ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags14o13 |
|---|---|
| Clone Library Name | barley_pub |
>YEX2_SCHPO (O13856) Hypothetical WD-repeat protein C1A6.02 in chromosome I| Length = 361 Score = 85.9 bits (211), Expect = 1e-16 Identities = 59/215 (27%), Positives = 104/215 (48%), Gaps = 13/215 (6%) Frame = +3 Query: 48 LPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAIN 227 + L ++ K HK SCR + +SGT ++ +D + +D TG+V ++ I+ Sbjct: 47 ISLVEQWSTKRHKKSCRNISVNESGTEFISVGSDGVLKIADTSTGRVSSKWIVDKNKEIS 106 Query: 228 RLVCL----TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ--ILA 389 + + A+GDD GC+ VWD R H H D+I ++ ++ ++ +A Sbjct: 107 PYSVVQWIENDMVFATGDDNGCVSVWDKRTEG--GIIHTHNDHIDYISSISPFEERYFVA 164 Query: 390 TSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMK---NGQKVVCGTPSGALLLYSWGHF 560 TSGDG LSV R + SE ++E+ + + +K GT SG + L++ G + Sbjct: 165 TSGDGVLSVIDARNFKKPILSEEQDEEMTCGAFTRDQHSKKKFAVGTASGVITLFTKGDW 224 Query: 561 KDCSDRFL----GHAQSVDNLLKLDEETLISAAAD 653 D +DR L H S++ + + D ++L +D Sbjct: 225 GDHTDRILSPIRSHDFSIETITRADSDSLYVGGSD 259
>HETE1_PODAN (Q00808) Vegetatible incompatibility protein HET-E-1| Length = 1356 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/170 (23%), Positives = 67/170 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H S +V F G + +GS D +I D +G L+ G + VA Sbjct: 966 HGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVA 1025 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG D IK+WDT +C T H ++ + + ++ + S D T+ + Sbjct: 1026 SGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTC 1085 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGH 590 E D + S+ +GQ+V G+ G + ++ C+ GH Sbjct: 1086 TQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWD-AASGTCTQTLEGH 1134 Score = 57.4 bits (137), Expect = 4e-08 Identities = 40/174 (22%), Positives = 66/174 (37%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H S +V F G + +GS D +I D +G L+ G + VA Sbjct: 840 HGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSPDRERVA 899 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG D IK+WD +C T H + + + ++ + S D T+ + Sbjct: 900 SGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTC 959 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSV 602 E +LS+ +GQ+V G+ + ++ C+ GH SV Sbjct: 960 TQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTAS-GTCTQTLEGHGGSV 1012 Score = 54.7 bits (130), Expect = 2e-07 Identities = 43/193 (22%), Positives = 80/193 (41%), Gaps = 2/193 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H ++V F G + +GS D +I D +G L+ HGD++ + + V Sbjct: 1050 HGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLE-GHGDSVWSVAFSPDGQRV 1108 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 ASG G IK+WD +C T H ++ + + ++ + S DGT+ + Sbjct: 1109 ASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGT 1168 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL-L 614 E + S+ +GQ+V G+ + ++ C+ GH V ++ Sbjct: 1169 CTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTAS-GTCTQTLEGHGGWVQSVAF 1227 Query: 615 KLDEETLISAAAD 653 D + + S ++D Sbjct: 1228 SPDGQRVASGSSD 1240 Score = 53.9 bits (128), Expect = 4e-07 Identities = 40/192 (20%), Positives = 76/192 (39%), Gaps = 1/192 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H S +V F + +GS D +I D +G L+ HG + + + V Sbjct: 882 HGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLE-GHGGRVQSVAFSPDGQRV 940 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 ASG D IK+WD +C T H + + + ++ + SGD T+ + Sbjct: 941 ASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGT 1000 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLK 617 E + S+ +GQ+V G+ + ++ C+ GH V +++ Sbjct: 1001 CTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTAS-GTCTQTLEGHGGWVQSVVF 1059 Query: 618 LDEETLISAAAD 653 + +++ +D Sbjct: 1060 SPDGQRVASGSD 1071 Score = 47.4 bits (111), Expect = 4e-05 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = +3 Query: 9 ITGELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKV 188 I G + ++ A G + L + H +V F G + +GS D +I D +G Sbjct: 1113 IDGTIKIWDAASGTCTQTL---EGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTC 1169 Query: 189 IARLDDAHGDAINRLVCLTE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV 365 L+ HG + + + VASG IK+WDT +C T H ++ + + Sbjct: 1170 TQTLE-GHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFS 1228 Query: 366 AGSDQILATSGDGTLSV 416 ++ + S D T+ + Sbjct: 1229 PDGQRVASGSSDNTIKI 1245 Score = 38.9 bits (89), Expect = 0.014 Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 1/108 (0%) Frame = +3 Query: 9 ITGELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKV 188 I G + ++ A G + L + H ++V F G + +GS+D +I D +G Sbjct: 1155 IDGTIKIWDAASGTCTQTL---EGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTC 1211 Query: 189 IARLDDAHGDAINRLVCLTE-TTVASGDDAGCIKVWDTRQRSCCNTFH 329 L+ HG + + + VASG IK+WDT +C T + Sbjct: 1212 TQTLE-GHGGWVQSVAFSPDGQRVASGSSDNTIKIWDTASGTCTQTLN 1258
>RCO1_NEUCR (P78706) Transcriptional repressor rco-1| Length = 604 Score = 60.5 bits (145), Expect = 4e-09 Identities = 55/199 (27%), Positives = 91/199 (45%), Gaps = 8/199 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAH----GDAINRLVCLTE 248 H+ VRF G + TG + S DVETG+ + L D + GD R VC + Sbjct: 296 HESVVCCVRFSMDGKYVATG-CNRSAQIYDVETGEKLCILQDENIDLTGDLYIRSVCFSP 354 Query: 249 TT--VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 +A+G + I+VWD + R+ NTFH HE I + + I + SGD T+ + Sbjct: 355 DGKYLATGAEDKLIRVWDIQSRTIRNTFHGHEQDIYSLDFSRDGRTIASGSGDRTVRLWD 414 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSW-GHFKDCSDRFLGHAQS 599 + + S ED + ++ I + Q V G+ ++ ++ G+ + + GH S Sbjct: 415 IETGQNTSVLSI-EDGVTTVAISPDKQFVAAGSLDKSVRVWDMRGYLAERLEGPDGHKDS 473 Query: 600 VDNL-LKLDEETLISAAAD 653 V ++ D L+S + D Sbjct: 474 VYSVAFSPDGRNLVSGSLD 492
>GBB_LYMST (Q08706) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 58.5 bits (140), Expect = 2e-08 Identities = 47/168 (27%), Positives = 68/168 (40%), Gaps = 1/168 (0%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D +++ T S DMS D+ETG+ GD ++ Sbjct: 135 RVSRELPGHTGYLSCCRFIDDNSIV-TSSGDMSCALWDIETGQQTTSFTGHTGDVMSLST 193 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R C TF HE I+ +TY S D T + Sbjct: 194 SPDFRTFVSGACDASAKLWDVRDGMCKQTFSGHESDINAITYFPNGHAFATGSDDATCRL 253 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 +R + + +S D ++ G V + SG LLL + F Sbjct: 254 FDIRAD--QEIGMYSHDNIIC------GITSVAFSKSGRLLLGRYDDF 293
>GBB1_HOMAM (O45040) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 5/158 (3%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RFVD ++ T S DM+ D+ETG+ + GD ++ + Sbjct: 134 RVSRELPGHTGYLSCCRFVDDNQIV-TSSGDMTCALWDIETGQQCTQFTGHTGDVMSLSL 192 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R C TF HE I+ +T+ S D T + Sbjct: 193 SPNMRTFTSGACDASAKLWDIRDGMCRQTFPGHESDINAVTFFPNGHAFATGSDDATCRL 252 Query: 417 NSLRGNRVKSQSEFSEDELL----SLVIMKNGQKVVCG 518 +R + + + +S D ++ S+ K+G+ ++ G Sbjct: 253 FDIRAD--QELAMYSHDNIICGITSVAFSKSGKLLLAG 288
>APAF_MOUSE (O88879) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 57.4 bits (137), Expect = 4e-08 Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 16/189 (8%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 L +F+ G E+L K H+D F + I T SAD + D TGK++ Sbjct: 639 LQVFKAETG---EKLLDIKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTY 695 Query: 201 DDAHGDAINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAG 371 D+ H + +N + +A+G + +K+WD Q+ C NT H + ++ + Sbjct: 696 DE-HSEQVNCCHFTNSSNHLLLATGSNDFFLKLWDLNQKECRNTMFGHTNSVNHCRFSPD 754 Query: 372 SDQILATSGDGTL------SVNSLRGNRVKSQSEFSEDELLSL-VIMK------NGQKVV 512 + + + S DGTL S N + VK SED + VI+K +G K++ Sbjct: 755 DELLASCSADGTLRLWDVRSANERKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDKII 814 Query: 513 CGTPSGALL 539 + LL Sbjct: 815 VAAKNKVLL 823 Score = 42.4 bits (98), Expect = 0.001 Identities = 41/175 (23%), Positives = 71/175 (40%), Gaps = 11/175 (6%) Frame = +3 Query: 48 LPLERLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAI 224 LP R+F+ HK + R ++F G +++ S D I + +TG + AH + + Sbjct: 990 LPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTGDYVFL--QAHQETV 1047 Query: 225 NRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDG 404 L ++ + S G +KVW+ F H+ + + + + +TS D Sbjct: 1048 KDFRLLQDSRLLSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADK 1107 Query: 405 TLSV---------NSLRG-NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALL 539 T + + L+G N S FS D +L NG+ + G LL Sbjct: 1108 TAKIWSFDLLSPLHELKGHNGCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQLL 1162 Score = 38.1 bits (87), Expect = 0.023 Identities = 41/197 (20%), Positives = 73/197 (37%), Gaps = 4/197 (2%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL---T 245 +PH D+ F G I + AD ++ ETG+ + + AH D + L C Sbjct: 612 RPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDI-KAHEDEV--LCCAFSSD 668 Query: 246 ETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSL 425 ++ +A+ +K+WD+ +T+ H + ++ + S+ +L +G Sbjct: 669 DSYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNSSNHLLLATG--------- 719 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVD 605 S D L L + K+C + GH SV+ Sbjct: 720 -----------SNDFFLKLWDLNQ---------------------KECRNTMFGHTNSVN 747 Query: 606 NL-LKLDEETLISAAAD 653 + D+E L S +AD Sbjct: 748 HCRFSPDDELLASCSAD 764
>YY46_ANASP (Q8YRI1) Hypothetical WD-repeat protein alr3466| Length = 1526 Score = 56.6 bits (135), Expect = 6e-08 Identities = 36/197 (18%), Positives = 89/197 (45%), Gaps = 1/197 (0%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 L+ + H +V F G+ + +GS+D ++ ++ + K + H +N +V Sbjct: 1193 LYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTFQ-GHTSWVNSVVFN 1251 Query: 243 TE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVN 419 + + +ASG +++WD C +TF H ++++ + + + + SGD T+ + Sbjct: 1252 PDGSMLASGSSDKTVRLWDISSSKCLHTFQGHTNWVNSVAFNPDGSMLASGSGDQTVRLW 1311 Query: 420 SLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQS 599 + ++ + + S+ +G + G+ + L+S +C FLGH Sbjct: 1312 EISSSKCLHTFQGHTSWVSSVTFSPDGTMLASGSDDQTVRLWSISS-GECLYTFLGHTNW 1370 Query: 600 VDNLLKLDEETLISAAA 650 V +++ + ++++ + Sbjct: 1371 VGSVIFSPDGAILASGS 1387 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/198 (19%), Positives = 82/198 (41%), Gaps = 1/198 (0%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 L+ + H R+V F G ++ +G D + D+ +G + L + Sbjct: 1067 LYTLQGHTSCVRSVVFSPDGAMLASGGDDQIVRLWDISSGNCLYTLQGYTSWVRFLVFSP 1126 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 T+A+G +++WD + C T H ++++ + + + + SGD T+ + Sbjct: 1127 NGVTLANGSSDQIVRLWDISSKKCLYTLQGHTNWVNAVAFSPDGATLASGSGDQTVRLWD 1186 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSV 602 + ++ + + S+V +G + G+ + L+ K C F GH V Sbjct: 1187 ISSSKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSK-CLCTFQGHTSWV 1245 Query: 603 DNLL-KLDEETLISAAAD 653 ++++ D L S ++D Sbjct: 1246 NSVVFNPDGSMLASGSSD 1263 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/192 (18%), Positives = 85/192 (44%), Gaps = 1/192 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H + +V F G+++ +GS D ++ ++ + K + H ++ + + T + Sbjct: 1283 HTNWVNSVAFNPDGSMLASGSGDQTVRLWEISSSKCLHTFQ-GHTSWVSSVTFSPDGTML 1341 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 ASG D +++W C TF H +++ + + + + SGD T+ + S+ + Sbjct: 1342 ASGSDDQTVRLWSISSGECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGK 1401 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLK 617 + + + S+V +G + G+ + L++ +C GH SV ++ Sbjct: 1402 CLYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISS-GECLYTLHGHINSVRSVAF 1460 Query: 618 LDEETLISAAAD 653 + ++++ +D Sbjct: 1461 SSDGLILASGSD 1472 Score = 46.6 bits (109), Expect = 6e-05 Identities = 37/188 (19%), Positives = 77/188 (40%), Gaps = 2/188 (1%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTVASGDD 272 R + F +G + GS+D + D+ + K + L H + +N + + T+ASG Sbjct: 1120 RFLVFSPNGVTLANGSSDQIVRLWDISSKKCLYTLQ-GHTNWVNAVAFSPDGATLASGSG 1178 Query: 273 AGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQS 452 +++WD C H +++ + + + + S D T+ + + ++ Sbjct: 1179 DQTVRLWDISSSKCLYILQGHTSWVNSVVFNPDGSTLASGSSDQTVRLWEINSSKCLCTF 1238 Query: 453 EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL-LKLDEE 629 + + S+V +G + G+ + L+ K C F GH V+++ D Sbjct: 1239 QGHTSWVNSVVFNPDGSMLASGSSDKTVRLWDISSSK-CLHTFQGHTNWVNSVAFNPDGS 1297 Query: 630 TLISAAAD 653 L S + D Sbjct: 1298 MLASGSGD 1305 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/115 (24%), Positives = 54/115 (46%), Gaps = 1/115 (0%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E L+ H + +V F G ++ +GS D ++ + +GK + L H + + +V Sbjct: 1359 ECLYTFLGHTNWVGSVIFSPDGAILASGSGDQTVRLWSISSGKCLYTLQ-GHNNWVGSIV 1417 Query: 237 CLTE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 + T +ASG D +++W+ C T H H + + + + SD ++ SG Sbjct: 1418 FSPDGTLLASGSDDQTVRLWNISSGECLYTLHGHINSVRSVAF--SSDGLILASG 1470 Score = 40.8 bits (94), Expect = 0.004 Identities = 45/205 (21%), Positives = 87/205 (42%), Gaps = 6/205 (2%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E L+ + H +V F G+++ TGS D ++ D+ + + + H + +V Sbjct: 981 ECLYIFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISSSQCFY-IFQGHTSCVRSVV 1039 Query: 237 CLTE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL- 410 ++ +ASG D +++WD +C T H + + + + +LA+ GD + Sbjct: 1040 FSSDGAMLASGSDDQTVRLWDISSGNCLYTLQGHTSCVRSVVF-SPDGAMLASGGDDQIV 1098 Query: 411 ---SVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRF 581 ++S GN + + ++ + LV NG + G+ + L+ K C Sbjct: 1099 RLWDISS--GNCLYTLQGYT-SWVRFLVFSPNGVTLANGSSDQIVRLWDISS-KKCLYTL 1154 Query: 582 LGHAQSVDNL-LKLDEETLISAAAD 653 GH V+ + D TL S + D Sbjct: 1155 QGHTNWVNAVAFSPDGATLASGSGD 1179 Score = 39.7 bits (91), Expect = 0.008 Identities = 35/189 (18%), Positives = 72/189 (38%), Gaps = 1/189 (0%) Frame = +3 Query: 90 SCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTVASG 266 S V F G + TG + + + TGK + H +N + + +ASG Sbjct: 866 SVLTVAFSPDGKLFATGDSGGIVRFWEAATGKELLTCK-GHNSWVNSVGFSQDGKMLASG 924 Query: 267 DDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKS 446 D +++WD C TF H + + + S + + S D T+ + + Sbjct: 925 SDDQTVRLWDISSGQCLKTFKGHTSRVRSVVFSPNSLMLASGSSDQTVRLWDISSGECLY 984 Query: 447 QSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDE 626 + + S+ +G + G+ + L+ C F GH V +++ + Sbjct: 985 IFQGHTGWVYSVAFNLDGSMLATGSGDQTVRLWDISS-SQCFYIFQGHTSCVRSVVFSSD 1043 Query: 627 ETLISAAAD 653 ++++ +D Sbjct: 1044 GAMLASGSD 1052 Score = 39.3 bits (90), Expect = 0.010 Identities = 25/109 (22%), Positives = 54/109 (49%), Gaps = 2/109 (1%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 L+ + H + ++ F GT++ +GS D ++ ++ +G+ + L H +++ + Sbjct: 1403 LYTLQGHNNWVGSIVFSPDGTLLASGSDDQTVRLWNISSGECLYTLH-GHINSVRSVAFS 1461 Query: 243 TETTV-ASGDDAGCIKVWDTRQRSCCNTFHRHEDYIS-DMTYVAGSDQI 383 ++ + ASG D IK+WD + C T + Y ++T V G ++ Sbjct: 1462 SDGLILASGSDDETIKLWDVKTGECIKTLKSEKIYEGMNITSVRGLTEV 1510
>Y2800_ANASP (Q8YTC2) Hypothetical WD-repeat protein alr2800| Length = 1258 Score = 55.8 bits (133), Expect = 1e-07 Identities = 40/158 (25%), Positives = 66/158 (41%) Frame = +3 Query: 42 DGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDA 221 DG L+ L H D R V F G + + +AD +I DV GK + L G Sbjct: 757 DGTCLQTLTG---HTDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWV 813 Query: 222 INRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGD 401 + T+ASG IK+W+ C T+ H + + + Y S +++ SGD Sbjct: 814 RSVAFSADGQTLASGSGDRTIKIWNYHTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGD 873 Query: 402 GTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVC 515 T+ + + + +E+ S+ +GQ + C Sbjct: 874 RTIKLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLAC 911 Score = 50.1 bits (118), Expect = 6e-06 Identities = 42/195 (21%), Positives = 80/195 (41%), Gaps = 2/195 (1%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H R+V F G + +GS D +I + TG+ + + H +++ + ++ Sbjct: 807 KSHTGWVRSVAFSADGQTLASGSGDRTIKIWNYHTGECL-KTYIGHTNSVYSIAYSPDSK 865 Query: 255 V-ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRG 431 + SG IK+WD + C T H H + + + + + S D ++ + + R Sbjct: 866 ILVSGSGDRTIKLWDCQTHICIKTLHGHTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRT 925 Query: 432 NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL 611 + + D L + + Q + G+ + L+ W K S GH + + Sbjct: 926 GQCLKAWYGNTDWALPVAFSPDRQILASGSNDKTVKLWDWQTGKYISS-LEGHTDFIYGI 984 Query: 612 -LKLDEETLISAAAD 653 D +TL SA+ D Sbjct: 985 AFSPDSQTLASASTD 999 Score = 46.2 bits (108), Expect = 8e-05 Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 1/113 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H+ +V F G + + S D +I D++ G + L H D + + + T+ Sbjct: 725 HEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLT-GHTDWVRCVAFSPDGNTL 783 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 AS IK+WD Q C T H ++ + + A + + SGD T+ + Sbjct: 784 ASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLASGSGDRTIKI 836 Score = 45.4 bits (106), Expect = 1e-04 Identities = 39/164 (23%), Positives = 74/164 (45%), Gaps = 2/164 (1%) Frame = +3 Query: 102 VRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTET-TVASGDDAG 278 V F ++ +GS D ++ D +TGK I+ L+ H D I + ++ T+AS Sbjct: 942 VAFSPDRQILASGSNDKTVKLWDWQTGKYISSLE-GHTDFIYGIAFSPDSQTLASASTDS 1000 Query: 279 CIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV-NSLRGNRVKSQSE 455 +++W+ C H D++ + + I S D T+ + N G +K+ SE Sbjct: 1001 SVRLWNISTGQCFQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSE 1060 Query: 456 FSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLG 587 S D++L + +GQ + + ++ L+ C+ R +G Sbjct: 1061 HS-DKILGMAWSPDGQLLASASADQSVRLWDC-----CTGRCVG 1098 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 1/113 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H D AV F G +I TGSAD ++ ++ TG+ + L + H D I + + + Sbjct: 1019 HTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSE-HSDKILGMAWSPDGQLL 1077 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 AS +++WD C H + + + + I S D T+ + Sbjct: 1078 ASASADQSVRLWDCCTGRCVGILRGHSNRVYSAIFSPNGEIIATCSTDQTVKI 1130 Score = 38.5 bits (88), Expect = 0.018 Identities = 42/197 (21%), Positives = 79/197 (40%), Gaps = 6/197 (3%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + +V F G + S D S+ + TG+ + A+ +A Sbjct: 893 HTNEVCSVAFSPDGQTLACVSLDQSVRLWNCRTGQCLKAWYGNTDWALPVAFSPDRQILA 952 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG + +K+WD + ++ H D+I + + S + + S D ++ + ++ + Sbjct: 953 SGSNDKTVKLWDWQTGKYISSLEGHTDFIYGIAFSPDSQTLASASTDSSVRLWNISTGQC 1012 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY--SWGH----FKDCSDRFLGHAQSV 602 D + ++V G+ + G+ + L+ S G + SD+ LG A S Sbjct: 1013 FQILLEHTDWVYAVVFHPQGKIIATGSADCTVKLWNISTGQCLKTLSEHSDKILGMAWSP 1072 Query: 603 DNLLKLDEETLISAAAD 653 D L L SA+AD Sbjct: 1073 DGQL------LASASAD 1083 Score = 37.4 bits (85), Expect = 0.039 Identities = 42/227 (18%), Positives = 89/227 (39%), Gaps = 45/227 (19%) Frame = +3 Query: 108 FVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT--ETTVASGDDAGC 281 F G ++ T D + +V++GK++ + H + + +V E + G D Sbjct: 650 FSPEGQLLATCDTDCHVRVWEVKSGKLLL-ICRGHSNWVRFVVFSPDGEILASCGADEN- 707 Query: 282 IKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR----------- 428 +K+W R C T HE + + + + + + SGD T+ + ++ Sbjct: 708 VKLWSVRDGVCIKTLTGHEHEVFSVAFHPDGETLASASGDKTIKLWDIQDGTCLQTLTGH 767 Query: 429 ------------GNRVKSQS--------EFSEDELL-----------SLVIMKNGQKVVC 515 GN + S + + S+ + L S+ +GQ + Sbjct: 768 TDWVRCVAFSPDGNTLASSAADHTIKLWDVSQGKCLRTLKSHTGWVRSVAFSADGQTLAS 827 Query: 516 GTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL-LKLDEETLISAAAD 653 G+ + ++++ H +C ++GH SV ++ D + L+S + D Sbjct: 828 GSGDRTIKIWNY-HTGECLKTYIGHTNSVYSIAYSPDSKILVSGSGD 873
>U3IP2_HUMAN (O43818) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 55.8 bits (133), Expect = 1e-07 Identities = 46/202 (22%), Positives = 91/202 (45%), Gaps = 11/202 (5%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINR-------LVC 239 H+ S + + I + + D SI+ VE+G+ + + A A + ++C Sbjct: 145 HQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSHVLC 204 Query: 240 LTETT----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 + ++ +ASGD + I +W+ + TF H D +S + + G+ Q+ +TS D + Sbjct: 205 MAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRS 264 Query: 408 LSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLG 587 + V ++ N +D + +L + V G G + + W ++ F G Sbjct: 265 VKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRV--WKIPEESQLVFYG 322 Query: 588 HAQSVDNLLKLDEETLISAAAD 653 H S+D + ++EE ++S A D Sbjct: 323 HQGSIDCIHLINEEHMVSGADD 344
>APAF_RAT (Q9EPV5) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1249 Score = 55.8 bits (133), Expect = 1e-07 Identities = 48/190 (25%), Positives = 83/190 (43%), Gaps = 16/190 (8%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 L +F+ G E+L K H+D F + I T S D + D TGK++ Sbjct: 639 LQVFKAETG---EKLLDIKAHEDEVLCCAFSSDDSYIATCSVDKKVKIWDSGTGKLVHTY 695 Query: 201 DDAHGDAINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAG 371 ++ H + +N ++ +A+G + +K+WD Q+ C NT H + ++ + Sbjct: 696 EE-HSEQVNCCHFTNKSNHLLLATGSNDSFLKLWDLNQKECRNTMFGHTNSVTHCRFSPD 754 Query: 372 SDQILATSGDGTL------SVNSLRGNRVKSQSEFSEDELLSL-VIMK------NGQKVV 512 + + + S DGTL S N + VK SED + VI+K +G +++ Sbjct: 755 DELLASCSADGTLKLWDVRSANEKKSINVKRFFLSSEDPPEDVEVIVKCCSWSADGDRII 814 Query: 513 CGTPSGALLL 542 + LLL Sbjct: 815 VAAKNKVLLL 824 Score = 40.4 bits (93), Expect = 0.005 Identities = 40/175 (22%), Positives = 71/175 (40%), Gaps = 11/175 (6%) Frame = +3 Query: 48 LPLERLFAEK-PHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAI 224 LP R+F+ HK + R ++F G +++ S D I + +T + + AH + + Sbjct: 990 LPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSEDSVIQVWNWQTEEYVFL--QAHQETV 1047 Query: 225 NRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDG 404 L ++ + S G +KVW+ F H+ + + + + +TS D Sbjct: 1048 KDFRLLRDSRLLSWSFDGTVKVWNVITGRIERDFTCHQGTVLSCAISSDATKFSSTSADK 1107 Query: 405 TLSV---------NSLRG-NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALL 539 T + + L+G N S FS D +L NG+ + G LL Sbjct: 1108 TAKIWSFELPSPLHELKGHNSCVRCSAFSLDGILLATGDDNGEIRIWNVSDGQLL 1162 Score = 37.4 bits (85), Expect = 0.039 Identities = 41/197 (20%), Positives = 72/197 (36%), Gaps = 4/197 (2%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL---T 245 +PH D+ F G I + AD ++ ETG+ + + AH D + L C Sbjct: 612 RPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDI-KAHEDEV--LCCAFSSD 668 Query: 246 ETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSL 425 ++ +A+ +K+WD+ +T+ H + ++ + S+ +L +G Sbjct: 669 DSYIATCSVDKKVKIWDSGTGKLVHTYEEHSEQVNCCHFTNKSNHLLLATG--------- 719 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVD 605 S D L L + K+C + GH SV Sbjct: 720 -----------SNDSFLKLWDLNQ---------------------KECRNTMFGHTNSVT 747 Query: 606 NL-LKLDEETLISAAAD 653 + D+E L S +AD Sbjct: 748 HCRFSPDDELLASCSAD 764
>GBB2_CAEEL (Q20636) Guanine nucleotide-binding protein beta subunit 2| Length = 356 Score = 55.5 bits (132), Expect = 1e-07 Identities = 48/164 (29%), Positives = 73/164 (44%), Gaps = 3/164 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGD--AINRLVCLT-ET 251 H F+ S +ILTGS D + DVE+G++I GD AI+ C T T Sbjct: 155 HTSYMSCCTFLRSDNLILTGSGDSTCAIWDVESGQLIQNFHGHTGDVFAIDVPKCDTGNT 214 Query: 252 TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRG 431 +++G D + VWD R C +F HE I+ + + D S D T + LR Sbjct: 215 FISAGADKHSL-VWDIRSGQCVQSFEGHEADINTVRFHPNGDAFATGSDDATCRLFDLRA 273 Query: 432 NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFK 563 +R + E S++ NG V + SG +L +G ++ Sbjct: 274 DR-----QVCVYEKESILFPVNG---VDFSLSGRILFAGYGDYR 309
>GBB5_TAMST (Q80ZD0) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/125 (31%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A F +S ILT S D + DVE+G++ L HG + ++CL Sbjct: 152 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQL---LQSFHGHGAD-VLCLDLAPSE 207 Query: 261 SGD---DAGCIK---VWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 +G+ GC K VWD R C F HE I+ + Y D + S D T + Sbjct: 208 TGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 267 Query: 423 LRGNR 437 LR +R Sbjct: 268 LRADR 272 Score = 30.4 bits (67), Expect = 4.8 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 2/118 (1%) Frame = +3 Query: 69 AEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA--RLDDAHGDAINRLVCL 242 A + H+ +VR+ SG +GS D + D+ + +A + A + L Sbjct: 234 AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 293 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + +G + I VWD + S + HE+ +S + + S D TL V Sbjct: 294 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 351
>GBB5_RABIT (Q6PNB6) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/125 (31%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A F +S ILT S D + DVE+G++ L HG + ++CL Sbjct: 152 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQL---LQSFHGHGAD-VLCLDLAPSE 207 Query: 261 SGD---DAGCIK---VWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 +G+ GC K VWD R C F HE I+ + Y D + S D T + Sbjct: 208 TGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 267 Query: 423 LRGNR 437 LR +R Sbjct: 268 LRADR 272
>GBB5_PONPY (Q5RDY7) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/125 (31%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A F +S ILT S D + DVE+G++ L HG + ++CL Sbjct: 152 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQL---LQSFHGHGAD-VLCLDLAPSE 207 Query: 261 SGD---DAGCIK---VWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 +G+ GC K VWD R C F HE I+ + Y D + S D T + Sbjct: 208 TGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 267 Query: 423 LRGNR 437 LR +R Sbjct: 268 LRADR 272 Score = 30.4 bits (67), Expect = 4.8 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 2/118 (1%) Frame = +3 Query: 69 AEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA--RLDDAHGDAINRLVCL 242 A + H+ +VR+ SG +GS D + D+ + +A + A + L Sbjct: 234 AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 293 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + +G + I VWD + S + HE+ +S + + S D TL V Sbjct: 294 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 351
>U3IP2_MOUSE (Q91WM3) U3 small nucleolar RNA-interacting protein 2 (U3 small| nucleolar ribonucleoproptein-associated 55-kDa protein) (U3 snoRNP-associated 55-kDa protein) (U3-55K) Length = 475 Score = 55.1 bits (131), Expect = 2e-07 Identities = 46/202 (22%), Positives = 89/202 (44%), Gaps = 11/202 (5%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDA-------INRLVC 239 H+ S + I + + D +I+ VETG+ + + A A + ++C Sbjct: 145 HQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQPAGHSSHVLC 204 Query: 240 LTETT----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 + ++ +ASGD + I +W+ + TF H D +S + + G+ Q+ +TS D + Sbjct: 205 MAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRKGTHQLYSTSHDRS 264 Query: 408 LSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLG 587 + V + N +D + +L + V G G + + W ++ F G Sbjct: 265 VKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRV--WKIPEESQLVFYG 322 Query: 588 HAQSVDNLLKLDEETLISAAAD 653 H S+D + ++EE ++S A D Sbjct: 323 HQGSIDCIHLINEEHMVSGADD 344
>GBB5_HUMAN (O14775) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 55.1 bits (131), Expect = 2e-07 Identities = 39/125 (31%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A F +S ILT S D + DVE+G++ L HG + ++CL Sbjct: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQL---LQSFHGHGAD-VLCLDLAPSE 249 Query: 261 SGD---DAGCIK---VWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 +G+ GC K VWD R C F HE I+ + Y D + S D T + Sbjct: 250 TGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 309 Query: 423 LRGNR 437 LR +R Sbjct: 310 LRADR 314 Score = 30.4 bits (67), Expect = 4.8 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 2/118 (1%) Frame = +3 Query: 69 AEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA--RLDDAHGDAINRLVCL 242 A + H+ +VR+ SG +GS D + D+ + +A + A + L Sbjct: 276 AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 335 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + +G + I VWD + S + HE+ +S + + S D TL V Sbjct: 336 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 393
>UTP13_SCHPO (Q9USN3) Probable U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 777 Score = 54.7 bits (130), Expect = 2e-07 Identities = 41/189 (21%), Positives = 80/189 (42%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H A++ G +I + S D +I D TG+V+ L Sbjct: 462 KAHDRDVNAIQVSKDGRIIASASQDKTIKLWDSSTGEVVGVLRGHRRGVWACSFNPFSRQ 521 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 +ASG I++W+ + C T H I + Y++ Q+++ + DG + V SL Sbjct: 522 LASGSGDRTIRIWNVDTQQCVQTLEGHTGAILKLIYISQGTQVVSAAADGLVKVWSLSSG 581 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLL 614 + + ED + +L +G +V G + ++ KD ++ ++ Q+ + Sbjct: 582 ECVATLDNHEDRVWALASRFDGSLLVSGGADAVVSVW-----KDVTEEYIA-KQAEELER 635 Query: 615 KLDEETLIS 641 +++ E L+S Sbjct: 636 RVEAEQLLS 644 Score = 45.1 bits (105), Expect = 2e-04 Identities = 45/207 (21%), Positives = 84/207 (40%), Gaps = 9/207 (4%) Frame = +3 Query: 60 RLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC 239 R+ + K H+ + + T++ TG A+ + D+ G + HG I+ L C Sbjct: 95 RIKSMKAHETPVITMTIDPTNTLLATGGAEGLVKVWDI-AGAYVTHSFRGHGGVISAL-C 152 Query: 240 LTET----TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 + +ASG D +++WD F H I +T+ +L+ S D T Sbjct: 153 FGKHQNTWVLASGADDSRVRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGSRDKT 212 Query: 408 LSV-NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL-YSW---GHFKDCS 572 + V N + + V++ F E + V + +K++ G L+L + W Sbjct: 213 VQVWNIKKRSAVRTIPVFHSVEAIGWVNGQPEEKILYTAGEGNLILAWDWKSGSRLDPGV 272 Query: 573 DRFLGHAQSVDNLLKLDEETLISAAAD 653 D ++ ++ E TL+S +D Sbjct: 273 DTTHSETNAIIQVVPFSENTLLSVHSD 299 Score = 37.4 bits (85), Expect = 0.039 Identities = 32/158 (20%), Positives = 61/158 (38%), Gaps = 3/158 (1%) Frame = +3 Query: 57 ERLFA-EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL 233 ERLF+ +K D A+ ++ + ++ +G+ I + I Sbjct: 51 ERLFSIKKDEDDYVTALAITSDSKKLIAAFRSRLLTIYEIPSGRRIKSMKAHETPVITMT 110 Query: 234 VCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG--DGT 407 + T T +A+G G +KVWD ++F H IS + + + + SG D Sbjct: 111 IDPTNTLLATGGAEGLVKVWDIAGAYVTHSFRGHGGVISALCFGKHQNTWVLASGADDSR 170 Query: 408 LSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGT 521 + + L +R + E + L G ++ G+ Sbjct: 171 VRLWDLNSSRSMAVFEGHSSVIRGLTFEPTGSFLLSGS 208
>GBB5_RAT (P62882) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 353 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/125 (30%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A F +S ILT S D + DVE+G++ L HG + ++CL Sbjct: 152 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQL---LQSFHGHGAD-VLCLDLAPSE 207 Query: 261 SGD---DAGCIK---VWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 +G+ GC K VWD R C F HE ++ + Y D + S D T + Sbjct: 208 TGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYD 267 Query: 423 LRGNR 437 LR +R Sbjct: 268 LRADR 272 Score = 30.4 bits (67), Expect = 4.8 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 2/118 (1%) Frame = +3 Query: 69 AEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA--RLDDAHGDAINRLVCL 242 A + H+ +VR+ SG +GS D + D+ + +A + A + L Sbjct: 234 AFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 293 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + +G + I VWD + S + HE+ +S + + S D TL V Sbjct: 294 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 351
