>PGTA_RAT (Q08602) Geranylgeranyl transferase type-2 alpha subunit (EC|
           2.5.1.60) (Geranylgeranyl transferase type II alpha
           subunit) (Rab geranylgeranyltransferase alpha subunit)
           (Rab geranyl-geranyltransferase alpha subunit) (Rab GG
           transferase alpha) (Ra
          Length = 567

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 36/73 (49%), Positives = 44/73 (60%), Gaps = 2/73 (2%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESK--QKIFSEEFELVIQALFTDPSDQSGWF 189
           I  NFSNYS+WH RS LL  L  Q   G + +  + +  +E ELV  A FTDP+DQS WF
Sbjct: 171 ITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLKELELVQNAFFTDPNDQSAWF 230

Query: 190 YHLWLLAQTSTPD 228
           YH WLL +    D
Sbjct: 231 YHRWLLGRAEPHD 243

>PGTA_PONPY (Q5NVK5) Geranylgeranyl transferase type-2 alpha subunit (EC|
           2.5.1.60) (Geranylgeranyl transferase type II alpha
           subunit) (Rab geranylgeranyltransferase alpha subunit)
           (Rab geranyl-geranyltransferase alpha subunit) (Rab GG
           transferase alpha) (
          Length = 567

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 36/73 (49%), Positives = 44/73 (60%), Gaps = 2/73 (2%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESK--QKIFSEEFELVIQALFTDPSDQSGWF 189
           I  NFSNYS+WH RS LL  L  Q   G + +  + +  +E ELV  A FTDP+DQS WF
Sbjct: 171 ITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWF 230

Query: 190 YHLWLLAQTSTPD 228
           YH WLL +    D
Sbjct: 231 YHRWLLGRADPQD 243

>PGTA_HUMAN (Q92696) Geranylgeranyl transferase type-2 alpha subunit (EC|
           2.5.1.60) (Geranylgeranyl transferase type II alpha
           subunit) (Rab geranylgeranyltransferase alpha subunit)
           (Rab geranyl-geranyltransferase alpha subunit) (Rab GG
           transferase alpha) (
          Length = 567

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 36/73 (49%), Positives = 44/73 (60%), Gaps = 2/73 (2%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESK--QKIFSEEFELVIQALFTDPSDQSGWF 189
           I  NFSNYS+WH RS LL  L  Q   G + +  + +  +E ELV  A FTDP+DQS WF
Sbjct: 171 ITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWF 230

Query: 190 YHLWLLAQTSTPD 228
           YH WLL +    D
Sbjct: 231 YHRWLLGRADPQD 243

>PGTA_MOUSE (Q9JHK4) Geranylgeranyl transferase type-2 alpha subunit (EC|
           2.5.1.60) (Geranylgeranyl transferase type II alpha
           subunit) (Rab geranylgeranyltransferase alpha subunit)
           (Rab geranyl-geranyltransferase alpha subunit) (Rab GG
           transferase alpha) (
          Length = 567

 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 36/73 (49%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESK--QKIFSEEFELVIQALFTDPSDQSGWF 189
           I  NFSNYS+WH RS LL  L  Q   G + +  + +   E ELV  A FTDP+DQS WF
Sbjct: 171 ITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPENVLLRELELVQNAFFTDPNDQSAWF 230

Query: 190 YHLWLLAQTSTPD 228
           YH WLL +    D
Sbjct: 231 YHRWLLGRAEPHD 243

>BET4_YEAST (Q00618) Geranylgeranyl transferase type-2 alpha subunit (EC|
           2.5.1.60) (Geranylgeranyl transferase type II alpha
           subunit) (Type II protein geranyl-geranyltransferase
           alpha subunit) (GGTase-II-alpha) (PGGT) (YPT1/SEC4
           proteins geranylgeranyltra
          Length = 327

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 26/65 (40%), Positives = 37/65 (56%)
 Frame = +1

Query: 13  KIGENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFY 192
           KI  N SNYSAWH R  ++S +  +   G  ++++    E   +I A+FTD  DQS WFY
Sbjct: 174 KINNNISNYSAWHQRVQIISRMFQKGEVG--NQKEYIRTEISYIINAMFTDAEDQSVWFY 231

Query: 193 HLWLL 207
             W +
Sbjct: 232 IKWFI 236

>BET4_CANAL (O93829) Geranylgeranyl transferase type-2 alpha subunit (EC|
           2.5.1.60) (Geranylgeranyl transferase type II alpha
           subunit) (Type II protein geranyl-geranyltransferase
           alpha subunit) (GGTase-II-alpha) (PGGT) (YPT1/SEC4
           proteins geranylgeranyltra
          Length = 371

