>MED20_YEAST (P34162) RNA polymerase II mediator complex subunit 20 (Suppressor|
           of RNA polymerase B 2) (Hyper-recombination suppressor
           protein 2)
          Length = 210

 Score = 31.2 bits (69), Expect = 0.67
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 10/94 (10%)
 Frame = +2

Query: 62  SINKASYRLDLKNIPIAASRLQHTIIQCHKHASAQQQHLVPQVDTSKTNQLLLRLP---- 229
           SI+  +YR  +KN+P   S+L ++I     H   +Q  L+       T      +P    
Sbjct: 36  SIDFRTYRCSIKNLPADVSKLMYSIT---FHHHGRQTVLIKDNSAMVTTAAAADIPPALV 92

Query: 230 --GFCWGLPKT-KTVLVSKAQN---QLSMLAGDA 313
             G   G+P++  T+L SK  N   Q  ++ GDA
Sbjct: 93  FNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDA 126

>MLL3_HUMAN (Q8NEZ4) Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog|
            (Histone-lysine N-methyltransferase, H3 lysine-4 specific
            MLL3) (EC 2.1.1.43) (Homologous to ALR protein)
          Length = 4911

 Score = 30.4 bits (67), Expect = 1.1
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +1

Query: 163  PTTAPSSPSRHFKNKPTFIAPSWLLLGASKDQDGT 267
            P T P+SPS H  + P FIAP   +L  + + + T
Sbjct: 2940 PPTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVT 2974

>IRS1_RAT (P35570) Insulin receptor substrate 1 (IRS-1) (pp185)|
          Length = 1235

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
 Frame = +2

Query: 146  HKHASAQQQHLVPQVDT-SKTNQLLLRLPGFCWGLPKTKTVLVSKAQNQLSMLAGDAELL 322
            H H  A Q HL  +VDT ++TN  L R      G PK  T+   + Q Q       + L 
Sbjct: 826  HPHHHALQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQQQQQQQQQSSLH 885

Query: 323  EPQ 331
             P+
Sbjct: 886  PPE 888

>FMT_MYCLE (Q9CCQ0) Methionyl-tRNA formyltransferase (EC 2.1.2.9)|
          Length = 318

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 12/27 (44%), Positives = 14/27 (51%)
 Frame = -2

Query: 249 GSPQQKPGRRNKSWFVFEVSTWGTRCC 169
           G P  +P R N   FV E+S W   CC
Sbjct: 59  GIPLLRPARPNSPVFVSELSEWAPECC 85

>LRP1_CHICK (P98157) Low-density lipoprotein receptor-related protein 1 precursor|
            (LRP) (Alpha-2-macroglobulin receptor) (A2MR)
          Length = 4543

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
 Frame = -3

Query: 209  GLFLKCRLG-ELGAVVGLKHACDIE*LCAVIWMPQSECSSNPTYNWPC*CYSGFLL 45
            G+   C LG ELGA       C I+  CA       +C  +  YN  C CY G++L
Sbjct: 1201 GIVCSCPLGMELGAD---NKTCQIQSYCAKHLKCSQKCEQDK-YNVKCSCYEGWML 1252

>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)|
          Length = 1257

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
 Frame = +1

Query: 154  CFSPTTA--PSSPSRHFKNKPTFIAPSWLLLGASKDQDGTCEQSSKST 291
            C SPT +  P SP++H   + T      L   A+  Q    +QSSK+T
Sbjct: 1124 CVSPTRSSRPGSPTKHLAQRHTAATAQRLTNAAATHQQQHQQQSSKTT 1171

>FTSH_CYACA (O19922) Cell division protein ftsH homolog (EC 3.4.24.-)|
          Length = 614

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
 Frame = +2

Query: 50  EILSSINKASYRLDLKNIPIAASRLQHTIIQCHKHASAQQQHLVPQVDTSKTNQLLLR-- 223
           EI  SI+K      L+  P+A SR++  +I  H+   A     +P  D  +   L+ R  
Sbjct: 403 EIEDSIDKII--AGLEGSPLADSRIKR-LIAYHEAGHAVAATFLPHHDPVQKVTLIPRRQ 459

Query: 224 LPGFCWGLPKTKTVLVSKAQ---NQLSMLAGDA 313
             G  W LP     LVSK+Q     ++ LAG A
Sbjct: 460 AKGLTWFLPNDDQFLVSKSQILSKIIAALAGRA 492

>IRS1_CERAE (Q28224) Insulin receptor substrate 1 (IRS-1)|
          Length = 1251

 Score = 28.9 bits (63), Expect = 3.3
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
 Frame = +2

