ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name bags17l09
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-... 314 1e-85
2UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-... 313 3e-85
3TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protei... 233 2e-61
4PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-... 226 5e-59
5HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein... 217 2e-56
6HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1... 217 2e-56
7HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein... 217 2e-56
8TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (E... 201 9e-52
9PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-) 201 9e-52
10PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-) 198 1e-50
11RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-) 190 2e-48
12TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-... 189 4e-48
13SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC... 174 1e-43
14PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-) 173 3e-43
15SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC... 172 5e-43
16NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.... 172 5e-43
17NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like prot... 171 1e-42
18NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like prot... 171 1e-42
19NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like prot... 171 1e-42
20SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC... 171 1e-42
21ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (E... 171 1e-42
22SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC... 171 1e-42
23ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-) 171 1e-42
24WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 ... 170 3e-42
25SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of de... 169 5e-42
26WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 ... 168 1e-41
27NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) 167 2e-41
28NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2... 167 2e-41
29NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) 166 4e-41
30WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 ... 164 2e-40
31WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 ... 164 2e-40
32SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.... 155 1e-37
33K0317_MOUSE (Q8CHG5) Protein KIAA0317 130 2e-30
34K0317_HUMAN (O15033) Protein KIAA0317 130 3e-30
35UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-) 121 2e-27
36HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6... 120 2e-27
37UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-) 119 5e-27
38UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (... 115 7e-26
39UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (... 113 4e-25
40HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6... 109 5e-24
41HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3 109 6e-24
42HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6... 107 2e-23
43UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB f... 98 2e-20
44HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing... 97 3e-20
45HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing... 97 4e-20
46HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT do... 95 1e-19
47HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (P... 90 5e-18
48EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hy... 89 7e-18
49EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (... 89 7e-18
50EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (... 89 7e-18
51YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protei... 89 9e-18
52HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing... 89 9e-18
53TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TR... 87 3e-17
54HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing... 83 5e-16
55MUT7_CAEEL (P34607) Probable exonuclease mut-7 (EC 3.1.-.-) 30 3.6
56PLSB_PASMU (Q9CLN7) Glycerol-3-phosphate acyltransferase (EC 2.3... 30 3.6
57A85B_MYCSC (Q50397) Antigen 85-B precursor (85B) (Extracellular ... 30 4.8
58A85B_MYCIT (Q49575) Antigen 85-B precursor (85B) (Extracellular ... 30 4.8
59A85B_MYCAV (Q06947) Antigen 85-B precursor (85B) (Extracellular ... 30 4.8
60A85B_MYCTU (P31952) Antigen 85-B precursor (85B) (Extracellular ... 30 4.8
61A85B_MYCKA (P21160) Antigen 85-B precursor (85B) (Extracellular ... 30 4.8
62A85B_MYCBO (P12942) Antigen 85-B precursor (85B) (Extracellular ... 30 4.8
63PAM1_YEAST (P37304) Protein PAM1 30 4.8
64CENB2_HUMAN (Q15057) Centaurin-beta 2 (Cnt-b2) 30 6.2
65TALA_DICDI (P54633) Filopodin (Talin homolog) 30 6.2
66PK1_NPVLD (P41720) Serine/threonine-protein kinase 1 (EC 2.7.11.1) 29 8.1
67OBSCN_HUMAN (Q5VST9) Obscurin (Obscurin-myosin light chain kinas... 29 8.1
68IDI2_METMP (Q6M174) Isopentenyl-diphosphate delta-isomerase (EC ... 29 8.1
69ADR1_YEAST (P07248) Regulatory protein ADR1 29 8.1 
>UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 2)
          Length = 3658

 Score =  314 bits (805), Expect = 1e-85
 Identities = 152/185 (82%), Positives = 165/185 (89%)
 Frame = +3

Query: 12   EEKLILYEKAEVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNE 191
            EEK ILYEK EVTD EL PGGRNIRVTEE KHEYVD VA+H LT+AIRPQINAF+EG NE
Sbjct: 3457 EEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVADHILTSAIRPQINAFLEGLNE 3516

Query: 192  LIPRELISIFNDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKED 371
            LIPREL+SIFNDKE ELLISGLP+ID DDLKANTEY+ Y++ SPVI+WFWE+V+ FSKED
Sbjct: 3517 LIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTVGSPVIRWFWEVVKAFSKED 3576

Query: 372  KARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTS 551
             ARFLQFVTGTSKVPLEGF ALQGISGPQR QIHKAYGS   LPSAHTCFNQLDLPEY S
Sbjct: 3577 MARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGSPERLPSAHTCFNQLDLPEYQS 3636

Query: 552  KDQLQ 566
            K+Q+Q
Sbjct: 3637 KEQVQ 3641
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>UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 1)
          Length = 3684

 Score =  313 bits (801), Expect = 3e-85
 Identities = 153/185 (82%), Positives = 162/185 (87%)
 Frame = +3

Query: 12   EEKLILYEKAEVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNE 191
            EEK ILYEK EVTD EL PGGRNIRVTEE KHEYVD VA H LT AIRPQINAF+EGFNE
Sbjct: 3480 EEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTNAIRPQINAFLEGFNE 3539

Query: 192  LIPRELISIFNDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKED 371
            LIPREL+SIFNDKE ELLISGLP+ID DDLKANTEY+ Y+  SPVI WFWE+V+ FSKED
Sbjct: 3540 LIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTAGSPVIHWFWEVVKAFSKED 3599

Query: 372  KARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTS 551
             ARFLQFVTGTSKVPLEGF ALQGISGPQR QIHKAYG+   LPSAHTCFNQLDLPEY S
Sbjct: 3600 MARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGAPERLPSAHTCFNQLDLPEYQS 3659

Query: 552  KDQLQ 566
            K+QLQ
Sbjct: 3660 KEQLQ 3664
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>TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protein (EC 6.3.2.-)|
          Length = 4065

 Score =  233 bits (595), Expect = 2e-61
 Identities = 109/175 (62%), Positives = 136/175 (77%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            EV   +LI  GRNI VTEENKHEYV  + EH+L T+++ Q+ AF+ GF+E+IP ELI+IF
Sbjct: 3874 EVKVVDLIENGRNIPVTEENKHEYVRLIVEHKLITSVKDQMKAFLTGFHEIIPEELIAIF 3933

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            N++E ELLISGLPDID+DD KANTEY  YS  +P IQWFW  V+ F KE+ A+ LQFVTG
Sbjct: 3934 NEQELELLISGLPDIDIDDWKANTEYHNYSAGAPQIQWFWRAVRSFDKEELAKLLQFVTG 3993

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            TSKVPL GF  L+G++G  RF IH+ YGS + LPS+HTCFNQLDLPEY + + L+
Sbjct: 3994 TSKVPLNGFKELEGMNGVSRFNIHRDYGSKDRLPSSHTCFNQLDLPEYENYETLR 4048
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>PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-) (Poly(A)+ RNA|
            transport protein 1)
          Length = 3227

 Score =  226 bits (575), Expect = 5e-59
 Identities = 101/175 (57%), Positives = 137/175 (78%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            E T  +LIP GRNI VTE NK  YV+R+ +++L  +++ Q+ + ++GF+++IP  LI IF
Sbjct: 3036 EKTVVDLIPNGRNIPVTELNKQNYVNRMVDYKLRESVKDQLKSLLDGFSDIIPSHLIQIF 3095

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            N++E ELLISGLP+ID+DD K NTEY GY+++SP +QWFW  V+ F +E++A+ LQF TG
Sbjct: 3096 NEQELELLISGLPEIDIDDWKNNTEYHGYNVSSPQVQWFWRAVRSFDEEERAKLLQFATG 3155

