S+ P T RKI++W+ ++ PDD LSPE+ DLI +LL + ++R+G GAD++K Sbjct: 570 WPPFCSETPHETYRKILNWQETLQIPDDIHLSPESEDLIRKLLTNAENRLGRYNGADELK 629 Query: 179 AHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSP--PARRGSGPSRKAKLN 352 HP+FRGV WD + +++A F P++ DT+ F DE++N P PA + R L Sbjct: 630 LHPFFRGVDWDTIRKVDAPFIPKLRSITDTR-FFPTDELENVPDSPALSKAMEQRDQVLQ 688 Query: 353 S-----KDLSFVGYTYKNFD 397 + +DL F+GYTY FD Sbjct: 689 NGGNVKEDLPFIGYTYSRFD 708
>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 588 Score = 108 bits (269), Expect = 1e-23 Identities = 57/133 (42%), Positives = 80/133 (60%), Gaps = 1/133 (0%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGG-AGADQIK 178 +PPF S+ P T KI++WR ++FPDD LSPE+ DLI RLL ++R+G GA++IK Sbjct: 453 WPPFCSEQPRETYHKIINWRETLQFPDDVHLSPESEDLIRRLLTSSENRLGRIGGANEIK 512 Query: 179 AHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSK 358 +HP+FRGV W + E A F P+++ DT F + D S ++ S R S Sbjct: 513 SHPFFRGVDWSSIREFNAPFVPKLSSITDTSYFPTDELGDVSEYPQQSSRSDR-----SS 567 Query: 359 DLSFVGYTYKNFD 397 DL F+GYT+ FD Sbjct: 568 DLPFIGYTFSRFD 580
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 107 bits (268), Expect = 2e-23 Identities = 54/140 (38%), Positives = 86/140 (61%), Gaps = 8/140 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 +PPF ++D T RKIV+WR+ + FPDD L +A +LI L+C+ ++R+G GA +IK+ Sbjct: 455 WPPFCAEDSHDTYRKIVNWRHSLYFPDDITLGVDAENLIRSLICNTENRLGRGGAHEIKS 514 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFM--KFDEMDNS------PPARRGSGPSR 337 H +FRGV +D L + A F+P++ +DT F + D+ DN+ AR + P++ Sbjct: 515 HAFFRGVEFDSLRRIRAPFEPRLTSAIDTTYFPTDEIDQTDNATLLKAQQAARGAAAPAQ 574 Query: 338 KAKLNSKDLSFVGYTYKNFD 397 + + L F+GYT+K FD Sbjct: 575 QEESPELSLPFIGYTFKRFD 594
>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell| wall biosynthesis kinase) Length = 756 Score = 106 bits (265), Expect = 4e-23 Identities = 59/142 (41%), Positives = 86/142 (60%), Gaps = 10/142 (7%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIG-GAGADQIK 178 +PPF S+ P T RKI+++ ++FPDD +S EA DLI RLL D R+G GAD+IK Sbjct: 608 WPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIK 667 Query: 179 AHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSP--PARRGSGPSRKAKLN 352 +HP+FRGV W+ + ++EA + P+++ DT+ F DE++N P PA + R+ Sbjct: 668 SHPFFRGVDWNTIRQVEAPYIPKLSSITDTR-FFPTDELENVPDSPAMAQAAKQREQMTK 726 Query: 353 -------SKDLSFVGYTYKNFD 397 +DL F+GYTY FD Sbjct: 727 QGGSAPVKEDLPFIGYTYSRFD 748
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 106 bits (264), Expect = 6e-23 Identities = 53/134 (39%), Positives = 77/134 (57%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 YPPF S+ P T RK+++W+ + FP + +S +A+DLI R D ++RIG +G ++IK Sbjct: 320 YPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKG 379 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 HP+F GV W+ + E AA ++ DT NF F E D P + P K SKD Sbjct: 380 HPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDILQPVPNTTEPDYK----SKD 435 Query: 362 LSFVGYTYKNFDAV 403 F+ YTYK F+ + Sbjct: 436 WVFLNYTYKRFEGL 449
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 105 bits (262), Expect = 9e-23 Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 2/134 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 +PPF S++ T RKI++WR + FP+D LS EARDL+ RL+ D +HR+G GA +I Sbjct: 329 WPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLMTDSEHRLGRGGAIEIMQ 388 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSP--PARRGSGPSRKAKLNS 355 HP+F G+ WD + E A F P + DT ++ DE++ P P + L Sbjct: 389 HPFFTGIDWDHIRETAAPFIPNLKSITDT-HYFPVDELEQVPEQPVTQQPASVDPQTLEQ 447 Query: 356 KDLSFVGYTYKNFD 397 +L+F+GYTYK F+ Sbjct: 448 TNLAFLGYTYKKFN 461
>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 719 Score = 104 bits (260), Expect = 2e-22 Identities = 58/145 (40%), Positives = 84/145 (57%), Gaps = 13/145 (8%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 +PPF S+ P T RKI+++ + FPDD +S EA DLI RLL D R+G GA++IK Sbjct: 568 WPPFCSETPQETYRKIMNFEQTLVFPDDIHISYEAEDLIRRLLSHADERLGRHGANEIKN 627 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSP--PARRGSGPSRKAKLN- 352 HP+FRGV W+ + ++ A + P+++ DT+ F DE++N P PA + R+ L Sbjct: 628 HPFFRGVDWETIRQVGAPYIPKLSSVTDTR-FFPTDELENVPDSPAMAQAAKQREQMLKQ 686 Query: 353 ----------SKDLSFVGYTYKNFD 397 +DL F+GYTY FD Sbjct: 687 GGSAANTAQAKEDLPFIGYTYSRFD 711
>CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 718 Score = 103 bits (257), Expect = 4e-22 Identities = 58/145 (40%), Positives = 87/145 (60%), Gaps = 13/145 (8%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIG-GAGADQIK 178 +PPF S+ P T RKI+++ ++FPDD +S EA DLI RLL ++R+G GAD+IK Sbjct: 567 WPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHSENRLGRHGGADEIK 626 Query: 179 AHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSP--PARRGSGPSRKAKLN 352 AHP+F GV W+ + ++EA + P+++ DT+ F DE++N P PA + R+ + Sbjct: 627 AHPFFSGVDWNTIRQVEAPYIPKLSSVTDTR-FFPTDELENVPDSPAMAQAARQREQMMT 685 Query: 353 ----------SKDLSFVGYTYKNFD 397 +DL F+GYTY FD Sbjct: 686 QQQGVPQSNAKEDLPFIGYTYSRFD 710
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 102 bits (255), Expect = 6e-22 Identities = 57/145 (39%), Positives = 88/145 (60%), Gaps = 13/145 (8%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIG-GAGADQIK 178 +PPF S+ P T RKI+++ ++FP+D +S EA DLI RLL + R+G GAD+IK Sbjct: 622 WPPFCSETPQETYRKIMNFEQTLQFPEDVHISYEAEDLIRRLLTHSNQRLGRQGGADEIK 681 Query: 179 AHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSP--PARRGSGPSRKAKLN 352 +HP+FRGV W+ + ++EA + P+++ DT+ F DE++N P PA + R+ + Sbjct: 682 SHPFFRGVDWNTIRQVEAPYIPKLSSITDTR-FFPTDELENVPDSPAMAQAAKQREQMMK 740 Query: 353 S----------KDLSFVGYTYKNFD 397 + +DL F+GYTY FD Sbjct: 741 NGVNPNQNQVKEDLPFIGYTYSRFD 765
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 102 bits (254), Expect = 8e-22 Identities = 52/134 (38%), Positives = 74/134 (55%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 +PPF S+ P T RK++ W+ + FP + +S +A+DLI R D ++RIG G ++IK Sbjct: 320 FPPFCSETPQETYRKVMSWKETLAFPPEVPVSEKAKDLILRFCTDSENRIGNGGVEEIKG 379 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 HP+F GV W + E AA ++ DT NF F E D P + P K SKD Sbjct: 380 HPFFEGVDWGHIRERPAAIPIEIRSIDDTSNFDDFPESDILQPVPNTTEPDYK----SKD 435 Query: 362 LSFVGYTYKNFDAV 403 F+ YTYK F+ + Sbjct: 436 WVFLNYTYKRFEGL 449
>STK38_HUMAN (Q15208) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 101 bits (252), Expect = 1e-21 Identities = 49/134 (36%), Positives = 77/134 (57%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 YPPF S+ P T +K+++W+ + FP + +S +A+DLI R C+ +HRIG G ++IK+ Sbjct: 319 YPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKS 378 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 + +F GV W+ + E AA ++ DT NF +F E D P S + +KD Sbjct: 379 NSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDILKPTVATSN-HPETDYKNKD 437 Query: 362 LSFVGYTYKNFDAV 403 F+ YTYK F+ + Sbjct: 438 WVFINYTYKRFEGL 451
>STK38_MOUSE (Q91VJ4) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 97.8 bits (242), Expect = 2e-20 Identities = 50/135 (37%), Positives = 76/135 (56%), Gaps = 1/135 (0%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 YPPF S+ P T +K+++W+ + FP + +S +A+ LI R C+ +HRIG G ++IK Sbjct: 319 YPPFCSETPQETYKKVMNWKETLTFPPEVPVSEKAKGLILRFCCEWEHRIGAPGVEEIKN 378 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMD-NSPPARRGSGPSRKAKLNSK 358 + +F GV W+ + E AA ++ DT NF +F E D P S P K +K Sbjct: 379 NLFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDILKPTVTTSSHPETDYK--NK 436 Query: 359 DLSFVGYTYKNFDAV 403 D F+ YTYK F+ + Sbjct: 437 DWVFINYTYKRFEGL 451
>LATS2_HUMAN (Q9NRM7) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase) Length = 1088 Score = 90.1 bits (222), Expect = 4e-18 Identities = 50/138 (36%), Positives = 75/138 (54%), Gaps = 8/138 (5%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + P T K+++W N + P +LSPEARDLI +L C DHR+G GAD +KAH Sbjct: 911 PPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAH 970 Query: 185 PWFRGVAWDK-LYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKA-----K 346 P+F + + + + A + P ++ +DT N FD +D P S S KA Sbjct: 971 PFFSAIDFSSDIRKQPAPYVPTISHPMDTSN---FDPVDEESPWNDASEGSTKAWDTLTS 1027 Query: 347 LNSK--DLSFVGYTYKNF 394 N+K + +F +T++ F Sbjct: 1028 PNNKHPEHAFYEFTFRRF 1045
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 85.5 bits (210), Expect = 1e-16 Identities = 46/127 (36%), Positives = 69/127 (54%), Gaps = 1/127 (0%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSP-EARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY++ + T KI++ +H++FP D P A+DLI +LLC + R+G G D + H Sbjct: 275 PFYAESLVETYGKIMNHEDHLQFPADVTDVPASAQDLIRQLLCRQEERLGRGGLDDFRKH 334 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDL 364 P+F GV W++L A + P++ +DT NF D+ N P PS + L Sbjct: 335 PFFEGVDWERLATSTAPYIPELRGPMDTSNFDVDDDTLNRPET---LPPSSHGAFSGHHL 391 Query: 365 SFVGYTY 385 FVG+TY Sbjct: 392 PFVGFTY 398
>LATS2_MOUSE (Q7TSJ6) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) Length = 1042 Score = 85.5 bits (210), Expect = 1e-16 Identities = 44/114 (38%), Positives = 64/114 (56%), Gaps = 1/114 (0%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + P T K+++W + + P RLS EARDLI +L C D R+G GAD +KAH Sbjct: 869 PPFLAPTPTETQLKVINWESTLHIPTQVRLSAEARDLITKLCCAADCRLGRDGADDLKAH 928 Query: 185 PWFRGVAWDK-LYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKA 343 P+F + + + + + A + P ++ +DT N FD +D P SG S KA Sbjct: 929 PFFNTIDFSRDIRKQPAPYVPTISHPMDTSN---FDPVDEESPWHEASGESAKA 979
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 83.6 bits (205), Expect = 4e-16 Identities = 44/127 (34%), Positives = 67/127 (52%), Gaps = 1/127 (0%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDD-SRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY++ + T KI++ + +FP + +S A+DLI RL+C +HR+G G + K H Sbjct: 281 PFYAESLVETYGKIMNHKERFQFPTQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKH 340 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDL 364 P+F G+ WD + EA + P+V+ DT N FD D+ P + L Sbjct: 341 PFFSGIDWDNIRNCEAPYIPEVSSPTDTSN---FDVDDDCLKNSETMPPPTHTAFSGHHL 397 Query: 365 SFVGYTY 385 FVG+TY Sbjct: 398 PFVGFTY 404
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 83.2 bits (204), Expect = 5e-16 Identities = 45/127 (35%), Positives = 68/127 (53%), Gaps = 1/127 (0%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSP-EARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY++ + T KI++ +H++FP D P A+DLI +LLC + R+G G D + H Sbjct: 275 PFYAESLVETYGKIMNHEDHLQFPPDVPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNH 334 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDL 364 P+F GV W++L A + P++ +DT NF D+ N P P + L Sbjct: 335 PFFEGVDWERLASSTAPYIPELRGPMDTSNFDVDDDTLNHPGT---LPPPSHGAFSGHHL 391 Query: 365 SFVGYTY 385 FVG+TY Sbjct: 392 PFVGFTY 398
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 83.2 bits (204), Expect = 5e-16 Identities = 44/127 (34%), Positives = 67/127 (52%), Gaps = 1/127 (0%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDD-SRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY++ + T KI++ + +FP + +S A+DLI RL+C +HR+G G + K H Sbjct: 281 PFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGIEDFKKH 340 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDL 364 P+F G+ WD + EA + P+V+ DT N FD D+ P + L Sbjct: 341 PFFSGIDWDNIRNCEAPYIPEVSSPTDTSN---FDVDDDCLKNSETMPPPTHTAFSGHHL 397 Query: 365 SFVGYTY 385 FVG+TY Sbjct: 398 PFVGFTY 404
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 82.4 bits (202), Expect = 9e-16 Identities = 51/147 (34%), Positives = 81/147 (55%), Gaps = 2/147 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI++ +N + FPDD+ +S EA++LIC L D + R+G G ++IK H Sbjct: 277 PFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHL 336 Query: 188 WFRG--VAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ AW+ L + A P ++ ++DT NF +E + P KA + ++ Sbjct: 337 FFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEE----DKGDEETFPIPKAFVGNQ- 391 Query: 362 LSFVGYTYKNFDAVKGLKHADMQRSSS 442 L FVG+TY + +A RSSS Sbjct: 392 LPFVGFTYYSNRRYLPSANASENRSSS 418
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/128 (35%), Positives = 74/128 (57%), Gaps = 2/128 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI++ +N + FPDD+ +S EA++LIC L D + R+G G ++IK H Sbjct: 277 PFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHL 336 Query: 188 WFRG--VAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ AW+ L + A P ++ ++DT NF +E + P KA + ++ Sbjct: 337 FFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEE----DKGEEETFPIPKAFVGNQ- 391 Query: 362 LSFVGYTY 385 L FVG+TY Sbjct: 392 LPFVGFTY 399
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/128 (35%), Positives = 74/128 (57%), Gaps = 2/128 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI++ +N + FPDD+ +S EA++LIC L D + R+G G ++IK H Sbjct: 277 PFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHL 336 Query: 188 WFRG--VAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ AW+ L + A P ++ ++DT NF +E + P KA + ++ Sbjct: 337 FFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEE----DKGDEETFPIPKAFVGNQ- 391 Query: 362 LSFVGYTY 385 L FVG+TY Sbjct: 392 LPFVGFTY 399
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 80.5 bits (197), Expect = 3e-15 Identities = 46/128 (35%), Positives = 74/128 (57%), Gaps = 2/128 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI++ +N + FPDD+ +S EA++LIC L D + R+G G ++IK H Sbjct: 277 PFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHL 336 Query: 188 WFRG--VAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ AW+ L + A P ++ ++DT NF +E + P KA + ++ Sbjct: 337 FFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEE----DKGDEETFPIPKAFVGNQ- 391 Query: 362 LSFVGYTY 385 L FVG+TY Sbjct: 392 LPFVGFTY 399
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 78.2 bits (191), Expect = 2e-14 Identities = 43/128 (33%), Positives = 76/128 (59%), Gaps = 2/128 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI+ +N + FP+D+ +S A++LIC L D + R+G G ++IK HP Sbjct: 293 PFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKQHP 352 Query: 188 WFRGVA--WDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ WD + E A P+++ ++D+ N FD++++ + P KA + ++ Sbjct: 353 FFKNDQWNWDNIRETAAPVVPELSSDIDSSN---FDDIEDD-KGDVETFPIPKAFVGNQ- 407 Query: 362 LSFVGYTY 385 L F+G+TY Sbjct: 408 LPFIGFTY 415
