Clone Name	bags11p24
Clone Library Name	barley_pub

---

No.	Definition	Score (bits)	E Value
1	FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precurso...	384	e-106
2	FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precu...	382	e-106
3	FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precu...	369	e-102
4	FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precurso...	353	3e-97
5	FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precurso...	348	9e-96
6	FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-depen...	238	1e-62
7	FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (...	236	4e-62
8	FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-depen...	201	1e-51
9	FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-depen...	194	2e-49
10	FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-de...	189	7e-48
11	FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-de...	189	7e-48
12	SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	119	5e-27
13	SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	119	9e-27
14	YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C...	117	3e-26
15	GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	115	8e-26
16	SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	113	5e-25
17	GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	112	9e-25
18	GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	112	9e-25
19	GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	111	1e-24
20	GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	108	1e-23
21	SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	105	1e-22
22	SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	105	1e-22
23	SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	105	1e-22
24	SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	105	1e-22
25	SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.9...	103	3e-22
26	YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10...	103	4e-22
27	SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	103	5e-22
28	SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	102	7e-22
29	SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	102	7e-22
30	SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	102	9e-22
31	YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.1...	102	9e-22
32	SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	99	1e-20
33	GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolat...	98	2e-20
34	SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	96	1e-19
35	DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)	94	2e-19
36	CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (...	90	5e-18
37	CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (Ct...	90	5e-18
38	SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	90	5e-18
39	CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (...	90	6e-18
40	DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-...	89	1e-17
41	TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2K...	89	1e-17
42	CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)	88	2e-17
43	CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepre...	88	2e-17
44	TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2K...	88	2e-17
45	VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC...	88	2e-17
46	SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloropl...	88	2e-17
47	DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-...	88	2e-17
48	SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1...	88	2e-17
49	VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC...	87	3e-17
50	CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (d...	87	3e-17
51	DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)	86	9e-17
52	SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1....	86	1e-16
53	LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	85	1e-16
54	LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)	85	2e-16
55	LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	84	2e-16
56	CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)	84	4e-16
57	CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)	83	6e-16
58	GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reduct...	83	7e-16
59	TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2K...	83	7e-16
60	SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase ...	81	3e-15
61	GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reduct...	80	4e-15
62	PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1....	78	2e-14
63	TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1...	78	2e-14
64	LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	78	2e-14
65	LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	77	3e-14
66	LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	75	1e-13
67	Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556...	75	2e-13
68	SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	74	3e-13
69	SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	74	3e-13
70	SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	74	3e-13
71	SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1...	74	3e-13
72	PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1....	74	4e-13
73	DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1...	72	1e-12
74	LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	72	2e-12
75	PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1....	72	2e-12
76	PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1....	68	2e-11
77	PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1....	68	2e-11
78	PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD...	67	4e-11
79	PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1....	65	1e-10
80	PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1....	65	2e-10
81	PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1....	64	3e-10
82	PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1....	64	3e-10
83	PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1....	64	3e-10
84	PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1....	64	5e-10
85	DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-...	63	8e-10
86	LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	62	1e-09
87	PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1....	62	1e-09
88	PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1....	61	3e-09
89	LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	60	4e-09
90	LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	59	1e-08
91	PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1....	59	1e-08
92	PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1....	58	2e-08
93	PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1....	57	4e-08
94	PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1....	57	4e-08
95	PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1....	56	9e-08
96	Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-...	55	1e-07
97	YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1...	55	2e-07
98	LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	55	2e-07
99	LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	55	2e-07
100	LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	55	2e-07
101	LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	55	2e-07
102	LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	55	2e-07
103	PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1....	54	3e-07
104	PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1....	54	4e-07
105	LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	54	4e-07
106	LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	54	4e-07
107	PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1....	53	6e-07
108	PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1....	53	6e-07
109	PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1....	53	8e-07
110	PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1....	52	1e-06
111	LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	52	1e-06
112	LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	50	5e-06
113	LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH...	50	5e-06
114	YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (E...	47	3e-05
115	PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1....	45	2e-04
116	PDXB_PORGI (Q7MV70) Erythronate-4-phosphate dehydrogenase (EC 1....	43	6e-04
117	HEM1_METJA (Q60172) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	39	0.009
118	YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C...	35	0.13
119	PUR6_CANGA (O74197) Phosphoribosylaminoimidazole carboxylase (EC...	35	0.13
120	HEM1_PROMM (Q7V809) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	35	0.17
121	STRI_STRGR (P09400) Streptomycin biosynthesis protein strI (EC 1...	35	0.23
122	SAHH_METKA (P58855) Adenosylhomocysteinase (EC 3.3.1.1) (S-adeno...	34	0.38
123	TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2....	34	0.38
124	TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC ...	34	0.38
125	LACC_STAAR (Q6GEN6) Tagatose-6-phosphate kinase (EC 2.7.1.144) (...	33	0.50
126	SYH_THEAC (Q9HLX5) Histidyl-tRNA synthetase (EC 6.1.1.21) (Histi...	33	0.66
127	HEM1_ARCFU (O28304) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	33	0.86
128	ARODE_CHLMU (P56961) Shikimate biosynthesis protein aroDE [Inclu...	32	1.5
129	HEM1_PROMP (Q7V1T7) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	32	1.5
130	HEM1_METAC (Q8TT60) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	32	1.9
131	ILVC2_SULSO (Q97YJ9) Putative ketol-acid reductoisomerase 2 (EC ...	32	1.9
132	VPS41_CAEEL (Q19954) Vacuolar assembly protein VPS41 homolog	31	2.5
133	TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC ...	31	2.5
134	MET8_YEAST (P15807) Siroheme biosynthesis protein MET8 [Includes...	31	2.5
135	TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC ...	31	2.5
136	HEM1_OCEIH (Q8EPM7) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	31	2.5
137	RFC1_MOUSE (P35601) Activator 1 140 kDa subunit (Replication fac...	31	2.5
138	DHLE_BACLI (Q53560) Leucine dehydrogenase (EC 1.4.1.9) (LeuDH)	31	3.3
139	HEM1_SYNPX (Q7U769) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	31	3.3
140	HEM1_PROMA (Q7VCA1) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)	31	3.3
141	TALA_SALTY (Q8ZN83) Transaldolase A (EC 2.2.1.2)	30	4.2
142	TALA_SALTI (Q8Z4T0) Transaldolase A (EC 2.2.1.2)	30	4.2
143	TAL2_SALCH (Q57LN7) Transaldolase 2 (EC 2.2.1.2)	30	4.2
144	HYPF2_RALEU (O07451) Carbamoyltransferase hypF2 (EC 2.1.3.-) (Ca...	30	4.2
145	CH60_CHLMU (Q59322) 60 kDa chaperonin (Protein Cpn60) (groEL pro...	30	4.2
146	PURK_STAAW (Q8NX94) Phosphoribosylaminoimidazole carboxylase ATP...	30	4.2
147	PURK_STAAS (Q6GAE8) Phosphoribosylaminoimidazole carboxylase ATP...	30	4.2
148	PURK_STAAN (Q7A695) Phosphoribosylaminoimidazole carboxylase ATP...	30	4.2
149	PURK_STAAM (Q99V32) Phosphoribosylaminoimidazole carboxylase ATP...	30	4.2
150	PURK_STAAC (Q5HH19) Phosphoribosylaminoimidazole carboxylase ATP...	30	4.2
151	PUR6_YEAST (P21264) Phosphoribosylaminoimidazole carboxylase (EC...	30	4.2
152	CH60_CHLTR (P0C0Z7) 60 kDa chaperonin (Protein Cpn60) (groEL pro...	30	5.6
153	SYM_SULSO (Q9UWW2) Methionyl-tRNA synthetase (EC 6.1.1.10) (Meth...	30	5.6
154	SYH_THEVO (Q97CE6) Histidyl-tRNA synthetase (EC 6.1.1.21) (Histi...	30	5.6
155	DHLE_BACST (P13154) Leucine dehydrogenase (EC 1.4.1.9) (LeuDH)	30	5.6
156	PURK_STAAR (Q6GI19) Phosphoribosylaminoimidazole carboxylase ATP...	30	5.6
157	PROC_AQUAE (O66553) Pyrroline-5-carboxylate reductase (EC 1.5.1....	30	5.6
158	DHLE_BACSU (P54531) Leucine dehydrogenase (EC 1.4.1.9) (LeuDH)	30	7.2
159	CH60_CHLTA (Q3KMQ9) 60 kDa chaperonin (Protein Cpn60) (groEL pro...	30	7.2
160	POLG_HCVJL (Q68798) Genome polyprotein [Contains: Core protein p...	30	7.2
161	SAHH_SULTO (Q975T0) Adenosylhomocysteinase (EC 3.3.1.1) (S-adeno...	30	7.2
162	Y612_METJA (Q58029) Probable arogenate/prephenate dehydrogenase ...	29	9.5

---

>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH)
          Length = 377

 Score =  384 bits (986), Expect = e-106
 Identities = 193/203 (95%), Positives = 194/203 (95%)
 Frame = +1

Query: 1   EDMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNT 180
           EDMHVLITTPFHPAYVTAE+IKKAK  ELLLTAGIGSDHIDLP     GLTVA VTGSNT
Sbjct: 87  EDMHVLITTPFHPAYVTAEKIKKAKTPELLLTAGIGSDHIDLPAAAAAGLTVARVTGSNT 146

Query: 181 VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLL 360
           VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGR GRLLL
Sbjct: 147 VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRYGRLLL 206

Query: 361 QRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK 540
           QRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK
Sbjct: 207 QRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK 266

Query: 541 EKIAKMKKGVIIVNNARGAIMDT 609
           EKIAKMKKGVIIVNNARGAIMDT
Sbjct: 267 EKIAKMKKGVIIVNNARGAIMDT 289

---

>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1)
          Length = 376

 Score =  382 bits (980), Expect = e-106
 Identities = 190/203 (93%), Positives = 197/203 (97%)
 Frame = +1

Query: 1   EDMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNT 180
           EDMHVLITTPFHPAYV+AERIKKAKNLELLLTAGIGSDHIDLP     GLTVAEVTGSNT
Sbjct: 86  EDMHVLITTPFHPAYVSAERIKKAKNLELLLTAGIGSDHIDLPAAAAAGLTVAEVTGSNT 145

Query: 181 VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLL 360
           VSVAEDELMRILILLRNFLPGYQQVV GEWNVAGIA+RAYDLEGKTVGTVGAGRIGRLLL
Sbjct: 146 VSVAEDELMRILILLRNFLPGYQQVVHGEWNVAGIAYRAYDLEGKTVGTVGAGRIGRLLL 205

Query: 361 QRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK 540
           QRLKPFNCNLLYHDRL+I+PELEKEIGAK+EEDLDAMLPKCDV+VINTPLTEKTRGMFNK
Sbjct: 206 QRLKPFNCNLLYHDRLKIDPELEKEIGAKYEEDLDAMLPKCDVIVINTPLTEKTRGMFNK 265

Query: 541 EKIAKMKKGVIIVNNARGAIMDT 609
           E+IAKMKKGVIIVNNARGAIMDT
Sbjct: 266 ERIAKMKKGVIIVNNARGAIMDT 288

---

>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2)
          Length = 378

 Score =  369 bits (947), Expect = e-102
 Identities = 179/203 (88%), Positives = 192/203 (94%)
 Frame = +1

Query: 1   EDMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNT 180
           ED HVLITTPFHPAY+TAERIKKAKNLELLLTAG+GSDHIDLP     GLTVAE+TGSNT
Sbjct: 88  EDAHVLITTPFHPAYITAERIKKAKNLELLLTAGVGSDHIDLPAAAAAGLTVAEITGSNT 147

Query: 181 VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLL 360
           VSVAED+LMRIL+LLRNFLPG+ Q+V GEWNVAGIAHR YDLEGKTVGTVGAGRIGRLLL
Sbjct: 148 VSVAEDQLMRILLLLRNFLPGHHQIVNGEWNVAGIAHRTYDLEGKTVGTVGAGRIGRLLL 207

Query: 361 QRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNK 540
           QRLKPFNCNL+YHDR++I+PELEKEIGAK+EEDLDAMLPKCDVVVIN PLTEKTRGMFNK
Sbjct: 208 QRLKPFNCNLMYHDRVKIDPELEKEIGAKYEEDLDAMLPKCDVVVINMPLTEKTRGMFNK 267

Query: 541 EKIAKMKKGVIIVNNARGAIMDT 609
           E+IAKMKKGV IVNNARGAIMDT
Sbjct: 268 ERIAKMKKGVTIVNNARGAIMDT 290

---

>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH)
          Length = 381

 Score =  353 bits (905), Expect = 3e-97
 Identities = 172/202 (85%), Positives = 189/202 (93%)
 Frame = +1

Query: 4   DMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTV 183
           D+HVLI+TPFHPAYVTAERIKKAKNL+LLLTAGIGSDH+DL      GLTVAEVTGSNTV
Sbjct: 92  DLHVLISTPFHPAYVTAERIKKAKNLQLLLTAGIGSDHVDLKAAAAAGLTVAEVTGSNTV 151

Query: 184 SVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQ 363
           SVAEDELMRILIL+RNFLPG+ QV+ GEWNVA IAHRAYDLEGKTVGTVGAGRIGRLLLQ
Sbjct: 152 SVAEDELMRILILVRNFLPGHHQVINGEWNVAAIAHRAYDLEGKTVGTVGAGRIGRLLLQ 211

Query: 364 RLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 543
           RLKPFNCNLLYHDRL+++ ELE +IGAKFEEDLD ML KCD+VVINTPLTEKT+GMF+KE
Sbjct: 212 RLKPFNCNLLYHDRLKMDSELENQIGAKFEEDLDKMLSKCDIVVINTPLTEKTKGMFDKE 271

Query: 544 KIAKMKKGVIIVNNARGAIMDT 609
           +IAK+KKGV+IVNNARGAIMDT
Sbjct: 272 RIAKLKKGVLIVNNARGAIMDT 293

---

>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC|
           1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH)
          Length = 384

 Score =  348 bits (892), Expect = 9e-96
 Identities = 171/201 (85%), Positives = 185/201 (92%)
 Frame = +1

Query: 4   DMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTV 183
           D+HVLI+TPFHPAYVTAERIKKAKNL+LLLTAGIGSDHIDL      GLTVAEVTGSN V
Sbjct: 95  DLHVLISTPFHPAYVTAERIKKAKNLKLLLTAGIGSDHIDLQAAAAAGLTVAEVTGSNVV 154

Query: 184 SVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQ 363
           SVAEDELMRILIL+RNF+PGY QVVKGEWNVAGIA+RAYDLEGKT+GTVGAGRIG+LLLQ
Sbjct: 155 SVAEDELMRILILMRNFVPGYNQVVKGEWNVAGIAYRAYDLEGKTIGTVGAGRIGKLLLQ 214

Query: 364 RLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 543
           RLKPF CNLLYHDRLQ+ PELEKE GAKF EDL+ MLPKCDV+VIN PLTEKTRGMFNKE
Sbjct: 215 RLKPFGCNLLYHDRLQMAPELEKETGAKFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKE 274

Query: 544 KIAKMKKGVIIVNNARGAIMD 606
            I K+KKGV+IVNNARGAIM+
Sbjct: 275 LIGKLKKGVLIVNNARGAIME 295

---

>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate|
           dehydrogenase) (FDH)
          Length = 375

 Score =  238 bits (607), Expect = 1e-62
 Identities = 121/204 (59%), Positives = 153/204 (75%), Gaps = 3/204 (1%)
 Frame = +1

Query: 1   EDMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXX--GLTVAEVTGS 174
           ED  ++ITTPFHP Y+TAER+ +AK L+L +TAGIGSDH+DL        G+TVAEVTGS
Sbjct: 60  EDAEIIITTPFHPGYLTAERLARAKKLKLAVTAGIGSDHVDLNAANKTNGGITVAEVTGS 119

Query: 175 NTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRL 354
           N VSVAE  LM IL+L+RNF+P ++Q+ +G W+VA  A   +DLEGK VGTVG GRIG  
Sbjct: 120 NVVSVAEHVLMTILVLVRNFVPAHEQIQEGRWDVAEAAKNEFDLEGKVVGTVGVGRIGER 179

Query: 355 LLQRLKPFNC-NLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGM 531
           +L+RLKPF+C  LLY+D   ++ E E EIG +   DL+ ML +CDVV IN PL EKT+G+
Sbjct: 180 VLRRLKPFDCKELLYYDYQPLSAEKEAEIGCRRVADLEEMLAQCDVVTINCPLHEKTQGL 239

Query: 532 FNKEKIAKMKKGVIIVNNARGAIM 603
           FNKE I+KMKKG  +VN ARGAI+
Sbjct: 240 FNKELISKMKKGSWLVNTARGAIV 263

---

>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent|
           formate dehydrogenase) (FDH)
          Length = 377

 Score =  236 bits (602), Expect = 4e-62
 Identities = 124/220 (56%), Positives = 155/220 (70%), Gaps = 20/220 (9%)
 Frame = +1

Query: 4   DMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXX--GLTVAEVTGSN 177
           D  V+ITTPFHP Y+TAER+ KAKNL+L +TAGIGSDH+DL        G+TVAEVTGSN
Sbjct: 56  DAEVIITTPFHPGYLTAERLAKAKNLKLAVTAGIGSDHVDLDAANKTNGGITVAEVTGSN 115

Query: 178 TVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLL 357
            VSVAE  +M IL+L+RNF+P + Q+  G+WNVA +A   +DLE K VGTVG GRIG  +
Sbjct: 116 VVSVAEHVVMTILLLVRNFVPAHDQIRNGDWNVAAVAKNEFDLENKVVGTVGVGRIGERV 175

Query: 358 LQRLKPFNC-NLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMF 534
           L+RLKPF+C  LLY+D   + PE+EKEIGA+  + L+ M+ +CDVV IN PL EKTRG+F
Sbjct: 176 LRRLKPFDCKELLYYDYQPLRPEVEKEIGARRVDSLEEMVSQCDVVTINCPLHEKTRGLF 235

