Clone Information

BLAST Search Result

Clone Name	rbaal9c11
Clone Library Name	barley_pub

No.	Definition	Score (bits)	E Value
1	UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-...	190	4e-48
2	UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-...	186	6e-47
3	PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-...	150	3e-36
4	HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1...	135	9e-32
5	HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein...	135	9e-32
6	HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein...	135	9e-32
7	TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protei...	133	4e-31
8	TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (E...	127	3e-29
9	PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)	122	8e-28
10	TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-...	121	2e-27
11	PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)	117	4e-26
12	SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC...	116	7e-26
13	RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)	114	2e-25
14	PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-)	110	4e-24
15	SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC...	110	4e-24
16	ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-)	110	5e-24
17	ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (E...	110	5e-24
18	NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like prot...	108	1e-23
19	NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like prot...	108	1e-23
20	NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like prot...	108	1e-23
21	WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 ...	108	1e-23
22	WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 ...	108	1e-23
23	NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3....	108	2e-23
24	SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC...	107	2e-23
25	SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC...	107	2e-23
26	NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)	106	7e-23
27	SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of de...	105	9e-23
28	WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 ...	105	9e-23
29	NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2...	105	9e-23
30	WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 ...	105	9e-23
31	NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)	105	2e-22
32	SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3....	96	1e-19
33	UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (...	88	2e-17
34	UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (...	84	4e-16
35	K0317_MOUSE (Q8CHG5) Protein KIAA0317	84	4e-16
36	K0317_HUMAN (O15033) Protein KIAA0317	84	4e-16
37	HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6...	82	2e-15
38	UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-)	78	3e-14
39	UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-)	77	4e-14
40	HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3	77	5e-14
41	HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6...	75	2e-13
42	HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6...	74	3e-13
43	UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB f...	73	9e-13
44	TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TR...	72	1e-12
45	HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing...	69	1e-11
46	HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing...	69	1e-11
47	YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protei...	68	3e-11
48	HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing...	63	7e-10
49	HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT do...	61	4e-09
50	HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (P...	58	2e-08
51	EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hy...	58	3e-08
52	EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (...	58	3e-08
53	EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (...	58	3e-08
54	HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing...	52	2e-06
55	MUT7_CAEEL (P34607) Probable exonuclease mut-7 (EC 3.1.-.-)	30	5.1
56	FBN3_HUMAN (Q75N90) Fibrillin-3 precursor	30	5.1
57	GLMM_PHOLL (Q7MYY3) Phosphoglucosamine mutase (EC 5.4.2.10)	30	5.1
58	CENB2_HUMAN (Q15057) Centaurin-beta 2 (Cnt-b2)	30	5.1

>UPL2_ARATH (Q8H0T4) E3 ubiquitin protein ligase UPL2 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 2)
          Length = 3658

 Score =  190 bits (482), Expect = 4e-48
 Identities = 88/106 (83%), Positives = 96/106 (90%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y+ Y++ SPVI+WFWE+V+ FSKED ARFLQFVTGTSKVPLEGF ALQGISGPQR QIHK
Sbjct: 3552 YTSYTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHK 3611

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 347
            AYGS   LPSAHTCFNQLDLPEY SK+Q+QERLLLAIHEANEGFGF
Sbjct: 3612 AYGSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEGFGF 3657

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>UPL1_ARATH (Q8GY23) E3 ubiquitin protein ligase UPL1 (EC 6.3.2.-)|
            (Ubiquitin-protein ligase 1)
          Length = 3684

 Score =  186 bits (472), Expect = 6e-47
 Identities = 87/106 (82%), Positives = 94/106 (88%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y+ Y+  SPVI WFWE+V+ FSKED ARFLQFVTGTSKVPLEGF ALQGISGPQR QIHK
Sbjct: 3575 YTSYTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHK 3634

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 347
            AYG+   LPSAHTCFNQLDLPEY SK+QLQERLLLAIHEA+EGFGF
Sbjct: 3635 AYGAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEASEGFGF 3680

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>PTR1_SCHPO (O13834) E3 ubiquitin protein ligase ptr1 (EC 6.3.2.-) (Poly(A)+ RNA|
            transport protein 1)
          Length = 3227

 Score =  150 bits (380), Expect = 3e-36
 Identities = 66/106 (62%), Positives = 84/106 (79%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y GY+++SP +QWFW  V+ F +E++A+ LQF TGTSKVPL GF  L+G+SG QRF IHK
Sbjct: 3121 YHGYNVSSPQVQWFWRAVRSFDEEERAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHK 3180

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 347
            +YGS N LP +HTCFNQLDLPEY + +QL+  LL AI+E +EGFGF
Sbjct: 3181 SYGSLNRLPQSHTCFNQLDLPEYDTYEQLRSMLLTAINEGSEGFGF 3226

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>HUWE1_RAT (P51593) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
           (E3 ubiquitin protein ligase URE-B1) (Upstream
           regulatory element-binding protein 1) (Fragment)
          Length = 322

