ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags12p02 |
|---|---|
| Clone Library Name | barley_pub |
>FKB70_WHEAT (Q43207) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 559 Score = 248 bits (633), Expect(2) = 2e-66 Identities = 127/170 (74%), Positives = 145/170 (85%) Frame = +3 Query: 30 RPASEVEGAVPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVR 209 RPA+ GAVPPN++L IDLELVSWKTVT IGDDK+ILKKVLKE EGYERPN+GAVV V+ Sbjct: 240 RPAAGEGGAVPPNASLVIDLELVSWKTVTEIGDDKKILKKVLKEXEGYERPNEGAVVTVK 299 Query: 210 LIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGS 389 + GKL +GTVF KKGH+ EPFEFKTDEE VIEGLD V+ MKKGEVAL IPPE+A+GS Sbjct: 300 ITGKLQDGTVFLKKGHDEQEPFEFKTDEEAVIEGLDRAVLNMKKGEVALVTIPPEYAYGS 359 Query: 390 TETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 TE+K D A+VPPNSTV YEVELVSF K+KESWDL +N+EKIEAA KK+E Sbjct: 360 TESKQD-AIVPPNSTVIYEVELVSFVKDKESWDL-NNSEKIEAAGTKKEE 407 Score = 94.0 bits (232), Expect = 2e-19 Identities = 56/154 (36%), Positives = 84/154 (54%), Gaps = 2/154 (1%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL D+EL+SW +V I D I KK+LKEG+ +E P D V V+ +L++GT Sbjct: 132 IPANATLQFDVELLSWTSVRDIAKDGGIFKKILKEGDKWENPKDPDEVFVKYEARLEDGT 191 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKL--DL 410 V +K E EF + + L V TMKKGE L + P++ FG + Sbjct: 192 VVSK-----SEGVEFTVKDGHLCPALAKAVKTMKKGEKVLLAVKPQYGFGEMGRPAAGEG 246 Query: 411 AVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKI 512 VPPN+++ ++ELVS++ E D K +K+ Sbjct: 247 GAVPPNASLVIDLELVSWKTVTEIGDDKKILKKV 280 Score = 80.9 bits (198), Expect = 2e-15 Identities = 46/112 (41%), Positives = 68/112 (60%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTT 323 KK+LKEGEG++ P G V V G L +G F + D+ F+FK + QVI+G D Sbjct: 45 KKLLKEGEGWDTPEVGDEVEVHYTGTLLDGKKFDSS-RDRDDTFKFKLGQGQVIKGWDQG 103 Query: 324 VVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKE 479 + TMKKGE AL IPPE A+G + + +P N+T+ ++VEL+S+ ++ Sbjct: 104 IKTMKKGENALFTIPPELAYGESGSP---PTIPANATLQFDVELLSWTSVRD 152 Score = 23.9 bits (50), Expect(2) = 2e-66 Identities = 8/10 (80%), Positives = 9/10 (90%) Frame = +2 Query: 2 PQYGFGEQGK 31 PQYGFGE G+ Sbjct: 231 PQYGFGEMGR 240
>FKB70_ARATH (Q38931) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Peptidylprolyl isomerase ROF1) Length = 551 Score = 246 bits (627), Expect(2) = 4e-66 Identities = 121/173 (69%), Positives = 150/173 (86%), Gaps = 1/173 (0%) Frame = +3 Query: 24 KXRPASEVEGAVPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVR 203 K +PAS EGAVPPN+TL I+LELVSWKTV+ + DD +++KKVLKEG+GYERPN+GAVV+ Sbjct: 235 KGKPASAGEGAVPPNATLEINLELVSWKTVSEVTDDNKVVKKVLKEGDGYERPNEGAVVK 294 Query: 204 VRLIGKLDNGTVFTKKGH-EGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHA 380 V+LIGKL +GTVF KKGH E +EPFEFKTDEEQV++GLD V+ MKKGEVAL I PE+A Sbjct: 295 VKLIGKLQDGTVFLKKGHGENEEPFEFKTDEEQVVDGLDRAVMKMKKGEVALVTIDPEYA 354 Query: 381 FGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 FGS E++ +LAVVPPNSTV YEV+L++F+KE+ESWD+ + EKIEAASKKK+E Sbjct: 355 FGSNESQQELAVVPPNSTVTYEVDLLTFDKERESWDMNTE-EKIEAASKKKEE 406 Score = 84.7 bits (208), Expect = 1e-16 Identities = 53/154 (34%), Positives = 76/154 (49%), Gaps = 2/154 (1%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL D+EL+ W +V I D + KK+L GE +E P D V V+ KL++GT Sbjct: 129 IPANATLQFDVELLKWDSVKDICKDGGVFKKILAVGEKWENPKDLDEVLVKFEAKLEDGT 188 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFG--STETKLDL 410 V K + EF + L V TMKKGE L + P++ FG Sbjct: 189 VVGK-----SDGVEFTVKDGHFCPALTKAVKTMKKGEKVLLTVKPQYGFGEKGKPASAGE 243 Query: 411 AVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKI 512 VPPN+T+ +ELVS++ E D +K+ Sbjct: 244 GAVPPNATLEINLELVSWKTVSEVTDDNKVVKKV 277 Score = 83.6 bits (205), Expect = 3e-16 Identities = 54/153 (35%), Positives = 83/153 (54%), Gaps = 4/153 (2%) Frame = +3 Query: 84 DLELVSWKTVTLIGDDKRIL----KKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKK 251 D++ + +G++K I KK+LKEGEGYE P +G V V G L +GT F Sbjct: 18 DMDFGDGASFLKVGEEKEIQQGLKKKLLKEGEGYETPENGDEVEVHYTGTLLDGTKFDSS 77 Query: 252 GHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNS 431 + PF+F + QVI+G D + TMKKGE A+ IP E A+G + + +P N+ Sbjct: 78 -RDRATPFKFTLGQGQVIKGWDIGIKTMKKGENAVFTIPAELAYGESGSP---PTIPANA 133 Query: 432 TVFYEVELVSFEKEKESWDLKSNAEKIEAASKK 530 T+ ++VEL+ ++ K+ +KI A +K Sbjct: 134 TLQFDVELLKWDSVKDICKDGGVFKKILAVGEK 166 Score = 25.4 bits (54), Expect(2) = 4e-66 Identities = 9/10 (90%), Positives = 10/10 (100%) Frame = +2 Query: 2 PQYGFGEQGK 31 PQYGFGE+GK Sbjct: 228 PQYGFGEKGK 237
>FKBP4_MOUSE (P30416) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 457 Score = 94.0 bits (232), Expect = 2e-19 Identities = 60/169 (35%), Positives = 97/169 (57%), Gaps = 9/169 (5%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGD-DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNG 233 +PPN+TL ++EL +K L + D I++++ GEGY RPNDGA+V V L Sbjct: 121 IPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYARPNDGAMVEVAL------- 173 Query: 234 TVFTKKGHEGDEPFE-----FKTDEEQVIE---GLDTTVVTMKKGEVALARIPPEHAFGS 389 +G+ D F+ F+ E + ++ GL+ + M+KGE ++ + P +AFGS Sbjct: 174 -----EGYHKDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGS 228 Query: 390 TETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKD 536 + +PP++ + YEV L SFEK KESW++ S+AEK+E ++ K+ Sbjct: 229 VGK--ERFQIPPHAELRYEVRLKSFEKAKESWEM-SSAEKLEQSNIVKE 274 Score = 67.4 bits (163), Expect = 2e-11 Identities = 43/115 (37%), Positives = 61/115 (53%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK + +EG G E P G V V G L +GT F D+ F F + +VI+ Sbjct: 29 DEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDK-FSFDLGKGEVIK 87 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMK GEV PE+A+G+ + +PPN+T+ +EVEL F+ E Sbjct: 88 AWDIAVATMKVGEVCHITCKPEYAYGAAGSP---PKIPPNATLVFEVELFEFKGE 139
>FKBP4_RABIT (P27124) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 457 Score = 92.4 bits (228), Expect = 7e-19 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 4/164 (2%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGD-DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNG 233 +PPN+TL ++EL +K L D D I++++ GEGY RPNDGA+V V L G Sbjct: 121 IPPNATLVFEVELFEFKGEDLTDDEDGGIIRRIRTRGEGYARPNDGAIVEVALEG----- 175 Query: 234 TVFTKKGHEGDEPFEFKTDEEQVIE---GLDTTVVTMKKGEVALARIPPEHAFGSTETKL 404 + K F+ E + ++ GL+ + M+KGE ++ + P +AFG+ Sbjct: 176 --YYKDRLFDQRELRFEVGEGESLDLPCGLEKAIQRMEKGEHSILYLKPSYAFGNAGK-- 231 Query: 405 DLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKD 536 + +PP + + YEV L SFEK KESW++ S+ EK+E ++ K+ Sbjct: 232 EKFQIPPYAELKYEVHLKSFEKAKESWEM-SSEEKLEQSAIVKE 274 Score = 67.8 bits (164), Expect = 2e-11 Identities = 43/115 (37%), Positives = 61/115 (53%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK + +EG G E P G V V G L +GT F D+ F F + +VI+ Sbjct: 29 DEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDK-FSFDLGKGEVIK 87 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMK GE+ PE+A+GS + +PPN+T+ +EVEL F+ E Sbjct: 88 AWDIAVATMKVGELCRITCKPEYAYGSAGSP---PKIPPNATLVFEVELFEFKGE 139
>FKBP4_HUMAN (Q02790) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP-binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506-binding protein) (FKBP59) Length = 458 Score = 90.5 bits (223), Expect = 3e-18 Identities = 56/164 (34%), Positives = 92/164 (56%), Gaps = 4/164 (2%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGD-DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNG 233 +PPN+TL ++EL +K L + D I++++ GEGY +PN+GA+V V L G Sbjct: 121 IPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEG----- 175 Query: 234 TVFTKKGHEGDEPFEFKTDEEQVIE---GLDTTVVTMKKGEVALARIPPEHAFGSTETKL 404 + K F+ E + ++ GL+ + M+KGE ++ + P +AFGS Sbjct: 176 --YYKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGK-- 231 Query: 405 DLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKD 536 + +PPN+ + YE+ L SFEK KESW++ S EK+E ++ K+ Sbjct: 232 EKFQIPPNAELKYELHLKSFEKAKESWEMNSE-EKLEQSTIVKE 274 Score = 68.2 bits (165), Expect = 1e-11 Identities = 43/115 (37%), Positives = 61/115 (53%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK + +EG G E P G V V G L +GT F D+ F F + +VI+ Sbjct: 29 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDK-FSFDLGKGEVIK 87 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D + TMK GEV PE+A+GS + +PPN+T+ +EVEL F+ E Sbjct: 88 AWDIAIATMKVGEVCHITCKPEYAYGSAGSP---PKIPPNATLVFEVELFEFKGE 139
>FKBP5_SAGOE (Q9XSI2) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 86.3 bits (212), Expect = 5e-17 Identities = 56/162 (34%), Positives = 91/162 (56%), Gaps = 1/162 (0%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL ++EL+++K L+ +D I+++ + GEGY PN+GA V++ L G+ G Sbjct: 122 IPSNATLFFEVELLNFKGEDLL-EDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRC-GGR 179 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 VF + D F E+ I G+D + M++ E + + P + FG E Sbjct: 180 VFDCR----DVAFTVGEGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFG--EAGKPKF 233 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 + PN+ + YEV L SFEK KESW++ + EK+E A+ K+E Sbjct: 234 GIEPNAELIYEVTLKSFEKAKESWEMDTK-EKLEQAAIVKEE 274 Score = 83.6 bits (205), Expect = 3e-16 Identities = 49/115 (42%), Positives = 68/115 (59%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK V + G G E P G V V GKL NG F H+ +EPF F + QVI+ Sbjct: 30 DRGVLKIVKRVGHGEETPMIGDKVYVHYNGKLSNGKKFDSS-HDRNEPFVFSIGKGQVIK 88 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMKKGE+ PE+A+G+T + L +P N+T+F+EVEL++F+ E Sbjct: 89 AWDIGVSTMKKGEICHLLCKPEYAYGATGS---LPKIPSNATLFFEVELLNFKGE 140
>FKBP5_PONPY (Q5RF88) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 457 Score = 85.9 bits (211), Expect = 7e-17 Identities = 55/162 (33%), Positives = 90/162 (55%), Gaps = 1/162 (0%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL ++EL+ +K L +D I+++ ++GEGY PN+GA V + L G+ G Sbjct: 122 IPSNATLFFEIELLDFKGEDLF-EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGR 179 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 +F + D F E+ VI G+D + M++ E + + P + FG E Sbjct: 180 MFDCR----DVAFTVGEGEDHVIPIGIDKALEKMQREEQCILYLGPRYGFG--EAGKPKF 233 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 + PN+ + YEV L SFEK KESW++ + EK+E A+ K++ Sbjct: 234 GIEPNAELIYEVTLKSFEKAKESWEMDTK-EKLEQAAIVKEK 274 Score = 82.8 bits (203), Expect = 6e-16 Identities = 48/115 (41%), Positives = 66/115 (57%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK V + G G E P G V V GKL NG F H+ +EPF F + QVI+ Sbjct: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS-HDRNEPFVFSLGKGQVIK 88 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMKKGE+ PE+A+GS + L +P N+T+F+E+EL+ F+ E Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAGS---LPKIPSNATLFFEIELLDFKGE 140
>FKBP5_AOTNA (Q9XT11) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 84.7 bits (208), Expect = 1e-16 Identities = 55/162 (33%), Positives = 90/162 (55%), Gaps = 1/162 (0%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL ++EL+ +K L+ +D I+++ + GEGY PN+GA V++ L G+ G Sbjct: 122 IPSNATLFFEIELLDFKGEDLL-EDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRC-GGR 179 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 VF + D F E+ I G+D + M++ E + + P + FG E Sbjct: 180 VFDCR----DVAFTVGEGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFG--EAGKPKF 233 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 + PN+ + YEV L SFEK KESW++ + EK+E A+ K++ Sbjct: 234 GIEPNAELIYEVTLKSFEKAKESWEMDTK-EKLEQAAIVKEK 274 Score = 83.6 bits (205), Expect = 3e-16 Identities = 48/115 (41%), Positives = 67/115 (58%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK V + G G E P G V V GKL NG F H+ +EPF F + QVI+ Sbjct: 30 DRGVLKIVKRVGHGEETPMIGDKVYVHYNGKLSNGKKFDSS-HDRNEPFVFSIGKGQVIK 88 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMKKGE+ PE+A+G+T + L +P N+T+F+E+EL+ F+ E Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGATGS---LPKIPSNATLFFEIELLDFKGE 140
>FKBP5_MOUSE (Q64378) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) Length = 456 Score = 84.3 bits (207), Expect = 2e-16 Identities = 52/160 (32%), Positives = 86/160 (53%), Gaps = 1/160 (0%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL ++EL+ +K L +D +++++ ++GEGY PN+GA V+V L G T Sbjct: 122 IPSNATLFFEIELLDFKGEDLF-EDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRT 180 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 + D F E+ I G+D +V M++ E + + P + FG E Sbjct: 181 FDCR-----DVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFG--EAGKPKF 233 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKK 533 + PN+ + YEV L SFEK KESW++ + + +AA K+ Sbjct: 234 GIDPNAELMYEVTLKSFEKAKESWEMDTKEKLTQAAIVKE 273 Score = 72.4 bits (176), Expect = 8e-13 Identities = 44/115 (38%), Positives = 62/115 (53%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK V + G E P G V V G L +G F H+ +PF F + QVI+ Sbjct: 30 DRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLSDGKKFDSS-HDRKKPFAFSLGQGQVIK 88 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMKKGE+ PE+A+GS L +P N+T+F+E+EL+ F+ E Sbjct: 89 AWDIGVSTMKKGEICHLLCKPEYAYGSAG---HLQKIPSNATLFFEIELLDFKGE 140
