ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags16o08 |
|---|---|
| Clone Library Name | barley_pub |
>FPG_BACSU (O34403) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 84.0 bits (206), Expect = 4e-16 Identities = 56/189 (29%), Positives = 89/189 (47%), Gaps = 12/189 (6%) Frame = +2 Query: 71 VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVP--PISELGPDALFEP 244 ++ A++ K+ + DG + + D R+F + LF E P+S+LGP+ E Sbjct: 82 LHQAEEPDDKHVHVIFTMTDGTQLRYRDVRKFGTMHLFKPGEEAGELPLSQLGPEPDAEE 141 Query: 245 MSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEA 424 + D L+K +K LLDQ + G+GN DE L+++ HP A+ L+ ++ + Sbjct: 142 FTSAYLKDRLAKTNRAVKTALLDQKTVVGLGNIYVDEALFRAGVHPETKANQLSDKTIKT 201 Query: 425 LHQSIQEVVKYAVDVDADCDRFPVE--------WLFHHRWGKK--PGKVDGKKIEFITAG 574 LH I+ ++ A+D R + L H +GKK P K G I I G Sbjct: 202 LHAEIKNTLQEAIDAGGSTVRSYINSQGEIGMFQLQHFVYGKKDEPCKNCGTMISKIVVG 261 Query: 575 GRTTALCAR 601 GR T CA+ Sbjct: 262 GRGTHFCAK 270
>FPG_ACIAD (Q6FE90) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 271 Score = 82.8 bits (203), Expect = 8e-16 Identities = 44/133 (33%), Positives = 70/133 (52%) Frame = +2 Query: 71 VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMS 250 V +A D K+ + DDG E + D RRF + ++ ++ LGP+ L E + Sbjct: 78 VATAADELRKHDHLILTFDDGTELRYHDPRRFGCILWLNEESQSKLLNPLGPEPLSEDFN 137 Query: 251 VDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALH 430 D L K++GIK L+D + G+GN A E L+ HP Q ASSL++ AL Sbjct: 138 ADYLYQKLKSKQVGIKIALMDNHVVVGVGNIYATESLFNLGIHPAQPASSLSKPQILALV 197 Query: 431 QSIQEVVKYAVDV 469 Q I+ ++K+A+++ Sbjct: 198 QEIKRILKFAIEL 210
>FPG_OCEIH (Q8EPE6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 279 Score = 80.9 bits (198), Expect = 3e-15 Identities = 54/189 (28%), Positives = 92/189 (48%), Gaps = 13/189 (6%) Frame = +2 Query: 68 AVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETV--PPISELGPDALFE 241 +V+S D K++ +G E + D R+F + ++ E P+++LGPD Sbjct: 81 SVHSPGDPVKKHTHVTFYFSNGEELRYNDVRKFGTMHVYPIGEEFMHKPLNQLGPDPFDT 140 Query: 242 PMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCE 421 +++ F + L + IK LLDQS ++G+GN DE L+++ HPL+ S L+++ + Sbjct: 141 SFNLEYFYEKLKRTDRYIKTALLDQSIVTGLGNIYVDETLFRANVHPLKRCSKLSKQEVK 200 Query: 422 ALHQSIQEVVKYA-----------VDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFIT 568 L + +E ++ A V+ D F + L+ + KP +V G I I Sbjct: 201 KLQINAKETLRDAIKAGGTTIRSYVNTQGDMGMFQQD-LYVYGQHSKPCRVCGADIIKIK 259 Query: 569 AGGRTTALC 595 GGR T LC Sbjct: 260 VGGRGTHLC 268
>FPG_BACLD (Q65G93) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 79.3 bits (194), Expect = 9e-15 Identities = 54/185 (29%), Positives = 81/185 (43%), Gaps = 12/185 (6%) Frame = +2 Query: 83 DDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPE--TVPPISELGPDALFEPMSVD 256 D+ K+ DG E + D R+F + LF E T P+ +LGP+ + D Sbjct: 86 DEPLDKHVHVIFRFTDGSELRYRDVRKFGTMHLFKPGEELTELPLRQLGPEPFSSEFTAD 145 Query: 257 NFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQS 436 + L K +K LLDQ + G+GN DE L+++ HP A+ LT++ LH+ Sbjct: 146 YLRERLKKTNRSVKTALLDQRTVVGLGNIYVDEALFRAGIHPEATANKLTKKQTVLLHKE 205 Query: 437 IQEVVKYAVDVDADCDRFPVE----------WLFHHRWGKKPGKVDGKKIEFITAGGRTT 586 I + +K AV+ R + LF + +P K G IE GGR T Sbjct: 206 IIQTLKEAVEAGGSTVRSYINSQGEIGMFQLKLFVYGRKDEPCKKCGSPIEKTVVGGRGT 265 Query: 587 ALCAR 601 C + Sbjct: 266 HFCIK 270
>FPG_LACJO (Q74IB5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 79.3 bits (194), Expect = 9e-15 Identities = 53/169 (31%), Positives = 80/169 (47%), Gaps = 13/169 (7%) Frame = +2 Query: 128 DGLEFSFTDKRRFARVRLFDD--PETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKA 301 DG + D R+F R+ L + + I LGP+ E SV+ F+++LS+KK IK Sbjct: 100 DGTALRYADVRKFGRMHLVETGTEKQTTGIRHLGPEPNTEEFSVEYFINALSRKKKNIKN 159 Query: 302 LLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYA------- 460 LLDQ+ + G+GN DEVL+QSK HPL A S+ + L+ +I + A Sbjct: 160 TLLDQTVVCGLGNIYVDEVLWQSKIHPLSSAKSIPADKIVDLYHNINHTITVATKERGTT 219 Query: 461 ----VDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 +D + D + + G++ G +E I GR T C Sbjct: 220 VHTYLDANGDIGGYQNMLQVYGHAGEECNNC-GTILEKIKVNGRGTTFC 267
>FPG_GEOSL (Q74EG5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 79.0 bits (193), Expect = 1e-14 Identities = 56/181 (30%), Positives = 89/181 (49%), Gaps = 13/181 (7%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLF-DDPETVPPISELGPDALFEPMSVDNFVD 268 P KY + LDDG F D R+F V DP P +++LGP+ F P+ +++ Sbjct: 87 PGKYDHLDLVLDDGRTLRFRDPRKFGLVLWTGSDPLAHPLLAQLGPEP-FPPLFNGSYLF 145 Query: 269 SLSKKK-IGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 S S+K+ IK LL+D + G+GN A+E L++++ HP + A SL+ E C L ++ + Sbjct: 146 SRSRKRNAAIKLLLMDNRIVVGVGNIYANEALFRARIHPERAAGSLSEEDCATLATAVGD 205 Query: 446 VVKYA-----------VDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTAL 592 V++ A + + F + + + G KP V G I I G R+T Sbjct: 206 VLRDAIAEGDTTLHEFIATEVPSGYFRINPAVYGQTG-KPCTVCGTPIARIRLGNRSTWF 264 Query: 593 C 595 C Sbjct: 265 C 265
>FPG_PARUW (Q6MCT3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 78.6 bits (192), Expect = 2e-14 Identities = 43/123 (34%), Positives = 69/123 (56%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSL 274 S Y + ++G + F D R+F R L D E + I LGP+ L + + F D + Sbjct: 91 SPYVRIQFNFENGDQLRFHDTRKFGRWYLVSDVEEI--IGHLGPEPLLSSFTFELFEDMM 148 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 +K +K+LLLDQSFI G+GN DE L+++K HPL A+ + + + L+ SI+ V++ Sbjct: 149 KNRKTLLKSLLLDQSFIVGLGNIYVDEALWEAKLHPLIPANQINLKHLKILYHSIKYVLE 208 Query: 455 YAV 463 + Sbjct: 209 KGI 211
>FPG_LACPL (Q88WV4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 77.4 bits (189), Expect = 3e-14 Identities = 45/124 (36%), Positives = 69/124 (55%), Gaps = 2/124 (1%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPE--TVPPISELGPDALFEPMSVDNFVDS 271 K++ L D + + D R+F R+ L E TV + +GP+ + E +++ + Sbjct: 90 KHTHVIFHLTDDRDLLYNDTRKFGRMTLVPTGEENTVAGLRTIGPEPVAEQLTLAYMTAT 149 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 K K IK LLLDQS I+GIGN ADE L+ SK HP++ A+SLT + L Q+I + + Sbjct: 150 FGKSKKMIKPLLLDQSKIAGIGNIYADETLWMSKIHPMRPANSLTTDEIATLRQNIIDEM 209 Query: 452 KYAV 463 A+ Sbjct: 210 AMAI 213
>FPG_LACAC (Q5FIV8) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 76.3 bits (186), Expect = 7e-14 Identities = 44/123 (35%), Positives = 67/123 (54%), Gaps = 10/123 (8%) Frame = +2 Query: 128 DGLEFSFTDK--------RRFARVRLF--DDPETVPPISELGPDALFEPMSVDNFVDSLS 277 D +EF FTDK R+F R++L V I +LGP+ S +D+L Sbjct: 92 DHVEFVFTDKTALRYNDVRKFGRMQLIITGTERQVTGIKKLGPEPNTSEFSQQYLIDNLK 151 Query: 278 KKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKY 457 KK IK +LLDQ+ ++G+GN DE L+QSK HPL IA+ + + L ++I + + Sbjct: 152 KKHKNIKNVLLDQTTVAGLGNIYVDETLWQSKIHPLSIANKIPAKKVAGLWENINQTIAL 211 Query: 458 AVD 466 A++ Sbjct: 212 AIE 214
>FPG_CORGL (Q8NNV7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 285 Score = 75.9 bits (185), Expect = 1e-13 Identities = 56/154 (36%), Positives = 78/154 (50%), Gaps = 1/154 (0%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + IK D S + + VELD+G E F D+R F L Sbjct: 83 HLGMSGQMLIK-------------EPDAPISPHLRAKVELDNGDEVWFVDQRTFGYWWLG 129 Query: 185 DDPETVPP-ISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 D + VP +S + D L E +L +K IK LLL+Q +SGIGN ADE+L Sbjct: 130 DLVDGVPERVSHIATDVLDESADFSAIARNLKSRKSEIKRLLLNQEIVSGIGNIYADEML 189 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 +Q+K HPLQ A L+ E L Q+ ++V+ A+ Sbjct: 190 WQAKIHPLQRADRLSLARLEELLQAGKDVMTKAL 223
>FPG_LACSS (Q38VS5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 277 Score = 75.1 bits (183), Expect = 2e-13 Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPE--TVPPISELGPDALFEPMSVDNFVD 268 SK++ E DG + + D R+F R++L + + TV + +LGP+ +F Sbjct: 89 SKHTHVIFEFTDGQQMRYLDTRKFGRMQLIETGQENTVAGLKDLGPEPTPTTFLKADFYQ 148 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 L K IK LLLDQ ++G+GN DE L+ S HP A+ LTR + LH I Sbjct: 149 RLQKHHKAIKPLLLDQKVVTGLGNIYVDETLWLSHIHPETPANDLTRAETDRLHDEIIAE 208 Query: 449 VKYAVDVDADCDRFPVEWLFH--------HRWGKK--PGKVDGKKIEFITAGGRTTALCA 598 ++ A++ + H H +GKK P + G IE I R T C Sbjct: 209 LELAINHGGTTVNTFLNATGHAGAFQEMLHVYGKKGVPCERCGTPIEKIKVAQRGTHFCP 268 Query: 599 R 601 + Sbjct: 269 K 269
>FPG_BACSK (Q5WEG7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 74.7 bits (182), Expect = 2e-13 Identities = 53/182 (29%), Positives = 83/182 (45%), Gaps = 12/182 (6%) Frame = +2 Query: 86 DWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDD--PETVPPISELGPDALFEPMSVDN 259 D +K++ DG E + D R+F + LF P+++LG + E +V+ Sbjct: 87 DEKTKHTHVVFSFTDGSELRYADVRKFGTMHLFAKGAEHVAMPLAQLGVEPFSEQFTVEL 146 Query: 260 FVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSI 439 + +K IK LLDQ + G+GN DE L+ + HP + ASSL++E LH+ I Sbjct: 147 LEQAYAKTTRAIKTALLDQKTVVGLGNIYVDEALFHAGIHPERTASSLSKEEYHNLHKEI 206 Query: 440 QEVVKYAVDVDADCDRFPVE-----WLFH---HRWGKK--PGKVDGKKIEFITAGGRTTA 589 + +K A++ + V +F H +G+K P IE GGR T Sbjct: 207 KRTLKEAIEAGGSSIKSYVNGQGEIGMFQQQLHVYGRKQQPCHHCDTAIEKTVVGGRGTH 266 Query: 590 LC 595 C Sbjct: 267 YC 268
>FPG_THET8 (O50606) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 266 Score = 74.3 bits (181), Expect = 3e-13 Identities = 55/171 (32%), Positives = 83/171 (48%), Gaps = 15/171 (8%) Frame = +2 Query: 128 DGLEFSFTDKRRFAR---VRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIK 298 +G F D RRF R VR D E +P + LGP+ L E + F L + +K Sbjct: 89 EGRTLYFHDPRRFGRLFGVRRGDYRE-IPLLLRLGPEPLSEAFAFPGFFRGLKESARPLK 147 Query: 299 ALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDAD 478 ALLLDQ +G+GN ADE L++++ P + A SLT E L+++++EV+ AV++ Sbjct: 148 ALLLDQRLAAGVGNIYADEALFRARLSPFRPARSLTEEEARRLYRALREVLAEAVELGGS 207 Query: 479 C---------DRFPVEWLFHHR-WGKK--PGKVDGKKIEFITAGGRTTALC 595 D P + H +G++ P G+ +E GR T C Sbjct: 208 TLSDQSYRQPDGLPGGFQTRHAVYGREGLPCPACGRPVERRVVAGRGTHFC 258
>FPG_THET2 (Q72HN2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 266 Score = 74.3 bits (181), Expect = 3e-13 Identities = 55/171 (32%), Positives = 83/171 (48%), Gaps = 15/171 (8%) Frame = +2 Query: 128 DGLEFSFTDKRRFAR---VRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIK 298 +G F D RRF R VR D E +P + LGP+ L E + F L + +K Sbjct: 89 EGRTLYFHDPRRFGRLFGVRRGDYRE-IPLLLRLGPEPLSEAFAFPGFFRGLKESARPLK 147 Query: 299 ALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDAD 478 ALLLDQ +G+GN ADE L++++ P + A SLT E L+++++EV+ AV++ Sbjct: 148 ALLLDQRLAAGVGNIYADEALFRARLSPFRPARSLTEEEARRLYRALREVLAEAVELGGS 207 Query: 479 C---------DRFPVEWLFHHR-WGKK--PGKVDGKKIEFITAGGRTTALC 595 D P + H +G++ P G+ +E GR T C Sbjct: 208 TLSDQSYRQPDGLPGGFQTRHAVYGREGLPCPACGRPVERRVVAGRGTHFC 258
>FPG_GEOKA (Q5KWC3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 74.3 bits (181), Expect = 3e-13 Identities = 59/192 (30%), Positives = 90/192 (46%), Gaps = 12/192 (6%) Frame = +2 Query: 62 RSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF--DDPETVPPISELGPDAL 235 R AV SA + ++ DG E + D R+F + ++ ++ + PP++ELGP+ L Sbjct: 79 RYAVASALEPLEPHTHVVFCFTDGSELRYRDVRKFGTMHVYAKEEADRRPPLAELGPEPL 138 Query: 236 FEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRES 415 S + K K +KALLLDQ+ ++G GN DE L+++ P + A+SL+ + Sbjct: 139 SPAFSPAVLAERAVKTKRSVKALLLDQTVVAGFGNIYVDESLFRAGILPGRPAASLSSKE 198 Query: 416 CEALHQSIQEVVKYAVDVDADCDRFPVE-----WLFHHR---WGKK--PGKVDGKKIEFI 565 E LH+ + + AV R V F H +G+K P K G IE Sbjct: 199 IERLHEEMVATIGEAVMKGGSTVRTYVNTQGEAGAFQHSLFVYGRKGEPCKRCGTPIEKT 258 Query: 566 TAGGRTTALCAR 601 GR T C R Sbjct: 259 VVAGRGTHYCPR 270
>FPG_BACHD (Q9K855) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 74.3 bits (181), Expect = 3e-13 Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 12/169 (7%) Frame = +2 Query: 128 DGLEFSFTDKRRFARVRLFDD--PETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKA 301 DG E + D R+F + LF + PP+++LG + + S + LSK IK+ Sbjct: 101 DGTELRYQDVRKFGTMHLFQSGREQMEPPLAKLGVEPFSDQFSAKLLTERLSKTSRKIKS 160 Query: 302 LLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADC 481 LLDQ I G+GN DE L++++ HP ++A +T + LHQ+I + AV++ Sbjct: 161 ALLDQGIIVGLGNIYVDEALFRARIHPERLAKDVTVAEVKILHQAILNTLTEAVNLGGSS 220 Query: 482 DRFPVE-----WLFHHR---WGKK--PGKVDGKKIEFITAGGRTTALCA 598 + V +F R +G+K + G I GGR T C+ Sbjct: 221 IKSYVNGQGEMGMFQQRLDVYGRKGETCRQCGTPITKTVVGGRGTHFCS 269
>FPG_BACFI (P19210) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 74.3 bits (181), Expect = 3e-13 Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 12/168 (7%) Frame = +2 Query: 128 DGLEFSFTDKRRFARVRLFD--DPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKA 301 DG E + D R+F + LF E V P++ LG + E + + +++ K IK Sbjct: 101 DGEELRYQDVRKFGTMHLFPKGSEEKVLPLAHLGVEPFSEQFTSELLMNAFQKTNRKIKV 160 Query: 302 LLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADC 481 LLDQ + G+GN DE L++++ HP ++A SL++E LH++I ++ AV++ Sbjct: 161 ALLDQKTVVGLGNIYVDEALFRARIHPERLAHSLSKEEMAVLHKAIVSTLEEAVEMGGSS 220 Query: 482 DRFPVE-----WLFHHRWG-----KKPGKVDGKKIEFITAGGRTTALC 595 + V +F + G +P + G I GGR T C Sbjct: 221 IKSYVNGQGEMGMFQQKLGVYGRKNEPCRQCGTDILKTVVGGRGTHFC 268
>FPG_SYMTH (Q67R59) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 304 Score = 73.6 bits (179), Expect = 5e-13 Identities = 43/117 (36%), Positives = 66/117 (56%), Gaps = 2/117 (1%) Frame = +2 Query: 122 LDDGLEFSFTDKRRFARVRLFDDP-ETVPP-ISELGPDALFEPMSVDNFVDSLSKKKIGI 295 LDDG E + D+R+F L E +PP ++ LGP+ L + + L+ + I Sbjct: 98 LDDGGELRYADQRKFGGFHLLGPGGEGMPPGLANLGPEPLSPEFTPQVLAERLAGRHTSI 157 Query: 296 KALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 KA LL+Q+ ++G+GN ADE L+ ++ HP + A SLT E LH I+ V+ AV+ Sbjct: 158 KAALLNQALVAGLGNIYADEALFCARIHPAREAGSLTPAEVERLHGCIRRVLLRAVE 214
>FPG_ENTFA (Q837G3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 279 Score = 72.8 bits (177), Expect = 8e-13 Identities = 44/133 (33%), Positives = 67/133 (50%), Gaps = 2/133 (1%) Frame = +2 Query: 74 NSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF--DDPETVPPISELGPDALFEPM 247 + ADD +K++ DG + + D R+F R+ L + I LGP+ + Sbjct: 82 HQADDEIAKHTHVMFTFTDGTQLRYLDVRKFGRMTLVPKNQGHQYKGILALGPEPTPDVF 141 Query: 248 SVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEAL 427 + F L K IK LLLDQ ++G+GN DE L+Q++ HP Q A SL L Sbjct: 142 QLATFQQGLKKHHKAIKPLLLDQKLVTGLGNIYVDEALWQAQIHPEQPADSLKPAEVATL 201 Query: 428 HQSIQEVVKYAVD 466 +Q+I +V+ AV+ Sbjct: 202 YQAIIDVLARAVE 214
>FPG_LACLA (Q9CIK4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 271 Score = 72.4 bits (176), Expect = 1e-12 Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 19/179 (10%) Frame = +2 Query: 116 VELDDGLEFSFTDK-------RRFARVRLFDDPETVPPI--SELGPDALFEPMSVDNFVD 268 +E D L FTD+ R+F L + +P +GP+ +E F + Sbjct: 88 MEKHDHLALKFTDEQLIYADVRKFGTWELISTDQVLPYFLKKNIGPEPTYETFDEQIFRE 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 L K IK LL+Q+ ++G+GN DEVL+ +K HP ++A+ LT S LH SI E+ Sbjct: 148 KLQKSTKKIKPFLLEQTLVAGLGNIYVDEVLWLAKIHPEKVANQLTESSIHLLHDSIIEI 207 Query: 449 VKYAVDVDADCDR----------FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 ++ A+ + R E + + G+K + G +I+ I GR T C Sbjct: 208 LQKAIKLGGSSIRTYSALGSTGKMQDELRVYGKTGEKCVRC-GNEIQKIKVAGRGTHFC 265
>FPG_BACCR (Q817G5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/152 (29%), Positives = 76/152 (50%), Gaps = 6/152 (3%) Frame = +2 Query: 26 IYIKGVAVTKYKRSA----VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP 193 +Y+ + + R ++ D+ K++ DG E + D R+F + LF Sbjct: 63 LYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKG 122 Query: 194 ETVP--PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQ 367 E + P+++LGP+ M+ + L K IK +LLDQ + G+GN DEVL++ Sbjct: 123 EEMNQMPLADLGPEPFDAEMTPQYLQERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFR 182 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 S+ HP + ASSLT E E ++++ + AV Sbjct: 183 SQIHPEREASSLTVEEIERIYEATVTTLGEAV 214
>FPG_LISMF (Q71ZA3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 71.6 bits (174), Expect = 2e-12 Identities = 52/180 (28%), Positives = 89/180 (49%), Gaps = 13/180 (7%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRL---FDDPETVPPISELGPDALFEPMSVDNFV 265 SK++ +D E F D R+F + + + + ET I +LGP+ L + + +F Sbjct: 89 SKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGEGET-RSIKKLGPEPLTQAFTSTDFA 147 Query: 266 DSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 + K IK LLDQ ++G+GN ADE+ +++K P + A+SL+ + + + ++ + Sbjct: 148 TGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVRPERAANSLSDKEIKRIFEATKS 207 Query: 446 VVKYAVDVDADCDRFPVE---WLFHHR-----WGK--KPGKVDGKKIEFITAGGRTTALC 595 ++ AV + R V L ++ +GK +P V GK IE I GR T C Sbjct: 208 IMTEAVALGGSTVRTYVNSQGKLGQYQDKLKVYGKTDEPCVVCGKPIEKIKLNGRGTHFC 267