>GBB5_MOUSE (P62881) Guanine nucleotide-binding protein beta subunit 5| (Transducin beta chain 5) (Gbeta5) Length = 395 Score = 54.7 bits (130), Expect = 2e-07 Identities = 38/125 (30%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A F +S ILT S D + DVE+G++ L HG + ++CL Sbjct: 194 HTNYLSACSFTNSDMQILTASGDGTCALWDVESGQL---LQSFHGHGAD-VLCLDLAPSE 249 Query: 261 SGD---DAGCIK---VWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 +G+ GC K VWD R C F HE ++ + Y D + S D T + Sbjct: 250 TGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYD 309 Query: 423 LRGNR 437 LR +R Sbjct: 310 LRADR 314 Score = 30.4 bits (67), Expect = 4.8 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 2/118 (1%) Frame = +3 Query: 69 AEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA--RLDDAHGDAINRLVCL 242 A + H+ +VR+ SG +GS D + D+ + +A + A + L Sbjct: 276 AFETHESDVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSL 335 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + +G + I VWD + S + HE+ +S + + S D TL V Sbjct: 336 SGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 393
>GBB2_RAT (P54313) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 53.9 bits (128), Expect = 4e-07 Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 7/174 (4%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D +I T S D + D+ETG+ GD ++ + Sbjct: 133 RVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSL 191 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG IK+WD R C TF HE I+ + + S D T + Sbjct: 192 APDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRL 251 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCG------TPSGALLLYSWGHF 560 LR ++ ELL M + ++CG + SG LLL + F Sbjct: 252 FDLR----------ADQELL----MYSHDNIICGITSVAFSRSGRLLLAGYDDF 291
>GBB2_MOUSE (P62880) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 53.9 bits (128), Expect = 4e-07 Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 7/174 (4%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D +I T S D + D+ETG+ GD ++ + Sbjct: 133 RVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSL 191 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG IK+WD R C TF HE I+ + + S D T + Sbjct: 192 APDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRL 251 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCG------TPSGALLLYSWGHF 560 LR ++ ELL M + ++CG + SG LLL + F Sbjct: 252 FDLR----------ADQELL----MYSHDNIICGITSVAFSRSGRLLLAGYDDF 291
>GBB2_HUMAN (P62879) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) Length = 339 Score = 53.9 bits (128), Expect = 4e-07 Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 7/174 (4%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D +I T S D + D+ETG+ GD ++ + Sbjct: 133 RVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSL 191 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG IK+WD R C TF HE I+ + + S D T + Sbjct: 192 APDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRL 251 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCG------TPSGALLLYSWGHF 560 LR ++ ELL M + ++CG + SG LLL + F Sbjct: 252 FDLR----------ADQELL----MYSHDNIICGITSVAFSRSGRLLLAGYDDF 291
>GBB1_DROME (P26308) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 53.9 bits (128), Expect = 4e-07 Identities = 42/158 (26%), Positives = 68/158 (43%), Gaps = 5/158 (3%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D ++ T S DMS D+ETG + GD + + Sbjct: 134 RVSRELPGHGGYLSCCRFLDDNQIV-TSSGDMSCGLWDIETGLQVTSFLGHTGDVMALSL 192 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R+ C TF HE I+ +T+ S D T + Sbjct: 193 APQCKTFVSGACDASAKLWDIREGVCKQTFPGHESDINAVTFFPNGQAFATGSDDATCRL 252 Query: 417 NSLRGNRVKSQSEFSEDELL----SLVIMKNGQKVVCG 518 +R + + + +S D ++ S+ K+G+ ++ G Sbjct: 253 FDIRAD--QELAMYSHDNIICGITSVAFSKSGRLLLAG 288
>GBB2_BOVIN (P11017) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 2 (Transducin beta chain 2) (G protein beta 2 subunit) (Fragment) Length = 326 Score = 53.9 bits (128), Expect = 4e-07 Identities = 48/174 (27%), Positives = 69/174 (39%), Gaps = 7/174 (4%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D +I T S D + D+ETG+ GD ++ + Sbjct: 120 RVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSL 178 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG IK+WD R C TF HE I+ + + S D T + Sbjct: 179 APDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRL 238 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCG------TPSGALLLYSWGHF 560 LR ++ ELL M + ++CG + SG LLL + F Sbjct: 239 FDLR----------ADQELL----MYSHDNIICGITSVAFSRSGRLLLAGYDDF 278
>PF20_CHLRE (P93107) Flagellar WD-repeat protein PF20| Length = 606 Score = 53.5 bits (127), Expect = 5e-07 Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 11/170 (6%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT-ETTV 257 HK + +VRF G V+ +GS D ++ D+ GK L H D++N L +++ Sbjct: 409 HKQAIWSVRFHHLGEVVASGSLDHTVRLWDLPAGKCRMALR-GHVDSVNDLAWQPFSSSL 467 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR--- 428 A+ + VWD R C T++ H++ + +++ Q+ +T DG + + R Sbjct: 468 ATASSDKTVSVWDARAGLCTQTYYGHQNSCNGVSFNILGTQLASTDADGVVKLWDTRMTA 527 Query: 429 -------GNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGH 557 G ++S F + V +G+ T G L GH Sbjct: 528 EVATINTGKHPANKSCFDRSGQVLAVACDDGKVKAYSTTDGVLQAELAGH 577 Score = 46.2 bits (108), Expect = 8e-05 Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 2/114 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAI--NRLVCLTETT 254 HKD V F +GT + +G D ++ D E + + D H AI R L E Sbjct: 367 HKDWVAGVDFHPAGTCLASGGGDSAVKIWDFEKQRCVTTFTD-HKQAIWSVRFHHLGE-V 424 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 VASG +++WD C H D ++D+ + S + S D T+SV Sbjct: 425 VASGSLDHTVRLWDLPAGKCRMALRGHVDSVNDLAWQPFSSSLATASSDKTVSV 478 Score = 36.6 bits (83), Expect = 0.067 Identities = 32/153 (20%), Positives = 66/153 (43%), Gaps = 2/153 (1%) Frame = +3 Query: 69 AEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC-LT 245 A + H DS + + + + T S+D ++ D G + + H ++ N + + Sbjct: 447 ALRGHVDSVNDLAWQPFSSSLATASSDKTVSVWDARAG-LCTQTYYGHQNSCNGVSFNIL 505 Query: 246 ETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSL 425 T +AS D G +K+WDTR + T + + + + + DG + S Sbjct: 506 GTQLASTDADGVVKLWDTRMTAEVATINTGKHPANKSCFDRSGQVLAVACDDGKVKAYST 565 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVV-CGT 521 ++++ ED + +++ GQ +V CG+ Sbjct: 566 TDGVLQAELAGHEDAVQAVLFDPAGQYLVSCGS 598 Score = 32.0 bits (71), Expect = 1.7 Identities = 16/65 (24%), Positives = 31/65 (47%) Frame = +3 Query: 249 TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 T +ASG +K+WD ++ C TF H+ I + + + + + S D T+ + L Sbjct: 381 TCLASGGGDSAVKIWDFEKQRCVTTFTDHKQAIWSVRFHHLGEVVASGSLDHTVRLWDLP 440 Query: 429 GNRVK 443 + + Sbjct: 441 AGKCR 445
>Y2124_ANASP (Q8YV57) Hypothetical WD-repeat protein all2124| Length = 1683 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/210 (17%), Positives = 90/210 (42%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 + +++ +DG L+ + H+ + V F G + + S+D SI D +G+++ L Sbjct: 1137 IKLWQTSDGTLLKTITG---HEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQLLMTL 1193 Query: 201 DDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ 380 I T+A+G + +K+W + T + H+D+++ +++ Sbjct: 1194 TGHSAGVITVRFSPDGQTIAAGSEDKTVKLWHRQDGKLLKTLNGHQDWVNSLSFSPDGKT 1253 Query: 381 ILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + + S D T+ + + ++ + D + + +G+ + + + L W Sbjct: 1254 LASASADKTIKLWRIADGKLVKTLKGHNDSVWDVNFSSDGKAIASASRDNTIKL--WNRH 1311 Query: 561 KDCSDRFLGHAQSVDNLLKLDEETLISAAA 650 + F GH+ V + L + +I++A+ Sbjct: 1312 GIELETFTGHSGGVYAVNFLPDSNIIASAS 1341 Score = 45.4 bits (106), Expect = 1e-04 Identities = 44/195 (22%), Positives = 84/195 (43%), Gaps = 4/195 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 HKD ++ G I +GS D +I + G++ L+ H DA+ + + T+ Sbjct: 1071 HKDGVISISISRDGQTIASGSLDKTIKLWSRD-GRLFRTLN-GHEDAVYSVSFSPDGQTI 1128 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 ASG IK+W T + T HE ++++ + + + S D ++ + + Sbjct: 1129 ASGGSDKTIKLWQTSDGTLLKTITGHEQTVNNVYFSPDGKNLASASSDHSIKLWDTTSGQ 1188 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKD--CSDRFLGHAQSVDNL 611 + ++++ +GQ + G+ + L+ H +D GH V++L Sbjct: 1189 LLMTLTGHSAGVITVRFSPDGQTIAAGSEDKTVKLW---HRQDGKLLKTLNGHQDWVNSL 1245 Query: 612 -LKLDEETLISAAAD 653 D +TL SA+AD Sbjct: 1246 SFSPDGKTLASASAD 1260 Score = 42.0 bits (97), Expect = 0.002 Identities = 32/150 (21%), Positives = 68/150 (45%), Gaps = 1/150 (0%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H D V F G +I + SAD +I D +G +I L AH D + + + + Sbjct: 1485 KGHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLP-AHNDLVYSVNFNPDGS 1543 Query: 255 VASGDDAG-CIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRG 431 + + A +K+W + +TF H + + ++ I + S D T+ + + G Sbjct: 1544 MLASTSADKTVKLWRSHDGHLLHTFSGHSNVVYSSSFSPDGRYIASASEDKTVKIWQIDG 1603 Query: 432 NRVKSQSEFSEDELLSLVIMKNGQKVVCGT 521 + + + + + ++S + +G+ ++ G+ Sbjct: 1604 HLLTTLPQ-HQAGVMSAIFSPDGKTLISGS 1632 Score = 35.0 bits (79), Expect = 0.20 Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Frame = +3 Query: 27 MFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDD 206 ++R DG L+ L H + V F G + + S D ++ +V GK L Sbjct: 1430 IWRVRDGKALKTLIG---HDNEVNKVNFSPDGKTLASASRDNTVKLWNVSDGKFKKTLK- 1485 Query: 207 AHGDAINRLVCLTE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQI 383 H D + + + +AS I++WD+ + + H D + + + + Sbjct: 1486 GHTDEVFWVSFSPDGKIIASASADKTIRLWDSFSGNLIKSLPAHNDLVYSVNFNPDGSML 1545 Query: 384 LATSGDGTLSV 416 +TS D T+ + Sbjct: 1546 ASTSADKTVKL 1556
>GBB1_CAEEL (P17343) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 53.1 bits (126), Expect = 7e-07 Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 5/158 (3%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D ++ T S DM+ D+ETG+ GD ++ + Sbjct: 134 RVSRELPGHTGYLSCCRFLDDNQIV-TSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSL 192 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R C TF HE I+ + + + S D T + Sbjct: 193 SPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRL 252 Query: 417 NSLRGNRVKSQSEFSEDELL----SLVIMKNGQKVVCG 518 +R + + + +S D ++ S+ K+G+ + G Sbjct: 253 FDIRAD--QELAMYSHDNIICGITSVAFSKSGRLLFAG 288
>GBB1_CAEBR (Q61ZF6) Guanine nucleotide-binding protein beta subunit 1| Length = 340 Score = 53.1 bits (126), Expect = 7e-07 Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 5/158 (3%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D ++ T S DM+ D+ETG+ GD ++ + Sbjct: 134 RVSRELPGHTGYLSCCRFLDDNQIV-TSSGDMTCALWDIETGQQCTAFTGHTGDVMSLSL 192 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R C TF HE I+ + + + S D T + Sbjct: 193 SPDFRTFISGACDASAKLWDIRDGMCKQTFPGHESDINAVAFFPSGNAFATGSDDATCRL 252 Query: 417 NSLRGNRVKSQSEFSEDELL----SLVIMKNGQKVVCG 518 +R + + + +S D ++ S+ K+G+ + G Sbjct: 253 FDIRAD--QELAMYSHDNIICGITSVAFSKSGRLLFAG 288
>GBB_DICDI (P36408) Guanine nucleotide-binding protein beta subunit| Length = 347 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/116 (29%), Positives = 51/116 (43%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 I+T S DM+ + DVE G I D +GD ++ V + SG K+WD R Sbjct: 164 IVTSSGDMTCILWDVENGTKITEFSDHNGDVMSVSVSPDKNYFISGACDATAKLWDLRSG 223 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELL 476 C TF HE I+ + Y S D + + +R +R Q ++ D +L Sbjct: 224 KCVQTFTGHEADINAVQYFPNGLSFGTGSDDASCRLFDIRADRELMQ--YTHDNIL 277
>YRIQ_CAEEL (P90794) Hypothetical WD-repeat protein D2030.9| Length = 571 Score = 52.0 bits (123), Expect = 2e-06 Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 10/128 (7%) Frame = +3 Query: 75 KPHKDSCRA--VRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC--- 239 +P +D C V+F DS I+ G++ SI DVE + I + +AH D +N VC Sbjct: 263 EPGRDHCAVFCVKFSDSSEQIVCGTSQYSIHVFDVEQRRRIRTIVNAHEDDVNS-VCFAD 321 Query: 240 LTETTVASGDDAGCIKVWDTRQRS-----CCNTFHRHEDYISDMTYVAGSDQILATSGDG 404 L + S D G +KVWD R S F H D ++ + +L+ S D Sbjct: 322 LGSNLIYSAGDDGLVKVWDKRAWSDGDVEPVGVFAGHRDGVTHVDSRQDERYLLSNSKDQ 381 Query: 405 TLSVNSLR 428 T+ V LR Sbjct: 382 TIKVWDLR 389
>GBB_LOLFO (P23232) Guanine nucleotide-binding protein beta subunit| Length = 341 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/168 (26%), Positives = 68/168 (40%), Gaps = 1/168 (0%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D ++ T S DM+ ++ETG I GD ++ + Sbjct: 135 RVSRELPGHTGYLSCCRFIDDNQIV-TSSGDMTCALWNIETGNQITSFGGHTGDVMSLSL 193 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K++D R C TF HE I+ +TY S D T + Sbjct: 194 APDMRTFVSGACDASAKLFDIRDGICKQTFTGHESDINAITYFPNGFAFATGSDDATCRL 253 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 +R + + +S D ++ G V + SG LLL + F Sbjct: 254 FDIRAD--QEIGMYSHDNIIC------GITSVAFSKSGRLLLGGYDDF 293
>GBB1_XENLA (P79959) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) (XGbeta1) Length = 340 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 4/150 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D +I T S D + D+ETG+ GD ++ + Sbjct: 142 HTGYLSCCRFLDDNQII-TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDSRCFV 200 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 201 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 258 Query: 441 KSQSEFSEDELL----SLVIMKNGQKVVCG 518 + +S D ++ S+ K+G+ ++ G Sbjct: 259 QELMVYSHDNIICGITSVAFSKSGRLLLAG 288
>GBB1_RAT (P54311) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/160 (25%), Positives = 63/160 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ + Sbjct: 141 HTGYLSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV 199 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 200 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 257 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + +S D ++ G V + SG LLL + F Sbjct: 258 QELMTYSHDNIIC------GITSVSFSKSGRLLLAGYDDF 291
>GBB1_PONPY (Q5R5W8) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/160 (25%), Positives = 63/160 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ + Sbjct: 141 HTGYLSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV 199 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 200 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 257 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + +S D ++ G V + SG LLL + F Sbjct: 258 QELMTYSHDNIIC------GITSVSFSKSGRLLLAGYDDF 291
>GBB1_MOUSE (P62874) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/160 (25%), Positives = 63/160 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ + Sbjct: 141 HTGYLSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV 199 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 200 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 257 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + +S D ++ G V + SG LLL + F Sbjct: 258 QELMTYSHDNIIC------GITSVSFSKSGRLLLAGYDDF 291
>GBB1_HUMAN (P62873) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/160 (25%), Positives = 63/160 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ + Sbjct: 141 HTGYLSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV 199 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 200 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 257 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + +S D ++ G V + SG LLL + F Sbjct: 258 QELMTYSHDNIIC------GITSVSFSKSGRLLLAGYDDF 291
>GBB1_CANFA (P62872) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/160 (25%), Positives = 63/160 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ + Sbjct: 141 HTGYLSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV 199 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 200 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 257 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + +S D ++ G V + SG LLL + F Sbjct: 258 QELMTYSHDNIIC------GITSVSFSKSGRLLLAGYDDF 291
>GBB1_BOVIN (P62871) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/160 (25%), Positives = 63/160 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ + Sbjct: 141 HTGYLSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV 199 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 200 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 257 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + +S D ++ G V + SG LLL + F Sbjct: 258 QELMTYSHDNIIC------GITSVSFSKSGRLLLAGYDDF 291
>GBB1_BRARE (Q6PH57) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 340 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/150 (24%), Positives = 62/150 (41%), Gaps = 4/150 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ + Sbjct: 142 HTGYLSCCRFLDDNQIV-TSSGDTTCALWDIETGQQTTTFAGHTGDVMSLSLAPDTRLFV 200 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 201 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 258 Query: 441 KSQSEFSEDELL----SLVIMKNGQKVVCG 518 + +S D ++ S+ K+G+ ++ G Sbjct: 259 QELMVYSHDNIICGITSVAFSKSGRLLLAG 288
>TUP1_CANAL (P56093) Transcriptional repressor TUP1| Length = 514 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/161 (24%), Positives = 73/161 (45%), Gaps = 14/161 (8%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDD------------AHGDAI 224 H VRF G I TG + + +V TG+++A+L D A GD Sbjct: 201 HSSVVCCVRFSRDGKFIATG-CNKTTQVFNVTTGELVAKLIDESSNENKDDNTTASGDLY 259 Query: 225 NRLVCLTET--TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 R VC + +A+G + I++WD + HE I + + D++++ SG Sbjct: 260 IRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILRGHEQDIYSLDFFPDGDRLVSGSG 319 Query: 399 DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGT 521 D ++ + LR ++ S + ED + ++ + +G+ + G+ Sbjct: 320 DRSVRIWDLRTSQC-SLTLSIEDGVTTVAVSPDGKLIAAGS 359
>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73| (Transcription initiation factor TFIID 73 kDa subunit) (TAFII-73) Length = 642 Score = 49.3 bits (116), Expect = 1e-05 Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H++ V F + + TGS+D + DV TG + R+ +AH ++ L + ++ Sbjct: 486 HQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTV-RVFNAHHSPVSALCMSADGLSL 544 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVN 419 AS D++G IKVWD R + +F +H + +++ D + SG VN Sbjct: 545 ASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSF--SYDNKILVSGGADTDVN 596
>GBB4_RAT (O35353) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 49.3 bits (116), Expect = 1e-05 Identities = 47/178 (26%), Positives = 72/178 (40%), Gaps = 7/178 (3%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D G +I T S D + D+ETG+ GD ++ + Sbjct: 133 RVSRELPGHTGYLSCCRFLDDGQII-TSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSL 191 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R C +F H I+ +++ S D T + Sbjct: 192 SPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRL 251 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCG------TPSGALLLYSWGHFKDCS 572 LR ++ ELL + + ++CG + SG LLL + F +CS Sbjct: 252 FDLR----------ADQELL----LYSHDNIICGITSVAFSKSGRLLLAGYDDF-NCS 294
>GBB4_MOUSE (P29387) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 49.3 bits (116), Expect = 1e-05 Identities = 47/178 (26%), Positives = 72/178 (40%), Gaps = 7/178 (3%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D G +I T S D + D+ETG+ GD ++ + Sbjct: 133 RVSRELPGHTGYLSCCRFLDDGQII-TSSGDTTCALWDIETGQQTTTFTGHSGDVMSLSL 191 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R C +F H I+ +++ S D T + Sbjct: 192 SPDLKTFVSGACDASSKLWDIRDGMCRQSFTGHISDINAVSFFPSGYAFATGSDDATCRL 251 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCG------TPSGALLLYSWGHFKDCS 572 LR ++ ELL + + ++CG + SG LLL + F +CS Sbjct: 252 FDLR----------ADQELL----LYSHDNIICGITSVAFSKSGRLLLAGYDDF-NCS 294
>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC| 2.7.11.1) Length = 742 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/169 (21%), Positives = 72/169 (42%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 +H++ A G L L + H D RAV F G ++ +GS D ++ DV + A Sbjct: 483 IHVWDVASGDELHTL---EGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAAAEERAVF 539 Query: 201 DDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ 380 + ++ + VASG G ++W+ + H DY+ + + Sbjct: 540 EGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSM 599 Query: 381 ILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPS 527 + + S DGT+ + + + + + + ++SL +G +V G+ S Sbjct: 600 VASGSRDGTIRLWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDS 648 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/157 (20%), Positives = 64/157 (40%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H D AV F G+++ +GS D +I DV TGK L + ++ + Sbjct: 582 KGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPAENVVSLAFSPDGSM 641 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 + G D+ + +WD +TF H D++ + + + + S D T+ + + Sbjct: 642 LVHGSDS-TVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQ 700 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 + E + + S+ G + + G + ++ Sbjct: 701 EEHTTLEGHTEPVHSVAFHPEGTTLASASEDGTIRIW 737 Score = 39.3 bits (90), Expect = 0.010 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 +H++ A G E L + H D RAV F G ++ +GS D +I DV + L Sbjct: 650 VHLWDVASG---EALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTTL 706 Query: 201 DDAHGDAINRLVCLTE-TTVASGDDAGCIKVW 293 + H + ++ + E TT+AS + G I++W Sbjct: 707 -EGHTEPVHSVAFHPEGTTLASASEDGTIRIW 737 Score = 30.8 bits (68), Expect = 3.7 Identities = 19/98 (19%), Positives = 38/98 (38%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 +A G I VWD +T H D++ + + + + S D T+ + + Sbjct: 474 LAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAAA 533 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 ++ E +L + +G V G+ G L++ Sbjct: 534 EERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWN 571
>GBB1_CRIGR (Q6TMK6) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 1 (Transducin beta chain 1) Length = 339 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/160 (24%), Positives = 63/160 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF++ ++ T S D + D+ETG+ GD ++ + Sbjct: 141 HTGYLSCCRFLNDNQIV-TSSEDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV 199 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ C TF HE I+ + + + S D T + LR + Sbjct: 200 SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-- 257 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + +S D ++ G V + SG LLL + F Sbjct: 258 QELMTYSHDNIIC------GITSVSFSKSGRLLLAGYDDF 291
>WDS_DROME (Q9V3J8) Protein will die slowly| Length = 361 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 5/175 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT----E 248 HK V + ++++GS D ++ ++ TGK + L H N + C Sbjct: 113 HKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLK-GHS---NYVFCCNFNPQS 168 Query: 249 TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV-NSL 425 + SG +++WD R C T H D +S + + I+++S DG + ++ Sbjct: 169 NLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA 228 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGH 590 G +K+ + + + NG+ ++ T L L+ + K C + GH Sbjct: 229 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK-CLKTYTGH 282
>GBB3_MOUSE (Q61011) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/160 (24%), Positives = 66/160 (41%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ V Sbjct: 142 HTGYLSCCRFLDDNNIV-TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFI 200 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ +C TF HE I+ + + + I S D + + LR + Sbjct: 201 SGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-- 258 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + + +S++ ++ G V + SG LL + F Sbjct: 259 QELTAYSQESIIC------GITSVAFSLSGRLLFAGYDDF 292
>GBB3_HUMAN (P16520) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/154 (24%), Positives = 62/154 (40%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ V Sbjct: 142 HTGYLSCCRFLDDNNIV-TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFI 200 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ +C TF HE I+ + + + I S D + + LR Sbjct: 201 SGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLR---- 256 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL 542 ++ EL+ + + ++CG S A L Sbjct: 257 ------ADQELICF----SHESIICGITSVAFSL 280
>WDR48_BRARE (Q6PFM9) WD-repeat protein 48| Length = 677 Score = 48.9 bits (115), Expect = 1e-05 Identities = 48/210 (22%), Positives = 91/210 (43%), Gaps = 16/210 (7%) Frame = +3 Query: 72 EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK---VIARLDDAHGDAINRLV-C 239 EK +++ A++ + + T D I V K IA ++ H D +N ++ C Sbjct: 26 EKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEH-HTDWVNDIILC 84 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV--------AGSDQILATS 395 T+ S +KVW+ + C +T H+DY+ + Y AG D+ + Sbjct: 85 CNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144 Query: 396 GDGTLSVNSLRGNRVKSQS-EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCS 572 TL+ + N V + S ++D + SL + + G ++ G+ L ++ + C+ Sbjct: 145 DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQTGTVIISGSTEKVLRVWD---PRTCA 201 Query: 573 D--RFLGHAQSVDN-LLKLDEETLISAAAD 653 + GH +V + LL D +S ++D Sbjct: 202 KLMKLKGHTDNVKSLLLNRDGTQCLSGSSD 231 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 +KDS ++ +GTVI++GS + + D T + +L H D + L+ + T Sbjct: 167 NKDSIYSLAMNQTGTVIISGSTEKVLRVWDPRTCAKLMKL-KGHTDNVKSLLLNRDGTQC 225 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHED 341 SG G I++W Q+ C T+ H++ Sbjct: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 9/130 (6%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDA--------HGDAINR 230 + HKD +A+ + ++ + D I DV T + ++ + D+I Sbjct: 114 RTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYS 173 Query: 231 LVC-LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 L T T + SG ++VWD R + H D + + Q L+ S DGT Sbjct: 174 LAMNQTGTVIISGSTEKVLRVWDPRTCAKLMKLKGHTDNVKSLLLNRDGTQCLSGSSDGT 233 Query: 408 LSVNSLRGNR 437 + + SL R Sbjct: 234 IRLWSLGQQR 243
>GBB2_DROME (P29829) Guanine nucleotide-binding protein beta subunit 2| Length = 346 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 2/155 (1%) Frame = +3 Query: 105 RFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCI 284 RF+D G +I TGS DM I D+E G + GD + T +G Sbjct: 156 RFLDDGHLI-TGSGDMKICHWDLEKGVKTMDFNGHAGDIAGLSLSPDMKTYITGSVDKTA 214 Query: 285 KVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSE 464 K+WD R+ F H+ +S + Y + S D T + LR ++ +Q E + Sbjct: 215 KLWDVREEGHKQMFFGHDMDVSSVCYHPSGFGFASCSEDQTARMYDLRADQQIAQYEPPQ 274 Query: 465 DE--LLSLVIMKNGQKVVCGTPSGALLLYSWGHFK 563 S + +G+ ++CG G ++SW K Sbjct: 275 KNTGFTSCALSTSGRYLMCGGIEGN--VHSWDTMK 307
>PRP19_RAT (Q9JMJ4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Neuronal| differentiation-related gene protein) Length = 504 Score = 48.5 bits (114), Expect = 2e-05 Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 2/177 (1%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 ILTG AD ++V D T +++A L + + ++ V S I++W Sbjct: 237 ILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT 296 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV--KSQSEFSEDELLSL 482 SC HE ++ ++ A D +L++S D + + ++ RV K E S L Sbjct: 297 SCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCA 356 Query: 483 VIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 +G GT + ++ + ++ F GH+ + ++ + ++ AAD Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNVAN-FPGHSGPITSIAFSENGYYLATAAD 412 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/151 (19%), Positives = 68/151 (45%), Gaps = 3/151 (1%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL-DDAHGDAINRLVCLTET 251 + H+ + + +G +L+ S D SD++TG+V+ ++ D+ G ++ + Sbjct: 303 RAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDG 362 Query: 252 TV-ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 + +G IK+WD ++R+ F H I+ + + + + D ++ + LR Sbjct: 363 LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLR 422 Query: 429 G-NRVKSQSEFSEDELLSLVIMKNGQKVVCG 518 K+ + E+ SL+ ++G + G Sbjct: 423 KLKNFKTLQLDNNFEVKSLIFDQSGTYLALG 453
>PRP19_MOUSE (Q99KP6) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (Nuclear matrix protein SNEV) Length = 504 Score = 48.5 bits (114), Expect = 2e-05 Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 2/177 (1%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 ILTG AD ++V D T +++A L + + ++ V S I++W Sbjct: 237 ILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNT 296 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV--KSQSEFSEDELLSL 482 SC HE ++ ++ A D +L++S D + + ++ RV K E S L Sbjct: 297 SCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCA 356 Query: 483 VIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 +G GT + ++ + ++ F GH+ + ++ + ++ AAD Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNVAN-FPGHSGPITSIAFSENGYYLATAAD 412 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/151 (19%), Positives = 68/151 (45%), Gaps = 3/151 (1%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL-DDAHGDAINRLVCLTET 251 + H+ + + +G +L+ S D SD++TG+V+ ++ D+ G ++ + Sbjct: 303 RAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDG 362 Query: 252 TV-ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 + +G IK+WD ++R+ F H I+ + + + + D ++ + LR Sbjct: 363 LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLR 422 Query: 429 G-NRVKSQSEFSEDELLSLVIMKNGQKVVCG 518 K+ + E+ SL+ ++G + G Sbjct: 423 KLKNFKTLQLDNNFEVKSLIFDQSGTYLALG 453
>GBB3_CANFA (P79147) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 48.5 bits (114), Expect = 2e-05 Identities = 39/160 (24%), Positives = 66/160 (41%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ V Sbjct: 142 HTGYLSCCRFLDDNNIV-TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFKLFI 200 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG K+WD R+ +C TF HE I+ + + + I S D + + LR + Sbjct: 201 SGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-- 258 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + + +S++ ++ G V + SG LL + F Sbjct: 259 QELTAYSDESIIC------GITSVAFSLSGRLLFAGYDDF 292
>APAF_HUMAN (O14727) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1248 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 6/138 (4%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 L +F+ G E+L K H+D F I T S D + + TG+++ Sbjct: 639 LQVFKAETG---EKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTY 695 Query: 201 DDAHGDAINRLVCLTETT------VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTY 362 D+ H + +N C T +A+G +K+WD Q+ C NT H + ++ + Sbjct: 696 DE-HSEQVN---CCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751 Query: 363 VAGSDQILATSGDGTLSV 416 + + S DGTL + Sbjct: 752 SPDDKLLASCSADGTLKL 769 Score = 37.0 bits (84), Expect = 0.051 Identities = 25/111 (22%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 +PH D+ F + G I + AD ++ ETG+ + + AH D + L C T Sbjct: 612 RPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEI-KAHEDEV--LCCAFSTD 668 Query: 255 ---VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 +A+ +K+W++ +T+ H + ++ + S +L +G Sbjct: 669 DRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATG 719 Score = 31.6 bits (70), Expect = 2.2 Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 3/110 (2%) Frame = +3 Query: 333 HEDYISDMTYVAGSDQILATSGDGTLSV-NSLRGNRVKSQSEFSEDELLSLVIMKNGQKV 509 HED + + I S D + + NS+ G V + E SE ++ + + Sbjct: 656 HEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSE-QVNCCHFTNSSHHL 714 Query: 510 VCGTPSGALLLYSWG-HFKDCSDRFLGHAQSVDNL-LKLDEETLISAAAD 653 + T S L W + K+C + GH SV++ D++ L S +AD Sbjct: 715 LLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSAD 764
>GBB3_RAT (P52287) Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta| subunit 3 (Transducin beta chain 3) Length = 340 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/119 (26%), Positives = 50/119 (42%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H RF+D ++ T S D + D+ETG+ GD ++ V Sbjct: 142 HTGYLSCCRFLDDNNIV-TSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFI 200 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG K+WD R+ +C TF HE I+ + + + I S D + + LR ++ Sbjct: 201 SGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQ 259
