ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags15d01 |
|---|---|
| Clone Library Name | barley_pub |
>YQJQ_BACSU (P54554) Hypothetical oxidoreductase yqjQ (EC 1.-.-.-)| Length = 259 Score = 102 bits (253), Expect = 9e-22 Identities = 63/171 (36%), Positives = 101/171 (59%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS G+GE ++ A+ GA ++LSAR ++ L +K I + + E+ P+D+ L Sbjct: 14 ASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEW-SGQCEIFPLDVGR----L 68 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +++ + + S ID +++NA F + L+ T + +KA F VNVFG I T+ + P Sbjct: 69 EDIARVRDQIGS---IDVLINNAGFGIFET-VLDSTLDDMKAMFDVNVFGLIACTKAVLP 124 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 ML++ GH + ++S AGK+ TP +LYSA+KHA+ GY +LR EL GI Sbjct: 125 QMLEQKKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMELSGTGI 175
>DHRS7_MOUSE (Q9CXR1) Dehydrogenase/reductase SDR family member 7 precursor (EC| 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) Length = 338 Score = 96.3 bits (238), Expect = 5e-20 Identities = 65/172 (37%), Positives = 93/172 (54%), Gaps = 6/172 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKH--PDSKVEVLPMDL---SS 198 AS GIGE L+ Q + LG L+LSAR +ELERVK + + + VLP+DL SS Sbjct: 58 ASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLENGNLKEKDILVLPLDLTDTSS 117 Query: 199 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITL 375 E + K V+ ID +++N R +R + ET + K +N GT++L Sbjct: 118 HEAATKAVLQEFGK------IDILVNNGG--RSQRSLVLETNLDVFKELINLNYIGTVSL 169 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 T+ + P M++R G V ++S AG + Y ASKHAL G+F +L SEL Sbjct: 170 TKCVLPHMIERKQGKIVTVNSIAGIASVSLSSGYCASKHALRGFFNALHSEL 221
>DHRS7_HUMAN (Q9Y394) Dehydrogenase/reductase SDR family member 7 precursor (EC| 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) Length = 339 Score = 94.4 bits (233), Expect = 2e-19 Identities = 60/173 (34%), Positives = 93/173 (53%), Gaps = 5/173 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKH--PDSKVEVLPMDLS---S 198 AS GIGE L+ Q + LG L+LSAR ELERVK + + + VLP+DL+ S Sbjct: 58 ASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGS 117 Query: 199 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 E + K V+ ID +++N + + ++ + + + ++N GT++LT Sbjct: 118 HEAATKAVLQEF------GRIDILVNNGGMSQ-RSLCMDTSLDVYRKLIELNYLGTVSLT 170 Query: 379 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCT 537 + + P M++R G V ++S G + P Y ASKHAL G+F LR+EL T Sbjct: 171 KCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELAT 223
>YM71_YEAST (Q05016) Putative oxidoreductase YMR226C (EC 1.-.-.-)| Length = 267 Score = 78.6 bits (192), Expect = 1e-14 Identities = 56/175 (32%), Positives = 90/175 (51%), Gaps = 3/175 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQF--ASLG-AKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 204 AS GIG+ ++++ AS G KLIL+AR E+LE +K I + P++KV V +D++ E Sbjct: 21 ASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQAE 80 Query: 205 KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRL 384 K +K + + F ID +++NA + E ++ F NV I +T+ Sbjct: 81 K-IKPFIENLPQEFKD--IDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQA 137 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + P + G V + S AG+ P ++Y ASK A+ + SLR EL I+ Sbjct: 138 VLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIR 192
>DHBX_ANAPL (O57314) Putative steroid dehydrogenase SPM2 (EC 1.1.1.-)| Length = 312 Score = 72.4 bits (176), Expect = 8e-13 Identities = 51/176 (28%), Positives = 86/176 (48%), Gaps = 5/176 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ + + A G K+ L +R+KE+L++V I ++ + +V+ D E Sbjct: 56 ATDGIGKAYAKELAKRGMKVALISRSKEKLDQVAGEITEQY-GVETKVIVADFGEREDIY 114 Query: 214 KEVVHSAESL-----FSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 + E L ++ GI Y + P + ++ + +N+ +T Sbjct: 115 DRIRAGLEGLEIGVLVNNVGISYSYPEYFIDVP------DLDKTIDKMININIMSVCKMT 168 Query: 379 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 RL+ P ML+R G + +SSAAG PTP LYSASK ++ + L +E +KGI Sbjct: 169 RLVLPGMLERSKGVILNISSAAGMYPTPLLTLYSASKAFVDYFSRGLHAEYKSKGI 224
>Y945_MYCTU (P71564) Putative oxidoreductase Rv0945/MT0971 (EC 1.-.-.-)| Length = 253 Score = 72.4 bits (176), Expect = 8e-13 Identities = 52/176 (29%), Positives = 83/176 (47%), Gaps = 4/176 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS G+G ++ FA+ G L L AR + L +K + ++PD K+ V +D++ E+ Sbjct: 15 ASSGLGAGMARSFAAQGRDLALCARRTDRLTELKAELSQRYPDIKIAVAELDVNDHERVP 74 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKR---GALEETEEGLKATFKVNVFGTITLTRL 384 K ++ + GID ++ NA + R G L KAT + N+ + Sbjct: 75 KVFAELSDEI---GGIDRVIVNAGIGKGARLGSGKLWAN----KATIETNLVAALVQIET 127 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPG-QALYSASKHALNGYFASLRSELCTKGIK 549 RG GH V++SS G PG +A Y+ASK + SLR+E + I+ Sbjct: 128 ALDMFNQRGSGHLVLISSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIR 183
>DHI1_HUMAN (P28845) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 291 Score = 70.9 bits (172), Expect = 2e-12 Identities = 52/165 (31%), Positives = 83/165 (50%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG ++ A +GA ++++AR+KE L++V + + S + D Sbjct: 41 ASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIA--GTMEDMTFA 98 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ V A L G+D ++ N + ++ + +VN + LT P Sbjct: 99 EQFVAQAGKLMG--GLDMLILNH-ITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALP 155 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 ML + G VV+SS AGKV P A YSASK AL+G+F+S+R E Sbjct: 156 -MLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKE 199
>DHI1_SHEEP (P51975) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 291 Score = 70.5 bits (171), Expect = 3e-12 Identities = 53/165 (32%), Positives = 85/165 (51%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG ++ A +GA ++++AR++E L++V + S V + Sbjct: 41 ASKGIGREMAYHLARMGAHVVVTARSEESLKKVVSRCLELGAASAHYVA--GTMENMTFA 98 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ V A L G+D ++ N P R L+ + +VN+ + L+ P Sbjct: 99 EQFVAKAGELVG--GLDMLILNHINYTPLR-VFSNDIHLLRRSLEVNLLSYVVLSTAALP 155 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 ML + G VV+SS AGK+ P A YSASK AL+G+F+SLR+E Sbjct: 156 -MLKQTSGSIVVVSSVAGKIACPLAAAYSASKFALDGFFSSLRTE 199
>DHBK_MOUSE (O70503) Putative steroid dehydrogenase KIK-I (EC 1.1.1.-)| Length = 312 Score = 70.5 bits (171), Expect = 3e-12 Identities = 46/171 (26%), Positives = 91/171 (53%), Gaps = 3/171 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG+ + + A G K++L +R++++L +V +NI K + + + +D S D+ + Sbjct: 61 GIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKF-NVETRTIAVDFSLDD-----I 114 Query: 223 VHSAESLFSSAGIDYMMHNA--AFERPKRGA-LEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ S I +++N ++E P+ + + + +K +NV +TRL+ P Sbjct: 115 YDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLP 174 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M++R G + +SSA+G +P P +YSA+K ++ + L E +KGI Sbjct: 175 GMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGI 225
>DHRS8_PONPY (Q5NVG2) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) Length = 300 Score = 70.1 bits (170), Expect = 4e-12 Identities = 53/172 (30%), Positives = 78/172 (45%), Gaps = 6/172 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE--- 204 A GIG + + +FA L +KL+L NK LE K +KV +D S+ E Sbjct: 44 AGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC--KGLGAKVHTFVVDCSNREDIY 101 Query: 205 ---KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 K +K + L ++AG+ Y A + P+ ++ TF+VNV Sbjct: 102 SAAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQ----------IEKTFEVNVLAHFWT 151 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 T+ P M+ GH V ++SAAG V P Y +SK A G+ +L EL Sbjct: 152 TKAFLPAMMKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDEL 203
>FABG_THEMA (Q9X248) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 69.3 bits (168), Expect = 7e-12 Identities = 52/183 (28%), Positives = 89/183 (48%) Frame = +1 Query: 1 RHEARLCG*RXASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 180 R E ++C A+ GIG+ ++ FA GA +I +KE L+ + ++ KV+ Sbjct: 2 RLEGKVCLITGAASGIGKATTLLFAQEGATVIAGDISKENLDSLVKE--AEGLPGKVDPY 59 Query: 181 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVF 360 ++++ D +KEVV + ID +++NA R + EE A VN+ Sbjct: 60 VLNVT-DRDQIKEVVEKVVQKYGR--IDVLVNNAGITRDAL-LVRMKEEDWDAVINVNLK 115 Query: 361 GTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTK 540 G +T+++ P+M+ + G V +SS G PGQ Y+ASK + G + EL + Sbjct: 116 GVFNVTQMVVPYMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGR 175 Query: 541 GIK 549 I+ Sbjct: 176 NIR 178
>Y452_LISIN (Q92EK7) Hypothetical oxidoreductase Lin0452 (EC 1.-.-.-)| Length = 248 Score = 68.9 bits (167), Expect = 9e-12 Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 4/174 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIGE ++ A GAKL+L+AR E+LE++ I + ++ + D K L Sbjct: 13 ASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQTIKASSGEAIFAKTDVTKREDNKKL 72 Query: 214 KEVV----HSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 E+ +++F +AGI M N+ AL+E E + +N+ G + Sbjct: 73 VELAIERYGKVDAIFLNAGI---MPNSPL-----SALKEDE--WEQMIDINIKGVLNGIA 122 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 + P + + GH + SS AG PG A+Y A+K A+ LR E +G Sbjct: 123 AVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEG 176
>DHRS8_HUMAN (Q8NBQ5) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) (Retinal short-chain dehydrogenase/reductase 2) (re Length = 300 Score = 68.9 bits (167), Expect = 9e-12 Identities = 53/172 (30%), Positives = 77/172 (44%), Gaps = 6/172 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE--- 204 A GIG + + +FA L +KL+L NK LE K +KV +D S+ E Sbjct: 44 AGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC--KGLGAKVHTFVVDCSNREDIY 101 Query: 205 ---KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 K +K + L ++AG+ Y A + P+ ++ TF+VNV Sbjct: 102 SSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQ----------IEKTFEVNVLAHFWT 151 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 T+ P M GH V ++SAAG V P Y +SK A G+ +L EL Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDEL 203
>DHRS8_MOUSE (Q9EQ06) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) Length = 298 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/174 (28%), Positives = 75/174 (43%), Gaps = 4/174 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM----DLSSD 201 A GIG + + +FA L KL+L NK +E + V+ ++ S Sbjct: 44 AGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQAHPFVVDCSQREEIYSA 103 Query: 202 EKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 K +KE V L ++AG+ Y A + P+ ++ TF+VNV T+ Sbjct: 104 AKKVKEEVGDVSILVNNAGVVYTADLFATQDPQ----------IEKTFEVNVLAHFWTTK 153 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 P M+ GH V ++SAAG P Y +SK A G+ +L EL G Sbjct: 154 AFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALG 207
>Y432_LISMO (P25145) Hypothetical oxidoreductase Lmo0432 (EC 1.-.-.-) (ORFA)| Length = 248 Score = 67.8 bits (164), Expect = 2e-11 Identities = 51/174 (29%), Positives = 82/174 (47%), Gaps = 4/174 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIG+ ++ A GAKL+L+AR E+LE++ I + ++ + D K L Sbjct: 13 ASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQTIKANSGEAIFAKTDVTKREDNKKL 72 Query: 214 KEVV----HSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 E+ +++F +AGI M N+ AL+E E + +N+ G + Sbjct: 73 VELAIERYGKVDAIFLNAGI---MPNSPLS-----ALKEDE--WEQMIDINIKGVLNGIA 122 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 + P + + GH + SS AG PG A+Y A+K A+ LR E +G Sbjct: 123 AVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEG 176
>DHI1_SAISC (Q29608) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 290 Score = 67.8 bits (164), Expect = 2e-11 Identities = 50/165 (30%), Positives = 82/165 (49%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG ++ A +GA ++++AR+KE L++V + + S + D Sbjct: 41 ASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIA--GTMEDMTFA 98 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ V A L G+D ++ N + ++ + +VN + LT P Sbjct: 99 EQFVAQAGKLMG--GLDMLILNH-ITNTSLNFFHDDIHHVRKSMEVNFLSYVVLTVAAMP 155 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 ML + G V++SS AGKV P + YSASK AL G+F+S+R E Sbjct: 156 -MLKQSNGSIVIVSSVAGKVAYPMISAYSASKFALYGFFSSIRKE 199
>YUSZ_BACSU (P37959) Hypothetical oxidoreductase yusZ (EC 1.-.-.-) (ORFA)| Length = 280 Score = 67.4 bits (163), Expect = 3e-11 Identities = 49/173 (28%), Positives = 92/173 (53%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS G G + +++ A +I ++R E+ E+++ + + + + +D++ DE+S Sbjct: 11 ASSGFGLLAAVKLAR-SFFVIATSRQPEKAEQLRELAAAHNVSDSIHITALDVT-DEQS- 67 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLLA 390 +V +++ + A ID +++NA G +E+ E + F+ NVFG I +T+ + Sbjct: 68 --IVSFGKAVSAYAPIDLLVNNAG--TAYGGFIEDVPMEHFRQQFETNVFGVIHVTKTVL 123 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P++ G + +SS +G P + Y +SKHAL G+ SLR EL GI+ Sbjct: 124 PYIRKHGGAKIINVSSISGLTGFPALSPYVSSKHALEGFSESLRIELLPFGIE 176
>DHI1_CAVPO (Q6QLL4) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 299 Score = 67.0 bits (162), Expect = 3e-11 Identities = 51/165 (30%), Positives = 84/165 (50%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG ++ A +GA ++++AR+KE L++V + S + D Sbjct: 41 ASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGS--MEDMTFA 98 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +E V A +L G+D ++ N + + ++ + +VN + L+ P Sbjct: 99 EEFVAEAGNLMG--GLDMLILNHVLYN-RLTFFHGEIDNVRKSMEVNFHSFVVLSVAAMP 155 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 ML + G V+SS AGK+ P A YSASK AL+G+F++LRSE Sbjct: 156 -MLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSE 199
>DHRS8_RAT (Q6AYS8) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) Length = 298 Score = 67.0 bits (162), Expect = 3e-11 Identities = 51/176 (28%), Positives = 77/176 (43%), Gaps = 6/176 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE--- 204 A GIG + + +FA L KL+L NK +E + ++V +D S E Sbjct: 44 AGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKC--RKLGAQVHPFVVDCSQREEIY 101 Query: 205 ---KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 + +KE V L ++AG+ Y A + P+ ++ TF+VNV Sbjct: 102 SAVRKVKEEVGDVSILVNNAGVVYTADLFATQDPQ----------IEKTFEVNVLAHFWT 151 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 T+ P M+ GH V ++SAAG P Y +SK A G+ +L EL G Sbjct: 152 TKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALG 207
>HETN_ANASP (P37694) Ketoacyl reductase hetN (EC 1.3.1.-)| Length = 287 Score = 66.6 bits (161), Expect = 4e-11 Identities = 50/171 (29%), Positives = 86/171 (50%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRG+G ++ A A ++ +R++ L + + + K K +P D+ + + L Sbjct: 14 ASRGLGVYIARALAKEQATVVCVSRSQSGLAQTCNAV--KAAGGKAIAIPFDVRNTSQ-L 70 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +V A+ + ID +++NA E A E +++ F N+ + LTRLL P Sbjct: 71 SALVQQAQDIVGP--IDVLINNAGIEINGTFANYSLAE-IQSIFNTNLLAAMELTRLLLP 127 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M++RG G V ++S AGK ++YSASK L + ++R EL G+ Sbjct: 128 SMMERGSGRIVNIASLAGKKGVAFNSVYSASKAGLIMWTDAMRQELVGTGV 178
>DHRS4_PONPY (Q5RCF8) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 66.2 bits (160), Expect = 6e-11 Identities = 47/169 (27%), Positives = 82/169 (48%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ + A GA +++S+R ++ +++ + + V + + D + L Sbjct: 25 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLV-- 82 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 A ++ GID ++ NAA ++ TEE T +NV +T+ + P M Sbjct: 83 ---ATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEME 139 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G V++SS A P+PG + Y+ SK AL G +L EL + I+ Sbjct: 140 KRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIR 188
>DHRS4_HUMAN (Q9BTZ2) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 66.2 bits (160), Expect = 6e-11 Identities = 47/169 (27%), Positives = 82/169 (48%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ + A GA +++S+R ++ +++ + + V + + D + L Sbjct: 25 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLV-- 82 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 A ++ GID ++ NAA ++ TEE T +NV +T+ + P M Sbjct: 83 ---ATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEME 139 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G V++SS A P+PG + Y+ SK AL G +L EL + I+ Sbjct: 140 KRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIR 188
>DHI1_MESAU (Q6R0J2) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (7-alpha-hydroxycholesterol dehydrogenase) (7-alpha-HCD) Length = 291 Score = 65.5 bits (158), Expect = 1e-10 Identities = 51/165 (30%), Positives = 82/165 (49%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG ++ + +GA ++L+AR++E L++V + S + D Sbjct: 41 ASKGIGREMAYHLSEMGAHVVLTARSEEGLQKVASRCLELGAASAHYIA--GTMEDMTFA 98 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ V A L G+D ++ N +E L+ +VN + ++ P Sbjct: 99 EQFVLKAGKLMG--GLDMLILNHITYTSMNFFRDEIH-ALRKAMEVNFISYVVMSVAALP 155 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 ML + G VV+SS AGK+ P A YSASK AL+G+F+SLR E Sbjct: 156 -MLKQSNGSIVVVSSIAGKMAHPLVASYSASKFALDGFFSSLRRE 199
>DHRS4_RAT (Q8VID1) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) (N Length = 260 Score = 64.7 bits (156), Expect = 2e-10 Identities = 46/169 (27%), Positives = 79/169 (46%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ + A GA +++S+R ++ ++R + + V + + D + L + Sbjct: 25 GIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCHVGKAEDREKLVNM 84 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 +L GID ++ NAA ++ TEE +NV + + + + P M Sbjct: 85 -----ALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMIKAVVPAME 139 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G V++SS AG V P Y+ SK AL G + +EL K I+ Sbjct: 140 KRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIR 188
>DHRS4_PIG (Q8WNV7) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) (N Length = 260 Score = 64.7 bits (156), Expect = 2e-10 Identities = 46/169 (27%), Positives = 79/169 (46%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ + A GA +++S+R +E ++R + + V + + D + L Sbjct: 25 GIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKAEDRERLV-- 82 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 A ++ G+D ++ NAA ++ TEE VNV T+ +T+ + P M Sbjct: 83 ---AMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEME 139 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G +++SS P P Y+ SK AL G +L EL + I+ Sbjct: 140 KRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIR 188
>FABG_STAAW (P0A0I0) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 64.3 bits (155), Expect = 2e-10 Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPMDLSSDEK 207 ASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ D + Sbjct: 12 ASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKA 71 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +KEVV SL D +++NA R + E+ N+ G + Sbjct: 72 MIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177
>FABG_STAAS (Q6G9Y2) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 64.3 bits (155), Expect = 2e-10 Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPMDLSSDEK 207 ASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ D + Sbjct: 12 ASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKA 71 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +KEVV SL D +++NA R + E+ N+ G + Sbjct: 72 MIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177
>FABG_STAAR (Q6GHK4) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 64.3 bits (155), Expect = 2e-10 Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPMDLSSDEK 207 ASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ D + Sbjct: 12 ASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKA 71 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +KEVV SL D +++NA R + E+ N+ G + Sbjct: 72 MIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177
>FABG_STAAN (P99093) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 64.3 bits (155), Expect = 2e-10 Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPMDLSSDEK 207 ASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ D + Sbjct: 12 ASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKA 71 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +KEVV SL D +++NA R + E+ N+ G + Sbjct: 72 MIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177
>FABG_STAAM (P0A0H9) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 64.3 bits (155), Expect = 2e-10 Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPMDLSSDEK 207 ASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ D + Sbjct: 12 ASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKA 71 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +KEVV SL D +++NA R + E+ N+ G + Sbjct: 72 MIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177
>FABG_STAAC (Q5HGK2) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 64.3 bits (155), Expect = 2e-10 Identities = 53/173 (30%), Positives = 80/173 (46%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDS-KVEVLPMDLSSDEK 207 ASRGIG +++Q A G + ++ A +KE+ E V I +K DS ++ D + Sbjct: 12 ASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKA 71 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +KEVV SL D +++NA R + E+ N+ G + Sbjct: 72 MIKEVVSQFGSL------DVLVNNAGITRDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + +SS G V PGQA Y A+K + G S EL ++GI Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177
>DHI1_RABIT (Q7M3I4) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 291 Score = 64.3 bits (155), Expect = 2e-10 Identities = 50/165 (30%), Positives = 82/165 (49%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG+ ++ A +GA ++++AR+KE L+ V + + S + D Sbjct: 41 ASKGIGKEIAFHLAKMGAHVVVTARSKETLQEVVAHCLKLGAASAHYIA--GTMEDMTFA 98 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ V A L G+D ++ N + ++ +VN + LT P Sbjct: 99 EQFVAKAGKLMG--GLDMLILNHITNASLMFFNNDIHH-VRKEMEVNFLSYVVLTVAALP 155 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 ML + G VV+SS AGK+ P A YSASK AL+G+F+++R E Sbjct: 156 -MLKQSNGSIVVVSSLAGKIAHPLIAPYSASKFALDGFFSAIRKE 199
>DHI1_MOUSE (P50172) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A) Length = 291 Score = 64.3 bits (155), Expect = 2e-10 Identities = 46/166 (27%), Positives = 83/166 (50%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG ++ + +GA ++L+AR++E L++V + S + D Sbjct: 41 ASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIA--GTMEDMTFA 98 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ + A L G+D ++ N + + ++ +VN + ++ P Sbjct: 99 EQFIVKAGKLMG--GLDMLILNH-ITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALP 155 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 ML + G V+SS AGK+ P A YSASK AL+G+F+++R+EL Sbjct: 156 -MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 200
