ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | bags10p18 |
|---|---|
| Clone Library Name | barley_pub |
>CP51_WHEAT (P93596) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) (Fragment) Length = 453 Score = 403 bits (1035), Expect = e-112 Identities = 201/203 (99%), Positives = 203/203 (100%) Frame = +2 Query: 2 NKLRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSA 181 NKLRSYVD+MVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSA Sbjct: 106 NKLRSYVDQMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSA 165 Query: 182 LFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFI 361 LFHDLDNGM+PISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFI Sbjct: 166 LFHDLDNGMLPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFI 225 Query: 362 DSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMK 541 DSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMK Sbjct: 226 DSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMK 285 Query: 542 RHGDKIDHDILAEMDVLYRCIKE 610 RHGDKIDHDILAEMDVLYRCIKE Sbjct: 286 RHGDKIDHDILAEMDVLYRCIKE 308
>CP51_SORBI (P93846) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Obtusifoliol 14-alpha demethylase) Length = 492 Score = 387 bits (993), Expect = e-107 Identities = 190/203 (93%), Positives = 199/203 (98%) Frame = +2 Query: 2 NKLRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSA 181 NKLRSYVD+MVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSA Sbjct: 145 NKLRSYVDQMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSA 204 Query: 182 LFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFI 361 LFHDLDNG+ PISV+FPYLPIPAH+RRD+AR RLAEIFATIIKSRKASGQSEEDMLQCFI Sbjct: 205 LFHDLDNGIQPISVLFPYLPIPAHKRRDKARARLAEIFATIIKSRKASGQSEEDMLQCFI 264 Query: 362 DSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMK 541 DSKYKNGR TTE EVTGLLIAALFAGQHTSSITSTWTGAY+L+F+QYFAEAVEEQK+VMK Sbjct: 265 DSKYKNGRPTTEGEVTGLLIAALFAGQHTSSITSTWTGAYMLRFKQYFAEAVEEQKDVMK 324 Query: 542 RHGDKIDHDILAEMDVLYRCIKE 610 RHGDKIDHDILAEMDVLYRCIKE Sbjct: 325 RHGDKIDHDILAEMDVLYRCIKE 347
>CP51A_BOVIN (Q4PJW3) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 502 Score = 162 bits (411), Expect = 5e-40 Identities = 86/201 (42%), Positives = 124/201 (61%), Gaps = 1/201 (0%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFH 190 R +V + E +EYF WGESG +L L LIILTAS CL G+E+R +L + V+ L+ Sbjct: 168 RQHVSIIEKETKEYFKSWGESGEKNLFEALSELIILTASHCLHGKEIRSQLNEKVAQLYA 227 Query: 191 DLDNGMMPISVIFP-YLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDS 367 DLD G + + P +LP+P+ RRRD+A + IF I+ R+ SG+ +D+LQ ++S Sbjct: 228 DLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRESGEKIDDILQTLLES 287 Query: 368 KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRH 547 YK+GR T+ EV G+LI L AGQHTSS TS W G +L + + + EQK V + Sbjct: 288 TYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQEKCFLEQKTVCGEN 347 Query: 548 GDKIDHDILAEMDVLYRCIKE 610 + +D L ++++L RCIKE Sbjct: 348 LPPLTYDQLKDLNLLDRCIKE 368
>CP51A_RAT (Q64654) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 160 bits (405), Expect = 3e-39 Identities = 85/201 (42%), Positives = 123/201 (61%), Gaps = 1/201 (0%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFH 190 + YV + EA+EYF WGESG ++ L LIILTAS CL G+E+R +L + V+ L+ Sbjct: 169 KQYVSIIEKEAKEYFKSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYA 228 Query: 191 DLDNGMMPISVIFP-YLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDS 367 DLD G + + P +LP+P+ RRRD+A + IF I+ R+ S + ED+LQ +DS Sbjct: 229 DLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDS 288 Query: 368 KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRH 547 YK+GR T+ E+ G+LI L AGQHTSS TS W G +L + + + EQK V Sbjct: 289 TYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGED 348 Query: 548 GDKIDHDILAEMDVLYRCIKE 610 + ++ L ++++L RCIKE Sbjct: 349 LPPLTYEQLKDLNLLDRCIKE 369
>CP51A_PIG (O46420) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) Length = 503 Score = 160 bits (404), Expect = 4e-39 Identities = 86/201 (42%), Positives = 122/201 (60%), Gaps = 1/201 (0%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFH 190 R +V + E +EYF WGESG +L L LIILTAS CL G+E+R +L + V+ L+ Sbjct: 169 RQHVSIIEKETKEYFQSWGESGERNLFEALSELIILTASHCLHGKEIRSQLNEKVAQLYA 228 Query: 191 DLDNGMMPISVIFP-YLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDS 367 DLD G + + P +LP+P+ RRRD+A + IF I+ R+ S + +D+LQ +DS Sbjct: 229 DLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRQSEEKIDDILQTLLDS 288 Query: 368 KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRH 547 YK+GR T+ EV G+LI L AGQHTSS TS W G +L + + + EQK V Sbjct: 289 TYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQEKCYLEQKTVCGED 348 Query: 548 GDKIDHDILAEMDVLYRCIKE 610 + +D L ++++L RCIKE Sbjct: 349 LPPLTYDQLKDLNLLDRCIKE 369
>CP51A_PONPY (Q5RE72) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 159 bits (401), Expect = 8e-39 Identities = 84/201 (41%), Positives = 124/201 (61%), Gaps = 1/201 (0%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFH 190 + +V + E +EYF WGESG ++ L LIILTAS CL G+EVR +L + V+ L+ Sbjct: 169 KQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEVRSQLNEKVAQLYA 228 Query: 191 DLDNGMMPISVIFP-YLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDS 367 DLD G + + P +LP+P+ RRRD+A + +IF I+ R+ S + +D+LQ +D+ Sbjct: 229 DLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDA 288 Query: 368 KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRH 547 YK+GR T+ EV G+LI L AGQHTSS TS W G +L + + + EQK V + Sbjct: 289 TYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQEKCYLEQKTVCGEN 348 Query: 548 GDKIDHDILAEMDVLYRCIKE 610 + +D L ++++L RCIKE Sbjct: 349 LPPLTYDQLKDLNLLDRCIKE 369
>CP51A_HUMAN (Q16850) Cytochrome P450 51A1 (EC 1.14.13.70) (CYPLI) (P450LI)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (LDM) (P450-14DM) (P45014DM) Length = 503 Score = 158 bits (400), Expect = 1e-38 Identities = 83/201 (41%), Positives = 124/201 (61%), Gaps = 1/201 (0%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFH 190 + +V + E +EYF WGESG ++ L LIILTAS CL G+E+R +L + V+ L+ Sbjct: 169 KQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYA 228 Query: 191 DLDNGMMPISVIFP-YLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDS 367 DLD G + + P +LP+P+ RRRD+A + +IF I+ R+ S + +D+LQ +D+ Sbjct: 229 DLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDA 288 Query: 368 KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRH 547 YK+GR T+ EV G+LI L AGQHTSS TS W G +L + + + EQK V + Sbjct: 289 TYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGEN 348 Query: 548 GDKIDHDILAEMDVLYRCIKE 610 + +D L ++++L RCIKE Sbjct: 349 LPPLTYDQLKDLNLLDRCIKE 369
>CP51_CUNEL (Q9UVC3) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 512 Score = 142 bits (359), Expect = 6e-34 Identities = 77/202 (38%), Positives = 120/202 (59%), Gaps = 2/202 (0%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGE-SGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 R +V +V E EE+F K+ + +G ++ LII TASRCL+G+E+R L +V+ L+ Sbjct: 154 RQHVPMIVQETEEFFKKFNKPTGFIEAYETFGSLIIYTASRCLMGKEIRASLDGNVAKLY 213 Query: 188 HDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRK-ASGQSEEDMLQCFID 364 +DLD G PI+ IFP LP+P++RRRD A ++A+++++II+ RK + D+LQ +D Sbjct: 214 YDLDQGFKPINFIFPNLPLPSYRRRDVACKKMADLYSSIIQRRKDEKDNNNADLLQALMD 273 Query: 365 SKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKR 544 + YK+G + + G++IA LF GQHTS+ TS WT L EEQ E + Sbjct: 274 ATYKDGTHIPDHHIAGMMIAVLFGGQHTSATTSAWTILELANRPDIIKALREEQIEKLGS 333 Query: 545 HGDKIDHDILAEMDVLYRCIKE 610 + D L ++ +L I+E Sbjct: 334 LKADLTFDNLKDLPLLEAAIRE 355