>GBB_CRYPA (O14435) Guanine nucleotide-binding protein beta subunit| Length = 359 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 1/120 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAIN-RLVCLTETTV 257 H RF++ + ILT S DM+ + D+ETG D GD ++ L + T Sbjct: 159 HAGYLSCCRFINDRS-ILTSSGDMTCMKWDIETGTKQIEFADHLGDVMSISLNPTNQNTF 217 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG K+WD R TF HE I+ + + + S D T + +R +R Sbjct: 218 ISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCRLFDIRADR 277
>WDR48_CHICK (Q5F3K4) WD-repeat protein 48| Length = 678 Score = 47.8 bits (112), Expect = 3e-05 Identities = 50/210 (23%), Positives = 90/210 (42%), Gaps = 16/210 (7%) Frame = +3 Query: 72 EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK---VIARLDDAHGDAINRLV-C 239 EK +++ A++ + + T D I V K IA ++ H D +N +V C Sbjct: 26 EKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEH-HTDWVNDIVLC 84 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV--------AGSDQILATS 395 T+ S +KVW+ + C +T H+DY+ + Y AG D+ + Sbjct: 85 CNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144 Query: 396 GDGTLSVNSLRGNRVKSQS-EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCS 572 TL+ + N V + S ++D + SL + + G +V G+ L ++ + C+ Sbjct: 145 DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWD---PRTCA 201 Query: 573 D--RFLGHAQSVDN-LLKLDEETLISAAAD 653 + GH +V LL D +S ++D Sbjct: 202 KLMKLKGHTDNVKALLLNRDGTQCLSGSSD 231 Score = 40.4 bits (93), Expect = 0.005 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 +KDS ++ GTVI++GS + + D T + +L H D + L+ + T Sbjct: 167 NKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLNRDGTQC 225 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHED 341 SG G I++W Q+ C T+ H++ Sbjct: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Score = 38.1 bits (87), Expect = 0.023 Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 13/134 (9%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVET-------------GKVIARLDDAHG 215 + HKD +A+ + ++ + D I DV T + D + Sbjct: 114 RTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYS 173 Query: 216 DAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATS 395 A+N++ T + SG ++VWD R + H D + + Q L+ S Sbjct: 174 LAMNQM----GTVIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGS 229 Query: 396 GDGTLSVNSLRGNR 437 DGT+ + SL R Sbjct: 230 SDGTIRLWSLGQQR 243
>DIP2_YEAST (Q12220) DOM34-interacting protein 2 (U3 small nucleolar| RNA-associated protein 12) (U3 snoRNA-associated protein 12) Length = 943 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/106 (29%), Positives = 52/106 (49%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK + ++F +GT +++GS D +I+ D+ G+V +H D+I C E + Sbjct: 120 HKAAITLLQFDGTGTRLISGSKDSNIIVWDL-VGEVGLYKLRSHKDSITGFWCQGEDWLI 178 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 S G IK+WD + C T H + + +A D +L T+G Sbjct: 179 STSKDGMIKLWDLKTHQCIET---HIAHTGECWGLAVKDDLLITTG 221 Score = 31.2 bits (69), Expect = 2.8 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 12/116 (10%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDA--HGDAINRLVCLTETT----------VAS 263 G +I + D++I D++TG ++++L D G + R E T +A Sbjct: 39 GQLITSALEDVNIW--DIKTGDLVSKLSDGLPPGASDARGAKPAECTYLEAHKDTDLLAV 96 Query: 264 GDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRG 431 G G IKVWD ++ F+ H+ I+ + + ++++ S D + V L G Sbjct: 97 GYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWDLVG 152
>UTP13_YEAST (Q05946) U3 small nucleolar RNA-associated protein 13 (U3| snoRNA-associated protein 13) Length = 817 Score = 47.4 bits (111), Expect = 4e-05 Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 5/112 (4%) Frame = +3 Query: 117 SGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-----VASGDDAGC 281 + T++ G D SI+ D+E G I HG I+ L + +ASGD G Sbjct: 113 TSTLLAVGGTDGSIIVVDIENG-YITHSFKGHGGTISSLKFYGQLNSKIWLLASGDTNGM 171 Query: 282 IKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 +KVWD +R C +T H + V G D I D S+N L G R Sbjct: 172 VKVWDLVKRKCLHTLQEH------TSAVRGLDIIEVPDNDEP-SLNLLSGGR 216 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/190 (16%), Positives = 72/190 (37%) Frame = +3 Query: 66 FAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT 245 + H+ A+ + ++ T S D + ++E G++ A L + + C Sbjct: 485 YTRHAHEKDINALSVSPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQY 544 Query: 246 ETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSL 425 + +A+ +K+W S T H + + +++ Q+++ DG + + Sbjct: 545 DKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIWDC 604 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVD 605 + + L +L M +G +V G + KDC+++ + Q Sbjct: 605 SSGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQFW-----KDCTEQEIEEEQEKA 659 Query: 606 NLLKLDEETL 635 L E++L Sbjct: 660 KLQVEQEQSL 669
>SEL10_CAEEL (Q93794) F-box/WD-repeat protein sel-10 (Suppressor/enhancer of| lin-12) (Sel-10 protein) Length = 587 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/100 (28%), Positives = 50/100 (50%) Frame = +3 Query: 117 SGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWD 296 +G++++TGS D ++ DVE+G+ +A L H A R V TTV SG +K+W+ Sbjct: 347 AGSILVTGSRDTTLRVWDVESGRHLATLHGHH--AAVRCVQFDGTTVVSGGYDFTVKIWN 404 Query: 297 TRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 C T H + + + + + + + S D ++ V Sbjct: 405 AHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRV 444 Score = 37.0 bits (84), Expect = 0.051 Identities = 43/176 (24%), Positives = 71/176 (40%), Gaps = 1/176 (0%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQ 305 V++TGS D ++ ++ G+V+ L G + + SG +KVW T Sbjct: 268 VLVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVD 327 Query: 306 RSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNRVKSQSEFSEDELLSL 482 S +T H + M +AGS IL T S D TL V + R + Sbjct: 328 GSLLHTLQGHTSTVRCMA-MAGS--ILVTGSRDTTLRVWDVESGR--HLATLHGHHAAVR 382 Query: 483 VIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAA 650 + +G VV G + +++ H C GH V +LL E +++ + + Sbjct: 383 CVQFDGTTVVSGGYDFTVKIWN-AHTGRCIRTLTGHNNRVYSLLFESERSIVCSGS 437 Score = 32.7 bits (73), Expect = 0.97 Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 3/95 (3%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + R V+F GT +++G D ++ + TG+ I L + + L + V Sbjct: 377 HHAAVRCVQF--DGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVC 434 Query: 261 SGDDAGCIKVWDTRQ---RSCCNTFHRHEDYISDM 356 SG I+VWD + + C H S M Sbjct: 435 SGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGM 469
>COPB2_MOUSE (O55029) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 47.0 bits (110), Expect = 5e-05 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 4/173 (2%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VCLTETTVASGDD 272 RA +FV ++TG+ DM I + T + + + +AH D I + V T+ + + D Sbjct: 61 RAAKFVARKNWVVTGADDMQIRVFNYNTLERV-HMFEAHSDYIRCIAVHPTQPFILTSSD 119 Query: 273 AGCIKVWD-TRQRSCCNTFHRHEDYISDMTY-VAGSDQILATSGDGTLSVNSLRGNRVKS 446 IK+WD ++ SC F H Y+ + ++Q + S D T+ V L + Sbjct: 120 DMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNF 179 Query: 447 QSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGH-FKDCSDRFLGHAQSV 602 E E + + G K + + L+ W + K C GHAQ+V Sbjct: 180 TLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNV 232 Score = 40.8 bits (94), Expect = 0.004 Identities = 20/94 (21%), Positives = 43/94 (45%) Frame = +3 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG D +K+WD + ++C T H +S ++ I+ S DGT+ + R+ Sbjct: 204 SGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRL 263 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL 542 +S + + + + ++ V G G++++ Sbjct: 264 ESTLNYGMERVWCVASLRGSNNVALGYDEGSIIV 297 Score = 37.0 bits (84), Expect = 0.051 Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 2/129 (1%) Frame = +3 Query: 18 ELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIAR 197 ++ +F Y LER+ + H D R + + ILT S DM I D + ++ Sbjct: 80 QIRVFNYNT---LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQ 136 Query: 198 LDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAG 371 + + H + ++V + AS IKVW S T HE ++ + Y +G Sbjct: 137 VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSG 196 Query: 372 SDQILATSG 398 D+ SG Sbjct: 197 GDKPYLISG 205
>COPB2_HUMAN (P35606) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 47.0 bits (110), Expect = 5e-05 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 4/173 (2%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VCLTETTVASGDD 272 RA +FV ++TG+ DM I + T + + + +AH D I + V T+ + + D Sbjct: 60 RAAKFVARKNWVVTGADDMQIRVFNYNTLERV-HMFEAHSDYIRCIAVHPTQPFILTSSD 118 Query: 273 AGCIKVWD-TRQRSCCNTFHRHEDYISDMTY-VAGSDQILATSGDGTLSVNSLRGNRVKS 446 IK+WD ++ SC F H Y+ + ++Q + S D T+ V L + Sbjct: 119 DMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNF 178 Query: 447 QSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGH-FKDCSDRFLGHAQSV 602 E E + + G K + + L+ W + K C GHAQ+V Sbjct: 179 TLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNV 231 Score = 40.8 bits (94), Expect = 0.004 Identities = 20/94 (21%), Positives = 43/94 (45%) Frame = +3 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG D +K+WD + ++C T H +S ++ I+ S DGT+ + R+ Sbjct: 203 SGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRL 262 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL 542 +S + + + + ++ V G G++++ Sbjct: 263 ESTLNYGMERVWCVASLRGSNNVALGYDEGSIIV 296 Score = 37.0 bits (84), Expect = 0.051 Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 2/129 (1%) Frame = +3 Query: 18 ELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIAR 197 ++ +F Y LER+ + H D R + + ILT S DM I D + ++ Sbjct: 79 QIRVFNYNT---LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQ 135 Query: 198 LDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAG 371 + + H + ++V + AS IKVW S T HE ++ + Y +G Sbjct: 136 VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSG 195 Query: 372 SDQILATSG 398 D+ SG Sbjct: 196 GDKPYLISG 204
>COPB2_BOVIN (P35605) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 905 Score = 47.0 bits (110), Expect = 5e-05 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 4/173 (2%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VCLTETTVASGDD 272 RA +FV ++TG+ DM I + T + + + +AH D I + V T+ + + D Sbjct: 60 RAAKFVARKNWVVTGADDMQIRVFNYNTLERV-HMFEAHSDYIRCIAVHPTQPFILTSSD 118 Query: 273 AGCIKVWD-TRQRSCCNTFHRHEDYISDMTY-VAGSDQILATSGDGTLSVNSLRGNRVKS 446 IK+WD ++ SC F H Y+ + ++Q + S D T+ V L + Sbjct: 119 DMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNF 178 Query: 447 QSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGH-FKDCSDRFLGHAQSV 602 E E + + G K + + L+ W + K C GHAQ+V Sbjct: 179 TLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNV 231 Score = 40.8 bits (94), Expect = 0.004 Identities = 20/94 (21%), Positives = 43/94 (45%) Frame = +3 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG D +K+WD + ++C T H +S ++ I+ S DGT+ + R+ Sbjct: 203 SGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRL 262 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL 542 +S + + + + ++ V G G++++ Sbjct: 263 ESTLNYGMERVWCVASLRGSNNVALGYDEGSIIV 296 Score = 37.0 bits (84), Expect = 0.051 Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 2/129 (1%) Frame = +3 Query: 18 ELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIAR 197 ++ +F Y LER+ + H D R + + ILT S DM I D + ++ Sbjct: 79 QIRVFNYNT---LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQ 135 Query: 198 LDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAG 371 + + H + ++V + AS IKVW S T HE ++ + Y +G Sbjct: 136 VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSG 195 Query: 372 SDQILATSG 398 D+ SG Sbjct: 196 GDKPYLISG 204
>WDR48_MACFA (Q4R2Z6) WD-repeat protein 48| Length = 622 Score = 47.0 bits (110), Expect = 5e-05 Identities = 50/210 (23%), Positives = 90/210 (42%), Gaps = 16/210 (7%) Frame = +3 Query: 72 EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK---VIARLDDAHGDAINRLV-C 239 EK +++ A++ + + T D I V K IA ++ H D +N +V C Sbjct: 26 EKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEH-HTDWVNDIVLC 84 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV--------AGSDQILATS 395 T+ S +KVW+ + C +T H+DY+ + Y AG D+ + Sbjct: 85 CNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144 Query: 396 GDGTLSVNSLRGNRVKSQS-EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCS 572 TL+ + N V + S ++D + SL + + G +V G+ L ++ + C+ Sbjct: 145 DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWD---PRTCA 201 Query: 573 D--RFLGHAQSVDN-LLKLDEETLISAAAD 653 + GH +V LL D +S ++D Sbjct: 202 KLMKLKGHTDNVKALLLNRDGTQCLSGSSD 231 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 +KDS ++ GT+I++GS + + D T + +L H D + L+ + T Sbjct: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLNRDGTQC 225 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHED 341 SG G I++W Q+ C T+ H++ Sbjct: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 13/134 (9%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVET-------------GKVIARLDDAHG 215 + HKD +A+ + ++ + D I DV T + D + Sbjct: 114 RTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYS 173 Query: 216 DAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATS 395 A+N+L T + SG ++VWD R + H D + + Q L+ S Sbjct: 174 LAMNQL----GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGS 229 Query: 396 GDGTLSVNSLRGNR 437 DGT+ + SL R Sbjct: 230 SDGTIRLWSLGQQR 243
>WDR5_MOUSE (P61965) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| (WD-repeat protein BIG-3) Length = 334 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 5/175 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT----E 248 HK V + ++++ S D ++ DV +GK + L H N + C Sbjct: 86 HKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK-GHS---NYVFCCNFNPQS 141 Query: 249 TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV-NSL 425 + SG +++WD + C T H D +S + + I+++S DG + ++ Sbjct: 142 NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA 201 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGH 590 G +K+ + + + NG+ ++ T L L+ + K C + GH Sbjct: 202 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK-CLKTYTGH 255
>WDR5_HUMAN (P61964) WD-repeat protein 5 (BMP2-induced 3-kb gene protein)| Length = 334 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 5/175 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT----E 248 HK V + ++++ S D ++ DV +GK + L H N + C Sbjct: 86 HKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK-GHS---NYVFCCNFNPQS 141 Query: 249 TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV-NSL 425 + SG +++WD + C T H D +S + + I+++S DG + ++ Sbjct: 142 NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA 201 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGH 590 G +K+ + + + NG+ ++ T L L+ + K C + GH Sbjct: 202 SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGK-CLKTYTGH 255
>WDR48_PONPY (Q5RAW8) WD-repeat protein 48| Length = 677 Score = 47.0 bits (110), Expect = 5e-05 Identities = 50/210 (23%), Positives = 90/210 (42%), Gaps = 16/210 (7%) Frame = +3 Query: 72 EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK---VIARLDDAHGDAINRLV-C 239 EK +++ A++ + + T D I V K IA ++ H D +N +V C Sbjct: 26 EKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEH-HTDWVNDIVLC 84 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV--------AGSDQILATS 395 T+ S +KVW+ + C +T H+DY+ + Y AG D+ + Sbjct: 85 CNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144 Query: 396 GDGTLSVNSLRGNRVKSQS-EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCS 572 TL+ + N V + S ++D + SL + + G +V G+ L ++ + C+ Sbjct: 145 DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWD---PRTCA 201 Query: 573 D--RFLGHAQSVDN-LLKLDEETLISAAAD 653 + GH +V LL D +S ++D Sbjct: 202 KLMKLKGHTDNVKALLLNRDGTQCLSGSSD 231 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 +KDS ++ GT+I++GS + + D T + +L H D + L+ + T Sbjct: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLNRDGTQC 225 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHED 341 SG G I++W Q+ C T+ H++ Sbjct: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 13/134 (9%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVET-------------GKVIARLDDAHG 215 + HKD +A+ + ++ + D I DV T + D + Sbjct: 114 RTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYS 173 Query: 216 DAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATS 395 A+N+L T + SG ++VWD R + H D + + Q L+ S Sbjct: 174 LAMNQL----GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGS 229 Query: 396 GDGTLSVNSLRGNR 437 DGT+ + SL R Sbjct: 230 SDGTIRLWSLGQQR 243
>WDR48_HUMAN (Q8TAF3) WD-repeat protein 48 (WD repeat endosomal protein) (p80)| Length = 677 Score = 47.0 bits (110), Expect = 5e-05 Identities = 50/210 (23%), Positives = 90/210 (42%), Gaps = 16/210 (7%) Frame = +3 Query: 72 EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK---VIARLDDAHGDAINRLV-C 239 EK +++ A++ + + T D I V K IA ++ H D +N +V C Sbjct: 26 EKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEH-HTDWVNDIVLC 84 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV--------AGSDQILATS 395 T+ S +KVW+ + C +T H+DY+ + Y AG D+ + Sbjct: 85 CNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144 Query: 396 GDGTLSVNSLRGNRVKSQS-EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCS 572 TL+ + N V + S ++D + SL + + G +V G+ L ++ + C+ Sbjct: 145 DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWD---PRTCA 201 Query: 573 D--RFLGHAQSVDN-LLKLDEETLISAAAD 653 + GH +V LL D +S ++D Sbjct: 202 KLMKLKGHTDNVKALLLNRDGTQCLSGSSD 231 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 +KDS ++ GT+I++GS + + D T + +L H D + L+ + T Sbjct: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLNRDGTQC 225 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHED 341 SG G I++W Q+ C T+ H++ Sbjct: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 13/134 (9%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVET-------------GKVIARLDDAHG 215 + HKD +A+ + ++ + D I DV T + D + Sbjct: 114 RTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYS 173 Query: 216 DAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATS 395 A+N+L T + SG ++VWD R + H D + + Q L+ S Sbjct: 174 LAMNQL----GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGS 229 Query: 396 GDGTLSVNSLRGNR 437 DGT+ + SL R Sbjct: 230 SDGTIRLWSLGQQR 243
>PRP19_HUMAN (Q9UMS4) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog) (Nuclear| matrix protein 200) (hPso4) Length = 504 Score = 47.0 bits (110), Expect = 5e-05 Identities = 38/177 (21%), Positives = 75/177 (42%), Gaps = 2/177 (1%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 ILTG AD ++V D + +++A L + + ++ V S I++W Sbjct: 237 ILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNA 296 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV--KSQSEFSEDELLSL 482 SC HE ++ ++ A D +L++S D + + ++ RV K E S L Sbjct: 297 SCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCA 356 Query: 483 VIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 +G GT + ++ + ++ F GH+ + ++ + ++ AAD Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTNVAN-FPGHSGPITSIAFSENGYYLATAAD 412 Score = 39.3 bits (90), Expect = 0.010 Identities = 30/151 (19%), Positives = 68/151 (45%), Gaps = 3/151 (1%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL-DDAHGDAINRLVCLTET 251 + H+ + + +G +L+ S D SD++TG+V+ ++ D+ G ++ + Sbjct: 303 RAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDG 362 Query: 252 TV-ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 + +G IK+WD ++R+ F H I+ + + + + D ++ + LR Sbjct: 363 LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLR 422 Query: 429 G-NRVKSQSEFSEDELLSLVIMKNGQKVVCG 518 K+ + E+ SL+ ++G + G Sbjct: 423 KLKNFKTLQLDNNFEVKSLIFDQSGTYLALG 453
>TUP12_SCHPO (Q9UUG8) Transcriptional repressor tup12| Length = 586 Score = 46.6 bits (109), Expect = 6e-05 Identities = 44/191 (23%), Positives = 85/191 (44%), Gaps = 7/191 (3%) Frame = +3 Query: 102 VRFVDSGTVILTGSADMSIVASDVETGKVIARLDDA----HGDAINRLVCLTETT--VAS 263 VRF G + TG + + + +VETGK+I L + GD R V + +A+ Sbjct: 293 VRFSADGKFLATG-CNRAAMVFNVETGKLITLLQEESSKREGDLYVRSVAFSPDGKYLAT 351 Query: 264 GDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVK 443 G + I++WD Q+ HE I + + +++ SGD T+ + + K Sbjct: 352 GVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRTVCLWDVEAGEQK 411 Query: 444 SQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL-LKL 620 ++D + +++ +GQ + G+ + + W ++ GH +SV ++ Sbjct: 412 LILH-TDDGVTTVMFSPDGQFIAAGSLDKVIRI--WTSSGTLVEQLHGHEESVYSVAFSP 468 Query: 621 DEETLISAAAD 653 D + L+S + D Sbjct: 469 DGKYLVSGSLD 479
>WDR57_HUMAN (Q96DI7) WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5| snRNP-specific 40 kDa protein) (38 kDa splicing factor) Length = 357 Score = 46.2 bits (108), Expect = 8e-05 Identities = 56/250 (22%), Positives = 92/250 (36%), Gaps = 57/250 (22%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAIN--------- 227 K H + + + G+++ + S D ++ D ETG+ + RL H +N Sbjct: 106 KGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLK-GHTSFVNSCYPARRGP 164 Query: 228 RLVCL----------------------------------TETTVASGDDAGCIKVWDTRQ 305 +LVC T + SG IKVWD RQ Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQ 224 Query: 306 RSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQS--------EFS 461 T H D ++ ++ + +L+ + D T+ V +R K + Sbjct: 225 NKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNF 284 Query: 462 EDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFL-----GHAQSVDNL-LKLD 623 E LL +G K+ G S +Y W D + R + GHA S++ + D Sbjct: 285 EKNLLRCSWSPDGSKIAAG--SADRFVYVW----DTTSRRILYKLPGHAGSINEVAFHPD 338 Query: 624 EETLISAAAD 653 E +ISA++D Sbjct: 339 EPIIISASSD 348
>WDR48_MOUSE (Q8BH57) WD-repeat protein 48| Length = 676 Score = 46.2 bits (108), Expect = 8e-05 Identities = 47/196 (23%), Positives = 84/196 (42%), Gaps = 15/196 (7%) Frame = +3 Query: 72 EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK---VIARLDDAHGDAINRLV-C 239 EK +++ A++ + + T D I V K IA ++ H D +N +V C Sbjct: 26 EKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEH-HTDWVNDVVLC 84 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV--------AGSDQILATS 395 T+ S +KVW+ + C +T H+DY+ + Y AG D+ + Sbjct: 85 CNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLW 144 Query: 396 GDGTLSVNSLRGNRVKSQS-EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCS 572 TL+ + N V + S ++D + SL + + G +V G+ L ++ + C+ Sbjct: 145 DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWD---PRTCA 201 Query: 573 D--RFLGHAQSVDNLL 614 + GH +V LL Sbjct: 202 KLMKLKGHTDNVKALL 217 Score = 39.7 bits (91), Expect = 0.008 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 +KDS ++ GT+I++GS + + D T + +L H D + L+ + T Sbjct: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLK-GHTDNVKALLLHRDGTQC 225 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHED 341 SG G I++W Q+ C T+ H++ Sbjct: 226 LSGSSDGTIRLWSLGQQRCIATYRVHDE 253 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 13/134 (9%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVET-------------GKVIARLDDAHG 215 + HKD +A+ + ++ + D I DV T + D + Sbjct: 114 RTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYS 173 Query: 216 DAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATS 395 A+N+L T + SG ++VWD R + H D + + Q L+ S Sbjct: 174 LAMNQL----GTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGS 229 Query: 396 GDGTLSVNSLRGNR 437 DGT+ + SL R Sbjct: 230 SDGTIRLWSLGQQR 243
>PRP19_CHICK (Q5ZMA2) Pre-mRNA-splicing factor 19 (PRP19/PSO4 homolog)| Length = 505 Score = 46.2 bits (108), Expect = 8e-05 Identities = 37/177 (20%), Positives = 75/177 (42%), Gaps = 2/177 (1%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 ILTG AD +++ D + +++A L + + ++ V S I++W Sbjct: 238 ILTGGADKNVIVFDKSSEQILATLKGHSKKVTSVVFHPSQDLVFSASPDATIRIWSVPNA 297 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV--KSQSEFSEDELLSL 482 SC HE ++ ++ A D +L++S D + + ++ RV K E S L Sbjct: 298 SCVQVVRAHEGSVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDESSGCALTCA 357 Query: 483 VIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 +G GT + ++ + ++ F GH+ + ++ + ++ AAD Sbjct: 358 QFHPDGLIFGTGTMDSQIKIWDLKERTNVAN-FPGHSGPITSIAFSENGYYLATAAD 413 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/151 (21%), Positives = 69/151 (45%), Gaps = 3/151 (1%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL-DDAHGDAINRLVCLTET 251 + H+ S + +G +L+ S D SD++TG+V+ ++ D++ G A+ + Sbjct: 304 RAHEGSVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDESSGCALTCAQFHPDG 363 Query: 252 TV-ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 + +G IK+WD ++R+ F H I+ + + + + D ++ + LR Sbjct: 364 LIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLR 423 Query: 429 G-NRVKSQSEFSEDELLSLVIMKNGQKVVCG 518 K+ + E+ SL+ ++G + G Sbjct: 424 KLKNFKTLQLDNNFEVKSLIFDQSGTYLALG 454
>WD51B_HUMAN (Q8TC44) WD-repeat protein 51B| Length = 478 Score = 46.2 bits (108), Expect = 8e-05 Identities = 34/161 (21%), Positives = 65/161 (40%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 L++ H R +F G +I++ S D +I D + + D+ G A Sbjct: 137 LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNP 196 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + T +AS +KVWD R + H ++ +++ + ++ S DGTL + Sbjct: 197 SGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILD 256 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 L R+ + + ++ K G+ G +LL+ Sbjct: 257 LLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
>SCAP_HUMAN (Q12770) Sterol regulatory element-binding protein| cleavage-activating protein (SREBP cleavage-activating protein) (SCAP) Length = 1278 Score = 45.8 bits (107), Expect = 1e-04 Identities = 51/188 (27%), Positives = 84/188 (44%), Gaps = 8/188 (4%) Frame = +3 Query: 6 LITGE----LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDV 173 L+TG L +FR D L F + H + V ++D V+ +G D +I DV Sbjct: 1091 LVTGSQDHTLRVFRLEDSCCL---FTLQGHSGAITTV-YIDQTMVLASGGQDGAICLWDV 1146 Query: 174 ETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHR-HEDYIS 350 TG ++ + GD + L C T ++SG D I +WD RS F+ +D Sbjct: 1147 LTGSRVSHVFAHRGD-VTSLTCTTSCVISSGLD-DLISIWD---RSTGIKFYSIQQDLGC 1201 Query: 351 DMTYVAGSDQILATSGDGTLSVNSLR-GNRVKS--QSEFSEDELLSLVIMKNGQKVVCGT 521 + SD +L T G G +S L G+ +++ + SE + +++ + +VC Sbjct: 1202 GASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNF 1261 Query: 522 PSGALLLY 545 S L+Y Sbjct: 1262 GSELSLVY 1269
>TUP1_KLULA (P56094) Transcriptional repressor TUP1| Length = 682 Score = 45.8 bits (107), Expect = 1e-04 Identities = 46/201 (22%), Positives = 87/201 (43%), Gaps = 15/201 (7%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDA 275 R+V F G + TG+ D I D+ET K++ L D + + + SG Sbjct: 410 RSVCFSPDGKFLATGAEDKLIRIWDLETKKIVMTLKGHEQDIYSLDYFPSGNKLVSGSGD 469 Query: 276 GCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSV----NSLRGNRV 440 +++WD +C T ED ++ + G + +A S D T+ V R+ Sbjct: 470 RTVRIWDLTTGTCSLTL-SIEDGVTTVAVSPGEGKFIAAGSLDRTVRVWDSDTGFLVERL 528 Query: 441 KSQSEFS---EDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFK------DCSDRFLGHA 593 S++E D + S+V ++G+ VV G+ ++ L++ +C + GH Sbjct: 529 DSENELGTGHRDSVYSVVFTRDGKGVVSGSLDRSVKLWNLNGLSGQKSHAECEVTYTGHK 588 Query: 594 QSVDNLLKL-DEETLISAAAD 653 V ++ ++E ++S + D Sbjct: 589 DFVLSVATTQNDEYILSGSKD 609 Score = 37.0 bits (84), Expect = 0.051 Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 2/96 (2%) Frame = +3 Query: 135 TGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTRQR 308 T +++ + +++ TG + A D R VC + +A+G + I++WD + Sbjct: 379 TSTSNSNGSSAEDGTGNQNSAASTASSDLYIRSVCFSPDGKFLATGAEDKLIRIWDLETK 438 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T HE I + Y +++++ SGD T+ + Sbjct: 439 KIVMTLKGHEQDIYSLDYFPSGNKLVSGSGDRTVRI 474
>PWP2_CAEEL (P91341) Periodic tryptophan protein 2 homolog| Length = 910 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 5/124 (4%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 +A+G + G +K+W++R C TF H ++ + + IL+ S DGT+ + L+ Sbjct: 375 MATGAEDGKVKIWNSRSSFCTVTFDEHTSGVTAVKWTQSGRAILSASLDGTVRAHDLKRY 434 Query: 435 RVKSQSEFSE-DELLSLVIMKNGQKVVCGTPSGALLLYSW----GHFKDCSDRFLGHAQS 599 R E +L +L + K G V+ G +Y W GH D GH + Sbjct: 435 RNFRTLVCPEPTQLATLAVDKAGDLVIAGAKE-VFNIYIWSFETGHLLDI---LSGHESA 490 Query: 600 VDNL 611 + ++ Sbjct: 491 ISSI 494
>WD51B_PONPY (Q5RD06) WD-repeat protein 51B| Length = 451 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/161 (21%), Positives = 65/161 (40%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 L++ H R +F G +I++ S D +I D + + D+ G A Sbjct: 137 LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNP 196 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + T +AS +KVWD R + H ++ +++ + ++ S DGTL + Sbjct: 197 SGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSDNYLVTASSDGTLKILD 256 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 L R+ + + ++ K G+ G +LL+ Sbjct: 257 LLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
>COPB2_DROME (O62621) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| Length = 914 Score = 45.8 bits (107), Expect = 1e-04 Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 4/173 (2%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VCLTETTVASGDD 272 R+ RFV ILTGS DM I + T + + +AH D + + V T+ V + D Sbjct: 61 RSARFVARKNWILTGSDDMQIRVFNYNTLEKVHSF-EAHSDYLRCIAVHPTQPLVLTSSD 119 Query: 273 AGCIKVWD-TRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG-DGTLSVNSLRGNRVKS 446 IK+W+ + +C F H Y+ + + + A++ D T+ V L N Sbjct: 120 DMLIKLWNWEKMWACQRVFEGHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLGSNFANF 179 Query: 447 QSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGH-FKDCSDRFLGHAQSV 602 E E + + G K + + L+ W + K C GHAQ++ Sbjct: 180 TLEGHEKGVNCVDYYHGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNI 232 Score = 40.4 bits (93), Expect = 0.005 Identities = 21/94 (22%), Positives = 44/94 (46%) Frame = +3 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG D +K+WD + ++C T H IS + + +L S DGT+ + R+ Sbjct: 204 SGADDRLVKIWDYQNKTCVQTLEGHAQNISAVCFHPELPIVLTGSEDGTVRIWHSGTYRL 263 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL 542 ++ + + + ++ M+ V G G++++ Sbjct: 264 ETCLNYGFERVWTISSMRGTNNVALGYDEGSIII 297
>PRP46_CRYNE (Q5KDR4) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 473 Score = 45.4 bits (106), Expect = 1e-04 Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 4/195 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + R + D + + + D + D+ET KVI + V T + Sbjct: 223 HISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLV 282 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 +G ++VWD R R+ T H + D+ QI++ S D T+ + L + Sbjct: 283 TGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAAGKC 342 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSW----GHFKDCSDRFLGHAQSVDN 608 + + + +L I + SG + W G F + F+GH +++ N Sbjct: 343 MNTLTHHKKSVRALAIHPT-EYSFASASSGGNNIKKWKCPEGIF---VNNFVGH-EAIIN 397 Query: 609 LLKLDEETLISAAAD 653 L ++ E ++ + AD Sbjct: 398 TLSINSENVLFSGAD 412
>COPB2_RAT (O35142) Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)| (p102) Length = 904 Score = 45.4 bits (106), Expect = 1e-04 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 4/173 (2%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VCLTETTVASGDD 272 RA +FV ++TG+ DM I + T + + + +AH D I + V T+ + + D Sbjct: 60 RAAKFVARKNWVVTGADDMQIRVFNYNTLERV-HMFEAHSDYIRCIAVHPTQPFILTSSD 118 Query: 273 AGCIKVWD-TRQRSCCNTFHRHEDYISDMTY-VAGSDQILATSGDGTLSVNSLRGNRVKS 446 IK+WD ++ SC F H Y+ + ++Q + S D T+ V L + Sbjct: 119 DMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNF 178 Query: 447 QSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGH-FKDCSDRFLGHAQSV 602 E E + + G K + + L+ W + K C GHAQ+V Sbjct: 179 TLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTPEGHAQNV 231 Score = 40.8 bits (94), Expect = 0.004 Identities = 21/94 (22%), Positives = 43/94 (45%) Frame = +3 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG D +K+WD + ++C T H +S T+ I+ S DGT+ + R+ Sbjct: 203 SGADDRLVKIWDYQNKTCVQTPEGHAQNVSCATFHPELPIIITGSEDGTVRIWHSSTYRL 262 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL 542 +S + + + + ++ V G G++++ Sbjct: 263 ESTLNYGMERVWCVASLRGSNNVALGYDEGSIIV 296 Score = 37.0 bits (84), Expect = 0.051 Identities = 33/129 (25%), Positives = 54/129 (41%), Gaps = 2/129 (1%) Frame = +3 Query: 18 ELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIAR 197 ++ +F Y LER+ + H D R + + ILT S DM I D + ++ Sbjct: 79 QIRVFNYNT---LERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQ 135 Query: 198 LDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAG 371 + + H + ++V + AS IKVW S T HE ++ + Y +G Sbjct: 136 VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSG 195 Query: 372 SDQILATSG 398 D+ SG Sbjct: 196 GDKPYLISG 204