>FKBP5_SAIBB (Q9XSH5) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 84.3 bits (207), Expect = 2e-16 Identities = 55/162 (33%), Positives = 90/162 (55%), Gaps = 1/162 (0%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL ++EL+ +K L+ +D I+++ + GEGY PN+GA V++ L G+ G Sbjct: 122 IPSNATLFFEVELLDFKGEDLL-EDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRC-GGR 179 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 VF + D F E+ I G+D + M++ E + + P + FG E Sbjct: 180 VFDCR----DVAFTVGEGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFG--EAGKPKF 233 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 + PN+ + YEV L SFEK KESW++ + EK+E A+ K++ Sbjct: 234 GIEPNAELIYEVTLKSFEKAKESWEMDTK-EKLEQAAIVKEK 274 Score = 82.8 bits (203), Expect = 6e-16 Identities = 49/115 (42%), Positives = 67/115 (58%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK V + G G E P G V V GKL NG F H+ +EPF F + QVI+ Sbjct: 30 DRGVLKIVKRVGHGEETPMIGDRVYVHYNGKLANGKKFDSS-HDRNEPFVFSIGKGQVIK 88 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMKKGE+ PE+A+G+T + L +P N+T+F+EVEL+ F+ E Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGATGS---LPKIPSNATLFFEVELLDFKGE 140
>FKBP5_HUMAN (Q13451) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-bindin Length = 457 Score = 83.2 bits (204), Expect = 4e-16 Identities = 54/162 (33%), Positives = 89/162 (54%), Gaps = 1/162 (0%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL ++EL+ +K L +D I+++ ++GEGY PN+GA V + L G+ G Sbjct: 122 IPSNATLFFEIELLDFKGEDLF-EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGR 179 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 +F + D F E+ I G+D + M++ E + + P + FG E Sbjct: 180 MFDCR----DVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFG--EAGKPKF 233 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 + PN+ + YEV L SFEK KESW++ + EK+E A+ K++ Sbjct: 234 GIEPNAELIYEVTLKSFEKAKESWEMDTK-EKLEQAAIVKEK 274 Score = 82.8 bits (203), Expect = 6e-16 Identities = 48/115 (41%), Positives = 66/115 (57%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK V + G G E P G V V GKL NG F H+ +EPF F + QVI+ Sbjct: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS-HDRNEPFVFSLGKGQVIK 88 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMKKGE+ PE+A+GS + L +P N+T+F+E+EL+ F+ E Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAGS---LPKIPSNATLFFEIELLDFKGE 140
>FKBP5_CERAE (Q95L05) FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 82.8 bits (203), Expect = 6e-16 Identities = 47/115 (40%), Positives = 66/115 (57%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIE 308 D+ +LK V + G G E P G V V GKL NG F H+ +EPF F + QVI+ Sbjct: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFNSS-HDRNEPFVFSLGKSQVIK 88 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 D V TMKKGE+ PE+A+GS + + +P N+T+F+E+EL+ F+ E Sbjct: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAGS---VPKIPSNATLFFEIELLDFKGE 140 Score = 81.6 bits (200), Expect = 1e-15 Identities = 52/162 (32%), Positives = 87/162 (53%), Gaps = 1/162 (0%) Frame = +3 Query: 57 VPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT 236 +P N+TL ++EL+ +K L+ +D I+++ ++GEGY PN+GA V + L G+ Sbjct: 122 IPSNATLFFEIELLDFKGEDLL-EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGERM 180 Query: 237 VFTKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 + D F E+ I G+D + M++ E + + P + FG E Sbjct: 181 FDCR-----DVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFG--EAGKPKF 233 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 + PN+ + YEV L SFEK KESW++ + EK+E A+ K++ Sbjct: 234 GIEPNAELIYEVTLKSFEKAKESWEMDTK-EKLEQAAIVKEK 274
>FKB59_DROME (Q9VL78) FK506-binding protein 59 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (dFKBP59) Length = 439 Score = 78.2 bits (191), Expect = 1e-14 Identities = 45/140 (32%), Positives = 77/140 (55%), Gaps = 2/140 (1%) Frame = +3 Query: 120 IGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQ 299 + D +LK++LKEG G E P+ G V + G+L +GT F +EPFEF + Sbjct: 9 LSGDGGVLKEILKEGTGTETPHSGCTVSLHYTGRLVDGTEF-DSSLSRNEPFEFSLGKGN 67 Query: 300 VIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKE 479 VI+ D V TMK GE P +A+G+ + +PP++T+ +E+E++ ++ E Sbjct: 68 VIKAFDMGVATMKLGERCFLTCAPNYAYGAAGSP---PAIPPDATLIFELEMLGWKGEDL 124 Query: 480 SWDLKSNAEK--IEAASKKK 533 S + + ++ +EA+ KK+ Sbjct: 125 SPNQDGSIDRTILEASDKKR 144 Score = 72.8 bits (177), Expect = 6e-13 Identities = 52/166 (31%), Positives = 86/166 (51%), Gaps = 4/166 (2%) Frame = +3 Query: 54 AVPPNSTLHIDLELVSWKTVTLI-GDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDN 230 A+PP++TL +LE++ WK L D I + +L+ + P+DGA V+ + G + Sbjct: 103 AIPPDATLIFELEMLGWKGEDLSPNQDGSIDRTILEASDKKRTPSDGAFVKAHISGSFE- 161 Query: 231 GTVFTKKGHEGDEPFEFKTDEEQ---VIEGLDTTVVTMKKGEVALARIPPEHAFGSTETK 401 G VF D EF E + +I+G++ + M GE + +I ++AFG+ Sbjct: 162 GRVFE------DRDVEFDYGEGKAIGIIDGVEIALEKMNVGETSRIKIQAKYAFGAKGN- 214 Query: 402 LDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 + +PPN+TV Y V+LV K E W L S+ E++ A K++ Sbjct: 215 -EEFKIPPNATVEYTVKLVDCGKGLEEWKL-SDEERLAEAKVYKEK 258
>FKBP3_RABIT (O46638) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) (Fragment) Length = 223 Score = 68.2 bits (165), Expect = 1e-11 Identities = 44/114 (38%), Positives = 61/114 (53%), Gaps = 6/114 (5%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVF------TKKGHEGDEPFEFKTDEEQVI 305 K VLK+G+ P G VV G L +GTVF + K + +P FK +VI Sbjct: 112 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSFKVGVGKVI 171 Query: 306 EGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 G D ++TM KGE A I PE A+G + + D A +PPN+ + +EVELV + Sbjct: 172 RGWDEALLTMSKGEKARLEIEPEWAYGK-KGQPD-AKIPPNAKLIFEVELVDID 223
>FKBP3_BOVIN (P26884) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 68.2 bits (165), Expect = 1e-11 Identities = 46/124 (37%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Frame = +3 Query: 114 TLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVF------TKKGHEGDEPF 275 TL + K VLK+G+ P G VV G L +GTVF + K + +P Sbjct: 103 TLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPL 162 Query: 276 EFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVEL 455 FK +VI G D ++TM KGE A I PE A+G + + D A +PPN+ + +EVEL Sbjct: 163 SFKVGIGKVIRGWDEALLTMSKGEKARLEIEPEWAYGK-KGQPD-AKIPPNAKLIFEVEL 220 Query: 456 VSFE 467 V + Sbjct: 221 VDID 224
>FKBP3_MOUSE (Q62446) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 67.8 bits (164), Expect = 2e-11 Identities = 45/124 (36%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Frame = +3 Query: 114 TLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVF------TKKGHEGDEPF 275 TL + K +LK+G+ P G VV G L +GTVF + K + +P Sbjct: 103 TLDEGPPKYTKSILKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKKKKNAKPL 162 Query: 276 EFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVEL 455 FK +VI G D ++TM KGE A I PE A+G + + D A +PPN+ + +EVEL Sbjct: 163 SFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGK-KGQPD-AKIPPNTKLIFEVEL 220 Query: 456 VSFE 467 V + Sbjct: 221 VDID 224
>FKBP3_HUMAN (Q00688) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (25 kDa FKBP) (FKBP-25) (Rapamycin-selective 25 kDa immunophilin) Length = 224 Score = 67.4 bits (163), Expect = 2e-11 Identities = 46/124 (37%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Frame = +3 Query: 114 TLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVF------TKKGHEGDEPF 275 TL + K VLK+G+ P G VV G L +GTVF + K + +P Sbjct: 103 TLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPL 162 Query: 276 EFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVEL 455 FK +VI G D ++TM KGE A I PE A+G + + D A +PPN+ + +EVEL Sbjct: 163 SFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGK-KGQPD-AKIPPNAKLTFEVEL 220 Query: 456 VSFE 467 V + Sbjct: 221 VDID 224
>PAS1_ARATH (Q7DMA9) Peptidyl-prolyl isomerase PASTICCINO1 (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 635 Score = 66.6 bits (161), Expect = 4e-11 Identities = 42/135 (31%), Positives = 71/135 (52%) Frame = +3 Query: 60 PPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTV 239 P + LH ++EL+ + + DD ++KK+L EGEG+E P + V+ R+ K +G V Sbjct: 132 PKDDELHFEIELLDFSKAKIASDDLGVIKKILNEGEGWESPREPYEVKARISAKSGDGHV 191 Query: 240 FTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVV 419 +EP+ F + +V +GL+ + TM + E A+ + ++ TE+ L L + Sbjct: 192 IFS---HTEEPYFFTFGKSEVPKGLEIGIGTMARKEKAVIYVRKQYL---TESPL-LHID 244 Query: 420 PPNSTVFYEVELVSF 464 V +EVELV F Sbjct: 245 QDLEEVHFEVELVHF 259 Score = 53.9 bits (128), Expect = 3e-07 Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 12/164 (7%) Frame = +3 Query: 75 LHIDLELVSWKTVTLIGDDKRILKKVLKEGEG---YERPNDGAVVRVRLIGKLDNG--TV 239 +H ++ELV + V + D R++K+ +++G G + P + + V G L N TV Sbjct: 250 VHFEVELVHFIQVRDMLGDGRLIKRRIRDGRGEFPMDCPLQDSRLSVHYKGMLLNEEKTV 309 Query: 240 F-TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAV 416 F K D+P EF + E V EG + M GE+AL PP++A+ Sbjct: 310 FYDSKIDNNDQPLEFSSGEGLVPEGFEMCTRLMLPGEIALVTCPPDYAYDKFPRP---PG 366 Query: 417 VPPNSTVFYEVELVSFEKEKESW------DLKSNAEKIEAASKK 530 V + V +E+EL+ FE ++ W + A+KI + + Sbjct: 367 VSEGAHVQWEIELLGFETPRD-WTGLNFQSIMDEADKIRSTGNR 409
>FKB12_DROME (P48375) 12 kDa FK506-binding protein (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Macrolide-binding protein) Length = 108 Score = 61.6 bits (148), Expect = 1e-09 Identities = 36/102 (35%), Positives = 56/102 (54%) Frame = +3 Query: 162 GEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKK 341 G+G P +G V V G LD+GT F + ++PF+F + +VI G D V + Sbjct: 11 GDGSTYPKNGQKVTVHYTGTLDDGTKFDSS-RDRNKPFKFTIGKGEVIRGWDEGVAQLSV 69 Query: 342 GEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 G+ A P++A+GS + V+PPNST+ ++VEL+ E Sbjct: 70 GQRAKLICSPDYAYGS---RGHPGVIPPNSTLTFDVELLKVE 108
>FKBP2_YARLI (Q6CGG3) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 144 Score = 61.2 bits (147), Expect = 2e-09 Identities = 41/118 (34%), Positives = 60/118 (50%) Frame = +3 Query: 138 ILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLD 317 ILKK+ E E ++ G V V GKL++GTVF G +P +F +VI G D Sbjct: 32 ILKKISPE-ECTQKARKGDTVSVHYTGKLEDGTVFDSSVERG-QPIQFPLGTGRVIPGWD 89 Query: 318 TTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDL 491 ++ M GE IPP A+G V+PP+ST+ + ELVS + + + +L Sbjct: 90 QGILGMCVGEKRKLTIPPHLAYGKQGAG---RVIPPDSTLIFTTELVSIDNDGDRDEL 144
>FKB1B_MOUSE (Q9Z2I2) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 61.2 bits (147), Expect = 2e-09 Identities = 33/107 (30%), Positives = 57/107 (53%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G + V G L NG F + ++PF+F+ +++VI+G + Sbjct: 5 ETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSS-RDRNKPFKFRIGKQEVIKGFEEGT 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A P+ A+G+T V+PPN+T+ ++VEL+S E Sbjct: 64 AQMSLGQRAKLTCTPDVAYGATGHP---GVIPPNATLIFDVELLSLE 107
>FKB1B_RAT (P97534) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 60.1 bits (144), Expect = 4e-09 Identities = 32/107 (29%), Positives = 57/107 (53%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G + V G L NG F + ++PF+F+ +++VI+G + Sbjct: 5 ETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSS-RDRNKPFKFRIGKQEVIKGFEEGA 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A P+ A+G+T V+PPN+T+ ++VEL++ E Sbjct: 64 AQMSLGQRAKLTCTPDVAYGATGHP---GVIPPNATLIFDVELLNLE 107
>FKB1A_XENLA (O42123) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 60.1 bits (144), Expect = 4e-09 Identities = 34/107 (31%), Positives = 56/107 (52%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + EG+G P G V V +G L+NG F + ++PF+F +VI G + V Sbjct: 5 ETITEGDGRTFPKKGQTVVVHYVGSLENGKKFDSS-RDRNKPFKFIIGRCEVIRGWEEGV 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A P+ A+G+T ++PPN+T+ ++VEL+ E Sbjct: 64 AQMSVGQRARLTCSPDFAYGATGHP---GIIPPNATLTFDVELLRLE 107