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 78.2 bits (191), Expect = 2e-14 Identities = 43/128 (33%), Positives = 76/128 (59%), Gaps = 2/128 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI+ +N + FP+D+ +S A++LIC L D + R+G G ++IK HP Sbjct: 293 PFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHP 352 Query: 188 WFRGVA--WDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ WD + E A P+++ ++D+ N FD++++ + P KA + ++ Sbjct: 353 FFKNDQWNWDNIRETAAPVVPELSSDIDSSN---FDDIEDD-KGDVETFPIPKAFVGNQ- 407 Query: 362 LSFVGYTY 385 L F+G+TY Sbjct: 408 LPFIGFTY 415
>LATS1_HUMAN (O95835) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) Length = 1130 Score = 77.4 bits (189), Expect = 3e-14 Identities = 36/96 (37%), Positives = 58/96 (60%), Gaps = 1/96 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + P+ T K+++W+ + P ++LSPEA DLI +L + R+G GAD+IKAH Sbjct: 948 PPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAH 1007 Query: 185 PWFRGVAWDK-LYEMEAAFKPQVNDELDTQNFMKFD 289 P+F+ + + L + A++ P++ DT NF D Sbjct: 1008 PFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVD 1043
>DMPK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 639 Score = 77.4 bits (189), Expect = 3e-14 Identities = 48/132 (36%), Positives = 64/132 (48%), Gaps = 6/132 (4%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFP-DDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY+D T KIVH++ H+ P D + EARD I RLLC + R+G GA + H Sbjct: 287 PFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTH 346 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPS-----RKAKL 349 P+F G+ WD L + F P DT N FD +++ A G R+ Sbjct: 347 PFFFGLDWDGLRDSVPPFTPDFEGATDTCN---FDLVEDGLTAMVSGGGETLSDIREGAP 403 Query: 350 NSKDLSFVGYTY 385 L FVGY+Y Sbjct: 404 LGVHLPFVGYSY 415
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 77.0 bits (188), Expect = 4e-14 Identities = 42/128 (32%), Positives = 76/128 (59%), Gaps = 2/128 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI+ +N + FP+D+ +S A++LIC L D + R+G G ++I+ HP Sbjct: 293 PFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHP 352 Query: 188 WFRGVA--WDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ WD + E A P+++ ++D+ N FD++++ + P KA + ++ Sbjct: 353 FFKNDQWHWDNIRETAAPVVPELSSDIDSSN---FDDIEDD-KGDVETFPIPKAFVGNQ- 407 Query: 362 LSFVGYTY 385 L F+G+TY Sbjct: 408 LPFIGFTY 415
>LATS1_MOUSE (Q8BYR2) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) Length = 1129 Score = 75.9 bits (185), Expect = 8e-14 Identities = 36/96 (37%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + P+ T K++ W+ + P ++LSPEA DLI +L + R+G GAD+IKAH Sbjct: 947 PPFLAQTPLETQMKVIIWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAH 1006 Query: 185 PWFRGVAWDK-LYEMEAAFKPQVNDELDTQNFMKFD 289 P+F+ + + L + A++ P++ DT NF D Sbjct: 1007 PFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVD 1042
>DMPK_MOUSE (P54265) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 631 Score = 74.7 bits (182), Expect = 2e-13 Identities = 46/132 (34%), Positives = 65/132 (49%), Gaps = 6/132 (4%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFP-DDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY+D T KIVH+R H+ P D+ + EA+DLI LLC + R+G GA + H Sbjct: 277 PFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKH 336 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSK-- 358 P+F G+ W+ L + F P DT N FD +++ A G + + Sbjct: 337 PFFFGLDWEGLRDSVPPFTPDFEGATDTCN---FDVVEDRLTAMVSGGGETLSDMQEDMP 393 Query: 359 ---DLSFVGYTY 385 L FVGY+Y Sbjct: 394 LGVRLPFVGYSY 405
>MRCKB_MOUSE (Q7TT50) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/152 (30%), Positives = 77/152 (50%), Gaps = 4/152 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDD-SRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY++ + T KI++ +FP + +S EA+DLI RL+C + R+G G + K H Sbjct: 280 PFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKH 339 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDL 364 +F G+ W+ + +EA + P V+ DT NF D+M + P + L Sbjct: 340 AFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDMLRNIEI---LPPGSHTGFSGLHL 396 Query: 365 SFVGYTYKN---FDAVKGLKHADMQRSSSLTR 451 F+G+T+ F LK M +S++LT+ Sbjct: 397 PFIGFTFTTESCFSDRGSLK--SMTQSNTLTK 426
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 72.8 bits (177), Expect = 7e-13 Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDD-SRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY++ + T KI++ +FP + +S EA+DLI RL+C + R+G G + K H Sbjct: 280 PFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKH 339 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDL 364 +F G+ W+ + +EA + P V+ DT NF D++ + P + L Sbjct: 340 AFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNTEI---LPPGSHTGFSGLHL 396 Query: 365 SFVGYTY 385 F+G+T+ Sbjct: 397 PFIGFTF 403
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 72.0 bits (175), Expect = 1e-12 Identities = 41/128 (32%), Positives = 75/128 (58%), Gaps = 2/128 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PFY+D + T KI+ +N + FP+D+ +S A++LIC L D + R+G G ++IK+ Sbjct: 284 PFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFLTDREVRLGRNGVEEIKSAS 343 Query: 188 WFRGVA--WDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD 361 +F+ WD + E A P+++ ++D+ N FD++++ + P KA + ++ Sbjct: 344 FFKNDQWNWDNIRETAAPVVPELSSDIDSSN---FDDIEDD-KGDVETFPIPKAFVGNQ- 398 Query: 362 LSFVGYTY 385 L F+G+TY Sbjct: 399 LPFIGFTY 406
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/127 (30%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDD-SRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PFY++ + T KI++ +FP + +S EA+DLI RL+C + R+G G + K H Sbjct: 280 PFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKH 339 Query: 185 PWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDL 364 +F G+ W+ + +EA + P V+ DT NF D++ + P + L Sbjct: 340 AFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNIEI---LPPGSHTGFSGLHL 396 Query: 365 SFVGYTY 385 F+G+T+ Sbjct: 397 PFIGFTF 403
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 69.7 bits (169), Expect = 6e-12 Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 6/98 (6%) Frame = +2 Query: 2 YPPFYSDDPITTCRKI----VHWRNHVKFPDDSR-LSPEARDLICRLLC-DVDHRIGGAG 163 YPPF+++ P +KI + W ++ L+PEA+DLI +LL D R+G G Sbjct: 1185 YPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKG 1244 Query: 164 ADQIKAHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 +IK HP+F+ V WD +Y+ EA+F P +++ DT F Sbjct: 1245 IQEIKDHPYFKNVDWDHVYDEEASFVPTIDNPEDTDYF 1282
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 69.7 bits (169), Expect = 6e-12 Identities = 48/134 (35%), Positives = 69/134 (51%), Gaps = 7/134 (5%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQIKA 181 PPFYS + T +KI++ +K P + +SPEA+ L+ LL +VD R+G G ++K Sbjct: 348 PPFYSQNVSTMYQKILN--GELKIP--TYISPEAKSLLEGLLTREVDKRLGTKGGGEVKQ 403 Query: 182 HPWFRGVAWDKL--YEMEAAFKPQVNDELDTQN----FMKFDEMDNSPPARRGSGPSRKA 343 HPWF+ + W+KL E+E FKP+V D F + MD+ S Sbjct: 404 HPWFKNIDWEKLDRKEVEVHFKPKVKSGTDISQIDPVFTQERPMDSLVET------SALG 457 Query: 344 KLNSKDLSFVGYTY 385 KD SF G+TY Sbjct: 458 DAMGKDTSFEGFTY 471
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 62.8 bits (151), Expect = 7e-10 Identities = 40/104 (38%), Positives = 54/104 (51%), Gaps = 5/104 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G Sbjct: 282 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 337 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMD 298 IK H WF W +Y+ +EA F P+ DT NF ++E D Sbjct: 338 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEED 381
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 62.8 bits (151), Expect = 7e-10 Identities = 40/104 (38%), Positives = 54/104 (51%), Gaps = 5/104 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMD 298 IK H WF W +Y+ +EA F P+ DT NF ++E D Sbjct: 291 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEED 334
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 62.8 bits (151), Expect = 7e-10 Identities = 40/104 (38%), Positives = 54/104 (51%), Gaps = 5/104 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMD 298 IK H WF W +Y+ +EA F P+ DT NF ++E D Sbjct: 291 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEED 334
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 62.8 bits (151), Expect = 7e-10 Identities = 40/104 (38%), Positives = 54/104 (51%), Gaps = 5/104 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMD 298 IK H WF W +Y+ +EA F P+ DT NF ++E D Sbjct: 291 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEED 334
>CEK1_SCHPO (P38938) Serine/threonine-protein kinase cek1 (EC 2.7.11.1)| Length = 1338 Score = 62.4 bits (150), Expect = 9e-10 Identities = 49/170 (28%), Positives = 73/170 (42%), Gaps = 26/170 (15%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQIK 178 YPPF ++ P + I+ R + + S A DLI RLLC + +R+G G ++IK Sbjct: 894 YPPFNAETPDQVFQNILARRINWPAEVFTAESSVALDLIDRLLCMNPANRLGANGVEEIK 953 Query: 179 AHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF-------MKFDEMDNSPPARRGS---- 325 AHP+F+ V WD + E + F P+ DT F F E N P Sbjct: 954 AHPFFKSVNWDTILEEDPPFVPKPFSPEDTVYFDSRGLKGFDFSEYYNQPTVTEAQKLEE 1013 Query: 326 -----------GPSRKAKLNSKDLS---FVGYTYKNFDAVKGLKHADMQR 433 +RK +L S +S F +TY+N D + +Q+ Sbjct: 1014 ERPASSIPQHVSGNRKGRLRSNTISTPEFGSFTYRNLDFLNKANRNTIQK 1063
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 62.4 bits (150), Expect = 9e-10 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 9/111 (8%) Frame = +2 Query: 2 YPPFYSDDPITTCRKI----VHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA-- 160 YPPFY + P KI + W H + P A+DLI +LL D R+G Sbjct: 466 YPPFYDEQPFGIYEKILSGKIEWERH--------MDPIAKDLIKKLLVNDRTKRLGNMKN 517 Query: 161 GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDEMDNSP 307 GAD +K H WF+ + W+ +Y +++ P V+ + DT+NF + E D P Sbjct: 518 GADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKP 568
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 62.0 bits (149), Expect = 1e-09 Identities = 41/111 (36%), Positives = 57/111 (51%), Gaps = 7/111 (6%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPFY DD KI+ R + FP +A+DLI RLL D R+G GA Sbjct: 528 YPPFYDDDTFAIYNKILAGR--ITFP--LGFDVDAKDLIKRLLTADRTRRLGALKDGALD 583 Query: 173 IKAHPWFRGVAWDKLYEM--EAAFKPQVNDELDTQNFMKFD--EMDNSPPA 313 +K H WF + W++LY+ F P++ + D+ NF +D EM PP+ Sbjct: 584 VKNHRWFSDINWERLYQRRDNGPFIPKIQHQGDSSNFEMYDEEEMVEEPPS 634
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEE 332
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEE 332
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 61.2 bits (147), Expect = 2e-09 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSD 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEE 332
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/94 (37%), Positives = 56/94 (59%), Gaps = 3/94 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDV-DHRIGGAGADQIKA 181 PPFY ++ RKI+ ++ ++FPD+ + +A+DL+ LL + R+G GA +IK Sbjct: 426 PPFYDENINEMYRKIL--QDPLRFPDN--IDEKAKDLLSGLLTRAPEKRLGSGGAQEIKN 481 Query: 182 HPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNF 277 HP+F + W KL +++ FKP V +DT NF Sbjct: 482 HPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNF 515
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 234 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 289 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 290 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 331
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 40/102 (39%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 +PPFY+D PI KIV R V+FP S+LS + + L+ LL D+ R G G Sbjct: 235 FPPFYADQPIQIYEKIVSGR--VRFP--SKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGD 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF +W +YE +EA F P+ D NF ++E Sbjct: 291 IKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEE 332
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 332
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 332
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 332
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 332
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 332
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 332
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 60.5 bits (145), Expect = 3e-09 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + V+FP S S + +DL+ LL D+ R G G + Sbjct: 235 YPPFFADQPIQIYEKIVSGK--VRFP--SHFSSDLKDLLRNLLQVDLTKRFGNLKNGVND 290 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK H WF W +Y+ +EA F P+ DT NF ++E Sbjct: 291 IKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 332
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/134 (26%), Positives = 61/134 (45%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PF T I++++ +KFPDD ++S + DLI LLC R+ G + HP Sbjct: 302 PFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKERLKFEG---LCCHP 358 Query: 188 WFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLS 367 +F + W+ + F P + + DT N FDE + + + + ++L Sbjct: 359 FFSKIDWNNIRNSPPPFVPTLKSDDDTSN---FDEPEKNSWVSSSPCQLSPSGFSGEELP 415 Query: 368 FVGYTYKNFDAVKG 409 FVG++Y + G Sbjct: 416 FVGFSYSKALGILG 429
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 57.8 bits (138), Expect = 2e-08 Identities = 48/152 (31%), Positives = 75/152 (49%), Gaps = 12/152 (7%) Frame = +2 Query: 77 PDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKL--YEMEAAFK 241 P R+ P A+DL+ RLLC D R+G GA +++ HP+F+G+ W L ++ A F+ Sbjct: 260 PFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFR 319 Query: 242 PQVNDELDTQNFM-KFDEMD--NSPPARRGSGPSRKAKLNSKDLSFVGYTYKN----FDA 400 PQ+ ELD NF +F ++ SPP GS P ++ F GY++ FD Sbjct: 320 PQIRSELDVGNFAEEFTRLEPVYSPP---GSPPPGDPRI------FQGYSFVAPSILFDH 370 Query: 401 VKGLKHADMQRSSSLTRPSIGAIFGSNGMESS 496 + ++ + RP A+ S M+ S Sbjct: 371 NNAVMTDGLEAPGAGDRPGRAAVARSAMMQDS 402
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 57.4 bits (137), Expect = 3e-08 Identities = 49/140 (35%), Positives = 70/140 (50%), Gaps = 6/140 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAG-ADQI 175 + PFY+D+ + IV + V+FP LS EARDLI LL + HR+G G +++ Sbjct: 465 WSPFYADNTQQLYKNIVFGK--VRFPR-GLLSVEARDLIKLLLNRNPKHRLGAHGDVEEV 521 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNF-MKFDEMDNSPPARRGSGPSRKAK 346 HP+F G+ W KL E+ FKP V E+D NF ++F S A Sbjct: 522 MKHPFFDGIDWKKLAAKEISPPFKPIVEGEIDVSNFDVEFTNKAIDRDFSSTDEMSTSAP 581 Query: 347 LNSK-DLSFVGYTYKNFDAV 403 L+S F G+TY + A+ Sbjct: 582 LSSTVQNGFKGFTYIDASAM 601