>DHRS8_MACFA (Q4JK73) Dehydrogenase/reductase SDR family member 8 precursor (EC| 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase 11) (17-beta-HSD 11) (17-beta-HSD XI) (17betaHSDXI) (17bHSD11) (17betaHSD11) Length = 300 Score = 64.3 bits (155), Expect = 2e-10 Identities = 49/172 (28%), Positives = 77/172 (44%), Gaps = 6/172 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE--- 204 A GIG + + +FA L +KL+L NK LE K +KV +D S+ E Sbjct: 44 AGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC--KGLGAKVYTFVVDCSNREDIY 101 Query: 205 ---KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 K +K + L ++AG+ Y A + + ++ TF+VN+ Sbjct: 102 SSAKKVKAEIGDVSILVNNAGVVYTSDLFATQ----------DAQIEKTFEVNILAHFWT 151 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 T+ P M+ GH V ++SAAG + P Y +SK + G+ +L EL Sbjct: 152 TKAFLPAMMKNNHGHVVTVASAAGHISVPFLLAYCSSKFSAVGFHKALTDEL 203
>Y4EK_RHISN (P55434) Putative short-chain type dehydrogenase/reductase y4eK (EC| 1.-.-.-) Length = 248 Score = 64.3 bits (155), Expect = 2e-10 Identities = 40/166 (24%), Positives = 79/166 (47%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIG+ ++++ AS G +++ R++ L+ + H + + + DLS Sbjct: 15 ASSGIGKAIALELASAGLRVLALGRDRAALDEL-------HSTAGIVPVVFDLSD----- 62 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 V + ID +++NA ++ +E+ + A +N+ LTR + Sbjct: 63 ---VSEVYGKIAGEKIDVLVNNAGLLTASASLVDLSEDDIDAMIDINIRSVFKLTRHVLK 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M++R GH S+ G P P ++Y A+K A++ + ++LR +L Sbjct: 120 QMIERRRGHIFFTGSSGGLAPHPNSSVYGATKAAVSLFSSALRCDL 165
>YDFG_ECOL6 (Q8FHD2) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 63.9 bits (154), Expect = 3e-10 Identities = 42/166 (25%), Positives = 85/166 (51%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G GE ++ +F G K+I + R +E L+ +K + ++++V + ++ Sbjct: 8 ATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDV------RNRAAI 61 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +E++ S + +S+ ID +++NA A + + E + N G + +TR + P Sbjct: 62 EEMLASLPAEWSN--IDILVNNAGLALGMEPAHKASIEDWETMIDTNNKGLVYMTRAVLP 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M++R GH + + S AG P G +Y A+K + + +LR++L Sbjct: 120 GMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDL 165
>DHBA_BACSU (P39071) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC| 1.3.1.28) (Cold shock protein CSI14) Length = 261 Score = 63.9 bits (154), Expect = 3e-10 Identities = 52/173 (30%), Positives = 82/173 (47%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A++GIGE ++ AS GA + N E+LE+V ++ K E P D+ D ++ Sbjct: 16 AAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSL--KAEARHAEAFPADVR-DSAAI 72 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTITLTRLLA 390 E+ E ID +++ A RP G + ++E +ATF VN G +R ++ Sbjct: 73 DEITARIER--EMGPIDILVNVAGVLRP--GLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +M+DR G V + S VP A Y++SK A + L EL I+ Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181
>DHB13_MOUSE (Q8VCR2) 17-beta hydroxysteroid dehydrogenase 13 precursor (EC| 1.1.-.-) (Short-chain dehydrogenase/reductase 9) (Alcohol dehydrogenase PAN1B-like) Length = 304 Score = 63.5 bits (153), Expect = 4e-10 Identities = 49/171 (28%), Positives = 81/171 (47%), Gaps = 1/171 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A GIG + + +FA ++L+L NK +E + + V V +D S+ Sbjct: 44 AGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKC--RKLGAVVHVFVVDCSNRA--- 98 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 E+ +S + + G ++ +++NA P L +E + TF+VN+ G + + L Sbjct: 99 -EIYNSVDQVKREVGDVEIVVNNAGAIYPA-DLLSAKDEEITKTFEVNILGHFWIIKALL 156 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 P ML R GH V ++S G P Y +SK A G+ +L +EL T G Sbjct: 157 PSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLG 207
>DHI1_RAT (P16232) Corticosteroid 11-beta-dehydrogenase isozyme 1 (EC| 1.1.1.146) (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) Length = 288 Score = 63.2 bits (152), Expect = 5e-10 Identities = 50/172 (29%), Positives = 89/172 (51%), Gaps = 3/172 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM--DLSSDEK 207 AS+GIG ++ + +GA ++L+AR++E L++V + S + D++ E+ Sbjct: 38 ASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAER 97 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 VV + + L G+D ++ N + + ++ + +VN + L+ Sbjct: 98 F---VVEAGKLL---GGLDMLILNH-ITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAA 150 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE-LCTK 540 P ML + G ++SS AGK+ P A YSASK AL+G+F+++R E L TK Sbjct: 151 LP-MLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTK 201
>FVT1_MOUSE (Q6GV12) 3-ketodihydrosphingosine reductase precursor (EC| 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1) Length = 332 Score = 62.8 bits (151), Expect = 6e-10 Identities = 47/168 (27%), Positives = 85/168 (50%), Gaps = 3/168 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL--PMDLSSDEKS 210 S GIG+ ++++ GA + L ARN+++L + K +I + K VL +D+S D Sbjct: 41 SSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKDIEKHSINDKQVVLCISVDVSQDYNQ 100 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLL 387 ++ V+ A+ +D +++ A G EE E + +N G++ +R + Sbjct: 101 VENVIKQAQEKLGP--VDMLVNCAG--TSMSGKFEELEVSSFEKLMSINYLGSVYPSRAV 156 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M +R +G V +SS AG++ G YS+SK A+ G +L+ E+ Sbjct: 157 ITTMKERRVGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQMEV 204
>DHRS4_BOVIN (Q8SPU8) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 62.8 bits (151), Expect = 6e-10 Identities = 46/169 (27%), Positives = 77/169 (45%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ + A GA +++S+R ++ ++R + + V + + D + L Sbjct: 25 GIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCHVGKAEDRERLV-- 82 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 A ++ G+D ++ NAA ++ EE VNV T LT+ + P M Sbjct: 83 ---ATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLTKAVVPEMA 139 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G V++SS A P P Y+ SK AL G +L EL ++ Sbjct: 140 KRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVR 188
>FABG1_SYNY3 (P73574) 3-oxoacyl-[acyl-carrier-protein] reductase 1 (EC| 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase 1) Length = 247 Score = 62.8 bits (151), Expect = 6e-10 Identities = 46/172 (26%), Positives = 91/172 (52%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ ++ A+ G K++++ A++ + V I++ ++ + V ++DE Sbjct: 14 ASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEA-IAVQANVANADE-- 70 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + +++ + FS ID +++NA R L E +A +N+ G T+ ++ Sbjct: 71 VDQLIKTTLDKFSR--IDVLVNNAGITRDTL-LLRMKLEDWQAVIDLNLTGVFLCTKAVS 127 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 ML + G + ++S AG + PGQA YSA+K + G+ ++ EL ++G+ Sbjct: 128 KLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGV 179
>YDFG_SALTY (P69936) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 62.4 bits (150), Expect = 8e-10 Identities = 42/166 (25%), Positives = 82/166 (49%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G GE ++ +F G K+I + R E L+ +K + ++++V + ++ Sbjct: 8 ATAGFGECIARRFVENGHKVIATGRRHERLQALKDELGENVLTAQLDV------RNRAAI 61 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +E++ S + + ID +++NA A + + E + N G I +TR + P Sbjct: 62 EEMMASLPAQWRD--IDVLVNNAGLALGLEPAHKASVEDWETMIDTNNKGLIYMTRAVLP 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M++R GH + + S AG P G +Y A+K + + +LR++L Sbjct: 120 GMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDL 165
>YDFG_SALTI (P69935) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 62.4 bits (150), Expect = 8e-10 Identities = 42/166 (25%), Positives = 82/166 (49%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G GE ++ +F G K+I + R E L+ +K + ++++V + ++ Sbjct: 8 ATAGFGECIARRFVENGHKVIATGRRHERLQALKDELGENVLTAQLDV------RNRAAI 61 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +E++ S + + ID +++NA A + + E + N G I +TR + P Sbjct: 62 EEMMASLPAQWRD--IDVLVNNAGLALGLEPAHKASVEDWETMIDTNNKGLIYMTRAVLP 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M++R GH + + S AG P G +Y A+K + + +LR++L Sbjct: 120 GMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDL 165
>YDFG_ECOLI (P39831) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 62.4 bits (150), Expect = 8e-10 Identities = 41/166 (24%), Positives = 84/166 (50%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G GE ++ +F G K+I + R +E L+ +K + ++++V + ++ Sbjct: 8 ATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDV------RNRAAI 61 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +E++ S + + + ID +++NA A + + E + N G + +TR + P Sbjct: 62 EEMLASLPAEWCN--IDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVLP 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M++R GH + + S AG P G +Y A+K + + +LR++L Sbjct: 120 GMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDL 165
>YBBO_ECOLI (P0AFP4) Hypothetical oxidoreductase ybbO (EC 1.-.-.-)| Length = 269 Score = 62.4 bits (150), Expect = 8e-10 Identities = 52/178 (29%), Positives = 82/178 (46%), Gaps = 7/178 (3%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE---K 207 S GIG +++ G ++ R +++ER+ N M + +DL S E + Sbjct: 24 SSGIGLESALELKRQGFHVLAGCRKPDDVERM--NSMG------FTGVLIDLDSPESVDR 75 Query: 208 SLKEVVHSAES----LFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 + EV+ ++ +F++AG + R + ++ F N FG L Sbjct: 76 AADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQ----------MEQQFSANFFGAHQL 125 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 T L P ML G G V+ SS G + TPG+ Y+ASK+AL + +LR EL GIK Sbjct: 126 TMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIK 183
>YBBO_ECOL6 (P0AFP5) Hypothetical oxidoreductase ybbO (EC 1.-.-.-)| Length = 269 Score = 62.4 bits (150), Expect = 8e-10 Identities = 52/178 (29%), Positives = 82/178 (46%), Gaps = 7/178 (3%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE---K 207 S GIG +++ G ++ R +++ER+ N M + +DL S E + Sbjct: 24 SSGIGLESALELKRQGFHVLAGCRKPDDVERM--NSMG------FTGVLIDLDSPESVDR 75 Query: 208 SLKEVVHSAES----LFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 + EV+ ++ +F++AG + R + ++ F N FG L Sbjct: 76 AADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQ----------MEQQFSANFFGAHQL 125 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 T L P ML G G V+ SS G + TPG+ Y+ASK+AL + +LR EL GIK Sbjct: 126 TMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIK 183
>YDFG_SHIFL (Q83RE8) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 62.0 bits (149), Expect = 1e-09 Identities = 41/166 (24%), Positives = 84/166 (50%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G GE ++ +F G K+I + R +E L+ + + ++++V + ++ Sbjct: 8 ATAGFGECITRRFIQQGHKVIATGRRQERLQELTDELGDNLYIAQLDV------RNRAAI 61 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +E++ S + +S+ ID +++NA A + + E + N G + +TR + P Sbjct: 62 EEMLASLPAEWSN--IDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVLP 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M++R GH + + S AG P G +Y A+K + + +LR++L Sbjct: 120 GMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDL 165
>YDFG_ECO57 (Q8X505) NADP-dependent L-serine/L-allo-threonine dehydrogenase| ydfG (EC 1.1.1.-) Length = 248 Score = 62.0 bits (149), Expect = 1e-09 Identities = 41/166 (24%), Positives = 84/166 (50%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G GE ++ +F G K+I + R +E L+ +K + ++++V + ++ Sbjct: 8 ATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDV------RNRAAI 61 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +E++ S + + + ID +++NA A + + E + N G + +TR + P Sbjct: 62 EEMLASLPAEWCN--IDILVNNAGLALGMEPAHKASIEDWETMIDTNNKGLVYMTRAVLP 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M++R GH + + S AG P G +Y A+K + + +LR++L Sbjct: 120 GMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDL 165
>TRNH1_ARATH (Q9ASX2) Putative tropinone reductase homolog At1g07440 (EC| 1.1.1.-) Length = 266 Score = 61.6 bits (148), Expect = 1e-09 Identities = 49/171 (28%), Positives = 76/171 (44%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++GIG + +FA GA + ARN+ EL K V L + + L Sbjct: 23 TKGIGHAIVEEFAGFGAVIHTCARNEYELNECLSKWQKKGFQVTGSVCDASLRPEREKLM 82 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 + V S+F +D +++N R K L+ T E N+ L++L P Sbjct: 83 QTV---SSMFGGK-LDILINNLGAIRSKP-TLDYTAEDFSFHISTNLESAYHLSQLAHPL 137 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G G+ + MSS AG V ++YSA+K ALN +L E + GI+ Sbjct: 138 LKASGCGNIIFMSSIAGVVSASVGSIYSATKGALNQLARNLACEWASDGIR 188
>DHRS4_MOUSE (Q99LB2) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 61.6 bits (148), Expect = 1e-09 Identities = 45/169 (26%), Positives = 76/169 (44%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ + A GA +++S+R ++ ++R + + V + + D + L Sbjct: 25 GIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCHVGKAEDREKL--- 81 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 +L GID ++ NAA ++ TEE +NV T + + + P M Sbjct: 82 --ITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMIKAVVPEME 139 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G V++ S AG P Y+ SK AL G + +EL K I+ Sbjct: 140 KRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIR 188
>Y1570_MYCBO (P66780) Putative oxidoreductase Mb1570 (EC 1.-.-.-)| Length = 341 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 4/168 (2%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS-KHPDSKVEVLPMDLSSDEKSL 213 S GIG + + A G ++L AR E LE V ++I + + V P DLS + Sbjct: 62 SSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAI- 120 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL---KATFKVNVFGTITLTRL 384 V + + L G+D +++NA R R +LE + + + + T ++N G + L Sbjct: 121 --AVMADQVLGDLGGVDILINNAG--RSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILK 176 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 P M +R GH V +SS + P Y ASK AL+ +L++E Sbjct: 177 FIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAE 224
>Y1543_MYCTU (P66779) Putative oxidoreductase Rv1543/MT1595 (EC 1.-.-.-)| Length = 341 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 4/168 (2%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMS-KHPDSKVEVLPMDLSSDEKSL 213 S GIG + + A G ++L AR E LE V ++I + + V P DLS + Sbjct: 62 SSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAI- 120 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL---KATFKVNVFGTITLTRL 384 V + + L G+D +++NA R R +LE + + + + T ++N G + L Sbjct: 121 --AVMADQVLGDLGGVDILINNAG--RSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILK 176 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 P M +R GH V +SS + P Y ASK AL+ +L++E Sbjct: 177 FIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAE 224
>FVT1_HUMAN (Q06136) 3-ketodihydrosphingosine reductase precursor (EC| 1.1.1.102) (3-dehydrosphinganine reductase) (KDS reductase) (Follicular variant translocation protein 1) (FVT-1) Length = 332 Score = 61.2 bits (147), Expect = 2e-09 Identities = 47/168 (27%), Positives = 84/168 (50%), Gaps = 3/168 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL--PMDLSSDEKS 210 S GIG+ ++++ GA + L ARN+++L + K I + K VL +D+S D Sbjct: 41 SSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQ 100 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLL 387 ++ V+ A+ +D +++ A G E+ E + +N G++ +R + Sbjct: 101 VENVIKQAQEKLGP--VDMLVNCAGM--AVSGKFEDLEVSTFERLMSINYLGSVYPSRAV 156 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 M +R +G V +SS AG++ G YSASK A+ G +L+ E+ Sbjct: 157 ITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEV 204
>UCPA_SALTY (P0A2D1) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 61.2 bits (147), Expect = 2e-09 Identities = 53/174 (30%), Positives = 87/174 (50%), Gaps = 2/174 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSK-HPDSKVEVLPMDLSSDEKS 210 AS+GIGE ++ FA GA LIL + +E+E++ + + H + V+ D +S + + Sbjct: 14 ASQGIGEGIARVFARHGANLILLDIS-DEIEKLADELGGRGHRCTAVKADVRDFASVQAA 72 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + A + + ID +++NA R L+ +EE +N+ G +T+ + Sbjct: 73 V------ARAKETEGRIDILVNNAGVCR-LGNFLDMSEEDRDFHIDINIKGVWNVTKAVL 125 Query: 391 PFMLDRGMGHFVVMSSAAG-KVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P M+ R G V+MSS G V PG+ Y+ SK A+ G SL E GI+ Sbjct: 126 PEMIKRKDGRIVMMSSVTGDMVADPGETAYALSKAAIVGLTKSLAVEYAQSGIR 179
>UCPA_SALTI (P0A2D2) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 61.2 bits (147), Expect = 2e-09 Identities = 53/174 (30%), Positives = 87/174 (50%), Gaps = 2/174 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSK-HPDSKVEVLPMDLSSDEKS 210 AS+GIGE ++ FA GA LIL + +E+E++ + + H + V+ D +S + + Sbjct: 14 ASQGIGEGIARVFARHGANLILLDIS-DEIEKLADELGGRGHRCTAVKADVRDFASVQAA 72 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + A + + ID +++NA R L+ +EE +N+ G +T+ + Sbjct: 73 V------ARAKETEGRIDILVNNAGVCR-LGNFLDMSEEDRDFHIDINIKGVWNVTKAVL 125 Query: 391 PFMLDRGMGHFVVMSSAAG-KVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P M+ R G V+MSS G V PG+ Y+ SK A+ G SL E GI+ Sbjct: 126 PEMIKRKDGRIVMMSSVTGDMVADPGETAYALSKAAIVGLTKSLAVEYAQSGIR 179
>DHB13_RAT (Q5M875) 17-beta hydroxysteroid dehydrogenase 13 precursor (EC| 1.1.-.-) (Short-chain dehydrogenase/reductase 9) Length = 300 Score = 61.2 bits (147), Expect = 2e-09 Identities = 49/171 (28%), Positives = 80/171 (46%), Gaps = 1/171 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A GIG + + +FA ++L+L +K +E + + V V +D S+ Sbjct: 44 AGHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKC--RKLGAVVHVFVVDCSNRA--- 98 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 E+ S + + G I+ +++NA P L +E + TF+VN+ G + + L Sbjct: 99 -EIYKSVDQVKKEVGDIEIVVNNAGAIYPA-DLLSTKDEEITKTFEVNILGHFWIIKALL 156 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 P ML R GH V ++S G P Y +SK A G+ +L +EL T G Sbjct: 157 PSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAELDTLG 207
>DHRS4_RABIT (Q9GKX2) Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (Peroxisomal short-chain alcohol dehydrogenase) (NADPH-dependent retinol dehydrogenase/reductase) Length = 260 Score = 60.1 bits (144), Expect = 4e-09 Identities = 46/169 (27%), Positives = 79/169 (46%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ + A GA +++S+R ++ ++R + ++ V + + D + L Sbjct: 25 GIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCHVGKAEDRERLV-- 82 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 A +L GID ++ NAA ++ TEE +NV +T+ + P M Sbjct: 83 ---ATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMTKAVVPEME 139 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G V+++S A P G Y+ SK AL G +L EL + I+ Sbjct: 140 KRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIR 188
>DHB13_HUMAN (Q7Z5P4) 17-beta hydroxysteroid dehydrogenase 13 precursor (EC| 1.1.-.-) (Short-chain dehydrogenase/reductase 9) Length = 300 Score = 59.7 bits (143), Expect = 5e-09 Identities = 48/171 (28%), Positives = 74/171 (43%), Gaps = 1/171 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A GIG + +FA + L+L NK +E K+ V D + Sbjct: 44 AGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECR------KLGVTAHAYVVDCSNR 97 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 +E+ S + G + +++NA P L +E + TF+VN+ G +T+ L Sbjct: 98 EEIYRSLNQVKKEVGDVTIVVNNAGTVYPA-DLLSTKDEEITKTFEVNILGHFWITKALL 156 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 P M++R GH V ++S G P Y +SK A G+ L SEL G Sbjct: 157 PSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALG 207
>Y1385_MYCBO (P66782) Putative oxidoreductase Mb1385 (EC 1.-.-.-)| Length = 247 Score = 59.7 bits (143), Expect = 5e-09 Identities = 50/171 (29%), Positives = 79/171 (46%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++G+G + +F + GA+++L N E E + D + D++ + + Sbjct: 16 AQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGG---DDVALAVRCDVTQAD-DVD 71 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 ++ +A F G+D M++NA R TEE V++ GT TRL A Sbjct: 72 ILIRTAVERFG--GLDVMVNNAGITRDAT-MRTMTEEQFDQVIAVHLKGTWNGTRLAAAI 128 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M +R G V MSS +GKV GQ YSA+K + G + EL GI+ Sbjct: 129 MRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIR 179
>Y1350_MYCTU (P66781) Putative oxidoreductase Rv1350/MT1393 (EC 1.-.-.-)| Length = 247 Score = 59.7 bits (143), Expect = 5e-09 Identities = 50/171 (29%), Positives = 79/171 (46%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++G+G + +F + GA+++L N E E + D + D++ + + Sbjct: 16 AQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGG---DDVALAVRCDVTQAD-DVD 71 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 ++ +A F G+D M++NA R TEE V++ GT TRL A Sbjct: 72 ILIRTAVERFG--GLDVMVNNAGITRDAT-MRTMTEEQFDQVIAVHLKGTWNGTRLAAAI 128 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M +R G V MSS +GKV GQ YSA+K + G + EL GI+ Sbjct: 129 MRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIR 179
>YGHA_ECOLI (P0AG84) Hypothetical oxidoreductase yghA (EC 1.-.-.-)| Length = 294 Score = 59.3 bits (142), Expect = 7e-09 Identities = 50/169 (29%), Positives = 77/169 (45%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ +A GA + +S EE + + + K +LP DLS DEK + + Sbjct: 60 GIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLS-DEKFARSL 118 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 VH A G+D M A + + T E + TF +NVF LT+ P +L Sbjct: 119 VHEAHKALG--GLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIP-LL 175 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +G + SS P+P Y+A+K A+ Y L ++ KGI+ Sbjct: 176 PKGAS-IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIR 223
>YGHA_ECO57 (P0AG85) Hypothetical oxidoreductase yghA (EC 1.-.-.-)| Length = 294 Score = 59.3 bits (142), Expect = 7e-09 Identities = 50/169 (29%), Positives = 77/169 (45%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ +A GA + +S EE + + + K +LP DLS DEK + + Sbjct: 60 GIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLS-DEKFARSL 118 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 VH A G+D M A + + T E + TF +NVF LT+ P +L Sbjct: 119 VHEAHKALG--GLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIP-LL 175 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +G + SS P+P Y+A+K A+ Y L ++ KGI+ Sbjct: 176 PKGAS-IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIR 223
>NODG_RHIS3 (P72332) Nodulation protein G| Length = 245 Score = 59.3 bits (142), Expect = 7e-09 Identities = 47/171 (27%), Positives = 82/171 (47%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIGE ++ + GA + L E+LE + + +V++ P +LS+ ++ + Sbjct: 14 ASGGIGEAIARVLHAQGAIVGLHGTRVEKLETLAAEL-----GDRVKLFPANLSNRDE-V 67 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 K + AE+ G+D +++NA + + ++ +VN+ LTR L Sbjct: 68 KALGQKAEA--DLEGVDILVNNAGITKDGL-FVRMSDADWDTVLEVNLTAVFRLTRELTH 124 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ R G + ++S G PGQ Y ASK + G+ SL E+ T+ I Sbjct: 125 PMMRRRHGRIINITSVVGVTGNPGQTNYCASKAGMIGFSKSLAQEIATRNI 175
>DHS5_CAEEL (Q10130) Putative oxidoreductase dhs-5 (EC 1.-.-.-)| Length = 378 Score = 58.9 bits (141), Expect = 9e-09 Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 1/170 (0%) Frame = +1 Query: 43 GIGEVLSMQFASLGA-KLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKE 219 GIG+ +++ A G K +L RN ++L+ VK I KH D++++ D S + S Sbjct: 99 GIGKAYTLELAKRGLRKFVLIGRNPKKLDSVKSEIEEKHSDAQIKTFVFDFGSGDFS--- 155 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM 399 S S + +++++ R + + +VN G + P M Sbjct: 156 ---SLRDYISDIDVGFVVNSVGTGRDNLERYGDNPDEDTQILRVNGMGAAEFLSCVLPPM 212 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 G G VV+SS+ G P P A Y A+K + S+ E T ++ Sbjct: 213 EKSGGGQIVVLSSSQGVRPIPMLAAYCATKALMTFLCESIDREYSTINVQ 262