 Score =  135 bits (341), Expect = 9e-32
 Identities = 64/105 (60%), Positives = 81/105 (77%)
 Frame = -3

Query: 664 YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
           Y  Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVPL+GF+AL+G++G Q+FQIH+
Sbjct: 216 YHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHR 275

Query: 484 AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              ST+ LPSAHTCFNQLDLP Y S ++L+  LLLAI E +EGFG
Sbjct: 276 DDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG 320

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>HUWE1_HUMAN (Q7Z6Z7) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin
            ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1)
          Length = 4374

 Score =  135 bits (341), Expect = 9e-32
 Identities = 64/105 (60%), Positives = 81/105 (77%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVPL+GF+AL+G++G Q+FQIH+
Sbjct: 4268 YHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHR 4327

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
               ST+ LPSAHTCFNQLDLP Y S ++L+  LLLAI E +EGFG
Sbjct: 4328 DDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG 4372

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>HUWE1_MOUSE (Q7TMY8) HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-)|
            (E3 ubiquitin protein ligase URE-B1) (E3Histone)
          Length = 4377

 Score =  135 bits (341), Expect = 9e-32
 Identities = 64/105 (60%), Positives = 81/105 (77%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y   S  IQWFW  ++ F + D+A+FLQFVTGTSKVPL+GF+AL+G++G Q+FQIH+
Sbjct: 4271 YHKYQSNSIQIQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHR 4330

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
               ST+ LPSAHTCFNQLDLP Y S ++L+  LLLAI E +EGFG
Sbjct: 4331 DDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLAIQECSEGFG 4375

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>TOM1_NEUCR (Q9P4Z1) E3 ubiquitin protein ligase TOM1-like protein (EC 6.3.2.-)|
          Length = 4065

 Score =  133 bits (335), Expect = 4e-31
 Identities = 61/106 (57%), Positives = 77/106 (72%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  YS  +P IQWFW  V+ F KE+ A+ LQFVTGTSKVPL GF  L+G++G  RF IH+
Sbjct: 3959 YHNYSAGAPQIQWFWRAVRSFDKEELAKLLQFVTGTSKVPLNGFKELEGMNGVSRFNIHR 4018

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 347
             YGS + LPS+HTCFNQLDLPEY + + L+ +LL AI   ++ FGF
Sbjct: 4019 DYGSKDRLPSSHTCFNQLDLPEYENYETLRSQLLKAITAGSDYFGF 4064

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>TOM1_ASHGO (Q756G2) Probable E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
          Length = 3258

 Score =  127 bits (319), Expect = 3e-29
 Identities = 59/105 (56%), Positives = 75/105 (71%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+     I +FW  V+ F KE++A+ LQFVTGTSKVPL GF  L G++G  +F IH+
Sbjct: 3152 YVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHR 3211

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
             YGS + LPS+HTCFNQLDLP Y S + L+  LLLAI+E +EGFG
Sbjct: 3212 DYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFG 3256

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>PUB3_SCHPO (O14326) E3 ubiquitin--protein ligase pub3 (EC 6.3.2.-)|
          Length = 786

 Score =  122 bits (307), Expect = 8e-28
 Identities = 58/105 (55%), Positives = 75/105 (71%)
 Frame = -3

Query: 664 YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
           Y  Y    PVI+WFWEI+ G+  ED+++ LQF TGTS++P+ GF  LQG  GP++F I K
Sbjct: 682 YRTYIATDPVIKWFWEIIAGWKNEDRSKLLQFATGTSRIPVNGFRDLQGSDGPRKFTIEK 741

Query: 484 AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
           A G+ + LP AHTCFN+LDLP+Y SKD L E+L LA+ E   GFG
Sbjct: 742 A-GTPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAV-ENTVGFG 784

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>TOM1_YEAST (Q03280) E3 ubiquitin protein ligase TOM1 (EC 6.3.2.-)|
            (Temperature-dependent organization in mitotic nucleus
            protein 1) (Suppressor of snRNA protein 2)
          Length = 3268

 Score =  121 bits (304), Expect = 2e-27
 Identities = 55/105 (52%), Positives = 74/105 (70%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+     + +FW  V+ F  E++A+ LQFVTGTSKVPL GF  L G++G  +F IH+
Sbjct: 3162 YVNYTATCKEVSYFWRAVRSFDAEERAKLLQFVTGTSKVPLNGFKELSGVNGVCKFSIHR 3221

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
             +GS+  LPS+HTCFNQL+LP Y S + L+  LLLAI+E +EGFG
Sbjct: 3222 DFGSSERLPSSHTCFNQLNLPPYESYETLRGSLLLAINEGHEGFG 3266

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>PUB1_SCHPO (Q92462) E3 ubiquitin--protein ligase pub1 (EC 6.3.2.-)|
          Length = 767

 Score =  117 bits (292), Expect = 4e-26
 Identities = 56/107 (52%), Positives = 71/107 (66%)
 Frame = -3