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 57.4 bits (137), Expect = 3e-08 Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 11/151 (7%) Frame = +2 Query: 77 PDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKL--YEMEAAFK 241 P R+ P A+DL+ RLLC D R+G GA ++K+HP+F+G+ W L ++ A F+ Sbjct: 260 PFPLRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVKSHPFFQGLDWWALAARKIPAPFR 319 Query: 242 PQVNDELDTQNFMKFDEMDNSPP--ARRGSGPSRKAKLNSKDLSFVGYTYKN----FDAV 403 PQ+ ELD NF +E P + GS P ++ F GY++ FD Sbjct: 320 PQIRSELDVGNFA--EEFTRLEPVYSPAGSPPPGDPRI------FQGYSFVAPSILFDHN 371 Query: 404 KGLKHADMQRSSSLTRPSIGAIFGSNGMESS 496 + +Q + RP A+ S M+ S Sbjct: 372 NAVMADVLQAPGAGYRPGRAAVARSAMMQDS 402
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 57.0 bits (136), Expect = 4e-08 Identities = 43/138 (31%), Positives = 71/138 (51%), Gaps = 7/138 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQ 172 +PPF+ D+P +KI+ + + FP +L ++DLI +LL D R+G GA+ Sbjct: 238 FPPFFDDNPFGIYQKILACK--IDFP--RQLDFTSKDLIKKLLVVDRTRRLGNMKNGAED 293 Query: 173 IKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKF--DEMDNSPPARRGSGPSRK 340 IK H WFRGV W+ + +++ P+++ + D NF + E+D +P Sbjct: 294 IKRHRWFRGVEWESVPQRKLKPPIVPKLSGDGDISNFETYPESELDKTP----------- 342 Query: 341 AKLNSKDLSFVGYTYKNF 394 ++ KDL T+KNF Sbjct: 343 -SVSDKDLE----TFKNF 355
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 57.0 bits (136), Expect = 4e-08 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 3/94 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQIKA 181 PP+Y ++ +KI+ + + FPD P A+DL+ LL D R+G G D+I+ Sbjct: 540 PPYYDENVPVMYKKIL--QQPLLFPDG--FDPAAKDLLIGLLSRDPSRRLGVNGTDEIRN 595 Query: 182 HPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 HP+F+ ++W KL +KP V E+DT NF Sbjct: 596 HPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANF 629
>CTRO_MOUSE (P49025) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2055 Score = 57.0 bits (136), Expect = 4e-08 Identities = 35/126 (27%), Positives = 58/126 (46%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAHP 187 PF T I++++ +KFPDD ++S E DL+ LLC R+ G + HP Sbjct: 301 PFTEGTSARTFNNIMNFQRFLKFPDDPKVSSELLDLLQSLLCVQKERLKFEG---LCCHP 357 Query: 188 WFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLS 367 +F W+ + F P + + DT N FDE + + + + ++L Sbjct: 358 FFARTDWNNIRNSPPPFVPTLKSDDDTSN---FDEPEKNSWVSSSVCQLSPSGFSGEELP 414 Query: 368 FVGYTY 385 FVG++Y Sbjct: 415 FVGFSY 420
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 56.6 bits (135), Expect = 5e-08 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 6/105 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQ 172 Y PFY + + T KI++ ++FP + + +DL+ RL+ D+ R+G G + Sbjct: 279 YTPFYDSNTMKTYEKILN--AELRFPPF--FNEDVKDLLSRLITRDLSQRLGNLQNGTED 334 Query: 173 IKAHPWFRGVAWDKLY--EMEAAFKPQVND-ELDTQNFMKFDEMD 298 +K HPWF+ V W+KL +E ++P + + DT F K+ E D Sbjct: 335 VKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEED 379
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 56.6 bits (135), Expect = 5e-08 Identities = 37/102 (36%), Positives = 53/102 (51%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGG--AGADQ 172 YPPF++D PI KIV + V+FP S + +DL+ LL D+ R G AG + Sbjct: 237 YPPFFADQPIQIYEKIVSGK--VRFP--SHFGSDLKDLLRNLLQVDLTKRYGNLKAGVND 292 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDE 292 IK WF W +++ +EA F P+ DT NF ++E Sbjct: 293 IKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEE 334
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 55.8 bits (133), Expect = 9e-08 Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 6/109 (5%) Frame = +2 Query: 77 PDDSRLSPEARDLICRLLCDVDHRIGGAG---ADQIKAHPWFRGVAWDKL--YEMEAAFK 241 P +S ++D+I RLL + G G AD+IK HP+F+ + WD L ++ A FK Sbjct: 267 PYPQEMSALSKDIIQRLLMKDPKKRLGCGPTDADEIKQHPFFQNINWDDLAAKKVPAPFK 326 Query: 242 PQVNDELDTQNFM-KFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTY 385 P + DELD NF +F EMD P + P K+ F GY++ Sbjct: 327 PVIRDELDVSNFAEEFTEMD--PTYSPAATPQTSEKI------FQGYSF 367
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 6/103 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGG--AGADQ 172 Y PFY P+ T KI+ + V +P P+ DL+ +L+ D+ RIG +G+ Sbjct: 262 YTPFYDTTPMKTYEKILQGK--VVYPP--YFHPDVVDLLSKLITADLTRRIGNLQSGSRD 317 Query: 173 IKAHPWFRGVAWDKLY--EMEAAFKPQVNDEL-DTQNFMKFDE 292 IKAHPWF V W++L ++E ++P + + DT F ++ E Sbjct: 318 IKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPE 360
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/94 (35%), Positives = 53/94 (56%), Gaps = 3/94 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQIKA 181 PP+Y +D +KI+ + + FPD +A+DL+ LL D R+G GAD+I+ Sbjct: 543 PPYYDEDVPKMYKKIL--QEPLVFPDG--FDRDAKDLLIGLLSRDPTRRLGYNGADEIRN 598 Query: 182 HPWFRGVAWDKLYEME--AAFKPQVNDELDTQNF 277 HP+F ++W +L +KP V++ +DT NF Sbjct: 599 HPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNF 632
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 53.9 bits (128), Expect = 3e-07 Identities = 33/103 (32%), Positives = 57/103 (55%), Gaps = 6/103 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQ 172 Y PFY+ + + T I++ +KFP P+A+DL+ +L+ D+ R+G G++ Sbjct: 280 YTPFYNSNTMKTYENILN--AELKFPPF--FHPDAQDLLKKLITRDLSERLGNLQNGSED 335 Query: 173 IKAHPWFRGVAWDKLYE--MEAAFKPQVND-ELDTQNFMKFDE 292 +K HPWF V W+KL +E ++P + + DT F ++ E Sbjct: 336 VKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPE 378
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 53.9 bits (128), Expect = 3e-07 Identities = 31/92 (33%), Positives = 50/92 (54%), Gaps = 2/92 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLLCDVD-HRIGGAGADQIKA 181 PF+ D P +++ + + +P+ D L P+A+DL +LL R+G + A ++K Sbjct: 665 PFFGDTPEELFGQVIS--DEIVWPEGDDALPPDAQDLTSKLLHQNPLERLGTSSAYEVKQ 722 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 HP+F G+ W L +A F PQ+ E DT F Sbjct: 723 HPFFMGLDWTGLLRQKAEFIPQLESEDDTSYF 754
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 53.5 bits (127), Expect = 4e-07 Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 2/92 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLLCDVD-HRIGGAGADQIKA 181 PF+ D P +++ + + +P+ D L P+A+DL +LL R+G A ++K Sbjct: 724 PFFGDTPEELFGQVIS--DEIVWPEGDEALPPDAQDLTSKLLHQNPLERLGTGSAYEVKQ 781 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 HP+F G+ W L +A F PQ+ E DT F Sbjct: 782 HPFFTGLDWTGLLRQKAEFIPQLESEDDTSYF 813
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 5/113 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCD-VDHRIGGA--GADQI 175 PPF DP+ T I+ + ++FP +++ A +LI +L D R+G G I Sbjct: 555 PPFSGPDPMKTYNIILRGIDMIEFP--KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDI 612 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSG 328 + H WF G W+ L + + P V DT NF F E ++ PP SG Sbjct: 613 QKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 665
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 5/113 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCD-VDHRIGGA--GADQI 175 PPF DP+ T I+ + ++FP +++ A +LI +L D R+G G I Sbjct: 555 PPFSGPDPMKTYNIILRGIDMIEFP--KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDI 612 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSG 328 + H WF G W+ L + + P V DT NF F E ++ PP SG Sbjct: 613 QKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 665
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 5/113 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCD-VDHRIGGA--GADQI 175 PPF DP+ T I+ + ++FP +++ A +LI +L D R+G G I Sbjct: 571 PPFSGPDPMKTYNIILRGIDMIEFP--KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDI 628 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSG 328 + H WF G W+ L + + P V DT NF F E ++ PP SG Sbjct: 629 QKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 681
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 5/113 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCD-VDHRIGGA--GADQI 175 PPF DP+ T I+ + ++FP +++ A +LI +L D R+G G I Sbjct: 571 PPFSGPDPMKTYNIILRGIDMIEFP--KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDI 628 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSG 328 + H WF G W+ L + + P V DT NF F E ++ PP SG Sbjct: 629 QKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSG 681
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 53.1 bits (126), Expect = 6e-07 Identities = 41/109 (37%), Positives = 55/109 (50%), Gaps = 6/109 (5%) Frame = +2 Query: 77 PDDSRLSPEARDLICRLLCDVDHRIGGAG---ADQIKAHPWFRGVAWDKLY--EMEAAFK 241 P +S A+DLI RLL + G G AD+IK H +F+ + WD L ++ A FK Sbjct: 277 PYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFK 336 Query: 242 PQVNDELDTQNFM-KFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTY 385 P + DELD NF +F EMD P + P KL F GY++ Sbjct: 337 PVIRDELDVSNFAEEFTEMD--PTYSPAALPQSSEKL------FQGYSF 377
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 53.1 bits (126), Expect = 6e-07 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCD-VDHRIGGA--GADQI 175 PPF DP+ T I+ + ++FP +++ A +LI +L D R+G G I Sbjct: 571 PPFSGPDPMKTYNIILRGIDMIEFP--KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDI 628 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSG 328 + H WF G W+ L + + P V DT NF F E + PP SG Sbjct: 629 QKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSG 681
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 52.8 bits (125), Expect = 7e-07 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 5/104 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQ 172 +PPF+ D+P +KI+ + + FP L +DLI +LL D R+G GA+ Sbjct: 241 FPPFFDDNPFGIYQKILAGK--IDFP--RHLDFHVKDLIKKLLVVDRTRRLGNMKNGAND 296 Query: 173 IKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMD 298 +K H WFR V W+ + +++ P++ + DT NF + E D Sbjct: 297 VKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYPEND 340
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 52.8 bits (125), Expect = 7e-07 Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 5/113 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCD-VDHRIGGA--GADQI 175 PPF DP+ T I+ + ++FP +++ A +LI +L D R+G G I Sbjct: 555 PPFSGPDPMKTYNIILRGIDMIEFP--KKIAKNAANLIKKLCRDNPSERLGNLKNGVKDI 612 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSG 328 + H WF G W+ L + + P V DT NF F E ++ PP SG Sbjct: 613 QKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDGFPEDNDEPPPDDNSG 665
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP L PEA+ L+ LL D R+GG D +I Sbjct: 348 PFYNQDHEKLFELIL--MEEIRFP--RTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIM 403 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 H +F G+ W +YE + FKPQV E DT+ F Sbjct: 404 QHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYF 438
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 5/88 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQ 172 YPPFYS++P+ I+ + V +P S SP + DL+ LL D+ R G G+ Sbjct: 394 YPPFYSENPMKLYENILEGK--VNYP--SYFSPASIDLLSHLLQRDITCRYGNLKDGSMD 449 Query: 173 IKAHPWFRGVAWDKLY--EMEAAFKPQV 250 I HPWFR ++WDK+ ++E + P + Sbjct: 450 IIMHPWFRDISWDKILTRKIEVPYVPPI 477
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 52.0 bits (123), Expect = 1e-06 Identities = 38/113 (33%), Positives = 53/113 (46%), Gaps = 19/113 (16%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 YPPF++D PI KIV + VKFP S S E +DL+ LL D+ R G G Sbjct: 273 YPPFFADQPIQIYEKIVSGK--VKFP--SHFSNELKDLLKNLLQVDLTKRYGNLKNGVAD 328 Query: 173 IKAHPWFRGVAWDKLYEME----------------AAFKPQVNDELDTQNFMK 283 IK H WF W +Y+ + A P+V+ DT++F++ Sbjct: 329 IKNHKWFGSTDWIAIYQKKITPPSFSKGESNGRLFEALYPRVDGPADTRHFVE 381
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLLCDVD-HRIGGAGADQIKA 181 PF+ D P ++V + + +P+ D L +A+DLI RLL R+G G ++K Sbjct: 579 PFFGDTPEELFGQVVS--DEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQ 636 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 HP+F + W L +A F PQ+ E DT F Sbjct: 637 HPFFLALDWAGLLRHKAEFVPQLEAEDDTSYF 668
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP LSPEA+ L+ LL D R+GG D +I Sbjct: 348 PFYNQDHEKLFELIL--MEEIRFP--RTLSPEAKSLLSGLLKKDPKQRLGGGSEDAKEIM 403 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 H +F + W +YE + FKPQV E DT+ F Sbjct: 404 QHRFFASIVWQDVYEKKLSPPFKPQVTSETDTRYF 438
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 51.2 bits (121), Expect = 2e-06 Identities = 40/109 (36%), Positives = 54/109 (49%), Gaps = 6/109 (5%) Frame = +2 Query: 77 PDDSRLSPEARDLICRLLCDVDHRIGGAG---ADQIKAHPWFRGVAWDKLY--EMEAAFK 241 P +S A+DLI LL + G G AD+IK H +F+ + WD L ++ A FK Sbjct: 277 PYPQEMSALAKDLIQHLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFK 336 Query: 242 PQVNDELDTQNFM-KFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTY 385 P + DELD NF +F EMD P + P KL F GY++ Sbjct: 337 PVIRDELDVSNFAEEFTEMD--PTYSPAALPQSSEKL------FQGYSF 377
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 50.8 bits (120), Expect = 3e-06 Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QI 175 PPF +++ T KI+ R + P L+P+ARDL+ + L + RIGG D + Sbjct: 267 PPFTAENRKKTMDKII--RGKLALPP--YLTPDARDLVKKFLKRNPSQRIGGGPGDAADV 322 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 + HP+FR + WD L + ++ F+P + E D F P P A Sbjct: 323 QRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQF--DTRFTRQTPV---DSPDDTALS 377 Query: 350 NSKDLSFVGYTY 385 S + +F+G+TY Sbjct: 378 ESANQAFLGFTY 389
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 50.4 bits (119), Expect = 4e-06 Identities = 35/98 (35%), Positives = 52/98 (53%), Gaps = 4/98 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGG-AGADQI 175 + PFY+ D R I + V+FP LS E R + LL + +HR+G A ++ Sbjct: 501 WSPFYAPDVQQMYRNIAFGK--VRFPKGV-LSSEGRSFVRGLLNRNPNHRLGAVADTTEL 557 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMK 283 K HP+F + WD L + ++ FKP V ++LD NF K Sbjct: 558 KEHPFFADINWDLLSKKKVQPPFKPNVQNDLDVSNFDK 595
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 50.4 bits (119), Expect = 4e-06 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP L PEA+ L+ LL D R+GG D +I Sbjct: 349 PFYNQDHEKLFELIL--MEEIRFP--RTLLPEAKSLLSGLLKKDPKQRLGGGPDDAKEIM 404 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 H +F G+ W +YE + FKPQV E DT+ F Sbjct: 405 QHKFFAGIVWQDVYEKKLVPPFKPQVTSETDTRYF 439