Query: 535 NKEKIAKMK-----------------KGVIIVNNARGAIM 603
           NKE I+KMK                 KG  +VN ARGAI+
Sbjct: 236 NKELISKMKPGKSALLYLIIPMLMYHKGSWLVNTARGAIV 275

---

>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate|
           dehydrogenase) (FDH)
          Length = 361

 Score =  201 bits (511), Expect = 1e-51
 Identities = 101/202 (50%), Positives = 142/202 (70%), Gaps = 3/202 (1%)
 Frame = +1

Query: 4   DMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXG--LTVAEVTGSN 177
           D  V+I+TPFHPAY+T ERI KAK L+LL+ AG+GSDHIDL      G  ++V EVTGSN
Sbjct: 59  DADVIISTPFHPAYITKERIDKAKKLKLLVVAGVGSDHIDLDYINQSGRDISVLEVTGSN 118

Query: 178 TVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLL 357
            VSVAE  +M +L+L+RNF+P ++Q++ G WNVA IA  ++D+EGK + T+GAGRIG  +
Sbjct: 119 VVSVAEHVVMTMLVLVRNFVPAHEQIISGGWNVAEIAKDSFDIEGKVIATIGAGRIGYRV 178

Query: 358 LQRLKPFN-CNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMF 534
           L+RL  FN   LLY+D   ++ E E+++GA+   D+  ++ + D+V IN PL   ++G+ 
Sbjct: 179 LERLVAFNPKELLYYDYQSLSKEAEEKVGARRVHDIKELVAQADIVTINCPLHAGSKGLV 238

Query: 535 NKEKIAKMKKGVIIVNNARGAI 600
           N E +   KKG  +VN ARGAI
Sbjct: 239 NAELLKHFKKGAWLVNTARGAI 260

---

>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate|
           dehydrogenase) (FDH)
          Length = 400

 Score =  194 bits (492), Expect = 2e-49
 Identities = 101/201 (50%), Positives = 130/201 (64%)
 Frame = +1

Query: 4   DMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTV 183
           D  V+I+ PF PAY+T ERI KAKNL+L LTAGIGSDH+DL       +TVAEVT  N++
Sbjct: 89  DADVVISQPFWPAYLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRNVTVAEVTYCNSI 148

Query: 184 SVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQ 363
           SVAE  +M IL L+RN+LP ++   KG WN+A     AYDLE   VGTV AGRIG  +L+
Sbjct: 149 SVAEHVVMMILSLVRNYLPSHEWARKGGWNIADCVSHAYDLEAMHVGTVAAGRIGLAVLR 208

Query: 364 RLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKE 543
           RL PF+ +L Y DR ++   +EKE+   +    + M P CDVV +N PL  +T  M N E
Sbjct: 209 RLAPFDVHLHYTDRHRLPESVEKELNLTWHATREDMYPVCDVVTLNCPLHPETEHMINDE 268

Query: 544 KIAKMKKGVIIVNNARGAIMD 606
            +   K+G  IVN ARG + D
Sbjct: 269 TLKLFKRGAYIVNTARGKLCD 289

---

>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent|
           formate dehydrogenase 2)
          Length = 376

 Score =  189 bits (479), Expect = 7e-48
 Identities = 100/213 (46%), Positives = 137/213 (64%), Gaps = 13/213 (6%)
 Frame = +1

Query: 1   EDMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNT 180
           +D  ++ITTPF PAY++  RI +A NL+L +TAG+GSDH+DL       +TV EVTGSN 
Sbjct: 63  KDAEIVITTPFFPAYISRNRIAEAPNLKLCVTAGVGSDHVDLEAANERKITVTEVTGSNV 122

Query: 181 VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLL 360
           VSVAE  +  IL+L+RN+  G+QQ + GEW++AG+A   YDLE K + TVGAGRIG  +L
Sbjct: 123 VSVAEHVMATILVLIRNYNGGHQQAINGEWDIAGVAKNEYDLEDKIISTVGAGRIGYRVL 182

Query: 361 QRLKPFN-CNLLYHDRLQINPELEKEIGAKFE------------EDLDAMLPKCDVVVIN 501
           +RL  FN   LLY+D  ++  E    +    +            E L+ M+ + DVV IN
Sbjct: 183 ERLVAFNPKKLLYYDYQELPAEAINRLNEASKLFNGRGDIVQRVEKLEDMVAQSDVVTIN 242

Query: 502 TPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAI 600
            PL + +RG+FNK+ I+ MK G  +VN ARGAI
Sbjct: 243 CPLHKDSRGLFNKKLISHMKDGAYLVNTARGAI 275

---

>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent|
           formate dehydrogenase 1)
          Length = 376

 Score =  189 bits (479), Expect = 7e-48
 Identities = 100/213 (46%), Positives = 137/213 (64%), Gaps = 13/213 (6%)
 Frame = +1

Query: 1   EDMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNT 180
           +D  ++ITTPF PAY++  RI +A NL+L +TAG+GSDH+DL       +TV EVTGSN 
Sbjct: 63  KDAEIVITTPFFPAYISRNRIAEAPNLKLCVTAGVGSDHVDLEAANERKITVTEVTGSNV 122

Query: 181 VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLL 360
           VSVAE  +  IL+L+RN+  G+QQ + GEW++AG+A   YDLE K + TVGAGRIG  +L
Sbjct: 123 VSVAEHVMATILVLIRNYNGGHQQAINGEWDIAGVAKNEYDLEDKIISTVGAGRIGYRVL 182

Query: 361 QRLKPFN-CNLLYHDRLQINPELEKEIGAKFE------------EDLDAMLPKCDVVVIN 501
           +RL  FN   LLY+D  ++  E    +    +            E L+ M+ + DVV IN
Sbjct: 183 ERLVAFNPKKLLYYDYQELPAEAINRLNEASKLFNGRGDIVQRVEKLEDMVAQSDVVTIN 242

Query: 502 TPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAI 600
            PL + +RG+FNK+ I+ MK G  +VN ARGAI
Sbjct: 243 CPLHKDSRGLFNKKLISHMKDGAYLVNTARGAI 275

---

>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 527

 Score =  119 bits (299), Expect = 5e-27
 Identities = 68/187 (36%), Positives = 103/187 (55%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V AE I+ AKNL+++  AG+G D+ID+      G+ V    G NT+S AE  +  +L   
Sbjct: 53  VDAEVIQAAKNLKIIGRAGVGVDNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAA 112

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R      + V +G+W          +L GKT G +G GR+G  + +R K    N+L +D 
Sbjct: 113 RKIPQADRSVKEGKWERK--KFMGIELRGKTAGVIGLGRVGFEVAKRCKALEMNVLAYDP 170

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             ++ E  ++IG K   D D +L   DV+ ++ P T++T G+  K +  KMK GVI+VN 
Sbjct: 171 F-VSKERAEQIGVKL-VDFDTLLASSDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNA 228

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 229 ARGGIVD 235

---

>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 524

 Score =  119 bits (297), Expect = 9e-27
 Identities = 64/187 (34%), Positives = 111/187 (59%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VT + I+KA+ L+++  AG+G D+ID+      G+ V     ++++SVAE  +  +L   
Sbjct: 53  VTRDVIEKAEKLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAA 112

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           RN       + +GEW+      +  +L GKT+G +G GRIG+ +++R K F  N++ +D 
Sbjct: 113 RNIPQATASLKRGEWDRKRF--KGIELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDP 170

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             I  E+ + +G +  +D++ +  + D + ++ PLT KTR +  +E+IA MKK  IIVN 
Sbjct: 171 Y-IPKEVAESMGVELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNC 229

Query: 586 ARGAIMD 606
           ARG ++D
Sbjct: 230 ARGGLID 236

---

>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)|
          Length = 350

 Score =  117 bits (293), Expect = 3e-26
 Identities = 71/173 (41%), Positives = 101/173 (58%), Gaps = 4/173 (2%)
 Frame = +1

Query: 100 GIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVA 279
           G G D ID+       + VA V    + + A+  +  +L  LRNF  G +++++G W  A
Sbjct: 90  GAGYDQIDVEPFKKRHIQVANVPDLVSNATADTHVFLLLGALRNFGIGNRRLIEGNWPEA 149

Query: 280 GIAHRA---YDLEGKTVGTVGAGRIGRLLLQRLKPFNC-NLLYHDRLQINPELEKEIGAK 447
           G A  +   YD EGKTVG +G GRIGR +L+RLKPF   N +YH+R Q+  E  +E G +
Sbjct: 150 GPACGSPFGYDPEGKTVGILGLGRIGRCILERLKPFGFENFIYHNRHQLPSE--EEHGCE 207

Query: 448 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           +    +  L + D+V +N PL   T  + N E I KMK GV+IVN ARGA++D
Sbjct: 208 YV-GFEEFLKRSDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVID 259

---

>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 335

 Score =  115 bits (289), Expect = 8e-26
 Identities = 64/193 (33%), Positives = 108/193 (55%), Gaps = 5/193 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           +  E  ++A  L ++    +G D+ID+      G+ V    G  T + A+     +L   
Sbjct: 58  IDREVFERAPRLRIVANYAVGYDNIDVEEATKRGIYVTNTPGVLTDATADLAFALLLATA 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHR-----AYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNL 390
           R+ + G +    GEW   G+A        YD+ GKT+G +G GRIG+ + +R + F+  +
Sbjct: 118 RHLVKGDKFTRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGFGRIGQAIAKRARGFDMRI 177

Query: 391 LYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGV 570
           LY+ R +  PE+EKE+ A+F+  LD +L + D VV+  PL ++T  M N+E++  MK+  
Sbjct: 178 LYYSRTR-KPEVEKELNAEFKP-LDELLRESDFVVLAVPLNKETYHMINEERLKMMKRTA 235

Query: 571 IIVNNARGAIMDT 609
           I++N ARG ++DT
Sbjct: 236 ILINVARGKVIDT 248

---

>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 525

 Score =  113 bits (282), Expect = 5e-25
 Identities = 68/187 (36%), Positives = 100/187 (53%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VT +   K  +L+++  AG+G D+ID+      G+ V      NT+S AE     I  L+
Sbjct: 52  VTEDLFNKMTSLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLM 111

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R+       V   EWN    A+   +L GKT+G VG GRIG  + QR   F   +   D 
Sbjct: 112 RHIPQANISVKSREWNRT--AYVGSELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDP 169

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             +  E  K+IG       + +L   D++ ++TPLT++T+G+ NKE IAK KKGV ++N 
Sbjct: 170 F-LTEERAKKIGVN-SRTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINC 227

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 228 ARGGIID 234

---

>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 334

 Score =  112 bits (280), Expect = 9e-25
 Identities = 64/193 (33%), Positives = 106/193 (54%), Gaps = 5/193 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           +  E  + A  L ++    +G D+ID+      G+ V       T + A+     +L   
Sbjct: 57  IDKEVFENAPKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATA 116

Query: 226 RNFLPGYQQVVKGEWNVAGIAHR-----AYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNL 390
           R+ + G + V  GEW   G+A        YD+ GKT+G +G GRIG+ + +R K FN  +
Sbjct: 117 RHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMRI 176

Query: 391 LYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGV 570
           LY+ R +   E+E+E+ A+F+  L+ +L + D VV+  PLT +T  + N+E++  MKK  
Sbjct: 177 LYYSRTR-KEEVERELNAEFKP-LEDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTA 234

Query: 571 IIVNNARGAIMDT 609
           I++N ARG ++DT
Sbjct: 235 ILINIARGKVVDT 247

---

>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 336

 Score =  112 bits (280), Expect = 9e-25
 Identities = 66/193 (34%), Positives = 105/193 (54%), Gaps = 5/193 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           +  E  + A  L ++    +G D+ID+      G+ V       T + A+     +L   
Sbjct: 57  IDQEVFENAPRLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLATA 116

Query: 226 RNFLPGYQQVVKGEWNVAGIAHR-----AYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNL 390
           R+ + G + V  GEW   GIA        Y+L GKT+G VG GRIG+ + +R K FN  +
Sbjct: 117 RHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAKGFNMRI 176

Query: 391 LYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGV 570
           LY+ R +   + EKE+GA++   L+ +L + D V++  PLT++T  M N+E++  MK   
Sbjct: 177 LYYSRTR-KSQAEKELGAEYRP-LEEVLKESDFVILAVPLTKETMYMINEERLKLMKPTA 234

Query: 571 IIVNNARGAIMDT 609
           I+VN ARG ++DT
Sbjct: 235 ILVNIARGKVVDT 247

---

>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 333

 Score =  111 bits (278), Expect = 1e-24
 Identities = 67/193 (34%), Positives = 103/193 (53%), Gaps = 5/193 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           + +E    A  L ++    +G D+ID+      G+ V       T + A+     +L   
Sbjct: 57  IDSEVFDAAPRLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTDATADFAWTLLLATA 116

Query: 226 RNFLPGYQQVVKGEWNVAGIAHR-----AYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNL 390
           R  +        GEW   GIA        YD+ GKT+G VG GRIG+ + +R + F   +
Sbjct: 117 RRLIEADHFTRSGEWKRRGIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVARRARGFGMRI 176

Query: 391 LYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGV 570
           LY+ R +  PE EKE+GA+F   L+ +L + D VV+  PLT++T+ M N+E++  MKK  
Sbjct: 177 LYYSRSR-KPEAEKELGAEFRS-LEDLLRESDFVVLAVPLTKETQYMINEERLRLMKKTA 234

Query: 571 IIVNNARGAIMDT 609
           I+VN ARG ++DT
Sbjct: 235 ILVNIARGKVVDT 247

---

>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 331

 Score =  108 bits (270), Expect = 1e-23
 Identities = 61/193 (31%), Positives = 105/193 (54%), Gaps = 5/193 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V  E ++ A  L+++    +G D+ID+      G+ V    G  T + A+     +L + 
Sbjct: 57  VDKELLENAPKLKIIAQYAVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAVA 116

Query: 226 RNFLPGYQQVVKGEWNVAGIAHR-----AYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNL 390
           R  +     V  GEW  + +         Y L+GKT+G VG GRIG+ L +R K F   +
Sbjct: 117 RRIVEADAFVRSGEWKKSEVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKRAKGFGMKI 176

Query: 391 LYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGV 570
           +Y+ R +  PE E+EIGA++  D + +L + D + ++ PLT++T  M  ++++  MK   
Sbjct: 177 IYYSRTR-KPEAEEEIGAEYV-DFETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNA 234

Query: 571 IIVNNARGAIMDT 609
           I++N +RGA++DT
Sbjct: 235 ILINTSRGAVVDT 247

---

>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score =  105 bits (262), Expect = 1e-22
 Identities = 63/187 (33%), Positives = 98/187 (52%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VTA+ I  A+ L+++  AG G D++DL      G+ V      N++S AE     I+ L 
Sbjct: 58  VTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLA 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        +  G+W          +L GKT+G +G GRIGR +  R++ F    + +D 
Sbjct: 118 RQIPQATASMKDGKWERKKFM--GTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDP 175

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           + I+PE+    G + +  L+ + P CD + ++TPL   T G+ N    A+ KKGV +VN 
Sbjct: 176 I-ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNC 233

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 234 ARGGIVD 240

---

>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
           (A10)
          Length = 532

 Score =  105 bits (261), Expect = 1e-22
 Identities = 63/187 (33%), Positives = 99/187 (52%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VTA+ I  A+ L+++  AG G D++DL      G+ V      N++S AE     I+ L 
Sbjct: 58  VTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLA 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        +  G+W+         +L GKT+G +G GRIGR +  R++ F    + +D 
Sbjct: 118 RQIPQATASMKDGKWDRKKFM--GTELNGKTLGILGLGRIGREVATRMQSFGMKTVGYDP 175

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           + I+PE+    G + +  L+ + P CD + ++TPL   T G+ N    A+ KKGV +VN 
Sbjct: 176 I-ISPEVAASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNC 233

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 234 ARGGIVD 240

---

>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score =  105 bits (261), Expect = 1e-22
 Identities = 63/187 (33%), Positives = 98/187 (52%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VTA+ I  A+ L+++  AG G D++DL      G+ V      N++S AE     I+ L 
Sbjct: 58  VTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMIMCLA 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        +  G+W          +L GKT+G +G GRIGR +  R++ F    + +D 
Sbjct: 118 RQIPQATASMKDGKWERKKFM--GTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDP 175

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           + I+PE+    G + +  L+ + P CD + ++TPL   T G+ N    A+ KKGV +VN 
Sbjct: 176 I-ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNC 233

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 234 ARGGIVD 240

---

>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 525

 Score =  105 bits (261), Expect = 1e-22
 Identities = 62/187 (33%), Positives = 103/187 (55%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VT E I+ A  L+++  AG+G D++D+      G+ V     S +++VAE  +  +L L 
Sbjct: 55  VTREVIEAAPRLKIIARAGVGVDNVDVKAATDRGIMVINAPESTSITVAEHSIGLMLALA 114

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R      + V +G+W          +L GKT+G +G GRIG  ++ R K F  +++ +D 
Sbjct: 115 RKIAIADRSVKEGKWEKN--RFMGIELNGKTLGIIGMGRIGSQVVVRTKAFGMDIMVYDP 172

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             I+ E  +E+G     DL+ +L + D+V I+ PLT +TR + ++++   MK    IVN 
Sbjct: 173 -YISKEAAEEMGVTV-TDLETLLRESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNC 230

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 231 ARGGIID 237

---

>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score =  103 bits (258), Expect = 3e-22
 Identities = 62/187 (33%), Positives = 99/187 (52%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VTA+ I  A+ L+++  AG G D++DL      G+ V      N++S AE     ++ L 
Sbjct: 58  VTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLA 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        +  G+W+         +L GKT+G +G GRIGR +  R++ F    + +D 
Sbjct: 118 RQIPQATASMKDGKWDRKKFM--GTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDP 175

