>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC|
           2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein
           slipper)
          Length = 1161

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 13/27 (48%), Positives = 16/27 (59%)
 Frame = -3

Query: 610 IPSETDPYWTSLILSCWETDPQSRPSF 530
           IP      W +L+ SCW+TDP  RP F
Sbjct: 366 IPKTCPETWGALMKSCWQTDPHKRPGF 392

>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)|
            (Tyrosine-protein kinase 1)
          Length = 1584

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 11/27 (40%), Positives = 17/27 (62%)
 Frame = -3

Query: 610  IPSETDPYWTSLILSCWETDPQSRPSF 530
            IP  T   W  ++  CW+++P SRP+F
Sbjct: 1526 IPLTTSSKWKEILTQCWDSNPDSRPTF 1552

>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)|
          Length = 410

 Score = 33.1 bits (74), Expect = 0.66
 Identities = 13/27 (48%), Positives = 14/27 (51%)
 Frame = -3

Query: 610 IPSETDPYWTSLILSCWETDPQSRPSF 530
           IP   DP    L+  CWE DP  RP F
Sbjct: 331 IPEYCDPELKLLLTQCWEADPNDRPPF 357

>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)|
          Length = 757

 Score = 32.7 bits (73), Expect = 0.87
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = -3

Query: 613 EIPSETDPYWTSLILSCWETDPQSRPSF 530
           E P E   +  S++LSCW  DP  RP+F
Sbjct: 706 EKPDECPIHTYSIMLSCWHIDPNKRPTF 733

>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related|
           intestinal kinase)
          Length = 451

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 13/26 (50%), Positives = 15/26 (57%)
 Frame = -3

Query: 607 PSETDPYWTSLILSCWETDPQSRPSF 530
           P E  P    L+LSCW  DP+ RP F
Sbjct: 409 PLECPPNIHKLMLSCWSRDPKQRPCF 434

>THYG_BOVIN (P01267) Thyroglobulin precursor|
          Length = 2769

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
 Frame = -2

Query: 566  LLGN*PTKPSII---PRTSGEAPGAAKEVRCPESSAAKCISCCEEQHYRGMKIPTTC*GG 396
            L+G     P+ +    R   +A   AKEV CP SS  + +SC  ++  R +    T    
Sbjct: 2413 LMGGSALSPAAVIRPERARQQAAALAKEVGCPSSSVQEMVSCLRQEPARILNDAQT---- 2468

Query: 395  VSVRVRGEHHQ*WSDASTQEKIRTSGVIVFAEQPMLKI 282
              + V G  H  W      + +R +   V    P +K+
Sbjct: 2469 KLLAVSGPFHY-WGPVVDGQYLRETPARVLQRAPRVKV 2505

>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC|
            2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor
            flk-1) (Fetal liver kinase 1) (Kinase NYK)
          Length = 1367

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 18/59 (30%), Positives = 23/59 (38%)
 Frame = -3

Query: 607  PSETDPYWTSLILSCWETDPQSRPSFXXXXXXXXXXXXKYAVQNQVQRNASAAAKNSII 431
            P  T P     +L CW  DP  RPSF               + N +Q NA    K+ I+
Sbjct: 1126 PDYTTPEMYQTMLDCWHEDPNQRPSFSELVEH---------LGNLLQANAQQDGKDYIV 1175

>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)|
          Length = 821

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 12/28 (42%), Positives = 16/28 (57%)
 Frame = -3

Query: 613 EIPSETDPYWTSLILSCWETDPQSRPSF 530
           EIP   +P   ++I  CW  +P  RPSF
Sbjct: 771 EIPRNLNPQVAAIIEGCWTNEPWKRPSF 798

>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)|
          Length = 2554

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 12/17 (70%), Positives = 13/17 (76%)
 Frame = -3

Query: 580  SLILSCWETDPQSRPSF 530
            SL+L CW TDP  RPSF
Sbjct: 2458 SLLLLCWRTDPWERPSF 2474

>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC|
           2.7.11.25) (Mixed lineage kinase 1)
          Length = 1104

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 13/27 (48%), Positives = 15/27 (55%)
 Frame = -3

Query: 610 IPSETDPYWTSLILSCWETDPQSRPSF 530
           IPS     +  L+  CW  DP SRPSF
Sbjct: 370 IPSTCPEPFAKLMEDCWNPDPHSRPSF 396