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 6/80 (7%) Frame = +2 Query: 77 PDDSRLSPEARDLICRLLCDVDHRIGGAG---ADQIKAHPWFRGVAWDKLY--EMEAAFK 241 P +S A+DL+ RLL + G G A++IK H +F + WD L ++ A FK Sbjct: 276 PYPQEMSTVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKWDDLAAKKVPAPFK 335 Query: 242 PQVNDELDTQNFM-KFDEMD 298 P + DELD NF +F EMD Sbjct: 336 PVIRDELDVSNFAEEFTEMD 355
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 50.1 bits (118), Expect = 5e-06 Identities = 34/95 (35%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP L PEA+ L+ LL D R+GG D +I Sbjct: 348 PFYNQDHEKLFELIL--MEEIRFP--RTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIM 403 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 H +F + W +YE + FKPQV E DT+ F Sbjct: 404 QHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYF 438
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 50.1 bits (118), Expect = 5e-06 Identities = 34/95 (35%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP L PEA+ L+ LL D R+GG D +I Sbjct: 369 PFYNQDHEKLFELIL--MEEIRFP--RTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIM 424 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 H +F + W +YE + FKPQV E DT+ F Sbjct: 425 QHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYF 459
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ + FP L PEA+ L+ LL D R+GG D +I Sbjct: 348 PFYNQDHEKLFELIL--MEEIAFP--RTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIM 403 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 H +F + W +YE + FKPQV E DT+ F Sbjct: 404 QHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYF 438
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ +KFP LS +A+ L+ LL D + R+GG D +I Sbjct: 345 PFYNQDHEKLFELIL--MEDIKFP--RTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIM 400 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 H +F GV W +Y+ + FKPQV E DT+ F Sbjct: 401 RHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYF 435
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ +KFP LS +A+ L+ LL D + R+GG D +I Sbjct: 345 PFYNQDHEKLFELIL--MEDIKFP--RTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIM 400 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 H +F GV W +Y+ + FKPQV E DT+ F Sbjct: 401 RHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYF 435
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ +KFP LS +A+ L+ LL D + R+GG D +I Sbjct: 345 PFYNQDHEKLFELIL--MEDIKFP--RTLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIM 400 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 H +F GV W +Y+ + FKPQV E DT+ F Sbjct: 401 RHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYF 435
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 8/123 (6%) Frame = +2 Query: 86 SRLSPEARDLICRLL-CDVDHRIGG--AGADQIKAHPWFRGVAWDKL--YEMEAAFKPQV 250 S S ARD + ++L + R+GG A +IK HP+F G+ W +L +A +KP + Sbjct: 492 SSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTL 551 Query: 251 NDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTY---KNFDAVKGLKHA 421 E D QNF + D P P + +L F GYTY ++ + ++ H Sbjct: 552 TAEDDVQNFSN-EFTDQVPEDPECDAPPSRIRL------FRGYTYVAPEHLEQMRRDNHC 604 Query: 422 DMQ 430 ++Q Sbjct: 605 EIQ 607
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/113 (33%), Positives = 59/113 (52%), Gaps = 8/113 (7%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ VKFP + ++ EA++L+ LL D R+GG D +I+ Sbjct: 463 PFYNRDHDVLFTLILV--EEVKFPRN--ITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQ 518 Query: 179 AHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMK---FDEMDNSPPARRG 322 AHP+F + W L ++ FKPQV + DT+ F K + ++ +PP G Sbjct: 519 AHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPDPTG 571
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 47.8 bits (112), Expect = 2e-05 Identities = 41/136 (30%), Positives = 56/136 (41%), Gaps = 8/136 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGA---DQIK 178 PF DD T R I + FP S EA D+I L + GAG +I Sbjct: 569 PFEGDDETTVFRNIKDKK--AVFP--KHFSVEAMDIITSFLTKKPNNRLGAGRYARQEIT 624 Query: 179 AHPWFRGVAWDK--LYEMEAAFKPQVNDELDTQNF---MKFDEMDNSPPARRGSGPSRKA 343 HP+FR V WDK EME KP + D NF ++ D +P + Sbjct: 625 THPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTP-------TDKLF 677 Query: 344 KLNSKDLSFVGYTYKN 391 +N F+G+++ N Sbjct: 678 MMNLDQNDFIGFSFMN 693
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 47.8 bits (112), Expect = 2e-05 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PPFY+ D RKI+ + FP +SP+AR L+ +LL D + R+ A + IK Sbjct: 317 PPFYNQDVQEMYRKIM--MEKLSFPHF--ISPDARSLLEQLLERDPEKRL--ADPNLIKR 370 Query: 182 HPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNS 355 HP+FR + W++L++ + F P V DT + P+ +G Sbjct: 371 HPFFRSIDWEQLFQKNIPPPFIPNVKGSADTSQIDPV--FTDEAPSLTMAGECALNPQQQ 428 Query: 356 KDLSFVGYTY 385 KD F G+TY Sbjct: 429 KD--FEGFTY 436
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 5/114 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVD-HRIG--GAGADQI 175 PPF DP+ T I+ + ++FP + ++ A +LI +L D R+G G +I Sbjct: 819 PPFTGSDPMRTYNIILKGIDAIEFPRN--ITRNASNLIKKLCRDNPAERLGYQRGGISEI 876 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGP 331 + H WF G W L +E KP V +DT NF D+ PP G P Sbjct: 877 QKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNF------DDYPPDPEGPPP 924
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 47.8 bits (112), Expect = 2e-05 Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 5/114 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVD-HRIG--GAGADQI 175 PPF DP+ T I+ + ++FP + ++ A +LI +L D R+G G +I Sbjct: 973 PPFTGSDPMRTYNIILKGIDAIEFPRN--ITRNASNLIKKLCRDNPAERLGYQRGGISEI 1030 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGP 331 + H WF G W L +E KP V +DT NF D+ PP G P Sbjct: 1031 QKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNF------DDYPPDPEGPPP 1078
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 47.4 bits (111), Expect = 3e-05 Identities = 36/137 (26%), Positives = 63/137 (45%), Gaps = 8/137 (5%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHR---IGGAGADQI 175 PPF +D I ++V +P LS EA++ L ++ G +G + + Sbjct: 547 PPFDGEDEEELFAAITD--HNVSYPKS--LSKEAKEACKGFLTKQPNKRLGCGSSGEEDV 602 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMK---FDEMDNSPPARRGSGPSRK 340 + HP+FR + W+K+ E++ FKP++ D NF K ++ D +P + Sbjct: 603 RLHPFFRRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTP-------TDKV 655 Query: 341 AKLNSKDLSFVGYTYKN 391 +N FVG++Y N Sbjct: 656 FMMNLDQSEFVGFSYMN 672
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 47.4 bits (111), Expect = 3e-05 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QI 175 PPF ++ T KI+ + ++ L+ EARDL+ +LL + R+G D ++ Sbjct: 291 PPFTGENRKKTIDKILKCKLNLP----PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEV 346 Query: 176 KAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AHP+FR + W++L ++E FKP + E D F + P P Sbjct: 347 QAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF--DSKFTRQTPV---DSPDDSTLS 401 Query: 350 NSKDLSFVGYTY 385 S + F+G+TY Sbjct: 402 ESANQVFLGFTY 413
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 47.4 bits (111), Expect = 3e-05 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QI 175 PPF ++ T KI+ + ++ L+ EARDL+ +LL + R+G D ++ Sbjct: 291 PPFTGENRKKTIDKILKCKLNLP----PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEV 346 Query: 176 KAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AHP+FR + W++L ++E FKP + E D F + P P Sbjct: 347 QAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF--DSKFTRQTPV---DSPDDSTLS 401 Query: 350 NSKDLSFVGYTY 385 S + F+G+TY Sbjct: 402 ESANQVFLGFTY 413
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 47.4 bits (111), Expect = 3e-05 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QI 175 PPF ++ T KI+ + ++ L+ EARDL+ +LL + R+G D ++ Sbjct: 291 PPFTGENRKKTIDKILKCKLNLP----PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEV 346 Query: 176 KAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AHP+FR + W++L ++E FKP + E D F + P P Sbjct: 347 QAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF--DSKFTRQTPV---DSPDDSTLS 401 Query: 350 NSKDLSFVGYTY 385 S + F+G+TY Sbjct: 402 ESANQVFLGFTY 413
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 47.4 bits (111), Expect = 3e-05 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QI 175 PPF ++ T KI+ + ++ L+ EARDL+ +LL + R+G D ++ Sbjct: 291 PPFTGENRKKTIDKILKCKLNLP----PYLTQEARDLLKKLLKRNAASRLGAGPGDAGEV 346 Query: 176 KAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AHP+FR + W++L ++E FKP + E D F + P P Sbjct: 347 QAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQF--DSKFTRQTPV---DSPDDSTLS 401 Query: 350 NSKDLSFVGYTY 385 S + F+G+TY Sbjct: 402 ESANQVFLGFTY 413
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 47.4 bits (111), Expect = 3e-05 Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 5/132 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QI 175 PPF +++ T KI+ + + P L+P+ARDL + L + RIGG D + Sbjct: 267 PPFTAENRKKTMDKII--KGKLVLPP--YLTPDARDLAKKFLKRNPTQRIGGGLGDAADV 322 Query: 176 KAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 + HP+FR + WD L ++ F+P + E D F P P A Sbjct: 323 QRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFDA--RFTRQTPV---DSPDDTALS 377 Query: 350 NSKDLSFVGYTY 385 S + +F+G+TY Sbjct: 378 ESANQAFLGFTY 389
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIK 178 PFY+ D I+ +FP LSPEA+ L+ LL D R+GG A ++ Sbjct: 353 PFYNQDHERLFELIL--MEETRFP--RTLSPEAKSLLAGLLKKDPKQRLGGGPDDAQEVM 408 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 +H +F + W + E + + FKPQV E+DT+ F Sbjct: 409 SHGFFASINWQDVTERKLSPPFKPQVTSEIDTRYF 443
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/95 (34%), Positives = 49/95 (51%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIK 178 PFY+ D I+ ++FP LSPEA+ L+ LL D R+GG A ++ Sbjct: 354 PFYNQDHERLFELIL--MEEIRFP--RTLSPEAKSLLAGLLKKDPKQRLGGGPNDAQEVM 409 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 +H +F + W + E + FKPQV E+DT+ F Sbjct: 410 SHRFFVSINWQDVTERKLTPPFKPQVTSEIDTRYF 444
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 47.4 bits (111), Expect = 3e-05 Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 5/120 (4%) Frame = +2 Query: 41 RKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGG--AGADQIKAHPWFRGVAWD 211 +KIV ++ +K P LS EA ++ LL + + R+G +GA++IK H WF+G+ W Sbjct: 340 QKIV--KDKIKLPQF--LSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWK 395 Query: 212 KL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTY 385 KL E+ +FKP+V+ NF K D S S PS K N F +TY Sbjct: 396 KLEAREVMPSFKPEVSGRQCIANFDKC-WTDMSVLDSPASSPSSDPKAN----PFTNFTY 450
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 47.0 bits (110), Expect = 4e-05 Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVD-HRIGG-AGADQIKA 181 PF D+ T I+ VKFP D +S +DLI +LL + R+G +GA IK Sbjct: 541 PFKGDNSNETFSNIL--TKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKR 598 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVND 256 HP+F+ V W L + P +ND Sbjct: 599 HPFFKKVQWSFLRNQDPPLIPALND 623
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 47.0 bits (110), Expect = 4e-05 Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 5/120 (4%) Frame = +2 Query: 41 RKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGG--AGADQIKAHPWFRGVAWD 211 +KIV ++ +K P LS EA L+ LL + + R+G +GA++IK H WF+ + W Sbjct: 346 QKIV--KDKIKLPQF--LSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWK 401 Query: 212 KL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTY 385 KL E++ +FKP V+ NF K D S S P+ AK N F +TY Sbjct: 402 KLEAREVQPSFKPAVSGRQCIANFDKC-WTDMSVLDSPASSPNSDAKAN----PFTNFTY 456
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 46.6 bits (109), Expect = 5e-05 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGA--GADQI 175 + PF D+ T I+ +N V FP+++ +S +DLI +LL + + G GA + Sbjct: 714 FTPFKGDNTNETFTNIL--KNEVSFPNNNEISRTCKDLIKKLLTKNESKRLGCKMGAADV 771 Query: 176 KAHPWFRGVAWDKLYEMEAAFKPQVNDE 259 K HP+F+ V W L E P ++++ Sbjct: 772 KKHPFFKKVQWSLLRNQEPPLIPVLSED 799
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 46.6 bits (109), Expect = 5e-05 Identities = 37/110 (33%), Positives = 52/110 (47%), Gaps = 5/110 (4%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G GA+++K HP+F + W+KLY E+ FKP V Sbjct: 285 LSNEAQSLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPPFKPSVTQ 344 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTYKNFDAVK 406 DT F + +P G PS A + SFV DA K Sbjct: 345 PDDTYYF-DTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPVLVEEDAKK 393
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 46.2 bits (108), Expect = 7e-05 Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP LSPEA+ L+ LL D R+GG +D ++ Sbjct: 349 PFYNQDHERLFELIL--MEEIRFP--RTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVM 404 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 H +F + W + + + FKPQV E+DT+ F Sbjct: 405 EHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYF 439
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 45.8 bits (107), Expect = 9e-05 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Frame = +2 Query: 59 RNHVKFPDDS---RLSPEARDLICRLLC-DVDHRIGG-AGADQIKAHPWFRGVAWDKLYE 223 R + FPD + ++S + LI +LL D + R+G AGA IK HP+FR W + Sbjct: 483 REDIPFPDHAGAPQISNLCKSLIRKLLIKDENRRLGARAGASDIKTHPFFRTTQWALIRH 542 Query: 224 MEAAFKPQVNDELDTQNFMKFDEMDN 301 M+ P +DT NF E ++ Sbjct: 543 MKPPIVPNQGRGIDTLNFRNVKESES 568
>DBF20_YEAST (P32328) Serine/threonine-protein kinase DBF20 (EC 2.7.11.1)| Length = 564 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/144 (26%), Positives = 67/144 (46%), Gaps = 8/144 (5%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFP--DDSR--LSPEARDLICRLLCDVDHRIGGAGAD 169 Y PF T + +W+ ++ P +D R S DLI RL+ D +R+ + Sbjct: 404 YTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIADPINRV--RSFE 461 Query: 170 QIKAHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNFMKF-DEMDNSPPA---RRGSGPSR 337 Q++ +F + ++ L F PQ++DE D F F +E D + A +R + S Sbjct: 462 QVRKMSYFAEINFETLRTSSPPFIPQLDDETDAGYFDDFTNEEDMAKYADVFKRQNKLSA 521 Query: 338 KAKLNSKDLSFVGYTYKNFDAVKG 409 ++ D VG+T+++ D +G Sbjct: 522 MVDDSAVDSKLVGFTFRHRDGKQG 545
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 4/96 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAG-ADQI 175 + PF++++ +KI + VKFP D LS E R + LL + HR+G ++ Sbjct: 608 WSPFFAENNQKMYQKIAFGK--VKFPRDV-LSQEGRSFVKGLLNRNPKHRLGAIDDGREL 664 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 +AHP+F + W+ L + + FKP + E DT NF Sbjct: 665 RAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNF 700