>FKB1A_BOVIN (P18203) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 59.3 bits (142), Expect = 7e-09 Identities = 32/107 (29%), Positives = 57/107 (53%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L++G F + ++PF+F +++VI G + V Sbjct: 5 ETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS-RDRNKPFKFVLGKQEVIRGWEEGV 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A I P++A+G+T ++PPN+T+ ++VEL+ E Sbjct: 64 AQMSVGQRAKLTISPDYAYGATGHP---GIIPPNATLIFDVELLKLE 107
>FKB1B_HUMAN (P68106) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) (h-FKBP-12) Length = 107 Score = 58.9 bits (141), Expect = 9e-09 Identities = 32/107 (29%), Positives = 56/107 (52%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L NG F + ++PF+F+ +++VI+G + Sbjct: 5 ETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS-RDRNKPFKFRIGKQEVIKGFEEGA 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A P+ A+G+T V+PPN+T+ ++VEL++ E Sbjct: 64 AQMSLGQRAKLTCTPDVAYGATGHP---GVIPPNATLIFDVELLNLE 107
>FKB1B_BOVIN (P68107) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 58.9 bits (141), Expect = 9e-09 Identities = 32/107 (29%), Positives = 56/107 (52%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L NG F + ++PF+F+ +++VI+G + Sbjct: 5 ETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS-RDRNKPFKFRIGKQEVIKGFEEGA 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A P+ A+G+T V+PPN+T+ ++VEL++ E Sbjct: 64 AQMSLGQRAKLTCTPDVAYGATGHP---GVIPPNATLIFDVELLNLE 107
>FKBP_DEBHA (Q6BX45) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 112 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/105 (32%), Positives = 54/105 (51%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 ++L+EG+G P G +V + G L+NG F G +PF+ QVI G DT + Sbjct: 10 EILQEGDGKTFPKPGDLVTIHYTGTLENGKKFDSSRDRG-KPFQCTIGVGQVIVGWDTGI 68 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVS 461 + G A IP A+G ++PPN+T+ ++VEL++ Sbjct: 69 PKLSVGSRAKLSIPGHEAYGDRGFP---GLIPPNATLLFDVELLN 110
>FKB1A_ASPFU (Q4WLV6) FK506-binding protein 1A (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 112 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/113 (30%), Positives = 59/113 (52%) Frame = +3 Query: 138 ILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLD 317 + K++ G G + P G V + G+L +G+ F + +EPF+ + +VI+G D Sbjct: 3 VTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKFDSSV-DRNEPFQTQIGTGRVIKGWD 61 Query: 318 TTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEK 476 V M GE A+ I P++ +G+ V+P NST+ +EVEL+ ++ Sbjct: 62 EGVPQMSLGEKAVLTITPDYGYGARGFP---PVIPGNSTLIFEVELLGINNKR 111
>FKBP3_CANAL (Q59VR3) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 426 Score = 58.2 bits (139), Expect = 1e-08 Identities = 42/120 (35%), Positives = 61/120 (50%) Frame = +3 Query: 108 TVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKT 287 T TL+G ++ + K G G GA V +R IGKL NG VF K + +PF FK Sbjct: 317 TKTLLGG---VITEDRKIGSG-ATAKSGAKVGIRYIGKLKNGKVFDK--NTSGKPFSFKL 370 Query: 288 DEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 + + I+G D V M G IPP+ +GS L +P NS + ++++LVS + Sbjct: 371 GKGECIKGFDLGVTGMAVGGERRVIIPPKMGYGSQA----LPGIPANSELTFDIKLVSLK 426
>FKB1B_RABIT (Q8HYX6) FK506-binding protein 1B (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase 1B) (PPIase 1B) (Rotamase 1B) (12.6 kDa FKBP) (FKBP-12.6) (Immunophilin FKBP12.6) Length = 107 Score = 57.4 bits (137), Expect = 3e-08 Identities = 32/107 (29%), Positives = 55/107 (51%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L NG F + ++PF+F+ +++VI+G + Sbjct: 5 ETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS-RDRNKPFKFRIGKQEVIKGFEEGA 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A P+ A+G+T V+PPN+T+ + VEL++ E Sbjct: 64 AQMSLGQRAKLTCTPDVAYGATGHP---GVIPPNATLIFGVELLNLE 107
>FKB1A_RABIT (P62943) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 57.4 bits (137), Expect = 3e-08 Identities = 31/107 (28%), Positives = 57/107 (53%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L++G F + ++PF+F +++VI G + V Sbjct: 5 ETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS-RDRNKPFKFMLGKQEVIRGWEEGV 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A I P++A+G+T ++PP++T+ ++VEL+ E Sbjct: 64 AQMSVGQRAKLTISPDYAYGATGHP---GIIPPHATLVFDVELLKLE 107
>FKB1A_HUMAN (P62942) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 57.4 bits (137), Expect = 3e-08 Identities = 31/107 (28%), Positives = 57/107 (53%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L++G F + ++PF+F +++VI G + V Sbjct: 5 ETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS-RDRNKPFKFMLGKQEVIRGWEEGV 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A I P++A+G+T ++PP++T+ ++VEL+ E Sbjct: 64 AQMSVGQRAKLTISPDYAYGATGHP---GIIPPHATLVFDVELLKLE 107
>FKB1A_RAT (Q62658) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 57.0 bits (136), Expect = 3e-08 Identities = 31/107 (28%), Positives = 57/107 (53%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L++G F + ++PF+F +++VI G + V Sbjct: 5 ETISSGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS-RDRNKPFKFTLGKQEVIRGWEEGV 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A I P++A+G+T ++PP++T+ ++VEL+ E Sbjct: 64 AQMSVGQRAKLIISPDYAYGATGHP---GIIPPHATLVFDVELLKLE 107
>FKBP4_SCHPO (O74191) FK506-binding protein 39 kDa (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 361 Score = 56.6 bits (135), Expect = 4e-08 Identities = 43/118 (36%), Positives = 60/118 (50%) Frame = +3 Query: 105 KTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFK 284 KT TL G ++ +K G G N G V +R IGKL+NG VF K + +PF F Sbjct: 251 KTRTLKGG---VVVTDVKTGSGASATN-GKKVEMRYIGKLENGKVFDK--NTKGKPFAFI 304 Query: 285 TDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 +VI G D V M++G IP A+G+ + +P NST+ +EV+LV Sbjct: 305 LGRGEVIRGWDVGVAGMQEGGERKITIPAPMAYGNQ----SIPGIPKNSTLVFEVKLV 358
>FKBP_SCHPO (O42993) FK506-binding protein (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) Length = 112 Score = 56.6 bits (135), Expect = 4e-08 Identities = 35/111 (31%), Positives = 52/111 (46%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTT 323 K+V+ G G + P G + + G L NG F G PF Q+I G D Sbjct: 5 KQVISSGNGQDFPKPGDRITMHYTGTLTNGKKFDSSVDRGS-PFVCTIGVGQLIRGWDEG 63 Query: 324 VVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEK 476 V M GE A I P++ +G ++PPNST+ ++VEL++ +K Sbjct: 64 VPKMSLGEKAKLTITPDYGYGPRGFP---GLIPPNSTLLFDVELLAINDKK 111
>FKBP4_NEUCR (Q7SCN0) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 467 Score = 56.2 bits (134), Expect = 6e-08 Identities = 42/106 (39%), Positives = 54/106 (50%), Gaps = 2/106 (1%) Frame = +3 Query: 156 KEGEGYERPNDGAVVRVRLIGKLDNGTVF--TKKGHEGDEPFEFKTDEEQVIEGLDTTVV 329 K G G N G V +R IGKL NG VF KKG PF FK + +VI+G D V Sbjct: 371 KVGTGRAAKN-GDRVGMRYIGKLQNGKVFDSNKKG----APFSFKLGKGEVIKGWDIGVA 425 Query: 330 TMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G IP A+GS L +PPNST+ ++V+L+ + Sbjct: 426 GMAVGGERRLTIPAHLAYGSRA----LPGIPPNSTLIFDVKLLEIK 467
>FKBP4_CANGA (Q6FK71) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 398 Score = 55.8 bits (133), Expect = 7e-08 Identities = 40/104 (38%), Positives = 55/104 (52%) Frame = +3 Query: 156 KEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTM 335 K GEG + G+ V +R IGKL NG VF K + +PF FK +VI+G D V M Sbjct: 302 KIGEG-PKAKKGSKVGMRYIGKLKNGKVFDK--NTSGKPFYFKLHRGEVIKGWDIGVTGM 358 Query: 336 KKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 G IP +A+G K L +P NS + ++V+LVS + Sbjct: 359 AIGGERRIVIPAPYAYG----KQTLPGIPANSELTFDVKLVSLK 398
>FKBP_CANGA (Q6FMA3) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/102 (32%), Positives = 50/102 (49%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 L G+G P G +V + G L+NG F G PF+ QVI+G D + Sbjct: 14 LSPGDGKTFPKQGDLVTIHYTGTLENGQKFDSSVDRGS-PFQCNIGVGQVIKGWDAGIPK 72 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + GE A IP +A+G ++PPN+T+ ++VEL+ Sbjct: 73 LSVGEKARLTIPGPYAYGPRGFP---GLIPPNATLIFDVELL 111
>FKBP3_YEAST (P38911) FK506-binding nuclear protein (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Proline rotamase) (Nucleolar proline isomerase) (FKBP-70) Length = 411 Score = 55.1 bits (131), Expect = 1e-07 Identities = 37/93 (39%), Positives = 50/93 (53%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 GA V +R IGKL NG VF K + +PF FK +VI+G D V M G IP Sbjct: 324 GARVGMRYIGKLKNGKVFDK--NTSGKPFAFKLGRGEVIKGWDIGVAGMSVGGERRIIIP 381 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 +A+G K L +P NS + ++V+LVS + Sbjct: 382 APYAYG----KQALPGIPANSELTFDVKLVSMK 410
>FKBP6_MOUSE (Q91XW8) FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 55.1 bits (131), Expect = 1e-07 Identities = 35/121 (28%), Positives = 63/121 (52%) Frame = +3 Query: 120 IGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQ 299 I D+ +LK +++EG G D +V+ V+ G L++ P K E+ Sbjct: 32 ISGDRGVLKDIIREGTGDTVTPDASVL-VKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDI 90 Query: 300 VIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKE 479 + G++ +++M+KGE+A P +A+G+ ++PPN+TV +E+EL+ F E Sbjct: 91 TLWGMELGLLSMRKGELARFLFKPAYAYGTLGCP---PLIPPNATVLFEIELIDFLDSAE 147 Query: 480 S 482 S Sbjct: 148 S 148
>FKBP4_GIBZE (Q4INZ9) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 495 Score = 55.1 bits (131), Expect = 1e-07 Identities = 38/95 (40%), Positives = 50/95 (52%), Gaps = 2/95 (2%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVF--TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALAR 362 G V VR IGKL NG F KKG +PF FK + QVI+G D V+ M G Sbjct: 409 GDTVGVRYIGKLQNGKQFDANKKG----KPFSFKAGKGQVIKGWDIGVIGMAIGGERRLT 464 Query: 363 IPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 IP A+GS L +P NST+ ++V+L+ + Sbjct: 465 IPAHLAYGSR----GLPGIPANSTLIFDVKLLEIK 495
>FKBA_ECOLI (P45523) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 270 Score = 55.1 bits (131), Expect = 1e-07 Identities = 45/132 (34%), Positives = 66/132 (50%) Frame = +3 Query: 138 ILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLD 317 ++ +V++ G+G E P D V V G L +G F G EP F+ D VI G Sbjct: 148 LVYQVVEAGKG-EAPKDSDTVVVNYKGTLIDGKEFDNSYTRG-EPLSFRLDG--VIPGWT 203 Query: 318 TTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKS 497 + +KKG IPPE A+G K + +PPNST+ ++VEL+ + ++ D K Sbjct: 204 EGLKNIKKGGKIKLVIPPELAYG----KAGVPGIPPNSTLVFDVELLDVKPAPKA-DAKP 258 Query: 498 NAEKIEAASKKK 533 A+ A S KK Sbjct: 259 EADAKAADSAKK 270
>FKBA_ECOL6 (P65764) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 270 Score = 55.1 bits (131), Expect = 1e-07 Identities = 45/132 (34%), Positives = 66/132 (50%) Frame = +3 Query: 138 ILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLD 317 ++ +V++ G+G E P D V V G L +G F G EP F+ D VI G Sbjct: 148 LVYQVVEAGKG-EAPKDSDTVVVNYKGTLIDGKEFDNSYTRG-EPLSFRLDG--VIPGWT 203 Query: 318 TTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKS 497 + +KKG IPPE A+G K + +PPNST+ ++VEL+ + ++ D K Sbjct: 204 EGLKNIKKGGKIKLVIPPELAYG----KAGVPGIPPNSTLVFDVELLDVKPAPKA-DAKP 258 Query: 498 NAEKIEAASKKK 533 A+ A S KK Sbjct: 259 EADAKAADSAKK 270
>FKBA_ECO57 (P65765) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 270 Score = 55.1 bits (131), Expect = 1e-07 Identities = 45/132 (34%), Positives = 66/132 (50%) Frame = +3 Query: 138 ILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLD 317 ++ +V++ G+G E P D V V G L +G F G EP F+ D VI G Sbjct: 148 LVYQVVEAGKG-EAPKDSDTVVVNYKGTLIDGKEFDNSYTRG-EPLSFRLDG--VIPGWT 203 Query: 318 TTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKS 497 + +KKG IPPE A+G K + +PPNST+ ++VEL+ + ++ D K Sbjct: 204 EGLKNIKKGGKIKLVIPPELAYG----KAGVPGIPPNSTLVFDVELLDVKPAPKA-DAKP 258 Query: 498 NAEKIEAASKKK 533 A+ A S KK Sbjct: 259 EADAKAADSAKK 270
>FKBP_YEAST (P20081) FK506-binding protein 1 (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rapamycin-binding protein) Length = 114 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/102 (32%), Positives = 50/102 (49%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 + G+G P G +V + G L+NG F G PF+ QVI+G D + Sbjct: 14 ISPGDGATFPKTGDLVTIHYTGTLENGQKFDSSVDRGS-PFQCNIGVGQVIKGWDVGIPK 72 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + GE A IP +A+G ++PPNST+ ++VEL+ Sbjct: 73 LSVGEKARLTIPGPYAYGPRGFP---GLIPPNSTLVFDVELL 111
>FKBP6_HUMAN (O75344) FK506-binding protein 6 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506-binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/140 (27%), Positives = 75/140 (53%) Frame = +3 Query: 45 VEGAVPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKL 224 +EG P +L+ E +S + + + GD + +LK V++EG G D +V+ V+ G L Sbjct: 11 LEGDDAPGQSLY---ERLSQRMLDISGD-RGVLKDVIREGAGDLVAPDASVL-VKYSGYL 65 Query: 225 DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKL 404 ++ + P K E+ + G++ +++M++GE+A P +A+G+ Sbjct: 66 EHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCP- 124 Query: 405 DLAVVPPNSTVFYEVELVSF 464 ++PPN+TV +E+EL+ F Sbjct: 125 --PLIPPNTTVLFEIELLDF 142