Query: 664 YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
           Y  YS    +I+WFWE++  +S E K+R LQF TGTS++P+ GF  LQG  GP++F I K
Sbjct: 663 YRSYSENDQIIKWFWELMDEWSNEKKSRLLQFTTGTSRIPVNGFKDLQGSDGPRKFTIEK 722

Query: 484 AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGFG 344
           A G  N LP AHTCFN+LDLP YTSK  L  +L +A+ E     GFG
Sbjct: 723 A-GEPNKLPKAHTCFNRLDLPPYTSKKDLDHKLSIAVEET---IGFG 765

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>SMUF2_HUMAN (Q9HAU4) Smad ubiquitination regulatory factor 2 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF2) (Smad-specific E3
           ubiquitin ligase 2) (hSMURF2)
          Length = 748

 Score =  116 bits (290), Expect = 7e-26
 Identities = 51/92 (55%), Positives = 71/92 (77%)
 Frame = -3

Query: 643 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNH 464
           S +++WFW+ V+ F +E +AR LQFVTG+S+VPL+GF ALQG +GP+ F IH+    TN+
Sbjct: 650 SNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNN 709

Query: 463 LPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 368
           LP AHTCFN++D+P Y S ++L E+LL AI E
Sbjct: 710 LPKAHTCFNRIDIPPYESYEKLYEKLLTAIEE 741

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>RSP5_YEAST (P39940) E3 ubiquitin--protein ligase RSP5 (EC 6.3.2.-)|
          Length = 809

 Score =  114 bits (286), Expect = 2e-25
 Identities = 53/107 (49%), Positives = 70/107 (65%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y GY  +  VIQWFW+ V  +  E +AR LQF TGTS++P+ GF  LQG  GP+RF I K
Sbjct: 705  YRGYQESDEVIQWFWKCVSEWDNEQRARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEK 764

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGFG 344
            A G    LP +HTCFN++DLP+Y   D ++++L LA+ E     GFG
Sbjct: 765  A-GEVQQLPKSHTCFNRVDLPQYVDYDSMKQKLTLAVEET---IGFG 807

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>PUB2_SCHPO (Q9UTG2) E3 ubiquitin--protein ligase pub2 (EC 6.3.2.-)|
          Length = 671

 Score =  110 bits (275), Expect = 4e-24
 Identities = 50/105 (47%), Positives = 71/105 (67%)
 Frame = -3

Query: 664 YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
           Y  Y+    ++ WFWE++  +S E KA+ LQF TGTS++PL GF  + G  GP++F I K
Sbjct: 567 YRSYTETDDIVIWFWELLSEWSPEKKAKLLQFATGTSRLPLSGFKDMHGSDGPRKFTIEK 626

Query: 484 AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
             G  + LP AHTCFN+LD+P Y SK++L+++L +AI E   GFG
Sbjct: 627 V-GHISQLPKAHTCFNRLDIPPYNSKEELEQKLTIAIQE-TAGFG 669

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>SMUF1_XENLA (Q9PUN2) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase) (xSMURF1)
          Length = 731

 Score =  110 bits (275), Expect = 4e-24
 Identities = 49/97 (50%), Positives = 72/97 (74%), Gaps = 3/97 (3%)
 Frame = -3

Query: 643 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQ---GISGPQRFQIHKAYGS 473
           S ++QWFW+ V+ F +E +AR LQFVTG+++VPL+GF ALQ   G +GP+ F IH    +
Sbjct: 630 SNIVQWFWQAVESFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDAN 689

Query: 472 TNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEAN 362
           T++LP AHTCFN++D+P Y S ++L E+LL A+ E +
Sbjct: 690 TDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETS 726

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>ITCH_MOUSE (Q8C863) Itchy E3 ubiquitin protein ligase (EC 6.3.2.-)|
          Length = 864

 Score =  110 bits (274), Expect = 5e-24
 Identities = 55/105 (52%), Positives = 70/105 (66%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+  S  I WFW+ V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I K
Sbjct: 760  YRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEK 819

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              G  N LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 820  V-GKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 862

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>ITCH_HUMAN (Q96J02) Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-)|
            (Itch) (Atrophin-1-interacting protein 4) (AIP4)
            (NFE2-associated polypeptide 1) (NAPP1)
          Length = 903

 Score =  110 bits (274), Expect = 5e-24
 Identities = 55/105 (52%), Positives = 70/105 (66%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+  S  I WFW+ V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I K
Sbjct: 799  YRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEK 858

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              G  N LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 859  V-GKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 901

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>NED4L_MOUSE (Q8CFI0) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 1004

 Score =  108 bits (270), Expect = 1e-23
 Identities = 54/103 (52%), Positives = 71/103 (68%)
 Frame = -3

Query: 661  SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKA 482
            +GY    PVIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F I + 
Sbjct: 900  NGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQ- 958

