ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags19c07 |
|---|---|
| Clone Library Name | barley_pub |
>ALDH_LINUS (Q40255) Probable aldehyde dehydrogenase (EC 1.2.1.3)| (Flax-inducible sequence 1) Length = 551 Score = 363 bits (932), Expect = e-100 Identities = 168/211 (79%), Positives = 194/211 (91%) Frame = +1 Query: 13 GKXVGQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQM 192 G +GQ SNG+RWPFGPVAIITPFNFPLEIP+LQLMGALYMGNKP+LKVDSKVSIVMEQM Sbjct: 179 GNHLGQQSNGFRWPFGPVAIITPFNFPLEIPVLQLMGALYMGNKPLLKVDSKVSIVMEQM 238 Query: 193 IRLLHECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLED 372 +RLLH CGLP D DF+NSDG MNK+LLEANP+MTLFTGSSRVAEKLA DL+GRIKLED Sbjct: 239 MRLLHYCGLPVGDADFVNSDGKAMNKILLEANPRMTLFTGSSRVAEKLALDLKGRIKLED 298 Query: 373 AGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSE 552 AGFDWKILGPDV E DY++WVCDQDAYACSGQKCSAQS+LFMH+NW+++ L+ ++K+L+E Sbjct: 299 AGFDWKILGPDVNEADYVAWVCDQDAYACSGQKCSAQSILFMHENWAATPLISRLKELAE 358 Query: 553 RRKLEDLTIGPVLTVTTSTMIEHMNNLLKIP 645 RRKLEDLT+GPVLTVTT M++H+N LL+IP Sbjct: 359 RRKLEDLTVGPVLTVTTEAMLDHLNKLLQIP 389
>ALDH1_BACSU (P42236) Probable aldehyde dehydrogenase ycbD (EC 1.2.1.3)| Length = 488 Score = 76.6 bits (187), Expect = 6e-14 Identities = 59/187 (31%), Positives = 101/187 (54%), Gaps = 5/187 (2%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G V +I+P+NFP+ IP+ ++ AL GN V+K ++ ++ ++I E GLPA Sbjct: 144 RVPLGVVGVISPWNFPVAIPIWKMAPALVYGNTVVIKPATETAVTCAKIIACFEEAGLPA 203 Query: 226 EDVDFINSDGITMNKLLLEAN-PKMTLFTGSSRVAEKL--AADLQG-RIKLEDAGFDWKI 393 ++ + G + + L E + FTGS++V + + AA +G + +LE G + I Sbjct: 204 GVINLVTGPGSVVGQGLAEHDGVNAVTFTGSNQVGKIIGQAALARGAKYQLEMGGKNPVI 263 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMK-KLSERRKLED 570 + D +++ + A+ +GQKC+A S + + SG+ E+ K KL +R K D Sbjct: 264 VADDA-DLEAAAEAVITGAFRSTGQKCTATSRVIV-----QSGIYERFKEKLLQRTK--D 315 Query: 571 LTIGPVL 591 +TIG L Sbjct: 316 ITIGDSL 322
>ALDH_BACST (P42329) Aldehyde dehydrogenase, thermostable (EC 1.2.1.3)| Length = 488 Score = 69.3 bits (168), Expect = 9e-12 Identities = 55/189 (29%), Positives = 96/189 (50%), Gaps = 9/189 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G V +I+P+NFP+ IP+ ++ AL GN VLK S+ ++ ++I HE G P Sbjct: 144 RVPLGVVGVISPWNFPVAIPIWKMAPALVYGNTVVLKPASETAVTAAKVIECFHEAGFPK 203 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKL---AADLQGRIKLEDAGFDWK 390 V+ + G + + + +P + FTGS+ V +++ A + + +LE G + Sbjct: 204 GVVNMVCGSGSVVGQGIAN-HPDIDGVTFTGSNTVGKQVGRAAFERGAKYQLEMGGKNPV 262 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNW---SSSGLLEKMKKLSERRK 561 I+ D ++D +GQKC+A S +F+ + + LLE++K+L Sbjct: 263 IVAKDA-DLDLAVEGTISGGLRSTGQKCTATSRVFIEREVYEPFKAKLLERVKQLKIGNG 321 Query: 562 LEDLT-IGP 585 L+ T +GP Sbjct: 322 LDAETWMGP 330
>ROCA1_BACHD (Q9K9B2) 1-pyrroline-5-carboxylate dehydrogenase 1 (EC 1.5.1.12)| (P5C dehydrogenase 1) Length = 515 Score = 69.3 bits (168), Expect = 9e-12 Identities = 59/205 (28%), Positives = 99/205 (48%), Gaps = 16/205 (7%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + P G I+P+NF L I + + + GN VLK S +V + + +L Sbjct: 162 GEQNRYFYTPMGVTVTISPWNFALAIMVGTAVAPIVTGNTVVLKPASTTPVVAAKFVEVL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEANPKMTL--FTGSS----RVAEKLAADLQG---- 354 + GLP ++++ G + L++ +PK +L FTGS R+ E+ A G Sbjct: 222 EDAGLPKGVINYVPGSGAEVGDYLVD-HPKTSLITFTGSKDVGVRLYERAAVVRPGQNHL 280 Query: 355 -RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLE 531 R+ +E G D ++ D ++D + A+ SGQKCSA S +HK+ +LE Sbjct: 281 KRVIVEMGGKDTVVVDRDA-DLDLAAESILVSAFGFSGQKCSAGSRAVIHKDVYDE-VLE 338 Query: 532 KMKKLSERRKLEDLT-----IGPVL 591 K L++ + D T +GPV+ Sbjct: 339 KTVALAKNLTVGDPTNRDNYMGPVI 363
>ROCA2_BACHD (Q9K5Z5) 1-pyrroline-5-carboxylate dehydrogenase 2 (EC 1.5.1.12)| (P5C dehydrogenase 2) Length = 515 Score = 67.4 bits (163), Expect = 3e-11 Identities = 59/205 (28%), Positives = 99/205 (48%), Gaps = 16/205 (7%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + P G I+P+NF L I + + GN +LK S +V + + +L Sbjct: 162 GEHNRYFYTPIGVCVTISPWNFALAIMAGTTVAPIVTGNTVLLKPASTTPVVAAKFVEVL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEANPKMTL--FTGSS----RVAEKLAADLQG---- 354 E GLP V+F+ G + L++ +PK +L FTGS R+ E+ A G Sbjct: 222 EEAGLPKGVVNFVPGSGTDIGDYLID-HPKTSLITFTGSRDVGVRLYERAAVVHPGQQHL 280 Query: 355 -RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLE 531 R+ +E G D ++ D ++D + A+ SGQKCSA S +H++ +LE Sbjct: 281 KRVIVEMGGKDTVVVDKDA-DLDLAAQSIVTSAFGFSGQKCSAGSRAVIHQD-VYDVVLE 338 Query: 532 KMKKLSERRKL-----EDLTIGPVL 591 K L+++ + D+ +GPV+ Sbjct: 339 KAVALTKQLSVGEPTAPDVYMGPVV 363
>PUTA_RHIME (P95629) Bifunctional protein putA [Includes: Proline dehydrogenase| (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)] Length = 1224 Score = 66.6 bits (161), Expect = 6e-11 Identities = 45/161 (27%), Positives = 75/161 (46%), Gaps = 9/161 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P GP+ I+P+NFPL I Q+ AL GN + K + ++ + +R+L E G+PA Sbjct: 687 PLGPIVCISPWNFPLAIFTGQIAAALVAGNPVLAKPAEETPLIAAEGVRILREAGIPASA 746 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---------LEDAGFD 384 + + DG + L+ +FTGS+ VA + A L R+ E G + Sbjct: 747 LQLLPGDG-RVGAALVAGRDAGVMFTGSTEVARLIQAQLADRLSPAGRPVPLIAETGGQN 805 Query: 385 WKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 I+ + V A+ +GQ+CSA +L + ++ Sbjct: 806 AMIVDSSALAGQVVGDVI-TSAFDSAGQRCSALRVLCLQED 845
>PUTA_SALTY (P10503) Bifunctional protein putA [Includes: Proline dehydrogenase| (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)] Length = 1320 Score = 66.2 bits (160), Expect = 8e-11 Identities = 62/218 (28%), Positives = 94/218 (43%), Gaps = 14/218 (6%) Frame = +1 Query: 7 HEGKXVGQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVME 186 + G+ N P GPV I+P+NFPL I Q+ AL GN + K + S++ Sbjct: 753 YAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTSLIAA 812 Query: 187 QMIRLLHECGLPAEDVDFINSDGITMN-KLLLEANPKMTLFTGSSRVAEKL------AAD 345 Q I +L E G+P V + G T+ +L +A + +FTGS+ VA L D Sbjct: 813 QGIAILLEAGVPPGVVQLLPGRGETVGAQLTADARVRGVMFTGSTEVATLLQRNIATRLD 872 Query: 346 LQGR---IKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS 516 QGR + E G + I+ + V A+ +GQ+CSA +L + + + Sbjct: 873 AQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVL-ASAFDSAGQRCSALRVLCLQDDIAE 931 Query: 517 SGLLEKMKKLSERRKLE----DLTIGPVLTVTTSTMIE 618 L ++E R IGPV+ IE Sbjct: 932 HTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIE 969
>ROCA_BACSU (P39634) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 515 Score = 65.5 bits (158), Expect = 1e-10 Identities = 49/171 (28%), Positives = 81/171 (47%), Gaps = 10/171 (5%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+++ + G +I+PFNFPL I + A+ GN +LK +V + + ++ Sbjct: 162 GEVNQYHYEALGVGIVISPFNFPLAIMAGTAVAAIVTGNTILLKPADAAPVVAAKFVEVM 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP +++I DG + L+E + FTGS R+ E+ A G Sbjct: 222 EEAGLPNGVLNYIPGDGAEIGDFLVEHPKTRFVSFTGSRAVGCRIYERAAKVQPGQKWLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 R+ E G D ++ D ++D + A+ SGQKCSA S +H++ Sbjct: 282 RVIAEMGGKDTVLVDKDA-DLDLAASSIVYSAFGYSGQKCSAGSRAVIHQD 331
>ROCA_BACLD (Q65NN2) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 516 Score = 64.3 bits (155), Expect = 3e-10 Identities = 53/196 (27%), Positives = 96/196 (48%), Gaps = 16/196 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G +I P+NF I + + GN VLK S ++ + + +L E GLP Sbjct: 172 PTGVTVVIPPWNFLFAIMAGTTVAPIVTGNTVVLKPASAAPVIAAKFVEVLEESGLPKGV 231 Query: 232 VDFINSDGITMNKLLLEANPKMTL--FTGS----SRVAEKLAADLQGRIKL-----EDAG 378 V+F+ G + L++ +PK ++ FTGS +R+ E+ A G+ L E G Sbjct: 232 VNFVPGSGAEVGDYLVD-HPKTSIITFTGSREVGTRIFERAAKVQPGQTHLKQVIAEMGG 290 Query: 379 FDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 D ++ D +++ + A+ +GQKCSA S +H+ +L+++ +++E + Sbjct: 291 KDTVVVDEDC-DIELAAQSIFTSAFGFAGQKCSAGSRAVVHEKVYDE-VLKRVIEITESK 348 Query: 559 KL-----EDLTIGPVL 591 K+ D+ +GPV+ Sbjct: 349 KVGEPDSADVYMGPVI 364
>ROCA_BACCR (Q81IP0) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 515 Score = 63.9 bits (154), Expect = 4e-10 Identities = 50/162 (30%), Positives = 78/162 (48%), Gaps = 10/162 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II+P+NFP I AL GN +LK S +V + + +L E GLPA Sbjct: 171 PLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGV 230 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSS----RVAEKLAADLQGRIKL-----EDAGF 381 V+F+ +G + L++ + FTGS R+ E+ A G+I L E G Sbjct: 231 VNFVPGNGSEVGDYLVDHPRTRFVSFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGK 290 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 D ++ + +++ + A+ SGQKCSA S +H++ Sbjct: 291 DTIVVDKEA-DLELAAKSIVASAFGFSGQKCSACSRAVIHED 331
>ROCA2_BACSU (P94391) 1-pyrroline-5-carboxylate dehydrogenase 2 (EC 1.5.1.12)| (P5C dehydrogenase 2) Length = 515 Score = 63.9 bits (154), Expect = 4e-10 Identities = 54/196 (27%), Positives = 94/196 (47%), Gaps = 16/196 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G +I P+NF I + + GN VLK S ++ + + +L E GLP Sbjct: 171 PTGVTVVIPPWNFLFAIMAGTTVAPIVTGNTVVLKPASATPVIAAKFVEVLEESGLPKGV 230 Query: 232 VDFINSDGITMNKLLLEANPKMTL--FTGSSRVAEKL---AADLQ------GRIKLEDAG 378 V+F+ G + L++ +PK +L FTGS V ++ AA +Q R+ E G Sbjct: 231 VNFVPGSGSEVGDYLVD-HPKTSLITFTGSREVGTRIFERAAKVQPGQQHLKRVIAEMGG 289 Query: 379 FDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 D ++ D +++ + A+ +GQKCSA S +H+ +LE++ +++E + Sbjct: 290 KDTVVVDEDA-DIELAAQSIFTSAFGFAGQKCSAGSRAVVHEKVYDQ-VLERVIEITESK 347 Query: 559 -----KLEDLTIGPVL 591 D+ +GPV+ Sbjct: 348 VTAKPDSADVYMGPVI 363
>ROCA_BACHK (Q6HP91) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 515 Score = 63.5 bits (153), Expect = 5e-10 Identities = 50/162 (30%), Positives = 78/162 (48%), Gaps = 10/162 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II+P+NFP I AL GN +LK S +V + + +L E GLPA Sbjct: 171 PLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGV 230 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSS----RVAEKLAADLQGRIKL-----EDAGF 381 V+F+ +G + L++ + FTGS R+ E+ A G+I L E G Sbjct: 231 VNFVPGNGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGK 290 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 D ++ + +++ + A+ SGQKCSA S +H++ Sbjct: 291 DTIVVDKEA-DLELAAKSIVASAFGFSGQKCSACSRAVIHED 331
>ROCA_BACCZ (Q63GS0) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 515 Score = 63.5 bits (153), Expect = 5e-10 Identities = 50/162 (30%), Positives = 78/162 (48%), Gaps = 10/162 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II+P+NFP I AL GN +LK S +V + + +L E GLPA Sbjct: 171 PLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGV 230 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSS----RVAEKLAADLQGRIKL-----EDAGF 381 V+F+ +G + L++ + FTGS R+ E+ A G+I L E G Sbjct: 231 VNFVPGNGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGK 290 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 D ++ + +++ + A+ SGQKCSA S +H++ Sbjct: 291 DTIVVDKEA-DLELAAKSIVASAFGFSGQKCSACSRAVIHED 331
>ROCA_BACAN (Q81ZF8) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 515 Score = 63.5 bits (153), Expect = 5e-10 Identities = 50/162 (30%), Positives = 78/162 (48%), Gaps = 10/162 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II+P+NFP I AL GN +LK S +V + + +L E GLPA Sbjct: 171 PLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGV 230 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSS----RVAEKLAADLQGRIKL-----EDAGF 381 V+F+ +G + L++ + FTGS R+ E+ A G+I L E G Sbjct: 231 VNFVPGNGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGK 290 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 D ++ + +++ + A+ SGQKCSA S +H++ Sbjct: 291 DTIVVDKEA-DLELAAKSIVASAFGFSGQKCSACSRAVIHED 331
>MMSA_BACSU (P42412) Probable methylmalonate-semialdehyde dehydrogenase| [acylating] (EC 1.2.1.27) (MMSDH) Length = 487 Score = 63.5 bits (153), Expect = 5e-10 Identities = 48/183 (26%), Positives = 86/183 (46%), Gaps = 3/183 (1%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR+P G V I PFNFP+ +P A+ +GN +LK + ++ E+++ L + GLP Sbjct: 139 YRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPSERTPLLTEKLVELFEKAGLP 198 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAE---KLAADLQGRIKLEDAGFDWKI 393 + + +N +L K F GS V E K ++ R++ + I Sbjct: 199 KGVFNVVYGAHDVVNGILEHPEIKAISFVGSKPVGEYVYKKGSENLKRVQSLTGAKNHTI 258 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLEDL 573 + D D ++ + A+ +G++C A +++ + + + E M KL E K+ D+ Sbjct: 259 VLNDANLEDTVTNIVGA-AFGSAGERCMACAVVTVEEGIAD----EFMAKLQE--KVADI 311 Query: 574 TIG 582 IG Sbjct: 312 KIG 314
>BADH_BETVU (P28237) Betaine-aldehyde dehydrogenase, chloroplast precursor (EC| 1.2.1.8) (BADH) Length = 500 Score = 63.2 bits (152), Expect = 7e-10 Identities = 57/197 (28%), Positives = 93/197 (47%), Gaps = 10/197 (5%) Frame = +1 Query: 34 SNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHEC 213 S+ R P G V +ITP+N+PL + ++ AL G VLK SI + + +E Sbjct: 145 SHVLRQPIGVVGLITPWNYPLLMATWKIAPALAAGCTAVLKPSELASITCLEFGEVCNEV 204 Query: 214 GLPAEDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKL---AADLQGRIKLEDAG 378 GLP ++ + G L A+P + FTGSS K+ AA L + LE G Sbjct: 205 GLPPGVLNIVTGLGPDAG-APLAAHPDVDKVAFTGSSATGSKVMASAAQLVKPVTLELGG 263 Query: 379 FDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 I+ DV + W + +GQ CSA S L +H++ ++ ++++ K ++ Sbjct: 264 KSPIIVFEDVDIDQVVEWTM-FGCFWTNGQICSATSRLLVHESIAAE-FIDRLVKWTKNI 321 Query: 559 KLED-----LTIGPVLT 594 K+ D +GPV++ Sbjct: 322 KISDPFEEGCRLGPVIS 338
>ROCA_BACC1 (P62028) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 515 Score = 63.2 bits (152), Expect = 7e-10 Identities = 50/162 (30%), Positives = 77/162 (47%), Gaps = 10/162 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II+P+NFP I AL GN +LK S +V + + +L E GLPA Sbjct: 171 PLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGV 230 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSS----RVAEKLAADLQGRIKL-----EDAGF 381 V+F+ G + L++ + FTGS R+ E+ A G+I L E G Sbjct: 231 VNFVPGSGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGK 290 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 D ++ + +++ + A+ SGQKCSA S +H++ Sbjct: 291 DTIVVDKEA-DLELAAKSIVASAFGFSGQKCSACSRAVIHED 331
>ROCA_STAES (Q8CN04) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 63.2 bits (152), Expect = 7e-10 Identities = 55/203 (27%), Positives = 95/203 (46%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + P G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNRYFYKPIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTVLTAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPQGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQQFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ +V + D + A+ SGQKCSA S +H++ +LEK Sbjct: 282 RVIAEMGGKDAIVVDNNV-DTDLAAEAIVTSAFGFSGQKCSACSRAIVHQDVHDE-ILEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 +L+++ L E+ +GPV+ Sbjct: 340 AIQLTQKLTLGNTEENTFMGPVI 362
>ROCA_STAEQ (Q5HL59) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 63.2 bits (152), Expect = 7e-10 Identities = 55/203 (27%), Positives = 95/203 (46%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + P G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNRYFYKPIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTVLTAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPQGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQQFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ +V + D + A+ SGQKCSA S +H++ +LEK Sbjct: 282 RVIAEMGGKDAIVVDNNV-DTDLAAEAIVTSAFGFSGQKCSACSRAIVHQDVHDE-ILEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 +L+++ L E+ +GPV+ Sbjct: 340 AIQLTQKLTLGNTEENTFMGPVI 362
>PUTA_KLEAE (O52485) Bifunctional protein putA [Includes: Proline dehydrogenase| (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)] Length = 1312 Score = 62.8 bits (151), Expect = 9e-10 Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 14/218 (6%) Frame = +1 Query: 7 HEGKXVGQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVME 186 + G+ N P GPV I+P+NFPL I Q+ AL GN + K + ++ Sbjct: 753 YAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAA 812 Query: 187 QMIRLLHECGLPAEDVDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQGRIK 363 Q + +L E G+P + + G T+ L + + +FTGS+ VA L ++ R+ Sbjct: 813 QGVAILLEAGVPPGVIQLLPGRGETVGAALTSDERVRGVMFTGSTEVATLLQRNIASRLD 872 Query: 364 ---------LEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS 516 E G + I+ + V A+ +GQ+CSA +L + + + Sbjct: 873 PQGRPTPLIAETGGMNAMIVDSSALTEQVVIDVL-ASAFDSAGQRCSALRVLCLQEEVAD 931 Query: 517 SGLLEKMKKLSERRKLE----DLTIGPVLTVTTSTMIE 618 L +SE R IGPV+ IE Sbjct: 932 HTLTMLRGAMSECRMGNPGRLTTDIGPVIDAEAKENIE 969
>ROCA_STAS1 (Q4A0E7) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 62.0 bits (149), Expect = 1e-09 Identities = 54/196 (27%), Positives = 90/196 (45%), Gaps = 10/196 (5%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + P G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNKYFYKPIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPLTAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEA-NPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L+++ + FTGS +R+ E+ A G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDSVHTHFVTFTGSRATGTRIFERAAKVQDGQQFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ D+ + D + A+ SGQKCSA S +HK+ +LEK Sbjct: 282 RVIAEMGGKDAIVVDKDI-DTDLAAESIVSSAFGFSGQKCSACSRAIVHKDVYDE-VLEK 339 Query: 535 MKKLSERRKLEDLTIG 582 L+ ++LT+G Sbjct: 340 AVALT-----KNLTVG 350
>ASTD_ECOLI (P76217) Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.-)| Length = 492 Score = 60.8 bits (146), Expect = 3e-09 Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 3/171 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G +A+ P+NFP +P ++ AL GN + K E ++RL + GLP Sbjct: 134 PHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGV 193 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQG---RIKLEDAGFDWKILGP 402 ++ + T L + LFTGS+ +L L G +I + G + ++ Sbjct: 194 LNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIID 253 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSER 555 +V ++D + Q A+ +GQ+C+ L + L ++ +S+R Sbjct: 254 EVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQR 304
>ALDH3_YEAST (P54114) Aldehyde dehydrogenase [NAD(P)+] 2 (EC 1.2.1.5)| Length = 506 Score = 60.8 bits (146), Expect = 3e-09 Identities = 56/197 (28%), Positives = 90/197 (45%), Gaps = 14/197 (7%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 PFG VA I P+N+PL + ++ GAL GN ++K S+ + L+ + G P Sbjct: 158 PFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGV 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRV-AEKLAADLQGRIK---LEDAGFDWKIL 396 V+ I G + K L + FTGS++V L A Q +K LE G ++ Sbjct: 218 VNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALV 277 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR-----K 561 D I WV + + SGQ C+A S +++ + +EK K+ +++ K Sbjct: 278 FEDADLDKAIEWVAN-GIFFNSGQICTANSRVYVQSSIYDK-FVEKFKETAKKEWDVAGK 335 Query: 562 L----EDLTIGPVLTVT 600 E +GPV++ T Sbjct: 336 FDPFDEKCIVGPVISST 352
>PUTA_ECOLI (P09546) Bifunctional protein putA [Includes: Proline dehydrogenase| (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)] Length = 1320 Score = 60.8 bits (146), Expect = 3e-09 Identities = 60/218 (27%), Positives = 92/218 (42%), Gaps = 14/218 (6%) Frame = +1 Query: 7 HEGKXVGQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVME 186 + G+ +N P GPV I+P+NFPL I Q+ AL GN + K + ++ Sbjct: 753 YAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAA 812 Query: 187 QMIRLLHECGLPAEDVDFINSDGITMN-KLLLEANPKMTLFTGSSRVAEKL------AAD 345 Q I +L E G+P V + G T+ +L + + +FTGS+ VA L D Sbjct: 813 QGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLD 872 Query: 346 LQGR---IKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS 516 QGR + E G + I+ + V A+ +GQ+CSA +L + + Sbjct: 873 AQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVL-ASAFDSAGQRCSALRVLCLQDEIAD 931 Query: 517 SGLLEKMKKLSERRKLE----DLTIGPVLTVTTSTMIE 618 L ++E R IGPV+ IE Sbjct: 932 HTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIE 969