>FKBP3_ASHGO (Q756V1) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 418 Score = 54.3 bits (129), Expect = 2e-07 Identities = 37/93 (39%), Positives = 50/93 (53%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 GA V +R IGKL NG VF K + +PF FK +VI+G D V M G IP Sbjct: 332 GARVGMRYIGKLKNGKVFDK--NTSGKPFVFKLGHGEVIKGWDIGVAGMAVGGERRIVIP 389 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 +A+G K L +P NS + ++V+LVS + Sbjct: 390 AAYAYG----KQALPGIPANSELTFDVKLVSLK 418
>FKBP2_KLULA (Q6CUZ8) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 140 Score = 54.3 bits (129), Expect = 2e-07 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = +3 Query: 177 RPNDGAVVRVRLIGKL-DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVA 353 + + G VV V GKL D+G +F + G P +FK QVI G D ++ M GE Sbjct: 39 KASKGDVVSVHYTGKLRDSGEIFDSSYNRG-VPIQFKLGYSQVISGWDQGILGMCIGEGR 97 Query: 354 LARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 IP E +GS +V+PP++ + +E ELV ++E Sbjct: 98 TLHIPSELGYGSRGAG---SVIPPDADLIFETELVDIQRE 134
>FKBP_ASHGO (Q754K8) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 53.9 bits (128), Expect = 3e-07 Identities = 33/102 (32%), Positives = 49/102 (48%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 L G+G P G +V + G L+N F G PF+ QVI+G D + Sbjct: 14 LSPGDGKTFPKTGDLVTIHYTGTLENEQKFDSSVDRGS-PFQCNIGVGQVIKGWDVAIPK 72 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + GE A IP +A+G ++PPN+T+ +EVEL+ Sbjct: 73 LSVGEKARLTIPGAYAYGPRGFP---GLIPPNATLIFEVELL 111
>FKB1A_NEUCR (P20080) FK506-binding protein 1A (FKBP) (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) Length = 120 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/107 (33%), Positives = 51/107 (47%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 +V +EG+G G V V G L +G F G EP F + QVI+G D + Sbjct: 12 EVQQEGQGTRETRRGDNVDVHYKGVLTSGKKFDASYDRG-EPLNFTVGQGQVIKGWDEGL 70 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 + MK GE I P A+G+ ++P NST+ +E ELV + Sbjct: 71 LGMKIGEKRKLTIAPHLAYGNRAVG---GIIPANSTLIFETELVGIK 114
>FKBP_YARLI (Q6CF41) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 53.5 bits (127), Expect = 4e-07 Identities = 32/104 (30%), Positives = 51/104 (49%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 K L+ G+G P G V + +G L+NG F G EPF+ VI G D V Sbjct: 6 KQLQPGDGKTYPKKGDAVTIHYVGTLENGQKFDSSRDRG-EPFKTTIGVGDVIRGWDEGV 64 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + GE ++ I ++ +G ++PPN+T+ ++VEL+ Sbjct: 65 PKLSLGERSVLTISGDYGYGERGFP---GLIPPNATLVFDVELL 105
>FKB1A_MOUSE (P26883) FK506-binding protein 1A (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) Length = 107 Score = 53.5 bits (127), Expect = 4e-07 Identities = 30/107 (28%), Positives = 56/107 (52%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 + + G+G P G V G L++G F + ++PF+F +++VI G + V Sbjct: 5 ETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS-RDRNKPFKFTLGKQEVIRGWEEGV 63 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 M G+ A I ++A+G+T ++PP++T+ ++VEL+ E Sbjct: 64 AQMSVGQRAKLIISSDYAYGATGHP---GIIPPHATLVFDVELLKLE 107
>FKBP3_DEBHA (Q6BSE7) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 437 Score = 53.5 bits (127), Expect = 4e-07 Identities = 40/120 (33%), Positives = 61/120 (50%) Frame = +3 Query: 108 TVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKT 287 T TL+G ++ + K G+G + G V +R IGKL NG VF K + +PF F Sbjct: 328 TKTLLGG---VVTEDRKTGKG-QTAKSGNKVGIRYIGKLKNGKVFDK--NTSGKPFVFGL 381 Query: 288 DEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 + + I+G D V M G IPP+ +GS L +P NS + ++++LVS + Sbjct: 382 GKGECIKGFDLGVAGMAVGGERRVVIPPKMGYGSQA----LPGLPANSELTFDIKLVSIK 437
>FKBP3_CANGA (Q6FKH7) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 437 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/93 (38%), Positives = 49/93 (52%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G V +R IGKL NG VF K + +PF FK +VI+G D V M G IP Sbjct: 351 GDRVGMRYIGKLKNGKVFDK--NTSGKPFVFKLGRGEVIKGWDVGVAGMSVGSERRIIIP 408 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 +A+G K L +P NS + ++V+LVS + Sbjct: 409 APYAYG----KQALPGIPANSELTFDVKLVSIK 437
>FKBP_KLULA (Q6CX30) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 114 Score = 53.5 bits (127), Expect = 4e-07 Identities = 32/102 (31%), Positives = 49/102 (48%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 L G+ P G +V + G L+NG F G PF+ QVI+G D + Sbjct: 14 LSPGDSTNFPKPGDLVTIHYTGTLENGQKFDSSVDRGS-PFQCNIGVGQVIKGWDAAIPK 72 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + GE A IP +A+G ++PPN+T+ ++VEL+ Sbjct: 73 LSVGEKARLTIPGPYAYGPRGFP---GLIPPNATLVFDVELL 111
>FKBP4_ASPFU (Q4WMV5) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 489 Score = 52.8 bits (125), Expect = 6e-07 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVF--TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALAR 362 G V +R IGKL++G VF KKG +PF FK + +VI+G D + M G Sbjct: 403 GNTVAMRYIGKLEDGKVFDANKKG----KPFTFKLGKGEVIKGWDIGIAGMAVGGERRIT 458 Query: 363 IPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 IPP A+G K L +P NS + ++V+L+ + Sbjct: 459 IPPHLAYG----KKALPGIPANSKLIFDVKLLEIK 489
>FKBP4_ASPOR (Q2UN37) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 470 Score = 52.8 bits (125), Expect = 6e-07 Identities = 36/95 (37%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVF--TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALAR 362 G V +R IGKL++G VF KKG +PF FK + +VI+G D V M G Sbjct: 384 GNTVAMRYIGKLEDGKVFDANKKG----KPFTFKLGKGEVIKGWDIGVAGMAVGGERRIS 439 Query: 363 IPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 IPP A+G K L +P NS + ++V+L+ + Sbjct: 440 IPPHLAYG----KKALPGIPGNSKLIFDVKLLEIK 470
>FKBP2_CANGA (Q6FSC1) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 136 Score = 52.4 bits (124), Expect = 8e-07 Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = +3 Query: 189 GAVVRVRLIGKL-DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARI 365 G +V V G L +NG VF +EP +FK QVI G + + M GE I Sbjct: 45 GDMVSVHYTGSLAENGKVFDSSLRR-NEPIQFKLGAGQVIAGWEQGITGMCLGEKRTLHI 103 Query: 366 PPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEK 470 PPE A+GS V+PPN+ + ++VELV + Sbjct: 104 PPELAYGSRGAG---GVIPPNAVLDFDVELVDIAR 135
>FKBP3_YARLI (Q6C4C9) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 407 Score = 52.4 bits (124), Expect = 8e-07 Identities = 37/94 (39%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMK-KGEVALARI 365 G+ V VR +GKL NG VF +PF F + +VI G D V MK KGE + I Sbjct: 321 GSKVGVRYVGKLANGKVFDSNSK--GKPFYFSVGKGEVIRGWDIGVQGMKVKGERRII-I 377 Query: 366 PPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 PP A+G K L +PPNS + ++V++V+ + Sbjct: 378 PPGMAYG----KQKLPGIPPNSQLTFDVKVVNIK 407
>FKBP4_YEAST (Q06205) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 392 Score = 52.4 bits (124), Expect = 8e-07 Identities = 35/93 (37%), Positives = 50/93 (53%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G V +R +GKL NG VF K + +PF FK + +VI+G D V M G IP Sbjct: 306 GTRVGMRYVGKLKNGKVFDK--NTKGKPFVFKLGQGEVIKGWDIGVAGMAVGGERRIVIP 363 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 +A+G K L +P NS + ++V+LVS + Sbjct: 364 APYAYG----KQALPGIPANSELTFDVKLVSMK 392
>FKB12_VICFA (O04287) Peptidyl-prolyl isomerase FKBP12 (EC 5.2.1.8) (12 kDa| FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 112 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 3/108 (2%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIGKLDNGTV---FTKKGHEGDEPFEFKTDEEQVIEGL 314 K++++ G G P+ G V V G NG + F G PF FK + VI+G Sbjct: 5 KQIIRAGTG-PNPSRGQNVTVHCTGYGKNGDLSQKFWSTKDPGQNPFTFKIGQGSVIKGW 63 Query: 315 DTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 D V+ M+ GEVA R P++A+G+ + PNS + +E+E++ Sbjct: 64 DEGVLGMQLGEVARLRCSPDYAYGA--GGFPAWGIQPNSVLEFEIEVL 109
>FKB42_ARATH (Q9LDC0) 42 kDa peptidyl-prolyl isomerase (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Protein TWISTED DWARF1) (Protein ULTRACURVATA2) Length = 365 Score = 51.6 bits (122), Expect = 1e-06 Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 5/140 (3%) Frame = +3 Query: 129 DKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGT-VFTKKGHEGDEPFEFKTDEEQV- 302 D+++ K+++KEG G +P+ + + N F HE +P E +E+ Sbjct: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHE-QQPIELVLGKEKKE 105 Query: 303 IEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKES 482 + GL V +MK GE AL + E A+G E VPP + + YEVE++ F++ KE Sbjct: 106 LAGLAIGVASMKSGERALVHVGWELAYGK-EGNFSFPNVPPMADLLYEVEVIGFDETKEG 164 Query: 483 WDLKSN---AEKIEAASKKK 533 +S+ E+I AA ++K Sbjct: 165 -KARSDMTVEERIGAADRRK 183
>FKBP3_KLULA (Q6CWE8) FK506-binding protein 3 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 418 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/93 (37%), Positives = 49/93 (52%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G+ V +R IGKL NG VF K + +PF F +VI+G D V M G IP Sbjct: 332 GSKVGMRYIGKLKNGKVFDK--NTSGKPFVFNLGRGEVIKGWDIGVAGMAVGGERRIVIP 389 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 +A+G K L +P NS + ++V+LVS + Sbjct: 390 APYAYG----KQALPGIPANSELTFDVKLVSLK 418
>FKBP4_USTMA (Q4PIN7) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 375 Score = 51.6 bits (122), Expect = 1e-06 Identities = 32/93 (34%), Positives = 51/93 (54%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G V +R +GKL NG VF + +PF FK + +VI+G D V M+ G P Sbjct: 289 GQKVGMRYVGKLTNGKVFDQC--TSGKPFYFKLGKGEVIKGWDEGVKGMRVGAERRLTCP 346 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 P+ A+G+ + + +P NST+ ++V+LV + Sbjct: 347 PKLAYGNQK----IPGIPANSTLVFDVKLVEIK 375
>FKB12_ARATH (Q8LGG0) Peptidyl-prolyl isomerase FKBP12 (EC 5.2.1.8) (12 kDa| FK506-binding protein) (12 kDa FKBP) (FKBP-12) (Immunophilin FKBP12) (AtFKBP12) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 112 Score = 51.6 bits (122), Expect = 1e-06 Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 3/111 (2%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIGKLDNGTV---FTKKGHEGDEPFEFKTDEEQVIEGL 314 K+V++ G G +P G V V G +G + F EG +PF F+ + VI+G Sbjct: 5 KQVIRPGNG-PKPAPGQTVTVHCTGFGKDGDLSQKFWSTKDEGQKPFSFQIGKGAVIKGW 63 Query: 315 DTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 D V+ M+ GEVA R ++A+G+ + PNS + +E+E++S + Sbjct: 64 DEGVIGMQIGEVARLRCSSDYAYGA--GGFPAWGIQPNSVLDFEIEVLSVQ 112
>FKBP_CRYNV (O94746) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 51.2 bits (121), Expect = 2e-06 Identities = 33/102 (32%), Positives = 51/102 (50%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 + G+G P G V + +G L +G+ F G PF + + QVI G D V Sbjct: 8 ISAGDGKTFPQPGDNVTIHYVGTLLDGSKFDSSRDRGT-PFVCRIGQGQVIRGWDEGVPQ 66 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + G+ A P++A+G+ V+PPNST+ +EVEL+ Sbjct: 67 LSVGQKANLICTPDYAYGARGFP---PVIPPNSTLKFEVELL 105
>FKBP_CRYNE (Q5KMG3) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 51.2 bits (121), Expect = 2e-06 Identities = 33/102 (32%), Positives = 51/102 (50%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 + G+G P G V + +G L +G+ F G PF + + QVI G D V Sbjct: 8 ISAGDGKTFPQPGDSVTIHYVGTLLDGSKFDSSRDRGT-PFVCRIGQGQVIRGWDEGVPQ 66 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + G+ A P++A+G+ V+PPNST+ +EVEL+ Sbjct: 67 LSIGQKANLICTPDYAYGARGFP---PVIPPNSTLKFEVELL 105
>FKBP2_NEUCR (O60046) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-21) (NcFKBP22) Length = 217 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 2/119 (1%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G + V G L + ++ PF FK QVI+G D +V M GE +P Sbjct: 41 GDKINVHYRGTLQSNGQQFDASYDRGTPFSFKLGGGQVIKGWDEGLVDMCIGEKRTLTVP 100 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE--KEKESWDLKSNAEKIEAASKKKDE 539 P + +G + + +P ST+ +E EL+ + + ES K AEK E A+ +E Sbjct: 101 PSYGYG----QRSIGPIPAGSTLIFETELIGIDGVPKPESIVYKQAAEKAEEAASAVEE 155
>FKB22_ARATH (Q38936) FK506-binding protein 2-2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-2) Length = 163 Score = 51.2 bits (121), Expect = 2e-06 Identities = 30/95 (31%), Positives = 49/95 (51%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G ++V GKL +GTVF GD PFEFK QVI+G D ++ GE +IP Sbjct: 52 GDTIKVHYRGKLTDGTVFDSSFERGD-PFEFKLGSGQVIKGWDQGLLGACVGEKRKLKIP 110 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 + +G + +P +T+ ++ EL++ ++ Sbjct: 111 AKLGYGEQGSP---PTIPGGATLIFDTELIAVNEK 142
