ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal39k05 |
|---|---|
| Clone Library Name | barley_pub |
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 79.7 bits (195), Expect = 8e-15 Identities = 52/134 (38%), Positives = 83/134 (61%), Gaps = 4/134 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLAKL + +T TA RGT+G+IAPE S G S K+DV+ +G+++LE+++G+R Sbjct: 436 GLAKLMDYKDTHVT-TAVRGTIGHIAPEYLST--GKSSEKTDVFGYGVMLLELITGQRAF 492 Query: 504 DPS-VEYQDEVYLPEWVYEGVISGHEWELTSEMTAE---EKEKMRQLTIVALWCIQWNPK 337 D + + D+V L +WV +G++ + E ++ + + E++ QL VAL C Q +P Sbjct: 493 DLARLANDDDVMLLDWV-KGLLKEKKLEALVDVDLQGNYKDEEVEQLIQVALLCTQSSPM 551 Query: 336 NRPSMTKVVNMLTG 295 RP M++VV ML G Sbjct: 552 ERPKMSEVVRMLEG 565
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 66.6 bits (161), Expect = 7e-11 Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 2/141 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GL+ L D GT+GY+ PE Y ++ ++ KSDVYSFG+++LE++SGR+ Sbjct: 654 GLSILGPADSGTPLSELPAGTLGYLDPEYYRLHY--LTTKSDVYSFGVVLLEILSGRKAI 711 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTA--EEKEKMRQLTIVALWCIQWNPKNR 331 D E E + EW + +G + + + + + E ++++ VA C++ K+R Sbjct: 712 DMQFE---EGNIVEWAVPLIKAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDR 768 Query: 330 PSMTKVVNMLTGRLQNLQIPP 268 PSM KV L L L P Sbjct: 769 PSMDKVTTALEHALALLMGSP 789
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 64.3 bits (155), Expect = 3e-10 Identities = 42/116 (36%), Positives = 70/116 (60%), Gaps = 2/116 (1%) Frame = -3 Query: 642 LTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLP 466 ++ G+ GYIAPE VY+ V+ KSD+YSFG+++LE+V+G++ +D + +D + Sbjct: 855 MSGIAGSCGYIAPEYVYTLR---VNEKSDIYSFGVVLLELVTGKQPTDSELGDKD---MA 908 Query: 465 EWVYEGVIS-GHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 +WV + G E + ++ + KE++ ++ + L C P NRPSM KVV ML Sbjct: 909 KWVCTALDKCGLEPVIDPKLDLKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIML 964
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 63.5 bits (153), Expect = 6e-10 Identities = 43/152 (28%), Positives = 81/152 (53%), Gaps = 11/152 (7%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+A++ RD++ GT GY++PE +G S KSDV+SFG++VLE+VSG++N Sbjct: 673 GMARIFERDETEANTMKVVGTYGYMSPEYAM--YGIFSEKSDVFSFGVIVLEIVSGKKNR 730 Query: 504 D-PSVEYQDEVYLPEW----------VYEGVISGHEWELTSEMTAEEKEKMRQLTIVALW 358 +++Y++++ W + + VI L+S+ + + +++ + + L Sbjct: 731 GFYNLDYENDLLSYVWSRWKEGRALEIVDPVIVD---SLSSQPSIFQPQEVLKCIQIGLL 787 Query: 357 CIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 262 C+Q ++RP+M+ VV M + P P Sbjct: 788 CVQELAEHRPAMSSVVWMFGSEATEIPQPKPP 819
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 62.0 bits (149), Expect = 2e-09 Identities = 40/130 (30%), Positives = 68/130 (52%), Gaps = 2/130 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L + +S ++ T GT GYI PE Y ++ + K DVYSFG+++LE+V+G+ + Sbjct: 1063 GLARLISACESHVS-TVIAGTFGYIPPE-YGQSARATT-KGDVYSFGVILLELVTGKEPT 1119 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTI--VALWCIQWNPKNR 331 P + + L W + + G ++ + K QL + +A+ C+ P R Sbjct: 1120 GPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKR 1179 Query: 330 PSMTKVVNML 301 P+M V+ L Sbjct: 1180 PNMLDVLKAL 1189
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 61.6 bits (148), Expect = 2e-09 Identities = 45/145 (31%), Positives = 77/145 (53%), Gaps = 6/145 (4%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLAKL D+ T GT GY APE + G + KSDV++FG+++LE+++G + Sbjct: 238 GLAKLGPADEKSHVTTRIMGTYGYAAPEYMAT--GHLYVKSDVFAFGVVLLEIMTGL-TA 294 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWE------LTSEMTAEEKEKMRQLTIVALWCIQWN 343 + + + L +W+ + + H + + + T + +M ++T L CI+ + Sbjct: 295 HNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARIT---LSCIEPD 351 Query: 342 PKNRPSMTKVVNMLTGRLQNLQIPP 268 PKNRP M +VV +L +Q L + P Sbjct: 352 PKNRPHMKEVVEVLE-HIQGLNVVP 375
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 58.5 bits (140), Expect = 2e-08 Identities = 43/130 (33%), Positives = 68/130 (52%), Gaps = 2/130 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L + +T T GT+GYI PE + +YK DVYSFG+++LE+++GRR Sbjct: 889 GLARLILPYDTHVT-TDLVGTLGYIPPEYGQASVA--TYKGDVYSFGVVLLELLTGRRPM 945 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEM--TAEEKEKMRQLTIVALWCIQWNPKNR 331 D + + L WV + E E+ + E+M + +A C+ NPK R Sbjct: 946 D-VCKPRGSRDLISWVLQMKTEKRESEIFDPFIYDKDHAEEMLLVLEIACRCLGENPKTR 1004 Query: 330 PSMTKVVNML 301 P+ ++V+ L Sbjct: 1005 PTTQQLVSWL 1014
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 58.2 bits (139), Expect = 2e-08 Identities = 40/138 (28%), Positives = 69/138 (50%), Gaps = 5/138 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GL +L + I T GT GY+APE G V+ K DVYSFG++++E+++GR++ Sbjct: 737 GLVRLAPEGKGSIE-TRIAGTFGYLAPEYAVT--GRVTTKVDVYSFGVILMELITGRKSL 793 Query: 504 DPSVEYQDEVYLPEWVYEGVISGH-----EWELTSEMTAEEKEKMRQLTIVALWCIQWNP 340 D S + ++ ++L W I+ + T ++ E + + +A C P Sbjct: 794 DES-QPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREP 852 Query: 339 KNRPSMTKVVNMLTGRLQ 286 RP M VN+L+ ++ Sbjct: 853 YQRPDMGHAVNILSSLVE 870
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 57.0 bits (136), Expect = 5e-08 Identities = 37/116 (31%), Positives = 63/116 (54%), Gaps = 3/116 (2%) Frame = -3 Query: 639 TAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEW 460 T GT GY APE + G +S KSDVYSFG+++LE++SGRR D + + E L +W Sbjct: 238 TRVMGTQGYAAPEYLAT--GHLSVKSDVYSFGVVLLELLSGRRAIDKN-QPVGEHNLVDW 294 Query: 459 VYEGVISGHEWELTSEMTAEEKEKMR---QLTIVALWCIQWNPKNRPSMTKVVNML 301 + + + + + + ++ ++AL CI + K+RP+M ++V + Sbjct: 295 ARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTM 350
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 56.6 bits (135), Expect = 7e-08 Identities = 44/159 (27%), Positives = 75/159 (47%), Gaps = 3/159 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLAK+ T GT GY AP+ Y+ G +++KSD+YSFG+++LE+++GR+ Sbjct: 250 GLAKVGPSGDKTHVSTRVMGTYGYCAPD-YAMT-GQLTFKSDIYSFGVVLLELITGRKAI 307 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMR---QLTIVALWCIQWNPKN 334 D + +D+ L W + + + + +R Q ++ C+Q P Sbjct: 308 DNTKTRKDQ-NLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQALAISAMCVQEQPTM 366 Query: 333 RPSMTKVVNMLTGRLQNLQIPPKPFVSSENHPRA*KHRE 217 RP ++ VV L + P P SS +P + R+ Sbjct: 367 RPVVSDVVLALNFLASSKYDPNSPSSSSGKNPSFHRDRD 405
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 56.6 bits (135), Expect = 7e-08 Identities = 46/153 (30%), Positives = 74/153 (48%), Gaps = 13/153 (8%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLAK + +++ G+ GYIAPE Y+ V KSDVYSFG+++LE+++G++ Sbjct: 837 GLAKFLVDGAASECMSSIAGSYGYIAPE-YAYTLK-VDEKSDVYSFGVVLLELIAGKK-- 892 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTS-------------EMTAEEKEKMRQLTIVA 364 P E+ + V + WV E E+T +T + + +A Sbjct: 893 -PVGEFGEGVDIVRWV-----RNTEEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIA 946 Query: 363 LWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPK 265 + C++ RP+M +VV+MLT PPK Sbjct: 947 MMCVEEEAAARPTMREVVHMLTN-------PPK 972
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 56.2 bits (134), Expect = 9e-08 Identities = 40/116 (34%), Positives = 63/116 (54%), Gaps = 3/116 (2%) Frame = -3 Query: 639 TAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEW 460 T GT GY APE + G ++ KSDVYSFG+++LE++SGRR D + E L EW Sbjct: 238 TRVMGTHGYAAPEYLAT--GHLTTKSDVYSFGVVLLELLSGRRAVDKN-RPSGERNLVEW 294 Query: 459 VYEGVISGHEWELTSEMTAEEKEKMRQLTIVA---LWCIQWNPKNRPSMTKVVNML 301 +++ + + +++ M + VA L C+ K RP+M++VV+ L Sbjct: 295 AKPYLVNKRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHL 350
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 55.5 bits (132), Expect = 2e-07 Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 3/136 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+A+L + + ++++ GT GY+ PE Y ++F + K DVYS+G+++LE++SG++ Sbjct: 1005 GMARLVSALDTHLSVSTLAGTPGYVPPEYY-QSFRCTA-KGDVYSYGVILLELLSGKKPI 1062 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKE---KMRQLTIVALWCIQWNPKN 334 DP E+ ++ L W + E+ +K ++ +A C+ P Sbjct: 1063 DPE-EFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFK 1121 Query: 333 RPSMTKVVNMLTGRLQ 286 RP+M +V+ M +Q Sbjct: 1122 RPTMIQVMTMFKELVQ 1137
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 55.5 bits (132), Expect = 2e-07 Identities = 42/131 (32%), Positives = 67/131 (51%), Gaps = 3/131 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLAK T GT GY APE + G ++ KSDVYS+G+++LE++SGRR Sbjct: 224 GLAKDGPTGDKSHVSTRIMGTYGYAAPEYLAT--GHLTTKSDVYSYGVVLLEVLSGRRAV 281 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQ---LTIVALWCIQWNPKN 334 D + E L EW + + + + +++ M + + +AL C+ + K Sbjct: 282 DKN-RPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKL 340 Query: 333 RPSMTKVVNML 301 RP+M +VV+ L Sbjct: 341 RPNMNEVVSHL 351
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 55.5 bits (132), Expect = 2e-07 Identities = 43/131 (32%), Positives = 75/131 (57%), Gaps = 4/131 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+A+L + + ++++ GT GY+ PE Y ++F S K DVYS+G+++LE+++G+R + Sbjct: 1029 GMARLMSAMDTHLSVSTLAGTPGYVPPEYY-QSFR-CSTKGDVYSYGVVLLELLTGKRPT 1086 Query: 504 DPSVEYQDEVYLPEWVYE----GVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPK 337 D S ++ D L WV + + + EL E A E E ++ L VA+ C+ Sbjct: 1087 D-SPDFGDN-NLVGWVKQHAKLRISDVFDPELMKEDPALEIELLQHLK-VAVACLDDRAW 1143 Query: 336 NRPSMTKVVNM 304 RP+M +V+ M Sbjct: 1144 RRPTMVQVMAM 1154
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 55.1 bits (131), Expect = 2e-07 Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 8/137 (5%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGV-SYKSDVYSFGMLVLEMVSGRRN 508 G+AKL + + I +GT+GY+APE F V S +SDVYS+G+++LE+++ ++ Sbjct: 962 GIAKLLDQSATSIPSNTVQGTIGYMAPE---NAFTTVKSRESDVYSYGVVLLELITRKKA 1018 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWE-------LTSEMTAEEKEKMRQLTIVALWCIQ 349 DPS + E + WV E + L + + E++ + +AL C + Sbjct: 1019 LDPS--FNGETDIVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAE 1076 Query: 348 WNPKNRPSMTKVVNMLT 298 RP+M VV LT Sbjct: 1077 KEVDKRPTMRDVVKQLT 1093
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 54.3 bits (129), Expect = 3e-07 Identities = 45/146 (30%), Positives = 71/146 (48%), Gaps = 18/146 (12%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+A+L + + ++++ GT GY+ PE Y ++F + K DVYS G+++LE++SG+R + Sbjct: 986 GMARLISALDTHLSVSTLAGTPGYVPPEYY-QSFRCTA-KGDVYSIGVVMLEILSGKRPT 1043 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEE------------------KEKMRQ 379 D E + L W G E+ E +E KE +R Sbjct: 1044 DK--EEFGDTNLVGWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRY 1101 Query: 378 LTIVALWCIQWNPKNRPSMTKVVNML 301 L I AL C+ P RP+M +VV L Sbjct: 1102 LEI-ALRCVDDFPSKRPNMLQVVASL 1126
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 53.1 bits (126), Expect = 8e-07 Identities = 39/130 (30%), Positives = 71/130 (54%), Gaps = 2/130 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L + ++ ++ T GT+GYI PE + +YK DVYSFG+++LE+++ +R Sbjct: 880 GLARLMSPYETHVS-TDLVGTLGYIPPEYGQASVA--TYKGDVYSFGVVLLELLTDKRPV 936 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEM--TAEEKEKMRQLTIVALWCIQWNPKNR 331 D + + L WV + E+ + + E ++M ++ +A C+ NPK R Sbjct: 937 D-MCKPKGCRDLISWVVKMKHESRASEVFDPLIYSKENDKEMFRVLEIACLCLSENPKQR 995 Query: 330 PSMTKVVNML 301 P+ ++V+ L Sbjct: 996 PTTQQLVSWL 1005
