ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | bags15m21 |
|---|---|
| Clone Library Name | barley_pub |
>LEU21_METMA (Q8PZT3) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 391 Score = 151 bits (382), Expect = 1e-36 Identities = 73/162 (45%), Positives = 103/162 (63%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ AKDL L +IG+ ++GATY+++EF G I L++ RMTLCNM IE G K G+VP D Sbjct: 147 HVYAKDLTLYLIGKTGIAGATYKAVEFYGQAISELSVAGRMTLCNMAIEMGAKTGIVPPD 206 Query: 195 ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVK 374 E TF +L+ + YEPVYSD A + ++ +D +EP VA PH DN E + Sbjct: 207 EKTFDFLKNRAVAPYEPVYSDPDASYLKEFVYDAGDIEPQVACPHQVDNVKPVGEVEGTH 266 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQ 500 +D+V+IG+CT G+ ED AA V GKKV V T ++PA++ Sbjct: 267 VDQVFIGTCTNGRLEDLEVAASVL--KGKKVTVRTIIIPASR 306
>LEU21_METAC (Q8TLF1) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 424 Score = 150 bits (380), Expect = 2e-36 Identities = 72/159 (45%), Positives = 103/159 (64%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKDL L +IG+ ++GATY+++EF G I LT+ RMTLCNM IE G K G+VP DE T Sbjct: 183 AKDLTLYLIGKTGIAGATYKAVEFYGQAIRELTVAGRMTLCNMAIEMGAKTGIVPPDEKT 242 Query: 204 FKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVKIDR 383 F++L+ + + YEPVY+D A + ++ +D +EP VA PH DN E + +D+ Sbjct: 243 FEFLKNRAAATYEPVYADPDAVYLEEFTYDADDIEPQVACPHQVDNVKPVGEVEGTHVDQ 302 Query: 384 VYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQ 500 V+IG+CT G+ ED AA V GK+V V T ++PA++ Sbjct: 303 VFIGTCTNGRLEDLEVAAAVL--KGKQVAVRTIVIPASR 339
>LEU2_AQUAE (O67078) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 432 Score = 149 bits (377), Expect = 4e-36 Identities = 76/174 (43%), Positives = 113/174 (64%), Gaps = 5/174 (2%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P+++ KDLIL IG+I V GA YR+MEF G TI +L+ME+R T+ NM IEAGGK+G+ Sbjct: 167 KLKPWVMGKDLILYTIGQIGVDGALYRAMEFDGETIRNLSMEQRFTIANMAIEAGGKSGI 226 Query: 183 VPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAREC 362 + DE T +Y++ + ++ SD A ++S Y +D S++EP+VA P+ P N E Sbjct: 227 ISPDEKTIEYVKQRAKRPWKVYQSDPDAEYHSVYEWDASQIEPLVAWPYLPSNVHPVSES 286 Query: 363 KDVKIDRVYIGSCTGGKTEDFIAAAKVF---LASGKKVK--VPTFLVPATQKVW 509 + ID+ +IGSCT G+ ED AAKVF L GKKV V ++PA++ ++ Sbjct: 287 THITIDQAFIGSCTNGRIEDLRVAAKVFEAALKQGKKVHPYVRCIVIPASKAIY 340
>LEU21_METKA (Q8TVF2) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 145 bits (367), Expect = 6e-35 Identities = 71/169 (42%), Positives = 105/169 (62%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + AKD++L++ GEI GATY ++E+ G + +++ +RM LCNM IE G K G+ Sbjct: 166 ELPEGVYAKDVVLKVTGEIGADGATYMAIEYHGEVVREMSVSDRMCLCNMAIEMGAKTGM 225 Query: 183 VPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAREC 362 VP DE T +Y++ + E PV D AR+ ++ DVS LEP VAKP SPDN E Sbjct: 226 VPPDEKTLEYVKKRAGTEGRPVEPDPDARYEAELTLDVSDLEPQVAKPFSPDNVVPVGEV 285 Query: 363 KDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 + + ID+V+IGSCT G+ ED AA+V V ++PA+++V+ Sbjct: 286 EGIAIDQVFIGSCTNGRYEDLKVAAEVLEGEEVHDDVRLIVIPASREVY 334
>LEU21_PYRFU (Q8U2A1) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 424 Score = 144 bits (362), Expect = 2e-34 Identities = 76/173 (43%), Positives = 114/173 (65%), Gaps = 4/173 (2%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P++ +KDLIL IG+I V+GA Y+ MEF G IE L++E+RMT+ NM IEAG K G+ Sbjct: 169 DLQPWVTSKDLILYTIGDIGVNGALYKVMEFSGEVIEKLSVEQRMTMTNMAIEAGAKTGI 228 Query: 183 VPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRA-LARE 359 + D+ T +Y++G+ EY+ SD A++Y +DVSK+EP VA PH P+N +++ Sbjct: 229 IEPDKKTIEYVKGRAKREYKIYKSDEDAKYYKVIEYDVSKIEPQVAFPHLPENTVPISKA 288 Query: 360 CK-DVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVK--VPTFLVPATQKVW 509 K ++KID+V IGSCT G+ ED AA+V G+KV V ++P + V+ Sbjct: 289 AKMNIKIDQVVIGSCTNGRLEDLRMAAEVL--EGQKVAPWVRLIILPCSPTVY 339
>LEU2_WOLSU (Q7M9Z9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 142 bits (358), Expect = 7e-34 Identities = 73/177 (41%), Positives = 111/177 (62%), Gaps = 4/177 (2%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ ++ KDLIL+II +I V GA Y+++EF G TIE L+M++R +LCNM IEAG KNG+ Sbjct: 167 KLQEHVYGKDLILEIIRQIGVDGALYKALEFQGDTIEQLSMDDRFSLCNMAIEAGAKNGI 226 Query: 183 VPADETTFKYLEGKTSVEYEPVY--SDAQARFYSDYRFDVSKLEPVVAKPHSPDN-RALA 353 + AD T ++L + S+ EP Y +DA A + DV KLEPV+A P P N ++++ Sbjct: 227 IAADSITKEFLASRKSLRAEPKYYQADADALYEQTIEIDVEKLEPVIAYPFLPSNGKSIS 286 Query: 354 RECK-DVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVY 521 + K D+KID+ +IGSCT G+ D AA++ V + P TQ+++ D + Sbjct: 287 QAVKDDLKIDQAFIGSCTNGRLSDLRIAAQILKGKRVHPDVRLIITPGTQQIYKDAH 343
>LEU21_PYRAB (Q9UZ07) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 423 Score = 141 bits (355), Expect = 2e-33 Identities = 74/173 (42%), Positives = 112/173 (64%), Gaps = 4/173 (2%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ PY+ KDLIL IG+I V+GA Y+ MEF GS IE L++E+RMT+ NM IEAG K G+ Sbjct: 168 ELQPYVTGKDLILHTIGDIGVNGALYKVMEFSGSVIEELSVEQRMTMSNMAIEAGAKTGI 227 Query: 183 VPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRA-LARE 359 + D+ T Y++ + +++ SD A++Y +DV+ EPVVA PH P+N +++ Sbjct: 228 IEPDKKTLDYVKERAKRKFKVYKSDEDAKYYKVIEYDVTNWEPVVAFPHLPENTVPISKA 287 Query: 360 CK-DVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVK--VPTFLVPATQKVW 509 K ++KID+V+IGSCT G+ ED AA++ G+KV V ++P + V+ Sbjct: 288 AKMNIKIDQVFIGSCTNGRIEDLRMAAEIL--EGQKVAKWVRLIVIPCSPTVY 338
>LEU2_CLOAB (Q97EE0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 139 bits (350), Expect = 6e-33 Identities = 69/169 (40%), Positives = 104/169 (61%), Gaps = 2/169 (1%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ KD+IL IIG I V GA Y+SME+ G +E L+M++R T+ NM IEAG KNG+ P D Sbjct: 174 WVSGKDIILHIIGMIGVDGALYKSMEYTGDGLEYLSMDDRFTIANMAIEAGAKNGIFPVD 233 Query: 195 ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVK 374 E T +Y++G++ E + +D A + D+S L+P VA PH P+N + +V Sbjct: 234 EKTIEYMKGRSDRELKKFDADEDAEYSRVIEIDLSTLKPTVAFPHLPENTKTIDQVGEVN 293 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKVK--VPTFLVPATQKVWMD 515 +D+V IGSCT G+ ED AA + GKK+K + + P TQ ++++ Sbjct: 294 VDQVVIGSCTNGRMEDLRIAASIL--KGKKIKKGIRLIVFPGTQNIYLE 340
>LEU22_METTH (O27668) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 428 Score = 136 bits (343), Expect = 4e-32 Identities = 69/166 (41%), Positives = 99/166 (59%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ AKD+IL IIGEI V GATYRS+EF G TIES+ + RMT+CNM +E G KNG++ + Sbjct: 176 HVYAKDVILHIIGEIGVDGATYRSVEFTGDTIESMDVSGRMTICNMAVEMGAKNGIMEPN 235 Query: 195 ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVK 374 T Y+ +T E+ SD +++ D+ FDVS LEP VA P DN + Sbjct: 236 RQTLDYVRARTGREFRVYSSDEDSQYLEDHHFDVSDLEPQVACPDDVDNVYPVHRVEGTH 295 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWM 512 ID ++GSCT G+ ED AA+V V + PA++++++ Sbjct: 296 IDEAFLGSCTNGRYEDLKIAAEVIGDRRVHEDVRFIVSPASREIYL 341
>LEU22_ARCFU (O28084) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 416 Score = 135 bits (341), Expect = 6e-32 Identities = 70/172 (40%), Positives = 112/172 (65%), Gaps = 3/172 (1%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL++IG++ V GATY+++EF G E++T+EER+T+ NM +E G K G+ Sbjct: 164 LPKGVFAKDVILKLIGDLGVDGATYKALEFHGECAENMTVEERLTIANMAVECGAKAGIF 223 Query: 186 PADETTFKYL-EGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAREC 362 +DE T K+L E ++ V +D A + + DVS L PVV+KPH+ DN A E Sbjct: 224 ESDENTRKFLAELGREGDFREVKADEDAEYEKEIYMDVSSLVPVVSKPHNVDNVAEISEV 283 Query: 363 KDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVK--VPTFLVPATQKVWM 512 + ++++VYIG+CT G+ D AA++ G+KVK V +VPA+++V++ Sbjct: 284 EGTEVNQVYIGTCTNGRLSDLEVAARIL--KGRKVKEGVRLIVVPASRRVYL 333
>LEU2_HELHP (Q7VH31) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 420 Score = 133 bits (334), Expect = 4e-31 Identities = 62/171 (36%), Positives = 101/171 (59%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ PY+ KD+IL IIG+I V GA Y+SMEF G +++LT+++R+ + NM IEAG KNG+ Sbjct: 168 KLRPYVSGKDVILHIIGKIGVDGALYKSMEFGGEGLKNLTIDDRLCIANMAIEAGAKNGI 227 Query: 183 VPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAREC 362 D+ T Y +G+T ++ +D A + + D+ + VA PH P+N + Sbjct: 228 FEVDDITISYAKGRTKRDFRIYKADVDAEYEQVFDIDLDSINHTVAFPHLPENTKEKDDW 287 Query: 363 KDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMD 515 ++KID+V IGSCT G+ D AA++ ++PATQ ++++ Sbjct: 288 GEIKIDQVVIGSCTNGRLSDMAVAAEILKDKTIAKNTRCIIIPATQNIYLE 338
>LEU22_METJA (P81291) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 424 Score = 131 bits (329), Expect = 2e-30 Identities = 65/157 (41%), Positives = 94/157 (59%), Gaps = 5/157 (3%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ PY+ +KD+IL IIGE+ V GATY++ +F G T++ +++ RMT+ NM IE GGK G+ Sbjct: 167 DLQPYVTSKDVILSIIGEVGVDGATYKACQFGGETVKKMSIASRMTMTNMAIEMGGKTGI 226 Query: 183 VPADETTFKYLEGK-----TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRA 347 + DE T +Y++ T +E + D A F Y + K+EPV A PH+ DN Sbjct: 227 IEPDEKTIQYVKEAMKKHGTERPFEVIKGDEDAEFAEVYEIEADKIEPVFACPHNVDNVK 286 Query: 348 LARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASG 458 ARE ID+V+IGSCT G+ ED A K+ G Sbjct: 287 QAREVAGKPIDQVFIGSCTNGRLEDLRMAIKIIEKHG 323
>LEU22_METAC (Q8TQZ3) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 420 Score = 130 bits (326), Expect = 3e-30 Identities = 70/172 (40%), Positives = 105/172 (61%), Gaps = 2/172 (1%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + +KDLIL +IG++ V GA Y + E+ GSTI SL++ ERMT+ NM IE GGK G+ Sbjct: 167 KLPERVYSKDLILHLIGDVGVEGARYMAAEYAGSTIRSLSIPERMTISNMAIEMGGKAGI 226 Query: 183 VPADETTFKYLEGK-TSVEYEPVY-SDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAR 356 + ADE T YL+ + + +P + SD +A++ +DVS LEP VA PH+ DN Sbjct: 227 IEADEVTEAYLQERIPGYKLDPYWKSDEEAKYLDIRHYDVSDLEPQVACPHNVDNVKSVS 286 Query: 357 ECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWM 512 E + K+D+V++GSCT G+ ED A + V +VPA++ +M Sbjct: 287 EVEGTKLDQVFMGSCTNGRFEDIKIMADIMGDEPVAKGVRLLVVPASKTEYM 338
>LEU22_METMA (Q8PUG1) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 420 Score = 125 bits (315), Expect = 7e-29 Identities = 67/172 (38%), Positives = 102/172 (59%), Gaps = 2/172 (1%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + +KDLIL +IG++ V G Y + E+ GSTI SL++ ERMT+ NM IE GGK G+ Sbjct: 167 KLPERVYSKDLILHLIGDVGVEGVRYMAAEYAGSTIRSLSIPERMTMSNMAIEMGGKAGI 226 Query: 183 VPADETTFKYLEGK-TSVEYEPVYSDAQARFYSDYR-FDVSKLEPVVAKPHSPDNRALAR 356 + ADE T YL+ + + +P + + Y D R +DVS LEP VA PH+ DN Sbjct: 227 IEADEVTEAYLKERIPGFKLDPYWKSDEGAKYLDIRYYDVSDLEPQVACPHNVDNVKPVS 286 Query: 357 ECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWM 512 E + K+D++++GSCT G+ ED A + + +VPA++ +M Sbjct: 287 EVEGTKLDQIFMGSCTNGRFEDIKIMADIMGDEPVAKNLRLLVVPASKTEYM 338
>LEU22_THEMA (Q9WZ24) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 417 Score = 125 bits (315), Expect = 7e-29 Identities = 65/164 (39%), Positives = 97/164 (59%), Gaps = 2/164 (1%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKDL+L++I + V GA Y+++EF G ++ ++M+ R T+ NM IEAGGK G+ P DE T Sbjct: 172 AKDLVLKLISILGVDGANYKAIEFSGPGVKEISMDGRFTISNMAIEAGGKTGLFPVDEIT 231 Query: 204 FKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKD--VKI 377 Y E + +E E +Y D A++ + D+S+LEP VA P P N E + +KI Sbjct: 232 IAY-ERERGIEVEEMYPDEDAKYVREVEMDLSELEPQVAYPFLPSNAKDVSEAEKERIKI 290 Query: 378 DRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 D+ IGSCT G+ ED AA++ V ++P +QKV+ Sbjct: 291 DQAVIGSCTNGRIEDLRLAAQILKGRTVSPDVRCIIIPGSQKVY 334
>LEU22_DEIRA (Q9RTI6) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 431 Score = 123 bits (309), Expect = 3e-28 Identities = 67/170 (39%), Positives = 98/170 (57%), Gaps = 4/170 (2%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + KD++L++I +I GA Y ME+VG I+ L ME R TL NM IEAGGK G+V Sbjct: 171 PGVTPKDIVLEVIKQIGADGANYMVMEWVGDYIDQLDMEGRFTLTNMAIEAGGKTGIVAV 230 Query: 192 DETTFKYLE--GKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECK 365 D+TT Y++ G + +Y SD A++ D +++EP VA PH P N +A + Sbjct: 231 DDTTRAYMQQRGVSPEQYTEYQSDPDAKYKVVVEIDAAQVEPTVAYPHIPSNGRVAGSDR 290 Query: 366 DVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKV--KVPTFLVPATQKVW 509 +++ Y+GSCT G+ D A++ G+KV V +VPATQ +W Sbjct: 291 -IRVTHAYVGSCTNGRITDLRDVARIL--KGRKVAQDVQMIVVPATQAIW 337
>LEU2_THETN (Q8RDK2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 418 Score = 123 bits (308), Expect = 4e-28 Identities = 68/169 (40%), Positives = 101/169 (59%), Gaps = 2/169 (1%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ KD+IL IIG+I V GA Y+SMEF G+ I++L++++R T+ NM IEAG KNG+ D Sbjct: 171 WVSGKDVILYIIGKIGVDGALYKSMEFTGN-IKALSIDDRFTIANMAIEAGAKNGIFDFD 229 Query: 195 ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVK 374 E T Y++ + EY+ D A + ++ + P VA PH P+N E VK Sbjct: 230 EITEAYVKKRAKREYKVFERDEDAEYSEVIEINLDDIRPQVAFPHLPENTRSIDEVGKVK 289 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKV--KVPTFLVPATQKVWMD 515 ID+V IGSCT G+ D A ++ GKKV V + PATQ+++++ Sbjct: 290 IDQVVIGSCTNGRLSDMEIAYRIL--KGKKVHPDVRLIIFPATQEIYLE 336
>LEU21_METTH (O27439) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 419 Score = 122 bits (306), Expect = 7e-28 Identities = 63/165 (38%), Positives = 93/165 (56%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ AKD+IL IIG + GATY + EF G T+ +++ +RM L NM IE GGK G+V D Sbjct: 171 HVYAKDVILNIIGRVGADGATYMACEFAGETVAEMSVSDRMVLSNMAIEMGGKTGIVEPD 230 Query: 195 ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVK 374 E T Y+ ++ + +D A S DVS LEP VA PH+ DN E + + Sbjct: 231 EKTLNYVRRRSGKPWRVFKTDPDAPSLSVMEVDVSDLEPQVACPHNVDNVKPVTEVEGTE 290 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 ID+V++GSCT G+ D AA + V ++PA+++V+ Sbjct: 291 IDQVFLGSCTNGRLSDLRDAAAILKNRKVSDSVRMLVIPASREVY 335
>LEU21_THEMA (Q9WYC7) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 122 bits (306), Expect = 7e-28 Identities = 64/167 (38%), Positives = 105/167 (62%), Gaps = 3/167 (1%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL+I + GATY+++EF GS IE++ +E+R+T+ NM +E G K G++P+DE T Sbjct: 170 AKDIILEIARILGSDGATYKALEFHGSCIENMNVEDRLTISNMAVEVGAKAGLMPSDEKT 229 Query: 204 FKYLEGKTSVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDN--RALARECKDVK 374 ++L+ E + + +D A + ++ D + LEP+V+ PH DN + E + +K Sbjct: 230 REFLKKMGREEDFRELKADPDAVYETEIEIDATTLEPLVSLPHYVDNVRKVSEVEKEKIK 289 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMD 515 ID+V+IG+CT G+ +D A K+ GK V + PA++KV+MD Sbjct: 290 IDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMD 336
>LEU21_METJA (Q58409) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 420 Score = 121 bits (304), Expect = 1e-27 Identities = 61/172 (35%), Positives = 100/172 (58%), Gaps = 9/172 (5%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD++L++ EI GATY ++E+ G ++++ M+ R+TLCNM IE GGK GV+ ADE T Sbjct: 168 AKDIVLRVCKEIGRRGATYMAIEYGGEVVKNMDMDGRLTLCNMAIEMGGKTGVIEADEIT 227 Query: 204 FKYLEGKTSVEYEPV---------YSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAR 356 + YL+ + + E + + +A +Y + D++ +E VA PH PDN Sbjct: 228 YDYLKKERGLSDEDIAKLKKERITVNRDEANYYKEIEIDITDMEEQVAVPHHPDNVKPIS 287 Query: 357 ECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWM 512 + + +I++V+IGSCT G+ D AAK V ++PA++KV++ Sbjct: 288 DVEGTEINQVFIGSCTNGRLSDLREAAKYLKGREVHKDVKLIVIPASKKVFL 339
>LEU21_ARCFU (O28316) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 418 Score = 119 bits (299), Expect = 5e-27 Identities = 61/168 (36%), Positives = 97/168 (57%), Gaps = 1/168 (0%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ ++ KD++L++IG + GA Y++ + G +E L M +R+T+CNM IE GGK G+ Sbjct: 166 KLEKHVYGKDIVLKLIGMVGADGANYKACIYSGEVVEKLGMSDRLTMCNMAIEMGGKAGI 225 Query: 183 VPADETTFKYLEGK-TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARE 359 V D+TT +YL+ E E + SD A F + DV+ +EP VA PH DN E Sbjct: 226 VEPDKTTLEYLKAMGRPYEGELLKSDEDAEF-QEVELDVTGMEPQVAAPHRVDNVVGISE 284 Query: 360 CKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQK 503 + ++D+V+IGSCT G+ ED AA++ V ++PA+ + Sbjct: 285 VEGTRVDQVFIGSCTNGRYEDLKIAAEILKGEKVASNVRLIVIPASHR 332
>LEU2_PICTO (Q6L0K5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 413 Score = 115 bits (289), Expect = 7e-26 Identities = 65/161 (40%), Positives = 91/161 (56%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL ++ I G+ Y+ MEF GSTI+ L + ERMT+ NM EAG K ADE T Sbjct: 171 KDIILNVLSRIGNGGSAYKCMEFTGSTIDYLDINERMTMANMTTEAGAKCSFFNADEKTL 230 Query: 207 KYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVKIDRV 386 Y+ KT+ +Y+ D A + D S++EP VA P+SPDN + + +ID+ Sbjct: 231 DYIRNKTN-DYKIYKDDENAEYSRIIDIDASEIEPSVAIPNSPDNVRPVSKVSE-RIDQA 288 Query: 387 YIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 YIGSCT G+ ED AA + V +VPA+Q+V+ Sbjct: 289 YIGSCTNGRIEDIRRAALILKDKKIDKNVRLMVVPASQEVY 329
>LEU2_RHIME (Q92L76) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 113 bits (282), Expect = 4e-25 Identities = 80/223 (35%), Positives = 113/223 (50%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++PP + AKD+IL IIGEI +G T +EF G I SL+ME RMT+CNM IE G + G+ Sbjct: 176 QLPPGVTAKDIILAIIGEIGTAGGTGHVIEFAGEAIRSLSMEGRMTVCNMTIEGGARAGL 235 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+Y++ K +VEY + +++D A + D + L P+V+ Sbjct: 236 IAPDETTFEYIKDKPRAPKGEAWDRAVEYWKTLHTDEGAHYDRVVVLDAANLPPIVSWGS 295 Query: 330 SPDN------------------------RAL-------ARECKDVKIDRVYIGSCTGGKT 416 SP++ RAL + D+ IDRV+IGSCT G+ Sbjct: 296 SPEDVVSVQGVVPNPDDIQDETKRTSKWRALDYMGLKPGTKITDIAIDRVFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED A A+V G+KV PT V ++ VPGSG Sbjct: 356 EDLRAVAEV--VEGRKV-APT------------VSAMIVPGSG 383
>LEU2_BRUSU (Q8FYG9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 113 bits (282), Expect = 4e-25 Identities = 78/223 (34%), Positives = 110/223 (49%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD++L IIGEI +G T +E+ G I SL+ME RMT+CNM IE G + G+ Sbjct: 176 KLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGL 235 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+Y++G+ ++ ++SD A F D L P+V+ Sbjct: 236 IAPDETTFEYIKGRPRAPQGETLEQAINYWKTLHSDEGAHFDKIVTLDAGSLPPIVSWGS 295 Query: 330 SPDN------------------------RAL-------ARECKDVKIDRVYIGSCTGGKT 416 SP++ RAL + D+ +DRV+IGSCT G+ Sbjct: 296 SPEDVVSVTGVVPNPDDIADETKRASKWRALDYMGLKPGTKITDIAVDRVFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAAKV GKKV PT V ++ VPGSG Sbjct: 356 EDLRAAAKV--VEGKKV-APT------------VNAMIVPGSG 383
>LEU2_BRUME (Q8YJC9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 113 bits (282), Expect = 4e-25 Identities = 78/223 (34%), Positives = 110/223 (49%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD++L IIGEI +G T +E+ G I SL+ME RMT+CNM IE G + G+ Sbjct: 176 KLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGL 235 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+Y++G+ ++ ++SD A F D L P+V+ Sbjct: 236 IAPDETTFEYIKGRPRAPQGETLEQAINYWKTLHSDEGAHFDKIVTLDAGSLPPIVSWGS 295 Query: 330 SPDN------------------------RAL-------ARECKDVKIDRVYIGSCTGGKT 416 SP++ RAL + D+ +DRV+IGSCT G+ Sbjct: 296 SPEDVVSVTGVVPNPDDIADETKRASKWRALDYMGLKPGTKITDIAVDRVFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAAKV GKKV PT V ++ VPGSG Sbjct: 356 EDLRAAAKV--VEGKKV-APT------------VNAMIVPGSG 383
>LEU2_SYMTH (Q67MJ2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 112 bits (280), Expect = 7e-25 Identities = 78/212 (36%), Positives = 105/212 (49%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++PP AKDLIL IIG+I GAT +E+ G I SL+ME RMT+CNM IEAG + G+ Sbjct: 181 KLPPGTTAKDLILGIIGQIGTDGATGYVIEYTGEAIRSLSMEGRMTVCNMSIEAGARAGM 240 Query: 183 VPADETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVA--- 320 + DETTF YL+G+ ++ + SD A + FD +L PVV+ Sbjct: 241 IAPDETTFAYLKGRPHAPQGELWEAAVADWRTLASDPDAVYDRVVEFDAGQLAPVVSWGT 300 Query: 321 --------KPHSPDNRALA--------------------RECKDVKIDRVYIGSCTGGKT 416 PD R A +D++IDRV+IGSCT G+ Sbjct: 301 NPGQVVPVTGRIPDPRDFADPAQRKAAEAALAYMDLEPGTPIQDIRIDRVFIGSCTNGRI 360 Query: 417 EDFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 ED AAA V G+KV V +VP + +V Sbjct: 361 EDLRAAAAV--VKGRKVAPGVRAMVVPGSGQV 390
>LEU2_NITWN (Q3SNV3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 112 bits (280), Expect = 7e-25 Identities = 76/223 (34%), Positives = 110/223 (49%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL IIGEI +G T +E+ G I +L+ME RMT+CNM IE G + G+ Sbjct: 175 KLPDGVTAKDIILAIIGEIGTAGGTGYVLEYAGEAIRALSMEGRMTVCNMSIEGGARAGL 234 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DET +++L+G+ +E + SD A F + R D +KL P+V Sbjct: 235 IAPDETAYEFLKGRPKAPKGADWDAALRYWETLRSDDGAHFDHEIRLDAAKLPPIVTWGT 294 Query: 330 S-----------PDNRALARECK--------------------DVKIDRVYIGSCTGGKT 416 S PD A+ E K D+++DRV+IGSCT G+ Sbjct: 295 SPEDVIAVTGKVPDPAAIEDEAKRLSKERALHYMGLLPGTKITDIRLDRVFIGSCTNGRI 354 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAAK+ A G+ V +V ++ VPGSG Sbjct: 355 EDLRAAAKI--AEGRTVN-------------GNVSAMVVPGSG 382
>LEU2_RHILO (Q98EF1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 111 bits (278), Expect = 1e-24 Identities = 72/207 (34%), Positives = 102/207 (49%), Gaps = 42/207 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL IIGEI +G T +E+ G I SL+ME RMT+CNM IE G + G+ Sbjct: 176 QLPEGVTAKDIILAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGL 235 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + ADETTF Y++ K ++ + SD A F D +KL P+V+ Sbjct: 236 IAADETTFAYVKDKPRAPKGAAWDAALAYWKTLQSDEGAHFDKVIVLDAAKLPPIVSWGS 295 Query: 330 SPDN------------------------RAL-------ARECKDVKIDRVYIGSCTGGKT 416 SP++ RAL + D+ +DRV+IGSCT G+ Sbjct: 296 SPEDVVSVQGVVPNPEEITDENKRTSKIRALDYMGLTPGTKITDIALDRVFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPAT 497 ED AAAKV +V +VP + Sbjct: 356 EDLRAAAKVIEGKTVNPRVNAMIVPGS 382
>LEU2_RHOPA (Q6ND69) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 109 bits (273), Expect = 5e-24 Identities = 76/223 (34%), Positives = 110/223 (49%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL IIGEI +G T +E+ G I SL+ME RMT+CNM IE G + G+ Sbjct: 176 QLPDGVTAKDVILAIIGEIGTAGGTGYVLEYAGDAIRSLSMEGRMTVCNMSIEGGARAGL 235 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE +++L+G+ ++ + SD A F + + D + L P+V Sbjct: 236 IAPDERAYEFLKGRPLAPKGAAWDAALRYWDTLRSDDGAHFDHELKLDAAALPPIVTWGT 295 Query: 330 SPDN------------------------RALA-------RECKDVKIDRVYIGSCTGGKT 416 SP++ RALA + D+KIDR++IGSCT G+ Sbjct: 296 SPEDVISVTGRVPNPADIADEAKRLSKERALAYMGLTPGTKITDIKIDRMFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAAKV A GK V +V ++ VPGSG Sbjct: 356 EDLRAAAKV--AEGKTVNA-------------NVNAIIVPGSG 383
>LEU2_AGRT5 (Q8UBY9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 108 bits (269), Expect = 1e-23 Identities = 73/209 (34%), Positives = 102/209 (48%), Gaps = 44/209 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL IIGEI +G T +EF G I SL+ME RMT+CNM IE G + G+ Sbjct: 176 KLPESVTAKDIILAIIGEIGTAGGTGHVIEFAGEAIRSLSMEGRMTVCNMTIEGGARAGL 235 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF Y++ K ++ + SD A + D + L P+V+ Sbjct: 236 IAPDETTFDYIKDKPRAPKGETLEQAIAYWKTLKSDEGAHYDKVVILDAANLPPIVSWGS 295 Query: 330 SPDN------------------------RAL-------ARECKDVKIDRVYIGSCTGGKT 416 SP++ RAL D+ IDRV+IGSCT G+ Sbjct: 296 SPEDVTSVEGIVPNPDDIEEENKRTSKWRALDYMGLKPGTRITDIAIDRVFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKV--KVPTFLVPAT 497 ED AAAK+ G+KV V +VP + Sbjct: 356 EDLRAAAKI--VDGRKVASTVSAMIVPGS 382
>LEU2_BUCRP (P48573) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 108 bits (269), Expect = 1e-23 Identities = 72/222 (32%), Positives = 111/222 (50%), Gaps = 42/222 (18%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ AKD+IL IIG++ SG + +EF G I+ + MEERMT+CNM IE G K+ ++ D Sbjct: 177 FVTAKDIILFIIGKLGTSGGSGYVIEFCGDVIKKMNMEERMTVCNMAIEMGAKSALIAPD 236 Query: 195 ETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD- 338 ETTF YL+G+ +V+Y + + + ++A F ++ FDVS L P + SPD Sbjct: 237 ETTFLYLKGRRYSPQGKFWEEAVKYWKTLITRSKAFFDKEFTFDVSNLSPQITWGTSPDQ 296 Query: 339 ------------------NRALAREC------------KDVKIDRVYIGSCTGGKTEDFI 428 + LAR D+KID+V+IGSCT + ED Sbjct: 297 VLSINEKIPDFNFFKDSVKKNLARSACDYMNLKPGSYLTDIKIDKVFIGSCTNSRIEDLR 356 Query: 429 AAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSGGKT 554 +AAK+ +K+ ++ ++ +PGSG T Sbjct: 357 SAAKIL---------------KNKKISKNIKAILLPGSGTGT 383
>LEU22_BRAJA (Q89X34) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 468 Score = 107 bits (267), Expect = 2e-23 Identities = 75/223 (33%), Positives = 105/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + KD+IL IIGEI +G T +E+ G I +L+ME RMT+CNM IE G + G+ Sbjct: 175 KLPDGVTGKDIILAIIGEIGTAGGTGYVLEYAGEAIRALSMEGRMTVCNMSIEGGARAGL 234 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+ + +L + +E + SD A F + R D +KL P+V Sbjct: 235 VAPDQKAYDFLRDRPKAPKGAAWDAAMRYWEKLRSDDGAHFDHELRLDAAKLPPIVTWGT 294 Query: 330 S-----------PDNRALARECK--------------------DVKIDRVYIGSCTGGKT 416 S PD +A E K D+K+DRV+IGSCT G+ Sbjct: 295 SPEDVISVTGIVPDPDKIADEAKRLSKHRALKYMGLTAGTKITDIKLDRVFIGSCTNGRI 354 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAAK+ A GK+V V ++ VPGSG Sbjct: 355 EDLRAAAKI--AEGKQVSA-------------SVNAMVVPGSG 382