>FPG_GEOMG (Q39WD1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 266 Score = 71.6 bits (174), Expect = 2e-12 Identities = 49/178 (27%), Positives = 85/178 (47%), Gaps = 8/178 (4%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDD-PETVPPISELGPDALFEPMSVDNFVD 268 P K+ + DG F D R+F V D P T P ++ +GP+ L Sbjct: 87 PGKHDHLDIVFADGTVLRFHDPRKFGTVAWTTDAPATHPLLAAIGPEPLTATFDGAYLFA 146 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 +++ +K LL++ + ++G+GN A+E L+++ P + ASSL R CE L ++++EV Sbjct: 147 VTRTRRVAVKQLLMNAAIVAGVGNIYANEALFRAGIRPDRPASSLGRPECERLARTVREV 206 Query: 449 VKYAVDVDADCDRFPVEWLFHHR-----WGKKPGKVD--GKKIEFITAGGRTTALCAR 601 ++ ++D R E + +H +G+ G +E I G R+T C R Sbjct: 207 LQESID-QGSTYRVEEETVAYHPLNFDVYGRGTDACTRCGGALEEIRLGNRSTVFCPR 263
>FPG_RHOS4 (Q3IY64) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 282 Score = 71.6 bits (174), Expect = 2e-12 Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 2/156 (1%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + + G + ++ PS++ +E++ G +F D RRF + L Sbjct: 72 HLGMSGRMLVSGAQLGEFFHD-----HPAPSRHDHVVLEMEGGARITFNDARRFGAMDLV 126 Query: 185 --DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEV 358 + E P ++ LGP+ L L ++ IKA LLDQ ++G+GN EV Sbjct: 127 ATEAAEAHPLLAVLGPEPLGNAFDGAYLAARLEGRRTPIKAALLDQRIVAGLGNIYVCEV 186 Query: 359 LYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 L+++ P ++A SL+R E L I+EV+ A++ Sbjct: 187 LFRAGLAPGRLAGSLSRAEAEGLVPLIREVLLEAIE 222
>FPG_BACC1 (Q72ZF1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 71.6 bits (174), Expect = 2e-12 Identities = 44/152 (28%), Positives = 76/152 (50%), Gaps = 6/152 (3%) Frame = +2 Query: 26 IYIKGVAVTKYKRSA----VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP 193 +Y+ + + R ++ D+ K++ DG E + D R+F + LF Sbjct: 63 LYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKG 122 Query: 194 ETVP--PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQ 367 E + P+++LGP+ ++ + L K IK +LLDQ + G+GN DEVL++ Sbjct: 123 EEMNQMPLADLGPEPFDAELTPQYLQERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFR 182 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 S+ HP + ASSLT E E ++++ + AV Sbjct: 183 SQIHPEREASSLTAEEIERIYEATVTTLGEAV 214
>FPG_LEGPL (Q5WYY6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 71.2 bits (173), Expect = 2e-12 Identities = 50/179 (27%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDD-PETVPPISELGPDALFEPMSVDNFVD 268 P K+ + +++GL F D RRF D+ P P ++ LGP+ L + + + + Sbjct: 87 PQKHDHVDLHINNGLALRFRDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLR 146 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 + K IK+ ++D + GIGN A E L+ +K HP A +T E +L I+++ Sbjct: 147 KAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKI 206 Query: 449 VKYAVDVDA-------DCDRFPVEWLFHHR-WGKK--PGKVDGKKIEFITAGGRTTALC 595 ++ A++ D P + F + +G+K P V KIE + GR +A C Sbjct: 207 LESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFC 265
>FPG_LEGPH (Q5ZY18) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 71.2 bits (173), Expect = 2e-12 Identities = 50/179 (27%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDD-PETVPPISELGPDALFEPMSVDNFVD 268 P K+ + +++GL F D RRF D+ P P ++ LGP+ L + + + + Sbjct: 87 PQKHDHVDLHINNGLALRFCDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLR 146 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 + K IK+ ++D + GIGN A E L+ +K HP A +T E +L I+++ Sbjct: 147 KAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKI 206 Query: 449 VKYAVDVDA-------DCDRFPVEWLFHHR-WGKK--PGKVDGKKIEFITAGGRTTALC 595 ++ A++ D P + F + +G+K P V KIE + GR +A C Sbjct: 207 LESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFC 265
>FPG_LEGPA (Q5X7I9) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 71.2 bits (173), Expect = 2e-12 Identities = 50/179 (27%), Positives = 85/179 (47%), Gaps = 11/179 (6%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDD-PETVPPISELGPDALFEPMSVDNFVD 268 P K+ + +++GL F D RRF D+ P P ++ LGP+ L + + + + Sbjct: 87 PQKHDHVDLHINNGLALRFCDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLR 146 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 + K IK+ ++D + GIGN A E L+ +K HP A +T E +L I+++ Sbjct: 147 KAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKI 206 Query: 449 VKYAVDVDA-------DCDRFPVEWLFHHR-WGKK--PGKVDGKKIEFITAGGRTTALC 595 ++ A++ D P + F + +G+K P V KIE + GR +A C Sbjct: 207 LESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFC 265
>FPG_DESPS (Q6APT2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 276 Score = 71.2 bits (173), Expect = 2e-12 Identities = 38/128 (29%), Positives = 67/128 (52%), Gaps = 4/128 (3%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPET----VPPISELGPDALFEPMSVDNF 262 +K+ F+ LD+ EF + D RRF +R ++ +LGP+ L E + D Sbjct: 90 AKHDHFWCRLDNNQEFRYNDTRRFGSIRFLPAGKSRMLQESLYQKLGPEPLGETFTADYL 149 Query: 263 VDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQ 442 + K + IK ++D + GIGN A+E L+++ HP + S+ +E E L + IQ Sbjct: 150 RRAAEGKSLAIKNFIMDSHIVVGIGNIYANESLFKAAIHPARSVQSIEQEEWEKLARCIQ 209 Query: 443 EVVKYAVD 466 +++ +A+D Sbjct: 210 QILLHAID 217
>FPG_BACHK (Q6HCU5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 71.2 bits (173), Expect = 2e-12 Identities = 44/152 (28%), Positives = 76/152 (50%), Gaps = 6/152 (3%) Frame = +2 Query: 26 IYIKGVAVTKYKRSA----VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP 193 +Y+ + + R ++ D+ K++ DG E + D R+F + LF Sbjct: 63 LYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKG 122 Query: 194 ETVP--PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQ 367 E + P+++LGP+ ++ + L K IK +LLDQ + G+GN DEVL++ Sbjct: 123 EEMNQMPLADLGPEPFDAELTPQYLHERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFR 182 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 S+ HP + ASSLT E E ++++ + AV Sbjct: 183 SQIHPEREASSLTAEEIERIYEATVTTLGEAV 214
>FPG_BACCZ (Q633L1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 71.2 bits (173), Expect = 2e-12 Identities = 44/152 (28%), Positives = 76/152 (50%), Gaps = 6/152 (3%) Frame = +2 Query: 26 IYIKGVAVTKYKRSA----VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP 193 +Y+ + + R ++ D+ K++ DG E + D R+F + LF Sbjct: 63 LYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKG 122 Query: 194 ETVP--PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQ 367 E + P+++LGP+ ++ + L K IK +LLDQ + G+GN DEVL++ Sbjct: 123 EEMNQMPLADLGPEPFDAELTPQYLHERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFR 182 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 S+ HP + ASSLT E E ++++ + AV Sbjct: 183 SQIHPEREASSLTAEEIERIYEATVTTLGEAV 214
>FPG_BACAN (Q81L04) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 71.2 bits (173), Expect = 2e-12 Identities = 44/152 (28%), Positives = 76/152 (50%), Gaps = 6/152 (3%) Frame = +2 Query: 26 IYIKGVAVTKYKRSA----VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP 193 +Y+ + + R ++ D+ K++ DG E + D R+F + LF Sbjct: 63 LYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKG 122 Query: 194 ETVP--PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQ 367 E + P+++LGP+ ++ + L K IK +LLDQ + G+GN DEVL++ Sbjct: 123 EEMNQMPLADLGPEPFDAELTPQYLHERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFR 182 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 S+ HP + ASSLT E E ++++ + AV Sbjct: 183 SQIHPEREASSLTAEEIERIYEATVTTLGEAV 214
>FPG_LISIN (Q92BF1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 70.9 bits (172), Expect = 3e-12 Identities = 50/180 (27%), Positives = 88/180 (48%), Gaps = 13/180 (7%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRL---FDDPETVPPISELGPDALFEPMSVDNFV 265 +K++ +D E F D R+F + + + + ET I +LGP+ L ++ +F Sbjct: 89 TKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGESET-KSIKKLGPEPLTPAFTLADFA 147 Query: 266 DSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 + K IK LLDQ ++G+GN ADE+ +++K HP + A+SL+ + + ++ + Sbjct: 148 TGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVHPERAANSLSDKEINRIFEATKS 207 Query: 446 VVKYAVDVDADCDRFPVE---WLFHHR-----WGK--KPGKVDGKKIEFITAGGRTTALC 595 ++ AV + R V L ++ +GK +P + G IE I GR T C Sbjct: 208 IMTEAVALGGSTVRTYVNSQGKLGQYQDKLKVYGKTGEPCVICGTPIEKIKLNGRGTHFC 267
>FPG_STRPN (Q97R61) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 70.9 bits (172), Expect = 3e-12 Identities = 56/185 (30%), Positives = 85/185 (45%), Gaps = 12/185 (6%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLF-DDPETVPPISE-LGPDALFEPMSVDNFVDS 271 K++ F +DG + D R+F + L D V IS+ LGP+ + + F + Sbjct: 89 KHAHVFFHFEDGGTLVYEDVRKFGTMELLVPDLLDVYFISKKLGPEPSEQDFDLQVFQSA 148 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 L+K K IK+ LLDQ+ ++G+GN DEVL++++ HP + + +LT E A+H V+ Sbjct: 149 LAKSKKPIKSHLLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVL 208 Query: 452 KYAVDVDADCDRFPVEWL--------FHHRWGKKPGKV--DGKKIEFITAGGRTTALCAR 601 AV+ R FH + K + G IE I GGR T C Sbjct: 209 GQAVEKGGSTIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPN 268 Query: 602 TAEAD 616 D Sbjct: 269 CQRRD 273
>FPG_SYNY3 (P74290) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 286 Score = 70.9 bits (172), Expect = 3e-12 Identities = 38/132 (28%), Positives = 67/132 (50%), Gaps = 4/132 (3%) Frame = +2 Query: 83 DDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF--DDP--ETVPPISELGPDALFEPMS 250 D ++++ + + G E F D R F +V L D P E + + +LGP+ + Sbjct: 93 DQQRPRHTRVVLHFEGGWELRFVDTRTFGKVWLLPGDRPWAEVMTGLGQLGPEPFGADFT 152 Query: 251 VDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALH 430 + + L + +K LLDQ ++G+GN ADEVL+ HP ++ ++ + CE +H Sbjct: 153 AEYLYEKLKSSRRPLKNALLDQRLVAGLGNIYADEVLFFCGFHPTMASNQVSLQDCELIH 212 Query: 431 QSIQEVVKYAVD 466 Q IQ + A++ Sbjct: 213 QQIQATLTAAIE 224
>FPG_LISMO (Q8Y6W7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 70.5 bits (171), Expect = 4e-12 Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 13/180 (7%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRL---FDDPETVPPISELGPDALFEPMSVDNFV 265 SK++ +D E F D R+F + + + + ET I +LGP+ L + ++ +F Sbjct: 89 SKHTHIIFHFEDHTELRFLDVRKFGTMEVTNKYGEGET-RSIKKLGPEPLTQAFTLTDFA 147 Query: 266 DSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 + K IK LLDQ ++G+GN ADE+ +++K P + A+SL+ + + + ++ + Sbjct: 148 TGVKKTSRAIKTALLDQKLVAGVGNIYADEICFEAKVRPERAANSLSDKEIKRIFKATKS 207 Query: 446 VVKYAVDVDADCDRFPVE-----WLFHHR---WGK--KPGKVDGKKIEFITAGGRTTALC 595 ++ AV + R V + ++ +GK +P V G IE I GR T C Sbjct: 208 IMTEAVALGGSTVRTYVNSQGKLGQYQNKLKVYGKTDEPCVVCGTPIEKIKLNGRGTHFC 267
>FPG_VIBCH (Q9KVC5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 70.5 bits (171), Expect = 4e-12 Identities = 38/127 (29%), Positives = 69/127 (54%), Gaps = 1/127 (0%) Frame = +2 Query: 86 DWPS-KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNF 262 D+P+ K+ + + G + D RRF E+ + LGP+ L E + + Sbjct: 83 DFPAAKHDHVDLVMTSGKRLRYNDPRRFGAWLWCAPDESHEVLGRLGPEPLTEAFNAEYM 142 Query: 263 VDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQ 442 +D K+I +KA ++D + + G+GN A+E L+ S+ HPL+ A SL+ E + L +I+ Sbjct: 143 MDKARNKRIAVKAFIMDNAAVVGVGNIYANESLFTSRLHPLRPAHSLSLEEWQTLVANIK 202 Query: 443 EVVKYAV 463 +V++ A+ Sbjct: 203 QVLQVAI 209
>FPG_COREF (Q8FP17) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 284 Score = 70.1 bits (170), Expect = 5e-12 Identities = 51/155 (32%), Positives = 78/155 (50%), Gaps = 1/155 (0%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + +K S D + + + ELDDG E F D+R F L Sbjct: 82 HLGMSGQMLVK-------------SPDATLNPHLRARAELDDGNEVWFVDQRTFGYWWLG 128 Query: 185 DDPETVPP-ISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 + + VP +S + D L + + + L K IK LLL+Q +SGIGN ADE+L Sbjct: 129 ELVDGVPGRVSHIARDLLDDALDIPALAAVLKTKNTEIKRLLLNQEIVSGIGNIYADEML 188 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 +++ HP Q AS ++ AL ++ +EV+ A+D Sbjct: 189 WEAGIHPRQKASRISLTRLVALLEAGREVMTRALD 223
>FPG_STRR6 (Q8DQ33) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 69.7 bits (169), Expect = 7e-12 Identities = 54/190 (28%), Positives = 84/190 (44%), Gaps = 17/190 (8%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPI-------SELGPDALFEPMSVD 256 K++ F +DG + D R+F + L VP + +LGP+ + + Sbjct: 89 KHAHVFFHFEDGGTLVYEDVRKFGTMELL-----VPDLLDAYFISKKLGPEPSEQDFDLQ 143 Query: 257 NFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQS 436 F +L+K K IK+ LLDQ+ ++G+GN DEVL++++ HP + + +LT E A+H Sbjct: 144 VFQAALAKSKKPIKSHLLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQ 203 Query: 437 IQEVVKYAVDVDADCDRFPVEWL--------FHHRWGKKPGKV--DGKKIEFITAGGRTT 586 V+ AV+ R FH + K + G IE I GGR T Sbjct: 204 TIAVLGQAVEKGGSTIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGT 263 Query: 587 ALCARTAEAD 616 C D Sbjct: 264 HFCPNCQRRD 273
>FPG_ERWCT (Q6DAV4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 69.3 bits (168), Expect = 9e-12 Identities = 56/210 (26%), Positives = 89/210 (42%), Gaps = 11/210 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I + +Y P K+ + +D G +TD RRF Sbjct: 70 HLGMSGSLRI----LPEYSE---------PEKHDHVDLVMDSGKVLRYTDPRRFGAWLWT 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 D ET ++ LGP+ L D + KK IK ++D + G+GN A E L+ Sbjct: 117 DSLETSSVLAHLGPEPLEAEFFADYLYQASRGKKTAIKQWIMDNKVVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLFH 511 + HP + A SL + L + I++V++ +++ D F E + Sbjct: 177 AAGIHPDRAAGSLNENDADVLVRVIKQVLQLSIEQGGTTLRDFLQSDGKPGYFAQELRVY 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 R G +P + G IE G R+T C R Sbjct: 237 GRNG-EPCRTCGTPIETAKHGQRSTFFCRR 265
>FPG_DESVH (Q726D5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 364 Score = 69.3 bits (168), Expect = 9e-12 Identities = 52/178 (29%), Positives = 82/178 (46%), Gaps = 13/178 (7%) Frame = +2 Query: 101 YSKFFVELDDGLEFSFTDKRRFARVRLFDDPETV--PPISELGPDALFEPMSVDNFVDSL 274 +++ +L+ G F D R+F VR P +LGP+ L F L Sbjct: 185 HTRVVFDLEGGTRLFFDDARKFGYVRCITRRSLALWPFWRDLGPEPL--ETEARGFAARL 242 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 ++++ IKALLLDQ ++G+GN ADE L+++ P A +LT E ALH +Q+V++ Sbjct: 243 ARRRGRIKALLLDQKVVAGVGNIYADESLFRAGIRPDTQAHTLTPERLFALHGHLQDVLR 302 Query: 455 YAV-----------DVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 ++ D D F + + R G +P + G + GRTT C Sbjct: 303 ESIAECGSSIRDYRDAHGDAGAFQNSFRVYGR-GGQPCRHCGTTLATAQVAGRTTVFC 359
>FPG_NITEU (Q82S12) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 68.9 bits (167), Expect = 1e-11 Identities = 49/182 (26%), Positives = 83/182 (45%), Gaps = 12/182 (6%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFD-DPETVPPISELGPDALFEPMSVDNFVD 268 P + F +++D+G+ F D RRF + +D D P + +LGP+ L + Sbjct: 87 PQLHDHFDLQVDNGMMLRFRDPRRFGAILWWDGDIRQHPLLQKLGPEPLSDDFDGQFLYT 146 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 + IK +L++Q + GIGN A+E L+Q+ PL A SL CE L +++ Sbjct: 147 KTRGRNASIKEVLMNQHIVVGIGNIYANEALFQAGISPLAAAGSLNTMQCERLVDAVKAT 206 Query: 449 VKYAVDVD-------ADCD----RFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 + A+ DC+ F ++ + R G+ + G+ + G R+T C Sbjct: 207 LLRAIKAGGSSLRDFTDCEGSPGYFQQQYWVYGRAGQSCRQC-GELVSKTRQGQRSTFFC 265 Query: 596 AR 601 AR Sbjct: 266 AR 267
>FPG_WOLPM (Q73G10) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 68.6 bits (166), Expect = 2e-11 Identities = 50/181 (27%), Positives = 78/181 (43%), Gaps = 10/181 (5%) Frame = +2 Query: 83 DDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNF 262 D +K+ D F D RRF V + + + S+ G + L + S D Sbjct: 85 DQMRNKHDHVVFLFSDNTSIIFNDPRRFGLVIVLNKEQETDFFSDFGIEPLTDEFSGDYL 144 Query: 263 VDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQ 442 + L KK+ IK+ L+D I G+GN A E L++++ PL+ A +LT CE L I+ Sbjct: 145 QELLKNKKVNIKSALMDNKSIVGVGNIYASESLFRARISPLRSAKNLTYRECEKLAAEIK 204 Query: 443 EVVKYAVDVDADCDRFPVE-----WLFHHR---WGK--KPGKVDGKKIEFITAGGRTTAL 592 + A+ + + F + +GK KP K+ I I GR+T Sbjct: 205 NTLSDAIAAGGSTLKDYAQPSGSAGYFQNNFYVYGKVQKPCKICNNIITLIRQNGRSTYF 264 Query: 593 C 595 C Sbjct: 265 C 265