>WDR57_MOUSE (Q6PE01) WD-repeat protein 57| Length = 358 Score = 45.1 bits (105), Expect = 2e-04 Identities = 55/250 (22%), Positives = 92/250 (36%), Gaps = 57/250 (22%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAIN--------- 227 K H + + + G+++ + S D ++ D ETG+ + RL H +N Sbjct: 107 KGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLK-GHTSFVNSCYPARRGP 165 Query: 228 RLVCL----------------------------------TETTVASGDDAGCIKVWDTRQ 305 +LVC T + SG IKVWD RQ Sbjct: 166 QLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQ 225 Query: 306 RSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQS--------EFS 461 T H D ++ ++ + +L+ + D T+ V +R K + Sbjct: 226 NKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNF 285 Query: 462 EDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFL-----GHAQSVDNL-LKLD 623 E LL +G K+ G S +Y W D + R + GHA S++ + D Sbjct: 286 EKNLLRCSWSPDGSKIAAG--SADRFVYVW----DTTSRRVLYKLPGHAGSINEVAFHPD 339 Query: 624 EETLISAAAD 653 E ++SA++D Sbjct: 340 EPIILSASSD 349
>SCAP_CRIGR (P97260) Sterol regulatory element-binding protein| cleavage-activating protein (SREBP cleavage-activating protein) (SCAP) Length = 1276 Score = 45.1 bits (105), Expect = 2e-04 Identities = 48/187 (25%), Positives = 82/187 (43%), Gaps = 7/187 (3%) Frame = +3 Query: 6 LITGE----LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDV 173 L+TG L +FR D L F + H + V ++D V+ +G D +I DV Sbjct: 1089 LVTGSQDHTLRVFRLEDSCCL---FTLQGHSGAITTV-YIDQTMVLASGGQDGAICLWDV 1144 Query: 174 ETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISD 353 TG ++ GD + L C T ++SG D I +WD + + + +D Sbjct: 1145 LTGSRVSHTFAHRGD-VTSLTCTTSCVISSGLD-DLINIWD--RSTGIKLYSIQQDLGCG 1200 Query: 354 MTYVAGSDQILATSGDGTLSVNSLR-GNRVKS--QSEFSEDELLSLVIMKNGQKVVCGTP 524 + SD +L T G G +S L G+ +++ + SE + +++ + +VC Sbjct: 1201 ASLGVISDNLLVTGGQGCVSFWDLNYGDLLQTVYLGKNSEAQPARQILVLDNAAIVCNFG 1260 Query: 525 SGALLLY 545 S L+Y Sbjct: 1261 SELSLVY 1267
>WDR1_MOUSE (O88342) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 605 Score = 45.1 bits (105), Expect = 2e-04 Identities = 54/221 (24%), Positives = 88/221 (39%), Gaps = 15/221 (6%) Frame = +3 Query: 36 YADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDD--A 209 + +G P + F H VRF G T SAD I D +TG+ + L + A Sbjct: 172 FFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKA 231 Query: 210 HGDAINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSD 377 H I + ++T ASGD K+WD S +TF + + + + D Sbjct: 232 HDGGIYAISWSPDSTHLLSASGDKTS--KIWDVNVNSVVSTFPMGSNVLDQQLGCLWQKD 289 Query: 378 QILATSGDGTLSVNSLRGNR-------VKSQSEFSEDELLSLVIMKNGQK--VVCGTPSG 530 +L+ S G +N L N +K S+ + L + +NG K + G+ G Sbjct: 290 HLLSISLSG--YINYLDKNNPSKPLRVIKGHSK----SIQCLTVHRNGGKSYIYSGSHDG 343 Query: 531 ALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 + + ++ S GH V + + E L+S + D Sbjct: 344 HINYWDSETGENDSFSGKGHTNQVSRMTVNESEQLVSCSMD 384
>SIF2_YEAST (P38262) SIR4-interacting protein SIF2| Length = 535 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 3/176 (1%) Frame = +3 Query: 102 VRFVDSGTVILTGSADMSIVASDVE---TGKVIARLDDAHGDAINRLVCLTETTVASGDD 272 V +VD ++ G V E TGK+I HG T + S D Sbjct: 324 VEWVDDDKFVIPGPKGAIFVYQITEKTPTGKLIGH----HGPISVLEFNDTNKLLLSASD 379 Query: 273 AGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQS 452 G +++W + N F+ H I ++V G D++++ S DG++ + SL+ N + + S Sbjct: 380 DGTLRIWHGGNGNSQNCFYGHSQSIVSASWV-GDDKVISCSMDGSVRLWSLKQNTLLALS 438 Query: 453 EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKL 620 + + I ++GQK G + +Y S G+ + N L + Sbjct: 439 IVDGVPIFAGRISQDGQKYAVAFMDGQVNVYDLKKLNSKSRSLYGNRDGILNPLPI 494
>COPB2_CAEEL (Q20168) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 1000 Score = 44.7 bits (104), Expect = 2e-04 Identities = 47/191 (24%), Positives = 82/191 (42%), Gaps = 5/191 (2%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC-LTETTVASGDD 272 RA +FV + ++TGS DM I + T + + + +AH D + LV T V S D Sbjct: 61 RAAKFVPRKSWVVTGSDDMHIRVFNYNTLERVHQF-EAHSDYLRSLVVHPTLPYVISSSD 119 Query: 273 AGCIKVWDTRQR-SCCNTFHRHEDYISDMTYVAGSDQILATSG-DGTLSVNSLRGNRVKS 446 +K+WD + + +F H Y+ + + AT+ D T+ V N Sbjct: 120 DMLVKMWDWDNKWAMKQSFEGHTHYVMQIAINPKDNNTFATASLDKTVKVWQFGSNVPNF 179 Query: 447 QSEFSEDELLSLVIMKNGQK--VVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKL 620 E E + + G+K ++ G + ++ + + K C GHAQ+V ++ Sbjct: 180 TLEGHEKGVNCVDYYHGGEKPYIISGADDHLVKIWDYQN-KTCVQTLDGHAQNVSSVCFH 238 Query: 621 DEETLISAAAD 653 E LI ++ Sbjct: 239 PELPLIITGSE 249 Score = 36.2 bits (82), Expect = 0.088 Identities = 19/96 (19%), Positives = 39/96 (40%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 + SG D +K+WD + ++C T H +S + + I+ S D T+ + Sbjct: 202 IISGADDHLVKIWDYQNKTCVQTLDGHAQNVSSVCFHPELPLIITGSEDSTVRLWHANTY 261 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLL 542 R + + + + + K + G G++ L Sbjct: 262 RQEHTLNYGLERVWCIQAQKGANTIAIGYDEGSVTL 297
>GBB4_HUMAN (Q9HAV0) Guanine nucleotide-binding protein beta subunit 4| (Transducin beta chain 4) Length = 339 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/174 (24%), Positives = 67/174 (38%), Gaps = 7/174 (4%) Frame = +3 Query: 60 RLFAEKP-HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 R+ E P H RF+D ++ T S D + D+ET + GD ++ + Sbjct: 133 RVSRELPGHTGYLSCCRFLDDSQIV-TSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSL 191 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 T SG K+WD R C +F H I+ +++ S D T + Sbjct: 192 SPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRL 251 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCG------TPSGALLLYSWGHF 560 LR ++ ELL + + ++CG + SG LLL + F Sbjct: 252 FDLR----------ADQELL----LYSHDNIICGITSVAFSKSGRLLLAGYDDF 291
>FBXW7_DROME (Q9VZF4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein 7)| (Protein archipelago) Length = 1326 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/179 (24%), Positives = 76/179 (42%) Frame = +3 Query: 117 SGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWD 296 SG +I++GS D ++ D+++G + L H + R + L + V SG ++VWD Sbjct: 1044 SGNIIISGSTDRTLKVWDMDSGACVHTLQ-GHTSTV-RCMHLHGSKVVSGSRDATLRVWD 1101 Query: 297 TRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELL 476 Q SC + H + + Y D L SG V R + Sbjct: 1102 IEQGSCLHVLVGHLAAVRCVQY----DGKLIVSGAYDYMVKIWHPERQECLHTLQGHTNR 1157 Query: 477 SLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 + +G VV G+ ++ ++ +C +GH QS+ + ++L + L+S AD Sbjct: 1158 VYSLQFDGLHVVSGSLDTSIRVWD-VETGNCKHTLMGH-QSLTSGMELRQNILVSGNAD 1214 Score = 38.5 bits (88), Expect = 0.018 Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 4/161 (2%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E L + H + +++F G +++GS D SI DVETG L ++ + Sbjct: 1146 ECLHTLQGHTNRVYSLQF--DGLHVVSGSLDTSIRVWDVETGNCKHTL--MGHQSLTSGM 1201 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG-DGTLS 413 L + + SG+ +KVWD C T + S +T + + + + TS DGT+ Sbjct: 1202 ELRQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVK 1261 Query: 414 VNSLR-GNRVKSQSEFSEDELLSLV--IMKNGQKVVCGTPS 527 + ++ G+ +++ +V I N K++C S Sbjct: 1262 LWDVKTGDFIRNLVALDSGGSGGVVWRIRANDTKLICAVGS 1302 Score = 30.0 bits (66), Expect = 6.3 Identities = 34/150 (22%), Positives = 57/150 (38%), Gaps = 2/150 (1%) Frame = +3 Query: 210 HGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILA 389 H D + + + + SG D +KVW C T H + + + I++ Sbjct: 993 HDDHVITCLQFSGNRIVSGSDDNTLKVWSAVNGKCLRTLVGHTGGV--WSSQMSGNIIIS 1050 Query: 390 TSGDGTLSVNSLRGNRV--KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFK 563 S D TL V + Q S + L +G KVV G+ L ++ Sbjct: 1051 GSTDRTLKVWDMDSGACVHTLQGHTSTVRCMHL----HGSKVVSGSRDATLRVWDIEQ-G 1105 Query: 564 DCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 C +GH +V ++ D + ++S A D Sbjct: 1106 SCLHVLVGHLAAV-RCVQYDGKLIVSGAYD 1134
>UTP15_PONPY (Q5REE0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/172 (25%), Positives = 70/172 (40%), Gaps = 4/172 (2%) Frame = +3 Query: 84 KDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-VA 260 KD+ F G +I+ GS D + D+ +G+ R + H A++ + + V Sbjct: 80 KDTAYCATFRQDGRLIVAGSEDGGVQLFDI-SGRAPLRQFEGHTKAVHTVDFTADKYHVV 138 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG D +K+WD TF H DY+ D + S D T+ + R + Sbjct: 139 SGADDYTVKLWDIPNSKEVLTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSE 198 Query: 438 VKSQSEFSEDELLSLVIMKNGQKV--VCGTPSGALLLYSWGHFKDCSDRFLG 587 S++ +++GQ V V PSG LL+ + G + D G Sbjct: 199 -------------SVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVCDMLKG 237
>UTP15_MOUSE (Q8C7V3) U3 small nucleolar RNA-associated protein 15 homolog| (Src-associated protein SAW) Length = 528 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 4/172 (2%) Frame = +3 Query: 84 KDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-VA 260 KD+ F G +++ GS D + D+ G+ R + H A++ + + V Sbjct: 80 KDTAYCATFRQDGQLLVAGSEDGVVQLFDIN-GRAPLRQFEGHTKAVHTVDFTADNYHVV 138 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG D +K+WD TF H DY+ D + S D T+ + R N+ Sbjct: 139 SGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKIFDARTNK 198 Query: 438 VKSQSEFSEDELLSLVIMKNGQKV--VCGTPSGALLLYSWGHFKDCSDRFLG 587 +++ +++GQ V V PSG LL+ + G + D G Sbjct: 199 -------------NVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKG 237
>KTNB1_STRPU (O61585) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 690 Score = 44.3 bits (103), Expect = 3e-04 Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 4/116 (3%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT----E 248 H +V+F S +++ GS ++ D+E K++ L N + C+ Sbjct: 58 HTSPVDSVKFNSSEELVVAGSQSGTMKIYDLEPAKIVRTLTGHR----NSIRCMDFHPFG 113 Query: 249 TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 VASG +K+WD R++ C T+ H D ++ + + ++ S D T+ + Sbjct: 114 EFVASGSTDTNVKLWDVRRKGCIYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKL 169 Score = 34.7 bits (78), Expect = 0.25 Identities = 19/78 (24%), Positives = 32/78 (41%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 ++ K H D ++F G ++T S D +I D+ GK+ + G Sbjct: 136 IYTYKGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMGKLFQEFKNHTGGVTGIEFHP 195 Query: 243 TETTVASGDDAGCIKVWD 296 E +ASG ++ WD Sbjct: 196 NEFLLASGSSDRTVQFWD 213 Score = 34.7 bits (78), Expect = 0.25 Identities = 28/153 (18%), Positives = 66/153 (43%), Gaps = 4/153 (2%) Frame = +3 Query: 207 AHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ 380 AH +N L ++ + +G + + +W +++C + H + + + + + Sbjct: 14 AHSSNVNCLALGPMSGRVMVTGGEDKKVNLWAVGKQNCIISLSGHTSPVDSVKFNSSEEL 73 Query: 381 ILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 ++A S GT+ + L ++ + + + G+ V G+ + L+ Sbjct: 74 VVAGSQSGTMKIYDLEPAKIVRTLTGHRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRR- 132 Query: 561 KDCSDRFLGHAQSVDNLLKL--DEETLISAAAD 653 K C + GH+ V N++K D + L++A+ D Sbjct: 133 KGCIYTYKGHSDQV-NMIKFSPDGKWLVTASED 164
>EMAL_CAEEL (O45487) Echinoderm microtubule-associated protein-like elp-1| Length = 891 Score = 44.3 bits (103), Expect = 3e-04 Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 6/180 (3%) Frame = +3 Query: 126 VILTGSADMSIVASDVETG---KVIARLDDAHGDAINRLVCLTETT-VASGDDAGCIKVW 293 ++L G S D TG K +A + +C E V +GD G I +W Sbjct: 468 IVLYGKGHFSFFNYDPATGVLVKTVATFEGRDKPKTVLSMCFGENDQVVTGDSNGTISIW 527 Query: 294 DTRQRSCCNTFHR-HEDYISDMTYVAGSDQILATSGDGTLSVNSLRG-NRVKSQSEFSED 467 D R H H + +T +A S +IL+ D +S L+ R + E ++ Sbjct: 528 DPRTCKTTKQAHSVHPGGVYSLT-LAKSGKILSGGKDRMVSEWDLQDLVRTRRPIELPDE 586 Query: 468 ELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAA 647 + VI++NG +++ GT S LL + + + + G ++ LL LI+++ Sbjct: 587 KGFPRVILQNGSELIIGTSSNTLLFGNIENSTNLTSLIEGDPGNLTFLLTCSSNQLITSS 646
>KTNB1_ARATH (Q8H0T9) Katanin p80 WD40-containing subunit B1 homolog 1| Length = 837 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/134 (20%), Positives = 59/134 (44%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H +V F S ++ G+A +I D+E K++ L + I+ A Sbjct: 58 HSSGIDSVTFDASEVLVAAGAASGTIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFA 117 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG +K+WD R++ C +T+ H ++ + + +++ D + V L ++ Sbjct: 118 SGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKL 177 Query: 441 KSQSEFSEDELLSL 482 ++ + E ++ SL Sbjct: 178 LTEFKSHEGQIQSL 191 Score = 40.0 bits (92), Expect = 0.006 Identities = 36/158 (22%), Positives = 59/158 (37%), Gaps = 1/158 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-V 257 H+ +C +V F G +GS D ++ D+ K H +N L + V Sbjct: 100 HRSNCISVDFHPFGEFFASGSLDTNLKIWDIRK-KGCIHTYKGHTRGVNVLRFTPDGRWV 158 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG + +KVWD F HE I + + + S D T+ L Sbjct: 159 VSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLETFE 218 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSW 551 + + L +G+ V+CG +L ++SW Sbjct: 219 LIGSGGPETAGVRCLSFNPDGKTVLCGLQE-SLKIFSW 255 Score = 30.0 bits (66), Expect = 6.3 Identities = 17/74 (22%), Positives = 29/74 (39%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H +RF G +++G D + D+ GK++ G + E Sbjct: 140 KGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFL 199 Query: 255 VASGDDAGCIKVWD 296 +A+G +K WD Sbjct: 200 LATGSADRTVKFWD 213
>YZLL_CAEEL (Q93847) Hypothetical WD-repeat protein K04G11.4| Length = 395 Score = 43.9 bits (102), Expect = 4e-04 Identities = 40/168 (23%), Positives = 69/168 (41%), Gaps = 3/168 (1%) Frame = +3 Query: 51 PLERLFAEKP--HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAI 224 P +L AE P HK S ++F G + +GSAD SI ++ V + H I Sbjct: 94 PTYKLVAEIPNAHKKSISGIKFSPDGRYMGSGSADCSIKIWRMDF--VYEKTLMGHRLGI 151 Query: 225 NRLVCLTET-TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGD 401 N +++ + S D +KV+D C T H +Y+ + I + S D Sbjct: 152 NEFSWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFD 211 Query: 402 GTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 T+ + R ED + S+ ++G + G+ G + ++ Sbjct: 212 ETIRIWCARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIW 259 Score = 38.1 bits (87), Expect = 0.023 Identities = 32/159 (20%), Positives = 66/159 (41%), Gaps = 1/159 (0%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQ 305 +I++ S D + DV +G+ + L + T +ASG I++W R Sbjct: 162 LIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARN 221 Query: 306 RSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV-NSLRGNRVKSQSEFSEDELLSL 482 + + HED +S + + + + S DG + + +S G VK+ + + + Sbjct: 222 GNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHV 281 Query: 483 VIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQS 599 NG+ ++ + L L+ + + + + GH S Sbjct: 282 KFSPNGKYILASNLNNTLKLWDYQKLRVLKE-YTGHENS 319
>PRL2_ARATH (Q39190) PP1/PP2A phosphatases pleiotropic regulator PRL2| Length = 479 Score = 43.5 bits (101), Expect = 5e-04 Identities = 44/192 (22%), Positives = 75/192 (39%), Gaps = 1/192 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H R+V F S TGSAD +I DV TG + L G V T + Sbjct: 169 HLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMF 228 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 S D +K WD Q ++H H + + D +L D V +R ++ Sbjct: 229 SAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIR-TKM 287 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL-LK 617 + + ++ S++ +V+ G+ + + + K + H ++V + L Sbjct: 288 QIFVLPHDSDVFSVLARPTDPQVITGSHDSTIKFWDLRYGKSMA-TITNHKKTVRAMALH 346 Query: 618 LDEETLISAAAD 653 E +SA+AD Sbjct: 347 PKENDFVSASAD 358
>SPG16_MOUSE (Q8K450) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 639 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 4/128 (3%) Frame = +3 Query: 45 GLPLER-LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDA 221 GLP L H D F SG+ + T S D +I D+ G+ L+ H A Sbjct: 388 GLPQGNVLLTGSGHTDWLSGCCFHPSGSKLATSSGDSTIKLWDLNKGECTLTLE-GHNHA 446 Query: 222 INRLVCLTETT---VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT 392 + C + VAS K+WD C T + H D ++ + + S+ +L Sbjct: 447 V--WSCTWHSCGDFVASASLDMTSKIWDVNSERCRYTLYGHTDSVNSIEFFPFSNILLTA 504 Query: 393 SGDGTLSV 416 S D TLSV Sbjct: 505 SADKTLSV 512 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H DS ++ F ++LT SAD ++ D TGK L H ++N + Sbjct: 485 HTDSVNSIEFFPFSNILLTASADKTLSVWDARTGKCEQSL-YGHMHSVNDATFTPRGHII 543 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 AS D G K+WD R+ + +++ + + S +G + + L+ + Sbjct: 544 ASCDARGVTKLWDFRKLIPIVSIDVGPSSGNEVNFDQSGRVLAQASANGIIHLLDLKSGQ 603 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 + + E E+ S+V G+ + G G + L+ Sbjct: 604 I-HKLVGHESEVHSVVFSHLGENLYSGGSDGTIRLW 638
>GBB_SCHPO (Q10282) Guanine nucleotide-binding protein beta subunit| Length = 305 Score = 43.5 bits (101), Expect = 5e-04 Identities = 36/144 (25%), Positives = 62/144 (43%), Gaps = 3/144 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINR--LVCLTETT 254 H ++VD G +LTGS D + + D+E K I+ L D ++ L Sbjct: 105 HAGFVSCCKYVDDGH-LLTGSGDKTCMFWDIEQAKAISVLKGHEMDIVSLDFLPSNPNLF 163 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V G D K+WD R CC TF + I+ +++ + + + DG +R + Sbjct: 164 VTGGCDK-LAKLWDLRAAYCCATFPGNTSDINSISFFPSNADFVTGAEDGIARCFDIRAS 222 Query: 435 -RVKSQSEFSEDELLSLVIMKNGQ 503 + S S + S++ K+G+ Sbjct: 223 AEIFQYSSPSSSPINSVLFSKSGK 246
>LUB1_SCHPO (O94289) Ubiquitin homeostasis protein lub1| Length = 713 Score = 43.5 bits (101), Expect = 5e-04 Identities = 39/158 (24%), Positives = 68/158 (43%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H+ S AV + + +TGSAD I + G+ + + AH D + R +C Sbjct: 134 KGHQSSVWAVLALGED-IFITGSADKLI---KIWNGEKLVKSILAHNDCV-RSLCQIPGG 188 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 AS + G IK+W T H H ++ +TY+ I + D T+ + +G Sbjct: 189 FASCSNDGVIKLW-TSDGEFLYELHGHTSFVYSLTYIHNQQLIASCGEDRTIRI--WKGK 245 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 + S+ + NG +VCG+ G + +++ Sbjct: 246 ECLQCITLPTTSVWSVSSLPNGD-LVCGSSDGFVRIFT 282
>TUP1_YEAST (P16649) Glucose repression regulatory protein TUP1 (Flocculation| suppressor protein) (Repressor AER2) Length = 713 Score = 43.1 bits (100), Expect = 7e-04 Identities = 41/186 (22%), Positives = 77/186 (41%), Gaps = 13/186 (6%) Frame = +3 Query: 27 MFRYADGLPLERLF---AEKPHKDSC---RAVRFVDSGTVILTGSADMSIVA--SDVETG 182 ++R +DG + RL A H++S D+ T+ T + ++ A S E Sbjct: 369 VYRVSDGSLVARLSDDSAANNHRNSITENNTTTSTDNNTMTTTTTTTITTTAMTSAAELA 428 Query: 183 KVIARLDDAHG---DAINRLVCLTETT--VASGDDAGCIKVWDTRQRSCCNTFHRHEDYI 347 K + L+ + D R VC + +A+G + I++WD R HE I Sbjct: 429 KDVENLNTSSSPSSDLYIRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDI 488 Query: 348 SDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPS 527 + Y D++++ SGD T+ + LR + + V +G+ + G+ Sbjct: 489 YSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLD 548 Query: 528 GALLLY 545 A+ ++ Sbjct: 549 RAVRVW 554 Score = 37.4 bits (85), Expect = 0.039 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 20/125 (16%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDD------AHGDAINRLVCLTE-TTVASGDDAG 278 G I GS D ++ D ETG ++ RLD H D++ +V + +V SG Sbjct: 539 GKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDR 598 Query: 279 CIKVWDTRQR------------SCCNTFHRHEDYISDMTYVAGSDQILATSGD-GTLSVN 419 +K+W+ + +C T+ H+D++ + + IL+ S D G L + Sbjct: 599 SVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWD 658 Query: 420 SLRGN 434 GN Sbjct: 659 KKSGN 663
>WD51A_BOVIN (Q2TBP4) WD-repeat protein 51A| Length = 407 Score = 43.1 bits (100), Expect = 7e-04 Identities = 32/158 (20%), Positives = 62/158 (39%), Gaps = 4/158 (2%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 + H + R+V F G +T S D ++ K + L IN + C + Sbjct: 100 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTHRQKFLFSLSQH----INWVRCAKFSP 155 Query: 255 ----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + S D +K+WD R C +++ H +++ + + I A D T+ V Sbjct: 156 DGRLIVSASDDKTVKLWDKTSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGAL 536 +R +R+ + + +L +G +V + L Sbjct: 216 VRTHRLLQHYQLHSAAVNALSFHPSGNYLVTASSDSTL 253 Score = 39.3 bits (90), Expect = 0.010 Identities = 27/127 (21%), Positives = 54/127 (42%), Gaps = 1/127 (0%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VC 239 LF+ H + R +F G +I++ S D ++ D +T + HG + + Sbjct: 138 LFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KTSRECVHSYCEHGGFVTYVDFH 196 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVN 419 + T +A+ +KVWD R + H ++ +++ + ++ S D TL + Sbjct: 197 PSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNALSFHPSGNYLVTASSDSTLKIL 256 Query: 420 SLRGNRV 440 L R+ Sbjct: 257 DLMEGRL 263 Score = 32.0 bits (71), Expect = 1.7 Identities = 19/71 (26%), Positives = 31/71 (43%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A+ F SG ++T S+D ++ D+ G+++ L G A T A Sbjct: 228 HSAAVNALSFHPSGNYLVTASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287 Query: 261 SGDDAGCIKVW 293 SG + VW Sbjct: 288 SGGSDEQVMVW 298
>NLE1_BOVIN (Q58D20) Notchless homolog 1| Length = 485 Score = 43.1 bits (100), Expect = 7e-04 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 129 ILTGSADMSIVA-SDVETGKVIARLDDAHGDAINRLVCLTETTV-ASGDDAGCIKVWDTR 302 +++GS D ++ S E K +AR+ H IN++V ++ V AS IK+WD R Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLARMT-GHQALINQVVFSPDSRVIASASFDKSIKLWDGR 402 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSL 482 + H + + + A S +++ S D TL V ++ ++ + DE+ ++ Sbjct: 403 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAV 462 Query: 483 VIMKNGQKVVCGTPSGALLLY 545 +GQ+V G L ++ Sbjct: 463 DWSPDGQRVASGGKDKCLRIW 483 Score = 36.6 bits (83), Expect = 0.067 Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 6/180 (3%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 + + S D S+ D G+ L H ++ L + + S IKVW Sbjct: 219 VASSSKDGSVRVWDTTAGRCERTLT-GHAQSVTCLRWGGDGLLYSASQDRTIKVWRAHDG 277 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATS----GDGTLSVNSLRGNRVKSQSEFSEDEL- 473 C T H +++ T +D L T + +++ LRG S E E L Sbjct: 278 VLCRTLQGHGHWVN--TMALSTDYALRTGAFEPAEASVNAQDLRG----SLQELKERALS 331 Query: 474 -LSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAA 650 +LV + +++V G+ L L+S K R GH ++ ++ + +I++A+ Sbjct: 332 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASAS 391 Score = 35.0 bits (79), Expect = 0.20 Identities = 29/123 (23%), Positives = 48/123 (39%), Gaps = 6/123 (4%) Frame = +3 Query: 66 FAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT 245 F + H+ ++ + G + +G + I+ D TGK + R H I L Sbjct: 150 FTCQGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEP 209 Query: 246 ETT------VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 VAS G ++VWDT C T H ++ + + G + + S D T Sbjct: 210 LHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRW-GGDGLLYSASQDRT 268 Query: 408 LSV 416 + V Sbjct: 269 IKV 271
>WD51B_MOUSE (Q8BHD1) WD-repeat protein 51B| Length = 476 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/161 (19%), Positives = 66/161 (40%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 L++ H R +F G +I++ S D +I D + + D+ G A Sbjct: 137 LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNP 196 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 T +AS +K+WD R + H ++ +++ + ++ S DGT+ + Sbjct: 197 NGTCIASAGSDHAVKIWDIRMNKLLQHYQVHSCGVNCLSFHPLGNSLVTASSDGTVKMLD 256 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 L R+ + + ++ K+G+ + G +L++ Sbjct: 257 LIEGRLIYTLQGHTGPVFTVSFSKDGELLTSGGADAQVLIW 297
>YK16_YEAST (P36130) Hypothetical 74.7 kDa Trp-Asp repeats-containing protein| in DAL80-GAP1 intergenic region Length = 659 Score = 43.1 bits (100), Expect = 7e-04 Identities = 36/143 (25%), Positives = 61/143 (42%), Gaps = 23/143 (16%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLD----DAHGD------AINR 230 HKD A+ F +++GS D I D+ TGK I +LD H D ++N Sbjct: 439 HKDEITALSF--DSEALVSGSRDKKIFHWDLTTGKCIQQLDLIFTPTHSDIKMPARSLNN 496 Query: 231 LVCLTET-------------TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAG 371 CL T +A+G G +++WD R H D I+ + + Sbjct: 497 GACLLGTEAPMIGALQCYNSALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKF--D 554 Query: 372 SDQILATSGDGTLSVNSLRGNRV 440 S++++ S D ++ + LR + + Sbjct: 555 SEKLVTGSMDNSVRIWDLRTSSI 577
>UTP15_HUMAN (Q8TED0) U3 small nucleolar RNA-associated protein 15 homolog| Length = 518 Score = 43.1 bits (100), Expect = 7e-04 Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 4/172 (2%) Frame = +3 Query: 84 KDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-VA 260 KD+ F G +++ GS D + D+ +G+ R + H A++ + + V Sbjct: 80 KDTAYCATFRQDGRLLVAGSEDGGVQLFDI-SGRAPLRQFEGHTKAVHTVDSTADKYHVV 138 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG D +K+WD TF H DY+ D + S D T+ + R + Sbjct: 139 SGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSE 198 Query: 438 VKSQSEFSEDELLSLVIMKNGQKV--VCGTPSGALLLYSWGHFKDCSDRFLG 587 S++ +++GQ V V PSG LL+ + G + D G Sbjct: 199 -------------SVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKG 237
>CWF17_SCHPO (O94620) Cell cycle control protein cwf17| Length = 340 Score = 43.1 bits (100), Expect = 7e-04 Identities = 46/224 (20%), Positives = 92/224 (41%), Gaps = 10/224 (4%) Frame = +3 Query: 12 TGELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTG-SADMSIVASDVETGKV 188 + + H+ + D + +++ K H A+ + G+ +LT S D ++ D + Sbjct: 112 SSDTHLMSW-DAVSGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTMKVWDSRSKDC 170 Query: 189 IARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVA 368 I +++ + + T V G G IK+WD R C + H+D I+ + Sbjct: 171 IKTIEEKY-PLTAVAIAQQGTQVFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISK 229 Query: 369 GSDQILATSGDGTLSVNSLR--GNRVKSQSEF------SEDELLSLVIMKNGQKVVCGTP 524 +L+ S D T+ + ++ + + F E LL + +N + V G Sbjct: 230 DGSSLLSNSMDNTVRIFDVKPFASAQRQLQIFEGAIHGQEHNLLGVAWSRNSRFV--GAG 287 Query: 525 SGALLLYSWGHFKDCSDRFLGHAQSVDNL-LKLDEETLISAAAD 653 S +Y W D GH SV+++ ++ ++S ++D Sbjct: 288 SSDKNVYVWSATGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSD 331
>WDR57_PONPY (Q5RF51) WD-repeat protein 57| Length = 357 Score = 43.1 bits (100), Expect = 7e-04 Identities = 50/216 (23%), Positives = 86/216 (39%), Gaps = 13/216 (6%) Frame = +3 Query: 45 GLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAI 224 G ++RL +SC R ++ TGS D ++ D+ I + + + Sbjct: 141 GERVKRLKGHTSFVNSCYPAR--RGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTY-QVL 197 Query: 225 NRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDG 404 T + SG IKVWD RQ T H D ++ ++ + +L+ + D Sbjct: 198 AVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDN 257 Query: 405 TLSVNSLRGNRVKSQS--------EFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 T+ V +R K + E LL +G K+ G+ ++ ++ Sbjct: 258 TVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRSVCVWD---- 313 Query: 561 KDCSDRFL----GHAQSVDNL-LKLDEETLISAAAD 653 S R L GHA S++ + DE +ISA++D Sbjct: 314 -TTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
>GBB_MAIZE (P49178) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 8/135 (5%) Frame = +3 Query: 48 LPLERLFA-EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA----RLDDAH 212 +P+ R+ K + SC+ V D T ++T S D + V DV TG+ I+ H Sbjct: 147 MPVSRILTGHKGYVSSCQYVP--DQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGH 204 Query: 213 GDAINRLVCLTETT--VASGDDAGCIKVWDTRQRS-CCNTFHRHEDYISDMTYVAGSDQI 383 + + + T SG +++WD R S T+H HED ++ + + + Sbjct: 205 TADVQSVSINSSNTNMFVSGSCDTTVRLWDIRIASRAVRTYHGHEDDVNSVKFFPDGHRF 264 Query: 384 LATSGDGTLSVNSLR 428 S DGT + +R Sbjct: 265 GTGSDDGTCRLFDMR 279 Score = 30.0 bits (66), Expect = 6.3 Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 11/130 (8%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETG---KVIARLDDAHGDAINRLV----C 239 H+D +V+F G TGS D + D+ TG +V +R D + + + + Sbjct: 248 HEDDVNSVKFFPDGHRFGTGSDDGTCRLFDMRTGHQLQVYSREPDRNSNELPTVTSIAFS 307 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCC----NTFHRHEDYISDMTYVAGSDQILATSGDGT 407 ++ + +G G VWDT N + H+ IS + + + S D Sbjct: 308 ISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNSHDGRISCLGMSSDGSALCTGSWDKN 367 Query: 408 LSVNSLRGNR 437 L + + G+R Sbjct: 368 LKIWAFSGHR 377
>WDR37_MOUSE (Q8CBE3) WD-repeat protein 37| Length = 496 Score = 42.7 bits (99), Expect = 0.001 Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 2/148 (1%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H+ A ++ G ++T S D + DVET +++ L + + T+ Sbjct: 280 KSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRL 339 Query: 255 VASGDDAGCIKVWDTRQRS--CCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 V + ++WD R S N F H D ++ + G D +++ S D T+ V L+ Sbjct: 340 VVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVG-DNVVSGSDDRTVKVWDLK 398 Query: 429 GNRVKSQSEFSEDELLSLVIMKNGQKVV 512 R + D ++ + + GQK++ Sbjct: 399 NMR-SPIATIRTDSAINRINVCVGQKII 425
>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein| Length = 678 Score = 42.7 bits (99), Expect = 0.001 Identities = 48/189 (25%), Positives = 80/189 (42%), Gaps = 4/189 (2%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H + ++F D+ ++ TGS D +I D ETG+ + L H I R + +T Sbjct: 346 KGHTNGVMCLQFEDN--ILATGSYDTTIKIWDTETGEELRTL-RGHESGI-RCLQFDDTK 401 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRG 431 + SG IKVW+ R C +T+ H + + + A ILA+ S D T+ + + Sbjct: 402 LISGSMDRTIKVWNWRTGECISTYTGHRGGVIGLHFDA---SILASGSVDKTVKIWNF-- 456 Query: 432 NRVKSQSEFS---EDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSV 602 + +S FS + ++ V + + V + K C F GH V Sbjct: 457 ---EDKSTFSLRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDLDTKTCIRTFHGHVGQV 513 Query: 603 DNLLKLDEE 629 ++ L E Sbjct: 514 QQVVPLPRE 522 Score = 34.7 bits (78), Expect = 0.25 Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 13/106 (12%) Frame = +3 Query: 123 TVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VCLTETTVASGDDAGCIKVWDT 299 +++ +GS D ++ + E + H D +N + V + TV S D +++WD Sbjct: 440 SILASGSVDKTVKIWNFEDKSTFSLR--GHTDWVNAVRVDTSSRTVFSASDDCTVRLWDL 497 Query: 300 RQRSCCNTFHRHEDYISDMTYV------------AGSDQILATSGD 401 ++C TFH H + + + +D + TSGD Sbjct: 498 DTKTCIRTFHGHVGQVQQVVPLPREFEFEEHDAECENDDLSTTSGD 543
>CSTF1_PONPY (Q5R8K2) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 5/120 (4%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK--VIARLDDAHGDAINR 230 +R F + R++ F SG IL G+ ++ D+ T + V D H DAI Sbjct: 208 KRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHADAICS 267 Query: 231 LVCLTETTV-ASGDDAGCIKVWDTRQRSCCNTFHRHED--YISDMTYVAGSDQILATSGD 401 + + + +G GCIK+WD C TF + D + + S IL++ D Sbjct: 268 VNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKD 327 Score = 37.0 bits (84), Expect = 0.051 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 3/164 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK CR + G +I TGSAD SI D E +++A+ A+ V + ET Sbjct: 107 HKGPCRVATYSRDGQLIATGSADASIKILDTE--RMLAK------SAMPIEVMMNETAQQ 158 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNR 437 + ++ I+ T + H D ++ + + ++QILA+ S D TL + Sbjct: 159 NMENHPVIR-----------TLYDHVDEVTCLAF-HPTEQILASGSRDYTLKLFDYSKPS 206 Query: 438 VKSQSEFSEDE--LLSLVIMKNGQKVVCGTPSGALLLYSWGHFK 563 K ++ ++ L S+ +G ++ GT L LY F+ Sbjct: 207 AKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQ 250