>BADH_ATRHO (P42757) Betaine-aldehyde dehydrogenase, chloroplast precursor (EC| 1.2.1.8) (BADH) Length = 502 Score = 60.8 bits (146), Expect = 3e-09 Identities = 52/196 (26%), Positives = 91/196 (46%), Gaps = 9/196 (4%) Frame = +1 Query: 34 SNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHEC 213 S+ R P G V +I+P+N+PL + ++ AL G VLK S+ + + +E Sbjct: 147 SHVLRQPIGVVGLISPWNYPLLMDTWKIAPALAAGCTTVLKPSELASVTCLEFGEVCNEV 206 Query: 214 GLPAEDVDFINSDGITMN-KLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGF 381 GLP ++ + G ++ + FTGSS K+ AA L + LE G Sbjct: 207 GLPPGVLNILTGLGPDAGAPIVSHPDIDKVAFTGSSATGSKIMASAAQLVKPVTLELGGK 266 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRK 561 I+ D+ + W + +GQ CSA S L +H++ ++ +++M K ++ K Sbjct: 267 SPVIMFEDIDIETAVEWTL-FGVFWTNGQICSATSRLLVHESIAAE-FVDRMVKWTKNIK 324 Query: 562 LED-----LTIGPVLT 594 + D +GPV++ Sbjct: 325 ISDPFEEGCRLGPVIS 340
>ROCA_STAAW (Q8NUR2) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 60.5 bits (145), Expect = 4e-09 Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ ++ + D + A+ SGQKCSA S +HK+ +LEK Sbjct: 282 RVIAEMGGKDAIVVDENI-DTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDE-VLEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 KL++ L ++ +GPV+ Sbjct: 340 SIKLTKELTLGNTVDNTYMGPVI 362
>ROCA_STAAR (Q6GDP4) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 60.5 bits (145), Expect = 4e-09 Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ ++ + D + A+ SGQKCSA S +HK+ +LEK Sbjct: 282 RVIAEMGGKDAIVVDENI-DTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDE-VLEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 KL++ L ++ +GPV+ Sbjct: 340 SIKLTKELTLGNTVDNTYMGPVI 362
>ROCA_STAAN (P99076) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 60.5 bits (145), Expect = 4e-09 Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ ++ + D + A+ SGQKCSA S +HK+ +LEK Sbjct: 282 RVIAEMGGKDAIVVDENI-DTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDE-VLEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 KL++ L ++ +GPV+ Sbjct: 340 SIKLTKELTLGNTVDNTYMGPVI 362
>ROCA_STAAM (P63939) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 60.5 bits (145), Expect = 4e-09 Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ ++ + D + A+ SGQKCSA S +HK+ +LEK Sbjct: 282 RVIAEMGGKDAIVVDENI-DTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDE-VLEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 KL++ L ++ +GPV+ Sbjct: 340 SIKLTKELTLGNTVDNTYMGPVI 362
>ROCA_STAAC (Q5HCZ6) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 60.5 bits (145), Expect = 4e-09 Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ ++ + D + A+ SGQKCSA S +HK+ +LEK Sbjct: 282 RVIAEMGGKDAIVVDENI-DTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDE-VLEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 KL++ L ++ +GPV+ Sbjct: 340 SIKLTKELTLGNTVDNTYMGPVI 362
>BADH_SPIOL (P17202) Betaine-aldehyde dehydrogenase, chloroplast precursor (EC| 1.2.1.8) (BADH) Length = 497 Score = 60.5 bits (145), Expect = 4e-09 Identities = 53/196 (27%), Positives = 91/196 (46%), Gaps = 9/196 (4%) Frame = +1 Query: 34 SNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHEC 213 S+ R P G V +I+P+N+PL + ++ AL G VLK S+ + + +E Sbjct: 142 SHVLRQPLGVVGLISPWNYPLLMATWKIAPALAAGCTAVLKPSELASVTCLEFGEVCNEV 201 Query: 214 GLPAEDVDFINSDGITMN-KLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGF 381 GLP ++ + G L+ + FTGSS K+ AA L + LE G Sbjct: 202 GLPPGVLNILTGLGPDAGAPLVSHPDVDKIAFTGSSATGSKVMASAAQLVKPVTLELGGK 261 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRK 561 ++ DV + W + +GQ CSA S L +H++ ++ ++K+ K ++ K Sbjct: 262 SPIVVFEDVDIDKVVEWTI-FGCFWTNGQICSATSRLLVHESIAAE-FVDKLVKWTKNIK 319 Query: 562 LED-----LTIGPVLT 594 + D +GPV++ Sbjct: 320 ISDPFEEGCRLGPVIS 335
>BADH_SCHPO (O59808) Probable betaine aldehyde dehydrogenase (EC 1.2.1.8)| (BADH) (Meiotic expression up-regulated protein 8) Length = 500 Score = 60.1 bits (144), Expect = 6e-09 Identities = 58/197 (29%), Positives = 94/197 (47%), Gaps = 12/197 (6%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R+P G + +ITP+NFPL++ L +L+ A+ GN VLK + + E GLP Sbjct: 160 RFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSELAPWSCLEFALICKEAGLPD 219 Query: 226 EDVDFINSDGITMNKLLLEANPKMT--LFTGSSRVAEKL---AADLQGRIKLEDAGFDWK 390 ++ I G + L +PK+ FTGS +K+ AA+ + LE G Sbjct: 220 GVLNVIIGSG-KESGAALSCHPKIAYLAFTGSLATGKKIMHAAAENIVPLTLELGGKSPL 278 Query: 391 ILGPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSE 552 I+ D +S A+A G+ C+A S L +H++ + GL+ + KL Sbjct: 279 IICEDAD----LSLAIPSAAFAIFFNQGEACTAASRLIVHESVADEVLGGLVSEANKLII 334 Query: 553 RRKLE-DLTIGPVLTVT 600 L+ +T+GPV++ T Sbjct: 335 GNGLDPQVTLGPVVSKT 351
>ALDH_ENCBU (Q27640) Aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde| dehydrogenase [NAD+]) Length = 497 Score = 59.7 bits (143), Expect = 7e-09 Identities = 48/160 (30%), Positives = 73/160 (45%), Gaps = 8/160 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V ITP+NFPL + ++ A+ G VLK + + + L+ + G PA Sbjct: 156 PVGVVGAITPWNFPLHLAASKIAPAIAAGCTLVLKPAEQTPLTALYLASLVKQAGFPAGV 215 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQG-------RIKLEDAGFDW 387 ++ + G T L + FTGS+ V + + +QG R+ LE G Sbjct: 216 INIVPGLGHTAGAALTNHPDINKITFTGSTEVGQLI---IQGSGKTNLKRVTLELGGKSP 272 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 I+ PD ++DY V Q A GQ C A S F+H++ Sbjct: 273 NIIFPD-SDLDYAVEVSHQAIMANMGQVCCAGSRTFVHED 311
>BADH_ARATH (Q9S795) Betaine-aldehyde dehydrogenase, chloroplast precursor (EC| 1.2.1.8) (BADH) Length = 501 Score = 59.3 bits (142), Expect = 9e-09 Identities = 52/190 (27%), Positives = 85/190 (44%), Gaps = 9/190 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +ITP+N+PL + + ++ +L G +LK S+ ++ + E GLP Sbjct: 151 PLGVVGLITPWNYPLLMAVWKVAPSLAAGCTAILKPSELASVTCLELADICREVGLPPGV 210 Query: 232 VDFINSDGITMN-KLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKILG 399 ++ + G L FTGS K+ AA L + +E G I+ Sbjct: 211 LNVLTGFGSEAGAPLASHPGVDKIAFTGSFATGSKVMTAAAQLVKPVSMELGGKSPLIVF 270 Query: 400 PDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED--- 570 DV W + +GQ CSA S L +H++ +S +EK+ K S+ K+ D Sbjct: 271 DDVDLDKAAEWAL-FGCFWTNGQICSATSRLLVHESIASE-FIEKLVKWSKNIKISDPME 328 Query: 571 --LTIGPVLT 594 +GPV++ Sbjct: 329 EGCRLGPVVS 338
>ALDH2_YEAST (P47771) Aldehyde dehydrogenase [NAD(P)+] 1 (EC 1.2.1.5)| Length = 506 Score = 59.3 bits (142), Expect = 9e-09 Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 14/197 (7%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 PFG VA I P+N+PL + +L GAL GN ++K S+ + L+ + G P Sbjct: 158 PFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGV 217 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAE-KLAADLQGRIK---LEDAGFDWKIL 396 V+ + G + + L + FTGS++V L A Q +K LE G ++ Sbjct: 218 VNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALV 277 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR-----K 561 D I W+ Y SGQ C+A S +++ + +EK K+ +++ K Sbjct: 278 FEDADLDKAIDWIAAGIFYN-SGQNCTANSRVYVQSSIYDK-FVEKFKETAKKEWDVAGK 335 Query: 562 L----EDLTIGPVLTVT 600 E +GPV++ T Sbjct: 336 FDPFDEKCIVGPVISST 352
>GAPN_PEA (P81406) NADP-dependent glyceraldehyde-3-phosphate dehydrogenase| (EC 1.2.1.9) (Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase) (Glyceraldehyde-3-phosphate dehydrogenase [NADP+]) (Triosephosphate dehydrogenase) Length = 496 Score = 59.3 bits (142), Expect = 9e-09 Identities = 48/198 (24%), Positives = 92/198 (46%), Gaps = 5/198 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G + I PFN+P+ + + ++ AL GN VLK ++ ++ M+ H G P Sbjct: 158 PLGVILAIPPFNYPVNLAVSKIAPALIAGNSIVLKPPTQGAVAALHMVHCFHLAGFPKGL 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 + + G + L + FTG +++E G D I+ D Sbjct: 218 ISCVTGKGSEIGDFLTMHPGVNCISFTGGDTGIAISKKSGMIPLQMELGGKDACIVLEDA 277 Query: 409 QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMK----KLSERRKLEDLT 576 ++D ++ + ++ SGQ+C+A ++ + ++ + L+EK+K KLS +D Sbjct: 278 -DLDLVAANIIKGGFSYSGQRCTAVKVVLVMES-VADALVEKVKVKVAKLSVGPPEDDSD 335 Query: 577 IGPVLTVTTSTMIEHMNN 630 I PV++ +++ IE + N Sbjct: 336 ITPVVSESSANFIEGLVN 353
>ROCA_STAAS (Q6G6C0) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 58.9 bits (141), Expect = 1e-08 Identities = 54/203 (26%), Positives = 93/203 (45%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + G I P+NFP I + + GN +LK + +++ +L Sbjct: 162 GEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNIVLLKPAEDTPYIAYKLMGIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLE-ANPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ ++ + D + A+ SGQKCSA S +HK+ +LEK Sbjct: 282 RVIAEMGGKDAIVVDENI-DTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDE-VLEK 339 Query: 535 MKKLSERRKL----EDLTIGPVL 591 KL++ L ++ +GPV+ Sbjct: 340 SIKLTKELTLGNTVDNTYMGPVI 362
>ASTD_PSEAE (O50174) Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.-)| Length = 488 Score = 58.9 bits (141), Expect = 1e-08 Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 3/169 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G VA+ P+NFP +P ++ AL GN V K V E ++ + GLPA Sbjct: 136 PHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFKPSELTPKVAELTLKAWIQAGLPAGV 195 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQG---RIKLEDAGFDWKILGP 402 ++ + T L FTGSSR L + G +I + G + ++ Sbjct: 196 LNLVQGGRETGVALAAHRGLDGLFFTGSSRTGNLLHSQFGGQPQKILALEMGGNNPLVVE 255 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLS 549 +V ++D + Q A+ +GQ+C+ L + + LL ++ +S Sbjct: 256 EVADLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDALLARLVAVS 304
>ROCA_STAHJ (Q4L966) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 514 Score = 58.5 bits (140), Expect = 2e-08 Identities = 53/203 (26%), Positives = 93/203 (45%), Gaps = 14/203 (6%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G+ + + G I P+NFP I + + GN +LK + ++I +L Sbjct: 162 GEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTVLTAYKLIEIL 221 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEA-NPKMTLFTGS----SRVAEKLAADLQG----- 354 E GLP V+F+ D + L+++ + FTGS +R+ E+ A +G Sbjct: 222 EEAGLPKGVVNFVPGDPKEIGDYLVDSVHTHFVTFTGSRATGTRIYERSAVVQEGQTFLK 281 Query: 355 RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK 534 R+ E G D ++ ++ + D + A+ SGQKCSA S +H + +LEK Sbjct: 282 RVIAEMGGKDAIVVDENI-DTDLAAESIITSAFGFSGQKCSACSRAIVHSSVYDE-VLEK 339 Query: 535 ----MKKLSERRKLEDLTIGPVL 591 K+L+ +++ +GPV+ Sbjct: 340 AVALTKELTVGNTVDNTFMGPVI 362
>BADH_AMAHP (O04895) Betaine-aldehyde dehydrogenase, chloroplast precursor (EC| 1.2.1.8) (BADH) Length = 501 Score = 58.5 bits (140), Expect = 2e-08 Identities = 52/193 (26%), Positives = 87/193 (45%), Gaps = 12/193 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +I+P+N+PL + ++ AL G VLK S+ ++ + E GLP Sbjct: 151 PIGVVGLISPWNYPLLMATWKVAPALAAGCSAVLKPSELASVTCLELAEVCREVGLPPGV 210 Query: 232 VDFINSDGITM-NKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKILG 399 ++ + G L + FTGS+ K+ AA L + LE G ++ Sbjct: 211 LNILTGLGPEAGGPLACHPDVDKVAFTGSTATGSKVMSSAAQLVKPVTLELGGKSPIVIF 270 Query: 400 PDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 DV W A+ C +GQ CSA S L +H++ ++ L+++ K + K+ D Sbjct: 271 EDVDLDKAAEWT----AFGCFWTNGQICSATSRLLVHESIAAE-FLDRLVKWCKNIKISD 325 Query: 571 -----LTIGPVLT 594 +GPV++ Sbjct: 326 PFEEGCRLGPVVS 338
>ROCA_OCEIH (Q8ERF4) 1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C| dehydrogenase) Length = 515 Score = 57.8 bits (138), Expect = 3e-08 Identities = 50/187 (26%), Positives = 85/187 (45%), Gaps = 10/187 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P GP +I P+NF I + + GN +LK ++ +++ +L E GLP Sbjct: 171 PLGPGVVIPPWNFAFAIVCGTTVAPIVAGNPVLLKPSENTPVIAYKLVEVLEEAGLPKGV 230 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSS----RVAEKLAADLQG-----RIKLEDAGF 381 ++F+ D + L++ + FTGS R+ E+ G RI E G Sbjct: 231 LNFVPGDPAEIGDYLVDHKDTHFINFTGSRATGVRIFERATKIQDGQTHLKRIVAEMGGK 290 Query: 382 DWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRK 561 D I+ + ++D + A+ SGQKCSA S +H++ ++EK +L+ Sbjct: 291 D-TIIVDESADLDLAAESIVHSAFGFSGQKCSACSRAVIHESVYDE-VIEKSVELA---- 344 Query: 562 LEDLTIG 582 + LT+G Sbjct: 345 -KTLTVG 350
>Y4UC_RHISN (Q53197) Hypothetical aldehyde-dehydrogenase-like protein y4uC (EC| 1.2.1.-) Length = 512 Score = 57.8 bits (138), Expect = 3e-08 Identities = 55/199 (27%), Positives = 85/199 (42%), Gaps = 16/199 (8%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G + ITP+N PL + +L A+ GN +LK + +++ L E GLP Sbjct: 178 RDPLGIITAITPYNDPLNLVAHKLGPAIAGGNAVMLKPSNLTPFSAIKLVGALREAGLPE 237 Query: 226 EDVDFINSDGITMNKLLLEANPKMTLFTGS-------SRVA--EKLAADLQGR---IKLE 369 E + + D + ++ +M FTG SR A +KLA +L G I + Sbjct: 238 EVITISHGDRELVTAMIAAREVRMVSFTGGFATGEAISRAAGLKKLAMELGGNAPVIVMN 297 Query: 370 DAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKC-SAQSMLFMHKNWS--SSGLLEKMK 540 D FD + G C A+ +GQ C AQ +L + + + K Sbjct: 298 DCDFDKAVEG------------CVSGAFWAAGQNCIGAQRILIQSELYGRFRDAFVAATK 345 Query: 541 KLSERRKL-EDLTIGPVLT 594 KL L ED +GP+++ Sbjct: 346 KLKAGDPLQEDTDVGPMIS 364
>ALDH2_LEITA (Q25417) Aldehyde dehydrogenase, mitochondrial precursor (EC| 1.2.1.3) (ALDH class 2) (P51) Length = 498 Score = 57.0 bits (136), Expect = 5e-08 Identities = 47/178 (26%), Positives = 87/178 (48%), Gaps = 5/178 (2%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G I P+NFPL + +L AL MGN VLK + + ++ ++ E G P Sbjct: 153 RQPIGVCGQIIPWNFPLLMAAFKLSPALAMGNTVVLKPAEQTPLTAVRLGEMVMEAGYPD 212 Query: 226 EDVDFINSDGITM-NKLLLEANPKMTLFTGSSRVAE---KLAADLQ-GRIKLEDAGFDWK 390 ++ + G T +++ + FTGS+ V ++AA+ ++ LE G Sbjct: 213 GVLNILPGFGATAGSEIARHMDVDKIAFTGSTAVGHQVMQMAAETNLKKVSLELGGKSAL 272 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL 564 I+ D +++ + V Y +GQ C+A S +++H++ + +++K +E RK+ Sbjct: 273 IVCEDA-DLEEAAEVATTRVYFNTGQVCTASSRIYVHESVYDE-FVSRLRKNAEARKV 328
>MMSA_BOVIN (Q07536) Methylmalonate-semialdehyde dehydrogenase [acylating],| mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) Length = 537 Score = 56.2 bits (134), Expect = 8e-08 Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 6/174 (3%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR P G A I PFNFP IPL A+ GN ++K +V + +L + G P Sbjct: 174 YRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLFQDSGAP 233 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKI 393 ++ I+ +N + + K F GS++ E + + R++ + + Sbjct: 234 DGTLNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRHGKRVQANMGAKNHGV 293 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM---HKNWSSSGLLEKMKKL 546 + PD + + ++ + A+ +GQ+C A S + K W L+E+ KKL Sbjct: 294 VMPDANKENTLNQLVGA-AFGAAGQRCMALSTAILVGEAKKWLPE-LVERAKKL 345
>MMSA_ANOGA (Q7QC84) Probable methylmalonate-semialdehyde dehydrogenase| [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) Length = 521 Score = 56.2 bits (134), Expect = 8e-08 Identities = 48/201 (23%), Positives = 87/201 (43%), Gaps = 7/201 (3%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 Y P G A I PFNFP IPL A+ GN ++K +V ++ +L+E G P Sbjct: 159 YHLPLGVTAGIAPFNFPAMIPLWMFPVAITCGNTSIIKPSERVPGATMLLMEMLNEAGCP 218 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKI 393 V+ I+ +N + + + F GS + + + A R++ + + Sbjct: 219 PGVVNVIHGAHDAVNFVCDNPDIRAVSFVGSDQAGKYIYERAGRNGKRVQCNMGAKNHGV 278 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM---HKNWSSSGLLEKMKKLS-ERRK 561 + D + + ++ + A+ +GQ+C A S +NW L+E+ +KL Sbjct: 279 IMADANKENTLNQLAGA-AFGAAGQRCMALSTAVFVGEARNWIPD-LVERARKLKVNAGH 336 Query: 562 LEDLTIGPVLTVTTSTMIEHM 624 L +GPV++ + I + Sbjct: 337 LPGTDLGPVISPQSKQRINEL 357
>MMSA_RAT (Q02253) Methylmalonate-semialdehyde dehydrogenase [acylating],| mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) Length = 535 Score = 55.5 bits (132), Expect = 1e-07 Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 6/174 (3%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR P G A I PFNFP IPL A+ GN ++K +V + +LL + G P Sbjct: 172 YRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAP 231 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKI 393 ++ I+ +N + + K F GS++ E + + R++ + + Sbjct: 232 DGTLNIIHGQHEAVNFICDHPDIKAISFVGSNQAGEYIFERGSRNGKRVQANMGAKNHGV 291 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM---HKNWSSSGLLEKMKKL 546 + PD + + ++ + A+ +GQ+C A S + K W L+E+ K L Sbjct: 292 VMPDANKENTLNQLVGA-AFGAAGQRCMALSTAVLVGEAKKWLPE-LVERAKNL 343
>PUUC_ECOLI (P23883) Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC| 1.2.1.-) (Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase) Length = 495 Score = 55.5 bits (132), Expect = 1e-07 Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 5/159 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G +A I P+NFPL + +L AL GN +LK K + ++ L E GLP Sbjct: 155 REPVGVIAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPD 214 Query: 226 EDVDFINSDGITMNKLLLEANP-KMTLFTGSSRVAEKLAADL----QGRIKLEDAGFDWK 390 ++ + G + L N FTGS+R ++L D R+ LE G Sbjct: 215 GVLNVVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSAN 274 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 I+ D ++ + + GQ C A + L + ++ Sbjct: 275 IVFADCPDLQQAASATAAGIFYNQGQVCIAGTRLLLEES 313
>BADH_ORYSA (O24174) Betaine-aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 505 Score = 55.1 bits (131), Expect = 2e-07 Identities = 49/178 (27%), Positives = 84/178 (47%), Gaps = 5/178 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +ITP+N+PL + ++ AL G VLK S+ ++ + E GLP Sbjct: 153 PIGVVGLITPWNYPLLMATWKVAPALAAGCTAVLKPSELASLTCLELGGICAEIGLPPGV 212 Query: 232 VDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKIL 396 ++ I G T L ++P + FTGS+ +++ A+ + + LE G I+ Sbjct: 213 LNIITGLG-TEAGAPLASHPHVDKIAFTGSTETGKRIMITASQMVKPVSLELGGKSPLIV 271 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 DV + W +A +GQ CSA S L +H+ + L+++ ++ K+ D Sbjct: 272 FDDVDIDKAVEWAM-FGCFANAGQVCSATSRLLLHEK-IAKRFLDRLVAWAKSIKISD 327
>MMSA_HUMAN (Q02252) Methylmalonate-semialdehyde dehydrogenase [acylating],| mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) Length = 535 Score = 54.7 bits (130), Expect = 2e-07 Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 6/174 (3%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR P G A I PFNFP IPL A+ GN ++K +V + +LL + G P Sbjct: 172 YRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAP 231 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKI 393 ++ I+ +N + + K F GS++ E + + R++ + + Sbjct: 232 DGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGV 291 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM---HKNWSSSGLLEKMKKL 546 + PD + + ++ + A+ +GQ+C A S + K W L+E K L Sbjct: 292 VMPDANKENTLNQLVGA-AFGAAGQRCMALSTAVLVGEAKKWLPE-LVEHAKNL 343
>GAPN_NICPL (P93338) NADP-dependent glyceraldehyde-3-phosphate dehydrogenase| (EC 1.2.1.9) (Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase) (Glyceraldehyde-3-phosphate dehydrogenase [NADP+]) (Triosephosphate dehydrogenase) Length = 496 Score = 54.3 bits (129), Expect = 3e-07 Identities = 48/195 (24%), Positives = 93/195 (47%), Gaps = 6/195 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G + I PFN+P+ + + ++ AL GN VLK ++ ++ M+ H G P Sbjct: 158 PLGVILAIPPFNYPVNLAVSKIAPALIAGNSLVLKPPTQGAVACLHMVHCFHLAGFPKGL 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFT-GSSRVAEKLAADLQGRIKLEDAGFDWKILGPD 405 + + G + L + FT G + VA A + +++E G D I+ D Sbjct: 218 ISCVTGKGSEIGDFLTMHPGVHCISFTGGDTGVAISKKAGMI-PLQMELGGKDACIVLED 276 Query: 406 VQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMK----KLSERRKLEDL 573 ++D + + ++ SGQ+C+A ++ + ++ + L+EK+ KL+ +D Sbjct: 277 A-DLDLAAGSIVKGGFSYSGQRCTAVKVVLVMES-VADALVEKVNAKVAKLTVGPPEDDC 334 Query: 574 TIGPVLTVTTSTMIE 618 I PV++ +++ IE Sbjct: 335 DITPVVSESSANFIE 349