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           + I+PE+    G + +  L+ + P CD + ++TPL   T G+ N    A+ KKGV +VN 
Sbjct: 176 I-ISPEVAASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNC 233

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 234 ARGGIVD 240

---

>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)|
          Length = 334

 Score =  103 bits (257), Expect = 4e-22
 Identities = 61/177 (34%), Positives = 100/177 (56%)
 Frame = +1

Query: 76  NLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQV 255
           +++ +   G G + +D+      G+ V+ V  +   + A+  +  +L  LR F  G  ++
Sbjct: 80  SVKFICHLGAGYETVDVAACTARGIQVSHVPKAVDDATADVGIFLMLGALRGFNQGIFEL 139

Query: 256 VKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKE 435
            K  WN       ++D EGKT+G +G G IG+ + +R + F+  ++YH+R  + PE E E
Sbjct: 140 HKNNWNAN--CKPSHDPEGKTLGILGLGGIGKTMAKRARAFDMKIVYHNRTPL-PEEEAE 196

Query: 436 IGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
            GA+F    D +L K DV+ +N PL   TR +  K +  KMK+G++IVN ARGA+MD
Sbjct: 197 -GAEFVS-FDDLLAKSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMD 251

---

>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score =  103 bits (256), Expect = 5e-22
 Identities = 61/187 (32%), Positives = 97/187 (51%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VT++ I  A+ L+++  AG G D++DL      G+ V      N++S AE     I+ L 
Sbjct: 58  VTSDIINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLA 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        +  G+W          +L GK +G +G GRIGR +  R++ F    + +D 
Sbjct: 118 RQIPQAAASMKDGKWERKKFM--GTELNGKVLGILGLGRIGREVATRMQSFGMKTIGYDP 175

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           + I+PE+    G + +  L+ + P CD + ++TPL   T G+ N    A+ KKGV +VN 
Sbjct: 176 I-ISPEVSASFGVQ-QLPLEQIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNC 233

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 234 ARGGIVD 240

---

>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score =  102 bits (255), Expect = 7e-22
 Identities = 62/187 (33%), Positives = 100/187 (53%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V AE +  A  L+++  AG+G D++D+      G+ V     SN  S AE  L  +L   
Sbjct: 55  VDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAAS 114

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        + +  W  +  +    ++ GKTVG VG GRIG+L+ QR+  F   ++ +D 
Sbjct: 115 RQIPAADASLREHTWKRSSFS--GTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDP 172

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             ++P    ++G +    LD +L + D + ++ P T +T G+ +KE +AK K GVIIVN 
Sbjct: 173 Y-VSPARAAQLGIELLS-LDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNA 230

Query: 586 ARGAIMD 606
           ARG ++D
Sbjct: 231 ARGGLVD 237

---

>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score =  102 bits (255), Expect = 7e-22
 Identities = 62/187 (33%), Positives = 100/187 (53%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V AE +  A  L+++  AG+G D++D+      G+ V     SN  S AE  L  +L   
Sbjct: 55  VDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAAS 114

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        + +  W  +  +    ++ GKTVG VG GRIG+L+ QR+  F   ++ +D 
Sbjct: 115 RQIPAADASLREHTWKRSSFS--GTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDP 172

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             ++P    ++G +    LD +L + D + ++ P T +T G+ +KE +AK K GVIIVN 
Sbjct: 173 Y-VSPARAAQLGIELLS-LDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNA 230

Query: 586 ARGAIMD 606
           ARG ++D
Sbjct: 231 ARGGLVD 237

---

>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)|
          Length = 532

 Score =  102 bits (254), Expect = 9e-22
 Identities = 62/187 (33%), Positives = 97/187 (51%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VTA+ I  A+ L+++  AG G D++DL      G+ V      N++S AE     I+ L 
Sbjct: 58  VTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLA 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        +  G+W          +L GKT+G +G GRIGR +  R++      + +D 
Sbjct: 118 RQIPQATASMKDGKWERKKFM--GTELNGKTLGILGLGRIGREVAIRMQSLGMKTIGYDP 175

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           + I+PE+    G + +  L+ + P CD + ++TPL   T G+ N    A+ KKGV +VN 
Sbjct: 176 I-ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNC 233

Query: 586 ARGAIMD 606
           ARG I+D
Sbjct: 234 ARGGIVD 240

---

>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC|
           1.-.-.-)
          Length = 340

 Score =  102 bits (254), Expect = 9e-22
 Identities = 59/175 (33%), Positives = 88/175 (50%)
 Frame = +1

Query: 82  ELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVK 261
           +L +T   G +++D+      G+ VA      T   A   LM  +  LR      Q +  
Sbjct: 85  KLFVTGAAGYNNVDVDWATRNGVYVANTPNGPTEGTANMNLMLFMCTLRGAREAEQSLRL 144

Query: 262 GEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIG 441
           G+W          D  GK VG +G G IG+   Q++ P  C ++YH+R ++  E EK +G
Sbjct: 145 GKWRQN--LSLTDDPYGKRVGIIGMGAIGKSFAQKILPLGCEIVYHNRNRLEAEEEKRLG 202

Query: 442 AKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           A F    D +L   DV+ IN PLT  T  + + ++  KMK GV I+N ARGAI++
Sbjct: 203 ASF-VSFDELLSSSDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIIN 256

---

>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 528

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 60/187 (32%), Positives = 97/187 (51%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V AE +  A  L+++  AG+G D++D+      G+ V     SN  S AE  L  +L   
Sbjct: 55  VDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAAS 114

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R        +    W  +  +    ++ GKTVG VG GRIG+L+  R+  F  +++ +D 
Sbjct: 115 RQIAEADASLRAHIWKRSSFS--GTEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDP 172

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             + P    ++G +     D +L + D + ++ P T +T G+ +KE +AK K GVIIVN 
Sbjct: 173 Y-VAPARAAQLGIELMS-FDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNA 230

Query: 586 ARGAIMD 606
           ARG ++D
Sbjct: 231 ARGGLVD 237

---

>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)|
          Length = 335

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 61/193 (31%), Positives = 100/193 (51%), Gaps = 5/193 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           +  + + +A  L ++    +G D+ID+      G+ V    G  T + AE     IL   
Sbjct: 58  IDCDLLSQAPRLRIVAQMAVGFDNIDVECATRLGIYVTNTPGVLTEATAEFTWALILAAA 117

Query: 226 RNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNL 390
           R  +     V  GEW         +     +L GKT+G +G GRIG  + +  K F   +
Sbjct: 118 RRVVEADHFVRWGEWWRLRTGWHPMMMLGVELRGKTLGILGMGRIGSRVAEIGKAFGMRI 177

Query: 391 LYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGV 570
           +YH R +   E+EKE+GA++   L+ +L + D++ I+ PLT++TR +  + ++  MKK  
Sbjct: 178 IYHSRSR-KREIEKELGAEYRS-LEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTA 235

Query: 571 IIVNNARGAIMDT 609
           I+VN  RGAI+DT
Sbjct: 236 ILVNTGRGAIVDT 248

---

>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 410

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 61/191 (31%), Positives = 102/191 (53%), Gaps = 3/191 (1%)
 Frame = +1

Query: 43  YVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILIL 222
           ++TAE I+ A  L  +    IG++ +DL      G+ V     SNT SVAE  L  IL+L
Sbjct: 65  HLTAEMIEAAPKLIAVGCFCIGTNQVDLNAAKARGIPVFNAPFSNTRSVAELVLGEILLL 124

Query: 223 LRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD 402
           +RN      +V +G WN +  A  ++++ GK +G +G G IG  L    +    ++ ++D
Sbjct: 125 MRNVPQANAEVHRGVWNKS--ATGSHEVRGKKLGIIGYGHIGSQLSIIAESLGMDVYFYD 182

Query: 403 RLQINPELEKEI---GAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
                  +E ++    AK    L+ +L  CDVV ++ P    T+ + N  +IA++K+G I
Sbjct: 183 -------IENKLPLGNAKQVRSLEELLSSCDVVSLHVPELPSTKNLMNVARIAQLKQGAI 235

Query: 574 IVNNARGAIMD 606
           ++N ARG ++D
Sbjct: 236 LINAARGTVVD 246

---

>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)|
          Length = 331

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 60/187 (32%), Positives = 103/187 (55%), Gaps = 8/187 (4%)
 Frame = +1

Query: 73  KNLELLLTAGI--------GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLR 228
           K LE L   G+        G +++DL      G+ V  V   +  +VAE  +  ++ L R
Sbjct: 59  KVLEKLAALGVKIVALRCAGFNNVDLKAAQELGIQVVRVPAYSPEAVAEHTIGLMMTLNR 118

Query: 229 NFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRL 408
                YQ+  +  +++ G+    +++ G+TVG +G G+IG  +++ LK F  N+L +D  
Sbjct: 119 RIHRAYQRTREANFSLEGLI--GFNMYGRTVGVIGTGKIGIAVMRILKGFGMNILAYDPF 176

Query: 409 QINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNA 588
           + NP +E E+G ++ E LD +  K  V+ ++ P T +   + N E  AKMK GV+IVN +
Sbjct: 177 K-NPVVE-ELGGQYVE-LDELYAKSHVITLHCPATPENYHLLNCEAFAKMKDGVMIVNTS 233

Query: 589 RGAIMDT 609
           RG+++DT
Sbjct: 234 RGSLIDT 240

---

>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
          Length = 440

 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 54/197 (27%), Positives = 99/197 (50%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   +T E ++K K L +++  G G D+ID+      G+ V  V  ++    A+  L  
Sbjct: 76  YHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCH 135

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R     +Q + +G        +  +A  A  + G+T+G +G GR+G+ +  R K 
Sbjct: 136 ILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKA 195

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           F  N+L++D   ++  +E+ +G +    L  +L   D V ++  L E    + N   + +
Sbjct: 196 FGFNVLFYDP-YLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQ 254

Query: 556 MKKGVIIVNNARGAIMD 606
           M++G  +VN ARG ++D
Sbjct: 255 MRQGAFLVNTARGGLVD 271

---

>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
           (C-terminal-binding protein 3) (CtBP3) (50 kDa
           BFA-dependent ADP-ribosylation substrate) (BARS-50)
          Length = 430

 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 54/197 (27%), Positives = 99/197 (50%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   +T E ++K K L +++  G G D+ID+      G+ V  V  ++    A+  L  
Sbjct: 65  YHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCH 124

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R     +Q + +G        +  +A  A  + G+T+G +G GR+G+ +  R K 
Sbjct: 125 ILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKA 184

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           F  N+L++D   ++  +E+ +G +    L  +L   D V ++  L E    + N   + +
Sbjct: 185 FGFNVLFYDP-YLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQ 243

Query: 556 MKKGVIIVNNARGAIMD 606
           M++G  +VN ARG ++D
Sbjct: 244 MRQGAFLVNTARGGLVD 260

---

>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 554

 Score = 90.1 bits (222), Expect = 5e-18
 Identities = 57/187 (30%), Positives = 93/187 (49%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           VT + I+    L+++  AG+G D+ID+P     G+ V      NT++ AE  L  ++ L 
Sbjct: 81  VTEKIIQAGSQLKIIGRAGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALA 140

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R+     + V + +W          ++  KT+G VG G+IG  +    K     LL +D 
Sbjct: 141 RHIPDANKSVKESKWERKQFI--GTEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDP 198

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
             I+ E   +IG     DLD +  + D + ++ P T +T  + N E +AKMK    I+N 
Sbjct: 199 F-ISQERADQIGCTL-VDLDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINC 256

Query: 586 ARGAIMD 606
           +RG I+D
Sbjct: 257 SRGGIID 263

---

>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)|
          Length = 440

 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 54/197 (27%), Positives = 99/197 (50%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   +T E ++K K L +++  G G D+ID+      G+ V  V  ++    A+  L  
Sbjct: 76  YHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCH 135

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R     +Q + +G        +  +A  A  + G+T+G +G GR+G+ +  R K 
Sbjct: 136 ILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKA 195

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           F  N+L++D   ++  +E+ +G +    L  +L   D V ++  L E    + N   + +
Sbjct: 196 FGFNVLFYDP-YLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQ 254

Query: 556 MKKGVIIVNNARGAIMD 606
           M++G  +VN ARG ++D
Sbjct: 255 MRQGAFLVNTARGGLVD 271

---

>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate
           dehydrogenase) (Glyoxylate reductase) (HPR-A)
          Length = 313

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 51/189 (26%), Positives = 94/189 (49%), Gaps = 4/189 (2%)
 Frame = +1

Query: 52  AERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRN 231
           A+ +K+  +L+L+  A  G+D +D       G+TV  +      +V E  +  +  L R 
Sbjct: 56  ADTLKQLPDLKLIAVAATGTDVVDKAAAKAQGITVVNIRNYAFNTVPEHVVGLMFALRRA 115

Query: 232 FLPGYQQVVKGEWNVAG----IAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYH 399
            +P    V +G+WN +       +  YD+ G T+G +G G +G+ + +R +     +L  
Sbjct: 116 IVPYANSVRRGDWNKSKQFCYFDYPIYDIAGSTLGIIGYGALGKSIAKRAEALGMKVLAF 175

Query: 400 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIV 579
           D    +  +          DL+ +L + DV+ ++ PLT  T+ M   E++ KMK+  I++
Sbjct: 176 DVFPQDGLV----------DLETILTQSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILI 225

Query: 580 NNARGAIMD 606
           N ARG ++D
Sbjct: 226 NTARGGLVD 234

---

>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 324

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 2/189 (1%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V A  ++K   L    T  +G D+ D+       + +       T +VA+  +  +L   
Sbjct: 56  VNAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTA 115

Query: 226 RNFLPGYQQVVKGEWNVA-GIAHRAYDLEGKTVGTVGAGRIGRLLLQRLK-PFNCNLLYH 399
           R  +   ++V  GEW  + G      D+  KT+G VG GRIG  L QR    FN  +LY+
Sbjct: 116 RRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYN 175

Query: 400 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIV 579
            R   + E E+   A++  DLD +L + D V +  PLT++T  +F  E+ AKMK   I +
Sbjct: 176 ARRH-HKEAEERFNARYC-DLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFI 233

Query: 580 NNARGAIMD 606
           N  RG ++D
Sbjct: 234 NAGRGPVVD 242

---

>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)|
          Length = 440

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 53/197 (26%), Positives = 98/197 (49%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   +T E ++K K L +++  G G D+ID+      G+ V  V  ++    A+  +  
Sbjct: 76  YHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTMCH 135

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R     +Q + +G        +  +A  A  + G+T+G +G GR+G+ +  R K 
Sbjct: 136 ILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKT 195

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           F  N+ ++D   ++  +E+ +G +    L  +L   D V ++  L E    + N   I +
Sbjct: 196 FGFNVFFYDPY-LSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTIKQ 254

Query: 556 MKKGVIIVNNARGAIMD 606
           M++G  +VN ARG ++D
Sbjct: 255 MRQGAFLVNTARGGLVD 271

---

>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)|
           (XCtBP)
          Length = 437

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 52/197 (26%), Positives = 98/197 (49%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   ++ E ++K K L +++  G G D+ID+      G+ V  +  ++    A+  L  
Sbjct: 79  YHTITLSREDLEKFKALRIIIKIGSGYDNIDIKSAAELGIAVCNIPSASVEETADSTLCH 138

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R     +Q + +G        +  +A  A  + G+T+G +G GRIG+ +  R K 
Sbjct: 139 ILNLYRRVTWLHQAMREGNRPASVEQIREVAGGAARIRGETLGIIGLGRIGQAVALRAKA 198

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           FN  ++++D   +   +E+ +G +    L  +L   D + ++  L E    + N   I +
Sbjct: 199 FNFTVIFYDPY-LADGVERSLGLQRMATLQELLMHSDCITLHCNLNEHNHHLINDFTIKQ 257

Query: 556 MKKGVIIVNNARGAIMD 606
           M++G  +VN ARG ++D
Sbjct: 258 MRQGCFLVNTARGGLVD 274

---

>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 324

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 60/189 (31%), Positives = 93/189 (49%), Gaps = 2/189 (1%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V A  ++K   L    T  +G D+ D+       + +       T +VA+  +  +L   
Sbjct: 56  VDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTA 115

Query: 226 RNFLPGYQQVVKGEWNVA-GIAHRAYDLEGKTVGTVGAGRIGRLLLQRLK-PFNCNLLYH 399
           R  +   ++V  GEW  + G      D+  KT+G VG GRIG  L QR    FN  +LY+
Sbjct: 116 RRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYN 175

Query: 400 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIV 579
            R   + E E+   A++  DLD +L + D V +  PLT++T  +F  E+ AKMK   I +
Sbjct: 176 ARRH-HKEAEERFNARYC-DLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFI 233

Query: 580 NNARGAIMD 606
           N  RG ++D
Sbjct: 234 NAGRGPVVD 242

---

>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)|
           (Vancomycin B-type resistance protein vanHB)
          Length = 323

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 54/177 (30%), Positives = 94/177 (53%)
 Frame = +1

Query: 79  LELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVV 258
           ++ + T  IG +HID       G++V  V  S   SVA+  LM +L+ +R        V 
Sbjct: 73  VKYISTRSIGCNHIDTTAAERMGISVGTVAYSPD-SVADYALMLMLMAIRGAKSTIHAVA 131

Query: 259 KGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEI 438
           +  + +  +  R  +L   TVG +G G IG+ +++RL+ F C +L +D         ++I
Sbjct: 132 QQNFRLDCV--RGKELRDMTVGVIGTGHIGQAVVKRLRGFGCRVLAYDN-------SRKI 182

Query: 439 GAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
            A + + LD +L   D+V ++ PL   TR +  + +I +MK+G  ++N  RGA++DT
Sbjct: 183 EADYVQ-LDELLKNSDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDT 238

---

>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor|
           (EC 1.1.1.95) (3-PGDH)
          Length = 624

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 58/191 (30%), Positives = 93/191 (48%), Gaps = 4/191 (2%)
 Frame = +1