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 52.8 bits (125), Expect = 1e-06 Identities = 42/137 (30%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G +K ++ RGT GY+ PE Y +S KSDV+SFG+++LE+VSGR Sbjct: 741 GFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGREPL 798 Query: 504 D---PSVEYQDEVYLPEWVYEGVISGHEWELTSE--MTAEEKEKMRQLTIVALWCIQWNP 340 + P VE+ L EW + + E+ E + ++ VAL C++ Sbjct: 799 NIKRPRVEWS----LVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYS 854 Query: 339 KNRPSMTKVVNMLTGRL 289 RP M +V L L Sbjct: 855 TYRPCMVDIVRELEDAL 871
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 52.8 bits (125), Expect = 1e-06 Identities = 43/131 (32%), Positives = 76/131 (58%), Gaps = 4/131 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+A+L + + ++++ GT GY+ PE Y ++F S K DVYS+G+++LE+++G++ + Sbjct: 1034 GMARLMSAMDTHLSVSTLAGTPGYVPPEYY-QSFR-CSTKGDVYSYGVVLLELLTGKQPT 1091 Query: 504 DPSVEYQDEVYLPEWV---YEGVISG-HEWELTSEMTAEEKEKMRQLTIVALWCIQWNPK 337 D S ++ D L WV +G I+ + EL E + E E ++ L VA C+ Sbjct: 1092 D-SADFGDN-NLVGWVKLHAKGKITDVFDRELLKEDASIEIELLQHLK-VACACLDDRHW 1148 Query: 336 NRPSMTKVVNM 304 RP+M +V+ M Sbjct: 1149 KRPTMIQVMAM 1159
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 52.8 bits (125), Expect = 1e-06 Identities = 43/131 (32%), Positives = 76/131 (58%), Gaps = 4/131 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+A+L + + ++++ GT GY+ PE Y ++F S K DVYS+G+++LE+++G++ + Sbjct: 1034 GMARLMSAMDTHLSVSTLAGTPGYVPPEYY-QSFR-CSTKGDVYSYGVVLLELLTGKQPT 1091 Query: 504 DPSVEYQDEVYLPEWV---YEGVISG-HEWELTSEMTAEEKEKMRQLTIVALWCIQWNPK 337 D S ++ D L WV +G I+ + EL E + E E ++ L VA C+ Sbjct: 1092 D-SADFGDN-NLVGWVKLHAKGKITDVFDRELLKEDASIEIELLQHLK-VACACLDDRHW 1148 Query: 336 NRPSMTKVVNM 304 RP+M +V+ M Sbjct: 1149 KRPTMIQVMAM 1159
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 52.8 bits (125), Expect = 1e-06 Identities = 35/130 (26%), Positives = 69/130 (53%), Gaps = 3/130 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+A+L + + ++++ GT GY+ PE Y ++F + K DVYS+G+++LE++SG++ Sbjct: 1007 GMARLVSALDTHLSVSTLAGTPGYVPPEYY-QSFRCTA-KGDVYSYGVILLELLSGKKPI 1064 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKE---KMRQLTIVALWCIQWNPKN 334 DP E+ ++ L W + E+ +K ++ +A C+ P Sbjct: 1065 DPG-EFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFK 1123 Query: 333 RPSMTKVVNM 304 RP+M +++ M Sbjct: 1124 RPTMIQLMAM 1133
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G +K ++ RGT GY+ PE Y +S KSDV+SFG+++LE+VSGR Sbjct: 742 GFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGREPL 799 Query: 504 D---PSVEYQDEVYLPEWVYEGVISGHEWELTSE--MTAEEKEKMRQLTIVALWCIQWNP 340 + P +E+ L EW + + E+ E + ++ VAL C++ Sbjct: 800 NIKRPRIEWS----LVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYS 855 Query: 339 KNRPSMTKVVNMLTGRL 289 RP M +V L L Sbjct: 856 TYRPCMVDIVRELEDAL 872
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 52.4 bits (124), Expect = 1e-06 Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 3/132 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLAKL T GT GY APE Y+ G ++ KSDVYSFG++ LE+++GR+ Sbjct: 233 GLAKLGPTGDKSHVSTRVMGTYGYCAPE-YAMT-GQLTVKSDVYSFGVVFLELITGRKAI 290 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMR---QLTIVALWCIQWNPKN 334 D + + E L W ++ ++ + + R Q VA CIQ Sbjct: 291 DSEMPH-GEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRALYQALAVASMCIQEQAAT 349 Query: 333 RPSMTKVVNMLT 298 RP + VV L+ Sbjct: 350 RPLIADVVTALS 361
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/130 (30%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+ AR + + GT Y+APE G ++ KSD+YSFG+++LE+++G Sbjct: 331 GLARASARLAQTVMTSRIVGTTAYMAPEALR---GEITPKSDIYSFGVVLLELITGLAAV 387 Query: 504 DPSVEYQDEVYLPEWV--YEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNR 331 D + E Q + + E + E I + E S+ E M A C+ R Sbjct: 388 DENREPQLLLDIKEEIEDEEKTIEDYTDEKMSDADPASVEAMYS---AASQCLHEKKNRR 444 Query: 330 PSMTKVVNML 301 P + KV +L Sbjct: 445 PDIAKVQQLL 454
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 49.7 bits (117), Expect = 8e-06 Identities = 47/138 (34%), Positives = 72/138 (52%), Gaps = 10/138 (7%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GL KL R S ++ RGT+GYIAPE S ++ K DVYS+G+++LE+++G R S Sbjct: 678 GLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSL--PITAKVDVYSYGVVLLELLTGTRVS 735 Query: 504 DPSVEYQDEVY--LPEWV--YEGVISGHE--W---ELTSEMTAE-EKEKMRQLTIVALWC 355 + V DEV+ L + V + G E W L S++ + R L +A+ C Sbjct: 736 E-LVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSC 794 Query: 354 IQWNPKNRPSMTKVVNML 301 ++ + RP+M V L Sbjct: 795 LEEDRSKRPTMEHAVQTL 812
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 47.8 bits (112), Expect = 3e-05 Identities = 33/128 (25%), Positives = 62/128 (48%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+ + + + GT Y+APE G ++ KSD+YSFG+++LE+++G Sbjct: 331 GLARASEKFAQTVMTSRIVGTTAYMAPEALR---GEITPKSDIYSFGVVLLEIITGLPAV 387 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 D E Q + + E + + + ++ + +M + + + VA C+ RP Sbjct: 388 DEHREPQLLLDIKEEIEDEEKTIEDY-IDKKMNDADSTSVEAMYSVASQCLHEKKNKRPD 446 Query: 324 MTKVVNML 301 + KV +L Sbjct: 447 IKKVQQLL 454
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 47.4 bits (111), Expect = 4e-05 Identities = 36/119 (30%), Positives = 62/119 (52%), Gaps = 4/119 (3%) Frame = -3 Query: 654 SIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEV 475 +++ + GT Y+ PE RNF +S DVYSFG+++LE+ +GR+ +D E + + Sbjct: 377 AVVEVNKVFGTKIYLPPEF--RNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKK 434 Query: 474 YLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVA----LWCIQWNPKNRPSMTKVV 310 L ++V + + EL + A K + + A L C +P++RPSM V+ Sbjct: 435 NLLDYVKQ-QWRQNRMELLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVL 492
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 2/103 (1%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT+GY+APE++ S SDVYSFG+L+ +++GR VE E P VYE Sbjct: 181 GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGR-----EVELPTE---PSLVYEA 232 Query: 447 VISGHEWELTSEM--TAEEKEKMRQLTIVALWCIQWNPKNRPS 325 V + +E+ E + L + C PK+RPS Sbjct: 233 VCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPS 275
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 47.0 bits (110), Expect = 5e-05 Identities = 34/129 (26%), Positives = 70/129 (54%), Gaps = 4/129 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GL++ + + S T G++GY+ PE YS ++ KSDVYS G+++LE+++G+ Sbjct: 717 GLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTR--QMNEKSDVYSLGVVLLEVITGQ--- 771 Query: 504 DPSV--EYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKE--KMRQLTIVALWCIQWNPK 337 P++ ++V++ + V + +G + + E + +++ +AL C + Sbjct: 772 -PAIASSKTEKVHISDHVRSILANGDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSA 830 Query: 336 NRPSMTKVV 310 RP+M++VV Sbjct: 831 QRPTMSQVV 839
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 44.3 bits (103), Expect = 4e-04 Identities = 38/137 (27%), Positives = 62/137 (45%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L RD + A+ + + APE + N S KSDV++FG+L+ E+ + + Sbjct: 512 GLARLM-RDDTYTAHAGAKFPIKWTAPEGLAYN--KFSTKSDVWAFGVLLWEIATYGMSP 568 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P+++ D VY + G+ E E + MRQ C QW+ +RP+ Sbjct: 569 YPAIDLTD-------VYHKLDKGYRMERPPGCPPEVYDLMRQ-------CWQWDATDRPT 614 Query: 324 MTKVVNMLTGRLQNLQI 274 + + L Q I Sbjct: 615 FKSIHHALEHMFQESSI 631
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 43.1 bits (100), Expect = 8e-04 Identities = 32/108 (29%), Positives = 60/108 (55%), Gaps = 1/108 (0%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFG-GVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYE 451 GT Y+APEV +R G G +D++S G +V+EMV+G+R P EY+ + +Y+ Sbjct: 1503 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKR---PWHEYEHNFQI---MYK 1556 Query: 450 GVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 V GH+ + ++ E K+ + C++ +PK R + +++++ Sbjct: 1557 -VGMGHKPPIPERLSPEGKDFLSH-------CLESDPKMRWTASQLLD 1596
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGT---MGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GL++L D T TA GT + + APE S + S KSDV++FG+L+ E+ + Sbjct: 332 GLSRLMTGD----TYTAHAGTKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYG 385 Query: 513 RNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKN 334 + P ++ VYE + + E + E MR C QWNP + Sbjct: 386 MSPYPGIDLSQ-------VYELLEKDYRMERPEGCPEKVYELMRA-------CWQWNPSD 431 Query: 333 RPSMTKV 313 RP+ ++ Sbjct: 432 RPAFAEI 438
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 41.6 bits (96), Expect = 0.002 Identities = 32/108 (29%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFG-GVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYE 451 GT Y+APEV +R G G +D++S G +V+EMV+G+R P EY+ + +Y+ Sbjct: 1493 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKR---PWHEYEHNFQI---MYK 1546 Query: 450 GVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 V GH+ + ++ E K + C++ +PK R + +++++ Sbjct: 1547 -VGMGHKPPIPERLSPEGKAFLSH-------CLESDPKIRWTASQLLD 1586
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGT---MGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GL++L D T TA G + + APE S + S KSDV++FG+L+ E+ + Sbjct: 269 GLSRLMTGD----TYTAHAGAKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYG 322 Query: 513 RNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKN 334 + P ++ VYE + + E + E MR C QWNP + Sbjct: 323 MSPYPGIDLSQ-------VYELLEKDYRMERPEGCPEKVYELMRA-------CWQWNPSD 368 Query: 333 RPSMTKV 313 RPS ++ Sbjct: 369 RPSFAEI 375
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGT---MGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GL++L D T TA G + + APE S + S KSDV++FG+L+ E+ + Sbjct: 383 GLSRLMTGD----TYTAHAGAKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYG 436 Query: 513 RNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKN 334 + P ++ VYE + + E + E MR C QWNP + Sbjct: 437 MSPYPGIDLSQ-------VYELLEKDYRMERPEGCPEKVYELMRA-------CWQWNPSD 482 Query: 333 RPSMTKV 313 RPS ++ Sbjct: 483 RPSFAEI 489
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGT---MGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GL++L D T TA G + + APE S + S KSDV++FG+L+ E+ + Sbjct: 383 GLSRLMTGD----TYTAHAGAKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYG 436 Query: 513 RNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKN 334 + P ++ VYE + + E + E MR C QWNP + Sbjct: 437 MSPYPGIDLSQ-------VYELLEKDYRMERPEGCPEKVYELMRA-------CWQWNPSD 482 Query: 333 RPSMTKV 313 RPS ++ Sbjct: 483 RPSFAEI 489
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 40.8 bits (94), Expect = 0.004 Identities = 39/156 (25%), Positives = 67/156 (42%), Gaps = 11/156 (7%) Frame = -3 Query: 639 TAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEW 460 T R + ++APE F KSDV+S+G+L+ E+++ + P++ +E Sbjct: 591 TNGRLPIKWMAPESLQEKF--YDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEE------ 642 Query: 459 VYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQ-- 286 +Y ++SG E ++ + MRQ C +N +RP T++V + LQ Sbjct: 643 LYTYLMSGQRMEKPAKCSMNIYILMRQ-------CWHFNADDRPPFTEIVEYMDKLLQTK 695 Query: 285 ---------NLQIPPKPFVSSENHPRA*KHRECCHY 205 NL PP S E ++ C+Y Sbjct: 696 EDYLDVDIANLDTPPS--TSDEEEDETDNLQKWCNY 729