>FKBP4_EMENI (P0C1B0) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 478 Score = 50.8 bits (120), Expect = 2e-06 Identities = 35/95 (36%), Positives = 50/95 (52%), Gaps = 2/95 (2%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVF--TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALAR 362 G V +R IGKL+NG VF KKG +PF FK + +VI+G D V M G Sbjct: 392 GNTVAMRYIGKLENGKVFDSNKKG----KPFTFKLGKGEVIKGWDIGVAGMAVGGERRIT 447 Query: 363 IPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 IP A+G K + +P NS + ++V+L+ + Sbjct: 448 IPSHLAYG----KKGVPGIPGNSKLIFDVKLLEIK 478
>FKBY_HAEIN (P44760) Probable FKBP-type peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 241 Score = 50.8 bits (120), Expect = 2e-06 Identities = 37/114 (32%), Positives = 56/114 (49%) Frame = +3 Query: 138 ILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLD 317 ++ K+ G+G + V+V GKL NG VF G +P EF+ D QVI+G Sbjct: 134 LMYKIESAGKG-DTIKSTDTVKVHYTGKLPNGKVFDSSVERG-QPVEFQLD--QVIKGWT 189 Query: 318 TTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKE 479 + +KKG I PE +G A +PPNST+ ++VE++ + E Sbjct: 190 EGLQLVKKGGKIQFVIAPELGYGEQGAG---ASIPPNSTLIFDVEVLDVNPKSE 240
>FKBPH_SCHPO (Q10175) Probable peptidyl-prolyl cis-trans isomerase C27F1.06c (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 362 Score = 50.1 bits (118), Expect = 4e-06 Identities = 32/88 (36%), Positives = 48/88 (54%) Frame = +3 Query: 198 VRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEH 377 V +R IG+L NG VF K + +PF F E+VI+G D +V M+ G IP Sbjct: 279 VSMRYIGRLTNGKVFDK--NITGKPFTFNLGLEEVIKGWDVGIVGMQVGGERTIHIPAAM 336 Query: 378 AFGSTETKLDLAVVPPNSTVFYEVELVS 461 A+GS L +P NS + ++V+L++ Sbjct: 337 AYGSKR----LPGIPANSDLVFDVKLLA 360
>MIP_COXBU (P51752) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (Macrophage infectivity potentiator) Length = 230 Score = 49.3 bits (116), Expect = 7e-06 Identities = 35/109 (32%), Positives = 54/109 (49%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 KVL+ G+G + P V V G+L NGTVF G +P F + VI+G + Sbjct: 129 KVLQAGQG-QSPTLNDEVTVNYEGRLINGTVFDSSYKRG-QPATFPL--KSVIKGWQEAL 184 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 MK G + +PP+ A+G V+ PN + ++V L+S +K+ Sbjct: 185 TRMKPGAIWEIYVPPQLAYGEQGAP---GVIGPNEALIFKVNLISVKKK 230
>FKBP2_MOUSE (P45878) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 140 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/97 (31%), Positives = 49/97 (50%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G V+ + GKL++GT F + ++PF F QVI+G D ++ M +GE IP Sbjct: 47 GDVLHMHYTGKLEDGTEFDSSLPQ-NQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIP 105 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKE 479 E +G +P +T+ +EVEL+ E+ E Sbjct: 106 SELGYGERGAP---PKIPGGATLVFEVELLKIERRSE 139
>FKBP3_ARATH (Q9SCY2) FKBP-type peptidyl-prolyl cis-trans isomerase 3,| chloroplast precursor (EC 5.2.1.8) (PPIase) (Rotamase) (AtFKBP13) (FK506-binding protein 1) Length = 208 Score = 47.8 bits (112), Expect = 2e-05 Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 8/98 (8%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVV------TMKKGEV 350 G +++ +GKL+NG VF + G +P F+ +VI+G D ++ M G Sbjct: 109 GQLIKAHYVGKLENGKVFDSSYNRG-KPLTFRIGVGEVIKGWDQGILGSDGIPPMLTGGK 167 Query: 351 ALARIPPEHAFG--STETKLDLAVVPPNSTVFYEVELV 458 RIPPE A+G K ++PP S + +++E + Sbjct: 168 RTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYI 205
>FKBP2_HUMAN (P26885) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (13 kDa FKBP) (FKBP-13) Length = 142 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/97 (31%), Positives = 49/97 (50%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G V+ + GKL++GT F + ++PF F QVI+G D ++ M +GE IP Sbjct: 49 GDVLHMHYTGKLEDGTEFDSSLPQ-NQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIP 107 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKE 479 E +G +P +T+ +EVEL+ E+ E Sbjct: 108 SELGYGERGAP---PKIPGGATLVFEVELLKIERRTE 141
>FKB21_ARATH (Q38935) FK506-binding protein 2-1 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15-1) Length = 153 Score = 47.4 bits (111), Expect = 3e-05 Identities = 34/106 (32%), Positives = 51/106 (48%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G ++V GKL +GTVF GD P EF+ QVI G D ++ GE +IP Sbjct: 52 GDKIKVHYRGKLTDGTVFDSSFERGD-PIEFELGTGQVIPGWDQGLLGACVGEKRKLKIP 110 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAE 506 + +G + +P +T+ ++ ELV+ E S + KS E Sbjct: 111 SKLGYGDNGSP---PKIPGGATLIFDTELVAVNGEPSS-EAKSKNE 152
>FKB1A_EMENI (Q6KBA8) FK506-binding protein 1A (EC 5.2.1.8) (FKBP) (FkbA)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 108 Score = 47.4 bits (111), Expect = 3e-05 Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTD--EEQVIEGLDTTV 326 + G+G P G V + G L +G+ F D P F T +VI+G D V Sbjct: 8 ISPGDGKNFPKPGDTVSIHYTGTLADGSKFDSSR---DRPGTFVTQIGVGRVIKGWDEGV 64 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + + GE A P++A+G+ V+PPN+T+ +EVEL+ Sbjct: 65 LQLSVGEKAKLICTPDYAYGARGFP---PVIPPNATLTFEVELL 105
>FKB15_VICFA (Q41649) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (15 kDa FKBP) (FKBP-15) Length = 151 Score = 46.6 bits (109), Expect = 4e-05 Identities = 31/106 (29%), Positives = 53/106 (50%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G V+V GKL +GTVF E + P +F+ QVI+G D ++ M GE +IP Sbjct: 49 GDKVKVHYRGKLTDGTVFDSS-FERNSPIDFELGGGQVIKGWDQGLLGMCLGEKRKLKIP 107 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAE 506 + +G + +P +T+ ++ ELV + S + +++E Sbjct: 108 AKLGYGEQGSP---PTIPGGATLIFDTELVGVNDKSLSEEKSTSSE 150
>FKBP9_MOUSE (Q9Z247) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP65RS) Length = 570 Score = 46.2 bits (108), Expect = 6e-05 Identities = 30/92 (32%), Positives = 44/92 (47%) Frame = +3 Query: 183 NDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALAR 362 + G VR +G +G F ++ D F + Q+I G+D +V M E L Sbjct: 52 HSGDFVRYHYVGTFLDGQKFDSS-YDRDSTFNVFVGKGQLIAGMDQALVGMCVNERRLVT 110 Query: 363 IPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 IPP A+GS V+PPNS + ++V LV Sbjct: 111 IPPNLAYGSEGVS---GVIPPNSVLHFDVLLV 139 Score = 45.8 bits (107), Expect = 8e-05 Identities = 40/167 (23%), Positives = 72/167 (43%), Gaps = 3/167 (1%) Frame = +3 Query: 45 VEGAVPPNSTLHIDLELVS-WKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGK 221 V G +PPNS LH D+ LV W + +D+ ++ K VR G Sbjct: 122 VSGVIPPNSVLHFDVLLVDIWNS-----EDQVHIQTYFKPPSCPRTIQVSDFVRYHYNGT 176 Query: 222 LDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETK 401 +GT+F H + ++ +I G+D ++ M GE + +PP A+G Sbjct: 177 FLDGTLF-DSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITVPPFLAYGEEGDG 235 Query: 402 LDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNA--EKIEAASKKKD 536 D +P +++ ++V L+ K++ +++ E E S+ D Sbjct: 236 KD---IPGQASLVFDVALLDLHNPKDTISIENKVVPENCERRSQSGD 279
>FKBP8_MOUSE (O35465) 38 kDa FK506-binding protein homolog (FKBPR38)| (FK506-binding protein 8) (muFKBP38) Length = 355 Score = 46.2 bits (108), Expect = 6e-05 Identities = 45/175 (25%), Positives = 78/175 (44%), Gaps = 1/175 (0%) Frame = +3 Query: 15 LASKXRPASEVEGAVPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGA 194 LA + A+E E A P +D+ +G+ +K ++ +G RP G Sbjct: 15 LAREFLAATEPEPAPAPAPEEWLDI----------LGNGLLRMKTLVPCPKGSSRPLKGQ 64 Query: 195 VVRVRLIGKLDNGTVFTKKGHEGDEP-FEFKTDEEQVIEGLDTTVVTMKKGEVALARIPP 371 VV V L L+NGT +EP F + VI+ LD +V M GE A+ Sbjct: 65 VVTVHLQMSLENGT------RVQEEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADS 118 Query: 372 EHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKD 536 ++ +G +PP++ + EV L + E + ++ S E++ A++K++ Sbjct: 119 KYCYGPQGRS---PYIPPHAALCLEVTLKTAE-DGPDLEMLSGQERVALANRKRE 169
>FKBA_BUCBP (Q89A61) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 251 Score = 46.2 bits (108), Expect = 6e-05 Identities = 34/108 (31%), Positives = 53/108 (49%) Frame = +3 Query: 150 VLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVV 329 + K+G G + +D V+ V G L NG F G +P F D VI G + Sbjct: 152 IKKKGSG-KFLHDSDVITVHYKGSLINGNEFDNSYKRG-QPLSFSLDS--VIPGWIEGLK 207 Query: 330 TMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKE 473 +KKG + IPP+ A+G T + +P NST+ +E+EL+ + + Sbjct: 208 YIKKGGLIKLVIPPKLAYGET----GVPGIPGNSTLIFEIELIDIQSK 251
>FKB1B_ASPFU (Q4W9R2) FK506-binding protein 1B (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 120 Score = 46.2 bits (108), Expect = 6e-05 Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 6/114 (5%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIGKL-DNGTVFTKKGHEGDE-----PFEFKTDEEQVI 305 K+ L+ G G + P G V + G L D KG E D P + VI Sbjct: 5 KQTLRMGNGKDHPQPGDPVELNYTGYLYDESNPDHHKGKEFDSSKRRGPLKATIGAGDVI 64 Query: 306 EGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 G D V M GE A+ + E+A+G K ++PPN+++ +EVEL+ + Sbjct: 65 RGWDEGVRQMSLGEKAILTMSGEYAYGE---KGFPGLIPPNASLVFEVELLKIK 115
>FKBP_CANAL (P28870) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 124 Score = 46.2 bits (108), Expect = 6e-05 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 11/115 (9%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 ++++EG+ G V + GKL NG F G +PF QVI+G D ++ Sbjct: 9 EIVQEGDNTTFAKPGDTVTIHYDGKLTNGKEFDSSRKRG-KPFTCTVGVGQVIKGWDISL 67 Query: 327 VT-----------MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + KG A+ IPP A+G ++ PN T+ +EVEL+ Sbjct: 68 TNNYGKGGANLPKISKGTKAILTIPPNLAYGPRGIP---PIIGPNETLVFEVELL 119
>FKBP9_RAT (Q66H94) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 570 Score = 45.8 bits (107), Expect = 8e-05 Identities = 41/167 (24%), Positives = 72/167 (43%), Gaps = 3/167 (1%) Frame = +3 Query: 45 VEGAVPPNSTLHIDLELVS-WKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGK 221 V G +PPNS LH D+ LV W + +D+ ++ K VR G Sbjct: 122 VSGVIPPNSVLHFDVLLVDIWNS-----EDQVQIQTYFKPPSCPRTIQVSDFVRYHYNGT 176 Query: 222 LDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETK 401 +GT+F H + ++ +I G+D ++ M GE + IPP A+G Sbjct: 177 FLDGTLF-DSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEEGDG 235 Query: 402 LDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNA--EKIEAASKKKD 536 D +P +++ ++V L+ K++ +++ E E S+ D Sbjct: 236 KD---IPGQASLVFDVALLDLHNPKDTISVENKVVPESCERRSQSGD 279 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/103 (28%), Positives = 47/103 (45%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G VR +G +G F ++ D F + Q+I G+D +V M E IP Sbjct: 54 GDFVRYHYVGTFLDGQKFDSS-YDRDSTFSVFVGKGQLIAGMDQALVGMCVNERRFVTIP 112 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKS 497 P A+GS V+PPNS + ++V LV ++ +++ Sbjct: 113 PNLAYGSEGVS---GVIPPNSVLHFDVLLVDIWNSEDQVQIQT 152
>FKB10_HUMAN (Q96AY3) FK506-binding protein 10 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65) Length = 582 Score = 45.8 bits (107), Expect = 8e-05 Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 1/150 (0%) Frame = +3 Query: 51 GAVPPNSTLHIDLELVS-WKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLD 227 G +PP++TL+ D+ L+ W +D + +L+ DG VR G L Sbjct: 132 GLIPPDATLYFDVVLLDVWNK-----EDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLL 186 Query: 228 NGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLD 407 +GT F +G ++ +I+G+D ++ M GE IPP A+G K Sbjct: 187 DGTSFDTSYSKGGT-YDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGE---KGY 242 Query: 408 LAVVPPNSTVFYEVELVSFEKEKESWDLKS 497 V+PP +++ + V L+ K++ L++ Sbjct: 243 GTVIPPQASLVFHVLLIDVHNPKDAVQLET 272 Score = 40.8 bits (94), Expect = 0.002 Identities = 30/82 (36%), Positives = 41/82 (50%) Frame = +3 Query: 222 LDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETK 401 LD +FT H+ P E +VIEGLDT + M GE +PP A G + + Sbjct: 411 LDGTQLFTS--HDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR 468 Query: 402 LDLAVVPPNSTVFYEVELVSFE 467 VP ++ + +EVELVS E Sbjct: 469 ----GVPGSAVLLFEVELVSRE 486 Score = 31.6 bits (70), Expect = 1.5 Identities = 23/117 (19%), Positives = 49/117 (41%) Frame = +3 Query: 177 RPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVAL 356 R G +R G L +GT+F + + + + +I G+D + GE Sbjct: 282 RAGAGDFMRYHYNGSLMDGTLFDSS-YSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRR 340 Query: 357 ARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASK 527 IPP A+G T +P ++ + + V ++ F + ++++ + E ++ Sbjct: 341 ITIPPHLAYGENGTG---DKIPGSAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNE 394