Query: 481  YGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            +GS   LP AHTCFN+LDLP Y + + L+E+LL+A+  A +GF
Sbjct: 959  WGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENA-QGF 1000

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>NED4L_PONPY (Q5RBF2) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
          Length = 959

 Score =  108 bits (270), Expect = 1e-23
 Identities = 54/103 (52%), Positives = 71/103 (68%)
 Frame = -3

Query: 661  SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKA 482
            +GY    PVIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F I + 
Sbjct: 855  NGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQ- 913

Query: 481  YGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            +GS   LP AHTCFN+LDLP Y + + L+E+LL+A+  A +GF
Sbjct: 914  WGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENA-QGF 955

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>NED4L_HUMAN (Q96PU5) E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-)|
            (Nedd4-2) (NEDD4.2)
          Length = 975

 Score =  108 bits (270), Expect = 1e-23
 Identities = 54/103 (52%), Positives = 71/103 (68%)
 Frame = -3

Query: 661  SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKA 482
            +GY    PVIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F I + 
Sbjct: 871  NGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQ- 929

Query: 481  YGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            +GS   LP AHTCFN+LDLP Y + + L+E+LL+A+  A +GF
Sbjct: 930  WGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENA-QGF 971

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>WWP2_MOUSE (Q9DBH0) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2)
          Length = 870

 Score =  108 bits (270), Expect = 1e-23
 Identities = 54/105 (51%), Positives = 72/105 (68%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+ +S  IQWFW++V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I +
Sbjct: 766  YRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDR 825

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              G    LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 826  V-GKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEE-TEGFG 868

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>WWP2_HUMAN (O00308) NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW|
            domain-containing protein 2) (Atrophin-1-interacting
            protein 2) (AIP2)
          Length = 870

 Score =  108 bits (270), Expect = 1e-23
 Identities = 55/105 (52%), Positives = 71/105 (67%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+  S  IQWFW++V+    E + R LQFVTGT ++P+ GF+ L G +GPQ+F I K
Sbjct: 766  YRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDK 825

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              G    LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 826  V-GKETWLPRSHTCFNRLDLPPYKSYEQLREKLLYAIEE-TEGFG 868

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>NEDD4_DROME (Q9VVI3) E3 ubiquitin-protein ligase Nedd-4 (EC 6.3.2.-) (DNedd4)|
          Length = 1007

 Score =  108 bits (269), Expect = 2e-23
 Identities = 55/105 (52%), Positives = 72/105 (68%), Gaps = 1/105 (0%)
 Frame = -3

Query: 664  YSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIH 488
            Y G Y +   +IQWFW  V  FS E ++R LQFVTGTS+VP+ GF  L G +GPQ F I 
Sbjct: 901  YKGDYHMNHIIIQWFWRAVLSFSNEMRSRLLQFVTGTSRVPMNGFKELYGSNGPQMFTIE 960

Query: 487  KAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            K +G+ N+ P AHTCFN+LDLP Y    QL+++L+ AI E ++GF
Sbjct: 961  K-WGTPNNFPRAHTCFNRLDLPPYEGYLQLKDKLIKAI-EGSQGF 1003

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>SMUF1_MOUSE (Q9CUN6) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase 1)
          Length = 731

 Score =  107 bits (268), Expect = 2e-23
 Identities = 48/95 (50%), Positives = 71/95 (74%), Gaps = 3/95 (3%)
 Frame = -3

Query: 643 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQ---GISGPQRFQIHKAYGS 473
           S +++WFW+ V+ F +E +AR LQFVTG+++VPL+GF ALQ   G +GP+ F IH    +
Sbjct: 630 SNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDAN 689

Query: 472 TNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 368
           T++LP AHTCFN++D+P Y S ++L E+LL A+ E
Sbjct: 690 TDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 724

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>SMUF1_HUMAN (Q9HCE7) Smad ubiquitination regulatory factor 1 (EC 6.3.2.-)|
           (Ubiquitin--protein ligase SMURF1) (Smad-specific E3
           ubiquitin ligase 1) (hSMURF1)
          Length = 757

 Score =  107 bits (268), Expect = 2e-23
 Identities = 48/95 (50%), Positives = 71/95 (74%), Gaps = 3/95 (3%)
 Frame = -3

Query: 643 SPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQ---GISGPQRFQIHKAYGS 473
           S +++WFW+ V+ F +E +AR LQFVTG+++VPL+GF ALQ   G +GP+ F IH    +
Sbjct: 656 SNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDAN 715

Query: 472 TNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 368
           T++LP AHTCFN++D+P Y S ++L E+LL A+ E
Sbjct: 716 TDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 750

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>NEDD4_RAT (Q62940) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 887

 Score =  106 bits (264), Expect = 7e-23
 Identities = 52/103 (50%), Positives = 71/103 (68%)
 Frame = -3

Query: 661  SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKA 482
            +GYS+   VI WFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F + + 
Sbjct: 783  NGYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ- 841