>DHBY_CAEEL (O16925) Putative steroid dehydrogenase F25G6.5 (EC 1.1.1.-)| Length = 314 Score = 58.5 bits (140), Expect = 1e-08 Identities = 46/174 (26%), Positives = 81/174 (46%), Gaps = 3/174 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSS-DEKS 210 A+ GIG ++ A G + L +R K +L + K I++K+ D +V D + + Sbjct: 61 ATDGIGRSYALDLARRGFNIFLISRTKSKLVKTKKQILNKYSDIEVRYAICDFTRVSYED 120 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAA--FERPKRGALEETEEGLKATFKVNVFGTITLTRL 384 K ++HS + I +++N F+ P+ L E G+ V + LT Sbjct: 121 YKRLLHS----LNEVDIGILINNVGMCFDNPE--VLHRVEGGIDTLTNVINVNILPLTAG 174 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 + P M+ R G V + SAAG + ++YSA+K + + + L+ E +GI Sbjct: 175 ILPQMMARKSGIIVNIGSAAGSIHMAKWSVYSATKKYIEWFTSILQKEYENEGI 228
>DHBW_CAEEL (Q17704) Putative steroid dehydrogenase C06B3.5 (EC 1.1.1.-)| Length = 349 Score = 58.5 bits (140), Expect = 1e-08 Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 9/177 (5%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLS----SDEKS 210 GIG+ S + A G + + +R + +LE+ K IM K+ + +V D + SD K Sbjct: 58 GIGKSFSFELAKRGFNIYIVSRTQSKLEQTKKEIMEKYSNVEVRFATFDFTNPSISDYKK 117 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAA--FERPKRGALEETEEGLKATFKVNVFGTITLTRL 384 L S + I +++N FE P+ L +T G+ V + T+ +T L Sbjct: 118 LL-------SQLNEVSIGMLINNVGMLFEYPEN--LHKTVGGIDVVANVTILNTLPVTLL 168 Query: 385 LA---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 A P M+ R G V + S AG ++YSASK + LR E +GI Sbjct: 169 SAGILPQMVSRKTGIIVNIGSVAGAAKMAEWSVYSASKKYVEWLTGCLRKEYEHQGI 225
>YCIK_ECOLI (P31808) Hypothetical oxidoreductase yciK (EC 1.-.-.-)| Length = 252 Score = 58.2 bits (139), Expect = 2e-08 Identities = 48/170 (28%), Positives = 75/170 (44%), Gaps = 5/170 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIG +M +A GA +IL RN+E+L +V +I ++ + + +DL L Sbjct: 20 ASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHI-NEETGRQPQWFILDL------L 72 Query: 214 KEVVHSAESLFSSAGIDY-----MMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 + + L ++Y ++HNA E+ + + +VNV T LT Sbjct: 73 TCTSENCQQLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVMQVNVNATFMLT 132 Query: 379 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 + L P +L G V SS+ G+ Y+ASK A G L E Sbjct: 133 QALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYAASKFATEGMMQVLADE 182
>FABG_RICPR (P50941) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 241 Score = 57.8 bits (138), Expect = 2e-08 Identities = 45/171 (26%), Positives = 75/171 (43%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIG ++ LG+K+I+S N+E+L+ + + + + +EV + + +L Sbjct: 14 ASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYT---IEVCNLANKEECSNL 70 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + + L +AGI A+ ++ +N+ L R Sbjct: 71 ISKTSNLDILVCNAGIT----------SDTLAIRMKDQDFDKVIDINLKANFILNREAIK 120 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + +SS G PGQA Y ASK L G SL E+ T+GI Sbjct: 121 KMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGI 171
>CMTB_PSEPU (Q51977) 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase (EC| 1.3.1.58) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) Length = 259 Score = 57.4 bits (137), Expect = 3e-08 Identities = 47/170 (27%), Positives = 81/170 (47%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 + GIG + + LGA++ S ++ L + + +KH D+ + V DL S+E+ + Sbjct: 22 AHGIGLGIVERLLGLGARVTASDIDESGLSLLCERLAAKHADA-IAVHAADL-SEEQGAQ 79 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 + +A F S I + N A R LE T E LKAT N++ + +R+ P Sbjct: 80 GLHRAAVERFGSVQI---LVNCAGGGVIRPFLEHTPETLKATIDRNLWTALWCSRVFLPD 136 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 ML R G + + + + + P A Y+A+K ++G L E +G+ Sbjct: 137 MLARQYGRIINIGADSVRNGLPDHAAYNAAKGGMHGLTTGLAREFARQGV 186
>FABG_BACSU (P51831) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 246 Score = 57.0 bits (136), Expect = 3e-08 Identities = 46/172 (26%), Positives = 82/172 (47%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG +++ A GA ++++ + N+ + V I K K + D+S+ E Sbjct: 12 ASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEI--KSMGRKAIAVKADVSNPE-D 68 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 ++ ++ S+FS+ ID +++NA R + E+ +N+ G T+ + Sbjct: 69 VQNMIKETLSVFST--IDILVNNAGITRDNL-IMRMKEDEWDDVININLKGVFNCTKAVT 125 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + +SS G PGQA Y A+K + G S EL ++ I Sbjct: 126 RQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNI 177
>FABG_STAES (Q8CPI3) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 57.0 bits (136), Expect = 3e-08 Identities = 47/172 (27%), Positives = 82/172 (47%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG +++Q A G + ++ A +K++ E V I +K +S + DE Sbjct: 10 ASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVES-FAIQANVAKGDE-- 66 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 +KE++ S F S +D +++NA + + E+ N+ G + + Sbjct: 67 VKEMIKEVVSQFGS--VDVLVNNAGITKDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKVT 123 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + ++S G + PGQA Y A+K + G + EL ++GI Sbjct: 124 PQMLRQRSGAIINLTSIVGAMGNPGQANYVATKAGVIGLTKTAARELASRGI 175
>FABG_STAEQ (Q5HPW0) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 57.0 bits (136), Expect = 3e-08 Identities = 47/172 (27%), Positives = 82/172 (47%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG +++Q A G + ++ A +K++ E V I +K +S + DE Sbjct: 10 ASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVES-FAIQANVAKGDE-- 66 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 +KE++ S F S +D +++NA + + E+ N+ G + + Sbjct: 67 VKEMIKEVVSQFGS--VDVLVNNAGITKDNL-LMRMKEQEWDDVIDTNLKGVFNCIQKVT 123 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P ML + G + ++S G + PGQA Y A+K + G + EL ++GI Sbjct: 124 PQMLRQRSGAIINLTSIVGAMGNPGQANYVATKAGVIGLTKTAARELASRGI 175
>FABG_SHIFL (P0AEK3) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 57.0 bits (136), Expect = 3e-08 Identities = 41/171 (23%), Positives = 80/171 (46%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG ++ A+ GAK+I +A ++ + + + + + V +D S+ Sbjct: 13 ASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV------TDPASI 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + V+ + F +D +++NA R + +E + N+ L++ + Sbjct: 67 ESVLEKIRAEFGE--VDILVNNAGITRDNL-LMRMKDEEWNDIIETNLSSVFRLSKAVMR 123 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 124 AMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGI 174
>FABG_ECOLI (P0AEK2) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 57.0 bits (136), Expect = 3e-08 Identities = 41/171 (23%), Positives = 80/171 (46%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG ++ A+ GAK+I +A ++ + + + + + V +D S+ Sbjct: 13 ASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV------TDPASI 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + V+ + F +D +++NA R + +E + N+ L++ + Sbjct: 67 ESVLEKIRAEFGE--VDILVNNAGITRDNL-LMRMKDEEWNDIIETNLSSVFRLSKAVMR 123 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 124 AMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGI 174
>AYR1_YEAST (P40471) NADPH-dependent 1-acyldihydroxyacetone phosphate reductase| (EC 1.1.1.101) (Acylglycerone-phosphate reductase) (1-acyl DHAP reductase) (Acyl/alkyl DHAP reductase) (ADR) Length = 297 Score = 57.0 bits (136), Expect = 3e-08 Identities = 49/168 (29%), Positives = 84/168 (50%), Gaps = 2/168 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIG ++ + A G + AR E + + + + + ++ +D+S E Sbjct: 17 ASGGIGYEVTKELARNGYLVYACARRLEPMAQ----LAIQFGNDSIKPYKLDISKPE--- 69 Query: 214 KEVVHSAESLFSSA--GIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 E+V + L ++ G +++N A + AL+ T+ ++ FKVNVFG I + R L Sbjct: 70 -EIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALDATDAAVEQCFKVNVFGHINMCREL 128 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 + F++ + G V S AG V P ++YSASK A++ Y L E+ Sbjct: 129 SEFLI-KAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEM 175
>Y484_MYCTU (Q11150) Putative oxidoreductase Rv0484c/MT0502 (EC 1.-.-.-)| Length = 251 Score = 56.6 bits (135), Expect = 5e-08 Identities = 47/178 (26%), Positives = 76/178 (42%), Gaps = 6/178 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNI------MSKHPDSKVEVLPMDLS 195 AS GIGE + A+ G ++ AR + + + + I D+ VE L LS Sbjct: 16 ASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALS 75 Query: 196 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 +D +++NA + + + E + + NV GT+ + Sbjct: 76 R--------------------VDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRV 115 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 TR L P ++D G G V ++S A G A Y+A+KHA +LR EL K ++ Sbjct: 116 TRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVR 173
>Y325_THEMA (Q9WYG0) Hypothetical oxidoreductase TM0325 (EC 1.-.-.-)| Length = 251 Score = 56.6 bits (135), Expect = 5e-08 Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 2/174 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSD-EKS 210 A GIG+ ++ FA GAK+ ++ ++E+ + I S + + D++ D E+ Sbjct: 13 AGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSM--GGEAAFIFGDVAKDAEQI 70 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEET-EEGLKATFKVNVFGTITLTRLL 387 +K+ V + L D +++NA G +EET EE T VNV G L++ Sbjct: 71 VKKTVETFGRL------DILVNNAGIV--PYGNIEETSEEDFDKTMAVNVKGPFLLSKYA 122 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M +G G V +SS AG + P + +YS SK AL G SL + GI+ Sbjct: 123 VEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIR 176
>DHB2_MOUSE (P51658) Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62)| (17-beta-HSD 2) (17-beta-hydroxysteroid dehydrogenase 2) Length = 381 Score = 56.2 bits (134), Expect = 6e-08 Identities = 49/173 (28%), Positives = 77/173 (44%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A G G L+ LG + +KE + + KH ++ VL MD++ E+ + Sbjct: 91 ADSGFGHGLAKHLDKLGFTVFAGVLDKEGPGAEE---LRKHCSERLSVLQMDVTKPEQ-I 146 Query: 214 KEVVHSAESLFSSAGIDYMMHNAA-FERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 K+ G+ +++NA F P G L K VN FGT+ +T+ Sbjct: 147 KDAHSKVTEKIQDKGLWAVVNNAGVFHLPIDGELIPMSIYRKC-MAVNFFGTVEVTKAFL 205 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P +L + G V +SS G VP + Y+A+K AL + +R EL G+K Sbjct: 206 P-LLRKSKGRLVNVSSMGGTVPLQMTSAYAATKAALTMFSTIIRQELDKWGVK 257
>TRN2_DATST (P50163) Tropinone reductase 2 (EC 1.1.1.236) (Tropinone| reductase-II) (TR-II) Length = 260 Score = 56.2 bits (134), Expect = 6e-08 Identities = 50/171 (29%), Positives = 82/171 (47%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 SRGIG + + ASLGA + +RN++EL SK KVE DLSS + + Sbjct: 18 SRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSK--GFKVEASVCDLSSRSER-Q 74 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 E++++ + F ++ +++NA K A + T E +N L+ L PF Sbjct: 75 ELMNTVANHFHGK-LNILVNNAGIVIYKE-AKDYTVEDYSLIMSINFEAAYHLSVLAHPF 132 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G+ V +SS +G + P +A+Y A+K A++ L E I+ Sbjct: 133 LKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIR 183
>DHBV_CAEEL (Q17703) Putative steroid dehydrogenase C06B3.4 (EC 1.1.1.-)| Length = 314 Score = 55.8 bits (133), Expect = 8e-08 Identities = 47/176 (26%), Positives = 79/176 (44%), Gaps = 5/176 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ S + A G + + +R + +LE K I+ HPD +V D ++ S Sbjct: 55 ATDGIGKSYSFELAKRGFNVYIVSRTQSKLEHTKKEILEVHPDIEVRFATFDFTNPSVSD 114 Query: 214 KEVVHSAESLFSSAGIDYMMHNAA--FERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 E + S + I +++N F+ P+ L + G+ + V + T+ T L Sbjct: 115 YEKLLSK---LNEVSIGILINNVGMFFDYPE--MLHKINGGIDSIANVTIINTLPATLLS 169 Query: 388 A---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 A P M+ R G V + S AG ++YSA+K + L+ E +GI Sbjct: 170 AGILPQMVPRKAGIIVNIGSVAGLATMAEWSVYSATKKYVEWITGCLQKEYGHQGI 225
>GNO_GLUOX (P50199) Gluconate 5-dehydrogenase (EC 1.1.1.69)| (5-keto-D-gluconate 5-reductase) Length = 256 Score = 55.8 bits (133), Expect = 8e-08 Identities = 45/173 (26%), Positives = 83/173 (47%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG L+ A GA+++L+ RN E L+ + ++ + V + +D+ ++ Sbjct: 19 ASRGIGLTLAKGLARYGAEVVLNGRNAESLDSAQSGFEAEGLKASTAVFDV---TDQDAV 75 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTITLTRLLA 390 + V + E ID +++NA +R R LEE + + NV + + +A Sbjct: 76 IDGVAAIER--DMGPIDILINNAGIQR--RAPLEEFSRKDWDDLMSTNVNAVFFVGQAVA 131 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M+ RG G V + S ++ PG A Y+A+K A+ + ++ G++ Sbjct: 132 RHMIPRGRGKIVNICSVQSELARPGIAPYTATKGAVKNLTKGMATDWGRHGLQ 184
>DHBX_CAEEL (O17795) Putative steroid dehydrogenase F11A5.12 (EC 1.1.1.-)| Length = 315 Score = 55.8 bits (133), Expect = 8e-08 Identities = 47/176 (26%), Positives = 81/176 (46%), Gaps = 5/176 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ S + A G + + +R + +LE+ K +I+ K PD +V D ++ + Sbjct: 55 ATDGIGKSYSFELARRGFNVYIVSRTQSKLEQTKKDILEKQPDIEVRFATYDFTNPSVTD 114 Query: 214 KEVVHSAESLFSSAGIDYMMHNAA--FERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 E + S + + +++N F+ P+ L + G+ + V + T+ T L Sbjct: 115 YEKLLSK---LNEVSVGILINNVGMFFDYPE--MLHKINGGIDSIANVIIINTLPATLLS 169 Query: 388 A---PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 A P M+ R G V + S AG V ++YSA+K + LR E GI Sbjct: 170 AGILPQMVSRKAGIIVNIGSFAGVVKLAEWSIYSATKKYVEWLTGCLRKEYSHHGI 225
>WWOX_HUMAN (Q9NZC7) WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile| site FRA16D oxidoreductase) Length = 414 Score = 55.5 bits (132), Expect = 1e-07 Identities = 52/176 (29%), Positives = 82/176 (46%), Gaps = 9/176 (5%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG + FA GA +IL+ RN I+ + +KVE + +DL+ L Sbjct: 132 ANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAMTLDLA----LL 187 Query: 214 KEVVHSAESL-FSSAGIDYMMHNAA-FERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 + V H AE+ + + ++ NAA F P T++GL+ TF+VN G L +LL Sbjct: 188 RSVQHFAEAFKAKNVPLHVLVCNAATFALP----WSLTKDGLETTFQVNHLGHFYLVQLL 243 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQAL----YSASKHALNGYFASL---RSELC 534 + +V+SS + + +L +S N Y+A L RS+LC Sbjct: 244 QDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLC 299
>NODG_RHIME (P06234) Nodulation protein G (Host-specificity of nodulation| protein C) Length = 245 Score = 55.5 bits (132), Expect = 1e-07 Identities = 45/171 (26%), Positives = 81/171 (47%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS IG ++ + GA + L E+LE + + +V++ P +L++ ++ + Sbjct: 14 ASGAIGGAIARVLHAQGAIVGLHGTQIEKLETLATEL-----GDRVKLFPANLANRDE-V 67 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 K + AE+ G+D +++NA + L + +VN+ LTR + Sbjct: 68 KALGQRAEA--DLEGVDILVNNAGITKDGL-FLHMADPDWDIVLEVNLTAMFRLTREITQ 124 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ R G + ++S AG + PGQ Y ASK + G+ SL E+ T+ I Sbjct: 125 QMIRRRNGRIINVTSVAGAIGNPGQTNYCASKAGMIGFSKSLAQEIATRNI 175
>FABG_SALTY (P0A2C9) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/171 (22%), Positives = 80/171 (46%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG ++ + GAK+I +A ++ + + + + + V +D S+ Sbjct: 13 ASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYLGANGKGLMLNV------TDPASI 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + V+ + + F +D +++NA R + ++ + N+ L++ + Sbjct: 67 ESVLENIRAEFGE--VDILVNNAGITRDNL-LMRMKDDEWNDIIETNLSSVFRLSKAVMR 123 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 124 AMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGI 174
>FABG_SALTI (P0A2D0) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/171 (22%), Positives = 80/171 (46%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG ++ + GAK+I +A ++ + + + + + V +D S+ Sbjct: 13 ASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYLGANGKGLMLNV------TDPASI 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + V+ + + F +D +++NA R + ++ + N+ L++ + Sbjct: 67 ESVLENIRAEFGE--VDILVNNAGITRDNL-LMRMKDDEWNDIIETNLSSVFRLSKAVMR 123 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + + S G + GQA Y+A+K L G+ SL E+ ++GI Sbjct: 124 AMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGI 174
>FABG_CUPLA (P28643) 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast| precursor (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) Length = 320 Score = 55.1 bits (131), Expect = 1e-07 Identities = 43/173 (24%), Positives = 86/173 (49%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ +++ G K++++ AR+ +E E V I + + D+S +E Sbjct: 85 ASRGIGKAIALSLGKAGCKVLVNYARSSKEAEEVSKEIEAF--GGQALTFGGDVSKEE-D 141 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL-KATFKVNVFGTITLTRLL 387 ++ ++ +A + + +D +++NA R G L ++ + +N+ G T+ Sbjct: 142 VEAMIKTAVDAWGT--VDILVNNAGITRD--GLLMRMKKSQWQEVIDLNLTGVFLCTQAA 197 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 A M+ + G + ++S G V GQA YSA+K + G+ ++ E ++ I Sbjct: 198 AKIMMKKKKGRIINIASVVGLVGNAGQANYSAAKAGVIGFTKTVAREYASRNI 250
>WWOX_PONPY (Q5R9W5) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 414 Score = 55.1 bits (131), Expect = 1e-07 Identities = 52/176 (29%), Positives = 82/176 (46%), Gaps = 9/176 (5%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG + FA GA +IL+ RN I+ + +KVE + +DL+ L Sbjct: 132 ANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAVTLDLA----LL 187 Query: 214 KEVVHSAESL-FSSAGIDYMMHNAA-FERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 + V H AE+ + + ++ NAA F P T++GL+ TF+VN G L +LL Sbjct: 188 RSVQHFAEAFKAKNVPLHVLVCNAATFALP----WSLTKDGLETTFQVNHLGHFYLVQLL 243 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQAL----YSASKHALNGYFASL---RSELC 534 + +V+SS + + +L +S N Y+A L RS+LC Sbjct: 244 QDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLC 299
>ACT3_STRCO (P16544) Putative ketoacyl reductase (EC 1.3.1.-)| Length = 261 Score = 54.7 bits (130), Expect = 2e-07 Identities = 49/175 (28%), Positives = 81/175 (46%), Gaps = 4/175 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG ++ + G ++ + AR +E L + ++ + D +S+ Sbjct: 14 ATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGR------TCDVRSV 67 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKA-TFKVNVFGTITLTR-- 381 E+ ++ G +D +++NA RP GA E + L + N+ G +T+ Sbjct: 68 PEIEALVAAVVERYGPVDVLVNNAG--RPGGGATAELADELWLDVVETNLTGVFRVTKQV 125 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 L A ML+RG G V ++S GK A YSASKH + G+ +L EL GI Sbjct: 126 LKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKALGLELARTGI 180
>FABG_VIBCH (Q9KQH7) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/171 (22%), Positives = 81/171 (47%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG+ ++ A GAK+I +A ++ + + + + V ++ +S+ Sbjct: 13 ASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNV------TNPESI 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + V+ + F G+D +++NA R + EE + N+ L++ + Sbjct: 67 EAVLKAITDEFG--GVDILVNNAGITRDNL-LMRMKEEEWSDIMETNLTSIFRLSKAVLR 123 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + + S G + GQA Y+A+K + G+ S+ E+ ++G+ Sbjct: 124 GMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGV 174
>FABG_HAEIN (P43713) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 242 Score = 54.3 bits (129), Expect = 2e-07 Identities = 40/171 (23%), Positives = 81/171 (47%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ++RGIG ++ + +S GA +I +A +++ E + + K + V +D++S+ Sbjct: 11 STRGIGRAIAEELSSKGAFVIGTATSEKGAEAISAYLGDKGKGLVLNV------TDKESI 64 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + ++ ++ F ID +++NA R + EE + N+ L++ + Sbjct: 65 ETLLEQIKNDFGD--IDILVNNAGITRDNLLMRMKDEEWFDI-MQTNLTSVYHLSKAMLR 121 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + + S G PGQ Y A+K + G+ SL E+ +GI Sbjct: 122 SMMKKRFGRIINIGSVVGSTGNPGQTNYCAAKAGVVGFSKSLAKEVAARGI 172
>CBR2_CAEEL (Q21929) Probable carbonyl reductase [NADPH] (EC 1.1.1.184)| (NADPH-dependent carbonyl reductase) Length = 251 Score = 54.3 bits (129), Expect = 2e-07 Identities = 48/175 (27%), Positives = 87/175 (49%), Gaps = 6/175 (3%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM--DLSSDEKSLK 216 GIG+ + + A GA++I ARN+ L +++ + + ++P+ D+S++E+ L Sbjct: 20 GIGKEICLSLAKAGAQVIAFARNEANLL----SLVKETTSLRYTIIPIVGDVSANEEVLF 75 Query: 217 EVV---HSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +++ L ++AGI + T++ + TF VNV G I + +L+ Sbjct: 76 KLIVPHFPIHGLVNNAGI----------ATNHAIGQITQQSIDRTFAVNVRGPILIAQLV 125 Query: 388 APFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 A +DR + G V +SS A P +Y ASK AL+ L +EL ++ I+ Sbjct: 126 ARNFVDRQIKGSIVNISSQAAIRPLDNHTVYCASKAALDMVTRCLANELGSQNIR 180
>SDR1_PICAB (Q08632) Short-chain type dehydrogenase/reductase (EC 1.-.-.-)| Length = 271 Score = 54.3 bits (129), Expect = 2e-07 Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 3/169 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG +++ A GAK+++ + N+ E V I +K P S V + +D Sbjct: 29 ASRGIGREIALNMAEKGAKVVIHYSSNQHAAEEVASIINNKSPSSGDGVRAIVCKADVAE 88 Query: 211 LKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEET-EEGLKATFKVNVFGTITLTRL 384 +V ++ + G + +++NA K L +T +E F+VN G +R Sbjct: 89 PSQVAQLFDTAEHAFGPLHIVVNNAGVTDSKYPTLAQTSDEEWDRIFQVNCKGAFLCSRE 148 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 A ++ G G + +SS+ +P P Y+ASK A+ L EL Sbjct: 149 AAKRVVRGGGGRIINISSSLVAMPIPRYGAYTASKAAVEMMTRILAQEL 197
>YXBG_BACSU (P46331) Hypothetical oxidoreductase yxbG (EC 1.-.-.-)| Length = 273 Score = 54.3 bits (129), Expect = 2e-07 Identities = 44/173 (25%), Positives = 84/173 (48%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ + FA+ GA++I+ NK+++E I + + E +D+ SDE S+ Sbjct: 14 AATGIGQATAEVFANEGARVIIGDINKDQMEETVDAI--RKNGGQAESFHLDV-SDENSV 70 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 K A+ + + G ID + +NA ++ E + V++ GT ++ L Sbjct: 71 KAF---ADQIKDACGTIDILFNNAGVDQEGGKVHEYPVDLFDRIIAVDLRGTFLCSKYLI 127 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P ML+ G G + SS +G+ ++ Y+A+K + ++ + GI+ Sbjct: 128 PLMLENG-GSIINTSSMSGRAADLDRSGYNAAKGGITNLTKAMAIDYARNGIR 179
>YHXD_BACSU (P40398) Hypothetical oxidoreductase yhxD (EC 1.-.-.-) (ORFY)| Length = 299 Score = 53.9 bits (128), Expect = 3e-07 Identities = 41/169 (24%), Positives = 82/169 (48%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG ++ +A GA + ++ +E+ + + + + K ++P DLS DE +++ Sbjct: 62 GIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLIPGDLS-DESFCQDL 120 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 V +S G+D + A ++ + E + TF+VNVF + + P++ Sbjct: 121 VK--QSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVFSLYWVVKAALPYLP 178 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + + +S G P+P Y+A+K+A+ G+ L +L +KGI+ Sbjct: 179 EGAS--IITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIR 225
>TRNH_DATST (P50165) Tropinone reductase homolog (EC 1.1.1.-) (P29X)| Length = 268 Score = 53.9 bits (128), Expect = 3e-07 Identities = 45/171 (26%), Positives = 75/171 (43%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 +RGIG + + A+ GA++ +R++ +L+ K V + S ++L Sbjct: 26 TRGIGYAIVEELANFGAEVYTCSRSQNDLDECLEKWRRKGFKVSGPVCDVSSISQRQTLM 85 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 E V S+ + ++ +++NA PK A T E N + L +L P Sbjct: 86 ESVTSS----FNGKLNILINNAGTTIPKE-ATNFTAEDYSIIMGTNFEASYNLCQLAHPL 140 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G V SSAAG + P ++Y+ASK A+N SL E I+ Sbjct: 141 LKASGNASIVFNSSAAGVIAVPLSSIYAASKGAINQVTKSLACEWAKDSIR 191