>XYLC_PSEPU (P43503) Benzaldehyde dehydrogenase [NAD+] (EC 1.2.1.28)| Length = 487 Score = 53.9 bits (128), Expect = 4e-07 Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 5/166 (3%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMI-RL 201 G+M+ R P G V +I P+NFPL + + + AL +GN +LK D + ++ +I + Sbjct: 136 GRMNLCQRVPVGVVGVIAPWNFPLFLAMRSVAPALALGNAVILKPDLQTAVTGGALIAEI 195 Query: 202 LHECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGR----IKLE 369 + G+P + + ++ + M FTGS++V +L + GR + LE Sbjct: 196 FSDAGMPDGVLHVLPGGADVGESMVANSGINMISFTGSTQVG-RLIGEKCGRMLKKVALE 254 Query: 370 DAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 G + I+ PD +S + GQ C A +H++ Sbjct: 255 LGGNNVHIVLPDADLEGAVSCAA-WGTFLHQGQVCMAAGRHLVHRD 299
>Y1411_METJA (Q58806) Hypothetical aldehyde-dehydrogenase-like protein MJ1411| (EC 1.2.1.-) Length = 463 Score = 53.9 bits (128), Expect = 4e-07 Identities = 49/201 (24%), Positives = 97/201 (48%), Gaps = 10/201 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRL----LHEC 213 R P G V ITPFNFPL + ++ A+ GN V SK +V ++ ++ L + Sbjct: 127 REPVGIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVCIELAKIIENALKKY 186 Query: 214 GLPAEDVDFINSDG-ITMNKLLLEANPKMTLFTGSSRVAEKLAADLQ-GRIKLEDAGFDW 387 +P + + G + +++++ M FTGSS+V E + +I LE G + Sbjct: 187 NVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKAGFKKIALELGGVNP 246 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGL---LEKMKKLSERR 558 I+ D ++ + + ++ +GQ C + M+ + ++ + + + K K L+ Sbjct: 247 NIVLKDADLNKAVNALI-KGSFIYAGQVCISVGMILVDESIADKFIEMFVNKAKVLNVGN 305 Query: 559 KLEDLT-IGPVLTVTTSTMIE 618 L++ T +GP+++V + +E Sbjct: 306 PLDEKTDVGPLISVEHAEWVE 326
>GAPN_MAIZE (Q43272) NADP-dependent glyceraldehyde-3-phosphate dehydrogenase| (EC 1.2.1.9) (Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase) (Glyceraldehyde-3-phosphate dehydrogenase [NADP+]) (Triosephosphate dehydrogenase) Length = 498 Score = 53.9 bits (128), Expect = 4e-07 Identities = 48/194 (24%), Positives = 91/194 (46%), Gaps = 5/194 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I PFN+P + ++ AL GN VLK ++ ++ M+ H G P Sbjct: 160 PLGVVLAIPPFNYPANLAGSKIGPALIAGNALVLKPPTQGAVAALHMVHCFHLAGFPKGL 219 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFT-GSSRVAEKLAADLQGRIKLEDAGFDWKILGPD 405 + + G + L + FT G + +A A + +++E G D I+ D Sbjct: 220 ISCVTGKGSEIGDFLTMHPGVNCISFTGGDTGIAISKKAGMV-PLQMELGGKDACIVLED 278 Query: 406 VQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLE---KMKKLSERRKLEDLT 576 ++D +S + ++ SGQ+C+A ++ + ++ + + + + K+ KL +D Sbjct: 279 A-DLDLVSANIVKGGFSYSGQRCTAVKVVLIMESIADAVVQKVNAKLAKLKVGPPEDDSD 337 Query: 577 IGPVLTVTTSTMIE 618 I PV+T +++ IE Sbjct: 338 ITPVVTESSANFIE 351
>GAPN_STRMU (Q59931) NADP-dependent glyceraldehyde-3-phosphate dehydrogenase| (EC 1.2.1.9) (Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase) (Glyceraldehyde-3-phosphate dehydrogenase [NADP+]) (Triosephosphate dehydrogenase) Length = 475 Score = 53.5 bits (127), Expect = 5e-07 Identities = 51/200 (25%), Positives = 91/200 (45%), Gaps = 5/200 (2%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G V I+PFN+P+ + ++ AL GN K ++ SI + E GLPA Sbjct: 141 REPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAFKPPTQGSISGLLLAEAFAEAGLPA 200 Query: 226 EDVDFINSDGITMNKLLLEANP-KMTLFTGSSRVAEKLAADLQGR-IKLEDAGFDWKILG 399 + I G + ++E FTGS+ + E++ R I LE G D I+ Sbjct: 201 GVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIGERIGKMAGMRPIMLELGGKDSAIVL 260 Query: 400 PDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSERRKLED 570 D +++ + A+ SGQ+C+A + + ++ + + EK+ L+ +D Sbjct: 261 EDA-DLELTAKNIIAGAFGYSGQRCTAVKRVLVMESVADELVEKIREKVLALTIGNPEDD 319 Query: 571 LTIGPVLTVTTSTMIEHMNN 630 I P++ ++ +E + N Sbjct: 320 ADITPLIDTKSADYVEGLIN 339
>AL1B1_HUMAN (P30837) Aldehyde dehydrogenase X, mitochondrial precursor (EC| 1.2.1.3) (ALDH class 2) Length = 517 Score = 53.5 bits (127), Expect = 5e-07 Identities = 48/174 (27%), Positives = 78/174 (44%), Gaps = 5/174 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + +L AL GN V+KV + + + L+ E G P Sbjct: 175 PVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGV 234 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSSRVA---EKLAADLQ-GRIKLEDAGFDWKIL 396 V+ I G T + + + FTGS+ V +K A D R+ LE G I+ Sbjct: 235 VNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIV 294 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 D ++++ C + + GQ C A S F+ ++ + L ++K +R+ Sbjct: 295 LADA-DMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRK 347
>BADH_HORVU (Q40024) Betaine-aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 505 Score = 53.5 bits (127), Expect = 5e-07 Identities = 46/178 (25%), Positives = 81/178 (45%), Gaps = 5/178 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +ITP+N+PL + ++ AL G VLK S+ ++ + E GLP+ Sbjct: 152 PIGVVGLITPWNYPLLMATWKVAPALAAGCTAVLKPSELASLTCLELGAICEEIGLPSGV 211 Query: 232 VDFINSDGITMN-KLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKILG 399 ++ I G + + FTGS+ + + AA + + LE G + Sbjct: 212 LNIITGLGPDAGAPIASHPHVDKIAFTGSTATGKTIMTAAAQMVKPVSLELGGKSPLVTF 271 Query: 400 PDVQEVD-YISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 DV ++D + W + GQ CSA S L +H+ + L+++ + ++ K+ D Sbjct: 272 DDVADIDKAVEWPM-LGCFFNGGQVCSATSRLLLHEK-IAEPFLDRLVEWAKNIKISD 327
>MMSA_CAEEL (P52713) Probable methylmalonate-semialdehyde dehydrogenase| [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) Length = 523 Score = 52.8 bits (125), Expect = 9e-07 Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 7/194 (3%) Frame = +1 Query: 34 SNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHEC 213 ++ YR P G A I PFNFP IPL AL GN V+K + + ++ L E Sbjct: 159 THSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEA 218 Query: 214 GLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFD 384 G+P V+ I+ +N + + K F G + + A R++ + Sbjct: 219 GVPDGCVNIIHGQHSAVNFICDNPDIKAISFVGGDAAGKHIYERGAKNGKRVQSNMGAKN 278 Query: 385 WKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM---HKNWSSSGLLEKMKKLSER 555 ++ D + ++ + A+ +GQ+C A + + + W L+EK K L Sbjct: 279 HGVIMADANKEQTLNQL-TAAAFGAAGQRCMALTTAVLVGEARAWLPE-LVEKAKNLKVN 336 Query: 556 RKLE-DLTIGPVLT 594 + D IGP+++ Sbjct: 337 AGWKPDTDIGPLIS 350
>FEAB_ECOLI (P80668) Phenylacetaldehyde dehydrogenase (EC 1.2.1.39) (PAD)| Length = 499 Score = 52.4 bits (124), Expect = 1e-06 Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 8/157 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G VA I P+NFPL I + ++M AL G V+K + M ++ L E G+P Sbjct: 163 PVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGIPDGV 222 Query: 232 VDFINSDGITMNKLLLEANPKMT--LFTGSSRVAE---KLAADLQGRIKLEDAGFDWKIL 396 + + G L ++P + FTGS+ + + AAD R+ LE G + I+ Sbjct: 223 FNVVTGSGAVCG-AALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGKNPAIV 281 Query: 397 GPDVQEVDYISWVCD---QDAYACSGQKCSAQSMLFM 498 D WV + ++ GQ C+A S +++ Sbjct: 282 LKDADP----QWVIEGLMTGSFLNQGQVCAASSRIYI 314
>AL1A3_RAT (Q8K4D8) Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde| dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) Length = 512 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 6/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G ITP+NFPL + +L AL GN VLK + + + L+ E G P Sbjct: 170 PIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGV 229 Query: 232 VDFINSDGITMNKLLLEANPKMT--LFTGSSRVAE--KLAADLQG--RIKLEDAGFDWKI 393 V+ + G T+ + ++P++ FTGS+ V + K AA R+ LE G + I Sbjct: 230 VNIVPGFGPTVG-AAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGRNPCI 288 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 + D ++D Q + GQ C+A S +F+ + Sbjct: 289 VCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324
>AL1A3_HUMAN (P47895) Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde| dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) Length = 512 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/157 (29%), Positives = 75/157 (47%), Gaps = 6/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G ITP+NFPL + + +L AL GN VLK + + + L+ E G P Sbjct: 170 PIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGV 229 Query: 232 VDFINSDGITMNKLLLEANPKMT--LFTGSSRVAE--KLAADLQG--RIKLEDAGFDWKI 393 V+ + G T+ + ++P++ FTGS+ V + K AA R+ LE G + I Sbjct: 230 VNIVPGFGPTVG-AAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCI 288 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 + D ++D Q + GQ C+A S +F+ + Sbjct: 289 VCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324
>AL1A3_MOUSE (Q9JHW9) Aldehyde dehydrogenase 1A3 (EC 1.2.1.5) (Aldehyde| dehydrogenase 6) (Retinaldehyde dehydrogenase 3) (RALDH-3) Length = 512 Score = 51.6 bits (122), Expect = 2e-06 Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 6/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G ITP+NFPL + +L AL GN VLK + + + L+ E G P Sbjct: 170 PIGVCGAITPWNFPLLMLAWKLAPALCCGNTVVLKPAEQTPLTALYLASLIKEVGFPPGV 229 Query: 232 VDFINSDGITMNKLLLEANPKMT--LFTGSSRVA----EKLAADLQGRIKLEDAGFDWKI 393 V+ + G T+ + ++P++ FTGS+ V E + R+ LE G + I Sbjct: 230 VNIVPGFGPTVG-AAISSHPQINKIAFTGSTEVGKLVREAASRSNLKRVTLELGGKNPCI 288 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 + D ++D Q + GQ C+A S +F+ + Sbjct: 289 VCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324
>BETB_BACSU (P71016) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 51.6 bits (122), Expect = 2e-06 Identities = 52/203 (25%), Positives = 88/203 (43%), Gaps = 12/203 (5%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G ITP+N+PL ++ AL GN V+K + ++ +L+ E G+P Sbjct: 138 REPIGVCGQITPWNYPLLQASWKIAPALAAGNTIVMKPSEITPLTTIKVFKLMEEAGVPK 197 Query: 226 EDVDFINSDGITM-NKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKI 393 + + G T+ ++L + + + FTG +K+ G +K LE G + I Sbjct: 198 GVANLVLGPGATVGDELAVNKDVDLISFTGGIETGKKIMRAASGNVKKIALELGGKNPNI 257 Query: 394 LGPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL 564 + D + DQ A +GQ CSA S L + L E +K+ ++R KL Sbjct: 258 VFKDAD----LEVAVDQALNAVFFHAGQVCSAGSRLLVEDAIHDQFLAELVKR-AKRIKL 312 Query: 565 -----EDLTIGPVLTVTTSTMIE 618 + GP+++ +E Sbjct: 313 GNGFHAETESGPLISAEHRAKVE 335
>MMSA_PSEAE (P28810) Methylmalonate-semialdehyde dehydrogenase [acylating] (EC| 1.2.1.27) (MMSDH) Length = 496 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 3/149 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G ITPFNFP IPL A+ GN +LK +V + ++ L E G P Sbjct: 139 PLGVCVGITPFNFPAMIPLWMFPLAIACGNAFILKPSEQVPLTSVRLAELFLEAGAPKGV 198 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKILGP 402 + ++ +++LL K F GS V + + R++ + ++ P Sbjct: 199 LQVVHGGKEQVDQLLKHPQVKAVSFVGSVAVGQYVYHTGTAHNKRVQSFAGAKNHMVIMP 258 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSM 489 D + IS + A +GQ+C A S+ Sbjct: 259 DADKAQVISNLVGASVGA-AGQRCMAISV 286
>MMSA_DROME (Q7KW39) Probable methylmalonate-semialdehyde dehydrogenase| [acylating], mitochondrial precursor (EC 1.2.1.27) (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) Length = 520 Score = 51.2 bits (121), Expect = 3e-06 Identities = 47/197 (23%), Positives = 84/197 (42%), Gaps = 6/197 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G A + PFNFP IPL A+ GN +LK +V ++ LL+E G P Sbjct: 161 PLGVTAGVAPFNFPAMIPLWMFPVAITTGNTMLLKPSERVPGATMLLMELLNEAGCPPGV 220 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWKILGP 402 V+ I+ +N + K F GS + + + A R++ + I+ Sbjct: 221 VNVIHGQHDAVNFICDAPEIKAVSFVGSDQAGKYIYERAGKNGKRVQSNMGAKNHGIILG 280 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS--SGLLEKMKKLS-ERRKLEDL 573 D + + ++ + A+ +GQ+C A S + + L+E+ +KL + Sbjct: 281 DANKENTLNQLAGA-AFGAAGQRCMALSTAVFVGDAQAWIPDLVERAQKLKVNAGHVPGT 339 Query: 574 TIGPVLTVTTSTMIEHM 624 +GPV++ + I + Sbjct: 340 DVGPVISAASRQRINDL 356
>ALDH2_BACSU (P39616) Probable aldehyde dehydrogenase ywdH (EC 1.2.1.3)| Length = 457 Score = 50.8 bits (120), Expect = 3e-06 Identities = 46/167 (27%), Positives = 77/167 (46%), Gaps = 3/167 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P+G V +I P+N+PL++ L L+GA+ GN VLK V + +L+ P + Sbjct: 105 PYGTVLVIAPWNYPLQLALSPLIGAIAAGNTVVLKPSEYTPAVSAILSKLISSV-FPTDY 163 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGS---SRVAEKLAADLQGRIKLEDAGFDWKILGP 402 V G ++ LL+ FTGS ++ + AA + LE G I+ Sbjct: 164 VAMAEG-GPDVSTALLQQPFDYIFFTGSVAVGKIVMEAAAKQLIPVTLELGGKSPCIVHK 222 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKK 543 D ++ + + +GQ C A LF+H++ + L E+MK+ Sbjct: 223 DA-DIQLAAKRIVFGKFTNAGQTCIAPDYLFVHEDIKTK-LTEEMKR 267
>ALDH5_YEAST (P40047) Aldehyde dehydrogenase, mitochondrial precursor (EC| 1.2.1.3) Length = 519 Score = 50.4 bits (119), Expect = 4e-06 Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 4/177 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ AL GN VLK + +L E G+PA Sbjct: 178 PLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGV 237 Query: 232 VDFINSDG-ITMNKLLLEANPKMTLFTGSS---RVAEKLAADLQGRIKLEDAGFDWKILG 399 V+ + G + +L + K FTGS+ R K+AAD ++ LE G I+ Sbjct: 238 VNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADTVKKVTLELGGKSPNIVF 297 Query: 400 PDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 D ++D + SG+ C A S +++ ++ +L+K+K +E K+ D Sbjct: 298 ADA-DLDKAVKNIAFGIFYNSGEVCCAGSRIYI-QDTVYEEVLQKLKDYTESLKVGD 352
>UGA2_YEAST (P38067) Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)| (SSDH) Length = 497 Score = 50.1 bits (118), Expect = 6e-06 Identities = 53/181 (29%), Positives = 77/181 (42%), Gaps = 10/181 (5%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G II P+NFP + + AL +G V+K DS+ + M L + G P Sbjct: 151 RQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAGFPK 210 Query: 226 EDVDFINSDGIT--MNKLLLEA-NPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKIL 396 + I S T + K L E+ K FTGS+ V + L Q L+ F+ L Sbjct: 211 GSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMK--QSSSTLKKLSFE---L 265 Query: 397 GPDVQEVDYISWVCDQ---DAYACS----GQKCSAQSMLFMHKNWSSSGLLEKMKKLSER 555 G + + + DQ A AC GQ C + L++H S +++K KL Sbjct: 266 GGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVH-----SSIIDKFAKLLAE 320 Query: 556 R 558 R Sbjct: 321 R 321
>ALDH2_MOUSE (P47738) Aldehyde dehydrogenase, mitochondrial precursor (EC| 1.2.1.3) (ALDH class 2) (AHD-M1) (ALDHI) (ALDH-E2) Length = 519 Score = 49.3 bits (116), Expect = 1e-05 Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 8/160 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + +L AL GN V+KV + + + L+ E G P Sbjct: 177 PVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGV 236 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAE--KLAADLQG--RIKLEDAGFDWKIL 396 V+ + G T + FTGS+ V ++AA R+ LE G I+ Sbjct: 237 VNIVPGFGPTAGAAIASHEGVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNII 296 Query: 397 GPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKN 507 D + W +Q +A GQ C A S F+ +N Sbjct: 297 MSDAD----MDWAVEQAHFALFFNQGQCCCAGSRTFVQEN 332
>BETB_AGRT5 (Q8UH56) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 493 Score = 48.9 bits (115), Expect = 1e-05 Identities = 49/185 (26%), Positives = 76/185 (41%), Gaps = 3/185 (1%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G + R P G I +N+P +I + AL GN V K + ++ +L Sbjct: 139 GDFAYTKRVPLGVCVGIGAWNYPQQIACWKAAPALVAGNAMVFKPSENTPLGALKIAEIL 198 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDA 375 E GLP + I D T L+ + TGS K+AA G +K +E Sbjct: 199 IEAGLPKGLFNVIQGDRDTGPLLVNHPDVAKVSLTGSVPTGRKVAAAAAGHLKHVTMELG 258 Query: 376 GFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSER 555 G I+ D + + Y+ SGQ CS + +F+ K + + LE +K+ +E Sbjct: 259 GKSPMIVFDDADIESAVGGAMLGNFYS-SGQVCSNGTRVFVQKK-AKARFLENLKRRTEA 316 Query: 556 RKLED 570 L D Sbjct: 317 MILGD 321
>BETB_PSESM (Q88AE9) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 48.9 bits (115), Expect = 1e-05 Identities = 47/206 (22%), Positives = 94/206 (45%), Gaps = 9/206 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K S+ ++ + E G+P Sbjct: 140 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGVPN 199 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGRIKLE---DAGFDWK 390 + + G + + E +P++ FTG + +K+ A E + G Sbjct: 200 GVFNVLTGSGREVGTWITE-HPRIEKVSFTGGTDTGKKVMASASSSSLKEVTMELGGKSP 258 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMH---KNWSSSGLLEKMKKLSE-RR 558 ++ D ++D + + + SGQ C+ + +F+ K + +LE++K++ Sbjct: 259 LIVFDDADLDRAADIAMMANFYSSGQVCTNGTRVFVPNALKGEFEAKILERVKRIRPGNP 318 Query: 559 KLEDLTIGPVLTVTTSTMIEHMNNLL 636 + E++ GP+++ EHM ++L Sbjct: 319 EDENINFGPLVS------FEHMESVL 338
>AL1A2_RAT (Q63639) Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2)| (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) Length = 518 Score = 48.5 bits (114), Expect = 2e-05 Identities = 42/157 (26%), Positives = 67/157 (42%), Gaps = 5/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ AL GN V+K + + M L+ E G P Sbjct: 176 PIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 V+ + G T + FTGS+ V KL + GR L+ + P++ Sbjct: 236 VNILPGYGPTAGAAIASHIGIDKIAFTGSTEVG-KLIQEAAGRSNLKRVTLELGGKSPNI 294 Query: 409 ----QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 ++DY Q + GQ C+A S +F+ ++ Sbjct: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331
>AL1A2_MOUSE (Q62148) Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2)| (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) Length = 518 Score = 48.5 bits (114), Expect = 2e-05 Identities = 42/157 (26%), Positives = 67/157 (42%), Gaps = 5/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ AL GN V+K + + M L+ E G P Sbjct: 176 PIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 V+ + G T + FTGS+ V KL + GR L+ + P++ Sbjct: 236 VNILPGYGPTAGAAIASHIGIDKIAFTGSTEVG-KLIQEAAGRSNLKRVTLELGGKSPNI 294 Query: 409 ----QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 ++DY Q + GQ C+A S +F+ ++ Sbjct: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331
>BETB_PSEU2 (Q4ZM62) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 48.5 bits (114), Expect = 2e-05 Identities = 47/206 (22%), Positives = 95/206 (46%), Gaps = 9/206 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K S+ ++ + E G+P Sbjct: 140 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGVPN 199 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGRIKLE---DAGFDWK 390 + + G + + E +P++ FTG + +K+ A E + G Sbjct: 200 GVFNVLTGSGREVGTWITE-HPRIEKVSFTGGTDTGKKVMASASSSSLKEVTMELGGKSP 258 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMH---KNWSSSGLLEKMKKL-SERR 558 ++ D ++D + + + SGQ C+ + +F+ K + +LE++K++ + Sbjct: 259 LIVFDDADLDRAADIAMMANFYSSGQVCTNGTRVFVPNALKAEFEAKILERVKRIRAGNP 318 Query: 559 KLEDLTIGPVLTVTTSTMIEHMNNLL 636 + E++ GP+++ EHM ++L Sbjct: 319 EDENINFGPLVS------FEHMESVL 338
>BETB_PSEAE (Q9HTJ1) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/176 (23%), Positives = 83/176 (47%), Gaps = 9/176 (5%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K + ++ + E G+P Sbjct: 140 REPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYTEAGVPD 199 Query: 226 EDVDFINSDGITMNKLLLEANP--KMTLFTGSSRVAEKLAADLQG----RIKLEDAGFDW 387 + + G + + L E +P + FTG + +K+ A + +E G Sbjct: 200 GVFNVLTGSGREVGQWLTE-HPLIEKISFTGGTSTGKKVMASASSSSLKEVTMELGGKSP 258 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKL 546 I+ PD ++D + + + SGQ C+ + +F+H++ + + +LE+++++ Sbjct: 259 LIIFPDA-DLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEAKVLERVQRI 313
>BETB_PSE14 (Q48CM6) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 48.5 bits (114), Expect = 2e-05 Identities = 47/206 (22%), Positives = 95/206 (46%), Gaps = 9/206 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K S+ ++ + E G+P Sbjct: 140 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGVPN 199 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGRIKLE---DAGFDWK 390 + + G + + E +P++ FTG + +K+ A E + G Sbjct: 200 GVFNVLTGSGREVGTWITE-HPRIEKVSFTGGTDTGKKVMASASSSSLKEVTMELGGKSP 258 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMH---KNWSSSGLLEKMKKL-SERR 558 ++ D ++D + + + SGQ C+ + +F+ K + +LE++K++ + Sbjct: 259 LIVFDDADLDRAADIAMMANFYSSGQVCTNGTRVFVPNALKAEFEAKILERVKRIRAGNP 318 Query: 559 KLEDLTIGPVLTVTTSTMIEHMNNLL 636 + E++ GP+++ EHM ++L Sbjct: 319 EDENINFGPLVS------FEHMESVL 338