>FPG_STRA5 (P64153) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ + +L +G + D R+F L ++ LGP+ + + F Sbjct: 88 NKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSK 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 L+ K IK LLLDQ ++G+GN DEVL+ +K HP ++A+ LT LH+ I + Sbjct: 148 GLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRI 207 Query: 449 VKYAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKK----------IEFITAGGRTTALCA 598 + ++ R L +K +V GK I+ I GGR T C Sbjct: 208 LTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCP 267 Query: 599 R 601 R Sbjct: 268 R 268
>FPG_STRA3 (P64152) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ + +L +G + D R+F L ++ LGP+ + + F Sbjct: 88 NKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSK 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 L+ K IK LLLDQ ++G+GN DEVL+ +K HP ++A+ LT LH+ I + Sbjct: 148 GLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRI 207 Query: 449 VKYAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKK----------IEFITAGGRTTALCA 598 + ++ R L +K +V GK I+ I GGR T C Sbjct: 208 LTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCP 267 Query: 599 R 601 R Sbjct: 268 R 268
>FPG_STRA1 (Q3K028) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ + +L +G + D R+F L ++ LGP+ + + F Sbjct: 88 NKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSK 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 L+ K IK LLLDQ ++G+GN DEVL+ +K HP ++A+ LT LH+ I + Sbjct: 148 GLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRI 207 Query: 449 VKYAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKK----------IEFITAGGRTTALCA 598 + ++ R L +K +V GK I+ I GGR T C Sbjct: 208 LTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCP 267 Query: 599 R 601 R Sbjct: 268 R 268
>FPG_PHOLL (Q7MY36) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/177 (27%), Positives = 82/177 (46%), Gaps = 11/177 (6%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLS 277 K+ + + DG +TD RRF DD E ++ LGP+ L + + S Sbjct: 88 KHDHVDLVMADGKVLRYTDPRRFGAWLWSDDLERCSVLAHLGPEPLSDDFNGFYLYTRSS 147 Query: 278 KKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKY 457 KK IK L+D + G+GN A+E L+ + P + A +LT L ++I++V++ Sbjct: 148 NKKTLIKPWLMDNKLVVGVGNIYANEALFTAHIQPDRPAQTLTEREAHLLAETIKKVLQR 207 Query: 458 AVD-----------VDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 +++ D F E + R G +P ++ G++IE I G R+T C Sbjct: 208 SIERGGTTLRDFLQSDGKPGYFAQELFVYGRAG-EPCRICGEQIESIKLGQRSTFFC 263
>FPG_UREPA (Q9PQ76) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 68.2 bits (165), Expect = 2e-11 Identities = 44/177 (24%), Positives = 80/177 (45%), Gaps = 12/177 (6%) Frame = +2 Query: 101 YSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPP--ISELGPDALFEPMSVDNFVDSL 274 ++ +E ++G++ + D R+F +++ + + ++ D L S + L Sbjct: 93 HTHIIIEFNNGMQLRYNDTRQFGTFHIYEQQSFLDSKELKKIALDPLDNNFSAQYLYEKL 152 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 K IK LLDQS +SGIGN ADE+L+ +K P +A +LT ++ E + + Q ++ Sbjct: 153 KKSNKAIKTALLDQSVVSGIGNIYADEILFAAKIFPTILAKNLTLKNYEKITKEAQRILL 212 Query: 455 YAV----------DVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 ++ D + L H K+P ++ G I+ GR T C Sbjct: 213 LSIKNKGTTIHTYKFGNDETGLFQKMLLVHTHAKEPCQICGTIIQKTKVNGRGTYYC 269
>FPG_PASMU (P57910) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 68.2 bits (165), Expect = 2e-11 Identities = 47/182 (25%), Positives = 79/182 (43%), Gaps = 10/182 (5%) Frame = +2 Query: 86 DWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFV 265 D K+ + +++G + D RRF + + P +LGP+ L E D Sbjct: 84 DLIDKHDHLDIVVNNGKVVRYNDPRRFGAWLWTEKLDEFPLFLKLGPEPLSEEFDSDYLW 143 Query: 266 DSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 KK+ +K L+D + + G+GN A+E L+ HP + A SLT+ C L + I++ Sbjct: 144 QKSRKKQTALKTFLMDNAVVVGVGNIYANETLFLCNLHPQKTAGSLTKAQCGQLVEQIKQ 203 Query: 446 VVKYAVDVDADCDR----------FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 V+ A+ + + V+ L + KP G KIE + G R + C Sbjct: 204 VLSNAIQQGGTTLKDFLQPDGRPGYFVQELRVYGNKDKPCPTCGTKIESLVIGQRNSFYC 263 Query: 596 AR 601 + Sbjct: 264 PK 265
>FPG_PSESM (Q88AH6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 67.4 bits (163), Expect = 3e-11 Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLS 277 K+ +EL+ GL +TD RRF + DP + LGP+ L + + + Sbjct: 89 KHEHVDIELESGLALRYTDPRRFGAMLWSHDPHNHELLIRLGPEPLTDLFDGERLYERSR 148 Query: 278 KKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKY 457 K I +K ++D + + G+GN A E L+ + P + A ++R L I+ ++ Y Sbjct: 149 GKSIAVKPFIMDNAVVVGVGNIYATEALFAAGIDPRREARGISRARYLKLAIEIKRILAY 208 Query: 458 AVDVDADCDR----------FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 A++ R + + LF + G +P KV G + I G R + C + Sbjct: 209 AIERGGTTLRDFIGGDGKPGYFQQELFAYGRGGQPCKVCGTTLREIKLGQRASVYCPK 266
>FPG_SALTI (Q8Z2H2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 67.0 bits (162), Expect = 5e-11 Identities = 43/154 (27%), Positives = 75/154 (48%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I A+ K V+ + + +G +TD RRF Sbjct: 70 HLGMSGSLRILSEALPAEKHDHVD-------------LVMSNGKILRYTDPRRFGAWLWT 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 + E ++ LGP+ L + + + +KKK IK L+D + G+GN A E L+ Sbjct: 117 KELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 + HP ++ASSL+ E C+ L + I+ V+ +++ Sbjct: 177 AAGIHPDRLASSLSTEECDLLARVIKAVLLRSIE 210
>FPG_SALPA (Q5PC09) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 67.0 bits (162), Expect = 5e-11 Identities = 43/154 (27%), Positives = 75/154 (48%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I A+ K V+ + + +G +TD RRF Sbjct: 70 HLGMSGSLRILSEALPAEKHDHVD-------------LVMSNGKILRYTDPRRFGAWLWT 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 + E ++ LGP+ L + + + +KKK IK L+D + G+GN A E L+ Sbjct: 117 KELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 + HP ++ASSL+ E C+ L + I+ V+ +++ Sbjct: 177 AAGIHPDRLASSLSTEECDLLARVIKAVLLRSIE 210
>FPG_PSEU2 (Q4ZM34) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 67.0 bits (162), Expect = 5e-11 Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 10/178 (5%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLS 277 K+ +EL+ GL +TD RRF + DP + LGP+ L + + + Sbjct: 89 KHEHVDIELESGLALRYTDPRRFGAMLWSLDPHNHELLIRLGPEPLTDLFDGERLYERSR 148 Query: 278 KKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKY 457 K I +K ++D + + G+GN A E L+ + P + A S++R L I+ ++ Y Sbjct: 149 GKSIAVKPFVMDNAVVVGVGNIYATEALFAAGIDPRREAGSVSRARYLKLAIEIKRILAY 208 Query: 458 AVDVDADCDR----------FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 A++ R + + LF + G +P KV G + + G R + C + Sbjct: 209 AIERGGTTLRDFIGGDGKPGYFQQELFAYGRGGQPCKVCGTTLREVKLGQRASVYCPK 266
>FPG_SALTY (O54326) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 66.2 bits (160), Expect = 8e-11 Identities = 43/154 (27%), Positives = 75/154 (48%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I A+ K V+ + + +G +TD RRF Sbjct: 70 HLGMSGSLRILPEALPAEKHDHVD-------------LVMSNGKILRYTDPRRFGAWLWT 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 + E ++ LGP+ L + + + +KKK IK L+D + G+GN A E L+ Sbjct: 117 KELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 + HP ++ASSL+ E C+ L + I+ V+ +++ Sbjct: 177 AAGIHPDRLASSLSTEECDLLARVIKAVLLRSIE 210
>FPG_MYCPA (Q73VL9) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 282 Score = 66.2 bits (160), Expect = 8e-11 Identities = 44/119 (36%), Positives = 62/119 (52%), Gaps = 5/119 (4%) Frame = +2 Query: 122 LDDGLEFSFTDKRRFARVRLFD----DPETVP-PISELGPDALFEPMSVDNFVDSLSKKK 286 LDDG SF D+R F L D D +P P++ L D L V L +K Sbjct: 100 LDDGTVLSFADQRTFGGWMLADLLEVDGSILPRPVAHLARDPLDPRFDAAAVVKVLRRKH 159 Query: 287 IGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 IK LLDQ +SGIGN ADE L+++K H +IA+++T A+ + EV++ A+ Sbjct: 160 SEIKRQLLDQQVVSGIGNIYADEALWRAKVHGARIAATMTGRQLTAVLDAAAEVMRDAL 218
>FPG_SYNEN (P95744) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 283 Score = 66.2 bits (160), Expect = 8e-11 Identities = 40/113 (35%), Positives = 58/113 (51%), Gaps = 4/113 (3%) Frame = +2 Query: 137 EFSFTDKRRFARVRLFDDP----ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKAL 304 E F D+R F R E +P ++ L P+ L E +V L+ + IK Sbjct: 105 ELRFVDQRTFGRCWWLPPDCRVAEAIPALATLAPEPLSEAFTVAFLAARLAHCRRSIKTA 164 Query: 305 LLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 LLDQS ++G+GN ADE L+ S HP Q A +LT E + LH I +V++ + Sbjct: 165 LLDQSIVAGMGNIYADESLFLSGLHPTQSAHTLTPEQVQRLHGVICQVLREGI 217
>FPG_SYNEL (P59065) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 283 Score = 66.2 bits (160), Expect = 8e-11 Identities = 40/113 (35%), Positives = 58/113 (51%), Gaps = 4/113 (3%) Frame = +2 Query: 137 EFSFTDKRRFARVRLFDDP----ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKAL 304 E F D+R F R E +P ++ L P+ L E +V L+ + IK Sbjct: 105 ELRFVDQRTFGRCWWLPPDCRVAEAIPALATLAPEPLSEAFTVAFLAARLAHCRRSIKTA 164 Query: 305 LLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 LLDQS ++G+GN ADE L+ S HP Q A +LT E + LH I +V++ + Sbjct: 165 LLDQSIVAGMGNIYADESLFLSGLHPTQSAHTLTPEQVQRLHGVICQVLREGI 217
>FPG_NOCFA (Q5YS09) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 293 Score = 65.9 bits (159), Expect = 1e-10 Identities = 48/158 (30%), Positives = 77/158 (48%), Gaps = 5/158 (3%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + ++ A K + + +A LDDG E F D+R F L Sbjct: 84 HLGMSGQMLVQPAAAPVEKHAHIRAA-------------LDDGSELRFVDQRTFGGWALA 130 Query: 185 D----DPETVP-PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIA 349 D VP P++ + D L ++ V ++ K IK +LLDQ+ +SGIGN A Sbjct: 131 PLAEVDGSLVPEPVAHIARDPLDPRFDAESVVAAIRAKNSEIKRVLLDQTVVSGIGNIYA 190 Query: 350 DEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 DE L+++ + ++AS LTR + L ++ V+ A+ Sbjct: 191 DESLWRAGINGNRLASGLTRPAVRRLLAEVRAVMLEAL 228
>FPG_PSE14 (Q48CK1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 65.9 bits (159), Expect = 1e-10 Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLS 277 K+ +EL+ GL +TD RRF + DP + LGP+ L + + + Sbjct: 89 KHEHVDIELESGLALRYTDPRRFGAMLWSLDPHNHELLIRLGPEPLTDLFDGERLYERSR 148 Query: 278 KKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKY 457 K I +K ++D + + G+GN A E L+ + P + A ++R L I+ ++ Y Sbjct: 149 GKSIAVKPFVMDNAVVVGVGNIYATEALFAAGIDPRREAGGISRARYLKLAIEIKRILAY 208 Query: 458 AVDVDADCDR----------FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 A++ R + + LF + G +P KV G + I G R + C + Sbjct: 209 AIERGGTTLRDFIGGDGKPGYFQQELFVYGRGGQPCKVCGTTLREIKLGQRASVYCPK 266
>FPG_STRMU (P55045) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 65.5 bits (158), Expect = 1e-10 Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 2/173 (1%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPI--SELGPDALFEPMSVDNFVD 268 +K+ F LD G + D R+F L + ++GP+ + + F + Sbjct: 88 NKHFHLFFGLDGGSTLVYQDVRKFGTFELLPKSQVEAYFVQKKIGPEPNAKDFKLKPFEE 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 L+K IK LLLDQ ++G+GN DEVL+ +K P ++AS L + + +H + Sbjct: 148 GLAKSHKVIKTLLLDQHLVAGLGNIYVDEVLWAAKVDPERLASQLKKSEIKRIHDETIRI 207 Query: 449 VKYAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCARTA 607 ++ A++ R + + G+ DG + + G+T CAR A Sbjct: 208 LQLAIEKGGSTIR-----SYKNSLGE-----DGSMQDCLQVYGKTDQPCARCA 250
>FPG_SHISS (Q3YVZ7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/125 (29%), Positives = 64/125 (51%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 P K+ + + +G +TD RRF + E ++ LGP+ L + + + Sbjct: 86 PEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQK 145 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 +KKK IK L+D + G+GN A E L+ + HP ++ASSL+ CE L + I+ V+ Sbjct: 146 CAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVL 205 Query: 452 KYAVD 466 +++ Sbjct: 206 LRSIE 210
>FPG_SHIFL (P64149) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/125 (29%), Positives = 64/125 (51%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 P K+ + + +G +TD RRF + E ++ LGP+ L + + + Sbjct: 86 PEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQK 145 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 +KKK IK L+D + G+GN A E L+ + HP ++ASSL+ CE L + I+ V+ Sbjct: 146 CAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVL 205 Query: 452 KYAVD 466 +++ Sbjct: 206 LRSIE 210
>FPG_SHIDS (Q329M2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/125 (29%), Positives = 64/125 (51%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 P K+ + + +G +TD RRF + E ++ LGP+ L + + + Sbjct: 86 PEKHDHVDLVMSNGKVLRYTDPRRFGAWLWAKELEGHNVLAHLGPEPLSDDFNGEYLHQK 145 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 +KKK IK L+D + G+GN A E L+ + HP ++ASSL+ CE L + I+ V+ Sbjct: 146 CAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVL 205 Query: 452 KYAVD 466 +++ Sbjct: 206 LRSIE 210
>FPG_SHIBS (Q31UZ1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/125 (29%), Positives = 64/125 (51%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 P K+ + + +G +TD RRF + E ++ LGP+ L + + + Sbjct: 86 PEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQK 145 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 +KKK IK L+D + G+GN A E L+ + HP ++ASSL+ CE L + I+ V+ Sbjct: 146 CAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVL 205 Query: 452 KYAVD 466 +++ Sbjct: 206 LRSIE 210
>FPG_ECOLI (P05523) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/125 (29%), Positives = 64/125 (51%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 P K+ + + +G +TD RRF + E ++ LGP+ L + + + Sbjct: 86 PEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQK 145 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 +KKK IK L+D + G+GN A E L+ + HP ++ASSL+ CE L + I+ V+ Sbjct: 146 CAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVL 205 Query: 452 KYAVD 466 +++ Sbjct: 206 LRSIE 210
>FPG_ECO57 (P64148) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/125 (29%), Positives = 64/125 (51%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 P K+ + + +G +TD RRF + E ++ LGP+ L + + + Sbjct: 86 PEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQK 145 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 +KKK IK L+D + G+GN A E L+ + HP ++ASSL+ CE L + I+ V+ Sbjct: 146 CAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVL 205 Query: 452 KYAVD 466 +++ Sbjct: 206 LRSIE 210
>FPG_XANCP (Q8P3C4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 65.5 bits (158), Expect = 1e-10 Identities = 53/209 (25%), Positives = 89/209 (42%), Gaps = 11/209 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V D P + + L +G F D RRF + Sbjct: 72 HLGMSGSL-------------RVLPGDTPPRAHDHVDISLQNGRVLRFNDPRRFGCLLWQ 118 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 D ET ++ LGP+ L + D ++ +K L+DQ+ + G+GN A E L+ Sbjct: 119 RDCETHELLASLGPEPLSAAFTGDYLHALACGRRAAVKTFLMDQAVVVGVGNIYAAESLH 178 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYA-----------VDVDADCDRFPVEWLFH 511 ++ PL+ A ++RE L +++E++ YA + D F E + + Sbjct: 179 RAGISPLREAGKVSRERYRRLADAVKEILAYAIQRGGTTLRDFISPDGAPGYFEQELMVY 238 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCA 598 R G+ G +++ T G R T CA Sbjct: 239 GREGEACRHCGG-ELKHATIGQRATVWCA 266
>FPG_XANC8 (Q4UNU6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 65.5 bits (158), Expect = 1e-10 Identities = 53/209 (25%), Positives = 89/209 (42%), Gaps = 11/209 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V D P + + L +G F D RRF + Sbjct: 72 HLGMSGSL-------------RVLPGDTPPRAHDHVDISLQNGRVLRFNDPRRFGCLLWQ 118 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 D ET ++ LGP+ L + D ++ +K L+DQ+ + G+GN A E L+ Sbjct: 119 RDCETHELLASLGPEPLSAAFTGDYLHALACGRRAAVKTFLMDQAVVVGVGNIYAAESLH 178 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYA-----------VDVDADCDRFPVEWLFH 511 ++ PL+ A ++RE L +++E++ YA + D F E + + Sbjct: 179 RAGISPLREAGKVSRERYRRLADAVKEILAYAIQRGGTTLRDFISPDGAPGYFEQELMVY 238 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCA 598 R G+ G +++ T G R T CA Sbjct: 239 GREGEACRHCGG-ELKHATIGQRATVWCA 266
>FPG_WOLTR (Q5GS47) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 65.5 bits (158), Expect = 1e-10 Identities = 54/208 (25%), Positives = 84/208 (40%), Gaps = 11/208 (5%) Frame = +2 Query: 5 HEGMAGA-IYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRL 181 H GM+G IY KG + +K+ D F D R+F V + Sbjct: 72 HLGMSGKLIYAKG--------------EQAQNKHDHVIFSFSDNTSIIFNDPRKFGLVII 117 Query: 182 FDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 + + V ++ G + + + D L KK+ IK+ L++ I GIGN A E L Sbjct: 118 LNKEQEVNFFNDFGIEPFTDEFNGDYLQKLLKSKKVNIKSALMNNKLIVGIGNIYASESL 177 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV--------DVDADCDRFPVEWLFHHR 517 ++++ PL+ A LT + CE L I+ + A+ D + Sbjct: 178 FRARISPLRSAQDLTYKECEKLATEIKNTLSDAIIAGGSTLKDYAQPSGSVGYFQNSFYV 237 Query: 518 WGK--KPGKVDGKKIEFITAGGRTTALC 595 +GK KP K+ I I GR+T C Sbjct: 238 YGKVQKPCKICNNTITLIRQNGRSTYFC 265