Query: 46  VTAERIKKAKN-LELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILIL 222
           VT E  + AK  L+++  AG+G D++DL      G  V     +NTV+ AE  +  +  +
Sbjct: 134 VTREVFEAAKGRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASM 193

Query: 223 LRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD 402
            RN       +  G+W  +   +    L GKT+  +G G++G  + +R K     ++ HD
Sbjct: 194 ARNVAQADASIKAGKWERS--KYVGVSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHD 251

Query: 403 RLQINPELEKEIGAKFEEDL---DAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
                P    +       DL   D  +   D V ++ PLT  T+ +FN E  +KMKKGV 
Sbjct: 252 -----PYAPADRARALGVDLVSFDQAISTADFVSLHMPLTPATKKVFNDETFSKMKKGVR 306

Query: 574 IVNNARGAIMD 606
           ++N ARG ++D
Sbjct: 307 LINVARGGVID 317

---

>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate
           dehydrogenase) (Glyoxylate reductase)
          Length = 321

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 1/179 (0%)
 Frame = +1

Query: 73  KNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQ 252
           +N++ + T  IG DHIDL      G+ V       TV+ AE  ++ +L   R    G + 
Sbjct: 67  ENIKCISTYSIGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAGEGEKM 126

Query: 253 VVKGEW-NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELE 429
           +    W     +      L+ KT+G  G G IG+ L +R + F+ ++ Y D  + +   E
Sbjct: 127 IRTRSWPGWEPLELVGEKLDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHRASSSDE 186

Query: 430 KEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
               A F + LD++L       +N P T +TR  FNK  I  + +G I+VN ARG ++D
Sbjct: 187 ASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVD 245

---

>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH|
           1)
          Length = 469

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 58/188 (30%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           +T+  ++ AKNL  +    IG++ +DL      G+ V     SN+ SVAE  +  I+ L 
Sbjct: 112 LTSNVLQHAKNLVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLA 171

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R       ++  G WN   +A R +++ GKT+G +G G IG  L    +    ++LY+D 
Sbjct: 172 RQLGDRSIELHTGTWNK--VAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDI 229

Query: 406 LQINPELEKEIG-AKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVN 582
           + I       +G A+    LD +L K D V ++ P T +T  M +  + A MK G  ++N
Sbjct: 230 VTI-----MALGTARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVIN 284

Query: 583 NARGAIMD 606
            +RG ++D
Sbjct: 285 ASRGTVVD 292

---

>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)|
           (Vancomycin resistance protein vanH)
          Length = 322

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 56/181 (30%), Positives = 93/181 (51%)
 Frame = +1

Query: 67  KAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGY 246
           K   ++ + T  IG +HID       G+TV  V  S   SVA+  +M IL+ +RN     
Sbjct: 68  KRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAYSPD-SVADYTMMLILMAVRNVKSIV 126

Query: 247 QQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPEL 426
           + V K ++ +   + R   L   TVG VG G+IG+ +++RL+ F C +L + R       
Sbjct: 127 RSVEKHDFRLD--SDRGKVLSDMTVGVVGTGQIGKAVIERLRGFGCKVLAYSR------- 177

Query: 427 EKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
            + I   +    D +L   D+V ++ PL   T  + + E+I +MK+G  ++N  RG ++D
Sbjct: 178 SRSIEVNYVP-FDELLQNSDIVTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVD 236

Query: 607 T 609
           T
Sbjct: 237 T 237

---

>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)|
          Length = 476

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 58/197 (29%), Positives = 95/197 (48%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   +T E ++K K L +++  G G+D+ID+      G+ V  V G     VA+  +  
Sbjct: 76  WHTIILTKEDLEKFKALRIIVRIGSGTDNIDVKAAGELGIAVCNVPGYGVEEVADTTMCL 135

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R        V +G+       V   AH    + G T+G VG GRIG  +  R K 
Sbjct: 136 ILNLYRRTYWLANMVREGKKFTGPEQVREAAHGCARIRGDTLGLVGLGRIGSAVALRAKA 195

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           F  N++++D   +   ++K +G      L  +L + D V ++  L E    + N+  I +
Sbjct: 196 FGFNVIFYDP-YLPDGIDKSLGLTRVYTLQDLLFQSDCVSLHCTLNEHNHHLINEFTIKQ 254

Query: 556 MKKGVIIVNNARGAIMD 606
           M+ G  +VN ARG ++D
Sbjct: 255 MRPGAFLVNTARGGLVD 271

---

>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)|
          Length = 331

 Score = 85.9 bits (211), Expect = 9e-17
 Identities = 57/189 (30%), Positives = 99/189 (52%), Gaps = 9/189 (4%)
 Frame = +1

Query: 70  AKNLELLLTAGI--------GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           A+ LE+L   GI        G +++DL       + V  V   +  SVAE  +  +L L 
Sbjct: 58  AEVLEILAGLGIKLVALRCAGYNNVDLDAAKKLNIKVVRVPAYSPYSVAEYAVGMLLTLN 117

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP-FNCNLLYHD 402
           R    G ++V +  +++ G+     D+  KTVG +G G IG +    +   F  N++ + 
Sbjct: 118 RQISRGLKRVRENNFSLEGLI--GLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAY- 174

Query: 403 RLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVN 582
           +   +PEL K++G +F   LD ++   D++ ++ PLT +   M N+E +A+ KKG  +VN
Sbjct: 175 KPHPDPELAKKVGFRFTS-LDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLVN 233

Query: 583 NARGAIMDT 609
            +RG ++DT
Sbjct: 234 TSRGGLVDT 242

---

>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH|
           2)
          Length = 469

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 57/188 (30%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           +T + ++ A+NL  +    IG++ +DL      G+ V     SN+ SVAE  +  I+ L 
Sbjct: 112 LTEKILQHARNLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLA 171

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R       ++  G WN   +A R +++ GKT+G +G G IG  L    +    ++LY+D 
Sbjct: 172 RQLGDRSIELHTGTWNK--VAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDI 229

Query: 406 LQINPELEKEIG-AKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVN 582
           + I       +G A+    LD +L K D V ++ P T +T  M +  + A MK G  ++N
Sbjct: 230 VTI-----MALGTARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVIN 284

Query: 583 NARGAIMD 606
            +RG ++D
Sbjct: 285 ASRGTVVD 292

---

>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 332

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 58/192 (30%), Positives = 99/192 (51%), Gaps = 5/192 (2%)
 Frame = +1

Query: 49  TAERIKK-----AKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRI 213
           TAE + K      KN+ L     +G D++D+P     GL ++ V   +  ++AE  + ++
Sbjct: 58  TAEVLNKLADEGVKNISL---RNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114

Query: 214 LILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLL 393
           + LLR      +++ K ++  A     A +L   TVG +G GRIGR  +   K F   ++
Sbjct: 115 MQLLRQTPMFNKKLAKQDFRWA--PDIAKELNTMTVGVIGTGRIGRAAIDIFKGFGAKVI 172

Query: 394 YHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
            +D  + N ELEKE    + + LD +  + DV+ ++ P  +    M N +  +KMK G  
Sbjct: 173 GYDVYR-NAELEKE--GMYVDTLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAY 229

Query: 574 IVNNARGAIMDT 609
           I+N ARG ++D+
Sbjct: 230 ILNFARGTLIDS 241

---

>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)|
          Length = 332

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 58/192 (30%), Positives = 99/192 (51%), Gaps = 5/192 (2%)
 Frame = +1

Query: 49  TAERIKK-----AKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRI 213
           TAE + K      KN+ L     +G D++D+P     GL ++ V   +  ++AE  + ++
Sbjct: 58  TAEVLNKLADEGVKNISL---RNVGVDNLDVPTVKARGLNISNVPAYSPNAIAELSVTQL 114

Query: 214 LILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLL 393
           + LLR      +++ K ++  A     A +L   TVG +G GRIGR  +   K F   ++
Sbjct: 115 MQLLRQTPLFNKKLAKQDFRWA--PDIAKELNTMTVGVIGTGRIGRAAIDIFKGFGAKVI 172

Query: 394 YHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
            +D  + N ELEKE    + + LD +  + DV+ ++ P  +    M N +  +KMK G  
Sbjct: 173 GYDVYR-NAELEKE--GMYVDTLDELYAQADVITLHVPALKDNYHMLNADAFSKMKDGAY 229

Query: 574 IVNNARGAIMDT 609
           I+N ARG ++D+
Sbjct: 230 ILNFARGTLIDS 241

---

>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)|
           (Fermentative lactate dehydrogenase)
          Length = 329

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 52/168 (30%), Positives = 88/168 (52%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G +++DL      GL V  V   +  +VAE  +  ++ L R     YQ+     +++ G+
Sbjct: 78  GFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGL 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
               + + GKT G +G G+IG  +L+ LK F   LL  D       LE  +G ++  DL 
Sbjct: 138 T--GFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAAALE--LGVEYV-DLP 192

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
            +  + DV+ ++ PLT +   + N+    +MK GV+IVN +RGA++D+
Sbjct: 193 TLFSESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDS 240

---

>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)|
          Length = 445

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 51/197 (25%), Positives = 97/197 (49%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   +T E ++K K L +++  G G D++D+      G+ V  +  +     A+  +  
Sbjct: 82  YHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICH 141

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R     YQ + +G        +  +A  A  + G+T+G +G GR G+ +  R K 
Sbjct: 142 ILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKA 201

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           F  +++++D   +   +E+ +G +    L  +L + D V ++  L E    + N   I +
Sbjct: 202 FGFSVIFYDPY-LQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQ 260

Query: 556 MKKGVIIVNNARGAIMD 606
           M++G  +VN ARG ++D
Sbjct: 261 MRQGAFLVNAARGGLVD 277

---

>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)|
          Length = 445

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 51/197 (25%), Positives = 97/197 (49%), Gaps = 5/197 (2%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           +H   +T E ++K K L +++  G G D++D+      G+ V  +  +     A+  +  
Sbjct: 82  YHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCH 141

Query: 211 ILILLRNFLPGYQQVVKGEW-----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP 375
           IL L R     YQ + +G        +  +A  A  + G+T+G +G GR G+ +  R K 
Sbjct: 142 ILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKA 201

Query: 376 FNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK 555
           F  +++++D   +   +E+ +G +    L  +L + D V ++  L E    + N   I +
Sbjct: 202 FGFSVIFYDPY-LQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQ 260

Query: 556 MKKGVIIVNNARGAIMD 606
           M++G  +VN ARG ++D
Sbjct: 261 MRQGAFLVNAARGGLVD 277

---

>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC|
           1.1.1.79)
          Length = 328

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 1/178 (0%)
 Frame = +1

Query: 76  NLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQV 255
           NL ++ T  +G DH+ L      G+ V    G  T + AE  +  +L   R      ++V
Sbjct: 74  NLRVISTLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEV 133

Query: 256 VKGEWNV-AGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEK 432
             G W+  + +    Y L   TVG VG GRIG+ + +RLKPF      +   Q  P+   
Sbjct: 134 KNGGWSSWSPLWMCGYGLSQSTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRPQEAA 193

Query: 433 EIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           E  A+F   +  +  + D +V++  LT  T G+ +K+   KMK   I +N +RG +++
Sbjct: 194 EFQAEF-VPIAQLAAESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVN 250

---

>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
           (2-ketoaldonate reductase)
          Length = 323

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 55/173 (31%), Positives = 89/173 (51%), Gaps = 2/173 (1%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           T  +G D+ D+      G+ + +     T +VA+  +  +L   R  +   ++V  GEW 
Sbjct: 71  TISVGYDNFDVEALNQRGIVLIDTPTVLTETVADTMMALVLSSARRVVEVAERVKAGEWR 130

Query: 274 VA-GIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKP-FNCNLLYHDRLQINPELEKEIGAK 447
            + G      D+  K +G +G GRIG  L QR    F   +LY+ R   + E E    A+
Sbjct: 131 RSIGPDWFGIDVHHKKMGILGMGRIGLALAQRAHHGFGMPILYNARKH-HEEAESRFNAQ 189

Query: 448 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           +  DLD +L + D + I+ PLTE+T  M  +E++AKMK   I++N  RG ++D
Sbjct: 190 YC-DLDTLLRESDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVD 241

---

>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)|
           (3-PGDH)
          Length = 466

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 53/188 (28%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           +T   ++ A +L ++    IG++ +DL      G+ V     +N+ SVAE  +  I+ L 
Sbjct: 109 LTRRVLEAADSLIVIGCFCIGTNQVDLDFAAERGIAVFNSPYANSRSVAELVIGYIISLA 168

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R       ++ +GEWN   ++   +++ GKT+G +G G IG  L    +    +++Y+D 
Sbjct: 169 RQVGDRSLELHRGEWNK--VSSGCWEIRGKTLGIIGYGHIGSQLSVLAEAMGLHVVYYDI 226

Query: 406 LQINPELEKEIG-AKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVN 582
           L I P     +G AK    L  +L + D V ++ P + +T+ M + ++ A MK+G  ++N
Sbjct: 227 LPIMP-----LGSAKQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLIN 281

Query: 583 NARGAIMD 606
            +RG ++D
Sbjct: 282 ASRGTVVD 289

---

>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC|
           1.1.1.79)
          Length = 328

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 1/178 (0%)
 Frame = +1

Query: 76  NLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQV 255
           NL+++ T  +G DH+ L      G+ V       T + AE  +  +L   R      ++V
Sbjct: 74  NLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEV 133

Query: 256 VKGEWNV-AGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEK 432
             G W     +    Y L   TVG +G GRIG+ + +RLKPF      +   Q  PE   
Sbjct: 134 KNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193

Query: 433 EIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           E  A+F    + +  + D +V+   LT  T G+ NK+   KMK+  + +N +RG +++
Sbjct: 194 EFQAEFVSTPE-LAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVN 250

---

>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 391

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 54/186 (29%), Positives = 85/186 (45%), Gaps = 4/186 (2%)
 Frame = +1

Query: 61  IKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLP 240
           I KA  L+ + TA  G DH+D       G+T     G N V VAE  L  ++++      
Sbjct: 54  ISKANKLQFVGTATAGQDHVDQALLAERGITFTSAPGCNKVGVAEYVLSALMVI------ 107

Query: 241 GYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP 420
           G QQ               + +  KT+G +GAG +G  L Q L       L +D     P
Sbjct: 108 GQQQ--------------GFSIFDKTIGIIGAGNVGSYLAQCLDALGIPYLLND-----P 148

Query: 421 ELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNA 588
             E+E   +    L+A+  +CDV+ ++TP+T+     T  + N+  I  ++   I++N A
Sbjct: 149 IKEQEGDTRQFHSLEAIKAQCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAA 208

Query: 589 RGAIMD 606
           RG + D
Sbjct: 209 RGPVTD 214

---

>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)|
          Length = 325

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 58/199 (29%), Positives = 96/199 (48%), Gaps = 2/199 (1%)
 Frame = +1

Query: 16  LITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAE 195
           L+T+      +  E ++ A  L+++    +G D+ D+      G+       +   +VA+
Sbjct: 49  LLTSGTSGPSINRELLEHAPKLKVVSNQSVGYDNFDIEAMKERGVVGTHTPYTLDDTVAD 108

Query: 196 DELMRILILLRNFLPGYQQVVKGEWN-VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLK 372
                IL   R      + V  G+W  V   A    D+  +T+G +G GRIG    +R K
Sbjct: 109 LAFSLILSSARRVAELDRFVRAGKWGTVEEEALFGIDVHHQTLGIIGMGRIGEQAARRAK 168

Query: 373 -PFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKI 549
             F+  +LYH+R +   E E  IG K+ E LD +L + D +++ TPLT++T  M  + + 
Sbjct: 169 FGFDMEVLYHNRHR-KQETEDSIGVKYAE-LDTLLEQSDFILLITPLTDETYHMIGEREF 226

Query: 550 AKMKKGVIIVNNARGAIMD 606
             MK   I VN +RG  +D
Sbjct: 227 KLMKNSAIFVNISRGKTVD 245

---

>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 48/168 (28%), Positives = 86/168 (51%)
 Frame = +1

Query: 103 IGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 282
           +G+D+ID          ++ V   +  ++AE  ++++  LLR       ++ K +   A 
Sbjct: 78  VGTDNIDFDAAREFNFNISNVPVYSPNAIAEHSMLQLSRLLRRTKALDAKIAKRDLRWAP 137

Query: 283 IAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDL 462
              R  ++  +TVG +G G IGR+ +  LK F   ++ +D+   N EL+ E    + + L
Sbjct: 138 TTGR--EMRMQTVGVIGTGHIGRVAINILKGFGAKVIAYDKYP-NAELQAE--GLYVDTL 192

Query: 463 DAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           D +  + D + +  P   +   + N + IAKMK GV+I+N ARG +MD
Sbjct: 193 DELYAQADAISLYVPGVPENHHLINADAIAKMKDGVVIMNAARGNLMD 240

---

>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 332

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 49/169 (28%), Positives = 89/169 (52%)
 Frame = +1

Query: 103 IGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 282
           +G D+ID+      G  +  V   +  ++AE   ++   +LR      ++V + +   A 
Sbjct: 78  VGVDNIDMAKAKELGFQITNVPVYSPNAIAEHAAIQAARILRQAKAMDEKVARHDLRWAP 137

Query: 283 IAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDL 462
              R  ++  + VG VG G IG++ +Q ++ F   ++ +D  + NPELEK+    + + L
Sbjct: 138 TIGR--EVRDQVVGVVGTGHIGQVFMQIMEGFGAKVIAYDIFR-NPELEKK--GYYVDSL 192

Query: 463 DAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
           D +  + DV+ ++ P       M N + IAKMK+ V+IVN +RG ++DT
Sbjct: 193 DDLYKQADVISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVDT 241

---

>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 336

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 53/188 (28%), Positives = 95/188 (50%), Gaps = 8/188 (4%)
 Frame = +1