>TUP11_SCHPO (Q09715) Transcriptional repressor tup11| Length = 614 Score = 42.4 bits (98), Expect = 0.001 Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 7/198 (3%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-- 254 H V+F ++G + TG + V DV+TGK + L + D L T Sbjct: 312 HPSVVCCVKFSNNGKYLATGCNQAANVF-DVQTGKKLFTLHEESPDPSRDLYVRTIAFSP 370 Query: 255 ----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + +G + IK+WD + F HE I + + I++ SGD T + Sbjct: 371 DGKYLVTGTEDRQIKLWDLSTQKVRYVFSGHEQDIYSLDFSHNGRFIVSGSGDRTARLWD 430 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSV 602 + + + E E+ + ++ I N Q + G S ++ W +R GH +SV Sbjct: 431 VETGQCILKLEI-ENGVTAIAISPNDQFIAVG--SLDQIIRVWSVSGTLVERLEGHKESV 487 Query: 603 DNL-LKLDEETLISAAAD 653 ++ D L+S + D Sbjct: 488 YSIAFSPDSSILLSGSLD 505 Score = 38.9 bits (89), Expect = 0.014 Identities = 29/119 (24%), Positives = 54/119 (45%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H+ ++ F +G I++GS D + DVETG+ I +L+ +G + + +A Sbjct: 401 HEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENG-VTAIAISPNDQFIA 459 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 G I+VW + H++ + + + S +L+ S D T+ V L+ R Sbjct: 460 VGSLDQIIRVWSV-SGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATR 517
>GBB_YEAST (P18851) Guanine nucleotide-binding protein beta subunit| Length = 423 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/126 (24%), Positives = 54/126 (42%), Gaps = 6/126 (4%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL---- 242 K H + F D+ ILT S DM+ D+ K + D GD + + Sbjct: 178 KGHTCYISDIEFTDNAH-ILTASGDMTCALWDIPKAKRVREYSDHLGDVLALAIPEEPNS 236 Query: 243 --TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + T AS G +WD+R S +F+ ++ I+ + + I+A S +G +++ Sbjct: 237 ENSSNTFASCGSDGYTYIWDSRSPSAVQSFYVNDSDINALRFFKDGMSIVAGSDNGAINM 296 Query: 417 NSLRGN 434 LR + Sbjct: 297 YDLRSD 302
>SPG16_HUMAN (Q8N0X2) Sperm-associated antigen 16 protein (PF20 protein homolog)| Length = 631 Score = 42.0 bits (97), Expect = 0.002 Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 3/115 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-- 254 H D F SG + T S D ++ D+ TG I + H A+ C + Sbjct: 393 HTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFE-GHSRAV--WSCTWHSCGN 449 Query: 255 -VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 VAS K+WD C T + H D ++ + + S+ +L +S D TLS+ Sbjct: 450 FVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSI 504 Score = 38.9 bits (89), Expect = 0.014 Identities = 34/157 (21%), Positives = 66/157 (42%), Gaps = 1/157 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTV 257 H DS ++ F +LT SAD ++ D TG + + H +IN + + Sbjct: 477 HTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTG-ICEQSLYGHMHSINDAIFDPRGHMI 535 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 AS D G K+WD R+ + +++ + + + SG+G + + L+ Sbjct: 536 ASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGVIHLLDLKSGE 595 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 + E+E ++V +G+ + G G + +S Sbjct: 596 IHKLMG-HENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
>WDR1_HUMAN (O75083) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| (NORI-1) Length = 605 Score = 42.0 bits (97), Expect = 0.002 Identities = 55/221 (24%), Positives = 85/221 (38%), Gaps = 15/221 (6%) Frame = +3 Query: 36 YADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL--DDA 209 + +G P + F H VRF G T SAD I D +TG+ + L A Sbjct: 172 FFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKA 231 Query: 210 HGDAINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSD 377 H I + ++T ASGD K+WD S +TF + + + D Sbjct: 232 HDGGIYAISWSPDSTHLLSASGDKTS--KIWDVSVNSVVSTFPMGSTVLDQQLGCLWQKD 289 Query: 378 QILATSGDGTLSVNSLRGNR-------VKSQSEFSEDELLSLVIMKNGQK--VVCGTPSG 530 +L+ S G +N L N +K S+ + L + KNG K + G+ G Sbjct: 290 HLLSVSLSG--YINYLDRNNPSKPLHVIKGHSK----SIQCLTVHKNGGKSYIYSGSHDG 343 Query: 531 ALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 + + ++ S GH V + + LIS + D Sbjct: 344 HINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLISCSMD 384
>CSTF1_HUMAN (Q05048) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 42.0 bits (97), Expect = 0.002 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 5/120 (4%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK--VIARLDDAHGDAINR 230 +R F + R++ F SG IL G+ ++ D+ T + V D H DAI Sbjct: 208 KRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICS 267 Query: 231 LVCLTETTV-ASGDDAGCIKVWDTRQRSCCNTFHRHED--YISDMTYVAGSDQILATSGD 401 + + + +G GCIK+WD C TF + D + + S IL++ D Sbjct: 268 VNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKD 327 Score = 37.0 bits (84), Expect = 0.051 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 3/164 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK CR + G +I TGSAD SI D E +++A+ A+ V + ET Sbjct: 107 HKGPCRVATYSRDGQLIATGSADASIKILDTE--RMLAK------SAMPIEVMMNETAQQ 158 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNR 437 + ++ I+ T + H D ++ + + ++QILA+ S D TL + Sbjct: 159 NMENHPVIR-----------TLYDHVDEVTCLAF-HPTEQILASGSRDYTLKLFDYSKPS 206 Query: 438 VKSQSEFSEDE--LLSLVIMKNGQKVVCGTPSGALLLYSWGHFK 563 K ++ ++ L S+ +G ++ GT L LY F+ Sbjct: 207 AKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQ 250
>PRP4_MOUSE (Q9DAW6) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 1/152 (0%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E + ++ H + F G++ TG D D+ TG+ I L+ + Sbjct: 355 EEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINF 414 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTY-VAGSDQILATSGDGTLS 413 +A+G KVWD RQR C T H++ ++ + + D +L + D T Sbjct: 415 SPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAK 474 Query: 414 VNSLRGNRVKSQSEFSEDELLSLVIMKNGQKV 509 + + G E +++ L I +GQ + Sbjct: 475 IWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 506
>NLE1_MOUSE (Q8VEJ4) Notchless homolog 1| Length = 484 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 2/141 (1%) Frame = +3 Query: 129 ILTGSADMSIVA-SDVETGKVIARLDDAHGDAINRLVCLTETT-VASGDDAGCIKVWDTR 302 +++GS D ++ S E K +AR+ H IN+++ ++ VAS IK+WD R Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLARMT-GHQALINQVLFSPDSRIVASASFDKSIKLWDGR 401 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSL 482 + H + + + A S +++ S D TL V ++ ++ + DE+ ++ Sbjct: 402 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAV 461 Query: 483 VIMKNGQKVVCGTPSGALLLY 545 +GQ+V G L ++ Sbjct: 462 DWSPDGQRVASGGKDKCLRIW 482 Score = 37.7 bits (86), Expect = 0.030 Identities = 37/178 (20%), Positives = 73/178 (41%), Gaps = 4/178 (2%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 + + S D S+ D G+ R+ H ++ L + + S IKVW Sbjct: 218 VASSSKDGSVRVWDTTAGRC-ERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDG 276 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATS----GDGTLSVNSLRGNRVKSQSEFSEDELL 476 C T H +++ T +D L T + T++ L+G+ + + S Sbjct: 277 VLCRTLQGHGHWVN--TMALSTDYALRTGAFEPAEATVNAQDLQGSLKELKERAS--SRY 332 Query: 477 SLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAA 650 +LV + +++V G+ L L+S K R GH ++ +L + ++++A+ Sbjct: 333 NLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASAS 390 Score = 31.2 bits (69), Expect = 2.8 Identities = 29/126 (23%), Positives = 47/126 (37%), Gaps = 9/126 (7%) Frame = +3 Query: 66 FAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV--- 236 F K H+ ++ + G + +G + I+ D TG + R H I L Sbjct: 149 FTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGLQVGRTLTGHSKWITGLSWEP 208 Query: 237 ------CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 C VAS G ++VWDT C H ++ + + G + + S Sbjct: 209 LHMNPEC---RYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQ 264 Query: 399 DGTLSV 416 D T+ V Sbjct: 265 DRTIKV 270
>WD51A_HUMAN (Q8NBT0) WD-repeat protein 51A| Length = 407 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/158 (19%), Positives = 61/158 (38%), Gaps = 4/158 (2%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 + H + R+V F G +T S D ++ K + L IN + C + Sbjct: 100 RAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQH----INWVRCAKFSP 155 Query: 255 ----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + S D +K+WD R C +++ H +++ + + I A D T+ V Sbjct: 156 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGAL 536 +R +R+ + + L +G ++ + L Sbjct: 216 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTL 253 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/126 (19%), Positives = 52/126 (41%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 LF+ H + R +F G +I++ S D ++ D + + + + G Sbjct: 138 LFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHP 197 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + T +A+ +KVWD R + H ++ +++ + ++ S D TL + Sbjct: 198 SGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILD 257 Query: 423 LRGNRV 440 L R+ Sbjct: 258 LMEGRL 263 Score = 30.8 bits (68), Expect = 3.7 Identities = 18/71 (25%), Positives = 30/71 (42%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + + F SG ++T S+D ++ D+ G+++ L G A T A Sbjct: 228 HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287 Query: 261 SGDDAGCIKVW 293 SG + VW Sbjct: 288 SGGSDEQVMVW 298 Score = 29.6 bits (65), Expect = 8.2 Identities = 28/130 (21%), Positives = 52/130 (40%), Gaps = 4/130 (3%) Frame = +3 Query: 39 ADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGD 218 A+ LER F K H+D+ V F + + +GS D ++ ++ R H D Sbjct: 6 AEDPSLERHF--KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFT-GHKD 62 Query: 219 AINRLVCLTETT----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQIL 386 A+ C+ + +ASG +++W + F H + + + + + Sbjct: 63 AVT---CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFV 119 Query: 387 ATSGDGTLSV 416 S D T+ V Sbjct: 120 TASDDKTVKV 129
>MET30_YEAST (P39014) F-box protein MET30 (Methionine requiring protein 30) (E3| ubiquitin ligase complex SCF(Met30) subunit MET30) Length = 640 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/114 (28%), Positives = 55/114 (48%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H D ++F + ++ TGS D +I D+ TGK+I RL H D + L + Sbjct: 299 KGHMDGVLTLQF--NYRLLFTGSYDSTIGIWDLFTGKLIRRL-SGHSDGVKTLY-FDDRK 354 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + +G I+VW+ C +T+ H D S ++ + I++ S D T+ V Sbjct: 355 LITGSLDKTIRVWNYITGECISTYRGHSD--SVLSVDSYQKVIVSGSADKTVKV 406 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/69 (33%), Positives = 34/69 (49%) Frame = +3 Query: 123 TVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTR 302 T +L+ D +I DV+TGK I R H + + + + SG G IKVWD + Sbjct: 523 THLLSCGLDNTIKLWDVKTGKCI-RTQFGHVEGVWDIAA-DNFRIISGSHDGSIKVWDLQ 580 Query: 303 QRSCCNTFH 329 C +TF+ Sbjct: 581 SGKCMHTFN 589 Score = 32.0 bits (71), Expect = 1.7 Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 6/116 (5%) Frame = +3 Query: 6 LITGEL----HMFRYADGLPLERLFAEKPHKDSCRAVRFVDS-GTVILTGSADMSIVASD 170 LITG L ++ Y G E + + H DS V VDS VI++GSAD ++ Sbjct: 355 LITGSLDKTIRVWNYITG---ECISTYRGHSDS---VLSVDSYQKVIVSGSADKTVKVWH 408 Query: 171 VETGKVIARLDDAHGDAINRLVCLTET-TVASGDDAGCIKVWDTRQRSCCNTFHRH 335 VE+ H + +N + ++ + S D I++WD R SC F H Sbjct: 409 VESRTCYTLR--GHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGH 462 Score = 30.4 bits (67), Expect = 4.8 Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 15/70 (21%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAH-------------GDAINRL--VCLTETTVAS 263 I++GS D SI D+++GK + + GD + + VC+ ++ S Sbjct: 565 IISGSHDGSIKVWDLQSGKCMHTFNGRRLQRETQHTQTQSLGDKVAPIACVCIGDSECFS 624 Query: 264 GDDAGCIKVW 293 GD+ GC+K++ Sbjct: 625 GDEFGCVKMY 634
>TAF5L_HUMAN (O75529) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/134 (20%), Positives = 53/134 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H V+F + + TGS D ++ + G + G ++ +A Sbjct: 425 HLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLA 484 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 S + +K+WD + H D I+ +T+ S I + S D ++ V +R Sbjct: 485 SAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYC 544 Query: 441 KSQSEFSEDELLSL 482 + ++ S EL+ + Sbjct: 545 SAPADGSSSELVGV 558
>PRP4_PONPY (Q5NVD0) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) Length = 521 Score = 41.2 bits (95), Expect = 0.003 Identities = 34/152 (22%), Positives = 59/152 (38%), Gaps = 1/152 (0%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E + ++ H + F G++ TG D D+ TG+ I L+ + Sbjct: 355 EEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINF 414 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG-DGTLS 413 +A+G KVWD RQR C T H++ ++ + + L T D T Sbjct: 415 SPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAK 474 Query: 414 VNSLRGNRVKSQSEFSEDELLSLVIMKNGQKV 509 + + G E +++ L I +GQ + Sbjct: 475 IWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 506
>LIS1_RAT (P63004) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/99 (25%), Positives = 44/99 (44%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 G +L+GS D +I DV TG + L L + S D ++VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + C T + HE +++ + + + ++ S D T+ V Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 405 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/114 (23%), Positives = 49/114 (42%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H DS + + F SG ++ + SADM+I D + + I + + + + Sbjct: 146 KGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 205 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + S IK+W+ + C TF H +++ + I + S D T+ V Sbjct: 206 IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 259 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V++ +DA IKVWD T H D + D+++ + + S D T+ + +G Sbjct: 123 VSASEDA-TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY--SWGHFKDCSDRFLGHAQSVDN 608 + + S+ IM NG +V + + ++ G+ C F GH + V Sbjct: 182 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY---CVKTFTGHREWVRM 238 Query: 609 LLKLDEETLISAAAD 653 + + TLI++ ++ Sbjct: 239 VRPNQDGTLIASCSN 253 Score = 30.0 bits (66), Expect = 6.3 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 10/175 (5%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE--TT 254 H + +V + +G I++ S D +I +V+TG + H + + R+V + T Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT-GHREWV-RMVRPNQDGTL 247 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS---- 422 +AS + ++VW + C HE + +++ S + G+ + S Sbjct: 248 IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPG 307 Query: 423 ---LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF-KDCSD 575 L G+R K+ + + L+ + V G +L +S G F C+D Sbjct: 308 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRG-----VLFHSGGKFILSCAD 357
>LIS1_MOUSE (P63005) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/99 (25%), Positives = 44/99 (44%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 G +L+GS D +I DV TG + L L + S D ++VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + C T + HE +++ + + + ++ S D T+ V Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 405 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/114 (23%), Positives = 49/114 (42%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H DS + + F SG ++ + SADM+I D + + I + + + + Sbjct: 146 KGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 205 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + S IK+W+ + C TF H +++ + I + S D T+ V Sbjct: 206 IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 259 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V++ +DA IKVWD T H D + D+++ + + S D T+ + +G Sbjct: 123 VSASEDA-TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY--SWGHFKDCSDRFLGHAQSVDN 608 + + S+ IM NG +V + + ++ G+ C F GH + V Sbjct: 182 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY---CVKTFTGHREWVRM 238 Query: 609 LLKLDEETLISAAAD 653 + + TLI++ ++ Sbjct: 239 VRPNQDGTLIASCSN 253 Score = 30.0 bits (66), Expect = 6.3 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 10/175 (5%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE--TT 254 H + +V + +G I++ S D +I +V+TG + H + + R+V + T Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT-GHREWV-RMVRPNQDGTL 247 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS---- 422 +AS + ++VW + C HE + +++ S + G+ + S Sbjct: 248 IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPG 307 Query: 423 ---LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF-KDCSD 575 L G+R K+ + + L+ + V G +L +S G F C+D Sbjct: 308 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRG-----VLFHSGGKFILSCAD 357
>LIS1_MACFA (Q8HXX0) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/99 (25%), Positives = 44/99 (44%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 G +L+GS D +I DV TG + L L + S D ++VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + C T + HE +++ + + + ++ S D T+ V Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 405 Score = 39.3 bits (90), Expect = 0.010 Identities = 27/114 (23%), Positives = 49/114 (42%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H DS + + F SG ++ + SADM+I D + + I + + + + Sbjct: 146 KGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 205 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + S IK+W+ + C TF H +++ + I + S D T+ V Sbjct: 206 LVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 259 Score = 39.3 bits (90), Expect = 0.010 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V++ +DA IKVWD T H D + D+++ + + S D T+ + +G Sbjct: 123 VSASEDA-TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGF 181 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY--SWGHFKDCSDRFLGHAQSVDN 608 + + S+ IM NG +V + + ++ G+ C F GH + V Sbjct: 182 ECIRTMHGHDHNVSSVAIMPNGDHLVSASRDKTIKMWEVQTGY---CVKTFTGHREWVRM 238 Query: 609 LLKLDEETLISAAAD 653 + + TLI++ ++ Sbjct: 239 VRPNQDGTLIASCSN 253
>LIS1_HUMAN (P43034) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/99 (25%), Positives = 44/99 (44%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 G +L+GS D +I DV TG + L L + S D ++VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + C T + HE +++ + + + ++ S D T+ V Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 405 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/114 (23%), Positives = 49/114 (42%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H DS + + F SG ++ + SADM+I D + + I + + + + Sbjct: 146 KGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 205 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + S IK+W+ + C TF H +++ + I + S D T+ V Sbjct: 206 IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 259 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V++ +DA IKVWD T H D + D+++ + + S D T+ + +G Sbjct: 123 VSASEDA-TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY--SWGHFKDCSDRFLGHAQSVDN 608 + + S+ IM NG +V + + ++ G+ C F GH + V Sbjct: 182 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY---CVKTFTGHREWVRM 238 Query: 609 LLKLDEETLISAAAD 653 + + TLI++ ++ Sbjct: 239 VRPNQDGTLIASCSN 253 Score = 30.0 bits (66), Expect = 6.3 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 10/175 (5%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE--TT 254 H + +V + +G I++ S D +I +V+TG + H + + R+V + T Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT-GHREWV-RMVRPNQDGTL 247 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS---- 422 +AS + ++VW + C HE + +++ S + G+ + S Sbjct: 248 IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPG 307 Query: 423 ---LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF-KDCSD 575 L G+R K+ + + L+ + V G +L +S G F C+D Sbjct: 308 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRG-----VLFHSGGKFILSCAD 357
>LIS1_BOVIN (P43033) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 41.2 bits (95), Expect = 0.003 Identities = 25/99 (25%), Positives = 44/99 (44%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 G +L+GS D +I DV TG + L L + S D ++VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + C T + HE +++ + + + ++ S D T+ V Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKV 405 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V++ +DA IKVWD T H D + D+++ + + S D T+ + +G Sbjct: 123 VSASEDA-TIKVWDYETGDFERTLKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY--SWGHFKDCSDRFLGHAQSVDN 608 + + S+ IM NG +V + + ++ G+ C F GH + V Sbjct: 182 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY---CVKTFTGHREWVRM 238 Query: 609 LLKLDEETLISAAAD 653 + + TLI++ ++ Sbjct: 239 VRPNQDGTLIASCSN 253 Score = 39.7 bits (91), Expect = 0.008 Identities = 27/114 (23%), Positives = 48/114 (42%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H DS + F SG ++ + SADM+I D + + I + + + + Sbjct: 146 KGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 205 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + S IK+W+ + C TF H +++ + I + S D T+ V Sbjct: 206 IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 259 Score = 30.0 bits (66), Expect = 6.3 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 10/175 (5%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE--TT 254 H + +V + +G I++ S D +I +V+TG + H + + R+V + T Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT-GHREWV-RMVRPNQDGTL 247 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS---- 422 +AS + ++VW + C HE + +++ S + G+ + S Sbjct: 248 IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPG 307 Query: 423 ---LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF-KDCSD 575 L G+R K+ + + L+ + V G +L +S G F C+D Sbjct: 308 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRG-----VLFHSGGKFILSCAD 357
>WD51A_MOUSE (Q8JZX3) WD-repeat protein 51A| Length = 405 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/158 (18%), Positives = 62/158 (39%), Gaps = 4/158 (2%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 + H + R+V F G ++T S D ++ + + L IN + C + Sbjct: 100 RAHTATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQRFLFSLTQH----INWVRCAKFSP 155 Query: 255 ----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + S D +K+WD R C +++ H +++ + + I A D T+ V Sbjct: 156 DGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGAL 536 R +R+ + + +L +G ++ + L Sbjct: 216 ARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTL 253 Score = 38.9 bits (89), Expect = 0.014 Identities = 26/126 (20%), Positives = 52/126 (41%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 LF+ H + R +F G +I++ S D ++ D + + I + G Sbjct: 138 LFSLTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECIHSYCEHGGFVTYVDFHP 197 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 + T +A+ +KVWD R + H ++ +++ + ++ S D TL + Sbjct: 198 SGTCIAAAGMDNTVKVWDARTHRLLQHYQLHSAAVNALSFHPSGNYLITASSDSTLKILD 257 Query: 423 LRGNRV 440 L R+ Sbjct: 258 LMEGRL 263 Score = 32.3 bits (72), Expect = 1.3 Identities = 19/71 (26%), Positives = 31/71 (43%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + A+ F SG ++T S+D ++ D+ G+++ L G A T A Sbjct: 228 HSAAVNALSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287 Query: 261 SGDDAGCIKVW 293 SG + VW Sbjct: 288 SGGSDEQVMVW 298 Score = 30.4 bits (67), Expect = 4.8 Identities = 29/132 (21%), Positives = 54/132 (40%), Gaps = 4/132 (3%) Frame = +3 Query: 54 LERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL 233 LER F K H+D+ V F + + +GS D +++ ++ R H DA+ Sbjct: 11 LERHF--KGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFT-GHKDAVT-- 65 Query: 234 VCLTETT----VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGD 401 C+ + +ASG +++W + F H + + + + ++ S D Sbjct: 66 -CVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSLVTASDD 124 Query: 402 GTLSVNSLRGNR 437 T+ V S R Sbjct: 125 KTVKVWSTHRQR 136
>WDR1_CHICK (O93277) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)| Length = 609 Score = 41.2 bits (95), Expect = 0.003 Identities = 53/221 (23%), Positives = 86/221 (38%), Gaps = 15/221 (6%) Frame = +3 Query: 36 YADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL--DDA 209 + +G P + F H VRF G T SAD I D +TG+ + L A Sbjct: 175 FFEGPPFKFKFTLSDHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGGGKA 234 Query: 210 HGDAINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSD 377 H I + +++ ASGD K+WD S +TF+ + + + + D Sbjct: 235 HDGGIYAISWSPDSSQLLSASGDKTA--KIWDVGANSVVSTFNMGSNVLDQQLGCLWQKD 292 Query: 378 QILATSGDGTLSVNSLRGNR-------VKSQSEFSEDELLSLVIMKNGQKVVCGTPSGAL 536 +L+ S G +N L N +K S+ + L + KNG K + S Sbjct: 293 HLLSLSLSG--YINYLDKNNPDKPLRVIKGHSK----SIQCLTVHKNGGKSYIYSGSNDG 346 Query: 537 LLYSWGHFKDCSDRF--LGHAQSVDNLLKLDEETLISAAAD 653 + W +D F GH V + + + L++ + D Sbjct: 347 HINYWDSDTGENDGFSGKGHTNQVSRMAVDEMDQLVTCSMD 387
>WDR53_MOUSE (Q9DB94) WD-repeat protein 53| Length = 358 Score = 41.2 bits (95), Expect = 0.003 Identities = 59/224 (26%), Positives = 88/224 (39%), Gaps = 25/224 (11%) Frame = +3 Query: 42 DGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDA 221 DG PL + E D +V F S L S +I DV + K LD H + Sbjct: 39 DGTPLGHMQLEGA--DDVTSVLFSASCPTKLYASHGETISVLDVRSLK--GSLDHFHVNE 94 Query: 222 INRLVCL----TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILA 389 + CL TE+ +AS DD+G IK+ D ++ + RH + S + + Q L Sbjct: 95 -EEINCLSLNETESLLASADDSGAIKILDLEKKKVTRSLKRHSNICSSVAFRPQRPQSLV 153 Query: 390 TSG-DGTLSVNSLRGNRVKSQSEFSEDE------------LL------SLVIMKNGQKVV 512 + G D + + SL+ R + EDE LL S+ + G Sbjct: 154 SCGLDMQVMLWSLQKARPVWITNLQEDETEETEGPQTPGRLLNPALAHSVSVASCGNIFS 213 Query: 513 CGTPSGALLLYSWGHFKDCSDR--FLGHAQSVDNLLKLDEETLI 638 CG G + ++ K C F GH V + L E +L+ Sbjct: 214 CGAEDGKVRIFRVMGVK-CERELGFKGHTLGVSQVCFLPESSLL 256
>PRP4_HUMAN (O43172) U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60| kDa protein) (WD splicing factor Prp4) (hPrp4) Length = 522 Score = 41.2 bits (95), Expect = 0.003 Identities = 34/152 (22%), Positives = 59/152 (38%), Gaps = 1/152 (0%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E + ++ H + F G++ TG D D+ TG+ I L+ + Sbjct: 356 EEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINF 415 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG-DGTLS 413 +A+G KVWD RQR C T H++ ++ + + L T D T Sbjct: 416 SPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAK 475 Query: 414 VNSLRGNRVKSQSEFSEDELLSLVIMKNGQKV 509 + + G E +++ L I +GQ + Sbjct: 476 IWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 507
>CSTF1_RAT (Q5BJQ6) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 5/120 (4%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK--VIARLDDAHGDAINR 230 +R F + R++ F SG IL G+ ++ D+ T + V D H DAI Sbjct: 208 KRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICS 267 Query: 231 LVCLTETTV-ASGDDAGCIKVWDTRQRSCCNTFHRHED--YISDMTYVAGSDQILATSGD 401 + + +G GCIK+WD C TF + D + + S IL++ D Sbjct: 268 VNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKD 327 Score = 37.0 bits (84), Expect = 0.051 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 3/164 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK CR + G +I TGSAD SI D E +++A+ A+ V + ET Sbjct: 107 HKGPCRVATYSRDGQLIATGSADASIKILDTE--RMLAK------SAMPIEVMMNETAQQ 158 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNR 437 + ++ I+ T + H D ++ + + ++QILA+ S D TL + Sbjct: 159 NMENHPVIR-----------TLYDHVDEVTCLAF-HPTEQILASGSRDYTLKLFDYSKPS 206 Query: 438 VKSQSEFSEDE--LLSLVIMKNGQKVVCGTPSGALLLYSWGHFK 563 K ++ ++ L S+ +G ++ GT L LY F+ Sbjct: 207 AKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQ 250
>CSTF1_MOUSE (Q99LC2) Cleavage stimulation factor, 50 kDa subunit (CSTF 50 kDa| subunit) (CF-1 50 kDa subunit) (CstF-50) Length = 431 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 5/120 (4%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK--VIARLDDAHGDAINR 230 +R F + R++ F SG IL G+ ++ D+ T + V D H DAI Sbjct: 208 KRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICS 267 Query: 231 LVCLTETTV-ASGDDAGCIKVWDTRQRSCCNTFHRHED--YISDMTYVAGSDQILATSGD 401 + + +G GCIK+WD C TF + D + + S IL++ D Sbjct: 268 VNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKD 327 Score = 37.0 bits (84), Expect = 0.051 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 3/164 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK CR + G +I TGSAD SI D E +++A+ A+ V + ET Sbjct: 107 HKGPCRVATYSRDGQLIATGSADASIKILDTE--RMLAK------SAMPIEVMMNETAQQ 158 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNR 437 + ++ I+ T + H D ++ + + ++QILA+ S D TL + Sbjct: 159 NMENHPVIR-----------TLYDHVDEVTCLAF-HPTEQILASGSRDYTLKLFDYSKPS 206 Query: 438 VKSQSEFSEDE--LLSLVIMKNGQKVVCGTPSGALLLYSWGHFK 563 K ++ ++ L S+ +G ++ GT L LY F+ Sbjct: 207 AKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQ 250
>KMHB_DICDI (P90648) Myosin heavy chain kinase B (EC 2.7.11.7) (MHCK B)| Length = 732 Score = 41.2 bits (95), Expect = 0.003 Identities = 33/146 (22%), Positives = 65/146 (44%), Gaps = 1/146 (0%) Frame = +3 Query: 117 SGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWD 296 SG + +GS D +I D++T + L H + +C+ T + SG I+VW+ Sbjct: 591 SGQYLFSGSNDKTIKVWDLKTFRCNYTLK-GHTKWVTT-ICILGTNLYSGSYDKTIRVWN 648 Query: 297 TRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNRVKSQSEFSEDEL 473 + C T H+ ++ M D++L T S D T+ + L R + E + Sbjct: 649 LKSLECSATLRGHDRWVEHMVI---CDKLLFTASDDNTIKIWDLETLRCNTTLEGHNATV 705 Query: 474 LSLVIMKNGQKVVCGTPSGALLLYSW 551 L + ++ + V+ + ++ ++ W Sbjct: 706 QCLAVWEDKKCVISCSHDQSIRVWGW 731 Score = 38.1 bits (87), Expect = 0.023 Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 2/164 (1%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKV--IARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 ++ TG +D SI D ++ + + L G + +C + + SG IKVWD Sbjct: 472 LLFTGCSDNSIRVYDYKSQNMECVQTLKGHEGPVES--ICYNDQYLFSGSSDHSIKVWDL 529 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLS 479 ++ C T H+ + T + + + S D T+ V L+ K E + + Sbjct: 530 KKLRCIFTLEGHDKPVH--TVLLNDKYLFSGSSDKTIKVWDLKTLECKYTLESHARAVKT 587 Query: 480 LVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL 611 L I +GQ + G+ + ++ F+ C+ GH + V + Sbjct: 588 LCI--SGQYLFSGSNDKTIKVWDLKTFR-CNYTLKGHTKWVTTI 628
>GBB_ORYSA (Q40687) Guanine nucleotide-binding protein beta subunit| Length = 380 Score = 40.8 bits (94), Expect = 0.004 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 8/135 (5%) Frame = +3 Query: 48 LPLERLFA-EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA----RLDDAH 212 +P+ R+ K + SC+ V D T ++T S D + V DV TG+ I+ H Sbjct: 147 IPVSRILTGHKGYVSSCQYVP--DQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGH 204 Query: 213 -GDAINRLVCLTETTV-ASGDDAGCIKVWDTRQRS-CCNTFHRHEDYISDMTYVAGSDQI 383 D ++ + + + + SG +++WD R S T+H HE I+ + + + Sbjct: 205 TADVLSLSINSSNSNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRF 264 Query: 384 LATSGDGTLSVNSLR 428 S DGT + +R Sbjct: 265 GTGSDDGTCRLFDVR 279 Score = 29.6 bits (65), Expect = 8.2 Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 11/130 (8%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETG---KVIARLDDAHGDAINRLV----C 239 H+ +V+F G TGS D + DV TG +V +R D + + + + Sbjct: 248 HEGDINSVKFFPDGQRFGTGSDDGTCRLFDVRTGHQLQVYSREPDRNDNELPTVTSIAFS 307 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCC----NTFHRHEDYISDMTYVAGSDQILATSGDGT 407 ++ + +G G VWDT N + HE IS + + + S D Sbjct: 308 ISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNSHEGRISCLGLSSDGSALCTGSWDKN 367 Query: 408 LSVNSLRGNR 437 L + + G+R Sbjct: 368 LKIWAFSGHR 377
>LIS1_DROME (Q7KNS3) Lissencephaly-1 homolog (Lissencephaly1) (Dlis1) (DLis-1)| Length = 411 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 8/112 (7%) Frame = +3 Query: 126 VILTGSADMSIVASDVE-TGKVIARLDDAHGDAINRLVCLTETT-------VASGDDAGC 281 V LT S D + D E T + IA +A AIN +ASG Sbjct: 261 VWLTNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKT 320 Query: 282 IKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 I++WD C T H++++ + + G +++ S D T+ V LR R Sbjct: 321 IRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKR 372 Score = 36.2 bits (82), Expect = 0.088 Identities = 31/116 (26%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL-TET 251 K H DS + V F G ++ + SAD+SI D + + H ++ + + Sbjct: 147 KGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGD 206 Query: 252 TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSV 416 V S IK+W+ C T+ H +++ M V I AT S D T+ V Sbjct: 207 YVLSASRDRTIKMWEVATGYCVKTYTGHREWVR-MVRVHIEGSIFATCSNDQTIRV 261