>FKBP9_HUMAN (O95302) FK506-binding protein 9 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 570 Score = 45.4 bits (106), Expect = 1e-04 Identities = 41/167 (24%), Positives = 71/167 (42%), Gaps = 3/167 (1%) Frame = +3 Query: 45 VEGAVPPNSTLHIDLELVS-WKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGK 221 V G +PPNS LH D+ L+ W + +D+ + K VR G Sbjct: 122 VSGVIPPNSVLHFDVLLMDIWNS-----EDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGT 176 Query: 222 LDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETK 401 +GT+F H + ++ +I G+D ++ M GE + IPP A+G Sbjct: 177 FLDGTLF-DSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDG 235 Query: 402 LDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNA--EKIEAASKKKD 536 D +P +++ ++V L+ K+S +++ E E S+ D Sbjct: 236 KD---IPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGD 279 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/90 (30%), Positives = 44/90 (48%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G VR +G +G F ++ D F + Q+I G+D +V M E +IP Sbjct: 54 GDFVRYHYVGTFPDGQKFDSS-YDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIP 112 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 P+ A+G+ V+PPNS + ++V L+ Sbjct: 113 PKLAYGNEGVS---GVIPPNSVLHFDVLLM 139
>FKBP_NEIMA (P56989) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/102 (33%), Positives = 49/102 (48%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 L+EG G E G + V G L+NGT F + +P QVI+G D Sbjct: 9 LQEGFGKEAVK-GKEITVHYTGWLENGTKFDSS-LDRRQPLTITLGVGQVIKGWDEGFGG 66 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 MK+G IP E +G+ V+PP++T+ +EVEL+ Sbjct: 67 MKEGGKRKLTIPSEMGYGARGAG---GVIPPHATLIFEVELL 105
>FKBP4_CRYNE (Q5KIJ5) FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl| cis-trans isomerase) (PPIase) (Rotamase) Length = 405 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/144 (29%), Positives = 64/144 (44%) Frame = +3 Query: 30 RPASEVEGAVPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVR 209 +PA++ E P TL L + K IGD V K G+ + +R Sbjct: 284 KPATKKEAKAPQKKTLPSGLIIEDIK----IGDGP-----VAKTGKR---------LGMR 325 Query: 210 LIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGS 389 IGKL NG F + +PF F + +VI G D + M G IP A+G+ Sbjct: 326 YIGKLTNGKQFD--ANTSGKPFSFVLGKGEVIRGWDEGLAGMAVGGERRLTIPAALAYGN 383 Query: 390 TETKLDLAVVPPNSTVFYEVELVS 461 + + +P NST+ ++V+LVS Sbjct: 384 QK----IPGIPKNSTLKFDVKLVS 403
>FKBP_NEIMB (P0A0W2) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/102 (33%), Positives = 49/102 (48%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 L+EG G E G + V G L+NGT F + +P QVI+G D Sbjct: 9 LQEGFGKEAVK-GKEITVHYTGWLENGTKFDSS-LDRRQPLTITLGVGQVIKGWDEGFGG 66 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 MK+G IP E +G+ V+PP++T+ +EVEL+ Sbjct: 67 MKEGGKRKLTIPSEMGYGAHGAG---GVIPPHATLIFEVELL 105
>FKBB_SHIFL (P0A9L4) FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) (FKBP22) Length = 205 Score = 44.7 bits (104), Expect = 2e-04 Identities = 39/104 (37%), Positives = 50/104 (48%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 +V+ +GEG P VRV GKL +GTVF G EP EF + VI G + Sbjct: 106 RVINQGEG-AIPARTDRVRVHYTGKLIDGTVFDSSVARG-EPAEFPVNG--VIPGWIEAL 161 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 M G IP E A+G A +PP ST+ +EVEL+ Sbjct: 162 TLMPVGSKWELTIPQELAYGERGAG---ASIPPFSTLVFEVELL 202
>FKBB_ECOLI (P0A9L3) FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) (FKBP22) Length = 205 Score = 44.7 bits (104), Expect = 2e-04 Identities = 39/104 (37%), Positives = 50/104 (48%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 +V+ +GEG P VRV GKL +GTVF G EP EF + VI G + Sbjct: 106 RVINQGEG-AIPARTDRVRVHYTGKLIDGTVFDSSVARG-EPAEFPVNG--VIPGWIEAL 161 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 M G IP E A+G A +PP ST+ +EVEL+ Sbjct: 162 TLMPVGSKWELTIPQELAYGERGAG---ASIPPFSTLVFEVELL 202
>FKBP_METTL (O52980) FKBP-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)| (PPIase) (Rotamase) (MtFK) Length = 154 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 12/84 (14%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGD------------EPFEFKTDEEQVIEGLDTTVVT 332 G ++V IGKL++G VF E EP EF E Q+I+G + V+ Sbjct: 8 GVKIKVDYIGKLESGDVFDTSIEEVAKEAGIYAPDREYEPLEFVVGEGQLIQGFEEAVLD 67 Query: 333 MKKGEVALARIPPEHAFGSTETKL 404 M+ G+ +IP E A+G+ L Sbjct: 68 MEVGDEKTVKIPAEKAYGNRNEML 91
>FKBP2_ASPOR (Q2UPT7) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 134 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/133 (27%), Positives = 59/133 (44%) Frame = +3 Query: 69 STLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTK 248 STL + L +S T +G +K E E + G V++ G L + Sbjct: 7 STLLVSLATLS--TAAELGIEKT------HEVECTRKTVKGDTVQMHYKGTLQSDGSEFD 58 Query: 249 KGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPN 428 ++ + P +FK VI+G D ++ M GE IPPE+ +GS + +P Sbjct: 59 SSYKRNSPLKFKVGSGMVIKGWDEGLLDMCIGEKRTLTIPPEYGYGSR----GVGPIPGG 114 Query: 429 STVFYEVELVSFE 467 +T+ +E ELV + Sbjct: 115 ATLIFETELVGID 127
>FKBP_GIBZE (Q4HZB8) FK506-binding protein 1 (EC 5.2.1.8) (FKBP) (FkbA)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 111 Score = 43.9 bits (102), Expect = 3e-04 Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 5/109 (4%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIGKLDN-----GTVFTKKGHEGDEPFEFKTDEEQVIE 308 K ++ +G G P G V + G L G F GD F QVI+ Sbjct: 5 KTIITQGSG-PSPQVGQKVTMEYTGWLQKEDGTKGDQFDTSVGRGD--FVVNIGVGQVIK 61 Query: 309 GLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVEL 455 G D V MK GE A I P++ +G +PPNST+ ++VEL Sbjct: 62 GWDEGVTQMKLGEKATLHISPDYGYGPRGFP---GAIPPNSTLIFDVEL 107
>FKB39_DROME (P54397) 39 kDa FK506-binding nuclear protein (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 357 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/107 (31%), Positives = 52/107 (48%) Frame = +3 Query: 135 RILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGL 314 +I+ +V+ +GE G V V IG+L + +G +PF+F +VI+G Sbjct: 254 KIVDQVVGKGE---EAKQGKRVSVYYIGRLQSNNKTFDSLLKG-KPFKFALGGGEVIKGW 309 Query: 315 DTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVEL 455 D V MK G + PP A+G+ + PNST+ +EVEL Sbjct: 310 DVGVAGMKVGGKRVITCPPHMAYGARGAP---PKIGPNSTLVFEVEL 353
>FKBP2_GIBZE (Q4IN00) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 195 Score = 43.1 bits (100), Expect = 5e-04 Identities = 27/81 (33%), Positives = 38/81 (46%) Frame = +3 Query: 225 DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKL 404 D+G F G P FK QVI+G D ++ M GE + IPPE +G Sbjct: 52 DSGKQFDASYDRGT-PLSFKVGAGQVIKGWDEGLLDMCIGEKRVLTIPPEFGYGQRA--- 107 Query: 405 DLAVVPPNSTVFYEVELVSFE 467 + +P ST+ +E ELV + Sbjct: 108 -IGPIPAGSTLVFETELVGID 127
>FKBP2_EMENI (Q5ATN7) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 135 Score = 43.1 bits (100), Expect = 5e-04 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Frame = +3 Query: 189 GAVVRVRLIGKL-DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARI 365 G V++ G L ++G+ F G PF+FK +VI+G D ++ M GE I Sbjct: 40 GDTVKMHYRGTLAEDGSQFDASYDRGT-PFKFKLGAGRVIKGWDEGLLDMCVGEKRTLTI 98 Query: 366 PPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 PPE+ +G + +P +T+ ++ EL+ E Sbjct: 99 PPEYGYGDR----GIGPIPGGATLIFQTELLEIE 128
>FKBP2_DEBHA (Q6BP84) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 135 Score = 43.1 bits (100), Expect = 5e-04 Identities = 29/90 (32%), Positives = 43/90 (47%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G ++ V GKL++GTVF G +P F+ QVI+G D + M GE IP Sbjct: 40 GDLISVHYEGKLEDGTVFDSSYSRG-QPISFQLGIGQVIQGWDQGLTRMCIGEKRKLTIP 98 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 A+G + +P +T+ + ELV Sbjct: 99 SHLAYGDR----GVGPIPAKATLVFVAELV 124
>FKBP4_SPOFR (Q26486) 46 kDa FK506-binding nuclear protein (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 412 Score = 42.7 bits (99), Expect = 6e-04 Identities = 30/89 (33%), Positives = 43/89 (48%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G VV V G+L +G F+F+ ++VI G D + MK G P Sbjct: 324 GKVVMVYYEGRLKQNNKMFDNCVKGPG-FKFRLGSKEVISGWDVGIAGMKVGGKRKIVCP 382 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVEL 455 P A+G+ K V+PPNST+ +EV+L Sbjct: 383 PAMAYGA---KGSPPVIPPNSTLVFEVDL 408
>MIP_TRYCR (Q09734) Macrophage infectivity potentiator precursor| (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 196 Score = 42.7 bits (99), Expect = 6e-04 Identities = 35/129 (27%), Positives = 61/129 (47%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 + G G P V G+L +GTVF G +P F+ +E VI+G + Sbjct: 73 IARGSGKRAPAIDDKCEVHYTGRLRDGTVFDSSRERG-KPTTFRPNE--VIKGWTEALQL 129 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKI 512 M++G+ IP + A+G T ++PP S + ++VEL+S + + AE++ Sbjct: 130 MREGDRWRLFIPYDLAYGVTGGG---GMIPPYSPLEFDVELISIKDGGKG----RTAEEV 182 Query: 513 EAASKKKDE 539 + +K +E Sbjct: 183 DEILRKAEE 191
>FKBP2_YEAST (P32472) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-13) (FKBP-15) Length = 135 Score = 42.7 bits (99), Expect = 6e-04 Identities = 31/91 (34%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Frame = +3 Query: 189 GAVVRVRLIGKL-DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARI 365 G V+V G L ++GTVF G P F+ +VI+G D V M GE +I Sbjct: 43 GDKVKVHYTGSLLESGTVFDSSYSRGS-PIAFELGVGRVIKGWDQGVAGMCVGEKRKLQI 101 Query: 366 PPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 P A+G V+PP++ + ++VELV Sbjct: 102 PSSLAYGERGVP---GVIPPSADLVFDVELV 129
>FKBP2_ASPFU (Q4WHX4) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 134 Score = 42.4 bits (98), Expect = 8e-04 Identities = 22/68 (32%), Positives = 37/68 (54%) Frame = +3 Query: 264 DEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFY 443 ++P +FK +VI+G D ++ M GE IPPE+ +G + + +P +T+ + Sbjct: 64 NQPLKFKLGAGRVIKGWDEGLLDMCVGEKRTLTIPPEYGYG----ERGIGPIPGGATLIF 119 Query: 444 EVELVSFE 467 E ELV E Sbjct: 120 ETELVQIE 127
>FKBP8_HUMAN (Q14318) 38 kDa FK506-binding protein homolog (FKBPR38)| (FK506-binding protein 8) Length = 355 Score = 42.0 bits (97), Expect = 0.001 Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Frame = +3 Query: 144 KKVLKEGE-GYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEP-FEFKTDEEQVIEGLD 317 KK L G G RP G VV V L L+NGT +EP F + VI+ LD Sbjct: 47 KKTLVPGPPGSSRPVKGQVVTVHLQTSLENGT------RVQEEPELVFTLGDCDVIQALD 100 Query: 318 TTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKS 497 +V M GE A+ ++ +G +PP++ + EV L + + ++ + Sbjct: 101 LSVPLMDVGETAMVTADSKYCYGPQGRS---PYIPPHAALCLEVTLKT-AVDGPDLEMLT 156 Query: 498 NAEKIEAASKKKD 536 E++ A++K++ Sbjct: 157 GQERVALANRKRE 169
>FKBP7_MOUSE (O54998) FK506-binding protein 7 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-23) Length = 218 Score = 41.2 bits (95), Expect = 0.002 Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 3/89 (3%) Frame = +3 Query: 225 DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGS---TE 395 D + + + P F VI+GLD ++ M GE IPP A+G E Sbjct: 63 DGSKFYCSRTQDEGHPKWFVLGVGHVIKGLDIAMMDMCPGEKRKVIIPPSFAYGKEGYAE 122 Query: 396 TKLDLAVVPPNSTVFYEVELVSFEKEKES 482 K +PPN+T+ +E+EL + K S Sbjct: 123 GK-----IPPNATLMFEIELYAVTKGPRS 146
>FKBP7_PONPY (Q5RET2) FK506-binding protein 7 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 222 Score = 40.8 bits (94), Expect = 0.002 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 3/115 (2%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 K K+G+ DG + + D + + P F QVI+GLD + Sbjct: 48 KTSKKGDLLNAHYDGYLAK-------DGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAM 100 Query: 327 VTMKKGEVALARIPPEHAFGS---TETKLDLAVVPPNSTVFYEVELVSFEKEKES 482 M GE IPP A+G E K +PP++T+ +E+EL + K S Sbjct: 101 TDMCPGEKRKVVIPPSFAYGKEGYAEGK-----IPPDATLIFEIELYAVTKGPRS 150
>FKBP_ASPOR (Q2U316) FK506-binding protein 1 (EC 5.2.1.8) (FKBP)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rapamycin-binding protein) Length = 116 Score = 40.8 bits (94), Expect = 0.002 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 9/114 (7%) Frame = +3 Query: 144 KKVLKEGEGYERPNDGAVVRVRLIG---------KLDNGTVFTKKGHEGDEPFEFKTDEE 296 +K++ G G P G V + G K G F G P + Sbjct: 5 RKIITRGSG-PSPASGDKVSIHYTGWIYDPKKANKGFQGKQFDSSRSPGRGPLVVNIGQG 63 Query: 297 QVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 +VI+G D V+ M GE + I P++ +G +P NST+ +EVEL+ Sbjct: 64 KVIKGWDEGVMQMSLGEKSTLTITPDYGYGDKAA----GKIPANSTLIFEVELL 113
>FKBP_NEIMC (P0A0W3) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 109 Score = 40.4 bits (93), Expect = 0.003 Identities = 32/102 (31%), Positives = 48/102 (47%) Frame = +3 Query: 153 LKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVT 332 L+E G E G + V G L++GT F + +P QVI+G D Sbjct: 9 LQESFGKEAVK-GKEITVHYTGWLEDGTKFDSS-LDRRQPLTITLGVGQVIKGWDEGFGG 66 Query: 333 MKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 MK+G IP E +G+ V+PP++T+ +EVEL+ Sbjct: 67 MKEGGKRKLTIPSEMGYGAHGAG---GVIPPHATLIFEVELL 105