>CP51_USTMA (P49602) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 561 Score = 133 bits (335), Expect = 4e-31 Identities = 75/191 (39%), Positives = 110/191 (57%), Gaps = 16/191 (8%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFS--------KWGESGTVDLKYELEHLIILTASRCLLGREVREKLF 166 R YV ++V E EY K ++ TVD+ + LIILTASR L G+EVR+ L Sbjct: 168 RVYVPQIVDEVREYIKSDARFSALKTRKTITVDIFQAMSELIILTASRTLQGKEVRQGLD 227 Query: 167 DDVSALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQS---- 334 + L+HDLD+G PI+ + P LP+P++ +RD+A+ ++++ + I+ R+A+G S Sbjct: 228 KSFAQLYHDLDSGFTPINFVIPNLPLPSNFKRDRAQKKMSQFYQDIVAKRRAAGASTSAD 287 Query: 335 ----EEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQY 502 E DM+ I+ KYKNGR + E+ ++IA L AGQHTSS TS+W L + Sbjct: 288 DASGENDMIAALIEQKYKNGRALSGVEIAHMMIALLMAGQHTSSATSSWAFLRLASRPEI 347 Query: 503 FAEAVEEQKEV 535 E EEQ V Sbjct: 348 IEELYEEQLNV 358
>CP51_YEAST (P10614) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 530 Score = 127 bits (319), Expect = 3e-29 Identities = 73/209 (34%), Positives = 116/209 (55%), Gaps = 9/209 (4%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGE-------SGTVDLKYELEHLIILTASRCLLGREVREKLFD 169 +SYV + E +YF +GT+D+ + I TASR LLG+E+R KL Sbjct: 164 KSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDT 223 Query: 170 DVSALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQ-SEEDM 346 D + L+ DLD G PI+ +FP LP+ +R+RD A+ ++ + ++IK R+ + + D+ Sbjct: 224 DFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDL 283 Query: 347 LQCFI-DSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEE 523 + + +S YK+G + T+ E+ LLI L GQHTS+ TS W +L + E EE Sbjct: 284 IDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEE 343 Query: 524 QKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 Q V+ ++ +D+L EM +L + IKE Sbjct: 344 QMRVLDGGKKELTYDLLQEMPLLNQTIKE 372
>CP51_SCHPO (Q09736) Probable cytochrome P450 51 (EC 1.14.13.70) (CYPLI)| (P450-LIA1) (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 495 Score = 123 bits (308), Expect = 5e-28 Identities = 74/209 (35%), Positives = 116/209 (55%), Gaps = 6/209 (2%) Frame = +2 Query: 2 NKLRSYVDRMVAEAEEYFSKW-----GESGTVDLKYELEHLIILTASRCLLGREVREKLF 166 ++ RSYV ++ E + + S G+ G DL + + I TASR L G EVR+ Sbjct: 138 SQFRSYVPLILNEMDAFLSTSPDFGPGKEGVADLLKTMPVMTIYTASRTLQGAEVRKGFD 197 Query: 167 DDVSALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSE-ED 343 + L+HDLD G P++ +FP+LP+P +RRRD+A + + + IIK R++S ++ D Sbjct: 198 AGFADLYHDLDQGFSPVNFVFPWLPLPRNRRRDRAHKIMQKTYLKIIKDRRSSTENPGTD 257 Query: 344 MLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEE 523 M+ + KY++GR E E+ G++IA L AGQHTS+ T W A L + EE Sbjct: 258 MIWTLMSCKYRDGRPLKEHEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEE 317 Query: 524 QKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 QK V+ + + + D +M +L I+E Sbjct: 318 QKRVVGENLE-LKFDQYKDMPLLNYVIQE 345
>CP51_CANGA (P50859) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha-demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 533 Score = 122 bits (307), Expect = 6e-28 Identities = 71/207 (34%), Positives = 111/207 (53%), Gaps = 9/207 (4%) Frame = +2 Query: 17 YVDRMVAEAEEYFSKW-------GESGTVDLKYELEHLIILTASRCLLGREVREKLFDDV 175 YV + E +YF SG VD+ + I TASR LLG+E+R+KL D Sbjct: 167 YVPLIAEEIYKYFRNSKNFKINENNSGIVDVMVSQPEMTIFTASRSLLGKEMRDKLDTDF 226 Query: 176 SALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASG--QSEEDML 349 + L+ DLD G PI+ +FP LP+ +R+RD A+ ++ + ++IK R+ Q+ + + Sbjct: 227 AYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQQAISGTYMSLIKERREKNDIQNRDLID 286 Query: 350 QCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQK 529 + +S YK+G + T+ E+ LLI L GQHTS+ TS W +L + E +EQ Sbjct: 287 ELMKNSTYKDGTKMTDQEIANLLIGVLMGGQHTSAATSAWCLLHLAERPDVQEELYQEQM 346 Query: 530 EVMKRHGDKIDHDILAEMDVLYRCIKE 610 V+ ++ +D L M +L + IKE Sbjct: 347 RVLNNDTKELTYDDLQNMPLLNQMIKE 373
>CP51_MYCTU (P0A512) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 119 bits (297), Expect = 9e-27 Identities = 70/205 (34%), Positives = 115/205 (56%), Gaps = 4/205 (1%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 + V RM+A+ WGE+G +DL L I T+S CL+G++ R++L + L+ Sbjct: 117 IEDQVRRMIAD-------WGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLY 169 Query: 188 HDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKA---SGQSEEDMLQCF 358 H+L+ G P++ + PYLPI + RRRD+AR L + A I+ R A + +S+ DML Sbjct: 170 HELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIMNGRIANPPTDKSDRDMLDVL 229 Query: 359 IDSKYKNGR-QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEV 535 I K + G + + E+TG+ I+ +FAG HTSS T++WT L++ + +A ++E E Sbjct: 230 IAVKAETGTPRFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDE- 288 Query: 536 MKRHGDKIDHDILAEMDVLYRCIKE 610 + G + L ++ L +KE Sbjct: 289 LYGDGRSVSFHALRQIPQLENVLKE 313
>CP51_MYCBO (P0A513) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 451 Score = 119 bits (297), Expect = 9e-27 Identities = 70/205 (34%), Positives = 115/205 (56%), Gaps = 4/205 (1%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 + V RM+A+ WGE+G +DL L I T+S CL+G++ R++L + L+ Sbjct: 117 IEDQVRRMIAD-------WGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLY 169 Query: 188 HDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKA---SGQSEEDMLQCF 358 H+L+ G P++ + PYLPI + RRRD+AR L + A I+ R A + +S+ DML Sbjct: 170 HELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIMNGRIANPPTDKSDRDMLDVL 229 Query: 359 IDSKYKNGR-QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEV 535 I K + G + + E+TG+ I+ +FAG HTSS T++WT L++ + +A ++E E Sbjct: 230 IAVKAETGTPRFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDE- 288 Query: 536 MKRHGDKIDHDILAEMDVLYRCIKE 610 + G + L ++ L +KE Sbjct: 289 LYGDGRSVSFHALRQIPQLENVLKE 313
>CP51_UNCNE (O14442) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 524 Score = 118 bits (296), Expect = 1e-26 Identities = 71/208 (34%), Positives = 113/208 (54%), Gaps = 9/208 (4%) Frame = +2 Query: 14 SYVDRMVAEAEEYFSKW----GESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSA 181 SYV + E E Y + GESGTV++ + + I TAS L G EVRE +A Sbjct: 161 SYVTIIQNEVEAYINNCVSFQGESGTVNISKVMAEITIYTASHALQGEEVRENFDSSFAA 220 Query: 182 LFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSR---KASGQSEEDMLQ 352 L+HDLD G PI+ F + P+P +R RD A+ +A + II++R K SG+++ D++ Sbjct: 221 LYHDLDMGFTPINFTFYWAPLPWNRARDHAQRTVARTYMNIIQARREEKRSGENKHDIMW 280 Query: 353 CFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKE 532 + S YK+G + E+ ++IA L AGQH+SS TS+W +L E EEQ Sbjct: 281 ELMRSTYKDGTPVPDREIAHMMIALLMAGQHSSSSTSSWIMLWLAARPDIMEELYEEQLR 340 Query: 533 VM--KRHGDKIDHDILAEMDVLYRCIKE 610 + ++ + ++ L+++ + +KE Sbjct: 341 IFGSEKPFPPLQYEDLSKLQLHQNVLKE 368
>CP51_MYCVN (Q5IZM4) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 452 Score = 117 bits (294), Expect = 2e-26 Identities = 66/205 (32%), Positives = 115/205 (56%), Gaps = 4/205 (1%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 ++ + + AE + WGESG +DL L I T++ CL+G + R +L + + Sbjct: 111 MKGHATTIEAEVRKMIEGWGESGEIDLLEFFAELTIYTSTACLIGLKFRNQLDSRFANYY 170 Query: 188 HDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKAS---GQSEEDMLQCF 358 H L+ G P+ + PYLPI + R RD+AR L E+ ++ R A+ +S+ DML Sbjct: 171 HLLERGTDPLCYVDPYLPIESFRIRDEARAGLVELVQDVMHGRIANPPKDKSDRDMLDVL 230 Query: 359 IDSKYKNGR-QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEV 535 + K ++G + T +E+TG+ I+ +FAG HTSS TS+WT LL+ +++A+ V+++ + Sbjct: 231 VSIKDEDGNPRFTANEITGMFISLMFAGHHTSSGTSSWTLIELLRHPEFYAK-VQQELDD 289 Query: 536 MKRHGDKIDHDILAEMDVLYRCIKE 610 + G ++ L ++ L +KE Sbjct: 290 LYADGQEVSFHALRQIPSLDNALKE 314