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            TSKVPL GF  L+G+SG QRF IHK+YGS N LP +HTCFNQLDLPEY + +QL+
Sbjct: 3156 TSKVPLNGFKELEGMSGFQRFNIHKSYGSLNRLPQSHTCFNQLDLPEYDTYEQLR 3210
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>HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (E3Histone)
          Length = 4377

 Score =  217 bits (553), Expect = 2e-56
 Identities = 106/170 (62%), Positives = 133/170 (78%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            +L P G NI VTEENK EYV  V + R+T AIR Q+ AF+EGF E+IP+ LISIF ++E 
Sbjct: 4191 DLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQEL 4250

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            ELLISGLP ID+DDLK+NTEY  Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVP
Sbjct: 4251 ELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4310

Query: 417  LEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            L+GF+AL+G++G Q+FQIH+   ST+ LPSAHTCFNQLDLP Y S ++L+
Sbjct: 4311 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLR 4360
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>HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
           (E3 ubiquitin protein ligase URE-B1) (Upstream
           regulatory element-binding protein 1) (Fragment)
          Length = 322

 Score =  217 bits (553), Expect = 2e-56
 Identities = 106/170 (62%), Positives = 133/170 (78%)
 Frame = +3

Query: 57  ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
           +L P G NI VTEENK EYV  V + R+T AIR Q+ AF+EGF E+IP+ LISIF ++E 
Sbjct: 136 DLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQEL 195

Query: 237 ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
           ELLISGLP ID+DDLK+NTEY  Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVP
Sbjct: 196 ELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 255

Query: 417 LEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
           L+GF+AL+G++G Q+FQIH+   ST+ LPSAHTCFNQLDLP Y S ++L+
Sbjct: 256 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLR 305
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>HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin
            ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1)
          Length = 4374

 Score =  217 bits (553), Expect = 2e-56
 Identities = 106/170 (62%), Positives = 133/170 (78%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            +L P G NI VTEENK EYV  V + R+T AIR Q+ AF+EGF E+IP+ LISIF ++E 
Sbjct: 4188 DLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQEL 4247

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            ELLISGLP ID+DDLK+NTEY  Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVP
Sbjct: 4248 ELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVP 4307

Query: 417  LEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            L+GF+AL+G++G Q+FQIH+   ST+ LPSAHTCFNQLDLP Y S ++L+
Sbjct: 4308 LQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLR 4357
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>TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
          Length = 3258

 Score =  201 bits (512), Expect = 9e-52
 Identities = 91/170 (53%), Positives = 127/170 (74%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            ELI  G ++ VTE+NKH+YV ++ E++L T+++ Q+  F++GF  +IP++LISIF+++E 
Sbjct: 3072 ELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQEL 3131

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            ELL+SGLPDID+DD K NT Y  Y+     I +FW  V+ F KE++A+ LQFVTGTSKVP
Sbjct: 3132 ELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVP 3191

Query: 417  LEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            L GF  L G++G  +F IH+ YGS + LPS+HTCFNQLDLP Y S + L+
Sbjct: 3192 LNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLR 3241
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>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)|
          Length = 767

 Score =  201 bits (512), Expect = 9e-52
 Identities = 97/174 (55%), Positives = 124/174 (71%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            EV   +L P GRNI VTEENK EYVD V   R+   I  Q NAF EGF+ELIP+ELI++F
Sbjct: 578  EVVTIDLKPNGRNIEVTEENKREYVDLVTVWRIQKRIEEQFNAFHEGFSELIPQELINVF 637

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            +++E ELLI G+ +ID++D K +T+Y  YS    +I+WFWE++  +S E K+R LQF TG
Sbjct: 638  DERELELLIGGISEIDMEDWKKHTDYRSYSENDQIIKWFWELMDEWSNEKKSRLLQFTTG 697

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            TS++P+ GF  LQG  GP++F I KA G  N LP AHTCFN+LDLP YTSK  L
Sbjct: 698  TSRIPVNGFKDLQGSDGPRKFTIEKA-GEPNKLPKAHTCFNRLDLPPYTSKKDL 750
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>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)|
          Length = 786

 Score =  198 bits (503), Expect = 1e-50
 Identities = 92/174 (52%), Positives = 125/174 (71%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            EV   ELI  G NI VTEENK +YVD V E R++  +  Q NAF  GF EL+  +L+++F
Sbjct: 597  EVRTVELITNGENIEVTEENKKKYVDLVTEWRVSKRVEQQFNAFYSGFVELVSPDLVNVF 656

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            +++E ELLI G+ D+D++D K++TEY  Y    PVI+WFWEI+ G+  ED+++ LQF TG
Sbjct: 657  DERELELLIGGISDVDVEDWKSHTEYRTYIATDPVIKWFWEIIAGWKNEDRSKLLQFATG 716

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            TS++P+ GF  LQG  GP++F I KA G+ + LP AHTCFN+LDLP+Y SKD L
Sbjct: 717  TSRIPVNGFRDLQGSDGPRKFTIEKA-GTPDQLPVAHTCFNRLDLPDYPSKDTL 769
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>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)|
          Length = 809

 Score =  190 bits (483), Expect = 2e-48
 Identities = 86/175 (49%), Positives = 121/175 (69%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            EV   +L P GRNI VT+ NK EYV+   + R+   ++ Q  AFM+GFNELIP +L+++F
Sbjct: 620  EVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNELIPEDLVTVF 679

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            +++E ELLI G+ +ID++D K +T+Y GY  +  VIQWFW+ V  +  E +AR LQF TG
Sbjct: 680  DERELELLIGGIAEIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTG 739

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            TS++P+ GF  LQG  GP+RF I KA G    LP +HTCFN++DLP+Y   D ++
Sbjct: 740  TSRIPVNGFKDLQGSDGPRRFTIEKA-GEVQQLPKSHTCFNRVDLPQYVDYDSMK 793
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>TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
            (Temperature-dependent organization in mitotic nucleus
            protein 1) (Suppressor of snRNA protein 2)
          Length = 3268

 Score =  189 bits (481), Expect = 4e-48
 Identities = 88/169 (52%), Positives = 124/169 (73%)
 Frame = +3

Query: 60   LIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEFE 239
            LI GG++I VTE NK +YV +V E++L T+++ Q++ F+ GF  LI ++LI+IF+++E E
Sbjct: 3083 LIEGGKDIIVTEANKQDYVKKVVEYKLQTSVKEQMDNFLVGFYALISKDLITIFDEQELE 3142

Query: 240  LLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPL 419
            LLISGLPDID+DD K NT Y  Y+     + +FW  V+ F  E++A+ LQFVTGTSKVPL
Sbjct: 3143 LLISGLPDIDVDDWKNNTTYVNYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPL 3202

Query: 420  EGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
             GF  L G++G  +F IH+ +GS+  LPS+HTCFNQL+LP Y S + L+
Sbjct: 3203 NGFKELSGVNGVCKFSIHRDFGSSERLPSSHTCFNQLNLPPYESYETLR 3251
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>SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)|
            (Ubiquitin--protein ligase SMURF2) (Smad-specific E3
            ubiquitin ligase 2) (hSMURF2)
          Length = 748

 Score =  174 bits (442), Expect = 1e-43
 Identities = 84/174 (48%), Positives = 116/174 (66%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            E+   EL P G++I V EENK EYV      R    I  Q  A  +GFNE+IP+ L+  F
Sbjct: 558  EIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTF 617

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            ++KE EL+I GL  ID++D K NT     +  S +++WFW+ V+ F +E +AR LQFVTG
Sbjct: 618  DEKELELIICGLGKIDVNDWKVNTRLKHCTPDSNIVKWFWKAVEFFDEERRARLLQFVTG 677