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 19/84 (22%)
 Frame = +1

Query: 13  KIGENFSNYSAWHNRSILLS---NLLIQRREGFESKQKIFSE----------------EF 135
           KI ++FSN+SAWHNR+ L+    NL+ Q+++  +   KIF +                + 
Sbjct: 188 KIQKDFSNFSAWHNRTKLIPKIYNLIQQQQQQQQKDGKIFGDLPGIELFQNPILLLKNDL 247

Query: 136 ELVIQALFTDPSDQSGWFYHLWLL 207
           E++   ++  P D S W Y  WLL
Sbjct: 248 EMIKTGVYMSPEDTSVWLYLYWLL 271

>RAM2_CANAL (Q9Y765) Protein farnesyltransferase/geranylgeranyltransferase type|
           I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX
           farnesyltransferase alpha subunit) (Ras proteins
           prenyltransferase alpha) (FTase-alpha) (Type I protein
           geranyl-geranyltransf
          Length = 306

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 15/62 (24%), Positives = 29/62 (46%)
 Frame = +1

Query: 22  ENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYHLW 201
           +N  NY  W+ R +++  ++      F+  +     EF ++   L +DP +   W Y  W
Sbjct: 98  DNEKNYQIWNYRQLIIGQIMELNNNDFDPYR-----EFPILEAMLSSDPKNHHVWSYRKW 152

Query: 202 LL 207
           L+
Sbjct: 153 LV 154

>PFTA_MOUSE (Q61239) Protein farnesyltransferase/geranylgeranyltransferase type|
           I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX
           farnesyltransferase alpha subunit) (Ras proteins
           prenyltransferase alpha) (FTase-alpha) (Type I protein
           geranyl-geranyltransf
          Length = 377

 Score = 32.3 bits (72), Expect = 0.73
 Identities = 19/72 (26%), Positives = 29/72 (40%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYH 195
           I E   NY  WH+R +L+  L            K  S+E E +   L  D  +   W + 
Sbjct: 159 IEEQPKNYQVWHHRRVLVEWL------------KDPSQELEFIADILSQDAKNYHAWQHR 206

Query: 196 LWLLAQTSTPDN 231
            W++ +    DN
Sbjct: 207 QWVIQEFRLWDN 218



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
 Frame = +1

Query: 22  ENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYHLW 201
           E+  N S W+ R  ++SN       G+ S + +   E +  ++ +   P ++S W Y   
Sbjct: 229 EDVRNNSVWNQRHFVISN-----TTGY-SDRAVLEREVQYTLEMIKLVPHNESAWNYLKG 282

Query: 202 LLAQTSTPDNP----QLISSWPSHGA 267
           +L        P    QL+   PSH +
Sbjct: 283 ILQDRGLSRYPNLLNQLLDLQPSHSS 308

>PFTA_RAT (Q04631) Protein farnesyltransferase/geranylgeranyltransferase type|
           I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX
           farnesyltransferase alpha subunit) (Ras proteins
           prenyltransferase alpha) (FTase-alpha) (Type I protein
           geranyl-geranyltransfer
          Length = 377

 Score = 32.0 bits (71), Expect = 0.95
 Identities = 19/72 (26%), Positives = 29/72 (40%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYH 195
           I E   NY  WH+R +L+  L            K  S+E E +   L  D  +   W + 
Sbjct: 159 IEEQPKNYQVWHHRRVLVEWL------------KDPSQELEFIADILNQDAKNYHAWQHR 206

Query: 196 LWLLAQTSTPDN 231
            W++ +    DN
Sbjct: 207 QWVIQEFRLWDN 218



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 18/67 (26%), Positives = 27/67 (40%)
 Frame = +1

Query: 25  NFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYHLWL 204
           N +NY+ WH R +LL +L           QK   EE   +I  +   P +   W +   L
Sbjct: 127 NAANYTVWHFRRVLLRSL-----------QKDLQEEMNYIIAIIEEQPKNYQVWHHRRVL 175

Query: 205 LAQTSTP 225
           +     P
Sbjct: 176 VEWLKDP 182



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
 Frame = +1

Query: 22  ENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYHLW 201
           E+  N S W+ R  ++SN       G+ S + +   E +  ++ +   P ++S W Y   
Sbjct: 229 EDVRNNSVWNQRHFVISN-----TTGY-SDRAVLEREVQYTLEMIKLVPHNESAWNYLKG 282

Query: 202 LLAQTSTPDNP----QLISSWPSHGA 267
           +L        P    QL+   PSH +
Sbjct: 283 ILQDRGLSRYPNLLNQLLDLQPSHSS 308

>PFTA_BOVIN (P29702) Protein farnesyltransferase/geranylgeranyltransferase type|
           I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX
           farnesyltransferase alpha subunit) (Ras proteins
           prenyltransferase alpha) (FTase-alpha) (Type I protein
           geranyl-geranyltransf
          Length = 340