>CP51_ASHGO (Q759W0) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 529 Score = 111 bits (277), Expect = 2e-24 Identities = 67/209 (32%), Positives = 109/209 (52%), Gaps = 9/209 (4%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFS-------KWGESGTVDLKYELEHLIILTASRCLLGREVREKLFD 169 R YV ++ E +Y SG V++ + I TASR LLG E+ L Sbjct: 162 RRYVPMVMDEVRKYLRTSKHFMMNERSSGVVNVMETQPEMTIFTASRSLLGAEMHSMLDA 221 Query: 170 DVSALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATII-KSRKASGQSEEDM 346 D + L+ DLD G P++ +F LP+ +RRRD A+ ++ + +I + RK + + D+ Sbjct: 222 DFAYLYADLDKGFTPLNFVFRDLPLDNYRRRDNAQRTISSTYMKVIERRRKNNDVQDRDL 281 Query: 347 LQCFIDS-KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEE 523 + + S +YK+G + T+ ++ LLI L GQHTS+ TS W +L + E EE Sbjct: 282 IDALMTSAQYKDGVKMTDQQIANLLIGVLMGGQHTSAATSAWVLLHLAERPDIQEELYEE 341 Query: 524 QKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 Q V+ ++ +++L EM +L + IKE Sbjct: 342 QMRVLDGGAKELTYELLQEMPLLNQVIKE 370
>CP51_ISSOR (Q02315) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) (Fragment) Length = 414 Score = 109 bits (273), Expect = 5e-24 Identities = 64/203 (31%), Positives = 112/203 (55%), Gaps = 5/203 (2%) Frame = +2 Query: 17 YVDRMVAEAEEYFSK--WGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFH 190 YV + E +YF+ G+SG D+ + + TASR L G +R +L + ++ Sbjct: 104 YVPLIKDEMLKYFNANFRGDSGKTDVLKSQSEMTLFTASRSLFGDALRNRLDASYAEMYS 163 Query: 191 DLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQ-SEEDMLQCFI-D 364 DLD G P++ +F YLP+P + +RD A ++ + +I +++A G+ ED++ + + Sbjct: 164 DLDKGFTPLNFVFSYLPLPNYWKRDAAHKNISNTYLDLINTKRAGGEIKNEDLVDALLKN 223 Query: 365 SKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKR 544 S YK+G + T+ E+ L+I L GQHTSS TS W +L + Q E E + V+ Sbjct: 224 SVYKDGTRMTDEELAHLMIGVLMGGQHTSSATSAWFLLHLGEKPQLQEEIYREIQSVLGE 283 Query: 545 HGDK-IDHDILAEMDVLYRCIKE 610 + ++ + +D L ++D++ IKE Sbjct: 284 NFERELTYDDLQKLDLVNATIKE 306
>CP51_CANTR (P14263) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 109 bits (273), Expect = 5e-24 Identities = 67/216 (31%), Positives = 113/216 (52%), Gaps = 13/216 (6%) Frame = +2 Query: 2 NKLRSYVDRMVAEAEEYF-------SKWGESGTVDLKYELEHLIILTASRCLLGREVREK 160 + ++YV ++ E YF +K + G + + I TASRCL G E+R+ Sbjct: 153 DSFKTYVPKIREEVLNYFVNDVSFKTKERDHGVASVMKTQPEITIFTASRCLFGDEMRKS 212 Query: 161 LFDDVSALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASG--QS 334 + L+ DLD G PI+ +FP LP+P + RRD A+ +++ + IK R+ SG Sbjct: 213 FDRSFAQLYADLDKGFTPINFVFPNLPLPHYWRRDAAQRKISAHYMKEIKRRRESGDIDP 272 Query: 335 EEDML-QCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAE 511 + D++ ++S YK+G + T+ E+ LLI L GQHTS+ TS W +L + Q + Sbjct: 273 KRDLIDSLLVNSTYKDGVKMTDQEIANLLIGVLMGGQHTSASTSAWFLLHLAEQPQLQDD 332 Query: 512 AVEEQKEVMKRHG---DKIDHDILAEMDVLYRCIKE 610 EE ++K G + + ++ L ++ ++ IKE Sbjct: 333 LYEELTNLLKEKGGDLNDLTYEDLQKLPLVNNTIKE 368
>CP51_CANAL (P10613) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Lanosterol 14-alpha demethylase) (P450-14DM) Length = 528 Score = 97.1 bits (240), Expect = 4e-20 Identities = 64/208 (30%), Positives = 103/208 (49%), Gaps = 6/208 (2%) Frame = +2 Query: 5 KLRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSAL 184 K+R + E + K G ++ + I TASR L G E+R + L Sbjct: 161 KIREEILNYFVTDESFKLKEKTHGVANVMKTQPEITIFTASRSLFGDEMRRIFDRSFAQL 220 Query: 185 FHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSE--EDML-QC 355 + DLD G PI+ +FP LP+P + RRD A+ +++ + IKSR+ G + D++ Sbjct: 221 YSDLDKGFTPINFVFPNLPLPHYWRRDAAQKKISATYMKEIKSRRERGDIDPNRDLIDSL 280 Query: 356 FIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEV 535 I S YK+G + T+ E+ LLI L GQHTS+ TS W +L + +E E+ Sbjct: 281 LIHSTYKDGVKMTDQEIANLLIGILMGGQHTSASTSAWFLLHLGEKPHLQDVIYQEVVEL 340 Query: 536 MKRHG---DKIDHDILAEMDVLYRCIKE 610 +K G + + ++ L ++ + IKE Sbjct: 341 LKEKGGDLNDLTYEDLQKLPSVNNTIKE 368
>CP51_PENIT (Q12664) Cytochrome P450 51 (EC 1.14.13.70) (CYPLI) (P450-LIA1)| (Sterol 14-alpha demethylase) (Eburicol 14-alpha-demethylase) (P450-14DM) Length = 515 Score = 87.0 bits (214), Expect = 4e-17 Identities = 52/167 (31%), Positives = 79/167 (47%), Gaps = 13/167 (7%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKW----GESGTVDLKYELEHLIILTASRCLLGREVREKLFDDV 175 L SYV + E Y G+SGT+DL + + I TA+R L G EVR KL + Sbjct: 149 LESYVPLIADETNAYIKSSPNFKGQSGTIDLAAAMAEITIFTAARTLQGEEVRSKLTSEF 208 Query: 176 SALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKS---------RKASG 328 + LFHDLD G PI+ + P+ P+P + + T ++ + R+ Sbjct: 209 ADLFHDLDLGFSPINFMLPWAPLPHNASAIKHTTYARDLSGNYPSATGSWRRRQRRRQDK 268 Query: 329 QSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTW 469 DM+ + Y++G + E+ ++I L AGQH+SS S W Sbjct: 269 SKGTDMISNLMRCVYRDGTPIPDKEIAHMMITLLMAGQHSSSAISCW 315
>KAO2_ARATH (Q9C5Y2) Ent-kaurenoic acid oxidase 2 (EC 1.14.13.79) (AtKAO2)| (Cytochrome P450 88A4) Length = 489 Score = 63.2 bits (152), Expect = 6e-10 Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 7/208 (3%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 L Y+ + KW + G ++ L L L E E + D + + Sbjct: 156 LSVYIQFIEETVNTDLEKWSKMGEIEFLSHLRKLTFKVIMYIFLSSE-SEHVMDSLEREY 214 Query: 188 HDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKAS-----GQSEEDMLQ 352 +L+ G+ + + P A+ R +AR +L F +I+ +R+ + +DML Sbjct: 215 TNLNYGVRAMGINLPGF---AYHRALKARKKLVAAFQSIVTNRRNQRKQNISSNRKDMLD 271 Query: 353 CFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKE 532 ID K +NGR + E+ LL+ L AG +S + W + + +A EEQ+ Sbjct: 272 NLIDVKDENGRVLDDEEIIDLLLMYLNAGHESSGHLTMWATILMQEHPMILQKAKEEQER 331 Query: 533 VMKRH--GDKIDHDILAEMDVLYRCIKE 610 ++K+ G K+ EM L + I E Sbjct: 332 IVKKRAPGQKLTLKETREMVYLSQVIDE 359
>C85A1_ORYSA (Q8GSQ1) Cytochrome P450 85A1 (EC 1.14.-.-) (C6-oxidase) (OsDWARF)| (Dwarf protein) Length = 469 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/179 (22%), Positives = 82/179 (45%), Gaps = 3/179 (1%) Frame = +2 Query: 14 SYVDRMVAEAEEYFSKWGESGT---VDLKYELEHLIILTASRCLLGREVREKLFDDVSAL 184 S + ++ A + + W S + VD++ + + + +L+A R + G L D + A Sbjct: 142 SLLPKIDAFMRSHLAAWSSSSSSAVVDIQAKTKEMALLSALRQIAGVSAGP-LSDALKAE 200 Query: 185 FHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFID 364 + L G + + + LP + + +AR +L + +I R++SGQ +DML + Sbjct: 201 LYTLVLGTISLPI---NLPGTNYYQGFKARKKLVAMLEQMIAERRSSGQVHDDMLDALLT 257 Query: 365 SKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMK 541 + T+ ++ L+I +++G T S TS YL + + +E ++ K Sbjct: 258 GVEGTREKLTDEQIIDLIITLIYSGYETMSTTSMMAVKYLSDHPKALEQLRKEHFDIRK 316
>C85A1_ARATH (Q9FMA5) Cytochrome P450 85A1 (EC 1.14.-.-)| (Brassinosteroid-6-oxidase 1) (BR6ox 1) (C6-oxidase 1) Length = 465 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/145 (24%), Positives = 69/145 (47%) Frame = +2 Query: 50 YFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFHDLDNGMMPISVIF 229 Y +W E +D++ + +H+ L++ + G +R+ ++ F L G + + + Sbjct: 154 YLDQWNELEVIDIQDKTKHMAFLSSLTQIAGN-LRKPFVEEFKTAFFKLVVGTLSVPID- 211 Query: 230 PYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVT 409 LP +R QAR + + +++ R+ SG++ DML ++ K N T+ E+ Sbjct: 212 --LPGTNYRCGIQARNNIDRLLRELMQERRDSGETFTDMLG-YLMKKEGNRYPLTDEEIR 268 Query: 410 GLLIAALFAGQHTSSITSTWTGAYL 484 ++ L++G T S TS YL Sbjct: 269 DQVVTILYSGYETVSTTSMMALKYL 293
>KAO1_HORVU (Q9AXH9) Ent-kaurenoic acid oxidase 1 (EC 1.14.13.79) (gpr5)| Length = 499 Score = 50.4 bits (119), Expect = 4e-06 Identities = 39/182 (21%), Positives = 80/182 (43%), Gaps = 7/182 (3%) Frame = +2 Query: 17 YVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFHDL 196 ++D V +S+ G G + EL + + +G E+ ++ + +L Sbjct: 163 FIDDTVVTTLRGWSERGGDGHFEFLTELRRMTFRIIVQIFMGG-ADERTAAELERTYTEL 221 Query: 197 DNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASG-------QSEEDMLQC 355 + GM +++ P A+ + +AR RL ++ R+A G + DM+ Sbjct: 222 NYGMRAMAIDLPGF---AYHKAIRARRRLVAALQRVLDERRARGGKTAAGAAAPVDMMDR 278 Query: 356 FIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEV 535 I + + GR+ + E+ +L+ L AG +S + W +L + + A+A EQ+ + Sbjct: 279 LIAVEDEGGRRLQDDEIIDVLVMYLNAGHESSGHITMWATVFLQENPEILAKAKAEQEAI 338 Query: 536 MK 541 M+ Sbjct: 339 MR 340