>LEU2_BUCTS (O31293) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 106 bits (265), Expect = 4e-23 Identities = 72/211 (34%), Positives = 110/211 (52%), Gaps = 44/211 (20%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 + PY+ AKD+IL II ++ + T +EF G TIE+LTME RMT+CNMVIE G K+G++ Sbjct: 174 LKPYITAKDVILYIIKKVGTAFGTGYVVEFSGETIENLTMEGRMTICNMVIEMGAKSGII 233 Query: 186 PADETTFKYLEG----------KTSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 D TT+KYL+ K ++EY + + +D A+F +FDVS++EP + + Sbjct: 234 APDATTYKYLKNLPYAPKKEKWKNALEYWKNLKTDNDAKFDKIVKFDVSQIEPQITWGTN 293 Query: 333 P--------------------DNRALARECK-----------DVKIDRVYIGSCTGGKTE 419 P D +A + K ++ +D+V+IGSCT + E Sbjct: 294 PSQTINITESNPDPKKINNIIDKQATEKALKYMNLKPNQKMINLVVDKVFIGSCTNSRIE 353 Query: 420 DFIAAAKVFLASGKKVKVPT--FLVPATQKV 506 D A+K+ KKV T +VP ++ V Sbjct: 354 DLRIASKII--KNKKVAKTTKAIVVPGSKLV 382
>LEU2_PSEPK (Q88LE8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 106 bits (265), Expect = 4e-23 Identities = 71/197 (36%), Positives = 103/197 (52%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD++L +IG+I +G +MEF GS I L+ME RMT+CNM IEAG + G+ Sbjct: 178 QLPAGVTAKDIVLAVIGKIGTAGGNGHAMEFAGSAIRELSMEGRMTICNMSIEAGARVGL 237 Query: 183 VPADETTFKYLEG----------KTSVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D TT Y+EG K +VE ++ + SD A F + D S+++P V+ Sbjct: 238 VATDATTVAYVEGRPYAPKGEQWKQAVESWKDLVSDDDAVFDTVVELDASQIKPQVSWGT 297 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL + D+K+DRV+IGSCT + Sbjct: 298 SPEMVLAVDQRVPDPAAETDLVKRGSIERALKYMGLTANQAITDIKLDRVFIGSCTNSRI 357 Query: 417 EDFIAAAKVFLASGKKV 467 ED AAA++ A G+KV Sbjct: 358 EDLRAAAEI--AKGRKV 372
>LEU2_SULAC (Q4JC09) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 414 Score = 106 bits (264), Expect = 5e-23 Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 2/173 (1%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ KD+ L+I+G+ S+E ++ M+ R T+ NM IE + D Sbjct: 169 WINGKDIALKILGDFKADYFNGMSLEIFVKEPSAVPMDFRATVSNMGIEMNADALMFVPD 228 Query: 195 ETTFKYLEGKTSVEYEP--VYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKD 368 + TF Y+ KT+ YEP V D+ A++ +Y D+SKL+P+VA PHS DN E + Sbjct: 229 QETFNYI--KTARGYEPQMVTPDSDAKYVDEYNIDLSKLDPLVAAPHSVDNVKSVNEVEG 286 Query: 369 VKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSL 527 +D+V+IGSCT G+ D AAK+ GKKVK T ++PA+ +++ L Sbjct: 287 TPVDQVFIGSCTNGRISDLEMAAKIL--KGKKVKTRTIVIPASYQLFKKALEL 337
>LEU2_BUCUL (Q9AQC6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 369 Score = 105 bits (263), Expect = 7e-23 Identities = 71/223 (31%), Positives = 107/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P ++ AKD+IL +IG + SG T +EF G+ I+ ++MEERMT+CNM IE G K+G+ Sbjct: 100 DVPQFVTAKDIILFVIGRLGSSGGTGYVIEFCGNVIKKMSMEERMTVCNMAIEMGAKSGI 159 Query: 183 VPADETTFKYLE----------GKTSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T+ YL K S++Y + + SD A F + DVS L P V + Sbjct: 160 IAPDEITYSYLREKIYSPYGLFWKKSIDYWKTLKSDKDAFFDKCFTIDVSNLAPQVTRGT 219 Query: 330 SPDNRALARE--------------------CK-----------DVKIDRVYIGSCTGGKT 416 +PD E CK D+ ID+V+IGSCT + Sbjct: 220 NPDQVTSINEKIPNYNKFHSIVQKNSAKSACKYMGLKEGTYLTDIFIDKVFIGSCTNARI 279 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +A+ + +K+ +V ++ VPGSG Sbjct: 280 EDLRSASTIL---------------KNRKIANNVKAIVVPGSG 307
>LEU2_STAHJ (Q4L7U2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 105 bits (263), Expect = 7e-23 Identities = 63/207 (30%), Positives = 104/207 (50%), Gaps = 32/207 (15%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL +I + V T ++EF G TI SL+ME RMT+CNM IEAG K G+ Sbjct: 172 QLPKGVYAKDIILYLISQYGVDFGTGYAIEFTGETIRSLSMEARMTICNMAIEAGAKYGL 231 Query: 183 VPADETTFKYLEGKTSV--------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP- 335 + DE TF Y++ + ++ +Y+DA A+F + DV+ LEP V +P Sbjct: 232 MQPDEMTFAYVKDRKYARNFDRSINDWRQLYTDADAKFDKVIKLDVTNLEPQVTWGTNPE 291 Query: 336 ----------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVF 446 D RA ++ +D+ + V++GSCT + D + A+++ Sbjct: 292 MGVSFNTPFPKIKNINDERAYQYMGLKPGQKAEDIDLGYVFLGSCTNARLSDLVEASRIV 351 Query: 447 LASGKKVKVPTFLVPATQKVWMDVYSL 527 K+ +VP ++ V + +L Sbjct: 352 KGKQVHPKITAIVVPGSRSVKKEAEAL 378
>LEU2_STAES (Q8CNL1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 105 bits (263), Expect = 7e-23 Identities = 65/206 (31%), Positives = 103/206 (50%), Gaps = 32/206 (15%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I + V T ++EF G TI++L+ME RMT+CNM IEAG K G++ Sbjct: 173 LPAGVYAKDIILYLINQYGVDFGTGYALEFTGETIKNLSMEARMTICNMAIEAGAKYGLM 232 Query: 186 PADETTFKYLEGK--------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 DETTF Y++G+ + ++ +YSD A F DV+ LEP V +P Sbjct: 233 QPDETTFNYVKGRPYATDFDSSMAWWKELYSDDDAYFDKVIELDVTNLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+K+ V++GSCT + D I A+ + Sbjct: 293 GVSFSNPFPEIKNANDQRAYDYMGLHPGQKAEDIKLGYVFLGSCTNARLSDLIEASHIIK 352 Query: 450 ASGKKVKVPTFLVPATQKVWMDVYSL 527 + +VP ++ V + +L Sbjct: 353 GQQVHPNITAIVVPGSRTVKKEAEAL 378
>LEU2_STAEQ (Q5HMF7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 105 bits (263), Expect = 7e-23 Identities = 65/206 (31%), Positives = 103/206 (50%), Gaps = 32/206 (15%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I + V T ++EF G TI++L+ME RMT+CNM IEAG K G++ Sbjct: 173 LPAGVYAKDIILYLINQYGVDFGTGYALEFTGETIKNLSMEARMTICNMAIEAGAKYGLM 232 Query: 186 PADETTFKYLEGK--------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 DETTF Y++G+ + ++ +YSD A F DV+ LEP V +P Sbjct: 233 QPDETTFNYVKGRPYATDFDSSMAWWKELYSDDDAYFDKVIELDVTNLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+K+ V++GSCT + D I A+ + Sbjct: 293 GVSFSNPFPEIKNANDQRAYDYMGLHPGQKAEDIKLGYVFLGSCTNARLSDLIEASHIIK 352 Query: 450 ASGKKVKVPTFLVPATQKVWMDVYSL 527 + +VP ++ V + +L Sbjct: 353 GQQVHPNITAIVVPGSRTVKKEAEAL 378
>LEU2_BUCUS (Q9EVI3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 105 bits (262), Expect = 9e-23 Identities = 69/210 (32%), Positives = 104/210 (49%), Gaps = 42/210 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P ++ AKD+IL IIG++ S T +EF G I++++MEERMT+CNM IE G K+G+ Sbjct: 173 EIPKFVTAKDIILFIIGKLGSSSGTGYVIEFCGDVIKNMSMEERMTICNMAIEMGAKSGL 232 Query: 183 VPADETTFKYLEGK----TSVEYEP-------VYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T+KYL+ K + + +E + SD A F D+S L P + Sbjct: 233 IAPDEITYKYLKNKIYSPSGLSWEKSLDHWKFLKSDKNAYFDKCVTVDISNLAPQITWGT 292 Query: 330 SPD---------------NRALARECK----------------DVKIDRVYIGSCTGGKT 416 +PD N A+ RE ++ IDRV+IGSCT + Sbjct: 293 NPDQVISIDEKIPDYNNINSAIKRESSKSACEYMGLQSNTYLTNISIDRVFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKV 506 ED +A+K+ V +VP ++ V Sbjct: 353 EDLRSASKILKNKKIAKHVKAIVVPGSKLV 382
>LEU2_BUCUM (Q9EVG8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 444 Score = 105 bits (261), Expect = 1e-22 Identities = 73/223 (32%), Positives = 110/223 (49%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P ++ AKD+IL IIG++ S T +EF G I++++MEERMT+CNM IE G K+G+ Sbjct: 174 KIPKFVTAKDIILFIIGQLGSSSGTGYVIEFCGDVIKNISMEERMTICNMAIEMGAKSGL 233 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T+KYL+ K S++Y + + SD A F D+S L P + Sbjct: 234 IAPDEITYKYLKDKIYSPSGLFWEKSLDYWKFLKSDKNAHFDKCITLDISNLAPQITWGT 293 Query: 330 SPD---------------NRALARE-----CK-----------DVKIDRVYIGSCTGGKT 416 +PD N L +E C+ ++ IDRV+IGSCT + Sbjct: 294 NPDQVISIDEKIPDYNNINSLLKKESAKSACEYMGLKSNTYLTNISIDRVFIGSCTNARI 353 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AA+K+ +K+ V ++ VPGSG Sbjct: 354 EDLRAASKIL---------------KNRKIAKHVKAIVVPGSG 381
>LEU2_BUCAP (O85065) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 104 bits (260), Expect = 2e-22 Identities = 68/219 (31%), Positives = 107/219 (48%), Gaps = 42/219 (19%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ AKD+IL IIG++ S + +EF G I+ + MEERMT+CNM IE G K+ ++ D Sbjct: 177 FITAKDIILFIIGKLGTSSGSGYVIEFCGDVIKKMNMEERMTICNMAIEMGAKSALIAPD 236 Query: 195 ETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD- 338 ETT+ YL+ K +++ Y + + +D A F ++ FD+S + P V SPD Sbjct: 237 ETTYLYLKNKRYSPKNKYWDSAIRYWKTLVTDENALFDKEFTFDISDISPQVTWGTSPDQ 296 Query: 339 ------------------NRALAREC------------KDVKIDRVYIGSCTGGKTEDFI 428 + LAR K++KID+V+IGSCT + ED Sbjct: 297 VLSINEKIPDFNSFKDSIKKDLARSACNYMDLKPGSYLKNIKIDKVFIGSCTNSRIEDLR 356 Query: 429 AAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 +AA + +K+ ++ ++ VPGSG Sbjct: 357 SAATIL---------------KNKKISKNIKAIVVPGSG 380
>LEU2_BUCUE (Q9EVH4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 104 bits (260), Expect = 2e-22 Identities = 69/223 (30%), Positives = 104/223 (46%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P ++ AKD+IL IIG++ S T +EF G I +++MEERMTLCNM IE G K+G+ Sbjct: 173 KVPEFITAKDIILFIIGQLGSSRGTGYVIEFFGDVINNMSMEERMTLCNMAIEMGAKSGL 232 Query: 183 VPADETTFKYLEGKTSVEY-----------EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T+ YL+ K Y + SD A F + D+S L P + Sbjct: 233 IAPDEITYSYLKNKIYSPYGIFWKKAIDYWSTLKSDKNAYFDKFFTIDISNLAPQITWGT 292 Query: 330 SPD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKT 416 +PD ++ CK DV +D+V+IGSCT + Sbjct: 293 NPDQVISIDEKIPNHNKFDSSIIRDSIKSACKYMGLKEGTYLTDVSVDKVFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +A+K+ +K+ +V ++ VPGSG Sbjct: 353 EDLRSASKIL---------------KNKKISKNVKAIVVPGSG 380
>LEU2_STAS1 (Q49Z14) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 104 bits (260), Expect = 2e-22 Identities = 66/207 (31%), Positives = 106/207 (51%), Gaps = 32/207 (15%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL +I + V T ++EF G TI SL+ME RMT+CNM IEAG K G+ Sbjct: 172 KLPTGVYAKDIILHLINQHGVDFGTGYALEFSGETIRSLSMEARMTICNMAIEAGAKYGM 231 Query: 183 VPADETTFKYLEGK---TSVEYE-----PVYSDAQARFYSDYRFDVSKLEPVVAKPHSP- 335 + DETTF+Y++G+ T+ +Y+ +Y+D A F DV+ LEP V +P Sbjct: 232 MAPDETTFEYVKGRPYATNYKYDIDAWRELYTDEDAEFDRVITLDVTDLEPQVTWGTNPE 291 Query: 336 ----------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVF 446 D RA ++ +D+ + V++GSCT + D + A+ V Sbjct: 292 MGVSFNTPFPEIQNVNDERAYNYMGLQPGQKAEDIDLGYVFLGSCTNARLSDLVEASHVV 351 Query: 447 LASGKKVKVPTFLVPATQKVWMDVYSL 527 + + +VP ++ V ++ L Sbjct: 352 KGNKVHPNITAIVVPGSRTVKIEAEKL 378
>LEU2_BUCUH (Q9EVH7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 104 bits (259), Expect = 2e-22 Identities = 70/223 (31%), Positives = 105/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P ++ AKD+IL II + SG + +EF G+ IE ++MEERMT+CNM IE G K+G+ Sbjct: 173 DIPKFVTAKDIILFIIRRLGSSGGSGYVIEFCGNVIEKMSMEERMTVCNMAIEMGAKSGI 232 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETT+ YL+ K S+ Y + + SD A F + D+S L P V Sbjct: 233 IAPDETTYAYLKNKIYSPSGACWEXSISYWKTLKSDKDAFFDKCFTIDISNLAPQVTWGT 292 Query: 330 SPDNRALARE-------------------------------CKDVKIDRVYIGSCTGGKT 416 SPD E ++ ID+V+IGSCT + Sbjct: 293 SPDQVISINEKIPHYNEFNSITQKNSAKSALKYMGLNEGAYLTNISIDKVFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +A+K+ +K+ +V ++ VPGSG Sbjct: 353 EDLRSASKIL---------------KNRKISSNVKAIVVPGSG 380
>LEU2_BURMA (Q62AI6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 103 bits (258), Expect = 3e-22 Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P AKD++L IIG+I +G T ++EF GSTI +LTME RMT+CNM IEAG + G+ Sbjct: 173 QLPRGCTAKDIVLAIIGQIGTAGGTGYAIEFGGSTIRALTMEGRMTVCNMAIEAGARAGM 232 Query: 183 VPADETTFKYLEGK----------TSVEYEPVY-SDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+TT +YL+G+ +VEY + SD A+F D +++ P V Sbjct: 233 VAVDDTTVEYLKGRPFVPTGAEWDQAVEYWKTFRSDEGAQFDRVVELDAAQIVPQVTWGT 292 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RALA + +K+D+++IGSCT + Sbjct: 293 SPEMVTSIDGRVPDPEREKDPVKRDAMERALAYMALAPNTPIEAIKVDKIFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA V ++V L ++ VPGSG Sbjct: 353 EDIRAAAYVVKKLNRRVAPNVRL------------AMVVPGSG 383
>LEU2_BUCDN (O85072) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 103 bits (257), Expect = 3e-22 Identities = 68/203 (33%), Positives = 104/203 (51%), Gaps = 42/203 (20%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ AKD+IL IIG+I S T +EF G+ I+ ++MEERMT+CNM IE G K+G++ D Sbjct: 177 FITAKDVILYIIGKIGSSAGTGYIIEFCGNVIKKMSMEERMTVCNMAIELGAKSGLIAPD 236 Query: 195 ETTFKYLEGKT----------SVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD- 338 ETT+ YL+ KT ++EY + + +D A F + D+S + P V +PD Sbjct: 237 ETTYLYLKNKTYSPHGRNWQKAIEYWKTLKTDHNAIFDKVFTIDISNILPQVTWGTNPDQ 296 Query: 339 ------------------NRALARE-CK-----------DVKIDRVYIGSCTGGKTEDFI 428 + LA+ CK D+ ID+V+IGSCT + ED Sbjct: 297 VIGINEKIPDFTSFQNIVKKDLAKSACKYMDLKPGTYLTDITIDKVFIGSCTNSRIEDLR 356 Query: 429 AAAKVFLASGKKVKVPTFLVPAT 497 +A+K+ + V +VP + Sbjct: 357 SASKILKHNKISKNVKAIVVPGS 379
>LEU2_YERPS (Q66EM3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 103 bits (257), Expect = 3e-22 Identities = 77/218 (35%), Positives = 107/218 (49%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ +G T +EF GS IE+L+ME RMTLCNM IE G K G+V D+ Sbjct: 184 ITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMAIEMGAKAGLVAPDD 243 Query: 198 TTFKYLEGK----TSVEYE-------PVYSDAQARFYSDYRFDVSKLEP----------- 311 TTF YL+G+ T ++E + SDA A+F + D + + P Sbjct: 244 TTFAYLKGRQFAPTGEQWEQGVAYWRTLKSDADAQFDTIVTLDAADIAPQVTWGTNPGQV 303 Query: 312 -----VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIA 431 ++ P S P RA A + +V ID+V+IGSCT + ED A Sbjct: 304 IAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDKVFIGSCTNSRIEDLRA 363 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AA + A G+KV V ++ VPGSG Sbjct: 364 AAAI--AQGRKVA-------------KGVQAIVVPGSG 386
>LEU2_YERPE (Q8ZIH0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 103 bits (257), Expect = 3e-22 Identities = 77/218 (35%), Positives = 107/218 (49%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ +G T +EF GS IE+L+ME RMTLCNM IE G K G+V D+ Sbjct: 184 ITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMAIEMGAKAGLVAPDD 243 Query: 198 TTFKYLEGK----TSVEYE-------PVYSDAQARFYSDYRFDVSKLEP----------- 311 TTF YL+G+ T ++E + SDA A+F + D + + P Sbjct: 244 TTFAYLKGRQFAPTGEQWEQGVAYWRTLKSDADAQFDTIVTLDAADIAPQVTWGTNPGQV 303 Query: 312 -----VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIA 431 ++ P S P RA A + +V ID+V+IGSCT + ED A Sbjct: 304 IAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDKVFIGSCTNSRIEDLRA 363 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AA + A G+KV V ++ VPGSG Sbjct: 364 AAAI--AQGRKVA-------------KGVQAIVVPGSG 386
>LEU2_THEFY (Q47SA3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 103 bits (257), Expect = 3e-22 Identities = 74/212 (34%), Positives = 108/212 (50%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + AKD+IL +I +I G +E+ G I SL+ME RMT+CNM IEAG + G+ Sbjct: 173 KLKPGVTAKDIILAVIAQIGTGGGQGHVIEYRGEAIRSLSMEARMTICNMSIEAGARAGM 232 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEP------ 311 + D+TTF YL+G+ +VEY + + +D A F + + +L P Sbjct: 233 IAPDQTTFDYLKGRPHAPKGELWDQAVEYWKTLPTDEGAVFDKEVFLNADELSPFVTWGT 292 Query: 312 ----------VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKT 416 VV P S P RA A + +D+KID V++GSCT G+ Sbjct: 293 NPGQGVPLDSVVPDPESFTDPVERAAAEKALAYMDLKPGTRMRDIKIDTVFLGSCTNGRI 352 Query: 417 EDFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 ED AAA+V G+KV V +VP +Q+V Sbjct: 353 EDLRAAAEVL--KGRKVADGVRMLVVPGSQRV 382
>LEU2_ERWCT (Q6D0G6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 103 bits (256), Expect = 5e-22 Identities = 78/218 (35%), Positives = 105/218 (48%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ +G T +EF G I +L+ME RMTLCNM IE G K G+V DE Sbjct: 178 ITAKDIVLAIIGKTGSAGGTGHVVEFCGKAIRALSMEGRMTLCNMAIEMGAKAGLVAPDE 237 Query: 198 TTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVA-------- 320 TTF YL+G+ +V Y + SD A+F + D +++ P V Sbjct: 238 TTFNYLKGRQFAPKDANWDAAVAYWSTLKSDDDAQFDTIVTLDAAQIAPQVTWGTNPGQV 297 Query: 321 --------KPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIA 431 P S P RA A + DVKID+V+IGSCT + ED A Sbjct: 298 IAVNQEIPNPDSFSDPVERASAAKALAYMDLQPGIKLTDVKIDKVFIGSCTNSRIEDLRA 357 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AA++ A G+KV V ++ VPGSG Sbjct: 358 AAEI--AKGRKVAA-------------GVQAIVVPGSG 380
>LEU2_STRAW (Q82JR8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 103 bits (256), Expect = 5e-22 Identities = 70/218 (32%), Positives = 101/218 (46%), Gaps = 44/218 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + AKDLIL II I G +E+ GS IE L+ME RMT+CNM IEAG + G+ Sbjct: 173 ELPDGVTAKDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGM 232 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF YL+G+ ++ + SD A F ++ + L P V Sbjct: 233 IAPDETTFAYLKGRAHAPEGEEWDAAVAYWKTLKSDEDAEFDAEVVIAAAALSPFVTWGT 292 Query: 330 SPDNRA-------------------------------LARECKDVKIDRVYIGSCTGGKT 416 +P A + +D+K+D V++GSCT G+ Sbjct: 293 NPGQGAPLSASVPDPASYEDASERFAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRI 352 Query: 417 EDFIAAAKVFLASGKKVK--VPTFLVPATQKVWMDVYS 524 ED AAA + G+KV V +VP + +V + S Sbjct: 353 EDLRAAAAI--VEGRKVADGVRMLIVPGSARVGLQAVS 388
>LEU2_PSEAE (Q9HZA3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 103 bits (256), Expect = 5e-22 Identities = 76/222 (34%), Positives = 112/222 (50%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG I +G ++EF GS I L++E RMT+CNM IEAG + G+V Sbjct: 180 LPAGVTAKDIVLAVIGRIGTAGGNGHAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGLV 239 Query: 186 PADETTFKYLEGK---TSVE--------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 D+ T Y++G+ S E ++ + SDA ARF + D ++++P V+ S Sbjct: 240 AVDQKTIDYVKGRPFAPSAEQWDQAVACWQGLVSDADARFDTVVELDAAQIKPQVSWGTS 299 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P+ RAL + D+++DRV+IGSCT + E Sbjct: 300 PEMVLAVDQNVPDPARESDPIKRGSIERALKYMGLRPNQAITDIQLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA+V A G+K V AT K +L VPGSG Sbjct: 360 DLRAAAEV--ARGRK-------VAATIK-----QALVVPGSG 387
>LEU2_BURPS (Q63JK9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 103 bits (256), Expect = 5e-22 Identities = 75/223 (33%), Positives = 108/223 (48%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P AKD++L IIG I +G T ++EF GSTI +LTME RMT+CNM IEAG + G+ Sbjct: 173 QLPRGCTAKDIVLAIIGRIGTAGGTGYAIEFGGSTIRALTMEGRMTVCNMAIEAGARAGM 232 Query: 183 VPADETTFKYLEGK----------TSVEYEPVY-SDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+TT +YL+G+ +VEY + SD A+F D +++ P V Sbjct: 233 VAVDDTTVEYLKGRPFVPTGAEWDQAVEYWKTFRSDEGAQFDRVVELDAAQIVPQVTWGT 292 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RALA + +K+D+++IGSCT + Sbjct: 293 SPEMVTSIDGRVPDPEREKDPVKRDAMERALAYMALAPNTPIEAIKVDKIFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA V ++V L ++ VPGSG Sbjct: 353 EDIRAAAYVVKKLNRRVAPNVRL------------AMVVPGSG 383
>LEU2_BUCAI (P56934) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 102 bits (255), Expect = 6e-22 Identities = 71/223 (31%), Positives = 107/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ ++ AKDLIL IIG++ SG +EF G+ IE ++MEERMT+CNM IE G K+G+ Sbjct: 173 EIQKFVTAKDLILFIIGKLGSSGGAGYIIEFCGNVIEKMSMEERMTICNMAIEIGAKSGL 232 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE TF YL+ K ++ + SD A F ++S L P + Sbjct: 233 IAPDEVTFSYLKNKMYAPRGVFWKKALNFWKNLKSDKNAFFDKVVNINISDLSPQITWGT 292 Query: 330 SPD-------------------NRALARE-CK-----------DVKIDRVYIGSCTGGKT 416 +PD + LA+ CK ++ +D+V+IGSCT G+ Sbjct: 293 NPDQVISIDQKIPDFSSFDNLIKKDLAKSACKYMGLKIGTYLTNITVDKVFIGSCTNGRI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AA+K+ +K+ +V ++ VPGSG Sbjct: 353 EDLRAASKIL---------------KDKKIANNVKAIVVPGSG 380
>LEU2_PELUB (Q4FP15) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 102 bits (254), Expect = 8e-22 Identities = 66/207 (31%), Positives = 103/207 (49%), Gaps = 42/207 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + +KD+ILQIIG+I +G T +E+ GS I SL++E+RMT+CNM IE G + G+ Sbjct: 173 KLPIGVTSKDVILQIIGQIGTAGGTGSVIEYAGSLISSLSVEQRMTICNMTIEGGARAGL 232 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE F+YL+GK +++Y E + +D A+F + + P++ Sbjct: 233 IAPDEKIFEYLKGKPMSPKNENWDKAMKYWESLKTDDGAKFDKEINLVAEDILPMITWGT 292 Query: 330 SPDN--------------------RALARE-----------CKDVKIDRVYIGSCTGGKT 416 SP + +L R D+KID+V+IGSCT G+ Sbjct: 293 SPQDVITIDGKVPNPKNEQDEDKKNSLERSLNYMGLKADTLATDIKIDKVFIGSCTNGRI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPAT 497 ED AAK+ K V +VP + Sbjct: 353 EDLREAAKILKDKKKASHVQAMVVPGS 379
>LEU2_SYNP6 (Q5MZY3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 102 bits (254), Expect = 8e-22 Identities = 69/211 (32%), Positives = 105/211 (49%), Gaps = 43/211 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + AKD+IL II ++ V G + EF GST +++MEERMT+CNM IE G + G Sbjct: 174 ELQPGVYAKDVILHIIRKLGVKGGVGYAYEFAGSTFAAMSMEERMTVCNMAIEGGARCGY 233 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+ T+ YL+G+ +E + S+A A + FD +++ P V Sbjct: 234 VNPDQITYDYLQGREFAPQGEAWDRAIAWWESLRSEADAEYDDVVVFDAAEIAPTVTWGI 293 Query: 330 SP------------------DNRALAREC------------KDVKIDRVYIGSCTGGKTE 419 +P ++RA+A E + K+D +IGSCT G+ Sbjct: 294 TPGQGIGITETIPTPDSLLDEDRAVAAEAYSYMDLEPGAPLQGTKVDVCFIGSCTNGRLS 353 Query: 420 DFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 D AAKV A G+KV + F+VP +++V Sbjct: 354 DLREAAKV--AQGRKVAAGIKAFVVPGSERV 382
>LEU2_RHIPU (P55251) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 755 Score = 102 bits (254), Expect = 8e-22 Identities = 73/223 (32%), Positives = 110/223 (49%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + +KD++L IIG I +G T +EF GS E ++ME RM++CNM IEAG + G+ Sbjct: 179 KLAPGVTSKDIVLHIIGVIGTAGGTGCVIEFCGSAFEQMSMEARMSVCNMSIEAGARAGM 238 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+Y+ G+ +VEY + SD A++ D D + + P + Sbjct: 239 IAPDETTFEYIRGRPLAPTGAEWDKAVEYWRSLRSDPDAKYDVDVFIDAADIAPTLTWGT 298 Query: 330 SPDN--------------------RALAR-----------ECKDVKIDRVYIGSCTGGKT 416 SP + +A+ R ++VKID+V+IGSCT + Sbjct: 299 SPQDVVAITGTTPDPSTVSDPIRRQAMERALDYIGLKPNTPMQEVKIDKVFIGSCTNSRI 358 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA + A G+ V W VY++ VPGSG Sbjct: 359 EDLRAAAAI--AKGRHV-----------ADW--VYAMVVPGSG 386
>LEU2_BUCUO (Q9EVI0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 102 bits (254), Expect = 8e-22 Identities = 69/223 (30%), Positives = 109/223 (48%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P ++ AKD+IL IIG++ S T +EF G+ ++ ++MEERMT+CNM IE G K+G+ Sbjct: 173 EIPKFVTAKDIILFIIGKLGSSSGTGYVIEFCGNVVKKMSMEERMTVCNMAIEMGAKSGL 232 Query: 183 VPADETTFKYLEG----------KTSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T++YL+ K S++Y + SD+ A+F + D+S L P + Sbjct: 233 IAPDEITYEYLKNKMYSPYGIFWKNSLDYWRFLKSDSDAQFDKYFTIDISNLAPQITWGT 292 Query: 330 SPD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKT 416 +PD A CK ++ IDRV+IGSCT + Sbjct: 293 NPDQVISINEKIPDYNKIDSLVKKDAAKSACKYMGLRSDTYLTNISIDRVFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +A+ ++ +K+ V ++ VPGSG Sbjct: 353 EDLRSAS---------------VILKNKKIANHVKAIVVPGSG 380
>LEU2_VIBCH (Q9KP81) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 102 bits (253), Expect = 1e-21 Identities = 69/212 (32%), Positives = 108/212 (50%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + AKD++L IIG+ + +G T +EF G I L+ME RMT+CNM IE G K G+ Sbjct: 175 KVAPGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAIRDLSMEGRMTVCNMAIELGAKAGL 234 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D TTF Y++G+ +V+Y + + +D A+F + + S+++P V Sbjct: 235 IAPDATTFNYIKGRKFAPQGSDWDAAVDYWQTLKTDEDAQFDAVVTLEASEIKPQVTWGT 294 Query: 330 SPDN------------------------RALA-------RECKDVKIDRVYIGSCTGGKT 416 +P +ALA + D K+D+V++GSCT + Sbjct: 295 NPGQVIAVDEPIPSPSQFADPVERSSAEKALAYMGLEAGKMLSDYKVDKVFVGSCTNSRI 354 Query: 417 EDFIAAAKVFLASGKKV--KVPTFLVPATQKV 506 ED AAA V A GKKV V +VP +++V Sbjct: 355 EDMRAAAAV--AKGKKVASHVQALIVPGSEQV 384
>LEU2_PSE14 (Q48K99) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 102 bits (253), Expect = 1e-21 Identities = 76/223 (34%), Positives = 115/223 (51%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD++L +IG+I +G ++EF GS I L++E RMT+CNM IEAG + G+ Sbjct: 178 QLPFGVTAKDIVLAVIGKIGTAGGNGYAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGM 237 Query: 183 VPADETTFKYLEGK----------TSVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V DE T +Y++G+ +VE ++ + SDA A F + R D ++++P V+ Sbjct: 238 VATDEKTVEYVKGRPFAPKGAEWDLAVEAWKDLVSDADAVFDTVVRLDAAQIKPQVSWGT 297 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL + D+++DRV+IGSCT + Sbjct: 298 SPEMVLAVDQNVPDPAQEPDLVKRGSIERALKYMGLKANQPITDIQLDRVFIGSCTNSRI 357 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA V A G+K V AT K ++ VPGSG Sbjct: 358 EDLRAAADV--AKGRK-------VAATIK-----QAIVVPGSG 386
>LEU2_BUCUA (Q9EVG5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 102 bits (253), Expect = 1e-21 Identities = 69/223 (30%), Positives = 108/223 (48%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 EMP ++ AKD+IL IIG++ S +EF G+ I++++MEERMT+CNM +E G K+G+ Sbjct: 173 EMPKFVTAKDIILFIIGKLGSSSGAGHVIEFCGNVIKNMSMEERMTICNMAVEMGAKSGL 232 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T+KYL+ K S++Y + + SD A F D+S L P + Sbjct: 233 IAPDEITYKYLKDKIYSPFGIFWEKSLDYWKFLKSDKNAYFDKCVTVDISNLAPQITWGT 292 Query: 330 SPD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKT 416 +PD ++ C+ ++ ID+V+IGSCT + Sbjct: 293 NPDQVISIDEKIPDYNNINSIVKRKSAKSACEYMGLQSNTYLTNISIDKVFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +A+K+ +KV V ++ VPGSG Sbjct: 353 EDLRSASKIL---------------KNKKVAKHVTAIVVPGSG 380