>PUT2_AGABI (P78568) Delta-1-pyrroline-5-carboxylate dehydrogenase (EC| 1.5.1.12) (P5C dehydrogenase) Length = 546 Score = 48.5 bits (114), Expect = 2e-05 Identities = 53/192 (27%), Positives = 82/192 (42%), Gaps = 9/192 (4%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR G V ++PFNF L AL +GN V K + + ++L E G+P Sbjct: 181 YRPLEGFVLAVSPFNFTAIGGNLPGSPAL-VGNVVVWKPAPAATYSNYLVFKILSEAGVP 239 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQG---------RIKLEDA 375 + FI + + N + FTGS+ V + L D+ RI E Sbjct: 240 PGVIQFIPGGAEIVQAAIQSPNFRSLHFTGSTNVFKSLWKDISSNLDKYKVYPRIVGETG 299 Query: 376 GFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSER 555 G +W ++ EV + A+ GQKCSA S L++ ++ +G K + L E Sbjct: 300 GKNWHVIHKSA-EVRNAVLQSVRGAFEYQGQKCSALSRLYVSRSVWENGF--KTQYLEEI 356 Query: 556 RKLEDLTIGPVL 591 K++ +GP L Sbjct: 357 AKIK---VGPCL 365
>BETB_YERPE (Q8ZGV9) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 48.1 bits (113), Expect = 2e-05 Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 8/175 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+PL+I L + AL GN + K S+ ++ + E GLPA Sbjct: 140 REPLGVVAGIGAWNYPLQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAGIYTEAGLPA 199 Query: 226 EDVDFINSDGITMNKLLLE-ANPKMTLFTGSSRVAEKLAADLQGR----IKLEDAGFDWK 390 + + G + ++L E FTG +K+ A+ G + +E G Sbjct: 200 GVFNVLTGSGDQVGQMLTEHPGIAKVSFTGGIASGKKVMANAAGSTLKDVTMELGGKSPL 259 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSS---GLLEKMKKL 546 I+ D ++D + + + SGQ C+ + +F+ + ++ ++E++K++ Sbjct: 260 IIFADA-DLDKAADIAMMANFYSSGQVCTNGTRVFVPQALQAAFEQKIVERVKRI 313
>ALDH2_BOVIN (P20000) Aldehyde dehydrogenase, mitochondrial precursor (EC| 1.2.1.3) (ALDH class 2) (ALDHI) (ALDH-E2) Length = 520 Score = 48.1 bits (113), Expect = 2e-05 Identities = 46/160 (28%), Positives = 68/160 (42%), Gaps = 8/160 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + +L AL GN V+KV + + + L+ E G P Sbjct: 178 PVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGV 237 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAE--KLAADLQG--RIKLEDAGFDWKIL 396 V+ I G T + + FTGS+ V ++AA R+ LE G I+ Sbjct: 238 VNVIPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGKSNLKRVTLEIGGKSPNII 297 Query: 397 GPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKN 507 D + W +Q +A GQ C A S F+ ++ Sbjct: 298 MSDAD----MDWAVEQAHFALFFNQGQCCCAGSRTFVQED 333
>AL1A2_HUMAN (O94788) Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2)| (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) Length = 518 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 5/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ AL GN V+K + + M L+ E G P Sbjct: 176 PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 ++ + G T + FTGS+ V KL + GR L+ + P++ Sbjct: 236 INILPGYGPTAGAAIASHIGIDKIAFTGSTEVG-KLIQEAAGRSNLKRVTLELGGKSPNI 294 Query: 409 ----QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 ++DY Q + GQ C+A S +F+ ++ Sbjct: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEES 331
>PUT2_YEAST (P07275) Delta-1-pyrroline-5-carboxylate dehydrogenase,| mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) Length = 575 Score = 47.8 bits (112), Expect = 3e-05 Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 13/174 (7%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGA-LYMGNKPVLKVDSKVSIVMEQMIRLLHECGL 219 YR G V ++PFNF L+GA MGN V K ++ ++ +L E GL Sbjct: 198 YRPLEGFVYAVSPFNFTAIAA--NLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGL 255 Query: 220 PAEDVDFINSDGITM-NKLLLEANPKMTLFTGSSRVAEKLAADLQG-----------RIK 363 P ++FI D + + +++L + + FTGS+ V + L +Q RI Sbjct: 256 PKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRII 315 Query: 364 LEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGL 525 E G ++ ++ P + + + + GQKCSA S L++ ++ S L Sbjct: 316 GETGGKNFHLVHPSA-NISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFL 368
>ALDH2_MESAU (P81178) Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH| class 2) (ALDH1) (ALDH-E2) Length = 500 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/160 (28%), Positives = 68/160 (42%), Gaps = 8/160 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + +L AL GN V+KV + + + L+ E G P Sbjct: 158 PVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGV 217 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAE--KLAADLQG--RIKLEDAGFDWKIL 396 V+ + G T + + FTGS+ V ++AA R+ LE G I+ Sbjct: 218 VNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNII 277 Query: 397 GPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKN 507 D + W +Q +A GQ C A S F+ ++ Sbjct: 278 MSDAD----MDWAVEQAHFALFFNQGQCCCAGSRTFVQED 313
>BETB_YERPS (Q66D53) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 47.8 bits (112), Expect = 3e-05 Identities = 41/156 (26%), Positives = 70/156 (44%), Gaps = 5/156 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+PL+I L + AL GN + K S+ ++ + E GLPA Sbjct: 140 REPLGVVAGIGAWNYPLQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAGIYTEAGLPA 199 Query: 226 EDVDFINSDGITMNKLLLE-ANPKMTLFTGSSRVAEKLAADLQGR----IKLEDAGFDWK 390 + + G + ++L E FTG +K+ A+ G + +E G Sbjct: 200 GVFNVLTGSGDQVGQMLTEHPGIAKVSFTGGIASGKKVMANAAGSTLKDVTMELGGKSPL 259 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM 498 I+ D ++D + + + SGQ C+ + +F+ Sbjct: 260 IIFADA-DLDKAADIAMMANFYSSGQVCTNGTRVFV 294
>ALDH2_RAT (P11884) Aldehyde dehydrogenase, mitochondrial precursor (EC| 1.2.1.3) (ALDH class 2) (ALDH1) (ALDH-E2) Length = 519 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/160 (28%), Positives = 68/160 (42%), Gaps = 8/160 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + +L AL GN V+KV + + + L+ E G P Sbjct: 177 PVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGV 236 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAE--KLAADLQG--RIKLEDAGFDWKIL 396 V+ + G T + + FTGS+ V ++AA R+ LE G I+ Sbjct: 237 VNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNII 296 Query: 397 GPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKN 507 D + W +Q +A GQ C A S F+ ++ Sbjct: 297 MSDAD----MDWAVEQAHFALFFNQGQCCCAGSRTFVQED 332
>ALDH2_HUMAN (P05091) Aldehyde dehydrogenase, mitochondrial precursor (EC| 1.2.1.3) (ALDH class 2) (ALDHI) (ALDH-E2) Length = 517 Score = 47.4 bits (111), Expect = 4e-05 Identities = 44/160 (27%), Positives = 68/160 (42%), Gaps = 8/160 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + +L AL GN V+KV + + + L+ E G P Sbjct: 175 PVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGV 234 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAE--KLAADLQG--RIKLEDAGFDWKIL 396 V+ + G T + + FTGS+ + ++AA R+ LE G I+ Sbjct: 235 VNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNII 294 Query: 397 GPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKN 507 D + W +Q +A GQ C A S F+ ++ Sbjct: 295 MSDAD----MDWAVEQAHFALFFNQGQCCCAGSRTFVQED 330
>ALDH_AGABI (O74187) Aldehyde dehydrogenase (EC 1.2.1.3) (ALDDH)| Length = 500 Score = 47.4 bits (111), Expect = 4e-05 Identities = 47/184 (25%), Positives = 84/184 (45%), Gaps = 7/184 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFPL + ++ AL GN VLK + +M L+ E G P Sbjct: 159 PIGVVGQIIPWNFPLLMLAWKIGPALATGNCIVLKPSEFTPLSALRMCALIQEAGFPPGV 218 Query: 232 VDFINSDGITMNKLLLEANPKM--TLFTGSS----RVAEKLAADLQGRIKLEDAGFDWKI 393 V+ + G T + + ++ K+ FTGS+ +V E A + LE G + Sbjct: 219 VNVVTGYGSTTGQ-AISSHMKIDKVAFTGSTLVGRKVMEAAAKSNLKNVTLELGGKSPVV 277 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK-MKKLSERRKLED 570 + D ++W + GQ C A + +F+ + G+ +K ++K ++ K+++ Sbjct: 278 IFDDADLEQSVNWTA-HGLFWNHGQACCAGTRIFVQE-----GIYDKFLQKFTD--KIKE 329 Query: 571 LTIG 582 + +G Sbjct: 330 IKLG 333
>BETB_ACIAD (Q6FDF8) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 47.4 bits (111), Expect = 4e-05 Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 8/175 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K + ++ + E GLPA Sbjct: 140 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTAFKLAEIYSEAGLPA 199 Query: 226 EDVDFINSDGITMNKLLLE-ANPKMTLFTGSSRVAEKLAADLQG----RIKLEDAGFDWK 390 + + G + + L E A + FTG +K+ A G + +E G Sbjct: 200 GVFNVVQGAGREIGQWLTEHAVIEKISFTGGVETGKKVMASAAGSTLKEVTMELGGKSPL 259 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSS---GLLEKMKKL 546 I+ D +D + + + SGQ C+ + +F+ + ++ ++E++K++ Sbjct: 260 IICEDA-NLDRAADIAVMANFFSSGQVCTNGTRVFIPQRLKAAFEQAVVERVKRI 313
>AL1A1_SHEEP (P51977) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 500 Score = 47.0 bits (110), Expect = 5e-05 Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 6/158 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + L ++ AL GN V+K + + M L+ E G P Sbjct: 158 PVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGV 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G T + + FTGS+ V KL + G R+ LE G I Sbjct: 218 VNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVG-KLIKEAAGKSNLKRVSLELGGKSPCI 276 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + D ++D Q + GQ C A S LF+ ++ Sbjct: 277 VFADA-DLDNAVEFAHQGVFYHQGQCCIAASRLFVEES 313
>AL1A1_BOVIN (P48644) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 500 Score = 47.0 bits (110), Expect = 5e-05 Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 6/158 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + L ++ AL GN V+K + + M L+ E G P Sbjct: 158 PVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGV 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G T + + FTGS+ V KL + G R+ LE G I Sbjct: 218 VNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVG-KLIKEAAGKSNLKRVSLELGGKSPCI 276 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + D ++D Q + GQ C A S LF+ ++ Sbjct: 277 VFADA-DLDNAVEFAHQGVFYHQGQCCIAASRLFVEES 313
>AL4A1_MOUSE (Q8CHT0) Delta-1-pyrroline-5-carboxylate dehydrogenase,| mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1) Length = 562 Score = 47.0 bits (110), Expect = 5e-05 Identities = 54/189 (28%), Positives = 83/189 (43%), Gaps = 13/189 (6%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR G VA I+PFNF L AL MGN + K + + R+L E GLP Sbjct: 196 YRGLEGFVAAISPFNFTAIGGNLAGAPAL-MGNVVLWKPSDTAMLASYAVYRILREAGLP 254 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTL-FTGS----SRVAEKLAADLQ-----GRIKLED 372 + F+ +DG T + + + FTGS + ++A +L R+ E Sbjct: 255 PNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGEC 314 Query: 373 AGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN-WS--SSGLLEKMKK 543 G ++ + +VD + + A+ GQKCSA S L++ K+ W LLE+ + Sbjct: 315 GGKNFHFVHSSA-DVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSR 373 Query: 544 LSERRKLED 570 + ED Sbjct: 374 IKVGDPAED 382
>AL1A2_POEGU (Q9I8W8) Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2)| (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) (zRalDH) Length = 517 Score = 47.0 bits (110), Expect = 5e-05 Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 5/173 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ AL GN V+K + + M L+ E G P Sbjct: 176 PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 Query: 232 VDFINSDG-ITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 V+ + G I + FTGS+ V KL + GR L+ + P++ Sbjct: 236 VNILPGFGPIVGAAIASHVGIDKIAFTGSTEVG-KLIQEAAGRSNLKRVTLELGGKSPNI 294 Query: 409 ----QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSER 555 ++DY Q + GQ C+A S +++ ++ + + +K+ + Sbjct: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIYVEESIYEEFVRKSVKRAKRK 347
>AL1A2_CHICK (O93344) Retinal dehydrogenase 2 (EC 1.2.1.36) (RalDH2) (RALDH 2)| (RALDH(II)) (Retinaldehyde-specific dehydrogenase type 2) (Aldehyde dehydrogenase family 1 member A2) Length = 518 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 5/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ AL GN V+K + + M L+ E G P Sbjct: 176 PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGV 235 Query: 232 VDFINSDG-ITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 V+ + G I + FTGS+ V KL + GR L+ + P++ Sbjct: 236 VNILPGFGPIVGAAIASHVGIDKIAFTGSTEVG-KLIQEAAGRSNLKRVTLELGGKSPNI 294 Query: 409 ----QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 ++DY Q + GQ C+A S +++ ++ Sbjct: 295 IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIYVEES 331
>ALDH2_HORSE (P12762) Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH| class 2) (ALDHI) (ALDH-E2) Length = 500 Score = 46.6 bits (109), Expect = 6e-05 Identities = 43/157 (27%), Positives = 65/157 (41%), Gaps = 5/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + +L AL GN V+KV + + + L E G P Sbjct: 158 PVGVCGQIIPWNFPLLMQAAKLGPALATGNVVVMKVAEQTPLTALYVANLTKEAGFPPGV 217 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 V+ + G T + + FTGS+ V L GR L+ + P++ Sbjct: 218 VNVVPGFGPTAGAAIASHEDVDKVAFTGSTEVGH-LIQVAAGRSNLKKVTLELGGKSPNI 276 Query: 409 QEVDY-ISWVCDQDAYAC---SGQKCSAQSMLFMHKN 507 D + W +Q +A GQ C A S F+ ++ Sbjct: 277 IVSDADMDWAVEQAHFALFFNQGQCCGAGSRTFVQED 313
>PUT2_SCHPO (O74766) Probable delta-1-pyrroline-5-carboxylate dehydrogenase (EC| 1.5.1.12) (P5C dehydrogenase) Length = 548 Score = 46.6 bits (109), Expect = 6e-05 Identities = 55/202 (27%), Positives = 85/202 (42%), Gaps = 19/202 (9%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR G V ITPFNF L L MGN ++K + + ++ E GLP Sbjct: 179 YRPLEGFVYAITPFNFTAIAGNLAA-APLLMGNVVLMKPSDHAVLSSYIVYQIFREAGLP 237 Query: 223 AEDVDFINSDGITMNKLLLEANPKMT--LFTGSSRVAEKLAADL-----------QGRIK 363 A + FI D + ++K+ +P+ FTGS+ V L + +I Sbjct: 238 AGALQFIPGDAVEVSKVCFN-HPEFAGLHFTGSTAVFRSLWGTIGENVANGKYRTYPKIV 296 Query: 364 LEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK----NWSSSGLLE 531 E G ++ ++ E+ + A+ GQKCSA S L++ K N L + Sbjct: 297 GETGGKNFHLVHSSA-EIKSAVVNAVRAAFEYQGQKCSALSRLYVSKYAWENGFRDELTK 355 Query: 532 KMKKLSERRKLEDLT--IGPVL 591 ++K L L D +GPV+ Sbjct: 356 QVKSLKVGAPLTDFANFVGPVI 377
>BETB_XANCP (Q8P5D8) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 46.6 bits (109), Expect = 6e-05 Identities = 45/202 (22%), Positives = 92/202 (45%), Gaps = 11/202 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I +N+P++I L + AL GN + K + ++ + E GLP Sbjct: 142 PLGVVGAIGAWNYPIQIALWKAAPALAAGNAMIFKPSEVTPLTALKLAEIFTEAGLPDGV 201 Query: 232 VDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGR----IKLEDAGFDWKI 393 + + DG ++ L E +P++ FTG + K+ A + +E G I Sbjct: 202 FNVLPGDGASVGHALTE-HPEIEKISFTGGTATGRKVMASASSSSLKDVTMELGGKSPLI 260 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSERRKL 564 + D ++D + + + SGQ C+ + +F+ + + + LL +++++ L Sbjct: 261 VCADA-DLDLAADIAMMANFYSSGQVCTNGTRVFVPRALRTAFEARLLARVQRIHIGDPL 319 Query: 565 ED-LTIGPVLTVT-TSTMIEHM 624 ++ T GP+++ ++EH+ Sbjct: 320 DERTTFGPMVSAAHMQRVLEHI 341
>BETB_XANC8 (Q4UYN4) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 46.6 bits (109), Expect = 6e-05 Identities = 45/202 (22%), Positives = 92/202 (45%), Gaps = 11/202 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I +N+P++I L + AL GN + K + ++ + E GLP Sbjct: 142 PLGVVGAIGAWNYPIQIALWKAAPALAAGNAMIFKPSEVTPLTALKLAEIFTEAGLPDGV 201 Query: 232 VDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGR----IKLEDAGFDWKI 393 + + DG ++ L E +P++ FTG + K+ A + +E G I Sbjct: 202 FNVLPGDGASVGHALTE-HPEIEKISFTGGTATGRKVMASASSSSLKDVTMELGGKSPLI 260 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSERRKL 564 + D ++D + + + SGQ C+ + +F+ + + + LL +++++ L Sbjct: 261 VCADA-DLDLAADIAMMANFYSSGQVCTNGTRVFVPRALRTAFEARLLARVQRIHIGDPL 319 Query: 565 ED-LTIGPVLTVT-TSTMIEHM 624 ++ T GP+++ ++EH+ Sbjct: 320 DERTTFGPMVSAAHMQRVLEHI 341
>AL1A1_RAT (P51647) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 500 Score = 46.2 bits (108), Expect = 8e-05 Identities = 44/160 (27%), Positives = 69/160 (43%), Gaps = 6/160 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G I P+NFPL + + ++ AL GN V+K + + M L+ E G P Sbjct: 156 REPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTALHMASLIKEAGFPP 215 Query: 226 EDVDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDW 387 V+ + G T + + FTGS++V KL + G R+ LE G Sbjct: 216 GVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVG-KLIKEAAGKSNLKRVTLELGGKSP 274 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 I+ D ++D + GQ C A S +F+ ++ Sbjct: 275 CIVFADA-DLDIAVEFAHHGVFYHQGQCCVAASRIFVEES 313
>BETB_XANAC (Q8PPG7) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 46.2 bits (108), Expect = 8e-05 Identities = 45/202 (22%), Positives = 91/202 (45%), Gaps = 11/202 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I +N+P++I L + AL GN + K + ++ + E GLP Sbjct: 142 PLGVVGAIGAWNYPIQIALWKAAPALAAGNAMIFKPSEVTPLTALKLAEIFTEAGLPDGV 201 Query: 232 VDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQG----RIKLEDAGFDWKI 393 + + DG ++ L E +P++ FTG + K+ A + +E G I Sbjct: 202 FNVLPGDGASVGTALTE-HPQIEKISFTGGTATGRKVMASASSSSLKEVTMELGGKSPLI 260 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMH---KNWSSSGLLEKMKKLSERRKL 564 + D ++D + + + SGQ C+ + +F+ ++ + LL +++++ L Sbjct: 261 VCADA-DLDVAADIAMMANFYSSGQVCTNGTRVFVPRALRHAFEARLLARVQRIHIGDPL 319 Query: 565 ED-LTIGPVLTVT-TSTMIEHM 624 ++ T GP+ + ++EH+ Sbjct: 320 DERTTFGPLASAAHMQRVLEHI 341
>ALDH4_YEAST (P46367) Potassium-activated aldehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.3) (K(+)-activated acetaldehyde dehydrogenase) (K(+)-ACDH) Length = 519 Score = 45.8 bits (107), Expect = 1e-04 Identities = 45/181 (24%), Positives = 83/181 (45%), Gaps = 6/181 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G I P+NFPL + ++ AL GN VLK + + + + + G+P Sbjct: 179 RQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPP 238 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSS----RVAEKLAADLQGRIKLEDAGFDW 387 ++ ++ G + + + +PK+ FTGS+ + + AA L+ ++ LE G Sbjct: 239 GVINIVSGFGKIVGEAITN-HPKIKKVAFTGSTATGRHIYQSAAAGLK-KVTLELGGKSP 296 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLE 567 I+ D + + + Y SG+ C A S +++ ++ +E+ K SE K+ Sbjct: 297 NIVFADAELKKAVQNII-LGIYYNSGEVCCAGSRVYVEESIYDK-FIEEFKAASESIKVG 354 Query: 568 D 570 D Sbjct: 355 D 355
>ALDH1_ENTHI (P30840) Aldehyde dehydrogenase 1 (EC 1.2.1.3)| Length = 529 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/98 (32%), Positives = 54/98 (55%), Gaps = 3/98 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P+G V +I+P+NFP + L+ GAL GN LK+ SK S+ ++I L + +P+ Sbjct: 164 REPYGCVCVISPWNFPANLSLIPCAGALACGNTVFLKM-SKYSMATSKLIAELCDKYIPS 222 Query: 226 EDVDFINSDGITMNKLLLE---ANPKMTLFTGSSRVAE 330 E ++ + +T + + E A+ FTGS+ V + Sbjct: 223 E---YLRCEYLTGREAIQECCSASFDYYFFTGSTYVGK 257
>AL7A1_DICDI (P83401) Putative aldehyde dehydrogenase family 7 member A1 homolog| (EC 1.2.1.3) (Antiquitin-1) Length = 509 Score = 45.4 bits (106), Expect = 1e-04 Identities = 44/195 (22%), Positives = 90/195 (46%), Gaps = 14/195 (7%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V IIT FNFP + ++ GN + K S S++ + +++ + L D Sbjct: 153 PLGLVGIITAFNFPCAVLGWNAAISMICGNVQLWKGASTTSLITLAVSKIIEKV-LVEND 211 Query: 232 VD------FINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQ---GRIKLEDAGFD 384 VD I +++ + + FTGS+ V ++++ + G+ LE G + Sbjct: 212 VDPAVCCVLIGPGRTVGEQMIQDKRFGLISFTGSTEVGRRISSTVHGYFGKTILELGGNN 271 Query: 385 WKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL 564 ++ D +++ + + +GQ+C+ LF+H++ + +LE++ K + K+ Sbjct: 272 AIVVAEDA-DIELVLRAVLFASVGTTGQRCTTCRRLFVHESLYDT-ILERLTKAYKTIKI 329 Query: 565 -----EDLTIGPVLT 594 E + +GP+ T Sbjct: 330 GNPLEEGVLVGPLHT 344
>AL1A1_RABIT (Q8MI17) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 496 Score = 45.4 bits (106), Expect = 1e-04 Identities = 43/158 (27%), Positives = 68/158 (43%), Gaps = 6/158 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + + ++ AL GN ++K + + + L+ E G P Sbjct: 154 PVGVCGQIIPWNFPLVMLIWKIGPALSCGNTVIVKPAEQTPLTALHVASLIKEAGFPPGV 213 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G T + + FTGS+ V KL + G R+ LE G I Sbjct: 214 VNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVG-KLIKEAAGKSNLKRVTLELGGKSPCI 272 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + D ++D Q + GQ C A S LF+ ++ Sbjct: 273 VFADA-DLDNAVEFAHQGVFYHQGQCCIAASRLFVEES 309