>MASTL_MOUSE (Q8C0P0) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 865 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 PPF + P + I+ + + +P+ + +LS A+ + LL D + AG ++K Sbjct: 762 PPFNDETPQQVFQNIL--KRDIPWPEGEEKLSDNAQSAMDMLLTIDDSK--RAGMRELKQ 817 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 HP F V W+ L F PQ +DE DT F Sbjct: 818 HPLFSEVDWENLQHQTMPFVPQPDDETDTSYF 849
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 2/92 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PF+ D P +++ + + +P+ D L EA+ LI LL + R+G GA ++K Sbjct: 586 PFFGDTPEELFGQVIS--DDILWPEGDEALPTEAQLLISSLLQTNPLVRLGAGGAFEVKQ 643 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 H +FR + W L +A F P + E DT F Sbjct: 644 HSFFRDLDWTGLLRQKAEFIPHLESEDDTSYF 675
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP L PEA+ L+ LL D R+GG +D ++ Sbjct: 349 PFYNQDHERLFELIL--MEEIRFP--RTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVM 404 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 H +F + W + + + FKPQV E+DT+ F Sbjct: 405 EHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYF 439
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 44.7 bits (104), Expect = 2e-04 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGAD--QIK 178 PFY+ D I+ ++FP L PEA+ L+ LL D R+GG +D ++ Sbjct: 349 PFYNQDHERLFELIL--MEEIRFP--RTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVM 404 Query: 179 AHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNF 277 H +F + W + + + FKPQV E+DT+ F Sbjct: 405 EHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYF 439
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/127 (33%), Positives = 60/127 (47%), Gaps = 10/127 (7%) Frame = +2 Query: 29 ITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QIKAHPWFRG 199 ITTC +KFP+ RLSPEA L+ LL V + GAG D ++ +F+ Sbjct: 390 ITTC--------DLKFPN--RLSPEAVTLLSGLLERVPAKRLGAGPDDAREVSRAEFFKD 439 Query: 200 VAWDKLY--EMEAAFKPQVNDELDTQNF-MKFDEM--DNSPPARRGSGPS--RKAKLNSK 358 V W+ E+E FKP V E DT F +F M +PP R P+ + +L + Sbjct: 440 VDWEATLRKEVEPPFKPNVMSETDTSFFDREFTSMPVQLTPPRRGEELPTVDEEEELQAN 499 Query: 359 DLSFVGY 379 + F Y Sbjct: 500 FIQFASY 506
>MASTL_HUMAN (Q96GX5) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 879 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 PPF + P + I+ + + +P+ + +LS A+ + LL D + AG ++K Sbjct: 776 PPFNDETPQQVFQNIL--KRDIPWPEGEEKLSDNAQSAVEILLTIDDTK--RAGMKELKR 831 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 HP F V W+ L F PQ +DE DT F Sbjct: 832 HPLFSDVDWENLQHQTMPFIPQPDDETDTSYF 863
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 44.3 bits (103), Expect = 3e-04 Identities = 38/110 (34%), Positives = 52/110 (47%), Gaps = 5/110 (4%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G A GA++IK P+F + W+KL+ EM FKP V Sbjct: 285 LSNEAQSLLRALFKRNPTNRLGSAMEGAEEIKRQPFFSTIDWNKLFRREMSPPFKPAVTQ 344 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTYKNFDAVK 406 DT F + +P G PS A + SFV DA K Sbjct: 345 ADDTYYF-DTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPALVEEDAKK 393
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PF+ D P +++ + + +P+ D L +A+ LI LL + R+G GA ++K Sbjct: 587 PFFGDTPEELFGQVIS--DDILWPEGDEALPTDAQLLISSLLQTNPLVRLGAGGAFEVKQ 644 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 H +FR + W L +A F P + E DT F Sbjct: 645 HSFFRDLDWTGLLRQKAEFIPHLESEDDTSYF 676
>KGP1_DROME (Q03042) cGMP-dependent protein kinase, isozyme 1 (EC 2.7.11.12)| (CGK) Length = 768 Score = 43.9 bits (102), Expect = 3e-04 Identities = 36/107 (33%), Positives = 47/107 (43%), Gaps = 5/107 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDV-DHRIG--GAGADQI 175 PPF + DP+ T I+ + + FP +S A LI RL DV R+G G I Sbjct: 654 PPFSAPDPMQTYNLILKGIDMIAFP--KHISRWAVQLIKRLCRDVPSERLGYQTGGIQDI 711 Query: 176 KAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPP 310 K H WF G WD L + F + D + F +F N PP Sbjct: 712 KKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRFPCDLNEPP 758
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 43.9 bits (102), Expect = 3e-04 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPD-DSRLSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PF+ D P +++ + + +P+ D L +A+ LI LL + R+G GA ++K Sbjct: 588 PFFGDTPEELFGQVIS--DDILWPEGDEALPTDAQLLISSLLQTNPLVRLGAGGAFEVKQ 645 Query: 182 HPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 H +FR + W L +A F P + E DT F Sbjct: 646 HSFFRDLDWTGLLRQKAEFIPHLESEDDTSYF 677
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 43.5 bits (101), Expect = 4e-04 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 4/52 (7%) Frame = +2 Query: 134 DVDHRIGGA--GADQIKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 D + R+G A+++ AHP+F + WD LY E ++KP +ND D NF Sbjct: 902 DPNQRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKPLINDPRDLNNF 953
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 43.1 bits (100), Expect = 6e-04 Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 8/127 (6%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA---GADQ 172 PPF + + +KI+ + FP+ + P+ARDL+ +LL D R+G G Sbjct: 280 PPFRAGNEYLIFQKII--KLEYDFPE--KFFPKARDLVEKLLVLDATKRLGCEEMEGYGP 335 Query: 173 IKAHPWFRGVAWDKLYEME----AAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRK 340 +KAHP+F V W+ L++ A+ P ++++ D + +D + + + S S Sbjct: 336 LKAHPFFESVTWENLHQQTPPKLTAYLPAMSED-DEDCYGNYDNLLSQFGCMQVSSSSSS 394 Query: 341 AKLNSKD 361 L++ D Sbjct: 395 HSLSASD 401
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 42.7 bits (99), Expect = 8e-04 Identities = 37/136 (27%), Positives = 65/136 (47%), Gaps = 7/136 (5%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIG----GAGAD 169 PPF +D+ I++ + V +P LS EA +++ + + R+G G D Sbjct: 575 PPFEADNEDDLFEAILN--DDVLYP--VWLSKEAVNILKAFMTKNAGKRLGCVVSQGGED 630 Query: 170 QIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKA 343 I+AHP+FR + WD L +++ FKP++ + D NF + P S P+ Sbjct: 631 AIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNF--DSDFTKEEPVLTPSDPAVVR 688 Query: 344 KLNSKDLSFVGYTYKN 391 +N + F G+++ N Sbjct: 689 AINQDE--FRGFSFIN 702
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 42.7 bits (99), Expect = 8e-04 Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 8/105 (7%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA---GADQ 172 PPF + + +KI+ H FP+ + P+ARDL+ +LL D R+G G Sbjct: 283 PPFRAGNEYLIFQKIIKLEYH--FPE--KFFPKARDLVEKLLVLDATKRLGCEEMEGYGP 338 Query: 173 IKAHPWFRGVAWDKLYEME----AAFKPQVNDELDTQNFMKFDEM 295 +KAHP+F + W+ L++ A+ P ++++ D + +D + Sbjct: 339 LKAHPFFETITWENLHQQTPPKLTAYLPAMSED-DEDCYGNYDNL 382
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 42.7 bits (99), Expect = 8e-04 Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G GA++IK HP++ + W+KLY E++ FKP V Sbjct: 303 LSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQ 362 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFV 373 DT F + +P G PS A + SFV Sbjct: 363 PDDTFYF-DTEFTSRTPKDSPGIPPSAGAHQLFRGFSFV 400
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 4/104 (3%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDEL 262 L EA+DL+ +L + + R+G G I+ HP FR + W++L E++ F+P+V Sbjct: 602 LEKEAKDLLVKLFVREPEKRLGVRG--DIRQHPLFREINWEELERKEIDPPFRPKVKSPF 659 Query: 263 DTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLS-FVGYTYKN 391 D NF K E N P + +A +NS D + F +++ N Sbjct: 660 DCSNFDK--EFLNEKPRLSFAD---RALINSMDQNMFRNFSFMN 698
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/129 (26%), Positives = 62/129 (48%), Gaps = 8/129 (6%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA---GADQ 172 PPF + + +KI+ + FP+ + P+ARDL+ +LL D R+G G Sbjct: 283 PPFRAGNEYLIFQKII--KLEYDFPE--KFFPKARDLVEKLLVLDATKRLGCEEMEGYGP 338 Query: 173 IKAHPWFRGVAWDKLYEME----AAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRK 340 +KAHP+F + W+ L++ A+ P ++++ D + +D + + + S S Sbjct: 339 LKAHPFFESITWENLHQQTPPKLTAYLPAMSED-DEDCYGNYDNLLSQFGCMQVSSSSSS 397 Query: 341 AKLNSKDLS 367 L + D S Sbjct: 398 HSLCAVDAS 406
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G G ++IK HP+F + W+KLY E++ FKP V Sbjct: 282 LSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGR 341 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFV 373 DT +F + +P G PS A + SFV Sbjct: 342 PEDTFHFDP-EFTARTPTDSPGVPPSANAHHLFRGFSFV 379
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 5/102 (4%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LSPEA+ L+ L + +R+G G ++IK H +F + W+KLY E+ FKP Sbjct: 291 LSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR 350 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYT 382 DT F + +P G PS A + SFV T Sbjct: 351 PEDTFYFDP-EFTAKTPKDSPGIPPSANAHQLFRGFSFVAIT 391
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 41.2 bits (95), Expect = 0.002 Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 5/102 (4%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LSPEA+ L+ L + +R+G G ++IK H +F + W+KLY E+ FKP Sbjct: 291 LSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGR 350 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYT 382 DT F + +P G PS A + SFV T Sbjct: 351 PEDTFYFDP-EFTAKTPKDSPGIPPSANAHQLFRGFSFVAIT 391
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGS 325 G G IK H +FR + W+KL E++ +KP+ D+ DT NF K E P Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDK--EFTRQPVELT-- 641 Query: 326 GPSRKAKLNSKDLS-FVGYTYKN 391 P+ K + + D + F G++Y N Sbjct: 642 -PTDKLFIMNLDQNEFAGFSYTN 663
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGS 325 G G IK H +FR + W+KL E++ +KP+ D+ DT NF K E P Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDK--EFTRQPVELT-- 641 Query: 326 GPSRKAKLNSKDLS-FVGYTYKN 391 P+ K + + D + F G++Y N Sbjct: 642 -PTDKLFIMNLDQNEFAGFSYTN 663
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 40.8 bits (94), Expect = 0.003 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 8/99 (8%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQ--- 172 PPF +D I ++V +P LS EA L LL + R+G G D+ Sbjct: 545 PPFDGEDEDELFTAITE--HNVSYPKS--LSKEAVSLCKALLIKNPSKRLGCTGDDESAS 600 Query: 173 --IKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNF 277 IK HP+FR + W K+ +++ FKP++ + T+NF Sbjct: 601 RDIKEHPFFRRIDWFKIETRQIQPPFKPKLKTDRSTENF 639
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 40.8 bits (94), Expect = 0.003 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGA-----GAD 169 PPF +D+ I+H + V +P LS EA ++ + H+ G G D Sbjct: 605 PPFEADNEDDLFESILH--DDVLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGED 660 Query: 170 QIKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 IK HP+F+ + W L + M+ FKP++ + D NF Sbjct: 661 AIKQHPFFKEIDWVLLEQKKMKPPFKPRIKTKRDVNNF 698
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGAGADQIKAHPWFRGVAWDKLY--EMEAAFKPQVNDEL 262 LS EA+ L+ L + +R+G G ++IK H +F + WDKLY E++ FKP Sbjct: 296 LSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPD 355 Query: 263 DT 268 DT Sbjct: 356 DT 357
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 40.8 bits (94), Expect = 0.003 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 4/131 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD--QIK 178 PPFYS D I+H ++ P ++ A DL+ LL + G+ AD +IK Sbjct: 292 PPFYSQDVSQMYENILH--QPLQIPGGRTVA--ACDLLQSLLHKDQRQRLGSKADFLEIK 347 Query: 179 AHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLN 352 H +F + WD LY + F P V D ++F + + G P A + Sbjct: 348 NHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDP-EFTQEAVSKSIGCTPDTVASSS 406 Query: 353 SKDLSFVGYTY 385 +F+G++Y Sbjct: 407 GASSAFLGFSY 417
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 3/83 (3%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGS 325 G G IK H +FR + W+KL E++ +KP+ D+ DT NF K E P Sbjct: 586 GPEGERDIKDHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDK--EFTRQPVELT-- 641 Query: 326 GPSRKAKLNSKDLS-FVGYTYKN 391 P+ K + + D + F G++Y N Sbjct: 642 -PTDKLFIMNLDQNEFAGFSYTN 663
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/67 (35%), Positives = 38/67 (56%), Gaps = 3/67 (4%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDEL 262 L EA+DL+ +L + + R+G G I+ HP FR + W++L E++ F+P+V Sbjct: 602 LEREAKDLLVKLFVREPEKRLGVRG--DIRQHPLFREINWEELERKEIDPPFRPKVKSPY 659 Query: 263 DTQNFMK 283 D NF K Sbjct: 660 DCSNFDK 666
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 40.0 bits (92), Expect = 0.005 Identities = 32/92 (34%), Positives = 46/92 (50%), Gaps = 4/92 (4%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDH--RIGGAGADQIK 178 PPFY KI+ ++V FP +SP AR LI LL D + R+G G +I Sbjct: 202 PPFYDSSADAIYHKILE--SNVVFPH--YVSPVARCLITGLL-DKNRATRLGTKGICEIM 256 Query: 179 AHPWFRGVAWDKL--YEMEAAFKPQVNDELDT 268 HP+F+G+ W ++ +E F P N L + Sbjct: 257 GHPFFKGIDWHEVESRRIEPPFIPNPNTVLSS 288
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 39.3 bits (90), Expect = 0.008 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGA-----GAD 169 PPF +D+ I+H + V +P LS EA ++ + H+ G G D Sbjct: 604 PPFEADNEDDLFESILH--DDVLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGED 659 Query: 170 QIKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 IK HP+F+ + W L + ++ FKP++ + D NF Sbjct: 660 AIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNF 697
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 39.3 bits (90), Expect = 0.008 Identities = 35/106 (33%), Positives = 49/106 (46%), Gaps = 5/106 (4%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAG---ADQIK 178 PF DD IV+ + V++P LS EA ++ RLL R GAG A+ +K Sbjct: 720 PFPGDDEEEVFDSIVN--DEVRYP--RFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVK 775 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPP 310 HP+FR W L + ++ F P + D NF DE + P Sbjct: 776 KHPFFRLTDWSALLDKKVKPPFVPTIRGREDVSNF--DDEFTSEAP 819
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 39.3 bits (90), Expect = 0.008 Identities = 35/106 (33%), Positives = 49/106 (46%), Gaps = 5/106 (4%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAG---ADQIK 178 PF DD IV+ + V++P LS EA ++ RLL R GAG A+ +K Sbjct: 855 PFPGDDEEEVFDSIVN--DEVRYP--RFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVK 910 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPP 310 HP+FR W L + ++ F P + D NF DE + P Sbjct: 911 KHPFFRLTDWSALMDKKVKPPFVPTIRGREDVSNF--DDEFTSEAP 954