>LEU2_PSESM (Q884C2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 475 Score = 101 bits (252), Expect = 1e-21 Identities = 75/223 (33%), Positives = 115/223 (51%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD++L +IG+I +G ++EF GS I L++E RMT+CNM IEAG + G+ Sbjct: 178 QLPFGVTAKDIVLAVIGKIGTAGGNGYAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGM 237 Query: 183 VPADETTFKYLEGK----------TSVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V DE T +Y++G+ +VE ++ + SDA A F + + D ++++P V+ Sbjct: 238 VATDEKTIEYVKGRPFAPKGAEWDLAVEAWQDLVSDADAVFDTVVKLDAAQIKPQVSWGT 297 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL + D+++DRV+IGSCT + Sbjct: 298 SPEMVLAVDQNVPDPAQEPDLVKRGSIERALKYMGLKANQPITDIQLDRVFIGSCTNSRI 357 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA V A G+K V AT K ++ VPGSG Sbjct: 358 EDLRAAADV--AKGRK-------VAATIK-----QAIVVPGSG 386
>LEU2_CORJK (Q4JUX2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 101 bits (252), Expect = 1e-21 Identities = 72/212 (33%), Positives = 101/212 (47%), Gaps = 42/212 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + +KDLIL II +I G +E+ G IE L+ME RMT+CNM IEAG + G+ Sbjct: 181 ELQPDVTSKDLILAIIAKIGTGGGQGHIIEYRGEAIEKLSMEARMTMCNMSIEAGARAGM 240 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D+ TF YLEG+ +VEY + + +D A+F + D S L P V Sbjct: 241 IAPDQVTFDYLEGRPHAPKGADWDAAVEYWKSLRTDDDAQFDTVVHIDGSALTPFVTWGT 300 Query: 330 SP------------------DNRALARE-------------CKDVKIDRVYIGSCTGGKT 416 +P DN LA E +D+KID V++GSCT + Sbjct: 301 NPGQGLPLAEAIPQLEDFTNDNDRLAAERAMEYMDLQPGTPLRDIKIDTVFLGSCTNSRI 360 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWM 512 ED AAA V +VP++ +V M Sbjct: 361 EDLRAAADVLKGRTVADGTRMIVVPSSTRVKM 392
>LEU2_PASMU (Q9CJN7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 101 bits (251), Expect = 2e-21 Identities = 75/216 (34%), Positives = 103/216 (47%), Gaps = 42/216 (19%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD++L IIG+ ++ G T +EF G I L+ME RMT+CNM IE G K+G++ DETT Sbjct: 179 AKDIVLAIIGKTTMGGGTGHVVEFCGEAIRDLSMEGRMTVCNMAIELGAKSGIIAPDETT 238 Query: 204 FKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVV----------- 317 F YL+ K +V Y + ++SD A F + + S++EP V Sbjct: 239 FAYLKDKPYAPKGKDWDEAVAYWQTLHSDEGAEFDTVVTLEASEIEPQVTWGTNPGQVIG 298 Query: 318 --------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIAAA 437 A+ P R A + DV ID+V+IGSCT + ED AAA Sbjct: 299 INQPIPNPAEMSDPIERQSAEKALAYMDLPHSIKLTDVAIDKVFIGSCTNSRIEDLRAAA 358 Query: 438 KVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 + A G+KV V +L VPGSG Sbjct: 359 AI--AKGRKVA-------------DGVQALVVPGSG 379
>LEU2_AZOVI (P96195) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 101 bits (251), Expect = 2e-21 Identities = 64/189 (33%), Positives = 92/189 (48%), Gaps = 42/189 (22%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + AKD++L +IG I +G T ++EF GS I L+ME RMTLCNM IEAG + G+ Sbjct: 175 ELPLGVSAKDIVLAVIGRIGTAGGTGHALEFAGSAIRGLSMEGRMTLCNMAIEAGARVGM 234 Query: 183 VPADETTFKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V DE T Y++G K ++ + SDA A F + ++ P V Sbjct: 235 VAVDEKTIDYVKGRPYAPQGADWDKAVAQWRELVSDADAGFDTVVELKAEEIRPQVTWGT 294 Query: 330 SPD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKT 416 SP+ ++ R K ++K+DRV+IGSCT + Sbjct: 295 SPEMVLPVDERVPDPASESDPVKRDSIVRALKYMGLAANQPIGEIKVDRVFIGSCTNSRI 354 Query: 417 EDFIAAAKV 443 ED AAA+V Sbjct: 355 EDLRAAAEV 363
>LEU2_RALSO (Q8XXX3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 100 bits (250), Expect = 2e-21 Identities = 73/222 (32%), Positives = 107/222 (48%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P AKD++L IIG+I +G T +MEF GS I +L+ME RMT+CNM IEAG + G+V Sbjct: 174 LPRGCTAKDIVLAIIGKIGTAGGTGYAMEFGGSAIRALSMEGRMTVCNMAIEAGARAGMV 233 Query: 186 PADETTFKYLEGK----TSVEYE-------PVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 D+ T +Y++G+ VE+E ++SD ARF ++ P V+ S Sbjct: 234 GVDDITLEYIKGRPFAPQGVEWEQAVAYWRSLHSDEGARFDHVVELRAEEIRPQVSWGTS 293 Query: 333 PD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKTE 419 P+ A+ R + D++ID+V+IGSCT + E Sbjct: 294 PEMVVSIEDRVPDPDKEKDPVKRNAMERALEYMALQPNVAIGDIRIDKVFIGSCTNSRIE 353 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA V GK++ L ++ VPGSG Sbjct: 354 DMRAAAWVVQKLGKRIASNVKL------------AMVVPGSG 383
>LEU2_PROMT (Q46HB8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 100 bits (250), Expect = 2e-21 Identities = 68/209 (32%), Positives = 97/209 (46%), Gaps = 41/209 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ + AKDLIL II + V G + EF G IE L+ME RMT+CNM IE G + G Sbjct: 174 ELQKGVYAKDLILHIIRHLGVKGGVGFAYEFAGPAIEKLSMEGRMTICNMAIEGGARCGY 233 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTFKY++GK ++ + SD++A F + + D S +EP V Sbjct: 234 INPDETTFKYIKGKEHAPKGQEWDKAISWWKSLASDSKATFDDEIQLDGSSIEPTVTWGI 293 Query: 330 SPDNRALARE-------------------CKDV-----------KIDRVYIGSCTGGKTE 419 +P +E CK + ID +IGSCT G+ Sbjct: 294 TPGQGISIKETIPNPEFLPKNEQQIAKDACKYMNLKPDEPIEGQSIDVCFIGSCTNGRLS 353 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKV 506 D A+K+ + + F+VP +QKV Sbjct: 354 DLEEASKIVKGNTVADGIRAFVVPGSQKV 382
>LEU2_METCA (Q606F2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 100 bits (249), Expect = 3e-21 Identities = 72/223 (32%), Positives = 103/223 (46%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + AKDL+L +IG I +G T ++EF G I L+ME RMT+CNM IEAG + G+ Sbjct: 174 KLAPGVTAKDLVLAVIGRIGTAGGTGYTIEFAGEAIRGLSMEGRMTVCNMAIEAGARAGL 233 Query: 183 VPADETTFKYLEGKT----------SVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V DE T YLEG+ +VE ++ ++SD A F D + ++P V Sbjct: 234 VAVDEVTLDYLEGRPFAPAGALWERAVEAWKDLHSDPDAVFDKVVEIDAASIKPQVTWGT 293 Query: 330 SPDNRA---------------LARECKD----------------VKIDRVYIGSCTGGKT 416 SP+ + RE + +++DRV+IGSCT + Sbjct: 294 SPEQVVPVDAEVPDPATEADPVRRESMERALQYMDLLPGTPIGAIRVDRVFIGSCTNARI 353 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA+V + V LV VPGSG Sbjct: 354 EDLRAAAEVVRGHKRAASVKQALV--------------VPGSG 382
>LEU2_CAUCR (Q9ABN0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 100 bits (249), Expect = 3e-21 Identities = 67/189 (35%), Positives = 89/189 (47%), Gaps = 42/189 (22%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++PP + KD+ L +IGEI +G T +EF G I L+ME RMTLCN+ IE G K G+ Sbjct: 176 QLPPGVTGKDVALAVIGEIGTAGGTGYVIEFAGEAIAGLSMEGRMTLCNLTIEGGAKAGL 235 Query: 183 VPADETTFKYLEGKTSV-----------EYEPVYSDAQARFYSDYRFDVSKLEPVVA--- 320 V D+ TF Y++GK + ++ ++D A F D S L P+V Sbjct: 236 VAPDDKTFAYIQGKPAAPKGAAWDMALSHWKTFFTDEDAVFDRTVVIDGSALVPMVTWGT 295 Query: 321 -------------KPHS---PDNRALARECKD------------VKIDRVYIGSCTGGKT 416 P S PD RA A D +IDRV+IGSCT + Sbjct: 296 SPEDVIPVTGNVPDPESFATPDKRAAAHRALDYMGLKAGQPISEARIDRVFIGSCTNSRI 355 Query: 417 EDFIAAAKV 443 ED AAA V Sbjct: 356 EDMRAAAAV 364
>LEU2_NEIG1 (Q5F8T1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 100 bits (249), Expect = 3e-21 Identities = 74/216 (34%), Positives = 99/216 (45%), Gaps = 42/216 (19%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+ L IIG+I +G T ++EF G I SL+ME RMTLCNM IEAG ++G+V D+TT Sbjct: 182 AKDVALYIIGQIGTAGGTGYAVEFGGEAIRSLSMEGRMTLCNMAIEAGARSGMVAVDQTT 241 Query: 204 FKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 Y++GK +VEY + SD A F +YRF+ +EP V SP+ Sbjct: 242 IDYVKGKPFAPEGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVLN 301 Query: 339 --------------------NRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAA 437 RAL ++ +D V+IGSCT + ED AA Sbjct: 302 IGGKVPNPAEETDPVKRSGIERALEYMGLKAGTPLNEIPVDIVFIGSCTNSRIEDLREAA 361 Query: 438 KVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 + K V L+ VPGSG Sbjct: 362 AIAKGHKKAGNVQRVLI--------------VPGSG 383
>LEU2_PSEF5 (Q4KF08) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 100 bits (249), Expect = 3e-21 Identities = 66/196 (33%), Positives = 104/196 (53%), Gaps = 42/196 (21%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GS I L++E RMT+CNM IEAG + G+V Sbjct: 179 LPFGVTAKDIVLAVIGKIGTAGGNGHAIEFAGSAIRELSVEGRMTICNMSIEAGARVGLV 238 Query: 186 PADETTFKYLEGK----------TSVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 ADE T Y++G+ +VE ++ + SDA A+F + D ++++P V+ S Sbjct: 239 AADEKTVAYVKGRPFAPKDAEWDLAVEAWKDLVSDADAKFDTVVELDAAQIKPQVSWGTS 298 Query: 333 PD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKTE 419 P+ ++ R K D+++DRV+IGSCT + E Sbjct: 299 PEMVLAVDQNVPDPAKEMDLVKRDSIVRALKYMGLSANQAITDIQLDRVFIGSCTNSRIE 358 Query: 420 DFIAAAKVFLASGKKV 467 D AAA +A G+KV Sbjct: 359 DLRAAA--VIAKGRKV 372
>LEU2_BACCR (Q81G10) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 100 bits (248), Expect = 4e-21 Identities = 69/203 (33%), Positives = 99/203 (48%), Gaps = 35/203 (17%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL ++ + V+ T MEF G I ++ MEERMTLCNM IE G K G+ Sbjct: 172 KLPQGVYAKDIILHLLSKYGVAVGTGYVMEFYGEAIHAMDMEERMTLCNMAIEGGAKAGI 231 Query: 183 VPADETTFKYLEGK--TSVEYEPV-------YSDAQARFYSDYRFDVSKLEPVVA----- 320 + DE TF Y++G+ +YE + Y+D A + DV+ L P V Sbjct: 232 IAPDEKTFAYVKGRKYAPKDYESIKKKWSELYTDLDAVYDLHILVDVTDLAPYVTWGTNP 291 Query: 321 ------------KPHSPDNRALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAAKV 443 K + D RA + + D+ + V+IGSCT + D AA V Sbjct: 292 SMGVRIDEKLPEKHDANDERAFSYMGLSPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASV 351 Query: 444 FLASGKKVK--VPTFLVPATQKV 506 GKKVK V +VP +Q+V Sbjct: 352 --VKGKKVKEGVRALVVPGSQRV 372
>LEU2_VIBPA (Q87SS9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 100 bits (248), Expect = 4e-21 Identities = 68/212 (32%), Positives = 109/212 (51%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + AKD++L IIG+ + +G T +EF G I L+ME RMT+CNM IE G K G+ Sbjct: 173 KVAPGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLSMEGRMTVCNMAIELGAKAGL 232 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+Y++G+ +VEY + + +DA A F + + + ++P V Sbjct: 233 IAPDETTFEYIKGRKFSPQGADFDAAVEYWKTLKTDADAEFDAVVTLNAADIKPQVTWGT 292 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 +P +ALA + D ++++V++GSCT + Sbjct: 293 NPGQVIAVDQPIPAPESFTDPIEKASAEKALAYMGLEAGKSLSDYQVNKVFVGSCTNSRI 352 Query: 417 EDFIAAAKVFLASGKKV--KVPTFLVPATQKV 506 ED AAA V A G+KV V +VP +++V Sbjct: 353 EDMRAAAVV--AKGRKVASHVQALIVPGSEQV 382
>LEU2_BORPE (Q7VY75) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 99.8 bits (247), Expect = 5e-21 Identities = 69/197 (35%), Positives = 95/197 (48%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P AKD++L IIG I +G T ++EF GSTI L++E RMT+CNM IEAG ++G+ Sbjct: 173 ELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVEGRMTVCNMAIEAGARSGM 232 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+ T Y G+ + ++SDA ARF D ++P V Sbjct: 233 VAVDDKTIDYFRGRPFAPVGVLWDQAVGYWRTLHSDAGARFDRVINVDARDIKPQVTWGT 292 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL D+++DRV+IGSCT + Sbjct: 293 SPEMVLPVDGRVPDPDREKDDVRRSGMERALEYMGLKPNTPLVDIRVDRVFIGSCTNSRI 352 Query: 417 EDFIAAAKVFLASGKKV 467 ED AAA V A GK+V Sbjct: 353 EDLRAAAVV--ARGKRV 367
>LEU2_BORPA (Q7W931) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 99.8 bits (247), Expect = 5e-21 Identities = 69/197 (35%), Positives = 95/197 (48%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P AKD++L IIG I +G T ++EF GSTI L++E RMT+CNM IEAG ++G+ Sbjct: 173 ELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVEGRMTVCNMAIEAGARSGM 232 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+ T Y G+ + ++SDA ARF D ++P V Sbjct: 233 VAVDDKTIDYFRGRPFAPVGVLWDQAVGYWRTLHSDAGARFDRVINVDARDIKPQVTWGT 292 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL D+++DRV+IGSCT + Sbjct: 293 SPEMVLPVDGRVPDPDREKDDVRRSGMERALEYMGLKPNTPLVDIRVDRVFIGSCTNSRI 352 Query: 417 EDFIAAAKVFLASGKKV 467 ED AAA V A GK+V Sbjct: 353 EDLRAAAVV--ARGKRV 367
>LEU2_BORBR (Q7WKH6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 99.8 bits (247), Expect = 5e-21 Identities = 69/197 (35%), Positives = 95/197 (48%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P AKD++L IIG I +G T ++EF GSTI L++E RMT+CNM IEAG ++G+ Sbjct: 173 ELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVEGRMTVCNMAIEAGARSGM 232 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+ T Y G+ + ++SDA ARF D ++P V Sbjct: 233 VAVDDKTIDYFRGRPFAPVGVLWDQAVGYWRTLHSDAGARFDRVINVDARDIKPQVTWGT 292 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL D+++DRV+IGSCT + Sbjct: 293 SPEMVLPVDGRVPDPDREKDDVRRSGMERALEYMGLKPNTPLVDIRVDRVFIGSCTNSRI 352 Query: 417 EDFIAAAKVFLASGKKV 467 ED AAA V A GK+V Sbjct: 353 EDLRAAAVV--ARGKRV 367
>LEU2_PSEHT (Q3IJS4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 99.8 bits (247), Expect = 5e-21 Identities = 71/220 (32%), Positives = 102/220 (46%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKDLI+ +IG++ +G T EF G IE+L+ME RMTLCNM IE G K G++ + Sbjct: 176 PTVTAKDLIMAVIGKLGTAGGTGYVAEFCGEGIEALSMEARMTLCNMSIEMGAKAGLIAS 235 Query: 192 DETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD 338 D+ T+ YL+G+ +V+Y E + +D A+F + S ++P + SP+ Sbjct: 236 DQITYDYLKGRPFAPKGADFDAAVKYWETLKTDDGAQFDHVVELEASSIQPQITWGTSPE 295 Query: 339 NRALAREC-------------------------------KDVKIDRVYIGSCTGGKTEDF 425 EC K+D V+IGSCT + ED Sbjct: 296 QVIGVDECIPDPDKEPDLIKADAIRSALKYMGLKAGEKLSSAKVDTVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAAK+ GKKV + +L VPGSG Sbjct: 356 RAAAKI--VEGKKVVA-------------GIEALIVPGSG 380
>LEU2_SALPA (Q5PDG3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 99.4 bits (246), Expect = 7e-21 Identities = 78/220 (35%), Positives = 106/220 (48%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I +L+ME RMTLCNM IE G K G+V Sbjct: 176 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLCNMAIEMGAKAGLVAP 235 Query: 192 DETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEP--------- 311 DETTF Y++G+ +VEY + + +D A F + ++ P Sbjct: 236 DETTFNYVKGRLHAPKGCDFDEAVEYWKTLKTDDGATFDTVVTLRAEEIAPQVTWGTNPG 295 Query: 312 -------VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 ++ P S P RA A + DV ID+V+IGSCT + ED Sbjct: 296 QVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPLTDVAIDKVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA+V A G+KV P Q +L VPGSG Sbjct: 356 RAAAEV--AKGRKV------APGVQ-------ALVVPGSG 380
>LEU21_SALCH (Q57TE8) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 466 Score = 99.4 bits (246), Expect = 7e-21 Identities = 78/220 (35%), Positives = 106/220 (48%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I +L+ME RMTLCNM IE G K G+V Sbjct: 176 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLCNMAIEMGAKAGLVAP 235 Query: 192 DETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEP--------- 311 DETTF Y++G+ +VEY + + +D A F + ++ P Sbjct: 236 DETTFNYVKGRLHAPKGRDFDEAVEYWKTLKTDDGATFDTVVTLRAEEIAPQVTWGTNPG 295 Query: 312 -------VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 ++ P S P RA A + DV ID+V+IGSCT + ED Sbjct: 296 QVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPLTDVAIDKVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA+V A G+KV P Q +L VPGSG Sbjct: 356 RAAAEV--AKGRKV------APGVQ-------ALVVPGSG 380
>LEU2_SALTI (Q8Z9I2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 99.4 bits (246), Expect = 7e-21 Identities = 78/220 (35%), Positives = 106/220 (48%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I +L+ME RMTLCNM IE G K G+V Sbjct: 175 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLCNMAIEMGAKAGLVAP 234 Query: 192 DETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEP--------- 311 DETTF Y++G+ +VEY + + +D A F + ++ P Sbjct: 235 DETTFNYVKGRLHAPKGRDFDEAVEYWKTLKTDDGATFDTVVTLRAEEIAPQVTWGTNPG 294 Query: 312 -------VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 ++ P S P RA A + DV ID+V+IGSCT + ED Sbjct: 295 QVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPLTDVAIDKVFIGSCTNSRIEDL 354 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA+V A G+KV P Q +L VPGSG Sbjct: 355 RAAAEV--AKGRKV------APGVQ-------ALVVPGSG 379
>LEU21_SALTY (P15717) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 465 Score = 99.4 bits (246), Expect = 7e-21 Identities = 78/220 (35%), Positives = 106/220 (48%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I +L+ME RMTLCNM IE G K G+V Sbjct: 175 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLCNMAIEMGAKAGLVAP 234 Query: 192 DETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEP--------- 311 DETTF Y++G+ +VEY + + +D A F + ++ P Sbjct: 235 DETTFNYVKGRLHAPKGRDFDEAVEYWKTLKTDDGATFDTVVALRAEEIAPQVTWGTNPG 294 Query: 312 -------VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 ++ P S P RA A + DV ID+V+IGSCT + ED Sbjct: 295 QVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPLTDVAIDKVFIGSCTNSRIEDL 354 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA+V A G+KV P Q +L VPGSG Sbjct: 355 RAAAEV--AKGRKV------APGVQ-------ALVVPGSG 379
>LEU2_VIBF1 (Q5E858) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 99.4 bits (246), Expect = 7e-21 Identities = 67/207 (32%), Positives = 102/207 (49%), Gaps = 44/207 (21%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ + +G T +EF G I LTME RMT+CNM IE G K G++ D+ Sbjct: 180 ITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVCNMAIELGAKAGLIAPDQ 239 Query: 198 TTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDN- 341 TTF Y+ G+ ++EY + +D A F + D S+++P V +P Sbjct: 240 TTFDYIAGRKFSPQDADLDAAIEYWSSLKTDDDAEFDAVVTLDASEIKPQVTWGTNPGQV 299 Query: 342 -----------------------RALA-------RECKDVKIDRVYIGSCTGGKTEDFIA 431 +ALA + D +D+V++GSCT + ED A Sbjct: 300 IAVDAPIPAPESFADPVEKASAEKALAYMGLEAGKSLSDYNVDKVFVGSCTNSRIEDMRA 359 Query: 432 AAKVFLASGKKV--KVPTFLVPATQKV 506 AA + A G+KV V +VP +++V Sbjct: 360 AAAI--AKGRKVASHVQALIVPGSEQV 384
>LEU22_SALTY (Q8ZRJ0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 473 Score = 99.0 bits (245), Expect = 9e-21 Identities = 69/212 (32%), Positives = 99/212 (46%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P AKD++L+++ I GAT ++EFVG I +L++E RMTLCNM +EAG + + Sbjct: 176 ELPFACSAKDIVLELLERIGADGATGYAIEFVGEAISALSVEGRMTLCNMAVEAGARGAI 235 Query: 183 VPADETTFKYLEGKTS-----------VEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D+ F Y+ GK +E+ + SDA A F + LEP V Sbjct: 236 IAPDKKVFDYIYGKPQMPVGELWQQALLEWSQLSSDADAVFDKTVAINCHDLEPKVTWGI 295 Query: 330 SPDN------------------RALARE-------------CKDVKIDRVYIGSCTGGKT 416 SPD + LA E KD++I +IGSCT G+ Sbjct: 296 SPDQTGSITGRVPFPEQETNPLKRLALEKALHYMGLTAGMLLKDIRISHAFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKV--KVPTFLVPATQKV 506 ED A AKV G+K+ V +VP + V Sbjct: 356 EDLRAVAKVL--EGRKIASHVRGIIVPGSTMV 385
>LEU22_SALCH (Q57SN1) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 473 Score = 99.0 bits (245), Expect = 9e-21 Identities = 69/212 (32%), Positives = 99/212 (46%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P AKD++L+++ I GAT ++EFVG I +L++E RMTLCNM +EAG + + Sbjct: 176 ELPFACSAKDIVLELLERIGADGATGYAIEFVGEAISALSVEGRMTLCNMAVEAGARGAI 235 Query: 183 VPADETTFKYLEGKTS-----------VEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D+ F Y+ GK +E+ + SDA A F + LEP V Sbjct: 236 IAPDKKVFDYIYGKPQMPVGELWQQALLEWSQLSSDADAVFDKTVAINCHDLEPKVTWGI 295 Query: 330 SPDN------------------RALARE-------------CKDVKIDRVYIGSCTGGKT 416 SPD + LA E KD++I +IGSCT G+ Sbjct: 296 SPDQTGSITGRVPFPEQETNPLKRLALEKALHYMGLTAGMLLKDIRISHAFIGSCTNGRI 355 Query: 417 EDFIAAAKVFLASGKKV--KVPTFLVPATQKV 506 ED A AKV G+K+ V +VP + V Sbjct: 356 EDLRAVAKVL--EGRKIASHVRGIIVPGSTMV 385
>LEU2_STRCO (O86534) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 99.0 bits (245), Expect = 9e-21 Identities = 66/216 (30%), Positives = 101/216 (46%), Gaps = 42/216 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + AKDLIL II I G +E+ G IE L+ME RMT+CNM IEAG + G+ Sbjct: 173 ELPEGVTAKDLILAIIARIGTGGGQGYILEYRGEAIEKLSMEARMTICNMSIEAGARAGM 232 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF YL+G+ +VEY + + +D A F ++ + ++L P V Sbjct: 233 IAPDETTFAYLQGRPHAPEGADWDAAVEYWKTLRTDDDAEFDAEVVIEAAELAPFVTWGT 292 Query: 330 SPDNRA-------------------------------LARECKDVKIDRVYIGSCTGGKT 416 +P A + + +++D V++GSCT G+ Sbjct: 293 NPGQGAPLSAAVPDPASYEDASERFAAEKALEYMGLEAGQPLRSIQVDTVFVGSCTNGRI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYS 524 ED AAA++ V +VP + +V + S Sbjct: 353 EDLRAAAEIVRDRKVADGVRMLVVPGSARVGLQAVS 388
>LEU2_BUCML (Q9EVG2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 442 Score = 99.0 bits (245), Expect = 9e-21 Identities = 70/223 (31%), Positives = 107/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P ++ AKD+IL IIG+ S + +EF G+ IE+++MEERMT+CNM IE G K+G+ Sbjct: 173 QIPKFISAKDIILFIIGKXGSSIGSGYVVEFCGNVIETMSMEERMTICNMAIEMGAKSGL 232 Query: 183 VPADETTFKYLEGKTSVEY-----------EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D+TT+ YL+ K Y + + SD A F + D+S L P + Sbjct: 233 IAPDKTTYAYLKNKIYSPYGVFWEKSLDFWQTLKSDKDAFFDKIFTIDISNLAPQITWGT 292 Query: 330 SPD-------------------NRALARE-CK-----------DVKIDRVYIGSCTGGKT 416 +PD R LA+ CK ++ ID+V+IGS T + Sbjct: 293 NPDQVISIDEKIPNYETFSSLTQRNLAKSACKYMGLKKESYLTNISIDKVFIGSXTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAK+ +K+ +V ++ VPGSG Sbjct: 353 EDLRLAAKIL---------------KNKKISNNVQAIVVPGSG 380
>LEU2_PSEU2 (Q4ZUZ6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 99.0 bits (245), Expect = 9e-21 Identities = 67/197 (34%), Positives = 104/197 (52%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD++L +IG+I +G ++EF GS I L++E RMT+CNM IEAG + G+ Sbjct: 178 QLPFGVTAKDIVLAVIGKIGTAGGNGYAIEFAGSAIRDLSIEGRMTICNMSIEAGARVGM 237 Query: 183 VPADETTFKYLEGK----------TSVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V DE T +Y++G+ +VE ++ + SD A F + R D ++++P V+ Sbjct: 238 VATDEKTVEYVKGRPFAPKGAEWDLAVEAWKDLVSDPDAVFDTVVRLDAAQIKPQVSWGT 297 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL + D+++DRV+IGSCT + Sbjct: 298 SPEMVLAVDQNVPDPAQEPDLVKRGSIERALKYMGLKANQPITDIQLDRVFIGSCTNSRI 357 Query: 417 EDFIAAAKVFLASGKKV 467 ED AAA V A G+KV Sbjct: 358 EDLRAAADV--AKGRKV 372
>LEU2_PYRAE (Q8ZW41) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 415 Score = 99.0 bits (245), Expect = 9e-21 Identities = 55/169 (32%), Positives = 92/169 (54%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E P ++ KD+ L ++G+ G S+E T ++ M++R T+ NM E G + Sbjct: 164 EFPIGVMGKDVALHLLGQFGAEGFNGYSVEVFVETPKAFPMDDRATVANMSTEMGADALM 223 Query: 183 VPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAREC 362 D T +YL+ + V+Y P + + Y ++ +LEP+VA P+S DN RE Sbjct: 224 FIPDVITAEYLKTERGVDYTPPRIEP-GNYADKYTVELPRLEPLVAAPYSVDNIKSVREV 282 Query: 363 KDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 + V++D+V+IGSCT G+ D AAK+ G++VK +PA+ +V+ Sbjct: 283 EGVEVDQVFIGSCTNGRLSDIAVAAKIL--KGRRVKSRCIAIPASYEVF 329
>LEU2_PHOLL (Q7N127) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 99.0 bits (245), Expect = 9e-21 Identities = 76/218 (34%), Positives = 105/218 (48%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ +G T +EF G IE+L+ME RMTLCNM IE G K G+V DE Sbjct: 178 ITAKDIVLAIIGKTGSAGGTGYVVEFCGKAIEALSMEGRMTLCNMAIEMGAKAGLVAPDE 237 Query: 198 TTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEP----------- 311 TTF Y++G+ +V Y + + SD A++ + + ++ P Sbjct: 238 TTFTYMKGRQFSPKGELWEQAVAYWKTLKSDPDAQYDTIVTINAEEISPQVTWGTNPGQV 297 Query: 312 -----VVAKPHS---PDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIA 431 + P S P RA A + DVKID+V+IGSCT + ED A Sbjct: 298 IAIDQTIPAPESFSDPVERASAEKALAYMDLKPGIKLTDVKIDKVFIGSCTNSRIEDLRA 357 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AA + A G KV P Q ++ VPGSG Sbjct: 358 AAAI--AQGHKV------APGVQ-------AIVVPGSG 380
>LEU2_NEIMB (Q9JZI5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 99.0 bits (245), Expect = 9e-21 Identities = 73/216 (33%), Positives = 98/216 (45%), Gaps = 42/216 (19%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+ L IIG+I +G T ++EF G I SL+ME RMTLCNM IEAG ++G+V D+TT Sbjct: 182 AKDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMESRMTLCNMAIEAGARSGMVAVDQTT 241 Query: 204 FKYLEGKT----------SVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 Y++ K +VEY + SD A F +YRF+ +EP V SP+ Sbjct: 242 IDYVKDKPFAPEGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVLD 301 Query: 339 --------------------NRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAA 437 RAL ++ +D V+IGSCT + ED AA Sbjct: 302 ISSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRIEDLREAA 361 Query: 438 KVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 + K V L+ VPGSG Sbjct: 362 AIAKDRKKAANVQRVLI--------------VPGSG 383