>AL4A1_HUMAN (P30038) Delta-1-pyrroline-5-carboxylate dehydrogenase,| mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1) Length = 563 Score = 45.4 bits (106), Expect = 1e-04 Identities = 56/197 (28%), Positives = 84/197 (42%), Gaps = 18/197 (9%) Frame = +1 Query: 34 SNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHEC 213 S YR G VA I+PFNF L AL MGN + K + + R+L E Sbjct: 194 STVYRGLEGFVAAISPFNFTAIGGNLAGAPAL-MGNVVLWKPSDTAMLASYAVYRILREA 252 Query: 214 GLPAEDVDFINSDG------ITMNKLLLEANPKMTLFTGS----SRVAEKLAADLQ---- 351 GLP + F+ +DG +T ++ L N FTGS + +++A +L Sbjct: 253 GLPPNIIQFVPADGPLFGDTVTSSEHLCGIN-----FTGSVPTFKHLWKQVAQNLDRFHT 307 Query: 352 -GRIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM-HKNWS--SS 519 R+ E G ++ + +S + A+ GQKCSA S L++ H W Sbjct: 308 FPRLAGECGGKNFHFVHRSADVESVVSGTL-RSAFEYGGQKCSACSRLYVPHSLWPQIKG 366 Query: 520 GLLEKMKKLSERRKLED 570 LLE+ ++ ED Sbjct: 367 RLLEEHSRIKVGDPAED 383
>ALDHY_YEAST (P32872) Aldehyde dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.3) Length = 511 Score = 45.1 bits (105), Expect = 2e-04 Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 9/173 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+N PL + + ++ AL GN VLK + + + L+ E G P Sbjct: 187 PVGVCGEIIPWNIPLLMYIWKIGPALAAGNTVVLKPEELTPLTALTVATLIKEAGFPPGV 246 Query: 232 VDFINSDGITMNKLLL--EANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPD 405 V+ ++ G T L + N K+ FTGS+ V K+ + L+ + P Sbjct: 247 VNVVSGYGPTAGAACLSHKDNDKLA-FTGSTLVG-KVVMKAAAKSNLKKVTLELGGKSPM 304 Query: 406 VQEVDY-ISWVCDQDAYAC---SGQKCSAQSMLFMHKNWSSSGL---LEKMKK 543 + +D + W + + GQ C AQS + +H++ + LEK KK Sbjct: 305 IVFIDADLDWAVENAHFGVFFNQGQCCIAQSRITVHESIYDEIVERDLEKAKK 357
>AL1A1_HORSE (P15437) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 500 Score = 45.1 bits (105), Expect = 2e-04 Identities = 45/158 (28%), Positives = 69/158 (43%), Gaps = 6/158 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + L ++ AL GN V+K + + + L+ E G P Sbjct: 158 PVGVCGQILPWNFPLLMFLWKIAPALSCGNTVVVKPAEQTPLSALHVATLIKEAGFPPGV 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G T + + FTGS+ V KL + G R+ LE G I Sbjct: 218 VNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVG-KLIKEAAGKSNLKRVTLELGGKSPFI 276 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + D +++ V Q + GQ C A S LF+ ++ Sbjct: 277 VFADA-DLETALEVTHQALFYHQGQCCVAASRLFVEES 313
>GABD_RHISN (P55653) Probable succinate-semialdehyde dehydrogenase [NADP+] (EC| 1.2.1.16) (SSDH) Length = 491 Score = 44.7 bits (104), Expect = 2e-04 Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 13/202 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V ITP+NFP + ++ AL G VLK + +V M L G P Sbjct: 153 PIGVVGAITPWNFPASMVARKISPALAAGCTVVLKPAEQTPLVAGAMFALAKLAGFPDGV 212 Query: 232 VDFI-NSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGRIK--LEDAGFDWKIL 396 ++ + S+G + + L NPK+ FTGS+ V L +IK + G + + Sbjct: 213 LNLVYASEGDAIGRELC-TNPKVRKISFTGSTEVGRLLMRQCSDQIKRISFELGGNAPFI 271 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSER-RKLE-- 567 D ++D Q + +GQ C + + +++ S E +K +ER R L+ Sbjct: 272 VFDDADIDAAVDGAIQAKFRNAGQTCVSANRIYV----QSGVYAEFAEKFTERVRTLKVG 327 Query: 568 -----DLTIGPVLTVTTSTMIE 618 ++ IGP++ IE Sbjct: 328 DGFDPNVAIGPLINQEALKKIE 349
>NAHF_PSEU8 (P0A390) Salicylaldehyde dehydrogenase (EC 1.2.1.65)| Length = 483 Score = 44.3 bits (103), Expect = 3e-04 Identities = 52/219 (23%), Positives = 89/219 (40%), Gaps = 16/219 (7%) Frame = +1 Query: 31 MSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHE 210 +S R P GP+ I P+N + + L GN V K + + + E Sbjct: 131 LSMTLRQPVGPILSIVPWNGTAVLAARAIAYPLVCGNTVVFKGSEFSPATHALITQCVQE 190 Query: 211 CGLPAEDVDFINS---------DGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK 363 GLPA ++++NS D + K + N FTGS+RV +A +K Sbjct: 191 AGLPAGVLNYLNSSPDRSPEIADALISAKEIRRIN-----FTGSTRVGSIIAQKAAQHLK 245 Query: 364 --LEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLL 528 L + G ++ D ++D ++ GQ C + L + + + + + Sbjct: 246 RCLLELGGKSPLIVLDDADIDAAVKAAVFGSFLFQGQICMSTERLIVDEKIADEFVAKFV 305 Query: 529 EKMKKLS--ERRKLEDLTIGPVLTVTTSTMIEHMNNLLK 639 EK K+LS + D IGP+++ + E +N L K Sbjct: 306 EKTKRLSAGDPCVTGDCIIGPMVSPNSG---ERINGLFK 341
>NAHF_PSEPU (P0A391) Salicylaldehyde dehydrogenase (EC 1.2.1.65)| Length = 483 Score = 44.3 bits (103), Expect = 3e-04 Identities = 52/219 (23%), Positives = 89/219 (40%), Gaps = 16/219 (7%) Frame = +1 Query: 31 MSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHE 210 +S R P GP+ I P+N + + L GN V K + + + E Sbjct: 131 LSMTLRQPVGPILSIVPWNGTAVLAARAIAYPLVCGNTVVFKGSEFSPATHALITQCVQE 190 Query: 211 CGLPAEDVDFINS---------DGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK 363 GLPA ++++NS D + K + N FTGS+RV +A +K Sbjct: 191 AGLPAGVLNYLNSSPDRSPEIADALISAKEIRRIN-----FTGSTRVGSIIAQKAAQHLK 245 Query: 364 --LEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLL 528 L + G ++ D ++D ++ GQ C + L + + + + + Sbjct: 246 RCLLELGGKSPLIVLDDADIDAAVKAAVFGSFLFQGQICMSTERLIVDEKIADEFVAKFV 305 Query: 529 EKMKKLS--ERRKLEDLTIGPVLTVTTSTMIEHMNNLLK 639 EK K+LS + D IGP+++ + E +N L K Sbjct: 306 EKTKRLSAGDPCVTGDCIIGPMVSPNSG---ERINGLFK 341
>ALDH6_YEAST (P54115) Magnesium-activated aldehyde dehydrogenase, cytosolic (EC| 1.2.1.3) (Mg(2+)-activated acetaldehyde dehydrogenase) (Mg(2+)-ACDH) Length = 499 Score = 44.3 bits (103), Expect = 3e-04 Identities = 39/156 (25%), Positives = 70/156 (44%), Gaps = 5/156 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFP+ + ++ AL MGN +LK + + L + G+PA Sbjct: 161 PIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGV 220 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQ----GRIKLEDAGFDWKIL 396 V+ + G T+ L + + FTGS+ V + +A D +I LE G ++ Sbjct: 221 VNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLV 280 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 D + + + + +GQ CS+ S +++ + Sbjct: 281 FDDANIKKTLPNLVN-GIFKNAGQICSSGSRIYVQE 315
>AL1A4_RAT (P13601) Aldehyde dehydrogenase, cytosolic 1 (EC 1.2.1.3) (ALDH| class 1) (ALHDII) (ALDH-E1) (Aldehyde dehydrogenase family 1 member A4) Length = 500 Score = 44.3 bits (103), Expect = 3e-04 Identities = 44/160 (27%), Positives = 68/160 (42%), Gaps = 6/160 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G I P+N PL + + ++ AL GN ++K + + M L+ E G P Sbjct: 156 REPIGVCGQIIPWNGPLILFIWKIGAALSCGNTVIVKPAEQTPLTALYMASLIKEAGFPP 215 Query: 226 EDVDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDW 387 V+ + G T + + FTGS+ V KL + G R+ LE G Sbjct: 216 GVVNVVPGYGSTAGAAISSHMDIDKVSFTGSTEVG-KLIKEAAGKSNLKRVTLELGGKSP 274 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 I+ D ++D Q + GQ C A S LF+ ++ Sbjct: 275 CIVFADA-DLDSAVEFAHQGVFFHQGQICVAASRLFVEES 313
>AL1A1_MOUSE (P24549) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 500 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 6/160 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G I P+NFP+ + + ++ AL GN V+K + + + L+ E G P Sbjct: 156 REPIGVCGQIIPWNFPMLMFIWKIGPALSCGNTVVVKPAEQTPLTALHLASLIKEAGFPP 215 Query: 226 EDVDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDW 387 V+ + G T + + FTGS++V KL + G R+ LE G Sbjct: 216 GVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTQVG-KLIKEAAGKSNLKRVTLELGGKSP 274 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 I+ D ++D + GQ C A S +F+ ++ Sbjct: 275 CIVFADA-DLDIAVEFAHHGVFYHQGQCCVAASRIFVEES 313
>AL7A1_CAEEL (P46562) Putative aldehyde dehydrogenase family 7 member A1 homolog| (EC 1.2.1.3) (ALH-9) Length = 531 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/172 (25%), Positives = 76/172 (44%), Gaps = 8/172 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +I+ FNFP + AL GN V K + + +L+ E L A + Sbjct: 174 PLGVVGVISAFNFPCAVYGWNNALALVTGNSVVWKPAPSTPLTAIAVTKLVEEV-LVANN 232 Query: 232 VD-----FINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQ---GRIKLEDAGFDW 387 V+ + +G L+ + + FTGSS + + + +Q G++ LE G + Sbjct: 233 VNPALCSLVCGEGDVGQALVKDKRVNLVSFTGSSEIGKIVGQQVQARFGKLLLELGGNNA 292 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKK 543 I+ D +++ + A +GQ+C+ L +H +LE++KK Sbjct: 293 IIVNEDA-DLNMVVPATVFAAVGTAGQRCTTTRRLIVHDKVYDQ-VLERLKK 342
>BETB_ERWCT (Q6D6E0) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 43.9 bits (102), Expect = 4e-04 Identities = 39/158 (24%), Positives = 69/158 (43%), Gaps = 5/158 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K S+ ++ + E GLPA Sbjct: 140 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAEIYTEAGLPA 199 Query: 226 EDVDFINSDGITMNK-LLLEANPKMTLFTGSSRVAEKLAADLQGR----IKLEDAGFDWK 390 + + G ++ + L FTG + + A+ G + +E G Sbjct: 200 GVFNVLTGTGKSVGQALTTHPGIAKVSFTGGIASGKTVMANAAGSTLKDVTMELGGKSPL 259 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 I+ D ++D + + + SGQ C+ + +F+ K Sbjct: 260 IIFDDA-DLDKAADIAMMANFFSSGQVCTNGTRVFVPK 296
>XYLG_PSEPU (P23105) 2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.-)| (HMSD) Length = 486 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/165 (22%), Positives = 73/165 (44%), Gaps = 5/165 (3%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G ++ G R P G + +I+P+N PL + ++ AL GN V+K + + + ++ Sbjct: 135 GALNYGVRRPKGVIGVISPWNLPLLLMTWKVGPALACGNCVVVKPSEETPLTATLLGEVM 194 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEANPKMTLF-----TGSSRVAEKLAADLQGRIKLE 369 G+PA + ++ G L +P + + TG+ + AA ++ LE Sbjct: 195 QAAGVPAGVYNVVHGFGGDSAGAFLTEHPDVDAYTFTGETGTGETIMRAAAKGVRQVSLE 254 Query: 370 DAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 G + I+ D ++D + A+A GQ C +++ + Sbjct: 255 LGGKNAGIVFADC-DMDKAIEGTLRSAFANCGQVCLGTERVYVER 298
>BETB_VIBVY (Q7MF13) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 486 Score = 43.5 bits (101), Expect = 5e-04 Identities = 38/173 (21%), Positives = 74/173 (42%), Gaps = 3/173 (1%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G A I +N+P++I + + AL GN + K + + ++ L + G+P Sbjct: 137 REPLGICAGIGAWNYPIQIAMWKAAPALAAGNAMIFKPSEETPLSALKLAELFTQAGVPD 196 Query: 226 EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKIL 396 + + D L FTG S +K+ AD +K +E G I+ Sbjct: 197 GVFNVVQGDYRVGQMLTAHPEIAKVSFTGESGTGKKVMADSAATLKPVTMELGGKSPLII 256 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSER 555 D D +S + Y G+ C+ + +++ + + +E++K+ +E+ Sbjct: 257 FDDADLDDAVSAAMVANFYT-QGEVCTHGTRVYVQRAMYDA-FVEQLKERTEK 307
>BETB_VIBVU (Q8D3K3) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 486 Score = 43.5 bits (101), Expect = 5e-04 Identities = 38/173 (21%), Positives = 74/173 (42%), Gaps = 3/173 (1%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G A I +N+P++I + + AL GN + K + + ++ L + G+P Sbjct: 137 REPLGICAGIGAWNYPIQIAMWKAAPALAAGNAMIFKPSEETPLSALKLAELFTQAGVPD 196 Query: 226 EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKIL 396 + + D L FTG S +K+ AD +K +E G I+ Sbjct: 197 GVFNVVQGDYRVGQMLTAHPEIDKVSFTGESGTGKKVMADSAATLKPVTMELGGKSPLII 256 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSER 555 D D +S + Y G+ C+ + +++ + + +E++K+ +E+ Sbjct: 257 FDDADLDDAVSAAMVANFYT-QGEVCTHGTRVYVQRAMYDA-FVEQLKERTEK 307
>AL1A1_MACFA (Q8HYE4) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 500 Score = 43.1 bits (100), Expect = 7e-04 Identities = 42/158 (26%), Positives = 67/158 (42%), Gaps = 6/158 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + + ++ AL GN V+K + + + L+ E G P Sbjct: 158 PIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGV 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G T + + FTGS+ V KL + G R+ LE G I Sbjct: 218 VNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVG-KLIKEAAGKSNLKRVTLELGGKSPCI 276 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + D ++D + GQ C A S +F+ ++ Sbjct: 277 VLADA-DLDNAVEFAHHGVFYHQGQCCIAASRIFVEES 313
>AL1A1_HUMAN (P00352) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 500 Score = 43.1 bits (100), Expect = 7e-04 Identities = 42/158 (26%), Positives = 67/158 (42%), Gaps = 6/158 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + + ++ AL GN V+K + + + L+ E G P Sbjct: 158 PIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGV 217 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G T + + FTGS+ V KL + G R+ LE G I Sbjct: 218 VNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVG-KLIKEAAGKSNLKRVTLELGGKSPCI 276 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + D ++D + GQ C A S +F+ ++ Sbjct: 277 VLADA-DLDNAVEFAHHGVFYHQGQCCIAASRIFVEES 313
>BETB_VIBPA (Q87H52) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 486 Score = 43.1 bits (100), Expect = 7e-04 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 3/157 (1%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G A I +N+P++I + + AL GN + K + + ++ + E GLP Sbjct: 137 REPLGICAGIGAWNYPIQIAMWKSAPALAAGNAMIFKPSEETPLTALKLAEIYSEAGLPD 196 Query: 226 EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKIL 396 + + D L + FTG S + + D +K +E G I+ Sbjct: 197 GVFNVVQGDYRVGQMLTAHPDIAKVSFTGESGTGKVVMGDSAKTLKQVTMELGGKSPLIV 256 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 D + D +S + Y G+ C+ + +F+H++ Sbjct: 257 FDDAKLDDAVSAAMVANFYT-QGEVCTNGTRVFVHES 292
>AL3B1_HUMAN (P43353) Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde| dehydrogenase 7) Length = 468 Score = 43.1 bits (100), Expect = 7e-04 Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA-- 225 PFG V II P+N+PL + L+ L+GAL GN VLK S++S +E+++ + LP Sbjct: 104 PFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLK-PSEISKNVEKILAEV----LPQYV 158 Query: 226 -EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAE 330 + + G LLE FTGS RV + Sbjct: 159 DQSCFAVVLGGPQETGQLLEHRFDYIFFTGSPRVGK 194
>AL3B2_HUMAN (P48448) Aldehyde dehydrogenase 3B2 (EC 1.2.1.5) (Aldehyde| dehydrogenase 8) Length = 385 Score = 42.7 bits (99), Expect = 0.001 Identities = 34/96 (35%), Positives = 50/96 (52%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 ++ PFG V II P+N+PL + L+ L+GAL GN VLK S++S E+++ + L Sbjct: 20 WKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGNCVVLK-PSEISQGTEKVLAEVLPQYLD 78 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAE 330 + + G LLE FTGS RV + Sbjct: 79 -QSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGK 113
>AL4A1_BRARE (Q7SY23) Delta-1-pyrroline-5-carboxylate dehydrogenase,| mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) (Aldehyde dehydrogenase 4A1) Length = 556 Score = 42.7 bits (99), Expect = 0.001 Identities = 52/196 (26%), Positives = 85/196 (43%), Gaps = 18/196 (9%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR G VA + PFNF L AL MGN + K + ++L E GLP Sbjct: 190 YRGLEGFVAAVAPFNFTAIGGNLAGTPAL-MGNVVLWKPSDTAMSASYAVYKILRESGLP 248 Query: 223 AEDVDFINSDG------ITMNKLLLEANPKMTLFTGS----SRVAEKLAADLQ-----GR 357 + F+ +DG +T ++ L N FTGS R+ +++A +L R Sbjct: 249 PNIIQFVPADGPVFGDTVTSSEHLAGIN-----FTGSVPTFKRLWKQVAQNLDIYKNFPR 303 Query: 358 IKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN-WSS--SGLL 528 + E G ++ + ++ + A+ GQKCSA S +++ + W GLL Sbjct: 304 VAGECGGKNFHFVHKSADVRSVVTGTI-RSAFEYGGQKCSACSRMYVPDSLWPQIRQGLL 362 Query: 529 EKMKKLSERRKLEDLT 576 + K++ +ED + Sbjct: 363 DVYKQIKVGDPVEDFS 378
>BETB_PSEF5 (Q4K4K8) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 42.7 bits (99), Expect = 0.001 Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 6/157 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K S+ ++ + E GLP Sbjct: 140 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGLPD 199 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILG 399 + + G + L E +P++ FTG + +K+ A L+D + Sbjct: 200 GVFNVLTGSGREVGTWLTE-HPRIEKVSFTGGTDTGKKVMASASSS-SLKDVTMELGGKS 257 Query: 400 P----DVQEVDYISWVCDQDAYACSGQKCSAQSMLFM 498 P D ++D + + SGQ C+ + +F+ Sbjct: 258 PLIIFDDADLDRAADTAMMANFYSSGQVCTNGTRVFV 294
>AL1A1_CHICK (P27463) Retinal dehydrogenase 1 (EC 1.2.1.36) (RalDH1) (RALDH 1)| (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (ALHDII) (ALDH-E1) Length = 509 Score = 42.7 bits (99), Expect = 0.001 Identities = 43/157 (27%), Positives = 67/157 (42%), Gaps = 6/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + + ++ AL GN V+K + + M L+ E G P Sbjct: 167 PVGVCGQIIPWNFPLVMFIWKIAPALCCGNTVVVKPAEQTPLSALYMGSLIKEAGFPPGV 226 Query: 232 VDFINSDGITMNKLLL-EANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G T + + FTGS+ V KL + G R+ LE G I Sbjct: 227 VNIVPGFGPTAGAAISHHMDIDKVSFTGSTEVG-KLIKEAAGKTNLKRVTLELGGKSPNI 285 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 + D ++D + + GQ C A S +F+ + Sbjct: 286 IFADA-DLDEAAEFAHIGLFYHQGQCCIAGSRIFVEE 321
>YM00_YEAST (Q04458) Hypothetical aldehyde dehydrogenase-like protein in| ILV2-ADE17 intergenic region (EC 1.2.1.-) Length = 532 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/101 (34%), Positives = 41/101 (40%), Gaps = 4/101 (3%) Frame = +1 Query: 58 GPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAEDVD 237 G V II PFNFPL + L AL GN VLK M LL G P + Sbjct: 130 GSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQ 189 Query: 238 FINSDGITMNKLLLEANPKMTLFTGSSR----VAEKLAADL 348 + +LL + +TGS R VAEK A L Sbjct: 190 VVQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSL 230
>YHJ9_YEAST (P38694) Hypothetical aldehyde dehydrogenase-like protein in| FIL1-VMA10 intergenic region (EC 1.2.1.-) Length = 644 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 13/154 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA-- 225 P G ++ I +N+P L ++ AL+ GN V+K +V E + L+ +C L A Sbjct: 237 PLGVISSIVSWNYPFHNLLGPIIAALFTGNAIVVKCSEQVVWSSEFFVELIRKC-LEACD 295 Query: 226 EDVDFI--------NSDGITMNKLLLEANPKMTLFTGSSRVAE---KLAADLQGRIKLED 372 ED D + + + N K F GS VA K AA + +E Sbjct: 296 EDPDLVQLCYCLPPTENDDSANYFTSHPGFKHITFIGSQPVAHYILKCAAKSLTPVVVEL 355 Query: 373 AGFDWKILGPDVQEVDYISWVCDQDAYACSGQKC 474 G D I+ + +D +S + + + SGQ C Sbjct: 356 GGKDAFIVLDSAKNLDALSSIIMRGTFQSSGQNC 389
>AL7A1_MALDO (Q9ZPB7) Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3)| (Antiquitin-1) (Matured fruit 60 kDa protein) (MF-60) Length = 507 Score = 42.4 bits (98), Expect = 0.001 Identities = 51/193 (26%), Positives = 83/193 (43%), Gaps = 12/193 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLK---VDSKVSIVMEQMI-RLLHECGL 219 P G V +IT FNFP + AL GN V K V+I + ++I +L + L Sbjct: 153 PLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLVTIAVTKLIAEVLEKNNL 212 Query: 220 PAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEK---LAADLQGRIKLEDAGFDWK 390 PA + + + FTGSS+V K + + G+ LE +G + Sbjct: 213 PAAIFTAFCGGAEIGEAIAKDTRIPLVSFTGSSKVGAKVQQIVTERFGKCLLELSGNNAL 272 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL-- 564 I+ D +V A +GQ+C+ L++H++ +L+K+ L + K+ Sbjct: 273 IVMDDA-DVGLAVRSIFFAAVGTAGQRCTTCRRLYLHES-IYQNVLDKLVGLYNQVKIGD 330 Query: 565 ---EDLTIGPVLT 594 E +GPV T Sbjct: 331 PLEEGTLVGPVHT 343
>AL7A1_MOUSE (Q9DBF1) Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3)| (Antiquitin-1) Length = 510 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 6/158 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLK---VDSKVSIVMEQMI-RLLHECGL 219 P G V IIT FNFP+ + AL GN + K S VS+ + ++I ++L + L Sbjct: 155 PLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLL 214 Query: 220 PAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRI--KLEDAGFDWKI 393 P + + + + FTGS++V +++A +Q R L + G + I Sbjct: 215 PGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAI 274 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + + ++ + A +GQ+C+ LF+H++ Sbjct: 275 IAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHES 312