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            +S+VPL+GF ALQG +GP+ F IH+    TN+LP AHTCFN++D+P Y S ++L
Sbjct: 678  SSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYESYEKL 731
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>PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-)|
          Length = 671

 Score =  173 bits (438), Expect = 3e-43
 Identities = 80/175 (45%), Positives = 112/175 (64%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            E    +LIP GRNI V  +NK  Y+  + EH+L T+   Q NA   G NELIP  ++ IF
Sbjct: 482  ESVTVDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQFNALKGGLNELIPDSVLQIF 541

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            N+ E + L++G  DID+ D K  T+Y  Y+    ++ WFWE++  +S E KA+ LQF TG
Sbjct: 542  NENELDTLLNGKRDIDVQDWKRFTDYRSYTETDDIVIWFWELLSEWSPEKKAKLLQFATG 601

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            TS++PL GF  + G  GP++F I K  G  + LP AHTCFN+LD+P Y SK++L+
Sbjct: 602  TSRLPLSGFKDMHGSDGPRKFTIEKV-GHISQLPKAHTCFNRLDIPPYNSKEELE 655
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>SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
            (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
            ubiquitin ligase) (xSMURF1)
          Length = 731

 Score =  172 bits (437), Expect = 5e-43
 Identities = 85/172 (49%), Positives = 113/172 (65%), Gaps = 3/172 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL P G+N++VTEENK EYV      R    I  Q  A  +GFNELIP+ L+  F  KE 
Sbjct: 543  ELKPNGKNLQVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFEQKEL 602

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            EL+I GL  ID+ D KANT        S ++QWFW+ V+ F +E +AR LQFVTG+++VP
Sbjct: 603  ELIIGGLDKIDISDWKANTRLKHCLANSNIVQWFWQAVESFDEERRARLLQFVTGSTRVP 662

Query: 417  LEGFSALQ---GISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            L+GF ALQ   G +GP+ F IH    +T++LP AHTCFN++D+P Y S ++L
Sbjct: 663  LQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKL 714
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>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)|
          Length = 1007

 Score =  172 bits (437), Expect = 5e-43
 Identities = 86/171 (50%), Positives = 114/171 (66%), Gaps = 1/171 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL PGG NI VT ENK EY+  V E R    ++ Q+++F++GF  +IP  LI IF++ E 
Sbjct: 821  ELKPGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHEL 880

Query: 237  ELLISGLPDIDLDDLKANTEYSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ELL+ G+ +ID+ D + NT Y G Y +   +IQWFW  V  FS E ++R LQFVTGTS+V
Sbjct: 881  ELLMCGIQNIDVKDWRENTLYKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRV 940

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            P+ GF  L G +GPQ F I K +G+ N+ P AHTCFN+LDLP Y    QL+
Sbjct: 941  PMNGFKELYGSNGPQMFTIEK-WGTPNNFPRAHTCFNRLDLPPYEGYLQLK 990
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>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 975

 Score =  171 bits (433), Expect = 1e-42
 Identities = 85/171 (49%), Positives = 116/171 (67%), Gaps = 1/171 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            +L P G  I VT ENK EY+D V + R    ++ Q+NAF+EGF EL+P +LI IF++ E 
Sbjct: 789  DLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENEL 848

Query: 237  ELLISGLPDIDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ELL+ GL D+D++D + ++ Y +GY    PVIQWFW+ V     E + R LQFVTGTS+V
Sbjct: 849  ELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRV 908

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            P+ GF+ L G +GPQ F I + +GS   LP AHTCFN+LDLP Y + + L+
Sbjct: 909  PMNGFAELYGSNGPQLFTIEQ-WGSPEKLPRAHTCFNRLDLPPYETFEDLR 958
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>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
          Length = 959

 Score =  171 bits (433), Expect = 1e-42
 Identities = 85/171 (49%), Positives = 116/171 (67%), Gaps = 1/171 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            +L P G  I VT ENK EY+D V + R    ++ Q+NAF+EGF EL+P +LI IF++ E 
Sbjct: 773  DLEPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENEL 832

Query: 237  ELLISGLPDIDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ELL+ GL D+D++D + ++ Y +GY    PVIQWFW+ V     E + R LQFVTGTS+V
Sbjct: 833  ELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRV 892

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            P+ GF+ L G +GPQ F I + +GS   LP AHTCFN+LDLP Y + + L+
Sbjct: 893  PMNGFAELYGSNGPQLFTIEQ-WGSPEKLPRAHTCFNRLDLPPYETFEDLR 942
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>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 1004

 Score =  171 bits (433), Expect = 1e-42
 Identities = 85/171 (49%), Positives = 116/171 (67%), Gaps = 1/171 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            +L P G  I VT ENK EY+D V + R    ++ Q+NAF+EGF EL+P +LI IF++ E 
Sbjct: 818  DLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENEL 877

Query: 237  ELLISGLPDIDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ELL+ GL D+D++D + ++ Y +GY    PVIQWFW+ V     E + R LQFVTGTS+V
Sbjct: 878  ELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRV 937

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            P+ GF+ L G +GPQ F I + +GS   LP AHTCFN+LDLP Y + + L+
Sbjct: 938  PMNGFAELYGSNGPQLFTIEQ-WGSPEKLPRAHTCFNRLDLPPYETFEDLR 987
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>SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
            (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
            ubiquitin ligase 1) (hSMURF1)
          Length = 757

 Score =  171 bits (433), Expect = 1e-42
 Identities = 85/172 (49%), Positives = 114/172 (66%), Gaps = 3/172 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL P GRN+ VTEENK EYV      R    I  Q  A  +GFNELIP+ L+  F+ KE 
Sbjct: 569  ELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKEL 628

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            EL+I GL  IDL+D K+NT        S +++WFW+ V+ F +E +AR LQFVTG+++VP
Sbjct: 629  ELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVP 688

Query: 417  LEGFSALQ---GISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            L+GF ALQ   G +GP+ F IH    +T++LP AHTCFN++D+P Y S ++L
Sbjct: 689  LQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKL 740
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>ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-)|
            (Itch) (Atrophin-1-interacting protein 4) (AIP4)
            (NFE2-associated polypeptide 1) (NAPP1)
          Length = 903

 Score =  171 bits (433), Expect = 1e-42
 Identities = 83/175 (47%), Positives = 115/175 (65%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            E+   +L P G NI VTEENK EY+  VAE RL+  +  Q  AF EGFNE++P++ +  F
Sbjct: 714  EIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYF 773

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            + KE E+L+ G+ +IDL+D + +  Y  Y+  S  I WFW+ V+    E + R LQFVTG
Sbjct: 774  DAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 833

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            T ++P+ GF+ L G +GPQ+F I K  G  N LP +HTCFN+LDLP Y S +QL+
Sbjct: 834  TCRLPVGGFADLMGSNGPQKFCIEKV-GKENWLPRSHTCFNRLDLPPYKSYEQLK 887
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>SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
            (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
            ubiquitin ligase 1)
          Length = 731

 Score =  171 bits (433), Expect = 1e-42
 Identities = 85/172 (49%), Positives = 114/172 (66%), Gaps = 3/172 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL P GRN+ VTEENK EYV      R    I  Q  A  +GFNELIP+ L+  F+ KE 
Sbjct: 543  ELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKEL 602

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            EL+I GL  IDL+D K+NT        S +++WFW+ V+ F +E +AR LQFVTG+++VP
Sbjct: 603  ELIIGGLDKIDLNDWKSNTRLKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVP 662

Query: 417  LEGFSALQ---GISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            L+GF ALQ   G +GP+ F IH    +T++LP AHTCFN++D+P Y S ++L
Sbjct: 663  LQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKL 714
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>ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-)|
          Length = 864