Query: 481  YGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            +G+ + LP AHTCFN+LDLP Y S D+L ++L +AI E  +GF
Sbjct: 842  WGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAI-ENTQGF 883

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>SUDX_DROME (Q9Y0H4) E3 ubiquitin-protein ligase suppressor of deltex (EC|
            6.3.2.-)
          Length = 949

 Score =  105 bits (263), Expect = 9e-23
 Identities = 55/104 (52%), Positives = 67/104 (64%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+  S  + WFW+ V+    E +AR LQFVTGT +VP+ GF+ L G +GPQRF I K
Sbjct: 845  YRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEK 904

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
              G    LP +HTCFN+LDLP Y S DQL E+L  AI E  EGF
Sbjct: 905  V-GKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEE-TEGF 946

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>WWP1_MOUSE (Q8BZZ3) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1)
          Length = 918

 Score =  105 bits (263), Expect = 9e-23
 Identities = 55/105 (52%), Positives = 69/105 (65%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+  S  I WFW+ V+    E + R LQFVTGT ++PL GF+ L G +GPQ+F I K
Sbjct: 814  YRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEK 873

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              G    LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 874  V-GKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 916

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>NEDD4_MOUSE (P46935) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural|
            precursor cell expressed developmentally down-regulated
            protein 4)
          Length = 887

 Score =  105 bits (263), Expect = 9e-23
 Identities = 52/103 (50%), Positives = 71/103 (68%)
 Frame = -3

Query: 661  SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKA 482
            +GYS+   VI WFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F + + 
Sbjct: 783  NGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ- 841

Query: 481  YGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            +G+ + LP AHTCFN+LDLP Y S D+L ++L +AI E  +GF
Sbjct: 842  WGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAI-ENTQGF 883

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>WWP1_HUMAN (Q9H0M0) NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW|
            domain-containing protein 1) (Atropin-1-interacting
            protein 5) (AIP5)
          Length = 922

 Score =  105 bits (263), Expect = 9e-23
 Identities = 55/105 (52%), Positives = 69/105 (65%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y  Y+  S  I WFW+ V+    E + R LQFVTGT ++PL GF+ L G +GPQ+F I K
Sbjct: 818  YRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEK 877

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              G    LP +HTCFN+LDLP Y S +QL+E+LL AI E  EGFG
Sbjct: 878  V-GKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEE-TEGFG 920

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>NEDD4_HUMAN (P46934) E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-)|
          Length = 1000

 Score =  105 bits (261), Expect = 2e-22
 Identities = 52/103 (50%), Positives = 70/103 (67%)
 Frame = -3

Query: 661  SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKA 482
            +GYS    VIQWFW+ V     E + R LQFVTGTS+VP+ GF+ L G +GPQ F + + 
Sbjct: 896  NGYSANHQVIQWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQ- 954

Query: 481  YGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            +G+   LP AHTCFN+LDLP Y S ++L ++L +AI E  +GF
Sbjct: 955  WGTPEKLPRAHTCFNRLDLPPYESFEELWDKLQMAI-ENTQGF 996

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>SMUF1_DROME (Q9V853) E3 ubiquitin-protein ligase Smurf1 (EC 6.3.2.-) (Smad|
            ubiquitination regulatory factor 1 homolog) (DSmurf)
            (Lethal with a checkpoint kinase protein)
          Length = 1061

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 47/93 (50%), Positives = 65/93 (69%), Gaps = 4/93 (4%)
 Frame = -3

Query: 634  IQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGIS---GPQRFQIH-KAYGSTN 467
            + WFW++V+ +S E +AR LQFVTG+S+VPL+GF ALQG +   GP+ F IH  A   T 
Sbjct: 962  VLWFWQVVESYSSEMRARLLQFVTGSSRVPLQGFRALQGSTGAVGPRLFTIHLTADVPTQ 1021

Query: 466  HLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 368
            +LP AHTCFN++DLP Y +   L ++L  A+ E
Sbjct: 1022 NLPKAHTCFNRIDLPPYETYQLLCDKLTQAVEE 1054

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>UBE3A_HUMAN (Q05086) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP|
            ubiquitin-protein ligase) (Oncogenic protein-associated
            protein E6-AP) (Human papillomavirus E6-associated
            protein) (NY-REN-54 antigen)
          Length = 875

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 51/103 (49%), Positives = 65/103 (63%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GY+  S +I+ FWEIV  F+ E K  FLQF TGT + P+ G   L+ I       I K  
Sbjct: 779  GYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMI-------IAKNG 831

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              T  LP++HTCFN L LPEY+SK++L+ERLL AI  A +GFG
Sbjct: 832  PDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYA-KGFG 873

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>UBE3A_MOUSE (O08759) Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic|
            protein-associated protein E6-AP)
          Length = 885

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 50/103 (48%), Positives = 62/103 (60%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GY+  S VI+ FWEIV  F+ E K  FL F TGT + P+ G   L+ I       I K  
Sbjct: 789  GYTRESVVIREFWEIVHSFTDEQKRLFLLFTTGTDRAPVGGLGKLKMI-------IAKNG 841