>LEU2_LEPIN (Q8F4E6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 99.0 bits (245), Expect = 9e-21 Identities = 69/205 (33%), Positives = 102/205 (49%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL IIG+I +GAT +E+ GS I++L+ME RMT+CNM IEAG + G++ DETT Sbjct: 179 AKDIILAIIGKIGTAGATGYVIEYRGSAIQALSMEARMTICNMSIEAGARAGLIAPDETT 238 Query: 204 FKYLEGK----TSVEYE-------PVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 F Y++GK VE++ +D A+F ++ P+V SP Sbjct: 239 FNYIQGKDFSPKGVEWDLAVKKWKHYVTDEGAKFDRTVILHADEIAPMVTWGTSPSQVVS 298 Query: 339 ---------------------------NRALARECKDVKIDRVYIGSCTGGKTEDFIAAA 437 + ++ +D+ I++V+IGSCT + ED AAA Sbjct: 299 IKGVVPDPKDANDPVEKIGIESALKYMDLKSGQKIEDISINKVFIGSCTNSRIEDLRAAA 358 Query: 438 KVFLASGKKV--KVPTFLVPATQKV 506 GKKV KV +VP + +V Sbjct: 359 AT--VKGKKVSSKVQAIVVPGSGRV 381
>LEU2_LEPIC (Q72RC4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 99.0 bits (245), Expect = 9e-21 Identities = 69/205 (33%), Positives = 102/205 (49%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL IIG+I +GAT +E+ GS I++L+ME RMT+CNM IEAG + G++ DETT Sbjct: 179 AKDIILAIIGKIGTAGATGYVIEYRGSAIQALSMEARMTICNMSIEAGARAGLIAPDETT 238 Query: 204 FKYLEGK----TSVEYE-------PVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 F Y++GK VE++ +D A+F ++ P+V SP Sbjct: 239 FNYIQGKDFSPKGVEWDLAVKKWKHYVTDEGAKFDRTVILHADEIAPMVTWGTSPSQVVS 298 Query: 339 ---------------------------NRALARECKDVKIDRVYIGSCTGGKTEDFIAAA 437 + ++ +D+ I++V+IGSCT + ED AAA Sbjct: 299 IKGVVPDPKDANDPVEKIGIESALKYMDLKSGQKIEDISINKVFIGSCTNSRIEDLRAAA 358 Query: 438 KVFLASGKKV--KVPTFLVPATQKV 506 GKKV KV +VP + +V Sbjct: 359 AT--VKGKKVSSKVQAIVVPGSGRV 381
>LEU2_NEIMA (Q9JU82) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 98.6 bits (244), Expect = 1e-20 Identities = 73/216 (33%), Positives = 98/216 (45%), Gaps = 42/216 (19%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+ L IIG+I +G T ++EF G I SL+ME RMTLCNM IEAG ++G+V D+TT Sbjct: 182 AKDVALYIIGQIGTAGGTGYAIEFGGEAIRSLSMEGRMTLCNMAIEAGARSGMVAVDQTT 241 Query: 204 FKYLEGKT----------SVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 Y++ K +VEY + SD A F +YRF+ +EP V SP+ Sbjct: 242 IDYVKDKPFAPEGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVLD 301 Query: 339 --------------------NRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAA 437 RAL ++ +D V+IGSCT + ED AA Sbjct: 302 ISSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRVEDLREAA 361 Query: 438 KVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 + K V L+ VPGSG Sbjct: 362 AIAKDRKKAANVQRVLI--------------VPGSG 383
>LEU22_MANSM (Q65V07) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 469 Score = 98.6 bits (244), Expect = 1e-20 Identities = 73/220 (33%), Positives = 101/220 (45%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +++G T +EF G I L+ME RMT+CNM IE G K G+V Sbjct: 176 PGITAKDIVLAIIGKTTMAGGTGHVVEFCGEAIRDLSMEGRMTVCNMAIEFGAKAGLVAP 235 Query: 192 DETTFKYLEGKTSVEYEPVYSDAQARFYS-----DYRFD--------------------- 293 DETTF+YL+G+ + DA A + + D +FD Sbjct: 236 DETTFEYLKGRPHAPKGKDWDDAVAYWKTLKSDEDAQFDTVVVLEAKDIAPQVTWGTNPG 295 Query: 294 ----VSKLEPVVAKPHSPDNRALAR------------ECKDVKIDRVYIGSCTGGKTEDF 425 + +L P A+ P +A A + K+V +D+V+IGSCT + ED Sbjct: 296 QVIGIDQLVPNPAEMTDPVTKASAEKALAYIGLEPNTDLKNVPVDQVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA V K V LV VPGSG Sbjct: 356 RAAAAVMKGRKKADNVKRVLV--------------VPGSG 381
>LEU2_YEAST (P07264) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 779 Score = 98.6 bits (244), Expect = 1e-20 Identities = 63/189 (33%), Positives = 94/189 (49%), Gaps = 42/189 (22%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + +KDLIL IIG I +G T +EF G IE+L+ME RM++CNM IEAG + G+ Sbjct: 186 KLSPGITSKDLILYIIGLIGTAGGTGCVIEFAGEAIEALSMEARMSMCNMAIEAGARAGM 245 Query: 183 VPADETTFKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+Y +G K ++ + +D A+F + + + P + Sbjct: 246 IKPDETTFQYTKGRPLAPKGAEWEKAVAYWKTLKTDEGAKFDHEINIEAVDVIPTITWGT 305 Query: 330 SPDN------------------------RALA-------RECKDVKIDRVYIGSCTGGKT 416 SP + RALA K +K+D+V+IGSCT G+ Sbjct: 306 SPQDALPITGSVPDPKNVTDPIKKSGMERALAYMGLEPNTPLKSIKVDKVFIGSCTNGRI 365 Query: 417 EDFIAAAKV 443 ED +AA V Sbjct: 366 EDLRSAAAV 374
>LEU2_SHIDS (Q32K22) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 98.2 bits (243), Expect = 1e-20 Identities = 75/220 (34%), Positives = 103/220 (46%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I L+ME RMTLCNM IE G K G+V Sbjct: 176 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAP 235 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP- 335 DETTF Y++G+ ++ + +D A F + ++ P V +P Sbjct: 236 DETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPG 295 Query: 336 ------DN------------RALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 DN RALA + +V ID+V+IGSCT + ED Sbjct: 296 QVISVNDNIPDPASFADPVERALAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA++ A G+KV P Q +L VPGSG Sbjct: 356 RAAAEI--AKGRKV------APGVQ-------ALVVPGSG 380
>LEU2_BLOFL (Q7VQJ8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 98.2 bits (243), Expect = 1e-20 Identities = 62/209 (29%), Positives = 100/209 (47%), Gaps = 42/209 (20%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +PPY+ AKDLIL IIG+I GA+ +EF G I +L+MEERMT+CNM IE G + ++ Sbjct: 174 IPPYITAKDLILFIIGKIGHGGASGYIVEFYGDVINTLSMEERMTICNMSIEMGAASALI 233 Query: 186 PADETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 D TT+ YL+ K + + ++SD F + FD+S ++P + + Sbjct: 234 APDVTTYNYLKNKKFSPNKTHWNQALLFWNTLHSDHDTNFDKIFNFDISNIKPQITWGTN 293 Query: 333 P--------------------DNRALARECK-----------DVKIDRVYIGSCTGGKTE 419 P + +++ + ++ ID+V+IGSCT + E Sbjct: 294 PSQVISIDQPIPKLEIFTDPIERKSVIQALNYMKLTPNTYLTNISIDKVFIGSCTNSRIE 353 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKV 506 D +AA + V +VP ++ V Sbjct: 354 DLRSAANIIKDHKISNNVHAIVVPGSKPV 382
>LEU2_LISMO (Q8Y5R7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 98.2 bits (243), Expect = 1e-20 Identities = 62/202 (30%), Positives = 103/202 (50%), Gaps = 34/202 (16%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL +I V+ T ++E+ G TI +++MEERMT+CNM IE G K G+ Sbjct: 172 KLPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNMAIEGGAKMGM 231 Query: 183 VPADETTFKYLEG---------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP 335 + DETTF+Y+ G K +++ + +D+ A + + D S LEP V +P Sbjct: 232 MAPDETTFEYVRGREYAPTDMDKAISDWKTLQTDSDAEYDLHIKMDASILEPYVTWGTNP 291 Query: 336 D-----NRALARECKDVKIDR--------------------VYIGSCTGGKTEDFIAAAK 440 + ++A E KD+ +R V+IGSCT + D AA+ Sbjct: 292 EMGVPFSKAFP-EIKDMNYERAYEYMGLKPGQTAEQIELGYVFIGSCTNARLSDLEEAAR 350 Query: 441 VFLASGKKVKVPTFLVPATQKV 506 + + K + +VP +++V Sbjct: 351 IVKGNKVKNNIRALVVPGSRQV 372
>LEU2_SULTO (Q974R0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 415 Score = 98.2 bits (243), Expect = 1e-20 Identities = 60/173 (34%), Positives = 90/173 (52%), Gaps = 2/173 (1%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ KD+ L+I+G+ S+E + M+ R T+ NM IE + D Sbjct: 169 WINGKDVALKILGDFKADYFNGMSIEIFVREPSAFPMDFRATVSNMGIEMNADALMFVPD 228 Query: 195 ETTFKYLEGKTSVEYEP--VYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKD 368 E T Y+ KT+ YEP V D A++ +Y D+ KLEP+VA PHS DN E + Sbjct: 229 EETVNYI--KTNRGYEPNIVRPDEGAKYVDEYTIDLGKLEPLVAAPHSVDNVKTVNEVEG 286 Query: 369 VKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSL 527 + +D+V+IGSCT G+ DF AAK+ GK+VK +PA+ ++ L Sbjct: 287 LDVDQVFIGSCTNGRISDFEIAAKIL--KGKRVKSRCIAIPASYDLFKKAMEL 337
>LEU2_BACAN (Q81T66) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 98.2 bits (243), Expect = 1e-20 Identities = 68/196 (34%), Positives = 97/196 (49%), Gaps = 35/196 (17%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL ++ + V+ T MEF G TI ++ MEERMTLCNM IE G K G++ DE T Sbjct: 179 AKDIILHLLSKYGVAVGTGYVMEFYGETIGTMEMEERMTLCNMAIEGGAKAGIIAPDEKT 238 Query: 204 FKYLEGKTSV--EYE-------PVYSDAQARFYSDYRFDVSKLEPVVAKPHSP------- 335 F Y++G+ +YE +Y+DA A + DV+ L P V +P Sbjct: 239 FAYVKGRKYAPRDYETFEKKWFELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRID 298 Query: 336 ----------DNRALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKK 464 D RA + + D+ + V+IGSCT + D AA V G+K Sbjct: 299 EKLPEKHDVNDERAFSYMGLIPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASV--VKGRK 356 Query: 465 VK--VPTFLVPATQKV 506 VK V +VP +++V Sbjct: 357 VKEGVRALVVPGSKRV 372
>LEU2_RHIRA (P17279) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 644 Score = 98.2 bits (243), Expect = 1e-20 Identities = 72/220 (32%), Positives = 106/220 (48%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + +KD++L IIG I +G T +EF G TI +L+ME RM++CNM IEAG + G+V Sbjct: 229 PGVTSKDIVLHIIGVIGTAGGTGCVIEFCGDTIAALSMESRMSICNMSIEAGARAGMVAP 288 Query: 192 DETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVV------- 317 DE TF+YL K +V+Y + + SDA A++ + + + + P + Sbjct: 289 DEVTFEYLRDKPLAPKGADWDRAVKYWKSLSSDADAKYDINVEINAADIAPTLTWGTSPQ 348 Query: 318 ------------AKPHSPDNRALARECKD------------VKIDRVYIGSCTGGKTEDF 425 AK P R+ + D VK+D+V+IGSCT + ED Sbjct: 349 DVVPITGSTPDPAKIEDPIRRSAVQRALDYIGIAPNTPMEGVKVDKVFIGSCTNSRIEDL 408 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA V GK+ W+D ++ VPGSG Sbjct: 409 RAAAAV--VKGKRA-----------AEWVD--AMVVPGSG 433
>LEU2_RHOBA (Q7UIA7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 485 Score = 98.2 bits (243), Expect = 1e-20 Identities = 70/208 (33%), Positives = 101/208 (48%), Gaps = 40/208 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ + AKD+IL +IG+I +G T +EF G + +LTMEERMT+CNM IEAG + G+ Sbjct: 192 ELARGVTAKDMILYLIGQIGTAGGTGYVLEFTGDAVRNLTMEERMTVCNMSIEAGARAGM 251 Query: 183 VPADETTFKYLEGK--------TSVE-YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP 335 + D+TTF YL G+ +VE ++ + SD A + + S + P V +P Sbjct: 252 IAPDQTTFDYLRGRPECPADFDAAVEAWKKLPSDPGATYDRSNLYKGSDIRPQVTWGTNP 311 Query: 336 ----------------------DNRALARECKDVK---------IDRVYIGSCTGGKTED 422 + A A + D+K I+RV+IGSCT + ED Sbjct: 312 GQVCSVDSVVPSPGDSTDVNVQKSTASALQYMDLKAGTPITEIEINRVFIGSCTNARIED 371 Query: 423 FIAAAKVFLASGKKVKVPTFLVPATQKV 506 AAA V KV +VP + KV Sbjct: 372 LRAAAAVIKGHHCSDKVNAMIVPGSGKV 399
>LEU2_ANASP (Q8YX02) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 97.8 bits (242), Expect = 2e-20 Identities = 68/208 (32%), Positives = 99/208 (47%), Gaps = 43/208 (20%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD+IL II + V G + E+ G+T E + MEERMT+CNM IE G + G V Sbjct: 177 PGVYAKDVILHIIRTLGVKGGVGYAYEYAGTTFEQMNMEERMTVCNMAIEGGARCGYVNP 236 Query: 192 DETTFKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP- 335 D+ T+ YL+G K +E + SDA A + F+ + + P V +P Sbjct: 237 DQVTYDYLQGRDFAPQGADWEKAVTWWESIKSDADAEYDDVIVFNAADIPPTVTWGITPG 296 Query: 336 -----------------DNRALAREC------------KDVKIDRVYIGSCTGGKTEDFI 428 ++R +A E K KID +IGSCT G+ D Sbjct: 297 QGIGVNQLIPQPEELLEEDRFVAEEAYRYMDLYPGQPIKGTKIDVCFIGSCTNGRLTDLQ 356 Query: 429 AAAKVFLASGKKVK--VPTFLVPATQKV 506 AAK+ A G++V V F+VP +++V Sbjct: 357 EAAKI--AKGRRVAAGVKAFVVPGSERV 382
>LEU2_NITEU (Q82WI9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 97.8 bits (242), Expect = 2e-20 Identities = 66/197 (33%), Positives = 100/197 (50%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++PP + AKD+ L +IGEI +G T ++EF GS I SL+ME RMTLCNM IEAG + G+ Sbjct: 175 DLPPGVTAKDIALAVIGEIGTAGGTGYAIEFAGSAIRSLSMEGRMTLCNMAIEAGARAGM 234 Query: 183 VPADETTFKYLEGKTSVEYEPVYSDAQARFYS-----DYRFD-VSKLEPVVAKP------ 326 V ADE T Y++G+ ++ A A + + D FD + +L+ V KP Sbjct: 235 VGADEVTIDYIKGRPFAPQGALWDQAVAYWRTLKSDEDAVFDRMVELKAVNIKPQVTWGT 294 Query: 327 ----------HSPDNRALARECK--------------------DVKIDRVYIGSCTGGKT 416 + PD ++ K ++ +D+V+IGSCT + Sbjct: 295 SPEMVTTVDGYVPDPADISDPTKRHDVEHALGYMGLKPKMPIQEITLDKVFIGSCTNSRI 354 Query: 417 EDFIAAAKVFLASGKKV 467 ED AAA++ GK++ Sbjct: 355 EDLRAAAEI--VKGKRI 369
>LEU2_ASHGO (Q74ZM9) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 776 Score = 97.8 bits (242), Expect = 2e-20 Identities = 73/223 (32%), Positives = 105/223 (47%), Gaps = 43/223 (19%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 + P + +KDLIL IIG I +G T +EF G I+ LTME RM++CNM IEAG + G++ Sbjct: 184 LSPGITSKDLILHIIGVIGTAGGTGCVIEFTGQAIQELTMEARMSMCNMAIEAGARAGMI 243 Query: 186 PADETTFKYLEGK----TSVEYE-------PVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DETTF+YL+G+ T E+E + +D A F + + P + S Sbjct: 244 QPDETTFEYLKGRPLAPTGAEWEKAVTYWKTLKTDEDAVFDISVTVKGADIRPTITWGTS 303 Query: 333 PDNRALAREC--------------------------------KDVKIDRVYIGSCTGGKT 416 P + AL + KD+KID+V+IGSCT + Sbjct: 304 PQD-ALPIDAAVPDPANVSDPIKRSGMEAALEYMGLEPNTLLKDIKIDKVFIGSCTNARI 362 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA V G ++ P ++ ++ VPGSG Sbjct: 363 EDLRAAAAV--VDGHRI------APTVKR------AMVVPGSG 391
>LEU2_SYNEL (Q8DKF0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 97.8 bits (242), Expect = 2e-20 Identities = 70/204 (34%), Positives = 95/204 (46%), Gaps = 43/204 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL +I + V G + EF G+T L+MEERMT+CNM IE G + G V DETT Sbjct: 183 AKDVILHVIRHLGVKGGVGYAYEFAGTTFGQLSMEERMTVCNMAIEGGARCGYVNPDETT 242 Query: 204 FKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 F YL+G+ + + SDA A + F + + P V +P Sbjct: 243 FAYLKGRPFAPQGKAWDEAVAWWRSLASDADAEYDDVVTFAAADIAPTVTWGITPGQSVA 302 Query: 339 --------------NRALAREC------------KDVKIDRVYIGSCTGGKTEDFIAAAK 440 RA+A E + KID +IGSCT G+ D AAK Sbjct: 303 VDETLPTLESLPVAERAIAAEAYAYMDLQPGQPIQGTKIDVCFIGSCTNGRISDLRQAAK 362 Query: 441 VFLASGKKVK--VPTFLVPATQKV 506 V G+KVK V F+VP +++V Sbjct: 363 V--VEGRKVKPGVKAFVVPGSERV 384
>LEU2_BACHK (Q6HLF1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 97.8 bits (242), Expect = 2e-20 Identities = 68/196 (34%), Positives = 97/196 (49%), Gaps = 35/196 (17%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL ++ + V+ T MEF G TI ++ MEERMTLCNM IE G K G++ DE T Sbjct: 179 AKDIILHLLSKYGVAVGTGYVMEFYGETIGAMEMEERMTLCNMAIEGGAKAGIIAPDEKT 238 Query: 204 FKYLEGKTSV--EYE-------PVYSDAQARFYSDYRFDVSKLEPVVAKPHSP------- 335 F Y++G+ +YE +Y+DA A + DV+ L P V +P Sbjct: 239 FVYVKGRKYAPRDYETFEKKWFELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRID 298 Query: 336 ----------DNRALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKK 464 D RA + + D+ + V+IGSCT + D AA V G+K Sbjct: 299 EKLPEKHDVNDERAFSYMGLIPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASV--VKGRK 356 Query: 465 VK--VPTFLVPATQKV 506 VK V +VP +++V Sbjct: 357 VKEGVRALVVPGSKRV 372
>LEU2_BACCZ (Q63DX6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 97.8 bits (242), Expect = 2e-20 Identities = 66/196 (33%), Positives = 96/196 (48%), Gaps = 35/196 (17%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL ++ + V+ T MEF G TI ++ MEERMTLCNM IE G K G++ DE T Sbjct: 179 AKDIILHLLSKYGVAVGTGYVMEFYGETIGAMEMEERMTLCNMAIEGGAKAGIIAPDEKT 238 Query: 204 FKYLEGKT---------SVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP------- 335 F Y++G+ ++ +Y+DA A + DV+ L P V +P Sbjct: 239 FAYVKGRKYAPRDYETFEKKWSELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRID 298 Query: 336 ----------DNRALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKK 464 D RA + + D+ + V+IGSCT + D AA V G+K Sbjct: 299 EKLPEKHDVNDERAFSYMGLSPGQSTYDIPVQHVFIGSCTNSRLSDLEIAAAV--VKGRK 356 Query: 465 VK--VPTFLVPATQKV 506 VK V +VP +++V Sbjct: 357 VKEGVRALVVPGSKRV 372
>LEU2_BACC1 (Q73B98) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 97.8 bits (242), Expect = 2e-20 Identities = 65/196 (33%), Positives = 96/196 (48%), Gaps = 35/196 (17%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL ++ + V+ T MEF G TI+++ MEERMTLCNM IE G K G++ DE T Sbjct: 179 AKDIILHLLSKYGVAVGTGYVMEFYGETIQAMEMEERMTLCNMAIEGGAKAGIIAPDEKT 238 Query: 204 FKYLEGKT---------SVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP------- 335 Y++G+ ++ +Y+DA A + DV+ L P V +P Sbjct: 239 VAYVKGRKYAPKDYETFEKKWSELYTDADAMYDLHISIDVTDLAPYVTWGTNPSMGVRID 298 Query: 336 ----------DNRALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKK 464 D RA + + D+ + V+IGSCT + D AA V G+K Sbjct: 299 EKLPEKHDVNDERAFSYMGLSPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASV--VKGRK 356 Query: 465 VK--VPTFLVPATQKV 506 VK V +VP +++V Sbjct: 357 VKEGVRALVVPGSKRV 372
>LEU2_STAAW (P58947) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 97.8 bits (242), Expect = 2e-20 Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 32/199 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I V T ++EF G TI++L+M+ RMT+CNM IE G K G++ Sbjct: 173 LPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGII 232 Query: 186 PADETTFKYLEG--------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 D+ TF+Y++G K+ ++ +YSD A F DVS LEP V +P Sbjct: 233 QPDDITFEYVKGRPFADNFVKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+ + V++GSCT + D I A+ + Sbjct: 293 GVNFSEPFPEISDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVK 352 Query: 450 ASGKKVKVPTFLVPATQKV 506 + + +VP ++ V Sbjct: 353 GNKVHPNITAIVVPGSRTV 371
>LEU2_STAAS (Q6G7P9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 97.8 bits (242), Expect = 2e-20 Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 32/199 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I V T ++EF G TI++L+M+ RMT+CNM IE G K G++ Sbjct: 173 LPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGII 232 Query: 186 PADETTFKYLEG--------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 D+ TF+Y++G K+ ++ +YSD A F DVS LEP V +P Sbjct: 233 QPDDITFEYVKGRPFADNFVKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+ + V++GSCT + D I A+ + Sbjct: 293 GVNFSEPFPEISDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVK 352 Query: 450 ASGKKVKVPTFLVPATQKV 506 + + +VP ++ V Sbjct: 353 GNKVHPNITAIVVPGSRTV 371
>LEU2_STAAN (P63436) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 97.8 bits (242), Expect = 2e-20 Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 32/199 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I V T ++EF G TI++L+M+ RMT+CNM IE G K G++ Sbjct: 173 LPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGII 232 Query: 186 PADETTFKYLEG--------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 D+ TF+Y++G K+ ++ +YSD A F DVS LEP V +P Sbjct: 233 QPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+ + V++GSCT + D I A+ + Sbjct: 293 GVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVK 352 Query: 450 ASGKKVKVPTFLVPATQKV 506 + + +VP ++ V Sbjct: 353 GNKVHPNITAIVVPGSRTV 371
>LEU2_STAAM (P63435) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 97.8 bits (242), Expect = 2e-20 Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 32/199 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I V T ++EF G TI++L+M+ RMT+CNM IE G K G++ Sbjct: 173 LPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGII 232 Query: 186 PADETTFKYLEG--------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 D+ TF+Y++G K+ ++ +YSD A F DVS LEP V +P Sbjct: 233 QPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+ + V++GSCT + D I A+ + Sbjct: 293 GVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVK 352 Query: 450 ASGKKVKVPTFLVPATQKV 506 + + +VP ++ V Sbjct: 353 GNKVHPNITAIVVPGSRTV 371
>LEU2_STAAC (Q5HEE2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 456 Score = 97.8 bits (242), Expect = 2e-20 Identities = 61/199 (30%), Positives = 98/199 (49%), Gaps = 32/199 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I V T ++EF G TI++L+M+ RMT+CNM IE G K G++ Sbjct: 173 LPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGII 232 Query: 186 PADETTFKYLEG--------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 D+ TF+Y++G K+ ++ +YSD A F DVS LEP V +P Sbjct: 233 QPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+ + V++GSCT + D I A+ + Sbjct: 293 GVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVK 352 Query: 450 ASGKKVKVPTFLVPATQKV 506 + + +VP ++ V Sbjct: 353 GNKVHPNITAIVVPGSRTV 371
>LEU2_PHYBL (P18250) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 744 Score = 97.8 bits (242), Expect = 2e-20 Identities = 71/223 (31%), Positives = 106/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + +KD+ L +IG I +G T +EF GS I SL+ME RM++CNM IE G + G+ Sbjct: 167 ELTPGVTSKDVALHVIGLIGTAGGTRCVIEFCGSAIASLSMEARMSICNMSIEGGARAGM 226 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE TF+YL G+ +V+Y + + SD A++ D + S + P + Sbjct: 227 IAPDEITFEYLRGRPLAPEGAEWDKAVQYWKSLKSDPNAKYDIDVKIAASDIAPTITWGT 286 Query: 330 SPDN------------------RALARE-------------CKDVKIDRVYIGSCTGGKT 416 SP + R A E ++VKID+ +IGSCT + Sbjct: 287 SPQDVAPITANVPDPSSVSDPARKAAMERALEYIGLVPNTPLEEVKIDKAFIGSCTNSRI 346 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +AA + GK + W VY++ VPGSG Sbjct: 347 EDLRSAASI--VKGKHI-----------ADW--VYAMVVPGSG 374
>LEU2_VIBVU (Q8DED9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 97.1 bits (240), Expect = 3e-20 Identities = 66/207 (31%), Positives = 105/207 (50%), Gaps = 44/207 (21%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ + +G T +EF G I L+ME RMT+CNM IE G K G++ D+ Sbjct: 178 ITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLSMEGRMTVCNMAIELGAKAGLIAPDQ 237 Query: 198 TTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDN- 341 TTF Y++G+ +VEY + + +D A+F + + + ++P V +P Sbjct: 238 TTFDYIKGRKFAPTGADWDAAVEYWKTLKTDEDAKFDAVVTLNAADIKPQVTWGTNPGQV 297 Query: 342 -----------------------RALA-------RECKDVKIDRVYIGSCTGGKTEDFIA 431 +ALA + + K+D+V++GSCT + ED A Sbjct: 298 IAVDEPIPAPESFSDPVEKASAEKALAYMGLEAGKSLSEYKVDKVFVGSCTNSRIEDMRA 357 Query: 432 AAKVFLASGKKV--KVPTFLVPATQKV 506 AA V A G+KV V +VP +++V Sbjct: 358 AAVV--AKGRKVASHVQALIVPGSEQV 382
>LEU2_SHISS (Q3Z5T8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 97.1 bits (240), Expect = 3e-20 Identities = 72/220 (32%), Positives = 100/220 (45%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I L+ME RMTLCNM IE G K G+V Sbjct: 176 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKTGLVAP 235 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVV------- 317 DETTF Y++G+ ++ + +D A F + ++ P V Sbjct: 236 DETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPG 295 Query: 318 ----AKPHSPDNRALARECK--------------------DVKIDRVYIGSCTGGKTEDF 425 + PD + A K +V ID+V+IGSCT + ED Sbjct: 296 QVISVNDNIPDPASFADPVKRASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA++ A G+KV P Q +L VPGSG Sbjct: 356 RAAAEI--AKGRKV------APGVQ-------ALVVPGSG 380
>LEU2_LISMF (Q71Y33) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 97.1 bits (240), Expect = 3e-20 Identities = 62/201 (30%), Positives = 101/201 (50%), Gaps = 34/201 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I V+ T ++E+ G TI +++MEERMT+CNM IE G K G++ Sbjct: 173 LPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNMAIEGGAKMGMM 232 Query: 186 PADETTFKYLEG---------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD 338 DETTF+Y+ G K +++ + +D A + + D S LEP V +P+ Sbjct: 233 APDETTFEYVRGREYAPADMDKAISDWKTLQTDPDAEYDLHIKMDASILEPYVTWGTNPE 292 Query: 339 -----NRALARECKDVKIDR--------------------VYIGSCTGGKTEDFIAAAKV 443 ++A E KD+ +R V+IGSCT + D AA++ Sbjct: 293 MGVPFSKAFP-EIKDMNYERAYEYMGLKPGQTAEEIELGYVFIGSCTNARLSDLEEAARI 351 Query: 444 FLASGKKVKVPTFLVPATQKV 506 + K + +VP +++V Sbjct: 352 VKGNKVKNNIRALVVPGSRQV 372
>LEU2_USTMA (P49601) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 773 Score = 97.1 bits (240), Expect = 3e-20 Identities = 68/224 (30%), Positives = 105/224 (46%), Gaps = 43/224 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ + +KD+IL IIG I +G T +E+ GSTI SL+ME RM++CNM IEAG + G+ Sbjct: 180 ELSQGVTSKDIILHIIGLIGTAGGTGHVIEYAGSTIRSLSMEARMSICNMSIEAGARAGL 239 Query: 183 VPADETTFKYLEGK------------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVA-- 320 + DE T++Y++G+ ++ + SD A++ + + D + P V Sbjct: 240 IAPDEITYEYIKGRPLAPKQGEAWDQALAYWKTLPSDEGAQYDTVIKIDAKDIPPTVTWG 299 Query: 321 --------------KPHSPDNRALAR---------------ECKDVKIDRVYIGSCTGGK 413 P + N A A+ + +KID+V+IGSCT + Sbjct: 300 TSPQDVVAITGTVPDPKNASNEAEAKAWTRALEYMGLEAGTPMEKIKIDKVFIGSCTNAR 359 Query: 414 TEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA+V +KV +Y + VPGSG Sbjct: 360 IEDLRAAARVLHG---------------RKVADGLYCMLVPGSG 388
>LEU2_LEIXX (Q6AFK7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 486 Score = 97.1 bits (240), Expect = 3e-20 Identities = 67/213 (31%), Positives = 98/213 (46%), Gaps = 42/213 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + AKD+IL +I +I G +E+ GS I +L+ME RMT+CNM IEAG + G+ Sbjct: 179 ELRPGVTAKDIILAVIAKIGTGGGQGYVLEYRGSAIRALSMEGRMTVCNMSIEAGARAGM 238 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVV---- 317 V DETTF YL+G+ + + +D A F ++ D ++EP V Sbjct: 239 VAPDETTFAYLKGRPHAPEGEDWDEAVAYWTTLQTDDAAVFDAEVFLDAGEIEPFVTWGT 298 Query: 318 ---------------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKT 416 A P+ RA A K V +D V++GSCT + Sbjct: 299 NPGQGVSLSQDVPDPADIEEPNARAAAERALEYMDLKSGTPMKSVPVDAVFMGSCTNSRI 358 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMD 515 ED A A V K V +VP + +V ++ Sbjct: 359 EDLRAFASVIKGRKKAEGVRVMVVPGSARVRLE 391