>UTP15_BRARE (Q7ZW33) U3 small nucleolar RNA-associated protein 15 homolog| Length = 517 Score = 40.8 bits (94), Expect = 0.004 Identities = 49/190 (25%), Positives = 78/190 (41%), Gaps = 4/190 (2%) Frame = +3 Query: 87 DSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTET-TVAS 263 D+ F G +++ GS + I D+ G+V R H A++ L++ V S Sbjct: 81 DTAYGGSFRGDGKLLVAGSEEGLIRLFDIG-GRVSLRQFKGHSKAVHATSFLSDGFRVLS 139 Query: 264 GDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNRV 440 G D +VWD ++ H DYI + + + T S D T+ + +R Sbjct: 140 GSDDLTCRVWDVASAVELSSITEHTDYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRSGN- 198 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGT--PSGALLLYSWGHFKDCSDRFLGHAQSVDNLL 614 S++ M++GQ V C PS ALL+ + G + D G Q V L Sbjct: 199 ------------SVMTMQHGQPVECVLLYPSEALLVSTGGRYVKVWDLLKGGQQLVS--L 244 Query: 615 KLDEETLISA 644 K +T+ A Sbjct: 245 KNHHKTVTCA 254
>LE14B_PRUAR (O24467) LEC14B homolog| Length = 475 Score = 40.8 bits (94), Expect = 0.004 Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Frame = +3 Query: 99 AVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT---VASGD 269 +VRF G ++ S D SI D++ KV R+ AH +N VC + T + SG Sbjct: 217 SVRFSTDGRELVAASRDASIYVYDLQANKVNLRIP-AHSSDVNT-VCFADETGHLIYSGS 274 Query: 270 DAGCIKVWDTR 302 D KVWD R Sbjct: 275 DDNLCKVWDRR 285
>PWP2_SCHPO (Q9C1X1) Periodic tryptophan protein 2 homolog| Length = 854 Score = 40.8 bits (94), Expect = 0.004 Identities = 26/117 (22%), Positives = 57/117 (48%), Gaps = 2/117 (1%) Frame = +3 Query: 207 AHGDAINRLVCLTE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQI 383 +H DA++ L ++ + +G D G IKVWD C TF +H +S + + + + Sbjct: 337 SHYDALSTLQYSSDGQRIITGADDGKIKVWDMNSGFCIVTFTQHTSAVSGLCFSKRGNVL 396 Query: 384 LATSGDGTLSV-NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSW 551 ++S DG++ + +R ++ + S + + + +G+ +VC + ++ W Sbjct: 397 FSSSLDGSVRAWDLIRYRNFRTFTAPSRVQFSCIAVDPSGE-IVCAGSQDSFEIFMW 452
>TAF5_YEAST (P38129) Transcription initiation factor TFIID subunit 5| (TBP-associated factor 5) (TBP-associated factor 90 kDa) (TAFII-90) Length = 798 Score = 40.8 bits (94), Expect = 0.004 Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 1/136 (0%) Frame = +3 Query: 60 RLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC 239 R+FA H + V F +G + TGS+D + DV TG + I+ VC Sbjct: 603 RIFAG--HLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVC 660 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRH-EDYISDMTYVAGSDQILATSGDGTLSV 416 +++G + G I VWD H ++ I ++Y + +++ D T+ V Sbjct: 661 PDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRV 720 Query: 417 NSLRGNRVKSQSEFSE 464 L+ + +E E Sbjct: 721 WDLKKATTEPSAEPDE 736
>POF1_SCHPO (P87053) F-box/WD-repeat protein pof1 (Skp1-binding protein 1)| Length = 605 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 1/111 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTET-TV 257 H DS + F T++++GSAD ++ GK I H +N + + + V Sbjct: 352 HTDSVLCLTF--DSTLLVSGSADCTVKLWHFSGGKRITLR--GHTGPVNSVRIIRDRGLV 407 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 SG D IK+W +C +TF H + + ++ + S DGT+ Sbjct: 408 LSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSL--ALADSRLFSCSLDGTI 456 Score = 38.5 bits (88), Expect = 0.018 Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 3/194 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H D ++ V + ++ +GS D +I ++ T + +A L+ H + L + + Sbjct: 272 HSDGVMCLQLVRN--ILASGSYDATIRLWNLATFQQVALLE-GHSSGVTCLQ-FDQCKLI 327 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR---G 431 SG I++W+ R C + H H D + +T+ D L SG +V G Sbjct: 328 SGSMDKTIRIWNYRTSECISILHGHTDSVLCLTF----DSTLLVSGSADCTVKLWHFSGG 383 Query: 432 NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL 611 R+ + + S+ I+++ V+ G+ + ++S C F H V + Sbjct: 384 KRITLRGH--TGPVNSVRIIRDRGLVLSGSDDSTIKIWSL-ETNTCLHTFSAHIGPVQS- 439 Query: 612 LKLDEETLISAAAD 653 L L + L S + D Sbjct: 440 LALADSRLFSCSLD 453
>YKY4_CAEEL (Q17963) Hypothetical WD-repeat protein C14B1.4| Length = 376 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/178 (17%), Positives = 71/178 (39%), Gaps = 5/178 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT----E 248 HK + + +++ S D ++ ++ T ++ L + N + C Sbjct: 128 HKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHN----NYVFCCNFNPQS 183 Query: 249 TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV-NSL 425 + V SG +++WD + C T H D +S +++ I + S DG + + ++ Sbjct: 184 SLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTA 243 Query: 426 RGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQS 599 G +K+ + + + NG+ ++ L L+ + K ++ GH S Sbjct: 244 NGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLK-QYTGHENS 300
>UTP15_XENTR (Q5XGE2) U3 small nucleolar RNA-associated protein 15 homolog| Length = 515 Score = 40.4 bits (93), Expect = 0.005 Identities = 49/204 (24%), Positives = 82/204 (40%), Gaps = 14/204 (6%) Frame = +3 Query: 84 KDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTET-TVA 260 KD+ F G ++ G D + D+ +GK R H A++ + + + Sbjct: 80 KDTAYCGTFRGDGKLLAAGCEDSVVQLFDI-SGKAALRQFSGHSKAVHFVDFTADKYRIV 138 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG D ++WD +++ H DYI T +D S D T+ + R ++ Sbjct: 139 SGSDDYTSRLWDIPNGVEITSYNEHTDYIRCGCTSALNNDLFATGSYDHTIKIFDGRTDK 198 Query: 438 VKSQSEFSEDELLSLVIMKNGQKV--VCGTPSGALLLYSWGHFKDCSDRFLG-------- 587 S++ M +GQ V V PSG LL+ + G + D G Sbjct: 199 -------------SVMSMDHGQPVESVLLFPSGGLLVSAGGRYVKVWDILKGGQLLVSLR 245 Query: 588 -HAQSVDNL-LKLDEETLISAAAD 653 H ++V +L L + L+SA+ D Sbjct: 246 NHHKTVTSLCLSSSGQRLLSASLD 269
>PRL1_ARATH (Q42384) PP1/PP2A phosphatases pleiotropic regulator PRL1| Length = 486 Score = 40.4 bits (93), Expect = 0.005 Identities = 46/192 (23%), Positives = 69/192 (35%), Gaps = 1/192 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H R+V F S TGSAD +I DV TG + L V T + Sbjct: 175 HLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIEQVRGLAVSNRHTYMF 234 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 S D +K WD Q ++H H + + D +L D V +R Sbjct: 235 SAGDDKQVKCWDLEQNKVIRSYHGHLSGVYCLALHPTLDVLLTGGRDSVCRVWDIRTKMQ 294 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNL-LK 617 ++ + S+ +VV G+ + + + K S H +SV + L Sbjct: 295 IFALSGHDNTVCSVFTRPTDPQVVTGSHDTTIKFWDLRYGKTMS-TLTHHKKSVRAMTLH 353 Query: 618 LDEETLISAAAD 653 E SA+AD Sbjct: 354 PKENAFASASAD 365
>LIS1_PANTR (Q5IS43) Platelet-activating factor acetylhydrolase IB alpha| subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) Length = 409 Score = 40.0 bits (92), Expect = 0.006 Identities = 27/114 (23%), Positives = 49/114 (42%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT 254 K H DS + + F SG ++ + SADM+I D + + I + + + + Sbjct: 146 KGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDH 205 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + S IK+W+ + C TF H +++ + I + S D T+ V Sbjct: 206 IVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRV 259 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V++ +DA IKVWD T H D + D+++ + + S D T+ + +G Sbjct: 123 VSASEDA-TIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 181 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY--SWGHFKDCSDRFLGHAQSVDN 608 + + S+ IM NG +V + + ++ G+ C F GH + V Sbjct: 182 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGY---CVKTFTGHREWVRM 238 Query: 609 LLKLDEETLISAAAD 653 + + TLI++ ++ Sbjct: 239 VRPNQDGTLIASCSN 253 Score = 38.9 bits (89), Expect = 0.014 Identities = 24/99 (24%), Positives = 43/99 (43%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 G +L+GS D +I DV TG + L L + S D ++VWD Sbjct: 307 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDY 366 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + C T + HE +++ + + + ++ D T+ V Sbjct: 367 KNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGFVDQTVKV 405 Score = 30.0 bits (66), Expect = 6.3 Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 10/175 (5%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE--TT 254 H + +V + +G I++ S D +I +V+TG + H + + R+V + T Sbjct: 190 HDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFT-GHREWV-RMVRPNQDGTL 247 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS---- 422 +AS + ++VW + C HE + +++ S + G+ + S Sbjct: 248 IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPG 307 Query: 423 ---LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF-KDCSD 575 L G+R K+ + + L+ + V G +L +S G F C+D Sbjct: 308 PFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRG-----VLFHSGGKFILSCAD 357
>AAMP_PONPY (Q5RCG7) Angio-associated migratory cell protein| Length = 434 Score = 40.0 bits (92), Expect = 0.006 Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 19/191 (9%) Frame = +3 Query: 15 GELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA 194 G + ++ G P+ L + H+ V G++ILTGS D TGKV+ Sbjct: 237 GTIRIWDLKQGSPIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAKLVSATTGKVVG 296 Query: 195 RL--------------DDAHGDAINRL-VCLTETTVASGDDAGCIKVWD----TRQRSCC 317 +++ +++ L C A G G + ++D T + C Sbjct: 297 VFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQC- 355 Query: 318 NTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKN 497 +H+ I + + AG+ + S DG + + R R+ + E+L + K+ Sbjct: 356 ----QHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKD 411 Query: 498 GQKVVCGTPSG 530 VV T SG Sbjct: 412 ASLVV--TTSG 420
>AAMP_HUMAN (Q13685) Angio-associated migratory cell protein| Length = 434 Score = 40.0 bits (92), Expect = 0.006 Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 19/191 (9%) Frame = +3 Query: 15 GELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA 194 G + ++ G P+ L + H+ V G++ILTGS D TGKV+ Sbjct: 237 GTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVG 296 Query: 195 RL--------------DDAHGDAINRL-VCLTETTVASGDDAGCIKVWD----TRQRSCC 317 +++ +++ L C A G G + ++D T + C Sbjct: 297 VFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQC- 355 Query: 318 NTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKN 497 +H+ I + + AG+ + S DG + + R R+ + E+L + K+ Sbjct: 356 ----QHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKD 411 Query: 498 GQKVVCGTPSG 530 VV T SG Sbjct: 412 ASLVV--TTSG 420
>AAMP_CANFA (Q7YR70) Angio-associated migratory cell protein| Length = 435 Score = 40.0 bits (92), Expect = 0.006 Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 19/191 (9%) Frame = +3 Query: 15 GELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA 194 G + ++ G P+ L + H+ V G++ILTGS D TGKV+ Sbjct: 238 GTIRIWDLKQGSPIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAQLVSATTGKVVG 297 Query: 195 RL--------------DDAHGDAINRL-VCLTETTVASGDDAGCIKVWD----TRQRSCC 317 +++ +++ L C A G G + ++D T + C Sbjct: 298 VFRPETVASQPNVGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLSTQTLRHQC- 356 Query: 318 NTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKN 497 +H+ I + + AG+ + S DG + + R R+ + E+L + K+ Sbjct: 357 ----QHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKD 412 Query: 498 GQKVVCGTPSG 530 VV T SG Sbjct: 413 ASLVV--TTSG 421
>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C| Length = 515 Score = 40.0 bits (92), Expect = 0.006 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 8/122 (6%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL---- 242 K H + V + G VI TGS D +I D ++G+ + H I L Sbjct: 183 KGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHL 242 Query: 243 ----TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 ++ +AS G IK+WDT R C T H + +S + + G + + S D T+ Sbjct: 243 VKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKW-GGQGLLYSGSHDRTV 301 Query: 411 SV 416 V Sbjct: 302 RV 303 Score = 36.6 bits (83), Expect = 0.067 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 10/149 (6%) Frame = +3 Query: 141 SADMSIVASD---------VETGKVIARLDDAHGDAINRLVCLTETT-VASGDDAGCIKV 290 S +M + ASD +++ K IAR+ H +N + + + S IK+ Sbjct: 370 SEEMMVTASDDYTMFLWNPLKSTKPIARMT-GHQKLVNHVAFSPDGRYIVSASFDNSIKL 428 Query: 291 WDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDE 470 WD R +TF H + + + + +++ S D TL V +R ++ +DE Sbjct: 429 WDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDE 488 Query: 471 LLSLVIMKNGQKVVCGTPSGALLLYSWGH 557 + ++ +G++V G + L W H Sbjct: 489 VYTVDWSVDGKRVCSGGKDKMVRL--WTH 515
>GBLP_YEAST (P38011) Guanine nucleotide-binding protein beta subunit-like| protein (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase) Length = 318 Score = 40.0 bits (92), Expect = 0.006 Identities = 40/186 (21%), Positives = 73/186 (39%), Gaps = 6/186 (3%) Frame = +3 Query: 9 ITGELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKV 188 +TG+ F G+P+ K H + G L+ S D ++ DV TG+ Sbjct: 46 LTGDDQKF----GVPVRSF---KGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGET 98 Query: 189 IARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV- 365 R D ++ + + + SG IKVW T + C T H D++S + V Sbjct: 99 YQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVW-TIKGQCLATLLGHNDWVSQVRVVP 157 Query: 366 ---AGSDQILATSGDGTLSVNSLRGNRVKSQSEF--SEDELLSLVIMKNGQKVVCGTPSG 530 A D + S V + N+ + +++F + +L +G + G Sbjct: 158 NEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDG 217 Query: 531 ALLLYS 548 ++L++ Sbjct: 218 EIMLWN 223
>PWP2_HUMAN (Q15269) Periodic tryptophan protein 2 homolog| Length = 919 Score = 39.7 bits (91), Expect = 0.008 Identities = 19/61 (31%), Positives = 31/61 (50%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 + +G D G +KVW+T C TF H ++ +T+ A ++ +S DGT+ L Sbjct: 388 IVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRY 447 Query: 435 R 437 R Sbjct: 448 R 448
>DOA1_YEAST (P36037) Protein DOA1| Length = 715 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/139 (23%), Positives = 57/139 (41%) Frame = +3 Query: 132 LTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRS 311 LT SAD +I + KVI H D + L + + S + G IK+ D Sbjct: 154 LTASADKTIKLW--QNDKVIKTFSGIHNDVVRHLAVVDDGHFISCSNDGLIKLVDMHTGD 211 Query: 312 CCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIM 491 T+ HE ++ + + D I++ D T+ + S +K + S+ M Sbjct: 212 VLRTYEGHESFVYCIKLLPNGD-IVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCM 270 Query: 492 KNGQKVVCGTPSGALLLYS 548 NG ++ G+ + ++S Sbjct: 271 SNGD-IIVGSSDNLVRIFS 288
>WDR1_XENLA (Q9W7F2) WD-repeat protein 1 (Actin-interacting protein 1) (XAIP1)| Length = 608 Score = 39.7 bits (91), Expect = 0.008 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 7/143 (4%) Frame = +3 Query: 6 LITG-ELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETG 182 L+TG + + + +G P + F H VRF G+ + + AD I D +TG Sbjct: 162 LVTGSDDNCCAFLEGPPFKFKFTMSDHSRFVNCVRFSPDGSKLASAGADGQIFLYDGKTG 221 Query: 183 KVIARL--DDAHGDAINRLVCL---TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYI 347 + + L AH I + T+ ASGD K+WD S TF+ D + Sbjct: 222 EKVCSLGGSKAHDGGIYAVSWSPDGTQLLSASGDKT--TKIWDVAANSAVTTFNLGSDVL 279 Query: 348 -SDMTYVAGSDQILATSGDGTLS 413 + + D +L+ S G ++ Sbjct: 280 DQQLGCLWQKDYLLSVSLSGYIN 302
>UTP15_CHICK (Q5F3D7) U3 small nucleolar RNA-associated protein 15 homolog| Length = 520 Score = 39.3 bits (90), Expect = 0.010 Identities = 41/163 (25%), Positives = 71/163 (43%), Gaps = 4/163 (2%) Frame = +3 Query: 84 KDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTET-TVA 260 KD+ + D G +++ GS + SI D+ +G+ R D H A++ + L++ + Sbjct: 80 KDAAYCATYRDDGKLLVAGSEEGSIRLFDI-SGRAPLRQFDGHTKAVHVVGFLSDKYRIF 138 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG D +WD + ++ H DY+ D + S D T+ V R Sbjct: 139 SGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDA---R 195 Query: 438 VKSQSEFSEDELLSLVIMKNGQKV--VCGTPSGALLLYSWGHF 560 KS S++ +++G V V PSG LL+ + G + Sbjct: 196 TKS----------SVMTIEHGHPVESVLLFPSGGLLVSAGGRY 228
>PWP2_NEUCR (Q9C270) Periodic tryptophan protein 2 homolog| Length = 899 Score = 39.3 bits (90), Expect = 0.010 Identities = 37/139 (26%), Positives = 61/139 (43%), Gaps = 5/139 (3%) Frame = +3 Query: 210 HGDAINRLVCLTE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQIL 386 H D++N LV + + + D G IKVWDT C TF H I+ + + + Sbjct: 338 HFDSMNSLVYSPDGQRIVTVADDGKIKVWDTESGFCIVTFTEHTSGITACEFSKKGNVLF 397 Query: 387 ATSGDGTLSVNSLRGNRVKSQSEFSEDELLS---LVIMKNGQKVVCGTPSGALLLYSWG- 554 +S DG++ L R ++ F+ E LS + + +G+ V G+ + ++ W Sbjct: 398 TSSLDGSIRAWDL--IRYRNFRTFTAPERLSFSCMAVDPSGEIVAAGSVD-SFDIHIWSV 454 Query: 555 HFKDCSDRFLGHAQSVDNL 611 DR GH V +L Sbjct: 455 QTGQLLDRLSGHEGPVSSL 473 Score = 32.7 bits (73), Expect = 0.97 Identities = 35/163 (21%), Positives = 59/163 (36%), Gaps = 7/163 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV--CLT--- 245 H A F G V+ T S D SI A D+ I + A RL C+ Sbjct: 380 HTSGITACEFSKKGNVLFTSSLDGSIRAWDL-----IRYRNFRTFTAPERLSFSCMAVDP 434 Query: 246 --ETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVN 419 E A D+ I +W + + HE +S + + +++ S D T + Sbjct: 435 SGEIVAAGSVDSFDIHIWSVQTGQLLDRLSGHEGPVSSLAFAPNGGLLVSGSWDRTARIW 494 Query: 420 SLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 S+ S+ ++L + + ++ T G L +S Sbjct: 495 SIFNRTQTSEPLQLNSDVLDIAFRPDSLQIAISTLDGNLSFWS 537
>KTNB1_MOUSE (Q8BG40) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 658 Score = 39.3 bits (90), Expect = 0.010 Identities = 27/123 (21%), Positives = 50/123 (40%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H +VR +I+ GS SI D+E K++ L + + VA Sbjct: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVA 121 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG IK+WD R++ C + H + + + + + + D T+ + L ++ Sbjct: 122 SGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181 Query: 441 KSQ 449 S+ Sbjct: 182 MSE 184 Score = 37.7 bits (86), Expect = 0.030 Identities = 33/151 (21%), Positives = 64/151 (42%), Gaps = 2/151 (1%) Frame = +3 Query: 207 AHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ 380 AH ++ LV + +A+G D + +W + +C + H + + + Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77 Query: 381 ILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 I+A S G++ V L ++ + + SL G+ V G+ + L+ Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR- 136 Query: 561 KDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 K C R+ GH+Q+V L + +++AAD Sbjct: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAAD 167 Score = 29.6 bits (65), Expect = 8.2 Identities = 18/78 (23%), Positives = 33/78 (42%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 +F + H + R +RF G + + + D ++ D+ GK+++ G Sbjct: 140 VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199 Query: 243 TETTVASGDDAGCIKVWD 296 E +ASG I+ WD Sbjct: 200 NEYLLASGSSDRTIRFWD 217
>APAF_BRARE (Q9I9H8) Apoptotic protease-activating factor 1 (Apaf-1)| Length = 1261 Score = 39.3 bits (90), Expect = 0.010 Identities = 38/181 (20%), Positives = 74/181 (40%), Gaps = 16/181 (8%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 L +F+ G E+L + H++ F I T ++D + +VE G +I Sbjct: 641 LRVFKSTSG---EKLLELQAHEEDVLCCAFSPDDRHIATCASDRKVKLWNVERGVLIREF 697 Query: 201 DDAHGDAINRLVCLTET------TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTY 362 + H + IN T T S D ++W+ +++ NT H + ++ + Sbjct: 698 EVEHEEQINHCQ-FTNTGRRVLLATCSNDKFTNTRLWNPNKKTSQNTMFGHMEPVNHCCF 756 Query: 363 VAGSDQILATSGDGTL------SVNSLRGNRVKSQSEFSEDELLSLVIMK----NGQKVV 512 + +S DG+L S N + V S S++E+ ++V +G +++ Sbjct: 757 SPNDLYLATSSSDGSLKLFEVSSANEWKSIDVDSFFPESDEEIKAMVKCSTWSADGSQII 816 Query: 513 C 515 C Sbjct: 817 C 817 Score = 31.6 bits (70), Expect = 2.2 Identities = 31/159 (19%), Positives = 62/159 (38%), Gaps = 3/159 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-- 254 H + +F D +++T S D +I TG+ + H + + + L+ ++ Sbjct: 1007 HTKTVHHCQFTDDCEILITSSEDSTIRVWKWRTGECMVL--QGHMEPVRKFHLLSSSSSP 1064 Query: 255 -VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRG 431 + S G +KVWD + HE + + TS + T V S Sbjct: 1065 HLFSWSFDGTVKVWDLTRGQMLQDLVCHEGAVLSCDVSSDGRLFATTSANRTAKVWSSAS 1124 Query: 432 NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 ++ E +D + S + +++ G +G + L+S Sbjct: 1125 WKMLFLLEGHKDCVRSCRFSWDNKRLATGDDNGEIRLWS 1163
>NLE1_PONPY (Q5RFF8) Notchless homolog 1| Length = 484 Score = 39.3 bits (90), Expect = 0.010 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = +3 Query: 129 ILTGSADMSIVA-SDVETGKVIARLDDAHGDAINRLVCLTETT-VASGDDAGCIKVWDTR 302 +++GS D ++ S E K + R+ H IN+++ ++ VAS IK+WD R Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMT-GHQALINQVLFSPDSRIVASASFDKSIKLWDGR 401 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSL 482 + H + + + A S +++ S D TL V ++ ++ DE+ ++ Sbjct: 402 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 461 Query: 483 VIMKNGQKVVCGTPSGALLLY 545 +GQ+V G L ++ Sbjct: 462 DWSPDGQRVASGGKDKCLRIW 482 Score = 35.4 bits (80), Expect = 0.15 Identities = 38/180 (21%), Positives = 72/180 (40%), Gaps = 6/180 (3%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 + + S D S+ D G+ R+ H ++ L + + S IKVW Sbjct: 218 VASSSKDGSVRIWDTTAGRC-ERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDG 276 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATS----GDGTLSVNSLRGNRVKSQSEFSEDELL 476 C T H +++ T +D L T + +++ L+G S E E L Sbjct: 277 VLCRTLQGHGHWVN--TMALSTDYALRTGAFEPAEASVNPQDLQG----SLQELKERALS 330 Query: 477 SLVIMK--NGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAA 650 +M+ +++V G+ L L+S K R GH ++ +L + ++++A+ Sbjct: 331 RYNLMRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 390 Score = 33.1 bits (74), Expect = 0.74 Identities = 28/123 (22%), Positives = 47/123 (38%), Gaps = 6/123 (4%) Frame = +3 Query: 66 FAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT 245 F K H+ ++ + G + +G + I+ D TGK + R H I L Sbjct: 149 FTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEP 208 Query: 246 ETT------VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 VAS G +++WDT C H ++ + + G + + S D T Sbjct: 209 LHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRT 267 Query: 408 LSV 416 + V Sbjct: 268 IKV 270
>NLE1_HUMAN (Q9NVX2) Notchless homolog 1| Length = 484 Score = 39.3 bits (90), Expect = 0.010 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = +3 Query: 129 ILTGSADMSIVA-SDVETGKVIARLDDAHGDAINRLVCLTETT-VASGDDAGCIKVWDTR 302 +++GS D ++ S E K + R+ H IN+++ ++ VAS IK+WD R Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMT-GHQALINQVLFSPDSRIVASASFDKSIKLWDGR 401 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSL 482 + H + + + A S +++ S D TL V ++ ++ DE+ ++ Sbjct: 402 TGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAV 461 Query: 483 VIMKNGQKVVCGTPSGALLLY 545 +GQ+V G L ++ Sbjct: 462 DWSPDGQRVASGGKDKCLRIW 482 Score = 35.8 bits (81), Expect = 0.11 Identities = 39/180 (21%), Positives = 73/180 (40%), Gaps = 6/180 (3%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 + + S D S+ D G+ R+ H ++ L + + S IKVW Sbjct: 218 VASSSKDGSVRIWDTTAGRC-ERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDG 276 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATS----GDGTLSVNSLRGNRVKSQSEFSEDEL- 473 C T H +++ T +D L T + +++ L+G S E E L Sbjct: 277 VLCRTLQGHGHWVN--TMALSTDYALRTGAFEPAEASVNPQDLQG----SLQELKERALS 330 Query: 474 -LSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAA 650 +LV + +++V G+ L L+S K R GH ++ +L + ++++A+ Sbjct: 331 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 390 Score = 33.1 bits (74), Expect = 0.74 Identities = 28/123 (22%), Positives = 47/123 (38%), Gaps = 6/123 (4%) Frame = +3 Query: 66 FAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT 245 F K H+ ++ + G + +G + I+ D TGK + R H I L Sbjct: 149 FTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEP 208 Query: 246 ETT------VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 VAS G +++WDT C H ++ + + G + + S D T Sbjct: 209 LHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRW-GGDGLLYSASQDRT 267 Query: 408 LSV 416 + V Sbjct: 268 IKV 270
>KTNB1_HUMAN (Q9BVA0) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 655 Score = 39.3 bits (90), Expect = 0.010 Identities = 27/123 (21%), Positives = 50/123 (40%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H +VR +I+ GS SI D+E K++ L + + VA Sbjct: 62 HTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVA 121 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 SG IK+WD R++ C + H + + + + + + D T+ + L ++ Sbjct: 122 SGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKM 181 Query: 441 KSQ 449 S+ Sbjct: 182 MSE 184 Score = 37.7 bits (86), Expect = 0.030 Identities = 33/151 (21%), Positives = 64/151 (42%), Gaps = 2/151 (1%) Frame = +3 Query: 207 AHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ 380 AH ++ LV + +A+G D + +W + +C + H + + + Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77 Query: 381 ILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 I+A S G++ V L ++ + + SL G+ V G+ + L+ Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR- 136 Query: 561 KDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 K C R+ GH+Q+V L + +++AAD Sbjct: 137 KGCVFRYRGHSQAVRCLRFSPDGKWLASAAD 167 Score = 29.6 bits (65), Expect = 8.2 Identities = 18/78 (23%), Positives = 33/78 (42%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 +F + H + R +RF G + + + D ++ D+ GK+++ G Sbjct: 140 VFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199 Query: 243 TETTVASGDDAGCIKVWD 296 E +ASG I+ WD Sbjct: 200 NEYLLASGSSDRTIRFWD 217
>WDR53_HUMAN (Q7Z5U6) WD-repeat protein 53| Length = 358 Score = 38.9 bits (89), Expect = 0.014 Identities = 52/206 (25%), Positives = 79/206 (38%), Gaps = 31/206 (15%) Frame = +3 Query: 114 DSGTVILTGSADMSIVASDVETGKVIA------RLDDAHGDAINRLVCL----TETTVAS 263 D +V+ + S + AS ET V+ LD H + + CL TE +AS Sbjct: 53 DVTSVLFSPSCPTKLYASHGETISVLDVRSLKDSLDHFHVNE-EEINCLSLNQTENLLAS 111 Query: 264 GDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG-DGTLSVNSLRGNRV 440 DD+G IK+ D + + RH + S + + Q L + G D + + SL+ R Sbjct: 112 ADDSGAIKILDLENKKVIRSLKRHSNICSSVAFRPQRPQSLVSCGLDMQVMLWSLQKARP 171 Query: 441 KSQSEFSEDE------------LL------SLVIMKNGQKVVCGTPSGALLLYSWGHFKD 566 + EDE LL S+ + G CG G + ++ K Sbjct: 172 LWITNLQEDETEEMEGPQSPGQLLNPALAHSISVASCGNIFSCGAEDGKVRIFRVMGVK- 230 Query: 567 CSDR--FLGHAQSVDNLLKLDEETLI 638 C F GH V + L E L+ Sbjct: 231 CEQELGFKGHTSGVSQVCFLPESYLL 256
>MEP50_MOUSE (Q99J09) Methylosome protein 50 (MEP50 protein) (WD-repeat protein| 77) Length = 342 Score = 38.9 bits (89), Expect = 0.014 Identities = 43/196 (21%), Positives = 78/196 (39%), Gaps = 17/196 (8%) Frame = +3 Query: 78 PHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDD------------AHGDA 221 P++ C A ++G LT D I+ + + LD+ H D Sbjct: 68 PNEGFCSAGVQTEAGVADLTWVGDKGILVASDSGAVELWELDENETLIVSKFCKYEHDDI 127 Query: 222 INRLVCLTETTVA-SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQI-LATS 395 ++ + L+ T A SG CIK+WD Q+ N++ H ++ + D + L+ S Sbjct: 128 VSTVTVLSSGTQAVSGSKDCCIKIWDLAQQVSLNSYRAHAGQVTCVAASPHKDSVFLSCS 187 Query: 396 GDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQK---VVCGTPSGALLLYSWGHFKD 566 D + + R + SQ + L + + Q+ V G +G++ L + Sbjct: 188 EDSRILLWDTRCPKPASQMACNASGYLPTALAWHPQQSEVFVFGDENGSVSLVDTKN-AS 246 Query: 567 CSDRFLGHAQSVDNLL 614 C+ H+Q V L+ Sbjct: 247 CTLSSAVHSQGVTRLV 262
>WS17_SCHMA (Q26544) WD-repeat protein SL1-17| Length = 301 Score = 38.9 bits (89), Expect = 0.014 Identities = 25/130 (19%), Positives = 56/130 (43%) Frame = +3 Query: 54 LERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL 233 L+ L+ + H+ +V +GT+ + S D I+ D+ETG++ D D Sbjct: 51 LKCLYQFEGHRLGVISVDINSTGTLAASSSLDSQILLWDLETGRLTKTYDGDPADTWTIA 110 Query: 234 VCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLS 413 +A+G GC+ + + + + ++ + Y++ ++ A + +G +S Sbjct: 111 FSPDSRFLATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXLAYISDGSKLAAGTINGLVS 170 Query: 414 VNSLRGNRVK 443 + L V+ Sbjct: 171 ICDLETGSVQ 180 Score = 37.4 bits (85), Expect = 0.039 Identities = 24/113 (21%), Positives = 47/113 (41%), Gaps = 1/113 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGK-VIARLDDAHGDAINRLVCLTETTV 257 H R+V F G ++ + S D I DV G+ VI L+ G ++ + Sbjct: 185 HATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDNRHL 244 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + +++WD + + F+ HED + Y + I++ D ++ + Sbjct: 245 VTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSPQGNNIISVGDDRSIMI 297
>PWP2_YEAST (P25635) Periodic tryptophan protein 2 (U3 small nucleolar| RNA-associated protein 1) (U3 snoRNA-associated protein 1) Length = 923 Score = 38.9 bits (89), Expect = 0.014 Identities = 33/158 (20%), Positives = 65/158 (41%), Gaps = 2/158 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC--LTETT 254 H S AV+F G V+ + S D ++ A D+ + N L E Sbjct: 386 HTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVV 445 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 A D I VW + + HE +S +++ + + + S D T+ + S+ G Sbjct: 446 CAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGR 505 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 + + ++L+L + +G++V T G + +++ Sbjct: 506 SQQVEPIEVYSDVLALSMRPDGKEVAVSTLKGQISIFN 543 Score = 38.1 bits (87), Expect = 0.023 Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 3/150 (2%) Frame = +3 Query: 210 HGDAINRLVCLTE-TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQIL 386 H D+ N L + + V + + G IKVWD C TF H ++ + + + Sbjct: 344 HFDSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMF 403 Query: 387 ATSGDGTLSV-NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWG-HF 560 ++S DGT+ + +R ++ + + L + +G+ VVC ++ W Sbjct: 404 SSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGE-VVCAGSLDNFDIHVWSVQT 462 Query: 561 KDCSDRFLGHAQSVDNLLKLDEETLISAAA 650 D GH V L E +++++A+ Sbjct: 463 GQLLDALSGHEGPVSCLSFSQENSVLASAS 492
>WDR47_HUMAN (O94967) WD-repeat protein 47| Length = 919 Score = 38.5 bits (88), Expect = 0.018 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 11/140 (7%) Frame = +3 Query: 81 HKDSCRAVRFVD---SGTVIL--TGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT 245 H + R + F++ SG IL G+ D +I +D + G+ + L H I L + Sbjct: 707 HDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALS-GHTGHILALYTWS 765 Query: 246 ETTVASGDDAGCIKVWDTRQRSCC----NTFHRHEDYISDMTYVAGSDQILAT-SGDGTL 410 +ASG ++ WD R SC TFH ++ + V S ++LAT D + Sbjct: 766 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVA-VDPSGRLLATGQEDSSC 824 Query: 411 SVNSLRGNR-VKSQSEFSED 467 + +RG R V+S S D Sbjct: 825 MLYDIRGGRMVQSYHPHSSD 844 Score = 32.0 bits (71), Expect = 1.7 Identities = 14/33 (42%), Positives = 19/33 (57%) Frame = +3 Query: 78 PHKDSCRAVRFVDSGTVILTGSADMSIVASDVE 176 PH R+VRF +LTGS DM I +D++ Sbjct: 840 PHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQ 872
>YIRF_SCHPO (Q9P7I3) Hypothetical WD-repeat protein C664.15 in chromosome I| Length = 651 Score = 38.5 bits (88), Expect = 0.018 Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 19/125 (15%) Frame = +3 Query: 111 VDSGTVILTGSADMSIVASDVETGKVIARLD----DAHGDAINRLV-------------- 236 + S V++TG+ D ++ D+ TG+ I LD + H + ++++ Sbjct: 443 LSSDDVLITGADDKTVRQWDIVTGRCIQTLDFVWAETHDTSTSQILVSDTYKQEPFIRAL 502 Query: 237 -CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLS 413 CL + VASG G I++WD R +F H IS + + S+ + + S D ++ Sbjct: 503 DCL-DAAVASGTVDGLIRIWDLRIGLPVRSFIGHTAPISSLQF--DSNHLYSGSYDNSVR 559 Query: 414 VNSLR 428 + LR Sbjct: 560 IWDLR 564
>TAF5L_MOUSE (Q91WQ5) TAF5-like RNA polymerase II p300/CBP-associated| factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) Length = 589 Score = 38.5 bits (88), Expect = 0.018 Identities = 26/134 (19%), Positives = 52/134 (38%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H V+F + + TGS D ++ + G + G ++ +A Sbjct: 425 HLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLA 484 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 S + +K+WD + H D I+ + + S I + S D ++ V +R Sbjct: 485 SAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVRVWDIRSTCC 544 Query: 441 KSQSEFSEDELLSL 482 + ++ S EL+ + Sbjct: 545 NTPADGSSGELVGV 558