>C85A2_ARATH (Q940V4) Cytochrome P450 85A2 (EC 1.14.-.-)| (Brassinosteroid-6-oxidase 2) (BR6ox 2) (C6-oxidase 2) Length = 465 Score = 50.1 bits (118), Expect = 5e-06 Identities = 38/165 (23%), Positives = 74/165 (44%) Frame = +2 Query: 50 YFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFHDLDNGMMPISVIF 229 Y W + TVD++ + +H+ L+ S + +++ ++ F L G + + + Sbjct: 154 YLCGWDDLETVDIQEKTKHMAFLS-SLLQIAETLKKPEVEEYRTEFFKLVVGTLSVPID- 211 Query: 230 PYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVT 409 +P +R QAR + + +++ RK SG++ DML ++ K N T+ E+ Sbjct: 212 --IPGTNYRSGVQARNNIDRLLTELMQERKESGETFTDMLG-YLMKKEDNRYLLTDKEIR 268 Query: 410 GLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKR 544 ++ L++G T S TS YL + E E + +R Sbjct: 269 DQVVTILYSGYETVSTTSMMALKYLHDHPKALEELRREHLAIRER 313
>C85A1_LYCES (Q43147) Cytochrome P450 85A1 (EC 1.14.-.-) (C6-oxidase) (Dwarf| protein) Length = 464 Score = 49.3 bits (116), Expect = 9e-06 Identities = 43/188 (22%), Positives = 91/188 (48%), Gaps = 6/188 (3%) Frame = +2 Query: 23 DRMVAEAEEYF----SKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFH 190 D+++ + +E+ + W ++ +D++ + + L++ + + G E L + + F Sbjct: 141 DQLLPKIDEFMRSHLTNW-DNKVIDIQEKTNKMAFLSSLKQIAGIE-STSLAQEFMSEFF 198 Query: 191 DLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSK 370 +L G + + + LP + R QAR + + T+I+ R+AS + + DML ++ ++ Sbjct: 199 NLVLGTLSLPI---NLPNTNYHRGFQARKIIVNLLRTLIEERRASKEIQHDMLG-YLMNE 254 Query: 371 YKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEV--MKR 544 + T+ E+ L+I L++G T S TS YL + E +E + K+ Sbjct: 255 EATRFKLTDDEMIDLIITILYSGYETVSTTSMMAVKYLHDHPKVLEELRKEHMAIREKKK 314 Query: 545 HGDKIDHD 568 D ID++ Sbjct: 315 PEDPIDYN 322
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/201 (22%), Positives = 85/201 (42%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 L SY+ +M + Y +WG++ V +L + A+ +G +V + + F Sbjct: 117 LDSYLPKMDGIVQGYLEQWGKANEVIWYPQLRRMTFDVAATLFMGEKVSQN--PQLFPWF 174 Query: 188 HDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDS 367 G+ + + LP + +AR L IIK+R+ SEED L + + Sbjct: 175 ETYIQGLFSLPIP---LPNTLFGKSQRARALLLAELEKIIKARQQQPPSEEDALGILLAA 231 Query: 368 KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRH 547 + N + + E+ ++ LFAG T +TS + LL Q Q++ + Sbjct: 232 RDDNNQPLSLPELKDQILLLLFAGHET--LTSALSSFCLLLGQHSDIRERVRQEQNKLQL 289 Query: 548 GDKIDHDILAEMDVLYRCIKE 610 ++ + L +M L + ++E Sbjct: 290 SQELTAETLKKMPYLDQVLQE 310
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 46.6 bits (109), Expect = 6e-05 Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 15/143 (10%) Frame = +2 Query: 227 FPYLPIPAHRRRDQARTRLAEIFATIIKSRKAS--GQSEEDMLQC--------FID---- 364 F Y P RR +A + + +I+ R+ + Q +D LQ FID Sbjct: 245 FLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLL 304 Query: 365 SKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMK- 541 S+ KNG++ ++ ++ +F G T++ +W L + +Y +E +E++K Sbjct: 305 SEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKD 364 Query: 542 RHGDKIDHDILAEMDVLYRCIKE 610 R +I+ D LA++ L C+KE Sbjct: 365 REPKEIEWDDLAQLPFLTMCLKE 387
>C85A_PHAVU (Q69F95) Cytochrome P450 85A (EC 1.14.-.-) (C6-oxidase)| Length = 466 Score = 46.2 bits (108), Expect = 7e-05 Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = +2 Query: 236 LPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGL 415 LP +R QAR + I + +++ RKAS DML C + K +N + ++ E+ L Sbjct: 211 LPRTNYRGGLQARKSIISILSQLLEERKASQDVHVDMLGCLM-KKDENRYKLSDEEIIDL 269 Query: 416 LIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEV--MKRHGDKIDHDILAEM 583 +I +++G T S TS YL + E +E + K+ D ID + L M Sbjct: 270 VITIMYSGYETVSTTSMMAVKYLHDHPKVLEEIRKEHFAIRERKKPEDPIDCNDLKSM 327
>CP26B_HUMAN (Q9NR63) Cytochrome P450 26B1 (EC 1.14.-.-) (P450 26A2) (P450| retinoic acid-inactivating 2) (P450RAI-2) (Retinoic-acid metabolizing cytochrome) Length = 512 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 3/184 (1%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESG-TVDLKYELEHLIILTASRCLLGREVREKLFDDVSAL 184 L SY+ ++ ++ W +++ E + L A R LLG + E +D+ L Sbjct: 154 LESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSIPE---EDLGHL 210 Query: 185 FHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEE--DMLQCF 358 F + + + LP +RR QAR L + I+ + Q ++ D L Sbjct: 211 FEVYQQFVDNVFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQGKDYLDALDLL 270 Query: 359 IDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVM 538 I+S ++G++ T E+ + +FA T++ ST LLK +E+ ++ + Sbjct: 271 IESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLK----HPTVLEKLRDEL 326 Query: 539 KRHG 550 + HG Sbjct: 327 RAHG 330
>C76B1_HELTU (O23976) Cytochrome P450 76B1 (EC 1.14.-.-) (7-ethoxycoumarin| O-deethylase) (ECOD) (Phenylurea dealkylase) Length = 490 Score = 43.9 bits (102), Expect = 4e-04 Identities = 40/162 (24%), Positives = 75/162 (46%), Gaps = 5/162 (3%) Frame = +2 Query: 140 GREVREKLFDDVSALFHDLDNGMMPISVIFPYLPI--PAHRRRDQAR--TRLAEIFATII 307 G+E RE + + + +D+ + +FP L P +R AR +++ IF +I Sbjct: 196 GKEFREVITNIM------VDSAKTNLVDVFPVLKKIDPQGIKRGMARHFSKVLGIFDQLI 249 Query: 308 KSRKASGQSEE-DMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYL 484 + R +G+ E+ D+L + N + + + L + AG T+SIT W L Sbjct: 250 EERMRTGRFEQGDVLDVCLKMMQDNPNEFNHTNIKALFLDLFVAGTDTTSITIEWAMTEL 309 Query: 485 LKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 L+ ++A EE ++V+ + G + D + + L +KE Sbjct: 310 LRKPHIMSKAKEELEKVIGK-GSIVKEDDVLRLPYLSCIVKE 350
>C71BH_ARATH (Q9LTM6) Cytochrome P450 71B17 (EC 1.14.-.-)| Length = 502 Score = 43.9 bits (102), Expect = 4e-04 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 23/225 (10%) Frame = +2 Query: 5 KLRSYVDRMVAEAEEYFSKWGESGT----VDLKYELEHLIILTASRCLLGREVREKLFDD 172 KL+S++ E K ES VDL L L R G+ E F D Sbjct: 138 KLQSFIYIKEVECNFLVKKLSESAVDQSPVDLSKTLFWLAASILFRVAFGQSFHESEFTD 197 Query: 173 VSALFH-----DLDNGMMPISVIFPYLPIP--------AHRRRDQARTRLAEIFATIIKS 313 + + G S FP + H+R + +L + +I Sbjct: 198 TDKIDELVFETETAQGSFTCSDFFPIAGLGWLVDWISGQHKRLNDVFLKLDALLQHVIDD 257 Query: 314 RKASGQSEE--DMLQCFIDSKYKNGR----QTTESEVTGLLIAALFAGQHTSSITSTWTG 475 G+S++ D++ +D +K G+ + T + GLL + AG T ++T WT Sbjct: 258 HSNPGRSKDHKDIVDVMLDVMHKQGKDDSLRLTIDHIKGLLTNIIIAGIDTGALTMIWTM 317 Query: 476 AYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 L + + + E ++ + + ++I + L ++ L IKE Sbjct: 318 TELARNPEIMKKVQGEIRDRLGNNRERITKEDLDKVPFLNLVIKE 362
>C71BE_ARATH (P58051) Cytochrome P450 71B14 (EC 1.14.-.-)| Length = 496 Score = 43.1 bits (100), Expect = 6e-04 Identities = 26/75 (34%), Positives = 38/75 (50%) Frame = +2 Query: 386 QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDH 565 Q T + G+L+ L AG TS T TW +L+K + +A E +EV+K D + Sbjct: 281 QLTRNHTKGILLNVLIAGVDTSGHTVTWVMTHLIKNPRVMKKAQAEVREVIKNKDDITEE 340 Query: 566 DILAEMDVLYRCIKE 610 DI ++ L IKE Sbjct: 341 DI-ERLEYLKMVIKE 354
>C71BD_ARATH (P58050) Cytochrome P450 71B13 (EC 1.14.-.-)| Length = 496 Score = 43.1 bits (100), Expect = 6e-04 Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 6/126 (4%) Frame = +2 Query: 251 HRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGR------QTTESEVTG 412 H + ++ F IK G S++D++ + K + G Q T + G Sbjct: 232 HNKCEKVFKGTDSFFDHCIKHHLEDGGSKDDIVDLLL--KVERGEIGLGEFQFTRNHTKG 289 Query: 413 LLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVL 592 +L+ L AG TS T TW +L+K + +A E +EV+K + D I + + ++ L Sbjct: 290 ILLDILLAGVDTSGHTITWVMTHLIKNPRVMKKAQAEVREVIK-NKDNITEEDIEGLEYL 348 Query: 593 YRCIKE 610 +KE Sbjct: 349 KMVVKE 354