 Score =  171 bits (433), Expect = 1e-42
 Identities = 83/175 (47%), Positives = 115/175 (65%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            E+   +L P G NI VTEENK EY+  VAE RL+  +  Q  AF EGFNE++P++ +  F
Sbjct: 675  EIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYF 734

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            + KE E+L+ G+ +IDL+D + +  Y  Y+  S  I WFW+ V+    E + R LQFVTG
Sbjct: 735  DAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTG 794

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            T ++P+ GF+ L G +GPQ+F I K  G  N LP +HTCFN+LDLP Y S +QL+
Sbjct: 795  TCRLPVGGFADLMGSNGPQKFCIEKV-GKENWLPRSHTCFNRLDLPPYKSYEQLK 848
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>WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2)
          Length = 870

 Score =  170 bits (430), Expect = 3e-42
 Identities = 82/175 (46%), Positives = 116/175 (66%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            +VT  EL  GG NIRVTEENK EY+  + + R T  +  Q  AF++GFNE+ P E +  F
Sbjct: 681  KVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYF 740

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            ++KE EL++ G+ +ID+ D + N  Y  Y+ +S  IQWFW++V+    E + R LQFVTG
Sbjct: 741  DEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTG 800

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            T ++P+ GF+ L G +GPQ+F I +  G    LP +HTCFN+LDLP Y S +QL+
Sbjct: 801  TCRLPVGGFAELIGSNGPQKFCIDRV-GKETWLPRSHTCFNRLDLPPYKSYEQLK 854
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>SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of deltex (EC|
            6.3.2.-)
          Length = 949

 Score =  169 bits (428), Expect = 5e-42
 Identities = 82/169 (48%), Positives = 110/169 (65%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL   G   RVTEENK EY+  + E R+T  I  Q   F+EGFNE++P E +  F+++E 
Sbjct: 765  ELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDEREL 824

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            EL++ G+ D+D++D + NT Y  Y+  S  + WFW+ V+    E +AR LQFVTGT +VP
Sbjct: 825  ELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVP 884

Query: 417  LEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            + GF+ L G +GPQRF I K  G    LP +HTCFN+LDLP Y S DQL
Sbjct: 885  VGGFAELMGSNGPQRFCIEKV-GKETWLPRSHTCFNRLDLPPYKSYDQL 932
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>WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2) (Atrophin-1-interacting
            protein 2) (AIP2)
          Length = 870

 Score =  168 bits (425), Expect = 1e-41
 Identities = 82/175 (46%), Positives = 116/175 (66%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            +VT  EL  GG +IRVTEENK EY+  + + R T  +  Q  AF++GFNE+ P E +  F
Sbjct: 681  KVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYF 740

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            ++KE EL++ G+ +ID+ D + +T Y  Y+  S  IQWFW++V+    E + R LQFVTG
Sbjct: 741  DEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTG 800

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            T ++P+ GF+ L G +GPQ+F I K  G    LP +HTCFN+LDLP Y S +QL+
Sbjct: 801  TCRLPVGGFAELIGSNGPQKFCIDKV-GKETWLPRSHTCFNRLDLPPYKSYEQLR 854
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>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 887

 Score =  167 bits (423), Expect = 2e-41
 Identities = 84/170 (49%), Positives = 116/170 (68%), Gaps = 1/170 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL  GG  + VT +NK EY+  V + R    I+ Q+ AF EGF ELIP++LI IF++ E 
Sbjct: 701  ELKTGGSEVVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENEL 760

Query: 237  ELLISGLPDIDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ELL+ GL D+D++D + +T+Y +GYS+   VI WFW+ V     E + R LQFVTGTS+V
Sbjct: 761  ELLMCGLGDVDVNDWREHTKYKNGYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRV 820

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            P+ GF+ L G +GPQ F + + +G+ + LP AHTCFN+LDLP Y S D+L
Sbjct: 821  PMNGFAELYGSNGPQSFTVEQ-WGTPDKLPRAHTCFNRLDLPPYESFDEL 869
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>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural|
            precursor cell expressed developmentally down-regulated
            protein 4)
          Length = 887

 Score =  167 bits (423), Expect = 2e-41
 Identities = 85/170 (50%), Positives = 116/170 (68%), Gaps = 1/170 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL  GG  I VT +NK EY+  V + R    I+ Q+ AF EGF ELIP++LI IF++ E 
Sbjct: 701  ELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENEL 760

Query: 237  ELLISGLPDIDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ELL+ GL D+D++D + +T+Y +GYS+   VI WFW+ V     E + R LQFVTGTS+V
Sbjct: 761  ELLMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRV 820

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            P+ GF+ L G +GPQ F + + +G+ + LP AHTCFN+LDLP Y S D+L
Sbjct: 821  PMNGFAELYGSNGPQSFTVEQ-WGTPDKLPRAHTCFNRLDLPPYESFDEL 869
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>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 1000

 Score =  166 bits (420), Expect = 4e-41
 Identities = 85/170 (50%), Positives = 115/170 (67%), Gaps = 1/170 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL  GG  I VT +NK EY+  V + R    I+ Q+ AF EGF ELIP++LI IF++ E 
Sbjct: 814  ELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENEL 873

Query: 237  ELLISGLPDIDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ELL+ GL D+D++D + +T+Y +GYS    VIQWFW+ V     E + R LQFVTGTS+V
Sbjct: 874  ELLMCGLGDVDVNDWREHTKYKNGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRV 933

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            P+ GF+ L G +GPQ F + + +G+   LP AHTCFN+LDLP Y S ++L
Sbjct: 934  PMNGFAELYGSNGPQSFTVEQ-WGTPEKLPRAHTCFNRLDLPPYESFEEL 982
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>WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1) (Atropin-1-interacting
            protein 5) (AIP5)
          Length = 922

 Score =  164 bits (415), Expect = 2e-40
 Identities = 80/175 (45%), Positives = 115/175 (65%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            +VT  +L  GG NI VTEENK EY+  + E R +  ++ Q  AF++GFNE++P + +  F
Sbjct: 733  KVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYF 792

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            ++KE E+++ G+ ++DL D + NT Y  Y+  S  I WFW+ V+    E + R LQFVTG
Sbjct: 793  DEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTG 852

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            T ++PL GF+ L G +GPQ+F I K  G    LP +HTCFN+LDLP Y S +QL+
Sbjct: 853  TCRLPLGGFAELMGSNGPQKFCIEKV-GKDTWLPRSHTCFNRLDLPPYKSYEQLK 906
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>WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1)
          Length = 918

 Score =  164 bits (415), Expect = 2e-40
 Identities = 80/175 (45%), Positives = 115/175 (65%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIF 221
            +VT  +L  GG NI VTEENK EY+  + E R +  ++ Q  AF++GFNE++P + +  F
Sbjct: 729  KVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYF 788

Query: 222  NDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTG 401
            ++KE E+++ G+ ++DL D + NT Y  Y+  S  I WFW+ V+    E + R LQFVTG
Sbjct: 789  DEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTG 848

Query: 402  TSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            T ++PL GF+ L G +GPQ+F I K  G    LP +HTCFN+LDLP Y S +QL+
Sbjct: 849  TCRLPLGGFAELMGSNGPQKFCIEKV-GKDTWLPRSHTCFNRLDLPPYKSYEQLK 902
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>SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.2.-) (Smad|
            ubiquitination regulatory factor 1 homolog) (DSmurf)
            (Lethal with a checkpoint kinase protein)
          Length = 1061

 Score =  155 bits (391), Expect = 1e-37
 Identities = 80/167 (47%), Positives = 108/167 (64%), Gaps = 4/167 (2%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL PGG +I VTEENK EYV     +R    I  Q  A  +GF ELIP  L+  F+++E 
Sbjct: 872  ELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPFDEREL 931