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/117 (26%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Frame = -3 Query: 627 GTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYE 451 G++ ++APEV + S++SDVY+FG+++ E+++ P ++ + V Sbjct: 587 GSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLA---ECLPYGHISNKDQILFMVGR 643 Query: 450 GVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNL 280 G+ L +M+ + + L +A CI++ PK+RP ++NML L+ L Sbjct: 644 GL-------LRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTL 693
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 40.8 bits (94), Expect = 0.004 Identities = 37/132 (28%), Positives = 64/132 (48%), Gaps = 3/132 (2%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR--NSDPS-VEYQDE 478 I +T++ + PE Y R G +S K+DVYSFG++++E+++G R DP ++ +D Sbjct: 328 INMTSSSSKHLWYMPEEYIRQ-GKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRD- 385 Query: 477 VYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLT 298 L E + + + L ++ + +L +A C K RPSM +V+N L Sbjct: 386 -LLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLE 444 Query: 297 GRLQNLQIPPKP 262 +L P Sbjct: 445 STQASLYFAEDP 456
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 40.4 bits (93), Expect = 0.005 Identities = 19/40 (47%), Positives = 29/40 (72%) Frame = -3 Query: 630 RGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 +G++ ++APEV + G S K DV+S G +VLEM++GRR Sbjct: 993 QGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRR 1032
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 40.0 bits (92), Expect = 0.007 Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 2/103 (1%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT+ Y+APE+ N G S SDVYSFG+LV +++GR E D+ L + Sbjct: 184 GTLAYLAPELLD-NDGKASKASDVYSFGVLVWTVLAGR-----EAEVVDKTSL---IRGA 234 Query: 447 VISGHEWELTSEMTAEEKEK--MRQLTIVALWCIQWNPKNRPS 325 V + +E+ + E + L + C PK+RPS Sbjct: 235 VCNRQRRPPLTELPPDSPETPGLEGLKELMTHCWSSEPKDRPS 277
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 39.7 bits (91), Expect = 0.009 Identities = 31/125 (24%), Positives = 62/125 (49%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GL++L + + +T + G + Y+APEV+ + S KSDVYS+GM++ E+++ Sbjct: 1450 GLSRL--KKEQASQMTQSVGCIPYMAPEVFKGDSN--SEKSDVYSYGMVLFELLT----- 1500 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 S E Q ++ + + + + +++ KE + Q C NP +RP+ Sbjct: 1501 --SDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQ-------CWDSNPDSRPT 1551 Query: 324 MTKVV 310 +++ Sbjct: 1552 FKQII 1556
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 39.3 bits (90), Expect = 0.011 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 9/137 (6%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSY--KSDVYSFGMLVLE------ 529 G+A+ C R + + + GT G+ APEV G V Y ++DVYSFG+L+ + Sbjct: 2019 GIAQYCCR----MGIKTSEGTPGFRAPEVAR---GNVIYNQQADVYSFGLLLYDILTTGG 2071 Query: 528 -MVSGRRNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCI 352 +V G + + E + + LP+ V E W + ++ + C+ Sbjct: 2072 RIVEGLKFPNEFDELEIQGKLPDPVKE--YGCAPWPMVEKLIKQ--------------CL 2115 Query: 351 QWNPKNRPSMTKVVNML 301 + NP+ RP+ +V ++L Sbjct: 2116 KENPQERPTSAQVFDIL 2132
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 38.9 bits (89), Expect = 0.015 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 7/67 (10%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR---RNSDPSVEYQD----EVYL 469 GT Y+APEV SRN G +K+DV+S G+++ +++G R+S+ Y+ EV Sbjct: 173 GTPAYVAPEVISRN-GYDGFKADVWSCGVILFVLLAGYLPFRDSNLMELYKKIGKAEVKF 231 Query: 468 PEWVYEG 448 P W+ G Sbjct: 232 PNWLAPG 238
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 38.9 bits (89), Expect = 0.015 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 5/111 (4%) Frame = -3 Query: 618 GYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVIS 439 GY APE++ + +SDVY+FG+L+LE++ G++ + V LP V V+ Sbjct: 541 GYKAPELHKMK--KCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLE 598 Query: 438 G-----HEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 + E + + +E + +A+ C RPSM +VV L Sbjct: 599 ETTMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQL 649
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 38.1 bits (87), Expect = 0.025 Identities = 31/113 (27%), Positives = 59/113 (52%) Frame = -3 Query: 639 TAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEW 460 T +GT+ Y+APE + K DVYSFG+++ E+++ R+ +E + Y Sbjct: 164 TDMQGTLRYMAPEAIKHL--KYTAKCDVYSFGIMLWELMT-RQLPYSHLENPNSQYA--- 217 Query: 459 VYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 + + + SG + + + + ++ E ++QL C+ NP+ RPSM ++ L Sbjct: 218 IMKAISSGEKLPMEA-VRSDCPEGIKQLMEC---CMDINPEKRPSMKEIEKFL 266
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 38.1 bits (87), Expect = 0.025 Identities = 28/109 (25%), Positives = 56/109 (51%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT GY APE+ R K D++S+GM++ E++SG+R P++ + ++ + + + +G Sbjct: 1449 GTPGYQAPEIRPRIV--YDEKVDMFSYGMVLYELLSGQR---PALGHH-QLQIAKKLSKG 1502 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 + + E+ + R+L + + C P+ RP VV+ + Sbjct: 1503 I--------RPVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQM 1543
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 38.1 bits (87), Expect = 0.025 Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 3/126 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGT---MGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GL++L D T TA G + + APE S + S KSDV++FG+L+ E+ + Sbjct: 429 GLSRLMTGD----TYTAHAGAKFPIKWTAPE--SLAYNTFSIKSDVWAFGVLLWEIATYG 482 Query: 513 RNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKN 334 + P ++ VY+ + G+ E + E MR C +W+P + Sbjct: 483 MSPYPGIDLSQ-------VYDLLEKGYRMEQPEGCPPKVYELMRA-------CWKWSPAD 528 Query: 333 RPSMTK 316 RPS + Sbjct: 529 RPSFAE 534
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 38.1 bits (87), Expect = 0.025 Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 1/129 (0%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEM-VSGRRN 508 G+A+ DQ + + A+ + + PEV+ N+ S KSDV+SFG+L+ E+ GR Sbjct: 508 GMARYVLDDQ-YTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEIFTEGRMP 564 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 + + Y+ V V GH K + L V L C Q P+ RP Sbjct: 565 FEKNTNYE--------VVTMVTRGHRLH-------RPKLATKYLYEVMLRCWQERPEGRP 609 Query: 327 SMTKVVNML 301 S+ ++ + Sbjct: 610 SLEDLLRTI 618
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 38.1 bits (87), Expect = 0.025 Identities = 41/151 (27%), Positives = 63/151 (41%), Gaps = 5/151 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAAR-GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR-- 514 G+A+ A + +T TAA GT Y++PE V +SDVYS G ++ E+++G Sbjct: 158 GIARAIADSGNSVTQTAAVIGTAQYLSPE--QARGDSVDARSDVYSLGCVLYEVLTGEPP 215 Query: 513 --RNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNP 340 +S SV YQ H E +A + L V L + NP Sbjct: 216 FTGDSPVSVAYQ----------------HVREDPIPPSARHEGLSADLDAVVLKALAKNP 259 Query: 339 KNRPSMTKVVNMLTGRLQNLQIPPKPFVSSE 247 +NR + R+ N + P P V ++ Sbjct: 260 ENRYQTAAEMRADLVRVHNGEPPEAPKVLTD 290
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 38.1 bits (87), Expect = 0.025 Identities = 41/151 (27%), Positives = 63/151 (41%), Gaps = 5/151 (3%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAAR-GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR-- 514 G+A+ A + +T TAA GT Y++PE V +SDVYS G ++ E+++G Sbjct: 158 GIARAIADSGNSVTQTAAVIGTAQYLSPE--QARGDSVDARSDVYSLGCVLYEVLTGEPP 215 Query: 513 --RNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNP 340 +S SV YQ H E +A + L V L + NP Sbjct: 216 FTGDSPVSVAYQ----------------HVREDPIPPSARHEGLSADLDAVVLKALAKNP 259 Query: 339 KNRPSMTKVVNMLTGRLQNLQIPPKPFVSSE 247 +NR + R+ N + P P V ++ Sbjct: 260 ENRYQTAAEMRADLVRVHNGEPPEAPKVLTD 290
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 37.7 bits (86), Expect = 0.033 Identities = 32/128 (25%), Positives = 58/128 (45%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA++ D A+ + + APE NFG + KSDV+SFG+L++E+V+ R Sbjct: 377 GLARII-EDNEYTAREGAKFPIKWTAPEAI--NFGSFTIKSDVWSFGILLMEIVTYGRIP 433 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + + + E H + + E +L + + C + P+ RP+ Sbjct: 434 YPGMSNPEVIRALE---------HGYRMPRPDNCPE-----ELYSIMIRCWKNRPEERPT 479 Query: 324 MTKVVNML 301 + ++L Sbjct: 480 FEYIQSVL 487
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 37.7 bits (86), Expect = 0.033 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLAK A D +I GT Y+APE + G ++D+YS G+++ E++SGR Sbjct: 264 GLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLDG---RADLYSLGVILYELLSGRPP 320 Query: 507 SDPSVEYQ 484 D ++ Sbjct: 321 FDAKTPHE 328
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 37.4 bits (85), Expect = 0.043 Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 2/145 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ +D + AR + ++APE ++ R + + +SDV+SFG+L+ E+ S + Sbjct: 1041 GLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVY---TIQSDVWSFGVLLWEIFSLGAS 1097 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ +E + G T E + M L C +PK RP Sbjct: 1098 PYPGVKIDEE------FCRRLKEGTRMRAPDYTTPEMYQTM-------LDCWHGDPKQRP 1144 Query: 327 SMTKVVNMLTGRLQ-NLQIPPKPFV 256 + +++V L LQ N++ K +V Sbjct: 1145 TFSELVEHLGNLLQANVRQDGKDYV 1169
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 37.4 bits (85), Expect = 0.043 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 9/137 (6%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSY--KSDVYSFGMLVLEM----- 526 G+A+ C R + + + GT G+ APEV G V Y ++DVYSFG+L+ ++ Sbjct: 2019 GIAQYCCR----MGIKTSEGTPGFRAPEVAR---GNVIYNQQADVYSFGLLLHDIWTTGS 2071 Query: 525 --VSGRRNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCI 352 + G R + E + LP+ V E + W + ++ + C+ Sbjct: 2072 RIMEGLRFPNEFDELAIQGKLPDPVKEYGCA--PWPMVEKLITK--------------CL 2115 Query: 351 QWNPKNRPSMTKVVNML 301 + NP+ RP+ +V ++L Sbjct: 2116 KENPQERPTSAQVFDIL 2132
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 37.4 bits (85), Expect = 0.043 Identities = 36/137 (26%), Positives = 65/137 (47%), Gaps = 3/137 (2%) Frame = -3 Query: 663 RDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR--NSDPS-V 493 + S I +T + PE Y R G +S K+DVYSFG++++E+++G + DP V Sbjct: 336 QQSSTINMTGGGRKHLWYMPEEYIRQ-GRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHV 394 Query: 492 EYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKV 313 + +D L E + + + L ++ + +L +A C+ K RP+M +V Sbjct: 395 QLRD--LLMELMEKRGLDSCLSFLDRKIPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEV 452 Query: 312 VNMLTGRLQNLQIPPKP 262 ++ L +L P Sbjct: 453 LSSLESTQPSLYFAEDP 469
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 37.4 bits (85), Expect = 0.043 Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 7/87 (8%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR--- 514 G+A+ A S+ A GT Y++PE V +SDVYS G ++ E+++G Sbjct: 158 GIARAIADSTSVTQTAAVIGTAQYLSPE--QARGDSVDARSDVYSLGCVLYEILTGEPPF 215 Query: 513 -RNSDPSVEYQ---DEVYLPEWVYEGV 445 +S SV YQ ++ P +EG+ Sbjct: 216 IGDSPVSVAYQHVREDPIPPSQRHEGI 242