>FPG_SERMA (Q9X981) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 65.5 bits (158), Expect = 1e-10 Identities = 54/210 (25%), Positives = 91/210 (43%), Gaps = 11/210 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ R +D K+ + +++G+ +TD RRF Sbjct: 70 HLGMSGSL-----------RMLREENEDEAGKHDHVDLVINNGMILRYTDPRRFGAWLWC 118 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 +D T ++ LGP+ L E + D + K+ IK L+D + G+GN A E L+ Sbjct: 119 EDLATSSVLAHLGPEPLSEAFNGDYLYEKSRNKRTLIKPWLMDNKLVVGVGNIYASESLF 178 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLFH 511 + P + A SLT+ L ++I+ V++ +++ D F E + Sbjct: 179 SAGILPDRPAGSLTKAEAALLAKTIKAVLQRSIEQGGTTLRDFLQSDGKPGYFAQELQVY 238 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 R G +P + G IE G R+T C R Sbjct: 239 GRAG-EPCRTCGTPIESAKHGQRSTFFCRR 267
>FPG_ECOL6 (Q8FC87) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/125 (29%), Positives = 63/125 (50%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 P K+ + + +G +TD RRF + E ++ LGP+ L + + + Sbjct: 86 PEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQK 145 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 KKK IK L+D + G+GN A E L+ + HP ++ASSL+ CE L + I+ V+ Sbjct: 146 CEKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVL 205 Query: 452 KYAVD 466 +++ Sbjct: 206 LRSIE 210
>FPG_HAEI8 (Q4QLW2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 65.1 bits (157), Expect = 2e-10 Identities = 52/210 (24%), Positives = 94/210 (44%), Gaps = 11/210 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I + SA++ K+ + +++G + D RRF Sbjct: 70 HLGMSGSVRIVP------QDSAID-------KHDHIDIVVNNGKLLRYNDPRRFGAWLWT 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 ++ + +LGP+ L + + + +K +K L+D + + G+GN A+E L+ Sbjct: 117 ENLDDFHLFLKLGPEPLSDEFNAEYLFKKSRQKSTALKTFLMDNAVVVGVGNIYANESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAV-----------DVDADCDRFPVEWLFH 511 HPL++A +LTR C +L +I++V++ A+ D F E L + Sbjct: 177 ICGIHPLKLAKNLTRNQCFSLVNTIKDVLRKAIIQGGTTLKDFLQPDGRPGYFAQELLVY 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 KP G KIE + G R + C + Sbjct: 237 GN-KDKPCPKCGGKIESLIIGQRNSFFCPK 265
>FPG_SALCH (Q57IA7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 64.7 bits (156), Expect = 2e-10 Identities = 43/154 (27%), Positives = 74/154 (48%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I A+ K V+ + + +G +TD RRF Sbjct: 70 HLGMSGSLRILPEALPAEKHDHVD-------------LVMSNGKILRYTDPRRFGAWLWT 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 + E ++ LGP+ L + + +KKK IK L+D + G+GN A E L+ Sbjct: 117 KELEGHNVLAHLGPEPLSGEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 + HP ++ASSL+ E C+ L + I+ V+ +++ Sbjct: 177 AAGIHPDRLASSLSTEECDLLARVIKAVLLRSIE 210
>FPG_CARHZ (Q3ABL4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 262 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/123 (31%), Positives = 69/123 (56%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLS 277 K++ +L D LE F D R+F F+ PE +GP+ L + + + L Sbjct: 91 KHTHAIFDLGD-LELHFNDIRQFGGFS-FEMPE-------IGPEPLEDEFTPEYLKTKLK 141 Query: 278 KKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKY 457 + +KA+LLDQ I+GIGN ADE+L+++ P +IA+SL+ + E L ++I++++ Sbjct: 142 ASQKNLKAVLLDQKIIAGIGNIYADEILFEAGLSPKRIAASLSEDEAEELFKAIRKILAL 201 Query: 458 AVD 466 ++ Sbjct: 202 GIE 204
>FPG_PROMP (Q7V2X4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 291 Score = 64.3 bits (155), Expect = 3e-10 Identities = 47/185 (25%), Positives = 88/185 (47%), Gaps = 15/185 (8%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP----ETVPPISELGPDALFEPMSVDN 259 P K+++ + ++ E + D R F ++ D + + LGP+ E +V+ Sbjct: 105 PCKHTRIRLFDNNNNELRYIDVRSFGQMWWVRDGLSPNNIIKGLGTLGPEPFSESFNVNY 164 Query: 260 FVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSI 439 +S K IK++LLDQ+ I+GIGN ADE LY + P + A ++ + + L +++ Sbjct: 165 LKKVISNKTRSIKSILLDQTIIAGIGNIYADESLYSAGISPFREARTINKNEIKRLRRAV 224 Query: 440 QEVVKYAV-----------DVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTT 586 +V+K ++ D++ + F ++ + R GKK + IE GR+T Sbjct: 225 VDVLKKSIGAGGTTFSDFRDLEGENGNFGLQTNVYRRTGKKCRQCK-NLIERQKISGRST 283 Query: 587 ALCAR 601 C + Sbjct: 284 HWCRK 288
>FPG_RICFE (Q4UMW5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 275 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/123 (30%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPI-SELGPDALFEPMSVDNFVDSL 274 K+ +L +G + F D RRF + F + + LG + L + ++++ L Sbjct: 90 KHDHVIFDLSNGEKLIFNDTRRFGMIYNFKTNFLEKELFNNLGVEPLSDSLTLEYLKSKL 149 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 +KI IK L++D I G+GN A E LY ++ HP ++ S+L + E+L +SI+EV+ Sbjct: 150 ITRKIPIKNLIMDNRIIVGVGNIYASESLYLARIHPDKLGSNLRDDEIESLIKSIREVLA 209 Query: 455 YAV 463 A+ Sbjct: 210 KAI 212
>FPG_MANSM (Q65R59) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/154 (25%), Positives = 72/154 (46%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I SA D K+ + +++G + D RRF Sbjct: 70 HLGMSGSVRIV-------------SARDPVDKHDHLDIVMNNGKIMRYNDPRRFGTWLWS 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 + + +LGP+ L + + + KK+ +K L+D S + G+GN A+E L+ Sbjct: 117 ANLDEFHLFLKLGPEPLSDEFNAEYLFKKSRKKQTPVKNFLMDNSVVVGVGNIYANETLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 HP +I + LT+ C L + I++ +K A++ Sbjct: 177 MCGLHPEKITAKLTKAQCALLVEKIKQELKRAIE 210
>FPG_DEIRA (Q9RX22) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 279 Score = 63.5 bits (153), Expect = 5e-10 Identities = 54/184 (29%), Positives = 86/184 (46%), Gaps = 19/184 (10%) Frame = +2 Query: 101 YSKFFVELDDGLEFSFTDKRRFARVRLF--DDPETVPPISELGPDALFEPMSVDNFVDSL 274 +++ EL G + F D RRF +V D ++P ++ +GP+ L + + FV +L Sbjct: 90 HTRVTFELGSGEKLYFNDPRRFGKVVAVAPGDYASMPTLAAMGPEPLSDDFTEAEFV-AL 148 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 + + +K LL Q +SG+GN ADE L+ ++ HP Q + L + L+++I+EV+ Sbjct: 149 AARCGPVKPWLLSQKPVSGVGNIYADESLWHARLHPAQ--TRLNADEAGRLYRAIREVMA 206 Query: 455 YAVDV---------------DADCDRFPVEWLFHHRWGKKPGKVD--GKKIEFITAGGRT 583 AVD D + F HH +G+ D G IE I G R Sbjct: 207 AAVDKGGSSLGNGVGNYRQHDGEGGGFQHS---HHVYGRAGQPCDRCGTPIEKIVLGQRG 263 Query: 584 TALC 595 T C Sbjct: 264 THFC 267
>FPG_STRT1 (Q5M0P0) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 63.5 bits (153), Expect = 5e-10 Identities = 46/173 (26%), Positives = 76/173 (43%), Gaps = 2/173 (1%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFD--DPETVPPISELGPDALFEPMSVDNFVD 268 +K+ F +LDDG + D R+F L D E ELGP+ + F Sbjct: 88 NKHFHLFFKLDDGSTLVYQDVRKFGTFDLLDRKQEEAYFTRKELGPEPTKKTFKYVPFER 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 +L IK LLL+Q ++G+GN DEVL+ +K HP A+ L++ + + +H + Sbjct: 148 ALMHSGKSIKPLLLEQKLVAGLGNIYVDEVLWAAKVHPETPANKLSKAAMKRVHDQTIAI 207 Query: 449 VKYAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCARTA 607 ++ + R + + G+ DG ++ G+T C R A Sbjct: 208 LQLGIAKGGSTIR-----TYRNALGE-----DGTMQNYLQVYGKTGQPCPRCA 250
>FPG_HAEIN (P44948) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 63.5 bits (153), Expect = 5e-10 Identities = 51/210 (24%), Positives = 93/210 (44%), Gaps = 11/210 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I + SA++ K+ + +++G + D RRF Sbjct: 70 HLGMSGSVRIVP------QDSAID-------KHDHIDIVVNNGKLLRYNDPRRFGAWLWT 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 ++ + +LGP+ L + + + +K +K L+D + + G+GN +E L+ Sbjct: 117 ENLDDFHLFLKLGPEPLSDEFNAEYLFKKSRQKSTALKTFLMDNAVVVGVGNIYTNESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAV-----------DVDADCDRFPVEWLFH 511 HPL++A +LTR C +L +I++V++ A+ D F E L + Sbjct: 177 ICGIHPLKLAKNLTRNQCFSLVNTIKDVLRKAIIQGGTTLKDFLQPDGRPGYFAQELLVY 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 KP G KIE + G R + C + Sbjct: 237 GN-KDKPCPKCGGKIESLIIGQRNSFFCPK 265
>FPG_CORJK (Q4JUY8) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 287 Score = 63.5 bits (153), Expect = 5e-10 Identities = 54/186 (29%), Positives = 80/186 (43%), Gaps = 27/186 (14%) Frame = +2 Query: 122 LDDGLEFSFTDKRRFARVRL-------------FDDPETVPP--ISELGPDALFEPMSVD 256 L DG E F D+R F RL P+ P +S + D L Sbjct: 99 LSDGRELCFVDQRTFGEWRLEKAVPDPWAAGAGVASPKNFLPQNVSHIAADPLEAVFDAQ 158 Query: 257 NFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQS 436 V + K+ +K +LL+Q +SGIGN ADE L+ + P + A+ L+R + + QS Sbjct: 159 AAVARMKSKRAAVKTVLLNQEVVSGIGNIYADEALFLAGVRPRRSAALLSRPTLHRVLQS 218 Query: 437 IQEVVKYA------------VDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGR 580 EV++ A V+V+ F + R G +P K G I+ + GGR Sbjct: 219 AAEVMECALEQGGTSFDSLYVNVNGASGYFSRSLNVYGR-GGEPCKRCGAPIKRVVVGGR 277 Query: 581 TTALCA 598 +T CA Sbjct: 278 STHYCA 283
>FPG_NEIG1 (Q5F8Z9) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 63.5 bits (153), Expect = 5e-10 Identities = 39/155 (25%), Positives = 76/155 (49%), Gaps = 1/155 (0%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I + + R P ++ + DG + D R+F + + Sbjct: 71 HLGMSGSLRIFTPSDGRIGR---------PDRHDHVDIVFSDGTVMRYRDPRKFGAILWY 121 Query: 185 DDPETVPPISE-LGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 + E P+ E LGP+ L E D L +K +K L+D + + G+GN A+E L Sbjct: 122 EGIEERHPLLEKLGPEPLSEAFCTDYLYAGLKAQKRAVKLALMDNTVVVGVGNIYANESL 181 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 +++ P + A+ L ++ C L ++++ V++ A++ Sbjct: 182 FRAGISPHRPANRLKKKECAVLVETVKAVLQRAIE 216
>FPG_MIMIV (Q5UQ00) Probable formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase) (EC 4.2.99.18) (AP lyase) Length = 286 Score = 63.2 bits (152), Expect = 7e-10 Identities = 43/126 (34%), Positives = 69/126 (54%), Gaps = 2/126 (1%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFD-DPETVPPISELGPDALFEPMSVDNFVDS 271 +KY++ + D+ L F+D R F + + + E ++ELGPD L + D + Sbjct: 92 AKYTRAVLSFDNELMAYFSDMRNFGTFKFSNSEKELKRKLNELGPDFL---KNDDIDISK 148 Query: 272 LSKKKIGIKALLLDQSFI-SGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 + K K I ALL+DQ I SG+GN++ E+LY++K P ++ S+LT + E L I+ Sbjct: 149 IKKYKQPIVALLMDQKKIGSGLGNYLVAEILYRAKIDPHKLGSNLTDQEIENLWYWIKYE 208 Query: 449 VKYAVD 466 K A D Sbjct: 209 TKLAYD 214
>FPG_MYCPU (Q98QQ1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 277 Score = 63.2 bits (152), Expect = 7e-10 Identities = 36/126 (28%), Positives = 69/126 (54%), Gaps = 2/126 (1%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFA--RVRLFDDPETVPPISELGPDALFEPMSVDNFVDS 271 K+ + ++G E + + R F +R ++ + P++++ + + F + Sbjct: 92 KHIQAIFYFENGSELHYRESRPFGTFHIRYLNNYLKIDPLAKVAQSP--GEIDFETFYNR 149 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 LSKK + IK LLDQS +SGIGN ADE+L+ SK HP ++ L+++ ++E++ Sbjct: 150 LSKKALAIKPTLLDQSIVSGIGNIYADEILFASKIHPATPSNLLSKD-------KVKEIL 202 Query: 452 KYAVDV 469 K A+++ Sbjct: 203 KNAIEI 208
>FPG_PELCD (Q3A3F2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 63.2 bits (152), Expect = 7e-10 Identities = 51/211 (24%), Positives = 90/211 (42%), Gaps = 12/211 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I +D P+ + + L+ G D RRF V Sbjct: 71 HLGMSGSLRIV-------------PSDTPPAAHDHVDIALESGRTLRLNDPRRFGAVLWI 117 Query: 185 DD-PETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 + PE ++ LGP+ + +K+ +K ++DQ + G+GN A E L Sbjct: 118 EGRPEDHALLAHLGPEPFAVEFTGAMLYARSRGRKLAVKNFIMDQRIVVGVGNIYASEAL 177 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCDR-----------FPVEWLF 508 Y++ HP++ A ++R AL +++++V+ A++ R F L Sbjct: 178 YRAGIHPMRAAGRVSRRRYAALAEAVRQVLTAAIEAGGTTLRDFTDENGRPGYFSQRLLV 237 Query: 509 HHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 + R G +P G+ I T G R++ C R Sbjct: 238 YGREG-QPCVHCGRPIRCETIGQRSSYFCTR 267
>FPG_NEIMB (P55044) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 63.2 bits (152), Expect = 7e-10 Identities = 51/209 (24%), Positives = 92/209 (44%), Gaps = 12/209 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I + + R P ++ + DG + D R+F + + Sbjct: 71 HLGMSGSLRIFTPSDGRIGR---------PDRHDHVDIVFSDGTVMRYRDPRKFGAILWY 121 Query: 185 DDPETVPPISE-LGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 + E P+ E LGP+ L E D L +K +K L+D + + G+GN A+E L Sbjct: 122 EGIEEHHPLLEKLGPEPLSEAFCADYLYARLKAQKRAVKLALMDNAVVVGVGNIYANESL 181 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYA-----------VDVDADCDRFPVEWLF 508 +++ P + A+ L ++ C L ++++ V++ A VD D F E+ Sbjct: 182 FRAGISPHRPANRLKKKECALLVETVKAVLQRAIETGGSTLRDFVDSDGKSGYFQQEYTV 241 Query: 509 HHRWGKKPGKVDGKKIEFITAGGRTTALC 595 + R + + G ++ T G R T C Sbjct: 242 YGRHNQPCPRCGGLVVK-ETLGQRGTFYC 269
>FPG_MYCGE (P55825) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 283 Score = 63.2 bits (152), Expect = 7e-10 Identities = 34/113 (30%), Positives = 57/113 (50%) Frame = +2 Query: 125 DDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKAL 304 DDG + ++ D R+F L++ E +++L D L K +K Sbjct: 101 DDGSQLNYHDTRQFGTFHLYEKLEQAAQLNKLAFDPLEAGFDYRKIFQKAQNSKRKVKTF 160 Query: 305 LLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 +LDQ+ ISGIGN ADE+L+ SK +P + LT + E L ++ +++ A+ Sbjct: 161 ILDQTVISGIGNIYADEILFASKINPETMVDQLTIKEIEILCKNATKILAKAI 213
>FPG_LACLC (P42371) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 62.4 bits (150), Expect = 1e-09 Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 13/194 (6%) Frame = +2 Query: 53 KYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPI--SELGP 226 KY+ + +++ + K+ ++ DG + + D R+F L + +P ++GP Sbjct: 78 KYRLATLDAPRE---KHDHLTMKFADG-QLIYADVRKFGTWELISTDQVLPYFLKKKIGP 133 Query: 227 DALF-EPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSL 403 + + E F + L K IK LL+Q+ ++G+GN DEVL+ +K HP + + L Sbjct: 134 EPTYDEDFDEKLFREKLRKSTKKIKPYLLEQTLVAGLGNIYVDEVLWLAKIHPEKETNQL 193 Query: 404 TRESCEALHQSIQEVVKYAVDVDADCDR----------FPVEWLFHHRWGKKPGKVDGKK 553 S LH SI E+++ A+ + R E + + G+K + G + Sbjct: 194 IESSIHLLHDSIIEILQKAIKLGGSSIRTYSALGSTGKMQNELQVYGKTGEKCSRC-GAE 252 Query: 554 IEFITAGGRTTALC 595 I+ I GR T C Sbjct: 253 IQKIKVAGRGTHFC 266
>FPG_MYCPN (P75402) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 276 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/116 (31%), Positives = 62/116 (53%), Gaps = 2/116 (1%) Frame = +2 Query: 128 DGLEFSFTDKRRFARVRLFD--DPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKA 301 DG + ++ D R+F LF+ E +++L D L + + + K IK Sbjct: 102 DGDQLNYHDTRQFGTFHLFNRYQFENARELNKLALDPLDQEFNHQAIFNKGHKSNKKIKT 161 Query: 302 LLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDV 469 +LDQ+ ISGIGN ADE+L+ SK HP +A +L + + Q+ +++K AV++ Sbjct: 162 FILDQTNISGIGNIYADEILFASKIHPETLAKNLNLSQYQLICQNATDILKKAVEM 217
>FPG_GLUOX (Q5FN17) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 276 Score = 62.4 bits (150), Expect = 1e-09 Identities = 57/212 (26%), Positives = 95/212 (44%), Gaps = 15/212 (7%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + I R+ N+ P + +E D G D RRF V L Sbjct: 72 HLGMSGRLTIG--------RAGTNAT---PPAHEHLVLETDSGARAGLVDPRRFGMVDLV 120 Query: 185 --DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEV 358 + ++ ++ LG + L + M+ + ++ IK+ LLDQ I+G+GN E Sbjct: 121 RTSEEDSHRLLAHLGMEPLSDAMTGPALAELFRGRRSPIKSALLDQKLIAGLGNIYVCEA 180 Query: 359 LYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD---------VDADCDRFPVEWLFH 511 L++ HP + A +LT E AL ++I ++++ A+ V AD + + L H Sbjct: 181 LFRCGIHPERQACTLTGEETAALAEAIPQILEQAIASGGSSLRDYVQADGTKGAFQDL-H 239 Query: 512 HRWGKK----PGKVDGKKIEFITAGGRTTALC 595 +G++ P I+ IT GR+T C Sbjct: 240 LVYGREGVPCPNCGAEHPIQRITQAGRSTFFC 271
>FPG_HAEDU (Q7VN67) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 62.0 bits (149), Expect = 1e-09 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 3/156 (1%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKF-FVEL--DDGLEFSFTDKRRFARV 175 H GM+G++ + +NS+ P+K SK V+L + G+ + D R+F Sbjct: 70 HLGMSGSLTL------------LNSSQ--PTKASKHDHVDLITEAGIILRYNDPRKFGAW 115 Query: 176 RLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADE 355 E P I++LGP+ L + + D K + +K +++ + G+GN A E Sbjct: 116 LWAKQAENYPLITKLGPEPLSDTFTSDYLFKKSRNKTVAVKNFIMNNDIVVGVGNIYASE 175 Query: 356 VLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 L+ + HP A +LT + C L IQ V+ A+ Sbjct: 176 SLFMAGVHPELAAQNLTEKQCVQLRNVIQAVLTKAI 211