Query: 70  AKNLELLLTAGI--------GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           A  L+ L  AG+        G D+ID+      G  +  V   +  ++AE   ++   +L
Sbjct: 59  ADTLQALADAGVTKMSLRNVGVDNIDMDKAKELGFQITNVPVYSPNAIAEHAAIQAARVL 118

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           R      +++ K +   A    R  ++  + VG VG G IG++ ++ ++ F   ++ +D 
Sbjct: 119 RQDKRMDEKMAKRDLRWAPTIGR--EVRDQVVGVVGTGHIGQVFMRIMEGFGAKVIAYDI 176

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
            + NPELEK+    + + LD +  + DV+ ++ P       M N + IA+MK GV+IVN 
Sbjct: 177 FK-NPELEKK--GYYVDSLDDLYKQADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNC 233

Query: 586 ARGAIMDT 609
           +RG ++DT
Sbjct: 234 SRGRLVDT 241

---

>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)|
          Length = 315

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 46/189 (24%), Positives = 93/189 (49%), Gaps = 5/189 (2%)
 Frame = +1

Query: 55  ERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNF 234
           E +++   L+L+     G++++DL      G+ V  VTG ++ +V E  ++ ++  L++ 
Sbjct: 57  ETLQQLPKLKLIAITATGTNNVDLVAAEEMGIAVRNVTGYSSTTVPE-HVIGLIFSLKHS 115

Query: 235 LPGY-QQVVKGEW----NVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYH 399
           L G+ +   + +W          +   D+ G T+G  G G +G  + +        +LY 
Sbjct: 116 LAGWLRDQTEAKWAESKQFCYFDYPITDVRGSTLGVFGKGCLGTEVGRLANAVGMKVLYA 175

Query: 400 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIV 579
           +        +  +  +     D +L + D+V ++ PLTE T+ + N E ++KMKKG  ++
Sbjct: 176 EHK------DATVCREGYTPFDEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAFLI 229

Query: 580 NNARGAIMD 606
           N  RG ++D
Sbjct: 230 NTGRGPLID 238

---

>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 3/191 (1%)
 Frame = +1

Query: 43  YVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILIL 222
           ++T + I  A+ L  +    IG++ +DL      G+ V     SNT SVAE  +  +L+L
Sbjct: 63  HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 122

Query: 223 LRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD 402
           LR       +  +G WN   +A  +++  GK +G +G G IG  L    +     + ++D
Sbjct: 123 LRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD 180

Query: 403 RLQINPELEKEI---GAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
                  +E ++    A   + L  +L   DVV ++ P    T+ M   ++I+ MK G +
Sbjct: 181 -------IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 233

Query: 574 IVNNARGAIMD 606
           ++N +RG ++D
Sbjct: 234 LINASRGTVVD 244

---

>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 3/191 (1%)
 Frame = +1

Query: 43  YVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILIL 222
           ++T + I  A+ L  +    IG++ +DL      G+ V     SNT SVAE  +  +L+L
Sbjct: 63  HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 122

Query: 223 LRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD 402
           LR       +  +G WN   +A  +++  GK +G +G G IG  L    +     + ++D
Sbjct: 123 LRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD 180

Query: 403 RLQINPELEKEI---GAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
                  +E ++    A   + L  +L   DVV ++ P    T+ M   ++I+ MK G +
Sbjct: 181 -------IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 233

Query: 574 IVNNARGAIMD 606
           ++N +RG ++D
Sbjct: 234 LINASRGTVVD 244

---

>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 3/191 (1%)
 Frame = +1

Query: 43  YVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILIL 222
           ++T + I  A+ L  +    IG++ +DL      G+ V     SNT SVAE  +  +L+L
Sbjct: 63  HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 122

Query: 223 LRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD 402
           LR       +  +G WN   +A  +++  GK +G +G G IG  L    +     + ++D
Sbjct: 123 LRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD 180

Query: 403 RLQINPELEKEI---GAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
                  +E ++    A   + L  +L   DVV ++ P    T+ M   ++I+ MK G +
Sbjct: 181 -------IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 233

Query: 574 IVNNARGAIMD 606
           ++N +RG ++D
Sbjct: 234 LINASRGTVVD 244

---

>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)|
          Length = 409

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 3/191 (1%)
 Frame = +1

Query: 43  YVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILIL 222
           ++T + I  A+ L  +    IG++ +DL      G+ V     SNT SVAE  +  +L+L
Sbjct: 63  HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 122

Query: 223 LRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD 402
           LR       +  +G WN   +A  +++  GK +G +G G IG  L    +     + ++D
Sbjct: 123 LRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD 180

Query: 403 RLQINPELEKEI---GAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
                  +E ++    A   + L  +L   DVV ++ P    T+ M   ++I+ MK G +
Sbjct: 181 -------IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 233

Query: 574 IVNNARGAIMD 606
           ++N +RG ++D
Sbjct: 234 LINASRGTVVD 244

---

>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 53/191 (27%), Positives = 86/191 (45%), Gaps = 4/191 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V A  I KA  L+ + TA  G DH+D       G+      G N V VAE     +++L 
Sbjct: 49  VNAALISKASKLKFVGTATAGMDHVDQALLKEKGIYFTAAPGCNKVGVAEYVFSVMMVLA 108

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           +                     + + +  +TVG VGAG++G  L Q L+     +L +D 
Sbjct: 109 Q--------------------QQGFSVFEQTVGIVGAGQVGSYLQQCLQGIGIKVLINDP 148

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVI 573
            +     E+E        LD +L + DV+ ++TP+T      T  + NKE +  ++   I
Sbjct: 149 FKQEEGDEREF-----TSLDRLLQEADVITLHTPITRDGKYPTHHLINKEILNSLRADQI 203

Query: 574 IVNNARGAIMD 606
           ++N ARG ++D
Sbjct: 204 LINAARGPVVD 214

---

>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)|
           (D-HICDH)
          Length = 333

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 55/204 (26%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
 Frame = +1

Query: 1   EDMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNT 180
           + ++ L TTP+  A    E++  A  ++ L    +G+D+ID+      G+ ++ V   + 
Sbjct: 46  DGINSLQTTPY--AAGVFEKMH-AYGIKFLTIRNVGTDNIDMTAMKQYGIRLSNVPAYSP 102

Query: 181 VSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLL 360
            ++AE  L   L LLRN      Q+  G++  AG      +L  +TVG +G G IG++ +
Sbjct: 103 AAIAEFALTDTLYLLRNMGKVQAQLQAGDYEKAG-TFIGKELGQQTVGVMGTGHIGQVAI 161

Query: 361 QRLKPFNCNLLYHDRLQINPELEKEIGAKFE-EDLDAMLPKCDVVVINTPLTEKTRGMFN 537
           +  K F   ++ +D     P   K     F+   L+ +  + DV+ ++ P  E+   + N
Sbjct: 162 KLFKGFGAKVIAYD-----PYPMKGDHPDFDYVSLEDLFKQSDVIDLHVPGIEQNTHIIN 216

Query: 538 KEKIAKMKKGVIIVNNARGAIMDT 609
           +     MK G I++N AR  ++DT
Sbjct: 217 EAAFNLMKPGAIVINTARPNLIDT 240

---

>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 43/169 (25%), Positives = 84/169 (49%)
 Frame = +1

Query: 103 IGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 282
           +G D++         + ++ V   +  ++AE  + ++L LLR       ++  G++    
Sbjct: 77  VGLDNVPADALKKNDIKISNVPAYSPRAIAELSVTQLLALLRKIPEFEYKMAHGDYRWE- 135

Query: 283 IAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDL 462
                 +L   TVG +G GRIGR  +   KPF   ++ +D  + NP LEKE    + + L
Sbjct: 136 -PDIGLELNQMTVGVIGTGRIGRAAIDIFKPFGAKVIAYDVFR-NPALEKE--GMYVDTL 191

Query: 463 DAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
           + +  + +V+ ++ P  +    M +++   +M+ G  I+N ARG ++DT
Sbjct: 192 EELYQQANVITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDT 240

---

>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 51/191 (26%), Positives = 86/191 (45%), Gaps = 4/191 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V A  I KA  L+ + TA  G DH+D       G+      G N V VAE     +++L 
Sbjct: 49  VNAALISKANKLKFVGTATAGMDHVDQALLKEKGIYFTAAPGCNKVGVAEYVFSVMMVLA 108

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           +                     + + +  +TVG +GAG++G  L Q L+     +L +D 
Sbjct: 109 Q--------------------QQGFSVFEQTVGIIGAGQVGSYLQQCLQGIGIKVLINDP 148

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVI 573
            +     E+E        LD +L + DV+ ++TP+T      T  + N+E +  ++   I
Sbjct: 149 FKQEEGDEREF-----TSLDRLLQEADVITLHTPITRDGKYPTHHLINEEILNSLRADQI 203

Query: 574 IVNNARGAIMD 606
           ++N ARG ++D
Sbjct: 204 LINAARGPVVD 214

---

>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 50/192 (26%), Positives = 89/192 (46%), Gaps = 5/192 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V AE I KA  L+ + TA  G DH+D       G+      G N V VAE     +++L 
Sbjct: 49  VNAELISKANKLKFVGTATAGMDHVDQALLKEKGIFFTAAPGCNKVGVAEYAFSVMMVLA 108

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
           +                     + + +  KTVG +GAG++G  L + LK    N+L    
Sbjct: 109 Q--------------------QQGFSVFDKTVGIIGAGQVGSYLEKCLKGMGINVL---- 144

Query: 406 LQINPELEKEIG-AKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGV 570
             IN   ++E G  +    L  ++ + D++ ++TP+T+     T  + +++ +  ++   
Sbjct: 145 --INDPFKQEAGDPRSFTPLAELIEQSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQ 202

Query: 571 IIVNNARGAIMD 606
           I++N ARG ++D
Sbjct: 203 ILINAARGPVVD 214

---

>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 376

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 48/191 (25%), Positives = 85/191 (44%), Gaps = 4/191 (2%)
 Frame = +1

Query: 46  VTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILL 225
           V A  ++  + L+ + +A IG+DH+DL      G+  +   G N  +V E   + +L L 
Sbjct: 49  VNAALLEANQKLKFVGSATIGTDHVDLAYLATRGIVFSNAPGCNATAVGEFAFIAMLELA 108

Query: 226 RNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDR 405
             F                       L GK VG VGAG  G    + L+ F   +L +D 
Sbjct: 109 ARF--------------------NSPLRGKVVGIVGAGNTGSATAKCLEAFGIKVLLND- 147

Query: 406 LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLT----EKTRGMFNKEKIAKMKKGVI 573
               P  E E   +    L+ +L + D++ ++ P+T     KT  +F++ ++  +K  + 
Sbjct: 148 ----PIKEAEGDPRDFVSLETLLQEADIISLHVPITRTGEHKTLHLFDEARLMSLKANIW 203

Query: 574 IVNNARGAIMD 606
           ++N  RG ++D
Sbjct: 204 LINCCRGDVID 214

---

>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent|
           phosphite dehydrogenase)
          Length = 336

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 48/192 (25%), Positives = 88/192 (45%)
 Frame = +1

Query: 31  FHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMR 210
           F P  V A+ ++    L ++  A  G D+ D+      G+ +  V    TV  AE  +  
Sbjct: 52  FMPDRVDADFLQACPELRVVGCALKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGL 111

Query: 211 ILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNL 390
            + L R+       V  GE+           L+  TVG +G G IG  +  RL+ +   L
Sbjct: 112 AVGLGRHLRAADAFVRSGEFQGWQPQFYGTGLDNATVGILGMGAIGLAMADRLQGWGATL 171

Query: 391 LYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGV 570
            YH+   ++ + E+ +G + +     +    D +++  PL   T+ + N E +A ++ G 
Sbjct: 172 QYHEAKALDTQTEQRLGLR-QVACSELFASSDFILLALPLNADTQHLVNAELLALVRPGA 230

Query: 571 IIVNNARGAIMD 606
           ++VN  RG+++D
Sbjct: 231 LLVNPCRGSVVD 242

---

>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 4/188 (2%)
 Frame = +1

Query: 55  ERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNF 234
           E +   K ++ + TA  G+DH+D       G+  +   G N ++V E     +L+L    
Sbjct: 51  ESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAE-- 108

Query: 235 LPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQI 414
                                + L  +TVG VG G +GR L  RL+      L  D    
Sbjct: 109 ------------------RDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCD---- 146

Query: 415 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVN 582
            P  ++     F   LD ++ + D++  +TPL +    KT  + +++ I  +K G I++N
Sbjct: 147 PPRADRGDEGDF-RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILIN 205

Query: 583 NARGAIMD 606
             RGA++D
Sbjct: 206 ACRGAVVD 213

---

>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 4/188 (2%)
 Frame = +1

Query: 55  ERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNF 234
           E +   K ++ + TA  G+DH+D       G+  +   G N ++V E     +L+L    
Sbjct: 51  ESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAE-- 108

Query: 235 LPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQI 414
                                + L  +TVG VG G +GR L  RL+      L  D    
Sbjct: 109 ------------------RDGFSLYDRTVGIVGVGNVGRRLQARLEALGIKTLLCD---- 146

Query: 415 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVN 582
            P  ++     F   LD ++ + D++  +TPL +    KT  + +++ I  +K G I++N
Sbjct: 147 PPRADRGDEGDF-RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILIN 205

Query: 583 NARGAIMD 606
             RGA++D
Sbjct: 206 ACRGAVVD 213

---

>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 4/188 (2%)
 Frame = +1

Query: 55  ERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNF 234
           E +   K ++ + TA  G+DH+D       G+  +   G N ++V E     +L+L    
Sbjct: 51  ESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAE-- 108

Query: 235 LPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQI 414
                                + L  +TVG VG G +GR L  RL+      L  D    
Sbjct: 109 ------------------RDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCD---- 146

Query: 415 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVN 582
            P  ++     F   LD ++   D++  +TPL +    KT  + +++ I  +K G I++N
Sbjct: 147 PPRADRGDEGDF-RSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILIN 205

Query: 583 NARGAIMD 606
             RGA++D
Sbjct: 206 ACRGAVVD 213

---

>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 47/188 (25%), Positives = 82/188 (43%), Gaps = 4/188 (2%)
 Frame = +1

Query: 55  ERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNF 234
           E +   K ++ + TA  G+DH+D       G+  +   G N ++V E     +L+L    
Sbjct: 51  ESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAE-- 108

Query: 235 LPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQI 414
                                + L  +TVG VG G +GR L  RL+      L  D  + 
Sbjct: 109 ------------------RDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRA 150

Query: 415 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVN 582
           +   E +        LD ++ + D++  +TPL +    KT  + +++ I  +K G I++N
Sbjct: 151 DCGDEGDF-----RSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILIN 205

Query: 583 NARGAIMD 606
             RGA++D
Sbjct: 206 ACRGAVVD 213

---

>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 54/205 (26%), Positives = 94/205 (45%), Gaps = 4/205 (1%)
 Frame = +1

Query: 4   DMHVLITTPFHPAYVTAERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTV 183
           D  VL+     P  VT E ++ +  +  + T  IG+DH+DL       +  +   G N  
Sbjct: 37  DADVLLVRSVTP--VTREMLEGSP-VRFVGTCTIGTDHLDLAYFQDAAIQWSSAPGCNAR 93

Query: 184 SVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQ 363
            V +  L  +L L                 + G+     DL  +T G VGAG++G  L+ 
Sbjct: 94  GVVDYVLGSLLTLAE---------------IEGV-----DLRQRTYGVVGAGQVGGRLIA 133

Query: 364 RLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEK----TRGM 531
            LK     +L  D     P  +   G  F   LD +L +CDV+ ++TPL +     T  +
Sbjct: 134 VLKALGWKVLVCD-----PPRQSAEGGDFVS-LDEILQRCDVISLHTPLDKSGQSPTWHL 187

Query: 532 FNKEKIAKMKKGVIIVNNARGAIMD 606
            ++ ++ ++++G  ++N +RGA++D
Sbjct: 188 LDEARLRQLRQGAWLINASRGAVVD 212

---

>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 381

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 4/186 (2%)
 Frame = +1

Query: 61  IKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLP 240
           + KA  L+ + TA  G DH+D       G+      G N V VAE     +++L +    
Sbjct: 54  LAKANRLKFVGTATAGMDHVDQALLRERGIFFTAAPGCNKVGVAEYVFSVLMVLAQ---- 109

Query: 241 GYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP 420
                            + + +  KTVG +GAG++G  L + L      +L +D     P
Sbjct: 110 ----------------QQGFSVFDKTVGIIGAGQVGSYLAKCLSGIGMKVLLND-----P 148

Query: 421 ELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNA 588
             + +   +   +L+ +L + DV+ ++TP+T      T  + +   + +++   I++N A
Sbjct: 149 PKQAQGDEREFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAA 208

Query: 589 RGAIMD 606
           RG ++D
Sbjct: 209 RGPVVD 214

---

>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent|
           hydroxypyruvate reductase) (HPR) (GDH)
          Length = 382

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 51/187 (27%), Positives = 87/187 (46%), Gaps = 19/187 (10%)
 Frame = +1

Query: 103 IGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAG 282
           +G +++D+      G+ V    G  T + AE      L   R  +   + +  G ++  G
Sbjct: 95  VGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYD--G 152

Query: 283 IAHRAYD---LEGKTVGTVGAGRIGRLLLQRL-KPFNCNLLYHDRLQINPELEKEIGAKF 450
                +    L+G+TVG +GAGRIG    + + + F  NL+Y D  Q +  LEK + A  
Sbjct: 153 WLPNLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQ-STRLEKFVTAYG 211

Query: 451 E---------------EDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           E                 +D +L + DV+ ++  L + T  + NKE +  MKK  I++N 
Sbjct: 212 EFLKANGEAPVTWRRASSMDEVLREADVISLHPVLDKTTFHLVNKESLKAMKKDAILINC 271

Query: 586 ARGAIMD 606
           +RG ++D
Sbjct: 272 SRGPVID 278

---

>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 44/166 (26%), Positives = 81/166 (48%)
 Frame = +1