>LEU2_VIBVY (Q7MP79) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 96.7 bits (239), Expect = 4e-20 Identities = 66/207 (31%), Positives = 105/207 (50%), Gaps = 44/207 (21%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ + +G T +EF G I L+ME RMT+CNM IE G K G++ D+ Sbjct: 178 ITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLSMEGRMTVCNMAIELGAKAGLIAPDK 237 Query: 198 TTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDN- 341 TTF Y++G+ +VEY + + +D A+F + + + ++P V +P Sbjct: 238 TTFDYIKGRKFAPTGADWDAAVEYWKTLKTDEDAKFDAVVTLNAADIKPQVTWGTNPGQV 297 Query: 342 -----------------------RALA-------RECKDVKIDRVYIGSCTGGKTEDFIA 431 +ALA + + K+D+V++GSCT + ED A Sbjct: 298 IAVDEPIPAPESFSDPVEKASAEKALAYMGLEAGKSLSEYKVDKVFVGSCTNSRIEDMRA 357 Query: 432 AAKVFLASGKKV--KVPTFLVPATQKV 506 AA V A G+KV V +VP +++V Sbjct: 358 AAVV--AKGRKVASHVQALIVPGSEQV 382
>LEU2_SILPO (Q5LX06) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 96.7 bits (239), Expect = 4e-20 Identities = 67/222 (30%), Positives = 104/222 (46%), Gaps = 41/222 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + AKD+ L +IG +G T +E+ G I L+ME RMT+CNM IE G + G+ Sbjct: 176 KLNPGVTAKDITLAVIGATGTAGGTGYVIEYCGEAIRDLSMEGRMTVCNMAIEGGARAGL 235 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D+TTF Y++G+ ++ +YSD A F ++EPVV Sbjct: 236 IAPDQTTFDYVKGRPHAPKGAQWEAALAWWKTLYSDDGAHFDKIVTLKGEEIEPVVTWGT 295 Query: 330 SPDN-----------------------RAL-------ARECKDVKIDRVYIGSCTGGKTE 419 SP++ R++ ++ D++ID V+IGSCT G+ E Sbjct: 296 SPEDVLPITGVVPSPEDFTGGKVEAARRSIEYMGLTPGQKLTDIEIDTVFIGSCTNGRIE 355 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D A A+V GKK+K + ++ VPGSG Sbjct: 356 DLRAVAEV--VKGKKIK-------------SGLRAMVVPGSG 382
>LEU2_HAEIN (P44968) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 96.7 bits (239), Expect = 4e-20 Identities = 72/218 (33%), Positives = 99/218 (45%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD+IL IIG+ +++G T +EF G I+ L+ME RMT+CNM IE G K G++ DE Sbjct: 177 ITAKDIILAIIGKTTMAGGTGHVVEFCGEAIQDLSMEGRMTVCNMAIEMGAKAGLIAPDE 236 Query: 198 TTFKYLEGKTSVEYEPVYSDAQARFYS-----DYRFD----------------------- 293 TTF YL+ + + DA A + + D +FD Sbjct: 237 TTFAYLKDRPHAPKGKDWEDAVAYWKTLKSDDDAQFDTVVTLEAKDIAPQVTWGTNPGQV 296 Query: 294 --VSKLEPVVAKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIA 431 V++ P + P RA A + KD+K+D+V+IGSCT + ED A Sbjct: 297 ISVNETIPNPQEMADPVQRASAEKALHYIGLEAGTNLKDIKVDQVFIGSCTNSRIEDLRA 356 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AA V K V LV VPGSG Sbjct: 357 AAAVMKGRKKADNVKRILV--------------VPGSG 380
>LEU2_LISIN (Q92A26) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 462 Score = 96.3 bits (238), Expect = 6e-20 Identities = 62/202 (30%), Positives = 101/202 (50%), Gaps = 34/202 (16%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + AKD+IL +I V+ T ++E+ G TI +++MEERMT+CNM IE G K G+ Sbjct: 172 KLPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNMAIEGGAKMGM 231 Query: 183 VPADETTFKYLEG---------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP 335 + D+TTF+Y+ G K ++E + +D A + D S LEP V +P Sbjct: 232 MAPDQTTFEYVRGREYAPSDMEKAIRDWETLKTDPDAEYDLHIEMDASILEPYVTWGTNP 291 Query: 336 D-----NRALARECKDVKIDR--------------------VYIGSCTGGKTEDFIAAAK 440 + ++A E KD+ +R V+IGSCT + D AA+ Sbjct: 292 EMGVPFSKAFP-EIKDMNYERAYEYMGLKPGQTAEEIELGYVFIGSCTNARLSDLEEAAR 350 Query: 441 VFLASGKKVKVPTFLVPATQKV 506 + + K + +VP +++V Sbjct: 351 IVKGNKVKNNIRALVVPGSRQV 372
>LEU2_SULSO (Q97VY2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 416 Score = 96.3 bits (238), Expect = 6e-20 Identities = 53/167 (31%), Positives = 88/167 (52%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ KD+ L+++G+ ++E S M+ R T+ NM IE + D Sbjct: 171 WITGKDVALKLLGDFKADYFNGMTLEIFVKDPLSFPMDYRATVSNMGIEMNADALMFIPD 230 Query: 195 ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVK 374 + T +Y++ E E V D A++ +Y + ++EP+VA PHS DN + E + Sbjct: 231 QETKRYIKEMRGYEPELVTPDNGAKYVDEYTIQLDEMEPLVAAPHSVDNVKVVNELEGTP 290 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMD 515 +D+VYIGSCT G+ DF AAK+ GKKVK +PA+ +++ + Sbjct: 291 VDQVYIGSCTNGRLSDFEIAAKIM--KGKKVKSRCIAIPASYRMFKE 335
>LEU2_RALEJ (Q46YV7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 96.3 bits (238), Expect = 6e-20 Identities = 71/223 (31%), Positives = 102/223 (45%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P AKD++L IIG+I +G T ++EF GS I LTME RMT+CNM IEAG + G+ Sbjct: 173 KLPRGCTAKDIVLAIIGKIGTAGGTGYTIEFAGSAIRDLTMEGRMTVCNMAIEAGARAGL 232 Query: 183 VPADETTFKYLEGK----TSVEYE-------PVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D T +Y++G+ VE++ ++SDA A F + P V Sbjct: 233 VAVDNVTLEYVKGRPYAPQGVEWDQAVAYWSTLHSDAGASFDQVIELRAEDIRPQVTWGT 292 Query: 330 SPD--------------------NRALAR-----------ECKDVKIDRVYIGSCTGGKT 416 SP+ A+ R + + +D+V+IGSCT + Sbjct: 293 SPEMVVSIEDRVPDPEKEKDPTRRNAMERALEYMNLQPNVPMESINVDKVFIGSCTNSRI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAA V G+KV L ++ VPGSG Sbjct: 353 EDMRAAAWVVQKLGRKVASNVKL------------AMVVPGSG 383
>LEU2_XANOR (Q5H4D1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 482 Score = 96.3 bits (238), Expect = 6e-20 Identities = 72/222 (32%), Positives = 105/222 (47%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GS I +L+ME RMT+CNM IEAG + G+V Sbjct: 180 LPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRALSMEGRMTICNMSIEAGARVGMV 239 Query: 186 PADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DE T Y++G+ + + SD A F + ++P V+ S Sbjct: 240 AVDEKTIAYVKGRPFAPKGADWDAAVALWSTLVSDPDAHFDTVVELHAEDIKPQVSWGTS 299 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P+ RAL + D+++DRV+IGSCT + E Sbjct: 300 PEMVLAIDQHVPDPATEQDPTKRNSIERALKYMGLKANQAITDIRLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA V A G+K V +T K +L VPGSG Sbjct: 360 DLRAAAAV--AKGRK-------VASTIK-----QALVVPGSG 387
>LEU2_BACSK (Q5WEN5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 95.9 bits (237), Expect = 7e-20 Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL II + V T +EF G I +TMEERMT+CNM IEAG K G++ D+ T Sbjct: 179 AKDVILAIIAKFGVDIGTGSIIEFTGEAIRGMTMEERMTICNMSIEAGAKAGLISPDQVT 238 Query: 204 FKYLEGKTSVEYEPVY-----------SDAQARFYSDYRFDVSKLEPVVAKPHSP----- 335 F YL+G+ +V Y +D A + D +++EP+V +P Sbjct: 239 FDYLQGRANVPKGEAYDEIVEKWAQLATDPGATYDRSVTIDAAEIEPMVTWGTNPGQGAG 298 Query: 336 ---------------DNRALAR-----------ECKDVKIDRVYIGSCTGGKTEDFIAAA 437 + RA+++ +++I V+IGSCT + D AAA Sbjct: 299 ISKAVPRLDDAKSEVERRAISQALDYMDIKPGTPLSEIEIQHVFIGSCTNSRLSDLRAAA 358 Query: 438 KVFLASGKKVK--VPTFLVPATQKV 506 V +G+KV V +VP +Q+V Sbjct: 359 AVI--NGRKVAPGVRALIVPGSQRV 381
>LEU2_SYNY3 (P54384) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 95.9 bits (237), Expect = 7e-20 Identities = 65/209 (31%), Positives = 95/209 (45%), Gaps = 41/209 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + AKD+IL II ++ V G + E+ GST ++ MEERMT+CNM IE G + G Sbjct: 174 DLAPGVYAKDVILHIIRKLGVKGGVGYAYEYAGSTFVAMNMEERMTVCNMSIEGGARCGY 233 Query: 183 VPADETTFKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVA--- 320 + DE TF YL+G K + + S+ A + F +EP V Sbjct: 234 INPDEVTFAYLKGREFAPQGEDWDKAVQWWRSIASEPDAVYDDVVSFRAEDIEPTVTWGI 293 Query: 321 ---------------KPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTE 419 +PD++A+A E K K+D +IGSCT G+ Sbjct: 294 TPGQGIGISEPVPTLDSLNPDDQAIASEAYKYMQFQPGQPLKGTKVDVCFIGSCTNGRLS 353 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKV 506 D AAKV V F+VP +++V Sbjct: 354 DLEEAAKVAKGHQVAAGVKAFVVPGSEQV 382
>LEU2_STAAR (Q6GF14) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 455 Score = 95.9 bits (237), Expect = 7e-20 Identities = 60/199 (30%), Positives = 98/199 (49%), Gaps = 32/199 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I V T ++EF G TI++L+M+ RMT+CNM IE G K G++ Sbjct: 173 LPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGII 232 Query: 186 PADETTFKYLEG--------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 D+ TF+Y++G K+ ++ +YS+ A F DVS LEP V +P Sbjct: 233 QPDDITFEYVKGRPFADNFAKSVDKWRELYSNDDAIFDRVIELDVSTLEPQVTWGTNPEM 292 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+ + V++GSCT + D I A+ + Sbjct: 293 GVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVK 352 Query: 450 ASGKKVKVPTFLVPATQKV 506 + + +VP ++ V Sbjct: 353 GNKVHPNITAIVVPGSRTV 371
>LEU2_HAEI8 (Q4QLS2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 95.9 bits (237), Expect = 7e-20 Identities = 72/218 (33%), Positives = 98/218 (44%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD+IL IIG+ +++G T +EF G I L+ME RMT+CNM IE G K G++ DE Sbjct: 178 ITAKDIILAIIGKTTMAGGTGHVVEFCGEAIRDLSMEGRMTVCNMAIEMGAKAGLIAPDE 237 Query: 198 TTFKYLEGKTSVEYEPVYSDAQARFYS-----DYRFD----------------------- 293 TTF YL+ + + DA A + + D +FD Sbjct: 238 TTFAYLKDRPHAPKGKDWDDAVAYWKTLKSDDDAQFDTVVTLEAKDIAPQVTWGTNPGQV 297 Query: 294 --VSKLEPVVAKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIA 431 V++ P + P RA A + KD+K+D+V+IGSCT + ED A Sbjct: 298 ISVNETIPNPQEMADPVQRASAEKALHYIGLEAGTNLKDIKVDQVFIGSCTNSRIEDLRA 357 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AA V K V LV VPGSG Sbjct: 358 AAAVMKGRKKADNVKRILV--------------VPGSG 381
>LEU2_BACTN (Q8A6L7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 95.9 bits (237), Expect = 7e-20 Identities = 65/211 (30%), Positives = 103/211 (48%), Gaps = 41/211 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ + AKD+ L ++ +++ SGAT +E+ GS I +LTME R+TLCN+ IE G + G+ Sbjct: 172 ELGKGVTAKDVALYMMSKMTTSGATGYFVEYAGSAIRNLTMEGRLTLCNLSIEMGARGGM 231 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVA--- 320 V DE TF+Y++G+ ++EY + + SD A F + RFD + +EP++ Sbjct: 232 VAPDEVTFEYIKGRENAPQGEAWDQAMEYWKTLKSDDDAVFDQEVRFDAADIEPMITYGT 291 Query: 321 --------KPHSPDNRALARECK-------------------DVKIDRVYIGSCTGGKTE 419 + P + + KID V++G+CT G+ E Sbjct: 292 NPGMGMGITQNIPTTEGMGEAAQVSFKKSMEYMGFQPGESLLGKKIDYVFLGACTNGRIE 351 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWM 512 DF A A + K V +LVP + WM Sbjct: 352 DFRAFASLVKGRRKADNVIAWLVPGS---WM 379
>LEU2_BACHD (Q9K8F0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 95.9 bits (237), Expect = 7e-20 Identities = 67/212 (31%), Positives = 102/212 (48%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + AKD+IL +I + V T +EF G I SL+MEERMT+CNM IEAG K G+ Sbjct: 173 ELAPSVSAKDIILAVIAKYGVDFGTGHVIEFTGEAIRSLSMEERMTICNMSIEAGAKAGL 232 Query: 183 VPADETTFKYLEGKTSV-----------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D TF+YL G+ + ++E + +DA A + + S++EP+V Sbjct: 233 ISPDSVTFEYLRGRPNAPKGEAFDVAIQQWEALATDAGAVYDRVLTMNASEIEPMVTWGT 292 Query: 330 SP--------------------DNRALARE-----------CKDVKIDRVYIGSCTGGKT 416 +P + RA+ + ++ I V+IGSCT + Sbjct: 293 NPAQGTGVSQVVPSPDDAKDENERRAIKQSLAYMGLEPGTPITEIAIQHVFIGSCTNSRL 352 Query: 417 EDFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 D AA+ L G+KV V +VP +Q+V Sbjct: 353 SDLRTAAE--LIKGRKVADGVRALVVPGSQQV 382
>LEU2_ECOLI (P0A6A6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 95.9 bits (237), Expect = 7e-20 Identities = 73/220 (33%), Positives = 100/220 (45%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I L+ME RMTLCNM IE G K G+V Sbjct: 175 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAP 234 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVV------- 317 DETTF Y++G+ ++ + +D A F + ++ P V Sbjct: 235 DETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPG 294 Query: 318 ------------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 A P RA A + +V ID+V+IGSCT + ED Sbjct: 295 QVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDL 354 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA++ A G+KV P Q +L VPGSG Sbjct: 355 RAAAEI--AKGRKV------APGVQ-------ALVVPGSG 379
>LEU2_ECOL6 (P0A6A7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 95.9 bits (237), Expect = 7e-20 Identities = 73/220 (33%), Positives = 100/220 (45%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I L+ME RMTLCNM IE G K G+V Sbjct: 175 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAP 234 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVV------- 317 DETTF Y++G+ ++ + +D A F + ++ P V Sbjct: 235 DETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPG 294 Query: 318 ------------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 A P RA A + +V ID+V+IGSCT + ED Sbjct: 295 QVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDL 354 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA++ A G+KV P Q +L VPGSG Sbjct: 355 RAAAEI--AKGRKV------APGVQ-------ALVVPGSG 379
>LEU2_ECO57 (Q8XA00) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 95.9 bits (237), Expect = 7e-20 Identities = 73/220 (33%), Positives = 100/220 (45%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I L+ME RMTLCNM IE G K G+V Sbjct: 175 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAP 234 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVV------- 317 DETTF Y++G+ ++ + +D A F + ++ P V Sbjct: 235 DETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPG 294 Query: 318 ------------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 A P RA A + +V ID+V+IGSCT + ED Sbjct: 295 QVISVNDNIPDPASFADPVERASAEKALAYMGLKPGILLTEVAIDKVFIGSCTNSRIEDL 354 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA++ A G+KV P Q +L VPGSG Sbjct: 355 RAAAEI--AKGRKV------APGVQ-------ALVVPGSG 379
>LEU2_SHIBS (Q326G3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 95.9 bits (237), Expect = 7e-20 Identities = 73/220 (33%), Positives = 100/220 (45%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I L+ME RMTLCNM IE G K G+V Sbjct: 176 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAP 235 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVV------- 317 DETTF Y++G+ ++ + +D A F + ++ P V Sbjct: 236 DETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPG 295 Query: 318 ------------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 A P RA A + +V ID+V+IGSCT + ED Sbjct: 296 QVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA++ A G+KV P Q +L VPGSG Sbjct: 356 RAAAEI--AKGRKV------APGVQ-------ALVVPGSG 380
>LEU2_BLOPB (Q493R2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 95.9 bits (237), Expect = 7e-20 Identities = 66/207 (31%), Positives = 92/207 (44%), Gaps = 42/207 (20%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD+IL IIG+I G + +EF G I L+MEERMTLCNM IE G + ++ Sbjct: 176 PQITAKDIILAIIGKIGHGGGSGHVVEFCGPIITLLSMEERMTLCNMAIEMGATSALIAP 235 Query: 192 DETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD 338 D TT+ YL+ + + ++ +YSD A F + FDVS + P V +P Sbjct: 236 DRTTYDYLKNRKFSPTGKNWEQALLYWKTLYSDHDAHFDKKFDFDVSNVNPQVTWGTNPS 295 Query: 339 ------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTEDF 425 RAL DV ID+V+IGSCT + ED Sbjct: 296 QVISIDQPIPSLESFIDPIERNSAERALIYMKLQSNTYLTDVSIDKVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKV 506 AA+ +VP ++ V Sbjct: 356 RVAAQTIKGHHISKNTQAIVVPGSKLV 382
>LEU2_THIDA (Q3SHL1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 95.1 bits (235), Expect = 1e-19 Identities = 74/223 (33%), Positives = 105/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ + AKD+ L +IG I +G T ++EF G+ I +L+ME RMTLCNM IEAG + G+ Sbjct: 174 ELGKGVTAKDIALAVIGRIGTAGGTGYAIEFGGAAIRALSMEGRMTLCNMAIEAGARAGM 233 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V D+TT Y+EG+ T+V + + ++SDA A F D + +EP V Sbjct: 234 VAVDQTTIDYVEGRPYAPTGEAWDTAVAWWKTLHSDADAVFDRVVELDAAAIEPQVTWGT 293 Query: 330 SP-----------DNRALARECKD--------------------VKIDRVYIGSCTGGKT 416 SP D A E K + +D+V+IGSCT + Sbjct: 294 SPEMVTTVGASVPDPSAAPSEVKRQDWVRALEYMGLAAGTPVSAIALDKVFIGSCTNSRI 353 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AA V A G++V L ++ VPGSG Sbjct: 354 EDLREAAAV--AKGRRVAPNVKL------------AMVVPGSG 382
>LEU2_BIFLO (Q8G4W2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 467 Score = 95.1 bits (235), Expect = 1e-19 Identities = 67/211 (31%), Positives = 97/211 (45%), Gaps = 43/211 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P AKD+IL II +I G +E+ G I +LTM+ERMT+CNM IEAG + G+ Sbjct: 174 KLPADATAKDIILAIIAKIGTGGGQGYVIEYRGEAIRNLTMDERMTVCNMSIEAGARAGM 233 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+YL+G+ ++ + +D A F D +KL P V Sbjct: 234 IAPDETTFEYLKGRPHAPEGELWDQAVAYWKTLKTDDDAVFDKVVDIDATKLGPYVTWGT 293 Query: 330 SP-------------------DNRALAREC------------KDVKIDRVYIGSCTGGKT 416 +P RA A KD+ +D V+IGSCT G+ Sbjct: 294 NPGQGLPITASVPEPGKIADATKRAAAERAITYMGLKPGMPIKDIAVDTVFIGSCTNGRI 353 Query: 417 EDFIAAAKVFLASGKKVKVPTFL-VPATQKV 506 +D AA + K + L VPA+ +V Sbjct: 354 DDLRQAAAIMKGHRKAENIHRVLVVPASSRV 384
>LEU2_MYCTU (O53237) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 95.1 bits (235), Expect = 1e-19 Identities = 67/211 (31%), Positives = 101/211 (47%), Gaps = 44/211 (20%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I +I G +E+ GS IESL+ME RMT+CNM IEAG + G+V Sbjct: 181 LPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMV 240 Query: 186 PADETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DETT+ +L G+ V ++ + +D A F ++ D + L P V + Sbjct: 241 APDETTYAFLRGRPHAPTGAQWDTALVYWQRLRTDVGAVFDTEVYLDAASLSPFVTWGTN 300 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P +ALA +D+ +D V++GSCT G+ E Sbjct: 301 PGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTAMRDIAVDAVFVGSCTNGRIE 360 Query: 420 DFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 D A+V G+KV V +VP + +V Sbjct: 361 DLRVVAEVL--RGRKVADGVRMLIVPGSMRV 389
>LEU2_PHOPR (Q6LV26) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 95.1 bits (235), Expect = 1e-19 Identities = 70/207 (33%), Positives = 103/207 (49%), Gaps = 44/207 (21%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD++L IIG+ + +G T +EF G I LTME RMT+CNM IE G K G++ D+ Sbjct: 184 ITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVCNMAIELGAKAGLIAPDQ 243 Query: 198 TTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVV---AKP--- 326 TT+ Y++ + +VEY + +D A F + D ++P V P Sbjct: 244 TTYDYIKDRKFSPTGANFDAAVEYWSTLKTDDGATFDAVVTLDAKNIKPQVTWGTNPGQV 303 Query: 327 -------HSPDN-----------RALA-------RECKDVKIDRVYIGSCTGGKTEDFIA 431 PDN +ALA ++ D ID+V+IGSCT + ED A Sbjct: 304 IAIDELIPGPDNFSEQVDKTSAEKALAYMGLEAGKKLSDFDIDKVFIGSCTNSRIEDMRA 363 Query: 432 AAKVFLASGKKV--KVPTFLVPATQKV 506 AA + A G+KV V +VP +++V Sbjct: 364 AAAI--AKGRKVAANVQALVVPGSEQV 388
>LEU2_XYLFT (Q87BP9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 95.1 bits (235), Expect = 1e-19 Identities = 71/222 (31%), Positives = 104/222 (46%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GSTI +L+ME RMT+CNM IEAG + G+V Sbjct: 180 LPWGVTAKDIVLALIGKIGTAGGNGYAVEFSGSTIRALSMEGRMTICNMAIEAGARVGMV 239 Query: 186 PADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DE T +Y+ G+ + + SD A F +++P V S Sbjct: 240 AVDEKTIQYVHGRPFAPKGSDWDAAVAFWRGLVSDPDAHFDRVVELSAEEIKPQVTWGTS 299 Query: 333 PD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKTE 419 P+ +L R K +K+DRV+IGSCT + E Sbjct: 300 PEMVSAVDQSVPDPERETDPVKKESLIRALKYMGLQPNDPITSIKLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA+V G+K V +T K ++ VPGSG Sbjct: 360 DLRAAAEV--VKGRK-------VASTVK-----QAMVVPGSG 387
>LEU2_XYLFA (Q9PAX0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 95.1 bits (235), Expect = 1e-19 Identities = 71/222 (31%), Positives = 104/222 (46%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GSTI +L+ME RMT+CNM IEAG + G+V Sbjct: 180 LPWGVTAKDIVLALIGKIGTAGGNGYAVEFSGSTIRALSMEGRMTICNMAIEAGARVGMV 239 Query: 186 PADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DE T +Y+ G+ + + SD A F +++P V S Sbjct: 240 AVDEKTIQYVHGRPFAPKGSDWDAAVAFWRGLVSDPDAHFDRVVELSAEEIKPQVTWGTS 299 Query: 333 PD--------------------NRALARECK-----------DVKIDRVYIGSCTGGKTE 419 P+ +L R K +K+DRV+IGSCT + E Sbjct: 300 PEMVSAVDQSVPDPERETDPVKKESLIRALKYMGLQPNDPITSIKLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA+V G+K V +T K ++ VPGSG Sbjct: 360 DLRAAAEV--VKGRK-------VASTVK-----QAMVVPGSG 387
>LEU2_SHEON (Q8E9N4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 95.1 bits (235), Expect = 1e-19 Identities = 69/205 (33%), Positives = 100/205 (48%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD++L IIG+I + G T +EF G IE+L+ME RMT+CNM IE G K G+V D+TT Sbjct: 188 AKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMVAPDQTT 247 Query: 204 FKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVV----------- 317 F YLEG+ E++ + +D A F + D + + P + Sbjct: 248 FDYLEGREFAPKGEDWAQAVAEWKTLKTDVGAEFDATVVLDAADIAPQLTWGTNPGQVVA 307 Query: 318 --------AKPHSPDNRALARECKD------------VKIDRVYIGSCTGGKTEDFIAAA 437 A +P R+ + D V I++V+IGSCT + ED +AA Sbjct: 308 IDAPVPNPADEVNPTIRSSMEKALDYIGLTAGTPMTEVAINKVFIGSCTNSRIEDLRSAA 367 Query: 438 KVFLASGKKVK--VPTFLVPATQKV 506 K A G+KV V +VP + +V Sbjct: 368 K--HAKGRKVAAGVTAIVVPGSGQV 390
>LEU2_COLP3 (Q47WG2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 94.7 bits (234), Expect = 2e-19 Identities = 67/206 (32%), Positives = 100/206 (48%), Gaps = 45/206 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL IIG+ +GAT +E+ G IE+L+MEERMT+CNM IE G K G++ D+TT Sbjct: 184 AKDIILAIIGKTGSAGATGYVVEYCGEAIEALSMEERMTVCNMSIEFGAKAGLIAPDQTT 243 Query: 204 FKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFD----------------VSK 302 F Y+EGK V+++ + SDA A+F + D V Sbjct: 244 FDYVEGKEYAPKGEVFEQAVVDWKNLKSDADAQFDAVLTLDAKDIKAQVTWGTNPGQVIS 303 Query: 303 LEPVVAKPHSPDNRALAREC---------------KDVKIDRVYIGSCTGGKTEDFIAAA 437 ++ V P + C D+ +++V+IGSCT + ED AAA Sbjct: 304 VDGTVPSPEDFSDPVEKESCVSALNYMGLTAGTKMTDIHVNKVFIGSCTNSRIEDLRAAA 363 Query: 438 KVFLA-SGKKV--KVPTFLVPATQKV 506 V G++V + +VP + +V Sbjct: 364 GVVQKYEGQQVVKTIDAIIVPGSYRV 389
>LEU2_XANCP (P58949) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 94.7 bits (234), Expect = 2e-19 Identities = 72/222 (32%), Positives = 105/222 (47%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GS I +L+ME RMT+CNM IEAG + G+V Sbjct: 180 LPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRALSMEGRMTICNMSIEAGARVGMV 239 Query: 186 PADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DE T Y++G+ + + SDA A F + ++P V+ S Sbjct: 240 AVDEKTIAYVKGRPFAPKGADWDAAVALWRTLVSDADASFDTVVELRAEDIKPQVSWGTS 299 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P+ RAL + ++ +DRV+IGSCT + E Sbjct: 300 PEMVVAIDQQVPDPAAEQDPTKRDSIQRALKYMGLRANQPITEIHLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA V A G+K V +T K +L VPGSG Sbjct: 360 DLRAAAAV--AKGRK-------VASTIK-----QALVVPGSG 387
>LEU2_XANC8 (Q4UYG5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 94.7 bits (234), Expect = 2e-19 Identities = 72/222 (32%), Positives = 105/222 (47%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GS I +L+ME RMT+CNM IEAG + G+V Sbjct: 180 LPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRALSMEGRMTICNMSIEAGARVGMV 239 Query: 186 PADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DE T Y++G+ + + SDA A F + ++P V+ S Sbjct: 240 AVDEKTIAYVKGRPFAPKGADWDAAVALWRTLVSDADASFDTVVELRAEDIKPQVSWGTS 299 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P+ RAL + ++ +DRV+IGSCT + E Sbjct: 300 PEMVVAIDQQVPDPAAEQDPTKRDSIQRALKYMGLRANQPITEIHLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA V A G+K V +T K +L VPGSG Sbjct: 360 DLRAAAAV--AKGRK-------VASTIK-----QALVVPGSG 387
>LEU2_NOCFA (Q5YRY0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 94.7 bits (234), Expect = 2e-19 Identities = 59/210 (28%), Positives = 99/210 (47%), Gaps = 42/210 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++PP + +KD+IL +I +I G +E+ G + +++ME RMT+CNM IEAG + G+ Sbjct: 181 QLPPGVTSKDVILAVIAQIGTGGGQGYVLEYRGEAVRAMSMEARMTMCNMSIEAGARAGM 240 Query: 183 VPADETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T+++L+G+ ++ + +D A F ++ D S L P V Sbjct: 241 IAPDEVTYEFLKGRPHAPKGADWDAAVAAWDALRTDEGAVFDAEVHIDASSLSPFVTWGT 300 Query: 330 SPDNRA---------------LAREC----------------KDVKIDRVYIGSCTGGKT 416 +P A ARE ++V +D V++GSCT G+ Sbjct: 301 NPGQGAPLSATVPDPADFADETAREAAAKALRYMDLTPGTPLREVAVDTVFVGSCTNGRI 360 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKV 506 ED AAA++ V +VP + +V Sbjct: 361 EDLRAAAEILKGRRVAEGVRMLVVPGSMRV 390
>LEU2_NITOC (Q3J716) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 94.7 bits (234), Expect = 2e-19 Identities = 67/197 (34%), Positives = 94/197 (47%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + +KDLIL II I +G T ++EF G TI +L+ME RMTLCNM IEAG + G+ Sbjct: 174 KLAPGVYSKDLILAIIARIGTAGGTGYTIEFAGETIRALSMEGRMTLCNMAIEAGARAGL 233 Query: 183 VPADETTFKYLEGKTSV-----------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 V DETT YL+G+ ++ + SD A F D + L+P V+ Sbjct: 234 VAVDETTIDYLKGRPFAPSPHSWGQAVNAWQMLQSDPDASFDRVVTIDAAALKPQVSWGT 293 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 SP+ RAL +++ D ++IGSCT + Sbjct: 294 SPEMVASIDGRVPDPRQESDPTKRGGMERALEYMGLAANTPISEIRPDIIFIGSCTNARI 353 Query: 417 EDFIAAAKVFLASGKKV 467 ED AAKV +G KV Sbjct: 354 EDLREAAKV--VAGHKV 368
>LEU2_BACFR (Q64QP1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 94.7 bits (234), Expect = 2e-19 Identities = 63/204 (30%), Positives = 98/204 (48%), Gaps = 41/204 (20%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+ L ++ +++ SGAT +E+ G I SLTME R+TLCN+ IE G + G++ DE T Sbjct: 179 AKDIALYMMSKMTTSGATGYFVEYAGEAIRSLTMEGRLTLCNLSIEMGARGGMIAPDEVT 238 Query: 204 FKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVA---------- 320 F+Y++G+ +V+Y + + S+ A F + FD + +EP++ Sbjct: 239 FEYIKGRENAPQGEEWDQAVQYWKTLKSEDDAVFDKEVHFDAADIEPMITYGTNPGMGMG 298 Query: 321 -KPHSPDNRALARECK-------------------DVKIDRVYIGSCTGGKTEDFIAAAK 440 H P + K KID V++G+CT G+ EDF A A Sbjct: 299 ITQHIPTTDGMNETTKASFLKSLDYMGFQPGEALLGKKIDYVFLGACTNGRIEDFRAFAS 358 Query: 441 VFLASGKKVKVPTFLVPATQKVWM 512 + K V +LVP + WM Sbjct: 359 IVKGHQKAEHVIAWLVPGS---WM 379