>VGFR2_RAT (O08775) Vascular endothelial growth factor receptor 2 precursor (EC|
            2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor
            flk-1) (Fetal liver kinase 1)
          Length = 1343

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 17/59 (28%), Positives = 23/59 (38%)
 Frame = -3

Query: 607  PSETDPYWTSLILSCWETDPQSRPSFXXXXXXXXXXXXKYAVQNQVQRNASAAAKNSII 431
            P  T P     +L CW  DP  RP+F               + N +Q NA    K+ I+
Sbjct: 1124 PDYTTPEMYQTMLDCWHEDPNQRPAFSELVEH---------LGNLLQANAQQDGKDYIV 1173

>PDE6_CAEEL (Q9N2V9) Probable 3',5'-cyclic phosphodiesterase pde-6 (EC|
           3.1.4.17)
          Length = 760

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 14/41 (34%), Positives = 21/41 (51%)
 Frame = -1

Query: 180 WRFWVLHSVAMRD*HAIGLIWLAFVTRRGWCFCVDCSDDKL 58
           W+F +LH   + D HA+  + +    R   C  + CSDD L
Sbjct: 444 WKFDILHLEKVSDHHALSQVGMKVFERWKVCDVLGCSDDLL 484

>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC|
           2.7.11.25) (MLK-like mitogen-activated protein triple
           kinase) (Leucine zipper-and sterile alpha
           motif-containing kinase) (Sterile alpha motif- and
           leucine zipper-containing kinase
          Length = 800

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 12/27 (44%), Positives = 15/27 (55%)
 Frame = -3

Query: 610 IPSETDPYWTSLILSCWETDPQSRPSF 530
           IPS     +  L+  CWE D + RPSF
Sbjct: 227 IPSSCPRSFAELLHQCWEADAKKRPSF 253

>GUC2C_RAT (P23897) Heat-stable enterotoxin receptor precursor (GC-C)|
           (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA
           receptor)
          Length = 1072

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 10/16 (62%), Positives = 12/16 (75%)
 Frame = -3

Query: 577 LILSCWETDPQSRPSF 530
           L+ SCWE DP+ RP F
Sbjct: 722 LVKSCWEEDPEKRPDF 737

>MYCL2_HUMAN (P12525) L-myc-2 protein|
          Length = 357

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 9/71 (12%)
 Frame = +2

Query: 230 EEVQAYPPTNSEDASSAQSSALAV-PQKQSHQRYESFLGLTRR--------SITDDVPPS 382
           EE+ + PP  SE A S Q   +    +  + ++Y S+L   RR        ++ D+V P+
Sbjct: 245 EEIVSLPPVESEAAQSCQPKPIHYDTENWTKKKYHSYLERKRRNDQRSRFLALRDEV-PA 303

Query: 383 LAH*PRLSKLL 415
           LA   R+SK++
Sbjct: 304 LASCSRVSKVM 314

>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine|
           leukemia viral oncogene homolog 2) (Tyrosine kinase ARG)
          Length = 1182

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 15/61 (24%), Positives = 23/61 (37%)
 Frame = -3

Query: 613 EIPSETDPYWTSLILSCWETDPQSRPSFXXXXXXXXXXXXKYAVQNQVQRNASAAAKNSI 434
           E P    P    L+ +CW+  P  RPSF              ++  +V      AA +S 
Sbjct: 505 EQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSS 564

Query: 433 I 431
           +
Sbjct: 565 V 565

>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC|
           2.7.11.25) (Mixed lineage kinase 4)
          Length = 1036

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 12/27 (44%), Positives = 15/27 (55%)
 Frame = -3

Query: 610 IPSETDPYWTSLILSCWETDPQSRPSF 530
           IPS     +  L+  CW+ DP  RPSF
Sbjct: 365 IPSTCPEPFAKLMKECWQQDPHIRPSF 391

>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC|
            2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1)
            (Quek 1) (Quek1)
          Length = 1348

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 11/26 (42%), Positives = 14/26 (53%)
 Frame = -3

Query: 607  PSETDPYWTSLILSCWETDPQSRPSF 530
            P  T P     +L CW  DP+ RP+F
Sbjct: 1121 PDYTTPEMYQTMLDCWHGDPKQRPTF 1146

>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC|
           2.7.11.25) (MLK-like mitogen-activated protein triple
           kinase) (Leucine zipper-and sterile alpha motif kinase
           ZAK) (Sterile alpha motif- and leucine zipper-containing
           kinase AZK) (
          Length = 802