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 42.7 bits (99), Expect = 8e-04 Identities = 29/134 (21%), Positives = 62/134 (46%), Gaps = 17/134 (12%) Frame = +2 Query: 260 RDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSKY----------------KNGRQT 391 + +A R+ E+ + R+ + +D+LQ + + KNG ++ Sbjct: 239 KQEATERMRELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKS 298 Query: 392 TESE-VTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHD 568 + + G L AG T++ T+++T L + + +A E+ + +++HG K+ +D Sbjct: 299 MSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYD 358 Query: 569 ILAEMDVLYRCIKE 610 +++M L CI E Sbjct: 359 AISDMKYLEACILE 372
>C135A_MYCTU (O08447) Putative cytochrome P450 135A1 (EC 1.14.-.-)| Length = 449 Score = 42.4 bits (98), Expect = 0.001 Identities = 42/167 (25%), Positives = 75/167 (44%), Gaps = 12/167 (7%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 LR Y D + + A E+ ++W T++ L+H+ LT ++ R V V A Sbjct: 116 LRGYRDMIASVAREHITRWRPHATIN---SLDHMNALTLD--IILRVVFGVTDPKVKA-- 168 Query: 188 HDLDNGMMPISVIFPYL----PIPAHRRRD------QARTRLAEIFATIIKSRKASGQ-- 331 +L + + I I P + P P+ +R + +T++ EI I SR+ Sbjct: 169 -ELTSRLQQIINIHPAILAGVPYPSLKRMNPWKRFFHNQTKIDEILYREIASRRIDSDLT 227 Query: 332 SEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWT 472 + D+L + +K + T++E+ LI L AG T++ +WT Sbjct: 228 ARTDVLSRLLQTKDTPTKPLTDAELRDQLITLLLAGHETTAAALSWT 274
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 41.6 bits (96), Expect = 0.002 Identities = 51/225 (22%), Positives = 90/225 (40%), Gaps = 24/225 (10%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKW----GESGTVDLKYELEHLIILTASRCLLGREVREKL---F 166 L+ YV M KW G+ T+++ + + + T +C +E +L + Sbjct: 153 LKPYVGIMADSVRIMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSQEGSVQLDRKY 212 Query: 167 DDVSALFHDLDN-GMMPISVIFPYLPI----PAHRRRDQARTRLA-EIFATIIKSRKASG 328 DL+N I IF I ++ R+ ++ +LA E +IKSRKA Sbjct: 213 KSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRKARSAWQLAHEHTDQVIKSRKAQL 272 Query: 329 QSEE-----------DMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTG 475 Q EE D L + ++ +NG ++ ++ + +F G T++ +W Sbjct: 273 QDEEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFMFEGHDTTASGISWI- 331 Query: 476 AYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 Y L + ++ + + G I D L +M CIKE Sbjct: 332 FYALATNPEHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKE 376
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 40.8 bits (94), Expect = 0.003 Identities = 24/89 (26%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = +2 Query: 302 IIKSRKASGQSEEDMLQCFIDS-KYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGA 478 ++ +RKAS +D+L ++ + G + ++ +T LI L AG T+S T ++ Sbjct: 221 VVAARKASPSDRKDLLAAMLNGVDPQTGEKLSDENITNQLITFLIAGHETTSGTLSFAMY 280 Query: 479 YLLKFQQYFAEAVEEQKEVMKRHGDKIDH 565 LLK + +++ +E EV+ R ++H Sbjct: 281 QLLKNPEAYSKVQKEVDEVVGRGPVLVEH 309
>C71BB_ARATH (P58049) Cytochrome P450 71B11 (EC 1.14.-.-)| Length = 496 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/75 (33%), Positives = 36/75 (48%) Frame = +2 Query: 386 QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDH 565 Q T G+L L AG TS+ TW YL+ + +A E +EV+K D I+ Sbjct: 281 QLTRDNTKGILFNILNAGIDTSAQVMTWVMTYLISNPRVMKKAQAEVREVIKNKDDIIEE 340 Query: 566 DILAEMDVLYRCIKE 610 DI ++ L +KE Sbjct: 341 DI-ERLEYLKMVVKE 354
>C71B5_ARATH (O65784) Cytochrome P450 71B5 (EC 1.14.-.-)| Length = 498 Score = 40.4 bits (93), Expect = 0.004 Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 6/121 (4%) Frame = +2 Query: 266 QARTRLAEIFATIIKSRKASGQSEE--DMLQCFIDSKYK----NGRQTTESEVTGLLIAA 427 +A ++L F +I SG+ E+ D++ +D K + T+ + GL+ Sbjct: 237 KAFSKLTNFFELVIDDHLKSGKIEDHSDIISVMLDMINKPTEVGSYKVTDDHLKGLMSDV 296 Query: 428 LFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIK 607 AG + SIT WT L + + + EE + + + +KI + L +++ L I+ Sbjct: 297 FLAGVNAGSITMIWTMTELSRHPRVMRKLQEEIRAALGPNKEKITEEDLEKVEYLKMVIE 356 Query: 608 E 610 E Sbjct: 357 E 357
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 40.0 bits (92), Expect = 0.005 Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 14/148 (9%) Frame = +2 Query: 191 DLDNGMMPISVIFPYL-PIPAHRRRDQARTRLAEIFATI---IKSRKASGQSEE--DMLQ 352 DL N + + +FP+ PI + T + + F IKS + +G S D LQ Sbjct: 215 DLFNPLFLLVALFPFTGPILEKMKFSFFPTAVTDFFYASLAKIKSGRDTGNSTNRVDFLQ 274 Query: 353 CFIDSKYKNGRQTTESEVTGLL--------IAALFAGQHTSSITSTWTGAYLLKFQQYFA 508 IDS+ + +T E + GL + +FAG TSS T ++ AY L + Sbjct: 275 LMIDSQKGSDTKTGEEQTKGLTDHEILSQAMIFIFAGYETSSSTMSFL-AYNLATNHHVM 333 Query: 509 EAVEEQKEVMKRHGDKIDHDILAEMDVL 592 ++E+ + + + I ++ L +MD L Sbjct: 334 TKLQEEIDTVFPNKAPIQYEALMQMDYL 361
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/111 (23%), Positives = 48/111 (43%) Frame = +2 Query: 278 RLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSI 457 R+ +I + R+ +G+ D+L ++ + + + L AG HTSS+ Sbjct: 253 RIRDIVWRAVHLREKTGEKRNDLLDYLMELRTSETSKLDGDDFVAQAFGFLVAGFHTSSM 312 Query: 458 TSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 T T+ L Q A E K+V++ H K+ + + +M L + E Sbjct: 313 TLTFALYELSVHQDIQTTARTEIKDVLEHHKKKVTYYSIKDMKYLDMVVNE 363
>C71BC_ARATH (Q9ZU07) Cytochrome P450 71B12 (EC 1.14.-.-)| Length = 496 Score = 39.7 bits (91), Expect = 0.007 Identities = 26/75 (34%), Positives = 35/75 (46%) Frame = +2 Query: 386 QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDH 565 Q T G+L L AG TS+ TW YL+ + +A E +EV+K D I+ Sbjct: 281 QLTRDHTKGILANILNAGIDTSAQVMTWVMTYLISNPRVLKKAQAEVREVIKHKDDIIEE 340 Query: 566 DILAEMDVLYRCIKE 610 DI + L IKE Sbjct: 341 DI-ERLQYLKMVIKE 354
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 39.7 bits (91), Expect = 0.007 Identities = 33/140 (23%), Positives = 61/140 (43%), Gaps = 15/140 (10%) Frame = +2 Query: 233 YLPIPAHRRRDQARTRLAEIFATIIKSR----KASGQSEEDMLQCFIDSKYKNGRQTTES 400 YLP ++R + + ++ II R KA E+D+L ++S + ++ Sbjct: 253 YLPTKRNKRMKEINKEITDMLRFIINKRMKALKAGEPGEDDLLGVLLESNIQEIQKQGNK 312 Query: 401 EVTGLLIAAL--------FAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVM---KRH 547 + G+ I + FAGQ T+ + TWT L K ++ A EE + K Sbjct: 313 KDGGMSINDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPE 372 Query: 548 GDKIDHDILAEMDVLYRCIK 607 ++++H M +LY ++ Sbjct: 373 FERLNHLKYVSM-ILYEVLR 391
>CP26A_HUMAN (O43174) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic| acid-metabolizing cytochrome) (P450 retinoic acid-inactivating 1) (P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) Length = 497 Score = 39.3 bits (90), Expect = 0.009 Identities = 48/215 (22%), Positives = 86/215 (40%), Gaps = 14/215 (6%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKW---GESGTVDLKYELEHLIILTASRCLLGREVREKLFDD-- 172 L YV + E +W GE G + + E++ L+ A R LLG E + D Sbjct: 149 LECYVPVITEEVGSSLEQWLSCGERGLL-VYPEVKRLMFRIAMRILLGCEPQLAGDGDSE 207 Query: 173 --VSALFHDLDNGMMPISVIFPYLPI-PAHRRRDQARTRLAEIFATIIKSRKAS--GQSE 337 + F ++ + + + P+ + + R+ R+ + I +AS GQ Sbjct: 208 QQLVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGC 267 Query: 338 EDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAV 517 +D LQ I+ ++ G + + LF G T++ +T YL + + Sbjct: 268 KDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVR 327 Query: 518 EEQKE----VMKRHGDKIDHDILAEMDVLYRCIKE 610 EE K +K+D +IL ++ + IKE Sbjct: 328 EELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKE 362
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 39.3 bits (90), Expect = 0.009 Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 1/120 (0%) Frame = +2 Query: 254 RRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALF 433 RRR + + F KS+ D + + SK ++G+ ++ ++ +F Sbjct: 274 RRRTLPTQGIDDFFKDKAKSKTL------DFIDVLLLSKDEDGKALSDEDIRAEADTFMF 327 Query: 434 AGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMK-RHGDKIDHDILAEMDVLYRCIKE 610 G T++ +W L + +Y +E +E++K R +I+ D LA++ L C+KE Sbjct: 328 GGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKE 387