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 39.3 bits (90), Expect = 0.008 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGA-----GAD 169 PPF +D+ I+H + V +P LS EA ++ + H+ G G D Sbjct: 605 PPFEADNEDDLFESILH--DDVLYP--VWLSKEAVSILKAFMTKNPHKRLGCVAAQNGED 660 Query: 170 QIKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 IK HP+F+ + W L + ++ FKP++ + D NF Sbjct: 661 AIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNF 698
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 39.3 bits (90), Expect = 0.008 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGA-----GAD 169 PPF +D+ I+H + V +P LS EA ++ + H+ G G D Sbjct: 605 PPFEADNEDDLFESILH--DDVLYP--VWLSKEAVSILKAFMTKNPHKRLGCVASQNGED 660 Query: 170 QIKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 IK HP+F+ + W L + ++ FKP++ + D NF Sbjct: 661 AIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNF 698
>KPC1_NEUCR (P87253) Protein kinase C-like (EC 2.7.11.13)| Length = 1142 Score = 38.9 bits (89), Expect = 0.011 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 4/50 (8%) Frame = +2 Query: 140 DHRIGGAGAD--QIKAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 D R+G D +I + P+FR + WD +Y ++ F PQ+ DT NF Sbjct: 1057 DQRLGSGPTDAQEIMSQPFFRNINWDDIYHKRVQPPFLPQIKSATDTSNF 1106
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 38.9 bits (89), Expect = 0.011 Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 10/83 (12%) Frame = +2 Query: 89 RLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLYE--MEAAFKPQ-- 247 R SP+AR L +LLC D R+G G A ++K HP F+ + + +L +E FKP Sbjct: 411 RFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQ 470 Query: 248 ---VNDELDTQNFMKFDEMDNSP 307 D LD + F ++ P Sbjct: 471 AIYCKDVLDIEQFSTVKGVELEP 493
>KPC1_TRIRE (Q99014) Protein kinase C-like (EC 2.7.11.13)| Length = 1139 Score = 38.5 bits (88), Expect = 0.014 Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 4/50 (8%) Frame = +2 Query: 140 DHRIGGAGAD--QIKAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 D R+G D ++ + P+FR + WD +Y ++ F PQ+ DT NF Sbjct: 1054 DQRLGSGPTDAQEVMSQPFFRNINWDDIYHKRVQPPFLPQIKSATDTSNF 1103
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 38.5 bits (88), Expect = 0.014 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 5/99 (5%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G G ++IK HP+F + W+ LY E++ FKP V Sbjct: 282 LSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGR 341 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFV 373 DT +F + +P G PS A + SFV Sbjct: 342 PEDTFHFDP-EFTARTPTDSPGVPPSANAHHLFRGFSFV 379
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 38.5 bits (88), Expect = 0.014 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSR-LSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PF+ DD I V P R ++ E++D++ +L D D R+G G I+ Sbjct: 545 PFHGDDEDELFESI-----RVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTG--NIRI 597 Query: 182 HPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 HP+F+ + W L + +E FKP+V D NF Sbjct: 598 HPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNF 631
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 38.5 bits (88), Expect = 0.014 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSR-LSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PF+ DD I V P R ++ E++D++ +LL D R+G G IK Sbjct: 545 PFHGDDEDELFESI-----RVDTPHYPRWITKESKDILEKLLERDTTKRLGVTG--NIKI 597 Query: 182 HPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF 277 HP+F+ + W L + +E FKP+V D NF Sbjct: 598 HPFFKTINWTLLEKRAVEPPFKPKVKSPGDYSNF 631
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 38.5 bits (88), Expect = 0.014 Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 3/55 (5%) Frame = +2 Query: 65 HVKFPDDSRLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLY 220 +V+ PD SPE R L+ LL DV R+G G GA ++K H +F+G+ W +Y Sbjct: 410 NVQLPD--AFSPELRSLLEGLLQRDVSQRLGCYGGGARELKEHIFFKGIDWQYVY 462
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 38.5 bits (88), Expect = 0.014 Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 3/55 (5%) Frame = +2 Query: 65 HVKFPDDSRLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLY 220 +V+ PD SPE + L+ LL DV R+G G G+ ++K H +F+GV W +Y Sbjct: 410 NVELPDT--FSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVY 462
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 38.5 bits (88), Expect = 0.014 Identities = 36/123 (29%), Positives = 60/123 (48%), Gaps = 5/123 (4%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIK 178 PF DD IV+ + V++P LS EA ++ RLL + + R+G + A+ +K Sbjct: 856 PFPGDDEEEVFDSIVN--DEVRYP--RFLSTEAISIMRRLLRRNPERRLGASEKDAEDVK 911 Query: 179 AHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLN 352 HP+FR + W L + ++ F P + D NF DE + P P R+ ++ Sbjct: 912 KHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNF--DDEFTSEAPILT---PPREPRIL 966 Query: 353 SKD 361 S++ Sbjct: 967 SEE 969
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 38.5 bits (88), Expect = 0.014 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 5/99 (5%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G GA++IK H ++ + W+KLY E++ FKP V Sbjct: 285 LSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQ 344 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFV 373 DT F + +P G PS A + SFV Sbjct: 345 PDDTFYF-DTEFTSRTPKDSPGIPPSAGAHQLFRGFSFV 382
>G11A_ORYSA (P47997) Protein kinase G11A (EC 2.7.11.1)| Length = 589 Score = 38.5 bits (88), Expect = 0.014 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 2/103 (1%) Frame = +2 Query: 68 VKFPDDSRLSPEARDLICRLLC-DVDHRIG-GAGADQIKAHPWFRGVAWDKLYEMEAAFK 241 ++FP+ +S ARDLI LL + R+G GA +IK HP+F GV W + A Sbjct: 490 LRFPEYPVVSFSARDLIRGLLVKEPQQRLGCKRGATEIKQHPFFEGVNWALI---RCASP 546 Query: 242 PQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSF 370 P+V ++ + K + S PA S ++K+ + + F Sbjct: 547 PEVPRPVEIERPPK-QPVSTSEPAAAPSDAAQKSSDSYLEFDF 588
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 38.1 bits (87), Expect = 0.019 Identities = 42/138 (30%), Positives = 61/138 (44%), Gaps = 5/138 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ V +P LS EA + L + G+G D I Sbjct: 538 PPFDGEDEEELFQAIME--QTVTYPKS--LSREAVAICKGFLTKHPAKRLGSGPDGEPTI 593 Query: 176 KAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AH +FR + WD+L +E A F+P+ +NF KF + PA + P R Sbjct: 594 RAHGFFRWIDWDRLERLEIAPPFRPRPCGR-SGENFDKF--FTRAAPAL--TPPDRLVLA 648 Query: 350 NSKDLSFVGYTYKNFDAV 403 + F G+TY N D V Sbjct: 649 SIDQAEFQGFTYVNPDFV 666
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 37.7 bits (86), Expect = 0.024 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 5/99 (5%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G GA++IK H ++ + W+KLY E++ FKP V Sbjct: 274 LSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAVAQ 333 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFV 373 DT F + +P G PS A + SFV Sbjct: 334 PDDTFYF-DTEFTSRTPRDSPGIPPSAGAHQLFRGFSFV 371
>KPK7_ARATH (Q05999) Putative serine/threonine-protein kinase PK7 (EC 2.7.11.1)| Length = 578 Score = 37.7 bits (86), Expect = 0.024 Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 2/69 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIG-GAGADQIKA 181 PF D T +V ++FP+ +S ARDLI LL + HR+ GA +IK Sbjct: 455 PFRGGDNRATLFNVVG--QPLRFPEHPNVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQ 512 Query: 182 HPWFRGVAW 208 HP+F+ V W Sbjct: 513 HPFFQSVNW 521
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 37.7 bits (86), Expect = 0.024 Identities = 45/151 (29%), Positives = 66/151 (43%), Gaps = 5/151 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ V +P LS EA + L + G+G D I Sbjct: 553 PPFDGEDEEELFQAIME--QTVTYPKS--LSREAVAICKGFLTKHPGKRLGSGPDGEPTI 608 Query: 176 KAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AH +FR + W++L +E A F+P+ +NF KF + PA + P R Sbjct: 609 RAHGFFRWIDWERLERLEIAPPFRPRPCGR-SGENFDKF--FTRAAPA--VTPPDRLVLA 663 Query: 350 NSKDLSFVGYTYKNFDAVKGLKHADMQRSSS 442 + F G+TY N D V H D + SS Sbjct: 664 SIDQADFQGFTYVNPDFV----HPDARSPSS 690
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 37.7 bits (86), Expect = 0.024 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 5/99 (5%) Frame = +2 Query: 92 LSPEARDLICRLLC-DVDHRIGGA--GADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 LS EA+ L+ L + +R+G GA++IK H ++ + W+KLY E++ FKP V Sbjct: 285 LSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAVAQ 344 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFV 373 DT F + +P G PS A + SFV Sbjct: 345 PDDTFYF-DTEFTSRTPRDSPGIPPSAGAHQLFRGFSFV 382
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 37.4 bits (85), Expect = 0.032 Identities = 38/106 (35%), Positives = 49/106 (46%), Gaps = 6/106 (5%) Frame = +2 Query: 92 LSPEARDLICRLL-CDVDHRIGG--AGADQIKAHPWFRGVAWDKLY--EMEAAFKPQVND 256 +S EA ++ LL D RIG + A I H +FR + W L ++E FKPQV Sbjct: 537 ISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKH 596 Query: 257 ELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKD-LSFVGYTYKN 391 LDTQ F + + R P K L S D F G+TY N Sbjct: 597 PLDTQYFDRVFTRE-----RVRLTPIDKEILASMDQKQFHGFTYTN 637
>KPC1_COCHE (O42632) Protein kinase C-like (EC 2.7.11.13)| Length = 1174 Score = 37.4 bits (85), Expect = 0.032 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 2/44 (4%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 G A +I +H +FR + WD +Y ++ F PQ+ DT NF Sbjct: 1095 GPTDAQEIMSHAFFRNINWDDIYHKRVQPPFIPQITSPTDTSNF 1138
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 37.4 bits (85), Expect = 0.032 Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 3/55 (5%) Frame = +2 Query: 65 HVKFPDDSRLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLY 220 +V+ PD SPE + L+ LL DV R+G G A ++K H +FRG+ W +Y Sbjct: 410 NVELPDV--FSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVY 462
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 37.0 bits (84), Expect = 0.041 Identities = 21/49 (42%), Positives = 30/49 (61%), Gaps = 2/49 (4%) Frame = +2 Query: 68 VKFPDDSRLSPEARDLICRLLC-DVDHRIG-GAGADQIKAHPWFRGVAW 208 ++FP+ +S ARDLI LL + HR+ GA +IK HP+F+ V W Sbjct: 522 LRFPESPTVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQHPFFQNVNW 570
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 37.0 bits (84), Expect = 0.041 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 3/54 (5%) Frame = +2 Query: 68 VKFPDDSRLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLY 220 ++ P++ LS + RDL+ LL DV R+G G G ++K HP+F+ V W +Y Sbjct: 412 IELPNEG-LSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVY 464
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 37.0 bits (84), Expect = 0.041 Identities = 44/151 (29%), Positives = 66/151 (43%), Gaps = 5/151 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ V +P LS EA + L + G+G D I Sbjct: 553 PPFDGEDEEELFQAIME--QTVTYPKS--LSREAVAICKGFLTKHPGKRLGSGPDGEPTI 608 Query: 176 KAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AH +FR + W++L +E A F+P+ +NF KF + PA + P R Sbjct: 609 RAHGFFRWIDWERLERLEIAPPFRPRPCGR-SGENFDKF--FTRAAPAL--TPPDRLVLA 663 Query: 350 NSKDLSFVGYTYKNFDAVKGLKHADMQRSSS 442 + F G+TY N D V H D + +S Sbjct: 664 SIDQADFQGFTYVNPDFV----HPDARSPTS 690
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 37.0 bits (84), Expect = 0.041 Identities = 44/151 (29%), Positives = 66/151 (43%), Gaps = 5/151 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ V +P LS EA + L + G+G D I Sbjct: 553 PPFDGEDEEELFQAIME--QTVTYPKS--LSREAVAICKGFLTKHPGKRLGSGPDGEPTI 608 Query: 176 KAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AH +FR + W++L +E A F+P+ +NF KF + PA + P R Sbjct: 609 RAHGFFRWIDWERLERLEIAPPFRPRPCGR-SGENFDKF--FTRAAPAL--TPPDRLVLA 663 Query: 350 NSKDLSFVGYTYKNFDAVKGLKHADMQRSSS 442 + F G+TY N D V H D + +S Sbjct: 664 SIDQADFQGFTYVNPDFV----HPDARSPTS 690
>PKN1_MOUSE (P70268) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) Length = 946 Score = 37.0 bits (84), Expect = 0.041 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIK 178 PF DD IV+ + V++P LS EA ++ RLL + + R+G A+ +K Sbjct: 818 PFPGDDEEEVFDSIVN--DEVRYP--RFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVK 873 Query: 179 AHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 P+FR + WD L + F P ++ D NF Sbjct: 874 KQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNF 908
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 36.6 bits (83), Expect = 0.054 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFP---DDSRLSPEARDLICRLLC-DVDHRIGG-AGADQ 172 PF + T I+H V FP D +S ++LI +LL D + R+G AGA Sbjct: 421 PFKGKNRNMTFSNILH--KDVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAAD 478 Query: 173 IKAHPWFRGVAWDKLYEMEAAFKPQV 250 +K HP+F+ V W L E P++ Sbjct: 479 VKLHPFFKNVQWALLRHTEPPIIPKL 504
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 36.6 bits (83), Expect = 0.054 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Frame = +2 Query: 104 ARDLICRLL-CDVDHRIGGA--GADQIKAHPWFRGVAWDKLYEMEAA--FKPQVNDELDT 268 A+DL+ +LL D R+G GA + H WF + WD + M+ P + DT Sbjct: 251 AKDLVKKLLQVDRTQRLGNQKDGAADVMNHKWFTDIDWDDVQNMKLTPPIIPTLYSNGDT 310 Query: 269 QNFMKFDE 292 NF +DE Sbjct: 311 GNFDSYDE 318
>CDPK3_PLAF7 (Q9NJU9) Calcium-dependent protein kinase 3 (EC 2.7.11.1) (PfCDPK3)| Length = 562 Score = 36.6 bits (83), Expect = 0.054 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICR-LLCDVDHRIGGAGADQIK 178 YPPF+ + + + K + + +S EA+DLI R L D D RI + A Q Sbjct: 312 YPPFFGESDHEILSMVKKGKYQFKGKEWNNISEEAKDLIKRCLTMDADKRICASEALQ-- 369 Query: 179 AHPWFR 196 HPWF+ Sbjct: 370 -HPWFK 374
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 36.6 bits (83), Expect = 0.054 Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 7/136 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSR-LSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PF+ DD I V P R ++ E++D++ +L D R+G G I+ Sbjct: 545 PFHGDDEDELFESI-----RVDTPHYPRWITKESKDIMEKLFERDPAKRLGVTG--NIRL 597 Query: 182 HPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNS 355 HP+F+ + W+ L ++E FKP+V D NF E N P S + ++ Sbjct: 598 HPFFKTINWNLLEKRKVEPPFKPKVKSPSDYSNF--DPEFLNEKPQLSFSDKNLIDSMDQ 655 Query: 356 ---KDLSFVGYTYKNF 394 K SFV Y+ F Sbjct: 656 TAFKGFSFVNPKYEQF 671