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 37.4 bits (85), Expect = 0.043 Identities = 25/77 (32%), Positives = 40/77 (51%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA++ D A+ + + APE NFG + KSDV+SFG+L++E+V+ R Sbjct: 398 GLARII-EDNEYTAREGAKFPIKWTAPEAI--NFGSFTIKSDVWSFGILLMEIVTYGRIP 454 Query: 504 DPSVEYQDEVYLPEWVY 454 P + + + E Y Sbjct: 455 YPGMSNPEVIRALEHGY 471
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 37.0 bits (84), Expect = 0.057 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT ++APE+Y G + K D+Y+FGM +LEM +G Sbjct: 175 GTPEFMAPEMYEEQ--GYNEKVDIYAFGMCLLEMATG 209
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 37.0 bits (84), Expect = 0.057 Identities = 34/120 (28%), Positives = 55/120 (45%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 409 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 465 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ + A E M Q C + +P+ RP+ Sbjct: 466 YPGMNNRE-------VLEQVERGYRMPCPQDCPASLHELMLQ-------CWKKDPEERPT 511
>ZYG1_CAEEL (Q9GT24) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 706 Score = 37.0 bits (84), Expect = 0.057 Identities = 20/57 (35%), Positives = 33/57 (57%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLA R ++ T+ GT G+IAP+VY + + + +DVYS G ++ M++ R Sbjct: 155 GLATTLGRGETTCTIV---GTPGFIAPQVYDQEY---TQSADVYSLGAVLYTMLTAR 205
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 37.0 bits (84), Expect = 0.057 Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 3/130 (2%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYL 469 I +A RGT+ YI PE++ N + DVYSF +++ E+++ ++ Y + Sbjct: 191 IERSALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKK------PYAGLNMM 244 Query: 468 PEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKV---VNMLT 298 + V +G L +++ E E++ Q+ + C +PK RP V +ML Sbjct: 245 T--IIIRVAAGMRPSL-QDVSDEWPEEVHQMVNLMKRCWDQDPKKRPCFLNVAVETDMLL 301 Query: 297 GRLQNLQIPP 268 Q+ P Sbjct: 302 SLFQSPMTDP 311
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 36.6 bits (83), Expect = 0.074 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 2/145 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ +D + AR + ++APE ++ R + + +SDV+SFG+L+ E+ S + Sbjct: 1046 GLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVY---TIQSDVWSFGVLLWEIFSLGAS 1102 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ +E + G T E + M L C +P RP Sbjct: 1103 PYPGVKIDEE------FCRRLKEGTRMRAPDYTTPEMYQTM-------LDCWHEDPNQRP 1149 Query: 327 SMTKVVNMLTGRLQ-NLQIPPKPFV 256 S +++V L LQ N Q K ++ Sbjct: 1150 SFSELVEHLGNLLQANAQQDGKDYI 1174
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 36.6 bits (83), Expect = 0.074 Identities = 23/64 (35%), Positives = 36/64 (56%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA++ D A+ + + APE NFG + KSDV+SFG+L++E+V+ R Sbjct: 400 GLARVI-EDNEYTAREGAKFPIKWTAPEAI--NFGSFTIKSDVWSFGILLMEIVTYGRIP 456 Query: 504 DPSV 493 P + Sbjct: 457 YPGM 460
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 36.6 bits (83), Expect = 0.074 Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Frame = -3 Query: 681 LAKLCARDQSIITLTAARGTMGYIAPEVY-SRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 +A + R+ I T+ GT Y+APE++ SR G S+ D +S G+ E++ GRR Sbjct: 167 IAAMLPRETQITTMA---GTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRR 221
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 36.6 bits (83), Expect = 0.074 Identities = 27/107 (25%), Positives = 54/107 (50%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT YIAPEV G S++ D++S G+++ ++ G+ P + +D +YE Sbjct: 241 GTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGK----PPFQARD----VNTIYER 292 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 I ++ + ++ K+ I++L +P RPS+T++++ Sbjct: 293 -IKCRDFSFPRDKPISDEGKILIRDILSL-----DPIERPSLTEIMD 333
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 36.6 bits (83), Expect = 0.074 Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 13/141 (9%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEV----YSRNFGGVSY---------KSDVYSFG 544 GL+K T RGT ++APEV Y G +S+ KSDVYSFG Sbjct: 1156 GLSKTKDSSTRYSNQTWNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFG 1215 Query: 543 MLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVA 364 M+ E+++G V + +E P V V+ G +L + E K + Sbjct: 1216 MVCYEVLTG------DVPFPEEKN-PNNVKRMVLEGVRPDLPAHCPIELKALITD----- 1263 Query: 363 LWCIQWNPKNRPSMTKVVNML 301 C +P RPS + L Sbjct: 1264 --CWNQDPLKRPSFAVICQKL 1282
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 36.6 bits (83), Expect = 0.074 Identities = 23/64 (35%), Positives = 36/64 (56%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA++ D A+ + + APE NFG + KSDV+SFG+L++E+V+ R Sbjct: 378 GLARII-EDNEYTAREGAKFPIKWTAPEAI--NFGSSTIKSDVWSFGILLMEIVTYGRIP 434 Query: 504 DPSV 493 P + Sbjct: 435 YPGM 438
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 36.2 bits (82), Expect = 0.096 Identities = 17/37 (45%), Positives = 28/37 (75%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G S+ +D +S+G+L+ EM++G Sbjct: 242 GTVEYMAPEVVNRQ--GHSHSADWWSYGVLMFEMLTG 276
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 36.2 bits (82), Expect = 0.096 Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 2/76 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTA-ARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA R + ++ RG+ Y+APEV G + ++D++S G+L+ +++G+ Sbjct: 162 GLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTP 221 Query: 507 SD-PSVEYQDEVYLPE 463 + PS+E +D V+ E Sbjct: 222 WELPSLENEDFVFFIE 237
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 36.2 bits (82), Expect = 0.096 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+ Y+APE+ + G +D++S G V+EM +GR Sbjct: 532 GTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGR 569
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 36.2 bits (82), Expect = 0.096 Identities = 17/37 (45%), Positives = 28/37 (75%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G S+ +D +S+G+L+ EM++G Sbjct: 224 GTVEYMAPEVVNRQ--GHSHSADWWSYGVLMFEMLTG 258
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 36.2 bits (82), Expect = 0.096 Identities = 17/37 (45%), Positives = 28/37 (75%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G S+ +D +S+G+L+ EM++G Sbjct: 224 GTVEYMAPEVVNRQ--GHSHSADWWSYGVLMFEMLTG 258
>GCN2_SCHPO (Q9HGN1) Serine/threonine-protein kinase gcn2 (EC 2.7.11.1)| Length = 1576 Score = 36.2 bits (82), Expect = 0.096 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 6/132 (4%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSY--KSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYL 469 LT GT Y+APE+ SR GV Y K D+YS G+++ EM S + D + Sbjct: 817 LTTGVGTALYVAPELLSRR-NGVRYDAKVDMYSLGIILFEMCMTFSTSMERIRIIDTIRS 875 Query: 468 PEWVYEGVI----SGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 P + + HE++ V +Q +P RPS ++ Sbjct: 876 PSISFPSTFPFSRASHEFK------------------VIHCLLQHDPTKRPSSQEL---- 913 Query: 300 TGRLQNLQIPPK 265 L++ IPPK Sbjct: 914 ---LESEAIPPK 922 Score = 35.4 bits (80), Expect = 0.16 Identities = 15/34 (44%), Positives = 22/34 (64%) Frame = -3 Query: 618 GYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 G PEV +F S K+D++ FG+LVL+M+ G Sbjct: 425 GLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCG 458
>WNK3_HUMAN (Q9BYP7) Serine/threonine-protein kinase WNK3 (EC 2.7.11.1)| (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 35.8 bits (81), Expect = 0.13 Identities = 30/107 (28%), Positives = 53/107 (49%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APE+Y ++ DVY+FGM +LEM + + P E Q+ +Y Sbjct: 311 GTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 360 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 V SG + +++T E +++ + CI+ N R S+ ++N Sbjct: 361 VTSGIKPASFNKVTDPEVKEIIE------GCIRQNKSERLSIRDLLN 401
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 35.8 bits (81), Expect = 0.13 Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 1/52 (1%) Frame = -3 Query: 669 CAR-DQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 CA+ D ++ T GT ++APEV +R G +K DV+S G++ +EMV G Sbjct: 527 CAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYG--FKVDVWSLGIMAIEMVEG 576
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 35.8 bits (81), Expect = 0.13 Identities = 18/40 (45%), Positives = 27/40 (67%) Frame = -3 Query: 630 RGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 RGT+ ++APE+ G S K D++S G +VLEM +G+R Sbjct: 1340 RGTVFWMAPEMVDTK-QGYSAKVDIWSLGCIVLEMFAGKR 1378
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 35.8 bits (81), Expect = 0.13 Identities = 33/123 (26%), Positives = 51/123 (41%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPE 463 L ++R + + APE G S KSDV+SFG+L+ E+ S R P + ++ Sbjct: 341 LDSSRLPVKWTAPEALKN--GRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKE------ 392 Query: 462 WVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQN 283 V E V G+ E M C + P RP K+V L L++ Sbjct: 393 -VSEAVEKGYRMEPPDSCPGPVHTLMGS-------CWEAEPSRRPPFRKIVEKLGRELRS 444 Query: 282 LQI 274 + + Sbjct: 445 VGV 447
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.8 bits (81), Expect = 0.13 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 7/68 (10%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVS----- 520 GLA++ D A+ + + APE NFG + KSDV+SFG+L+ E+V+ Sbjct: 386 GLARVI-EDNEYTAREGAKFPIKWTAPEAI--NFGCFTIKSDVWSFGILLYEIVTYGKIP 442 Query: 519 --GRRNSD 502 GR N+D Sbjct: 443 YPGRTNAD 450
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.8 bits (81), Expect = 0.13 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 7/68 (10%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVS----- 520 GLA++ D A+ + + APE NFG + KSDV+SFG+L+ E+V+ Sbjct: 386 GLARVI-EDNEYTAREGAKFPIKWTAPEAI--NFGCFTIKSDVWSFGILLYEIVTYGKIP 442 Query: 519 --GRRNSD 502 GR N+D Sbjct: 443 YPGRTNAD 450
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.8 bits (81), Expect = 0.13 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 7/68 (10%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVS----- 520 GLA++ D A+ + + APE NFG + KSDV+SFG+L+ E+V+ Sbjct: 386 GLARVI-EDNEYTAREGAKFPIKWTAPEAI--NFGCFTIKSDVWSFGILLYEIVTYGKIP 442 Query: 519 --GRRNSD 502 GR N+D Sbjct: 443 YPGRTNAD 450
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 35.8 bits (81), Expect = 0.13 Identities = 27/109 (24%), Positives = 55/109 (50%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT GY APE+ R K D++S+GM++ E++SG+R P++ + ++ + + + +G Sbjct: 1426 GTPGYQAPEIRPRIV--YDEKVDMFSYGMVLYELLSGQR---PALGHH-QLQIVKKLSKG 1479 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 + + E+ + +L + + C P+ RP VV+ + Sbjct: 1480 I--------RPVLGQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQM 1520
>GRK7_HUMAN (Q8WTQ7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 35.8 bits (81), Expect = 0.13 Identities = 20/56 (35%), Positives = 31/56 (55%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEV 475 +T GT GY+APE+ SY D ++ G + EMV+GR P +Y+++V Sbjct: 347 ITQRAGTNGYMAPEILMEKVS-YSYPVDWFAMGCSIYEMVAGR---TPFKDYKEKV 398