Query: 112 DHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAH 291
           D  +L       + +  V   +  S+AE  +  +L L+R+ +   ++ VK +    G+  
Sbjct: 80  DMYNLDLATENDIIITNVPSYSPESIAEFTVTIVLNLIRH-VELIRENVKKQNFTWGLPI 138

Query: 292 RAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAM 471
           R   L   TV  +G GRIG    +  K F C ++ +D  Q   +  K +   ++E ++  
Sbjct: 139 RGRVLGDMTVAIIGTGRIGLATAKIFKGFGCKVVGYDIYQ--SDAAKAV-LDYKESVEEA 195

Query: 472 LPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
           +   D+V ++ P T +   +FN +     KKG I++N ARGA+++T
Sbjct: 196 IKDADLVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIET 241

---

>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 47/175 (26%), Positives = 80/175 (45%), Gaps = 4/175 (2%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           T  IG+DH+DL      G+  +   G N   V +  L  +L +                 
Sbjct: 64  TCTIGTDHLDLDYFAEAGIAWSSAPGCNARGVVDYVLGCLLAMAEV-------------- 109

Query: 274 VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 453
                 R  DL  +T G VGAG++G  L++ L+     +L  D     P   +E   +F 
Sbjct: 110 ------RGADLAERTYGVVGAGQVGGRLVEVLRGLGWKVLVCDP----PRQAREPDGEFV 159

Query: 454 EDLDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
             L+ +L + DV+ ++TPL       TR + ++ ++A ++ G  +VN +RGA++D
Sbjct: 160 S-LERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVD 213

---

>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 372

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 46/181 (25%), Positives = 77/181 (42%), Gaps = 4/181 (2%)
 Frame = +1

Query: 76  NLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQV 255
           +++ + T   G DHID        +      GSN VSV E     +  L +         
Sbjct: 58  SIKFIGTVTSGVDHIDQNYLKNNNIRCVSTPGSNAVSVVEYVCATLFWLAQR-------- 109

Query: 256 VKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKE 435
                         + L  KTVG +G G IG LL QRL     + L +D  +   + ++ 
Sbjct: 110 ------------DCFFLRDKTVGIIGVGNIGNLLYQRLNSLGVHTLLYDPYKSKCDTDR- 156

Query: 436 IGAKFEEDLDAMLPKCDVVVINTPLT----EKTRGMFNKEKIAKMKKGVIIVNNARGAIM 603
                 + LD ++ K D++ ++ PLT      T  M NK+ +  +    I++N +RGA++
Sbjct: 157 ---MSWKSLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVV 213

Query: 604 D 606
           +
Sbjct: 214 N 214

---

>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 2/183 (1%)
 Frame = +1

Query: 67  KAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRN--FLP 240
           K   ++ +     G D  +L      G+ ++ V   +  S+AE  +   L L+R    + 
Sbjct: 65  KEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIAEFTVTIALNLIRKVELIR 124

Query: 241 GYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP 420
              +     W    +  R   L   TV  +G GRIG    +  K F C ++ +D +  NP
Sbjct: 125 ANVREQNFSWT---LPIRGRVLGNMTVAIIGTGRIGLATAKIFKGFGCRVIGYD-IYHNP 180

Query: 421 ELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAI 600
             +  +  ++   ++  + K D+V ++ P T +   +FN +   + KKG I++N ARGA+
Sbjct: 181 MADGIL--EYVNSVEEAVEKADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGAL 238

Query: 601 MDT 609
           ++T
Sbjct: 239 VET 241

---

>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 44/183 (24%), Positives = 84/183 (45%), Gaps = 2/183 (1%)
 Frame = +1

Query: 67  KAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRN--FLP 240
           K   ++ +     G D  +L      G+ ++ V   +  S+AE  +   L L+R    + 
Sbjct: 65  KEMGIKQIAQRSAGVDMYNLELAKQHGIIISNVPSYSPESIAEFTVTIALNLIRKVELIR 124

Query: 241 GYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP 420
              +     W    +  R   L   TV  +G GRIG    +  K F C ++ +D +  NP
Sbjct: 125 ANVREQNFSWT---LPIRGRVLGNMTVAIIGTGRIGLATAKIFKGFGCRVIGYD-IYHNP 180

Query: 421 ELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAI 600
             +  +  ++   ++  + + D+V ++ P T +   +FN +   + KKG I++N ARGA+
Sbjct: 181 MADGIL--EYVNSVEEAVEEADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGAL 238

Query: 601 MDT 609
           ++T
Sbjct: 239 VET 241

---

>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 5/189 (2%)
 Frame = +1

Query: 55  ERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNF 234
           E + K  N++ + +A  G DH+D+       +      G N+V+VAE     +L      
Sbjct: 51  ENLLKNSNIKFIGSATSGKDHVDVDWLKKNKINFDFAPGCNSVAVAEYVFSSMLY----- 105

Query: 235 LPGYQQVVKGEWNVAGIAHR-AYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQ 411
                            A+R  + L  KTVG VG G IG+ L ++L       +  D   
Sbjct: 106 ----------------FAYRDKFSLLKKTVGIVGFGNIGKCLNKKLSAIGVKTILCD--- 146

Query: 412 INPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEK----TRGMFNKEKIAKMKKGVIIV 579
             P LE++   K  + L+ ++   D++ ++ PLT      T  + NK+ +  +K   I++
Sbjct: 147 --PILEEKNNIKL-KSLNEIVQNSDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILI 203

Query: 580 NNARGAIMD 606
           N +RG+++D
Sbjct: 204 NTSRGSVID 212

---

>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 4/188 (2%)
 Frame = +1

Query: 55  ERIKKAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNF 234
           E + K + ++ + TA  G+DH+D       G+  +   G N ++V E     +++L    
Sbjct: 51  EELLKGRAVKFIGTATAGTDHVDQSWLSQAGIGFSAAPGCNAIAVVEYVFSALMLLAE-- 108

Query: 235 LPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQI 414
                                ++L+ K VG VG G +G  L +RL       L  D    
Sbjct: 109 ------------------RDNFELKDKVVGIVGVGNVGSRLAERLAVLGIRTLLCD---- 146

Query: 415 NPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVN 582
            P  ++    +F   L+ ++ + D++  +TPL +    KT  + + E ++ +    I++N
Sbjct: 147 PPRADRGDAGEF-WSLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILIN 205

Query: 583 NARGAIMD 606
            +RG ++D
Sbjct: 206 ASRGEVID 213

---

>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           TA  G+DH+D       G+  +   G N ++V E     +L+L                 
Sbjct: 64  TATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAE--------------- 108

Query: 274 VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 453
                   + L  +T+G VG G +G  L  RL+      L  D     P   +     F 
Sbjct: 109 -----RDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCD----PPRAARGDEGDF- 158

Query: 454 EDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
             LD ++ + DV+  +TPL +    KT  + ++  I ++K G I++N  RG ++D
Sbjct: 159 RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVD 213

---

>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           TA  G+DH+D       G+  +   G N ++V E     +L+L                 
Sbjct: 64  TATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAE--------------- 108

Query: 274 VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 453
                   + L  +T+G VG G +G  L  RL+      L  D     P   +     F 
Sbjct: 109 -----RDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCD----PPRAARGDEGDF- 158

Query: 454 EDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
             LD ++ + DV+  +TPL +    KT  + ++  I ++K G I++N  RG ++D
Sbjct: 159 RTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVD 213

---

>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 348

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 45/187 (24%), Positives = 81/187 (43%), Gaps = 6/187 (3%)
 Frame = +1

Query: 67  KAKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILI--LLRNFLP 240
           +   ++ + TA IG DHID       G+  A   G N+ SVA+     +LI   LRN  P
Sbjct: 56  EGSKVKFIATATIGFDHIDTEYCKQAGIEWANAPGCNSASVAQYIQSSLLIWKSLRNKKP 115

Query: 241 GYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP 420
                                 +  T+G +G G +G  + +  + F   +L +D     P
Sbjct: 116 ----------------------DELTIGIIGVGNVGSKVAKVAQDFGMRVLLNDL----P 149

Query: 421 ELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNA 588
             EKE    F   L+ +  +CD++  + PL +    KT  + +      +++  +++N +
Sbjct: 150 REEKEGNITF-TSLEKIAEECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTS 208

Query: 589 RGAIMDT 609
           RG +++T
Sbjct: 209 RGEVIET 215

---

>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)|
          Length = 304

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 35/101 (34%), Positives = 53/101 (52%)
 Frame = +1

Query: 307 EGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCD 486
           + KTV  +GAG IG  LL+ LKPFN   +  +      E   E  A   +  + +  + D
Sbjct: 125 DNKTVAILGAGGIGVRLLEMLKPFNVKTIAVNNSGRPVEGADETFAM--DKAEHVWAEAD 182

Query: 487 VVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
           V V+  PLT+ T  + N E + KMK   ++VN  RG +++T
Sbjct: 183 VFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINT 223

---

>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)|
          Length = 304

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 35/101 (34%), Positives = 53/101 (52%)
 Frame = +1

Query: 307 EGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCD 486
           + KTV  +GAG IG  LL+ LKPFN   +  +      E   E  A   +  + +  + D
Sbjct: 125 DNKTVAILGAGGIGVRLLEMLKPFNVKTIAVNNSGRPVEGADETFAM--DKAEHVWAEAD 182

Query: 487 VVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
           V V+  PLT+ T  + N E + KMK   ++VN  RG +++T
Sbjct: 183 VFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINT 223

---

>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/168 (23%), Positives = 78/168 (46%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ V   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRF-PDIERRVQAHDFTWQA 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   +  +D    N +L+      +++ + 
Sbjct: 138 EIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYP-NKDLDF---LTYKDSVK 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  +++  +F+K     +KKG I+VN ARGA+++T
Sbjct: 194 EAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINT 241

---

>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/168 (23%), Positives = 78/168 (46%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ V   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRF-PDIERRVQAHDFTWQA 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   +  +D    N +L+      +++ + 
Sbjct: 138 EIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYP-NKDLDF---LTYKDSVK 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  +++  +F+K     +KKG I+VN ARGA+++T
Sbjct: 194 EAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINT 241

---

>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/168 (23%), Positives = 78/168 (46%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ V   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRF-PDIERRVQAHDFTWQA 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   +  +D    N +L+      +++ + 
Sbjct: 138 EIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYP-NKDLDF---LTYKDSVK 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  +++  +F+K     +KKG I+VN ARGA+++T
Sbjct: 194 EAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINT 241

---

>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/168 (23%), Positives = 78/168 (46%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ V   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRF-PDIERRVQAHDFTWQA 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   +  +D    N +L+      +++ + 
Sbjct: 138 EIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYP-NKDLDF---LTYKDSVK 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  +++  +F+K     +KKG I+VN ARGA+++T
Sbjct: 194 EAIKDADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINT 241

---

>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 39/168 (23%), Positives = 78/168 (46%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ V   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRF-PDIERRVQAHDFTWQA 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   +  +D    N +L+      +++ + 
Sbjct: 138 EIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYP-NKDLDF---LTYKDSVK 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  +++  +F+K     +KKG I+VN ARGA+++T
Sbjct: 194 EAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINT 241

---

>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 380

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 4/175 (2%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           T  IG+DH+DL      G+  +   G N   V +  L  +L L              E +
Sbjct: 64  TCTIGTDHLDLDYFAEAGIHWSSAPGCNARGVVDYVLGSLLTL-------------AELD 110

Query: 274 VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 453
              +  R Y       G VGAG +G  L++ L      +L  D L+   E     G  + 
Sbjct: 111 GVALPERVY-------GVVGAGEVGGRLVRVLHGLGWKVLVCDPLRQAAE-----GGDY- 157

Query: 454 EDLDAMLPKCDVVVINTPL----TEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
             L+ +L +CDV+ ++TPL       T  +  + ++A+++ G  +VN +RG ++D
Sbjct: 158 VSLETILQQCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVD 212

---

>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
           (Fragment)
          Length = 274

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 4/105 (3%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKC 483
           L+ KTVG VGAG  G  + + L+ +   +L HD     P ++      F   LD ++  C
Sbjct: 2   LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHD-----PVIQDSDPRDF-ISLDELIACC 55

Query: 484 DVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           DV+ ++ P+T+    KT  +F++ ++  +K+G  ++N  RG ++D
Sbjct: 56  DVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVID 100

---

>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 39/168 (23%), Positives = 78/168 (46%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ V   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRF-PDIERRVQTHDFTWQA 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   +  +D    N +L+      +++ + 
Sbjct: 138 EIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYP-NKDLDF---LTYKDSVK 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  +++  +F+K     +KKG I+VN ARGA+++T
Sbjct: 194 EAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINT 241

---

>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 39/168 (23%), Positives = 78/168 (46%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ V   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLDLAKKHNIVISNVPSYSPETIAEYSVSIALQLVRRF-PDIERRVQTHDFTWQA 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   +  +D    N +L+      +++ + 
Sbjct: 138 EIMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYP-NKDLDF---LTYKDSVK 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  +++  +F+K     +KKG I+VN ARGA+++T
Sbjct: 194 EAIKDADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINT 241

---

>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           TA  G+DH+D       G+  +   G N ++V E     ++++      G+Q        
Sbjct: 64  TATAGTDHVDDTWLRQQGIGFSAAPGCNAIAVVEYVFSALMMMAER--DGFQ-------- 113

Query: 274 VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 453
                     L  KTVG +G G +G  L  RL+      L  D     P  ++     F 
Sbjct: 114 ----------LRDKTVGIIGVGNVGSRLNARLQALGVRTLLCD----PPRADRGDNEAF- 158

Query: 454 EDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
             L+ ++ + DV+  +TPL +    ++  M + E +A +  G I++N  RGA++D
Sbjct: 159 WPLEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVD 213

---

>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 375

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 4/175 (2%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           TA  G+DH+D       G+  +   G N ++V E     ++++      G+Q        
Sbjct: 64  TATAGTDHVDDTWLRQQGIGFSAAPGCNAIAVVEYVFSALMMMAER--DGFQ-------- 113

Query: 274 VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 453
                     L  KTVG +G G +G  L  RL+      L  D     P  ++     F 
Sbjct: 114 ----------LRDKTVGIIGVGNVGSRLNARLQALGVRTLLCD----PPRADRGDNEAF- 158

Query: 454 EDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
             L+ ++ + DV+  +TPL +    ++  M + E +A +  G I++N  RGA++D
Sbjct: 159 WPLEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVD 213

---

>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
           (Fragment)
          Length = 274

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 4/105 (3%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKC 483
           L+ KTVG VGAG  G  + + L+ +   +L HD     P ++      F   LD ++ +C
Sbjct: 2   LKDKTVGIVGAGNTGSAVAKCLQAYGVTVLLHD-----PVIQDSDPRDF-ISLDELIARC 55

Query: 484 DVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
           DV+ ++ P+ +    KT  +F++ ++  +K G  ++N  RG ++D
Sbjct: 56  DVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVID 100

---

>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 378

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)
 Frame = +1

Query: 94  TAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWN 273
           +A  G+DH+D       G+  +   G N ++V E     +L+L      G+Q        
Sbjct: 64  SATAGTDHVDDTWLNANGIAFSAAPGCNAIAVVEYVFSSLLMLAER--DGFQ-------- 113

Query: 274 VAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE 453
                     L  KTVG VG G +GR L  RLK +    L  D     P  ++     F 
Sbjct: 114 ----------LRDKTVGIVGVGNVGRRLDTRLKAWGVKTLLCD----PPRADRGDAGDF- 158

Query: 454 EDLDAMLPKCDVVVINTPL----TEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
             L+ ++   D++ ++TPL      +T  + +   +     G I++N  RG ++D
Sbjct: 159 LSLETLVRDADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVD 213

---

>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 331

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 47/182 (25%), Positives = 80/182 (43%), Gaps = 2/182 (1%)
 Frame = +1

Query: 70  AKNLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQ 249
           A  L++L T   G D  +       G+ +  V   +  ++ E  L   L L R+      
Sbjct: 67  ACKLKVLSTRTAGFDMYNATLLKKHGIRLTNVPSYSPNAIGEYALAAALQLTRHAREIET 126

Query: 250 QVVKGE--WNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPE 423
            V K +  W    ++    +L    VG +G GRIG+   +  K     ++  D    +  
Sbjct: 127 FVRKRDFRWQKPILSK---ELRCSRVGILGTGRIGQAAARLFKGVGAQVVGFDPYPNDAA 183

Query: 424 LEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIM 603
            E       +E    +L   DV+ ++ P T+ +  + N + IA+MK GV +VN ARGA++
Sbjct: 184 KEWLTYVSMDE----LLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVI 239

Query: 604 DT 609
           D+
Sbjct: 240 DS 241

---

>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 37/168 (22%), Positives = 77/168 (45%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ +   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKF-PTIEKRVQAHNFTWAS 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   ++ +D    N  L      +++E ++
Sbjct: 138 PIMSRPVKNMTVAIIGTGRIGAATGKIYAGFGARVVGYDAYP-NHSLSF---LEYKETVE 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  + +  +F+      +KKG ++VN ARGA+++T
Sbjct: 194 DAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINT 241

---

>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific|
           D-2-hydroxyacid dehydrogenase)
          Length = 330

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 37/168 (22%), Positives = 77/168 (45%)
 Frame = +1

Query: 106 GSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGI 285
           G D  DL       + ++ +   +  ++AE  +   L L+R F P  ++ V+        
Sbjct: 79  GFDMYDLELAKKHEIIISNIPSYSPETIAEYSVSIALQLVRKF-PTIEKRVQAHNFTWAS 137

Query: 286 AHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLD 465
              +  ++  TV  +G GRIG    +    F   ++ +D    N  L      +++E ++
Sbjct: 138 PIMSRPVKNMTVAIIGTGRIGAATGKIYAGFGARVVGYDAYP-NHSLSF---LEYKETVE 193

Query: 466 AMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDT 609
             +   D++ ++ P  + +  +F+      +KKG ++VN ARGA+++T
Sbjct: 194 DAIKDADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINT 241