>YNEI_ECOLI (P76149) Aldehyde dehydrogenase-like protein yneI (EC 1.2.1.-)| Length = 462 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/159 (22%), Positives = 69/159 (43%), Gaps = 3/159 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G + I P+NFPL + + + GN +LK V + + ++ + G+P Sbjct: 126 PLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLKHAPNVMGCAQLIAQVFKDAGIPQGV 185 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKILGP 402 ++N+D +++++ ++ TGS R + A +K LE G D I+ Sbjct: 186 YGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGAAIGAQAGAALKKCVLELGGSDPFIVLN 245 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSS 519 D +++ Y +GQ C+A + + +S+ Sbjct: 246 DA-DLELAVKAAVAGRYQNTGQVCAAAKRFIIEEGIASA 283
>ALDH1_ELEED (Q28399) Aldehyde dehydrogenase, cytosolic 1 (EC 1.2.1.3) (ALDH| class 1) (ETA-crystallin) Length = 501 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 5/156 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G +I P+N P+ + ++ AL GN ++K + + + L+ E G P Sbjct: 159 PIGVCGLIFPWNAPMILLACKIGPALCCGNTVIVKPAEQTPLTALHVASLIKEAGFPPGV 218 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVA----EKLAADLQGRIKLEDAGFDWKIL 396 V+ + G T + + FTGS+ V E A R+ LE + I+ Sbjct: 219 VNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKMIQEAAAKSNLKRVTLELGAKNPCIV 278 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 D ++D Q + GQ C A S LF+ + Sbjct: 279 FADA-DLDSAVEFAHQGVFTNQGQSCIAASKLFVEE 313
>BETB_PSEPK (Q88CW7) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 490 Score = 42.4 bits (98), Expect = 0.001 Identities = 44/207 (21%), Positives = 90/207 (43%), Gaps = 10/207 (4%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G I +N+P++I L + AL GN + K S+ ++ + E GLP Sbjct: 140 REPLGVTVGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGLPN 199 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQG----RIKLEDAGFDW 387 + + G + L E +P++ FTG + +K+ A + +E G Sbjct: 200 GVFNVLTGSGREVGTWLTE-HPRIEKVSFTGGTTTGKKVMASASSSSLKEVTMELGGKSP 258 Query: 388 KILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR--- 558 I+ D ++D + + + SGQ C+ + +F+ ++ + ++++ R Sbjct: 259 LIICADA-DLDKAADIAMMANFYSSGQVCTNGTRVFIPAEMKAAFEAKIAERVARIRVGN 317 Query: 559 -KLEDLTIGPVLTVTTSTMIEHMNNLL 636 + E+ GP+++ +HM ++L Sbjct: 318 PEDENTNFGPLVS------FQHMESVL 338
>AL3B1_RAT (Q5XI42) Aldehyde dehydrogenase 3B1 (EC 1.2.1.5)| Length = 468 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/48 (45%), Positives = 33/48 (68%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMI 195 PFG V II P+N+PL + L+ L+GA+ GN VLK S++S E+++ Sbjct: 104 PFGLVLIIVPWNYPLNLTLVPLVGAIAAGNCVVLK-PSEISKATEKIL 150
>YF19_SCHPO (O14293) Hypothetical aldehyde dehydrogenase-like protein C9E9.09c| (EC 1.2.1.-) Length = 503 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/157 (23%), Positives = 69/157 (43%), Gaps = 5/157 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFP + ++ A+ GN +LK + + + + ECG P Sbjct: 160 PIGVCGQIIPWNFPFLMCAWKIAPAVACGNTIILKTAELTPLSALCLTKFVPECGFPPGV 219 Query: 232 VDFINSDGITM-NKLLLEANPKMTLFTGSSRVAEKL----AADLQGRIKLEDAGFDWKIL 396 ++ ++ DG N + + FTGS+ V + A+ ++ LE G I+ Sbjct: 220 INVLSGDGRRCGNAISSHMDIDKVAFTGSTGVGRMVMRAAASSNLKKVTLELGGKSPNIV 279 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 D ++D + + + SGQ C A S +++ ++ Sbjct: 280 FNDA-DLDSAAVWTNYGIFYNSGQVCCAGSRVYVQED 315
>DMPC_PSEUF (P19059) 2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.-)| (HMSD) Length = 486 Score = 42.4 bits (98), Expect = 0.001 Identities = 38/165 (23%), Positives = 71/165 (43%), Gaps = 5/165 (3%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G ++ R P G + +I+P+N PL + ++ AL GN V+K + + + ++ Sbjct: 135 GAINYAVRRPKGVIGVISPWNLPLLLMTWKVGPALACGNTVVVKPSEETPLTTALLGEVM 194 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEANPKMT--LFTGSSRVAE---KLAADLQGRIKLE 369 G+PA + ++ G L +P + FTG +R E + AA + E Sbjct: 195 QAAGVPAGVYNVVHGFGPDSAGAFLTEHPDVNAITFTGETRTGEAIMRAAAKGVRPVSFE 254 Query: 370 DAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 G + I+ D ++D + +A GQ C L++ + Sbjct: 255 LGGKNAGIVFADC-DLDKAIEGSMRSVFANGGQVCLGTERLYVER 298
>YDCW_ECOLI (P77674) Putative betaine aldehyde dehydrogenase (EC 1.2.1.8)| (BADH) Length = 474 Score = 42.0 bits (97), Expect = 0.002 Identities = 46/175 (26%), Positives = 75/175 (42%), Gaps = 4/175 (2%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G S R P G VA I P+N+PL + +L AL GN VLK + ++ L Sbjct: 129 GHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELA 188 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEANPK--MTLFTGSSRVAEKLAADLQGRIKLE--D 372 + PA ++ + G T+ L +PK M TGS E + + IK + Sbjct: 189 KDI-FPAGVINILFGRGKTVGD-PLTGHPKVRMVSLTGSIATGEHIISHTASSIKRTHME 246 Query: 373 AGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKM 537 G ++ D +++ + Y +GQ C+A ++ K + L+EK+ Sbjct: 247 LGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDT-LVEKL 300
>ALDH_VIBCH (P23240) Aldehyde dehydrogenase (EC 1.2.1.3)| Length = 506 Score = 41.6 bits (96), Expect = 0.002 Identities = 42/160 (26%), Positives = 70/160 (43%), Gaps = 8/160 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFPL + +L AL G VLK + + + ++ ++ + +PA Sbjct: 154 PIGVVGQIIPWNFPLLMAAWKLAPALAAGCTVVLKPAEQTPVSILFLMEIIGDL-IPAGV 212 Query: 232 VDFINSDGITM-NKLLLEANPKMTLFTGSSRVAE---KLAADLQGRIKLEDAGFDWKILG 399 ++ +N G N L FTGS+ + K AAD +E G I Sbjct: 213 INVVNGFGSEAGNALATSQRIDKLAFTGSTEIGNHILKCAADNLIPSTIELGGKSPNIYF 272 Query: 400 PDV--QEVDYISWVCDQD--AYACSGQKCSAQSMLFMHKN 507 PD+ E Y+ + A+ G+ C+ S + +H++ Sbjct: 273 PDIFSHEDQYLDKCIEGALLAFFNQGEVCTCPSRILVHES 312
>AL3B1_MOUSE (Q80VQ0) Aldehyde dehydrogenase 3B1 (EC 1.2.1.5) (Aldehyde| dehydrogenase 7) Length = 468 Score = 41.6 bits (96), Expect = 0.002 Identities = 21/48 (43%), Positives = 33/48 (68%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMI 195 PFG V II P+N+P+ + L+ L+GA+ GN VLK S++S E+++ Sbjct: 104 PFGLVLIIVPWNYPINLTLVPLVGAIAAGNCVVLK-PSEISKATEKIL 150
>ALDH_PSEOL (P12693) Aldehyde dehydrogenase (EC 1.2.1.3)| Length = 483 Score = 41.2 bits (95), Expect = 0.003 Identities = 43/158 (27%), Positives = 68/158 (43%), Gaps = 7/158 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II P+N+P + L+ AL GN V+K S+++ +I + + Sbjct: 120 PKGVCLIIAPWNYPFNLSFGPLVSALAAGNSVVIK-PSELTPHTATLIGSIVREAFSVDL 178 Query: 232 VDFINSDGITMNKLLLEANP-KMTLFTGSSRVAE---KLAADLQGRIKLEDAGFDWKILG 399 V + D +LL A P FTGS RV + + A+ + LE G I+G Sbjct: 179 VAVVEGDAAVSQELL--ALPFDHIFFTGSPRVGKLVMEAASKTLASVTLELGGKSPTIIG 236 Query: 400 PDV---QEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 P + I W ++ +GQ C A +F+H+ Sbjct: 237 PTANLPKAARNIVW----GKFSNNGQTCIAPDHVFVHR 270
>GABD_ECOLI (P25526) Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)| (SSDH) Length = 482 Score = 41.2 bits (95), Expect = 0.003 Identities = 49/199 (24%), Positives = 85/199 (42%), Gaps = 10/199 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G A ITP+NFP + + AL G VLK S+ + L G+PA Sbjct: 146 PIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGV 205 Query: 232 VDFI-NSDGITMNKLLLEANPKMTLFTGSSRVA----EKLAADLQGRIKLEDAGFDWKIL 396 + + S G N+L + FTGS+ + E+ A D++ ++ LE G I+ Sbjct: 206 FNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIK-KVSLELGGNAPFIV 264 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED-- 570 D ++D + +GQ C + L++ ++ EK+++ + + D Sbjct: 265 FDDA-DLDKAVEGALASKFRNAGQTCVCANRLYV-QDGVYDRFAEKLQQAVSKLHIGDGL 322 Query: 571 ---LTIGPVLTVTTSTMIE 618 +TIGP++ +E Sbjct: 323 DNGVTIGPLIDEKAVAKVE 341
>BETB_HALEL (Q9L4K1) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 489 Score = 41.2 bits (95), Expect = 0.003 Identities = 44/205 (21%), Positives = 82/205 (40%), Gaps = 8/205 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G + I +N+P++I + AL GN V K + ++ + E GLP Sbjct: 140 REPLGVIGAIGAWNYPIQIACWKAAPALAAGNAIVFKPSEVTPLTALKLAEIFTEAGLPD 199 Query: 226 EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGR----IKLEDAGFDWKI 393 + + DG L FTG +K+ A G + +E G I Sbjct: 200 GVFNVVQGDGRVGAMLTEHEGIAKVSFTGEVGTGKKVMAAAGGSTLKDVTMELGGKSPLI 259 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMH---KNWSSSGLLEKMKKLSERRKL 564 + D ++D + + SGQ C+ + +F+ K + L+E++ ++ + Sbjct: 260 VFADA-DLDRAADAAMMANFYSSGQICTNGTRVFVERSAKEAFEAKLVERVARIKAGDPM 318 Query: 565 E-DLTIGPVLTVTTSTMIEHMNNLL 636 + + GP+++ EH +L Sbjct: 319 DPSVNFGPLVS------FEHQEKVL 337
>BADH_GADCA (P56533) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 503 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/169 (23%), Positives = 67/169 (39%), Gaps = 3/169 (1%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G A I +N+P I + AL GN V K + + + HE G+P Sbjct: 153 REPLGVCAGILAWNYPFMIAAWKCAPALACGNAVVFKPSPMTPVTGVILAEIFHEAGVPV 212 Query: 226 EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEK---LAADLQGRIKLEDAGFDWKIL 396 V+ + T + L N FTGS +K ++A + LE G ++ Sbjct: 213 GLVNVVQGGAETGSLLCHHPNVAKVSFTGSVPTGKKVMEMSAKTVKHVTLELGGKSPLLI 272 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKK 543 D + + + + + GQ C+ + +F+ + L E +K+ Sbjct: 273 FKDCELENAVRGALMAN-FLTQGQVCTNGTRVFVQREIMPQFLEEVVKR 320
>ALDH_ASPNG (P41751) Aldehyde dehydrogenase (EC 1.2.1.3) (ALDDH)| Length = 497 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 6/174 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ A+ GN V+K + + ++ E G+PA Sbjct: 155 PIGVCGQIIPWNFPLLMWAWKIGPAIATGNTVVIKTAEQTPLSGLYAANVIKEAGIPAGV 214 Query: 232 VDFINSDG-ITMNKLLLEANPKMTLFTGSSRVAEKL----AADLQGRIKLEDAGFDWKIL 396 V+ I+ G + + + + FTGS+ V + A ++ LE G I+ Sbjct: 215 VNVISGFGRVAGSAISHHMDIDKVAFTGSTLVGRTILQAAAKSNLKKVTLELGGKSPNIV 274 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEK-MKKLSER 555 D + ISW + + GQ C A S + + + G+ +K + +L ER Sbjct: 275 FNDADIDNAISW-ANFGIFYNHGQCCCAGSRILVQE-----GIYDKFIARLKER 322
>THCA_RHOER (P46369) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3)| Length = 505 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFP+ + + +L AL GN VLK + + + +I ++ + LPA Sbjct: 154 PLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPVSILHLIGIIGDL-LPAGV 212 Query: 232 VDFINSDGITMNKLLLEA-NPKMTLFTGSS 318 ++ +N G+ K L + K FTG + Sbjct: 213 LNIVNGFGVEAGKPLASSPRIKKIAFTGET 242
>ALDH1_MACPR (Q29490) Aldehyde dehydrogenase, cytosolic 1 (EC 1.2.1.3) (ALDH| class 1) (ETA-crystallin) Length = 501 Score = 40.4 bits (93), Expect = 0.005 Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 5/156 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+N P+ + ++ AL GN ++K + + + L+ E G P Sbjct: 159 PIGVCGQIFPWNAPMILLACKIGPALCCGNTVIVKPAEQTPLTALHVASLIKEAGFPPGV 218 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVA----EKLAADLQGRIKLEDAGFDWKIL 396 V+ + G T + + FTGS+ V E A R+ LE + I+ Sbjct: 219 VNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKMIQEAAAKSNLKRVTLELGAKNPCIV 278 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 D ++D Q + GQ C A S LF+ + Sbjct: 279 FADA-DLDSAVEFAHQGVFTNQGQSCIAASKLFVEE 313
>AL3A2_RAT (P30839) Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde| dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10) Length = 484 Score = 40.4 bits (93), Expect = 0.005 Identities = 50/180 (27%), Positives = 76/180 (42%), Gaps = 17/180 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA-- 225 P G V II +N+P + L L+GA+ GN ++ K S + E ++L E LP Sbjct: 101 PLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIV----KPSELSENTAKILAEL-LPQYL 155 Query: 226 -EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGP 402 +D+ I + G+ LL L+TG++ V G+I +E A K L P Sbjct: 156 DQDLYMIVNGGVEETTELLRQRFDHILYTGNTAV---------GKIVMEAAA---KHLTP 203 Query: 403 DVQEVD-----YISWVCDQDA---------YACSGQKCSAQSMLFMHKNWSSSGLLEKMK 540 E+ YI CD D Y GQ C A + + S +++K+K Sbjct: 204 VTLELGGKSPCYIDRDCDLDVACRRITWGKYMNCGQTCIAPDYILCEAS-SQDQIVQKIK 262
>ALDH_DEIRA (Q9RYG9) Aldehyde dehydrogenase (EC 1.2.1.3)| Length = 515 Score = 40.4 bits (93), Expect = 0.005 Identities = 40/128 (31%), Positives = 60/128 (46%), Gaps = 5/128 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFPL + + +L AL GN VLK + + ++ L+ + LP Sbjct: 164 PLGVVGQIIPWNFPLLMGVWKLAPALAAGNAVVLKPAEQTPASIMVLMELIADL-LPEGV 222 Query: 232 VDFINSDGITMNKLLLEANPKMT--LFTG---SSRVAEKLAADLQGRIKLEDAGFDWKIL 396 V+ +N G+ K L ++P++ FTG + R+ AAD + LE G I Sbjct: 223 VNVVNGFGLEAGK-PLASSPRIAKIAFTGETNTGRLIMGYAADNLIPVTLELGGKSPNIF 281 Query: 397 GPDVQEVD 420 DV D Sbjct: 282 FDDVMMED 289
>HPCC_ECOLI (P42269) 5-carboxymethyl-2-hydroxymuconate semialdehyde| dehydrogenase (EC 1.2.1.-) (CHMS dehydrogenase) Length = 468 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/153 (18%), Positives = 68/153 (44%), Gaps = 1/153 (0%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G A+++P+N P ++ L +G VLK+ + +++ L E G+PA Sbjct: 137 PVGVCALVSPWNVPFMTATWKVAPCLALGITAVLKMSELSPLTADRLGELALEAGIPAGV 196 Query: 232 VDFINSDGITMNKLLLEANP-KMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 ++ + G T L+ + + FTG + + + + + G +L + Sbjct: 197 LNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKKYSMELGGKSPVLIFED 256 Query: 409 QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 +++ ++ +G++C+A S +F+ ++ Sbjct: 257 ADIERALDAALFTIFSINGERCTAGSRIFIQQS 289
>BETB_BURPS (Q63KK8) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 489 Score = 40.0 bits (92), Expect = 0.006 Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 6/159 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G A I +N+P++I + AL GN + K + ++ + E G+PA Sbjct: 140 REPLGVCAGIGAWNYPIQIACWKSAPALAAGNAMIFKPSEVTPLSALKLAEIYTEAGVPA 199 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILG 399 + + DG LL A+P + FTG +K+ + L G L++ + Sbjct: 200 GVFNVVQGDGSV--GALLSAHPGIAKVSFTGGVETGKKVMS-LAGASSLKEVTMELGGKS 256 Query: 400 P----DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 P D ++D + + + +GQ C+ + +F+ + Sbjct: 257 PLIVFDDADLDRAADIAVTANFFSAGQVCTNGTRVFVQQ 295
>BETB_BURMA (Q62CH7) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 489 Score = 40.0 bits (92), Expect = 0.006 Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 6/159 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G A I +N+P++I + AL GN + K + ++ + E G+PA Sbjct: 140 REPLGVCAGIGAWNYPIQIACWKSAPALAAGNAMIFKPSEVTPLSALKLAEIYTEAGVPA 199 Query: 226 EDVDFINSDGITMNKLLLEANPKM--TLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILG 399 + + DG LL A+P + FTG +K+ + L G L++ + Sbjct: 200 GVFNVVQGDGSV--GALLSAHPGIAKVSFTGGVETGKKVMS-LAGASSLKEVTMELGGKS 256 Query: 400 P----DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 P D ++D + + + +GQ C+ + +F+ + Sbjct: 257 PLIVFDDADLDRAADIAVTANFFSAGQVCTNGTRVFVQQ 295
>CROM_OCTDO (P30841) Omega-crystallin| Length = 495 Score = 40.0 bits (92), Expect = 0.006 Identities = 43/179 (24%), Positives = 78/179 (43%), Gaps = 6/179 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G +I P+N+P+ + ++ AL GN V+K + + L+ E G P Sbjct: 152 PVGICGLIIPWNYPMLMMTWKMAPALSCGNCIVVKPAEQTPLTALYCASLMEEAGFPPGV 211 Query: 232 VDFINSDG-ITMNKLLLEANPKMTLFTGSSRVAEKLAADLQG-----RIKLEDAGFDWKI 393 V+ + G I + + FTGS+ V KL G R LE +G + Sbjct: 212 VNVVPGYGTICGQSISSHLDINKVSFTGSTEVG-KLVMQAAGSSNLKRCSLELSGKCPVV 270 Query: 394 LGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 + PD ++D+ + A+ GQ + S ++H++ +++ + + RRK+ D Sbjct: 271 VFPDT-DLDFAVQQAHEAAFQNMGQCRWSGSRAYVHESIYEE-FVKRSVEQATRRKIGD 327
>AL7A1_HUMAN (P49419) Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3)| (Antiquitin-1) Length = 510 Score = 40.0 bits (92), Expect = 0.006 Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 10/162 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLK---VDSKVSIVMEQMI-RLLHECGL 219 P G V IIT FNFP+ + A+ GN + K S +S+ + ++I ++L + L Sbjct: 155 PVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKL 214 Query: 220 PAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQ---GRIKLEDAGFDWK 390 P + + + FTGS++V +++ +Q GR LE G + Sbjct: 215 PGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAI 274 Query: 391 ILGPDVQEVDYISWVCDQDAYAC---SGQKCSAQSMLFMHKN 507 I D +S V +A +GQ+C+ LF+H++ Sbjct: 275 IAFEDAD----LSLVVPSALFAAVGTAGQRCTTARRLFIHES 312
>AL7A1_PEA (P25795) Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3)| (Turgor-responsive protein 26G) (Antiquitin-1) Length = 507 Score = 39.7 bits (91), Expect = 0.008 Identities = 47/205 (22%), Positives = 88/205 (42%), Gaps = 12/205 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHEC----GL 219 P G V +IT FNFP + AL GN V K ++ + +L+ E L Sbjct: 153 PLGIVGVITAFNFPCAVLGWNACIALVGGNTVVWKGAPTTPLITVAVTKLIAEVFERNNL 212 Query: 220 PAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRV---AEKLAADLQGRIKLEDAGFDWK 390 P + + + + + FTGSS+V ++ + G+ LE +G + Sbjct: 213 PGAIFTALCGGADIGHAIAKDTRIPLVSFTGSSKVGALVQQTVSQRFGKTLLELSGNN-A 271 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL-- 564 I+ D ++ A +GQ+C+ L++H++ + +LE++ L ++ K+ Sbjct: 272 IIVMDDADITLAVRSIFFAAVGTAGQRCTTCRRLYLHES-VYANVLEQLTALYKQVKIGN 330 Query: 565 ---EDLTIGPVLTVTTSTMIEHMNN 630 E +GP + T + +E+ N Sbjct: 331 PLEEGTLVGP---LHTRSAVENFKN 352
>ALDH_EMENI (P08157) Aldehyde dehydrogenase (EC 1.2.1.3) (ALDDH)| Length = 497 Score = 39.7 bits (91), Expect = 0.008 Identities = 48/204 (23%), Positives = 87/204 (42%), Gaps = 11/204 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I P+NFPL + ++ A+ GN VLK + + +L+ E PA Sbjct: 154 PVGVCGQIIPWNFPLLMWSWKIGPAVAAGNTVVLKTAQQTPLSALYAAKLIKEAPFPAGV 213 Query: 232 VDFINSDGITMNKLL-LEANPKMTLFTGSSRVA----EKLAADLQGRIKLEDAGFDWKIL 396 ++ I+ G T + + FTGS+ V + A ++ LE G I+ Sbjct: 214 INVISGFGRTAGAAISSHMDIDKVAFTGSTLVGPTILQAAAKSNLKKVTLELGGKSPNIV 273 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL---- 564 D + ISW + + GQ C A S + + + + + K+ +++ K+ Sbjct: 274 FDDADIDNAISW-ANFGIFFNHGQCCCAGSRILVQEGIYDK-FVARFKERAQKNKVGNPF 331 Query: 565 -EDLTIGP-VLTVTTSTMIEHMNN 630 +D GP V + ++E++N+ Sbjct: 332 EQDTFQGPQVSQLQFDRIMEYINH 355
>ALDA_ECOLI (P25553) Aldehyde dehydrogenase A (EC 1.2.1.22) (Lactaldehyde| dehydrogenase) (Glycolaldehyde dehydrogenase) (EC 1.2.1.21) Length = 478 Score = 39.7 bits (91), Expect = 0.008 Identities = 53/220 (24%), Positives = 89/220 (40%), Gaps = 15/220 (6%) Frame = +1 Query: 4 RHEGKXVGQMSNG-----YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSK 168 R+EG+ + G ++ G I P+NFP + ++ AL GN V+K Sbjct: 120 RYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEF 179 Query: 169 VSIVMEQMIRLLHECGLPAEDVDFINSDGITMNKLLLEANPK--MTLFTGSSRVAEKL-- 336 +++ E GLP + + G T+ + L NPK M TGS EK+ Sbjct: 180 TPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQ-ELAGNPKVAMVSMTGSVSAGEKIMA 238 Query: 337 -AADLQGRIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK--- 504 AA ++ LE G I+ D + + D SGQ C+ +++ K Sbjct: 239 TAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVIN-SGQVCNCAERVYVQKGIY 297 Query: 505 NWSSSGLLEKMKKLSERRKLE--DLTIGPVLTVTTSTMIE 618 + + L E M+ + E D+ +GP++ +E Sbjct: 298 DQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAALERVE 337
>BETB_ECO57 (Q7AH91) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 489 Score = 39.3 bits (90), Expect = 0.010 Identities = 46/203 (22%), Positives = 81/203 (39%), Gaps = 5/203 (2%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K + ++ + E GLP Sbjct: 139 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPD 198 Query: 226 EDVDFINSDGITMNKLLLE-ANPKMTLFTG----SSRVAEKLAADLQGRIKLEDAGFDWK 390 + + G + L E FTG +V AA + +E G Sbjct: 199 GVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPL 258 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 I+ D ++D + + + SGQ C+ + +F+ ++ +K+ ER + D Sbjct: 259 IVFDDA-DLDLAADIAMMANFFSSGQVCTNGTRVFVPAK-CNAAFEQKILARVERIRAGD 316 Query: 571 LTIGPVLTVTTSTMIEHMNNLLK 639 + P H +N+L+ Sbjct: 317 V-FDPQTNFGPLVSFPHRDNVLR 338
>DHA2_RALEU (P46368) Acetaldehyde dehydrogenase 2 (EC 1.2.1.3) (Acetaldehyde| dehydrogenase II) (ACDH-II) Length = 506 Score = 39.3 bits (90), Expect = 0.010 Identities = 49/198 (24%), Positives = 86/198 (43%), Gaps = 13/198 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGN----KPVLKVDSKVSIVMEQMIRLLHECGL 219 P G V I P+NFPL + +L AL GN KP + + + ++ME + L L Sbjct: 154 PLGVVGQIIPWNFPLLMATWKLAPALAAGNCVVLKPAEQTPASILVLMEVIGDL-----L 208 Query: 220 PAEDVDFINSDGITMNKLLLEANPKMT--LFTG---SSRVAEKLAADLQGRIKLEDAGFD 384 P V+ IN G+ K L ++P+++ FTG + R+ + A+ + LE G Sbjct: 209 PPGVVNVINGFGLEAGK-PLASSPRISKVAFTGETTTGRLIMQYASQNLIPVTLELGGKS 267 Query: 385 WKILGPDVQEVDYISWVCDQDAYAC----SGQKCSAQSMLFMHKNWSSSGLLEKMKKLSE 552 I DV D + + +A G+ C+ S + ++ + +K+++ Sbjct: 268 PNIFFEDVLAADDAFFDKALEGFAMFALNQGEVCTCPSRALIQESIYDRFMERALKRVAA 327 Query: 553 RRKLEDLTIGPVLTVTTS 606 R+ L G ++ S Sbjct: 328 IRQGHPLDTGTMIGAQAS 345