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 35.8 bits (81), Expect = 0.13 Identities = 35/128 (27%), Positives = 55/128 (42%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 416 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 472 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ E MRQ C + P RP+ Sbjct: 473 YPGMVNRE-------VLEQVDRGYRMPCPQGCPESLHEMMRQ-------CWKKEPDERPT 518 Query: 324 MTKVVNML 301 + + L Sbjct: 519 FEYIQSFL 526
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 35.8 bits (81), Expect = 0.13 Identities = 34/128 (26%), Positives = 56/128 (43%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R Sbjct: 382 GLARLI-EDNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTYGRIP 438 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + + V + + G+ E E M Q C + P+ RP+ Sbjct: 439 YPGMTNPE-------VIQNLERGYRMPQPDNCPQELYELMMQ-------CWKEQPEERPT 484 Query: 324 MTKVVNML 301 + ++L Sbjct: 485 FEYMKSVL 492
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 35.8 bits (81), Expect = 0.13 Identities = 16/52 (30%), Positives = 34/52 (65%) Frame = -3 Query: 666 ARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 ++ ++ + RGT+ Y+ PE Y + G ++ +D +SFG+++LE ++G+R Sbjct: 373 SQSSTVARTSTVRGTLAYL-PEEYIKT-GRLAVDTDTFSFGVVILETLAGQR 422
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 35.8 bits (81), Expect = 0.13 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 12/71 (16%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG------------RRNSDPSVEYQ 484 GT+GY+APEV + G+S D + G L+ EM+ G R D V Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLET 404 Query: 483 DEVYLPEWVYE 451 +EVY P++ E Sbjct: 405 EEVYSPKFSEE 415
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 35.4 bits (80), Expect = 0.16 Identities = 35/134 (26%), Positives = 67/134 (50%), Gaps = 1/134 (0%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ +D + +AR + ++APE ++ + + + +SDV+SFG+L+ E+ S + Sbjct: 1057 GLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVY---TTQSDVWSFGVLLWEIFSLGAS 1113 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ +E + + +G + M A E + + L C +PK RP Sbjct: 1114 PYPGVQINEE--FCQRLRDG----------TRMRAPEL-ATPAIRRIMLNCWSGDPKARP 1160 Query: 327 SMTKVVNMLTGRLQ 286 + +++V +L LQ Sbjct: 1161 AFSELVEILGDLLQ 1174
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 35.4 bits (80), Expect = 0.16 Identities = 17/37 (45%), Positives = 28/37 (75%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G S+ +D +S+G+L+ EM++G Sbjct: 224 GTVEYMAPEVVNRQ--GHSHGADWWSYGVLMFEMLTG 258
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 35.4 bits (80), Expect = 0.16 Identities = 20/56 (35%), Positives = 36/56 (64%) Frame = -3 Query: 678 AKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 + + AR Q++ RGT+ Y+ PE Y + G ++ +D +SFG++VLE ++G+R Sbjct: 375 SSMVARTQTV------RGTLAYL-PEEYIKT-GRLAVDTDTFSFGVVVLETLAGQR 422
>GRK7_PIG (Q8WP15) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 35.4 bits (80), Expect = 0.16 Identities = 19/56 (33%), Positives = 31/56 (55%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEV 475 +T GT GY+APE+ SY D ++ G + EMV+GR P +Y++++ Sbjct: 347 VTQRAGTNGYMAPEILMEK-ASYSYPVDWFAMGCSIYEMVAGR---TPFKDYKEKI 398
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 35.4 bits (80), Expect = 0.16 Identities = 38/145 (26%), Positives = 64/145 (44%), Gaps = 2/145 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ +D + AR + ++APE ++ R + + +SDV+SFG+L+ E+ S + Sbjct: 1048 GLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVY---TIQSDVWSFGVLLWEIFSLGAS 1104 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ +E + G T E + M L C P RP Sbjct: 1105 PYPGVKIDEE------FCRRLKEGTRMRAPDYTTPEMYQTM-------LDCWHGEPSQRP 1151 Query: 327 SMTKVVNMLTGRLQ-NLQIPPKPFV 256 + +++V L LQ N Q K ++ Sbjct: 1152 TFSELVEHLGNLLQANAQQDGKDYI 1176
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 35.4 bits (80), Expect = 0.16 Identities = 24/64 (37%), Positives = 37/64 (57%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D+ + AR + + APE + N+ S KSDV+SFG+L+ E+V+ R Sbjct: 390 GLARLIKEDEYEARV-GARFPIKWTAPE--AANYSKFSIKSDVWSFGILLTELVTYGRIP 446 Query: 504 DPSV 493 P + Sbjct: 447 YPGM 450
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 35.4 bits (80), Expect = 0.16 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%) Frame = -3 Query: 642 LTAARGTMGYIAPEVY-SRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 +T GT Y+APE++ SR G S+ D +S G+ E++ GRR Sbjct: 177 ITTVAGTKPYMAPEMFTSRKETGYSFAVDWWSLGVTAYELLRGRR 221
>M3K5_MOUSE (O35099) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1380 Score = 35.0 bits (79), Expect = 0.21 Identities = 13/38 (34%), Positives = 24/38 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+ Y+APE+ + G +D++S G ++EM +G+ Sbjct: 848 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 885
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 35.0 bits (79), Expect = 0.21 Identities = 33/123 (26%), Positives = 51/123 (41%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPE 463 L ++R + + APE G S KSDV+SFG+L+ E+ S R P + ++ Sbjct: 379 LDSSRLPVKWTAPEALKN--GRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKE------ 430 Query: 462 WVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQN 283 V E V G+ E M C + P RP K+V L L++ Sbjct: 431 -VSEAVEKGYRMEPPDGCPGSVHTLMGS-------CWEAEPARRPPFRKIVEKLGRELRS 482 Query: 282 LQI 274 + + Sbjct: 483 VGV 485
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 35.0 bits (79), Expect = 0.21 Identities = 13/38 (34%), Positives = 24/38 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+ Y+APE+ + G +D++S G ++EM +G+ Sbjct: 841 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 878
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/64 (35%), Positives = 35/64 (54%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R Sbjct: 383 GLARLI-EDNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILMTEIVTHGRIP 439 Query: 504 DPSV 493 P + Sbjct: 440 YPGM 443
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/64 (35%), Positives = 35/64 (54%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R Sbjct: 383 GLARLI-EDNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTHGRIP 439 Query: 504 DPSV 493 P + Sbjct: 440 YPGM 443
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/64 (35%), Positives = 35/64 (54%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R Sbjct: 383 GLARLI-EDNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTHGRIP 439 Query: 504 DPSV 493 P + Sbjct: 440 YPGM 443
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/64 (35%), Positives = 35/64 (54%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R Sbjct: 383 GLARLI-EDNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTHGRIP 439 Query: 504 DPSV 493 P + Sbjct: 440 YPGM 443
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 27/37 (72%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G + +D +SFG+L+ EM++G Sbjct: 221 GTIEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 255
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 27/37 (72%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G + +D +SFG+L+ EM++G Sbjct: 221 GTIEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 255
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 27/37 (72%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G + +D +SFG+L+ EM++G Sbjct: 230 GTVEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 264
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 27/37 (72%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G + +D +SFG+L+ EM++G Sbjct: 230 GTVEYMAPEVVNRR--GHTQSADWWSFGVLMFEMLTG 264
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/37 (43%), Positives = 28/37 (75%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G ++ +D +S+G+L+ EM++G Sbjct: 224 GTVEYMAPEVVNRQ--GHTHSADWWSYGVLMFEMLTG 258
>GUC2C_PIG (P55204) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1073 Score = 35.0 bits (79), Expect = 0.21 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 3/108 (2%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISG 436 + APE R VS K DVYS+G++ E++ RR + ++ +D+ E ++ S Sbjct: 646 WTAPEHLRR--ASVSQKGDVYSYGIIAQEIIL-RRETFYTLSCRDQ---KEKIFRVENSN 699 Query: 435 HEWELTSEM---TAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 ++ TAEEKE L + W + +P+ RP K+ N L Sbjct: 700 GVKPFRPDLFLETAEEKELEVYLLVKNCW--EEDPEKRPDFKKIENTL 745
>NIM1_NEUCR (P48479) G2-specific protein kinase nim-1 (EC 2.7.11.1)| Length = 779 Score = 35.0 bits (79), Expect = 0.21 Identities = 28/113 (24%), Positives = 51/113 (45%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT Y++PE+ + + KSD++S G ++ E+ + + YQ L + + EG Sbjct: 197 GTPFYMSPEICAAE--KYTLKSDIWSLGCIIYELCAREPPFNAKTHYQ----LVQKIKEG 250 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRL 289 I+ + E+ A K+ C++ NP RP ++N+ RL Sbjct: 251 KIAPLPSVYSGELFATIKD-----------CLRVNPDRRPDTATLLNLPIVRL 292
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 35.0 bits (79), Expect = 0.21 Identities = 20/50 (40%), Positives = 31/50 (62%) Frame = -3 Query: 666 ARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 AR+ T +A GT ++APEV + S SDV+SFG+L+ E+++G Sbjct: 252 AREWHKTTKMSAAGTYAWMAPEVIRLSL--FSKSSDVWSFGVLLWELLTG 299
>GRK7_SPETR (Q9Z2G7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 548 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/77 (29%), Positives = 34/77 (44%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPE 463 +T GT GY+APE+ SY D ++ G + EMV+GR E + L E Sbjct: 342 ITQRAGTNGYMAPEILMDK-ASYSYPVDWFAMGCSIYEMVAGRTPFKDFKEKVSKEDLKE 400 Query: 462 WVYEGVISGHEWELTSE 412 + ++ H T E Sbjct: 401 RTMKDEVAFHHENFTEE 417
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 27/37 (72%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G S +D +S+G+L+ EM++G Sbjct: 235 GTVEYMAPEVVNRR--GHSQSADWWSYGVLMFEMLTG 269
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 35.0 bits (79), Expect = 0.21 Identities = 33/120 (27%), Positives = 55/120 (45%) Frame = -3 Query: 636 AARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWV 457 A G+ ++APEV + K+DV+S+G+++ E+++ R +DP YLP Sbjct: 215 AVVGSPFWMAPEVLRDE--PYNEKADVFSYGIILCEIIA-RIQADPD-------YLPRTE 264 Query: 456 YEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQ 277 G+ +++ M + QLT C +PK RPS ++ L L LQ Sbjct: 265 NFGL----DYDAFQHMVGDCPPDFLQLTFN---CCNMDPKLRPSFVEIGKTLEEILSRLQ 317
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 34.7 bits (78), Expect = 0.28 Identities = 17/38 (44%), Positives = 25/38 (65%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+ Y+ PE+ + S SDVYSFG+LV +++GR Sbjct: 186 GTLAYLDPELLFKVNLKASKASDVYSFGILVWAVLAGR 223
>STK39_RAT (O88506) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (Pancreatic serine/threonine-protein kinase) (PS/TK) (PSTK1) Length = 553 Score = 34.7 bits (78), Expect = 0.28 Identities = 29/111 (26%), Positives = 57/111 (51%), Gaps = 5/111 (4%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APEV + G +K+D++SFG+ +E+ +G + P +Y L Sbjct: 243 GTPCWMAPEVMEQ-VRGYDFKADMWSFGITAIELATG---AAPYHKYPPMKVL------- 291 Query: 447 VISGHEWELTSEMTAEEKEKMRQL-----TIVALWCIQWNPKNRPSMTKVV 310 +++ T E E+KE M++ +++L C+Q +P RP+ +++ Sbjct: 292 MLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSL-CLQKDPSKRPTAAELL 341