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP 416
            EL+I G+  ID++D + NT     +  +  + WFW++V+ +S E +AR LQFVTG+S+VP
Sbjct: 932  ELVIGGISSIDVNDWRNNTRLKHCTNETTQVLWFWQVVESYSSEMRARLLQFVTGSSRVP 991

Query: 417  LEGFSALQGIS---GPQRFQIH-KAYGSTNHLPSAHTCFNQLDLPEY 545
            L+GF ALQG +   GP+ F IH  A   T +LP AHTCFN++DLP Y
Sbjct: 992  LQGFRALQGSTGAVGPRLFTIHLTADVPTQNLPKAHTCFNRIDLPPY 1038
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>K0317_MOUSE (Q8CHG5) Protein KIAA0317|
          Length = 823

 Score =  130 bits (328), Expect = 2e-30
 Identities = 75/188 (39%), Positives = 115/188 (61%), Gaps = 4/188 (2%)
 Frame = +3

Query: 12   EEKLILYEKAEVTD--CELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGF 185
            EEK   Y K+   D   EL+ GG    VT  NK  Y++ +A++RL + ++ ++  F++G 
Sbjct: 627  EEK---YNKSGQLDKIVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGL 683

Query: 186  NELIPRELISIFNDKEFELLISGLPDIDLDDLKANTEYSG--YSIASPVIQWFWEIVQGF 359
            NEL+P  L++IF++ E ELL+ G  DI++ D KA+    G  +     V++WFW +V   
Sbjct: 684  NELVPENLLAIFDENELELLMCGTGDINVSDFKAHAVVVGGSWHFREKVMRWFWAVVSSL 743

Query: 360  SKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLP 539
            ++E+ AR LQF TG+S++P  GF+AL        FQI  A  + + LP+AHTCFNQL LP
Sbjct: 744  TQEELARLLQFTTGSSQLPPGGFAAL-----CPSFQIIAA-PTHSTLPTAHTCFNQLCLP 797

Query: 540  EYTSKDQL 563
             Y S +++
Sbjct: 798  TYDSYEEV 805
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>K0317_HUMAN (O15033) Protein KIAA0317|
          Length = 823

 Score =  130 bits (327), Expect = 3e-30
 Identities = 75/188 (39%), Positives = 114/188 (60%), Gaps = 4/188 (2%)
 Frame = +3

Query: 12   EEKLILYEKAEVTD--CELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGF 185
            EEK   Y K+   D   EL+ GG    VT  NK  Y++ +A++RL + ++ ++  F++G 
Sbjct: 627  EEK---YNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGL 683

Query: 186  NELIPRELISIFNDKEFELLISGLPDIDLDDLKANTEYSG--YSIASPVIQWFWEIVQGF 359
            NEL+P  L++IF++ E ELL+ G  DI + D KA+    G  +     V++WFW +V   
Sbjct: 684  NELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSL 743

Query: 360  SKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLP 539
            ++E+ AR LQF TG+S++P  GF+AL        FQI  A  + + LP+AHTCFNQL LP
Sbjct: 744  TQEELARLLQFTTGSSQLPPGGFAAL-----CPSFQIIAA-PTHSTLPTAHTCFNQLCLP 797

Query: 540  EYTSKDQL 563
             Y S +++
Sbjct: 798  TYDSYEEV 805
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>UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score =  121 bits (303), Expect = 2e-27
 Identities = 69/165 (41%), Positives = 97/165 (58%), Gaps = 2/165 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL  GG++I VT  N+  Y+  VA++RL   IRP   AF +G   ++  E + +F+ +E 
Sbjct: 901  ELKFGGKDIPVTGANRIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEI 960

Query: 237  ELLISGLP-DIDLDDLKANTEYSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSK 410
            ++LISG    + L+DLK+ T YSG YS   PVI+ FW +V+GF+ E+K + L+FVT  S+
Sbjct: 961  QVLISGAQVPVSLEDLKSFTNYSGGYSADHPVIKIFWRVVEGFTDEEKRKLLKFVTSCSR 1020

Query: 411  VPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEY 545
             PL GF  L        F IH        LP+A TC N L LPE+
Sbjct: 1021 PPLLGFKELY-----PAFCIHNGGSDLERLPTASTCMNLLKLPEF 1060
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>HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6.3.2.-)|
          Length = 910

 Score =  120 bits (302), Expect = 2e-27
 Identities = 69/171 (40%), Positives = 96/171 (56%), Gaps = 1/171 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            +LIP G    VT++N   YV +V +++L       ++AF  G + +I    + +FN  E 
Sbjct: 729  DLIPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIEL 788

Query: 237  ELLISGLPD-IDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
            ++LISG  D IDLDDLK+NTEY GY      I  FWE++  F  E+K  FL+FVT   + 
Sbjct: 789  QMLISGERDNIDLDDLKSNTEYGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQA 848

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            PL+GF AL       +F I  A      LP+A TC N L LP+Y +K  L+
Sbjct: 849  PLQGFKALD-----PKFGIRNAGTEKYRLPTASTCVNLLKLPDYRNKTILR 894
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>UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score =  119 bits (299), Expect = 5e-27
 Identities = 70/172 (40%), Positives = 99/172 (57%), Gaps = 2/172 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL  GG++I VT  N+  Y+  VA++RL   IR    AF +G   ++  E + +F+ +E 
Sbjct: 901  ELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEI 960

Query: 237  ELLISGLP-DIDLDDLKANTEYSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSK 410
            ++LISG    I L+DLK+ T YSG YS   PVI+ FW +V+GF+ E+K + L+FVT  S+
Sbjct: 961  QVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSR 1020

Query: 411  VPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
             PL GF  L        F IH        LP+A TC N L LPE+  +  L+
Sbjct: 1021 PPLLGFKELY-----PAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLR 1067
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>UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP|
            ubiquitin-protein ligase) (Oncogenic protein-associated
            protein E6-AP) (Human papillomavirus E6-associated
            protein) (NY-REN-54 antigen)
          Length = 875

 Score =  115 bits (289), Expect = 7e-26
 Identities = 67/172 (38%), Positives = 98/172 (56%), Gaps = 2/172 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELIS-IFNDKE 233
            +L   G  I +T EN+ E+V+  +++ L  ++  Q  AF  GF+ +     +  +F  +E
Sbjct: 695  DLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEE 754

Query: 234  FELLISGLPDIDLDDLKANTEYSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSK 410
             ELLI G  ++D   L+  TEY G Y+  S +I+ FWEIV  F+ E K  FLQF TGT +
Sbjct: 755  IELLICGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDR 814

Query: 411  VPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
             P+ G   L+ I       I K    T  LP++HTCFN L LPEY+SK++L+
Sbjct: 815  APVGGLGKLKMI-------IAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLK 859
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>UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic|
            protein-associated protein E6-AP)
          Length = 885

 Score =  113 bits (282), Expect = 4e-25
 Identities = 67/171 (39%), Positives = 95/171 (55%), Gaps = 2/171 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELIS-IFNDKE 233
            +L   G  I +T EN+ E+V   +++ L  ++  Q  AF  GF+ +     +  +F  +E
Sbjct: 705  DLKENGDKIPITNENRKEFVISYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEE 764

Query: 234  FELLISGLPDIDLDDLKANTEYSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSK 410
             ELLI G  ++D   L+  TEY G Y+  S VI+ FWEIV  F+ E K  FL F TGT +
Sbjct: 765  IELLICGSRNLDFQALEETTEYDGGYTRESVVIREFWEIVHSFTDEQKRLFLLFTTGTDR 824

Query: 411  VPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
             P+ G   L+ I       I K    T  LP++HTCFN L LPEY+SK++L
Sbjct: 825  APVGGLGKLKMI-------IAKNGPDTERLPTSHTCFNVLLLPEYSSKEKL 868
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>HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 892