>AL3A1_HUMAN (P30838) Aldehyde dehydrogenase, dimeric NADP-preferring (EC| 1.2.1.5) (ALDH class 3) (ALDHIII) Length = 453 Score = 39.3 bits (90), Expect = 0.010 Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 15/179 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +I +N+P + + ++GA+ GN VLK S++S M ++ + L + Sbjct: 104 PLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLK-PSELSENMASLLATIIPQYLDKDL 162 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDVQ 411 IN G+ LL+ L+TGS+ V G+I + A K L P Sbjct: 163 YPVING-GVPETTELLKERFDHILYTGSTGV---------GKIIMTAAA---KHLTPVTL 209 Query: 412 EVD-----YISWVCDQDAYAC----------SGQKCSAQSMLFMHKNWSSSGLLEKMKK 543 E+ Y+ CD D AC SGQ C A + + + ++EK+KK Sbjct: 210 ELGGKSPCYVDKNCDLDV-ACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQ-IVEKLKK 266
>AL3A1_MOUSE (P47739) Aldehyde dehydrogenase, dimeric NADP-preferring (EC| 1.2.1.5) (ALDH class 3) (Dioxin-inducible aldehyde dehydrogenase 3) Length = 453 Score = 38.9 bits (89), Expect = 0.013 Identities = 48/179 (26%), Positives = 78/179 (43%), Gaps = 15/179 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +I +N+P + + ++GA+ GN VLK S+VS M ++ L + +D Sbjct: 104 PLGVVLVIGAWNYPFNLTIQPMVGAIAAGNAVVLK-PSEVSDHMADLLSTLIPQYMD-KD 161 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDVQ 411 + + G+ LL+ ++TGS+ V G+I + A K L P Sbjct: 162 LYPVIKGGVPETTELLKEKFDHIMYTGSTAV---------GKIVMAAAA---KHLTPVTL 209 Query: 412 EVD-----YISWVCDQDAYAC----------SGQKCSAQSMLFMHKNWSSSGLLEKMKK 543 E+ Y+ CD D AC SGQ C A + + + ++EK+KK Sbjct: 210 ELGGKSPCYVDKDCDLDV-ACRRIAWGKFMNSGQTCVAPDYILCDPSIQNE-IVEKLKK 266
>ALDA_STAES (Q8CN24) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 497 Score = 38.9 bits (89), Expect = 0.013 Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 5/178 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + +L AL GN V++ S + + ++ ++ E LP Sbjct: 149 PVGVVGAVVAWNFPILLASWKLGPALAAGNTVVIQPSSSTPLSLIELAKIFQEV-LPKGV 207 Query: 232 VDFINSDGITMNKLLL--EANPKMTLFTGSSRVAEKLAADLQGRI---KLEDAGFDWKIL 396 V+ + G + E K++ FTGS+ V +A RI LE G I+ Sbjct: 208 VNVLTGKGSESGDAIFHHEGVDKLS-FTGSTDVGYGVAQAGAERIVPTTLELGGKSANII 266 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 D I V G+ CSA S L + + LL K+K+ E K+ D Sbjct: 267 FDDANLEQVIEGV-QLGILFNQGEVCSAGSRLLVQSSIYDE-LLPKLKEAFENIKVGD 322
>ALDA_STAEQ (Q5HLA3) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 497 Score = 38.9 bits (89), Expect = 0.013 Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 5/178 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + +L AL GN V++ S + + ++ ++ E LP Sbjct: 149 PVGVVGAVVAWNFPILLASWKLGPALAAGNTVVIQPSSSTPLSLIELAKIFQEV-LPKGV 207 Query: 232 VDFINSDGITMNKLLL--EANPKMTLFTGSSRVAEKLAADLQGRI---KLEDAGFDWKIL 396 V+ + G + E K++ FTGS+ V +A RI LE G I+ Sbjct: 208 VNVLTGKGSESGDAIFHHEGVDKLS-FTGSTDVGYGVAQAGAERIVPTTLELGGKSANII 266 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 D I V G+ CSA S L + + LL K+K+ E K+ D Sbjct: 267 FDDANLEQVIEGV-QLGILFNQGEVCSAGSRLLVQSSIYDE-LLPKLKEAFENIKVGD 322
>BETB_ECOLI (P17445) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 489 Score = 38.9 bits (89), Expect = 0.013 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 5/156 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K + ++ + E GLP Sbjct: 139 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPD 198 Query: 226 EDVDFINSDGITMNKLLLE-ANPKMTLFTG----SSRVAEKLAADLQGRIKLEDAGFDWK 390 + + G + L E FTG +V AA + +E G Sbjct: 199 GVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPL 258 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM 498 I+ D ++D + + + SGQ C+ + +F+ Sbjct: 259 IVFDDA-DLDLAADIAMMANFFSSGQVCTNGTRVFV 293
>AL3A2_MOUSE (P47740) Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde| dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10) Length = 484 Score = 38.9 bits (89), Expect = 0.013 Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 17/181 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA-- 225 P G V II +N+P + + L+GA+ GN ++ K S + E ++L E LP Sbjct: 101 PLGVVLIIGAWNYPFVLTMQPLVGAIAAGNAAIV----KPSELSENTAKILAEL-LPQYL 155 Query: 226 -EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGP 402 +D+ I + GI LL+ L+TG++ V G+I +E A K L P Sbjct: 156 DQDLYAIVNGGIPETTELLKQRFDHILYTGNTAV---------GKIVMEAAA---KHLTP 203 Query: 403 DVQEVD-----YISWVCDQDA---------YACSGQKCSAQSMLFMHKNWSSSGLLEKMK 540 E+ YI CD D Y GQ C A + + + +++K+K Sbjct: 204 VTLELGGKSPCYIDRDCDLDVACRRVAWGKYMNCGQTCIAPDYILCEASLQNQ-IVQKIK 262 Query: 541 K 543 + Sbjct: 263 E 263
>CALB_PSEAE (Q9I6C8) Probable coniferyl aldehyde dehydrogenase (EC 1.2.1.68)| (CALDH) Length = 476 Score = 38.9 bits (89), Expect = 0.013 Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 6/129 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +I P+N+PL + + L GAL GN+ ++K+ + LL P + Sbjct: 119 PLGVVGVIVPWNYPLFLSIGPLTGALAAGNRVMIKMSESTPATGRLLKDLLARI-FPEDQ 177 Query: 232 VDFINSD---GITMNKLLLEANPKMTLFTGSSRVAE---KLAADLQGRIKLEDAGFDWKI 393 V + + G+ +KL + LFTG++ V + + AA+ + LE G I Sbjct: 178 VAVVLGEVDVGVAFSKLPFD----HLLFTGATSVGKHVMRAAAENLTPVTLELGGKSPAI 233 Query: 394 LGPDVQEVD 420 + V D Sbjct: 234 VSDSVPMKD 242
>PUT2_EMENI (Q9P8I0) Delta-1-pyrroline-5-carboxylate dehydrogenase,| mitochondrial precursor (EC 1.5.1.12) (P5C dehydrogenase) Length = 572 Score = 38.5 bits (88), Expect = 0.017 Identities = 53/208 (25%), Positives = 88/208 (42%), Gaps = 17/208 (8%) Frame = +1 Query: 43 YRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLP 222 YR G V I+PFNF L AL MGN V K + ++L E GLP Sbjct: 201 YRPLEGFVYAISPFNFTAIGGNLAGAPAL-MGNVVVWKPSPSAIASNWLVHQILLEAGLP 259 Query: 223 AEDVDFINSDGITMNKLLLEANPKMTL-FTGSSRVAEKLAADLQGRIKL----------- 366 + F+ + + K +L+ L FTGS+ V L + R+ Sbjct: 260 KNVIQFVPGEAEEVTKTVLDHPDFAALHFTGSTNVFRNLYGQISTRVAAGKYRSYPRIVG 319 Query: 367 EDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKL 546 E G ++ ++ ++ + + A+ GQKCSA S +++ + + S LE++ Sbjct: 320 ETGGKNFHLIHKSA-DIRNAAVQTVRGAFEYQGQKCSATSRVYVASSIADS-FLEQVASE 377 Query: 547 SERRKL---EDLT--IGPVLTVTTSTMI 615 ++ K+ D T GPV+ + T + Sbjct: 378 AKSLKVGPPSDFTNFCGPVIHEASFTKL 405
>BETB2_RHIME (Q92YD2) Betaine aldehyde dehydrogenase 2 (EC 1.2.1.8) (BADH 2)| Length = 481 Score = 38.5 bits (88), Expect = 0.017 Identities = 40/190 (21%), Positives = 78/190 (41%), Gaps = 7/190 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G I +N+P++I + AL GN + K + ++ +L E GLP Sbjct: 142 REPLGVCLGIGAWNYPIQIAAWKAAPALACGNAMIFKPSEVTPLSALKLAEILTEAGLPP 201 Query: 226 EDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKIL 396 + + G +L TGS + ++A+ I+ +E G I+ Sbjct: 202 GVFNIVQGAGDVGAELATHPAIAKVSLTGSVKTGARVASAAMAGIRPVTMELGGKSALIV 261 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR----KL 564 D +S + Y+ +GQ CS + +F+ + + L + +++ + Sbjct: 262 FDDADVEAAVSGAILGNFYS-AGQICSNGTRVFLQRGIREAFLARLLARVAALKIGDPMD 320 Query: 565 EDLTIGPVLT 594 E+ IGP+++ Sbjct: 321 EETDIGPLVS 330
>ALDH_STRCO (Q9RJZ6) Probable aldehyde dehydrogenase (EC 1.2.1.3)| Length = 507 Score = 38.5 bits (88), Expect = 0.017 Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 5/137 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G VA I P+NFP+ + +L AL GN VLK + + + L+ + LP Sbjct: 155 PLGVVAQIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASIHYWLSLVADL-LPPGV 213 Query: 232 VDFINSDGITMNKLLLEANPKM--TLFTG---SSRVAEKLAADLQGRIKLEDAGFDWKIL 396 ++ +N G+ K L ++P++ FTG + R+ + A++ + LE G I Sbjct: 214 LNVVNGFGVEAGK-PLASSPRVAKVAFTGETTTGRLIMQYASENIKPVTLELGGKSPNIF 272 Query: 397 GPDVQEVDYISWVCDQD 447 DV W D D Sbjct: 273 FEDV-------WARDDD 282
>FTHFD_RAT (P28037) 10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6)| (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1) (FBP-CI) Length = 902 Score = 38.1 bits (87), Expect = 0.023 Identities = 42/187 (22%), Positives = 79/187 (42%), Gaps = 9/187 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I+ P+N+PL + + L GN V+K + + L + G+P Sbjct: 563 PVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGV 622 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSSRVAEKL----AADLQGRIKLEDAGFDWKIL 396 V+ + G + + L + + + FTGS+ V + + A ++ LE G I+ Sbjct: 623 VNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLII 682 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK---NWSSSGLLEKMKKLSERRKLE 567 D +++ + + G+ C A LF+ + N ++E+++K+ LE Sbjct: 683 FADC-DLNKAVQMGMSSVFFNKGENCIAAGRLFVEESIHNQFVQKVVEEVEKMKIGNPLE 741 Query: 568 -DLTIGP 585 D GP Sbjct: 742 RDTNHGP 748
>AL7A1_ARATH (Q9SYG7) Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3)| (Antiquitin-1) Length = 508 Score = 38.1 bits (87), Expect = 0.023 Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 11/207 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLK---VDSKVSIVMEQMI-RLLHECGL 219 P G V +IT FNFP + AL GN V K ++I M +++ +L + L Sbjct: 154 PLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLVAEVLEKNNL 213 Query: 220 PAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADL---QGRIKLEDAGFDWK 390 P + + + + FTGSSRV + + G+ LE +G + Sbjct: 214 PGAIFTAMCGGAEIGEAIAKDTRIPLVSFTGSSRVGSMVQQTVNARSGKTLLELSGNN-A 272 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSERRK 561 I+ D ++ + A +GQ+C+ L +H++ LL K++ Sbjct: 273 IIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHESVYDKVLEQLLTSYKQVKIGNP 332 Query: 562 LEDLT-IGPVLTVTTSTMIEHMNNLLK 639 LE T +GP+ T + E ++K Sbjct: 333 LEKGTLLGPLHTPESKKNFEKGIEVIK 359
>BETB1_RHIME (P54222) Betaine aldehyde dehydrogenase 1 (EC 1.2.1.8) (BADH 1)| Length = 487 Score = 38.1 bits (87), Expect = 0.023 Identities = 45/180 (25%), Positives = 74/180 (41%), Gaps = 4/180 (2%) Frame = +1 Query: 25 GQMSNGYRWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLL 204 G + R P G I +N+P +I + AL GN V K + ++ +L Sbjct: 133 GDFAYTKRVPLGVCVGIGAWNYPQQIACWKGAPALVAGNAMVFKPSENTPLGALKIAEIL 192 Query: 205 HECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGS----SRVAEKLAADLQGRIKLED 372 E GLP + I D T L+ + TGS +VA AA+L+ + +E Sbjct: 193 IEAGLPKGLFNVIQGDRATGPLLVNHPDVAKVSLTGSVPTGKKVAGAAAAELK-HVTMEL 251 Query: 373 AGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSE 552 G I+ D I + Y+ +GQ CS + +F+ + L ++K+ +E Sbjct: 252 GGKSPLIVFDDADLESAIGGAMLGNFYS-TGQVCSNGTRVFVQRK-IKEPFLARLKERTE 309
>ALDH_PSESP (P33008) Probable aldehyde dehydrogenase (EC 1.2.1.3)| Length = 488 Score = 37.7 bits (86), Expect = 0.030 Identities = 44/170 (25%), Positives = 75/170 (44%), Gaps = 10/170 (5%) Frame = +1 Query: 28 QMSNGYRWPFGPVAIITPFNFPLEIPLL---QLMGALYMGNKPVLKVDSKVSIVMEQMIR 198 ++S R P G V I P+N+P+ I + + +G + + + + ++IR Sbjct: 147 RLSKTVREPLGVVVAIVPWNYPVSIAFVKPDRRVGCRKHADSQAGADHAADYLRIGELIR 206 Query: 199 LLHECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSS----RVAEKLAADLQGRIKL 366 LPA ++ + + L A+ FTGSS VA AADL+ R+ L Sbjct: 207 ----DALPAGVINVLAGNDDLGPWLTGHADVAKISFTGSSVTGRHVARSAAADLK-RLTL 261 Query: 367 EDAGFDWKILGPDVQE---VDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 E G D ++ D V+ + W A+ +GQ C A L++H++ Sbjct: 262 ELGGNDAAVVMADSLSDAVVERVFW----SAFTNAGQICMATKRLYIHES 307
>BETB_ECOL6 (Q8FKI8) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 489 Score = 37.7 bits (86), Expect = 0.030 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 5/156 (3%) Frame = +1 Query: 46 RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 R P G VA I +N+P++I L + AL GN + K + ++ + E GLP Sbjct: 139 REPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPD 198 Query: 226 EDVDFINSDGITMNKLLLE-ANPKMTLFTG----SSRVAEKLAADLQGRIKLEDAGFDWK 390 + + G + L + FTG +V AA + +E G Sbjct: 199 GVFNVLPGVGAETGQYLTDHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPL 258 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM 498 I+ D ++D + + + SGQ C+ + +F+ Sbjct: 259 IVFDDA-DLDLAADIAMMANFFSSGQVCTNGTRVFV 293
>AL3A1_RAT (P11883) Aldehyde dehydrogenase, dimeric NADP-preferring (EC| 1.2.1.5) (ALDH class 3) (Tumor-associated aldehyde dehydrogenase) (HTC-ALDH) Length = 452 Score = 37.7 bits (86), Expect = 0.030 Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 15/179 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V +I +N+P + + ++GA+ GN +LK S+VS M ++ L + ++ Sbjct: 103 PLGVVLVIGAWNYPFNLTIQPMVGAVAAGNAVILK-PSEVSGHMADLLATLIPQYMD-QN 160 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDVQ 411 + + G+ LL+ ++TGS+ V G+I + A K L P Sbjct: 161 LYLVVKGGVPETTELLKERFDHIMYTGSTAV---------GKIVMAAAA---KHLTPVTL 208 Query: 412 EVD-----YISWVCDQDAYAC----------SGQKCSAQSMLFMHKNWSSSGLLEKMKK 543 E+ Y+ CD D AC SGQ C A + + + ++EK+KK Sbjct: 209 ELGGKSPCYVDKDCDLDV-ACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQ-IVEKLKK 265
>ALDA_STAHJ (Q4L919) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 497 Score = 37.4 bits (85), Expect = 0.039 Identities = 45/178 (25%), Positives = 76/178 (42%), Gaps = 5/178 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + +L AL GN V++ S + + ++ ++ E LP Sbjct: 149 PVGVVGAVVAWNFPILLASWKLAPALAAGNTIVIQPSSSTPLSLIELAKIFQEV-LPKGV 207 Query: 232 VDFINSDGITMNKLLL--EANPKMTLFTGSSRVAEKLAADLQGRI---KLEDAGFDWKIL 396 V+ + G + E K++ FTGS+ V +A RI LE G I+ Sbjct: 208 VNVLTGKGSESGDAIFNHEGVNKLS-FTGSTDVGYGVAKAGAERIVPTTLELGGKSANII 266 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED 570 D +D + G+ CSA S L + + ++ K+K+ E K+ D Sbjct: 267 FDDA-NLDQVVEGAQLGILFNQGEVCSAGSRLLVQSSIYDK-VMPKLKEAFENIKVGD 322
>BETB_BRUSU (Q8G1Z9) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 487 Score = 37.4 bits (85), Expect = 0.039 Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 7/181 (3%) Frame = +1 Query: 73 ITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAEDVDFINSD 252 I +N+P++I + AL MGN + K + + E GLP + + Sbjct: 148 IGAWNYPIQIAAWKSAPALAMGNAFIFKPSENTPLSALALAEAYKEAGLPDGLFNVVQGY 207 Query: 253 GITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKILGPDVQEVDY 423 G L+ TGS ++ A ++K +E G I+ D Sbjct: 208 GDVGAALVNHRLTAKVSLTGSVPTGRRIMAQAGEQLKHVTMELGGKSPLIVFDDADLESA 267 Query: 424 ISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSERRKLEDLT-IGPVL 591 I + Y+ +GQ CS + +F+HKN L+E+ +K+ ++ T +GP++ Sbjct: 268 IGGAMLGNFYS-TGQVCSNGTRVFVHKNIRERFIERLVERTRKIRIGDPFDEATQMGPLI 326 Query: 592 T 594 + Sbjct: 327 S 327
>BETB_BRUME (Q8YFY0) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 487 Score = 37.4 bits (85), Expect = 0.039 Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 7/181 (3%) Frame = +1 Query: 73 ITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAEDVDFINSD 252 I +N+P++I + AL MGN + K + + E GLP + + Sbjct: 148 IGAWNYPIQIAAWKSAPALAMGNAFIFKPSENTPLSALALAEAYKEAGLPDGLFNVVQGY 207 Query: 253 GITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKILGPDVQEVDY 423 G L+ TGS ++ A ++K +E G I+ D Sbjct: 208 GDVGAALVNHRLTAKVSLTGSVPTGRRIMAQAGEQLKHVTMELGGKSPLIVFDDADLESA 267 Query: 424 ISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSERRKLEDLT-IGPVL 591 I + Y+ +GQ CS + +F+HKN L+E+ +K+ ++ T +GP++ Sbjct: 268 IGGAMLGNFYS-TGQVCSNGTRVFVHKNIRERFIERLVERTRKIRIGDPFDEATQMGPLI 326 Query: 592 T 594 + Sbjct: 327 S 327
>BETB_BRUAB (Q57EI0) Betaine aldehyde dehydrogenase (EC 1.2.1.8) (BADH)| Length = 487 Score = 37.4 bits (85), Expect = 0.039 Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 7/181 (3%) Frame = +1 Query: 73 ITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAEDVDFINSD 252 I +N+P++I + AL MGN + K + + E GLP + + Sbjct: 148 IGAWNYPIQIAAWKSAPALAMGNAFIFKPSENTPLSALALAEAYKEAGLPDGLFNVVQGY 207 Query: 253 GITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKILGPDVQEVDY 423 G L+ TGS ++ A ++K +E G I+ D Sbjct: 208 GDVGAALVNHRLTAKVSLTGSVPTGRRIMAQAGEQLKHVTMELGGKSPLIVFDDADLESA 267 Query: 424 ISWVCDQDAYACSGQKCSAQSMLFMHKNWSS---SGLLEKMKKLSERRKLEDLT-IGPVL 591 I + Y+ +GQ CS + +F+HKN L+E+ +K+ ++ T +GP++ Sbjct: 268 IGGAMLGNFYS-TGQVCSNGTRVFVHKNIRERFIERLVERTRKIRIGDPFDEATQMGPLI 326 Query: 592 T 594 + Sbjct: 327 S 327
>GABD_SYNY3 (Q55585) Probable succinate-semialdehyde dehydrogenase [NADP+] (EC| 1.2.1.16) (SSDH) Length = 454 Score = 37.4 bits (85), Expect = 0.039 Identities = 44/189 (23%), Positives = 71/189 (37%), Gaps = 8/189 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G + + P+NFP AL GN +LK S V + + G P Sbjct: 120 PLGVILAVMPWNFPFWQVFRFAAPALMAGNVGLLKHASNVPQCALAIAEIFQTAGFPEGA 179 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAGFDWKILGP 402 + G ++L+ + + TGS A+ G+IK LE G D I+ Sbjct: 180 FQTLLIGGKVASELMADDRIQAGTLTGSEPAGASFASAAAGQIKKTVLELGGSDPFIVLE 239 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKLED---- 570 D ++D V +GQ C A + + + +++ K + K+ D Sbjct: 240 DA-DLDQALKVAVPARMQNNGQSCIAAKRFIVQASVAEE-FFQRLTKAFQALKVGDPSLS 297 Query: 571 -LTIGPVLT 594 IGP+ T Sbjct: 298 TTDIGPLAT 306
>CROM_OMMSL (P30842) Omega-crystallin| Length = 494 Score = 37.0 bits (84), Expect = 0.050 Identities = 37/174 (21%), Positives = 70/174 (40%), Gaps = 5/174 (2%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G ++ P+N+P+ + ++ AL GN ++K + + L+ E G P Sbjct: 152 PVGVCGLLIPYNYPMLMMTWKMAPALACGNCMIVKPAEQTPLTALYCASLIKEAGFPPGV 211 Query: 232 VDFINSDG-ITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDV 408 V+ + G I + FTGS+ V + D G+ L+ P V Sbjct: 212 VNVVPGFGKICGQYISSHQEINKVSFTGSTEVGMLVMQD-AGKSNLKRCSMQLSGKCPLV 270 Query: 409 ----QEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 E+D+ + A+ GQ + S ++H+N + ++K + R+ Sbjct: 271 VFEDTELDFAVQQAHEAAFQNMGQCRWSGSRTYVHENIYDEFVKRAVEKATSRK 324
>ALDH_ALTAL (P42041) Aldehyde dehydrogenase (EC 1.2.1.3) (ALDDH) (Allergen Alt| a 10) (Alt a X) Length = 495 Score = 37.0 bits (84), Expect = 0.050 Identities = 40/174 (22%), Positives = 71/174 (40%), Gaps = 9/174 (5%) Frame = +1 Query: 10 EGKXVGQMSNGYRWPFGPVAIITPFNFPLEIPLL----QLMGALYMGNKPVLKVDSKVSI 177 EGK V + + + ++ +E+P+L ++ A+ GN VLK + + Sbjct: 136 EGKVVDTAPDSFNY-IRKSLLVFAVRSSMELPILMWSWKIGPAIATGNTVVLKTAEQTPL 194 Query: 178 VMEQMIRLLHECGLPAEDVDFINSDG-ITMNKLLLEANPKMTLFTGSSRVAEKLAADLQG 354 +L+ E G P ++ I G I + + FTGS+ V ++ G Sbjct: 195 SAYIACKLIQEAGFPPGVINVITGFGKIAGAAMSAHMDIDKIAFTGSTVVGRQIMKSAAG 254 Query: 355 ----RIKLEDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 ++ LE G I+ D + I WV + Y GQ C A S +++ + Sbjct: 255 SNLKKVTLELGGKSPNIVFADADLDEAIHWV-NFGIYFNHGQACCAGSRIYVQE 307
>AL7A1_BRANA (Q41247) Aldehyde dehydrogenase family 7 member A1 (EC 1.2.1.3)| (Antiquitin-1) (Brassica turgor-responsive/drought-induced gene 26 protein) (Btg-26) Length = 493 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 7/159 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLK---VDSKVSIVMEQMI-RLLHECGL 219 P G V +IT FNFP + AL GN V K ++I M +++ +L + L Sbjct: 156 PLGIVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKLVAEVLEKNHL 215 Query: 220 PAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRV---AEKLAADLQGRIKLEDAGFDWK 390 P + + + + FTGSS+V ++ + G+ LE +G + Sbjct: 216 PGAIFTAMCGGAEIGEAIAKDTRIPLVSFTGSSKVGLTVQQTVSARSGKTLLELSGNN-A 274 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 I+ D ++ + A +GQ+C+ L +H++ Sbjct: 275 IIVMDDADIQLAARSVLFAAVGTAGQRCTTCRRLLLHES 313
>ALDB_ECOLI (P37685) Aldehyde dehydrogenase B (EC 1.2.1.-)| Length = 512 Score = 35.8 bits (81), Expect = 0.11 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFPL + ++ AL GN VLK + + ++ ++ + LP Sbjct: 160 PLGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDL-LPPGV 218 Query: 232 VDFINSDGITMNKLLLEANP-KMTLFTGSSRVAEKL 336 V+ +N G + + L + FTGS+ V +++ Sbjct: 219 VNVVNGAGGVIGEYLATSKRIAKVAFTGSTEVGQQI 254