>STK39_MOUSE (Q9Z1W9) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) Length = 556 Score = 34.7 bits (78), Expect = 0.28 Identities = 29/111 (26%), Positives = 57/111 (51%), Gaps = 5/111 (4%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APEV + G +K+D++SFG+ +E+ +G + P +Y L Sbjct: 246 GTPCWMAPEVMEQ-VRGYDFKADMWSFGITAIELATG---AAPYHKYPPMKVL------- 294 Query: 447 VISGHEWELTSEMTAEEKEKMRQL-----TIVALWCIQWNPKNRPSMTKVV 310 +++ T E E+KE M++ +++L C+Q +P RP+ +++ Sbjct: 295 MLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSL-CLQKDPSKRPTAAELL 344
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 34.7 bits (78), Expect = 0.28 Identities = 24/91 (26%), Positives = 42/91 (46%) Frame = -3 Query: 573 SYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEK 394 S KSD++SFG+L+ E+V+ P + D V V G+ E + + Sbjct: 665 SVKSDIWSFGILMWEIVTLGSTPYPGISAAD-------VMRKVRDGYRLE-------KPE 710 Query: 393 EKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 R+L + +C +P+ RP +++ ML Sbjct: 711 HCRRELYNIMYYCWSHDPQERPLFAEIIQML 741
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 34.7 bits (78), Expect = 0.28 Identities = 22/60 (36%), Positives = 36/60 (60%), Gaps = 3/60 (5%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMG---YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 G+A+ A D S T+T ++G +G Y++PE V +SD+YS G ++ EM++GR Sbjct: 166 GIAR--ALDDSAATMTQSQGVVGTAQYLSPE--QARGETVDMRSDLYSAGCVLYEMLTGR 221
>PBS2_YEAST (P08018) MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B| resistance protein 2) (Suppressor of fluoride sensitivity 4) Length = 668 Score = 34.7 bits (78), Expect = 0.28 Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 3/104 (2%) Frame = -3 Query: 627 GTMGYIAPE-VYSRNFGGVSY--KSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWV 457 G Y+APE + S N +Y +SD++S G+ +LEM GR P E D ++ Sbjct: 521 GCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPP--ETYDNIFSQ--- 575 Query: 456 YEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 ++ G L S+ + + + L C+Q P+ RP+ Sbjct: 576 LSAIVDGPPPRLPSDKFSSDAQDFVSL------CLQKIPERRPT 613
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 34.7 bits (78), Expect = 0.28 Identities = 36/128 (28%), Positives = 57/128 (44%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + FG + KSDV+SFG+L+ E++S R Sbjct: 425 GLARLI-EDNEYNPRQGAKFPIKWTAPE--AALFGRFTIKSDVWSFGILLTELISKGRVP 481 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ A E M Q W + +P+ RP+ Sbjct: 482 YPGMNNRE-------VLEQVEHGYHMPCPPGCPASLYEAMEQ-----TW--RLDPEERPT 527 Query: 324 MTKVVNML 301 + + L Sbjct: 528 FEYLQSFL 535
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 34.7 bits (78), Expect = 0.28 Identities = 35/120 (29%), Positives = 56/120 (46%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D T A+ + + APE + F S KSDV+SFG+L+ E+V+ R Sbjct: 234 GLARLIVSDDYNAT-EGAKFPIKWTAPE--AALFNRFSIKSDVWSFGILITELVTYGRIP 290 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + + V + + G + + +T E L + L C + NP +RP+ Sbjct: 291 YPGMSNAE-------VLQNLDKG--YRMPCPVTTPE-----SLYQIMLDCWKRNPADRPT 336
>STK39_HUMAN (Q9UEW8) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT) Length = 547 Score = 34.7 bits (78), Expect = 0.28 Identities = 29/111 (26%), Positives = 57/111 (51%), Gaps = 5/111 (4%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APEV + G +K+D++SFG+ +E+ +G + P +Y L Sbjct: 236 GTPCWMAPEVMEQ-VRGYDFKADMWSFGITAIELATG---AAPYHKYPPMKVL------- 284 Query: 447 VISGHEWELTSEMTAEEKEKMRQL-----TIVALWCIQWNPKNRPSMTKVV 310 +++ T E E+KE M++ +++L C+Q +P RP+ +++ Sbjct: 285 MLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSL-CLQKDPSKRPTAAELL 334
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 34.3 bits (77), Expect = 0.37 Identities = 28/109 (25%), Positives = 57/109 (52%), Gaps = 2/109 (1%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR--NSDPSVEYQDEVYLPEWVY 454 GT YI+PE+ +R+ G+ +SDV+S G + ++ GR ++D ++V L Sbjct: 173 GTPNYISPEIATRSAHGL--ESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLA---- 226 Query: 453 EGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 ++E+ + ++ E K+ + QL ++ NP +R S++ V++ Sbjct: 227 -------DYEMPTFLSIEAKDLIHQL-------LRRNPADRLSLSSVLD 261
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 34.3 bits (77), Expect = 0.37 Identities = 14/38 (36%), Positives = 26/38 (68%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT Y++PEV S G + SD+++FG ++ +M++G+ Sbjct: 274 GTARYVSPEVLSDKIAGTA--SDIWAFGCILFQMLAGK 309
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 34.3 bits (77), Expect = 0.37 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 1/134 (0%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ +D + +AR + ++APE ++ + + + +SDV+SFG+L+ E+ S + Sbjct: 1057 GLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVY---TTQSDVWSFGVLLWEIFSLGAS 1113 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ +E + + G T + M+ C +PK RP Sbjct: 1114 PYPGVQINEE------FCQRLKDGTRMRAPELATPAIRHIMQS-------CWSGDPKARP 1160 Query: 327 SMTKVVNMLTGRLQ 286 + + +V +L LQ Sbjct: 1161 AFSDLVEILGDLLQ 1174
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 34.3 bits (77), Expect = 0.37 Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 1/134 (0%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ +D + +AR + ++APE ++ + + + +SDV+SFG+L+ E+ S + Sbjct: 1057 GLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVY---TTQSDVWSFGVLLWEIFSLGAS 1113 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ +E + + G T + M+ C +PK RP Sbjct: 1114 PYPGVQINEE------FCQRLKDGTRMRAPELATPAIRHIMQS-------CWSGDPKARP 1160 Query: 327 SMTKVVNMLTGRLQ 286 + + +V +L LQ Sbjct: 1161 AFSDLVEILGDLLQ 1174
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 34.3 bits (77), Expect = 0.37 Identities = 34/114 (29%), Positives = 49/114 (42%), Gaps = 2/114 (1%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISG 436 + APE SR G S KSDV+SFG+L+ E+ S + P + + + V +G Sbjct: 353 WTAPEALSR--GHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHE-------TFLRVDAG 403 Query: 435 HEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTG--RLQNL 280 + E + M L C +PK RP + LTG R +NL Sbjct: 404 YRMPCPLECPPNIHKLM-------LSCWSRDPKQRPCFKDLCEKLTGITRYENL 450
>OXSR1_PONPY (Q5R495) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 34.3 bits (77), Expect = 0.37 Identities = 26/106 (24%), Positives = 52/106 (49%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APEV + G +K+D++SFG+ +E+ +G + P +Y L + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATG---AAPYHKYPPMKVLMLTLQND 243 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVV 310 S EM + + R++ + C+Q +P+ RP+ +++ Sbjct: 244 PPSLETGVQDKEMLKKYGKSFRKMISL---CLQKDPEKRPTAAELL 286
>OXSR1_MOUSE (Q6P9R2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 34.3 bits (77), Expect = 0.37 Identities = 26/106 (24%), Positives = 52/106 (49%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APEV + G +K+D++SFG+ +E+ +G + P +Y L + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATG---AAPYHKYPPMKVLMLTLQND 243 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVV 310 S EM + + R++ + C+Q +P+ RP+ +++ Sbjct: 244 PPSLETGVQDKEMLKKYGKSFRKMISL---CLQKDPEKRPTAAELL 286
>OXSR1_HUMAN (O95747) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 34.3 bits (77), Expect = 0.37 Identities = 26/106 (24%), Positives = 52/106 (49%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APEV + G +K+D++SFG+ +E+ +G + P +Y L + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATG---AAPYHKYPPMKVLMLTLQND 243 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVV 310 S EM + + R++ + C+Q +P+ RP+ +++ Sbjct: 244 PPSLETGVQDKEMLKKYGKSFRKMISL---CLQKDPEKRPTAAELL 286
>M3K8_RAT (Q63562) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (Tumor progression locus 2) (TPL-2) Length = 467 Score = 34.3 bits (77), Expect = 0.37 Identities = 38/132 (28%), Positives = 60/132 (45%) Frame = -3 Query: 630 RGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYE 451 RGT Y++PEV G S K+D+YS G ++ M +G + P V+ P ++Y Sbjct: 288 RGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY- 341 Query: 450 GVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQIP 271 I + ++ + MR+L AL + NP +RP K ++L N P Sbjct: 342 --IIHKQAPPLEDIAGDCSPGMRELIEAAL---ERNPNHRP---KAADLLKHEALN---P 390 Query: 270 PKPFVSSENHPR 235 P+ E+ PR Sbjct: 391 PR-----EDQPR 397
>M3K8_MOUSE (Q07174) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 34.3 bits (77), Expect = 0.37 Identities = 38/132 (28%), Positives = 60/132 (45%) Frame = -3 Query: 630 RGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYE 451 RGT Y++PEV G S K+D+YS G ++ M +G + P V+ P ++Y Sbjct: 288 RGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY- 341 Query: 450 GVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQIP 271 I + ++ + MR+L AL + NP +RP K ++L N P Sbjct: 342 --IIHKQAPPLEDIAGDCSPGMRELIEAAL---ERNPNHRP---KAADLLKHEALN---P 390 Query: 270 PKPFVSSENHPR 235 P+ E+ PR Sbjct: 391 PR-----EDQPR 397
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVE-- 490 +T T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E Sbjct: 562 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 619 Query: 489 YQDEVYLPEWVYEGVIS 439 D+V P W+ + +S Sbjct: 620 LHDDVLYPVWLSKEAVS 636
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVE-- 490 +T T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E Sbjct: 562 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 619 Query: 489 YQDEVYLPEWVYEGVIS 439 D+V P W+ + +S Sbjct: 620 LHDDVLYPVWLSKEAVS 636
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVE-- 490 +T T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E Sbjct: 562 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 619 Query: 489 YQDEVYLPEWVYEGVIS 439 D+V P W+ + +S Sbjct: 620 LHDDVLYPVWLSKEAVS 636
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 34.3 bits (77), Expect = 0.37 Identities = 16/38 (42%), Positives = 24/38 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+GY+APEV ++ D +SFG L+ EM+ G+ Sbjct: 471 GTVGYMAPEVIDNE--KYAFSPDWFSFGCLLYEMIEGQ 506
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 34.3 bits (77), Expect = 0.37 Identities = 33/128 (25%), Positives = 57/128 (44%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 409 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 465 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ + E M + C + +P+ RP+ Sbjct: 466 YPGMNNRE-------VLEQVERGYRMPCPQDCPISLHELM-------IHCWKKDPEERPT 511 Query: 324 MTKVVNML 301 + + L Sbjct: 512 FEYLQSFL 519
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 34.3 bits (77), Expect = 0.37 Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 11/110 (10%) Frame = -3 Query: 660 DQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVS-------GRRNSD 502 D + T + + + +PEV+S F S KSDV+SFG+L+ E+ S R NS+ Sbjct: 509 DDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE 566 Query: 501 --PSVEYQDEVYLPEWVYEGV--ISGHEWELTSEMTAEEKEKMRQLTIVA 364 + +Y P V I H W+ E +RQL +A Sbjct: 567 VVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIA 616