>PHBB_CHRVI (P45375) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 246 Score = 53.1 bits (126), Expect = 5e-07 Identities = 44/168 (26%), Positives = 74/168 (44%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG + + A G ++ + E + + V D+SS + S + V Sbjct: 13 GIGTSICTRLAKDGCTVVANCHPSEAAAAEEWKQARAAEGFDIAVFTADVSSFDDSARMV 72 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 E + ID +++ A R K E + +A VN+ +TR + ML Sbjct: 73 REITEQV---GPIDILVNCAGITRDKTFKKME-QAHWEAVINVNLNSVFNVTRQVWDGML 128 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 +RG G + +SS G+ GQA YSA+K ++G+ +L E +KG+ Sbjct: 129 ERGFGRIINISSVNGQRGQFGQANYSAAKAGMHGFTMALAQEGASKGV 176
>NODG_AZOBR (P17611) Nodulation protein G| Length = 246 Score = 53.1 bits (126), Expect = 5e-07 Identities = 36/117 (30%), Positives = 59/117 (50%) Frame = +1 Query: 196 SDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 SD +S K +V E+ +D +++NA R K A + + A N+ + Sbjct: 63 SDFESCKAMVAKIEA--DLGPVDILVNNAGITRDKFFAKMDKAQW-DAVIATNLSSLFNV 119 Query: 376 TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 T+ ++P M +RG G + +SS G GQ YSA+K + G+ +L +EL TKG+ Sbjct: 120 TQQVSPKMAERGWGRIINISSVNGVKGQAGQTNYSAAKAGVIGFTKALAAELATKGV 176
>DHRS2_HUMAN (Q13268) Dehydrogenase/reductase SDR family member 2 (EC 1.1.-.-)| (HEP27 protein) (Protein D) Length = 257 Score = 52.8 bits (125), Expect = 7e-07 Identities = 43/172 (25%), Positives = 79/172 (45%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ++ GIG ++ + A GA +++S+R ++ ++R + + V + + D + L Sbjct: 21 STSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQL 80 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 A++L G+D+++ +A L +E+ VNV L L P Sbjct: 81 V-----AKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP 135 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +M +R G +++SS A P +Y+ SK AL G +L EL K I+ Sbjct: 136 YMENR-RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 186
>WWOX_CHICK (Q5F389) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 414 Score = 52.8 bits (125), Expect = 7e-07 Identities = 52/175 (29%), Positives = 85/175 (48%), Gaps = 8/175 (4%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG + FA GA +IL+ RN I+ + +KVE + +DL+ SL Sbjct: 132 ANSGIGFETAKSFALHGAYVILACRNMSRGNDAVQRILEEWHKAKVEAMTLDLA----SL 187 Query: 214 KEVVHSAESLFS-SAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + V + AE+ S + + ++ NAA + TE+GL++TF+VN G L +LL Sbjct: 188 RSVQNFAEAFKSKNMPLHILVCNAAI---FGSSWCLTEDGLESTFQVNHLGHFYLVQLLE 244 Query: 391 PFMLDRGMGHFVVMSSAAGKV----PTPGQALYSASKHALNGYFASL---RSELC 534 + VV+SS + + + G+ +S + Y+A L RS+LC Sbjct: 245 DILRRSSPARVVVVSSESHRFTEIKDSSGKLDFSLLSPSKKEYWAMLAYNRSKLC 299
>UCPA_ECOLI (P37440) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 52.8 bits (125), Expect = 7e-07 Identities = 48/173 (27%), Positives = 80/173 (46%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A +GIGE ++ FA GA LIL + E +E++ + + V + D S+ Sbjct: 14 ALQGIGEGIARTFARHGANLILLDISPE-IEKLADELCGRGHRCTAVVADV---RDPASV 69 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + A+ ID +++NA R L+ +++ +N+ G +T+ + P Sbjct: 70 AAAIKRAKE--KEGRIDILVNNAGVCR-LGSFLDMSDDDRDFHIDINIKGVWNVTKAVLP 126 Query: 394 FMLDRGMGHFVVMSSAAG-KVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M+ R G V+MSS G V PG+ Y+ +K A+ G SL E GI+ Sbjct: 127 EMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQSGIR 179
>UCPA_ECO57 (Q8XBJ4) Oxidoreductase ucpA (EC 1.-.-.-)| Length = 263 Score = 52.8 bits (125), Expect = 7e-07 Identities = 48/173 (27%), Positives = 80/173 (46%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A +GIGE ++ FA GA LIL + E +E++ + + V + D S+ Sbjct: 14 ALQGIGEGIARTFARHGANLILLDISPE-IEKLADELCGRGHRCTAVVADV---RDPASV 69 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + A+ ID +++NA R L+ +++ +N+ G +T+ + P Sbjct: 70 AAAIKRAKE--KEGRIDILVNNAGVCR-LGSFLDMSDDDRDFHIDINIKGVWNVTKAVLP 126 Query: 394 FMLDRGMGHFVVMSSAAG-KVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M+ R G V+MSS G V PG+ Y+ +K A+ G SL E GI+ Sbjct: 127 EMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQSGIR 179
>GS39_BACSU (P80873) General stress protein 39 (GSP39) (EC 1.-.-.-)| Length = 285 Score = 52.4 bits (124), Expect = 9e-07 Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 1/170 (0%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNK-EELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKE 219 GIG +S+ +A GA + + +++ E+ E K + + K ++ D+ +E + Sbjct: 52 GIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRV--EQEGVKCLLIAGDVGEEEFCNEA 109 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM 399 V + + L G+D +++NA + PK + T E L TFK N + LT+ ++ Sbjct: 110 VEKTVKEL---GGLDILVNNAGEQHPKESIKDITSEQLHRTFKTNFYSQFYLTKKAIDYL 166 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + + +S V P Y+A+K A+N + ++ L GI+ Sbjct: 167 --KPGSAIINTTSINPYVGNPTLIDYTATKGAINAFTRTMAQALVKDGIR 214
>SDH_AGRTU (Q9KWN1) Serine 3-dehydrogenase (EC 1.1.1.276)| Length = 249 Score = 52.4 bits (124), Expect = 9e-07 Identities = 42/172 (24%), Positives = 77/172 (44%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G G+ + +F G K+I + R E LE + + S ++ +DE++ Sbjct: 10 ATSGFGQATAQRFVKEGWKVIGTGRRAERLEALSAELGSAFHGVAFDI------TDEEAT 63 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 K+ + F ID +++NA A + + + N+ G + +T L P Sbjct: 64 KKALAGLPDGFRD--IDILVNNAGLALGTAPAPQVPLKDWQTMVDTNITGLLNVTHHLLP 121 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +++R G + +SS A P G +Y +K L + LRS+L KG++ Sbjct: 122 TLIER-KGIVINLSSVAAHYPYLGGNVYGGTKAFLRQFSLGLRSDLHGKGVR 172
>DHRS6_HUMAN (Q9BUT1) Dehydrogenase/reductase SDR family member 6 precursor (EC| 1.1.-.-) (Oxidoreductase UCPA) Length = 245 Score = 52.4 bits (124), Expect = 9e-07 Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A++GIG+ ++ FA GAK+I + N+ +L+ + K+P + VL + Sbjct: 14 AAQGIGQAAALAFAREGAKVIATDINESKLQE-----LEKYPGIQTRVLDVTKKKQIDQF 68 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 V + LF+ AG ++ H L+ E+ + +NV + + P Sbjct: 69 ASEVERLDVLFNVAG--FVHHGT--------VLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 Query: 394 FMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGYFASLRSELCTKGIK 549 ML + G+ + MSS A V + +YS +K A+ G S+ ++ +GI+ Sbjct: 119 KMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171
>TRN2_HYONI (P50164) Tropinone reductase 2 (EC 1.1.1.236) (Tropinone| reductase-II) (TR-II) Length = 260 Score = 52.4 bits (124), Expect = 9e-07 Identities = 49/171 (28%), Positives = 77/171 (45%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 SRGIG + + A+LGA + +RN++EL+ SK VE DLSS +S + Sbjct: 18 SRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSK--GFNVEASVCDLSS--RSER 73 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 E S ++ +++NA K A + T E +N L+ L PF Sbjct: 74 EEFMKTVSNHFHGKLNILVNNAGIVIYKE-AKDYTMEDYSHIMSINFEAAYHLSVLAHPF 132 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G+ V +SS +G P +A+Y A+K A++ L E I+ Sbjct: 133 LKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWAKDNIR 183
>WWOX_BRARE (Q803A8) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 412 Score = 52.0 bits (123), Expect = 1e-06 Identities = 46/138 (33%), Positives = 71/138 (51%), Gaps = 3/138 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG + FA GA +IL+ RN+ + IM + ++VEVLP+DL+ SL Sbjct: 129 ANSGIGFETARSFALHGAHVILACRNQSRASKAASLIMGEWSKARVEVLPLDLA----SL 184 Query: 214 KEVVHSAESLFSSA--GIDYMMHNAAF-ERPKRGALEETEEGLKATFKVNVFGTITLTRL 384 + V AE LF + + ++ NAA +P R TE+G ++TF++ G L +L Sbjct: 185 RSVRQFAE-LFKATKLPLHVLVCNAAVCSQPWR----LTEDGFESTFQICHLGHFLLVQL 239 Query: 385 LAPFMLDRGMGHFVVMSS 438 L + VV+SS Sbjct: 240 LQDVLRLSAPARVVVVSS 257
>VDLC_HELPJ (Q9ZKW1) Probable short-chain type dehydrogenase/reductase vdlC (EC| 1.-.-.-) Length = 271 Score = 52.0 bits (123), Expect = 1e-06 Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 1/167 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIG + + G K+ +R+ + H + E + +D+S D +L Sbjct: 7 ASSGIGLECVLMLLNQGYKVYALSRHATLCVALNHALC--------ECVDIDVS-DSNAL 57 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLLA 390 KEV + + D ++++A + G++E+T E +K F VN F + +L Sbjct: 58 KEVFLNISA--KEDHCDVLINSAGYG--VFGSVEDTPIEEVKKQFSVNFFALCEVVQLCL 113 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P + ++ +SS AG+V YSASKHAL Y +LR EL Sbjct: 114 PLLKNKPYSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLEL 160
>BPHB_BURCE (P47227) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 277 Score = 51.6 bits (122), Expect = 1e-06 Identities = 46/168 (27%), Positives = 78/168 (46%), Gaps = 5/168 (2%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G L +F + GAK+ + ++ E L ++ + H D+ + ++ D +SL++ Sbjct: 16 GLGRALVDRFVAEGAKVAVLDKSAERLAELE----TDHGDNVLGIV-----GDVRSLEDQ 66 Query: 223 VHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFK----VNVFGTITLTRLL 387 +A + G ID ++ NA ++ EE L A F +NV G I + Sbjct: 67 KQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIHAVKAC 126 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P ++ G+ + S AG P G LY+A+KHA+ G L EL Sbjct: 127 LPALV-ASRGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFEL 173
>BUTA_STAES (Q8CQD2) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 257 Score = 51.6 bits (122), Expect = 1e-06 Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G+G+ ++ + A+ G ++L N+ L + K + D+S +K Sbjct: 10 AAGGLGKGIAERLANDGFNIVLQDINEALLLETEKEFKEK--GYQAVAYKSDVSK-KKEQ 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA- 390 +E+V A + F +D M++NA + LE EE L F +NVFGT+ + A Sbjct: 67 EELVQFAVTEFGQ--LDVMVNNAGVDAVTP-ILEIGEEELSKLFNINVFGTLFGIQAAAN 123 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 F+ + G + S AG YSA+KH++ + + EL KGI Sbjct: 124 QFIKQKSKGKIINACSIAGHESYEVLGTYSATKHSVRSFTQTAAKELADKGI 175
>SPRE_HUMAN (P35270) Sepiapterin reductase (EC 1.1.1.153) (SPR)| Length = 261 Score = 51.2 bits (121), Expect = 2e-06 Identities = 54/181 (29%), Positives = 86/181 (47%), Gaps = 16/181 (8%) Frame = +1 Query: 34 ASRGIGEVLSMQFASL---GAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 204 ASRG G L+ ASL G+ L+LSARN E L +++ + ++ +V +P DL + E Sbjct: 15 ASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGA-E 73 Query: 205 KSLKEVVHSAESLFSSAGID--YMMHNAAFERPKRGALEETEEG---LKATFKVNVFGTI 369 L++++ + L G+ +++NA G+L + +G L + +VN + + Sbjct: 74 AGLQQLLGALRELPRPKGLQRLLLINNA-------GSLGDVSKGFVDLSDSTQVNNYWAL 126 Query: 370 TLTRLLA-------PFMLDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGYFASLRS 525 LT +L F G+ VV +SS P G ALY A K A + F L Sbjct: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 Query: 526 E 528 E Sbjct: 187 E 187
>WWOX_MOUSE (Q91WL8) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 414 Score = 51.2 bits (121), Expect = 2e-06 Identities = 49/175 (28%), Positives = 80/175 (45%), Gaps = 8/175 (4%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG + FA GA +IL+ RN I+ + +KVE + +DL+ L Sbjct: 132 ANSGIGFETAKSFALHGAHVILACRNLSRASEAVSRILEEWHKAKVEAMTLDLA----VL 187 Query: 214 KEVVHSAESL-FSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + V H AE+ + + ++ NA G T++GL+ TF+VN G L +LL Sbjct: 188 RSVQHFAEAFKAKNVSLHVLVCNAGTFALPWGL---TKDGLETTFQVNHLGHFYLVQLLQ 244 Query: 391 PFMLDRGMGHFVVMSSAAGKV----PTPGQALYSASKHALNGYFASL---RSELC 534 + +V+SS + + + G+ S + Y+A L RS+LC Sbjct: 245 DVLCRSSPARVIVVSSESHRFTDINDSSGKLDLSRLSPPRSDYWAMLAYNRSKLC 299
>PHAB_ACISR (P50203) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 248 Score = 51.2 bits (121), Expect = 2e-06 Identities = 46/166 (27%), Positives = 80/166 (48%), Gaps = 4/166 (2%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSK-HPDSKVEVLPMDLSSDEKSLKE 219 GIG + Q + G K+I + +EE +R K + S+ DS V + DL++ E + Sbjct: 15 GIGSEICRQLVTAGYKIIATVVPREE-DREKQWLQSEGFQDSDVRFVLTDLNNHEAATAA 73 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERP---KRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + E++ + +D +++NA R K+ + E+ + + K T+T+ + Sbjct: 74 I---QEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKT----LFTVTQPVF 126 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 ML++ G V +SS G GQA YSASK + G+ +L E Sbjct: 127 NKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALAQE 172
>HCD2_DROME (O18404) 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35)| (3-hydroxyacyl-CoA dehydrogenase type II) (Type II HADH) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (Scully protein) Length = 255 Score = 51.2 bits (121), Expect = 2e-06 Identities = 51/182 (28%), Positives = 80/182 (43%), Gaps = 13/182 (7%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G + + A GA +IL+ +L K N ++K KV +P+D++S EK + Sbjct: 15 GLGRATAERLAKQGASVILA-----DLPSSKGNEVAKELGDKVVFVPVDVTS-EKDVSAA 68 Query: 223 VHSAESLF-------SSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 + +A+ F + AG + F + LE+ + +N GT + R Sbjct: 69 LQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQR----VININTVGTFNVIR 124 Query: 382 LLAPFM------LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 L A M D G V +S A GQA YSASK A+ G + +L T+G Sbjct: 125 LSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQG 184 Query: 544 IK 549 I+ Sbjct: 185 IR 186
>TRN1_DATST (P50162) Tropinone reductase 1 (EC 1.1.1.206) (Tropinone| reductase-I) (TR-I) (Tropine dehydrogenase) Length = 273 Score = 51.2 bits (121), Expect = 2e-06 Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 3/174 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSD---EK 207 S+GIG + + A LGA++ +RN++EL+ + + VE DL S +K Sbjct: 30 SKGIGYAIVEELAGLGARVYTCSRNEKELDECLE--IWREKGLNVEGSVCDLLSRTERDK 87 Query: 208 SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 ++ V H + ++ +++NA K A + TE+ N L+++ Sbjct: 88 LMQTVAHVFDGK-----LNILVNNAGVVIHKE-AKDFTEKDYNIIMGTNFEAAYHLSQIA 141 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P + G+ + +SS AG P +LYSASK A+N SL E I+ Sbjct: 142 YPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIR 195
>DHB1_MOUSE (P51656) Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62)| (17-beta-HSD 1) (17-beta-hydroxysteroid dehydrogenase 1) Length = 344 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/122 (33%), Positives = 59/122 (48%), Gaps = 1/122 (0%) Frame = +1 Query: 157 PDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGL 333 P +E+L +D+ D KS V +A++ + +D ++ NA R G LE E + Sbjct: 56 PPGSLEILELDVR-DSKS----VAAAQACVTEGRVDVLVCNAG--RGLFGPLEAHELNAV 108 Query: 334 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 513 A VNV GTI + + P M R G +V +S G + P +Y ASK AL G Sbjct: 109 GAVLDVNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCE 168 Query: 514 SL 519 SL Sbjct: 169 SL 170
>LVR_LEIAQ (Q9LBG2) Levodione reductase (EC 1.1.1.-)| ((6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase) Length = 267 Score = 51.2 bits (121), Expect = 2e-06 Identities = 44/169 (26%), Positives = 72/169 (42%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G +++ A+ GAKL L + E LE K ++ PD++V D+ SDE ++ Sbjct: 24 GLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADV-SDEAQVEAY 82 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 V + F ID +NA E + T +N+ G + M Sbjct: 83 VTATTERFGR--IDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFLGLEKVLKIMR 140 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 ++G G V +S G Q+ Y+A+KH + G + E GI+ Sbjct: 141 EQGSGMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNSAVEYGRYGIR 189
>VDLC_HELPY (O05730) Probable short-chain type dehydrogenase/reductase vdlC (EC| 1.-.-.-) Length = 284 Score = 51.2 bits (121), Expect = 2e-06 Identities = 47/167 (28%), Positives = 77/167 (46%), Gaps = 1/167 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS GIG ++ G K+ +R+ + H + E + +D+S D +L Sbjct: 18 ASSGIGLECALMLLDQGYKVYALSRHATLCVALNHALC--------ESVDIDVS-DSNAL 68 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLLA 390 KEV + + D ++++A + G++E+T E +K F VN F + + Sbjct: 69 KEVFSNISA--KEKYCDVLINSAGYG--VFGSVEDTPIEEVKKQFSVNFFALCEVVQFCL 124 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P + ++ +SS AG+V YSASKHAL Y +LR EL Sbjct: 125 PLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLEL 171
>PGDH_MACFA (Q8MJY8) 15-hydroxyprostaglandin dehydrogenase [NAD+] (EC| 1.1.1.141) (PGDH) (Prostaglandin dehydrogenase 1) Length = 266 Score = 50.8 bits (120), Expect = 2e-06 Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 5/177 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A++GIG + GAK+ L N E + K + K K + D++ D++ L Sbjct: 13 AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEKFEPQKTLFIQCDVA-DQQQL 71 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ F +D +++NA E+ + T ++N+ I+ T L Sbjct: 72 RDTFRKVVDHFGR--LDILVNNAGVNN---------EKNWEKTLQINLVSVISGTYLGLD 120 Query: 394 FMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKHALNGY--FASLRSELCTKGIK 549 +M + G + MSS AG +P Q +Y ASKH + G+ A+L + L G++ Sbjct: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
>BUTA_STAEQ (Q5HKG6) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 257 Score = 50.8 bits (120), Expect = 2e-06 Identities = 46/169 (27%), Positives = 77/169 (45%), Gaps = 1/169 (0%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G+ ++ + A+ G ++L N+ L + K + D+S +K +E+ Sbjct: 13 GLGKGIAERLANDGFNIVLQDINEALLLETEKEFKEK--GYQAVAFKSDVSK-KKEQEEL 69 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA-PFM 399 V A + F +D M++NA + LE EE L F +NVFGT+ + A F+ Sbjct: 70 VQFAVTEFGQ--LDVMVNNAGVDAVTP-ILEIGEEELSKLFNINVFGTLFGIQAAANQFI 126 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 + G + S AG YSA+KH++ + + EL KGI Sbjct: 127 KQKSKGKIINACSIAGHESYEVLGTYSATKHSVRSFTQTAAKELADKGI 175
>DHB1_RAT (P51657) Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62)| (17-beta-HSD 1) (17-beta-hydroxysteroid dehydrogenase 1) Length = 344 Score = 50.8 bits (120), Expect = 2e-06 Identities = 39/122 (31%), Positives = 56/122 (45%), Gaps = 1/122 (0%) Frame = +1 Query: 157 PDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGL 333 P +E+L +D+ E V +A + + +D ++ NA R G LE E + Sbjct: 56 PPGSLEILELDVRDSES-----VAAARACVTEGRVDVLVCNAG--RGLFGPLEAHELNAV 108 Query: 334 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 513 A VNV GTI + + P M R G +V +S G + P +Y ASK AL G Sbjct: 109 GAVLDVNVLGTIRMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCE 168 Query: 514 SL 519 SL Sbjct: 169 SL 170
>DHRS3_BOVIN (O77769) Short-chain dehydrogenase/reductase 3 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) Length = 302 Score = 50.8 bits (120), Expect = 2e-06 Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 2/162 (1%) Frame = +1 Query: 40 RGIGEVLSMQFASLGA-KLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 RGIG L+ +FA GA K++L R ++ L+ I + + D + + Sbjct: 48 RGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFIC------DVGNRE 101 Query: 217 EVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 EV +A+++ G I +++NAA K ++ ++ L + +N G T+ P Sbjct: 102 EVYQTAKAVREKVGDITILVNNAAVVHGK-SLMDSDDDALPKSQHINTLGQFWTTKAFLP 160 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 519 ML+ GH V ++S PG Y SK + + SL Sbjct: 161 RMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>VIBA_VIBCH (Q56632) Vibriobactin-specific 2,3-dihydro-2,3-dihydroxybenzoate| dehydrogenase (EC 1.3.1.28) Length = 262 Score = 50.4 bits (119), Expect = 3e-06 Identities = 44/172 (25%), Positives = 78/172 (45%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ++RGIG + GA+++ + + L +++ ++PD ++ + +DL+ E Sbjct: 16 SARGIGFSVLEHLLQAGAQVMAADCEWQLLLEQSESLLGRYPD-QLTLKKLDLAEPEAVR 74 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++V AE + AG D+++ A E E + + F VN FG + + +A Sbjct: 75 EQVNQWAEQV---AGFDHLVCCAGILHVAP-LHEMPMEQVSSIFTVNAFGVLACMQGVAS 130 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M R G V++ S A P Y ASK AL+ + EL GI+ Sbjct: 131 SMKARQQGSMVIIGSNAANTPRMSIGAYGASKAALHMLVKCIGMELAPYGIR 182
>DHG1_BACME (P39482) Glucose 1-dehydrogenase 1 (EC 1.1.1.47) (GLCDH-I)| Length = 261 Score = 50.4 bits (119), Expect = 3e-06 Identities = 46/179 (25%), Positives = 83/179 (46%), Gaps = 7/179 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEE-----LERVKHNIMSKHPDSKVEVLPMDLSS 198 +S G+G+ ++++FA+ AK++++ R+KEE LE +K KV + + Sbjct: 15 SSTGLGKAMAIRFATEKAKVVVNYRSKEEEANSVLEEIK----------KVGGEAIAVKG 64 Query: 199 DEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 D +V++ +S G +D M++NA E P + E + N+ G Sbjct: 65 DVTVESDVINLVQSSIKEFGKLDVMINNAGMENPV-SSHEMSLSDWNKVIDTNLTGAFLG 123 Query: 376 TRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +R + ++ + G + MSS K+P P Y+ASK + +L E KGI+ Sbjct: 124 SREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
>PHBB_ZOORA (P23238) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 241 Score = 50.4 bits (119), Expect = 3e-06 Identities = 48/171 (28%), Positives = 75/171 (43%), Gaps = 1/171 (0%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 SRGIG +S+ + G K+ S A N + + K ++ + V D+SS E + Sbjct: 11 SRGIGAAISIALKAAGYKVAASYAGNDDAAKPFK-------AETGIAVYKWDVSSYEACV 63 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + + L ID +++NA + + T + A N+ G +T + Sbjct: 64 EGIAKVEADL---GPIDVLVNNAGITKDAMFH-KMTPDQWNAVINTNLTGLFNMTHPVWS 119 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M DR G V +SS G+ GQA YSA+K G+ +L E KGI Sbjct: 120 GMRDRSFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKALAQEGAAKGI 170
>DHK1_STRVN (P16542) Granaticin polyketide synthase putative ketoacyl reductase| 1 (EC 1.3.1.-) (ORF5) Length = 272 Score = 50.4 bits (119), Expect = 3e-06 Identities = 48/174 (27%), Positives = 80/174 (45%), Gaps = 3/174 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG ++ + A+LGA+ L AR++E L + + + D V + +D + Sbjct: 25 ATSGIGLAIARRLAALGARTFLCARDEERLAQTVKELRGEGFDVDGTVCDV---ADPAQI 81 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKA-TFKVNVFGTITLTR--L 384 + V +A + + +D +++NA R GA E + L N+ +T+ L Sbjct: 82 RAYVAAAVQRYGT--VDILVNNAG--RSGGGATAEIADELWLDVITTNLTSVFLMTKEVL 137 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 A ML + G + ++S GK YSASKH + G +L EL GI Sbjct: 138 NAGGMLAKKRGRIINIASTGGKQGVVHAVPYSASKHGVVGLTKALGLELARTGI 191
>DHRS3_HUMAN (O75911) Short-chain dehydrogenase/reductase 3 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (DD83.1) Length = 302 Score = 50.4 bits (119), Expect = 3e-06 Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 2/162 (1%) Frame = +1 Query: 40 RGIGEVLSMQFASLGA-KLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 RGIG L+ +FA GA K++L R ++ L+ I + + D + + Sbjct: 48 RGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFIC------DVGNRE 101 Query: 217 EVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 EV +A+++ G I +++NAA K ++ ++ L + +N G T+ P Sbjct: 102 EVYQTAKAVREKVGDITILVNNAAVVHGK-SLMDSDDDALLKSQHINTLGQFWTTKAFLP 160 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 519 ML+ GH V ++S PG Y SK + + SL Sbjct: 161 RMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>YHXC_BACSU (P40397) Hypothetical oxidoreductase yhxC (EC 1.-.-.-) (ORFX)| Length = 285 Score = 50.1 bits (118), Expect = 4e-06 Identities = 48/172 (27%), Positives = 85/172 (49%), Gaps = 3/172 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNK-EELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKE 219 GIG +S+ FA GA +++ N+ ++ E K + + K ++ D+ DE + Sbjct: 52 GIGRAVSVLFAKEGANVVIVYLNEHQDAEETKQYVEKE--GVKCLLIAGDVG-DEAFCND 108 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM 399 VV A +F S ID +++NAA + + + T L TF+ N+F LT+ + P Sbjct: 109 VVGQASQVFPS--IDILVNNAAEQHVQPSIEKITSHQLIRTFQTNIFSMFYLTKAVLPH- 165 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQAL--YSASKHALNGYFASLRSELCTKGIK 549 L +G ++++A+ + L YSA+K A+ + SL L +GI+ Sbjct: 166 LKKGSS---IINTASITAYKGNKTLIDYSATKGAIVTFTRSLSQSLVQQGIR 214