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 36.6 bits (83), Expect = 0.054 Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 5/133 (3%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSR-LSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PF+ DD I V P R ++ E++D++ +L + R+G G IK Sbjct: 547 PFHGDDEDELFESI-----RVDTPHYPRWITKESKDILEKLFEREPTKRLGMTG--NIKI 599 Query: 182 HPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNS 355 HP+F+ + W L + +E F+P+V D N FD+ + AR S K ++S Sbjct: 600 HPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSN---FDQEFLNEKARLSY--SDKNLIDS 654 Query: 356 KDLS-FVGYTYKN 391 D S F G+++ N Sbjct: 655 MDQSAFAGFSFVN 667
>KPC1_ASPNG (Q00078) Protein kinase C-like (EC 2.7.11.13)| Length = 1096 Score = 36.6 bits (83), Expect = 0.054 Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 2/44 (4%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 G A ++ +H +FR + WD +Y + F PQ++ DT NF Sbjct: 1017 GPTDAQEVMSHAFFRNINWDDIYHKRVPPPFLPQISSPTDTSNF 1060
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 36.6 bits (83), Expect = 0.054 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEA--AFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPS 334 G IK+H +FR + WD L + +A F+PQ+ D+ N FD S P + P Sbjct: 508 GFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDN---FDTQFTSEPVQ--LTPD 562 Query: 335 RKAKLNSKDLS-FVGYTYKN 391 + + D S F G+ Y N Sbjct: 563 DEDAIKRIDQSEFEGFEYIN 582
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 36.2 bits (82), Expect = 0.070 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ ++V +P LS EA + L+ + G G + + Sbjct: 535 PPFDGEDEDELFQSIME--HNVSYPKS--LSKEAVSICKGLMTKQPAKRLGCGPEGERDV 590 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 + H +FR + W+KL E++ FKP+V + +NF KF P + P + Sbjct: 591 REHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKF--FTRGQPVL--TPPDQLVIA 645 Query: 350 NSKDLSFVGYTYKN 391 N F G++Y N Sbjct: 646 NIDQSDFEGFSYVN 659
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 36.2 bits (82), Expect = 0.070 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D I ++V +P LS EA L LL + G G + I Sbjct: 517 PPFDGEDEEELFTSITD--HNVSYP--KALSREAVSLCKGLLTKTPAKRLGCGPNGERDI 572 Query: 176 KAHPWFRGVAWDK--LYEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 K +FR + W++ L E++ +KP++ D NF + + + A + + + Sbjct: 573 KDRAFFRPIQWERIELREVQPPYKPRIKSRKDVSNF----DREFTSEAPNVTPTDKLFIM 628 Query: 350 NSKDLSFVGYTYKN 391 N F G++Y N Sbjct: 629 NLDQCEFSGFSYVN 642
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 35.8 bits (81), Expect = 0.092 Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 1/62 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIKAH 184 PF D +T RKI + V FP++ +S + +DLI R+L + + RI G IK H Sbjct: 352 PFIDDYILTLHRKIKN--EAVVFPEEPEVSEDLKDLILRMLDKNPETRI---GVSDIKLH 406 Query: 185 PW 190 PW Sbjct: 407 PW 408
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 35.8 bits (81), Expect = 0.092 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ ++V +P LS EA + L+ + G G + + Sbjct: 535 PPFDGEDEDELFQSIME--HNVSYPKS--LSKEAVSICKGLMTKHPAKRLGCGPEGERDV 590 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 + H +FR + W+KL E++ FKP+V + +NF KF P + P + Sbjct: 591 REHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKF--FTRGQPVL--TPPDQLVIA 645 Query: 350 NSKDLSFVGYTYKN 391 N F G++Y N Sbjct: 646 NIDQSDFEGFSYVN 659
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 35.8 bits (81), Expect = 0.092 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ ++V +P LS EA + L+ + G G + + Sbjct: 535 PPFDGEDEDELFQSIME--HNVSYPKS--LSKEAVSICKGLMTKHPAKRLGCGPEGERDV 590 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 + H +FR + W+KL E++ FKP+V + +NF KF P + P + Sbjct: 591 REHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKF--FTRGQPVL--TPPDQLVIA 645 Query: 350 NSKDLSFVGYTYKN 391 N F G++Y N Sbjct: 646 NIDQSDFEGFSYVN 659
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 35.8 bits (81), Expect = 0.092 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ ++V +P LS EA + L+ + G G + + Sbjct: 535 PPFDGEDEDELFQSIME--HNVSYPKS--LSKEAVSICKGLMTKHPGKRLGCGPEGERDV 590 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 + H +FR + W+KL E++ FKP+V + +NF KF P + P + Sbjct: 591 REHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKF--FTRGQPVL--TPPDQLVIA 645 Query: 350 NSKDLSFVGYTYKN 391 N F G++Y N Sbjct: 646 NIDQSDFEGFSYVN 659
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 35.8 bits (81), Expect = 0.092 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 10/83 (12%) Frame = +2 Query: 89 RLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLYE--MEAAFKPQ-- 247 R S +AR L +LL D R+G G GA ++K HP F+ + + +L +E FKP Sbjct: 411 RFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQ 470 Query: 248 ---VNDELDTQNFMKFDEMDNSP 307 D LD + F +D P Sbjct: 471 AIYCKDVLDIEQFSTVKGVDLEP 493
>PKN1_RAT (Q63433) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protease-activated kinase 1) (PAK-1) Length = 946 Score = 35.8 bits (81), Expect = 0.092 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIK 178 PF DD IV+ + V++P LS EA ++ RLL + + R+G A+ +K Sbjct: 818 PFPGDDEEEVFDSIVN--DEVRYP--RFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVK 873 Query: 179 AHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 P+FR + WD L + F P ++ D NF Sbjct: 874 KQPFFRTLDWDALLARRLPPPFVPTLSGRTDVSNF 908
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 35.4 bits (80), Expect = 0.12 Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ ++V +P LS EA + L+ + G G + + Sbjct: 535 PPFDGEDEDELFQSIME--HNVSYPKS--LSKEAVSICKGLMTKHPAKRLGCGPEGERDV 590 Query: 176 KAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 + H +FR + W+KL E++ FKP+V + +NF KF P + P + Sbjct: 591 REHAFFRRIDWEKLENREIQPPFKPKVCGK-GAENFDKF--FTRGQPV--VTPPDQLVIA 645 Query: 350 NSKDLSFVGYTYKN 391 N F G++Y N Sbjct: 646 NIDQSDFEGFSYVN 659
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 35.4 bits (80), Expect = 0.12 Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 2/79 (2%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPS 334 G I AHP+FR V WD + + + FKP ++ E NF + N P Sbjct: 504 GFADIMAHPFFRNVDWDLMEQKQVVPPFKPNISGEFGLDNFDA--QFTNEPIQLTPDDDD 561 Query: 335 RKAKLNSKDLSFVGYTYKN 391 K++ + F G+ Y N Sbjct: 562 AVKKIDQSE--FEGFEYIN 578
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 35.4 bits (80), Expect = 0.12 Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PPF D T R+I+ R +KFP +SP+ARDLI RLL + RI ++K+ Sbjct: 295 PPFEEDTKEMTYRRIL--RCDLKFP--LNVSPQARDLIVRLLQFEPSKRI---PLSEVKS 347 Query: 182 HPW 190 H W Sbjct: 348 HAW 350
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 35.4 bits (80), Expect = 0.12 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGA--GADQIK 178 PF DD IV+ + V++P LS EA ++ RLL + + R+G + A+ +K Sbjct: 814 PFPGDDEEEVFDSIVN--DEVRYP--RFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVK 869 Query: 179 AHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 P+FR + W+ L + F P ++ D NF Sbjct: 870 KQPFFRTLGWEALLARRLPPPFVPTLSGRTDVSNF 904
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 35.4 bits (80), Expect = 0.12 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 10/83 (12%) Frame = +2 Query: 89 RLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLYE--MEAAFKPQ-- 247 R SP+AR L +L D R+G G GA ++K HP F+ + + +L +E FKP Sbjct: 411 RFSPQARSLCSQLPNKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQ 470 Query: 248 ---VNDELDTQNFMKFDEMDNSP 307 D LD + F +D P Sbjct: 471 AIYCKDVLDIEQFSTVKGVDLEP 493
>CDPK3_PLAYO (Q7RAV5) Calcium-dependent protein kinase 3 (EC 2.7.11.1)| Length = 538 Score = 35.4 bits (80), Expect = 0.12 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 1/66 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICR-LLCDVDHRIGGAGADQIK 178 YPPFY + + + + K + + +S EA+DLI R L D RI A + Sbjct: 306 YPPFYGESDHEILSMVKKGKYNFKGKEWNNISDEAKDLIKRCLTIDSGKRI---NASEAL 362 Query: 179 AHPWFR 196 HPWF+ Sbjct: 363 KHPWFK 368
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 35.0 bits (79), Expect = 0.16 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 2/69 (2%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGG-AGADQIKA 181 PF + T I+H + FP +S R LI LL D R+G GA++IK Sbjct: 803 PFRGKNRQKTFANILH--KDLTFPSSIPVSLVGRQLINTLLNRDPSSRLGSKGGANEIKQ 860 Query: 182 HPWFRGVAW 208 H +FRG+ W Sbjct: 861 HAFFRGINW 869
>ATG1_SCHPO (Q9Y7T4) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 830 Score = 35.0 bits (79), Expect = 0.16 Identities = 14/42 (33%), Positives = 27/42 (64%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL 130 PPF + + + R+I ++ +KFP+++ + P+ + LIC LL Sbjct: 247 PPFKAPNHVELLRRIQKAKDVIKFPEEAFIHPDIKTLICALL 288
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 35.0 bits (79), Expect = 0.16 Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 5/151 (3%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGAD---QI 175 PPF +D + I+ V +P LS EA + L + G+G D I Sbjct: 553 PPFDGEDEEELFQAIME--QTVTYPKS--LSREAVAICKGFLTKHPGKRLGSGPDGEPTI 608 Query: 176 KAHPWFRGVAWDKLYEME--AAFKPQVNDELDTQNFMKFDEMDNSPPARRGSGPSRKAKL 349 +AH +FR + W++L +E F+P+ +NF KF + PA + P R Sbjct: 609 RAHGFFRWIDWERLERLEIPPPFRPRPCGR-SGENFDKF--FTRAAPAL--TPPDRLVLA 663 Query: 350 NSKDLSFVGYTYKNFDAVKGLKHADMQRSSS 442 + F G+TY N D V H D + +S Sbjct: 664 SIDQADFQGFTYVNPDFV----HPDARSPTS 690
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 35.0 bits (79), Expect = 0.16 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 2/79 (2%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPS 334 G I+ HP+FR V WD + + + FKP ++ E NF + N P Sbjct: 503 GFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNF--DSQFTNEPVQLTPDDDD 560 Query: 335 RKAKLNSKDLSFVGYTYKN 391 K++ + F G+ Y N Sbjct: 561 IVRKIDQSE--FEGFEYIN 577
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 35.0 bits (79), Expect = 0.16 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 2/79 (2%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPS 334 G I+ HP+FR V WD + + + FKP ++ E NF + N P Sbjct: 502 GFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNF--DSQFTNEPVQLTPDDDD 559 Query: 335 RKAKLNSKDLSFVGYTYKN 391 K++ + F G+ Y N Sbjct: 560 IVRKIDQSE--FEGFEYIN 576
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 35.0 bits (79), Expect = 0.16 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 2/79 (2%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEAA--FKPQVNDELDTQNFMKFDEMDNSPPARRGSGPS 334 G I+ HP+FR V WD + + + FKP ++ E NF + N P Sbjct: 503 GFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNF--DSQFTNEPVQLTPDDDD 560 Query: 335 RKAKLNSKDLSFVGYTYKN 391 K++ + F G+ Y N Sbjct: 561 IVRKIDQSE--FEGFEYIN 577
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 34.7 bits (78), Expect = 0.21 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 3/55 (5%) Frame = +2 Query: 65 HVKFPDDSRLSPEARDLICRLLC-DVDHRIG--GAGADQIKAHPWFRGVAWDKLY 220 +V+ P+ L E ++L+ LL DV R+G G GAD++K H +F G+ W ++Y Sbjct: 411 NVELPESFSL--ELKNLLEMLLQRDVSKRLGCMGNGADEVKMHNFFCGIDWHQVY 463
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 34.7 bits (78), Expect = 0.21 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEA--AFKPQVNDELDTQNF 277 G IK+H +FR + WD L + + F+PQ+ D+ NF Sbjct: 508 GFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNF 548
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 34.7 bits (78), Expect = 0.21 Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEA--AFKPQVNDELDTQNF 277 G IK+H +FR + WD L + + F+PQ+ D+ NF Sbjct: 508 GFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNF 548
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 34.3 bits (77), Expect = 0.27 Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGS 325 G G IK H +FR + W+KL E++ +KP+ + +NF +F PP + Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGR-NAENFDRF--FTRHPPVL--T 640 Query: 326 GPSRKAKLNSKDLSFVGYTYKNFDAVK 406 P ++ N F G+++ N + +K Sbjct: 641 PPDQEVIRNIDQSEFEGFSFVNSEFLK 667
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 34.3 bits (77), Expect = 0.27 Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMKFDEMDNSPPARRGS 325 G G IK H +FR + W+KL E++ +KP+ + +NF +F PP + Sbjct: 586 GPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGR-NAENFDRF--FTRHPPVL--T 640 Query: 326 GPSRKAKLNSKDLSFVGYTYKNFDAVK 406 P ++ N F G+++ N + +K Sbjct: 641 PPDQEVIRNIDQSEFEGFSFVNSEFLK 667
>CBK1_EMENI (P0C1B1) Serine/threonine-protein kinase cbk1 (EC 2.7.11.1)| Length = 884 Score = 34.3 bits (77), Expect = 0.27 Identities = 15/45 (33%), Positives = 24/45 (53%) Frame = +2 Query: 143 HRIGGAGADQIKAHPWFRGVAWDKLYEMEAAFKPQVNDELDTQNF 277 H + A IK+H +FRG+ W++++ F P V DT+ F Sbjct: 736 HYVYPDDATDIKSHRFFRGINWEQIHRTSPPFIPMVRGWEDTRYF 780
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 33.9 bits (76), Expect = 0.35 Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGG-AGADQI 175 Y PF T ++ + +KFP S + + LI RLL D R+G GA+++ Sbjct: 889 YTPFRGKTRQKTFTNVL--QKDLKFPASIPASLQVKQLIFRLLQRDPKKRLGCFEGANEV 946 Query: 176 KAHPWFRGVAW 208 K H +F+G+ W Sbjct: 947 KQHSFFKGINW 957
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 33.9 bits (76), Expect = 0.35 Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKLYEMEA--AFKPQVNDELDTQN 274 G IK+H +FR + WD L + +A F+PQ+ D+ N Sbjct: 507 GFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDN 546
>KKCC1_HUMAN (Q8N5S9) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 33.9 bits (76), Expect = 0.35 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIKAH 184 PF D + RKI + V FP++ +S E +DLI ++L + + RI G IK H Sbjct: 352 PFIDDFILALHRKIKN--EPVVFPEEPEISEELKDLILKMLDKNPETRI---GVPDIKLH 406 Query: 185 PW 190 PW Sbjct: 407 PW 408
>ATG1_YEAST (P53104) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Autophagy protein 3) (Cytoplasm to vacuole targeting protein 10) Length = 897 Score = 33.9 bits (76), Expect = 0.35 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIG 154 PPF + + + +KI + + FP + PE ++LIC LL D RIG Sbjct: 265 PPFRASNHLELFKKIKRANDVITFPSYCNIEPELKELICSLLTFDPAQRIG 315
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 33.5 bits (75), Expect = 0.46 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKF--PDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 PF D RK + V++ PD +SPE RDLI R+ V + +I+ Sbjct: 218 PFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPECRDLIARIF--VANPATRISIPEIRN 275 Query: 182 HPWF 193 HPWF Sbjct: 276 HPWF 279