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 34.3 bits (77), Expect = 0.37 Identities = 17/37 (45%), Positives = 26/37 (70%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT+ Y+APEV +R G S +D +S G+L+ EM++G Sbjct: 266 GTVEYMAPEVINRR--GHSMAADFWSLGVLMFEMLTG 300
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 34.3 bits (77), Expect = 0.37 Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 7/64 (10%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN-SDPSVE------YQDEVYL 469 GT Y+APE+ S+ G K DV+S G+++ +V+G +DP+V Y+ E Sbjct: 184 GTPAYVAPEILSKK-GYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRF 242 Query: 468 PEWV 457 P W+ Sbjct: 243 PRWM 246
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 34.3 bits (77), Expect = 0.37 Identities = 34/128 (26%), Positives = 56/128 (43%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + FG + KSDV+SFG+L+ E+V+ R Sbjct: 408 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALFGKFTIKSDVWSFGILLTELVTKGRVP 464 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ + + M Q C + P+ RP+ Sbjct: 465 YPGMNNRE-------VLEQVERGYRMQCPGGCPPSLHDVMVQ-------CWKREPEERPT 510 Query: 324 MTKVVNML 301 + + L Sbjct: 511 FEYLQSFL 518
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 34.3 bits (77), Expect = 0.37 Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 1/129 (0%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEM-VSGRRN 508 G+A+ DQ + + A+ + + PEV+ N+ S KSDV+SFG+L+ E+ GR Sbjct: 509 GMARYFLDDQ-YTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEVFTEGRMP 565 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 + Y+ V V GH + K + V L C Q P+ RP Sbjct: 566 FEKYTNYE--------VVTMVTRGHR-------LYQPKLASNYVYEVMLRCWQEKPEGRP 610 Query: 327 SMTKVVNML 301 S ++ + Sbjct: 611 SFEDLLRTI 619
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 34.3 bits (77), Expect = 0.37 Identities = 20/50 (40%), Positives = 31/50 (62%) Frame = -3 Query: 666 ARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 AR+ T +A GT ++APEV + S SDV+SFG+L+ E+++G Sbjct: 271 AREWHKTTQMSAAGTYAWMAPEVIKAST--FSKGSDVWSFGVLLWELLTG 318
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVE-- 490 +T T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E Sbjct: 561 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 618 Query: 489 YQDEVYLPEWVYEGVIS 439 D+V P W+ + +S Sbjct: 619 LHDDVLYPVWLSKEAVS 635
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 34.3 bits (77), Expect = 0.37 Identities = 32/120 (26%), Positives = 55/120 (45%) Frame = -3 Query: 636 AARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWV 457 A G+ ++APEV + K+DV+S+G+++ E+++ R +DP YLP Sbjct: 215 AVVGSPFWMAPEVLRDE--PYNEKADVFSYGIILCEIIA-RIQADPD-------YLPRTE 264 Query: 456 YEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQ 277 G+ +++ M + QLT C +PK RPS ++ L + LQ Sbjct: 265 NFGL----DYDAFQHMVGDCPSDFLQLTFN---CCNMDPKLRPSFEEIGKTLEEIMSRLQ 317
>OXSR1_PIG (Q863I2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 529 Score = 34.3 bits (77), Expect = 0.37 Identities = 26/106 (24%), Positives = 52/106 (49%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APEV + G +K+D++SFG+ +E+ +G + P +Y L + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATG---AAPYHKYPPMKVLMLTLQND 243 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVV 310 S EM + + R++ + C+Q +P+ RP+ +++ Sbjct: 244 PPSLETGVQDKEMLKKYGKSFRKMISL---CLQKDPEKRPTAAELL 286
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 34.3 bits (77), Expect = 0.37 Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISG 436 ++APE S G + SD++SFG+++ E+ S L E Y+G+ + Sbjct: 1202 WMAPE--SLKDGVFTTSSDMWSFGVVLWEITS----------------LAEQPYQGLSNE 1243 Query: 435 H--EWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 262 ++ + + ++T + C Q+NPK RP+ ++VN+L L + P Sbjct: 1244 QVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDL-HPSFPEVS 1302 Query: 261 FVSSENH 241 F SE + Sbjct: 1303 FFHSEEN 1309
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 33.9 bits (76), Expect = 0.48 Identities = 29/107 (27%), Positives = 50/107 (46%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ +Y Sbjct: 385 GTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRR 434 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 V SG + + +K + ++ + CI+ N R S+ ++N Sbjct: 435 VTSG------VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>WNK1_HUMAN (Q9H4A3) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein) Length = 2382 Score = 33.9 bits (76), Expect = 0.48 Identities = 29/107 (27%), Positives = 50/107 (46%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ +Y Sbjct: 385 GTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRR 434 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 V SG + + +K + ++ + CI+ N R S+ ++N Sbjct: 435 VTSG------VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 33.9 bits (76), Expect = 0.48 Identities = 15/46 (32%), Positives = 28/46 (60%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 I +A RG + YI PE++ + K DVYSF +++ E+++ ++ Sbjct: 179 IERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKK 224
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 33.9 bits (76), Expect = 0.48 Identities = 33/120 (27%), Positives = 54/120 (45%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 409 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 465 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ + E M L C + +P+ RP+ Sbjct: 466 YPGMNNRE-------VLEQVERGYRMPCPQDCPISLHELM-------LNCWKKDPEERPT 511
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 33.9 bits (76), Expect = 0.48 Identities = 29/112 (25%), Positives = 55/112 (49%), Gaps = 2/112 (1%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISG 436 ++APE S G + SDV+SFG+++ E+V+ L E Y+G+ + Sbjct: 1158 WMAPE--SLKDGIFTTHSDVWSFGVVLWEIVT----------------LAEQPYQGLSNE 1199 Query: 435 H--EWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQ 286 ++ + + E ++ QL + C Q NP+ RP+ T+++N + L+ Sbjct: 1200 QVLKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQKELR 1251
>SPKA_SYNY3 (Q9FAB3) Serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 521 Score = 33.9 bits (76), Expect = 0.48 Identities = 34/125 (27%), Positives = 52/125 (41%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+AKL + T A GT+ Y +PE + +SD+YS G+++ EM++G Sbjct: 172 GIAKLVQAAEESKT-QAFMGTLAYCSPEQMEGK--ELDSRSDIYSLGVMMYEMLTGEMPL 228 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P D W YE H +A K L + + C+ +PK RP Sbjct: 229 FP-----DNSSFGGW-YE----AHHHTKPHPFSARYKIP-ASLEALVMNCLAKSPKGRPQ 277 Query: 324 MTKVV 310 V+ Sbjct: 278 SVDVI 282
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 33.9 bits (76), Expect = 0.48 Identities = 32/120 (26%), Positives = 54/120 (45%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 406 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 462 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ + E M + C + +P+ RP+ Sbjct: 463 YPGMNNRE-------VLEQVERGYRMPCPQDCPISLHELM-------IHCWKKDPEERPT 508
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 33.9 bits (76), Expect = 0.48 Identities = 32/120 (26%), Positives = 54/120 (45%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 406 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 462 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ + E M + C + +P+ RP+ Sbjct: 463 YPGMNNRE-------VLEQVERGYRMPCPQDCPISLHELM-------IHCWKKDPEERPT 508
>WNK1_RAT (Q9JIH7) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2126 Score = 33.9 bits (76), Expect = 0.48 Identities = 29/107 (27%), Positives = 50/107 (46%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ +Y Sbjct: 385 GTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRR 434 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 V SG + + +K + ++ + CI+ N R S+ ++N Sbjct: 435 VTSG------VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 33.9 bits (76), Expect = 0.48 Identities = 19/42 (45%), Positives = 28/42 (66%), Gaps = 2/42 (4%) Frame = -3 Query: 636 AARGTMGYIAPEVYSRNFGGVSYKS--DVYSFGMLVLEMVSG 517 A+ GT GY+APEV S+ G SY S D +SFG ++ +++ G Sbjct: 350 ASVGTHGYMAPEVLSK---GTSYDSCADWFSFGCMLYKLLKG 388
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 33.9 bits (76), Expect = 0.48 Identities = 34/128 (26%), Positives = 58/128 (45%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L +D ++ + + APE + FG + KSDV+SFG+L+ E+++ R Sbjct: 402 GLARLI-KDDEYNPCQGSKFPIKWTAPE--AALFGRFTIKSDVWSFGILLTELITKGRIP 458 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ A E M Q W + +P+ RP+ Sbjct: 459 YPGMNKRE-------VLEQVEQGYHMPCPPGCPASLYEAMEQ-----TW--RLDPEERPT 504 Query: 324 MTKVVNML 301 + + L Sbjct: 505 FEYLQSFL 512
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 33.9 bits (76), Expect = 0.48 Identities = 36/154 (23%), Positives = 73/154 (47%), Gaps = 4/154 (2%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSY--KSDVYSFGMLVLEMVSGRR 511 GLAK + + S+ GT+ Y++PE+ GV Y KSD+++ G ++ E+++ R Sbjct: 178 GLAKQLSSEYSMAETCV--GTLYYMSPEICQ----GVKYSFKSDIWAVGCVLYELLTLTR 231 Query: 510 NSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNR 331 D + + + L + +G W + + T +E L V C++ +P+ R Sbjct: 232 TFDAT----NPLNLCVKIVQG-----NWAVGLDNTVYTQE----LIEVVHACLEQDPEKR 278 Query: 330 PSMTKVVN--MLTGRLQNLQIPPKPFVSSENHPR 235 P+ +++ +L+ R ++++ S PR Sbjct: 279 PTADEILERPILSWRRRDMEEKVSMLNRSNKKPR 312
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 33.5 bits (75), Expect = 0.63 Identities = 31/123 (25%), Positives = 59/123 (47%), Gaps = 2/123 (1%) Frame = -3 Query: 660 DQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQD 481 D I+ + A+ + + PEV+ +F S KSDV+SFG+L+ E+ ++ + +++ Sbjct: 417 DDEYISSSGAKFPVKWCPPEVF--HFNKYSSKSDVWSFGVLMWEVF-----TEGKMPFEN 469 Query: 480 EVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTI--VALWCIQWNPKNRPSMTKVVN 307 + L V E + G + + +TI V C +PK RP+ +++ Sbjct: 470 KSNLQ--VVEAISQGFRL---------YRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQ 518 Query: 306 MLT 298 +LT Sbjct: 519 VLT 521
>PKNH_MYCBO (Q7U095) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 596 Score = 33.5 bits (75), Expect = 0.63 Identities = 16/48 (33%), Positives = 30/48 (62%) Frame = -3 Query: 660 DQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 D+ + L A GT Y+APE +S + V+Y++D+Y+ ++ E ++G Sbjct: 166 DEKLTQLGTAVGTWKYMAPERFSND--EVTYRADIYALACVLHECLTG 211
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 33.5 bits (75), Expect = 0.63 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Frame = -3 Query: 654 SIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR----NSDPSVEY 487 SI + GT Y++PE G +SDVYS G+LV E+++G +S S+ Y Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTGHTPFTGDSALSIAY 228 Query: 486 Q 484 Q Sbjct: 229 Q 229
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 33.5 bits (75), Expect = 0.63 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Frame = -3 Query: 654 SIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR----NSDPSVEY 487 SI + GT Y++PE G +SDVYS G+LV E+++G +S S+ Y Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTGHTPFTGDSALSIAY 228 Query: 486 Q 484 Q Sbjct: 229 Q 229