>DHR10_HUMAN (Q9BPX1) Dehydrogenase/reductase SDR family member 10 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase retSDR3) Length = 270 Score = 50.1 bits (118), Expect = 4e-06 Identities = 37/170 (21%), Positives = 80/170 (47%) Frame = +1 Query: 40 RGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKE 219 RGIG + F + GA++++ +++ ++ + P + + + D K+L Sbjct: 19 RGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL----PGAVFILCDVTQEDDVKTLV- 73 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM 399 +E++ +D +++NA P + E + +G + ++N+ GT TLT+L P+ Sbjct: 74 ----SETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPY- 128 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 L + G+ + +SS G + Y A+K A+ +L + G++ Sbjct: 129 LRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
>FABG_PSEAE (O54438) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 247 Score = 50.1 bits (118), Expect = 4e-06 Identities = 41/171 (23%), Positives = 76/171 (44%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG+ ++++ LGA +I +A + E++ + + + VL D+SSDE Sbjct: 13 ASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVL--DVSSDESVA 70 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + H + L +++NA R + +E N+ L++ + Sbjct: 71 ATLEHIQQHLGQPL---IVVNNAGITRDNLLVRMKDDEWFDVV-NTNLNSLYRLSKAVLR 126 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M G + + S G + GQ Y+A+K L G+ +L E+ ++ I Sbjct: 127 GMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAI 177
>YHDF_BACSU (O07575) Hypothetical oxidoreductase yhdF (EC 1.-.-.-)| Length = 289 Score = 49.7 bits (117), Expect = 6e-06 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 1/170 (0%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKL-ILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKE 219 GIG ++ FA GA + IL + E + I ++ + ++P D+ DE ++ Sbjct: 56 GIGRAAAIAFAKEGADISILYLDEHSDAEETRKRIEKENV--RCLLIPGDVG-DENHCEQ 112 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM 399 V F +D +++NAA + P+ L + E L+ TF+ N+F +T+ P Sbjct: 113 AVQQTVDHFGK--LDILVNNAAEQHPQDSILNISTEQLEKTFRTNIFSMFHMTKKALPH- 169 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 L G S A + T YS++K A+ + S+ L KGI+ Sbjct: 170 LQEGCAIINTTSITAYEGDT-ALIDYSSTKGAIVSFTRSMAKSLADKGIR 218
>YWFH_BACSU (P39644) Bacilysin biosynthesis oxidoreductase ywfH (EC 1.-.-.-)| Length = 259 Score = 49.7 bits (117), Expect = 6e-06 Identities = 26/82 (31%), Positives = 51/82 (62%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 AS+GIG+ ++++ A L++++RN + +E VK +I++KHP++ V VL D+ SD+ + Sbjct: 11 ASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAGDM-SDQHTR 69 Query: 214 KEVVHSAESLFSSAGIDYMMHN 279 + ES +D +++N Sbjct: 70 AGIFQKIES--QCGRLDVLINN 89
>DHRS3_MOUSE (O88876) Short-chain dehydrogenase/reductase 3 (EC 1.1.-.-)| (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) Length = 302 Score = 49.7 bits (117), Expect = 6e-06 Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 2/162 (1%) Frame = +1 Query: 40 RGIGEVLSMQFASLGA-KLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 RGIG L+ +FA GA K++L R ++ L+ I + + D + + Sbjct: 48 RGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFIC------DVGNRE 101 Query: 217 EVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 EV A+++ G I +++NAA K ++ ++ L + VN G T+ P Sbjct: 102 EVYQMAKAVREKVGDITILVNNAAVVHGK-SLMDSDDDALLKSQHVNTLGQFWTTKAFLP 160 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASL 519 ML+ GH V ++S PG Y SK + + SL Sbjct: 161 RMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>DHB1_HUMAN (P14061) Estradiol 17-beta-dehydrogenase 1 (EC 1.1.1.62)| (17-beta-HSD 1) (Placental 17-beta-hydroxysteroid dehydrogenase) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) Length = 327 Score = 49.7 bits (117), Expect = 6e-06 Identities = 41/131 (31%), Positives = 59/131 (45%), Gaps = 1/131 (0%) Frame = +1 Query: 157 PDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEET-EEGL 333 P +E L +D+ D KS V +A + +D ++ NA G LE E+ + Sbjct: 55 PPGSLETLQLDVR-DSKS----VAAARERVTEGRVDVLVCNAGLGL--LGPLEALGEDAV 107 Query: 334 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 513 + VNV GT+ + + P M RG G +V S G + P +Y ASK AL G Sbjct: 108 ASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCE 167 Query: 514 SLRSELCTKGI 546 SL L G+ Sbjct: 168 SLAVLLLPFGV 178
>HDHA_ECOLI (P0AET8) 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159)| (7-alpha-HSDH) Length = 255 Score = 49.7 bits (117), Expect = 6e-06 Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A GIG+ +++ FA+ GA +++S N + V I + D++S++ Sbjct: 19 AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFACRCDITSEQ--- 73 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 E+ A+ S G +D +++NA PK + + + +++NVF L++L+A Sbjct: 74 -ELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHLSQLVA 130 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P M G G + ++S A + Y++SK A + ++ +L K I+ Sbjct: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183
>HDHA_ECO57 (P0AET9) 7-alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159)| (7-alpha-HSDH) Length = 255 Score = 49.7 bits (117), Expect = 6e-06 Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A GIG+ +++ FA+ GA +++S N + V I + D++S++ Sbjct: 19 AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFACRCDITSEQ--- 73 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 E+ A+ S G +D +++NA PK + + + +++NVF L++L+A Sbjct: 74 -ELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHLSQLVA 130 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P M G G + ++S A + Y++SK A + ++ +L K I+ Sbjct: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183
>FOX2_YEAST (Q02207) Peroxisomal hydratase-dehydrogenase-epimerase (HDE)| (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.-); D-3-hydroxyacyl CoA dehydrogenase (EC 1.1.1.-)] Length = 900 Score = 49.7 bits (117), Expect = 6e-06 Identities = 46/176 (26%), Positives = 85/176 (48%), Gaps = 5/176 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNK-----EELERVKHNIMSKHPDSKVEVLPMDLSS 198 A G+G+ ++ FA GAK++++ EE+ ++ + + PDS V L Sbjct: 330 AGGGLGKSHAIWFARYGAKVVVNDIKDPFSVVEEINKL-YGEGTAIPDSHDVVTEAPL-- 386 Query: 199 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 ++ +A S F +D +++NA R K L+ +E A KV++F T +L+ Sbjct: 387 -------IIQTAISKFQR--VDILVNNAGILRDK-SFLKMKDEEWFAVLKVHLFSTFSLS 436 Query: 379 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 + + P + G + +S +G GQA Y+A+K A+ G+ ++ E +GI Sbjct: 437 KAVWPIFTKQKSGFIINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGI 492 Score = 48.5 bits (114), Expect = 1e-05 Identities = 47/170 (27%), Positives = 77/170 (45%), Gaps = 5/170 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A G+G+V ++ +AS GAK++++ L HN SK D V+ + + Sbjct: 17 AGGGLGKVYALAYASRGAKVVVNDLGGT-LGGSGHN--SKAADLVVDEIKKAGGIAVANY 73 Query: 214 KEVVHSAESLFSSA-----GIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 V + E + +A +D +++NA R A + TE + V++ G L+ Sbjct: 74 DSVNENGEKIIETAIKEFGRVDVLINNAGILRDVSFA-KMTEREFASVVDVHLTGGYKLS 132 Query: 379 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 R P+M + G + +S AG GQA YSA+K L G +L E Sbjct: 133 RAAWPYMRSQKFGRIINTASPAGLFGNFGQANYSAAKMGLVGLAETLAKE 182
>BPHB_PSEPU (P72220) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 277 Score = 49.7 bits (117), Expect = 6e-06 Identities = 46/168 (27%), Positives = 78/168 (46%), Gaps = 5/168 (2%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G L +F + AK+ + ++ E L +++ + H D+ + V + D +SL++ Sbjct: 16 GLGRALVDRFVAERAKVAVLDKSAERLAQLE----TDHGDNVLGV-----TGDVRSLEDQ 66 Query: 223 VHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFK----VNVFGTITLTRLL 387 +A + G ID ++ NA ++ EE L A F +NV G I + Sbjct: 67 KQAASRCVAKFGKIDTLIPNAGIWDYSTALIDLPEESLDAAFDEVFHINVKGYIHAVKAC 126 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P ++ G+ + S AG P G LY+A+KHA+ G L EL Sbjct: 127 LPALV-ASRGNVIFTISNAGFYPNGGGPLYTAAKHAVVGLVRELAFEL 173
>PGDH_HUMAN (P15428) 15-hydroxyprostaglandin dehydrogenase [NAD+] (EC| 1.1.1.141) (PGDH) (Prostaglandin dehydrogenase 1) Length = 266 Score = 49.3 bits (116), Expect = 7e-06 Identities = 44/177 (24%), Positives = 79/177 (44%), Gaps = 5/177 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A++GIG + GAK+ L N E + K + + K + D++ D++ L Sbjct: 13 AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA-DQQQL 71 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ F +D +++NA E+ + T ++N+ I+ T L Sbjct: 72 RDTFRKVVDHFGR--LDILVNNAGVNN---------EKNWEKTLQINLVSVISGTYLGLD 120 Query: 394 FMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKHALNGY--FASLRSELCTKGIK 549 +M + G + MSS AG +P Q +Y ASKH + G+ A+L + L G++ Sbjct: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
>FBP2_DROME (P54398) Fat body protein 2 (Fat body protein P6)| Length = 256 Score = 49.3 bits (116), Expect = 7e-06 Identities = 44/166 (26%), Positives = 79/166 (47%), Gaps = 3/166 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG + MQ K++ E +E +K + + +P KV + M+L ++ S+++ Sbjct: 17 GIGWQMMMQLMQKDIKMMGIMHRMENVEMMK-KLQAINPSVKVVFMQMNLM-EKMSIEQA 74 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM- 399 + + ID M++ G L ++ ++ T +N+ G I T + P+M Sbjct: 75 MKKMGQMMGH--IDVMING-------EGVL--LDKDVETTMGMNLTGMIQSTMMAMPYMD 123 Query: 400 -LDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 GMG VV MSS G P P A+Y+A+ H + G+ S+ ++ Sbjct: 124 KTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKM 169
>DHI2_SHEEP (P50168) Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC| 1.1.1.-) (11-DH2) (11-beta-hydroxysteroid dehydrogenase type 2) (11-beta-HSD2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) Length = 427 Score = 48.9 bits (115), Expect = 9e-06 Identities = 41/133 (30%), Positives = 66/133 (49%), Gaps = 4/133 (3%) Frame = +1 Query: 163 SKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKAT 342 S++++L MDL+ + V+ + +S G+ +++NA + + + E AT Sbjct: 130 SRLQLLQMDLTKPA-DISRVLEFTKVHTASTGLWGLVNNAG----QNIFVADAELCPVAT 184 Query: 343 FK----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 510 F+ VN FG + +T+ L P +L R G V +SS AG +P P A Y SK AL Sbjct: 185 FRTCMEVNFFGALEMTKGLLP-LLRRSSGRIVTVSSPAGDMPFPCLAAYGTSKAALALLM 243 Query: 511 ASLRSELCTKGIK 549 + EL G+K Sbjct: 244 GNFSCELLPWGVK 256
>FOX2_CANTR (P22414) Peroxisomal hydratase-dehydrogenase-epimerase (HDE)| (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.-); D-3-hydroxyacyl CoA dehydrogenase (EC 1.1.1.-)] Length = 906 Score = 48.9 bits (115), Expect = 9e-06 Identities = 43/175 (24%), Positives = 83/175 (47%), Gaps = 3/175 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNK--EELERVKHNIMSKHPDSKVEVLPMDLSSDEK 207 A G+G+ + FA GAK++++ + ++ +K PD D++ D + Sbjct: 330 AGAGLGKEYAKWFAKYGAKVVVNDFKDATKTVDEIKAAGGEAWPDQH------DVAKDSE 383 Query: 208 SL-KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRL 384 ++ K V+ + ID +++NA R + A +E + +V++ GT L+RL Sbjct: 384 AIIKNVIDKYGT------IDILVNNAGILRDRSFAKMSKQEW-DSVQQVHLIGTFNLSRL 436 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P+ +++ G + ++S +G GQA YS+SK + G ++ E IK Sbjct: 437 AWPYFVEKQFGRIINITSTSGIYGNFGQANYSSSKAGILGLSKTMAIEGAKNNIK 491 Score = 47.4 bits (111), Expect = 3e-05 Identities = 48/181 (26%), Positives = 81/181 (44%), Gaps = 9/181 (4%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS---------ARNKEELERVKHNIMSKHPDSKVEVLPM 186 A G+G+ S++FA LGAK++++ N + + V I+ K+ V Sbjct: 16 AGGGLGKYYSLEFAKLGAKVVVNDLGGALNGQGGNSKAADVVVDEIV-KNGGVAVADYNN 74 Query: 187 DLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGT 366 L D ++V +A F + + +++NA R + TE+ K V++ G Sbjct: 75 VLDGD-----KIVETAVKNFGT--VHVIINNAGILR-DASMKKMTEKDYKLVIDVHLNGA 126 Query: 367 ITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 +T+ P+ + G V SS AG GQA Y+++K AL G+ +L E I Sbjct: 127 FAVTKAAWPYFQKQKYGRIVNTSSPAGLYGNFGQANYASAKSALLGFAETLAKEGAKYNI 186 Query: 547 K 549 K Sbjct: 187 K 187
>DHG_BACSU (P12310) Glucose 1-dehydrogenase (EC 1.1.1.47)| Length = 261 Score = 48.9 bits (115), Expect = 9e-06 Identities = 46/177 (25%), Positives = 87/177 (49%), Gaps = 5/177 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSA-RNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 A+ G+G+ ++++F AK++++ NK++ VK ++ + V+ D++ +E Sbjct: 15 AASGLGKAMAIRFGKEQAKVVINYYSNKQDPNEVKEEVIKA--GGEAVVVQGDVTKEE-D 71 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKV---NVFGTITLTR 381 +K +V +A F + +D M++NA E P + E LK KV N+ G +R Sbjct: 72 VKNIVQTAIKEFGT--LDIMINNAGLENP----VPSHEMPLKDWDKVIGTNLTGAFLGSR 125 Query: 382 LLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + ++ + G+ + MSS +P P Y+ASK + +L E KGI+ Sbjct: 126 EAIKYFVENDIKGNVINMSSVHEVIPWPLFVHYAASKGGIKLMTETLALEYAPKGIR 182
>DHG_BACME (P40288) Glucose 1-dehydrogenase (EC 1.1.1.47)| Length = 261 Score = 48.9 bits (115), Expect = 9e-06 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 7/179 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEE-----LERVKHNIMSKHPDSKVEVLPMDLSS 198 +S G+G+ ++++FA+ AK++++ R+KE+ LE +K KV + + Sbjct: 15 SSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIK----------KVGGEAIAVKG 64 Query: 199 DEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITL 375 D +V++ +S G +D M++NA E P + E + N+ G Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPV-SSHEMSLSDWNKVIDTNLTGAFLG 123 Query: 376 TRLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +R + ++ + G + MSS K+P P Y+ASK + +L E KGI+ Sbjct: 124 SREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
>Y4LA_RHISN (P55541) Putative short-chain type dehydrogenase/reductase y4lA (EC| 1.-.-.-) Length = 278 Score = 48.9 bits (115), Expect = 9e-06 Identities = 45/179 (25%), Positives = 85/179 (47%), Gaps = 3/179 (1%) Frame = +1 Query: 1 RHEARLCG*RXASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 180 R E ++ A GIG+ ++ A G +++++ + I ++ ++ + Sbjct: 3 RFEGKVAVVTGAGAGIGKACALAIAREGGRVVVADLDGSAAIACTAQIAAEAGNALA--M 60 Query: 181 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFER--PKRGALEETEEGL-KATFKV 351 MD++ D +++ + +AE F G+D +++NA+ P+ A+ + + + T Sbjct: 61 AMDIA-DAQAVAALFETAERHFG--GVDLLVNNASAMHLTPRDRAILDLDLAVWDQTMAT 117 Query: 352 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 N+ GT+ R P M+ RG G V MSS G Q Y+ SK A+N ASL ++ Sbjct: 118 NLRGTLLCCRQAIPRMIARGGGAIVNMSSCQGLSGDTAQTSYAVSKAAMNMLSASLATQ 176
>FABG_CHLMU (Q9PKF7) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 248 Score = 48.9 bits (115), Expect = 9e-06 Identities = 44/171 (25%), Positives = 78/171 (45%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 SRGIG ++ FA GA + + N+E + ++ K SKV +D+S ++ Sbjct: 16 SRGIGFGIAKLFAEHGANVQIWGINEEAGKSAAQDLSDK-TGSKVSFALVDVSKNDMVSA 74 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 +V + L ID +++NA R + +EE + N+ + + Sbjct: 75 QV---QKFLAEYGTIDVVVNNAGITRDSL-LMRMSEEEWSSVIDTNLGSIYNVCSAVIRP 130 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M+ G V +SS G +PGQ Y+A+K + G+ +L E+ +K I+ Sbjct: 131 MIKARSGAIVNISSIVGLRGSPGQTNYAAAKAGIIGFSKALSKEVGSKNIR 181
>KDUD_BACSU (P50842) 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)| (2-keto-3-deoxygluconate oxidoreductase) Length = 254 Score = 48.9 bits (115), Expect = 9e-06 Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 3/172 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG+ ++ A GA +I ++ E + + + +D+S E + Sbjct: 23 GIGQGIAKALAGAGADIIGTSHTSSLSETQQ---LVEQEGRIFTSFTLDMSKPEA----I 75 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 SA LF + ID +++NA ++ A + EE + VN+ LT+L ML Sbjct: 76 KDSAAELFENRQIDILVNNAGIIHREK-AEDFPEENWQHVLNVNLNSLFILTQLAGRHML 134 Query: 403 DRGMGHFVVMSSAA---GKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 RG G + ++S G + P Y+ASKHA+ G S +E GI+ Sbjct: 135 KRGHGKIINIASLLSFQGGILVPA---YTASKHAVAGLTKSFANEWAASGIQ 183
>LINX_PSEPA (P50198) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (EC| 1.1.1.-) (2,5-DDOL dehydrogenase) Length = 250 Score = 48.9 bits (115), Expect = 9e-06 Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 1/170 (0%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSK-VEVLPMDLSSDEKSLKE 219 G+G + +FA GAK+++ N+E + V I + D+ + + D +S ++ Sbjct: 18 GLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFIRLDVTDAASWNNAIAA 77 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM 399 V L + + ++H FE EE+ EG VN + P + Sbjct: 78 AVDGFGGLTTLSNTAGIIHPGGFE-------EESIEGWNKMVAVNQTAIFLGIKAAIPEL 130 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G G + +SS G PT G A Y A+K A+ + E +G++ Sbjct: 131 VKSGNGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAALEFVDRGVR 180
>SPRE_MOUSE (Q64105) Sepiapterin reductase (EC 1.1.1.153) (SPR)| Length = 261 Score = 48.5 bits (114), Expect = 1e-05 Identities = 49/184 (26%), Positives = 85/184 (46%), Gaps = 13/184 (7%) Frame = +1 Query: 16 LCG*RXASRGIGEVLSMQFASL---GAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 186 +C ASRG G L+ Q A L G+ +++SAR++ L ++K + ++ PD KV + Sbjct: 10 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 69 Query: 187 DLSSDEKSLKEVVHSAESLFSSAGID--YMMHNAAFERPKRGALEETEEGLKATFKVNVF 360 DL + E ++ ++ + L G+ +++NAA G + + + +VN + Sbjct: 70 DLGT-EAGVQRLLSAVRELPRPEGLQRLLLINNAA----TLGDVSKGFLNVNDLAEVNNY 124 Query: 361 GTITLTRLLA-------PFMLDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGYFAS 516 + LT +L F G+ VV +SS P G LY A K A + + Sbjct: 125 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 184 Query: 517 LRSE 528 L +E Sbjct: 185 LAAE 188
>DHG2_BACME (P39483) Glucose 1-dehydrogenase 2 (EC 1.1.1.47) (GLCDH-II)| Length = 261 Score = 48.5 bits (114), Expect = 1e-05 Identities = 44/174 (25%), Positives = 83/174 (47%), Gaps = 3/174 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSAR-NKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 S+G+G ++++F +K++++ R N+EE VK I + + ++ D++ +E Sbjct: 16 SKGLGRAMAVRFGQEQSKVVVNYRSNEEEALEVKKEI--EEAGGQAIIVRGDVTKEE--- 70 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 +VV+ E+ G +D M++NA E P E + E N+ G +R Sbjct: 71 -DVVNLVETAVKEFGSLDVMINNAGVENPVPSH-ELSLENWNQVIDTNLTGAFLGSREAI 128 Query: 391 PFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + ++ + G+ + MSS +P P Y+ASK + +L E KGI+ Sbjct: 129 KYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
>DHB3_RAT (O54939) Estradiol 17-beta-dehydrogenase 3 (EC 1.1.1.62)| (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase) Length = 306 Score = 48.5 bits (114), Expect = 1e-05 Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A GIG+ S + A G ++L +R E+L+ + I + S+V+V+ D + ++ Sbjct: 52 AGDGIGKAYSFELARHGLNVVLISRTLEKLQVISEEI-ERTTGSRVKVVQADFTRED--- 107 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAF-ERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + E I +++N T ++ N+ + +T+L+ Sbjct: 108 --IYDHIEEQLKGLEIGVLVNNVGMLPNLLPSHFLSTSGESQSVIHCNITSVVKMTQLVL 165 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M R G + +SS G P P +LYSASK + + +L E KGI Sbjct: 166 KHMESRRRGLILNISSGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGI 217
>DHI2_RAT (P50233) Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC| 1.1.1.-) (11-DH2) (11-beta-hydroxysteroid dehydrogenase type 2) (11-beta-HSD2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) Length = 400 Score = 47.8 bits (112), Expect = 2e-05 Identities = 36/128 (28%), Positives = 59/128 (46%) Frame = +1 Query: 166 KVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATF 345 ++++L MDL+ E + V+ ++ +S G+ +++NA + Sbjct: 131 RLKLLQMDLTKPE-DISRVLEITKAHTASTGLWGLVNNAGLNMVVADVELSPVVTFRECM 189 Query: 346 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 525 +VN FG + LT+ L P +L G V + S AG +P P A Y SK A+ + Sbjct: 190 EVNFFGALELTKGLLP-LLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMDTFSC 248 Query: 526 ELCTKGIK 549 EL GIK Sbjct: 249 ELLPWGIK 256
>BPHB_COMTE (Q46381) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 281 Score = 47.8 bits (112), Expect = 2e-05 Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 5/168 (2%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G L +F + GA++ + ++ E L ++ H + V V+ D +SL++ Sbjct: 16 GLGRALVDRFVAEGARVAVLDKSAERLRELE----VAHGGNAVGVV-----GDVRSLQDQ 66 Query: 223 VHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFK----VNVFGTITLTRLL 387 +AE ++ G ID ++ NA + E+ + A F VNV G I + Sbjct: 67 KRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYIHAVKAC 126 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P ++ G V S AG P G LY+A+KHA+ G + EL Sbjct: 127 LPALVS-SRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFEL 173
>PHBB_RHIME (P50205) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 241 Score = 47.8 bits (112), Expect = 2e-05 Identities = 45/170 (26%), Positives = 69/170 (40%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 SRGIG + + + G K+ + +E + +S + V D+SS + + Sbjct: 11 SRGIGAAICVALKAAGYKVAANYAGNDERAKAFEQ------ESGIPVYKWDVSSYQACVD 64 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 + L +D +++NA R + T E N+ G +T L Sbjct: 65 GIARVEADL---GPVDILVNNAGITRDAMFH-KMTPEQWGEVIGTNLTGVFNMTHPLWSG 120 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M DRG G V +SS G+ GQ YSA+K G +L E KGI Sbjct: 121 MRDRGFGRIVNISSINGQKGQMGQVNYSAAKAGDLGLTKALAQEGAAKGI 170
>DHI2_MOUSE (P51661) Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC| 1.1.1.-) (11-DH2) (11-beta-hydroxysteroid dehydrogenase type 2) (11-beta-HSD2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) Length = 386 Score = 47.8 bits (112), Expect = 2e-05 Identities = 40/132 (30%), Positives = 64/132 (48%), Gaps = 4/132 (3%) Frame = +1 Query: 166 KVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATF 345 ++++L MDL+ E + V+ ++ +S G+ +++NA + + E ATF Sbjct: 131 RLKLLQMDLTKAE-DISRVLEITKAHTASTGLWGLVNNAGLNI----VVADVELSPVATF 185 Query: 346 K----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 513 + VN FG + LT+ L P +L G V + S AG +P P A Y SK A+ Sbjct: 186 RKCMEVNFFGALELTKGLLP-LLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMD 244 Query: 514 SLRSELCTKGIK 549 + EL GIK Sbjct: 245 TFGCELLPWGIK 256
>HCDR_XANP2 (Q56840) 2-(R)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.268)| (R-HPCDH) (Aliphatic epoxide carboxylation component III) Length = 249 Score = 47.4 bits (111), Expect = 3e-05 Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 5/177 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLG---AKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE 204 AS G G ++ +F + G A L LSA EE R + + KV + D++ DE Sbjct: 9 ASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYA----DKVLRVRADVA-DE 63 Query: 205 KSLKEVVHSAESLFSSAGIDYMMHNAAFE-RPKRGALEETE-EGLKATFKVNVFGTITLT 378 + + + F + ID +++NA + G L T E VNV G Sbjct: 64 GDVNAAIAATMEQFGA--IDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 121 Query: 379 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 R + P ML +G G V ++S A V PG++ Y+ SK A+ S+ + GI+ Sbjct: 122 RAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIR 178