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
              T  LP++HTCFN L LPEY+SK++L  RLL AI  A +GFG
Sbjct: 842  PDTERLPTSHTCFNVLLLPEYSSKEKLNVRLLKAITYA-KGFG 883

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>K0317_MOUSE (Q8CHG5) Protein KIAA0317|
          Length = 823

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 46/96 (47%), Positives = 62/96 (64%)
 Frame = -3

Query: 637  VIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLP 458
            V++WFW +V   ++E+ AR LQF TG+S++P  GF+AL        FQI  A  + + LP
Sbjct: 732  VMRWFWAVVSSLTQEELARLLQFTTGSSQLPPGGFAALC-----PSFQIIAA-PTHSTLP 785

Query: 457  SAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
            +AHTCFNQL LP Y S +++   L LAI E  EGFG
Sbjct: 786  TAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFG 821

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>K0317_HUMAN (O15033) Protein KIAA0317|
          Length = 823

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 46/96 (47%), Positives = 62/96 (64%)
 Frame = -3

Query: 637  VIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLP 458
            V++WFW +V   ++E+ AR LQF TG+S++P  GF+AL        FQI  A  + + LP
Sbjct: 732  VMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALC-----PSFQIIAA-PTHSTLP 785

Query: 457  SAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
            +AHTCFNQL LP Y S +++   L LAI E  EGFG
Sbjct: 786  TAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFG 821

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>HUL4_ASHGO (Q757T0) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 839

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 38/104 (36%), Positives = 62/104 (59%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            G+   SPV+QWFWEI+       + + L FVTG+ +VP  G + +        F+I +  
Sbjct: 743  GFDDNSPVVQWFWEILSEMEYPQQRKLLHFVTGSDRVPATGVTTIP-------FRISRIR 795

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 347
               + LP +HTCFN++ L EY  K+ L+ +L++A+ E ++G+GF
Sbjct: 796  SGADRLPLSHTCFNEICLHEYKDKETLRNKLIIALEE-SQGYGF 838

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>UBE3C_HUMAN (Q15386) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 44/102 (43%), Positives = 57/102 (55%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GYS   PVI+ FW +V+GF+ E+K + L+FVT  S+ PL GF  L        F IH   
Sbjct: 985  GYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELY-----PAFCIHNGG 1039

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
                 LP+A TC N L LPE+  +  L+ +LL AI E   GF
Sbjct: 1040 SDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAI-ECAAGF 1080

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>UBE3C_MOUSE (Q80U95) Ubiquitin-protein ligase E3C (EC 6.3.2.-)|
          Length = 1083

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 44/102 (43%), Positives = 57/102 (55%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GYS   PVI+ FW +V+GF+ E+K + L+FVT  S+ PL GF  L        F IH   
Sbjct: 985  GYSADHPVIKIFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELY-----PAFCIHNGG 1039

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
                 LP+A TC N L LPE+  +  L+ +LL AI E   GF
Sbjct: 1040 SDLERLPTASTCMNLLKLPEFYDEALLRSKLLYAI-ECAAGF 1080

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>HERC3_HUMAN (Q15034) HECT domain and RCC1-like domain protein 3|
          Length = 1050

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 42/105 (40%), Positives = 60/105 (57%), Gaps = 1/105 (0%)
 Frame = -3

Query: 664  YSG-YSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIH 488
            Y G YS   P ++ FWE    F  E K +FL F+TG+ ++P+ G ++LQ +       I 
Sbjct: 951  YKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIV-------IQ 1003

Query: 487  KAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
                   +LP AHTC+N LDLP+Y+SK+ L  RL  A+ +  EGF
Sbjct: 1004 STASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQAL-DNYEGF 1047

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>HUL5_YEAST (P53119) Probable ubiquitin-protein ligase HUL5 (EC 6.3.2.-)|
          Length = 910

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 41/98 (41%), Positives = 54/98 (55%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHK 485
            Y GY      I  FWE++  F  E+K  FL+FVT   + PL+GF AL       +F I  
Sbjct: 810  YGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALD-----PKFGIRN 864

Query: 484  AYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 371
            A      LP+A TC N L LP+Y +K  L+E+LL AI+
Sbjct: 865  AGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAIN 902

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>HUL4_YEAST (P40985) Probable ubiquitin-protein ligase HUL4 (EC 6.3.2.-) (HECT|
            ubiquitin ligase 4)
          Length = 892

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 40/104 (38%), Positives = 65/104 (62%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            G+S  S  + WFWEI++ +    + + LQFVT + ++P  G S +     P +  +  ++
Sbjct: 795  GFSDDSRAVCWFWEIIESWDYPLQKKLLQFVTASDRIPATGISTI-----PFKISLLGSH 849

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFGF 347
             S + LP AHTCFN++ L  Y+SK +L+ +LL AI+E +EG+GF
Sbjct: 850  DS-DDLPLAHTCFNEICLWNYSSKKKLELKLLWAINE-SEGYGF 891