>FPG_STRT2 (Q5M576) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 62.0 bits (149), Expect = 1e-09 Identities = 45/173 (26%), Positives = 76/173 (43%), Gaps = 2/173 (1%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFD--DPETVPPISELGPDALFEPMSVDNFVD 268 +K+ F +LDDG + D R+F L D E +LGP+ + F Sbjct: 88 NKHFHLFFKLDDGSTLVYQDVRKFGTFDLLDRKQEEAYFTRKKLGPEPTKKTFKYVPFER 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 +L IK LLL+Q ++G+GN DEVL+ +K HP A+ L++ + + +H + Sbjct: 148 ALMHSGKSIKPLLLEQKLVAGLGNIYVDEVLWAAKVHPETPANKLSKAAMKRVHDQTIAI 207 Query: 449 VKYAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCARTA 607 ++ + R + + G+ DG ++ G+T C R A Sbjct: 208 LQLGIAKGGSTIR-----TYRNALGE-----DGTMQNYLQVYGKTGQPCPRCA 250
>FPG_RICCN (Q92GT4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 272 Score = 62.0 bits (149), Expect = 1e-09 Identities = 39/135 (28%), Positives = 71/135 (52%), Gaps = 1/135 (0%) Frame = +2 Query: 62 RSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFD-DPETVPPISELGPDALF 238 R + SA+ K+ +L +G + F D RRF + F D +++LG + Sbjct: 78 RFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFLNDLGIEPFS 137 Query: 239 EPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESC 418 + ++++ D L KKI IK L++D I G+GN A E L+ ++ HP + ++L + Sbjct: 138 DLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGNNLRDDEI 197 Query: 419 EALHQSIQEVVKYAV 463 E L ++I++V+ A+ Sbjct: 198 ENLIKAIRDVLTKAI 212
>FPG_PROMA (Q7VDK6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 282 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 4/126 (3%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARV----RLFDDPETVPPISELGPDALFEPMSVDNFV 265 K+++ + DG E F D R F ++ F E + + +LGP+ + + Sbjct: 98 KHTRVRIWNKDGAEIRFVDTRNFGQMWWISPTFLPTEKITGLKKLGPEPFSKEFNPFYLQ 157 Query: 266 DSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 +SL K+K IK+ LLDQS ++G GN ADE L+Q+ P + + L + + + S+ Sbjct: 158 ESLKKRKRSIKSSLLDQSIVAGAGNIYADESLFQAGILPTKESKKLNKTEIKKICTSLTH 217 Query: 446 VVKYAV 463 ++K ++ Sbjct: 218 ILKISI 223
>FPG_SYNP6 (Q08079) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 281 Score = 62.0 bits (149), Expect = 1e-09 Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 22/178 (12%) Frame = +2 Query: 134 LEFSFTDKRRFARVRLFDDPETVPP----------ISELGPDALFEPMSVDNFVDSLSKK 283 L F + RF +R F VPP +S+LGP+ + D L + Sbjct: 101 LRFEGDRELRFIDIRSFGQMWWVPPDRPVESVITGLSKLGPEPFAPEFTARYLRDRLRRS 160 Query: 284 KIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 + IK LLDQS ++GIGN ADE L+++ HP + LT+ E L ++I EV+ ++ Sbjct: 161 QRPIKTALLDQSLVAGIGNIYADESLFRTGIHPTTPSDRLTKIQAEKLREAIVEVLTASI 220 Query: 464 DVDADC-----DRFPVE-------WLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 D V W++ + +P + G I+ + GR++ C R Sbjct: 221 GAGGTTFSDFRDLTGVNGNYGGQAWVYGRK--DQPCRTCGTPIQKLKLAGRSSHFCPR 276
>FPG_MYCTU (P64150) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 288 Score = 62.0 bits (149), Expect = 1e-09 Identities = 42/119 (35%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = +2 Query: 122 LDDGLEFSFTDKRRFARVRLFD----DPETVP-PISELGPDALFEPMSVDNFVDSLSKKK 286 LDDG SF D+R F L D D VP P++ L D L D V L +K Sbjct: 106 LDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKH 165 Query: 287 IGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 +K LLDQ +SGIGN ADE L+++K + +A++L A+ + +V++ A+ Sbjct: 166 SELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREAL 224
>FPG_MYCBO (P64151) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 288 Score = 62.0 bits (149), Expect = 1e-09 Identities = 42/119 (35%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = +2 Query: 122 LDDGLEFSFTDKRRFARVRLFD----DPETVP-PISELGPDALFEPMSVDNFVDSLSKKK 286 LDDG SF D+R F L D D VP P++ L D L D V L +K Sbjct: 106 LDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKH 165 Query: 287 IGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 +K LLDQ +SGIGN ADE L+++K + +A++L A+ + +V++ A+ Sbjct: 166 SELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREAL 224
>FPG_SHEON (Q8E8D9) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 61.6 bits (148), Expect = 2e-09 Identities = 48/179 (26%), Positives = 78/179 (43%), Gaps = 12/179 (6%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE-LGPDALFEPMSVDNFVDSL 274 K+ + L +G F D RRF PE P+ E LGP+ L + +V+ SL Sbjct: 88 KHDHIDLVLANGRILRFNDPRRFGAWLWCQLPEEAHPLLEKLGPEPLTDAFNVNQLAASL 147 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 + KK IK L+D + G+GN A+E L+ + HP A + E L +++++ Sbjct: 148 AGKKKAIKLCLMDNHIVVGVGNIYANEALFAAGIHPEAEAGKIDIERLTVLVAEVKQILA 207 Query: 455 YAV-----------DVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCA 598 +A+ + D F + + R G+ + G + I G RTT C+ Sbjct: 208 HAIKQGGTTLKDFTNADGKPGYFAQKLHVYGRGGETCTQC-GNLLSEIRLGQRTTVFCS 265
>FPG_STRP6 (Q5XDE4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/181 (25%), Positives = 77/181 (42%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ F EL +G + D R+F L + ++ LGP+ E + F Sbjct: 88 NKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEA 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 L K IK LLDQ+ ++G+GN DEVL+ +K HP +S L + + LH + Sbjct: 148 VLLSSKKTIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRI 207 Query: 449 VKYAVDVDAD----------CDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCA 598 + ++ D ++L + KP G+ I + GGR T +C Sbjct: 208 LALGIEKGGSTVRTYRNTLGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICP 267 Query: 599 R 601 + Sbjct: 268 K 268
>FPG_NEIMA (P57014) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/155 (25%), Positives = 76/155 (49%), Gaps = 1/155 (0%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I + + RS ++ + DG + D R+F + + Sbjct: 71 HLGMSGSLRIFTPSDGRIGRS---------DRHDHVDIVFSDGTVMRYRDPRKFGAILWY 121 Query: 185 DDPETVPPISE-LGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 + E P+ E LGP+ L E D L +K +K L+D + + G+GN A+E L Sbjct: 122 EGIEEHHPLLEKLGPEPLSEAFCTDYLYVRLKAQKRAVKLALMDNAVVVGVGNIYANESL 181 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 +++ P + A+ L ++ C L ++++ V++ A++ Sbjct: 182 FRAGISPHRPANRLKKKECALLVETVKAVLRRAIE 216
>FPG_GLOVI (Q7NFW7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 283 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/183 (25%), Positives = 79/183 (43%), Gaps = 18/183 (9%) Frame = +2 Query: 101 YSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPP------ISELGPDALFEPMSVDNF 262 +++ + + G E F D R F R+ L P VPP ++ LGP+ E Sbjct: 94 HTRVRIPMASGHELRFEDMRVFGRLWLI--PVGVPPERVMGGLTRLGPEPFAEMFDGPYL 151 Query: 263 VDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQ 442 + + +K+ LLDQ ++G+GN ADE L+ S HP L + E LH+++ Sbjct: 152 AGRFAGRNQPVKSALLDQQLVAGVGNIYADEALFSSGIHPALPVGGLDAAALERLHRAVV 211 Query: 443 EVVK------------YAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTT 586 +V++ Y + + W++ + +P +V IE I GR+T Sbjct: 212 KVLEAGIAQRGATLRNYTDAQGINGNYAGTAWVYGRK--GQPCRVCNTPIERIRLAGRST 269 Query: 587 ALC 595 C Sbjct: 270 HFC 272
>FPG_MYCLE (O69470) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 281 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/115 (34%), Positives = 60/115 (52%), Gaps = 5/115 (4%) Frame = +2 Query: 125 DDGLEFSFTDKRRFARVRLFD----DPETVP-PISELGPDALFEPMSVDNFVDSLSKKKI 289 DDG +FTD+R L D D +P P++ L D V+ V L K Sbjct: 100 DDGTVLNFTDQRTLGGWLLADLMTVDGSVLPVPVAHLARDPFDPRFDVEAVVKVLRCKHS 159 Query: 290 GIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 +K LLDQ +SGIGN ADE L++++ H +IA++LTR A+ + +V++ Sbjct: 160 ELKRQLLDQQTVSGIGNIYADEALWRAEVHGARIAATLTRRQLAAVLDAAADVMR 214
>FPG_IDILO (Q5QZC1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/211 (22%), Positives = 91/211 (43%), Gaps = 12/211 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + + T YK ++ +E D+G D RRF + Sbjct: 70 HLGMSGKLRVVPAETTHYKHDHID-------------IEFDNGQTLRLNDPRRFGALLYS 116 Query: 185 D-DPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 + D +S+LGP+ L + ++D + + +K L+D + G+GN A+E L Sbjct: 117 ESDVSGHELLSQLGPEPLTDAFNIDYLFERSRGRSQSVKTFLMDNKVVVGVGNIYANEAL 176 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLF 508 +++ +P + A +++ + L I+E + A++ VD + F + Sbjct: 177 FKAGINPKRAAGKISKVRYQKLVPIIKETLASAIELGGTTLKDFTQVDGNPGYFAQKLQV 236 Query: 509 HHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 + R GK V +++ + G R+T C + Sbjct: 237 YGRGGKL-CMVCSNRLKEVRLGQRSTVYCTQ 266
>FPG_BDEBA (Q6ML45) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/178 (23%), Positives = 75/178 (42%), Gaps = 11/178 (6%) Frame = +2 Query: 101 YSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSK 280 + ++ L ++ D RRF DP P +++LGP+ L + + L Sbjct: 90 HDHIYLHFSGDLRLAYRDPRRFGCFDFVQDPLKHPKLADLGPEPLEAEFNGPLLWEKLRG 149 Query: 281 KKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYA 460 K + +K L+DQ + G+GN A E L+ + P A L+ E L I++++ + Sbjct: 150 KDVALKVALMDQKVVVGVGNIYASEALFAAGIKPTLPARKLSLERASLLVGEIKKILSQS 209 Query: 461 V-----------DVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 + + F + + R K+P G++++ GGR T C+R Sbjct: 210 IKAGGSSISDFAQASGESGYFQTSFRVYGR-DKEPCVTCGQQVKSKVLGGRNTFWCSR 266
>FPG_STRP8 (Q8P250) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 61.2 bits (147), Expect = 2e-09 Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ F EL +G + D R+F L + ++ LGP+ E + F Sbjct: 88 NKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEA 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 +L + IK LLDQ+ ++G+GN DEVL+ +K HP +S L + + LH + Sbjct: 148 ALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRI 207 Query: 449 VKYAVDVDAD----------CDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCA 598 + ++ D ++L + KP G+ I + GGR T +C Sbjct: 208 LALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICP 267 Query: 599 R 601 + Sbjct: 268 K 268
>FPG_STRP1 (Q9A131) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 61.2 bits (147), Expect = 2e-09 Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ F EL +G + D R+F L + ++ LGP+ E + F Sbjct: 88 NKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEA 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 +L + IK LLDQ+ ++G+GN DEVL+ +K HP +S L + + LH + Sbjct: 148 ALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRI 207 Query: 449 VKYAVDVDAD----------CDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCA 598 + ++ D ++L + KP G+ I + GGR T +C Sbjct: 208 LALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICP 267 Query: 599 R 601 + Sbjct: 268 K 268
>FPG_MYCMO (Q6KHS0) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 273 Score = 60.8 bits (146), Expect = 3e-09 Identities = 47/179 (26%), Positives = 77/179 (43%), Gaps = 12/179 (6%) Frame = +2 Query: 101 YSKFFVELDDGLEFSFTDKRRFA--RVRLFDDPETVPPISELGPDALFEPMSVDNFVDSL 274 + + DG + D R F R ++ + P+S + P + +D F L Sbjct: 92 HDRLIFHFTDGSSLHYHDSRMFGTFHFRNSENYLKIKPLSLVAPVPW--KIDLDEFFKLL 149 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 +KK IK +LLDQ I+G+GN DE L+ SK HP A+ L+ E + + ++ +++ Sbjct: 150 KRKKTAIKKILLDQQIIAGLGNIYVDETLFASKVHPEFKANQLSLEQVKLILKNATRILQ 209 Query: 455 YAVDVDADCDRFPV----------EWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 + + R +L H KP G+ I+ I GGR T C + Sbjct: 210 ESTKLGGSSIRSYTSLNEKEGSFQNFLQVHTKFNKPCPNCGELIQKIKLGGRGTYFCKK 268
>FPG_STRCO (Q9ZBQ6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 285 Score = 60.8 bits (146), Expect = 3e-09 Identities = 49/162 (30%), Positives = 77/162 (47%), Gaps = 7/162 (4%) Frame = +2 Query: 5 HEGMAGAIYIKG--VAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVR 178 H GM+G + ++ K+ R V AD G E F D+R F + Sbjct: 76 HLGMSGQLLVQPHETPAEKHLRIRVRFADAL-------------GTELRFVDQRTFGGLS 122 Query: 179 LFDD-----PETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNW 343 L D P+ + I+ D LF+ + F +L +K+ IK LLDQS ISG+GN Sbjct: 123 LHDTSADGLPDVIAHIARDPLDPLFDD---EAFHHALRRKRTTIKRALLDQSLISGVGNI 179 Query: 344 IADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDV 469 ADE L++++ H + ++LTR L +++V+ A+ V Sbjct: 180 YADEALWRARLHYERPTATLTRPRTTELLGHVRDVMNAALAV 221
>FPG_STRPM (Q48UU6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 60.8 bits (146), Expect = 3e-09 Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 12/181 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ F EL +G + D R+F L + ++ LGP+ E + F Sbjct: 88 NKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEA 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 +L + IK LLDQ+ ++G+GN DEVL+ +K HP +S L + + LH + Sbjct: 148 ALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPGTASSRLNKAEIKRLHDETIRI 207 Query: 449 VKYAVDVDAD----------CDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCA 598 + ++ D ++L + KP G+ I + GGR T +C Sbjct: 208 LALGIEKGGSTVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICP 267 Query: 599 R 601 + Sbjct: 268 K 268
>FPG_STRP3 (Q8K8D0) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 274 Score = 60.8 bits (146), Expect = 3e-09 Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 2/175 (1%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISE--LGPDALFEPMSVDNFVD 268 +K+ F EL +G + D R+F L + ++ LGP+ E + F Sbjct: 88 NKHFHVFFELKNGSTLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEA 147 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 +L + IK LLDQ+ ++G+GN DEVL+ +K HP +S L + + LH + Sbjct: 148 ALLSSQKPIKPHLLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRI 207 Query: 449 VKYAVDVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCARTAEA 613 + ++ R + + G DG +++ G+T C R +A Sbjct: 208 LALGIEKGGSTVR-----TYRNALG-----ADGTMQDYLQVYGQTGKSCPRCGQA 252
>FPG_THIDA (Q3SLR9) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 60.8 bits (146), Expect = 3e-09 Identities = 42/153 (27%), Positives = 67/153 (43%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ + A + V DW DDG D RRF V L Sbjct: 71 HLGMSGSLRLTEPAEPAARHDHV----DW---------RFDDGTILRLRDPRRFGAVLLT 117 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 ++ P ++ LGP+ L ++K IK L++D + G+GN A E L+ Sbjct: 118 ENAPGHPLLAGLGPEPLSTAFDAAYLHTQCQRRKTAIKPLIMDAHVVVGVGNIYASESLF 177 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 + P A L+R +C L +I++V+ A+ Sbjct: 178 HAGIRPGVAAHRLSRAACARLADAIKQVLTAAI 210
>FPG_PSEPK (Q88CQ5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 60.8 bits (146), Expect = 3e-09 Identities = 45/180 (25%), Positives = 78/180 (43%), Gaps = 11/180 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSL 274 +K+ +EL+ GL +TD RRF + DP + LGP+ L + + Sbjct: 88 AKHEHVDIELESGLMLRYTDPRRFGAMLWSLDPLNHELLLRLGPEPLTDLFDGERLFQLS 147 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 + + +K ++D + + G+GN A E L+ + P + A ++R L I+ V+ Sbjct: 148 RGRSMAVKPFIMDNAVVVGVGNIYATEALFAAGIDPRREAGGISRARYLKLAIEIKRVLA 207 Query: 455 YAVDV-----------DADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 A++ D F E LF + G +P KV G ++ + G R + C R Sbjct: 208 AAIEQGGTTLRDFIGGDGQPGYFQQE-LFVYGRGGQPCKVCGTELREVKLGQRASVYCPR 266
>FPG_VIBPA (Q87T81) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 60.1 bits (144), Expect = 6e-09 Identities = 47/208 (22%), Positives = 90/208 (43%), Gaps = 11/208 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V AD +K+ ++L +G + D RRF Sbjct: 70 HLGMSGSL-------------RVLDADFPAAKHDHVDLKLTNGKVLRYNDPRRFGAWLWC 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 E+ + +GP+ L + + + D K++ +K ++D + G+GN A+E L+ Sbjct: 117 APGESHAVLEHMGPEPLTDAFNSEYIADKAQGKRVAVKQFIMDNKVVVGVGNIYANESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLFH 511 +S+ P + A +T + L ++I+ +K A++ D F E L + Sbjct: 177 KSRILPTRQAGQVTPQEWVLLVENIKATLKIAINQGGTTLKDFAQADGKPGYFAQELLVY 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALC 595 + G +P G+ ++ + G R T C Sbjct: 237 GKAG-EPCPECGEPLQELKIGQRNTFFC 263
>FPG_THEFY (Q47S77) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 295 Score = 59.7 bits (143), Expect = 7e-09 Identities = 41/115 (35%), Positives = 57/115 (49%), Gaps = 6/115 (5%) Frame = +2 Query: 137 EFSFTDKRRFARV---RLFDDPETV---PPISELGPDALFEPMSVDNFVDSLSKKKIGIK 298 E F D+R F + RL DD IS + D L D F +L +K+ +K Sbjct: 114 ELRFVDQRTFGHLLVDRLVDDGTGTGLPSVISHIARDPLDPAFDEDAFAAALCRKRTELK 173 Query: 299 ALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 LLDQS ISGIGN ADE L+ S+ H +L+R L +++EV+ A+ Sbjct: 174 RALLDQSLISGIGNIYADEALWMSQLHWATPTEALSRSQVATLLAAVREVMVAAL 228