>YD1F_SCHPO (Q10245) Hypothetical oxidoreductase C4G9.15 in chromosome I (EC| 1.-.-.-) Length = 341 Score = 47.4 bits (111), Expect = 3e-05 Identities = 43/180 (23%), Positives = 80/180 (44%), Gaps = 9/180 (5%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSD-EKS 210 A+ GIG+ + Q A G ++L +R +E+L+ ++K ++ +V ++ D K+ Sbjct: 65 ATDGIGKEYATQLAMSGFNVVLISRTQEKLDA-----LAKELETVAKVKTRTIAIDYTKT 119 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLL 387 E I +++N + ET + + +N FGT+ T+ + Sbjct: 120 TAETFEKLHQDLVGTPITVLINNVGQSHYMPTSFAETTVKEMDDIMHINCFGTLHTTKAV 179 Query: 388 APFMLDRGMGH-------FVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 ML + + M S AG +P+P + Y+ SK L+ + ASL E+ +GI Sbjct: 180 LSIMLRERQKNEKGPRCLILTMGSFAGLLPSPYLSTYAGSKAFLSNWSASLGEEVKKQGI 239
>FABG_BUCAP (Q8K9J5) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 47.4 bits (111), Expect = 3e-05 Identities = 37/171 (21%), Positives = 80/171 (46%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A++G+G+ ++++ + G ++I ++ + ++ + +K+ +DL + L Sbjct: 13 ANQGLGKEIAIKLSQKGIQVIGTSTTVDGVKTI-----NKYLKKNGFGFILDLKDTDSIL 67 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +++ + +S ID +++NA +E + K+N+ +++ + Sbjct: 68 EKMKEICQKKYS---IDILINNAGITSDNLLVYMSNKEW-ENVIKINLTSVFYMSKSVIR 123 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G V + S G + GQ YSASK L G+ SL E+ KGI Sbjct: 124 SMIKKRYGRIVTIGSVIGYLGNRGQINYSASKSGLIGFHKSLALEVAQKGI 174
>DHI2_BOVIN (O77667) Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC| 1.1.1.-) (11-DH2) (11-beta-hydroxysteroid dehydrogenase type 2) (11-beta-HSD2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) Length = 404 Score = 47.4 bits (111), Expect = 3e-05 Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 4/133 (3%) Frame = +1 Query: 163 SKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKAT 342 S++++L MDL+ + V+ + S G+ +++NA + + + E AT Sbjct: 130 SRLKLLQMDLTKPG-DISRVLEFTKVHTPSTGLWGLVNNAG----QNIFVADAELCPVAT 184 Query: 343 FK----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYF 510 F+ VN FG + +T+ L P +L R G V +SS AG +P P A Y SK AL Sbjct: 185 FRTCMEVNFFGALEMTKGLLP-LLRRSSGRIVTVSSPAGDMPFPCLAAYGTSKAALALLM 243 Query: 511 ASLRSELCTKGIK 549 + EL G+K Sbjct: 244 GNFSCELLPWGVK 256
>FABG_BUCAI (P57432) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 47.0 bits (110), Expect = 4e-05 Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 3/174 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE-KS 210 A++GIG+ ++ + G ++I ++ ++ ++R+ + + + +D +++ + Sbjct: 13 ANQGIGKAIAKKLIKKGIQVIGTSTTEDGVKRINDYLEGNGFGFVLNLKNIDSITEKIQE 72 Query: 211 LKEVVHSAESLFSSAGI--DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRL 384 + + HS + L ++AGI D ++ N ++ TE K N+ L + Sbjct: 73 IYKKKHSIDILINNAGIKEDNLLVN----------MKSTE--WDDVIKTNLSSVFHLVKS 120 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 + M+ + G + + S GQ YSASK L G+ SL E+ +KGI Sbjct: 121 VIRSMIKKRQGRIITIGSVIAYTGNKGQVNYSASKSGLIGFHKSLALEVASKGI 174
>DHRS6_MOUSE (Q8JZV9) Dehydrogenase/reductase SDR family member 6 precursor (EC| 1.1.-.-) Length = 245 Score = 47.0 bits (110), Expect = 4e-05 Identities = 40/173 (23%), Positives = 77/173 (44%), Gaps = 1/173 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A++GIG ++ FA GAK+I + N+ +L+ + + + VL + Sbjct: 14 AAQGIGRASALAFAREGAKVIATDINESKLQE-----LESYRGIQTRVLDVTKKRQIDQF 68 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + + LF+ AG +H+ L+ E+ + +NV + + P Sbjct: 69 ASEIERIDVLFNVAG---FVHHGTI-------LDCEEKDWDFSMNLNVRSMFLMIKAFLP 118 Query: 394 FMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGYFASLRSELCTKGIK 549 ML + G+ + MSS A + + +YSA+K A+ G S+ ++ +GI+ Sbjct: 119 KMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIR 171
>Y2146_BRAJA (Q45219) Probable short-chain type dehydrogenase/reductase blr2146| (EC 1.-.-.-) Length = 281 Score = 47.0 bits (110), Expect = 4e-05 Identities = 46/179 (25%), Positives = 84/179 (46%), Gaps = 3/179 (1%) Frame = +1 Query: 1 RHEARLCG*RXASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 180 R E ++ A GIG+ ++ A G +++++ + I ++ + L Sbjct: 3 RFEGKVAVVTGAGAGIGKACALAIAREGGRVVVADIDGSAAIACTAQIAAEAGHALA--L 60 Query: 181 PMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFER--PKRGALEETEEGL-KATFKV 351 +D++ D +++ + +AE F G+D +++NA+ P+ A+ E E + T Sbjct: 61 AIDIA-DAQAVAALFETAERHFG--GVDLLVNNASAMHLTPRDRAILELELAVWDQTMAT 117 Query: 352 NVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 N+ GT+ R P M+ RG G V MSS G Y+ASK A+N +SL ++ Sbjct: 118 NLRGTLLCCRQAIPRMIARGGGAIVNMSSCQGLSGDTALTSYAASKAAMNMLSSSLATQ 176
>SDH_AGRT5 (Q8U8I2) Serine 3-dehydrogenase (EC 1.1.1.276)| Length = 249 Score = 46.6 bits (109), Expect = 5e-05 Identities = 40/172 (23%), Positives = 75/172 (43%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ G G+ + +F G K+I + R E LE + + ++ +DE + Sbjct: 10 ATSGFGQATARRFVKEGWKVIGTGRRAERLEALAAELGQAFHGIAFDI------TDEDAT 63 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 ++ + + F ID +++NA A + + + N+ G + +T L P Sbjct: 64 EKALAALPDGFRD--IDILVNNAGLALGTAPAPQVALKDWQTMVDTNITGLLNITHHLLP 121 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 ++ + G V +SS A P G +Y +K L + LRS+L KG++ Sbjct: 122 TLIKQ-KGIVVNLSSVAAHYPYLGGNVYGGTKAFLRQFSLGLRSDLHGKGVR 172
>MTDH_AGABI (O93868) NADP-dependent mannitol dehydrogenase (EC 1.1.1.138)| (MtDH) (Mannitol 2-dehydrogenase [NADP+]) Length = 261 Score = 46.6 bits (109), Expect = 5e-05 Identities = 46/179 (25%), Positives = 76/179 (42%), Gaps = 8/179 (4%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 +RGIG + A+ GA + + R+ ++ V + K K + D+S+ + K Sbjct: 19 NRGIGLAFTRAVAAAGANVAVIYRSAKDAVEVTEKV-GKEFGVKTKAYQCDVSNTDIVTK 77 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 + L + +G+ + NA K A E T E K + VNVFG R +A Sbjct: 78 TIQQIDADLGAISGL---IANAGVSVVKP-ATELTHEDFKFVYDVNVFGVFNTCRAVAKL 133 Query: 397 MLDRGM-GHFVVMSSAAGKVPTPG-------QALYSASKHALNGYFASLRSELCTKGIK 549 L + G VV SS + ++ Q Y++SK A + L +E + GI+ Sbjct: 134 WLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEWASAGIR 192
>DHB3_HUMAN (P37058) Estradiol 17-beta-dehydrogenase 3 (EC 1.1.1.62)| (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase) Length = 310 Score = 46.2 bits (108), Expect = 6e-05 Identities = 42/175 (24%), Positives = 81/175 (46%), Gaps = 4/175 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE--K 207 A GIG+ S + A G ++L +R E+LE + I + V+++ D + D+ + Sbjct: 56 AGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEI-ERTTGRSVKIIQADFTKDDIYE 114 Query: 208 SLKEVVHSAES--LFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 +KE + E L ++ G+ + + F L +E +++ N+ + +T+ Sbjct: 115 HIKEKLAGLEIGILVNNVGMLPNLLPSHF-------LNAPDE-IQSLIHCNITSVVKMTQ 166 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 L+ M R G + +SS P P ++YSASK + + +L+ E K + Sbjct: 167 LILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEV 221
>MAS1_AGRT9 (P50202) Agropine synthesis reductase (EC 1.-.-.-)| Length = 430 Score = 46.2 bits (108), Expect = 6e-05 Identities = 37/156 (23%), Positives = 73/156 (46%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 +RGIG+ ++ G ++ L ARN ++L + ++ + L D S+K Sbjct: 208 TRGIGKAIAEDLIRHGYRVSLGARNIQDLVAAFGDENEALHYARFDAL------DHSSMK 261 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 + V + + F+ ID +++NA E E L+ + +N + +T+L P+ Sbjct: 262 DWVDTTIAKFNR--IDGLVNNAGCGDHVDLEKEINVELLQKQWDINCVAPLIMTKLCMPY 319 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNG 504 +++ G G V ++S +G+ Y+ +KH L G Sbjct: 320 LIESGSGRIVNLNSMSGQRVANSLVGYNMTKHGLAG 355
>DHI2_RABIT (P51976) Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC| 1.1.1.-) (11-DH2) (11-beta-hydroxysteroid dehydrogenase type 2) (11-beta-HSD2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) Length = 406 Score = 46.2 bits (108), Expect = 6e-05 Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 4/132 (3%) Frame = +1 Query: 166 KVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATF 345 ++++L MDL+ + + ++ +S G+ +++NA + + E ATF Sbjct: 131 RLKLLQMDLTKPA-DISRALEFTKAHTTSTGLWGLVNNAGHN----DVVADVELSPVATF 185 Query: 346 K----VNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 513 + VN FG + LT+ L P +L G V + S AG++P P A Y SK A+ Sbjct: 186 RNCMEVNFFGALELTKGLLP-LLHHSRGRIVTLGSPAGEMPYPCLAAYGTSKAAMALLMD 244 Query: 514 SLRSELCTKGIK 549 + EL G+K Sbjct: 245 AFSCELLPWGVK 256
>LINC_PSEPA (P50197) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (EC| 1.1.1.-) (2,5-DDOL dehydrogenase) Length = 250 Score = 46.2 bits (108), Expect = 6e-05 Identities = 44/170 (25%), Positives = 74/170 (43%), Gaps = 1/170 (0%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG + GA + ++ N E E V K + ++ + E+ +K + Sbjct: 17 GIGRATVELLVASGANVPVADINDEAGEAVVATSGGKAAYFRCDI------AQEEDVKAL 70 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 V A++L + G+D +NAA + E + E + + +NV GT + M+ Sbjct: 71 V--AQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTGTFLCMKYQILAMI 128 Query: 403 DRG-MGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 +RG G V +SAAG V P Y +KHA+ G ++ GI+ Sbjct: 129 ERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAAADYGKHGIR 178
>DHGB_BACME (P07999) Glucose 1-dehydrogenase B (EC 1.1.1.47)| Length = 262 Score = 46.2 bits (108), Expect = 6e-05 Identities = 43/175 (24%), Positives = 83/175 (47%), Gaps = 3/175 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 +S G+G+ ++++FA+ AK++++ R+KE+ + N + + KV + + D Sbjct: 15 SSTGLGKSMAIRFATEKAKVVVNYRSKED----EANSVLEEEIKKVGGEAIAVKGDVTVE 70 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 +V++ +S G +D M++NA E P + E + N+ G +R Sbjct: 71 SDVINLVQSAIKEFGKLDVMINNAGMENPV-SSHEMSLSDWNKVIDTNLTGAFLGSREAI 129 Query: 391 PFMLDRGM-GHFVVMSSA-AGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + ++ + G + MSS K+P P Y+ASK + +L E KGI+ Sbjct: 130 KYFVENDIKGTVINMSSVHEWKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 184
>FABG2_BRANA (Q93X67) 3-oxoacyl-[acyl-carrier-protein] reductase 2, chloroplast| precursor (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase 2) Length = 328 Score = 45.8 bits (107), Expect = 8e-05 Identities = 39/172 (22%), Positives = 80/172 (46%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ +++ G K++++ AR+ +E E+V I + + D+S E Sbjct: 93 ASRGIGKAIALSLGKAGCKVLVNYARSAKEAEQVSKQIEAY--GGQAITFGGDVSK-EAD 149 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + ++ +A + + ID +++NA R + + +N+ G T+ Sbjct: 150 VDAMMKTAVDAWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNLTGVFLCTQAAT 206 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + ++S G + GQA Y+A+K + G+ + E ++ I Sbjct: 207 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNI 258
>FABG1_BRANA (Q93X62) 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplast| precursor (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase 1) (Beta-keto acyl-carrier protein reductase 1) Length = 320 Score = 45.8 bits (107), Expect = 8e-05 Identities = 39/172 (22%), Positives = 80/172 (46%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ +++ G K++++ AR+ +E E V I + + D+S E Sbjct: 85 ASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQIEAY--GGQAITFGGDVSK-EAD 141 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 ++ ++ +A + + ID +++NA R + + +N+ G T+ Sbjct: 142 VEAMMKTAIDAWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNLTGVFLCTQAAT 198 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + ++S G + GQA Y+A+K + G+ + E ++ I Sbjct: 199 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNI 250
>FABG3_BRANA (Q949M3) 3-oxoacyl-[acyl-carrier-protein] reductase 3, chloroplast| precursor (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase 3) Length = 315 Score = 45.8 bits (107), Expect = 8e-05 Identities = 39/172 (22%), Positives = 80/172 (46%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ +++ G K++++ AR+ +E E V I + + D+S E Sbjct: 80 ASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQIEAY--GGQAITFGGDVSK-EAD 136 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 ++ ++ +A + + ID +++NA R + + +N+ G T+ Sbjct: 137 VEAMMKTAIDAWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNLTGVFLCTQAAT 193 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + ++S G + GQA Y+A+K + G+ + E ++ I Sbjct: 194 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNI 245
>YOHF_ECOLI (P33368) Hypothetical oxidoreductase yohF (EC 1.-.-.-)| Length = 253 Score = 45.8 bits (107), Expect = 8e-05 Identities = 42/165 (25%), Positives = 78/165 (47%), Gaps = 2/165 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG+ ++ A G + ++ + EE + + H + E++ +DL + L E Sbjct: 13 GIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSH-GVRAEIVQLDLGN----LPEG 67 Query: 223 VHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM 399 + E L G ID +++NA K L+ + + F V+V G +++ A M Sbjct: 68 ALALEKLIQRLGRIDVLVNNAG-AMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQM 126 Query: 400 LDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 + +G G ++ ++S P P + Y+A+KHAL G ++ EL Sbjct: 127 VKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALEL 171
>FABG5_BRANA (Q93X68) 3-oxoacyl-[acyl-carrier-protein] reductase 5, chloroplast| precursor (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase 5) (Fragment) Length = 317 Score = 45.8 bits (107), Expect = 8e-05 Identities = 39/172 (22%), Positives = 79/172 (45%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ +++ G K++++ AR+ +E E V I + + D+S E Sbjct: 82 ASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQI--EEYGGEAITFGGDVSK-EAD 138 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + ++ +A + + ID +++NA R + + +N+ G T+ Sbjct: 139 VDSMMKTAVDKWGT--IDVVVNNAGITRDTL-LIRMKKSQWDEVIDLNLTGVFLCTQAAT 195 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + ++S G + GQA Y+A+K + G+ + E ++ I Sbjct: 196 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNI 247
>SORD_KLEPN (P37079) Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)| (Glucitol-6-phosphate dehydrogenase) (Ketosephosphate reductase) Length = 267 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 9/128 (7%) Frame = +1 Query: 193 SSDEKSLKEVVHSAESLFSS-AGIDYMMHNAAFERPK--------RGALEETEEGLKATF 345 S+D S EV + +++ + ID +++NA P+ G E E + Sbjct: 57 STDISSATEVQQTIDAIIQRWSRIDGLVNNAGVNFPRLLVDEKAPAGRYELNEAAFEKMV 116 Query: 346 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 525 +N G +++ +A M+ + G V +SS +G + GQ+ Y+A+K ALN + S Sbjct: 117 NINQKGVFFMSQAVARQMVKQRAGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSK 176 Query: 526 ELCTKGIK 549 EL GI+ Sbjct: 177 ELGKYGIR 184
>DHB3_MOUSE (P70385) Estradiol 17-beta-dehydrogenase 3 (EC 1.1.1.62)| (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase) Length = 305 Score = 45.4 bits (106), Expect = 1e-04 Identities = 45/175 (25%), Positives = 80/175 (45%), Gaps = 4/175 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDE--K 207 A GIG+ S + A G ++L +R E+L+ + I + S V+++ D + ++ Sbjct: 52 AGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEI-ERTTGSGVKIVQADFTREDIYD 110 Query: 208 SLKEVVHSAES--LFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 +KE + E+ L ++ G+ + F L + E + N+ + +T+ Sbjct: 111 HIKEHLEGLENGILVNNVGMLPSFFPSHF-------LSSSGES-QNLIHCNITSVVKMTQ 162 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 L+ M R G + +SS A P P +LYSASK + + +L E KGI Sbjct: 163 LVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGI 217
>DHG3_BACME (P39484) Glucose 1-dehydrogenase 3 (EC 1.1.1.47) (GLCDH-III)| Length = 261 Score = 45.1 bits (105), Expect = 1e-04 Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 2/173 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 S G+G ++++F AK++++ N EE E + + + ++ D++ +E Sbjct: 16 STGLGRAMAVRFGQEEAKVVINYYNNEE-EALDAKKEVEEAGGQAIIVQGDVTKEE---- 70 Query: 217 EVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +VV+ ++ G +D M++NA E P E + + N+ G +R Sbjct: 71 DVVNLVQTAIKEFGTLDVMINNAGVENPVPSH-ELSLDNWNKVIDTNLTGAFLGSREAIK 129 Query: 394 FMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + ++ + G+ + MSS +P P Y+ASK + +L E KGI+ Sbjct: 130 YFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKQMTETLALEYAPKGIR 182
>DHB7_MOUSE (O88736) 3-keto-steroid reductase (EC 1.1.1.270) (Estradiol| 17-beta-dehydrogenase 7) (EC 1.1.1.62) (17-beta-HSD 7) (17-beta-hydroxysteroid dehydrogenase 7) Length = 334 Score = 44.7 bits (104), Expect = 2e-04 Identities = 52/211 (24%), Positives = 85/211 (40%), Gaps = 40/211 (18%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLG--AKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEK 207 AS GIG L + + L L+ RN + V+ +++ HP ++V ++ MD+S Sbjct: 10 ASSGIGLALCGRLLAEDDDLHLCLACRNLSKARAVRDTLLASHPSAEVSIVQMDVS---- 65 Query: 208 SLKEVVHSAESLFSS-AGIDYMMHNAA----------------FER-------PKRGALE 315 SL+ VV AE + +DY+ NA F R G L Sbjct: 66 SLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFTTAEGILT 125 Query: 316 E----TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVP--------- 456 + T +GL+ F+ N+FG L R L P + ++ +S+ Sbjct: 126 QNDSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKANFSLEDIQ 185 Query: 457 -TPGQALYSASKHALNGYFASLRSELCTKGI 546 + G YS+SK+A + +L KG+ Sbjct: 186 HSKGPEPYSSSKYATDLLNVALNRNFNQKGL 216
>DHI2_HUMAN (P80365) Corticosteroid 11-beta-dehydrogenase isozyme 2 (EC| 1.1.1.-) (11-DH2) (11-beta-hydroxysteroid dehydrogenase type 2) (11-beta-HSD2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) Length = 405 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/128 (26%), Positives = 58/128 (45%) Frame = +1 Query: 166 KVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATF 345 ++ +L MDL+ + V+ ++ +S G+ +++NA A ++ Sbjct: 131 RLRLLQMDLTKPG-DISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCM 189 Query: 346 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 525 +VN FG + LT+ L P +L G V + S AG +P P Y SK A+ + Sbjct: 190 EVNFFGALELTKGLLP-LLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248 Query: 526 ELCTKGIK 549 EL G+K Sbjct: 249 ELLPWGVK 256
>DHGA_BACME (P10528) Glucose 1-dehydrogenase A (EC 1.1.1.47)| Length = 261 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 2/173 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 S G+G ++++F AK++++ N EE E + + + ++ D++ +E Sbjct: 16 STGLGRAMAVRFGQEEAKVVINYYNNEE-EALDAKKEVEEAGGQAIIVQGDVTKEE---- 70 Query: 217 EVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +VV+ ++ G +D M++NA E P E + + N+ G +R Sbjct: 71 DVVNLVQTAIKEFGTLDVMINNAGVENPVPSH-ELSLDNWNKVIDTNLTGAFLGSREAIK 129 Query: 394 FMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + ++ + G+ + MSS +P P Y+ASK + +L E KGI+ Sbjct: 130 YFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
>DHG4_BACME (P39485) Glucose 1-dehydrogenase 4 (EC 1.1.1.47) (GLCDH-IV)| Length = 261 Score = 44.3 bits (103), Expect = 2e-04 Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 2/173 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 S G+G ++++F AK++++ N EE E + + + ++ D++ +E Sbjct: 16 STGLGRAMAVRFGQEEAKVVINYYNNEE-EALDAKKEVEEAGGQAIIVQGDVTKEE---- 70 Query: 217 EVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +VV+ ++ G +D M++NA E P E + + N+ G +R Sbjct: 71 DVVNLVQTAIKEFGTLDVMINNAGVENPVPSH-ELSLDNWNKVIDTNLTGAFLGSREAIK 129 Query: 394 FMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + ++ + G+ + MSS +P P Y+ASK + +L E KGI+ Sbjct: 130 YFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIR 182
>HSD_STREX (P19992) 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase (EC| 1.1.1.53) Length = 255 Score = 44.3 bits (103), Expect = 2e-04 Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 2/173 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 +RG+G + Q + GA+++L+ EE + +D++ +E + Sbjct: 15 ARGLGAEAARQAVAAGARVVLADVLDEEGAATAREL-----GDAARYQHLDVTIEEDWQR 69 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETE--EGLKATFKVNVFGTITLTRLLA 390 V ++ E S +D +++NA G ETE E + +N+ G + + Sbjct: 70 VVAYAREEFGS---VDGLVNNAGIST---GMFLETESVERFRKVVDINLTGVFIGMKTVI 123 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 P M D G G V +SSAAG + + Y ASK + G EL T I+ Sbjct: 124 PAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIR 176
>SPRE_RAT (P18297) Sepiapterin reductase (EC 1.1.1.153) (SPR)| Length = 262 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 16/187 (8%) Frame = +1 Query: 16 LCG*RXASRGIGEVLSMQFASL---GAKLILSARNKEELERVKHNIMSKHPDSKVEVLPM 186 +C ASRG G L+ Q A L G+ L+LSAR+ L ++K + ++ P +V + Sbjct: 10 VCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQPGLQVVLAAA 69 Query: 187 DLSSDEKSLKEVVHSAESLFSSAGID--YMMHNAAFERPKRGALEETEEG---LKATFKV 351 DL + E +++++ + L + +++NA G L + +G + +V Sbjct: 70 DLGT-ESGVQQLLSAVRELPRPERLQRLLLINNA-------GTLGDVSKGFLNINDLAEV 121 Query: 352 NVFGTITLTRLLA-------PFMLDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGY 507 N + + LT +L F G+ VV +SS P G LY A K A + Sbjct: 122 NNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDML 181 Query: 508 FASLRSE 528 + L E Sbjct: 182 YQVLAVE 188
>FABI_AQUAE (O67505) Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9)| (NADH-dependent enoyl-ACP reductase) Length = 270 Score = 43.9 bits (102), Expect = 3e-04 Identities = 42/171 (24%), Positives = 72/171 (42%), Gaps = 3/171 (1%) Frame = +1 Query: 40 RGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKE 219 R I ++ F GA+L + + +RV+ D V+ + L D K+LK+ Sbjct: 18 RSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKC-DVSLDEDIKNLKK 76 Query: 220 VVHSAESLFSSAGIDYMMHNAAF---ERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 + + +D ++H+ A+ E K G ++ + EG K ++V+ I LTR L Sbjct: 77 FLEE-----NWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYSLIALTRELL 131 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKG 543 P M R G V +S + P + +K AL L ++ G Sbjct: 132 PLMEGRN-GAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHG 181
>MTDH_UROFA (O00058) Probable NADP-dependent mannitol dehydrogenase (EC| 1.1.1.138) (MtDH) (Mannitol 2-dehydrogenase [NADP+]) (Planta-induced rust protein 8) Length = 256 Score = 43.9 bits (102), Expect = 3e-04 Identities = 42/181 (23%), Positives = 75/181 (41%), Gaps = 10/181 (5%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEK--- 207 +RGIG +S A GA + + + ++ E I K+ K + D+ K Sbjct: 18 NRGIGLAMSQACADAGAAVGIIYNSAKDAEDRASEISKKY-GVKCKAYQCDVGQQHKVKE 76 Query: 208 ---SLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 + E + L ++AG+ + + AL+ ++ F VNVFG Sbjct: 77 VFKKINEELGPVTGLIANAGVSVV----------KEALQYNKDDFNKIFDVNVFGVFNCA 126 Query: 379 RLLAPFMLDRGM--GHFVVMSSAAGKVPTP--GQALYSASKHALNGYFASLRSELCTKGI 546 + +A D G G V++SS + ++ Q Y++SK A++ L +E K I Sbjct: 127 QAMAQIWTDTGFQRGSVVIISSMSSQICNRPLTQCFYNSSKAAVSNLGKCLAAEWAEKSI 186 Query: 547 K 549 + Sbjct: 187 R 187
>DHKR_STRCM (P41177) Monensin polyketide synthase putative ketoacyl reductase| (EC 1.3.1.-) (ORF5) Length = 261 Score = 43.9 bits (102), Expect = 3e-04 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 3/174 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG + A+ G + L AR + ++ + + +++ +VL + D S+ Sbjct: 14 ATSGIGLATARLLAAQGHLVFLGARTESDVIATVKALRNDGLEAEGQVLDV---RDGASV 70 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTITLTR--L 384 V +A + ID +++NA R G + T+E N+ +TR L Sbjct: 71 TAFVQAAVDRYGR--IDVLVNNAG--RSGGGVTADLTDELWDDVIDTNLNSVFRMTRAVL 126 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M R G + ++S AGK A YSASKH + G+ +L +EL GI Sbjct: 127 TTGGMRTRERGRIINVASTAGKQGVVLGAPYSASKHGVVGFTKALGNELAPTGI 180