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>UFD4_YEAST (P33202) Ubiquitin fusion degradation protein 4 (UB fusion protein 4)|
          Length = 1483

 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 43/107 (40%), Positives = 60/107 (56%), Gaps = 5/107 (4%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQI---H 488
            GY++ S +I  F  I+  F K ++  FLQF+TG+ K+P+ GF +L       +F +   H
Sbjct: 1379 GYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSLN-----PKFTVVLKH 1433

Query: 487  KAYGST--NHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
               G T   +LPS  TC N L LP+YTSKD ++ RL  AI E    F
Sbjct: 1434 AEDGLTADEYLPSVMTCANYLKLPKYTSKDIMRSRLCQAIEEGAGAF 1480

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>TRIPC_HUMAN (Q14669) Thyroid receptor-interacting protein 12 (TRIP12)|
          Length = 1992

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 39/106 (36%), Positives = 62/106 (58%), Gaps = 4/106 (3%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GY+  S  +++ +EI+  F  E +  FLQFVTG+ ++P+ GF +L     P    + K +
Sbjct: 1888 GYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSL----NPPLTIVRKTF 1943

Query: 478  GSTNH----LPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
             ST +    LPS  TC N L LP+Y+S + ++E+LL+A  E  + F
Sbjct: 1944 ESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGQQSF 1989

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>HERC2_HUMAN (O95714) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4834

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 3/101 (2%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGFSALQGISGPQRFQI 491
            Y G   ++ +IQWFWE+++ FS  +++ FL+FV G +++P  +  F     +      Q+
Sbjct: 4691 YKGIEPSASLIQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFV-----IQV 4745

Query: 490  HKAYGSTNH-LPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 371
               Y   +H LP ++TCF  L LP Y+ K  L+E+L  AIH
Sbjct: 4746 LDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIH 4786

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>HERC2_MOUSE (Q4U2R1) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4836

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 35/101 (34%), Positives = 58/101 (57%), Gaps = 3/101 (2%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGFSALQGISGPQRFQI 491
            Y G   ++ ++QWFWE+++ FS  +++ FL+FV G +++P  +  F     +      Q+
Sbjct: 4693 YKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFV-----IQV 4747

Query: 490  HKAYGSTNH-LPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 371
               Y   +H LP ++TCF  L LP Y+ K  L+E+L  AIH
Sbjct: 4748 LDKYNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIH 4788

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>YDE1_SCHPO (Q10435) Probable ubiquitin fusion degradation protein C12B10.01c|
          Length = 1647

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 38/102 (37%), Positives = 55/102 (53%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GY++ SP IQ    ++   + +++  FLQF+TG+ K+P+ GF+ L       R      Y
Sbjct: 1543 GYTMESPTIQRLLTLMSQMNFQEQRDFLQFITGSRKLPIGGFAGLNPPLTVVRRLNEPPY 1602

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
               ++LPS  TC N L LPEY+S + L  RL  AI E    F
Sbjct: 1603 VPDDYLPSVMTCVNYLKLPEYSSSEVLGSRLSKAILEGQGSF 1644

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>HERC2_DROME (Q9VR91) HECT domain and RCC1-like domain-containing protein 2|
          Length = 4912

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 31/100 (31%), Positives = 57/100 (57%), Gaps = 2/100 (2%)
 Frame = -3

Query: 664  YSGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVP--LEGFSALQGISGPQRFQI 491
            Y G+  +S ++ WFWE+++ F+ ++++ FL+FV G +++P  +  F     +      Q+
Sbjct: 4780 YKGFDPSSALVTWFWEVMEEFTNQERSLFLRFVWGRTRLPRTIADFRGRDFV-----LQV 4834

Query: 490  HKAYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIH 371
             +     + LP ++TCF  L +P Y+ K  L E+L  AIH
Sbjct: 4835 LEKNPPDHFLPESYTCFFLLKMPRYSCKAVLLEKLKYAIH 4874

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>HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing|
            protein 1) (E3 ligase for inhibin receptor) (EULIR)
          Length = 2612

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 35/97 (36%), Positives = 53/97 (54%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GY+  SP    F  ++ G S +++  FLQF TG S +P  G + L     P+   + K  
Sbjct: 2514 GYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLH----PRLTVVRKVD 2569

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHE 368
             +    PS +TC + L LPEY+S++ ++ERLL A  E
Sbjct: 2570 ATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATME 2606

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>HYD_DROME (P51592) Ubiquitin--protein ligase hyd (EC 6.3.2.-) (Protein|
            hyperplastic discs)
          Length = 2885

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 34/95 (35%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
 Frame = -3

Query: 631  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGISGPQRFQIHKAYGSTNHLP 458
            +WFW IV+  +  ++   + F TG+  +P   EGF  L  ++      I  A  S  HLP
Sbjct: 2798 KWFWSIVEKMNIMERQDLVYFWTGSPALPASEEGFQPLPSVT------IRPADDS--HLP 2849