 Score = 30.0 bits (66), Expect = 5.6
 Identities = 12/27 (44%), Positives = 15/27 (55%)
 Frame = -3

Query: 610 IPSETDPYWTSLILSCWETDPQSRPSF 530
           IPS     +  L+  CWE D + RPSF
Sbjct: 227 IPSSCPRSFAELLHQCWEADAKKRPSF 253

>THYG_RAT (P06882) Thyroglobulin precursor|
          Length = 2768

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
 Frame = -2

Query: 566  LLGN*PTKPSII---PRTSGEAPGAAKEVRCPESSAAKCISCCEEQ 438
            L+G     P+ I    R   +A   AKEV CP SS  + +SC  ++
Sbjct: 2413 LMGGSALSPAAIISPDRAQQQAAALAKEVGCPNSSVQEVVSCFRQK 2458

>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor|
           kinase) (Tyrosine-protein kinase BRK)
          Length = 451

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 12/26 (46%), Positives = 15/26 (57%)
 Frame = -3

Query: 607 PSETDPYWTSLILSCWETDPQSRPSF 530
           P E  P    L+L+CW  DP+ RP F
Sbjct: 409 PLECPPSVHKLMLTCWCRDPEQRPCF 434

>HAT2_USTMA (Q4P553) Histone acetyltransferase type B subunit 2 (EC 2.3.1.48)|
          Length = 485

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 12/25 (48%), Positives = 17/25 (68%)
 Frame = +3

Query: 384 SHTDPALASCWNLHSSIMLFFAAAD 458
           SHTD  L+ CW+ H + +L  A+AD
Sbjct: 378 SHTDEILSVCWSPHHATVLASASAD 402

>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)|
          Length = 517

 Score = 29.6 bits (65), Expect = 7.3
 Identities = 10/26 (38%), Positives = 14/26 (53%)
 Frame = -3

Query: 607 PSETDPYWTSLILSCWETDPQSRPSF 530
           P   +P    ++L CW  DP  RP+F
Sbjct: 468 PPNCEPRLYEIMLECWHKDPMRRPTF 493

>KLF16_MOUSE (P58334) Krueppel-like factor 16 (Transcription factor BTEB4)|
           (Basic transcription element-binding protein 4)
           (BTE-binding protein 4) (Dopamine receptor-regulating
           factor)
          Length = 251

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 13/21 (61%), Positives = 14/21 (66%)
 Frame = -2

Query: 524 TSGEAPGAAKEVRCPESSAAK 462
           +SG APGAAK  RCP    AK
Sbjct: 115 SSGRAPGAAKSHRCPFHGCAK 135

>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)|
          Length = 505

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 10/26 (38%), Positives = 15/26 (57%)
 Frame = -3

Query: 607 PSETDPYWTSLILSCWETDPQSRPSF 530
           P+     +  ++L CW  DP SRP+F
Sbjct: 457 PANCPKQFHDIMLDCWREDPASRPTF 482

>THYG_MOUSE (O08710) Thyroglobulin precursor|
          Length = 2766

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
 Frame = -2

Query: 566  LLGN*PTKPSII---PRTSGEAPGAAKEVRCPESSAAKCISCCEEQ 438
            L+G     P+ I    R   +A   AKEV CP SS  + +SC  ++
Sbjct: 2411 LMGGSALSPAAIISPERAQQQAAALAKEVGCPTSSIQEVVSCLRQK 2456

>DRP2_HUMAN (Q13474) Dystrophin-related protein 2|
          Length = 954

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
 Frame = +2

Query: 215 QKLRLEEVQAYPPTNSEDASSAQSSALAVPQKQ--SHQR 325
           Q  RL E+   PPT S+ + SA SS  + PQ+   SH R
Sbjct: 863 QLQRLRELLLQPPTESDGSGSAGSSLASSPQQSEGSHPR 901

>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)|
           (p59-Fyn)
          Length = 536

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 9/16 (56%), Positives = 14/16 (87%)
 Frame = -3

Query: 577 LILSCWETDPQSRPSF 530
           L+L+CW+ DP+ RP+F
Sbjct: 497 LMLNCWKKDPEERPTF 512


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,104,247
Number of Sequences: 219361
Number of extensions: 1945859
Number of successful extensions: 6042
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 5795
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6042
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5538924943
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)