>FABG_CHLTR (P38004) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 247 Score = 43.9 bits (102), Expect = 3e-04 Identities = 41/171 (23%), Positives = 76/171 (44%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 SRGIG ++ FA GA + + N E + + S+ +V +D+S ++ Sbjct: 15 SRGIGFSIAKLFAEQGANVQIWGINGEAGQAAAQTL-SEQTGRQVSFALVDVSKNDMVSA 73 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 +V + L ID +++NA R + +EE + N+ + + Sbjct: 74 QVQNF---LAEYNTIDVIVNNAGITRDAL-LMRMSEEEWSSVINTNLGSIYNVCSAVIRP 129 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M+ G + +SS G +PGQ Y+A+K + G+ +L E+ +K I+ Sbjct: 130 MIKARSGAIINISSIVGLRGSPGQTNYAAAKAGIIGFSKALSKEVGSKNIR 180
>BDHA_RALEU (Q9X6U2) D-beta-hydroxybutyrate dehydrogenase (EC 1.1.1.30) (BDH)| (3-hydroxybutyrate dehydrogenase) (3-HBDH) Length = 258 Score = 43.9 bits (102), Expect = 3e-04 Identities = 40/172 (23%), Positives = 78/172 (45%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ++ GIG ++ A+ GA +I++ + + K I +V D+S + + Sbjct: 12 STSGIGLGIAKALAAQGANIIVNGFG--DADAAKAEIAQAGQGIRVGYHGADMSKAAE-I 68 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTITLTRLLA 390 ++++ A+S F G D +++NA + A+E+ E A +N+ TRL Sbjct: 69 EDMMRYAQSDFG--GADILVNNAGIQHV--AAIEDFPPERWDAIIAINLTSAFHTTRLAL 124 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 P M + G + ++S G V + ++ Y A+KH + G+ E G+ Sbjct: 125 PGMKQKDWGRIINVASTHGLVASAQKSAYVAAKHGIVGFTKVTALETAQTGV 176
>FABG_ARATH (P33207) 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast| precursor (EC 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase) Length = 319 Score = 43.5 bits (101), Expect = 4e-04 Identities = 38/173 (21%), Positives = 73/173 (42%), Gaps = 2/173 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ +++ G K++++ AR+ +E E V I + + D Sbjct: 84 ASRGIGKAIALALGKAGCKVLVNYARSAKEAEEVAKQIEEYGGQA------ITFGGDVSK 137 Query: 211 LKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +V ++ G ID +++NA R + + +N+ G T+ Sbjct: 138 ATDVDAMMKTALDKWGTIDVVVNNAGITRDTL-LIRMKQSQWDEVIALNLTGVFLCTQAA 196 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + +SS G + GQA Y+A+K + + + E ++ I Sbjct: 197 VKIMMKKKRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNI 249
>FABG4_BRANA (Q949M2) 3-oxoacyl-[acyl-carrier-protein] reductase 4 (EC| 1.1.1.100) (3-ketoacyl-acyl carrier protein reductase 4) (Fragment) Length = 254 Score = 43.5 bits (101), Expect = 4e-04 Identities = 40/175 (22%), Positives = 82/175 (46%), Gaps = 4/175 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 ASRGIG+ +++ G K++++ AR+ +E E V I + + D+S E Sbjct: 22 ASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQI--EEYGGQAITFGGDVSK-EAD 78 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAA---FERPKRGALEETEEGLKATFKVNVFGTITLTR 381 + ++ +A + + ID +++NA R K+ +E + +N+ G ++ Sbjct: 79 VDAMMKTAVDKWGT--IDVVVNNAGDTLLIRMKKSQWDEVMD-------LNLTGVFLCSQ 129 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + ++S G + GQA Y+A+K + G+ + E ++ I Sbjct: 130 AATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNI 184
>DER_CHICK (Q8JIS3) D-erythrulose reductase (EC 1.1.1.162)| Length = 246 Score = 43.1 bits (100), Expect = 5e-04 Identities = 38/157 (24%), Positives = 79/157 (50%), Gaps = 1/157 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A +GIG +++ GA++ +R +LE +++ + P +E L +DL+ + Sbjct: 17 AGKGIGRAVAVALCKAGARVTALSRTAADLE----SLVRECPG--IEPLCLDLADWD--- 67 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + E+ +AG ++ N A + L+ T E ++ +F VN + +++++A Sbjct: 68 -----ATEAAVGAAGPFELLVNNAAVAMLQPFLQVTREAVERSFDVNFRAVLHVSQIVAR 122 Query: 394 FMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALN 501 M+ +G+ G V +SS A + A+Y ++K AL+ Sbjct: 123 QMIAQGLPGAIVNVSSQASQRALRDHAVYCSTKSALD 159
>FABG_BUCBP (Q89AG9) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 245 Score = 43.1 bits (100), Expect = 5e-04 Identities = 35/172 (20%), Positives = 81/172 (47%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+RG+G+ ++ + ++ ++ ++ I++K+ + + +D+++ Sbjct: 13 ANRGLGKGIAEELSNTNNITVIGTSTSQK----GCKIINKYLKNNGIGIKLDITNPN--- 65 Query: 214 KEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 E+ + + ++ + G +D +++NA R K +T++ + VN+ +++ + Sbjct: 66 -EITKTMDFVYKNFGRVDILINNAGIIRDKLLINMKTQDW-NSVLNVNLNSIFYMSKSVI 123 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ G + + S + GQ YSA+K L G+ SL EL KGI Sbjct: 124 RNMIKNKQGKIITIGSVIAHIGNCGQTNYSAAKLGLVGFHKSLALELAPKGI 175
>DHG2_BACSU (P80869) Glucose 1-dehydrogenase 2 (EC 1.1.1.47) (GLCDH-II)| (GDH-II) (General stress protein 74) (GSP74) Length = 258 Score = 43.1 bits (100), Expect = 5e-04 Identities = 41/178 (23%), Positives = 80/178 (44%), Gaps = 6/178 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNK-----EELERVKHNIMSKHPDSKVEVLPMDLSS 198 +S+GIG+ ++ +F ++++ + E LE +K N K + D+S Sbjct: 15 SSKGIGKAIAERFGKEKMNVVVNYHSDPSGADETLEIIKQN------GGKAVSVEADVSK 68 Query: 199 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 +E ++ ++ +A F + +D M++N+ F + E + E + VNV GT Sbjct: 69 EE-GIQALLDTALEHFGT--LDVMVNNSGFNGVEAMPHEMSLEDWQRVIDVNVTGTFLGA 125 Query: 379 RLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + M+ + G+ + +SS ++P P YS SK + +L KGI+ Sbjct: 126 KAALNHMMKNNIKGNVLNISSVHQQIPRPVNVQYSTSKGGIKMMTETLALNYADKGIR 183
>TS2_MAIZE (P50160) Sex determination protein tasselseed-2| Length = 336 Score = 42.7 bits (99), Expect = 7e-04 Identities = 42/177 (23%), Positives = 74/177 (41%), Gaps = 6/177 (3%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 +RGIGE + FA GA+++++ +++ ++ +V + D+S ++ Sbjct: 64 ARGIGEAIVRLFAKHGARVVIA-----DIDDAAGEALASALGPQVSFVRCDVSVED---- 114 Query: 217 EVVHSAESLFSSAG--IDYMMHNAAF----ERPKRGALEETEEGLKATFKVNVFGTITLT 378 +V + + S G +D +NA R R L +VN G Sbjct: 115 DVRRAVDWALSRHGGRLDVYCNNAGVLGRQTRAARSILSFDAAEFDRVLRVNALGAALGM 174 Query: 379 RLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + A M R G V ++S A + G Y+ASKHA+ G + EL G++ Sbjct: 175 KHAARAMAPRRAGSIVSVASVAAVLGGLGPHAYTASKHAIVGLTKNAACELRAHGVR 231
>RDH7_RAT (P55006) Retinol dehydrogenase 7 (EC 1.1.1.105) (Retinol| dehydrogenase type III) (RODH III) Length = 317 Score = 42.4 bits (98), Expect = 9e-04 Identities = 38/169 (22%), Positives = 79/169 (46%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G G +L+ Q G +++ + ++ E+++ SK D ++E + +D++ E S+ Sbjct: 40 GFGNLLARQLDRRGMRVLAACLTEKGAEQLR----SKTSD-RLETVILDVTKTE-SIVAA 93 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 + + G+ +++NA P ++ + VN+ G I +T + P ++ Sbjct: 94 TQWVKERVGNRGLWGLVNNAGISVPMGPNEWMRKKDFASVLDVNLLGVIEVTLNMLP-LV 152 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G V ++S G++ G Y SK+ + + SLR EL G+K Sbjct: 153 RKARGRVVNIASTMGRMSLLGGG-YCISKYGVEAFSDSLRRELTYFGVK 200
>RDH3_RAT (P50169) Retinol dehydrogenase 3 (EC 1.1.1.105) (Retinol| dehydrogenase type I) (RODH I) Length = 317 Score = 42.4 bits (98), Expect = 9e-04 Identities = 38/169 (22%), Positives = 79/169 (46%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G G +L+ Q G +++ + ++ E+++ SK D ++E + +D++ E S+ Sbjct: 40 GFGNLLARQLDRRGMRVLAACLTEKGAEQLR----SKTSD-RLETVILDVTKTE-SIVAA 93 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 + + G+ +++NA P ++ + VN+ G I +T + P ++ Sbjct: 94 TQWVKERVGNRGLWGLVNNAGISVPVGPNEWMRKKDFASVLDVNLLGVIEVTLNMLP-LV 152 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G V ++S G++ G Y SK+ + + SLR EL G+K Sbjct: 153 RKARGRVVNIASTMGRMSLVGGG-YCISKYGVEAFSDSLRRELTYFGVK 200
>ENTA_ECOLI (P15047) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC| 1.3.1.28) Length = 248 Score = 42.4 bits (98), Expect = 9e-04 Identities = 45/175 (25%), Positives = 74/175 (42%), Gaps = 3/175 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLI-LSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 A +GIG ++ F GAK+ +E +M ++V + L ++ + Sbjct: 13 AGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETER 72 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTITL-TRL 384 L +V++A L + GA ++ ++E + TF VNV G L + Sbjct: 73 LDALVNAAGIL------------------RMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + F RG G V ++S A P G + Y ASK AL S+ EL G++ Sbjct: 115 MNQFRRQRG-GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168
>BAIA2_EUBSP (P19337) Bile acid 7-dehydroxylase 2 (EC 1.17.1.6) (Cholate| 7-alpha-dehydroxylase 2) (Bile acid-inducible protein 2) Length = 249 Score = 42.4 bits (98), Expect = 9e-04 Identities = 41/171 (23%), Positives = 68/171 (39%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 +RGIG + F GAK+ + +EE++ + +P+ +V DL+S + + Sbjct: 15 TRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAPDLTSRDAVMA 74 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 V A+ +D M++NA +EE K +NV G Sbjct: 75 AVGQVAQKY---GRLDVMINNAGI-TSNNVFSRVSEEEFKHIMDINVTGVFNGAWCAYQC 130 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M D G + +S G + Y ASK ++ G L E+ K I+ Sbjct: 131 MKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIR 181
>DHSO_RHOSH (Q59787) Sorbitol dehydrogenase (EC 1.1.1.14) (L-iditol| 2-dehydrogenase) (Polyol dehydrogenase) Length = 256 Score = 42.0 bits (97), Expect = 0.001 Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 1/172 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ++RGIG + + GA++ ++ N LE + P + L + +D+ S+ Sbjct: 13 SARGIGRAFAEAYVREGARVAIADIN---LEAARATAAEIGPAACAIALDV---TDQASI 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 V AE L ID +++NAA +E T E F +NV GT+ + + +A Sbjct: 67 DRCV--AELLDRWGSIDILVNNAALF-DLAPIVEITRESYDRLFAINVSGTLFMMQAVAR 123 Query: 394 FMLDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ G G ++ M+S AG+ +Y A+K A+ S L GI Sbjct: 124 AMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGI 175
>DHB7_RAT (Q62904) 3-keto-steroid reductase (EC 1.1.1.270) (Estradiol| 17-beta-dehydrogenase 7) (EC 1.1.1.62) (17-beta-HSD 7) (17-beta-hydroxysteroid dehydrogenase 7) (PRL receptor-associated protein) (PRAP) Length = 334 Score = 42.0 bits (97), Expect = 0.001 Identities = 51/211 (24%), Positives = 85/211 (40%), Gaps = 40/211 (18%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLG--AKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEK 207 AS GIG L + + L L+ RN + V+ +++ HP ++V ++ MD+S Sbjct: 10 ASSGIGLALCGRLLAEDDDLHLCLACRNLSKAGAVRDALLASHPSAEVSIVQMDVS---- 65 Query: 208 SLKEVVHSAESLFSS-AGIDYMMHNAA----------------FER-------PKRGALE 315 +L+ VV AE + +DY+ NA F R G L Sbjct: 66 NLQSVVRGAEEVKRRFQRLDYLYLNAGIMPNPQLNLKAFFCGIFSRNVIHMFSTAEGLLT 125 Query: 316 E----TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPT-------- 459 + T +G + F+ N+FG L R L P + ++ +S+ + Sbjct: 126 QNDKITADGFQEVFETNLFGHFILIRELEPLLCHSDNPSQLIWTSSRNAKKSNFSLEDIQ 185 Query: 460 --PGQALYSASKHALNGYFASLRSELCTKGI 546 GQ YS+SK+A + +L KG+ Sbjct: 186 HAKGQEPYSSSKYATDLLNVALNRNFNQKGL 216
>FABG_VIBHA (P55336) 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100)| (3-ketoacyl-acyl carrier protein reductase) Length = 244 Score = 42.0 bits (97), Expect = 0.001 Identities = 35/171 (20%), Positives = 72/171 (42%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 ASRGIG ++ GA +I +A ++ + + + V D+ S E +L Sbjct: 13 ASRGIGRAIAELLVERGATVIGTATSEGGAAAISEYLGENGKGLALNV--TDVESIEATL 70 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 K + ID +++NA R + ++ N+ +++ + Sbjct: 71 KTINDEC------GAIDILVNNAGITRDNL-LMRMKDDEWNDIINTNLTPIYRMSKAVLR 123 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M+ + G + + S G + GQ Y+A+K + G+ S+ E+ ++G+ Sbjct: 124 GMMKKRAGRIINVGSVVGTMGNAGQTNYAAAKAGVIGFTKSMAREVASRGV 174
>RDH2_RAT (P50170) Retinol dehydrogenase 2 (EC 1.1.1.105) (Retinol| dehydrogenase type II) (RODH II) (29 k-protein) Length = 317 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/169 (22%), Positives = 79/169 (46%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G G +L+ Q G +++ + ++ E+++ SK D ++E + +D++ E S+ Sbjct: 40 GFGNLLARQLDRRGMRVLAACLTEKGAEQLR----SKTSD-RLETVILDVTKTE-SIVAA 93 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFML 402 + + G+ +++NA ++ + + VN+ G I +T P ++ Sbjct: 94 TQWVKERVGNTGLWGLVNNAGISGHLGPNEWMNKQNIASVLDVNLLGMIEVTLSTVP-LV 152 Query: 403 DRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + G V ++S AG++ G Y SK+ + + SLR EL G+K Sbjct: 153 RKARGRVVNVASIAGRLSFCGGG-YCISKYGVEAFSDSLRRELSYFGVK 200
>DHB4_HUMAN (P51659) Peroxisomal multifunctional enzyme type 2 (MFE-2)| (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.107) (3-alpha,7-alpha,12-alpha-trihydroxy-5 Length = 735 Score = 41.2 bits (95), Expect = 0.002 Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 1/177 (0%) Frame = +1 Query: 1 RHEARLCG*RXASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVL 180 R + R+ A G+G ++ FA GA ++++ + K ++ + ++ Sbjct: 5 RFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRR 64 Query: 181 PMDLSSDEKSLKEVVHSAESLFSSAG-IDYMMHNAAFERPKRGALEETEEGLKATFKVNV 357 ++ S++E ++ + G ID +++NA R + A ++E +V++ Sbjct: 65 GGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFA-RISDEDWDIIHRVHL 123 Query: 358 FGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 G+ +TR M + G ++ SSA+G GQA YSA+K L G SL E Sbjct: 124 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 180
>HCAB_ECOLI (P77646) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase| (EC 1.3.1.-) Length = 270 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/76 (35%), Positives = 33/76 (43%) Frame = +1 Query: 313 EETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKH 492 E E G F VNV G + + AP ++ G + S A P G LY+ASKH Sbjct: 103 ETLETGFHELFNVNVLGYLLGAKACAPALI-ASEGSMIFTLSNAAWYPGGGGPLYTASKH 161 Query: 493 ALNGYFASLRSELCTK 540 A G L EL K Sbjct: 162 AATGLIRQLAYELAPK 177
>YAY8_SCHPO (Q10216) Hypothetical oxidoreductase C4H3.08 in chromosome I (EC| 1.-.-.-) Length = 286 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/171 (21%), Positives = 76/171 (44%), Gaps = 2/171 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSA--RNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 GIG+ ++ FA G+ L++S +++ E + I + + + +D S + + L Sbjct: 53 GIGKAAAVMFAREGSDLVISCLPEERDDAEVTRDLIEREGRNCWIWEGKLDKSDNCRDLV 112 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 + +L ID +++N A+++ + + +E TFK N+F +T+ Sbjct: 113 DF-----ALKKLGWIDVLVNNIAYQQVAQSIEDIDDEQWDLTFKTNIFSFFWVTKAAISH 167 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M + V SS V P Y+++K A+ + L ++ GI+ Sbjct: 168 M--KSGSSIVNCSSINAYVGRPDLLDYTSTKGAITAFTRGLSNQYAQHGIR 216
>Y4MP_RHISN (P55575) Putative short-chain type dehydrogenase/reductase y4mP (EC| 1.-.-.-) Length = 253 Score = 40.8 bits (94), Expect = 0.003 Identities = 38/175 (21%), Positives = 77/175 (44%), Gaps = 3/175 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 + RGIG + FAS GA++ + N +E + ++ + + L D Sbjct: 15 SKRGIGRATAELFASHGARVAILDINADEAKAAAGDLPPVEHGAHI-----GLRCDVADR 69 Query: 214 KEVVHSAESLFSSAGI-DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLA 390 +++ + S+ G+ + +++NA +P + L+ ++ + VN+ G + L+++ Sbjct: 70 ASCTSASDEVLSAFGVANILINNAGITQPVK-TLDISDADWQRIVAVNMTGVLNLSQVFI 128 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTP--GQALYSASKHALNGYFASLRSELCTKGIK 549 P M G G MSS + + G YSA+K + G ++ E I+ Sbjct: 129 PNMRQNGGGSIACMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMAREFGPDSIR 183
>VER1_ASPPA (P50161) Versicolorin reductase (EC 1.1.-.-) (VER-1)| Length = 262 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/161 (27%), Positives = 74/161 (45%), Gaps = 3/161 (1%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKS 210 A RGIG +++ GAK++++ A ++E E+V I + D+ + D+ E + Sbjct: 17 AGRGIGAAIAVALGERGAKVVVNYAHSREAAEKVVEQIKANGTDA--IAIQADVGDPEAT 74 Query: 211 LKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTITLTRLL 387 K + AE++ +D + NA G L++ T E F+VN G + R Sbjct: 75 AKLM---AETVRHFGYLDIVSSNAGI--VSFGHLKDVTPEEFDRVFRVNTRGQFFVAREA 129 Query: 388 APFMLDRGMGHFVVMSSAAGKVP-TPGQALYSASKHALNGY 507 M R G ++ SS V P A+YS SK A++ + Sbjct: 130 YRHM--REGGRIILTSSNTACVKGVPKHAVYSGSKGAIDTF 168
>RDH14_MOUSE (Q9ERI6) Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol| dehydrogenase PAN2) Length = 334 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 12/147 (8%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSK----------HPDSKVEVLP 183 A+ G+G + + LGA++I+ R++ E + + D ++ V Sbjct: 52 ANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTDGQLVVKE 111 Query: 184 MDLSSDEKSLKEV-VHSAESLFSSAGIDYMMHNA-AFERPKRGALEETEEGLKATFKVNV 357 +DL+ SL+ V E L +D +++NA F P +TE+G + F VN Sbjct: 112 LDLA----SLRSVRAFCQELLQEEPRLDVLINNAGVFHCP----YTKTEDGFEMQFGVNH 163 Query: 358 FGTITLTRLLAPFMLDRGMGHFVVMSS 438 G LT LL + VV+SS Sbjct: 164 LGHFLLTNLLLGLLKSSAPSRIVVVSS 190
>25KD_SARPE (P23170) Development-specific 25 kDa protein| Length = 258 Score = 40.4 bits (93), Expect = 0.003 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Frame = +1 Query: 322 EEGLKATFKVNVFGTITLTRLLAPFMLDRGMGH---FVVMSSAAGKVPTPGQALYSASKH 492 ++ ++ T VN+ G I T + P+M GH V +SS G P P ++YSA+KH Sbjct: 97 DKDVETTVAVNLTGLINTTLMFMPYMDKTQSGHGGMVVSISSVYGLEPGPAFSVYSAAKH 156 Query: 493 ALNGYFASLRSE 528 G+ S+ E Sbjct: 157 GGIGFTRSMADE 168
>RDH11_HUMAN (Q8TC12) Retinol dehydrogenase 11 (EC 1.1.1.-) (Retinal reductase| 1) (RalR1) (Prostate short-chain dehydrogenase/reductase 1) (Androgen-regulated short-chain dehydrogenase/reductase 1) (HCV core-binding protein HCBP12) Length = 318 Score = 40.0 bits (92), Expect = 0.004 Identities = 37/137 (27%), Positives = 63/137 (45%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ + + A GA++ L+ R+ E+ E V I + + +V V +DL SD KS+ Sbjct: 49 ANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL-SDTKSI 107 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + + L + +++NA +T +G + VN G LT LL Sbjct: 108 R--AFAKGFLAEEKHLHVLINNAGV---MMCPYSKTADGFEMHIGVNHLGHFLLTHLLLE 162 Query: 394 FMLDRGMGHFVVMSSAA 444 + + V +SS A Sbjct: 163 KLKESAPSRIVNVSSLA 179
>DHB8_HUMAN (Q92506) Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62)| (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6) Length = 261 Score = 40.0 bits (92), Expect = 0.004 Identities = 45/178 (25%), Positives = 76/178 (42%), Gaps = 6/178 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLI---LSARNKEELERVKHNIMSKH--PDSKVEVLPMDLSS 198 A GIG +S++ A GA + L +E R+ SK P D+S Sbjct: 19 AGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVS- 77 Query: 199 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 + ++ + ++ ++ FS ++ + A L +E+ VN+ GT +T Sbjct: 78 EARAARCLLEQVQACFSRP--PSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVT 135 Query: 379 RLLAPFMLDRGM-GHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + A ++ G G + +SS GKV GQ Y+ASK + G + EL GI+ Sbjct: 136 QAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193
>YMEC_METEX (Q49117) Hypothetical oxidoreductase in meaA 3'region (EC 1.-.-.-)| (ORFC) (Fragment) Length = 153 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Frame = +1 Query: 307 ALEE-TEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSA 483 A+EE TEE + F VNV G + T+ + + + G + +SS V P A+YS Sbjct: 4 AIEEVTEEHYRRIFDVNVLGVLLATQAASKHLGEGGS--IINISSVVTDVLMPTSAVYSG 61 Query: 484 SKHALNGYFASLRSELCTKGIK 549 +K ALN L +EL + I+ Sbjct: 62 TKGALNAISGVLANELAPRKIR 83
>YURA_MYXXA (P25970) Hypothetical oxidoreductase in uraA 5'region (EC 1.-.-.-)| (Fragment) Length = 258 Score = 39.7 bits (91), Expect = 0.006 Identities = 26/75 (34%), Positives = 37/75 (49%) Frame = +1 Query: 325 EGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNG 504 E ++ NV G + P M++R GH V +SS AG P YSASK L+ Sbjct: 111 ERVRGIIDTNVTGAAATLSAVLPQMVERKRGHLVGVSSLAGFRGLPATR-YSASKAFLST 169 Query: 505 YFASLRSELCTKGIK 549 + SLR +L G++ Sbjct: 170 FMESLRVDLRGTGVR 184
>BAIA1_EUBSP (P07914) Bile acid 7-dehydroxylase 1/3 (EC 1.17.1.6) (Cholate| 7-alpha-dehydroxylase 1/3) (Bile acid-inducible protein 1/3) Length = 249 Score = 39.7 bits (91), Expect = 0.006 Identities = 40/171 (23%), Positives = 67/171 (39%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 +RGIG + F GAK+ + +EE++ + +P+ +V DL+S + + Sbjct: 15 TRGIGFAAAKLFIENGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAPDLTSRDAVMA 74 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPF 396 V A+ +D M++NA + +EE K +NV G Sbjct: 75 AVGTVAQKY---GRLDVMINNAGITMNSVFS-RVSEEDFKNIMDINVNGVFNGAWSAYQC 130 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 M D G + +S G + Y SK + G L E+ K I+ Sbjct: 131 MKDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGREIIRKNIR 181
>Y3820_MYCBO (P66784) Putative oxidoreductase Mb3820 (EC 1.-.-.-)| Length = 254 Score = 39.3 bits (90), Expect = 0.007 Identities = 20/68 (29%), Positives = 36/68 (52%) Frame = +1 Query: 346 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 525 ++N +++ LLA M +G G + MSSAAG+ +Y ++K L+G++ L Sbjct: 117 EINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSE 176 Query: 526 ELCTKGIK 549 L G++ Sbjct: 177 ALREYGVR 184
>Y3791_MYCTU (P66783) Putative oxidoreductase Rv3791/MT3899 (EC 1.-.-.-)| Length = 254 Score = 39.3 bits (90), Expect = 0.007 Identities = 20/68 (29%), Positives = 36/68 (52%) Frame = +1 Query: 346 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRS 525 ++N +++ LLA M +G G + MSSAAG+ +Y ++K L+G++ L Sbjct: 117 EINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSE 176 Query: 526 ELCTKGIK 549 L G++ Sbjct: 177 ALREYGVR 184
>HCDS_XANP2 (Q56841) 2-(S)-hydroxypropyl-CoM dehydrogenase (EC 1.1.1.269)| (S-HPCDH) (Aliphatic epoxide carboxylation component IV) Length = 249 Score = 39.3 bits (90), Expect = 0.007 Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 1/83 (1%) Frame = +1 Query: 304 GALEETE-EGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYS 480 G++ TE E VNV GT ++ ML+RG G V S AG V P A Y Sbjct: 92 GSVHATEVETWSRIMAVNVTGTFLASKAALFGMLERGRGAIVNFGSVAGLVGIPTMAAYC 151 Query: 481 ASKHALNGYFASLRSELCTKGIK 549 A+K A+ + ++ +GI+ Sbjct: 152 AAKGAVVNLTRQMAADYSGRGIR 174
>FOX2_NEUCR (Q01373) Peroxisomal hydratase-dehydrogenase-epimerase (HDE)| (Multifunctional beta-oxidation protein) (MFP) [Includes: 2-enoyl-CoA hydratase (EC 4.2.1.-); D-3-hydroxyacyl CoA dehydrogenase (EC 1.1.1.-)] Length = 894 Score = 39.3 bits (90), Expect = 0.007 Identities = 41/164 (25%), Positives = 71/164 (43%), Gaps = 2/164 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSAR-NKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKE 219 GIG + FA GA ++++ N +++ + K +K D Sbjct: 325 GIGRAYCLAFARAGASVVVNDLVNPDDVVNEIKKMGGKAVGAKFSAEDGDA--------- 375 Query: 220 VVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL-KATFKVNVFGTITLTRLLAPF 396 VV +A F +D +++NA R K A ++ L V+ GT +T+ P+ Sbjct: 376 VVKAAIDAFGR--VDIVVNNAGILRDK--AFHNMDDSLWDPVMNVHARGTYKVTKAAWPY 431 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 L + G + +S +G GQA YSA+K A+ G+ ++ E Sbjct: 432 FLKQKYGRVLNTTSTSGIYGNFGQANYSAAKCAILGFSRAIALE 475 Score = 38.5 bits (88), Expect = 0.013 Identities = 28/90 (31%), Positives = 42/90 (46%) Frame = +1 Query: 259 IDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSS 438 ID +++NA R +E FKV+V G+ R P+ + G + +S Sbjct: 93 IDILINNAGILRDI-SFKNMKDEDWDLIFKVHVKGSYKTARAAWPYFRKQKFGRVINTAS 151 Query: 439 AAGKVPTPGQALYSASKHALNGYFASLRSE 528 AAG GQA YSA+K + G+ +L E Sbjct: 152 AAGLFGNFGQANYSAAKLGMVGFTETLAKE 181