Query: 457  SAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            +A+TC ++L +P Y+SK  L+ ++L+AI   N GF
Sbjct: 2850 TANTCISRLYIPLYSSKSILRSKMLMAIKSKNFGF 2884

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>EDD1_RAT (Q62671) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog) (100 kDa protein) (Fragment)
          Length = 920

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
 Frame = -3

Query: 631  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHL 461
            +WFW IV+  S  ++   + F T +  +P   EGF  +  I+  P   Q         HL
Sbjct: 833  RWFWSIVERMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ---------HL 883

Query: 460  PSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            P+A+TC ++L +P Y+SK  L+++LLLAI   N GF
Sbjct: 884  PTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGF 919

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>EDD1_MOUSE (Q80TP3) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog)
          Length = 2792

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
 Frame = -3

Query: 631  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHL 461
            +WFW IV+  S  ++   + F T +  +P   EGF  +  I+  P   Q         HL
Sbjct: 2705 RWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ---------HL 2755

Query: 460  PSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            P+A+TC ++L +P Y+SK  L+++LLLAI   N GF
Sbjct: 2756 PTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGF 2791

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>EDD1_HUMAN (O95071) Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic|
            discs protein homolog) (hHYD) (Progestin-induced protein)
          Length = 2799

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
 Frame = -3

Query: 631  QWFWEIVQGFSKEDKARFLQFVTGTSKVPL--EGFSALQGIS-GPQRFQIHKAYGSTNHL 461
            +WFW IV+  S  ++   + F T +  +P   EGF  +  I+  P   Q         HL
Sbjct: 2712 RWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQ---------HL 2762

Query: 460  PSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGF 353
            P+A+TC ++L +P Y+SK  L+++LLLAI   N GF
Sbjct: 2763 PTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGF 2798

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>HERC5_HUMAN (Q9UII4) HECT domain and RCC1-like domain-containing protein 5|
            (Cyclin-E-binding protein 1)
          Length = 1024

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 31/103 (30%), Positives = 58/103 (56%)
 Frame = -3

Query: 658  GYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAY 479
            GY+ + P I  FW+     + E+K +FL F+TGT ++ ++  + ++       F   +++
Sbjct: 929  GYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMK-----ITFCCPESW 983

Query: 478  GSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEANEGFG 350
               + +  A TCF+ L LP+Y++ + ++E L  AI+  N GFG
Sbjct: 984  NERDPI-RALTCFSVLFLPKYSTMETVEEALQEAINN-NRGFG 1024

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>MUT7_CAEEL (P34607) Probable exonuclease mut-7 (EC 3.1.-.-)|
          Length = 910

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
 Frame = +2

Query: 428 VQLVKASMSRGKMVGAAVRLVYLEP--LWPRYSLKRTETLQRYL 553
           V ++KA   RGK  G ++ + YLE   +W + S + TE  Q+YL
Sbjct: 72  VDMMKAMPDRGKTSGQSLAVWYLEDFGVWLKESGQETELRQKYL 115

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>FBN3_HUMAN (Q75N90) Fibrillin-3 precursor|
          Length = 2809

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 19/53 (35%), Positives = 24/53 (45%)
 Frame = +1

Query: 82   GVCLNSHSSLHILCSNLFALIMEDLSHFPTNMENLLVVTKADASCCQLVGSSR 240
            G CLN+  S H LC + F L  +  +   TN    L  T    +C  L GS R
Sbjct: 1901 GHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953

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>GLMM_PHOLL (Q7MYY3) Phosphoglucosamine mutase (EC 5.4.2.10)|
          Length = 445

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 6/50 (12%)
 Frame = +1

Query: 73  QIVGVCLNSHSSLHILCSNLFAL------IMEDLSHFPTNMENLLVVTKA 204
           QI+   + +H SLH LCS +  L      +    SH P   EN++ +TK+
Sbjct: 347 QILSAMVRNHMSLHDLCSGMKLLPQVLVNVRFSGSHDPLKSENVINITKS 396

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>CENB2_HUMAN (Q15057) Centaurin-beta 2 (Cnt-b2)|
          Length = 778

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 22/75 (29%), Positives = 33/75 (44%)
 Frame = -3

Query: 613 VQGFSKEDKARFLQFVTGTSKVPLEGFSALQGISGPQRFQIHKAYGSTNHLPSAHTCFNQ 434
           +Q F KED  +F        KV  E  +AL   +  QR + H+   +TN L +   CF  
Sbjct: 109 LQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRH 168

Query: 433 LDLPEYTSKDQLQER 389
           + L      + LQ +
Sbjct: 169 IALDYVLQINVLQSK 183


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,462,715
Number of Sequences: 219361
Number of extensions: 2440103
Number of successful extensions: 5911
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 5657
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5866
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6541540170
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

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full-length cDNA and EST

Clone Information

BLAST Search Result