---

>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)|
          Length = 325

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 1/100 (1%)
 Frame = +1

Query: 298 YDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQIN-PELEKEIGAKFEEDLDAML 474
           Y  E  T+G +GAG +G  + Q L+ +   L    R + + P ++   G    E+L A L
Sbjct: 145 YHREDFTIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAG---REELSAFL 201

Query: 475 PKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARG 594
            +C V++   P T +T G+ N++ + K+  G  ++N ARG
Sbjct: 202 SQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARG 241

---

>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 366

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 44/181 (24%), Positives = 76/181 (41%), Gaps = 5/181 (2%)
 Frame = +1

Query: 79  LELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILIL-LRNFLPGYQQV 255
           +E + +A  G DHID        +  A   G+N  +VAE  L  +  L  +N LP     
Sbjct: 60  VEFVGSATAGFDHIDSTWLKKQSIHWAYAPGANATAVAEYVLHCVAYLHKKNLLP----- 114

Query: 256 VKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKE 435
                            +  T   +G G +G ++  RL+     + ++D      +LEK+
Sbjct: 115 ----------------RKSATAAIIGVGHVGCVVSDRLRKIGFTVFHND--PPRAQLEKD 156

Query: 436 IGAKFEEDLDAMLPKCDVVVINTPLTE----KTRGMFNKEKIAKMKKGVIIVNNARGAIM 603
               F     A L   D+V ++TPL +     T  + +   +  +K G +++N  RGA++
Sbjct: 157 ----FISVPLASLANVDLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVI 212

Query: 604 D 606
           D
Sbjct: 213 D 213

---

>PDXB_PORGI (Q7MV70) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)|
          Length = 377

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 44/183 (24%), Positives = 71/183 (38%), Gaps = 5/183 (2%)
 Frame = +1

Query: 76  NLELLLTAGIGSDHIDLPXXXXXGLTVAEVTGSNTVSVAEDELMRILILLRNFLPGYQQV 255
           ++ L+ TA  G DHID       G+      G N  +VA+  +  +  L           
Sbjct: 66  DVRLITTATAGFDHIDREYCESHGILWRNSPGCNATAVAQYVMCCLCRLA---------- 115

Query: 256 VKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKE 435
                         + L+ K +G VG G +G  L +    +    L  D     P  E E
Sbjct: 116 ----------LREGFSLKEKVMGIVGVGHVGGELKRLASAYGMEFLLCDP----PRSEAE 161

Query: 436 IGAKFEEDLDAMLPKCDVVVINTPLT-EKTRGMFNKEKIAKMK----KGVIIVNNARGAI 600
               F   L  ++ +CD++  + PLT E     ++    A ++    K  I++N  RGA+
Sbjct: 162 QDNSFLP-LSRLVEQCDIISFHVPLTHEDPHATYHLIGEAFLRSCADKRPILINACRGAV 220

Query: 601 MDT 609
            DT
Sbjct: 221 ADT 223

---

>HEM1_METJA (Q60172) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 392

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
 Frame = +1

Query: 283 IAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCN--LLYHDRLQINPELEKEIGA---K 447
           +A + + LEGK V  +GAG +  L+++ LK  N    ++ +   +   +L KE+G    K
Sbjct: 149 LAEKIFGLEGKNVLLIGAGEMANLVIKALKEKNIKAIIVANRTYEKAEKLAKELGGMAIK 208

Query: 448 FEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVII 576
           F++ L+  L   D+V+     T     + NKE++    K +II
Sbjct: 209 FDK-LEEALRYADIVI---SATGAPHPILNKERLKNAGKTIII 247

---

>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)|
          Length = 379

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
 Frame = +1

Query: 310 GKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKF---EEDLDAMLPK 480
           GK    +G G IG+ +  +L+      +++ +   +  + +    KF   +E + A L +
Sbjct: 197 GKKCLILGLGSIGKQVAYKLQYGLGMEIHYCKRSEDCTMSQNESWKFHLLDETIYAKLYQ 256

Query: 481 CDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMD 606
              +V+  P T +T  + N++ +     G+I+VN  RG I+D
Sbjct: 257 FHAIVVTLPGTPQTEHLINRKFLEHCNPGLILVNLGRGKILD 298

---

>PUR6_CANGA (O74197) Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)|
           (AIR carboxylase) (AIRC)
          Length = 570

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 20/71 (28%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD-----RLQINPELEKEIGA-KFEEDLD 465
           ++ +TVG +G G++GR++++     N   L  D       QI    +   G+   +ED++
Sbjct: 1   MDSRTVGILGGGQLGRMIVEAANRLNIKTLILDAPNSPAKQITNASDHVDGSFANKEDIE 60

Query: 466 AMLPKCDVVVI 498
           A+  KCDV+ +
Sbjct: 61  ALAAKCDVMTV 71

---

>HEM1_PROMM (Q7V809) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 436

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 28/76 (36%), Positives = 38/76 (50%), Gaps = 9/76 (11%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCN---LLYHDRLQIN------PELEKEIGAKFEE 456
           LE + V  VGAGR+ RLLLQ L+   C+   LL   R +        PEL  E   +  +
Sbjct: 189 LESELVAVVGAGRMSRLLLQHLQAKGCSGVMLLNRTRQRAEDLSADFPELPVE--CRPLD 246

Query: 457 DLDAMLPKCDVVVINT 504
           DL+  L  C +V  +T
Sbjct: 247 DLNHCLSTCSLVFTST 262

---

>STRI_STRGR (P09400) Streptomycin biosynthesis protein strI (EC 1.-.-.-)|
          Length = 348

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 12/79 (15%)
 Frame = +1

Query: 319 VGTVGAGRIGRLLLQRL--KPFNCNLLYHDRLQINPE----LEKEIGA------KFEEDL 462
           VG VGAGR+GRL  + L   P   +L+ HD   ++P+    L +E+ A        E +L
Sbjct: 3   VGIVGAGRMGRLHARTLLELPDPPDLVVHD---VDPDGAHRLAQELAAGTKAQVTVEREL 59

Query: 463 DAMLPKCDVVVINTPLTEK 519
              + K D +V+ TP T++
Sbjct: 60  ADTVTKADAIVVATPATQR 78

---

>SAHH_METKA (P58855) Adenosylhomocysteinase (EC 3.3.1.1)|
           (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)
          Length = 424

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEE----DLDAM 471
           L GKTV  VG G  GR + +R +    N++    ++++P   K + A F+      +D  
Sbjct: 210 LAGKTVVVVGYGWCGRGIARRARGLGANVIV---VEVDPI--KAMEAIFDGFRVMPMDRA 264

Query: 472 LPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVN 582
             + D+ +  T   +  RG    E I KMK GVI+ N
Sbjct: 265 AEEGDIFITATGNRDVIRG----EHIEKMKDGVILAN 297

---

>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)|
           (TNNI3-interacting kinase) (Cardiac ankyrin repeat
           kinase)
          Length = 834

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 27/109 (24%), Positives = 44/109 (40%), Gaps = 9/109 (8%)
 Frame = -3

Query: 351 PANTTCPDSSDGLSLKIISPMGNACNIPFTFNDLLIARQEVPEQ-NQDAHELIFCHRDGV 175
           P N       DG  + + SP+G   ++     D+L+ R E+P + +    E+ F    G 
Sbjct: 411 PCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADVLLLRAELPSRFHLQLSEIEFHEIIGS 470

Query: 174 TSSDLCHSQACSSSSWQINMVRANPSCEK--------QLEVLCLLDPLC 52
            S    +   C +    I   RAN  C K        ++ +LC L+  C
Sbjct: 471 GSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPC 519

---

>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)|
           (TNNI3-interacting kinase) (Cardiac ankyrin repeat
           kinase)
          Length = 833

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 27/109 (24%), Positives = 44/109 (40%), Gaps = 9/109 (8%)
 Frame = -3

Query: 351 PANTTCPDSSDGLSLKIISPMGNACNIPFTFNDLLIARQEVPEQ-NQDAHELIFCHRDGV 175
           P N       DG  + + SP+G   ++     D+L+ R E+P + +    E+ F    G 
Sbjct: 410 PCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADVLLLRAELPSRFHLQLSEIEFHEIIGS 469

Query: 174 TSSDLCHSQACSSSSWQINMVRANPSCEK--------QLEVLCLLDPLC 52
            S    +   C +    I   RAN  C K        ++ +LC L+  C
Sbjct: 470 GSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPC 518

---

>LACC_STAAR (Q6GEN6) Tagatose-6-phosphate kinase (EC 2.7.1.144)|
           (Phosphotagatokinase)
          Length = 310

 Score = 33.5 bits (75), Expect = 0.50
 Identities = 31/138 (22%), Positives = 59/138 (42%), Gaps = 7/138 (5%)
 Frame = +1

Query: 217 ILLRNFLPG-YQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLL 393
           +L   F+ G   Q +  + + AGI H  Y+++G+T                    NC  +
Sbjct: 53  VLASGFIGGELGQFIAKKLDHAGIKHAFYNIKGET-------------------RNCIAI 93

Query: 394 YHDR-----LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAK- 555
            H+      L+  PE++ +  A F +  + +L K + V I+  L +     +  + I + 
Sbjct: 94  LHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERC 153

Query: 556 MKKGVIIVNNARGAIMDT 609
             KGV ++ +  GA + T
Sbjct: 154 QNKGVPVILDCSGATLQT 171

---

>SYH_THEAC (Q9HLX5) Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA|
           ligase) (HisRS)
          Length = 426

 Score = 33.1 bits (74), Expect = 0.66
 Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 7/106 (6%)
 Frame = +1

Query: 58  RIKKAKNLELLLTAGIGSDHIDLPXXXXXGLT----VAEVTGSNTVSVAEDELMRILIL- 222
           +I + + ++ L +AGIG D + +      G      +A +TG ++  +A    +  L+  
Sbjct: 192 KISREEFVDQLRSAGIGEDGVSMIADLCSGTRGIDEMARITGKSSEEIARMAAVEDLLAS 251

Query: 223 --LRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRL 354
             ++N    +  +V+G     GI   AYD  G+    +G GR   L
Sbjct: 252 YGVKNVRYDFS-IVRGLSYYTGIVFEAYDRSGQFRAILGGGRYDNL 296

---

>HEM1_ARCFU (O28304) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 437

 Score = 32.7 bits (73), Expect = 0.86
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 7/98 (7%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRL--KPFNCNLLYHDRLQINPELEKEIG---AKFEEDLDA 468
           L+GK    VGAG +G L+ + +  K     L+ +   +   EL K IG    KF++ +D 
Sbjct: 168 LKGKKALLVGAGEMGTLVAKAIAGKEVEAVLIANRTYEKAEELAKRIGGVAVKFDKLVD- 226

Query: 469 MLPKCDVVVINT--PLTEKTRGMFNKEKIAKMKKGVII 576
            L  CDVV+  T  P    TRG   +    + +K +II
Sbjct: 227 YLKVCDVVISATSAPHAVITRGDVERAMRERSQKLLII 264

---

>ARODE_CHLMU (P56961) Shikimate biosynthesis protein aroDE [Includes:|
           3-dehydroquinate dehydratase (EC 4.2.1.10)
           (3-dehydroquinase) (Type I DHQase); Shikimate
           dehydrogenase (EC 1.1.1.25)]
          Length = 478

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 20/70 (28%), Positives = 34/70 (48%)
 Frame = +1

Query: 214 LILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLL 393
           L++ +  + GY    +G ++V  +     DL  + V  +GAG   R +  RL    C LL
Sbjct: 300 LVIRQGEIIGYDTDGEGLFSV--LTQHNMDLSNQRVAILGAGGAARSIAARLSRTGCELL 357

Query: 394 YHDRLQINPE 423
             +R +I+ E
Sbjct: 358 IFNRTKIHAE 367

---

>HEM1_PROMP (Q7V1T7) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 433

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 11/98 (11%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEK-----------EIGAKF 450
           L+ + V  VGAGR+ RLL+  LK   CN L      +N  +E+           EI  K 
Sbjct: 189 LKSEKVLVVGAGRMSRLLITHLKSKGCNRL----TLLNRNIERAVNLAGDFPDLEINCKS 244

Query: 451 EEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKK 564
             +LD  +    +V  +T   +    +   EKI+   K
Sbjct: 245 LNELDKNISLSSLVFTSTASEKPFIDLARVEKISLNNK 282

---

>HEM1_METAC (Q8TT60) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 460

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 6/97 (6%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLY--HDRLQINPELEKEIG--AKFEEDLDAM 471
           L GK+V  +GAG IG L+ + L   +   +Y  +   +   E+  E+G  A   +D+   
Sbjct: 171 LTGKSVLVIGAGEIGVLVAKALAEKDIEAIYIANRTFKKAEEIAYELGGYAVRLDDIRGH 230

Query: 472 LPKCDVVVINT--PLTEKTRGMFNKEKIAKMKKGVII 576
           LP  DVV+  T  P    TR M  +    + +K ++I
Sbjct: 231 LPDADVVISGTGAPHYILTREMIEEALDGRERKLLLI 267

---

>ILVC2_SULSO (Q97YJ9) Putative ketol-acid reductoisomerase 2 (EC 1.1.1.86)|
           (Acetohydroxy-acid isomeroreductase 2)
           (Alpha-keto-beta-hydroxylacil reductoisomerase 2)
          Length = 333

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 25/88 (28%), Positives = 46/88 (52%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKC 483
           L+GKT+G +G G  GR+    ++    N++  +      EL K+ G +  E +D  + + 
Sbjct: 13  LKGKTIGVIGYGNQGRVQATIMRENGLNVIVGNVKDKYYELAKKEGFEVYE-IDEAVRRS 71

Query: 484 DVVVINTPLTEKTRGMFNKEKIAKMKKG 567
           DV ++  P  E  + ++ K KIA + +G
Sbjct: 72  DVALLLIP-DEVMKEVYEK-KIAPVLQG 97

---

>VPS41_CAEEL (Q19954) Vacuolar assembly protein VPS41 homolog|
          Length = 759

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
 Frame = -3

Query: 504 CVDHNDITLWKHSIQVLFKFRPNFFLKLWVDLKSVMVEQVAVEGLQALK*EPANTTCPDS 325
           C D ND  LW H + V+ +F P  F +L ++  + +   + ++ L      P ++  P+ 
Sbjct: 593 CKDQNDPDLWIHLLGVVAEF-PAHFSQLIIEASNCLDPLLIMDKL------PDDSDIPNL 645

Query: 324 SDGLSLKIISPMGNA----CNIPFTFNDLLIARQ 235
           S+ L   ++    +A    C    T NDL +  Q
Sbjct: 646 SEALDKLLVDYTNHAELQQCCYDSTLNDLNVLTQ 679

---

>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)|
           (TNNI3-interacting kinase) (Cardiac ankyrin repeat
           kinase)
          Length = 936

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
 Frame = -3

Query: 351 PANTTCPDSSDGLSLKIISPMGNACNIPFTFNDLLIARQEVPEQ-NQDAHELIFCHRDGV 175
           P N       DG  + + SP+G   ++     D+L+ R  +P   +    E+ F    G 
Sbjct: 513 PCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGS 572

Query: 174 TSSDLCHSQACSSSSWQINMVRANPSCEK--------QLEVLCLLDPLC 52
            S    +   C +    I   RAN  C K        ++ +LC L+  C
Sbjct: 573 GSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPC 621

---

>MET8_YEAST (P15807) Siroheme biosynthesis protein MET8 [Includes: Precorrin-2|
           dehydrogenase (EC 1.3.1.76); Sirohydrochlorin
           ferrochelatase (EC 4.99.1.4)]
          Length = 274

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 17/52 (32%), Positives = 26/52 (50%)
 Frame = +1

Query: 295 AYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKF 450
           A+ L+ K +  +G G +G   L +L P  C L       ++P+L K I  KF
Sbjct: 8   AHQLKDKKILLIGGGEVGLTRLYKLIPTGCKLTL-----VSPDLHKSIIPKF 54

---

>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)|
           (TNNI3-interacting kinase)
          Length = 617

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 9/109 (8%)
 Frame = -3

Query: 351 PANTTCPDSSDGLSLKIISPMGNACNIPFTFNDLLIARQEVPEQ-NQDAHELIFCHRDGV 175
           P N       DG  + + SP+G   ++     D+L+ R  +P   +    E+ F    G 
Sbjct: 411 PCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGS 470

Query: 174 TSSDLCHSQACSSSSWQINMVRANPSCEK--------QLEVLCLLDPLC 52
            S    +   C +    I   RAN  C K        ++ +LC L+  C
Sbjct: 471 GSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPC 519

---

>HEM1_OCEIH (Q8EPM7) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 457

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 8/97 (8%)
 Frame = +1

Query: 301 DLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELE--KEIGAKFEEDLDA-- 468
           DL+ K V  +GAG++G L  + ++      +      +N  LE   E+  KF  D+++  
Sbjct: 179 DLQEKHVAILGAGKMGELAAKNIQGSGATKI----TVVNRTLENANEMAEKFNADVESID 234

Query: 469 ----MLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKG 567
               +L + D+++ +T            EK+ K +KG
Sbjct: 235 QLPVILQQADILISSTGADSIVVTKEMMEKVQKQRKG 271

---

>RFC1_MOUSE (P35601) Activator 1 140 kDa subunit (Replication factor C large|
            subunit) (A1 140 kDa subunit) (RF-C 140 kDa subunit)
            (Activator 1 large subunit) (A1-P145)
            (Differentiation-specific element-binding protein)
            (ISRE-binding protein)
          Length = 1131

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
 Frame = +1

Query: 367  LKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTEKTR----GMF 534
            L P++  ++   RL   P L+ E   +F+ED      + D V  +  + +KTR       
Sbjct: 1056 LTPYSLQVVKTSRLSTGPALDSEYSEEFQEDDTQSEKEQDAVETDAMIKKKTRSSKPSKS 1115