>BPHB_RHOGO (P47230) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 280 Score = 39.3 bits (90), Expect = 0.007 Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 7/170 (4%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLP--MDLSSDEKSLK 216 G+G + +F GA++ + R+ LE ++ + H D+ V V L S ++++ Sbjct: 16 GLGRAIVDRFVCEGARVAVLDRSVAGLEELR----AAHGDAVVAVEGDVRYLDSHKETVA 71 Query: 217 EVVHSAESL---FSSAGI-DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT-LTR 381 + V + L +AG+ DY A E P+ + +E + +NV G + + Sbjct: 72 KCVETFGKLDCYIGNAGVWDYS--TALVEIPE----DRLDEAFDEMYSINVKGYLLGVKA 125 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 L RG F V S AG P G ALY+ +KHA+ G L EL Sbjct: 126 ALGALYASRGSVIFTV--SNAGFYPAGGGALYTGAKHAIVGMVKQLAYEL 173
>BPHB_PSES1 (P50206) Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC| 1.3.1.56) (Biphenyl-2,3-dihydro-2,3-diol dehydrogenase) (2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase) (Biphenyl-cis-diol dehydrogenase) (2,3-dihydroxy-4-phenylhexa-4,6-diene dehyd Length = 276 Score = 39.3 bits (90), Expect = 0.007 Identities = 42/169 (24%), Positives = 74/169 (43%), Gaps = 6/169 (3%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVK--HNIMSKHPDSKVEVLPMDLSSDEKSLK 216 G+G + +F + GA++ + ++ L+ ++ H + V VL + +K+ + Sbjct: 16 GLGRAIVDRFVAEGARVAVLDKSAARLQELQAAHGAKVLGIEGDVRVL----ADHQKAAR 71 Query: 217 EVVHS---AESLFSSAGI-DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRL 384 E V + + L +AGI DY M + P + + F +NV G + + Sbjct: 72 ECVAAFGKIDCLIPNAGIWDYSM--PLVDIPD----DRIDAAFDEVFHINVKGYLLAVKA 125 Query: 385 LAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P ++ + G V S AG P G LY+ +KHA+ G L EL Sbjct: 126 CLPALV-QSRGSVVFTISNAGFYPNGGGPLYTGAKHAVVGMVRELAYEL 173
>BACC2_BACSU (Q8KWT4) Bacilysin biosynthesis oxidoreductase bacC (EC 1.-.-.-)| Length = 253 Score = 39.3 bits (90), Expect = 0.007 Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 1/150 (0%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 GIG F + A ++++ ++ + E + + K + ++ + D++ DE + + Sbjct: 16 GIGYAAVQAFLNQQANVVVADIDEAQGEAM----IRKENNDRLHFVHTDIT-DEPACQNA 70 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEETE-EGLKATFKVNVFGTITLTRLLAPFM 399 + SA F G+D +++NA E + E E VN+ G +++ +M Sbjct: 71 IRSAVDKFG--GLDVLINNAGIEIV--APIHEMELSNWNKVLNVNLTGMFLMSKHALKYM 126 Query: 400 LDRGMGHFVVMSSAAGKVPTPGQALYSASK 489 L G G+ + S G V P Y+ASK Sbjct: 127 LKSGKGNIINTCSVGGVVAWPDIPAYNASK 156
>DHB8_MOUSE (P50171) Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62)| (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6) Length = 260 Score = 38.9 bits (89), Expect = 0.010 Identities = 45/178 (25%), Positives = 78/178 (43%), Gaps = 6/178 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLI---LSARNKEELERVKHNIMSKH--PDSKVEVLPMDLSS 198 A GIG +S++ A+ GA + L ++ R+ + S+ P K D+S Sbjct: 18 AGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAPRGKHAAFQADVSQ 77 Query: 199 DEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLT 378 + + ++ ++ FS ++ A R + L +EE VN+ GT +T Sbjct: 78 GPAA-RRLLEEVQACFSRPP-SVVVSCAGITRDEF-LLHMSEEDWDRVIAVNLKGTFLVT 134 Query: 379 RLLAPFMLDRG-MGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 + A ++ G G + +SS GKV GQ Y++SK + G + EL GI+ Sbjct: 135 QAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIR 192
>NAHB_PSEU8 (P0A170) 1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase (EC| 1.3.1.60) (Cis-naphthalene dihydrodiol dehydrogenase) Length = 259 Score = 38.9 bits (89), Expect = 0.010 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 7/173 (4%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL---SSDE 204 A GIG L F S G + RN+E+ ++ K +E++ D+ +++E Sbjct: 12 AGSGIGLELVRSFKSAGYYVSALVRNEEQ-----EALLCKEFKDALEIVVGDVRDHATNE 66 Query: 205 KSLKEVVHS---AESLFSSAGI-DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 372 K +K+ + + ++AGI DYM+ + E P E+ F +NV + Sbjct: 67 KLIKQTIDRFGHLDCFIANAGIWDYML---SIEEP----WEKISSSFDEIFDINVKSYFS 119 Query: 373 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P L + G V+ +S + G + Y ASKHA+ G +L EL Sbjct: 120 GISAALP-ELKKTNGSVVMTASVSSHAVGGGGSCYIASKHAVLGMVKALAYEL 171
>NAHB_PSEPU (P0A169) 1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase (EC| 1.3.1.60) (Cis-naphthalene dihydrodiol dehydrogenase) Length = 259 Score = 38.9 bits (89), Expect = 0.010 Identities = 45/173 (26%), Positives = 75/173 (43%), Gaps = 7/173 (4%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL---SSDE 204 A GIG L F S G + RN+E+ ++ K +E++ D+ +++E Sbjct: 12 AGSGIGLELVRSFKSAGYYVSALVRNEEQ-----EALLCKEFKDALEIVVGDVRDHATNE 66 Query: 205 KSLKEVVHS---AESLFSSAGI-DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT 372 K +K+ + + ++AGI DYM+ + E P E+ F +NV + Sbjct: 67 KLIKQTIDRFGHLDCFIANAGIWDYML---SIEEP----WEKISSSFDEIFDINVKSYFS 119 Query: 373 LTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSEL 531 P L + G V+ +S + G + Y ASKHA+ G +L EL Sbjct: 120 GISAALP-ELKKTNGSVVMTASVSSHAVGGGGSCYIASKHAVLGMVKALAYEL 171
>RDH12_MOUSE (Q8BYK4) Retinol dehydrogenase 12 (EC 1.1.1.-)| Length = 316 Score = 38.9 bits (89), Expect = 0.010 Identities = 36/137 (26%), Positives = 63/137 (45%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ + + A GA++ ++ R+ + E I + +S+V V +DL SD KS+ Sbjct: 47 ANTGIGKETARELARRGARVYIACRDVLKGESAASEIRADTKNSQVLVRKLDL-SDTKSI 105 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + + L + +++NA +T +G + F VN G LT LL Sbjct: 106 R--AFAERFLAEEKKLHILINNAGV---MMCPYSKTTDGFETHFGVNHLGHFLLTYLLLE 160 Query: 394 FMLDRGMGHFVVMSSAA 444 + + V +SS A Sbjct: 161 RLKESAPARVVNLSSIA 177
>NOG4_RHIME (P06235) Nodulation protein G (Host-specificity of nodulation| protein C) Length = 244 Score = 38.9 bits (89), Expect = 0.010 Identities = 21/59 (35%), Positives = 31/59 (52%) Frame = +1 Query: 346 KVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLR 522 +VN+ LTR + M+ R G + ++S AG + PGQ Y ASK + G+ S R Sbjct: 109 EVNLTAMFRLTREITQQMIRRRNGRIINVTSVAGAIGNPGQTNYCASKAGMIGFSKSWR 167
>WWOX_DROME (Q9VLU5) WW domain-containing oxidoreductase (EC 1.1.1.-)| Length = 409 Score = 38.5 bits (88), Expect = 0.013 Identities = 36/119 (30%), Positives = 53/119 (44%), Gaps = 4/119 (3%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHP--DSKVEVLPMDLSSDEK 207 A+ GIG + A G ++I + RN+ E I + P S+ +DLS Sbjct: 129 ANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLS---- 184 Query: 208 SLKEVVHSAESLFSSAG-IDYMMHNA-AFERPKRGALEETEEGLKATFKVNVFGTITLT 378 SL+ V E + S IDY++ NA F P T +GL+ TF+V+ LT Sbjct: 185 SLRSVQRFVEEIKQSVSHIDYLILNAGVFALP----YTRTVDGLETTFQVSHLSHFYLT 239
>YXJF_BACSU (P42317) Hypothetical oxidoreductase yxjF (EC 1.-.-.-)| Length = 257 Score = 38.5 bits (88), Expect = 0.013 Identities = 34/158 (21%), Positives = 73/158 (46%), Gaps = 1/158 (0%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GI ++ +FA GA +I+S E E+ + + D+ +P D++ E + Sbjct: 11 AAGGIRFEIAREFAREGASVIVSDLRPEACEKAASKLAEEGFDAAA--IPYDVTK-EAQV 67 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEE-TEEGLKATFKVNVFGTITLTRLLA 390 + V+ + + +D +++NA + +EE + + KV + + + Sbjct: 68 ADTVNVIQKQYGR--LDILVNNAGIQHV--APIEEFPTDTFEQLIKVMLTAPFIAMKHVF 123 Query: 391 PFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNG 504 P M + G + ++S G V G++ Y+++KH + G Sbjct: 124 PIMKKQQFGRIINIASVNGLVGFAGKSAYNSAKHGVIG 161
>DHB4_MOUSE (P51660) Peroxisomal multifunctional enzyme type 2 (MFE-2)| (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.107) (3-alpha,7-alpha,12-alpha-trihydroxy-5 Length = 734 Score = 38.5 bits (88), Expect = 0.013 Identities = 45/185 (24%), Positives = 78/185 (42%), Gaps = 9/185 (4%) Frame = +1 Query: 1 RHEARLCG*RXASRGIGEVLSMQFASLGAKLILS---------ARNKEELERVKHNIMSK 153 R + R+ A G+G ++ FA GA +I++ + ++V I K Sbjct: 5 RFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVAEIRRK 64 Query: 154 HPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL 333 K + + EK +K +L + ID +++NA R R ++E Sbjct: 65 --GGKAVANYDSVEAGEKLVKT------ALDTFGRIDVVVNNAGILRD-RSFSRISDEDW 115 Query: 334 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFA 513 +V++ G+ +TR M + G ++ SSA+G GQA YSA+K + G Sbjct: 116 DIIHRVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCN 175 Query: 514 SLRSE 528 +L E Sbjct: 176 TLAIE 180
>RDH7_MOUSE (O88451) Retinol dehydrogenase 7 (EC 1.1.1.105)| (Cis-retinol/androgen dehydrogenase type 2) (CRAD-2) (cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2) Length = 316 Score = 38.5 bits (88), Expect = 0.013 Identities = 38/171 (22%), Positives = 79/171 (46%), Gaps = 2/171 (1%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G G +L+ Q G +++ + ++ E++++ ++E + +D++ E S+ Sbjct: 40 GFGNLLARQLDRRGMRVLAACLTEKGAEQLRNKT-----SDRLETVILDVTKTE-SIVAA 93 Query: 223 VHSAESLFSSAGIDYMMHNAAFERPKRGALEE--TEEGLKATFKVNVFGTITLTRLLAPF 396 + + G+ +++NA A+ E +E VN+ G I +T + P Sbjct: 94 TQWVKERVGNRGLWGLVNNAGI---CVFAINEWLKKEDFANILDVNLLGMIEVTLSMLP- 149 Query: 397 MLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 ++ + G V +SS+ G+V G Y SK+ + + SLR E+ G+K Sbjct: 150 LVRKARGRVVNISSSMGRVSLCGGG-YCISKYGVEAFSDSLRREISYFGVK 199
>RDH14_HUMAN (Q9HBH5) Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol| dehydrogenase PAN2) Length = 336 Score = 38.5 bits (88), Expect = 0.013 Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 13/148 (8%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKE-------ELERVKHNIMSKHPDSKV----EVL 180 A+ G+G + + LGA++I+ R++ +L R P+ V E++ Sbjct: 51 ANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELI 110 Query: 181 PMDLSSDEKSLKEV-VHSAESLFSSAGIDYMMHNAA-FERPKRGALEETEEGLKATFKVN 354 +L D SL+ V E L +D +++NA F+ P +TE+G + F VN Sbjct: 111 VREL--DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCP----YMKTEDGFEMQFGVN 164 Query: 355 VFGTITLTRLLAPFMLDRGMGHFVVMSS 438 G LT LL + VV+SS Sbjct: 165 HLGHFLLTNLLLGLLKSSAPSRIVVVSS 192
>TSC10_YARLI (Q6CE86) 3-ketodihydrosphingosine reductase TSC10 (EC 1.1.1.102)| (3-dehydrosphinganine reductase) (KDS reductase) Length = 372 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 10/174 (5%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPD----SKVEVLPMDLSSDE 204 S+G G L+ + GA +++ +R +LE I++KH + + DL+ +E Sbjct: 69 SQGAGAALAELCYTKGANVVIVSRTVSKLEAQVQKIVTKHEPVFEGQTIRYISADLTKEE 128 Query: 205 KSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRG-ALEETEEGLKATFKVNVFGTITL-- 375 ++++ V S E++ + + + AA + G L+ L F N + Sbjct: 129 EAIR--VFSEETMPAPPDVIFSCAGAA----ETGFILDFKASQLARAFSTNYLSALFFVH 182 Query: 376 ---TRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 TR+ + + + + SS P G Y ASK A+ SLR E Sbjct: 183 AGTTRMAKEPISPKNPRYVAIFSSVLAFYPLLGYGQYCASKAAVRSLIDSLRVE 236
>RDH12_HUMAN (Q96NR8) Retinol dehydrogenase 12 (EC 1.1.1.-) (All-trans and 9-cis| retinol dehydrogenase) Length = 316 Score = 37.7 bits (86), Expect = 0.022 Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 3/144 (2%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ + + AS GA++ ++ R+ + E I +S+V V +DL SD KS+ Sbjct: 47 ANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDL-SDTKSI 105 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + L + +++NA +T +G + VN G LT LL Sbjct: 106 RAFAEG--FLAEEKQLHILINNAGV---MMCPYSKTADGFETHLGVNHLGHFLLTYLLLE 160 Query: 394 FMLDRGMGHFVVMSSAA---GKVP 456 + V +SS A GK+P Sbjct: 161 QLKVSAPARVVNVSSVAHHIGKIP 184
>RDH11_MOUSE (Q9QYF1) Retinol dehydrogenase 11 (EC 1.1.1.-) (Retinal reductase| 1) (RalR1) (Prostate short-chain dehydrogenase/reductase 1) (Androgen-regulated short-chain dehydrogenase/reductase 1) (Short-chain aldehyde dehydrogenase) (SCALD) (Cell line M Length = 316 Score = 37.7 bits (86), Expect = 0.022 Identities = 34/135 (25%), Positives = 62/135 (45%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ + A GA++ L+ R+ ++ E I + +S+V V +DL +D KS+ Sbjct: 46 ANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLDL-ADTKSI 104 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + + + L + +++NA +T +G + VN G LT LL Sbjct: 105 R--AFAKDFLAEEKHLHLLINNAGV---MMCPYSKTADGFEMHIGVNHLGHFLLTHLLLE 159 Query: 394 FMLDRGMGHFVVMSS 438 + + V +SS Sbjct: 160 KLKESAPSRIVNLSS 174
>BUTA_STAAW (P66776) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 1/171 (0%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++GIG ++ + G K+ + N+E + + S +K + D+S+ + Sbjct: 13 AQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSD--GTKAIAIKADVSNRD---- 66 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT-LTRLLAP 393 +V ++ + G ++M N A P TEE K + VNV G + + Sbjct: 67 DVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQ 126 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 F G + +S AG PG +LY ++K A+ G +L ++GI Sbjct: 127 FKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGI 177
>BUTA_STAAS (Q6GCZ8) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 1/171 (0%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++GIG ++ + G K+ + N+E + + S +K + D+S+ + Sbjct: 13 AQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSD--GTKAIAIKADVSNRD---- 66 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT-LTRLLAP 393 +V ++ + G ++M N A P TEE K + VNV G + + Sbjct: 67 DVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQ 126 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 F G + +S AG PG +LY ++K A+ G +L ++GI Sbjct: 127 FKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGI 177
>BUTA_STAAR (Q6GKH9) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 1/171 (0%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++GIG ++ + G K+ + N+E + + S +K + D+S+ + Sbjct: 13 AQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSD--GTKAIAIKADVSNRD---- 66 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT-LTRLLAP 393 +V ++ + G ++M N A P TEE K + VNV G + + Sbjct: 67 DVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQ 126 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 F G + +S AG PG +LY ++K A+ G +L ++GI Sbjct: 127 FKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGI 177
>BUTA_STAAN (P99120) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 1/171 (0%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++GIG ++ + G K+ + N+E + + S +K + D+S+ + Sbjct: 13 AQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSD--GTKAIAIKADVSNRD---- 66 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT-LTRLLAP 393 +V ++ + G ++M N A P TEE K + VNV G + + Sbjct: 67 DVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQ 126 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 F G + +S AG PG +LY ++K A+ G +L ++GI Sbjct: 127 FKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGI 177
>BUTA_STAAM (P66775) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 1/171 (0%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++GIG ++ + G K+ + N+E + + S +K + D+S+ + Sbjct: 13 AQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSD--GTKAIAIKADVSNRD---- 66 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT-LTRLLAP 393 +V ++ + G ++M N A P TEE K + VNV G + + Sbjct: 67 DVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQ 126 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 F G + +S AG PG +LY ++K A+ G +L ++GI Sbjct: 127 FKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGI 177
>BUTA_STAAC (Q5HJP2) Acetoin(diacetyl) reductase (EC 1.1.1.5) (Acetoin| dehydrogenase) (AR) (Meso-2,3-butanediol dehydrogenase) Length = 258 Score = 37.7 bits (86), Expect = 0.022 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 1/171 (0%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLK 216 ++GIG ++ + G K+ + N+E + + S +K + D+S+ + Sbjct: 13 AQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSD--GTKAIAIKADVSNRD---- 66 Query: 217 EVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTIT-LTRLLAP 393 +V ++ + G ++M N A P TEE K + VNV G + + Sbjct: 67 DVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQ 126 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 F G + +S AG PG +LY ++K A+ G +L ++GI Sbjct: 127 FKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGI 177
>RIDH_KLEAE (P00335) Ribitol 2-dehydrogenase (EC 1.1.1.56) (RDH)| Length = 249 Score = 37.7 bits (86), Expect = 0.022 Identities = 33/172 (19%), Positives = 69/172 (40%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG + GAK++L R E+L ++ + +V+++ D Sbjct: 22 AASGIGLECARTLLGAGAKVVLIDREGEKLNKLVAELGENAFALQVDLMQAD-------- 73 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +V + + + G + H A E + +N+ R + P Sbjct: 74 -QVDNLLQGILQLTGRLDIFHANAGAYIGGPVAEGDPDVWDRVLHLNINAAFRCVRSVLP 132 Query: 394 FMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGIK 549 ++ + G + + AG VP + +Y+ASK A+ + + R ++ G++ Sbjct: 133 HLIAQKSGDIIFTAVIAGVVPVIWEPVYTASKFAVQAFVHTTRRQVAQYGVR 184
>PHAB_PARDE (P50204) Acetoacetyl-CoA reductase (EC 1.1.1.36)| Length = 242 Score = 37.4 bits (85), Expect = 0.028 Identities = 45/173 (26%), Positives = 67/173 (38%), Gaps = 3/173 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDL-SSDEKSL 213 SRGIG +S G + + ++ R + K V D ++ K + Sbjct: 11 SRGIGAAISKALKEAGYTVAANYAGNDDAARA-FTEETGIKTYKWSVADYDACAAGIKQV 69 Query: 214 KEVVHSAESLFSSAGI--DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLL 387 +E + L ++AGI D M H T + K N+ G +T + Sbjct: 70 EEELGPIAVLVNNAGITRDAMFHKM------------TPQQWKEVIDTNLTGLFNMTHPV 117 Query: 388 APFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M DR G V +SS G+ GQA YSA+K G+ +L E GI Sbjct: 118 WSGMRDRKYGRIVNISSINGQKGQAGQANYSAAKAGDLGFTKALAQEGARAGI 170
>YJGI_ECOLI (P39333) Hypothetical oxidoreductase yjgI (EC 1.-.-.-)| Length = 237 Score = 37.4 bits (85), Expect = 0.028 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 2/172 (1%) Frame = +1 Query: 37 SRGIGEVLSMQFASLGAKLILS-ARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 SRGIG + +F + GA + + A +K+ +R+ ++ + D S+D ++ Sbjct: 15 SRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQ-------ETGATAVFTD-SADRDAV 66 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 +VV S +D ++ NA ALE + + FK+N+ + A Sbjct: 67 IDVVRK------SGALDILVVNAGIGVFGE-ALELNADDIDRLFKINIHAPYHASVEAAR 119 Query: 394 FMLDRGMGHFVVMSSAAG-KVPTPGQALYSASKHALNGYFASLRSELCTKGI 546 M + G +++ S G ++P G A Y+ASK AL G L + +GI Sbjct: 120 QMPEGG--RILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGI 169
>TODD_PSEPU (P13859) Cis-toluene dihydrodiol dehydrogenase (EC 1.3.1.-)| Length = 275 Score = 37.4 bits (85), Expect = 0.028 Identities = 43/169 (25%), Positives = 71/169 (42%), Gaps = 7/169 (4%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G + ++ + GA++ + ++ LE ++ H D+ V V D+ S + + V Sbjct: 16 GLGRAIVDRYVAEGARVAVLDKSAAGLEALR----KLHGDAIVGV-EGDVRSLDSHREAV 70 Query: 223 VHSAES------LFSSAGI-DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 E+ L +AG+ DY+ + E + F+VNV G I + Sbjct: 71 ARCVEAFGKLDCLVGNAGVWDYLTQLVDIPD------DLISEAFEEMFEVNVKGYILAAK 124 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 P L + G + S AG P G LY+A KHA+ G L E Sbjct: 125 AALP-ALYQSKGSAIFTVSNAGFYPGGGGVLYTAGKHAVIGLIKQLAHE 172
>BNZE_PSEPU (P08088) Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC| 1.3.1.19) (Cis-benzene glycol dehydrogenase) Length = 275 Score = 37.4 bits (85), Expect = 0.028 Identities = 43/169 (25%), Positives = 71/169 (42%), Gaps = 7/169 (4%) Frame = +1 Query: 43 GIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEV 222 G+G + ++ + GA++ + ++ LE ++ H D+ V V D+ S + + V Sbjct: 16 GLGRAIVDRYVAEGARVAVLDKSAAGLEALR----KLHGDAIVGV-EGDVRSLDSHREAV 70 Query: 223 VHSAES------LFSSAGI-DYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTR 381 E+ L +AG+ DY+ + E + F+VNV G I + Sbjct: 71 ARCVEAFGKLDCLVGNAGVWDYLTQLVDIPD------DLISEAFEEMFEVNVKGYILAAK 124 Query: 382 LLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNGYFASLRSE 528 P L + G + S AG P G LY+A KHA+ G L E Sbjct: 125 AALP-ALYQSKGSAIFTVSNAGFYPGGGGVLYTAGKHAVIGLIKQLAHE 172
>RDH12_BOVIN (P59837) Retinol dehydrogenase 12 (EC 1.1.1.-) (Double substrate| specificity short chain dehydrogenase/reductase 2) Length = 316 Score = 37.4 bits (85), Expect = 0.028 Identities = 35/137 (25%), Positives = 61/137 (44%) Frame = +1 Query: 34 ASRGIGEVLSMQFASLGAKLILSARNKEELERVKHNIMSKHPDSKVEVLPMDLSSDEKSL 213 A+ GIG+ + + A GA++ ++ R+ + E I + +S+V V +DL SD KS+ Sbjct: 47 ANTGIGKETARELARRGARVYIACRDVLKGESAASEIQADTKNSQVLVRKLDL-SDTKSI 105 Query: 214 KEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGLKATFKVNVFGTITLTRLLAP 393 + L + +++NA +T +G + VN G LT LL Sbjct: 106 RAFAEG--FLAEEKQLHILINNAGV---MLCPYSKTADGFETHLAVNHLGHFLLTHLLLG 160 Query: 394 FMLDRGMGHFVVMSSAA 444 + + V +SS A Sbjct: 161 RLKESAPARVVNLSSVA 177
>ADH_BACOL (Q9NAR7) Alcohol dehydrogenase (EC 1.1.1.1)| Length = 258 Score = 37.4 bits (85), Expect = 0.028 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 3/138 (2%) Frame = +1 Query: 115 EELERVKHNIMSKHPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFER 294 E E +K + + +P +KV D+++ + S+K A+ + ID +++ A Sbjct: 40 ENAENIKA-LQAINPKTKVYYTKFDITN-KASIKSAF--ADVIAKVQYIDVLVNGA---- 91 Query: 295 PKRGALEETEEGLKATFKVNVFGTITLTRLLAPFM--LDRGMGHFVV-MSSAAGKVPTPG 465 G L T+ ++ T +N+ G I T P M +G G +V ++S G P P Sbjct: 92 ---GIL--TDPNVELTMNINLIGLINTTLEAIPLMDKNKKGRGGLIVNIASVLGLEPAPP 146 Query: 466 QALYSASKHALNGYFASL 519 A+Y ASK + G+ S+ Sbjct: 147 AAIYCASKFGVMGFSRSI 164
>ADH1_CERCA (P48814) Alcohol dehydrogenase 1 (EC 1.1.1.1)| Length = 257 Score = 37.0 bits (84), Expect = 0.037 Identities = 36/125 (28%), Positives = 60/125 (48%), Gaps = 3/125 (2%) Frame = +1 Query: 154 HPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL 333 +P +KV D+++ E S+K+ + A+ + ID +++ A G L T+ + Sbjct: 52 NPKTKVYYTKFDITNKE-SIKQSL--ADVISKVQHIDALINGA-------GIL--TDPNV 99 Query: 334 KATFKVNVFGTITLTRLLAPFM--LDRGMGHFVV-MSSAAGKVPTPGQALYSASKHALNG 504 + T +N+ G I T P M G G +V ++S G P P A+Y ASK + G Sbjct: 100 ELTMNINLIGLINTTLEALPLMDKNKHGRGGVIVNIASVLGLEPCPPAAVYCASKFGVVG 159 Query: 505 YFASL 519 + SL Sbjct: 160 FSRSL 164
>DHB4_RAT (P97852) Peroxisomal multifunctional enzyme type 2 (MFE-2)| (D-bifunctional protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) [Includes: D-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.107) (3-alpha,7-alpha,12-alpha-trihydroxy-5-b Length = 734 Score = 36.6 bits (83), Expect = 0.049 Identities = 41/177 (23%), Positives = 75/177 (42%), Gaps = 9/177 (5%) Frame = +1 Query: 1 RHEARLCG*RXASRGIGEVLSMQFASLGAKLILS---------ARNKEELERVKHNIMSK 153 R + R+ A G+G ++ FA GA ++++ + ++V I + Sbjct: 5 RFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVEEIRRR 64 Query: 154 HPDSKVEVLPMDLSSDEKSLKEVVHSAESLFSSAGIDYMMHNAAFERPKRGALEETEEGL 333 K + + EK +K +L + ID +++NA R R ++E Sbjct: 65 --GGKAVANYDSVEAGEKLVKT------ALDTFGRIDVVVNNAGILRD-RSFSRISDEDW 115 Query: 334 KATFKVNVFGTITLTRLLAPFMLDRGMGHFVVMSSAAGKVPTPGQALYSASKHALNG 504 +V++ G+ +TR M + G ++ +SA+G GQA YSA+K L G Sbjct: 116 DIIQRVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLG 172 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,658,226 Number of Sequences: 219361 Number of extensions: 1496573 Number of successful extensions: 5470 Number of sequences better than 10.0: 327 Number of HSP's better than 10.0 without gapping: 5125 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5361 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4488201198 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