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 38.9 bits (89), Expect = 0.012 Identities = 48/228 (21%), Positives = 88/228 (38%), Gaps = 27/228 (11%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIIL----TASRCLLG----------- 142 L+ YV M KW + D E+ H + L T +C Sbjct: 149 LKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNS 208 Query: 143 REVREKLFDDVSALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLA-EIFATIIKSRK 319 R + + D + +F + + S+I+ + + R + ++A E +IK+RK Sbjct: 209 RSYTKAVEDLNNLIFFRVRSAFYGNSIIYN---MSSDGRLSRRACQIAHEHTDGVIKTRK 265 Query: 320 ASGQSEE-----------DMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITST 466 A Q+EE D L + +K ++G+ ++ ++ + +F G T++ + Sbjct: 266 AQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGIS 325 Query: 467 WTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 W Y L E E+ + + G + D L +M CIKE Sbjct: 326 WV-FYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKE 372
>CP26A_CHICK (Q9PUB4) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) Length = 492 Score = 38.1 bits (87), Expect = 0.020 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 5/164 (3%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKY-ELEHLIILTASRCLLGREVREKLFDDVSAL 184 L+ YV + E ++W +G L Y E++ L+ A R LLG + R+ D L Sbjct: 149 LQHYVPVIQEEVSACLAQWLGAGPCLLVYPEVKRLMFRIAMRILLGFQPRQASPDGEQQL 208 Query: 185 ---FHDLDNGMMPISVIFPYLPI-PAHRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQ 352 F ++ + + + P+ + R R+ ++ E + ++ G +D LQ Sbjct: 209 VEAFEEMIRNLFSLPIDVPFSGLYRGLRARNIIHAKIEENIRAKMARKEPEG-GYKDALQ 267 Query: 353 CFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYL 484 ++ NG Q E+ LF G T++ +T A+L Sbjct: 268 LLMEHTQGNGEQLNMQELKESATELLFGGHETTASAATSLIAFL 311
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 38.1 bits (87), Expect = 0.020 Identities = 40/187 (21%), Positives = 79/187 (42%), Gaps = 10/187 (5%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGT---VDLKYELEHLIILTASRCLLGREV----REKLF 166 ++ Y MV A + KW +++ ++ L + T C R++ Sbjct: 112 MKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPH 171 Query: 167 DDVSALFHDLDNGMMPISVIFPYLPI-PAHRRRDQARTRLA-EIFATIIKSRKASGQSEE 340 ++++ LD M + P P ++R+ Q ++ ++ II RKASG+ + Sbjct: 172 PFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSD 231 Query: 341 DMLQCFIDSK-YKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAV 517 D+L ++ K + G + + +I L AG T+S ++ +L+K +A Sbjct: 232 DLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAA 291 Query: 518 EEQKEVM 538 EE V+ Sbjct: 292 EEAARVL 298
>CPXN_ANASP (P29980) Probable cytochrome P450 110 (EC 1.14.-.-)| Length = 459 Score = 38.1 bits (87), Expect = 0.020 Identities = 19/65 (29%), Positives = 33/65 (50%) Frame = +2 Query: 296 ATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTG 475 A I + R + D+L + ++ +NG+ T+ E+ L+ LFAG T++ T W Sbjct: 215 AEIEEKRTKENEQRGDVLSLMMAARDENGQAMTDEELKDELLTILFAGHETTATTIAWAF 274 Query: 476 AYLLK 490 +LK Sbjct: 275 YQILK 279
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 37.7 bits (86), Expect = 0.026 Identities = 55/222 (24%), Positives = 91/222 (40%), Gaps = 19/222 (8%) Frame = +2 Query: 2 NKLRSYVDRMVAEAE---EYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREK---- 160 N + S+V + EA +++ + G ++L EL A++ +G EVR + Sbjct: 136 NAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQITMGDEVRNQANYQ 195 Query: 161 ---LFDDVSALFHDLDNGMMPISVIFPYLP-------IPAHRRRDQARTRLAEIFATII- 307 L + AL N ++PI V+ P+L +RR +A T+ II Sbjct: 196 NGNLLESYKAL-----NNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIKDIID 250 Query: 308 KSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLL 487 K ++ S E L I + + G + + +V G +FA T SIT + Sbjct: 251 KKLSSTDNSSEPALIDRILNLVRIG-ELSYDDVMGEFSNIIFAASDTLSITVNNVLILMA 309 Query: 488 KFQQYFAEAVEEQKEVMKRHGD-KIDHDILAEMDVLYRCIKE 610 F +Y EE EV G+ + H L ++ L R + E Sbjct: 310 MFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHE 351
>C71B8_ARATH (P58048) Cytochrome P450 71B8 (EC 1.14.-.-)| Length = 506 Score = 37.4 bits (85), Expect = 0.034 Identities = 27/126 (21%), Positives = 54/126 (42%), Gaps = 6/126 (4%) Frame = +2 Query: 251 HRRRDQARTRLAEIFATIIKSRKASGQSEE------DMLQCFIDSKYKNGRQTTESEVTG 412 H R ++A ++L + F +I GQS++ ML S + T + Sbjct: 236 HSRIEKAFSKLTKFFQHVIDEELKIGQSQDHSNLVSSMLDMINRSTEYGSFKITSDHLIA 295 Query: 413 LLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVL 592 ++ + G + +IT WT L + + + EE + + + ++I + L +++ L Sbjct: 296 MMTDIVLGGVNAGTITMIWTMTELTRHPRVMKKLREEIRATLGPNKERITEEDLEKVEYL 355 Query: 593 YRCIKE 610 IKE Sbjct: 356 KLVIKE 361
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 36.2 bits (82), Expect = 0.077 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 6/108 (5%) Frame = +2 Query: 305 IKSRKASGQ--SEEDMLQCFIDSKYKNGRQT----TESEVTGLLIAALFAGQHTSSITST 466 IKS + + Q S D LQ IDS+ +G Q T+ E+ + +FAG TSS + T Sbjct: 255 IKSNREASQQKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFIFAGYETSSSSLT 314 Query: 467 WTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 + AY L + ++E+ + + + + L EM+ L I E Sbjct: 315 FL-AYNLATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINE 361
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 36.2 bits (82), Expect = 0.077 Identities = 32/108 (29%), Positives = 51/108 (47%), Gaps = 6/108 (5%) Frame = +2 Query: 305 IKSRKASGQ--SEEDMLQCFIDSKYKNGRQT----TESEVTGLLIAALFAGQHTSSITST 466 IKS + + Q S D LQ IDS+ +G Q T+ E+ + +FAG TSS + T Sbjct: 255 IKSNREASQQKSRVDFLQLMIDSQKNSGAQQDKSLTDHEILSQSMIFIFAGYETSSSSLT 314 Query: 467 WTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 + AY L + ++E+ + + + + L EM+ L I E Sbjct: 315 FL-AYNLATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINE 361
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 36.2 bits (82), Expect = 0.077 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 11/114 (9%) Frame = +2 Query: 302 IIKSRKASGQSEE-----------DMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHT 448 +IK RKA Q+EE D L + +K ++G+ ++ ++ + +F G T Sbjct: 263 VIKMRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDT 322 Query: 449 SSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 ++ +W Y L E E+ + + G + D L ++ CIKE Sbjct: 323 TASGISWV-FYALATHPEHQERCREEVQSILGDGTSVTWDHLDQIPYTTMCIKE 375
>C71AC_ARATH (O49340) Cytochrome P450 71A12 (EC 1.14.-.-)| Length = 497 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/111 (19%), Positives = 46/111 (41%), Gaps = 2/111 (1%) Frame = +2 Query: 284 AEIFATIIKSRKASGQSEEDMLQCF--IDSKYKNGRQTTESEVTGLLIAALFAGQHTSSI 457 +++ +++ +G +ED + I+S+ G Q ++ +++ G TSS Sbjct: 246 SDLMDKVVQEHLEAGNHKEDFVDILLSIESEKSIGFQAQRDDIKFMILDMFIGGTSTSST 305 Query: 458 TSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 W L++ + +E + ++ HG I + M L IKE Sbjct: 306 LLEWIMTELIRNPNVMKKLQDEIRSTIRPHGSYIKEKDVENMKYLKAVIKE 356
>C71D7_SOLCH (P93531) Cytochrome P450 71D7 (EC 1.14.-.-)| Length = 500 Score = 35.0 bits (79), Expect = 0.17 Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 17/173 (9%) Frame = +2 Query: 143 REVREKLFDDVSALFHDLDNGMMPISVIFPYLPI-----PAHRRRDQARTRLAEIFATII 307 +EV KL +V +L D ++ IFP A ++ A ++ I +I Sbjct: 195 QEVFIKLIREVISLAEGFD-----VADIFPSYKFLHGFGGAKQKLLNAHRKVDSIVEDVI 249 Query: 308 KSRK---ASGQSE-----EDMLQCFIDSKYKNGRQ--TTESEVTGLLIAALFAGQHTSSI 457 K K A+ +S+ ED++ + Q + ++I AG TSS Sbjct: 250 KEHKKNLATRKSDDAIGGEDLVDALVRLMNDKSLQFPINNDNIKAVIIDLFAAGTETSST 309 Query: 458 TSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKI--DHDILAEMDVLYRCIKE 610 T+ W A +LK FA+A Q +V + DK+ D + + E+ L IKE Sbjct: 310 TTVWAMAEMLKNPSVFAKA---QAKVREAFRDKVTFDENDVEELKYLKLVIKE 359
>C724B_ORYSA (Q6F4F5) Cytochrome P450 724B1 (EC 1.14.-.-) (OsDWARF11) (Dwarf| protein 11) Length = 480 Score = 35.0 bits (79), Expect = 0.17 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = +2 Query: 221 VIFP-YLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEE-DMLQCFIDSKYKNGRQTT 394 + FP Y+P + + QAR R++ II+ R+ +G S + D L + S + + Sbjct: 220 ISFPLYIPGTPYAKAVQARARISSTVKGIIEERRNAGSSNKGDFLDVLLSS-----NELS 274 Query: 395 ESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKI 559 + E ++ +L G T+S+ L+ YF + E++KR + I Sbjct: 275 DEEKVSFVLDSLLGGYETTSL--------LISMVVYFLGQSAQDLELVKREHEGI 321