>ALDA_STAAW (Q7A1Y7) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 495 Score = 35.8 bits (81), Expect = 0.11 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + ++ A+ GN V++ S + + ++ ++ E LP Sbjct: 148 PIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEV-LPKGV 206 Query: 232 VDFINSDGITMNKLLLEANPKMTL-FTGSS----RVAEKLAADL----------QGRIKL 366 V+ + G + + L FTGS+ +VAE A L I L Sbjct: 207 VNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIIL 266 Query: 367 EDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 +DA D + G + G+ CSA S L +H+ Sbjct: 267 DDANLDLAVEGIQL------------GILFNQGEVCSAGSRLLVHE 300
>ALDA_STAAS (Q6GCV9) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 495 Score = 35.8 bits (81), Expect = 0.11 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + ++ A+ GN V++ S + + ++ ++ E LP Sbjct: 148 PIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEV-LPKGV 206 Query: 232 VDFINSDGITMNKLLLEANPKMTL-FTGSS----RVAEKLAADL----------QGRIKL 366 V+ + G + + L FTGS+ +VAE A L I L Sbjct: 207 VNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIIL 266 Query: 367 EDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 +DA D + G + G+ CSA S L +H+ Sbjct: 267 DDANLDLAVEGIQL------------GILFNQGEVCSAGSRLLVHE 300
>ALDA_STAAN (Q7A825) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 495 Score = 35.8 bits (81), Expect = 0.11 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + ++ A+ GN V++ S + + ++ ++ E LP Sbjct: 148 PIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEV-LPKGV 206 Query: 232 VDFINSDGITMNKLLLEANPKMTL-FTGSS----RVAEKLAADL----------QGRIKL 366 V+ + G + + L FTGS+ +VAE A L I L Sbjct: 207 VNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIIL 266 Query: 367 EDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 +DA D + G + G+ CSA S L +H+ Sbjct: 267 DDANLDLAVEGIQL------------GILFNQGEVCSAGSRLLVHE 300
>ALDA_STAAM (Q99X54) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 495 Score = 35.8 bits (81), Expect = 0.11 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + ++ A+ GN V++ S + + ++ ++ E LP Sbjct: 148 PIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEV-LPKGV 206 Query: 232 VDFINSDGITMNKLLLEANPKMTL-FTGSS----RVAEKLAADL----------QGRIKL 366 V+ + G + + L FTGS+ +VAE A L I L Sbjct: 207 VNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIIL 266 Query: 367 EDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 +DA D + G + G+ CSA S L +H+ Sbjct: 267 DDANLDLAVEGIQL------------GILFNQGEVCSAGSRLLVHE 300
>ALDA_STAAC (Q5HJK3) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 495 Score = 35.8 bits (81), Expect = 0.11 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + ++ A+ GN V++ S + + ++ ++ E LP Sbjct: 148 PIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEV-LPKGV 206 Query: 232 VDFINSDGITMNKLLLEANPKMTL-FTGSS----RVAEKLAADL----------QGRIKL 366 V+ + G + + L FTGS+ +VAE A L I L Sbjct: 207 VNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIIL 266 Query: 367 EDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 +DA D + G + G+ CSA S L +H+ Sbjct: 267 DDANLDLAVEGIQL------------GILFNQGEVCSAGSRLLVHE 300
>FTHFD_HUMAN (O75891) 10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6)| (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1) Length = 902 Score = 35.4 bits (80), Expect = 0.15 Identities = 41/187 (21%), Positives = 78/187 (41%), Gaps = 9/187 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II P+N+PL + + L GN V+K + + L + G+P Sbjct: 563 PVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGV 622 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSSRVAEKL----AADLQGRIKLEDAGFDWKIL 396 V+ + G + + L + + + FTGS+ V + + A ++ LE G I+ Sbjct: 623 VNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLII 682 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSS---GLLEKMKKLSERRKLE 567 D +++ + + G+ C A LF+ + ++E+++K+ L+ Sbjct: 683 FADC-DLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLD 741 Query: 568 -DLTIGP 585 D GP Sbjct: 742 RDTDHGP 748
>ALDH_RHORT (Q9ZA11) Aldehyde dehydrogenase (EC 1.2.1.3)| Length = 506 Score = 35.4 bits (80), Expect = 0.15 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 4/127 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFP+ + +L AL GN VLK + I + + L+ + LP Sbjct: 154 PLGVVGQIIPWNFPILMATWKLAPALAAGNCIVLKPAEQTPISILVLTELIADL-LPPGV 212 Query: 232 VDFINSDGITMNKLLLE----ANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILG 399 ++ +N G+ K L A T T + R+ + A+ + LE G + Sbjct: 213 LNVVNGFGLEAGKPLASSKRIAKIAFTGETATGRLIMQYASQNLIPVTLELGGKSPNVFF 272 Query: 400 PDVQEVD 420 D+ D Sbjct: 273 DDIASAD 279
>AL3A2_HUMAN (P51648) Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde| dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10) Length = 485 Score = 35.4 bits (80), Expect = 0.15 Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 14/157 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V II +N+P + + L+GA+ GN ++K + + +LL + +D Sbjct: 101 PLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQ--YLDQD 158 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDVQ 411 + + + G+ LL+ +TG++ V G+I +E A K L P Sbjct: 159 LYIVINGGVEETTELLKQRFDHIFYTGNTAV---------GKIVMEAAA---KHLTPVTL 206 Query: 412 EVD-----YISWVCDQD---------AYACSGQKCSA 480 E+ YI CD D Y GQ C A Sbjct: 207 ELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIA 243
>ALDA_STAAR (Q6GKD8) Putative aldehyde dehydrogenase aldA (EC 1.2.1.3)| Length = 495 Score = 35.4 bits (80), Expect = 0.15 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V + +NFP+ + ++ A+ GN V++ S + + ++ ++ E LP Sbjct: 148 PIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEV-LPNGV 206 Query: 232 VDFINSDGITMNKLLLEANPKMTL-FTGSS----RVAEKLAADL----------QGRIKL 366 V+ + G + + L FTGS+ +VAE A L I L Sbjct: 207 VNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIIL 266 Query: 367 EDAGFDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHK 504 +DA D + G + G+ CSA S L +H+ Sbjct: 267 DDANLDLAVEGIQL------------GILFNQGEVCSAGSRLLVHE 300
>FTHFD_PONPY (Q5RFM9) 10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6)| (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1) Length = 902 Score = 35.0 bits (79), Expect = 0.19 Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 5/154 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G II P+N+PL + + L GN V+K + + L + G+P Sbjct: 563 PVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGV 622 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSSRVAEKL----AADLQGRIKLEDAGFDWKIL 396 V+ + G + + L + + + FTGS+ V + + A ++ LE G I+ Sbjct: 623 VNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLII 682 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM 498 D +++ + + G+ C A LF+ Sbjct: 683 FADC-DLNKAVQMGMSSVFFNKGENCIAAGRLFV 715
>FTHFD_MOUSE (Q8R0Y6) 10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6)| (10-FTHFDH) (Aldehyde dehydrogenase 1 family member L1) Length = 902 Score = 35.0 bits (79), Expect = 0.19 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 5/154 (3%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I+ P+N+PL + + L GN V+K + + L + G+P Sbjct: 563 PVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGV 622 Query: 232 VDFINSDGITMNKLLLE-ANPKMTLFTGSSRVAEKL----AADLQGRIKLEDAGFDWKIL 396 V+ + G + + L + + + FTGS+ V + + A ++ LE G I+ Sbjct: 623 VNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLII 682 Query: 397 GPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM 498 D +++ + + G+ C A LF+ Sbjct: 683 FADC-DLNKAVQMGMSSVFFNKGENCIAAGRLFV 715
>CALB_PSEUH (O86447) Coniferyl aldehyde dehydrogenase (EC 1.2.1.68) (CALDH)| Length = 480 Score = 35.0 bits (79), Expect = 0.19 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 7/156 (4%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLK---VDSKVSIVMEQMIRLLHECGLP 222 P G V +I+P+NFP+ + L G GN+ +LK + + S ++ ++I Sbjct: 114 PLGVVGVISPWNFPIVLAFGPLAGIFAAGNRAMLKPSELTPRTSALLAELIARYF----- 168 Query: 223 AEDVDFINSDGITMNKLLLEANP-KMTLFTGSSRVAE---KLAADLQGRIKLEDAGFDWK 390 ++ + G L A P +FTG + VA+ + AAD + LE G Sbjct: 169 -DETELTTVLGDAEVGALFSAQPFDHLIFTGGTAVAKHIMRAAADNLVPVTLELGGKSPV 227 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFM 498 I+ D V + +GQ C A + + Sbjct: 228 IVSRSADMADVAQRVLTVKTFN-AGQICLAPDYVLL 262
>ALDH_MYCTU (P63937) Probable aldehyde dehydrogenase (EC 1.2.1.3)| Length = 507 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFP+ + +L AL GN VLK + + ++ L+ + LP Sbjct: 155 PLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDL-LPPGV 213 Query: 232 VDFINSDGITMNKLLLEANP-KMTLFTGSS 318 V+ +N G K L ++ FTG + Sbjct: 214 VNVVNGFGAEAGKPLASSDRIAKVAFTGET 243
>ALDH_MYCBO (P63938) Probable aldehyde dehydrogenase (EC 1.2.1.3)| Length = 507 Score = 35.0 bits (79), Expect = 0.19 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V I P+NFP+ + +L AL GN VLK + + ++ L+ + LP Sbjct: 155 PLGVVGQIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDL-LPPGV 213 Query: 232 VDFINSDGITMNKLLLEANP-KMTLFTGSS 318 V+ +N G K L ++ FTG + Sbjct: 214 VNVVNGFGAEAGKPLASSDRIAKVAFTGET 243
>PYREL_METJA (Q59040) PyrE-like protein| Length = 211 Score = 34.7 bits (78), Expect = 0.25 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%) Frame = +1 Query: 241 INSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLE--DAGFDWKILGPDVQE 414 + S+G+T+ ++ E N M AEKL + + IKLE D DWK +G Sbjct: 16 LKSNGLTIGEIAEELNVSMETARYLVLNAEKLLKEEEKAIKLENVDIFIDWKNIGSSANR 75 Query: 415 VDYIS 429 + YIS Sbjct: 76 LKYIS 80
>SSDH_MOUSE (Q8BWF0) Succinate semialdehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 523 Score = 34.3 bits (77), Expect = 0.33 Identities = 46/205 (22%), Positives = 79/205 (38%), Gaps = 12/205 (5%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G AIITP+NFP + ++ AL G V+K + +L ++ G+PA Sbjct: 182 PVGVAAIITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPYSALALAQLANQAGIPAGV 241 Query: 232 VDFI----NSDGITMNKLLLEANPKMTLFTGSSRVAEKL---AADLQGRIKLEDAGFDWK 390 + I N L + FTGS+ + L AA+ R+ +E G Sbjct: 242 YNVIPCSRNKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAPF 301 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL-- 564 I+ D VD + +GQ C + + + S + + + + + ++ Sbjct: 302 IVF-DSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGN 360 Query: 565 ---EDLTIGPVLTVTTSTMIEHMNN 630 E T GP++ +E N Sbjct: 361 GFEEGTTQGPLINEKAVEKVEKQVN 385
>AL3A2_MACFA (Q60HH8) Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde| dehydrogenase, microsomal) (Aldehyde dehydrogenase family 3 member A2) (Aldehyde dehydrogenase 10) Length = 485 Score = 34.3 bits (77), Expect = 0.33 Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 14/169 (8%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G V II +N+P + + L+GA+ GN ++K + + +LL + +D Sbjct: 101 PLGVVLIIGAWNYPFVLIIQPLIGAIAAGNAVIIKPSELSENTAKIVAKLLPQ--YLDQD 158 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIKLEDAGFDWKILGPDVQ 411 + + + G+ LL+ +TG++ V G+I +E A K L P Sbjct: 159 LYVVINGGVEETTELLKQRFDHIFYTGNTAV---------GKIVMEAAA---KHLTPVTL 206 Query: 412 EVD-----YISWVCDQD---------AYACSGQKCSAQSMLFMHKNWSS 516 E+ YI CD D Y GQ C A + + S Sbjct: 207 ELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQS 255
>AL9A1_HUMAN (P49189) 4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47)| (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3) (Aldehyde dehydrogenase E3 isozyme) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogen Length = 494 Score = 33.9 bits (76), Expect = 0.43 Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 10/196 (5%) Frame = +1 Query: 34 SNGY--RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLH 207 S GY R P G I +N+P +I + AL GN V K + + + Sbjct: 138 SFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYS 197 Query: 208 ECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAG 378 E G+P + + T L + FTGS K+ IK LE G Sbjct: 198 EAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGG 257 Query: 379 FDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 I+ D + + + + GQ C + +F+ K E++ K ++R Sbjct: 258 KSPLIIFSDCDMNNAVKGALMAN-FLTQGQVCCNGTRVFVQKEILDK-FTEEVVKQTQRI 315 Query: 559 K-----LEDLTIGPVL 591 K LED +GP++ Sbjct: 316 KIGDPLLEDTRMGPLI 331
>AL9A1_PONPY (Q5R8A4) 4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47)| (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3) Length = 494 Score = 33.5 bits (75), Expect = 0.56 Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 10/196 (5%) Frame = +1 Query: 34 SNGY--RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLH 207 S GY R P G I +N+P +I + AL GN V K + + + Sbjct: 138 SFGYTRREPLGVCVGIGAWNYPFQITSWKSAPALACGNAMVFKPSPFTPVSALLLAEIYT 197 Query: 208 ECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEKLAADLQGRIK---LEDAG 378 E G+P + + T L + FTGS K+ IK LE G Sbjct: 198 EAGVPPGLFNVVQGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGG 257 Query: 379 FDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 I+ D + + + + GQ C + +F+ K E++ K ++R Sbjct: 258 KSPLIIFSDCDMNNAVKGALMAN-FLTQGQVCCNGTRVFVQKEILDK-FTEEVVKQTQRI 315 Query: 559 K-----LEDLTIGPVL 591 K LED +GP++ Sbjct: 316 KIGDPLLEDTRMGPLI 331
>ALDH3_BACSU (P46329) Probable aldehyde dehydrogenase aldX (EC 1.2.1.3)| Length = 445 Score = 33.1 bits (74), Expect = 0.73 Identities = 34/155 (21%), Positives = 61/155 (39%), Gaps = 3/155 (1%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G I+ P+N+P + + L +L GN ++K+ +++ + E Sbjct: 108 PKGVTLILGPWNYPFMLTMAPLAASLAAGNSAIVKLSDFTMNTSNIAAKVIRDAFNEKEV 167 Query: 232 VDFINSDGITMNKLLLEANPKMTLFTGSSRVAE---KLAADLQGRIKLEDAGFDWKILGP 402 F + + LL+ FTGS+ V + AA + LE G I+ Sbjct: 168 AIF--EGEVEVATELLDQPFDHIFFTGSTNVGKIVMTAAAKHLASVTLELGGKSPTIIDS 225 Query: 403 DVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKN 507 + +D + + +GQ C A LF+ K+ Sbjct: 226 EYDLMDAAKKIA-VGKFVNAGQTCIAPDYLFIKKD 259
>CALB_CAUCR (Q9A777) Probable coniferyl aldehyde dehydrogenase (EC 1.2.1.68)| (CALDH) Length = 485 Score = 33.1 bits (74), Expect = 0.73 Identities = 13/35 (37%), Positives = 21/35 (60%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLK 156 P G V +I+P+NFP+ + L G GN+ ++K Sbjct: 120 PKGVVGVISPWNFPVNLTFAPLAGVFAAGNRAMIK 154
>SSDH_RAT (P51650) Succinate semialdehyde dehydrogenase (EC 1.2.1.24)| (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 488 Score = 32.7 bits (73), Expect = 0.95 Identities = 45/206 (21%), Positives = 86/206 (41%), Gaps = 13/206 (6%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPAED 231 P G +IITP+NFP + ++ AL G V+K + +L ++ G+P Sbjct: 147 PVGVASIITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPYSALALAQLANQAGIPPGV 206 Query: 232 VDFINSDGITMNKL--LLEANPKMT--LFTGSSRVAEKL---AADLQGRIKLEDAGFDWK 390 + I ++ +L +P ++ FTGS+ + L AA+ R+ +E G Sbjct: 207 YNVIPCSRTKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAPF 266 Query: 391 ILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERRKL-- 564 I+ D VD + +GQ C + + + S + + + + + ++ Sbjct: 267 IVF-DSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGN 325 Query: 565 ---EDLTIGPVLTVTTSTMIE-HMNN 630 E T GP++ +E H+N+ Sbjct: 326 GFEEGTTQGPLINEKAVEKVEKHVND 351
>LEU2_RHINI (P55811) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 750 Score = 32.7 bits (73), Expect = 0.95 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 5/79 (6%) Frame = -1 Query: 440 SQTHEI*STS*TSGPRIFQSKPASSNLIRPCKSAASFSATRELPVKRVIFGFA-----SN 276 S E+ ++ P +F+S ++ ++P + A+ S++ +P + G+A SN Sbjct: 483 SPRQEVVASKYDGSPEVFKSTQDTTPAVKPPQPASDSSSSGGMPAFTTLKGYAAPLDISN 542 Query: 275 SSLFIVIPSEFMKSTSSAG 219 ++IP +F+K+ G Sbjct: 543 IDTDMIIPKQFLKTIKRTG 561
>AL9A1_MOUSE (Q9JLJ2) 4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47)| (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3) Length = 494 Score = 31.2 bits (69), Expect = 2.8 Identities = 43/195 (22%), Positives = 73/195 (37%), Gaps = 9/195 (4%) Frame = +1 Query: 34 SNGY--RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLH 207 S GY R P G I +N+P +I + AL GN + K + + + Sbjct: 138 SFGYTRREPLGVCVGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYT 197 Query: 208 ECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEK---LAADLQGRIKLEDAG 378 + G P + + T L FTGS K ++A I LE G Sbjct: 198 KAGAPPGLFNVVQGGAATGQFLCHHREVAKISFTGSVPTGVKIMEMSAKGVKPITLELGG 257 Query: 379 FDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 I+ D + + + + GQ C + +F+ K + + E +K+ + + Sbjct: 258 KSPLIIFSDCNMENAVKGALMAN-FLTQGQVCCNGTRVFVQKEIADKFINEVVKQTQKIK 316 Query: 559 ----KLEDLTIGPVL 591 LED +GP++ Sbjct: 317 LGDPLLEDTRMGPLI 331
>SSDH_PONPY (Q6A2H2) Succinate semialdehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 535 Score = 30.8 bits (68), Expect = 3.6 Identities = 17/58 (29%), Positives = 27/58 (46%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 P G A+ITP+NFP + ++ AL G V+K + L + G+P+ Sbjct: 194 PIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPS 251
>SSDH_PANPA (Q3MSM4) Succinate semialdehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 535 Score = 30.8 bits (68), Expect = 3.6 Identities = 17/58 (29%), Positives = 27/58 (46%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 P G A+ITP+NFP + ++ AL G V+K + L + G+P+ Sbjct: 194 PIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPS 251
>SSDH_HYLLA (Q3MSM3) Succinate semialdehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 535 Score = 30.8 bits (68), Expect = 3.6 Identities = 17/58 (29%), Positives = 27/58 (46%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 P G A+ITP+NFP + ++ AL G V+K + L + G+P+ Sbjct: 194 PIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPS 251
>SSDH_HUMAN (P51649) Succinate semialdehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 535 Score = 30.8 bits (68), Expect = 3.6 Identities = 17/58 (29%), Positives = 27/58 (46%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 P G A+ITP+NFP + ++ AL G V+K + L + G+P+ Sbjct: 194 PIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPS 251
>SSDH_GORGO (Q6A2H1) Succinate semialdehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 535 Score = 30.8 bits (68), Expect = 3.6 Identities = 17/58 (29%), Positives = 27/58 (46%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 P G A+ITP+NFP + ++ AL G V+K + L + G+P+ Sbjct: 194 PIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPS 251
>SSDH_PANTR (Q6A2H0) Succinate semialdehyde dehydrogenase, mitochondrial| precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Length = 535 Score = 30.4 bits (67), Expect = 4.7 Identities = 17/58 (29%), Positives = 27/58 (46%) Frame = +1 Query: 52 PFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHECGLPA 225 P G A+ITP+NFP + ++ AL G V+K + L + G+P+ Sbjct: 194 PXGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPS 251
>AL9A1_RAT (Q9JLJ3) 4-trimethylaminobutyraldehyde dehydrogenase (EC 1.2.1.47)| (TMABADH) (Aldehyde dehydrogenase 9A1) (EC 1.2.1.3) Length = 494 Score = 30.4 bits (67), Expect = 4.7 Identities = 45/196 (22%), Positives = 76/196 (38%), Gaps = 10/196 (5%) Frame = +1 Query: 34 SNGY--RWPFGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLH 207 S GY R P G I +N+P +I + AL GN + K + + + Sbjct: 138 SFGYTRREPLGVCLGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYT 197 Query: 208 ECGLPAEDVDFINSDGITMNKLLLEANPKMTLFTGSSRVAEK---LAADLQGRIKLEDAG 378 + G P + + T L + FTGS K +AA I LE G Sbjct: 198 KAGAPNGLFNVVQGGAATGQFLCQHRDVAKVSFTGSVPTGMKIMEMAAKGIKPITLELGG 257 Query: 379 FDWKILGPDVQEVDYISWVCDQDAYACSGQKCSAQSMLFMHKNWSSSGLLEKMKKLSERR 558 I+ D + + + + GQ C + +F+ K + + E +++ ++R Sbjct: 258 KSPLIIFSDCNMKNAVKGALLAN-FLTQGQVCCNGTRVFVQKEIADAFTKEVVRQ-TQRI 315 Query: 559 K-----LEDLTIGPVL 591 K LED +GP++ Sbjct: 316 KIGDPLLEDTRMGPLI 331 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 95,233,876 Number of Sequences: 219361 Number of extensions: 2000362 Number of successful extensions: 5351 Number of sequences better than 10.0: 211 Number of HSP's better than 10.0 without gapping: 5129 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5294 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6086476506 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