Query: 535  NKEKIAKMKKG 567
             +EK +K  KG
Sbjct: 1116 EREKESKKGKG 1126

---

>DHLE_BACLI (Q53560) Leucine dehydrogenase (EC 1.4.1.9) (LeuDH)|
          Length = 364

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 4/83 (4%)
 Frame = +1

Query: 253 VVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEK 432
           V KG    A  A     LEGKTV   G G +   L + L      L+  D   IN E  +
Sbjct: 154 VYKGMKAAAKAAFGTDSLEGKTVAVQGVGNVAYNLCRHLHEEGAKLIVTD---INKEAVE 210

Query: 433 ----EIGAKFEEDLDAMLPKCDV 489
               E GA+  +  D    +CD+
Sbjct: 211 RAVAEFGARAVDPDDIYSQECDI 233

---

>HEM1_SYNPX (Q7U769) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 432

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 10/77 (12%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCN-LLYHDRLQINPELEKEIGAKFEE-------- 456
           LE + +  VGAGR+ RLLLQ L+    + ++  +R     EL   + A F +        
Sbjct: 189 LESEQIAVVGAGRMSRLLLQHLQAKGASGVVLLNRTVQRAEL---LAADFPDLPVQCRPL 245

Query: 457 -DLDAMLPKCDVVVINT 504
            DLD  L  C +V  +T
Sbjct: 246 TDLDQCLSTCSLVFTST 262

---

>HEM1_PROMA (Q7VCA1) Glutamyl-tRNA reductase (EC 1.2.1.70) (GluTR)|
          Length = 437

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 13/30 (43%), Positives = 20/30 (66%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLL 393
           L+ + V  +GAGR+ RLL+Q L+   C+ L
Sbjct: 189 LQSEKVAVIGAGRMSRLLIQHLQSKGCSKL 218

---

>TALA_SALTY (Q8ZN83) Transaldolase A (EC 2.2.1.2)|
          Length = 316

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +1

Query: 400 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE-KTRGMFNKEKIA--KMKKGV 570
           DRL I+P L KE+  K E  +  ++P   +    TP+TE + R   N++ +A  K+ +G+
Sbjct: 239 DRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGI 298

---

>TALA_SALTI (Q8Z4T0) Transaldolase A (EC 2.2.1.2)|
          Length = 316

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +1

Query: 400 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE-KTRGMFNKEKIA--KMKKGV 570
           DRL I+P L KE+  K E  +  ++P   +    TP+TE + R   N++ +A  K+ +G+
Sbjct: 239 DRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGI 298

---

>TAL2_SALCH (Q57LN7) Transaldolase 2 (EC 2.2.1.2)|
          Length = 316

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
 Frame = +1

Query: 400 DRLQINPELEKEIGAKFEEDLDAMLPKCDVVVINTPLTE-KTRGMFNKEKIA--KMKKGV 570
           DRL I+P L KE+  K E  +  ++P   +    TP+TE + R   N++ +A  K+ +G+
Sbjct: 239 DRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMTEAEFRWEHNQDAMAVEKLSEGI 298

---

>HYPF2_RALEU (O07451) Carbamoyltransferase hypF2 (EC 2.1.3.-) (Carbamoyl|
           phosphate-converting enzyme hypF2) ([NiFe]-hydrogenase
           maturation factor hypF2) (Hydrogenase maturation protein
           hypF2)
          Length = 806

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
 Frame = +1

Query: 169 GSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIA----HRAYDLEGKTVGTVGA 336
           G  T +     L+    L R  LPG  +  +  W +A  A     R  ++EG+     GA
Sbjct: 551 GGETAAGGRRRLLAPRSLARLPLPGGDRAAREPWRMAAAALHAMGRGEEIEGRFPRQPGA 610

Query: 337 GRIGRLLLQRL 369
             + R+L QRL
Sbjct: 611 PMVNRMLAQRL 621

---

>CH60_CHLMU (Q59322) 60 kDa chaperonin (Protein Cpn60) (groEL protein) (Heat|
           shock protein 60) (HSP60)
          Length = 543

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
 Frame = +1

Query: 187 VAEDELMRI----LILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRI-GR 351
           V ED L+ I    +  +++FLP  QQV +    +  IA    D+EG+ + T+   RI G 
Sbjct: 213 VLEDALVLIYDKKISGIKDFLPVLQQVAESGRPLLIIAE---DIEGEALATLVVNRIRGG 269

Query: 352 LLLQRLKPFNCNLLYHDRLQINPE----------LEKEIGAKFEEDLDAMLPKCDVVVIN 501
             +  +K       + DR +   E          + +E+G K E    AML K   V+++
Sbjct: 270 FRVCAVKAPG----FGDRRKAMLEDIAILTGGQLISEELGMKLENASLAMLGKAKKVIVS 325

Query: 502 TPLTEKTRGMFNKEKI 549
              T    GM  KE +
Sbjct: 326 KEDTTIVEGMGEKEAL 341

---

>PURK_STAAW (Q8NX94) Phosphoribosylaminoimidazole carboxylase ATPase subunit|
           (EC 4.1.1.21) (AIR carboxylase) (AIRC)
          Length = 374

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
 Frame = +1

Query: 310 GKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP---ELEKEIGAKFEED--LDAML 474
           G T+G +G G++G+++ Q  +     ++  D  +  P      + I AK++++  L+ + 
Sbjct: 9   GATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLG 68

Query: 475 PKCDVV 492
            KCDV+
Sbjct: 69  QKCDVI 74

---

>PURK_STAAS (Q6GAE8) Phosphoribosylaminoimidazole carboxylase ATPase subunit|
           (EC 4.1.1.21) (AIR carboxylase) (AIRC)
          Length = 374

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
 Frame = +1

Query: 310 GKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP---ELEKEIGAKFEED--LDAML 474
           G T+G +G G++G+++ Q  +     ++  D  +  P      + I AK++++  L+ + 
Sbjct: 9   GATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLG 68

Query: 475 PKCDVV 492
            KCDV+
Sbjct: 69  QKCDVI 74

---

>PURK_STAAN (Q7A695) Phosphoribosylaminoimidazole carboxylase ATPase subunit|
           (EC 4.1.1.21) (AIR carboxylase) (AIRC)
          Length = 374

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
 Frame = +1

Query: 310 GKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP---ELEKEIGAKFEED--LDAML 474
           G T+G +G G++G+++ Q  +     ++  D  +  P      + I AK++++  L+ + 
Sbjct: 9   GATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLG 68

Query: 475 PKCDVV 492
            KCDV+
Sbjct: 69  QKCDVI 74

---

>PURK_STAAM (Q99V32) Phosphoribosylaminoimidazole carboxylase ATPase subunit|
           (EC 4.1.1.21) (AIR carboxylase) (AIRC)
          Length = 374

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
 Frame = +1

Query: 310 GKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP---ELEKEIGAKFEED--LDAML 474
           G T+G +G G++G+++ Q  +     ++  D  +  P      + I AK++++  L+ + 
Sbjct: 9   GATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLG 68

Query: 475 PKCDVV 492
            KCDV+
Sbjct: 69  QKCDVI 74

---

>PURK_STAAC (Q5HH19) Phosphoribosylaminoimidazole carboxylase ATPase subunit|
           (EC 4.1.1.21) (AIR carboxylase) (AIRC)
          Length = 374

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
 Frame = +1

Query: 310 GKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP---ELEKEIGAKFEED--LDAML 474
           G T+G +G G++G+++ Q  +     ++  D  +  P      + I AK++++  L+ + 
Sbjct: 9   GATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLG 68

Query: 475 PKCDVV 492
            KCDV+
Sbjct: 69  QKCDVI 74

---

>PUR6_YEAST (P21264) Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)|
           (AIR carboxylase) (AIRC)
          Length = 571

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 7/72 (9%)
 Frame = +1

Query: 304 LEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD-----RLQINPELEKEIGAKFEE--DL 462
           ++ +TVG +G G++GR++++     N   +  D       QI+      +   F    D+
Sbjct: 1   MDSRTVGILGGGQLGRMIVEAANRLNIKTVILDAENSPAKQIS-NSNDHVNGSFSNPLDI 59

Query: 463 DAMLPKCDVVVI 498
           + +  KCDV+ I
Sbjct: 60  EKLAEKCDVLTI 71

---

>CH60_CHLTR (P0C0Z7) 60 kDa chaperonin (Protein Cpn60) (groEL protein) (57 kDa|
           chlamydial hypersensitivity antigen) (Heat shock protein
           60) (HSP60)
          Length = 543

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
 Frame = +1

Query: 187 VAEDELMRI----LILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRI-GR 351
           V ED L+ I    +  +++FLP  QQV +    +  IA    D+EG+ + T+   RI G 
Sbjct: 213 VLEDALVLIYDKKISGIKDFLPVLQQVAESGRPLLIIAE---DIEGEALATLVVNRIRGG 269

Query: 352 LLLQRLKPFNCNLLYHDRLQINPE----------LEKEIGAKFEEDLDAMLPKCDVVVIN 501
             +  +K       + DR +   E          + +E+G K E    AML K   V+++
Sbjct: 270 FRVCAVKAPG----FGDRRKAMLEDIAILTGGQLISEELGMKLENANLAMLGKAKKVIVS 325

Query: 502 TPLTEKTRGMFNKEKI 549
              T    GM  KE +
Sbjct: 326 KEDTTIVEGMGEKEAL 341

---

>SYM_SULSO (Q9UWW2) Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA|
           ligase) (MetRS)
          Length = 573

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
 Frame = +1

Query: 160 EVTGSNTVSVAEDELMRILILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAG 339
           E+   NT+ +  + +  I ILL   +P + Q +    N+  I +  +D+   T+      
Sbjct: 475 EIELKNTLYIGTNSVKTIAILLYPLMPSHAQKIYEMLNMGNIENEKWDV-ASTLSVNPGH 533

Query: 340 RIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFE---EDLDAMLP 477
           +IG++          N+L+    ++ PE E +I  K E   +D++ + P
Sbjct: 534 KIGKV----------NVLFK---KLEPEFESKIKDKLEKIRKDIEKIRP 569

---

>SYH_THEVO (Q97CE6) Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA|
           ligase) (HisRS)
          Length = 426

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
 Frame = +1

Query: 154 VAEVTGSNTVSVAEDELMRILILLRNFLPGYQQV------VKGEWNVAGIAHRAYDLEGK 315
           ++ + GS  VS A + L+R + +L+ +  G + V      V+G     G+   AYD  G+
Sbjct: 225 ISGLFGSGKVSKAAERLIRTIDILKEY--GVKSVKYDFSIVRGLSYYTGLVFEAYDKSGQ 282

Query: 316 TVGTVGAGRIGRL 354
               +G GR   L
Sbjct: 283 FRAILGGGRYDNL 295

---

>DHLE_BACST (P13154) Leucine dehydrogenase (EC 1.4.1.9) (LeuDH)|
          Length = 367

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 1/108 (0%)
 Frame = +1

Query: 253 VVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD-RLQINPELE 429
           V +G    A  A  +  LEGK V   G G +   L + L      L+  D   ++     
Sbjct: 154 VYRGMKAAAKEAFGSDSLEGKVVAVQGVGNVAYHLCRHLHEEGAKLIVTDINKEVVARAV 213

Query: 430 KEIGAKFEEDLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVI 573
           +E GAK  +  D    +CD+     P      G+ N + I ++K  VI
Sbjct: 214 EEFGAKAVDPNDIYGVECDIF---APCA--LGGIINDQTIPQLKAKVI 256

---

>PURK_STAAR (Q6GI19) Phosphoribosylaminoimidazole carboxylase ATPase subunit|
           (EC 4.1.1.21) (AIR carboxylase) (AIRC)
          Length = 374

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 17/66 (25%), Positives = 35/66 (53%), Gaps = 5/66 (7%)
 Frame = +1

Query: 310 GKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINP---ELEKEIGAKFEED--LDAML 474
           G T+G +G G++G+++ Q  +     +   D  +  P      + I AK++++  L+ + 
Sbjct: 9   GATIGIIGGGQLGKMMAQSAQKMGYKVAVLDPAEDCPCRYVAHEFIQAKYDDEKALNQLG 68

Query: 475 PKCDVV 492
            KCDV+
Sbjct: 69  QKCDVI 74

---

>PROC_AQUAE (O66553) Pyrroline-5-carboxylate reductase (EC 1.5.1.2) (P5CR) (P5C|
           reductase)
          Length = 265

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
 Frame = +1

Query: 319 VGTVGAGRIGRL--LLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEEDLDAMLPKCDVV 492
           VG VG G +G+   L    K    N++  D++Q    L  E+G  F  D+  +    DVV
Sbjct: 10  VGIVGFGNMGQAFALCFSKKLGKENIIVTDKVQEKRNLATEMGIAFASDVKFLADNSDVV 69

Query: 493 VINTPLTEKTRGMFNKEKIAKMK--KGVII 576
           ++        +   ++E + K+K  KG+I+
Sbjct: 70  LV------AVKPKDSQEVLQKLKDYKGIIL 93

---

>DHLE_BACSU (P54531) Leucine dehydrogenase (EC 1.4.1.9) (LeuDH)|
          Length = 364

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 1/80 (1%)
 Frame = +1

Query: 253 VVKGEWNVAGIAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHD-RLQINPELE 429
           V +G    A  A     LEGKT+   G G +   L + L     NL+  D   Q      
Sbjct: 154 VYRGMKAAAKAAFGTDSLEGKTIAVQGVGNVAYNLCRHLHEEGANLIVTDINKQSVQRAV 213

Query: 430 KEIGAKFEEDLDAMLPKCDV 489
           ++ GA+  +  D     CD+
Sbjct: 214 EDFGARAVDPDDIYSQDCDI 233

---

>CH60_CHLTA (Q3KMQ9) 60 kDa chaperonin (Protein Cpn60) (groEL protein) (57 kDa|
           chlamydial hypersensitivity antigen) (Heat shock protein
           60) (HSP60)
          Length = 543

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
 Frame = +1

Query: 187 VAEDELMRI----LILLRNFLPGYQQVVKGEWNVAGIAHRAYDLEGKTVGTVGAGRI-GR 351
           V ED L+ I    +  +++FLP  QQV +    +  IA    D+EG+ + T+   RI G 
Sbjct: 213 VLEDALVLIYDKKISGIKDFLPILQQVAESGRPLLIIAE---DIEGEALATLVVNRIRGG 269

Query: 352 LLLQRLKPFNCNLLYHDRLQINPE----------LEKEIGAKFEEDLDAMLPKCDVVVIN 501
             +  +K       + DR +   E          + +E+G K E    AML K   V+++
Sbjct: 270 FRVCAVKAPG----FGDRRKAMLEDIAILTGGQLISEELGMKLENANLAMLGKAKKVIVS 325

Query: 502 TPLTEKTRGMFNKEKI 549
              T    GM  KE +
Sbjct: 326 KEDTTIVEGMGEKEAL 341

---

>POLG_HCVJL (Q68798) Genome polyprotein [Contains: Core protein p21 (Capsid|
           protein C) (p21); Core protein p19; Envelope
           glycoprotein E1 (gp32) (gp35); Envelope glycoprotein E2
           (NS1) (gp68) (gp70); p7; Protease NS2-3 (EC 3.4.22.-)
           (p23); Serine protease/N
          Length = 3021

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 15/39 (38%), Positives = 20/39 (51%)
 Frame = +1

Query: 283 IAHRAYDLEGKTVGTVGAGRIGRLLLQRLKPFNCNLLYH 399
           + HRAY  +G   G++GA  I  L +  L P    LL H
Sbjct: 806 LPHRAYAYDGVQAGSIGAAVIAALTIFSLTPAYKTLLAH 844

---

>SAHH_SULTO (Q975T0) Adenosylhomocysteinase (EC 3.3.1.1)|
           (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)
          Length = 415

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 39/163 (23%), Positives = 65/163 (39%), Gaps = 6/163 (3%)
 Frame = +1

Query: 115 HIDLPXXXXXGLTVAEVTGSNTVSVAEDE--LMRILILLRNFLPGY---QQVVKGEWNVA 279
           H ++P     G T    TG   +   E++  L   +I + N    Y    ++  G+  + 
Sbjct: 133 HENMPQLKLFGGTEETTTGVIRLKAMEEQGVLRYPVIAVNNAFTKYLFDNRIGTGQSTID 192

Query: 280 GIAHRAYDL-EGKTVGTVGAGRIGRLLLQRLKPFNCNLLYHDRLQINPELEKEIGAKFEE 456
           GI      L  GK     G G +GR + QRL+     ++    ++++P L          
Sbjct: 193 GILRATNILIAGKVAVVAGYGWVGRGIAQRLRGMGARVIV---VEVSP-LRALEAVMDGF 248

Query: 457 DLDAMLPKCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNN 585
           D+  M    ++  I    T     +  KE I KMK G I+ N+
Sbjct: 249 DVMPMSKAAELGEIFITATGNI-NVIRKEHILKMKDGAILANS 290

---

>Y612_METJA (Q58029) Probable arogenate/prephenate dehydrogenase (EC 1.3.1.-)|
          Length = 446

 Score = 29.3 bits (64), Expect = 9.5
 Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
 Frame = +1

Query: 331 GAGRIGRLLLQRLKPFNCNLLYHDR-LQINPELEKEIGAKFEEDLDAMLPKCDVVVINTP 507
           G   +G+   + LK    N++   R ++    +EKE+G +F  +      K D+V++  P
Sbjct: 13  GTDGLGKWFARYLKNKGFNVIVTGRDIEKGKNVEKELGVEFTNNNIEAAKKGDIVIVAVP 72

Query: 508 LTEKTRGMFNKEKIAKMKKGVIIVN 582
           +    R +  KE    +++G ++++
Sbjct: 73  INVTERVI--KEVAPHVREGCLLMD 95


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,062,560
Number of Sequences: 219361
Number of extensions: 1762377
Number of successful extensions: 5972
Number of sequences better than 10.0: 162
Number of HSP's better than 10.0 without gapping: 5636
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5823
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5481822624
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

---