Query: 146 HKHASAQQQHLVPQVDT-SKTNQLLLRLPGFCWGLPKTKTVLVSKAQNQ 289
           H H    Q HL  +VDT ++TN  L R      G PK  T+  ++ Q Q
Sbjct: 829 HPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQ 877

>KR105_HUMAN (P60370) Keratin-associated protein 10-5 (Keratin-associated|
           protein 10.5) (High sulfur keratin-associated protein
           10.5) (Keratin-associated protein 18-5)
           (Keratin-associated protein 18.5)
          Length = 271

 Score = 28.9 bits (63), Expect = 3.3
 Identities = 16/48 (33%), Positives = 20/48 (41%)
 Frame = +1

Query: 139 SMSQACFSPTTAPSSPSRHFKNKPTFIAPSWLLLGASKDQDGTCEQSS 282
           S + +C  P    SSP +     P    P   L   SKD    C+QSS
Sbjct: 68  SCTPSCCQPACCASSPCQQACCVPVCCKPVCCLPTCSKDSSSCCQQSS 115

>IRS1_HUMAN (P35568) Insulin receptor substrate 1 (IRS-1)|
          Length = 1242

 Score = 28.9 bits (63), Expect = 3.3
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
 Frame = +2

Query: 146 HKHASAQQQHLVPQVDT-SKTNQLLLRLPGFCWGLPKTKTVLVSKAQNQ 289
           H H    Q HL  +VDT ++TN  L R      G PK  T+  ++ Q Q
Sbjct: 831 HPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQ 879

>YLAA_BACSU (O07625) Hypothetical protein ylaA|
          Length = 646

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 6/47 (12%)
 Frame = +2

Query: 95  KNIPIAASRLQHTIIQ------CHKHASAQQQHLVPQVDTSKTNQLL 217
           KNI +A SRLQH I+         K   + Q  +V   D+SKT + +
Sbjct: 509 KNISMANSRLQHQILSIFDARGSEKKKKSSQGDMVMYTDSSKTYEFV 555

>Y1146_HAEIN (P45071) UPF0042 protein HI1146|
          Length = 285

 Score = 27.7 bits (60), Expect = 7.4
 Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
 Frame = +2

Query: 38  PNKXEILS-SINKASYRLDLKNIPIAASRLQHTIIQCHKH 154
           P   +ILS S +  +  LD++NIP +A  L+ T+    KH
Sbjct: 38  PQLTDILSQSQSSVAISLDIRNIPNSAHSLKQTLSTLQKH 77

>IRS1_MOUSE (P35569) Insulin receptor substrate 1 (IRS-1)|
          Length = 1233

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
 Frame = +2

Query: 146 HKHASAQQQHLVPQVDT-SKTNQLLLRLPGFCWGLPKTKTVLVSKAQNQ 289
           H H    Q HL  +VDT ++TN  L R      G PK  T+   + Q Q
Sbjct: 826 HPHHHVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQQ 874

>MUTS_BACHD (Q9KAC0) DNA mismatch repair protein mutS|
          Length = 865

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 10/80 (12%)
 Frame = +2

Query: 89  DLKNIPIAASRLQHTIIQCHKHASAQQQHL----------VPQVDTSKTNQLLLRLPGFC 238
           D+KN+ ++A   Q T++  HK    Q              +P V T +   LL  L G  
Sbjct: 732 DVKNVHVSAVEEQGTVVFLHKVVDGQADRSYGIYVAELAGLPNVVTERAETLLAELEGEK 791

Query: 239 WGLPKTKTVLVSKAQNQLSM 298
             +   K V  +    QLS+
Sbjct: 792 EIVASEKEVASTNEPTQLSL 811

>ZEP1_MOUSE (Q03172) Zinc finger protein 40 (Transcription factor|
           alphaA-CRYBP1) (Alpha A-crystallin-binding protein I)
           (Alpha A-CRYBP1)
          Length = 2688

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 17/58 (29%), Positives = 27/58 (46%)
 Frame = +2

Query: 110 AASRLQHTIIQCHKHASAQQQHLVPQVDTSKTNQLLLRLPGFCWGLPKTKTVLVSKAQ 283
           +  + +    QC  H  + Q HLVP++  S+ NQ L    GF   L    T+  +K +
Sbjct: 269 STQKSEQVAAQCVSHLYSSQDHLVPKL--SQQNQQLPGHLGFTGSLTNLHTLESTKLE 324


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,640,300
Number of Sequences: 219361
Number of extensions: 865298
Number of successful extensions: 2703
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 2467
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2699
length of database: 80,573,946
effective HSP length: 87
effective length of database: 61,489,539
effective search space used: 1475748936
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)