>WDR47_MOUSE (Q8CGF6) WD-repeat protein 47| Length = 920 Score = 38.5 bits (88), Expect = 0.018 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 11/140 (7%) Frame = +3 Query: 81 HKDSCRAVRFVD---SGTVIL--TGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT 245 H + R + F++ SG IL G+ D +I +D + G+ + L H I L + Sbjct: 708 HDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALS-GHTGHILALYTWS 766 Query: 246 ETTVASGDDAGCIKVWDTRQRSCC----NTFHRHEDYISDMTYVAGSDQILAT-SGDGTL 410 +ASG ++ WD R SC TFH ++ + V S ++LAT D + Sbjct: 767 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVA-VDPSGRLLATGQEDSSC 825 Query: 411 SVNSLRGNR-VKSQSEFSED 467 + +RG R V+S S D Sbjct: 826 MLYDIRGGRMVQSYHPHSSD 845 Score = 32.0 bits (71), Expect = 1.7 Identities = 14/33 (42%), Positives = 19/33 (57%) Frame = +3 Query: 78 PHKDSCRAVRFVDSGTVILTGSADMSIVASDVE 176 PH R+VRF +LTGS DM I +D++ Sbjct: 841 PHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQ 873
>POF11_SCHPO (Q09855) F-box/WD-repeat protein pof11| Length = 506 Score = 38.5 bits (88), Expect = 0.018 Identities = 26/110 (23%), Positives = 49/110 (44%) Frame = +3 Query: 87 DSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASG 266 DS V++ D ++++GS D ++ DV + ++ +L G + C + SG Sbjct: 222 DSVYCVQYDDE--IMVSGSKDRTVSVWDVNSRFILYKLYGHSGSVLCLDFCRRRNLLVSG 279 Query: 267 DDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 I +WD + R + H D + + V + I+++S D T V Sbjct: 280 SSDSTIIIWDWQNRRPLKVYFGHTDNV--LGVVVSENYIISSSRDHTARV 327
>LE14B_LITER (Q40153) LEC14B protein| Length = 473 Score = 38.5 bits (88), Expect = 0.018 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Frame = +3 Query: 99 AVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT---VASGD 269 +++F G I+ G++D SI D+E ++ R+ AH +N VC + + + SG Sbjct: 219 SIKFSTDGREIVAGTSDESICVYDLEADRLSLRIS-AHESDVNS-VCFADESGHLIYSGS 276 Query: 270 DAGCIKVWDTR 302 D KVWD R Sbjct: 277 DDNLCKVWDRR 287
>COPB2_SCHPO (O42937) Probable coatomer subunit beta' (Beta'-coat protein)| (Beta'-COP) Length = 796 Score = 38.1 bits (87), Expect = 0.023 Identities = 29/101 (28%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV-NSLRG 431 + +GDD IKVWD + ++C H + +S + + I++ S DGT+ + ++L Sbjct: 202 ITAGDD-NLIKVWDYQTKACVRILEGHTNNVSFAFFHSKFPIIISGSEDGTVKIWHTLSY 260 Query: 432 NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWG 554 + +KS + FS D + K+ V G +G L+ +S G Sbjct: 261 SLIKSYN-FSLDRAWCIAQNKDNGLVTVGFDNG-LITFSLG 299 Score = 33.1 bits (74), Expect = 0.74 Identities = 27/139 (19%), Positives = 56/139 (40%), Gaps = 2/139 (1%) Frame = +3 Query: 243 TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNS 422 TE V + G + +W+ ++ +F ++ I ++A + + S D + V + Sbjct: 25 TEPWVIASHYNGQVGIWNYNTQTLVRSFDINDVPIRACAFIARKNWFVCGSDDFQVRVYN 84 Query: 423 LRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSV 602 +Q E D + +LV+ ++ + + ++W C F GH++ V Sbjct: 85 YNTGEKVTQFEAHPDYIRALVVHPTQPFLLTSSDDMTIKCFNWDMSWKCVQTFEGHSRYV 144 Query: 603 DNLL--KLDEETLISAAAD 653 +L D T S+ D Sbjct: 145 MSLAINPKDTNTFASSCLD 163
>WDR41_MOUSE (Q3UDP0) WD-repeat protein 41| Length = 460 Score = 38.1 bits (87), Expect = 0.023 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 5/104 (4%) Frame = +3 Query: 78 PHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT---- 245 P DSC A S ++LT SAD ++ D +TG+ I R+ + + CLT Sbjct: 94 PPLDSCEA-----SSQLLLTASADRTVGVWDCDTGRQIQRVTCFQ----STVKCLTVLQR 144 Query: 246 -ETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGS 374 + ++ G D G VW+ + C T H + IS + + G+ Sbjct: 145 LDIWLSGGSDLG---VWNRKLDLLCKTSHLSDTGISALVEIPGN 185
>YNA6_YEAST (P41318) Hypothetical 34.0 kDa Trp-Asp repeats-containing protein| in SIS1-MRPL2 intergenic region Length = 303 Score = 38.1 bits (87), Expect = 0.023 Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 7/140 (5%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 V S +D G IKVWD R S + +H ++++ ++++ DG + + L N Sbjct: 91 VTSSED-GTIKVWDVRSPSIPRNY-KHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGEN 148 Query: 435 RVKSQSEFSED-ELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCS-----DRFLGHAQ 596 + Q +D L SL + +G + G ++ + D S +F H+ Sbjct: 149 QCTHQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLKPVTKFRAHST 208 Query: 597 SVDN-LLKLDEETLISAAAD 653 + LL D + L + +AD Sbjct: 209 YITRILLSSDVKHLATCSAD 228
>PWP2_MOUSE (Q8BU03) Periodic tryptophan protein 2 homolog| Length = 919 Score = 37.7 bits (86), Expect = 0.030 Identities = 28/133 (21%), Positives = 53/133 (39%), Gaps = 1/133 (0%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 + +G D G +KVW+T C T H ++ +T+ I+ +S DGT+ L Sbjct: 388 IVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRY 447 Query: 435 RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWG-HFKDCSDRFLGHAQSVDNL 611 R S V + + ++V + ++ W D GH V L Sbjct: 448 RNFRTFTSPRPTQFSCVAVDSSGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGL 507 Query: 612 LKLDEETLISAAA 650 ++++++A+ Sbjct: 508 CFNPMKSILASAS 520
>YAGE_SCHPO (Q9UTN4) Hypothetical WD-repeat protein C12G12.14c in chromosome I| Length = 509 Score = 37.4 bits (85), Expect = 0.039 Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 2/118 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H+ R V F + + +T S D S+ + +L D ++ +A Sbjct: 163 HEMEVRDVAFSPNDSKFVTASDDGSLKVWNFHMSTEELKLTGHGWDVKTVDWHPSKGLLA 222 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVA--GSDQILATSGDGTLSVNSLR 428 SG +K WD R +C T H H++ I ++ GS+ + S D T V LR Sbjct: 223 SGSKDNLVKFWDPRTGTCIATLHGHKNTIMQASFQKNFGSNYLATVSRDSTCRVFDLR 280
>AIP1_YEAST (P46680) Actin-interacting protein 1| Length = 615 Score = 37.4 bits (85), Expect = 0.039 Identities = 19/57 (33%), Positives = 30/57 (52%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWD 296 ++ TGS D +I V+ I + +AH D +N L+ T +T+ S CIK W+ Sbjct: 555 LVATGSLDTNIFIYSVKRPMKIIKALNAHKDGVNNLLWETPSTLVSSGADACIKRWN 611
>GBB_SOLTU (P93563) Guanine nucleotide-binding protein beta subunit| Length = 377 Score = 37.4 bits (85), Expect = 0.039 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 9/138 (6%) Frame = +3 Query: 42 DGL-PLERLFA-EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA----RLD 203 DG+ P+ R+ + K + SC+ V D T ++T S D + V D+ TG + Sbjct: 143 DGIHPVSRMLSGHKGYVSSCQYVP--DEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQ 200 Query: 204 DAH-GDAINRLVCLTETTV-ASGDDAGCIKVWDTRQRSCCN-TFHRHEDYISDMTYVAGS 374 H D ++ + + + SG ++WDTR S TFH HE ++ + + Sbjct: 201 SGHTADVLSVSISSSNPKLFVSGSCDTTARLWDTRVASRAQRTFHGHESDVNTVKFFPDG 260 Query: 375 DQILATSGDGTLSVNSLR 428 ++ S DG+ + +R Sbjct: 261 NRFGTGSDDGSCRLFDIR 278 Score = 33.9 bits (76), Expect = 0.43 Identities = 31/128 (24%), Positives = 47/128 (36%), Gaps = 9/128 (7%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGD-----AINRLVCLT 245 H+ V+F G TGS D S D+ TG + + HGD + ++ Sbjct: 247 HESDVNTVKFFPDGNRFGTGSDDGSCRLFDIRTGHQLQVYNQPHGDGDIPHVTSMAFSIS 306 Query: 246 ETTVASGDDAGCIKVWDTRQRSCC----NTFHRHEDYISDMTYVAGSDQILATSGDGTLS 413 + G G VWDT + + HE IS + A + S D L Sbjct: 307 GRLLFVGYSNGDCYVWDTLLAKVVLNLGSVQNSHEGRISCLGLSADGSALCTGSWDTNLK 366 Query: 414 VNSLRGNR 437 + + G+R Sbjct: 367 IWAFGGHR 374
>TAF5_DROME (P49846) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 85 kDa subunit) (p85) (TAFII-80) Length = 704 Score = 37.4 bits (85), Expect = 0.039 Identities = 25/112 (22%), Positives = 44/112 (39%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H V+F + + TGS+D ++ D TG+ + + G + +A Sbjct: 533 HLSDVDCVQFHPNSNYVATGSSDRTVRLWDNMTGQSVRLMTGHKGSVSSLAFSACGRYLA 592 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 SG I +WD S T RH ++ +T+ + A D L++ Sbjct: 593 SGSVDHNIIIWDLSNGSLVTTLLRHTSTVTTITFSRDGTVLAAAGLDNNLTL 644
>UTP15_XENLA (Q7ZXZ2) U3 small nucleolar RNA-associated protein 15 homolog| Length = 515 Score = 37.0 bits (84), Expect = 0.051 Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 4/163 (2%) Frame = +3 Query: 84 KDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTET-TVA 260 KD+ + G ++ G D + D+ +GK R H A++ + ++ + Sbjct: 80 KDTAYCGTYRGDGKLLAAGCEDSVVQLFDI-SGKAALRQFSGHSKAVHFVDFTSDKYRIV 138 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYI-SDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 SG D K+WD ++ H DYI T +D S D T+ V R ++ Sbjct: 139 SGSDDYTSKLWDIPNGIEIASYKEHTDYIRCGCTSSLNNDLFATGSYDHTIKVFDGRTDK 198 Query: 438 VKSQSEFSEDELLSLVIMKNGQKV--VCGTPSGALLLYSWGHF 560 S++ M +GQ V V PSG LL+ + G + Sbjct: 199 -------------SVMSMDHGQPVESVLLFPSGGLLVSAGGRY 228
>LIN23_CAEEL (Q09990) F-box/WD-repeat protein lin-23 (Abnormal cell lineage| protein 23) Length = 665 Score = 37.0 bits (84), Expect = 0.051 Identities = 45/179 (25%), Positives = 77/179 (43%), Gaps = 3/179 (1%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWD--- 296 VI++GS+D ++ DVETG+ I L H +A+ L V D I VWD Sbjct: 274 VIISGSSDATVRVWDVETGECIKTLIH-HCEAVLHLRFANGIMVTCSKDRS-IAVWDMVS 331 Query: 297 TRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELL 476 R + H ++ + + I++ SGD T+ V S+ + ++ + Sbjct: 332 PRDITIRRVLVGHRAAVNVVDF--DDRYIVSASGDRTIKVWSM--DTLEFVRTLAGHRRG 387 Query: 477 SLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 + G+ VV G+ + L+ H C GH + V ++ DE+ ++S A D Sbjct: 388 IACLQYRGRLVVSGSSDNTIRLWDI-HSGVCLRVLEGHEELV-RCIRFDEKRIVSGAYD 444 Score = 34.3 bits (77), Expect = 0.33 Identities = 20/59 (33%), Positives = 34/59 (57%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWD 296 G ++++GS+D +I D+ +G V R+ + H + + R + E + SG G IKVWD Sbjct: 395 GRLVVSGSSDNTIRLWDIHSG-VCLRVLEGHEELV-RCIRFDEKRIVSGAYDGKIKVWD 451 Score = 32.7 bits (73), Expect = 0.97 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 3/136 (2%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR-G 431 + SG IK+WD + SC H + + Y + I++ S D T+ V + G Sbjct: 235 IVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQY--DNRVIISGSSDATVRVWDVETG 292 Query: 432 NRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDR--FLGHAQSVD 605 +K+ E L + NG V C + ++ ++ +D + R +GH +V Sbjct: 293 ECIKTLIHHCEAVL--HLRFANGIMVTC-SKDRSIAVWDMVSPRDITIRRVLVGHRAAV- 348 Query: 606 NLLKLDEETLISAAAD 653 N++ D+ ++SA+ D Sbjct: 349 NVVDFDDRYIVSASGD 364
>YJL2_YEAST (P47025) Hypothetical 80.0 kDa Trp-Asp repeats-containing protein in| ASF1-CCT7 intergenic region Length = 714 Score = 37.0 bits (84), Expect = 0.051 Identities = 37/171 (21%), Positives = 68/171 (39%), Gaps = 22/171 (12%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAI--------NRLV 236 H D A+ S +++GS D +I D+ +GK + +D + + + ++ Sbjct: 501 HTDEVTALSLDPS--FLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKST 558 Query: 237 CLTE--------------TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGS 374 LT+ +A+G G +++WD R T H D I+ + + S Sbjct: 559 LLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKF--DS 616 Query: 375 DQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPS 527 ++ S D T+ + LR + +S L + +N VV PS Sbjct: 617 ACLVTGSYDRTVRIWDLRTGLLNKFHAYSAPVLSLDLFQENAAVVVADEPS 667
>WDR16_HUMAN (Q8N1V2) WD-repeat protein 16 (WD40-repeat protein up-regulated in| HCC) Length = 620 Score = 37.0 bits (84), Expect = 0.051 Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 3/109 (2%) Frame = +3 Query: 90 SCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTVASG 266 +C + F+ G I++ D I A ETG+++ +++AH + + ++ V SG Sbjct: 376 TCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISG 435 Query: 267 DDAGCIKVWD--TRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 G ++VW + + H+ +S + +++ + S DGT Sbjct: 436 GGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGT 484 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 2/96 (2%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTR 302 I+T D I +V G VI L+ + +IN + E V G+D +KVWD Sbjct: 517 IITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDH-LVKVWDYN 575 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 + + H I+ + G+ I++ S DG + Sbjct: 576 EGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAI 611
>PLAP_MOUSE (P27612) Phospholipase A-2-activating protein (PLAP)| Length = 646 Score = 37.0 bits (84), Expect = 0.051 Identities = 34/156 (21%), Positives = 64/156 (41%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + AV+ + ++LTGSAD +I + G+ R H D + L L+ET Sbjct: 93 HTAAVWAVKILPEQGLMLTGSADKTIKL--WKAGR-CERTFLGHEDCVRGLAILSETEFL 149 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 S + I+ W C + H +YI ++ S + T+ D +L + + Sbjct: 150 SCANDASIRRWQI-TGECLEVYFGHTNYIYSISVFPNSKDFVTTAEDRSLRI--WKHGEC 206 Query: 441 KSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 + +++NG +V G G + +++ Sbjct: 207 AQTIRLPAQSIWCCCVLENGD-IVVGASDGIIRVFT 241
>LIN53_CAEEL (P90916) Probable histone-binding protein lin-53 (Abnormal cell| lineage protein 53) Length = 417 Score = 36.6 bits (83), Expect = 0.067 Identities = 43/154 (27%), Positives = 67/154 (43%), Gaps = 11/154 (7%) Frame = +3 Query: 204 DAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQ-RSCCNTFHRHEDYISDMTYVAGS 374 DAH +N L +E +A+G + +WD R R ++F H D I + + + Sbjct: 262 DAHSAEVNCLAFNPYSEFILATGSADKTVALWDLRNLRMKLHSFESHRDEIFQVQWSPHN 321 Query: 375 DQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSW 551 + ILA+SG D L V L +E +ED L+ + G + + +SW Sbjct: 322 ETILASSGTDKRLHVWDLSKIGEDQSAEDAEDGPPELLFIHGGH-------TAKISDFSW 374 Query: 552 GHFKD---CS---DRFLGHAQSVDNLL-KLDEET 632 + CS D L Q DN+ ++DEET Sbjct: 375 NPNEPWVVCSVSEDNILQVWQMADNIYNEVDEET 408
>YK02_SCHPO (Q9HDY9) Hypothetical serine/threonine-rich protein P11E10.02c| precursor Length = 1082 Score = 36.6 bits (83), Expect = 0.067 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 8/71 (11%) Frame = -2 Query: 274 ASSPEATVVSVRHTRRFMASP----CASSKRAMTLPVSTSEATI----DISADPVRITVP 119 +SS T VS+ T S AS+ + TLPVSTSEAT+ DI A P ++ P Sbjct: 212 SSSETLTSVSITSTESAYTSSSVDIAASTTASSTLPVSTSEATVSFSTDIPATPSTLSSP 271 Query: 118 ESTNRTALHES 86 S++ + L E+ Sbjct: 272 ASSSSSYLVET 282
>WD42_DICDI (P54686) WD-repeat protein 2| Length = 597 Score = 36.6 bits (83), Expect = 0.067 Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 8/192 (4%) Frame = +3 Query: 102 VRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL----TETTVASGD 269 VRF G ++T AD D +TG+ + L+ A C + + Sbjct: 197 VRFSPDGNKLVTVGADKKAFVYDGKTGEKLIELNPAQQHTGGIYGCSWSADNNRVLTASA 256 Query: 270 DAGCIKVWDTRQRSCCNTFHRHEDYISD--MTYVAGSDQILATSGDGTLSVNSLRGNRVK 443 D C K+WDT C N+F D ++D + + D +L+ + G +S +L Sbjct: 257 DKSC-KIWDTTTGQCINSFTFGSD-VNDQQLGCLWFGDSLLSVNLAGEISTLNLDDVAKP 314 Query: 444 SQSEFSEDELLSLVIM-KNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHA-QSVDNLLK 617 S+ ++L+ + KN + + +LL W + F G A ++ +K Sbjct: 315 SRVIKGHNKLVGTIAFDKNAGSLYSASYDASLL--QWDLSTGLATNFTGPAHKNQITSIK 372 Query: 618 LDEETLISAAAD 653 ++ + LI+ A D Sbjct: 373 INGDQLITCAMD 384
>PLAP_RAT (P54319) Phospholipase A-2-activating protein (PLAP)| Length = 647 Score = 36.6 bits (83), Expect = 0.067 Identities = 28/112 (25%), Positives = 49/112 (43%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + AV+ + ++LTGSAD +I + G+ R H D + L L+ET Sbjct: 93 HTAAVWAVKILPEQGLMLTGSADKTIKL--WKAGR-CERTFSGHEDCVRGLAILSETEFL 149 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 S + I+ W C ++ H +YI ++ + T+ D +L + Sbjct: 150 SCANDASIRRWQI-TGECLGVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRI 200
>SRW1_SCHPO (O13286) WD-repeat-containing protein srw1 (Suppressor of rad/wee1)| Length = 556 Score = 36.6 bits (83), Expect = 0.067 Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 13/189 (6%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT-ETTVASGDDAGCIKVWDTR 302 V+ +G D I+ DV + R+ AH + L + E +ASG + + VWD Sbjct: 345 VLSSGGRDNHILHRDVRAPEHYFRVLTAHRQEVCGLEWNSNENLLASGGNDNALMVWDKF 404 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSG---DGTLSV-NSLRGNRVKSQSEFSEDE 470 + +FH H + +T+ ILA+ G D T+ + N+ RG+ + + S + Sbjct: 405 EEKPLYSFHNHIAAVKAITWSPHQRGILASGGGTADRTIKLWNTQRGSMLHNIDTGS--Q 462 Query: 471 LLSLVIMKNGQKVVC--GTPSGALLLYSW------GHFKDCSDRFLGHAQSVDNLLKLDE 626 + +L+ K + + G + L+++ G K +DR L A S + Sbjct: 463 VCNLLWSKQTNEFISTHGFMENEVALWNYPSVSRVGTLKGHTDRVLYLAMSPNG------ 516 Query: 627 ETLISAAAD 653 E +++ AAD Sbjct: 517 ENIVTGAAD 525
>PRP17_MOUSE (Q9DC48) Pre-mRNA-splicing factor PRP17 (Cell division cycle 40| homolog) Length = 579 Score = 36.6 bits (83), Expect = 0.067 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 10/165 (6%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV--CL---- 242 H + R + F +GT L+ + D + D ETG+ I+R NR V C+ Sbjct: 331 HSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRF-------TNRKVPYCVKFNP 383 Query: 243 ---TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLS 413 + +G I WD R + RH ++ + +V + + ++TS D +L Sbjct: 384 DEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLR 443 Query: 414 VNSLR-GNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 V K +E S + ++ + NG+ + C + +L++ Sbjct: 444 VWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIF 488
>PRP17_HUMAN (O60508) Pre-mRNA-splicing factor PRP17 (hPRP17) (Cell division| cycle 40 homolog) (EH-binding protein 3) (Ehb3) Length = 579 Score = 36.6 bits (83), Expect = 0.067 Identities = 37/165 (22%), Positives = 69/165 (41%), Gaps = 10/165 (6%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV--CL---- 242 H + R + F +GT L+ + D + D ETG+ I+R NR V C+ Sbjct: 331 HSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRF-------TNRKVPYCVKFNP 383 Query: 243 ---TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLS 413 + +G I WD R + RH ++ + +V + + ++TS D +L Sbjct: 384 DEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLR 443 Query: 414 VNSLR-GNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 V K +E S + ++ + NG+ + C + +L++ Sbjct: 444 VWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIF 488
>KTNB1_BRARE (Q7ZUV2) Katanin p80 WD40-containing subunit B1 homolog| Length = 694 Score = 36.2 bits (82), Expect = 0.088 Identities = 26/113 (23%), Positives = 49/113 (43%), Gaps = 1/113 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRL-VCLTETTV 257 H + ++F S ++ GS S+ D+E K++ L H +I+ L + Sbjct: 62 HTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTLM-GHKASISSLDFHPMGEYL 120 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 ASG IK+WD R++ C + H + + + + + S D T+ + Sbjct: 121 ASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKL 173 Score = 35.4 bits (80), Expect = 0.15 Identities = 29/151 (19%), Positives = 66/151 (43%), Gaps = 2/151 (1%) Frame = +3 Query: 207 AHGDAINRLVCLTET--TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ 380 AH ++ LV + +A+G + + +W + +C + H + + + + ++ Sbjct: 18 AHSSNVSSLVLGKSSGRLLATGGEDCRVNIWAVSKPNCIMSLTGHTSAVGCIQFNSSEER 77 Query: 381 ILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 ++A S G+L + L ++ + + SL G+ + G+ + L+ Sbjct: 78 VVAGSLSGSLRLWDLEAAKILRTLMGHKASISSLDFHPMGEYLASGSVDSNIKLWDVRR- 136 Query: 561 KDCSDRFLGHAQSVDNLLKLDEETLISAAAD 653 K C R+ GH Q+V L + +++A+D Sbjct: 137 KGCVFRYKGHTQAVRCLAFSPDGKWLASASD 167
>COPA_YEAST (P53622) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| Length = 1201 Score = 36.2 bits (82), Expect = 0.088 Identities = 25/107 (23%), Positives = 40/107 (37%) Frame = +3 Query: 96 RAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDA 275 + + F S +L +I D G ++ R +D G T+ S D Sbjct: 15 KGIAFHPSRPWVLVALFSSTIQLWDYRMGTLLHRFEDHEGPVRGLDFHPTQPIFVSAGDD 74 Query: 276 GCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 IKVW C T H DY+ + + I++ S D T+ + Sbjct: 75 YTIKVWSLDTNKCLYTLTGHLDYVRTVFFHRELPWIISASDDQTIRI 121
>PLAP_HUMAN (Q9Y263) Phospholipase A-2-activating protein (PLAP) (PLA2P)| Length = 738 Score = 36.2 bits (82), Expect = 0.088 Identities = 27/112 (24%), Positives = 49/112 (43%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 H + AV+ + ++LTGSAD ++ + G+ R H D + L L+ET Sbjct: 93 HTAAVWAVKILPEQGLMLTGSADKTVKL--WKAGR-CERTFSGHEDCVRGLAILSETEFL 149 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 S + I+ W C ++ H +YI ++ + T+ D +L + Sbjct: 150 SCANDASIRRWQI-TGECLEVYYGHTNYIYSISVFPNCRDFVTTAEDRSLRI 200
>Y163_SYNY3 (Q55563) Hypothetical WD-repeat protein sll0163| Length = 1693 Score = 36.2 bits (82), Expect = 0.088 Identities = 41/182 (22%), Positives = 68/182 (37%), Gaps = 9/182 (4%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E+L + H D R F G ++LT S D + D+E G+ I N Sbjct: 1128 EQLTLCQGHADWVRNAEFNCHGQILLTASRDGTARLWDLE-GREIGLCQGHTSWVRNAQF 1186 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + G ++WD + C H++++++ + I+ +S DGT V Sbjct: 1187 SPDGQWIVTCSADGTARLWDLSSQ-CFAVLKGHQNWVNNALWSPDGQHIITSSSDGTARV 1245 Query: 417 NSLRGNRVKSQSEFSEDELLSLVIMKNGQKVV---------CGTPSGALLLYSWGHFKDC 569 S G + + + +GQK+V T G LL GH K+ Sbjct: 1246 WSRHG-KCLGTLRGHDHNIHGARFSLDGQKIVTYSTDNTARLWTKEGTLLTILRGHQKEV 1304 Query: 570 SD 575 D Sbjct: 1305 YD 1306 Score = 30.4 bits (67), Expect = 4.8 Identities = 43/196 (21%), Positives = 79/196 (40%), Gaps = 5/196 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT--ETT 254 H+++ A+ + G T SAD ++ G+ +A L H D + + + Sbjct: 1054 HQEAITALDWSADGQYFATASADHTVKLWQ-RHGEEVATLR-GHEDWVRSVHFSPHHQFL 1111 Query: 255 VASGDDAGCIKVWDT--RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 V SG D ++W+ Q + C H D++ + + +L S DGT + L Sbjct: 1112 VTSGQD-NTARIWNFAGEQLTLCQG---HADWVRNAEFNCHGQILLTASRDGTARLWDLE 1167 Query: 429 GNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHFKDCSDRFLGHAQSVDN 608 G + + + + +GQ +V + G L W C GH V+N Sbjct: 1168 GREI-GLCQGHTSWVRNAQFSPDGQWIVTCSADGTARL--WDLSSQCFAVLKGHQNWVNN 1224 Query: 609 LL-KLDEETLISAAAD 653 L D + +I++++D Sbjct: 1225 ALWSPDGQHIITSSSD 1240
>PRP46_ASPFU (Q4WT34) Pre-mRNA-splicing factor prp46 (Pre-mRNA-processing| protein 46) Length = 453 Score = 36.2 bits (82), Expect = 0.088 Identities = 27/107 (25%), Positives = 43/107 (40%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK + ++ ++ I+TGS D ++ D+ GK + L N + E T A Sbjct: 269 HKGTVADLKCQEADPQIITGSLDATVRLWDLAAGKTMGVLTHHKKGVRNLAIHPREFTFA 328 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGD 401 S G IK W + F H I+ + D +L + GD Sbjct: 329 SA-STGSIKQWKCPEGDFMQNFEGHNAVINSL--AVNEDNVLFSGGD 372
>TBLX_MOUSE (Q9QXE7) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) Length = 527 Score = 36.2 bits (82), Expect = 0.088 Identities = 26/105 (24%), Positives = 50/105 (47%) Frame = +3 Query: 114 DSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVW 293 +S ++ + S D ++ DVE G I L + +ASG C+ +W Sbjct: 423 NSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW 482 Query: 294 DTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 +T+ S +++ R I ++ + A D++ A++ DG++ V LR Sbjct: 483 NTQSGSLVHSY-RGTGGIFEVCWNARGDKVGASASDGSVCVLDLR 526 Score = 29.6 bits (65), Expect = 8.2 Identities = 26/116 (22%), Positives = 47/116 (40%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK A+++ G IL+ D + + D TG+ + A++ + TT A Sbjct: 278 HKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD-VDWQNNTTFA 336 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 S CI V TF H + ++ + + + + S D TL + S++ Sbjct: 337 SCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMK 392
>GBB2_TOBAC (P93398) Guanine nucleotide-binding protein beta subunit 2| Length = 377 Score = 36.2 bits (82), Expect = 0.088 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 8/134 (5%) Frame = +3 Query: 51 PLERLFA-EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETG---KVIARLDDAHGD 218 P+ R+ + K + SC+ V D T ++T S D + V D+ TG V + Sbjct: 147 PVSRMLSGHKGYVSSCQYVP--DEDTHVITSSGDQTCVLWDITTGLRTSVFGGEFQSGHT 204 Query: 219 AINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCN-TFHRHEDYISDMTYVAGSDQIL 386 A + V ++ + SG ++WDTR S TF+ HE ++ + + ++ Sbjct: 205 ADVQSVSISSSNPRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFG 264 Query: 387 ATSGDGTLSVNSLR 428 S DGT + +R Sbjct: 265 TGSDDGTCRLFDIR 278 Score = 30.4 bits (67), Expect = 4.8 Identities = 30/128 (23%), Positives = 45/128 (35%), Gaps = 9/128 (7%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGD-----AINRLVCLT 245 H+ V+F G TGS D + D+ TG + HGD + ++ Sbjct: 247 HEGDVNTVKFFPDGNRFGTGSDDGTCRLFDIRTGHQLQVYYQPHGDGDIPHVTSMAFSIS 306 Query: 246 ETTVASGDDAGCIKVWDTRQRSCCNTF----HRHEDYISDMTYVAGSDQILATSGDGTLS 413 + G G VWDT + HE IS + A + S D L Sbjct: 307 GRLLFVGYSNGDCYVWDTLLAKVVLNLGAVQNSHEGRISCLGLSADGSALCTGSWDTNLK 366 Query: 414 VNSLRGNR 437 + + G+R Sbjct: 367 IWAFGGHR 374
>LIS1_CAEEL (Q9NDC9) Lissencephaly-1 homolog (Pronuclear migration abnormal| protein 1) Length = 404 Score = 35.8 bits (81), Expect = 0.11 Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 1/102 (0%) Frame = +3 Query: 114 DSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-VASGDDAGCIKV 290 +S ++ +GS D SI A ++ TG V+ L AH + + L + + S D ++V Sbjct: 300 NSTHILFSGSRDRSIKAWNINTGDVLFTLL-AHENWVRGLAFHPKGKYLISVADDKTLRV 358 Query: 291 WDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 W+ + C HE ++S + + S ++ S D + V Sbjct: 359 WELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKV 400 Score = 35.0 bits (79), Expect = 0.20 Identities = 32/169 (18%), Positives = 60/169 (35%), Gaps = 16/169 (9%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 ++ + H D R +R + GT+ + S D ++ T L D H A+ + Sbjct: 226 VYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRD-HEHAVECVEWA 284 Query: 243 TETTVA----------------SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGS 374 +T SG IK W+ T HE+++ + + Sbjct: 285 PDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKG 344 Query: 375 DQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGT 521 +++ + D TL V L R E E + ++ + V+ G+ Sbjct: 345 KYLISVADDKTLRVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGS 393 Score = 33.5 bits (75), Expect = 0.57 Identities = 28/113 (24%), Positives = 45/113 (39%), Gaps = 1/113 (0%) Frame = +3 Query: 75 KPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL-TET 251 K H D+ + +G +++ S+D+SI D + H ++ + L T Sbjct: 145 KGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGD 204 Query: 252 TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 V S IK WD C TF H D++ +++ S DGTL Sbjct: 205 FVLSASRDHTIKQWDISTGYCVYTFRGHNDWV----------RMIRISNDGTL 247 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/51 (31%), Positives = 24/51 (47%) Frame = +3 Query: 249 TTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGD 401 T +AS + IKVWD T H D ++D+ A Q+++ S D Sbjct: 119 TIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSD 169
>TAF5_HUMAN (Q15542) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 800 Score = 35.8 bits (81), Expect = 0.11 Identities = 34/159 (21%), Positives = 66/159 (41%), Gaps = 5/159 (3%) Frame = +3 Query: 60 RLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC 239 R+FA H RF + + TGSAD ++ DV G + R+ H I+ L Sbjct: 621 RIFAG--HLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCV-RIFTGHKGPIHSLTF 677 Query: 240 LTETT-VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 +A+G G + +WD H D + + + + + + S D T+ + Sbjct: 678 SPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 737 Query: 417 NSLRGNRVKSQSEFSEDELLS----LVIMKNGQKVVCGT 521 + +K+ + D+ + + + +N Q+++ GT Sbjct: 738 ----WDAIKAFEDLETDDFTTATGHINLPENSQELLLGT 772
>SCON2_NEUCR (Q01277) Sulfur controller 2 (SCON2)| Length = 650 Score = 35.8 bits (81), Expect = 0.11 Identities = 32/119 (26%), Positives = 54/119 (45%) Frame = +3 Query: 60 RLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC 239 +L K H++ ++ D+ ++ TGS D +I ++ET + I L H I R + Sbjct: 286 KLSVLKGHENGVTCLQLDDN--ILATGSYDTTIKIWNIETEECIRTLV-GHTAGI-RALQ 341 Query: 240 LTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 ++ + SG IKVW+ C +TF H D + + + D L SG +V Sbjct: 342 FDDSKLISGSLDHTIKVWNWHTGECLSTFAAHTDSVISVHF----DGHLLASGSSDKTV 396
>PRP19_CAEEL (Q10051) PRP19/PSO4 homolog| Length = 492 Score = 35.8 bits (81), Expect = 0.11 Identities = 26/121 (21%), Positives = 54/121 (44%), Gaps = 3/121 (2%) Frame = +3 Query: 117 SGTVILTGSADMSIVASDVETGKVIARLDDAHGD--AINRLVCLTETTV-ASGDDAGCIK 287 SG IL+ S D SD+ +GK + ++ G A++ + + + +G +K Sbjct: 304 SGDYILSASDDSYWAFSDIRSGKSLCKVSVEPGSQIAVHSIEFHPDGLIFGTGAADAVVK 363 Query: 288 VWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSED 467 +WD + ++ F H + + + + S DG + + LR ++K+ F+ + Sbjct: 364 IWDLKNQTVAAAFPGHTAAVRSIAFSENGYYLATGSEDGEVKLWDLR--KLKNLKTFANE 421 Query: 468 E 470 E Sbjct: 422 E 422
>YPR4_CAEEL (Q20059) Hypothetical WD-repeat protein F35G12.4| Length = 683 Score = 35.8 bits (81), Expect = 0.11 Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Frame = +3 Query: 84 KDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT--V 257 KDS ++ + +++L + I D T + I +L H D + LV + T + Sbjct: 178 KDSIYSLATTPNLSLVLGAGTEKCIRLFDPRTNEKIMKLR-GHTDNVRALVVNDDGTRAL 236 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 ++G DA I++WD Q+ C T HE+ + + V S + ++G + V + + Sbjct: 237 SAGSDA-TIRLWDIGQQRCIATCIAHEEGVWTL-QVDSSFTTVYSAGKDKMVVKTPLYDF 294 Query: 438 VKSQSEFSED 467 KSQ F E+ Sbjct: 295 TKSQLLFKEE 304 Score = 30.4 bits (67), Expect = 4.8 Identities = 32/156 (20%), Positives = 65/156 (41%), Gaps = 6/156 (3%) Frame = +3 Query: 204 DAHGDAINRLV-CLTETTVASGDDAGCIKVWDTRQ---RSCCNTFHRHEDYISDMTYVAG 371 + H D +N ++ C + S + +KVW+ + + H+DY+S + Y Sbjct: 87 EQHTDWVNDMILCGHGKILISASNDTTVKVWNIERDNKHGFIDCIRTHKDYVSCLAYAPI 146 Query: 372 SDQILATSGDGTLSVNSLRGN-RVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYS 548 ++ ++ S D + V + N + + +D + SL N V+ + L+ Sbjct: 147 VEKAVSASFDHNIFVYDINANFKTVNNLIGCKDSIYSLATTPNLSLVLGAGTEKCIRLFD 206 Query: 549 WGHFKDCSDRFLGHAQSVDNLLKLDEET-LISAAAD 653 + + GH +V L+ D+ T +SA +D Sbjct: 207 -PRTNEKIMKLRGHTDNVRALVVNDDGTRALSAGSD 241
>WDR16_MOUSE (Q5F201) WD-repeat protein 16| Length = 620 Score = 35.8 bits (81), Expect = 0.11 Identities = 22/109 (20%), Positives = 49/109 (44%), Gaps = 3/109 (2%) Frame = +3 Query: 90 SCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE-TTVASG 266 +C + F+ G I++ D I A E+G+++ ++ AH + + ++ + SG Sbjct: 376 TCHGIDFMRDGKSIISAWDDGKIRAFAPESGRLMYTINSAHRIGVTAIATTSDCKRIISG 435 Query: 267 DDAGCIKVWDT--RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 G ++VW + + H+ +S + +++ + S DGT Sbjct: 436 GGEGEVRVWQVGCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGT 484 Score = 35.0 bits (79), Expect = 0.20 Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 2/96 (2%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTR 302 I+T D I +V G VI L+ + +IN + E V G D +KVWD Sbjct: 517 IITSGTDRKIAYWEVFDGSVIRELEGSLSGSINGMDITQEGGHFVTGGHDH-LVKVWDYN 575 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 + + H I M G+ I++ S DG + Sbjct: 576 EGEVTHVGVGHSGNIMAMRISPGNQYIVSVSADGAI 611
>MORG1_BRARE (Q6DH44) Mitogen-activated protein kinase organizer 1 (MAPK| organizer 1) Length = 315 Score = 35.8 bits (81), Expect = 0.11 Identities = 32/124 (25%), Positives = 56/124 (45%), Gaps = 3/124 (2%) Frame = +3 Query: 141 SADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA-SGDDAGCIKVWDTRQRSC- 314 S+D +++ DV +G+V +L H +N + E TV SG G ++ WDTR R Sbjct: 86 SSDKTVILWDVASGQVTRKLR-GHAGKVNCVQFNEEATVMLSGSIDGTVRCWDTRSRRME 144 Query: 315 -CNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIM 491 +D IS + ++L S DG + LR ++ Q ++ + + Sbjct: 145 PIQILDESQDGISSLK--VSEHELLTGSVDGRVRRYDLRMGQL--QVDYIGSPITCVCFS 200 Query: 492 KNGQ 503 ++GQ Sbjct: 201 RDGQ 204
>HAT2_ASPOR (Q2UA71) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)| Length = 436 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 3/79 (3%) Frame = +3 Query: 69 AEKPHKDSCRAVRFVDSG-TVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC-- 239 AE H+D+ A+ F + TV+ TGSAD SI D+ K + H D++ L Sbjct: 281 AEGQHRDAINAIAFNPAAETVLATGSADKSIGLWDLRNLKTKLHTLECHTDSVTSLSWHP 340 Query: 240 LTETTVASGDDAGCIKVWD 296 E+ +AS I WD Sbjct: 341 FEESVLASASYDRKIMFWD 359