>FPG_STRAW (Q82JU0) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 285 Score = 59.3 bits (142), Expect = 9e-09 Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 5/118 (4%) Frame = +2 Query: 131 GLEFSFTDKRRFARVRLFDD-----PETVPPISELGPDALFEPMSVDNFVDSLSKKKIGI 295 G E F D+R F + L D P+ + I+ D LF+ + F ++L +K+ + Sbjct: 107 GTELRFVDQRTFGGLSLHDTTPDGLPDVIAHIARDPLDPLFDDAA---FHEALRRKRTTV 163 Query: 296 KALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDV 469 K LLDQS ISG+GN ADE L++++ H + + TR L +++V+ A+ V Sbjct: 164 KRALLDQSLISGVGNIYADEALWRARIHYERPTAGFTRPRTAELLGHVRDVMNAALAV 221
>FPG_SILPO (Q5LWT9) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 282 Score = 59.3 bits (142), Expect = 9e-09 Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 17/216 (7%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPS--KYSKFFVELDDGLEFSFTDKRRFARVR 178 H GM+G + + G + ++ D P+ K+ +D+G +F D RRF + Sbjct: 72 HLGMSGRMTVSGDPLGQF-------VHDHPAAQKHDHVVFHMDNGARITFNDPRRFGAMD 124 Query: 179 LFDDP--ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIAD 352 L + + LGP+ L D V +L + +K+ LLDQ ++G+GN Sbjct: 125 LMATATADEHKLLMVLGPEPLGNDFHEDYLVAALKGRNTPVKSALLDQGIVAGLGNIYVC 184 Query: 353 EVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVE 499 E L+++ P + A + AL I++V+ A++ D + F Sbjct: 185 EALFRAGVSPRRKAGQIAAARVSALVPIIRQVLSEAIEAGGSSLKDFRQADGELGYFQHS 244 Query: 500 WLFHHRWGK--KPGKVDGKKIEFITAGGRTTALCAR 601 + + R G+ + DG ++ IT GR++ CA+ Sbjct: 245 FDVYGREGEPCRRAGCDG-TVQRITQSGRSSFYCAQ 279
>FPG_XANOR (Q5H667) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 57.8 bits (138), Expect = 3e-08 Identities = 49/208 (23%), Positives = 86/208 (41%), Gaps = 11/208 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V D P + + L +G F D RRF + Sbjct: 72 HLGMSGSL-------------RVLPGDTLPRAHDHVDISLQNGRVLRFNDPRRFGCLLWQ 118 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 D + ++ LGP+ L E + D ++ +K L+DQ+ + G+GN A E L+ Sbjct: 119 SDIQAHELLAALGPEPLSEAFTGDYLHALAYGRRAPVKTFLMDQAVVVGVGNIYAAESLH 178 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYA-----------VDVDADCDRFPVEWLFH 511 + PL+ A ++ + L ++++++ YA + D F E + Sbjct: 179 CAGISPLREAGKVSLDRYRRLAAAVKDILSYAIRRGGTTLRDFISPDGAPGYFEQELTVY 238 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALC 595 R G +P K G+ ++ G R T C Sbjct: 239 GREG-EPCKQCGRVLKHAMIGQRATVWC 265
>FPG_XANAC (Q8PEQ4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 57.8 bits (138), Expect = 3e-08 Identities = 48/208 (23%), Positives = 85/208 (40%), Gaps = 11/208 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V D P + + L G F D RRF + Sbjct: 72 HLGMSGSL-------------RVLPGDTLPRAHDHVDISLQSGRLLRFNDPRRFGCLLWQ 118 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 + ++ LGP+ L + + D ++ +K L+DQ+ + G+GN A E L+ Sbjct: 119 SGTQAHDLLAALGPEPLSDAFTGDYLHALAQGRRAAVKTFLMDQAVVVGVGNIYAAESLH 178 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYA-----------VDVDADCDRFPVEWLFH 511 ++ PL+ A ++ E L ++++++ YA + D F E + Sbjct: 179 RAGISPLREAGKVSLERYRRLADAVKDILAYAIQRGGTTLRDFISPDGAPGYFEQELFVY 238 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALC 595 R G + K G+ ++ T G R T C Sbjct: 239 GREG-EACKQCGRVLKHATIGQRATVWC 265
>FPG_BARQU (Q6G0L3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 290 Score = 57.8 bits (138), Expect = 3e-08 Identities = 59/222 (26%), Positives = 99/222 (44%), Gaps = 23/222 (10%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELD--DGLEFSFT--DKRRFAR 172 H GM+G+ I+ + K +A K+ F +++ DG + T D RRF Sbjct: 72 HLGMSGSWRIEDDLLRKTYSAAGKFV-----KHDHFLMDIQAKDGKVYHLTYNDVRRFGF 126 Query: 173 VRLFDDPETV--PPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWI 346 + L D P + +LG + L S ++ KKI +K +LLDQS I+G+GN Sbjct: 127 MLLLDTNRIYEHPLLKKLGLEPLSNEFSGRYLQEAFVNKKISLKGVLLDQSIIAGLGNIY 186 Query: 347 ADEVLYQSKTHP------LQIASSLTRESCEALHQSIQEVVKYAVD-----------VDA 475 E L++S+ P L + + RE ++L Q+I+ V+ A+ D Sbjct: 187 VCEALWRSRLSPQRGAFTLALKTVCAREFADSLAQNIRNVIAEAISFGGSTLRDYIRTDG 246 Query: 476 DCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 F + + R GK+ + G I I+ GR++ C++ Sbjct: 247 SLGYFQHSFSVYGREGKECFQC-GIPITRISQSGRSSFYCSQ 287
>FPG_PSEF5 (Q4K4A5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 57.8 bits (138), Expect = 3e-08 Identities = 50/210 (23%), Positives = 85/210 (40%), Gaps = 11/210 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + + V + K V+ +EL+ GL +TD RRF + Sbjct: 71 HLGMSGNLRLVEVGLPAAKHEHVD-------------IELESGLALRYTDPRRFGAMLWS 117 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 DP + LGP+ L + + + + +K ++D + + G+GN A E L+ Sbjct: 118 HDPLNHELLVRLGPEPLTDLFDGERLYQLSRGRSMAVKPFIMDNAVVVGVGNIYATEALF 177 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLFH 511 + P + A ++R L I+ ++ A++ D F E LF Sbjct: 178 AAGIDPRREAKGISRARYLKLAIEIKRILAAAIERGGTTLRDFIGGDGQPGYFQQE-LFV 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 + G + KV G + I G R + C R Sbjct: 237 YGRGGENCKVCGTGLREIKLGQRASVYCPR 266
>FPG_XANC5 (Q3BM92) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 57.4 bits (137), Expect = 4e-08 Identities = 48/208 (23%), Positives = 86/208 (41%), Gaps = 11/208 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V D P + + L +G F D RRF + Sbjct: 72 HLGMSGSL-------------RVLPGDTLPRAHDHVDISLQNGRVLRFNDPRRFGCLLWQ 118 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 +T ++ LGP+ L + + D ++ +K L+DQ+ + G+GN A E L+ Sbjct: 119 SGTQTHELLAALGPEPLSDAFTGDYLHALAQGRRAAVKTFLMDQAVVVGVGNIYAAESLH 178 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYA-----------VDVDADCDRFPVEWLFH 511 ++ PL+ A ++ L ++++++ YA + D F E + Sbjct: 179 RAGISPLREAGKVSLARYRRLADAVKDILAYAIQRGGTTLRDFISPDGAPGYFEQELSVY 238 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALC 595 R G + K G+ ++ T G R T C Sbjct: 239 GREG-EACKQCGRVLKHATIGQRATVWC 265
>FPG_ZYMMO (Q9X3X1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 57.4 bits (137), Expect = 4e-08 Identities = 46/180 (25%), Positives = 82/180 (45%), Gaps = 13/180 (7%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVP--PISELGPDALFEPMSVDNFVDS 271 K+ F ++ + S D RRF + L + + +GP+ L + + Sbjct: 88 KHDHFVLQTKNNFIVSLYDPRRFGSLDLVKKNQLLEWSYFRNIGPEPLTGNFNPEYLQKK 147 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 L IK +LLDQ ++GIGN A E L+Q+K HP + + +L + +L SI+ ++ Sbjct: 148 LFSSSAPIKKILLDQKVVAGIGNIYACEALHQAKIHPQRPSKNLNFDEITSLVFSIKNIL 207 Query: 452 KYAV-----------DVDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCA 598 + A+ + + F ++ + + G++ G IE T GGR+T LC+ Sbjct: 208 QKAIAEGGSTLKDYARPNGELGYFSTKFKVYGKEGEQ--CECGHTIERYTLGGRSTFLCS 265
>FPG_CHRVO (Q7NQS5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 57.4 bits (137), Expect = 4e-08 Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 12/162 (7%) Frame = +2 Query: 146 FTDKRRFARVRLFDDP-ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSF 322 F D RRF V P E P + LGP+ L + ++ ++ IK ++D Sbjct: 104 FRDPRRFGAVLWHLGPVEMHPLLQALGPEPLSDAFDGAALHQAIRRRGSPIKLAIMDNHV 163 Query: 323 ISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCDR----- 487 + G+GN A+E L+ + P + A L+R C+ L I+ V++ A+D R Sbjct: 164 VVGVGNIYANESLFHAGISPARAACDLSRADCDRLAAEIKAVLRRAIDAGGSTLRDFVDS 223 Query: 488 ------FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 F ++ ++R ++P ++ G I I G R+T C Sbjct: 224 EGKPGYFQQTYMVYNR-QEEPCRLCGTPIRQIRQGQRSTYYC 264
>FPG_YERPS (Q66GD3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 57.0 bits (136), Expect = 5e-08 Identities = 53/208 (25%), Positives = 85/208 (40%), Gaps = 11/208 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V S + K+ + + +G +TD RRF Sbjct: 70 HLGMSGSL-------------RVLSEETAAEKHDHVDLVVSNGKILRYTDPRRFGAWLWA 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 D ET ++ LGP+ L + + D K+ IK L+D + G+GN A E L+ Sbjct: 117 KDLETSNVLAHLGPEPLSDEFTAQYLFDKSRNKRTLIKPWLMDNKVVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLFH 511 + P + A SLT L +I+ V+ ++++ D F E + Sbjct: 177 AAGILPDRAAGSLTDAESVLLVATIKAVLLHSIEQGGTTLRDFLQSDGKPGYFAQELQVY 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALC 595 R G +P + G IE G R+T C Sbjct: 237 GRAG-EPCRQCGHPIEIAKHGQRSTFFC 263
>FPG_YERPE (Q8ZJP0) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 57.0 bits (136), Expect = 5e-08 Identities = 53/208 (25%), Positives = 85/208 (40%), Gaps = 11/208 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V S + K+ + + +G +TD RRF Sbjct: 70 HLGMSGSL-------------RVLSEETAAEKHDHVDLVVSNGKILRYTDPRRFGAWLWA 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 D ET ++ LGP+ L + + D K+ IK L+D + G+GN A E L+ Sbjct: 117 KDLETSNVLAHLGPEPLSDEFTAQYLFDKSRNKRTLIKPWLMDNKVVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLFH 511 + P + A SLT L +I+ V+ ++++ D F E + Sbjct: 177 AAGILPDRAAGSLTDAESVLLVATIKAVLLHSIEQGGTTLRDFLQSDGKPGYFAQELQVY 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALC 595 R G +P + G IE G R+T C Sbjct: 237 GRAG-EPCRQCGHPIEIAKHGQRSTFFC 263
>FPG_RHOPA (Q6NDM1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 290 Score = 57.0 bits (136), Expect = 5e-08 Identities = 37/123 (30%), Positives = 61/123 (49%), Gaps = 8/123 (6%) Frame = +2 Query: 119 ELDDGLEFSFTDKRRFARVRLF--DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIG 292 E+ G F D RRF +++F + ET P + LGP+ L + + K+ Sbjct: 109 EMASGARVVFNDPRRFGFMKVFPRSEIETEPHLKGLGPEPLGNAFDASLLAKACAGKQTS 168 Query: 293 IKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCE------ALHQSIQEVVK 454 +KA LLDQ ++G+GN E L+++ P + AS+L E L ++I+EV+ Sbjct: 169 LKAALLDQRVVAGLGNIYVCEALFRAHLSPKRKASTLANRKDEPTDHAVRLTEAIREVLG 228 Query: 455 YAV 463 A+ Sbjct: 229 EAI 231
>FPG_ANASP (Q8YP80) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 282 Score = 57.0 bits (136), Expect = 5e-08 Identities = 41/182 (22%), Positives = 85/182 (46%), Gaps = 16/182 (8%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFDD----PETVPPISELGPDALFEPMSVDNFV 265 K+++ + ++ E F D+R F ++ + +++L D +V+ Sbjct: 98 KHTRVRIFFEEEQELRFVDQRTFGQMWWVPPGIAVESVITGLAKLAVDPFSPEFTVEYLA 157 Query: 266 DSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 + L ++ IK LLDQS ++G+GN ADE L++S P + + + + + L +I + Sbjct: 158 NKLHNRRRPIKTALLDQSVVAGLGNIYADEALFKSGVLPETLCTEVQLKQIKLLRTAIIQ 217 Query: 446 VVKYAVDV------------DADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTA 589 V++ +++ + + V W+++ +P KV G I+ I GGR++ Sbjct: 218 VLETSIEAGGTTFSNFLNVKGVNGNYGGVAWVYNR--AGEPCKVCGDVIQRIKLGGRSSH 275 Query: 590 LC 595 C Sbjct: 276 FC 277
>FPG_PSEPF (Q3K566) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 57.0 bits (136), Expect = 5e-08 Identities = 49/210 (23%), Positives = 86/210 (40%), Gaps = 11/210 (5%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G + + V + K V+ +EL+ GL +TD RRF + Sbjct: 71 HLGMSGNLRLVEVGMPAAKHEHVD-------------IELESGLALRYTDPRRFGAMLWS 117 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 +DP + LGP+ L + + + + +K ++D + + G+GN A E L+ Sbjct: 118 NDPLNHELLIRLGPEPLTDLFDGERLYQLSRGRSMAVKPFIMDNAVVVGVGNIYATEALF 177 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD-----------VDADCDRFPVEWLFH 511 + P + A ++R L I+ ++ A++ D F E LF Sbjct: 178 AAGIDPRREAKGISRARYLKLAIEIKRILAAAIERGGTTLRDFIGGDGQPGYFQQE-LFV 236 Query: 512 HRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 + G + KV G + + G R + C R Sbjct: 237 YGRGGEHCKVCGTGLREMKLGQRASVWCPR 266
>FPG_SYNPX (Q7U4V2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 277 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 10/111 (9%) Frame = +2 Query: 161 RFARVRLFDDPETVPP----------ISELGPDALFEPMSVDNFVDSLSKKKIGIKALLL 310 RF VR F + VPP ++ LGP+ E S L IK LL Sbjct: 108 RFVDVRSFGEMWWVPPDVELTVGIPGLARLGPEPFSEAFSAPYLKRQLKNSSRPIKTALL 167 Query: 311 DQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 DQ+ ++G+GN ADE L+ + PL A LT E L S+ EV+ ++ Sbjct: 168 DQALVAGVGNIYADESLFSAGIPPLTPAGRLTLAQLERLRSSLVEVLTTSI 218
>FPG_PASPI (Q8VW76) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 1/125 (0%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPI-SELGPDALFEPMSVDNFVD 268 P K+ + L G + D RRF L+ +T + ++LGP+ L + + D Sbjct: 86 PEKHDHVDLALSSGEILRYNDPRRFG-AWLWQPVDTKHHVLAKLGPEPLTDVFTADYLQQ 144 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 K+ IK ++D + G+GN A+E L+ + HP + A +T ++ L I+ V Sbjct: 145 KAKGKRTAIKQFIMDNHIVVGVGNIYANESLFSAGIHPQKAAGEVTPQALTVLVDEIKAV 204 Query: 449 VKYAV 463 + +A+ Sbjct: 205 LAFAI 209
>FPG_AGRT5 (Q8UIH4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 297 Score = 55.5 bits (132), Expect = 1e-07 Identities = 59/224 (26%), Positives = 94/224 (41%), Gaps = 26/224 (11%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKR-SAVNSADDWPSKYSKFFVELDDGLE---FSFTDKRRFAR 172 H GM+G+ I+ + A + A K+ LD G E + D RRF Sbjct: 72 HLGMSGSFRIEAEKGEGGEAPGAFHYARSKDGKHDHVVFHLDKGEERVCVIYNDPRRFGF 131 Query: 173 VRLFDDP--ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWI 346 + L + + P +ELGP+ +S D K +K+ LLDQ I+G+GN Sbjct: 132 MHLVERNKLDLYPAFAELGPEPTGNALSADYLASRFEGKSQPLKSTLLDQKIIAGLGNIY 191 Query: 347 ADEVLYQSKTHPLQIASSL--TRESCEA----LHQSIQEVVKYAVDVDADCDRFPVE--- 499 E L+++ PL+ A +L TR +A L + I++V+ A+ R ++ Sbjct: 192 VCEALWRAHLSPLRAAGTLVTTRGKPKAQLIDLTEKIRDVIADAIAAGGSSLRDHIQTDG 251 Query: 500 --WLFHHRWG---------KKPGKVDGKKIEFITAGGRTTALCA 598 F H + + PG G +E + GR+T CA Sbjct: 252 TLGYFQHSFSVYDQEGQPCRTPG--CGGTVERVVQAGRSTFYCA 293
>FPG_VIBVY (Q7MPS3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/154 (22%), Positives = 67/154 (43%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V AD K+ ++L +G + D RRF Sbjct: 70 HLGMSGSL-------------RVLDADFPAGKHDHVDLKLSNGKVLRYNDPRRFGAWLYA 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 E + +GP+ L + + K++ +K ++D + G+GN A E L+ Sbjct: 117 APGEDHDVLGNIGPEPLTDAFDGQYMFEKAQGKRVAVKQFIMDNKIVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 +S+ P + SL+ E + L I++ ++ A++ Sbjct: 177 RSRILPTRATMSLSAEEWQRLVSHIKQTLQTAIE 210
>FPG_PHOPR (Q6LVN0) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 55.1 bits (131), Expect = 2e-07 Identities = 37/155 (23%), Positives = 69/155 (44%), Gaps = 1/155 (0%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ I ++ P K+ + L G + D RRF L+ Sbjct: 70 HLGMSGSLRILPASIP-------------PEKHDHVDLVLSSGEVLRYNDPRRFG-AWLW 115 Query: 185 DDPETVPPI-SELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 P+ + S+LGP+ L + + + K+ IK ++D + G+GN A+E L Sbjct: 116 GLPDLDHKVLSQLGPEPLSNDFTAEYLQERAKGKRTAIKQFIMDNKVVVGVGNIYANESL 175 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 + + HP + A ++ E I+ V+ +A++ Sbjct: 176 FSAGIHPKRAAGEISPEKIALFVDEIKSVLAFAIE 210
>FPG_PSEAE (Q9L7T2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 269 Score = 55.1 bits (131), Expect = 2e-07 Identities = 42/180 (23%), Positives = 77/180 (42%), Gaps = 11/180 (6%) Frame = +2 Query: 95 SKYSKFFVELDDGLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSL 274 S++ +EL G+ +TD RRF + P + LGP+ L + + + Sbjct: 88 SRHEHVDIELASGMALRYTDPRRFGAMLWSLAPLEHELLRNLGPEPLTDAFAGQRLFELS 147 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 + + +K ++D + + G+GN A E L+ + P + A S+++ L + I+ ++ Sbjct: 148 RGRSMAVKPFIMDNAVVVGVGNIYASEALFAAGIDPRKPAGSISKARYLRLAEEIKRILA 207 Query: 455 YAVD-----------VDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 A++ D F E LF + G + KV G + I G R + C R Sbjct: 208 IAIERGGTTLRDFVGGDGQPGYFQQE-LFVYGRGGEFCKVCGSTLREIRLGQRASVYCPR 266
>FPG_VIBVU (Q8DDY4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 268 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/154 (22%), Positives = 66/154 (42%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ V AD K+ ++L +G + D RRF Sbjct: 70 HLGMSGSL-------------RVLDADFPAGKHDHVDLKLSNGKVLRYNDPRRFGAWLYA 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 E + +GP+ L + K++ +K ++D + G+GN A E L+ Sbjct: 117 APGEDHDVLGNIGPEPLTNAFDGQYMFEKAQGKRVAVKQFIMDNKIVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 +S+ P + SL+ E + L I++ ++ A++ Sbjct: 177 RSRILPTRATMSLSAEEWQRLVSHIKQTLQTAIE 210
>FPG_CAUCR (Q9A259) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 286 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 2/126 (1%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLF--DDPETVPPISELGPDALFEPMSVDNFVDS 271 K++ + +DG ++ D RRF + L D + +GP+ L E + Sbjct: 102 KHAHVVFQTEDGATVTYFDPRRFGFMDLIPTDRVSHHAWFAAMGPEPLGEGFDARTLEKA 161 Query: 272 LSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVV 451 + +K G K LLLDQ ++G+GN E L++S P + + ++ ++ L +I++V+ Sbjct: 162 FANRKQGPKTLLLDQRTVAGLGNIYVCEALHRSGISPFKPSGNIAKKRLTPLTAAIKDVL 221 Query: 452 KYAVDV 469 AV+V Sbjct: 222 AEAVEV 227