>CP26A_XENLA (O93323) Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid| degrading enzyme CYP26) (xCYP26) (Retinoic acid-converting enzyme) (RACE) Length = 492 Score = 35.0 bits (79), Expect = 0.17 Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 8/167 (4%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYE-LEHLIILTASRCLLG-------REVREKL 163 L +YV +M E + W +SG L Y ++ ++ A R LLG RE E L Sbjct: 149 LANYVPQMEEEVRCSVNLWLQSGPCVLVYPAIKRMMFRIAMRLLLGCDPQRMDREQEETL 208 Query: 164 FDDVSALFHDLDNGMMPISVIFPYLPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEED 343 + + +L + +PI V F L R R+ ++ E K ++ + +D Sbjct: 209 LEAFEEMSRNLFS--LPIDVPFSGL-YRGLRARNLIHAQIEENIKE--KLQREPDEHCKD 263 Query: 344 MLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYL 484 LQ ID +NG + LF G T++ +T ++L Sbjct: 264 ALQLLIDYSRRNGEPINLQALKESATELLFGGHGTTASAATSLTSFL 310
>C6A20_DROME (Q9V773) Probable cytochrome P450 6a20 (EC 1.14.-.-) (CYPVIA20)| Length = 501 Score = 34.7 bits (78), Expect = 0.22 Identities = 31/112 (27%), Positives = 45/112 (40%), Gaps = 5/112 (4%) Frame = +2 Query: 290 IFATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAA-----LFAGQHTSS 454 I + R + D + I+ K K E+ +T IAA AG TSS Sbjct: 252 IIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFFLAGFETSS 311 Query: 455 ITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 T + L Q + E V+K+H K+D+D + EM L + I E Sbjct: 312 TTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVIDE 363
>C75A4_GENTR (Q96581) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A4) Length = 516 Score = 34.3 bits (77), Expect = 0.29 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 1/108 (0%) Frame = +2 Query: 251 HRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFI-DSKYKNGRQTTESEVTGLLIAA 427 H++ D TRL + + RK + D L I + +G + + LL+ Sbjct: 251 HKKFDVLLTRLLDDHKRTSQERK----QKPDFLDFVIANGDNSDGERLNTDNIKALLLNL 306 Query: 428 LFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDI 571 AG TSS W A LLK + A +E V+ R ++ DI Sbjct: 307 FTAGTDTSSSIIEWALAELLKNRTLLTRAQDEMDRVIGRDRRLLESDI 354
>CP10_LYMST (P48416) Cytochrome P450 10 (EC 1.14.-.-) (CYPX)| Length = 545 Score = 33.9 bits (76), Expect = 0.38 Identities = 21/78 (26%), Positives = 38/78 (48%) Frame = +2 Query: 377 NGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDK 556 NG +T+ EVTGL++ + A T+S + W L K Q + +E E ++ Sbjct: 333 NGSMSTK-EVTGLIVDLMLAAVETTSSATVWCLYNLAKNPQVQEKLFQEITEAQAKNNGT 391 Query: 557 IDHDILAEMDVLYRCIKE 610 I + L ++ ++ +KE Sbjct: 392 ISAEDLCKLPMVKAVVKE 409
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 33.5 bits (75), Expect = 0.50 Identities = 20/111 (18%), Positives = 47/111 (42%), Gaps = 2/111 (1%) Frame = +2 Query: 284 AEIFATIIKSRKASGQSEEDMLQCF--IDSKYKNGRQTTESEVTGLLIAALFAGQHTSSI 457 +++ +++ +G+ + D + I+ + NG + +++ +++ G TSS Sbjct: 246 SDLMEKVVQEHLEAGEHKADFVNILLSIEKEKNNGFKVQRNDIKFMILDMFIGGISTSST 305 Query: 458 TSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 W L++ + + E + ++ HG I + M L IKE Sbjct: 306 LLEWIMTELIRNPECMKKLQNEIRSTIRPHGSYIKEKEVENMRYLKAVIKE 356
>C71BR_ARATH (Q9SAE1) Cytochrome P450 71B27 (EC 1.14.-.-)| Length = 503 Score = 33.5 bits (75), Expect = 0.50 Identities = 24/97 (24%), Positives = 39/97 (40%) Frame = +2 Query: 320 ASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQ 499 +SG ML +K+ + + +L+ AG T +IT W L+K Sbjct: 267 SSGDIVALMLDMIKKKGHKDDFKLNVDNIKAVLMNIFLAGIDTGAITMIWAMTELVKKPL 326 Query: 500 YFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 A E + V+ D+I + L + D L +KE Sbjct: 327 VMKRAQENIRGVLGLKRDRITEEDLCKFDCLKHIVKE 363
>C76C1_ARATH (O64636) Cytochrome P450 76C1 (EC 1.14.-.-)| Length = 512 Score = 33.1 bits (74), Expect = 0.65 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 7/118 (5%) Frame = +2 Query: 278 RLAEIFATIIKSRKASGQSEEDMLQC----FIDS--KYKNGR-QTTESEVTGLLIAALFA 436 RL +F I ++ A S+ + F+D+ YK + + S++ LL+ A Sbjct: 252 RLVRVFRGFIDAKIAEKSSQNNPKDVSKNDFVDNLLDYKGDESELSISDIEHLLLDMFTA 311 Query: 437 GQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 G TSS T W LLK + A+A E V+ ++G + DI +++ L +KE Sbjct: 312 GTDTSSSTLEWAMTELLKNPKTMAKAQAEIDCVIGQNGIVEESDI-SKLPYLQAVVKE 368
>C71B1_THLAR (P49264) Cytochrome P450 71B1 (EC 1.14.-.-) (CYPLXXIB1)| Length = 496 Score = 33.1 bits (74), Expect = 0.65 Identities = 22/75 (29%), Positives = 37/75 (49%) Frame = +2 Query: 386 QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDH 565 + T G+L+ L AG TS+ T TW +LL + + E +E +K + D+I Sbjct: 281 ELTREHTKGILMNILTAGIDTSAQTMTWAMTHLLANPRVMKKLQAEIREKIK-NIDEITD 339 Query: 566 DILAEMDVLYRCIKE 610 D + ++D +KE Sbjct: 340 DDVEQLDYFKLVLKE 354
>C75A7_EUSGR (O04790) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A7) Length = 510 Score = 33.1 bits (74), Expect = 0.65 Identities = 31/108 (28%), Positives = 41/108 (37%), Gaps = 1/108 (0%) Frame = +2 Query: 251 HRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFI-DSKYKNGRQTTESEVTGLLIAA 427 H++ D TRL E RK S D L + + G + + LL+ Sbjct: 247 HKKFDALLTRLLEEHTASAHERKGS----PDFLDFVVANGDNSEGERLQTVNIKALLLNM 302 Query: 428 LFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDI 571 AG TSS W A LLK A EE V+ R ++ DI Sbjct: 303 FTAGTDTSSSVIEWALAELLKNPIILRRAQEEMDGVIGRDRRFLEADI 350
>C75A5_EUSGR (Q96418) Flavonoid 3',5'-hydroxylase (EC 1.14.13.88) (F3'5'H)| (Cytochrome P450 75A5) Length = 510 Score = 33.1 bits (74), Expect = 0.65 Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 1/108 (0%) Frame = +2 Query: 251 HRRRDQARTRLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKN-GRQTTESEVTGLLIAA 427 H++ D TRL E RK S D L + ++ + G + + LL+ Sbjct: 247 HKKFDALLTRLLEEHTASAHERKGS----PDFLDFVVANRDNSEGERLHTVNIKALLLNM 302 Query: 428 LFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDI 571 AG TSS W A LLK A EE V+ R ++ DI Sbjct: 303 FTAGTDTSSSVIEWALAELLKNPIILKRAQEEMDGVIGRDRRFLEADI 350
>C71AD_ARATH (O49342) Cytochrome P450 71A13 (EC 1.14.-.-)| Length = 497 Score = 32.7 bits (73), Expect = 0.85 Identities = 35/175 (20%), Positives = 70/175 (40%), Gaps = 13/175 (7%) Frame = +2 Query: 125 SRCLLGREVREKLFDDVSALFHDLDNGMMPISVIFP---YLPIPA--------HRRRDQA 271 SR LGR+ E D+ + +M + FP Y+PI A + + + Sbjct: 185 SRVALGRKHSE---DETARDLKKRVRQIMELLGEFPIGEYVPILAWIDGIRGFNNKIKEV 241 Query: 272 RTRLAEIFATIIKSRKASGQSEEDMLQCFID-SKYKN-GRQTTESEVTGLLIAALFAGQH 445 +++ +++ + + D + + K KN G Q +++ +++ G Sbjct: 242 SRGFSDLMDKVVQEHLEASNDKADFVDILLSIEKDKNSGFQVQRNDIKFMILDMFIGGTS 301 Query: 446 TSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 T+S WT L++ + + +E + ++ HG I + M L IKE Sbjct: 302 TTSTLLEWTMTELIRSPKSMKKLQDEIRSTIRPHGSYIKEKEVENMKYLKAVIKE 356
>C71BN_ARATH (Q9LTM0) Cytochrome P450 71B23 (EC 1.14.-.-)| Length = 501 Score = 32.7 bits (73), Expect = 0.85 Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 4/94 (4%) Frame = +2 Query: 341 DMLQCFIDSKYKNGR----QTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFA 508 D++ ID K + + T + G++ AG +TS+ T W L++ + Sbjct: 268 DVVDVMIDMMNKQSQDGSFKLTTDHIKGIISDIFLAGVNTSATTILWAMTELIRNPRVMK 327 Query: 509 EAVEEQKEVMKRHGDKIDHDILAEMDVLYRCIKE 610 + +E + V+ D+I L +++ IKE Sbjct: 328 KVQDEVRTVLGEKRDRITEQDLNQLNYFKLVIKE 361