>FKBP2_ARATH (O22870) Probable FKBP-type peptidyl-prolyl cis-trans isomerase 2,| chloroplast precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 223 Score = 40.0 bits (92), Expect = 0.004 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = +3 Query: 105 KTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFK 284 + V ++ + + K +K G G P G V + + +G +F +G P+ F+ Sbjct: 97 ENVPMVTTESGLQYKDIKVGRG-PSPPVGFQVAANYVAMVPSGQIFDSSLEKG-LPYLFR 154 Query: 285 TDEEQVIEGLDTTVVTMKKGEVALARIPPEHAF-GSTETKLDLAVVPPNSTVFYEVEL 455 QVI+GLD +++MK G IP AF + V PNS V ++V L Sbjct: 155 VGSGQVIKGLDEGILSMKAGGKRRLYIPGPLAFPKGLVSAPGRPRVAPNSPVIFDVSL 212
>MIP_LEGPH (Q5ZXE0) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 233 Score = 39.7 bits (91), Expect = 0.005 Identities = 31/108 (28%), Positives = 47/108 (43%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 KV+ G G +P V V G+L +GTVF G +P F+ QVI G + Sbjct: 131 KVINSGNGV-KPGKSDTVTVEYTGRLIDGTVFDSTEKTG-KPATFQV--SQVIPGWTEAL 186 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEK 470 M G +P A+G + PN T+ +++ L+S +K Sbjct: 187 QLMPAGSTWEIYVPSGLAYGPRSVG---GPIGPNETLIFKIHLISVKK 231
>MIP_LEGPN (P69059) Outer membrane protein MIP precursor (Macrophage| infectivity potentiator) (Peptidyl-prolyl cis-trans isomerase) (EC 5.2.1.8) (PPIase) (Rotamase) Length = 233 Score = 39.3 bits (90), Expect = 0.007 Identities = 31/108 (28%), Positives = 47/108 (43%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 KV+ G G +P V V G+L +GTVF G +P F+ QVI G + Sbjct: 131 KVINAGNGV-KPGKSDTVTVEYTGRLIDGTVFDSTEKTG-KPATFQV--SQVIPGWTEAL 186 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEK 470 M G +P A+G + PN T+ +++ L+S +K Sbjct: 187 QLMPAGSTWEIYVPSGLAYGPRSVG---GPIGPNETLIFKIHLISVKK 231
>FKBP2_CRYNE (Q5KGT9) FK506-binding protein 2 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 141 Score = 39.3 bits (90), Expect = 0.007 Identities = 24/68 (35%), Positives = 35/68 (51%) Frame = +3 Query: 264 DEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFY 443 + PFEF QVI+G D ++ M E IP A+G + V+PP ST+ + Sbjct: 70 NRPFEFTLGAGQVIKGWDQGLLDMCISEKRKLTIPSHLAYGE---RGHPPVIPPQSTLVF 126 Query: 444 EVELVSFE 467 EVEL+ + Sbjct: 127 EVELLGIK 134
>FKBA_BUCAP (Q8K943) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 252 Score = 38.9 bits (89), Expect = 0.009 Identities = 31/104 (29%), Positives = 45/104 (43%) Frame = +3 Query: 156 KEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTM 335 K GEG E A + V G L NGT F G +P + VI G + + Sbjct: 154 KLGEGEEIKTKNAEITVHYKGSLINGTEFDSSYKRG-KPITLML--KDVILGWQEGLKYI 210 Query: 336 KKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFE 467 KKG IPP +GS + +P NS + +++EL+ + Sbjct: 211 KKGGKIKLIIPPNLGYGSNR----INEIPANSILIFDIELLDIK 250
>FKBA_AERHY (O08437) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA| precursor (EC 5.2.1.8) (PPIase) (Rotamase) Length = 268 Score = 38.5 bits (88), Expect = 0.012 Identities = 37/121 (30%), Positives = 54/121 (44%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 +V K G G +P +V+V G L +GT F G EP F + QVI G V Sbjct: 159 QVEKMGTG-AKPKATDIVKVHYTGTLTDGTKFDSSVDRG-EPATFPLN--QVIPGWTEGV 214 Query: 327 VTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAE 506 M G +P + A+G +P N+ + ++VEL++ EK D NA+ Sbjct: 215 QLMPVGSKFKFFLPSKLAYGEHGA----GSIPANAVLVFDVELLAIEKPAADGD---NAK 267 Query: 507 K 509 K Sbjct: 268 K 268
>FKB10_MOUSE (Q61576) FK506-binding protein 10 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65) Length = 581 Score = 38.5 bits (88), Expect = 0.012 Identities = 28/82 (34%), Positives = 40/82 (48%) Frame = +3 Query: 222 LDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETK 401 LD +F+ H+ + P E +VIEGLD + M GE +PP A G + Sbjct: 410 LDGTRLFSS--HDYEAPQEITLGANKVIEGLDRGLQGMCVGERRQLIVPPHLAHGENGAR 467 Query: 402 LDLAVVPPNSTVFYEVELVSFE 467 VP ++ + +EVELVS E Sbjct: 468 ----GVPGSAVLLFEVELVSRE 485 Score = 38.1 bits (87), Expect = 0.016 Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 1/152 (0%) Frame = +3 Query: 45 VEGAVPPNSTLHIDLELVS-WKTVTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGK 221 V G +PP++TL+ D+ L+ W + IL L+ + VR G Sbjct: 129 VAGLIPPDATLYFDVVLLDVWNKADTV--QSTIL---LRPPYCPRMVQNSDFVRYHYNGT 183 Query: 222 LDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETK 401 L +GT F G ++ +I+G+D ++ M GE IPP A+G K Sbjct: 184 LLDGTGFDNSYSRGGT-YDTYIGSGWLIKGMDQGLLGMCPGEKRKIIIPPFLAYGE---K 239 Query: 402 LDLAVVPPNSTVFYEVELVSFEKEKESWDLKS 497 V+PP +++ + V L+ K++ L++ Sbjct: 240 GYGTVIPPQASLVFYVLLLDVHNPKDTVQLET 271
>MIP_CHLMU (Q9PJK1) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 243 Score = 38.1 bits (87), Expect = 0.016 Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 3/122 (2%) Frame = +3 Query: 126 DDKRILKKVLKEGEGYE---RPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEE 296 + ++ +++KEG G +PN + G NG VF D T Sbjct: 132 EPNKLQYRIVKEGTGRVLTGKPN----ALLHYTGSFINGKVFDTSEKNKDPILLPLT--- 184 Query: 297 QVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEK 476 +VI G + M++GEV + I P+ A+G++ +PPNS + +EV+L+ + Sbjct: 185 KVISGFSQGMQGMREGEVRVLYIHPDLAYGTS------GQLPPNSLLIFEVKLIEANDDN 238 Query: 477 ES 482 S Sbjct: 239 VS 240
>MIP_CHLTR (P26623) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) (27 kDa membrane protein) (Chl-Mip) Length = 243 Score = 37.7 bits (86), Expect = 0.021 Identities = 31/119 (26%), Positives = 53/119 (44%) Frame = +3 Query: 126 DDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVI 305 + ++ +V+KEG G + + G +G VF + EP + VI Sbjct: 132 EPNKLQYRVVKEGTGRVLSGKPTAL-LHYTGSFIDGKVFDSS-EKNKEPILLPLTK--VI 187 Query: 306 EGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKES 482 G + MK+GEV + I P+ A+G+ +PPNS + +EV+L+ + S Sbjct: 188 PGFSQGMQGMKEGEVRVLYIHPDLAYGTA------GQLPPNSLLIFEVKLIEANDDNVS 240
>MIP_CHLPN (Q9Z7P3) Peptidyl-prolyl cis-trans isomerase Mip precursor (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 258 Score = 37.0 bits (84), Expect = 0.035 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGD-EPFEFKTDEEQVIEGLDTT 323 K++KEG G + + + G NG VF+ EG+ EP Q I G Sbjct: 147 KIIKEGAGKAISGKPSAL-LHYKGSFINGQVFSSS--EGNNEPILLPLG--QTIPGFALG 201 Query: 324 VVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 + MK+GE + I P+ A+G+ +PPNS + +E+ L+ Sbjct: 202 MQGMKEGETRVLYIHPDLAYGTA------GQLPPNSLLIFEINLI 240
>FKBA_BUCAI (P57599) FKBP-type peptidyl-prolyl cis-trans isomerase fkpA (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 241 Score = 36.2 bits (82), Expect = 0.060 Identities = 31/101 (30%), Positives = 45/101 (44%) Frame = +3 Query: 156 KEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTM 335 + GEG E D + V G L NG F G P + + VI G + + Sbjct: 143 RAGEG-EALKDETKITVHYKGTLINGLEFDNSYKRG-RPVSLRLKD--VILGWKEGLKYI 198 Query: 336 KKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV 458 KKG IPP A+G+ E +P NST+ +++EL+ Sbjct: 199 KKGGKIKLVIPPNLAYGTEEVN----GIPANSTLIFDIELL 235
>FKB14_PONPY (Q5R941) FK506-binding protein 14 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 211 Score = 35.4 bits (80), Expect = 0.10 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 12/135 (8%) Frame = +3 Query: 171 YERPNDGAVVRVRLIGKLD-NGTVF-TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKG 344 + + G ++ V G L+ +G++F + H +P F + ++G D + M G Sbjct: 39 HRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVG 98 Query: 345 EVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV----------SFEKEKESWDLK 494 E IPP +G K +PP ST+ + ++L+ SF++ + D K Sbjct: 99 EKRKLIIPPALGYG----KEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWK 154 Query: 495 SNAEKIEAASKKKDE 539 + ++++A KK+ E Sbjct: 155 LSKDEVKAYLKKEFE 169
>FKB14_HUMAN (Q9NWM8) FK506-binding protein 14 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (22 kDa FK506-binding protein) (FKBP-22) Length = 211 Score = 35.4 bits (80), Expect = 0.10 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 12/135 (8%) Frame = +3 Query: 171 YERPNDGAVVRVRLIGKLD-NGTVF-TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKG 344 + + G ++ V G L+ +G++F + H +P F + ++G D + M G Sbjct: 39 HRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVG 98 Query: 345 EVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELV----------SFEKEKESWDLK 494 E IPP +G K +PP ST+ + ++L+ SF++ + D K Sbjct: 99 EKRKLIIPPALGYG----KEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWK 154 Query: 495 SNAEKIEAASKKKDE 539 + ++++A KK+ E Sbjct: 155 LSKDEVKAYLKKEFE 169
>FKBP1_METJA (Q57726) Putative FKBP-type peptidyl-prolyl cis-trans isomerase| MJ0278 (EC 5.2.1.8) (PPIase) (Rotamase) Length = 157 Score = 35.0 bits (79), Expect = 0.13 Identities = 16/46 (34%), Positives = 24/46 (52%) Frame = +3 Query: 267 EPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKL 404 EP F ++IEG + V+ M+ GE IPPE +G + +L Sbjct: 45 EPIGFIVGNGELIEGFEEAVIGMEVGEEKTVTIPPEKGYGLRDERL 90
>FKB11_HUMAN (Q9NYL4) FK506-binding protein 11 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (19 kDa FK506-binding protein) (FKBP-19) Length = 201 Score = 34.7 bits (78), Expect = 0.18 Identities = 25/91 (27%), Positives = 43/91 (47%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G + + G L +G + +P + ++QVI GL+ +++ M GE A IP Sbjct: 57 GDTLHIHYTGSLVDGRIIDTSLTR--DPLVIELGQKQVIPGLEQSLLDMCVGEKRRAIIP 114 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVS 461 A+G VP ++ V Y+VEL++ Sbjct: 115 SHLAYGKRGFP---PSVPADAVVQYDVELIA 142
>FKB11_MOUSE (Q9D1M7) FK506-binding protein 11 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (19 kDa FK506-binding protein) (FKBP-19) Length = 201 Score = 34.3 bits (77), Expect = 0.23 Identities = 24/91 (26%), Positives = 43/91 (47%) Frame = +3 Query: 189 GAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIP 368 G + + G L +G + +P + ++QVI GL+ +++ M GE A IP Sbjct: 57 GDTLHIHYTGSLVDGRIIDTSLTR--DPLVIELGQKQVIPGLEQSLLDMCVGEKRRAVIP 114 Query: 369 PEHAFGSTETKLDLAVVPPNSTVFYEVELVS 461 A+G +P ++ V Y+VEL++ Sbjct: 115 SHLAYGKRGYP---PSIPADAVVQYDVELIA 142
>CH10_FRATU (P94797) 10 kDa chaperonin (Protein Cpn10) (groES protein)| Length = 95 Score = 34.3 bits (77), Expect = 0.23 Identities = 22/75 (29%), Positives = 37/75 (49%) Frame = +3 Query: 126 DDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVI 305 ++K+ ++ G E+P+ G VV V KLDNGT GD+ K +V Sbjct: 17 EEKKSAGGIILTGNAQEKPSQGEVVAVGNGKKLDNGTTLPMDVKVGDKVLFGKYSGSEVK 76 Query: 306 EGLDTTVVTMKKGEV 350 G D T++ M++ ++ Sbjct: 77 VG-DETLLMMREEDI 90
>SLYD_TREPA (O83369) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 176 Score = 33.5 bits (75), Expect = 0.39 Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 4/82 (4%) Frame = +3 Query: 195 VVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPE 374 VV + + D G + G E+ +I GL+T ++ ++GE IPP Sbjct: 8 VVNIEYTLRDDTGEIIDSSDVMG--ALEYVQGHGMIIPGLETALINREEGEEFSVTIPPV 65 Query: 375 HAFGSTETKLDLAV----VPPN 428 A+G + L + V PPN Sbjct: 66 GAYGEVQEDLRMTVGRDQFPPN 87
>CWC26_YARLI (Q6CAX1) Pre-mRNA-splicing factor CWC26| Length = 221 Score = 33.1 bits (74), Expect = 0.51 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Frame = +3 Query: 282 KTDEEQVIEGL--DTTVVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVEL 455 KT + +++EGL DT +T ++ + A PP A G +T A+ P TV+ + Sbjct: 15 KTKKRKLVEGLDVDTAPITQRQTQQA---PPPPRAKGGWKTLSGKAIDPVEETVYRDASG 71 Query: 456 VSFEKEKESWDLKSNAEKIEAASKKKDE 539 + + L+ ++ EAA ++K E Sbjct: 72 NIISVDDQISVLQQRQQEKEAAERRKKE 99
>FKBX_SHIFL (P0AEM3) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 33.1 bits (74), Expect = 0.51 Identities = 20/71 (28%), Positives = 34/71 (47%) Frame = +3 Query: 174 ERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVA 353 E + V V KLD+GT + G +P F+ + + EGL+ ++ +K G+ Sbjct: 2 ESVQSNSAVLVHFTLKLDDGTTAESTRNNG-KPALFRLGDASLSEGLEQHLLGLKVGDKT 60 Query: 354 LARIPPEHAFG 386 + P+ AFG Sbjct: 61 TFSLEPDAAFG 71
>FKBX_ECOLI (P0AEM0) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 33.1 bits (74), Expect = 0.51 Identities = 20/71 (28%), Positives = 34/71 (47%) Frame = +3 Query: 174 ERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVA 353 E + V V KLD+GT + G +P F+ + + EGL+ ++ +K G+ Sbjct: 2 ESVQSNSAVLVHFTLKLDDGTTAESTRNNG-KPALFRLGDASLSEGLEQHLLGLKVGDKT 60 Query: 354 LARIPPEHAFG 386 + P+ AFG Sbjct: 61 TFSLEPDAAFG 71
>FKBX_ECOL6 (P0AEM1) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 33.1 bits (74), Expect = 0.51 Identities = 20/71 (28%), Positives = 34/71 (47%) Frame = +3 Query: 174 ERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVA 353 E + V V KLD+GT + G +P F+ + + EGL+ ++ +K G+ Sbjct: 2 ESVQSNSAVLVHFTLKLDDGTTAESTRNNG-KPALFRLGDASLSEGLEQHLLGLKVGDKT 60 Query: 354 LARIPPEHAFG 386 + P+ AFG Sbjct: 61 TFSLEPDAAFG 71