>LEU2_BACFN (Q5LAB1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 464 Score = 94.7 bits (234), Expect = 2e-19 Identities = 63/204 (30%), Positives = 98/204 (48%), Gaps = 41/204 (20%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+ L ++ +++ SGAT +E+ G I SLTME R+TLCN+ IE G + G++ DE T Sbjct: 179 AKDIALYMMSKMTTSGATGYFVEYAGEAIRSLTMEGRLTLCNLSIEMGARGGMIAPDEVT 238 Query: 204 FKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVA---------- 320 F+Y++G+ +V+Y + + S+ A F + FD + +EP++ Sbjct: 239 FEYIKGRENAPQGEEWDQAVQYWKTLKSEDDAVFDKEVHFDAADIEPMITYGTNPGMGMG 298 Query: 321 -KPHSPDNRALARECK-------------------DVKIDRVYIGSCTGGKTEDFIAAAK 440 H P + K KID V++G+CT G+ EDF A A Sbjct: 299 ITQHIPTTDGMNETTKASFLKSLDYMGFQPGEALLGKKIDYVFLGACTNGRIEDFRAFAS 358 Query: 441 VFLASGKKVKVPTFLVPATQKVWM 512 + K V +LVP + WM Sbjct: 359 IVKGHQKAEHVIAWLVPGS---WM 379
>LEU2_CAMJE (Q9PLW1) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 470 Score = 94.4 bits (233), Expect = 2e-19 Identities = 66/211 (31%), Positives = 102/211 (48%), Gaps = 44/211 (20%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KDLIL +I + + T ++EF G I +L+ME RMTLCNM IE G K G++ DE TF Sbjct: 183 KDLILYLIAQYGTAKGTGYAIEFCGELIRNLSMEARMTLCNMAIEFGAKVGMIAPDEITF 242 Query: 207 KYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD----- 338 +Y++GK ++ + SD A++ + DVSK++P ++ +P Sbjct: 243 EYIKGKEFAPKGEEFQKYCEYWKSLRSDEGAKYDASITLDVSKIKPQISYGTNPSQVIGI 302 Query: 339 -----------NRALARECKD---------------VKIDRVYIGSCTGGKTEDFIAAAK 440 N++ + D VKID V+IGSCT G+ ED AA Sbjct: 303 DEKIPKISDFKNQSEQKSLLDALYYVNLEQDQVIEGVKIDIVFIGSCTNGRLEDLKIAAD 362 Query: 441 VFLASGKKV--KVPTFLVPATQKVWMDVYSL 527 + G+K+ V +VP + +V + +L Sbjct: 363 IL--KGRKIHKNVKALIVPGSMQVRKEAENL 391
>LEU2_CAMJR (Q5HS78) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 94.4 bits (233), Expect = 2e-19 Identities = 66/211 (31%), Positives = 102/211 (48%), Gaps = 44/211 (20%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KDLIL +I + + T ++EF G I +L+ME RMTLCNM IE G K G++ DE TF Sbjct: 181 KDLILYLIAQYGTAKGTGYAIEFCGELIRNLSMEARMTLCNMAIEFGAKVGMIAPDEITF 240 Query: 207 KYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD----- 338 +Y++GK ++ + SD A++ + DVSK++P ++ +P Sbjct: 241 EYIKGKEFAPKGEEFQKYCEYWKSLRSDEGAKYDASITLDVSKIKPQISYGTNPSQVIGI 300 Query: 339 -----------NRALARECKD---------------VKIDRVYIGSCTGGKTEDFIAAAK 440 N++ + D VKID V+IGSCT G+ ED AA Sbjct: 301 DEKIPKISDFKNQSEQKSLLDALYYVNLEQDQVIEGVKIDIVFIGSCTNGRLEDLKIAAD 360 Query: 441 VFLASGKKV--KVPTFLVPATQKVWMDVYSL 527 + G+K+ V +VP + +V + +L Sbjct: 361 IL--KGRKIHKNVKALIVPGSMQVRKEAENL 389
>LEU2_GEOKA (Q5KWJ5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 94.0 bits (232), Expect = 3e-19 Identities = 68/205 (33%), Positives = 93/205 (45%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL IIG V T +EF G I ++MEERMT+CNM IEAG + G++ DETT Sbjct: 180 AKDVILAIIGRYGVGVGTGYIIEFTGEAIRRMSMEERMTICNMSIEAGARAGLISPDETT 239 Query: 204 FKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVV----------- 317 F YL G K + + SD A++ D S + P+V Sbjct: 240 FAYLRGRKYAPKGEEFDKAVERWRALASDEGAKYDKTIEIDASTIAPMVTWGTNPAMSTS 299 Query: 318 ---AKPH------SPDNRALARECK-----------DVKIDRVYIGSCTGGKTEDFIAAA 437 PH + A+ R + D+ + V+IGSCT + D AAA Sbjct: 300 VDGVVPHPEQFESKTEQNAVRRALEYMGLKPGTPITDIPVQHVFIGSCTNSRLSDLRAAA 359 Query: 438 KVFLASGKKVK--VPTFLVPATQKV 506 + GKKV V +VP +Q+V Sbjct: 360 SI--VKGKKVAPGVRALVVPGSQQV 382
>LEU2_SHIFL (Q821C2) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 466 Score = 93.6 bits (231), Expect = 4e-19 Identities = 72/220 (32%), Positives = 99/220 (45%), Gaps = 42/220 (19%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG+ +G T +EF G I L+ME RMTLCNM IE G K +V Sbjct: 176 PGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAALVAP 235 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVV------- 317 DETTF Y++G+ ++ + +D A F + ++ P V Sbjct: 236 DETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPG 295 Query: 318 ------------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDF 425 A P RA A + +V ID+V+IGSCT + ED Sbjct: 296 QVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AAA++ A G+KV P Q +L VPGSG Sbjct: 356 RAAAEI--AKGRKV------APGVQ-------ALVVPGSG 380
>LEU2_MYCBO (Q7TXH6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 93.6 bits (231), Expect = 4e-19 Identities = 66/211 (31%), Positives = 101/211 (47%), Gaps = 44/211 (20%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I +I G +E+ GS IESL+ME RMT+CNM IEAG + G+V Sbjct: 181 LPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMV 240 Query: 186 PADETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DETT+ +L G+ V ++ + +D A F ++ D + L P V + Sbjct: 241 APDETTYAFLRGRPHAPTGAQWDTALVYWQRLRTDVGAVFDTEVYLDAASLSPFVTWGTN 300 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P +ALA +++ +D V++GSCT G+ E Sbjct: 301 PGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTAMREIAVDAVFVGSCTNGRIE 360 Query: 420 DFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 D A+V G+KV V +VP + +V Sbjct: 361 DLRVVAEVL--RGRKVADGVRMLIVPGSMRV 389
>LEU2_ACTTI (Q44427) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 485 Score = 93.6 bits (231), Expect = 4e-19 Identities = 68/212 (32%), Positives = 98/212 (46%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + AKDLIL +I + G +E+ G I L+ME RMT+CNM IE G K G+ Sbjct: 193 ELRPGVSAKDLILTLITQTGTGGGNGHIVEYRGEAIRKLSMEGRMTICNMSIEWGAKAGM 252 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF YL G+ ++ + +D A + ++ D SK+ P + Sbjct: 253 IAPDETTFDYLSGRKHARRGADWDAAVAYWKTLATDEGAEYDTEIILDASKISPFITWGT 312 Query: 330 SPDN------------------------RALA-------RECKDVKIDRVYIGSCTGGKT 416 +P RALA +DV +D V++GSCT G+ Sbjct: 313 NPGQGAALDGVVPDPQDFLDEVERGAAERALAYMGLTPGTPFRDVPVDVVFVGSCTNGRL 372 Query: 417 EDFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 ED AAA V G+KV V +VP + +V Sbjct: 373 EDLRAAADVI--RGRKVADGVRMMIVPGSYQV 402
>LEU2_GLOVI (Q7NFV7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 93.2 bits (230), Expect = 5e-19 Identities = 65/208 (31%), Positives = 97/208 (46%), Gaps = 43/208 (20%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD+IL II ++ V + EF G+T E++ MEERMT+CNM IE G + G + Sbjct: 179 PGVFAKDVILHIIRKLGVKAGVGYAYEFAGTTFEAMNMEERMTVCNMAIEGGARCGYINP 238 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP- 335 D T+ YL+G+ +E + SD A++ FD +++ P V +P Sbjct: 239 DAVTYAYLKGRDFAPQGADWERAVAWWENLRSDPDAQYDDTIHFDAAEIAPTVTWGITPG 298 Query: 336 -----------------DNRALAREC------------KDVKIDRVYIGSCTGGKTEDFI 428 ++R LA E K+D +IGSCT G+ D Sbjct: 299 QGIAVDEIVPRPEELPGEDRPLAEEAYRYMDLAPGVPIVGTKVDVCFIGSCTNGRLSDLR 358 Query: 429 AAAKVFLASGKKVK--VPTFLVPATQKV 506 AA LA G+ V V F+VP +++V Sbjct: 359 EAAN--LARGRHVAPGVKAFVVPGSERV 384
>LEU2_XANAC (P58948) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 479 Score = 93.2 bits (230), Expect = 5e-19 Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GS I +L+ME RMT+CNM IEAG + G+V Sbjct: 180 LPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRTLSMEGRMTICNMAIEAGARVGMV 239 Query: 186 PADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DE T Y+ G+ + + SD A F + ++P V+ S Sbjct: 240 AVDEKTIAYVRGRPFAPKGAHWDAAVALWSTLVSDPDAHFDTVVELRAEDIKPQVSWGTS 299 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P+ RAL + +++DRV+IGSCT + E Sbjct: 300 PEMVLAIDQHVPDPAIEQDPTKRDSIERALKYMGLKANQPITAIRLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA V A G+K V +T K +L VPGSG Sbjct: 360 DLRAAAAV--AKGRK-------VASTIK-----QALVVPGSG 387
>LEU2_PROMA (Q7VDT0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 93.2 bits (230), Expect = 5e-19 Identities = 66/210 (31%), Positives = 97/210 (46%), Gaps = 41/210 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKDLIL +I ++ V + EF G I+ L+MEERMT+CNM IE G + G + D+ Sbjct: 179 VFAKDLILHVIQKLGVKDGVGYAYEFAGPAIDGLSMEERMTICNMAIEGGARCGYINPDK 238 Query: 198 TTFKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVA-------- 320 TTF YL+G K + +E + S A + + RF+ S + P V Sbjct: 239 TTFNYLKGRPYSPKGKEWEKAILWWESLASSKSAIYDDEVRFNASLIAPTVTWGITPGQS 298 Query: 321 --------KPHSPD--NRALAREC------------KDVKIDRVYIGSCTGGKTEDFIAA 434 P S D ++ +A E + + ID +IGSCT G+ D A Sbjct: 299 IAIDASIPTPESLDKNDQQIALEAYKYMDLKPGSSIEGIPIDVCFIGSCTNGRLSDLEKA 358 Query: 435 AKVFLASGKKVKVPTFLVPATQKVWMDVYS 524 A++ V F+VP ++KV D S Sbjct: 359 AEIAKNRQVAKGVKAFVVPGSEKVAQDAES 388
>LEU2_PSYAR (Q4FRU7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 93.2 bits (230), Expect = 5e-19 Identities = 61/190 (32%), Positives = 95/190 (50%), Gaps = 42/190 (22%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 +KD++L II +I +G T ++EF G E ++ME RMT+CNM IEAG + G+V D+TT Sbjct: 186 SKDVVLAIIAKIGTAGGTGHAIEFAGQVFEDMSMEGRMTVCNMAIEAGARVGMVAVDDTT 245 Query: 204 FKYLEGKTSVEYEPVYSDAQA---RFYSD--------YRFDVSKLEPVVAKPHSPD---- 338 Y++G+ E + A+A FYSD D S++ P V+ SP+ Sbjct: 246 INYVKGRPYAPNESQWQQAEAYWRTFYSDDDAVFDSVVEIDGSQIAPQVSWGTSPEMVVD 305 Query: 339 --------NRAL-------------------ARECKDVKIDRVYIGSCTGGKTEDFIAAA 437 ++A+ ++ D+++DR++IGSCT + ED AA Sbjct: 306 VTQSVPTLDQAIDEAQEEGWLRAYTYMGLEAGQKITDIQLDRIFIGSCTNSRIEDLRDAA 365 Query: 438 KVFLASGKKV 467 V G+KV Sbjct: 366 AVI--KGRKV 373
>HACA_THET2 (Q9ZNE0) Probable homoaconitase large subunit (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 418 Score = 93.2 bits (230), Expect = 5e-19 Identities = 63/171 (36%), Positives = 95/171 (55%), Gaps = 4/171 (2%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEF-VGSTIESLTMEERMTLCNMVIEAGGKNG- 179 +P + AKD L+++ ++ GATY ++E + E+LT ERMTL N+ +EAG K G Sbjct: 165 LPKGVTAKDAALEMVRLLTAEGATYMAVEIHLLDGAEALTRGERMTLANLTVEAGAKAGL 224 Query: 180 VVPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARE 359 VVP+ E Y + +Y D AR+ + D+S L P V+ P DN + Sbjct: 225 VVPSGEILEMYRVP------DWLYPDPDARYAKEVEIDLSALTPRVSVPFYVDNVHEVAQ 278 Query: 360 CKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 K ++D+V+IG+CT G+ ED AAA+V G+KV V +VPA+ +V Sbjct: 279 VKGKRVDQVFIGTCTNGRIEDLRAAAEVL--RGRKVAPWVRLLVVPASSQV 327
>LEU2_CANMA (Q00464) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 770 Score = 93.2 bits (230), Expect = 5e-19 Identities = 67/223 (30%), Positives = 101/223 (45%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ + +KDL+L +IG I +G T +EF G IE L+ME RM++CNM IEAG + G+ Sbjct: 180 ELSEGITSKDLVLHVIGVIGTAGGTGCVIEFAGKAIEDLSMEARMSICNMAIEAGARAGM 239 Query: 183 VPADETTFKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE TF+Y++G K ++ +++D A+ + D + S + P + + Sbjct: 240 IKPDEKTFEYIKGRPLAPKGDEWEKALKYWKTLHTDDGAKLHYDIKIAASDIVPTITWGN 299 Query: 330 SPDN------------------------RALARECKD-------VKIDRVYIGSCTGGKT 416 SP + RAL + +K+ + +IGSCT + Sbjct: 300 SPQDALPITASVPDPANVSDPIKKSGMERALKYQGLTPNTPFVVIKMHKAFIGSCTNSRI 359 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED AAAKV K V LV VPGSG Sbjct: 360 EDLRAAAKVAKGHKKADNVKLVLV--------------VPGSG 388
>LEU2_CORDI (Q6NHL0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 480 Score = 92.8 bits (229), Expect = 6e-19 Identities = 61/210 (29%), Positives = 95/210 (45%), Gaps = 42/210 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + AKDLIL +I I G +E+ G IE L+ME RMT+CNM IEAG + G+ Sbjct: 187 ELQPGVTAKDLILAVIATIGTGGGQGHVIEYRGEAIEKLSMEARMTVCNMSIEAGARAGM 246 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF Y++G+ ++ + +D A F ++ D S + P + Sbjct: 247 IAPDETTFDYIKGREMAPTGQDWDDAVAYWKTLPTDEGAEFDTEITIDGSAITPFITWGT 306 Query: 330 SP------------------DNRALARE-------------CKDVKIDRVYIGSCTGGKT 416 +P DN +A E +D+ ID V++GSCT + Sbjct: 307 NPGQGLPLSSVVPSPEDFPGDNEKVAAEKALAYMGLTPGTPLRDIAIDTVFLGSCTNARM 366 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKV 506 +D AA + V +VP++ + Sbjct: 367 DDLRIAADILRGRSIADSVRMMVVPSSTMI 396
>LEU2_BUCUN (Q9EVI6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 443 Score = 92.4 bits (228), Expect = 8e-19 Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P ++ AKD+IL IIG++ S T +EF G I +++MEERMT+CNM IE G K+G+ Sbjct: 173 KIPRFVTAKDIILFIIGKLGSSSGTGHVIEFCGDVIRNMSMEERMTICNMAIEMGAKSGL 232 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE T+ YL+ K S++Y + + SD A + + ++S L P + Sbjct: 233 IAPDEITYSYLKNKIYSPSGLFWQKSLDYWKLLKSDHNAHYDKCFTVNISNLAPQITWGT 292 Query: 330 SPD---------------NRALARE-----CK-----------DVKIDRVYIGSCTGGKT 416 + D N + ++ C+ ++ ID+V+IGSCT + Sbjct: 293 NLDQVISIDEKIPDFNDVNSTIKKDSAKSACEYMGLKSNTYLTNISIDKVFIGSCTNARI 352 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +AA + +K+ V ++ VPGSG Sbjct: 353 EDLRSAAGIL---------------KNKKIAKHVQAIVVPGSG 380
>LEU21_DEIRA (Q9RTY9) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 434 Score = 92.0 bits (227), Expect = 1e-18 Identities = 62/171 (36%), Positives = 94/171 (54%), Gaps = 3/171 (1%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNG- 179 ++ P + AKD+ L++I + GATY+S+E + T ERMTL N+ +EAG K G Sbjct: 181 DLRPGVTAKDVALEMIRVLGADGATYQSVEIHAG--DRFTRGERMTLANLCVEAGAKAGL 238 Query: 180 VVPADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARE 359 VVP E Y G + VY D A + + D+S L P ++ P DN E Sbjct: 239 VVPGGEILTDY--GYDVPAW--VYPDEGAAYAREVEIDLSALHPRMSAPSEVDNVHDVAE 294 Query: 360 CKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPT--FLVPATQKV 506 + +K+D+V+IG+CT G+ ED AAA+V G++V T ++PA+ +V Sbjct: 295 LRGLKVDQVFIGTCTNGRIEDLHAAAEVL--RGRRVDPTTRLLVIPASSQV 343
>LEU2_PROMP (Q7V336) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 91.7 bits (226), Expect = 1e-18 Identities = 61/204 (29%), Positives = 93/204 (45%), Gaps = 41/204 (20%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKDL+L II ++ V + EF G I L+MEERMT+CNM IE G + G + DE Sbjct: 179 IYAKDLVLHIINQLGVKAGVGYAYEFAGPAISELSMEERMTICNMSIEGGARCGYINPDE 238 Query: 198 TTFKYLEGK----------TSVEYEPVYSDAQARFYSD-YRFDVSKLEPVVA-------- 320 TF Y++ K +V++ + Y D ++ D SK+EP + Sbjct: 239 KTFSYMKDKLCSPQNENWEKAVKWWKSLESSDNCVYDDVFKLDASKVEPTITWGITPGQS 298 Query: 321 ----------KPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIAA 434 P+++ +A E K+ ID +IGSCT G+ D A Sbjct: 299 IGVNQKIPSLNQIHPNDQFIAEEAYEYMSFKPGQSIKNTPIDVCFIGSCTNGRISDLRVA 358 Query: 435 AKVFLASGKKVKVPTFLVPATQKV 506 A+V + + F+VP ++KV Sbjct: 359 AQVLEHNKVAKNIKAFVVPGSEKV 382
>LEU2_SYNPX (Q7U9J4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 91.7 bits (226), Expect = 1e-18 Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 43/204 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKDLIL +I + V G + EF G +E+L+MEERMTLCNM IE G + G V D+ T Sbjct: 181 AKDLILHVIRTLGVKGGVGFAYEFAGPAVEALSMEERMTLCNMAIEGGARCGYVNPDQVT 240 Query: 204 FKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVA---------- 320 F YL G+ + + SD A + FD + + P V Sbjct: 241 FDYLSGRAGAPSGAAWDRAVSWWRGLASDPDAVVDDEVVFDAASIAPTVTWGITPGQGLG 300 Query: 321 --------KPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIAAAK 440 + P R +A E V +D +IGSCT G+ D AAA Sbjct: 301 IDECIPQLEQLEPGERPIAEEAYRYMDLQPGTAIAGVPVDVCFIGSCTNGRLSDLRAAAA 360 Query: 441 VFLASGKKVK--VPTFLVPATQKV 506 V A G+ V + F+VP +++V Sbjct: 361 V--ARGRHVADGIKAFVVPGSEQV 382
>LEU2_XANC5 (Q3BPJ6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 482 Score = 91.7 bits (226), Expect = 1e-18 Identities = 70/222 (31%), Positives = 103/222 (46%), Gaps = 42/222 (18%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD++L +IG+I +G ++EF GS I + +ME RMT+CNM IEAG + G+V Sbjct: 180 LPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRAASMEGRMTICNMAIEAGARVGMV 239 Query: 186 PADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DE T Y++G+ + + SD A F + ++P V+ S Sbjct: 240 AVDEKTIAYVKGRPFAPKGAHWDAAVALWSTLVSDPDAHFDTVVELRAEDIKPQVSWGTS 299 Query: 333 PD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKTE 419 P+ RAL + +++DRV+IGSCT + E Sbjct: 300 PEMVLAIDQHVPDPAAEQDPTKRDSIERALKYMGLTANQPITAIRLDRVFIGSCTNSRIE 359 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 D AAA V A G+K V +T K +L VPGSG Sbjct: 360 DLRAAAAV--AKGRK-------VASTIK-----QALVVPGSG 387
>LEU21_BRAJA (Q89X98) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 477 Score = 91.7 bits (226), Expect = 1e-18 Identities = 65/214 (30%), Positives = 100/214 (46%), Gaps = 44/214 (20%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 MP + AKDLIL +IG + +G T ++E+ GS I + +E R+T+CN+ +E G K G++ Sbjct: 184 MPFGVTAKDLILALIGHVGAAGGTGYAVEYAGSAIRGMPIEGRLTICNLSVELGAKMGLI 243 Query: 186 PADETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 D+TTF Y+ G+ + + SD+ A F + DV + P + S Sbjct: 244 APDQTTFDYVRGRPYAPQGEMWERAVTAWRTLRSDSDAMFDREVTIDVGTIIPQITWGTS 303 Query: 333 P-----------DNRALARECK--------------------DVKIDRVYIGSCTGGKTE 419 P D R +A + K+D V+IGSCT + Sbjct: 304 PEHVLGVDGRVPDPRDIADPARRGAIEIALDYMGLKPGAPIAGTKVDWVFIGSCTNSRLS 363 Query: 420 DFIAAAKVFLASGKKVK--VPTFLVPATQKVWMD 515 D AAA+V A G+KV V ++VP ++ V D Sbjct: 364 DLRAAAEV--ARGRKVAPGVRAWVVPGSETVKRD 395
>LEU2_STRT2 (Q5M406) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 91.3 bits (225), Expect = 2e-18 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 35/198 (17%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + +KD IL +I + V+ +E+ G I+ LTMEERMT+CNM IE G K G++ D+ Sbjct: 178 IYSKDYILALIAKYGVACGVGYVVEYRGEAIDRLTMEERMTICNMSIEFGSKMGIMNPDQ 237 Query: 198 TTFKYLEGKTSV---------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP----- 335 TT+ Y+ G+ V +++ + SD A + R DVS+L P+V +P Sbjct: 238 TTYDYMRGRECVPEDFDAAVADWKTLVSDDDAEYDKVIRMDVSELAPMVTWGTNPSMGVD 297 Query: 336 ------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASG 458 D RA ++ +D+ + ++IGSCT + D AA++ G Sbjct: 298 FDTPFPEVRDMNDERAYHYMGLRPGQKAEDINLGYIFIGSCTNARLSDLQLAARI--VKG 355 Query: 459 KKV--KVPTFLVPATQKV 506 KK+ + +VP ++ V Sbjct: 356 KKISPNLTAIVVPGSRPV 373
>LEU2_STRT1 (Q5LZF4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 91.3 bits (225), Expect = 2e-18 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 35/198 (17%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + +KD IL +I + V+ +E+ G I+ LTMEERMT+CNM IE G K G++ D+ Sbjct: 178 IYSKDYILALIAKYGVACGVGYVVEYRGEAIDRLTMEERMTICNMSIEFGSKMGIMNPDQ 237 Query: 198 TTFKYLEGKTSV---------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP----- 335 TT+ Y+ G+ V +++ + SD A + R DVS+L P+V +P Sbjct: 238 TTYDYMRGRECVPEDFDAAVADWKTLVSDDDAEYDKVIRMDVSELAPMVTWGTNPSMGVD 297 Query: 336 ------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASG 458 D RA ++ +D+ + ++IGSCT + D AA++ G Sbjct: 298 FDTPFPEVRDMNDERAYHYMGLRPGQKAEDINLGYIFIGSCTNARLSDLQLAARI--VKG 355 Query: 459 KKV--KVPTFLVPATQKV 506 KK+ + +VP ++ V Sbjct: 356 KKISPNLTAIVVPGSRPV 373
>LEU2_MYCPA (Q73VI7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 91.3 bits (225), Expect = 2e-18 Identities = 64/212 (30%), Positives = 100/212 (47%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + AKD+IL +I +I G +E+ GS IESL+ME RMT+CNM IEAG + G+ Sbjct: 183 ELPAGVTAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTVCNMSIEAGARAGM 242 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D+TT+++L + ++ + +D A F ++ D + L P V Sbjct: 243 IAPDDTTYEFLRDRPHAPKGAQWDAAMRYWQQLRTDPGAVFDTEVYLDAASLSPFVTWGT 302 Query: 330 SPD------------------------NRALA-------RECKDVKIDRVYIGSCTGGKT 416 +P +ALA +D+ +D V++GSCT G+ Sbjct: 303 NPGQGVPLAAAVPDPELMTDDAERQAAEKALAYMDLRPGTPMRDIAVDAVFVGSCTNGRI 362 Query: 417 EDFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 ED A V G+KV V +VP + +V Sbjct: 363 EDLRVVADVL--RGRKVAPGVRMLVVPGSMRV 392
>LEU2_PROMM (Q7V4U5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 478 Score = 90.9 bits (224), Expect = 2e-18 Identities = 65/204 (31%), Positives = 92/204 (45%), Gaps = 43/204 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKDLIL +I + V + EF G I+ L+MEERMTLCNM IE G + G V D T Sbjct: 181 AKDLILHVIRSLGVKAGVGYAYEFAGPAIDVLSMEERMTLCNMAIEGGARCGYVNPDGVT 240 Query: 204 FKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVV----------- 317 F YL+G + + + SD A F + FD + + P+V Sbjct: 241 FDYLQGRFYAPTGEALHRAVAWWRSLASDPNAVFDDEVTFDAASIAPMVTWGITPGQGIA 300 Query: 318 -------AKPHSPDNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIAAAK 440 A P R ++ E + V +D +IGSCT G+ D AAA Sbjct: 301 VDESVPTADSLEPSERPISEEACRYMDLEPGMAIEGVPVDVCFIGSCTNGRLSDLKAAAA 360 Query: 441 VFLASGKKVK--VPTFLVPATQKV 506 + A G+ V + F+VP +++V Sbjct: 361 I--AKGRHVAQGIKAFVVPGSEQV 382
>LEU2_COREF (Q8FPR3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 90.9 bits (224), Expect = 2e-18 Identities = 63/212 (29%), Positives = 97/212 (45%), Gaps = 42/212 (19%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + +KDLIL II +I G +E+ G I L+M+ RMT+CNM IEAG + G+ Sbjct: 189 ELQPGVSSKDLILAIIAKIGTGGGQGYVLEYRGEAIRKLSMDARMTICNMSIEAGARAGM 248 Query: 183 VPADETTFKYLEGK----TSVEYEPVY-------SDAQARFYSDYRFDVSKLEPVVAKPH 329 + DETTF+Y++G+ T +++ +D A F D S L P V Sbjct: 249 IAPDETTFEYVKGREMAPTGADWDEAVAYWKTLPTDEGAEFDKVVEIDGSSLTPFVTWGT 308 Query: 330 SP------------------DNRALARE-------------CKDVKIDRVYIGSCTGGKT 416 +P DN A E +++KID V++GSCT + Sbjct: 309 NPGQGLPLSESVPDPEDFTNDNDKAAAEKALQYMDLTPGTPLREIKIDTVFLGSCTNARI 368 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWM 512 ED AA++ G+K+ ++ W+ Sbjct: 369 EDLEIAAEIL--KGRKIADDIRMMVVPSSTWV 398
>LEU2_MYCLE (O33123) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 476 Score = 90.1 bits (222), Expect = 4e-18 Identities = 63/209 (30%), Positives = 97/209 (46%), Gaps = 42/209 (20%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P + AKD+IL +I +I G +E+ GS IES++ME RMT+CNM IEAG + G+V Sbjct: 184 LPAGVTAKDIILALIAKIGTGGGQGYVLEYRGSVIESMSMEGRMTICNMSIEAGARAGMV 243 Query: 186 PADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHS 332 DETT+++L + +V Y + + +D A F ++ D + L P V + Sbjct: 244 APDETTYEFLRDRPHAPTGKQWDAAVAYWQQLRTDDDAVFDTEVYLDATSLSPFVTWGTN 303 Query: 333 PDN------------------------RALA-------RECKDVKIDRVYIGSCTGGKTE 419 P +ALA +D+ +D V++GSCT G+ E Sbjct: 304 PGQGVPLAASVPDPELMIDDVARQAAEKALAYMDLRPGTPMRDIAVDAVFVGSCTNGRIE 363 Query: 420 DFIAAAKVFLASGKKVKVPTFLVPATQKV 506 D A V V +VP + +V Sbjct: 364 DLRLVADVLRGHKVADGVRMLIVPGSMRV 392
>LEU2_BUCPS (P58945) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 465 Score = 90.1 bits (222), Expect = 4e-18 Identities = 63/207 (30%), Positives = 92/207 (44%), Gaps = 42/207 (20%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD+IL II ++S SG +EF GS I L+ME RMT+CNM IE G K+G++ Sbjct: 176 PMVFAKDIILSIIRKLSTSGGIGYVIEFSGSVISQLSMESRMTICNMSIEMGAKSGLIAP 235 Query: 192 DETTFKYLEGKT----------SVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD 338 D T+ YL+ K+ ++ Y + SD A F ++S L P + PD Sbjct: 236 DIITYNYLKNKSYSPKNKYWNNAINYWNTLKSDKNAFFDKKISINISNLAPQITWGTKPD 295 Query: 339 NRALARE-------------------------------CKDVKIDRVYIGSCTGGKTEDF 425 E ++ +D+V+IGSCT +TED Sbjct: 296 QVISIDEPIPNIDSLKMFLNKNQLKNPLLYMGLKPGEYLNNLVVDKVFIGSCTNSRTEDL 355 Query: 426 IAAAKVFLASGKKVKVPTFLVPATQKV 506 AAA + + V +VP + V Sbjct: 356 RAAANIVQNTHVAKNVHAIVVPGSGMV 382
>LEU2_BUCBP (P59519) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 90.1 bits (222), Expect = 4e-18 Identities = 69/218 (31%), Positives = 99/218 (45%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD+IL +I ++ VS +EF G + L+ME RMTLCNM IE G K+G++ D Sbjct: 178 ITAKDIILFVIKQLGVSRGLGYVIEFSGEIVSKLSMESRMTLCNMSIEMGAKSGIIAPDS 237 Query: 198 TTFKYL-------EGKT---SVEY-EPVYSDAQARFYSDYRFDVSKLEPVV--------- 317 TF YL +GK +++Y + + SD A F ++ D+S L P V Sbjct: 238 VTFSYLCNRKYVPKGKNWNLAIDYWKTLKSDTGAIFDQEFNIDISNLSPQVTWGTNPSQV 297 Query: 318 -----AKPH-----SPDNRALAR------------ECKDVKIDRVYIGSCTGGKTEDFIA 431 PH P R A DV I +V+IGSCT + ED A Sbjct: 298 ISINDTIPHLESYSDPIERRSAELSLLYMGLEPGMSLIDVNIQKVFIGSCTNSRIEDLRA 357 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AK+ + ++V V+++ VPGSG Sbjct: 358 VAKIVM---------------NKRVCNSVHAIIVPGSG 380
>LEU2_BUCUD (Q9EVE0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 444 Score = 89.7 bits (221), Expect = 5e-18 Identities = 66/223 (29%), Positives = 107/223 (47%), Gaps = 42/223 (18%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P ++ AKD+IL +IG++ S T +EF G+ I++++MEERMT+CNM IE K+G+ Sbjct: 174 KIPKFVTAKDIILFVIGQLGSSSGTGYVIEFCGNIIKNMSMEERMTVCNMAIEMXAKSGL 233 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + T+KYL+ K S++Y + + SD A F D+S L P + Sbjct: 234 IAPXXITYKYLKDKIYSPSGLFWEKSLDYWKCLKSDKNAYFDKCITVDISNLAPQITWGT 293 Query: 330 SPD---------------NRALARE-----CK-----------DVKIDRVYIGSCTGGKT 416 +PD N + ++ CK ++ ID+V+IGS T + Sbjct: 294 NPDQVISIDEKIPDYNNINSEVKKDSAKSACKYMGLKSNTYLTNISIDKVFIGSXTNARI 353 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 ED +AAK+ +K+ V ++ VPGSG Sbjct: 354 EDLRSAAKIL---------------QNRKIAKHVKAIVVPGSG 381