>LEU2_THEFY (Q47SA3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 33.5 bits (75), Expect = 0.46 Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 8/135 (5%) Frame = +2 Query: 92 LSPEARDLICRLLCDVDHRIGGAGADQ-----IKAHPWF-RGVAWDKLYEMEAAFKPQVN 253 LS EAR IC + + R G DQ +K P +G WD+ E Sbjct: 211 LSMEARMTICNMSIEAGARAGMIAPDQTTFDYLKGRPHAPKGELWDQAVEYWKTLPTDEG 270 Query: 254 DELDTQNFMKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYT--YKNFDAVKGLKHADM 427 D + F+ DE+ SP G+ P + L+S +T + A K L + D+ Sbjct: 271 AVFDKEVFLNADEL--SPFVTWGTNPGQGVPLDSVVPDPESFTDPVERAAAEKALAYMDL 328 Query: 428 QRSSSLTRPSIGAIF 472 + + + I +F Sbjct: 329 KPGTRMRDIKIDTVF 343
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 33.5 bits (75), Expect = 0.46 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF++D K++ R K R+S A+DLI ++LC A ++ H Sbjct: 271 PPFWADTQSGIYEKVLDGRIDFKSNRWPRISDSAKDLIKKMLCPYPSE--RLKAHEVLKH 328 Query: 185 PWF--RGVAWDK 214 PW GVA ++ Sbjct: 329 PWICDNGVATNR 340
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 33.1 bits (74), Expect = 0.60 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKF--PDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 PF + RK + V++ PD +SPE RDLI R+ V + +IK Sbjct: 217 PFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECRDLITRIF--VGNPASRITMPEIKN 274 Query: 182 HPWF 193 HPWF Sbjct: 275 HPWF 278
>KAPL_APLCA (P21901) Spermatozoon-associated protein kinase (EC 2.7.11.1) (SAK)| (C-APL-B) Length = 351 Score = 33.1 bits (74), Expect = 0.60 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 5/102 (4%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGA--GADQ 172 + PF P+ IV R + FP S P RDL+ ++ DV R G GA Sbjct: 236 FVPFDHKVPLKLYELIVECR--LTFP--SFFKPTLRDLLTNIIQVDVTRRFGNLRNGALD 291 Query: 173 IKAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNFMKFDE 292 I HPWF+ + K+ +A + P + + Q F K+ E Sbjct: 292 IINHPWFKDTDFRKILMKAEKAPWVPNLKGQWIHQTFDKWTE 333
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 32.7 bits (73), Expect = 0.78 Identities = 22/66 (33%), Positives = 32/66 (48%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + T I+ K+ S +S E +DLI R+L R A ++I+ H Sbjct: 213 PPFQEANDSETLTMIMD----CKYTVPSHVSKECKDLITRMLQRDPKR--RASLEEIENH 266 Query: 185 PWFRGV 202 PW +GV Sbjct: 267 PWLQGV 272
>ATG1_PICAN (Q8TFN2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Peroxisome degradation deficient protein 7) Length = 804 Score = 32.7 bits (73), Expect = 0.78 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 8/112 (7%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + + + RKI ++ + FP +S E D + RL+C + +KA+ Sbjct: 248 PPFRASNHVELLRKIEKSKDEITFP----VSAEVPDDLVRLICGL-----------LKAN 292 Query: 185 P----WFRGVAWDKL--YEMEAAFKPQVNDELDTQNFMK--FDEMDNSPPAR 316 P F+ D L Y+++ A +P +D Q F+ + SPPA+ Sbjct: 293 PTERMGFQEFFNDPLIVYDVQCADEPLECSNVDEQLFISEYLPNLKTSPPAK 344
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 32.7 bits (73), Expect = 0.78 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHV--KFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKA 181 PF D RK + V K PD +S E + LI R+ V++ + +IK+ Sbjct: 199 PFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAECKQLIARIF--VNNPLRRITMKEIKS 256 Query: 182 HPWF 193 HPWF Sbjct: 257 HPWF 260
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 32.7 bits (73), Expect = 0.78 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQIKA 181 PPF S T R+IV + +KFP L A+DLI +LL + R+ +Q+ A Sbjct: 274 PPFESPSHSETYRRIV--KVDLKFPSSMPLG--AKDLISKLLKHNPSQRLP---LEQVSA 326 Query: 182 HPWFR 196 HPW R Sbjct: 327 HPWVR 331
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 32.7 bits (73), Expect = 0.78 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQIKA 181 PPF + + T + I+H + PD +S A DLI +LL D R+ D+I Sbjct: 310 PPFVAGNEYLTFQSILHLSYEIP-PD---ISDVASDLIKKLLVLDPKDRLT---VDEIHQ 362 Query: 182 HPWFRGVAWDK-LYEM 226 HP+F G+ +D L+E+ Sbjct: 363 HPFFNGIKFDNTLWEL 378
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 32.3 bits (72), Expect = 1.0 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Frame = +2 Query: 8 PFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIKAH 184 PF + + RKI + V FP++ +S E +DLI ++L + + RI G IK H Sbjct: 352 PFIDEYILALHRKIKN--EAVVFPEEPEVSEELKDLILKMLDKNPETRI---GVSDIKLH 406 Query: 185 PW 190 PW Sbjct: 407 PW 408
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 32.3 bits (72), Expect = 1.0 Identities = 22/66 (33%), Positives = 32/66 (48%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + T I+ K+ R+S RDLI R+L R A ++I++H Sbjct: 213 PPFQEANDSETLTMIMD----CKYTVPPRVSAGCRDLITRMLQRDPKR--RASLEEIESH 266 Query: 185 PWFRGV 202 PW +GV Sbjct: 267 PWLQGV 272
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 32.3 bits (72), Expect = 1.0 Identities = 22/66 (33%), Positives = 32/66 (48%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLCDVDHRIGGAGADQIKAH 184 PPF + T I+ K+ R+S RDLI R+L R A ++I++H Sbjct: 213 PPFQEANDSETLTMIMD----CKYTVPPRVSAGCRDLITRMLQRDPKR--RASLEEIESH 266 Query: 185 PWFRGV 202 PW +GV Sbjct: 267 PWLQGV 272
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 32.3 bits (72), Expect = 1.0 Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIK 178 YPPFY + KI + P +S A+D IC LL D + R ++ Sbjct: 216 YPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERY---TCEKAL 272 Query: 179 AHPWFRG 199 +HPW G Sbjct: 273 SHPWIDG 279
>YGM4_YEAST (P53129) Hypothetical 73.5 kDa protein in MET13-RPS2 intergenic| region Length = 644 Score = 32.0 bits (71), Expect = 1.3 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Frame = -1 Query: 576 RTTPGYGLIGSPEERVCMCVSFPFG----SLDDSMPFDPNIAPIEGLVNDELLCISACFN 409 R T YGLI +P+ ++C CV P G + D + F + L + L + CF Sbjct: 354 RGTLLYGLIIAPQNKLC-CVLRPRGHTLHTTDLHLLFCLISHQFQNLDETQELWVPICFP 412 Query: 408 PFTASKFLYVY 376 F +S FLY Y Sbjct: 413 KFNSSGFLYCY 423
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 32.0 bits (71), Expect = 1.3 Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIKA 181 PPF +D T R+I + V+F +S EARDL+ +LL + +HR+ G + Sbjct: 334 PPFETDTHQETYRRI----SKVEFQYPPYVSEEARDLVSKLLKHNPNHRLPLKG---VLE 386 Query: 182 HPW 190 HPW Sbjct: 387 HPW 389
>PKD1_DICDI (P34100) Developmentally-regulated protein kinase 1 (EC 2.7.11.1)| (Fragment) Length = 416 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Frame = +2 Query: 83 DSRLSPEARDLICRLLC-DVDHRIGGAGADQIKAHPWFRGVAWDKLYEMEAAFKPQVNDE 259 +S LS E +D I +LL D R+G + I+ H WF + W + K Q++ Sbjct: 254 NSYLSDEIKDFIFQLLSVDPSKRLGTFDSCSIRNHKWFSDINW-----LHLESKYQIDGP 308 Query: 260 LDTQN 274 L T N Sbjct: 309 LSTLN 313
>KS6C1_MOUSE (Q8BLK9) Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa| ribosomal protein S6 kinase) Length = 1056 Score = 32.0 bits (71), Expect = 1.3 Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 3/45 (6%) Frame = +2 Query: 92 LSPEARDLICRLL-CDVDHRIGG--AGADQIKAHPWFRGVAWDKL 217 +S EAR LI +LL + R+G AG + IK+HP+F V W +L Sbjct: 1010 VSEEARSLIQQLLQFNPMERLGAGVAGVEDIKSHPFFTPVDWAEL 1054
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIK 178 YPPF+ +D ++I P+ ++PEA+DLI ++L + RI A A Sbjct: 210 YPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEA---L 266 Query: 179 AHPW 190 HPW Sbjct: 267 KHPW 270
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIK 178 YPPF+ +D ++I P+ ++PEA+DLI ++L + RI A A Sbjct: 210 YPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEA---L 266 Query: 179 AHPW 190 HPW Sbjct: 267 KHPW 270
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIK 178 YPPF+ +D ++I P+ ++PEA+DLI ++L + RI A A Sbjct: 210 YPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEA---L 266 Query: 179 AHPW 190 HPW Sbjct: 267 KHPW 270
>KS6C1_HUMAN (Q96S38) Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa| ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) Length = 1066 Score = 31.6 bits (70), Expect = 1.7 Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 3/45 (6%) Frame = +2 Query: 92 LSPEARDLICRLL-CDVDHRIGG--AGADQIKAHPWFRGVAWDKL 217 +S EAR LI +LL + R+G AG + IK+HP+F V W +L Sbjct: 1020 VSEEARSLIQQLLQFNPLERLGAGVAGVEDIKSHPFFTPVDWAEL 1064
>PKH3_YEAST (Q03306) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| (Pkb-activating kinase homolog 3) Length = 898 Score = 31.6 bits (70), Expect = 1.7 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 6/75 (8%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVH----WRNHVKFPDD-SRLSPEARDLICRLLC-DVDHRIGGAGA 166 PPF ++ + T KIV W + + + S ++P +L+ ++L +V+ RI Sbjct: 228 PPFRGENELKTFEKIVALDYPWGPNNRINNSTSPINPLVINLVQKILVIEVNERIS---L 284 Query: 167 DQIKAHPWFRGVAWD 211 +QIK HP+F V W+ Sbjct: 285 EQIKRHPYFSKVDWN 299
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 31.6 bits (70), Expect = 1.7 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNF 277 G +I HP+F+ + W +L ++E F+P++ D NF Sbjct: 604 GEHEILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNF 644
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 31.6 bits (70), Expect = 1.7 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 2/44 (4%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNF 277 G G I+ H +FR + W+KL E++ F P V + +NF Sbjct: 570 GPTGEQDIREHQFFRRIDWEKLANREIQPPFVPSVRNPRAAENF 613
>MYB_MOUSE (P06876) Myb proto-oncogene protein (C-myb)| Length = 636 Score = 31.6 bits (70), Expect = 1.7 Identities = 16/34 (47%), Positives = 21/34 (61%) Frame = -2 Query: 296 PSHQTS*NSVYPIHHLLEA*MLLPFHKVYPMQLH 195 PS Q+S NS YP +H+ EA + H YP+ LH Sbjct: 234 PSGQSSVNSEYPYYHIAEA-QNISSHVPYPVALH 266
>PKH3_ASHGO (Q753D9) Serine/threonine-protein kinase PKH3 (EC 2.7.11.1)| Length = 726 Score = 31.6 bits (70), Expect = 1.7 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGADQIKA 181 PPF + + T +IV+ + P +P A L+ ++L D R +QIK Sbjct: 215 PPFRGQNEMETFEQIVNLDYTWRIP----ANPLAAGLVSKILVLDPSQRYT---LEQIKK 267 Query: 182 HPWFRGVAWD 211 H WF GV W+ Sbjct: 268 HKWFSGVDWN 277
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 31.6 bits (70), Expect = 1.7 Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIK 178 YPPF+ +D ++I P+ ++PEA+DLI ++L + RI A A Sbjct: 210 YPPFWDEDQHRLYQQIKARAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEA---L 266 Query: 179 AHPW 190 HPW Sbjct: 267 KHPW 270
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 31.6 bits (70), Expect = 1.7 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIK 178 YPPFY + KI + P +S A+D IC LL D + R ++ Sbjct: 216 YPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERY---TCEKAL 272 Query: 179 AHPWFRG 199 HPW G Sbjct: 273 RHPWIDG 279
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 31.6 bits (70), Expect = 1.7 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Frame = +2 Query: 2 YPPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIK 178 YPPFY + KI + P +S A+D IC LL D + R ++ Sbjct: 216 YPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERY---TCEKAL 272 Query: 179 AHPWFRG 199 HPW G Sbjct: 273 RHPWIDG 279
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 31.6 bits (70), Expect = 1.7 Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Frame = +2 Query: 152 GGAGADQIKAHPWFRGVAWDKLY--EMEAAFKPQVNDELDTQNF 277 G A+ + HP+F + WD +Y + + P +N DT+ F Sbjct: 929 GPNDAEDVMTHPFFSNINWDDIYHKRTQPPYIPSLNSPTDTKYF 972
>PDPK1_DROME (Q9W0V1) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (dPDK-1) (Serine/threonine-protein kinase 61C) (dSTPK61) Length = 836 Score = 31.2 bits (69), Expect = 2.3 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGA----D 169 PPF + ++I+ V FP +A DL+ +LL D R+G + Sbjct: 508 PPFRGSNDYVIFKEILDCA--VDFPQG--FDKDAEDLVRKLLRVDPRDRLGAQDEFGYYE 563 Query: 170 QIKAHPWFRGVAWDKL 217 I+AHP+F G+ W L Sbjct: 564 SIRAHPFFAGIDWQTL 579
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 31.2 bits (69), Expect = 2.3 Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Frame = +2 Query: 161 GADQIKAHPWFRGVAWDKL--YEMEAAFKPQVNDELDTQNF 277 G +I HP+F+ + W +L ++E F+P++ D NF Sbjct: 604 GEHEILRHPFFKEIDWVQLNHRQLEPPFRPRIKSREDVSNF 644
>ATG1_ASPFU (Q4WPF2) Serine/threonine-protein kinase atg1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 973 Score = 31.2 bits (69), Expect = 2.3 Identities = 15/42 (35%), Positives = 24/42 (57%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL 130 PPF + + + RKI + +KFP+++ S E + LI LL Sbjct: 268 PPFRATNHVELLRKIEKGEDRIKFPEENPASDEIKALIRALL 309
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 31.2 bits (69), Expect = 2.3 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Frame = +2 Query: 14 YSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLL-CDVDHRIGGAGADQIKAHPW 190 Y D I R + + V FP L+ E +DLI R+L DV+ R+ D+I +H W Sbjct: 216 YDDSDIKKLR--IQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRL---HIDEILSHSW 270 Query: 191 FR 196 + Sbjct: 271 LQ 272
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 31.2 bits (69), Expect = 2.3 Identities = 42/171 (24%), Positives = 71/171 (41%), Gaps = 20/171 (11%) Frame = +2 Query: 89 RLSPEARDLICRLLC--DVDHRIG--GAGADQIKAHPWFRGVAWDKLYE--MEAAFKPQ- 247 + S EA+ IC++L D R+G GA ++K HP+FR + + +L ++ F P Sbjct: 411 KFSEEAKS-ICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDP 469 Query: 248 ----VNDELDTQNF-----MKFDEMDNSPPARRGSGPSRKAKLNSKDLSFVGYTYKNFDA 400 D LD + F + D D+ ++ +G S S+ + + N Sbjct: 470 RAVYCKDVLDIEQFSTVKGVNLDHTDDDFYSKFSTG-SVPIPWQSEMIETECFKELNVFG 528 Query: 401 VKGLKHADMQRSSSLTRPSIG---AIFGSNGMESSR-EPNGKDTHMHTLSS 541 G D+ RS P G +F +S+ PN K + H ++S Sbjct: 529 PHGTLSPDLNRSHPPEPPKKGLLQRLFKRQHQNNSKSSPNSKTSFNHHINS 579
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 31.2 bits (69), Expect = 2.3 Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%) Frame = +2 Query: 5 PPFYSDDPITTCRKIVHWRNHVKFPDDSRLSPEARDLICRLLC-DVDHRIGGAGA----D 169 PPF +++ KI + ++ F ++ +ARD+I + L + R+G G D Sbjct: 287 PPFTANNHKRIMEKITRAKPNIPF----YVTSDARDIINKFLKKNPKQRLGADGPEKGYD 342 Query: 170 QIKAHPWFRGVAWDKLYE--MEAAFKPQVNDELDTQNF-MKFDE--MDNSPPARRGSGPS 334 IK H +R + W+KL + + P + + +NF ++F + + +P G Sbjct: 343 AIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPEAAENFSVEFTKLPLSTTPILHEEFG-- 400 Query: 335 RKAKLNSKDLSFVGYTY 385 + S +F G+TY Sbjct: 401 -NLTIGSHSSAFQGFTY 416 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 98,503,701 Number of Sequences: 219361 Number of extensions: 2207767 Number of successful extensions: 5949 Number of sequences better than 10.0: 281 Number of HSP's better than 10.0 without gapping: 5668 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5831 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4986986160 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