 Score =  109 bits (273), Expect = 5e-24
 Identities = 63/180 (35%), Positives = 99/180 (55%), Gaps = 5/180 (2%)
 Frame = +3

Query: 42   EVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPR-ELISI 218
            E    EL   GRN+ +T+ NKHE+V +  E  L  +I PQ N F+ GF  +      I +
Sbjct: 703  EYVTVELCENGRNVPITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSIKL 762

Query: 219  FNDKEFELLISGLPD---IDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFL 386
            FN +E E L+ G  +    D   L++ T+Y  G+S  S  + WFWEI++ +    + + L
Sbjct: 763  FNSEELERLVCGDEEQTKFDFKSLRSVTKYVGGFSDDSRAVCWFWEIIESWDYPLQKKLL 822

Query: 387  QFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            QFVT + ++P  G S +     P +  +  ++ S + LP AHTCFN++ L  Y+SK +L+
Sbjct: 823  QFVTASDRIPATGISTI-----PFKISLLGSHDS-DDLPLAHTCFNEICLWNYSSKKKLE 876
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>HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3|
          Length = 1050

 Score =  109 bits (272), Expect = 6e-24
 Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 1/170 (0%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            +LIPGG N+ V ++N+ E+VD    +    ++     AF  GF ++   +++ +F   E 
Sbjct: 871  KLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSEL 930

Query: 237  ELLISGLPDIDLDDLKANTEYSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKV 413
              ++ G  + + ++L+    Y G YS   P ++ FWE    F  E K +FL F+TG+ ++
Sbjct: 931  RAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRI 990

Query: 414  PLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            P+ G ++LQ +       I        +LP AHTC+N LDLP+Y+SK+ L
Sbjct: 991  PIYGMASLQIV-------IQSTASGEEYLPVAHTCYNLLDLPKYSSKEIL 1033
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>HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 839

 Score =  107 bits (267), Expect = 2e-23
 Identities = 59/182 (32%), Positives = 95/182 (52%), Gaps = 3/182 (1%)
 Frame = +3

Query: 30   YEKAEVTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPREL 209
            ++++++   +L P G    VT ENKHEY     +  L  +I P   +F  GF  +I    
Sbjct: 649  FDESKIHYRQLCPDGSTQAVTRENKHEYFRLWMDFYLNRSIAPGFESFRNGFFHVIEGNS 708

Query: 210  ISIFNDKEFELLISGLPD--IDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKAR 380
              +F  +E E L+ G  +  +D+  L++ T Y  G+   SPV+QWFWEI+       + +
Sbjct: 709  FRLFGSEELEQLVCGSNEQSLDVSMLRSVTRYQGGFDDNSPVVQWFWEILSEMEYPQQRK 768

Query: 381  FLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQ 560
             L FVTG+ +VP  G + +        F+I +     + LP +HTCFN++ L EY  K+ 
Sbjct: 769  LLHFVTGSDRVPATGVTTIP-------FRISRIRSGADRLPLSHTCFNEICLHEYKDKET 821

Query: 561  LQ 566
            L+
Sbjct: 822  LR 823
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>UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB fusion protein 4)|
          Length = 1483

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 67/183 (36%), Positives = 94/183 (51%), Gaps = 14/183 (7%)
 Frame = +3

Query: 51   DCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNE---------LIPR 203
            D ELIPGG N  +   N  EY+  V +  L   I  Q+ AF+EGF++         L P 
Sbjct: 1293 DIELIPGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPD 1352

Query: 204  ELISIFNDKEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARF 383
            EL+ IF   E +  ++ L          N E+ GY++ S +I  F  I+  F K ++  F
Sbjct: 1353 ELVDIFGRVEEDWSMATLYT------NLNAEH-GYTMDSSIIHDFISIISAFGKHERRLF 1405

Query: 384  LQFVTGTSKVPLEGFSALQGISGPQRFQI---HKAYGST--NHLPSAHTCFNQLDLPEYT 548
            LQF+TG+ K+P+ GF +L       +F +   H   G T   +LPS  TC N L LP+YT
Sbjct: 1406 LQFLTGSPKLPIGGFKSLN-----PKFTVVLKHAEDGLTADEYLPSVMTCANYLKLPKYT 1460

Query: 549  SKD 557
            SKD
Sbjct: 1461 SKD 1463
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>HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4834

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 55/167 (32%), Positives = 90/167 (53%), Gaps = 3/167 (1%)
 Frame = +3

Query: 75   RNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEFELLISG 254
            ++  +T +N+ EYV     +RL      Q+ A  EG   ++P  L+S+F   E E ++ G
Sbjct: 4618 KHTHITLDNRAEYVRLAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCG 4676

Query: 255  LPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGF 428
             PDI L  LK+   Y G   ++ +IQWFWE+++ FS  +++ FL+FV G +++P  +  F
Sbjct: 4677 SPDIPLHLLKSVATYKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADF 4736

Query: 429  SALQGISGPQRFQIHKAYGSTNH-LPSAHTCFNQLDLPEYTSKDQLQ 566
                 +      Q+   Y   +H LP ++TCF  L LP Y+ K  L+
Sbjct: 4737 RGRDFV-----IQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLE 4778
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>HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4836

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 3/167 (1%)
 Frame = +3

Query: 75   RNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEFELLISG 254
            ++  +T +N+ EYV     +RL      Q+ A  EG   ++P  L+S+F   E E ++ G
Sbjct: 4620 KHTHITLDNRAEYVRLAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCG 4678

Query: 255  LPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGF 428
             PDI L  LK+   Y G   ++ ++QWFWE+++ FS  +++ FL+FV G +++P  +  F
Sbjct: 4679 SPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADF 4738

Query: 429  SALQGISGPQRFQIHKAYGSTNH-LPSAHTCFNQLDLPEYTSKDQLQ 566
                 +      Q+   Y   +H LP ++TCF  L LP Y+ K  L+
Sbjct: 4739 RGRDFV-----IQVLDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLE 4780
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>HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing|
            protein 1) (E3 ligase for inhibin receptor) (EULIR)
          Length = 2612

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 57/173 (32%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
 Frame = +3

Query: 48   TDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFND 227
            T  +L P G +  +T +N  EYVD + +  + T I+ Q+ AF +GFN++ P E +S F+ 
Sbjct: 2426 TAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSH 2485

Query: 228  KEFELLISG--LPDIDLDDLKANTEYS-GYSIASPVIQWFWEIVQGFSKEDKARFLQFVT 398
            +E ++++ G   P    +D+   TE   GY+  SP    F  ++ G S +++  FLQF T
Sbjct: 2486 EEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTT 2545

Query: 399  GTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKD 557
            G S +P  G + L     P+   + K   +    PS +TC + L LPEY+S++
Sbjct: 2546 GCSTLPPGGLANLH----PRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEE 2594
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>HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (Protein|
            hyperplastic discs)
          Length = 2885

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 56/177 (31%), Positives = 94/177 (53%), Gaps = 7/177 (3%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            ELIPGGR++ VT  N  EYV R  E+RL  +    + A  +G  +++P   +     ++ 
Sbjct: 2702 ELIPGGRDVAVTSSNIFEYVRRYTEYRLIKSQEKALEALKDGVFDVLPDNSMINLTAEDL 2761

Query: 237  ELLISGLPDIDLDDLKANTEYSGYSIASP-----VIQWFWEIVQGFSKEDKARFLQFVTG 401
             LL++G+ DI++  L + T ++  S   P       +WFW IV+  +  ++   + F TG
Sbjct: 2762 RLLLNGVGDINVSTLISYTTFNDESSEGPDKLLKFKKWFWSIVEKMNIMERQDLVYFWTG 2821