>CP39A_HUMAN (Q9NYL5) Cytochrome P450 39A1 (EC 1.14.13.99)| (24-hydroxycholesterol 7-alpha-hydroxylase) (Oxysterol 7-alpha-hydroxylase) (hCYP39A1) Length = 469 Score = 32.3 bits (72), Expect = 1.1 Identities = 45/210 (21%), Positives = 77/210 (36%), Gaps = 9/210 (4%) Frame = +2 Query: 8 LRSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALF 187 L + ++ E E G GT+DL + HL+ L + LF Sbjct: 132 LHQFTGQLTEELHEQLENLGTHGTMDLNNLVRHLLYPVTVNMLFNK----SLFSTNKKKI 187 Query: 188 HDLDNGMMPISVIFPY---LPIPAHRRRDQARTRLAEIFATIIKSRKASGQSEED---ML 349 + F Y LP R +++ E+F I KA ++++ +L Sbjct: 188 KEFHQYFQVYDEDFEYGSQLPECLLRNWSKSKKWFLELFEKNIPDIKACKSAKDNSMTLL 247 Query: 350 QCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQK 529 Q +D + S GLL+ L+A + + WT AY+L +E Sbjct: 248 QATLDI-VETETSKENSPNYGLLL--LWASLSNAVPVAFWTLAYVLSHPDIHKAIMEGIS 304 Query: 530 EVMKRHGD---KIDHDILAEMDVLYRCIKE 610 V + G K+ D L ++ ++ C+ E Sbjct: 305 SVFGKAGKDKIKVSEDDLEKLLLIKWCVLE 334
>RIC8_CAEBR (Q61A92) Synembryn (Resistance to inhibitors of cholinesterase| protein 8) Length = 567 Score = 32.0 bits (71), Expect = 1.4 Identities = 18/54 (33%), Positives = 28/54 (51%) Frame = +2 Query: 11 RSYVDRMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDD 172 R +++ A+ EE+FSKW S K+ + A R LLG E+ K+ +D Sbjct: 13 RVFLNATSAKIEEFFSKWNFSNANSTKFGMSE-----AERNLLGDEISAKIDND 61
>CP53_ASPNG (P17549) Benzoate 4-monooxygenase (EC 1.14.13.12)| (Benzoate-para-hydroxylase) (Cytochrome P450 53) (BpH) Length = 517 Score = 31.2 bits (69), Expect = 2.5 Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 11/112 (9%) Frame = +2 Query: 233 YLPIPAHRRRDQARTRLAEIFATIIKSRKA----SGQSEEDMLQCFIDSKYKNGRQTTES 400 YLP R QA LA I + R + + D+L ++ K NG + + Sbjct: 247 YLPDSFFRDGIQAVEDLAGIAVARVNERLRPEVMANNTRVDLLARLMEGKDSNGEKLGRA 306 Query: 401 EVTGLLIAALFAGQHTSSITST----W---TGAYLLKFQQYFAEAVEEQKEV 535 E+T + L AG T+S TS W T + K + EA+ + +V Sbjct: 307 ELTAEALTQLIAGSDTTSNTSCAILYWCMRTPGVIEKLHKALDEAIPQDVDV 358
>ERG5_YEAST (P54781) Cytochrome P450 61 (EC 1.14.14.-) (C-22 sterol desaturase)| Length = 538 Score = 31.2 bits (69), Expect = 2.5 Identities = 40/189 (21%), Positives = 72/189 (38%), Gaps = 16/189 (8%) Frame = +2 Query: 92 YELEHLIILTASRCLLGREVRE----KLFDDVSALFHDLDNGMMPISVIFPYLPIPAHRR 259 +E+ ++ + G + E K+ DD + L+ PI I PY ++ Sbjct: 209 HEMREILCALSLNSFCGNYITEDQVRKIADDYYLVTAALELVNFPI--IIPYTKTWYGKK 266 Query: 260 RDQARTRLAEIFATIIKSRKASGQSEEDMLQCFI----DSKYKNG-------RQTTESEV 406 ++ E A + K A+G ++ + D+K N R+ T E+ Sbjct: 267 TADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEI 326 Query: 407 TGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRH-GDKIDHDILAEM 583 + + LFA Q SS + W + A+ EEQ V +++ D++ +M Sbjct: 327 SEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKM 386 Query: 584 DVLYRCIKE 610 IKE Sbjct: 387 KYTNMVIKE 395
>C135B_MYCTU (P63715) Putative cytochrome P450 135B1 (EC 1.14.-.-)| Length = 472 Score = 31.2 bits (69), Expect = 2.5 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Frame = +2 Query: 251 HRRRDQARTRLAEIFATI---IKSRKASGQ--SEEDMLQCFIDSKYKNGRQTTESEVTGL 415 +R + R R+ E A + I R+A + D L + + ++GR TE E+ Sbjct: 195 NRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAADEDGRTMTERELRDQ 254 Query: 416 LIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVE 520 LI L AG T++ +W L + A+AV+ Sbjct: 255 LITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQ 289
>C135B_MYCBO (P63716) Putative cytochrome P450 135B1 (EC 1.14.-.-)| Length = 472 Score = 31.2 bits (69), Expect = 2.5 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Frame = +2 Query: 251 HRRRDQARTRLAEIFATI---IKSRKASGQ--SEEDMLQCFIDSKYKNGRQTTESEVTGL 415 +R + R R+ E A + I R+A + D L + + ++GR TE E+ Sbjct: 195 NRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAADEDGRTMTERELRDQ 254 Query: 416 LIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVE 520 LI L AG T++ +W L + A+AV+ Sbjct: 255 LITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQ 289
>BPAEB_HUMAN (Q8WXK8) Bullous pemphigoid antigen 1, isoform 7 (Bullous pemphigoid| antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin) (Fragment) Length = 3060 Score = 30.8 bits (68), Expect = 3.2 Identities = 23/70 (32%), Positives = 31/70 (44%) Frame = -2 Query: 477 APVQVEVMELVCCPANSAAISSPVTSLSVVWRPFLYLESMKHCSMSSSDCPEALRDLMIV 298 +PVQ E +E + + S IS +TS W E H S +D PE DL Sbjct: 2593 SPVQFENLEEIFDTSVSKEISDDITSDITSW------EGNTHFEESFTDGPEKELDLFTY 2646 Query: 297 AKISAKRVRA 268 K AK ++A Sbjct: 2647 LKHCAKNIKA 2656
>C71D6_SOLCH (P93530) Cytochrome P450 71D6 (EC 1.14.-.-)| Length = 501 Score = 30.8 bits (68), Expect = 3.2 Identities = 20/69 (28%), Positives = 33/69 (47%) Frame = +2 Query: 404 VTGLLIAALFAGQHTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDHDILAEM 583 + ++I AG TSS T+ W +LK + A+A E +E R+ D + + ++ Sbjct: 293 IKAIIIDMFAAGTETSSTTTVWAMVEMLKNPRVLAKAQAEVREAF-RNKVTFDENDVEDL 351 Query: 584 DVLYRCIKE 610 L IKE Sbjct: 352 KYLKLVIKE 360
>WRK10_ARATH (Q9LG05) Probable WRKY transcription factor 10 (WRKY DNA-binding| protein 10) Length = 506 Score = 30.8 bits (68), Expect = 3.2 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Frame = +2 Query: 173 VSALFHDLDNGMMPISVIFPYLPIPA-HRRRDQARTRLAEIFATIIKSRKASGQSEEDM 346 + A+ DNG+ PIS IFP +P H + R+ L E A + + +EE+M Sbjct: 26 ILAMLEQTDNGLNPISEIFPQESLPRDHTDQSGQRSGLRERLAARVGFNLPTLNTEENM 84
>SYA_LISIN (Q92BK9) Alanyl-tRNA synthetase (EC 6.1.1.7) (Alanine--tRNA ligase)| (AlaRS) Length = 879 Score = 30.0 bits (66), Expect = 5.5 Identities = 23/96 (23%), Positives = 39/96 (40%) Frame = +2 Query: 278 RLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSI 457 +L + I+ S +++ D +Q I ++ + +T GL I + Sbjct: 327 KLVPVVGKIMNSFYPEVENQTDFIQKVIRTEEERFHETLNE---GLAILETILKNAKETN 383 Query: 458 TSTWTGAYLLKFQQYFAEAVEEQKEVMKRHGDKIDH 565 T GA + K F VE +E + HG K+DH Sbjct: 384 EQTIKGADIFKLYDTFGFPVELTEEYAEDHGLKVDH 419
>A85B_MYCAV (Q06947) Antigen 85-B precursor (85B) (Extracellular alpha-antigen)| (Antigen 85 complex B) (Ag85B) (Mycolyl transferase 85B) (EC 2.3.1.-) (Fibronectin-binding protein B) Length = 330 Score = 29.6 bits (65), Expect = 7.2 Identities = 19/53 (35%), Positives = 29/53 (54%) Frame = -2 Query: 285 AKRVRAWSRRRCAGIGR*GKMTLIGIIPLSRSWKRAETSSNNFSRTSLPNKHL 127 +++VRAW RR G +TL G+I L+ ++N FSR LP ++L Sbjct: 5 SEKVRAWGRRLLVGAA--AAVTLPGLIGLA----GGAATANAFSRPGLPVEYL 51
>C71D9_SOYBN (O81971) Cytochrome P450 71D9 (EC 1.14.-.-) (P450 CP3)| Length = 496 Score = 29.6 bits (65), Expect = 7.2 Identities = 20/81 (24%), Positives = 34/81 (41%) Frame = +2 Query: 308 KSRKASGQSEEDMLQCFIDSKYKNGRQTTESEVTGLLIAALFAGQHTSSITSTWTGAYLL 487 KS Q EE++L +D K ++ + ++ G TSS T TW A ++ Sbjct: 259 KSSATGDQGEEEVL---LDVLLKKEFGLSDESIKAVIWDIFGGGSDTSSATITWAMAEMI 315 Query: 488 KFQQYFAEAVEEQKEVMKRHG 550 K + + E + V + G Sbjct: 316 KNPRTMEKVQTEVRRVFDKEG 336
>CP2L1_PANAR (Q27712) Cytochrome P450 2L1 (EC 1.14.14.1) (CYPIIL1)| Length = 492 Score = 29.6 bits (65), Expect = 7.2 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 13/106 (12%) Frame = +2 Query: 281 LAEIFATIIKSRKAS--GQSEEDMLQCFI---DSKYKNGRQTTESEVTGLLIAALF-AGQ 442 L + T IK +A+ + +D+L ++ + ++ T E +I LF AG Sbjct: 241 LKDYMKTFIKEHQATLDPSNPKDLLDAYLIDLQERKEDPLSTMNIETVRAVIMDLFGAGT 300 Query: 443 HTSSITSTWTGAYLLKFQQYFAEAVEEQKEVMKR-------HGDKI 559 T+S WT YL+K+ + A+ E + R H DK+ Sbjct: 301 ETTSTMIRWTILYLMKYPEVQAKIQREIDAAVPRGTLPSLEHKDKL 346
>DPH2_CANGA (Q6FPD9) Diphthamide biosynthesis protein 2| Length = 551 Score = 29.3 bits (64), Expect = 9.4 Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 3/39 (7%) Frame = +2 Query: 464 TWTGAYLLKFQQYFAEAVEEQKEV---MKRHGDKIDHDI 571 TWTG +++ FQ+ E E+ +HG+ DHD+ Sbjct: 403 TWTGKWIIDFQKAITEIDNSLAELGIDDSKHGNDSDHDL 441 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,033,169 Number of Sequences: 219361 Number of extensions: 1750927 Number of successful extensions: 5245 Number of sequences better than 10.0: 85 Number of HSP's better than 10.0 without gapping: 5105 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5222 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5424720305 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