>FPG_PROMT (Q46H41) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 281 Score = 54.3 bits (129), Expect = 3e-07 Identities = 36/123 (29%), Positives = 60/123 (48%), Gaps = 4/123 (3%) Frame = +2 Query: 107 KFFVELDDGLEFSFTDKRRFARVRLFDD----PETVPPISELGPDALFEPMSVDNFVDSL 274 +FF E G E F D R F ++ PE V I LGP+ + + + L Sbjct: 102 RFFDER--GRELRFIDIRNFGQMWHVPSSRSIPEIVSGIKRLGPEPFSDDFNSHYLEEYL 159 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 KK IK+ LLDQ ++G+GN ADE L+ + +P + + +L + L S+ +++ Sbjct: 160 KKKTRSIKSALLDQETVAGVGNIYADETLFDAGINPKKESRNLKSTELKRLCNSLVKILN 219 Query: 455 YAV 463 ++ Sbjct: 220 ISI 222
>FPG_RHILO (Q98BG6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 295 Score = 53.9 bits (128), Expect = 4e-07 Identities = 51/177 (28%), Positives = 78/177 (44%), Gaps = 21/177 (11%) Frame = +2 Query: 146 FTDKRRFARVRLFD-DPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSF 322 F D RRF + + PET P ++ LG + + L + +KA LLDQ Sbjct: 122 FNDPRRFGFMLFAEGSPETHPMLAGLGVEPTGNTLDGVLLASLLKGRGSPLKAALLDQKL 181 Query: 323 ISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQS------IQEVVKYAV------- 463 I+G+GN E L+++ PL+ A ++ R S +A QS I+ V+ A+ Sbjct: 182 IAGLGNIYVSEALWRAGLSPLREAGTIARPSKKARQQSERLAEAIRSVISDAIAAGGSSL 241 Query: 464 ----DVDADCDRFPVEWLFHHRWGK---KPGKVDGKKIEFITAGGRTTALCARTAEA 613 D F + + R G+ KPG G IE + GR+T C RT ++ Sbjct: 242 RDYMHTDGSLGYFQHSFAVYDREGEPCPKPG--CGGHIERVVQSGRSTFYC-RTCQS 295
>FPG_VIBF1 (Q5E8M1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 271 Score = 53.5 bits (127), Expect = 5e-07 Identities = 35/153 (22%), Positives = 67/153 (43%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM+G++ + V K V+ + L++G + D R+F Sbjct: 70 HLGMSGSLRVLDEEVPSAKHDHVD-------------LVLENGKVLRYNDPRKFGAWLYS 116 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLY 364 + +S+LGP+ L + + F + KK +K +++ + + G+GN A E L+ Sbjct: 117 EVGVAHQVLSKLGPEPLTNEFNSEYFAEKAKNKKTVVKQFIMNNAVVVGVGNIYASESLF 176 Query: 365 QSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 ++ HP SL L I++V++ A+ Sbjct: 177 MAQIHPKTSVGSLKASQITLLVAEIKKVLETAI 209
>FPG_XYLFT (P64155) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 53.5 bits (127), Expect = 5e-07 Identities = 38/160 (23%), Positives = 71/160 (44%), Gaps = 10/160 (6%) Frame = +2 Query: 146 FTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFI 325 F D RRF + +D + P + LG + L + + D + + +K L+DQ + Sbjct: 106 FNDPRRFGCLLWQEDGQIHPLLQRLGCEPLSDSFNGDYLYQCSRARNVSVKTFLMDQRIV 165 Query: 326 SGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCDR------ 487 G+GN A E L+++ PL A ++ + L + +++++ YA++ R Sbjct: 166 VGVGNIYAAESLFRAGISPLCEADKISLQRYRRLAEVVKDILLYAINRGGTTLRDFLSPD 225 Query: 488 ----FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 + + LF + ++P K G + T RTT C Sbjct: 226 GRPGYFKQELFVYGRQQQPCKQCGSLLRQTTIRQRTTVWC 265
>FPG_XYLFA (P64154) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 53.5 bits (127), Expect = 5e-07 Identities = 38/160 (23%), Positives = 71/160 (44%), Gaps = 10/160 (6%) Frame = +2 Query: 146 FTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFI 325 F D RRF + +D + P + LG + L + + D + + +K L+DQ + Sbjct: 106 FNDPRRFGCLLWQEDGQIHPLLQRLGCEPLSDSFNGDYLYQCSRARNVSVKTFLMDQRIV 165 Query: 326 SGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCDR------ 487 G+GN A E L+++ PL A ++ + L + +++++ YA++ R Sbjct: 166 VGVGNIYAAESLFRAGISPLCEADKISLQRYRRLAEVVKDILLYAINRGGTTLRDFLSPD 225 Query: 488 ----FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 + + LF + ++P K G + T RTT C Sbjct: 226 GRPGYFKQELFVYGRQQQPCKQCGSLLRQTTIRQRTTVWC 265
>FPG_BARHE (Q6G4T2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 290 Score = 52.8 bits (125), Expect = 9e-07 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 10/126 (7%) Frame = +2 Query: 116 VELDDGLEFSFT--DKRRFARVRLFDDPETV--PPISELGPDALFEPMSVDNFVDSLSKK 283 ++ DG + T D RRF + L D P + +LG + + S + K Sbjct: 106 IQAKDGKVYHLTYNDVRRFGFMLLVDTRSLYEHPLLKKLGLEPMSNAFSGSYLQEVFVNK 165 Query: 284 KIGIKALLLDQSFISGIGNWIADEVLYQSKTHP------LQIASSLTRESCEALHQSIQE 445 KI +K +LLDQS ++G+GN E L++S+ P L + + RE +L Q+I+ Sbjct: 166 KISLKGVLLDQSIVAGLGNIYVCEALWRSRLSPQRGAFTLALKTECARELAASLAQNIRN 225 Query: 446 VVKYAV 463 V+ A+ Sbjct: 226 VITEAI 231
>FPG_CORDI (Q6NGH4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 295 Score = 52.0 bits (123), Expect = 2e-06 Identities = 50/161 (31%), Positives = 71/161 (44%), Gaps = 7/161 (4%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELD--DGLEFSFTDKRRFARVR 178 H GM+G + IK NSA + V D + E F D+R F Sbjct: 84 HLGMSGQMLIK----------TQNSALHPHRRIRTTIVRSDAQECFELWFVDQRTFGYWA 133 Query: 179 LFDDPET----VPP-ISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNW 343 ET VP I+ + D L + +N + KK IK +LL+Q +SGIGN Sbjct: 134 PTTFVETAHGCVPEQITHIARDLLDPQLKRENLARLIRKKNSEIKRVLLNQEIVSGIGNI 193 Query: 344 IADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD 466 ADE+L+ ++ HP AS L+ L + Q V+ A+D Sbjct: 194 YADEMLWAARIHPQTPASHLSVAQLSNLLEHGQRVMNAALD 234
>FPG_COLP3 (Q48AD4) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 52.0 bits (123), Expect = 2e-06 Identities = 38/154 (24%), Positives = 66/154 (42%), Gaps = 1/154 (0%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVR-L 181 H GM+G I V D +K+ F + G D RRF V L Sbjct: 70 HLGMSGTI-------------RVIEQDTPVAKHDHFDLVFKHGKSLRLNDPRRFGAVLWL 116 Query: 182 FDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVL 361 +D + + +++LGP+ L + + +K+ IK L++ + G+GN A+E L Sbjct: 117 ANDEDELGLLAKLGPEPLSDDFAEGYLFSKAKNRKVPIKTFLMNNHVVVGVGNIYANEAL 176 Query: 362 YQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 +Q+ P A + +L I++V+ A+ Sbjct: 177 FQAGILPTAKAKDIDEHRMNSLTAIIKKVLSAAI 210
>FPG_BRAJA (Q89WC9) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 292 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/166 (25%), Positives = 68/166 (40%), Gaps = 16/166 (9%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWP----SKYSKFFVELDDGLEFSFTDKRRFAR 172 H GM+G+ V K A +P + + + G + F D RRF Sbjct: 72 HLGMSGSF-----RVIKPDNDAAPGEFHYPRGKDTTHDHVLFRMSSGADIVFNDPRRFGY 126 Query: 173 VRLF--DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWI 346 +++ + E P + LGP+ L S K +KA LLDQ ++G+GN Sbjct: 127 MKVIARNALEDEPLLRGLGPEPLGNEFDAAMLARSCEGKATSLKAALLDQRVVAGLGNIY 186 Query: 347 ADEVLYQSKTHPLQIASSLTRESCE----------ALHQSIQEVVK 454 E L++S P +IA++L E A+H + + +K Sbjct: 187 VCEALHRSHLSPRRIAATLATRKGEPTDHAKRLVGAIHTVLNDAIK 232
>FPG_METCA (Q602J1) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/182 (22%), Positives = 79/182 (43%), Gaps = 12/182 (6%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVR-LFDDPETVPPISELGPDALFEPMSVDNFVD 268 P K+ + + + + D RRF + + PE P ++ LGP+ L + + Sbjct: 87 PRKHDHVDLVFEGDICLRYHDPRRFGCLLWTAEPPERHPLLAALGPEPLDKAFDGAHLHR 146 Query: 269 SLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEV 448 + + +K+ ++D ++G+GN A+E L+++ HP + A ++ L + I EV Sbjct: 147 LAAGRNTAVKSFIMDSRVVAGVGNIYANEALFRAGIHPARPAGKISLARYRNLGEHIAEV 206 Query: 449 VKYAVDVDADCDR-----------FPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 + +++ R F + R G +P +V G+ I + G R T C Sbjct: 207 LAASIEQGGTTLRDFVNESGAPGYFKQVLRVYDRAG-QPCRVCGEPIRCVRLGQRATYYC 265 Query: 596 AR 601 R Sbjct: 266 PR 267
>FPG_DECAR (Q479M6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 276 Score = 50.8 bits (120), Expect = 3e-06 Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 4/128 (3%) Frame = +2 Query: 92 PSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP----ETVPPISELGPDALFEPMSVDN 259 P+K+ F + L G F D RRF V P E P ++ G + L E + + Sbjct: 91 PAKHDHFELVLA-GQILRFADPRRFGVVLWQPGPPASAECHPLLATQGIEPLSEMFTAEW 149 Query: 260 FVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSI 439 ++++++ IK L+D + GIGN A E L+++ PL+ A+ ++R E L +I Sbjct: 150 LYEAIARRSGPIKPTLMDSHLVVGIGNIYASESLFRAGISPLRAANRVSRARYEILVPAI 209 Query: 440 QEVVKYAV 463 +E + A+ Sbjct: 210 RETLSDAI 217
>FPG_NITWN (Q3SWN3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 292 Score = 50.4 bits (119), Expect = 4e-06 Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 12/122 (9%) Frame = +2 Query: 137 EFSFTDKRRF------ARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIK 298 E F D RRF AR L D+P + LGP+ L +K +K Sbjct: 115 EIVFNDPRRFGYMKIVARSALGDEPL----LKGLGPEPLGNEFDAAVLAHGCRNRKTSLK 170 Query: 299 ALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLT------RESCEALHQSIQEVVKYA 460 A LLDQ ++G+GN E L++++ P ++A++L E E L +I++V+ A Sbjct: 171 AALLDQRVVAGLGNIYVCEALFRARLSPRRLAATLAMKTGAPSERAERLVGAIRDVLNQA 230 Query: 461 VD 466 ++ Sbjct: 231 IE 232
>END8_ERWCT (Q6D7H0) Endonuclease VIII (DNA glycosylase/AP lyase Nei) (EC| 3.2.2.-) (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) Length = 262 Score = 50.1 bits (118), Expect = 6e-06 Identities = 26/97 (26%), Positives = 51/97 (52%), Gaps = 3/97 (3%) Frame = +2 Query: 203 PPISELGPDALFEPMSVDNFVDSLSKKKIG---IKALLLDQSFISGIGNWIADEVLYQSK 373 P + +GPD L ++ + + L + LLLDQ+F++G+GN++ E+L+Q++ Sbjct: 120 PFLQRIGPDVLDLSLTPEQVCERLLLPRFRRRQFSGLLLDQAFLAGLGNYLRVEILWQAQ 179 Query: 374 THPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCD 484 P AS L E + L +++ E+ + + + D Sbjct: 180 LAPQHTASQLNEEQLQTLSRALLEIPRLSYNTRGTVD 216
>FPG_RALEJ (Q476F5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 283 Score = 49.3 bits (116), Expect = 1e-05 Identities = 47/167 (28%), Positives = 68/167 (40%), Gaps = 17/167 (10%) Frame = +2 Query: 146 FTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDS------LSKKKIGIKALL 307 F D RRF V E + P L EP D+ D + IK +L Sbjct: 115 FRDPRRFGAVLWSPLSEAMLPGHPLLRGLGIEPF--DSHFDGSWLHRHTRGRSAAIKTVL 172 Query: 308 LDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD------- 466 L + + G+GN A E L+++ P A L+ CE L QS++E + A++ Sbjct: 173 LAGNIVVGVGNIYASESLFRAGIRPTTPAGRLSLARCERLAQSVRETLAQAIERGGSTLR 232 Query: 467 ----VDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 D F +E + R G +P KV G + I G R+T C Sbjct: 233 DFVGSDGASGYFQLECFVYDRAG-EPCKVCGTPVRQIVQGQRSTFYC 278
>FPG_LEIXX (Q6AFJ3) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 296 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/85 (34%), Positives = 47/85 (55%) Frame = +2 Query: 209 ISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQ 388 +S + D L F L++++ GIK +LLDQ+ ISGIGN ADE L+ ++ H Sbjct: 151 VSHIARDPLDPVFDDAAFAAVLARRRSGIKRVLLDQTLISGIGNIYADESLWAARIHYDH 210 Query: 389 IASSLTRESCEALHQSIQEVVKYAV 463 A++L+R L ++ V+ A+ Sbjct: 211 PATALSRPRVRTLLAELRRVLGRAL 235
>NEIL2_MOUSE (Q6R2P8) Endonuclease VIII-like 2 (EC 3.2.2.-) (EC 4.2.99.18)| (Nei-like 2) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (NEH2) Length = 328 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/87 (34%), Positives = 49/87 (56%) Frame = +2 Query: 206 PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPL 385 P+ E D L E +++LS+ + + LLDQ + SG+GN I +E LY+++ HPL Sbjct: 183 PVIEPTCDILSEKFHRGQALEALSQAQ-PVCYTLLDQKYFSGLGNIIKNEALYRARIHPL 241 Query: 386 QIASSLTRESCEALHQSIQEVVKYAVD 466 + S L+ S EA + VV+++ D Sbjct: 242 SLGSCLSSSSREAF---VDHVVEFSKD 265
>FPG_PROMM (Q7V8Y5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 290 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 4/113 (3%) Frame = +2 Query: 137 EFSFTDKRRFAR---VRLFDDPETV-PPISELGPDALFEPMSVDNFVDSLSKKKIGIKAL 304 E F D R F + V + PET+ + +LGP+ + L K IK+ Sbjct: 119 ELRFVDTRSFGQMWWVPPGNAPETIITGLQKLGPEPFSSAFNSSYLSKRLKGSKRPIKSA 178 Query: 305 LLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAV 463 LLDQS ++G GN DE L+ ++ P + L + E L + EV++ ++ Sbjct: 179 LLDQSIVAGAGNIYTDESLFAARIRPHTPSGQLKKVELERLCNCLTEVLRVSI 231
>Y2491_MYCBO (P64159) Putative DNA glycosylase Mb2491c (EC 3.2.2.-) (Putative| DNA-(apurinic or apyrimidinic site) lyase Mb2491c) (EC 4.2.99.18) (Putative AP lyase Mb2491c) Length = 267 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/108 (27%), Positives = 52/108 (48%) Frame = +2 Query: 131 GLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLL 310 G EF TD R DD E ++ LGPD L + + ++K + I ALL+ Sbjct: 97 GAEFG-TDLRGPTVCESIDDGEVADVVARLGPDPLRSDANPSSAWSRITKSRRPIGALLM 155 Query: 311 DQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 DQ+ I+G+GN +E+L++ + P + + +A + ++K Sbjct: 156 DQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGEPEFDAAWNDLVSLMK 203
>Y2464_MYCTU (P64158) Putative DNA glycosylase Rv2464c/MT2539 (EC 3.2.2.-)| (Putative DNA-(apurinic or apyrimidinic site) lyase Rv2464c/MT2539) (EC 4.2.99.18) (Putative AP lyase Rv2464c/MT2539) Length = 267 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/108 (27%), Positives = 52/108 (48%) Frame = +2 Query: 131 GLEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLL 310 G EF TD R DD E ++ LGPD L + + ++K + I ALL+ Sbjct: 97 GAEFG-TDLRGPTVCESIDDGEVADVVARLGPDPLRSDANPSSAWSRITKSRRPIGALLM 155 Query: 311 DQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 DQ+ I+G+GN +E+L++ + P + + +A + ++K Sbjct: 156 DQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGEPEFDAAWNDLVSLMK 203
>FPG_NITOC (Q3J7U5) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 1/123 (0%) Frame = +2 Query: 98 KYSKFFVELDDGLEFSFTDKRRFARVRLFD-DPETVPPISELGPDALFEPMSVDNFVDSL 274 K+ + L++G F D RRF V +P P + LGP+ L Sbjct: 89 KHDHLDIVLNNGRCLRFNDPRRFGSVSWTQANPLHHPLLEILGPEPLESLFDGHYLFKHS 148 Query: 275 SKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK 454 ++ +KA +++ ++G+GN A+E L+ + HP + AS + + L ++ + V+ Sbjct: 149 RHRRTSVKAFIMNHRIVAGVGNIYANEALFLAGIHPRRSASRIGLARYQRLAETTKTVLY 208 Query: 455 YAV 463 A+ Sbjct: 209 NAI 211
>FPG_BRUSU (Q8FXR6) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 292 Score = 45.4 bits (106), Expect = 1e-04 Identities = 56/222 (25%), Positives = 92/222 (41%), Gaps = 24/222 (10%) Frame = +2 Query: 5 HEGMAGAIYIK-----GVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLE--FSFTDKRR 163 H GM+G+ I+ G+ + + NS D + F + DG + D RR Sbjct: 72 HLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHD----HVVFHLMRPDGASARIIYNDPRR 127 Query: 164 FARVRLFDDP---ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGI 334 F + LF + E P + +LG + +S + ++ +KA LLDQ I+G+ Sbjct: 128 FGFM-LFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRKPLKAALLDQRLIAGL 186 Query: 335 GNWIADEVLYQSKTHPLQIASSLTRES--CEALHQSIQEVVKYA-----------VDVDA 475 GN E L+++ P++ A S+ E E L +I+ V+ A + D Sbjct: 187 GNIYVCEALWRAGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADG 246 Query: 476 DCDRFPVEWLFHHRWGKK-PGKVDGKKIEFITAGGRTTALCA 598 F + + R GK G +E + GR+T CA Sbjct: 247 ALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCA 288
>FPG_BRUME (Q8YED2) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 292 Score = 45.4 bits (106), Expect = 1e-04 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 24/222 (10%) Frame = +2 Query: 5 HEGMAGAIYIK-----GVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLE--FSFTDKRR 163 H GM+G+ I+ G+ + + NS D + F + DG + D RR Sbjct: 72 HLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHD----HVVFHLMRPDGASARIIYNDPRR 127 Query: 164 FARVRLFDDP---ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGI 334 F + LF + E P + +LG + +S + ++ +KA LLDQ I+G+ Sbjct: 128 FGFM-LFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGL 186 Query: 335 GNWIADEVLYQSKTHPLQIASSLTRES--CEALHQSIQEVVKYA-----------VDVDA 475 GN E L++ P++ A S+ E E L +I+ V+ A + D Sbjct: 187 GNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADG 246 Query: 476 DCDRFPVEWLFHHRWGKK-PGKVDGKKIEFITAGGRTTALCA 598 F + + R GK G +E + GR+T CA Sbjct: 247 ALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCA 288
>FPG_BRUAB (Q57A83) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 292 Score = 45.4 bits (106), Expect = 1e-04 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 24/222 (10%) Frame = +2 Query: 5 HEGMAGAIYIK-----GVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLE--FSFTDKRR 163 H GM+G+ I+ G+ + + NS D + F + DG + D RR Sbjct: 72 HLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHD----HVVFHLMRPDGASARIIYNDPRR 127 Query: 164 FARVRLFDDP---ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGI 334 F + LF + E P + +LG + +S + ++ +KA LLDQ I+G+ Sbjct: 128 FGFM-LFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGL 186 Query: 335 GNWIADEVLYQSKTHPLQIASSLTRES--CEALHQSIQEVVKYA-----------VDVDA 475 GN E L++ P++ A S+ E E L +I+ V+ A + D Sbjct: 187 GNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADG 246 Query: 476 DCDRFPVEWLFHHRWGKK-PGKVDGKKIEFITAGGRTTALCA 598 F + + R GK G +E + GR+T CA Sbjct: 247 ALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCA 288