Query: 402  TSKVPL--EGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            +  +P   EGF  L  ++      I  A    +HLP+A+TC ++L +P Y+SK  L+
Sbjct: 2822 SPALPASEEGFQPLPSVT------IRPA--DDSHLPTANTCISRLYIPLYSSKSILR 2870
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>EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog) (100 kDa protein) (Fragment)
          Length = 920

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 56/178 (31%), Positives = 96/178 (53%), Gaps = 8/178 (4%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            ELIP G NI VT +N +EYV + AEHR+       ++A  +G  +++P+  +     ++F
Sbjct: 737  ELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDF 796

Query: 237  ELLISGLPDIDLDDLKANTEYSGYS--IASPVIQ---WFWEIVQGFSKEDKARFLQFVTG 401
             LL++G  ++++  L + T ++  S   A  ++Q   WFW IV+  S  ++   + F T 
Sbjct: 797  RLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVERMSMTERQDLVYFWTS 856

Query: 402  TSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            +  +P   EGF  +  I+  P   Q         HLP+A+TC ++L +P Y+SK  L+
Sbjct: 857  SPSLPASEEGFQPMPSITIRPPDDQ---------HLPTANTCISRLYVPLYSSKQILK 905
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>EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog) (hHYD) (Progestin-induced protein)
          Length = 2799

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 56/178 (31%), Positives = 96/178 (53%), Gaps = 8/178 (4%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            ELIP G NI VT +N +EYV + AEHR+       ++A  +G  +++P+  +     ++F
Sbjct: 2616 ELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDF 2675

Query: 237  ELLISGLPDIDLDDLKANTEYSGYS--IASPVIQ---WFWEIVQGFSKEDKARFLQFVTG 401
             LL++G  ++++  L + T ++  S   A  ++Q   WFW IV+  S  ++   + F T 
Sbjct: 2676 RLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTS 2735

Query: 402  TSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            +  +P   EGF  +  I+  P   Q         HLP+A+TC ++L +P Y+SK  L+
Sbjct: 2736 SPSLPASEEGFQPMPSITIRPPDDQ---------HLPTANTCISRLYVPLYSSKQILK 2784
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>EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog)
          Length = 2792

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 56/178 (31%), Positives = 96/178 (53%), Gaps = 8/178 (4%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            ELIP G NI VT +N +EYV + AEHR+       ++A  +G  +++P+  +     ++F
Sbjct: 2609 ELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDF 2668

Query: 237  ELLISGLPDIDLDDLKANTEYSGYS--IASPVIQ---WFWEIVQGFSKEDKARFLQFVTG 401
             LL++G  ++++  L + T ++  S   A  ++Q   WFW IV+  S  ++   + F T 
Sbjct: 2669 RLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTS 2728

Query: 402  TSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            +  +P   EGF  +  I+  P   Q         HLP+A+TC ++L +P Y+SK  L+
Sbjct: 2729 SPSLPASEEGFQPMPSITIRPPDDQ---------HLPTANTCISRLYVPLYSSKQILK 2777
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>YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protein C12B10.01c|
          Length = 1647

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 54/172 (31%), Positives = 88/172 (51%), Gaps = 3/172 (1%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            ELIP G +  VT  N  +Y++ V ++ +   ++ Q+ AF  GF+ + P   + +  + E 
Sbjct: 1459 ELIPDGASTPVTTFNVSDYLNYVIDYTVGKGVQQQLEAFQNGFSSVFPYTSLQVLTEHEL 1518

Query: 237  ELLISGLPDIDLDD---LKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTS 407
              L  G  D D      +K+     GY++ SP IQ    ++   + +++  FLQF+TG+ 
Sbjct: 1519 VTLF-GTVDEDWSYATLMKSIVADHGYTMESPTIQRLLTLMSQMNFQEQRDFLQFITGSR 1577

Query: 408  KVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQL 563
            K+P+ GF+ L       R      Y   ++LPS  TC N L LPEY+S + L
Sbjct: 1578 KLPIGGFAGLNPPLTVVRRLNEPPYVPDDYLPSVMTCVNYLKLPEYSSSEVL 1629
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>HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4912

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 48/162 (29%), Positives = 88/162 (54%), Gaps = 2/162 (1%)
 Frame = +3

Query: 75   RNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEFELLISG 254
            R   ++  N+ EYV      RL      Q+ A  +G +++IP  L+S+F+  E + ++ G
Sbjct: 4707 RYTHISPRNRAEYVRLALGFRLHE-FDEQVKAVRDGMSKVIPVPLLSLFSAAELQAMVCG 4765

Query: 255  LPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGF 428
             PDI L  LK+   Y G+  +S ++ WFWE+++ F+ ++++ FL+FV G +++P  +  F
Sbjct: 4766 SPDIPLGLLKSVATYKGFDPSSALVTWFWEVMEEFTNQERSLFLRFVWGRTRLPRTIADF 4825

Query: 429  SALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSK 554
                 +      Q+ +     + LP ++TCF  L +P Y+ K
Sbjct: 4826 RGRDFV-----LQVLEKNPPDHFLPESYTCFFLLKMPRYSCK 4862
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>TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TRIP12)|
          Length = 1992

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 8/173 (4%)
 Frame = +3

Query: 57   ELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEF 236
            EL  GG++I VT  N  EY+  V    L   +  Q ++F +GF  + P   +  F  +E 
Sbjct: 1803 ELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPEEL 1862

Query: 237  ELLISGLPDIDLDDLKANTEYS----GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGT 404
            + L+ G    D  D K   E      GY+  S  +++ +EI+  F  E +  FLQFVTG+
Sbjct: 1863 DQLLCG-SKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGS 1921

Query: 405  SKVPLEGFSALQGISGPQRFQIHKAYGSTNH----LPSAHTCFNQLDLPEYTS 551
             ++P+ GF +L     P    + K + ST +    LPS  TC N L LP+Y+S
Sbjct: 1922 PRLPVGGFRSL----NPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSS 1970
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>HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing protein 5|
            (Cyclin-E-binding protein 1)
          Length = 1024

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 46/173 (26%), Positives = 90/173 (52%), Gaps = 1/173 (0%)
 Frame = +3

Query: 51   DCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIRPQINAFMEGFNELIPRELISIFNDK 230
            D  LIP G +I V + NK +YV +   +    +++     F  GF ++   ++I +F+ +
Sbjct: 844  DTNLIPNGSSITVNQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLFHPE 903

Query: 231  EFELLISGLPDIDLDDLKANTEYS-GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTS 407
            E + +I G  D D    + N  Y  GY+ + P I  FW+     + E+K +FL F+TGT 
Sbjct: 904  ELKDVIVGNTDYDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTD 963

Query: 408  KVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQ 566
            ++ ++  + ++       F   +++   + +  A TCF+ L LP+Y++ + ++
Sbjct: 964  RLQMKDLNNMK-----ITFCCPESWNERDPI-RALTCFSVLFLPKYSTMETVE 1010
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>MUT7_CAEEL (P34607) Probable exonuclease mut-7 (EC 3.1.-.-)|
          Length = 910

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = -2

Query: 533 VQLVKASMSRGKMVGAAVRLVYLEP--LWPRYSLKRTETLQRYL 408
           V ++KA   RGK  G ++ + YLE   +W + S + TE  Q+YL
Sbjct: 72  VDMMKAMPDRGKTSGQSLAVWYLEDFGVWLKESGQETELRQKYL 115
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>PLSB_PASMU (Q9CLN7) Glycerol-3-phosphate acyltransferase (EC 2.3.1.15) (GPAT)|
          Length = 809

 Score = 30.4 bits (67), Expect = 3.6
 Identities = 12/38 (31%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
 Frame = +3