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 18/72 (25%), Positives = 29/72 (40%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYH 195
           I E   NY  WH+R +L+  L            +  S+E E +   L  D  +   W + 
Sbjct: 120 IEEQPKNYQVWHHRRVLVEWL------------RDPSQELEFIADILTQDAKNYHAWQHR 167

Query: 196 LWLLAQTSTPDN 231
            W++ +    DN
Sbjct: 168 QWVIQEFKLWDN 179

>PFTA_HUMAN (P49354) Protein farnesyltransferase/geranylgeranyltransferase type|
           I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX
           farnesyltransferase alpha subunit) (Ras proteins
           prenyltransferase alpha) (FTase-alpha) (Type I protein
           geranyl-geranyltransf
          Length = 379

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 18/72 (25%), Positives = 29/72 (40%)
 Frame = +1

Query: 16  IGENFSNYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWFYH 195
           I E   NY  WH+R +L+  L            +  S+E E +   L  D  +   W + 
Sbjct: 159 IEEQPKNYQVWHHRRVLVEWL------------RDPSQELEFIADILNQDAKNYHAWQHR 206

Query: 196 LWLLAQTSTPDN 231
            W++ +    DN
Sbjct: 207 QWVIQEFKLWDN 218

>YETS4_MOUSE (Q9CR11) YEATS domain-containing protein 4|
          Length = 227

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = +1

Query: 130 EFELVIQALFTDPSDQSGWFYHLWLLAQTST 222
           EFE++I+  F DP+++    YHL  L Q+ T
Sbjct: 95  EFEIIIKIFFIDPNERPVTLYHLLKLFQSDT 125

>YETS4_HUMAN (O95619) YEATS domain-containing protein 4 (Glioma-amplified|
           sequence-41) (Gas41) (NuMA-binding protein 1) (NuBI-1)
           (NuBI1)
          Length = 227

 Score = 31.2 bits (69), Expect = 1.6
 Identities = 13/31 (41%), Positives = 20/31 (64%)
 Frame = +1

Query: 130 EFELVIQALFTDPSDQSGWFYHLWLLAQTST 222
           EFE++I+  F DP+++    YHL  L Q+ T
Sbjct: 95  EFEIIIKIFFIDPNERPVTLYHLLKLFQSDT 125

>PFTA_SCHPO (O60052) Protein farnesyltransferase/geranylgeranyltransferase type|
           I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX
           farnesyltransferase alpha subunit) (Ras proteins
           prenyltransferase alpha) (FTase-alpha) (Type I protein
           geranyl-geranyltransf
          Length = 294

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
 Frame = +1

Query: 13  KIGENFS-NYSAWHNRSILLSNLLIQRREGFESKQKIFSEEFELVIQALFTDPSDQSGWF 189
           +I E+F  NY  WH+R  +LS              K +  E E   +    D  +   W 
Sbjct: 102 EIAEDFQKNYQVWHHRQKILS------------LTKNYERELEFTKKMFEIDSKNYHVWS 149

Query: 190 YHLWLL 207
           Y +W+L
Sbjct: 150 YRVWIL 155

>PFTA_LYCES (P93227) Protein farnesyltransferase/geranylgeranyltransferase type|
           I alpha subunit (EC 2.5.1.58) (EC 2.5.1.59) (CAAX
           farnesyltransferase alpha subunit) (Ras proteins
           prenyltransferase alpha) (FTase-alpha) (Type I protein
           geranyl-geranyltransf
          Length = 346

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 19/64 (29%), Positives = 25/64 (39%), Gaps = 1/64 (1%)
 Frame = +1

Query: 19  GENFSNYSAWHNRSILLSNLLIQR-REGFESKQKIFSEEFELVIQALFTDPSDQSGWFYH 195
           GEN  NY  WH+R  L   L         E  +KIFS+           D  +   W + 
Sbjct: 107 GENTKNYQIWHHRRWLAEKLGADAVTNELEFTKKIFSQ-----------DAKNYHAWSHR 155

Query: 196 LWLL 207
            W+L
Sbjct: 156 QWVL 159

>FOXN1_MOUSE (Q61575) Forkhead box protein N1 (Transcription factor winged-helix|
           nude) (Hepatocyte nuclear factor 3 forkhead homolog 11)
           (HNF-3/forkhead homolog 11) (HFH-11)
          Length = 648

 Score = 28.9 bits (63), Expect = 8.1
 Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
 Frame = +1

Query: 148 QALFTDPSDQSGWFYHLWLLAQTSTP-DNPQLISSWPSHGAKL 273
           Q LF  P        HL L AQ  TP D+P    + PSHGAKL
Sbjct: 469 QPLFPQPDG------HLELQAQPGTPQDSPLPAHTPPSHGAKL 505


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,044,603
Number of Sequences: 219361
Number of extensions: 1258026
Number of successful extensions: 2846
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 2784
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2839
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3581144924
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)