>FPG_BRUA2 (Q2YQP8) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 292 Score = 45.4 bits (106), Expect = 1e-04 Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 24/222 (10%) Frame = +2 Query: 5 HEGMAGAIYIK-----GVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLE--FSFTDKRR 163 H GM+G+ I+ G+ + + NS D + F + DG + D RR Sbjct: 72 HLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHD----HVVFHLMRPDGASARIIYNDPRR 127 Query: 164 FARVRLFDDP---ETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGI 334 F + LF + E P + +LG + +S + ++ +KA LLDQ I+G+ Sbjct: 128 FGFM-LFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGL 186 Query: 335 GNWIADEVLYQSKTHPLQIASSLTRES--CEALHQSIQEVVKYA-----------VDVDA 475 GN E L++ P++ A S+ E E L +I+ V+ A + D Sbjct: 187 GNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADG 246 Query: 476 DCDRFPVEWLFHHRWGKK-PGKVDGKKIEFITAGGRTTALCA 598 F + + R GK G +E + GR+T CA Sbjct: 247 ALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCA 288
>FPG_AZOSE (Q5P728) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 270 Score = 43.1 bits (100), Expect = 7e-04 Identities = 39/162 (24%), Positives = 69/162 (42%), Gaps = 12/162 (7%) Frame = +2 Query: 152 DKRRFARVRLF-DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFIS 328 D RRF V D + P ++ LG + L + ++ ++ IK L+D + Sbjct: 106 DPRRFGLVLWHAGDGLSHPLLAALGREPLERGFTGAWLHEATRGVRLSIKQTLMDAHRVV 165 Query: 329 GIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDV-----------DA 475 G+GN A E L++++ HPL A ++ + L S++E + A+D D Sbjct: 166 GVGNIYASESLFRARIHPLAPAGAIGPQRLARLVASVRETLLAAIDAGGSTLRDFVGGDG 225 Query: 476 DCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALCAR 601 F ++ + R G +V + + G R+T C R Sbjct: 226 RAGYFQQQYFVYGREG-LACRVCATPVRRVVIGQRSTFFCPR 266
>FPG_BURMA (Q62FC7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 271 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 15/171 (8%) Frame = +2 Query: 128 DGLEFSFTDKRRFARV----RLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGI 295 D F D RRF V R D P ++ LG EP S + + + Sbjct: 101 DEFVLRFRDPRRFGAVLWHPRDAGDVHAHPLLASLG----VEPFSAALLFGRTRGRTVSV 156 Query: 296 KALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVD--- 466 K LL + G+GN A E L+++ P A ++ E L +++ + A++ Sbjct: 157 KQALLAGDIVVGVGNIYASESLFRAGIRPTTAAGRVSLPRYERLADAVRATLADAIERGG 216 Query: 467 --------VDADCDRFPVEWLFHHRWGKKPGKVDGKKIEFITAGGRTTALC 595 + + F ++ + R G +P +V G I I G R+T C Sbjct: 217 STLRDFVGSNGESGYFQLDCFVYDRAG-EPCRVCGAPIRQIVQGQRSTYFC 266
>NEIL2_BOVIN (Q6IE77) Endonuclease VIII-like 2 (EC 3.2.2.-) (EC 4.2.99.18)| (Nei-like 2) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (NEH2) Length = 328 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/87 (32%), Positives = 44/87 (50%) Frame = +2 Query: 206 PISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPL 385 P+ D L E +++L +++ I LLDQ + SG+GN I +E L+++ HPL Sbjct: 183 PVVSPASDILSEKFHRGQALEALGREQ-PICYTLLDQRYFSGLGNIIKNEALFRAGIHPL 241 Query: 386 QIASSLTRESCEALHQSIQEVVKYAVD 466 S L EAL + VV ++ D Sbjct: 242 SPGSLLGLPRLEAL---VDHVVAFSAD 265
>NEIL2_HUMAN (Q969S2) Endonuclease VIII-like 2 (EC 3.2.2.-) (EC 4.2.99.18)| (Nei-like 2) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (NEH2) Length = 331 Score = 41.2 bits (95), Expect = 0.003 Identities = 20/47 (42%), Positives = 28/47 (59%) Frame = +2 Query: 305 LLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 LLDQ + SG+GN I +E LY++ HPL + S L+ E L + E Sbjct: 219 LLDQRYFSGLGNIIKNEALYRAGIHPLSLGSVLSASRREVLVDHVVE 265
>END8_SHIFL (Q83LZ7) Endonuclease VIII (DNA glycosylase/AP lyase Nei) (EC| 3.2.2.-) (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) Length = 262 Score = 40.0 bits (92), Expect = 0.006 Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Frame = +2 Query: 197 TVPPISELGPDALFEPMSVDNFVDSLSKKKIGIK---ALLLDQSFISGIGNWIADEVLYQ 367 T P + +GPD L ++ + + L + + LLLDQ+F++G+GN++ E+L+Q Sbjct: 118 THPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQ 177 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYA 460 A L +AL ++ E+ +++ Sbjct: 178 VGLTGNHKAKDLNAAQLDALAHALLEIPRFS 208
>END8_SALTY (Q8ZQU6) Endonuclease VIII (DNA glycosylase/AP lyase Nei) (EC| 3.2.2.-) (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) Length = 262 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Frame = +2 Query: 197 TVPPISELGPDAL---FEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQ 367 T P + +GPD L P V + S + LLLDQSF++G+GN++ E+L+Q Sbjct: 118 THPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQSFLAGLGNYLRVEILWQ 177 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCD 484 A L AL ++ ++ + + D Sbjct: 178 VGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQAD 216
>END8_SALTI (Q8Z8D2) Endonuclease VIII (DNA glycosylase/AP lyase Nei) (EC| 3.2.2.-) (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) Length = 262 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Frame = +2 Query: 197 TVPPISELGPDAL---FEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQ 367 T P + +GPD L P V + S + LLLDQSF++G+GN++ E+L+Q Sbjct: 118 THPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQSFLAGLGNYLRVEILWQ 177 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCD 484 A L AL ++ ++ + + D Sbjct: 178 VGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQAD 216
>END8_ECOLI (P50465) Endonuclease VIII (DNA glycosylase/AP lyase Nei) (EC| 3.2.2.-) (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) Length = 262 Score = 40.0 bits (92), Expect = 0.006 Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Frame = +2 Query: 197 TVPPISELGPDALFEPMSVDNFVDSLSKKKIGIK---ALLLDQSFISGIGNWIADEVLYQ 367 T P + +GPD L ++ + + L + + LLLDQ+F++G+GN++ E+L+Q Sbjct: 118 THPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQ 177 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYA 460 A L +AL ++ E+ +++ Sbjct: 178 VGLTGNHKAKDLNAAQLDALAHALLEIPRFS 208
>END8_ECO57 (Q8X9C6) Endonuclease VIII (DNA glycosylase/AP lyase Nei) (EC| 3.2.2.-) (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) Length = 262 Score = 38.9 bits (89), Expect = 0.013 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Frame = +2 Query: 197 TVPPISELGPDALFEPMSVDNFVDSLSKKKIGIK---ALLLDQSFISGIGNWIADEVLYQ 367 T P + +GPD L ++ + + L + + LLLDQ+F++G+GN++ E+L+Q Sbjct: 118 THPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQ 177 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEVVKYA 460 A L +AL ++ ++ +++ Sbjct: 178 VGLTGNHKAKDLNAAQLDALAHALLDIPRFS 208
>NEIL1_HUMAN (Q96FI4) Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18)| (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1) (FPG1) Length = 389 Score = 38.1 bits (87), Expect = 0.023 Identities = 36/103 (34%), Positives = 48/103 (46%), Gaps = 3/103 (2%) Frame = +2 Query: 134 LEFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSV-DNFVDSLSKKKIG--IKAL 304 L F D RRF R L + GP L E +N + +L+ K I Sbjct: 109 LALCFVDIRRFGRWDLGGKWQP-----GRGPCVLQEYQQFRENVLRNLADKAFDRPICEA 163 Query: 305 LLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQ 433 LLDQ F +GIGN++ E+LY+ K P + A S+ EAL Q Sbjct: 164 LLDQRFFNGIGNYLRAEILYRLKIPPFEKARSV----LEALQQ 202
>END8_ECOL6 (Q8FJU5) Endonuclease VIII (DNA glycosylase/AP lyase Nei) (EC| 3.2.2.-) (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase Nei) Length = 262 Score = 38.1 bits (87), Expect = 0.023 Identities = 26/103 (25%), Positives = 51/103 (49%), Gaps = 5/103 (4%) Frame = +2 Query: 197 TVPPISELGPDALFEPMSVDNFVDSLSKKKIGIK---ALLLDQSFISGIGNWIADEVLYQ 367 T P + +GPD L ++ + + L + + LLLDQ+F++G+GN++ E+L+Q Sbjct: 118 THPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQ 177 Query: 368 SKTHPLQIASSLTRESCEALHQSIQEV--VKYAVDVDADCDRF 490 A L +AL ++ ++ + YA D +++ Sbjct: 178 VGLTGNHKAKDLNAAQLDALAHALLDIPRLSYATRGQVDENKY 220
>NEIL1_MOUSE (Q8K4Q6) Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18)| (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1) Length = 388 Score = 37.4 bits (85), Expect = 0.039 Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Frame = +2 Query: 254 DNFVDSLSKKKIG--IKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEAL 427 +N + +LS K I LLDQ F +GIGN++ E+LY+ K P + A R EAL Sbjct: 145 ENVLRNLSDKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKA----RTVLEAL 200 Query: 428 HQ 433 Q Sbjct: 201 QQ 202
>FPG_PSYAR (Q4FUU7) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 308 Score = 37.0 bits (84), Expect = 0.050 Identities = 28/126 (22%), Positives = 55/126 (43%), Gaps = 17/126 (13%) Frame = +2 Query: 137 EFSFTDKRRFARVRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKK----------- 283 + + D RRF + L+ + ++ LGP+ L + + D + + Sbjct: 121 QLHYYDPRRFGSI-LWLEEYGDKLLNHLGPEPLSDAFTADYLYHLIQRSRQSIQTQNSKS 179 Query: 284 ------KIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQE 445 K IK+++++Q + G+GN A E LY S HP A+ ++ L I+ Sbjct: 180 IKKQPIKRAIKSVIMEQQAVVGVGNIYATESLYLSGIHPATPANEVSYAQIVILVAHIKT 239 Query: 446 VVKYAV 463 +++ A+ Sbjct: 240 ILQKAI 245
>NEIL3_HUMAN (Q8TAT5) Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase| FPG2) Length = 605 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 2/149 (1%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLF 184 H GM G I I + KYK A + +K F + L S ++R ++ Sbjct: 95 HFGMKGFIMINPLEY-KYKNGASPVLEVQLTKDLICFFDSSVELRNSMESQQRIRMMKEL 153 Query: 185 D--DPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIADEV 358 D PE F + ++ V + +G +L+DQ+ + G+GN I +E Sbjct: 154 DVCSPE-------------FSFLRAESEVKKQKGRMLG--DVLMDQNVLPGVGNIIKNEA 198 Query: 359 LYQSKTHPLQIASSLTRESCEALHQSIQE 445 L+ S HP LT E L + I++ Sbjct: 199 LFDSGLHPAVKVCQLTDEQIHHLMKMIRD 227
>FPG_RHIME (Q59752) Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)| (FAPY-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (EC 4.2.99.18) (AP lyase mutM) Length = 300 Score = 34.3 bits (77), Expect = 0.33 Identities = 41/168 (24%), Positives = 66/168 (39%), Gaps = 15/168 (8%) Frame = +2 Query: 5 HEGMAGAIYIKGVAVTKYKRSAVNSADDWP----SKYSKFFVELDDG---LEFSFTDKRR 163 H GM+G+ I+ + A A P K+ LD G + D RR Sbjct: 72 HLGMSGSFRIEKGPIEAGADPATPGAFHHPRGKDEKHDHVVFHLDGGSGPARVIYNDPRR 131 Query: 164 FARVRLFDDPETVPPI--SELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIG 337 F + L + LG + + + K +KA LLDQ I+G+G Sbjct: 132 FGFMDLARRSALADHVFLRGLGEEPTGNALDAAYLATRFAGKIQPLKAALLDQRTIAGLG 191 Query: 338 NWIADEVLYQSKTHPLQIASSLT------RESCEALHQSIQEVVKYAV 463 N E L++S P + A +L +++ AL + I+ V+ A+ Sbjct: 192 NIYVCEALWRSGLSPKRSAGTLVDKRGRPKQALIALTERIRAVIADAI 239
>TRPF_METKA (Q8TXZ9) N-(5'-phosphoribosyl)anthranilate isomerase (EC 5.3.1.24)| (PRAI) Length = 216 Score = 33.1 bits (74), Expect = 0.73 Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 15/118 (12%) Frame = +2 Query: 185 DDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIG----------IKALLLDQSFISGI 334 +DPET +SELG D + L ++ IG + A+LLD G Sbjct: 84 EDPETCEELSELGLDVIKTFWVDQRGSVWLGEELIGDEVLAEYCEIVDAVLLDTKSAEGG 143 Query: 335 G-----NWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCDRFP 493 G +W A L + P+ +A L E+ + +++++V YAVD + ++ P Sbjct: 144 GSGERHDWDASARLVRRLDVPVILAGGLNPEN---VREAVEKVRPYAVDTSSGVEKEP 198
>RS13_CHLPN (Q9Z7S6) 30S ribosomal protein S13| Length = 122 Score = 32.7 bits (73), Expect = 0.95 Identities = 23/70 (32%), Positives = 37/70 (52%) Frame = +2 Query: 263 VDSLSKKKIGIKALLLDQSFISGIGNWIADEVLYQSKTHPLQIASSLTRESCEALHQSIQ 442 +D +KKK+ I ++I GIG+ +DE++ + K P AS LT E L+ +Q Sbjct: 7 IDIPAKKKLKISL-----TYIYGIGSARSDEIIKKLKLDPEARASELTEEEVGRLNSLLQ 61 Query: 443 EVVKYAVDVD 472 +Y V+ D Sbjct: 62 S--EYTVEGD 69
>NEIL3_MOUSE (Q8K203) Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase| FPG2) Length = 606 Score = 32.0 bits (71), Expect = 1.6 Identities = 14/40 (35%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Frame = +2 Query: 302 LLLDQSFISGIGNWIADEVLYQSKTHP-LQIASSLTRESC 418 +LLDQ + G+GN I +E L+ S HP +++ +++C Sbjct: 181 VLLDQRVLPGVGNIIKNEALFDSGLHPAVKVCQLSDKQAC 220
>SYD_MYCGE (P47282) Aspartyl-tRNA synthetase (EC 6.1.1.12) (Aspartate--tRNA| ligase) (AspRS) Length = 550 Score = 30.8 bits (68), Expect = 3.6 Identities = 22/71 (30%), Positives = 34/71 (47%) Frame = +2 Query: 173 VRLFDDPETVPPISELGPDALFEPMSVDNFVDSLSKKKIGIKALLLDQSFISGIGNWIAD 352 ++LF +T P I E DAL E ++D ++++ K LLL FI I NW Sbjct: 88 IKLFSKSKTPPLIIEDETDALEEVRLKYRYLDL--RRRLMQKRLLLRHQFILAIRNWFNQ 145 Query: 353 EVLYQSKTHPL 385 + + +T L Sbjct: 146 QGFIEIETPTL 156
>CARB_THET2 (P96495) Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)| (Carbamoyl-phosphate synthetase ammonia chain) Length = 1028 Score = 30.4 bits (67), Expect = 4.7 Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 16/108 (14%) Frame = +2 Query: 44 AVTKYKRSAVNSADD-WPSKYSKFFV------ELDDGLEFSFTD--------KRRFARVR 178 A T Y S D+ WPS+ K + + G+EF + + F + Sbjct: 534 AYTPYHYSTYELEDEVWPSQKPKVVILGSGPIRIGQGVEFDYATVHAVWALKEAGFETIM 593 Query: 179 LFDDPETVPPISELGPDALFEPMSVDNFVDSLS-KKKIGIKALLLDQS 319 + +PETV + FEP+++++ ++ + +K IG+ A L Q+ Sbjct: 594 VNSNPETVSTDYDTADRLYFEPLTLEDVLNIVEHEKPIGVIATLGGQT 641
>LAG3_CAEEL (Q09260) Protein lag-3 (Abnormal germ line proliferation protein 3)| (Abnormal cell lineage protein 3) Length = 490 Score = 30.4 bits (67), Expect = 4.7 Identities = 15/47 (31%), Positives = 23/47 (48%) Frame = -2 Query: 263 QNCQRTSAQREHPDLAQKLEVQFQDHQITELLQSASYQ*RKTPSHHQ 123 Q QR QR + Q+ + Q Q+HQ ++L Q ++ HHQ Sbjct: 357 QEMQRIEQQRRQQIMQQQQQQQQQEHQRQQMLLQQQQQQQQMQQHHQ 403
>POLN_FCVUR (Q66914) Non-structural polyprotein [Contains: p5.6; p32; Helicase| (2C-like protein) (p39); 3A-like protein (p30); Viral genome-linked protein (VPg) (p13); Thiol protease P3C (EC 3.4.22.-) (3C-like protease) (3C-pro); RNA-directed RNA polymera Length = 1763 Score = 30.0 bits (66), Expect = 6.2 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Frame = +2 Query: 344 IADEVLYQSKTHPLQIASSLTRESCEALHQSIQEVVK-YAVD 466 ++D + + P+Q+ ++ S EALHQ I+ K YAVD Sbjct: 1443 VSDAITANHQYGPVQVGINMDSPSVEALHQRIKSAAKVYAVD 1484
>SYFB_WOLSU (Q7M8Y8) Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20)| (Phenylalanine--tRNA ligase beta chain) (PheRS) Length = 786 Score = 30.0 bits (66), Expect = 6.2 Identities = 15/64 (23%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Frame = +2 Query: 23 AIYIKGVAVTKYKRSA---VNSADDWPSKYSKFFVELDDGLEFSFTDKRRFARVRLFDDP 193 A + GV++ Y+ A +++D+ P K S + ++GLE + +++ + + + + Sbjct: 258 ATLVSGVSIKAYRHDACLPASTSDEKPLKASIMIKKDENGLESVYAGEKKLSTIGVSQNR 317 Query: 194 ETVP 205 ET+P Sbjct: 318 ETMP 321
>CEP2_HUMAN (Q9BV73) Centrosomal protein 2 (Centrosomal Nek2-associated protein| 1) (C-NAP1) (Centrosome protein 250) (Centrosome-associated protein CEP250) Length = 2442 Score = 30.0 bits (66), Expect = 6.2 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Frame = -2 Query: 350 LQSNYQCLI*SSDLAKELLFQSSSCSVSPQNCQRTSAQREHPDLAQKLEVQFQD---HQI 180 LQ Q L+ ++L++ L +++ S CQ S Q E Q+ E+Q QD + Sbjct: 1977 LQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQED 2036 Query: 179 TELLQSASYQ*RKTPSHHQARRKTWSTWTASR 84 + LQ A Q + H Q R + A R Sbjct: 2037 VQQLQQALAQRDEELRHQQEREQLLEKSLAQR 2068
>ENO_TUBBO (Q6W3C0) Enolase (EC 4.2.1.11) (2-phosphoglycerate dehydratase)| (2-phospho-D-glycerate hydro-lyase) Length = 440 Score = 29.6 bits (65), Expect = 8.0 Identities = 18/79 (22%), Positives = 34/79 (43%), Gaps = 2/79 (2%) Frame = +2 Query: 374 THPLQIASSLTRESCEALHQSIQEVVKYAVDVDADCDRFPVEW--LFHHRWGKKPGKVDG 547 T+P++I ++ +SC AL + ++ + A D + W + HR G+ Sbjct: 326 TNPIRIKRAIDEKSCNALLLKVNQIATLTESIQAAKDSYSAGWGVMVSHRSGETEDVTIA 385 Query: 548 KKIEFITAGGRTTALCART 604 + + AG T AR+ Sbjct: 386 DIVVGLRAGQIKTGAPARS 404 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,117,239 Number of Sequences: 219361 Number of extensions: 1807842 Number of successful extensions: 5780 Number of sequences better than 10.0: 185 Number of HSP's better than 10.0 without gapping: 5533 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5733 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6086476506 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