Query: 270 LDDLKANTEYSGYSIASPVIQWFW-EIVQGFSKEDKAR 380
           LD++ AN  Y G  +A   ++W W ++ QG   ++  R
Sbjct: 252 LDEIAANVNYEGLRVADRFLRWLWNKLYQGIDVQNADR 289
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>A85B_MYCSC (Q50397) Antigen 85-B precursor (85B) (Extracellular alpha-antigen)|
           (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B)
           (EC 2.3.1.-) (Fibronectin-binding protein B)
          Length = 330

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 9/25 (36%), Positives = 18/25 (72%)
 Frame = +3

Query: 270 LDDLKANTEYSGYSIASPVIQWFWE 344
           LD L+A  +Y+G+ I +P  +W+++
Sbjct: 79  LDGLRAQDDYNGWDINTPAFEWYYQ 103
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>A85B_MYCIT (Q49575) Antigen 85-B precursor (85B) (Extracellular alpha-antigen)|
           (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B)
           (EC 2.3.1.-) (Fibronectin-binding protein B)
          Length = 330

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 9/25 (36%), Positives = 18/25 (72%)
 Frame = +3

Query: 270 LDDLKANTEYSGYSIASPVIQWFWE 344
           LD L+A  +Y+G+ I +P  +W+++
Sbjct: 79  LDGLRAQDDYNGWDINTPAFEWYYQ 103
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>A85B_MYCAV (Q06947) Antigen 85-B precursor (85B) (Extracellular alpha-antigen)|
           (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B)
           (EC 2.3.1.-) (Fibronectin-binding protein B)
          Length = 330

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 9/25 (36%), Positives = 18/25 (72%)
 Frame = +3

Query: 270 LDDLKANTEYSGYSIASPVIQWFWE 344
           LD L+A  +Y+G+ I +P  +W+++
Sbjct: 79  LDGLRAQDDYNGWDINTPAFEWYYQ 103
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>A85B_MYCTU (P31952) Antigen 85-B precursor (85B) (Extracellular alpha-antigen)|
           (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B)
           (EC 2.3.1.-) (Fibronectin-binding protein B) (30 kDa
           extracellular protein)
          Length = 325

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 9/25 (36%), Positives = 18/25 (72%)
 Frame = +3

Query: 270 LDDLKANTEYSGYSIASPVIQWFWE 344
           LD L+A  +Y+G+ I +P  +W+++
Sbjct: 79  LDGLRAQDDYNGWDINTPAFEWYYQ 103
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>A85B_MYCKA (P21160) Antigen 85-B precursor (85B) (Extracellular alpha-antigen)|
           (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B)
           (EC 2.3.1.-) (Fibronectin-binding protein B)
          Length = 325

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 9/25 (36%), Positives = 18/25 (72%)
 Frame = +3

Query: 270 LDDLKANTEYSGYSIASPVIQWFWE 344
           LD L+A  +Y+G+ I +P  +W+++
Sbjct: 79  LDGLRAQDDYNGWDINTPAFEWYYQ 103
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>A85B_MYCBO (P12942) Antigen 85-B precursor (85B) (Extracellular alpha-antigen)|
           (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B)
           (EC 2.3.1.-) (Fibronectin-binding protein B)
          Length = 325

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 9/25 (36%), Positives = 18/25 (72%)
 Frame = +3

Query: 270 LDDLKANTEYSGYSIASPVIQWFWE 344
           LD L+A  +Y+G+ I +P  +W+++
Sbjct: 79  LDGLRAQDDYNGWDINTPAFEWYYQ 103
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>PAM1_YEAST (P37304) Protein PAM1|
          Length = 830

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 7/60 (11%)
 Frame = +3

Query: 123 VAEHRLTTAIRPQINAFMEGFNELIPRELISIFND-------KEFELLISGLPDIDLDDL 281
           V E+  ++ I P +N F + F +L PR+++++++        KE+EL    LP I  D L
Sbjct: 171 VHENSYSSDIIPILNTFQKLFQKLFPRDVVTLYDHSPSAFLAKEWEL---ALPQICFDPL 227
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>CENB2_HUMAN (Q15057) Centaurin-beta 2 (Cnt-b2)|
          Length = 778

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 20/63 (31%), Positives = 29/63 (46%)
 Frame = +3

Query: 348 VQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQ 527
           +Q F KED  +F        KV  E  +AL   +  QR + H+   +TN L +   CF  
Sbjct: 109 LQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRH 168

Query: 528 LDL 536
           + L
Sbjct: 169 IAL 171
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>TALA_DICDI (P54633) Filopodin (Talin homolog)|
          Length = 2492

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 15/37 (40%), Positives = 23/37 (62%)
 Frame = +3

Query: 45   VTDCELIPGGRNIRVTEENKHEYVDRVAEHRLTTAIR 155
            VT  + +PGG+NI V E+N  E ++ +AE  L+   R
Sbjct: 2235 VTLSKSLPGGQNIVVEEDNVLEDLEALAEDELSACAR 2271
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>PK1_NPVLD (P41720) Serine/threonine-protein kinase 1 (EC 2.7.11.1)|
          Length = 274

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 18/51 (35%), Positives = 29/51 (56%)
 Frame = +3

Query: 129 EHRLTTAIRPQINAFMEGFNELIPRELISIFNDKEFELLISGLPDIDLDDL 281
           EH+   AI P ++  M+ FN+   R   S+ + +E  L++  +PD DL DL
Sbjct: 49  EHKHFNAIEPFVHHLMK-FNKYFLRLFYSLHSLREHLLVMDYIPDGDLFDL 98
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>OBSCN_HUMAN (Q5VST9) Obscurin (Obscurin-myosin light chain kinase)|
            (Obscurin-MLCK) (Obscurin-RhoGEF)
          Length = 7968

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 17/59 (28%), Positives = 27/59 (45%)
 Frame = +3

Query: 324  VIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHL 500
            V++  WE   G  +   A+ + +        L  + AL+G+  P   Q+H AY S  HL
Sbjct: 7685 VVRQCWEKASG--RALAAKIIPYHPKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHL 7741
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>IDI2_METMP (Q6M174) Isopentenyl-diphosphate delta-isomerase (EC 5.3.3.2) (IPP|
           isomerase) (Isopentenyl pyrophosphate isomerase)
          Length = 355

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 24/85 (28%), Positives = 40/85 (47%)
 Frame = +3

Query: 228 KEFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTS 407
           ++ EL+ SG+ + DLDD+  + E  G  + +P+I     I  G  K  +      V    
Sbjct: 31  EDVELIHSGISNCDLDDIDTSIEIFGKKLNAPLI--VAAITGGHPKAKE------VNKNI 82

Query: 408 KVPLEGFSALQGISGPQRFQIHKAY 482
            + +E  +   G+ G QR  I K+Y
Sbjct: 83  AIAVEELNLGMGV-GSQRAAISKSY 106
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>ADR1_YEAST (P07248) Regulatory protein ADR1|
          Length = 1323

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = +3

Query: 204 ELISIFNDK---EFELLISGLPDIDLDDLKANTEYSGYSIASPVIQWFWEIVQGFSKEDK 374
           E + +F +     F ++   L D+DLD L+  T   GY  A    Q F  + QG  KE  
Sbjct: 639 EYLDLFKNNFLPHFPIIHPSLLDLDLDSLQRYTNEDGYDDAENA-QLFDRLSQGTDKEYD 697

Query: 375 ARFLQFVTGTSKVPLEGFSALQG 443
               Q ++ +  V L  F A  G
Sbjct: 698 YEHYQILSISKIVCLPLFMATFG 720


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,722,764
Number of Sequences: 219361
Number of extensions: 1766987
Number of successful extensions: 4761
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 4570
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4687
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 4700377760
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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