>WDR16_MACFA (Q95JL5) WD-repeat protein 16| Length = 571 Score = 35.4 bits (80), Expect = 0.15 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 2/96 (2%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTR 302 I+T D I +V G VI L+ + +IN + E V G+D +KVWD Sbjct: 468 IITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEGVHFVTGGNDH-LVKVWDYN 526 Query: 303 QRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 + + H I+ + G+ I++ S DG + Sbjct: 527 EGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAI 562
>POP3_SCHPO (O74184) WD-repeat protein pop3 (WD-repeat protein wat1)| Length = 314 Score = 35.4 bits (80), Expect = 0.15 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 2/114 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL-TETTV 257 H ++ A+ F G + T S D ++ D+ V D H +N L+ + + Sbjct: 82 HTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQRNYD--HKSPVNDLLIHPNQGEL 139 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDY-ISDMTYVAGSDQILATSGDGTLSV 416 S D +G ++ WD + SC + ED +S +T + ++A + G V Sbjct: 140 LSCDQSGRVRAWDLGENSCTHELIPEEDVPMSSITVGSDGSMLIAGNNKGNCYV 193
>GBLP_LEIMA (Q25306) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 35.4 bits (80), Expect = 0.15 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 3/109 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV---CLTET 251 H AV F +I++ D I +V + L D H D ++ + L Sbjct: 106 HTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHP 165 Query: 252 TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 V SG IKVW+ C T H +Y+S +T D L SG Sbjct: 166 IVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVT--VSPDGSLCASG 212
>GBLP_LEIIN (P62884) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) (LiP36) (p36Li) Length = 312 Score = 35.4 bits (80), Expect = 0.15 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 3/109 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV---CLTET 251 H AV F +I++ D I +V + L D H D ++ + L Sbjct: 106 HTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHP 165 Query: 252 TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 V SG IKVW+ C T H +Y+S +T D L SG Sbjct: 166 IVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVT--VSPDGSLCASG 212
>GBLP_LEICH (P62883) Guanine nucleotide-binding protein beta subunit-like| protein (Antigen LACK) Length = 312 Score = 35.4 bits (80), Expect = 0.15 Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 3/109 (2%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV---CLTET 251 H AV F +I++ D I +V + L D H D ++ + L Sbjct: 106 HTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHP 165 Query: 252 TVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 V SG IKVW+ C T H +Y+S +T D L SG Sbjct: 166 IVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVT--VSPDGSLCASG 212
>RBBP7_RAT (Q71UF4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +3 Query: 192 ARLDDAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTY 362 + L DAH +N L +E +A+G + +WD R +TF H+D I + + Sbjct: 265 SHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW 324 Query: 363 VAGSDQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 ++ ILA+SG D L+V L + +E +ED L+ + G Sbjct: 325 SPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 371
>RBBP7_MOUSE (Q60973) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +3 Query: 192 ARLDDAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTY 362 + L DAH +N L +E +A+G + +WD R +TF H+D I + + Sbjct: 265 SHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW 324 Query: 363 VAGSDQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 ++ ILA+SG D L+V L + +E +ED L+ + G Sbjct: 325 SPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 371
>RBBP7_MACFA (Q4R304) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +3 Query: 192 ARLDDAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTY 362 + L DAH +N L +E +A+G + +WD R +TF H+D I + + Sbjct: 265 SHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW 324 Query: 363 VAGSDQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 ++ ILA+SG D L+V L + +E +ED L+ + G Sbjct: 325 SPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 371
>RBBP7_HUMAN (Q16576) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) Length = 425 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +3 Query: 192 ARLDDAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTY 362 + L DAH +N L +E +A+G + +WD R +TF H+D I + + Sbjct: 265 SHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW 324 Query: 363 VAGSDQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 ++ ILA+SG D L+V L + +E +ED L+ + G Sbjct: 325 SPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 371
>RBBP7_BOVIN (Q3SWX8) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 35.0 bits (79), Expect = 0.20 Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 4/107 (3%) Frame = +3 Query: 192 ARLDDAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTY 362 + L DAH +N L +E +A+G + +WD R +TF H+D I + + Sbjct: 265 SHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHW 324 Query: 363 VAGSDQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 ++ ILA+SG D L+V L + +E +ED L+ + G Sbjct: 325 SPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 371
>IF122_HUMAN (Q9HBG6) Intraflagellar transport 122 homolog (WD-repeat protein| 10) Length = 1242 Score = 35.0 bits (79), Expect = 0.20 Identities = 32/137 (23%), Positives = 56/137 (40%) Frame = +3 Query: 21 LHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARL 200 L ++ +DG L+ L K HKD+ V + G +GSAD S++ + T K+ L Sbjct: 35 LLVYDTSDGTLLQPL---KGHKDTVYCVAYAKDGKRFASGSADKSVI---IWTSKLEGIL 88 Query: 201 DDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQ 380 H DAI + T + + +W Q+S H+ I ++ Sbjct: 89 KYTHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSK--HKSSSKIICCSWTNDGQY 146 Query: 381 ILATSGDGTLSVNSLRG 431 + +G +S+ + G Sbjct: 147 LALGMFNGIISIRNKNG 163
>KMHA_DICDI (P42527) Myosin heavy chain kinase A (EC 2.7.11.7) (MHCK A)| Length = 1146 Score = 35.0 bits (79), Expect = 0.20 Identities = 22/78 (28%), Positives = 34/78 (43%) Frame = +3 Query: 117 SGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWD 296 SG + +G D I D ET ++ + H D + L C ++ D IK+WD Sbjct: 1004 SGRYLFSGGNDQIIYVWDTETLSMLFNMQ-GHEDWVLSLHCTASYLFSTSKD-NVIKIWD 1061 Query: 297 TRQRSCCNTFHRHEDYIS 350 SC +T H + +S Sbjct: 1062 LSNFSCIDTLKGHWNSVS 1079 Score = 34.3 bits (77), Expect = 0.33 Identities = 26/92 (28%), Positives = 39/92 (42%) Frame = +3 Query: 141 SADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCN 320 S D +I D+ T K I + H I L L+ + SG + I VWDT S Sbjct: 971 SYDKTIKVWDLSTFKEIKSFEGVHTKYIKTLA-LSGRYLFSGGNDQIIYVWDTETLSMLF 1029 Query: 321 TFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 HED++ + A + +TS D + + Sbjct: 1030 NMQGHEDWVLSLHCTA--SYLFSTSKDNVIKI 1059
>FBXW7_HUMAN (Q969H0) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBX30) (hCdc4) (Archipelago homolog) (hAgo) (SEL-10) Length = 707 Score = 35.0 bits (79), Expect = 0.20 Identities = 27/96 (28%), Positives = 44/96 (45%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 +++GS D ++ D+ETG+ + L H A+ R V V SG +KVWD Sbjct: 474 VVSGSRDATLRVWDIETGQCLHVLM-GHVAAV-RCVQYDGRRVVSGAYDFMVKVWDPETE 531 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 +C +T H + + + + D I SG S+ Sbjct: 532 TCLHTLQGHTNRVYSLQF----DGIHVVSGSLDTSI 563
>Y143_SYNY3 (P74442) Hypothetical WD-repeat protein slr0143| Length = 1191 Score = 35.0 bits (79), Expect = 0.20 Identities = 43/210 (20%), Positives = 80/210 (38%), Gaps = 42/210 (20%) Frame = +3 Query: 42 DGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA--------- 194 DG L+ L K H+DS +V F G ++ + S D ++ +GK +A Sbjct: 631 DGNLLQTL---KGHQDSVYSVSFSPDGEILASTSRDRTVRLWHWRSGKTLAVLGGHTKSV 687 Query: 195 ---------------------RLDDAHGDAINRLVCLTETT------------VASGDDA 275 RL D G+ I R L E +A D Sbjct: 688 DDAQFSPDGQTLVSVCRDGQIRLWDLDGNLI-RQFGLPEVAFFGVNWHPNGNLLAVAADD 746 Query: 276 GCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSE 455 G +++W T Q T H+++++ + + Q+ ++S +G++ S G +K Sbjct: 747 GTVRLW-TPQGEIKATLSGHDEFVTRVVFTPDGKQLFSSSSNGSVIHWSTSGKMLKKYQG 805 Query: 456 FSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 + E + L + NG + G + + ++ Sbjct: 806 YPE-AIFGLALASNGALLAIGAENNLVKVW 834
>TAF5_MOUSE (Q8C092) Transcription initiation factor TFIID subunit 5| (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100) Length = 801 Score = 35.0 bits (79), Expect = 0.20 Identities = 34/159 (21%), Positives = 66/159 (41%), Gaps = 5/159 (3%) Frame = +3 Query: 60 RLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVC 239 R+FA H R+ + + TGSAD ++ DV G + R+ H I+ L Sbjct: 622 RIFAG--HLADVNCTRYHPNSNYVATGSADRTVRLWDVLNGNCV-RIFTGHKGPIHSLTF 678 Query: 240 LTETT-VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 +A+G G + +WD H D + + + + + + S D T+ + Sbjct: 679 SPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRL 738 Query: 417 NSLRGNRVKSQSEFSEDELLS----LVIMKNGQKVVCGT 521 + VK+ + D+ + + + +N Q+++ GT Sbjct: 739 ----WDAVKAFEDLETDDFTTATGHINLPENSQELLLGT 773
>FBXW7_MOUSE (Q8VBV4) F-box/WD-repeat protein 7 (F-box and WD-40 domain protein| 7) (F-box protein FBW7) (F-box protein Fbxw6) (F-box-WD40 repeat protein 6) (SEL-10) Length = 629 Score = 35.0 bits (79), Expect = 0.20 Identities = 27/96 (28%), Positives = 44/96 (45%) Frame = +3 Query: 129 ILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQR 308 +++GS D ++ D+ETG+ + L H A+ R V V SG +KVWD Sbjct: 396 VVSGSRDATLRVWDIETGQCLHVLM-GHVAAV-RCVQYDGRRVVSGAYDFMVKVWDPETE 453 Query: 309 SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 +C +T H + + + + D I SG S+ Sbjct: 454 TCLHTLQGHTNRVYSLQF----DGIHVVSGSLDTSI 485
>WDR41_HUMAN (Q9HAD4) WD-repeat protein 41| Length = 459 Score = 34.7 bits (78), Expect = 0.25 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 16/172 (9%) Frame = +3 Query: 78 PHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT---- 245 P +SC + +ILT SAD +++ D +T + + R+ + + CLT Sbjct: 94 PSLESCE-----EKNQLILTASADRTVIVWDGDTTRQVQRISCFQ----STVKCLTVLQR 144 Query: 246 -ETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYV--------AGSDQI---LA 389 + ++ G+D + VW+ + C T H + IS + + G + I L Sbjct: 145 LDVWLSGGND---LCVWNRKLDLLCKTSHLSDTGISALVEIPKNCVVAAVGKELIIFRLV 201 Query: 390 TSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLY 545 +G+L + L R+ +D +LSL+ + N V G+ G L+++ Sbjct: 202 APTEGSLEWDILEVKRLLDH----QDNILSLINV-NDLSFVTGSHVGELIIW 248
>COPA_BOVIN (Q27954) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 34.7 bits (78), Expect = 0.25 Identities = 18/66 (27%), Positives = 31/66 (46%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 + S D I+VW+ + R+C H Y+ + D +++ S D T+ V + G Sbjct: 108 ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGL 167 Query: 435 RVKSQS 452 R K+ S Sbjct: 168 RKKNLS 173 Score = 32.7 bits (73), Expect = 0.97 Identities = 20/52 (38%), Positives = 25/52 (48%) Frame = +3 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 SG D IKVW+ + R C T H DYI + IL+ S D T+ V Sbjct: 68 SGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRV 119
>KTNB1_CHICK (Q5ZIU8) Katanin p80 WD40-containing subunit B1 (Katanin p80| subunit B1) (p80 katanin) Length = 657 Score = 34.7 bits (78), Expect = 0.25 Identities = 24/105 (22%), Positives = 45/105 (42%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQ 305 +I+ GS SI D+E K++ L + + + VASG IK+WD R+ Sbjct: 76 LIVAGSQSGSIRVWDLEAAKILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRR 135 Query: 306 RSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRV 440 + C + H + + + + + + D T+ + L +V Sbjct: 136 KGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKV 180 Score = 32.0 bits (71), Expect = 1.7 Identities = 20/78 (25%), Positives = 33/78 (42%) Frame = +3 Query: 63 LFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL 242 +F K H + R +RF G + + + D ++ D+ GKV+ G Sbjct: 139 IFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKVMFEFTGHSGPVNVVEFHP 198 Query: 243 TETTVASGDDAGCIKVWD 296 +E +ASG I+ WD Sbjct: 199 SEYLLASGSSDRTIRFWD 216
>GBB1_TOBAC (P93397) Guanine nucleotide-binding protein beta subunit 1| Length = 377 Score = 34.7 bits (78), Expect = 0.25 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 8/134 (5%) Frame = +3 Query: 51 PLERLFA-EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETG---KVIARLDDAHGD 218 P+ R+ + K + SC+ V D T ++T S D + V D+ TG V + Sbjct: 147 PVSRMLSGHKGYVSSCQYVP--DEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQSGHT 204 Query: 219 AINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCN-TFHRHEDYISDMTYVAGSDQIL 386 A + V ++ + SG ++WDTR S TF+ HE ++ + + ++ Sbjct: 205 ADVQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFG 264 Query: 387 ATSGDGTLSVNSLR 428 S DGT + +R Sbjct: 265 TGSEDGTCRLFDIR 278
>WDR71_CHICK (Q5ZK69) WD-repeat protein 71| Length = 392 Score = 34.7 bits (78), Expect = 0.25 Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAIN--RLVCLTETT 254 H+ S + G + ++ S D ++ G+ I RL + H +N R Sbjct: 91 HQKSITCLDISSGGGLGVSTSTDGTMKIWQAANGE-IRRLLEGHVYDVNCCRFFPSGLVV 149 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 ++ G DA +K+W SC TF H+ I D V +L+ S DGT Sbjct: 150 LSGGMDAQ-LKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVLSCSRDGT 199 Score = 32.7 bits (73), Expect = 0.97 Identities = 23/100 (23%), Positives = 41/100 (41%) Frame = +3 Query: 15 GELHMFRYADGLPLERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIA 194 G + +++ A+G + RL + +C RF SG V+L+G D + E + Sbjct: 114 GTMKIWQAANG-EIRRLLEGHVYDVNC--CRFFPSGLVVLSGGMDAQLKIWSAEDASCVV 170 Query: 195 RLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSC 314 G ++ + V S G ++WD + SC Sbjct: 171 TFKGHKGGILDTAIVDRGRNVLSCSRDGTARLWDCGKSSC 210
>SWD3_SCHPO (O43017) Set1 complex component swd3 (Set1C component swd3)| (COMPASS component swd3) (Complex proteins associated with set1 protein swd3) Length = 380 Score = 34.3 bits (77), Expect = 0.33 Identities = 33/150 (22%), Positives = 64/150 (42%), Gaps = 1/150 (0%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETT-V 257 H+ S V + I T S+D +I T ++ L H I+++ T + + Sbjct: 53 HEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLF-GHYRGISQVKWATGSKYL 111 Query: 258 ASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 AS D I++WD +R H +Y+S + + +++ S D T+ + +L+ Sbjct: 112 ASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGT 171 Query: 438 VKSQSEFSEDELLSLVIMKNGQKVVCGTPS 527 + ++S+ I +G +C T S Sbjct: 172 CLRMLPAHSEPIISVSISADG--TLCATAS 199
>WDR50_HUMAN (Q9Y5J1) WD-repeat protein 50| Length = 556 Score = 34.3 bits (77), Expect = 0.33 Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Frame = +3 Query: 345 ISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELL---SLVIMKNGQKVVC 515 ++ T+ + S ++ A+SGDG + V + N K + F ++ L S+ +NGQ V C Sbjct: 385 VAASTFSSDSKKVYASSGDGEVYVWDV--NSRKCLNRFVDEGSLYGLSIATSRNGQYVAC 442 Query: 516 GTPSGALLLYS 548 G+ G + +Y+ Sbjct: 443 GSNCGVVNIYN 453
>PRP17_YEAST (P40968) Pre-mRNA-splicing factor PRP17 (Cell division control| protein 40) Length = 455 Score = 34.3 bits (77), Expect = 0.33 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 9/121 (7%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIAR--LDDAHGDAINR-------L 233 H +A+RF + L+ S D S+ D ETGKV R L+ D +R + Sbjct: 205 HNKPIKALRFTEDCQSFLSSSFDRSVKIWDTETGKVKTRLHLNSTPADVESRPTNPHEFI 264 Query: 234 VCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLS 413 V L+ + + DD + + T+ H I + Y + +++S D T+ Sbjct: 265 VGLSNSKILHYDDR------VSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVR 318 Query: 414 V 416 + Sbjct: 319 I 319
>YA4E_SCHPO (Q09731) Hypothetical WD-repeat protein C31A2.14 in chromosome I| Length = 962 Score = 33.9 bits (76), Expect = 0.43 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 5/115 (4%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTE--TT 254 H D+ R + D G ILT S+D +I + K + AH D++ L Sbjct: 215 HTDNVRDILISDDGRTILTASSDATIKLWSLRAQKCLFSF-IAHSDSVWALYSEHPDLKV 273 Query: 255 VASGDDAGCIKVWDTRQR---SCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 +GD +G I D R + C + + +SD+ VA I +TS DG++ Sbjct: 274 FYAGDRSGLITRTDIRNQPNNQSCTAICKQDAPVSDI--VARQSFIWSTSRDGSI 326 Score = 30.4 bits (67), Expect = 4.8 Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 7/111 (6%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAIN-------RLVCLTETTVASGDDAGCI 284 ++ +G D I+ D G+ + R + ++ + +A+G I Sbjct: 139 LVASGGLDKRIIVWDYNVGQEVMRFEQLPDCSLVVGPRSGVYSLAANNNIIANGGLQKDI 198 Query: 285 KVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNR 437 ++WD + H D + D+ IL S D T+ + SLR + Sbjct: 199 QLWDCVSKKRITDLVGHTDNVRDILISDDGRTILTASSDATIKLWSLRAQK 249
>PRP46_ASHGO (Q75BY3) Pre-mRNA-splicing factor PRP46 (Pre-mRNA-processing| protein 46) Length = 425 Score = 33.9 bits (76), Expect = 0.43 Identities = 18/54 (33%), Positives = 30/54 (55%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 V++G D+ ++VWD R RSC T H I+ + + QI++ S D T+ + Sbjct: 214 VSAGRDS-VVRVWDIRSRSCVLTLAGHRGPINKVRCLPVDPQIVSCSTDATVKL 266
>PK1IP_XENLA (Q68FJ6) p21-activated protein kinase-interacting protein 1-like| (PAK1-interacting protein 1-like) Length = 363 Score = 33.9 bits (76), Expect = 0.43 Identities = 18/84 (21%), Positives = 43/84 (51%), Gaps = 2/84 (2%) Frame = +3 Query: 171 VETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYIS 350 +ET V+ +++ I+ +T+ +A D I+++DT + C F HE+ + Sbjct: 190 LETAAVVGTINNPK--RISSAQFITDALIAVAGDEEVIRLYDTASQKCVCEFKAHENRVK 247 Query: 351 DMTYV--AGSDQILATSGDGTLSV 416 ++ + G+ ++++S DG + + Sbjct: 248 NLHVIELQGTHVVVSSSSDGYIKM 271
>COPA_HUMAN (P53621) Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP)| (HEPCOP) (HEP-COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin] Length = 1224 Score = 33.9 bits (76), Expect = 0.43 Identities = 18/66 (27%), Positives = 31/66 (46%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGN 434 + S D I+VW+ + R+C H Y+ + D +++ S D T+ V + G Sbjct: 108 ILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGL 167 Query: 435 RVKSQS 452 R K+ S Sbjct: 168 RKKNLS 173 Score = 32.7 bits (73), Expect = 0.97 Identities = 20/52 (38%), Positives = 25/52 (48%) Frame = +3 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 SG D IKVW+ + R C T H DYI + IL+ S D T+ V Sbjct: 68 SGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRV 119
>FBW1B_HUMAN (Q9UKB1) F-box/WD-repeat protein 11 (F-box/WD-repeat protein 1B)| (F-box and WD-repeats protein beta-TrCP2) Length = 542 Score = 33.5 bits (75), Expect = 0.57 Identities = 36/174 (20%), Positives = 72/174 (41%), Gaps = 5/174 (2%) Frame = +3 Query: 147 DMSIVASDVETGKVIARLDDAHGDAINRLVCLT--ETTVASGDDAGCIKVWDTRQRSCCN 320 D+ + S+ G+ + + + CL + + SG IK+WD C Sbjct: 215 DIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLK 274 Query: 321 TFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKN 497 H + + Y ++++ T S D T+ V + V + + +L L N Sbjct: 275 VLTGHTGSVLCLQY---DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHL-RFSN 330 Query: 498 GQKVVCGTPSGALLLYSWGHFKDCSDR--FLGHAQSVDNLLKLDEETLISAAAD 653 G V C + ++ ++ D + R +GH +V N++ D++ ++SA+ D Sbjct: 331 GLMVTC-SKDRSIAVWDMASATDITLRRVLVGHRAAV-NVVDFDDKYIVSASGD 382 Score = 32.0 bits (71), Expect = 1.7 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQ 305 VI+TGS+D ++ DV TG+V+ L H +A+ L V D I VWD Sbjct: 292 VIVTGSSDSTVRVWDVNTGEVLNTLIH-HNEAVLHLRFSNGLMVTCSKDRS-IAVWDMAS 349 Query: 306 RSCCNTFHRHEDYISDMTYVAGSDQ-ILATSGDGTLSV 416 + + + + V D+ I++ SGD T+ V Sbjct: 350 ATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKV 387 Score = 30.8 bits (68), Expect = 3.7 Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 2/118 (1%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT--ETT 254 H+ + V F D I++ S D +I T + + L+ H I CL + Sbjct: 362 HRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLN-GHKRGI---ACLQYRDRL 415 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 V SG I++WD +C HE+ + + + + +I++ + DG + V L+ Sbjct: 416 VVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQ 471
>TRAF7_HUMAN (Q6Q0C0) E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF| receptor-associated factor 7) (Ring finger and WD repeat domain 1) (RING finger protein 119) Length = 670 Score = 33.5 bits (75), Expect = 0.57 Identities = 26/114 (22%), Positives = 48/114 (42%) Frame = +3 Query: 120 GTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDT 299 G ++ +GS+D +I D T + + H D I +C+ + SG I VWD Sbjct: 408 GDLLFSGSSDKTIKVWDTCTTYKCQKTLEGH-DGIVLALCIQGCKLYSGSADCTIIVWDI 466 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFS 461 + NT H++ + + S +L + + V + G +K + E + Sbjct: 467 QNLQKVNTIRAHDNPVCTL---VSSHNVLFSGSLKAIKVWDIVGTELKLKKELT 517
>VPS15_YEAST (P22219) Serine/threonine-protein kinase VPS15 (EC 2.7.11.1)| (Vacuolar protein sorting protein 15) (Golgi-retention defective mutant protein 8) Length = 1453 Score = 33.5 bits (75), Expect = 0.57 Identities = 25/113 (22%), Positives = 50/113 (44%), Gaps = 7/113 (6%) Frame = +3 Query: 180 GKVIARLDDAHGDAINRLVCLTETT--VASGDDAGCIKVWDTRQRSCCNTFHRHEDY--- 344 GK+IA L + ++I T + +G D G IK+W+ ++ + Y Sbjct: 1068 GKLIATLMENEPNSITSSAVSPGETPYLITGSDQGVIKIWNLKEIIVGEVYSSSLTYDCS 1127 Query: 345 --ISDMTYVAGSDQILATSGDGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKN 497 ++ +T + D +S DG + V + + +S+ +F E + + +KN Sbjct: 1128 STVTQITMIPNFDAFAVSSKDGQIIVLKVNHYQQESEVKFLNCECIRKINLKN 1180
>KI21B_MOUSE (Q9QXL1) Kinesin family member 21B (Kinesin-like protein KIF6)| Length = 1668 Score = 33.5 bits (75), Expect = 0.57 Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVWDTRQ 305 ++ TGS D S ++ TG+ IA L + ++ C + + + + IKVWD R Sbjct: 1322 LLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYC-SHSGLVFSVSSSYIKVWDIRD 1380 Query: 306 RS-CCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSL 425 + C T IS +A S + + TS G +N + Sbjct: 1381 SAKCIRTLTSSGQVISGDACIATSTRAI-TSAQGEHQINQM 1420
>GRWD1_MOUSE (Q810D6) Glutamate-rich WD repeat-containing protein 1 (Protein| A301) Length = 446 Score = 33.5 bits (75), Expect = 0.57 Identities = 31/99 (31%), Positives = 44/99 (44%), Gaps = 7/99 (7%) Frame = +3 Query: 123 TVILTGSADMSIVASDVET--GKV-IARLDDAHGDAINRLV-CLTETTVASGDDAGCIKV 290 TV + SAD SI D+ GK + AH +N + E + SG D G +KV Sbjct: 275 TVFASCSADASIRIWDIRAAPGKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKV 334 Query: 291 WDTRQ---RSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 WD RQ S TF +H ++ + + + A SG Sbjct: 335 WDLRQFKSGSPVATFKQHMAPVTSVEWHPQDSGVFAASG 373
>GRWD1_RAT (Q5XI13) Glutamate-rich WD repeat-containing protein 1| Length = 445 Score = 33.1 bits (74), Expect = 0.74 Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 7/99 (7%) Frame = +3 Query: 123 TVILTGSADMSIVASDVET--GKVIARLDDAHGDAINRLVCLT--ETTVASGDDAGCIKV 290 TV + SAD SI D+ GK A D ++ + E + SG D G +KV Sbjct: 274 TVFASCSADASIRIWDIRAAPGKACMLTTAAAHDGDVNVISWSRREPFLLSGGDDGTLKV 333 Query: 291 WDTRQ---RSCCNTFHRHEDYISDMTYVAGSDQILATSG 398 WD RQ S TF +H ++ + + + A SG Sbjct: 334 WDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASG 372
>DYIN_DICDI (P54703) Dynein intermediate chain, cytosolic (DH IC) (Cytoplasmic| dynein intermediate chain) Length = 652 Score = 33.1 bits (74), Expect = 0.74 Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 3/105 (2%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILAT-SGDGTLSVNSLRG 431 ++S D C K+W +++ + +F + DY+ D + I +T G GTLS+ L Sbjct: 512 LSSSTDWTC-KLWSSKKETPLYSFEDYVDYVYDARWSPVHPSIFSTGDGSGTLSLWDLNQ 570 Query: 432 NRVKS--QSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSWGHF 560 + + + S + L +G++++ G G+L L+ F Sbjct: 571 DLEGPIFRHKISNRSVNRLAWSHDGKRILVGDSGGSLSLFDSSEF 615
>RBBP7_BRARE (Q7ZTY4) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 426 Score = 33.1 bits (74), Expect = 0.74 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Frame = +3 Query: 204 DAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTYVAGS 374 DAH +N L +E +A+G + +WD R ++F H+D I + + + Sbjct: 270 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHN 329 Query: 375 DQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 + ILA+SG D L+V L + +E +ED L+ + G Sbjct: 330 ETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 372
>WSB1_FUGRU (Q9W5Z5) WD repeat and SOCS box-containing protein 1 (WSB-1)| Length = 427 Score = 33.1 bits (74), Expect = 0.74 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVA-GSDQILATSGDGTLSVNSLR- 428 +A+G + G IK+WD + H D + D+T+ GS +++ S D L V L+ Sbjct: 148 LATGLNNGRIKIWDVYTGTLLLNLMDHTDIVRDLTFAPDGSLMLVSASTDKKLRVWDLKD 207 Query: 429 -GNRVK 443 GN VK Sbjct: 208 DGNMVK 213
>RBBP7_CHICK (Q9I8G9) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) Length = 424 Score = 33.1 bits (74), Expect = 0.74 Identities = 42/158 (26%), Positives = 70/158 (44%), Gaps = 10/158 (6%) Frame = +3 Query: 204 DAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTYVAGS 374 DAH +N L +E +A+G + +WD R ++F H+D I + + + Sbjct: 268 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHN 327 Query: 375 DQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNGQKVVCGTPSGALLLYSW 551 + ILA+SG D L+V L + +E +ED L+ + G + + +SW Sbjct: 328 ETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGH-------TAKISDFSW 380 Query: 552 GHFKD---CS---DRFLGHAQSVDNLLKLDEETLISAA 647 + CS D + Q +N+ DEE I+AA Sbjct: 381 NPNEPWVICSVSEDNIMQIWQMAENIYN-DEEPDIAAA 417
>GBB_NICPL (P93339) Guanine nucleotide-binding protein beta subunit (NpGPB1)| Length = 377 Score = 33.1 bits (74), Expect = 0.74 Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 8/134 (5%) Frame = +3 Query: 51 PLERLFA-EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETG---KVIARLDDAHGD 218 P+ R+ + K + SC+ V D T ++T S D + V D+ TG V Sbjct: 147 PVSRMLSGHKGYVSSCQYVP--DEDTHLITSSGDQTCVLWDITTGLRTSVFGGEFQFGHT 204 Query: 219 AINRLVCLTETT---VASGDDAGCIKVWDTRQRSCCN-TFHRHEDYISDMTYVAGSDQIL 386 A + V ++ + SG ++WDTR S TF+ HE ++ + + ++ Sbjct: 205 ADVQSVSISSSNPRLFVSGSCDTTARLWDTRVASRAQRTFYCHEGDVNTVKFFPDGNRFG 264 Query: 387 ATSGDGTLSVNSLR 428 S DGT + +R Sbjct: 265 TGSEDGTCRLFDIR 278
>WDR71_HUMAN (Q9BRP4) WD-repeat protein 71 (Protein G-16)| Length = 392 Score = 33.1 bits (74), Expect = 0.74 Identities = 17/51 (33%), Positives = 23/51 (45%) Frame = +3 Query: 255 VASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGT 407 V SG +K+W SC TF H+ I D V +++ S DGT Sbjct: 149 VLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGT 199
>YGA4_YEAST (P53196) Hypothetical 46.4 kDa Trp-Asp repeats-containing protein| in PMC1-TFG2 intergenic region Length = 417 Score = 32.7 bits (73), Expect = 0.97 Identities = 23/108 (21%), Positives = 45/108 (41%), Gaps = 3/108 (2%) Frame = +3 Query: 72 EKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTET 251 ++ H ++F SG +++ S DM + V+ G L + + Sbjct: 132 DQAHVSEITKLKFFPSGEALISSSQDMQLKIWSVKDGSNPRTLIGHRATVTDIAIIDRGR 191 Query: 252 TVASGDDAGCIKVWDTRQRSCCNTFHRHE---DYISDMTYVAGSDQIL 386 V S G I++W+ + +TF+R E D ++ + G+D+ L Sbjct: 192 NVLSASLDGTIRLWECGTGTTIHTFNRKENPHDGVNSIALFVGTDRQL 239 Score = 31.6 bits (70), Expect = 2.2 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 2/97 (2%) Frame = +3 Query: 126 VILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLT--ETTVASGDDAGCIKVWDT 299 ++ T D+ ++ S+ + I D AH I +L E ++S D +K+W Sbjct: 110 ILGTTEGDIKVLDSNFNLQREI---DQAHVSEITKLKFFPSGEALISSSQDMQ-LKIWSV 165 Query: 300 RQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 + S T H ++D+ + +L+ S DGT+ Sbjct: 166 KDGSNPRTLIGHRATVTDIAIIDRGRNVLSASLDGTI 202
>RBBP7_XENTR (Q6P315) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 32.7 bits (73), Expect = 0.97 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Frame = +3 Query: 204 DAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTYVAGS 374 DAH +N L +E +A+G + +WD R ++F H+D I + + + Sbjct: 269 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHN 328 Query: 375 DQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 + ILA+SG D L+V L + +E +ED L+ + G Sbjct: 329 ETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 371
>RBBP7_XENLA (Q8AVH1) Histone-binding protein RBBP7 (Retinoblastoma-binding| protein 7) (RBBP-7) Length = 425 Score = 32.7 bits (73), Expect = 0.97 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Frame = +3 Query: 204 DAHGDAINRLVC--LTETTVASGDDAGCIKVWDTRQRSC-CNTFHRHEDYISDMTYVAGS 374 DAH +N L +E +A+G + +WD R ++F H+D I + + + Sbjct: 269 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHN 328 Query: 375 DQILATSG-DGTLSVNSLRGNRVKSQSEFSEDELLSLVIMKNG 500 + ILA+SG D L+V L + +E +ED L+ + G Sbjct: 329 ETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGG 371
>TBL1X_HUMAN (O60907) F-box-like/WD-repeat protein TBL1X (Transducin beta-like| 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55) Length = 526 Score = 32.7 bits (73), Expect = 0.97 Identities = 23/105 (21%), Positives = 49/105 (46%) Frame = +3 Query: 114 DSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVW 293 +S ++ + S D ++ D+E G L + +ASG C+ +W Sbjct: 422 NSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIW 481 Query: 294 DTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 +T+ + +++ R I ++ + A D++ A++ DG++ V LR Sbjct: 482 NTQSGNLVHSY-RGTGGIFEVCWNARGDKVGASASDGSVCVLDLR 525 Score = 29.6 bits (65), Expect = 8.2 Identities = 26/133 (19%), Positives = 56/133 (42%), Gaps = 11/133 (8%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCL------ 242 H + A+++ SG ++ + S DM++ ++ I L AH I + Sbjct: 360 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQ-AHNKEIYTIKWSPTGPAT 418 Query: 243 ----TETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTL 410 + +AS +++WD + C +T +H++ + + + + + S D + Sbjct: 419 SNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCV 478 Query: 411 SV-NSLRGNRVKS 446 + N+ GN V S Sbjct: 479 HIWNTQSGNLVHS 491
>POP2_SCHPO (O14170) WD-repeat protein pop2 (Proteolysis factor sud1)| Length = 703 Score = 32.7 bits (73), Expect = 0.97 Identities = 29/128 (22%), Positives = 57/128 (44%) Frame = +3 Query: 57 ERLFAEKPHKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLV 236 E L+ + H +V + + ++GS D SI D+ TG L+ DA L+ Sbjct: 538 ECLYHLRGHSLRIYSVLYEPERNICISGSMDKSIRVWDLSTGTCKYVLEGH--DAFVTLL 595 Query: 237 CLTETTVASGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSV 416 + + + SG I++WD + YIS ++V+ +I+ + DG++ + Sbjct: 596 NVFQNRLISGSADSTIRIWDLNTGKPLMVLPSNSGYIS--SFVSDEHKII-SGNDGSVKL 652 Query: 417 NSLRGNRV 440 +R ++ Sbjct: 653 WDVRTGKL 660
>TB1RA_XENLA (Q7SZM9) F-box-like/WD-repeat-containing protein TBL1XR1-A| (Transducin beta-like 1X-related protein 1-A) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) Length = 519 Score = 32.7 bits (73), Expect = 0.97 Identities = 23/105 (21%), Positives = 50/105 (47%) Frame = +3 Query: 114 DSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVASGDDAGCIKVW 293 ++ ++ + S D ++ DV+ G I L + +ASG C+ +W Sbjct: 415 NANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIW 474 Query: 294 DTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 +T+ + +++ R I ++ + A D++ A++ DG++ V LR Sbjct: 475 NTQTGALVHSY-RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLR 518 Score = 32.3 bits (72), Expect = 1.3 Identities = 26/116 (22%), Positives = 49/116 (42%) Frame = +3 Query: 81 HKDSCRAVRFVDSGTVILTGSADMSIVASDVETGKVIARLDDAHGDAINRLVCLTETTVA 260 HK A+++ G IL+ D + + D TG+ + A++ + + T A Sbjct: 270 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD-VDWQSNNTFA 328 Query: 261 SGDDAGCIKVWDTRQRSCCNTFHRHEDYISDMTYVAGSDQILATSGDGTLSVNSLR 428 S CI V Q TF H + ++ + + + + + S D TL + S++ Sbjct: 329 SCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMK 384 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 98,361,687 Number of Sequences: 219361 Number of extensions: 2134803 Number of successful extensions: 7039 Number of sequences better than 10.0: 353 Number of HSP's better than 10.0 without gapping: 6211 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6860 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6200242422 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