>FKBX_ECO57 (P0AEM2) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 148 Score = 33.1 bits (74), Expect = 0.51 Identities = 20/71 (28%), Positives = 34/71 (47%) Frame = +3 Query: 174 ERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVA 353 E + V V KLD+GT + G +P F+ + + EGL+ ++ +K G+ Sbjct: 2 ESVQSNSAVLVHFTLKLDDGTTAESTRNNG-KPALFRLGDASLSEGLEQHLLGLKVGDKT 60 Query: 354 LARIPPEHAFG 386 + P+ AFG Sbjct: 61 TFSLEPDAAFG 71
>SLYD_HELPY (O25748) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 185 Score = 32.7 bits (73), Expect = 0.67 Identities = 23/76 (30%), Positives = 34/76 (44%) Frame = +3 Query: 225 DNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKL 404 + G+ + EP EF Q+I GL+ V+ + GE I PE A+G E+ Sbjct: 21 EQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY 80 Query: 405 DLAVVPPNSTVFYEVE 452 L VP + E+E Sbjct: 81 -LQEVPRDQFEGIELE 95
>FKBP2_METJA (Q58235) Putative FKBP-type peptidyl-prolyl cis-trans isomerase| MJ0825 (EC 5.2.1.8) (PPIase) (Rotamase) Length = 231 Score = 32.7 bits (73), Expect = 0.67 Identities = 16/42 (38%), Positives = 21/42 (50%) Frame = +3 Query: 270 PFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTE 395 P E QV+ GLD ++ M GE +PPE AFG + Sbjct: 43 PVAIFAGEGQVLPGLDEAILEMDVGEEREVVLPPEKAFGKRD 84
>KAPR_YARLI (Q6C2X0) cAMP-dependent protein kinase regulatory subunit (PKA| regulatory subunit) Length = 375 Score = 32.0 bits (71), Expect = 1.1 Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 13/124 (10%) Frame = +3 Query: 87 LELVSWKTVTLIGDDKR------ILKKV--LKEGEGYERPNDGAVVRVRLIGKLDNGTVF 242 L+ V+++ + L G +R LK+V L + YER + +++ + GT Sbjct: 232 LDRVTFRKILLDGTHQRRSMYDGFLKEVPILSDLGSYERNKLADALTSQVV---EPGTAV 288 Query: 243 TKKGHEGDEPFEFKTDEEQVIE-GLDTTVVTMKKG----EVALARIPPEHAFGSTETKLD 407 +G GD + ++ E +V + G V T+K+G EVAL P A + +TKL Sbjct: 289 ITEGEAGDAFYLVESGEAEVTKKGESGVVATLKQGDYFGEVALLNDLPRQATVTAKTKLK 348 Query: 408 LAVV 419 +A + Sbjct: 349 VATL 352
>AIP_HUMAN (O00170) AH receptor-interacting protein (AIP) (Aryl-hydrocarbon| receptor-interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2) Length = 330 Score = 31.6 bits (70), Expect = 1.5 Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Frame = +3 Query: 138 ILKKVLKEGEGYERPN--DG--AVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVI 305 I K+V++EG G E P+ DG A R + D GTV G +P E ++ + Sbjct: 13 IQKRVIQEGRG-ELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARG-KPMELIIGKKFKL 70 Query: 306 EGLDTTVVTMKKGEVA 353 +T V TM++GE+A Sbjct: 71 PVWETIVCTMREGEIA 86
>SLYD_HELPJ (Q9ZK89) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC| 5.2.1.8) (PPIase) (Rotamase) Length = 185 Score = 31.2 bits (69), Expect = 1.9 Identities = 17/44 (38%), Positives = 23/44 (52%) Frame = +3 Query: 267 EPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTET 398 EP EF Q+I GL+ V+ + GE I PE A+G E+ Sbjct: 35 EPLEFIIGANQIIVGLEKAVLKAQIGEWEEIVIAPEEAYGVYES 78
>FKBP7_HUMAN (Q9Y680) FK506-binding protein 7 precursor (EC 5.2.1.8)| (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (FKBP-23) Length = 259 Score = 30.4 bits (67), Expect = 3.3 Identities = 22/80 (27%), Positives = 31/80 (38%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTV 326 K K+G+ DG + + D + + P F QVI+GLD + Sbjct: 48 KTSKKGDLLNAHYDGYLAK-------DGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAM 100 Query: 327 VTMKKGEVALARIPPEHAFG 386 M GE IPP A+G Sbjct: 101 TDMCPGEKRKVVIPPSFAYG 120
>SYR_METAC (Q8TUM3) Arginyl-tRNA synthetase (EC 6.1.1.19) (Arginine--tRNA| ligase) (ArgRS) Length = 567 Score = 30.0 bits (66), Expect = 4.3 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 10/162 (6%) Frame = +3 Query: 84 DLELVSWKT------VTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFT 245 DL WK + + G D +++ L+ + VV + L G++ T Sbjct: 311 DLAYHEWKAGQADRIIDVFGADHKLISGQLRATLNAIGIKEPEVVIFEFVS-LPEGSMST 369 Query: 246 KKGH--EGDEPFEFKTDE--EQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 ++G D+ F+ T+ EQV T KK + I G+ + + Sbjct: 370 RRGQFISADDLFDRVTEAAFEQVESRRPETSTEFKKQVAEMVGI------GAVRYDI-VR 422 Query: 414 VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 V P STVF E + FEK+ + S+A K KDE Sbjct: 423 VSPEKSTVFNWKEALDFEKQGAPYIQYSHARACSILEKAKDE 464
>RL7A_ORYSA (P35685) 60S ribosomal protein L7a| Length = 258 Score = 29.6 bits (65), Expect = 5.6 Identities = 16/38 (42%), Positives = 20/38 (52%) Frame = +3 Query: 45 VEGAVPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLK 158 + GA+PP LH V W V I +RILK+ LK Sbjct: 34 IGGALPPKKDLH---RFVKWPKVVRIQRQRRILKQRLK 68
>UBP25_MOUSE (P57080) Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15)| (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25) Length = 1055 Score = 29.6 bits (65), Expect = 5.6 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 4/47 (8%) Frame = +3 Query: 408 LAVVPPNSTVFYEVELVSFEKEKESWDL----KSNAEKIEAASKKKD 536 + +PP+ F E + FEKE E WD +S EK+ AA K ++ Sbjct: 679 METLPPDLRDFVEEDNQRFEKELEEWDTQLAQRSLQEKLLAAPKLRE 725
>CH10_OLEAN (Q8KM31) 10 kDa chaperonin (Protein Cpn10) (groES protein)| Length = 97 Score = 29.6 bits (65), Expect = 5.6 Identities = 15/39 (38%), Positives = 21/39 (53%) Frame = +3 Query: 150 VLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGD 266 ++ G E+PN G V+ V LDNG+V +EGD Sbjct: 25 IILPGAAAEKPNQGVVISVGTGRILDNGSVQALAVNEGD 63
>KR16_ICHV1 (Q00098) Gene 16 protein kinase (EC 2.7.11.1)| Length = 387 Score = 29.6 bits (65), Expect = 5.6 Identities = 14/33 (42%), Positives = 21/33 (63%) Frame = +3 Query: 81 IDLELVSWKTVTLIGDDKRILKKVLKEGEGYER 179 I +E+ +W+ IG R+L+ VL EGEG E+ Sbjct: 138 IPMEVYAWEMAYKIGAAPRLLRWVLIEGEGIEQ 170
>IF2_PROVU (Q9ZF22) Translation initiation factor IF-2| Length = 917 Score = 29.6 bits (65), Expect = 5.6 Identities = 40/171 (23%), Positives = 67/171 (39%), Gaps = 7/171 (4%) Frame = +3 Query: 3 HNMVLASKXRPASEVEGAVPPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERP 182 + + A + EV+ A P + +E++ V GD+ +++ K E Sbjct: 630 YGRIRAMRNELGQEVQSAGPS-----MPVEILGLSNVPSAGDEATVVRDEKKARE-VALY 683 Query: 183 NDGAVVRVRLI----GKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEV 350 G V+L KL+N ++G + KTD + E + +V + EV Sbjct: 684 RQGKFREVKLARQQKSKLENMFANMEEGKVSELNIVLKTDVQGTCEAITDALVKLSTDEV 743 Query: 351 ALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVSFEK---EKESWDLK 494 L RI G TET LA + + V + + E+ES DL+ Sbjct: 744 KL-RIIGSGVGGITETDATLAAASEAIILGFNVRADASARRIIEQESVDLR 793
>PALF_YARLI (Q9UVF5) pH-response regulator protein palF/RIM8| Length = 881 Score = 29.3 bits (64), Expect = 7.4 Identities = 16/45 (35%), Positives = 20/45 (44%) Frame = +3 Query: 240 FTKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPE 374 F+K DEP F+ D Q + L T VT RIPP+ Sbjct: 408 FSKVTCNDDEPQSFRKDLSQTVSPLYTDPVTFSSTVSTTLRIPPD 452
>AIP_CERAE (O97628) AH receptor-interacting protein (AIP) (Aryl-hydrocarbon| receptor-interacting protein) (HBV-X-associated protein 2) (p38) Length = 330 Score = 29.3 bits (64), Expect = 7.4 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Frame = +3 Query: 138 ILKKVLKEGEGYERPN--DG--AVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVI 305 I K+V++EG G E P+ DG A R + + GTV G +P E ++ + Sbjct: 13 IQKRVIQEGRG-ELPDFQDGTKATFHYRTLHSDNEGTVLDDSRVRG-KPMELIIGKKFKL 70 Query: 306 EGLDTTVVTMKKGEVA 353 +T V TM++GE+A Sbjct: 71 PVWETIVCTMREGEIA 86
>PSD_BORPE (Q7VYM4) Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65)| [Contains: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain] Length = 297 Score = 28.9 bits (63), Expect = 9.6 Identities = 13/26 (50%), Positives = 17/26 (65%) Frame = +3 Query: 180 PNDGAVVRVRLIGKLDNGTVFTKKGH 257 P DGA+ + IG +DNG +F KGH Sbjct: 90 PADGAISQ---IGAIDNGRIFQAKGH 112
>PSD_BORPA (Q7W6I5) Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65)| [Contains: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain] Length = 297 Score = 28.9 bits (63), Expect = 9.6 Identities = 13/26 (50%), Positives = 17/26 (65%) Frame = +3 Query: 180 PNDGAVVRVRLIGKLDNGTVFTKKGH 257 P DGA+ + IG +DNG +F KGH Sbjct: 90 PADGAISQ---IGAIDNGRIFQAKGH 112
>PSD_BORBR (Q7WIF7) Phosphatidylserine decarboxylase proenzyme (EC 4.1.1.65)| [Contains: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain] Length = 297 Score = 28.9 bits (63), Expect = 9.6 Identities = 13/26 (50%), Positives = 17/26 (65%) Frame = +3 Query: 180 PNDGAVVRVRLIGKLDNGTVFTKKGH 257 P DGA+ + IG +DNG +F KGH Sbjct: 90 PADGAISQ---IGAIDNGRIFQAKGH 112
>MQO1_PSEAE (Q9HYF4) Probable malate:quinone oxidoreductase 1 (EC 1.1.99.16)| (Malate dehydrogenase [acceptor] 1) (MQO 1) Length = 523 Score = 28.9 bits (63), Expect = 9.6 Identities = 14/41 (34%), Positives = 19/41 (46%) Frame = +3 Query: 60 PPNSTLHIDLELVSWKTVTLIGDDKRILKKVLKEGEGYERP 182 PP S H+D ++ K V L G K LK G ++ P Sbjct: 317 PPMSVPHLDTRMIDGKPVLLFGPFATFSTKFLKNGSLWDLP 357
>Y1583_GEOMG (Q39VA9) UPF0090 protein Gmet_1583| Length = 159 Score = 28.9 bits (63), Expect = 9.6 Identities = 25/76 (32%), Positives = 35/76 (46%) Frame = +3 Query: 141 LKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDT 320 L + LK YER G +V+VR +++ +K GD +EGL Sbjct: 84 LNRPLKRESDYERYR-GRLVKVRTYDVVEDEAGNRRKTFLGD------------LEGLAG 130 Query: 321 TVVTMKKGEVALARIP 368 VVT+K E +ARIP Sbjct: 131 GVVTLKLREGQMARIP 146
>PATL2_ARATH (Q56ZI2) Patellin-2| Length = 683 Score = 28.9 bits (63), Expect = 9.6 Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 20/119 (16%) Frame = +3 Query: 243 TKKGHEGDEPFEFKTDEEQVIEGLDTTVVTMKKGEVALARIPPEH--------------- 377 TK+ + P +T +E+++ V KK E +A P E Sbjct: 155 TKEEEKSAAPATVETKKEEILAAPAPIVAETKKEETPVAPAPVETKPAAPVVAETKKEEI 214 Query: 378 ---AFGSTETKLDLAVVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAA--SKKKDE 539 A +TETK++ VVP +T V + E+EK + E+ +AA KK+E Sbjct: 215 LPAAPVTTETKVEEKVVPVETTPAAPVTTETKEEEKAAPVTTETKEEEKAAPGETKKEE 273
>UBP25_HUMAN (Q9UHP3) Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15)| (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21) Length = 1087 Score = 28.9 bits (63), Expect = 9.6 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 4/47 (8%) Frame = +3 Query: 408 LAVVPPNSTVFYEVELVSFEKEKESWDL----KSNAEKIEAASKKKD 536 + +PP+ F E + FEKE E WD K+ EK+ A+ K ++ Sbjct: 678 IETLPPDLRDFVEEDNQRFEKELEEWDAQLAQKALQEKLLASQKLRE 724
>SYR_METMA (Q8PX74) Arginyl-tRNA synthetase (EC 6.1.1.19) (Arginine--tRNA| ligase) (ArgRS) Length = 569 Score = 28.9 bits (63), Expect = 9.6 Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 11/163 (6%) Frame = +3 Query: 84 DLELVSWKT------VTLIGDDKRILKKVLKEGEGYERPNDGAVVRVRLIGKLDNGTVFT 245 DL WK + + G D +++ L+ + VV + L G++ T Sbjct: 313 DLAYHEWKAGQADRIIDVFGADHKLISGQLRATLNAIGVKEPEVVIFEFVS-LPEGSMST 371 Query: 246 KKGH--EGDEPFEFKTDE--EQVIEGLDTTVVTMKKGEVALARIPPEHAFGSTETKLDLA 413 ++G D+ F+ T EQV T KK +VA A G + D+ Sbjct: 372 RRGQFISADDLFDRVTGAAFEQVETRRPETSYEFKK-QVA-------EAVGLGAVRYDIV 423 Query: 414 -VVPPNSTVFYEVELVSFEKEKESWDLKSNAEKIEAASKKKDE 539 V P STVF E + FEK+ + S+A K K+E Sbjct: 424 RVSPEKSTVFNWKEALDFEKQGAPYIQYSHARACSILEKAKEE 466
>SEM6B_RAT (O70141) Semaphorin-6B precursor (Semaphorin Z) (Sema Z)| Length = 887 Score = 28.9 bits (63), Expect = 9.6 Identities = 13/30 (43%), Positives = 17/30 (56%) Frame = -2 Query: 333 W*PPSYRALR*PVPHPS*TQMVRRLHVLSS 244 W PP+ +LR P PH T +RR H +S Sbjct: 823 WSPPATSSLRRPGPHGPPTAALRRTHTFNS 852
>SEM6B_MOUSE (O54951) Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB)| (Semaphorin N) (Sema N) Length = 886 Score = 28.9 bits (63), Expect = 9.6 Identities = 13/30 (43%), Positives = 17/30 (56%) Frame = -2 Query: 333 W*PPSYRALR*PVPHPS*TQMVRRLHVLSS 244 W PP+ +LR P PH T +RR H +S Sbjct: 822 WSPPATSSLRRPGPHGPPTAALRRTHTFNS 851
>FKBP_STRCH (P28725) FK506-binding protein (Peptidyl-prolyl cis-trans| isomerase) (PPIase) (EC 5.2.1.8) (Rotamase) Length = 124 Score = 28.9 bits (63), Expect = 9.6 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 1/106 (0%) Frame = +3 Query: 147 KVLKEGEGYERPNDGAVVRVRLIG-KLDNGTVFTKKGHEGDEPFEFKTDEEQVIEGLDTT 323 K + EG+G G V V +G G F + G P +F+ QVI G D Sbjct: 22 KDIWEGDG-PVAQAGQTVSVHYVGVAFSTGEEFDASWNRGT-PLQFQLGAGQVISGWDQG 79 Query: 324 VVTMKKGEVALARIPPEHAFGSTETKLDLAVVPPNSTVFYEVELVS 461 V MK G IP A+G + + P T+ + +LV+ Sbjct: 80 VQGMKVGGRRELIIPAHLAYG--DRGAGGGKIAPGETLIFVCDLVA 123 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 71,312,211 Number of Sequences: 219361 Number of extensions: 1394632 Number of successful extensions: 5013 Number of sequences better than 10.0: 156 Number of HSP's better than 10.0 without gapping: 4630 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4847 length of database: 80,573,946 effective HSP length: 105 effective length of database: 57,541,041 effective search space used: 4258037034 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