>LEU2_AZOSE (Q5P1J8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 469 Score = 89.7 bits (221), Expect = 5e-18 Identities = 69/216 (31%), Positives = 98/216 (45%), Gaps = 42/216 (19%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+ L IIG + +G T ++EF GS I +L+ME RMT+CNM IEAG + G+V D+TT Sbjct: 182 AKDIALAIIGRLGTAGGTGYAIEFGGSAIRALSMEGRMTICNMAIEAGARAGLVAVDQTT 241 Query: 204 FKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 YL K +V Y + +D A+F D ++++P V SP+ Sbjct: 242 IDYLRDKPLAPKGQAWEQAVAYWRTLKTDDGAKFDKIVELDAAQIQPQVTWGTSPEMVET 301 Query: 339 --------------------NRALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAA 437 RAL ++ +D+V+IGSCT + ED AA Sbjct: 302 VSGRVPDPAGIGDPVRREGIERALKYMGLAPNTPISEIPVDQVFIGSCTNSRIEDLREAA 361 Query: 438 KVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 V K P+ ++V L VPGSG Sbjct: 362 SVAKGRSK--------APSVKRV------LVVPGSG 383
>LEU2_STRGN (Q9AIM3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 456 Score = 89.0 bits (219), Expect = 9e-18 Identities = 57/199 (28%), Positives = 91/199 (45%), Gaps = 33/199 (16%) Frame = +3 Query: 9 PPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVP 188 P + +KD IL +I V+ +E+ G IE LTMEERMT+CNM IE G K G++ Sbjct: 171 PKGVYSKDFILALIARYGVAAGVGHVVEYAGDAIEHLTMEERMTICNMSIEFGSKMGIMN 230 Query: 189 ADETTFKYLEGKTS---------VEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP-- 335 D+ T+ Y++G+ +++ + SD A + DVS+L P+V +P Sbjct: 231 PDQKTYDYVQGRPGAPKDFEAAVADWKTLVSDPDAVYDKVIEIDVSQLAPMVTWGTNPSM 290 Query: 336 ---------------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFL 449 D RA ++ +D+ + ++IGSCT + D AAK Sbjct: 291 GVEFGAAFPEIRDMNDERAYNYMDLSPGKKAEDIDLGYIFIGSCTNARLSDLQLAAKFVA 350 Query: 450 ASGKKVKVPTFLVPATQKV 506 + +VP ++ V Sbjct: 351 GKHIAPNLTAIVVPGSRPV 369
>LEU2_GLUOX (Q5FUG3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 475 Score = 89.0 bits (219), Expect = 9e-18 Identities = 66/204 (32%), Positives = 89/204 (43%), Gaps = 42/204 (20%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + AKD++L IIG I +G T +EF GS I L M RMTLCNM IEAG + G+V Sbjct: 181 PGVTAKDILLAIIGRIGTAGGTGHVIEFAGSAIRDLDMAGRMTLCNMSIEAGARAGLVAP 240 Query: 192 DETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD 338 DETTF Y++G+ + + SD A F ++ ++ P V SP Sbjct: 241 DETTFAYVKGRPFAPKGEAFEQACDYWRSLASDDGAYFDTEVTLAAEEIIPSVTWGTSPQ 300 Query: 339 N------------------------RAL-------ARECKDVKIDRVYIGSCTGGKTEDF 425 N RAL ++ +D V+IGSCT + ED Sbjct: 301 NVLPIDGSVPSPSDEPDPARAAQIQRALDYMGLEAGQKIAGTPVDVVFIGSCTNSRLEDL 360 Query: 426 IAAAKVFLASGKKVKVPTFLVPAT 497 AAA V V +VP + Sbjct: 361 RAAADVVRGRHVAEGVRAMIVPGS 384
>LEU21_MANSM (Q65VS0) 3-isopropylmalate dehydratase large subunit 1 (EC| 4.2.1.33) (Isopropylmalate isomerase 1) (Alpha-IPM isomerase 1) (IPMI 1) Length = 475 Score = 89.0 bits (219), Expect = 9e-18 Identities = 59/212 (27%), Positives = 95/212 (44%), Gaps = 44/212 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P AKD+I+ ++ +I GAT ++EF G I+ L++E RMT+CNM +E G + Sbjct: 179 KLPFGTTAKDVIMALVAKIGADGATNYAIEFCGEVIDELSVEGRMTICNMAVECGARGAF 238 Query: 183 VPADETTFKYLEGK-----------TSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + DE ++Y++G E+ + SD A F + D S LEP V Sbjct: 239 MAPDEKVYEYIKGTPRAPKGEMWDLAIAEWRKLKSDNDAVFDKEIHMDCSDLEPFVTWGI 298 Query: 330 SPDNRAL-------------------------------ARECKDVKIDRVYIGSCTGGKT 416 SPD + + +++KI +IGSCT G+ Sbjct: 299 SPDQADVISGEVPDPNLLPEGQKRKDYQAALEYMGLEPGMKFEEIKISHAFIGSCTNGRI 358 Query: 417 EDFIAAAKVFLASGKKVK--VPTFLVPATQKV 506 ED AKV G+K+ V ++P + +V Sbjct: 359 EDLREVAKVL--KGRKIAQGVRGMIIPGSTQV 388
>LEU22_PYRFU (Q8U0C0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 380 Score = 89.0 bits (219), Expect = 9e-18 Identities = 52/165 (31%), Positives = 86/165 (52%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 Y++A D+IL ++ + YR++EF +++ER+TL N V+EA K G++ + Sbjct: 157 YVMATDVILHLLSLLKDYDMNYRAVEFFNVPF---SLDERLTLTNFVVEANAKTGIIGEE 213 Query: 195 ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVK 374 T Y++ + +++ L P+VAKPH+P N E + K Sbjct: 214 YTGDGYVK--------------------ELEIELNSLNPLVAKPHNPANVVPVEEVEGTK 253 Query: 375 IDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 ID+V+IGSCT G+ E AA++ G+KV V T + PA+ V+ Sbjct: 254 IDQVFIGSCTNGRFEQISKAAEIL--EGEKVAVRTIVGPASMNVY 296
>LEU2_CHRVO (Q7NUB6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 471 Score = 88.6 bits (218), Expect = 1e-17 Identities = 69/218 (31%), Positives = 96/218 (44%), Gaps = 42/218 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + AKD+ L IIG+I +G T ++EF G I L+ME RMTLCNM IE G ++G+V D+ Sbjct: 180 ITAKDVALAIIGKIGTAGGTGYAIEFGGEAIRGLSMEGRMTLCNMAIEGGARSGMVAVDD 239 Query: 198 TTFKYLEGKT----------SVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD-- 338 T +Y++G+ +V Y ++SD A F D + ++P V SP+ Sbjct: 240 KTIEYVKGRPFAPKGEQWNQAVAYWNTLHSDDGAHFDQVVALDAADIQPQVTWGTSPEMV 299 Query: 339 ----------------------NRALA-------RECKDVKIDRVYIGSCTGGKTEDFIA 431 RALA + + +D V+IGSCT + ED Sbjct: 300 AEVGGKVPNPANESDPVKKAGIERALAYMGLEADTPIEQIPVDVVFIGSCTNSRIEDLRE 359 Query: 432 AAKVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 AA V K V LV VPGSG Sbjct: 360 AAAVAKGRSKAGNVKQVLV--------------VPGSG 383
>LEU2_CORGL (P58946) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 481 Score = 87.4 bits (215), Expect = 3e-17 Identities = 61/203 (30%), Positives = 92/203 (45%), Gaps = 46/203 (22%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + +KDLIL II +I G +E+ G I ++M+ RMT+CNM IEAG + G+ Sbjct: 189 ELQPGVSSKDLILAIIAKIGTGGGQGYVLEYRGEAIRKMSMDARMTMCNMSIEAGARAGM 248 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D+TTF Y+EG+ ++ + +D A F D S L P + Sbjct: 249 IAPDQTTFDYVEGREMAPKGADWDEAVAYWKTLPTDEGATFDKVVEIDGSALTPFITWGT 308 Query: 330 SP------------------DNRALARE-------------CKDVKIDRVYIGSCTGGKT 416 +P DN A E +D+KID V++GSCT + Sbjct: 309 NPGQGLPLGESVPSPEDFTNDNDKAAAEKALQYMDLVPGTPLRDIKIDTVFLGSCTNARI 368 Query: 417 EDFIAAAKVF----LASGKKVKV 473 ED AA + +A G ++ V Sbjct: 369 EDLQIAADILKGHKIADGMRMMV 391
>LEU2_STRMU (Q8DTG4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 461 Score = 87.4 bits (215), Expect = 3e-17 Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 33/194 (17%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 +KD IL +I + V+ +E++G +++L+MEERMT+CNM IE G K G++ D+ T Sbjct: 180 SKDYILALIAKYGVALGVGYVVEYIGDAVDALSMEERMTICNMSIEFGSKMGIMNPDQKT 239 Query: 204 FKYLEGKTSV---------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP------- 335 F YL+ K V +++ + SD A + DVS+L P+V +P Sbjct: 240 FDYLKNKACVPEDFETAVADWKTLVSDEDAHYDKVIELDVSQLAPMVTWGTNPSMGVAFG 299 Query: 336 ----------DNRAL-------ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKK 464 D RA + +D+++ V++GSCT + D AAK Sbjct: 300 QAFPDIRDMNDKRAYDYMDMKPGQTAEDIELGYVFLGSCTNARLSDLKVAAKYVAGKHIA 359 Query: 465 VKVPTFLVPATQKV 506 + +VP ++ V Sbjct: 360 PNLTAIVVPGSRPV 373
>LEU2_DECAR (Q47HR4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 87.0 bits (214), Expect = 3e-17 Identities = 72/216 (33%), Positives = 93/216 (43%), Gaps = 42/216 (19%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+ L IIG I +G T ++EF GS I L+ME RMTLCNM IE G + G V D+TT Sbjct: 181 AKDVALAIIGTIGTAGGTGYAIEFGGSAIRGLSMEGRMTLCNMAIEGGARLGFVAVDDTT 240 Query: 204 FKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 YL+G+ +V Y ++SDA A+F + P V SP+ Sbjct: 241 INYLKGRPFSPTGETWDRAVAYWRTLHSDAGAQFDRVVTLRAEDIRPQVTWGTSPEMVVS 300 Query: 339 --------------------NRALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAA 437 RAL + ID+V+IGSCT + ED AA Sbjct: 301 VDAVVPDPAKEADPVKREGMERALQYMGLNPNTPINQIAIDKVFIGSCTNSRIEDLREAA 360 Query: 438 KVFLASGKKVKVPTFLVPATQKVWMDVYSLPVPGSG 545 V G+ V L +L VPGSG Sbjct: 361 SVL--KGRHVAANVKL------------ALAVPGSG 382
>LEU2_OCEIH (Q8EN69) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 468 Score = 86.7 bits (213), Expect = 4e-17 Identities = 63/199 (31%), Positives = 87/199 (43%), Gaps = 41/199 (20%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKDLIL II + V T ME+ G +I ++MEERMT+CNM IEAG + G++ D+TT Sbjct: 181 AKDLILAIIAKFGVQFGTGYVMEYTGESIRKMSMEERMTICNMSIEAGARAGLISPDQTT 240 Query: 204 FKYLEGKTSVEYEPVYSDAQARFY-----SDYRFD------------------------- 293 YL G+ V Y A + D +D Sbjct: 241 VDYLRGREMVPKGEAYDTLAAEWLQLATDEDAVYDDTVTIHANEIEPQVTWGTNPGMCVP 300 Query: 294 VSKLEPVVAKPHSPDNRALARE---------CKDVKIDRVYIGSCTGGKTEDFIAAAKVF 446 +S P + K PD A E +++D V+IGSCT + D AA + Sbjct: 301 ISSSTPSIEKASYPDEVERALEYMGLTENQLMTSIEVDHVFIGSCTNSRLSDLKKAAAI- 359 Query: 447 LASGKKVK--VPTFLVPAT 497 GKKVK + +VP + Sbjct: 360 -VKGKKVKAGIRAMVVPGS 377
>LEU2_SCHPO (O14289) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 758 Score = 86.7 bits (213), Expect = 4e-17 Identities = 63/197 (31%), Positives = 95/197 (48%), Gaps = 42/197 (21%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + +KDLIL IIG I +G T +EF G IE L+ME RM++CNM IEAG + G+ Sbjct: 185 KLPEGIASKDLILHIIGVIGTAGGTGSVIEFCGEAIEGLSMEARMSMCNMSIEAGARAGM 244 Query: 183 VPADETTFKYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPH 329 + D TTF+Y++ + +V Y + + SD A++ + + + + P V Sbjct: 245 IAPDATTFEYVKNRPLAPKGDDWEQAVAYWKTLRSDENAKYDIEVEINAADVLPTVTWGT 304 Query: 330 SP-----------------DNRALARECKDVK--------------IDRVYIGSCTGGKT 416 SP DN A + ++ ID+V+IGSCT + Sbjct: 305 SPQDVIPINGNIPDPAHVKDNVRAASIQRSLEYMGLKPNTSIVSYPIDKVFIGSCTNSRI 364 Query: 417 EDFIAAAKVFLASGKKV 467 ED AA V G+KV Sbjct: 365 EDLRLAAAV--VKGRKV 379
>LEU2_THET8 (Q9ZND5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 85.5 bits (210), Expect = 1e-16 Identities = 64/208 (30%), Positives = 91/208 (43%), Gaps = 41/208 (19%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 + P + AKD+IL II + V G + E+ GS +E++ ME RMTLCNM IE G + G V Sbjct: 174 LAPGVYAKDVILHIIRHLGVKGGLGYAYEYGGSAVEAMDMESRMTLCNMSIEGGARIGYV 233 Query: 186 PADETTFKYLEGKTSVEYEPVYSDAQARF----------YSDY-RFDVSKLEPVVAKPHS 332 DETTF+YLEG+ V + +A+ R+ Y D F ++ P V + Sbjct: 234 NPDETTFQYLEGRPYVPKGSEWEEAKRRWLAWRSDPDASYDDVVTFRAEEIAPTVTWGIT 293 Query: 333 P------------------DNRALAREC------------KDVKIDRVYIGSCTGGKTED 422 P + R +A E K V I +IGSCT + D Sbjct: 294 PGQAIPIDGRIPLLEELPEEERPVAEEALAYMGFRPGQPIKGVPIQVAFIGSCTNARLSD 353 Query: 423 FIAAAKVFLASGKKVKVPTFLVPATQKV 506 A+ K V +VP ++ V Sbjct: 354 LREVARYLKGHKVKKGVRALVVPGSEWV 381
>LEU2_THET2 (Q72JB3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 85.5 bits (210), Expect = 1e-16 Identities = 64/208 (30%), Positives = 91/208 (43%), Gaps = 41/208 (19%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 + P + AKD+IL II + V G + E+ GS +E++ ME RMTLCNM IE G + G V Sbjct: 174 LAPGVYAKDVILHIIRHLGVKGGLGYAYEYGGSAVEAMDMESRMTLCNMSIEGGARIGYV 233 Query: 186 PADETTFKYLEGKTSVEYEPVYSDAQARF----------YSDY-RFDVSKLEPVVAKPHS 332 DETTF+YLEG+ V + +A+ R+ Y D F ++ P V + Sbjct: 234 NPDETTFQYLEGRPYVPKGSEWEEAKRRWLAWRSDPDASYDDVVTFRAEEIAPTVTWGIT 293 Query: 333 P------------------DNRALAREC------------KDVKIDRVYIGSCTGGKTED 422 P + R +A E K V I +IGSCT + D Sbjct: 294 PGQAIPIDGRIPLLEELPEEERPVAEEALAYMGFRPGQPIKGVPIQVAFIGSCTNARLSD 353 Query: 423 FIAAAKVFLASGKKVKVPTFLVPATQKV 506 A+ K V +VP ++ V Sbjct: 354 LREVARYLKGHKVKKGVRALVVPGSEWV 381
>LEU2_BACSU (P80858) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Superoxide-inducible protein 10) (SOI10) Length = 472 Score = 85.5 bits (210), Expect = 1e-16 Identities = 61/205 (29%), Positives = 97/205 (47%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL +IG+ V T +E+ G ++TM+ERMT+CNM IEAG + G++ DE T Sbjct: 180 AKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMTVCNMSIEAGARAGLIAPDEVT 239 Query: 204 FKYLEG-----------KTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP----- 335 F+Y + K E++ + +D A + D +K+ P+V +P Sbjct: 240 FEYCKNRKYTPKGEEFDKAVEEWKALRTDPGAVYDKSIVLDGNKISPMVTWGINPGMVLP 299 Query: 336 --------------DNRALA------------RECKDVKIDRVYIGSCTGGKTEDFIAAA 437 D++ A ++ +D+K++ V+IGSCT + D AA Sbjct: 300 VDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKIEDIKVEHVFIGSCTNSRMTDLRQAA 359 Query: 438 KVFLASGKKV--KVPTFLVPATQKV 506 + GKKV V +VP +Q V Sbjct: 360 D--MIKGKKVADSVRAIVVPGSQSV 382
>LEU2_RHINI (P55811) 3-isopropylmalate dehydratase (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 750 Score = 84.0 bits (206), Expect = 3e-16 Identities = 66/205 (32%), Positives = 96/205 (46%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 +KD+ L +IG I +G T +EF G ESL+ME RM++CNM IEAG + G++ D+ T Sbjct: 186 SKDIALHVIGVIGTAGGTGCVIEFCGEANESLSMESRMSICNMSIEAGARAGMIAPDDIT 245 Query: 204 FKYLEGKTSVEYEPVYSDAQA-----RFYSDYRFDV------SKLEPVVAKPHSPDN--- 341 F+YL K + A A +F +D ++D+ S + P V SP + Sbjct: 246 FEYLCNKPLASKGEEWDRAVAYWKTLKFDADAQYDITVDIKASDIAPTVTWGTSPQDVAP 305 Query: 342 ---------------RALARE-------------CKDVKIDRVYIGSCTGGKTEDFIAAA 437 R LA + + VKID+V+IGSCT + ED AA Sbjct: 306 ITGKTPDLDSIADPLRRLAVQRALDYIGIASNTPLEGVKIDKVFIGSCTNSRIEDLGPAA 365 Query: 438 KVFLASGKKVK--VPTFLVPATQKV 506 + GK+V V +VP + V Sbjct: 366 AI--VKGKRVADWVDAMVVPGSALV 388
>LEU2_ACIAD (Q6FEW0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 477 Score = 83.2 bits (204), Expect = 5e-16 Identities = 57/189 (30%), Positives = 91/189 (48%), Gaps = 42/189 (22%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD++L IIG+I +G T ++EF G +++E RMT+CNM IEAG + G+V D+ T Sbjct: 192 KDVVLAIIGKIGTAGGTGYAIEFGGQVFRDMSIEGRMTVCNMAIEAGARVGMVAVDDKTI 251 Query: 207 KYLEGK----------TSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD----- 338 +Y++ + +V Y ++SD A F + +++EP V+ SP+ Sbjct: 252 EYVQSRHYAPKGEQWDQAVAYWNTLHSDDDAVFDEVVVLNGAEIEPQVSWGTSPEMVIPV 311 Query: 339 --------------------------NRALARECKDVKIDRVYIGSCTGGKTEDFIAAAK 440 + D+++DRV+IGSCT + ED AAA+ Sbjct: 312 SQAVPTLEQAKDDVQRNDWTRAYQYMGLTAGQALADIQLDRVFIGSCTNSRIEDIRAAAE 371 Query: 441 VFLASGKKV 467 V G+KV Sbjct: 372 V--VKGRKV 378
>LEU2_HALMA (Q5V518) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 82.8 bits (203), Expect = 6e-16 Identities = 60/203 (29%), Positives = 87/203 (42%), Gaps = 42/203 (20%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL+II + G E+ G TIE+L ME RM++CNM IE G + G V DETT Sbjct: 181 AKDIILEIIRRLGTEGGVGYVYEYAGETIENLDMEGRMSICNMSIEGGARAGYVNPDETT 240 Query: 204 FKYLEGKTSVE------------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP---- 335 +++LE + +E + SD A + D +L+PVV +P Sbjct: 241 YEWLEETDYFQEHPEKFEELKPYWESIRSDEDAEYDDVVEIDAGELDPVVTWGTTPGQGI 300 Query: 336 --------------DNRALAREC------------KDVKIDRVYIGSCTGGKTEDFIAAA 437 D AR + ID ++GSCT + D AA Sbjct: 301 GIDDPIPEPEDLADDKVDTARRAQKHMRVEPGETMEGYDIDVAFLGSCTNARLPDLRRAA 360 Query: 438 KVFLASGKKVKVPTFLVPATQKV 506 ++ V F+VP +Q+V Sbjct: 361 RIVKGREVADDVRAFVVPGSQRV 383
>LEU2_NATPD (Q3IRQ4) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 474 Score = 82.0 bits (201), Expect = 1e-15 Identities = 61/210 (29%), Positives = 90/210 (42%), Gaps = 42/210 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ + AKD+IL II + G E+ G IE+L ME RM++CNM IE G + G Sbjct: 174 ELGEGVTAKDIILTIIRRLGTDGGVGYVYEYAGEAIENLGMEGRMSICNMSIEGGARAGY 233 Query: 183 VPADETTFKYLEGKTSVE------------YEPVYSDAQARFYSDYRFDVSKLEPVVAKP 326 V DETT+++L + +E V SD A + D S++EPVV Sbjct: 234 VNPDETTYEWLRETDAFADDPERFEELKPYWESVRSDPDAEYDDVVTIDGSEIEPVVTWG 293 Query: 327 HSP------------------DNRALARECKD------------VKIDRVYIGSCTGGKT 416 +P D + AR +D ID ++GSCT + Sbjct: 294 TTPGQGIGITEEIPAPEDLPADKQDTARRAQDHMGVEPGETMAGYNIDVAFLGSCTNARL 353 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKV 506 D +AA++ V +VP +Q+V Sbjct: 354 PDLRSAAEIIKGREVHDSVRAMVVPGSQRV 383
>LEU2_HALVO (Q7ZAG7) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 473 Score = 81.3 bits (199), Expect = 2e-15 Identities = 62/210 (29%), Positives = 91/210 (43%), Gaps = 42/210 (20%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+ P + AKD+IL+II + G E+ G IE L ME RM++CNM IE G + G Sbjct: 174 ELGPGVEAKDVILEIIRRLGTEGGVGYVYEYAGEAIEDLDMEGRMSICNMSIEGGARAGY 233 Query: 183 VPADETTFKYLEGKTSVE------------YEPVYSDAQARFYSDYRFDVSKLEPVVAKP 326 V DETT+++L+ + +E + SD A + D S+LEPVV Sbjct: 234 VNPDETTYEWLKETEYFQENPERFDELKPYWESIRSDEDAEYDDVVTIDGSELEPVVTWG 293 Query: 327 HSP---------------------DNRALARECKDV---------KIDRVYIGSCTGGKT 416 +P + +A+E V +ID ++GSCT + Sbjct: 294 TTPGQGVGITQPIPAPEDLPEEKQETARMAQEHMGVTPGETMEGYEIDVAFLGSCTNARL 353 Query: 417 EDFIAAAKVFLASGKKVKVPTFLVPATQKV 506 D AA V V +VP +Q+V Sbjct: 354 PDLRRAAGVVKGRQVADSVRAMVVPGSQRV 383
>LEU2_LACLA (Q02142) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 460 Score = 80.5 bits (197), Expect = 3e-15 Identities = 53/176 (30%), Positives = 85/176 (48%), Gaps = 34/176 (19%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + +KD IL +I + V ++E+ G I L+MEERMT+CNM IE G K G++ DE Sbjct: 178 IYSKDFILALIAKYGVDAGVGYAVEYSGDAISDLSMEERMTICNMSIEFGAKIGLMNPDE 237 Query: 198 TTFKYLEGKTSV---------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD---- 338 T+ Y++G+ ++E + SD+ A++ DVS+L+P+V +P Sbjct: 238 KTYDYVKGREHAPKNFDEAVSKWEKLVSDSDAQYDKILSLDVSQLKPMVTWGTNPGMGLE 297 Query: 339 ------------NRALARECKDVK---------IDRVYIGSCTGGKTEDFIAAAKV 443 N A + D+K + ++IGSCT + D AAK+ Sbjct: 298 FGEKFPEINNDLNYERAYQYMDLKPGQTASAIDLGYIFIGSCTNARLGDLEEAAKI 353
>LEU2_BACLD (Q65GJ0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 472 Score = 79.7 bits (195), Expect = 5e-15 Identities = 60/205 (29%), Positives = 97/205 (47%), Gaps = 44/205 (21%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL IIG+ V +E+ G +++M+ERMT+CNM IEAG + G++ DETT Sbjct: 180 AKDVILAIIGKYGVKFGAGYVIEYTGEVFRNMSMDERMTVCNMSIEAGARAGLIAPDETT 239 Query: 204 FKYLEGKTSV-----------EYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSP----- 335 F+Y++ K E++ + +D A + D S + P+V +P Sbjct: 240 FEYVKTKKYAPKGEDFEKAVEEWKNLKTDPGAVYDRTIVMDGSAISPMVTWGINPGMVLP 299 Query: 336 --------------DNRALA------------RECKDVKIDRVYIGSCTGGKTEDFIAAA 437 D++ A ++ +D+ I+ V+IGSCT + D AA Sbjct: 300 VDETIPGPEAFLQEDDKKEAQRAYEYMGLEPYKKIEDITIEHVFIGSCTNSRMTDLRQAA 359 Query: 438 KVFLASGKKVK--VPTFLVPATQKV 506 + + G+KV V +VP +Q V Sbjct: 360 E--MIKGQKVADGVRAIVVPGSQSV 382
>LEU22_METKA (Q8TW29) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 402 Score = 79.3 bits (194), Expect = 7e-15 Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 1/162 (0%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKDL L ++GE+ A Y +E+ G E +++ +RM LCN+ EAG K+ VP E Sbjct: 171 AKDLALTVVGELGAGYADYAVLEYTGLP-ERMSLGDRMCLCNLATEAGAKSAYVPPKEGP 229 Query: 204 FKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVKIDR 383 + G E D S++EPVV+ PH D+ + + V++ R Sbjct: 230 EELRPGDADEVIE---------------LDASEVEPVVSVPHRVDDVRPVGDVQGVEVTR 274 Query: 384 VYIGSCTGGKTEDFIAAAKVF-LASGKKVKVPTFLVPATQKV 506 V++GSCT G+ D ++ G V +VPA+++V Sbjct: 275 VFVGSCTNGRYRDVRVFTEILEELDGPHPDVRIVVVPASRRV 316
>LEU2_ZYMMO (Q5NRC5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 484 Score = 79.0 bits (193), Expect = 9e-15 Identities = 58/189 (30%), Positives = 90/189 (47%), Gaps = 42/189 (22%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++ P + AKDLIL II + +G T ++E+ G I +L++EER+T+ NM IEAG + G+ Sbjct: 182 KLSPDVSAKDLILHIIHSLGTAGGTGYAIEYTGEAIRNLSIEERLTVSNMSIEAGARTGL 241 Query: 183 VPADETTFKYLEGKTSVE-----------YEPVYSDAQARF----------------YSD 281 + ADE TF YL G+ ++ + +D A + + Sbjct: 242 IAADEKTFAYLFGRPMAPKGADWEKAVQWWKSLATDKGAVYDKTVIIKAEDVQPSVTWGT 301 Query: 282 YRFDVSKLEPVVAKPHS---PDNRALAR------------ECKDVKIDRVYIGSCTGGKT 416 DV + VV P S P +A AR + + + ++ V+IGSCT + Sbjct: 302 SPEDVVPITGVVPDPASFADPAKQAAARRSLEYMGLEPGQKMEGLAVENVFIGSCTNSRI 361 Query: 417 EDFIAAAKV 443 ED AAA V Sbjct: 362 EDLRAAASV 370
>LYS4_EMENI (Q92412) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 775 Score = 79.0 bits (193), Expect = 9e-15 Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 30/183 (16%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGS--TIESLTMEERMTLCNMVIEAGGKNG 179 +PP + KD+I+ + G + ++EF GS T+ SL+++ R+T+ NM E G +G Sbjct: 233 LPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEWGALSG 292 Query: 180 VVPADETTFKYLEGKTSVE--------------------------YEPVYSDAQARFYSD 281 + P D +L GK + P+ +D A++ + Sbjct: 293 LFPIDSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGAKYAKE 352 Query: 282 YRFDVSKLEPVVAKPHSPDNRALAR--ECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLAS 455 D+S L P V+ P+S + E +++K+D+ Y+ SCT + D AAAKVF + Sbjct: 353 LFLDLSSLSPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAKVFKEA 412 Query: 456 GKK 464 +K Sbjct: 413 AEK 415
>LEU2_PYRKO (Q5JFV6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 380 Score = 77.8 bits (190), Expect = 2e-14 Identities = 49/164 (29%), Positives = 81/164 (49%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 ++A D ++ II + Y+++EF + +ER+TL N +EA K G++ + Sbjct: 158 VMAADAMIHIITALRDFEMNYKAIEFFNVPF---SFDERLTLTNFSVEANAKTGIIGEEY 214 Query: 198 TTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVKI 377 + Y+ + D+S L P+VAKPH P N E + KI Sbjct: 215 SGDGYV--------------------LELGIDLSSLPPMVAKPHHPSNGVPVEEVEGTKI 254 Query: 378 DRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 D+V+IGSCT G+ E AA++ +G++V V T + PA+ V+ Sbjct: 255 DQVFIGSCTNGRFEQIERAAEIL--AGEEVAVRTIIGPASANVY 296
>LEU22_PYRAB (Q9V1J0) 3-isopropylmalate dehydratase large subunit 2 (EC| 4.2.1.33) (Isopropylmalate isomerase 2) (Alpha-IPM isomerase 2) (IPMI 2) Length = 380 Score = 76.3 bits (186), Expect = 6e-14 Identities = 50/166 (30%), Positives = 82/166 (49%), Gaps = 1/166 (0%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 Y++A D+++ +I + +Y ++EF + +ER+TL N +EA K ++ Sbjct: 157 YIMASDVMIHLITSLKDREMSYNAIEFFNVPF---SFDERLTLTNFSVEANAKTAII--- 210 Query: 195 ETTFKYLEGKTSVEYEPV-YSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDV 371 EYE YSD + ++ L P+VAKP SP N + + Sbjct: 211 -----------GEEYEGGGYSD-------EITIELDSLPPMVAKPFSPANGVSVEDVEGT 252 Query: 372 KIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 KID+V+IGSCT G+ E AA++ G++V V T + PA+ V+ Sbjct: 253 KIDQVFIGSCTNGRFEQIKRAAEIL--DGEQVNVRTLVAPASINVY 296
>LEU2_RALEU (Q44023) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (Fragment) Length = 267 Score = 74.7 bits (182), Expect = 2e-13 Identities = 57/183 (31%), Positives = 83/183 (45%), Gaps = 44/183 (24%) Frame = +3 Query: 90 EFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTFKYLEGK----TSVEYEP---- 245 EF GS + SL +E R+TLCN+ +E +G+V D+T F+YL G+ ++EP Sbjct: 1 EFGGSAVRSLPVEARLTLCNLAVEFSAFSGIVAPDDTVFEYLAGRPYAPAGAQWEPALWH 60 Query: 246 ---VYSDAQARFYSDYRFDVSKLEPVVAKPHSPDN------------------------R 344 +YSDA A F + D +L P+V SP + R Sbjct: 61 WRSLYSDADAVFDRELSVDCRQLAPMVTWGTSPQHGVAVDGAVPNPAMAIDADTRQAMER 120 Query: 345 ALA-------RECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVK--VPTFLVPAT 497 AL+ + D+ ID +IGSCT + D +AA V +G+KV V VP + Sbjct: 121 ALSYMDLRPGQRMADIAIDAAFIGSCTNSRLSDLRSAAGVL--AGRKVAPGVTAICVPVS 178 Query: 498 QKV 506 V Sbjct: 179 SAV 181
>LEU2_PYRHO (O59391) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 380 Score = 74.3 bits (181), Expect = 2e-13 Identities = 47/163 (28%), Positives = 81/163 (49%) Frame = +3 Query: 21 LAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADET 200 +A D+++++I + Y+++EF T +ER+TL N +EA K ++ + Sbjct: 159 MAADVMIRLITSLRNYDMNYKALEFFNVPF---TADERLTLTNFSVEANAKTALIGEEYD 215 Query: 201 TFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALARECKDVKID 380 Y++ + F++S L P+VAKP SP N + + KID Sbjct: 216 GRNYIK--------------------EISFELSSLGPMVAKPFSPANGVEVEKVEGTKID 255 Query: 381 RVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVW 509 +V+IGSCT G+ E AA++ G++V V T + PA+ V+ Sbjct: 256 QVFIGSCTNGRFEHIKRAAEIL--KGEEVAVRTIIGPASVNVY 296
>LEU2_MYCSM (Q938C9) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)| (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) Length = 422 Score = 72.8 bits (177), Expect = 7e-13 Identities = 47/175 (26%), Positives = 80/175 (45%), Gaps = 1/175 (0%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 MP + KD+ L I + AT ++E+ G + S+ + +R T+ E Sbjct: 164 MPAGVSGKDVFLYIAD--AFGDATNSNLEYGGPGLASIPLNDRRTIATQGAEISADFSTF 221 Query: 186 PADETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD-NRALAREC 362 D+ ++ + YEP ++D A + + D+S L P VA+P + N E Sbjct: 222 AYDDVLAEHFDDLGITSYEPAHADPDAAYAAVREIDLSALAPYVARPGTVSRNGVSVDEV 281 Query: 363 KDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPTFLVPATQKVWMDVYSL 527 + KID+ +IGSC G+ +D AA++ V + PA+Q+V+ D L Sbjct: 282 EPRKIDQAFIGSCANGQLDDLRIAAEILRGRRVAPGVRLIVTPASQQVYRDAMRL 336
>ACON_CAEEL (P34455) Probable aconitate hydratase, mitochondrial precursor (EC| 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 777 Score = 68.2 bits (165), Expect = 2e-11 Identities = 55/182 (30%), Positives = 84/182 (46%), Gaps = 21/182 (11%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 AKD+IL++ ++V G T +E+ G ++S++ T+CNM E G V P +E+ Sbjct: 241 AKDVILKVADILTVKGGTGAIVEYFGPGVDSISATGMGTICNMGAEIGATTSVFPYNESM 300 Query: 204 FKYLE--GKTSVEYEP------VYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRA---- 347 +KYLE G+ + E + +D A + ++ L P V P +PD + Sbjct: 301 YKYLEATGRKEIAEEARKYKDLLTADDGANYDQIIEINLDTLTPHVNGPFTPDLASSIDK 360 Query: 348 LARECK------DVKIDRVYIGSCTGGKTEDFIAA---AKVFLASGKKVKVPTFLVPATQ 500 L K DVK+ IGSCT ED A AK L G K K + P ++ Sbjct: 361 LGENAKKNGWPLDVKVS--LIGSCTNSSYEDMTRAASIAKQALDKGLKAKTIFTITPGSE 418 Query: 501 KV 506 +V Sbjct: 419 QV 420
>ACON_YEAST (P19414) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 21/181 (11%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G +V G T + +E+ G +++ + T+CNM E G V P +++ Sbjct: 241 KDIILKLAGITTVKGGTGKIVEYFGDGVDTFSATGMGTICNMGAEIGATTSVFPFNKSMI 300 Query: 207 KYLE----GKTSVEYEPVY------SDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAR 356 +YLE GK + ++ +Y +D A + D++ LEP + P +PD Sbjct: 301 EYLEATGRGKIA-DFAKLYHKDLLSADKDAEYDEVVEIDLNTLEPYINGPFTPDLATPVS 359 Query: 357 ECKDVKIDRVY--------IGSCTGGKTEDFIAAAKVF---LASGKKVKVPTFLVPATQK 503 + K+V + + IGSCT ED +A + A G K K + P +++ Sbjct: 360 KMKEVAVANNWPLDVRVGLIGSCTNSSYEDMSRSASIVKDAAAHGLKSKTIFTVTPGSEQ 419 Query: 504 V 506 + Sbjct: 420 I 420
>ACON2_YEAST (P39533) Putative aconitase in PRP21-UBP12 intergenic region (EC| 4.2.1.3) Length = 789 Score = 65.1 bits (157), Expect = 1e-10 Identities = 45/182 (24%), Positives = 81/182 (44%), Gaps = 22/182 (12%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+I ++ G ++V G T +E+ G + +L+ T+CNM E G P E Sbjct: 242 KDVITKLAGLLTVRGGTGYIVEYFGEGVSTLSCTGMATICNMGAEIGATTSTFPYQEAHK 301 Query: 207 KYLEGKTSVE-----------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD----- 338 +YL+ E + + +D A++ D+S +EP V P +PD Sbjct: 302 RYLQATNRAEVAEAADVALNKFNFLRADKDAQYDKVIEIDLSAIEPHVNGPFTPDLSTPI 361 Query: 339 NRALARECKD---VKIDRVYIGSCTGGKTEDF---IAAAKVFLASGKKVKVPTFLVPATQ 500 ++ + K+ K+ IGSCT +D + K +G K ++P F+ P ++ Sbjct: 362 SQYAEKSLKENWPQKVSAGLIGSCTNSSYQDMSRVVDLVKQASKAGLKPRIPFFVTPGSE 421 Query: 501 KV 506 ++ Sbjct: 422 QI 423
>LYS4_CANGA (Q6FM51) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 689 Score = 64.7 bits (156), Expect = 2e-10 Identities = 51/175 (29%), Positives = 80/175 (45%), Gaps = 26/175 (14%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD---- 194 KD+I+ + G + ++EF G I+ L ++ R+T+ NM E G +G+ P D Sbjct: 192 KDIIVALCGVFNKDQVLNHAIEFTGDAIKHLPVDFRLTIANMTTEWGALSGLFPVDDTLI 251 Query: 195 ------------------ETTFKYLEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVA 320 ETT K LE K V +D+ A + D+S L V+ Sbjct: 252 NWYKNRLNIVGPNHPRINETTIKNLEDKAKV----FKADSDAVYAKKLVIDLSTLTHYVS 307 Query: 321 KPH----SPDNRALARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKV 473 P+ S + LAR+ ++KI++ Y+ SCT + D +AAKV +G KV Sbjct: 308 GPNSVKVSNTVQDLARD--NIKINKAYLVSCTNARLSDLESAAKVVCPTGDLSKV 360
>ACON_SCHPO (O13966) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 64.3 bits (155), Expect = 2e-10 Identities = 48/179 (26%), Positives = 80/179 (44%), Gaps = 19/179 (10%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G ++V G T +E+ G +ESL+ T+CNM E G + P + Sbjct: 241 KDVILKVAGILTVKGGTGAIVEYFGPGVESLSCTGMGTICNMGAEIGATTSIFPFNPRMS 300 Query: 207 KYLEGKT-------SVEYEPVY-SDAQARFYSDYRFDVSKLEPVVAKPHSPD-------- 338 +YL + E+ P+ +D A + D++ LEP + P +PD Sbjct: 301 EYLRATNRSAIADYAEEFAPIIAADENAHYDQIIEIDLNTLEPHLNGPFTPDLATPISKF 360 Query: 339 NRALARECKDVKIDRVYIGSCTGGKTEDFIAAAKV---FLASGKKVKVPTFLVPATQKV 506 A+ + ++ IGSCT ED AA + + G K K + P +++V Sbjct: 361 KEAVKKNDWPQELKVGLIGSCTNSSYEDMSRAASICQQAIDKGIKTKSLFTITPGSEQV 419
>ACON_MOUSE (Q99KI0) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 63.2 bits (152), Expect = 5e-10 Identities = 48/179 (26%), Positives = 81/179 (45%), Gaps = 19/179 (10%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G ++V G T +E+ G ++S++ T+CNM E G V P + Sbjct: 245 KDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMK 304 Query: 207 KYLE--GKTSVE------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD-------- 338 KYL G+T + + + D ++ ++++L+P + P +PD Sbjct: 305 KYLSKTGRTDIANLAEEFKDHLVPDPGCQYDQVIEINLNELKPHINGPFTPDLAHPVADV 364 Query: 339 NRALARECKDVKIDRVYIGSCTGGKTEDF---IAAAKVFLASGKKVKVPTFLVPATQKV 506 +E + I IGSCT ED A AK LA G K K + P ++++ Sbjct: 365 GTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQI 423
>ACON_HUMAN (Q99798) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 62.8 bits (151), Expect = 7e-10 Identities = 50/180 (27%), Positives = 80/180 (44%), Gaps = 20/180 (11%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G ++V G T +E+ G ++S++ T+CNM E G V P + Sbjct: 245 KDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMK 304 Query: 207 KYLEGKTSVE---------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD------- 338 KYL KT E + + D + ++S+L+P + P +PD Sbjct: 305 KYL-SKTGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAE 363 Query: 339 -NRALARECKDVKIDRVYIGSCTGGKTEDF---IAAAKVFLASGKKVKVPTFLVPATQKV 506 + +E + I IGSCT ED A AK LA G K K + P ++++ Sbjct: 364 VGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQI 423
>LYS4_YEAST (P49367) Homoaconitase, mitochondrial precursor (EC 4.2.1.36)| (Homoaconitate hydratase) Length = 693 Score = 62.8 bits (151), Expect = 7e-10 Identities = 45/182 (24%), Positives = 80/182 (43%), Gaps = 25/182 (13%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P + KD+I+ + G + ++EF G ++ +L ++ R+T+ NM E G +G+ Sbjct: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246 Query: 183 VPADET-----------------------TFKYLEGKTSVEYEPVYSDAQARFYSDYRFD 293 P D+T T + LE K + +D A + D Sbjct: 247 FPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIP----KADKDAHYAKKLIID 302 Query: 294 VSKLEPVVAKPHS--PDNRALARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKV 467 ++ L V+ P+S N +D+KI++ Y+ SCT + D +AA V +G Sbjct: 303 LATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN 362 Query: 468 KV 473 KV Sbjct: 363 KV 364
>ACON_PIG (P16276) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 781 Score = 62.0 bits (149), Expect = 1e-09 Identities = 48/179 (26%), Positives = 79/179 (44%), Gaps = 19/179 (10%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G ++V G T +E+ G ++S++ T+CNM E G V P + Sbjct: 245 KDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMK 304 Query: 207 KYLE--GKTSVE------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD-------- 338 KYL G+ + + + D + ++S+L+P + P +PD Sbjct: 305 KYLSKTGRADIANLADEFKDHLVPDPGCHYDQVIEINLSELKPHINGPFTPDLAHPVAEV 364 Query: 339 NRALARECKDVKIDRVYIGSCTGGKTEDF---IAAAKVFLASGKKVKVPTFLVPATQKV 506 +E + I IGSCT ED A AK LA G K K + P ++++ Sbjct: 365 GSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQI 423
>ACON_RAT (Q9ER34) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 61.2 bits (147), Expect = 2e-09 Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 19/179 (10%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G ++V G T +E+ G ++S++ T+CNM E G V P + Sbjct: 245 KDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMK 304 Query: 207 KYLE--GKTSVE------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD-------- 338 KYL G+ + + + D ++ ++++L+P + P +PD Sbjct: 305 KYLSKTGRADIANLAEEFKDHLVPDPGCQYDQVIEINLNELKPHINGPFTPDLAHPVADV 364 Query: 339 NRALARECKDVKIDRVYIGSCTGGKTEDF---IAAAKVFLASGKKVKVPTFLVPATQKV 506 +E + I IGSCT ED A AK LA G K K + P ++++ Sbjct: 365 GTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQI 423
>ACON_CORDI (Q6NH63) Aconitate hydratase (EC 4.2.1.3)| Length = 934 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 14/136 (10%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + A D++L I + G + +EF G+ ++S+ + R T+ NM E G + Sbjct: 250 EIPAGVTATDVVLTITEMLREHGVVQKFVEFYGNGVKSIPLANRATIGNMSPEFGSTCAI 309 Query: 183 VPADETTFKYL----EGKTSVEYEPVYSDAQARF---------YSDY-RFDVSKLEPVVA 320 P DE T KY+ + V Y+ AQ + YS+Y D+S + P +A Sbjct: 310 FPIDEETVKYMHLTGRSEEQVALVEAYAKAQGMWLEQDAPEAEYSEYLELDLSTVVPSIA 369 Query: 321 KPHSPDNRALARECKD 368 P P +R L E K+ Sbjct: 370 GPKRPQDRILLTEAKE 385
>ACON_BOVIN (P20004) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 60.8 bits (146), Expect = 3e-09 Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 19/179 (10%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G ++V G T +E+ G ++S++ T+CNM E G V P + Sbjct: 245 KDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMK 304 Query: 207 KYLE--GKTSVE------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPD-------- 338 KYL G+ + + + D+ + ++S+L+P + P +PD Sbjct: 305 KYLSKTGRADIANLADEFKDHLVPDSGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEV 364 Query: 339 NRALARECKDVKIDRVYIGSCTGGKTEDF---IAAAKVFLASGKKVKVPTFLVPATQKV 506 +E + I IGSCT ED A AK LA G + K + P ++++ Sbjct: 365 GSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLQCKSQFTITPGSEQI 423
>ACON_GRAVE (P49609) Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3)| (Citrate hydro-lyase) (Aconitase) Length = 779 Score = 60.1 bits (144), Expect = 4e-09 Identities = 48/179 (26%), Positives = 82/179 (45%), Gaps = 19/179 (10%) Frame = +3 Query: 27 KDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETTF 206 KD+IL++ G ++V G T +E+ G ++SL+ T+CNM E G + P + Sbjct: 243 KDVILKVAGILTVKGGTGAIVEYFGEGVDSLSCTGMGTICNMGAEIGATTSMFPYNSRMG 302 Query: 207 KYLE--GKTSVE------YEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDNRALAREC 362 YL+ G+ + E + +D A + ++S+LEP + P +PD + Sbjct: 303 DYLKATGRDGIASLADSFSEQLRADENAVYDQLIEINLSELEPHINGPFTPDLAHPLSKF 362 Query: 363 KD--------VKIDRVYIGSCTGGKTEDFIAAAKVF---LASGKKVKVPTFLVPATQKV 506 K+ ++ IGSCT ED +A V L+ G K K + P +++V Sbjct: 363 KEEVEKNGWPAELTVGLIGSCTNSSYEDMARSASVVKQALSHGVKSKSIFNITPGSEQV 421
>ACON_COREF (Q8FTA8) Aconitate hydratase (EC 4.2.1.3)| Length = 937 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 14/136 (10%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + A D++L I + G + +EF G+ ++S+ + R T+ NM E G + Sbjct: 250 EIPVGVTATDVVLTITEMLRDHGVVQKFVEFYGNGVKSVPLANRATIGNMSPEFGSTCAM 309 Query: 183 VPADETTFKYL----EGKTSVEYEPVYSDAQARF---------YSDY-RFDVSKLEPVVA 320 P DE T KYL + + Y+ AQ + YS+Y D+S + P +A Sbjct: 310 FPIDEETIKYLRLTGRPEEQIALVEAYAKAQGMWLEQDAPEAEYSEYLELDLSTVVPSIA 369 Query: 321 KPHSPDNRALARECKD 368 P P +R L E K+ Sbjct: 370 GPKRPQDRILLSEAKE 385
>ACON_CORGL (Q8NQ98) Aconitate hydratase (EC 4.2.1.3)| Length = 939 Score = 58.5 bits (140), Expect = 1e-08 Identities = 41/136 (30%), Positives = 64/136 (47%), Gaps = 14/136 (10%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + A D++L I + G + +EF GS ++++ + R T+ NM E G + Sbjct: 250 EIPVGVTATDVVLTITEMLRDHGVVQKFVEFYGSGVKAVPLANRATIGNMSPEFGSTCAM 309 Query: 183 VPADETTFKYL----EGKTSVEYEPVYSDAQARF---------YSDY-RFDVSKLEPVVA 320 P DE T KYL + V Y+ AQ + YS+Y D+S + P +A Sbjct: 310 FPIDEETTKYLRLTGRPEEQVALVEAYAKAQGMWLDEDTVEAEYSEYLELDLSTVVPSIA 369 Query: 321 KPHSPDNRALARECKD 368 P P +R L E K+ Sbjct: 370 GPKRPQDRILLSEAKE 385
>ACON_CORJK (Q4JVM4) Aconitate hydratase (EC 4.2.1.3)| Length = 936 Score = 57.0 bits (136), Expect = 4e-08 Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 13/134 (9%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P + A D++L I + G + +EF G + L + R T+ NM E G + Sbjct: 250 EIPTGVTATDVVLTITDMLRQHGVVGKFVEFYGKGVGELPLANRATIGNMSPEFGSTAAM 309 Query: 183 VPADETTFKYLE----GKTSVEYEPVYSDAQARF--------YSDY-RFDVSKLEPVVAK 323 P DE T KYLE + ++E Y+ AQ + YS+Y D+S + P +A Sbjct: 310 FPIDEETVKYLELTGRDQETLERVEAYAKAQGMWLDPEKEVEYSEYLELDLSTVVPSIAG 369 Query: 324 PHSPDNRALARECK 365 P P +R + K Sbjct: 370 PKRPQDRIELNDSK 383
>ACOC_CUCMA (P49608) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate| hydro-lyase) (Aconitase) Length = 898 Score = 55.8 bits (133), Expect = 8e-08 Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 19/133 (14%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 A DL+L + + G + +EF G +E L++ +R T+ NM E G G P D T Sbjct: 261 ATDLVLTVTQMLRKHGVVGKFVEFYGDGMEELSLADRATIANMSPEYGATMGFFPVDHVT 320 Query: 204 FKYLE------------------GKTSVEYEPVYSDAQARFYSDY-RFDVSKLEPVVAKP 326 +YL+ K V+Y+ Q + YS Y + D++ +EP ++ P Sbjct: 321 LQYLKLTGRSDETVSMIEAYLRANKMFVDYK---EPQQEKVYSSYLQLDLTDVEPCISGP 377 Query: 327 HSPDNRALARECK 365 P +R +E K Sbjct: 378 KRPHDRVPLKEMK 390
>ACON_LEGPH (P37032) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) (Major iron-containing protein) (MICP) (IP210) Length = 891 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 14/123 (11%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + A DL+L + + G + +EF G + L + +R T+ NM E G G P D+ Sbjct: 264 ITATDLVLTVTQMLRKKGVVGKFVEFYGPGLNDLPLADRATISNMAPEYGATCGFFPVDK 323 Query: 198 TTFKYLE----GKTSVEYEPVYSDAQARFY----------SDYRFDVSKLEPVVAKPHSP 335 T KYLE K ++ Y+ AQ +Y D+ +EP +A P P Sbjct: 324 ETIKYLELTGRDKHTIALVEAYAKAQGMWYDKDNEEPVFTDSLHLDLGSVEPSLAGPKRP 383 Query: 336 DNR 344 ++ Sbjct: 384 QDK 386
>ACON1_ECOLI (P25516) Aconitate hydratase 1 (EC 4.2.1.3) (Citrate hydro-lyase 1)| (Aconitase 1) Length = 890 Score = 50.8 bits (120), Expect = 3e-06 Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 13/122 (10%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + A DL+L + + G + +EF G ++SL + +R T+ NM E G G P D Sbjct: 261 ITATDLVLTVTQMLRKHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDA 320 Query: 198 TTFKY--LEGKTSVEYEPVYSDAQAR-----------FYSDYRFDVSKLEPVVAKPHSPD 338 T Y L G++ + E V A+A+ F S D++ +E +A P P Sbjct: 321 VTLDYMRLSGRSEDQVELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQ 380 Query: 339 NR 344 +R Sbjct: 381 DR 382
>ACOC_CUCMC (Q42669) Aconitase (EC 4.2.1.3) (Aconitate hydratase) (Citrate| hydro-lyase) (Fragment) Length = 764 Score = 50.4 bits (119), Expect = 3e-06 Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 16/130 (12%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 A DL+L + + G + +EF G + L++ +R T+ NM E G G P D T Sbjct: 127 ATDLVLTVTQMLRKHGVVGKFVEFYGEGMGELSLADRATIANMSPEYGATMGFFPVDHVT 186 Query: 204 FKYLE--GKTSVEYEPV------------YSDAQA-RFYSDY-RFDVSKLEPVVAKPHSP 335 +YL+ G+ + YS+ Q R YS + ++S +EP ++ P P Sbjct: 187 LQYLKLTGRKDETISMIESYLLANKMFVDYSEPQVERVYSSHIELNLSDVEPCISGPKRP 246 Query: 336 DNRALARECK 365 +R +E K Sbjct: 247 HDRVPLKEMK 256
>IREB2_HUMAN (P48200) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron| regulatory protein 2) (IRP2) Length = 963 Score = 49.7 bits (117), Expect = 6e-06 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 16/134 (11%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P++ + D++L I + G + +EF GS + L++ +R T+ NM E G P Sbjct: 328 PFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPV 387 Query: 192 DETTFKYLE----GKTSVEYEPVYSDAQARFYSD------------YRFDVSKLEPVVAK 323 D T K+LE K +E Y A F +D + +++ + P V+ Sbjct: 388 DNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSG 447 Query: 324 PHSPDNRALARECK 365 P P +R + K Sbjct: 448 PKRPQDRVAVTDMK 461
>ACON_FRATH (Q2A1K3) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 937 Score = 49.3 bits (116), Expect = 8e-06 Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 13/127 (10%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 A DL+L++ + G + +E+ G +ESL++ +R T+ NM E G G P DE T Sbjct: 264 ATDLVLKVTEVLRKHGVVGKFVEYYGEGLESLSLPDRATIANMTPEYGATIGFFPVDEVT 323 Query: 204 FKYLEGKTSVEY----EPVYSD--------AQARFYSD-YRFDVSKLEPVVAKPHSPDNR 344 + E +Y + A+ YS+ D+S++E +A P P +R Sbjct: 324 LDFFNNTNRSELVDAAREMYKEQLLFRENPAEEPEYSNIVEIDLSEVESNLAGPKRPQDR 383 Query: 345 ALARECK 365 + K Sbjct: 384 VAFHDMK 390
>ACON_STAES (Q8CPC2) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 2/104 (1%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGSTATDLALRVTEELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKY--LEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEP 311 P DE + KY L G+ E V Q + FDV K +P Sbjct: 318 PVDEESLKYMKLTGRDEEHIELVKEYLQ---QNHMFFDVEKEDP 358
>ACON_STAEQ (Q5HPJ0) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 2/104 (1%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGSTATDLALRVTEELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKY--LEGKTSVEYEPVYSDAQARFYSDYRFDVSKLEP 311 P DE + KY L G+ E V Q + FDV K +P Sbjct: 318 PVDEESLKYMKLTGRDEEHIELVKEYLQ---QNHMFFDVEKEDP 358
>ACON_MYCAV (O08451) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 961 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 15/143 (10%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 A D++L + + G + +EF G + + + R TL NM E G + P D+ T Sbjct: 283 ATDVVLTVTEICAKHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIFPIDQET 342 Query: 204 FKYLE--GKTSVEYEPV----------YSDAQARFYSDY-RFDVSKLEPVVAKPHSPDNR 344 YL+ G+ + + V + A +S+Y D+S++ P +A P P +R Sbjct: 343 IDYLKFTGRNAEQVALVETYAKEQGLWHDPAHEPAFSEYLELDLSQVVPSIAGPKRPQDR 402 Query: 345 ALARECKDVKIDRV--YIGSCTG 407 + K V +++ Y+G G Sbjct: 403 IALSQAKSVFREQIPSYVGDGDG 425
>ACOC_ARATH (Q42560) Aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate| hydro-lyase) (Aconitase) Length = 898 Score = 47.8 bits (112), Expect = 2e-05 Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 19/135 (14%) Frame = +3 Query: 18 LLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADE 197 + A DL+L + + G + +EF G + L++ +R T+ NM E G G P D Sbjct: 259 MTATDLVLTVTQMLRKHGVVGKFVEFHGEGMRELSLADRATIANMSPEYGATMGFFPVDH 318 Query: 198 TTFKYLE------------------GKTSVEY-EPVYSDAQARFYSDYRFDVSKLEPVVA 320 T +YL K V+Y EP +++ + S ++ +EP V+ Sbjct: 319 VTLQYLRLTGRSDDTVSMIEAYLRANKMFVDYSEP---ESKTVYSSCLELNLEDVEPCVS 375 Query: 321 KPHSPDNRALARECK 365 P P +R +E K Sbjct: 376 GPKRPHDRVPLKEMK 390
>ACON_RICPR (Q9ZCF4) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 878 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 13/120 (10%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 A DL+L I + + +EF G+ + +LT+ +R T+ NM E G G P D+ T Sbjct: 257 ATDLVLTITEILRRKKVVGKFVEFFGNGLRNLTISDRATISNMSPEYGATCGFFPIDQET 316 Query: 204 FKYLE------------GKTSVEYEPVYSDAQARFYSD-YRFDVSKLEPVVAKPHSPDNR 344 KYLE K ++E Y+ + Y++ D+S + +A P P +R Sbjct: 317 LKYLEVTGREITQIKLVEKYAIEQNLWYNCEDTQEYTEVLELDLSTVYSSLAGPKRPQDR 376
>YBHJ_ECOLI (P75764) Hypothetical protein ybhJ| Length = 753 Score = 47.0 bits (110), Expect = 4e-05 Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 39/208 (18%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSG-ATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVP 188 PY+ +D+ L IIG + +G + MEFVG + +L+ + R ++ M E + V Sbjct: 196 PYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQ 255 Query: 189 ADETTFKYL--EGKTSVEYEPVYSDAQARFYSDYRFDVSKLEPVVAKPHSPDN------- 341 DE +L G+ +Y + A + D+S ++P++A P P N Sbjct: 256 TDEEVHNWLALHGRGQ-DYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTL 314 Query: 342 --------RALARECKDV------------------KIDRVYIGSCTGGKTEDFIAAAKV 443 R + E + V K+ + I C+GG E+ IAAA Sbjct: 315 NQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANA 374 Query: 444 FLASGKKVKVPTF---LVPATQKVWMDV 518 G+ TF + P++Q V+MD+ Sbjct: 375 L--RGQSCGNDTFSLAVYPSSQPVFMDL 400
>ACON_RICCN (Q92G90) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 878 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 13/120 (10%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 A DL+L + + + +EF G +++L + +R T+ NM E G G P D+ T Sbjct: 257 ATDLVLTVTEMLRKKKVVGKFVEFFGEGLKNLMIADRATISNMSPEYGATCGFFPIDQET 316 Query: 204 FKYLE----GKTSVEYEPVYSDAQARFYS-----DY----RFDVSKLEPVVAKPHSPDNR 344 KYLE KT + Y+ Q +Y +Y D+S + +A P P +R Sbjct: 317 IKYLELTGREKTQIRLVEQYATEQNLWYDFEHAVEYTEVLELDLSMVHGSLAGPKRPQDR 376
>ACON_STRMU (Q59938) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 888 Score = 47.0 bits (110), Expect = 4e-05 Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 16/175 (9%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 E+P A DL L++ ++ + + +EF G + L++ +R T+ NM E G G Sbjct: 248 ELPKVATATDLALKVTQKLRLENVVGKFVEFFGPGLAGLSLADRATVANMAPEYGATCGY 307 Query: 183 VPADETTFKYLE-GKTSVEYEPVYSDAQAR--FYSD----------YRFDVSKLEPVVAK 323 P D+ T Y++ S E+ + + R Y D D+S ++P ++ Sbjct: 308 FPIDDETLNYMKLTNRSAEHIALTKEYAKRNHLYHDMTNLPSYTKIVEIDLSAIKPSISG 367 Query: 324 PHSPDN---RALARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKVPT 479 P P + A+E + R + G ++ A V G++++V T Sbjct: 368 PKRPQDLIELGQAKEEFQASLVRQFGVRGFGLGADELAKKATVHFDDGQELEVKT 422
>ACON_STAAW (P63434) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 46.6 bits (109), Expect = 5e-05 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGATATDLALRVTQELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKYLE 218 P D+ + KY++ Sbjct: 318 PVDDESLKYMK 328
>ACON_STAAS (Q6G9K9) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 46.6 bits (109), Expect = 5e-05 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGATATDLALRVTQELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKYLE 218 P D+ + KY++ Sbjct: 318 PVDDESLKYMK 328
>ACON_STAAR (Q6GH55) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 46.6 bits (109), Expect = 5e-05 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGATATDLALRVTQELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKYLE 218 P D+ + KY++ Sbjct: 318 PVDDESLKYMK 328
>ACON_STAAN (P99148) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 46.6 bits (109), Expect = 5e-05 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGATATDLALRVTQELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKYLE 218 P D+ + KY++ Sbjct: 318 PVDDESLKYMK 328
>ACON_STAAM (P63433) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 46.6 bits (109), Expect = 5e-05 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGATATDLALRVTQELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKYLE 218 P D+ + KY++ Sbjct: 318 PVDDESLKYMK 328
>ACON_STAAC (Q5HG69) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 901 Score = 46.6 bits (109), Expect = 5e-05 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = +3 Query: 6 MPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVV 185 +P A DL L++ E+ G + +EF G ++ L + +R T+ NM E G G Sbjct: 258 LPQGATATDLALRVTQELRKKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFF 317 Query: 186 PADETTFKYLE 218 P D+ + KY++ Sbjct: 318 PVDDESLKYMK 328
>IREB1_RABIT (Q01059) Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron| regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) Length = 889 Score = 46.2 bits (108), Expect = 7e-05 Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 16/150 (10%) Frame = +3 Query: 12 PYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPA 191 P + + D++L I + G + +EF G + L++ +R T+ NM E G P Sbjct: 253 PLVTSTDIVLTITKHLRQVGVVGKFVEFFGLGVAQLSIADRATIANMCPEYGATATFFPV 312 Query: 192 DETTFKYL--EGKTSVEYEPVYSDAQA----RFYSD----------YRFDVSKLEPVVAK 323 DE + KYL G+ + + + QA R YSD D+ + P + Sbjct: 313 DEVSIKYLVQTGRDESKVKQIRKYLQAVGMFRDYSDPSQDPDFTQVVELDLKTVVPCCSG 372 Query: 324 PHSPDNRALARECKDVKIDRVYIGSCTGGK 413 P P ++ D+K D SC G K Sbjct: 373 PKRPQDKVAV---SDMKKD---FESCLGAK 396
>ACON_BACSU (P09339) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 908 Score = 44.7 bits (104), Expect = 2e-04 Identities = 33/127 (25%), Positives = 54/127 (42%), Gaps = 14/127 (11%) Frame = +3 Query: 3 EMPPYLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGV 182 ++P A DL L++ + G + +EF G I L + +R T+ NM E G G Sbjct: 263 KLPNGTTATDLALKVTQVLREKGVVGKFVEFFGPGIAELPLADRATIANMAPEYGATCGF 322 Query: 183 VPADETTFKYL----EGKTSVEYEPVYSDAQARFYS----DYRF------DVSKLEPVVA 320 P DE YL ++ Y + FY+ D +F D+S++E ++ Sbjct: 323 FPVDEEALNYLRLTGRDPEHIDVVEAYCRSNGLFYTPDAEDPQFTDVVEIDLSQIEANLS 382 Query: 321 KPHSPDN 341 P P + Sbjct: 383 GPKRPQD 389
>ACON_BRAJA (P70920) Aconitate hydratase (EC 4.2.1.3) (Citrate hydro-lyase)| (Aconitase) Length = 906 Score = 44.7 bits (104), Expect = 2e-04 Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 19/169 (11%) Frame = +3 Query: 24 AKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPADETT 203 A DL+L + + G + +EF G ++ L++ ++ T+ NM E G G P D Sbjct: 273 ATDLVLTVTQMLRKLGVVGKFVEFFGPGLDHLSVADKATIANMAPEYGATCGFFPVDAAA 332 Query: 204 FKYLEGKTSVEYEP------VYSDAQARFYS----------DYRFDVSKLEPVVAKPHSP 335 YL KTS P Y+ AQ F + D++ + P +A P P Sbjct: 333 IDYL--KTSGRAAPRVALVQAYAKAQGLFRTAKSADPVFTETLTLDLADVVPSMAGPKRP 390 Query: 336 DNRAL---ARECKDVKIDRVYIGSCTGGKTEDFIAAAKVFLASGKKVKV 473 + R E V + Y KTE+ AK F GKK ++ Sbjct: 391 EGRIALPSVAEGFSVALANEY------KKTEE---PAKRFAVEGKKYEI 430
>IREB2_RAT (Q62751) Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron| regulatory protein 2) (IRP2) Length = 963 Score = 44.3 bits (103), Expect = 2e-04 Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 15/132 (11%) Frame = +3 Query: 15 YLLAKDLILQIIGEISVSGATYRSMEFVGSTIESLTMEERMTLCNMVIEAGGKNGVVPAD 194 ++ + D++L I + G + +EF GS + L++ +R T+ NM E G P D Sbjct: 330 FVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVD 389 Query: 195 ETTFKYLE----GKTSVEYEPVYSDAQARFYSD-----------YRFDVSKLEPVVAKPH 329 T ++LE KT +E Y A F +D + +++ + V+ P Sbjct: 390 NVTLRHLEHTGFDKTKLESMEEYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPK 449 Query: 330 SPDNRALARECK 365 P +R + K Sbjct: 450 RPQDRVAVTDMK 461 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 83,375,968 Number of Sequences: 219361 Number of extensions: 1681007 Number of successful extensions: 5373 Number of sequences better than 10.0: 276 Number of HSP's better than 10.0 without gapping: 4956 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5202 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4815021120 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