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 33.5 bits (75), Expect = 0.63 Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 1/58 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAAR-GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLAK A Q+ ++ T GT Y+APE+ N + + D+YS G++ EM++G+ Sbjct: 160 GLAK--AASQATLSSTGMLLGTAAYLAPEMIENN--QATAQGDLYSVGIMAWEMLTGK 213
>PKNH_MYCTU (Q11053) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 626 Score = 33.5 bits (75), Expect = 0.63 Identities = 16/48 (33%), Positives = 30/48 (62%) Frame = -3 Query: 660 DQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 D+ + L A GT Y+APE +S + V+Y++D+Y+ ++ E ++G Sbjct: 166 DEKLTQLGTAVGTWKYMAPERFSND--EVTYRADIYALACVLHECLTG 211
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 33.5 bits (75), Expect = 0.63 Identities = 27/107 (25%), Positives = 52/107 (48%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT YIAPEV S+ G S++ DV+S G ++ ++ G+ + S E YL Sbjct: 213 GTPNYIAPEVLSKK--GHSFEVDVWSIGCIMYTLLVGKPPFETSC--LKETYLR------ 262 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 I +E+ + + ++++ +Q +P RP++ +++N Sbjct: 263 -IKKNEYSIPKHINPVAASLIQKM-------LQTDPTARPTINELLN 301
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 33.5 bits (75), Expect = 0.63 Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Frame = -3 Query: 684 GLAKLCARD--QSIITLTAARGTMGYIAPEVYSRNFGG-VSYKSDVYSFGMLVLEMVSGR 514 G+A+L D S+ + GT Y++PE + G V +SD+YSFG+L ++SGR Sbjct: 158 GIARLVEPDAASSVSQIGVVLGTPEYLSPE---QAVGAKVDTRSDLYSFGVLTYRVLSGR 214
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 33.5 bits (75), Expect = 0.63 Identities = 19/50 (38%), Positives = 31/50 (62%) Frame = -3 Query: 666 ARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 AR+ T +A GT ++APEV + S SDV+S+G+L+ E+++G Sbjct: 298 AREWHRTTKMSAAGTYAWMAPEVIRASM--FSKGSDVWSYGVLLWELLTG 345
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 33.5 bits (75), Expect = 0.63 Identities = 16/38 (42%), Positives = 24/38 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+GY+APEV + G+S D + G L+ EM+ G+ Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQ 382
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 33.5 bits (75), Expect = 0.63 Identities = 16/38 (42%), Positives = 24/38 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+GY+APEV + G+S D + G L+ EM+ G+ Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQ 382
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 33.5 bits (75), Expect = 0.63 Identities = 16/38 (42%), Positives = 24/38 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+GY+APEV + G+S D + G L+ EM+ G+ Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQ 382
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 33.5 bits (75), Expect = 0.63 Identities = 17/51 (33%), Positives = 30/51 (58%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEV 475 GT+GY+APE+ S ++ D + G L+ EM++G P +Y+++V Sbjct: 347 GTVGYMAPEIISHE--KYTFSPDWWGLGCLIYEMIAGH---SPFRKYKEKV 392
>PDK1L_BRARE (Q32PP3) Serine/threonine-protein kinase pdik1l (EC 2.7.11.1)| Length = 341 Score = 33.1 bits (74), Expect = 0.82 Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 14/119 (11%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPE 463 L+ A GT Y+APEV+ G + K+D+++ G+++ MV R + VE Q E+ L Sbjct: 215 LSTACGTDFYMAPEVWE---GHYTAKADIFALGVIIWAMV--ERITFVDVETQKEL-LGS 268 Query: 462 WVYEG---------VISGHEWELT-----SEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 +V +G ++ + EL M A K+ +R++ + NP+ RP Sbjct: 269 YVQQGEDIVPLGEALLENPKMELNIPARKKSMNASMKQLIREM-------LSANPQERP 320
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 33.1 bits (74), Expect = 0.82 Identities = 17/51 (33%), Positives = 30/51 (58%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEV 475 GT+GY+APE+ N ++ D + G L+ EM++G P +Y+++V Sbjct: 347 GTVGYMAPEII--NHEKYTFSPDWWGLGCLIYEMIAGH---SPFRKYKEKV 392
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 33.1 bits (74), Expect = 0.82 Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 2/126 (1%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISG 436 +++PE S G + SD++SFG+++ E+ S L E Y+G+ + Sbjct: 1203 WMSPE--SLKDGVFTASSDMWSFGVVLWEITS----------------LAEQPYQGLSNE 1244 Query: 435 H--EWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 262 ++ + +LT + C Q+NPK RP+ ++VN+L L Sbjct: 1245 QVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSF 1304 Query: 261 FVSSEN 244 F S EN Sbjct: 1305 FYSEEN 1310
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 33.1 bits (74), Expect = 0.82 Identities = 25/59 (42%), Positives = 34/59 (57%), Gaps = 1/59 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTA-ARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 G+AK A D + +T T GT YIAPE + + SDVYS G++ E+VSG+R Sbjct: 161 GIAK--AVDAAPVTQTGMVMGTAQYIAPEQALGH--DATPASDVYSLGVIGYEVVSGKR 215
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 33.1 bits (74), Expect = 0.82 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 7/70 (10%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVE--YQDEVYL 469 GT YIAPE+ GVS D ++ G+L+ EM++G+ N D E D+V Sbjct: 539 GTPDYIAPEILQEMEYGVSV--DWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLY 596 Query: 468 PEWVYEGVIS 439 P W+ + ++ Sbjct: 597 PVWLSKEAVN 606
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 33.1 bits (74), Expect = 0.82 Identities = 26/59 (44%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTA-ARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 G+AK A D + +T T GT YIAPE + S SDVYS G++ E VSG+R Sbjct: 161 GIAK--AVDAAPVTQTGMVMGTAQYIAPEQALGH--DASPASDVYSLGVVGYEAVSGKR 215
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 33.1 bits (74), Expect = 0.82 Identities = 26/59 (44%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTA-ARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 G+AK A D + +T T GT YIAPE + S SDVYS G++ E VSG+R Sbjct: 161 GIAK--AVDAAPVTQTGMVMGTAQYIAPEQALGH--DASPASDVYSLGVVGYEAVSGKR 215
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 33.1 bits (74), Expect = 0.82 Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 2/126 (1%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISG 436 +++PE S G + SD++SFG+++ E+ S L E Y+G+ + Sbjct: 1192 WMSPE--SLKDGVFTASSDMWSFGVVLWEITS----------------LAEQPYQGLSNE 1233 Query: 435 H--EWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 262 ++ + +LT + C Q+NPK RP+ ++VN+L L Sbjct: 1234 QVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSF 1293 Query: 261 FVSSEN 244 F S EN Sbjct: 1294 FYSEEN 1299
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 33.1 bits (74), Expect = 0.82 Identities = 28/126 (22%), Positives = 61/126 (48%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 G+AK ++ +I A G++GY+APEV +++ G D++S G++ ++ G Sbjct: 194 GIAKQLKGEEDLIYKAA--GSLGYVAPEVLTQD--GHGKPCDIWSIGVITYTLLCG---Y 246 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + E ++ E + + +T M + + + L ++ NP +RP+ Sbjct: 247 SPFIAESVEGFMEE------CTASRYPVTFHMPYWDNISIDVKRFI-LKALRLNPADRPT 299 Query: 324 MTKVVN 307 T++++ Sbjct: 300 ATELLD 305
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 33.1 bits (74), Expect = 0.82 Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 1/137 (0%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGV-SYKSDVYSFGMLVLEMVSGRRN 508 GLA+ D + + AR + ++APE F G+ + KSDV+S+G+L+ E+ S N Sbjct: 831 GLARDIMSDSNYVVRGNARLPVKWMAPESL---FEGIYTIKSDVWSYGILLWEIFSLGVN 887 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P + Y + + G + T E + I+ C ++ + RP Sbjct: 888 PYPGIPVDANFY--KLIQNGFKMDQPFYATEE-----------IYIIMQSCWAFDSRKRP 934 Query: 327 SMTKVVNMLTGRLQNLQ 277 S + + L +L + + Sbjct: 935 SFPNLTSFLGCQLADAE 951
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 32.7 bits (73), Expect = 1.1 Identities = 25/108 (23%), Positives = 55/108 (50%), Gaps = 1/108 (0%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT YIAPE+ + G S++ D++S G+++ ++ G+ +QD+ + +Y Sbjct: 200 GTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGK------PPFQDKEV--KTIYRK 251 Query: 447 V-ISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 + + + + +++AE K+ + L + +P RPS+ +V+ Sbjct: 252 IKANSYSFPSNVDISAEAKDLISSL-------LTHDPSIRPSIDDIVD 292
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 32.7 bits (73), Expect = 1.1 Identities = 33/128 (25%), Positives = 55/128 (42%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 409 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVAKGRVP 465 Query: 504 DPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPS 325 P + ++ V E V G+ E M+ C + +P RP+ Sbjct: 466 YPGMVNRE-------VLEQVERGYRMPCPQRCPESLHELMK-------LCWKKDPDERPT 511 Query: 324 MTKVVNML 301 + + L Sbjct: 512 FEYIQSFL 519
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 32.7 bits (73), Expect = 1.1 Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSG 517 GLA + +R + G++ ++APEV ++ S++SDVYS+G+++ E+++G Sbjct: 488 GLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTG 544
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 32.7 bits (73), Expect = 1.1 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGV-SYKSDVYSFGMLVLEMVSGRRN 508 GLA+ D S + AR + ++APE F G+ + KSDV+S+G+L+ E+ S N Sbjct: 834 GLARDILSDSSYVVRGNARLPVKWMAPESL---FEGIYTIKSDVWSYGILLWEIFSLGVN 890 Query: 507 SDPSVEYQDEVY 472 P + Y Sbjct: 891 PYPGIPVDANFY 902
>MYLK_RABIT (P29294) Myosin light chain kinase, smooth muscle (EC 2.7.11.18)| (MLCK) [Contains: Telokin] Length = 1147 Score = 32.7 bits (73), Expect = 1.1 Identities = 18/52 (34%), Positives = 31/52 (59%) Frame = -3 Query: 672 LCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 L R ++ +L GT ++APEV N+ +SY +D++S G++ +VSG Sbjct: 840 LARRLENAGSLKVLFGTPEFVAPEVI--NYEPISYATDMWSIGVICYILVSG 889
>KCC1_YEAST (P27466) Calcium/calmodulin-dependent protein kinase I (EC| 2.7.11.17) Length = 446 Score = 32.7 bits (73), Expect = 1.1 Identities = 17/56 (30%), Positives = 33/56 (58%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 G+AK D+ ++ A G++GY+APEV +++ G D++S G++ ++ G Sbjct: 184 GIAKRLKSDEELLYKPA--GSLGYVAPEVLTQD--GHGKPCDIWSIGVITYTLLCG 235
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 32.7 bits (73), Expect = 1.1 Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 1/134 (0%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ +D + AR + ++APE ++ + + + +SDV+SFG+L+ E+ S + Sbjct: 1023 GLARDVYKDPDYVRKGDARLPLKWMAPEAIFDKIY---TTQSDVWSFGVLMWEIFSLGAS 1079 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P + +E + EG + M A E ++ L C P RP Sbjct: 1080 PYPGLHIDEEFCCR--LKEG----------TRMKAPEYSS-SEIYQTMLDCWHGEPSQRP 1126 Query: 327 SMTKVVNMLTGRLQ 286 + T++V L LQ Sbjct: 1127 TFTELVERLGDLLQ 1140
>YX05_CAEEL (Q11112) Putative tyrosine-protein kinase C03B1.5 in chromosome X| (EC 2.7.10.2) Length = 328 Score = 32.7 bits (73), Expect = 1.1 Identities = 20/65 (30%), Positives = 34/65 (52%) Frame = -3 Query: 666 ARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEY 487 +++QSI+ GT G+IAPE+ N G K+D++ G+L L ++ G ++ Sbjct: 186 SKNQSIL------GTPGFIAPEII--NLQGYDGKADLWGLGILSLFLLKGENPFKKCTQF 237 Query: 486 QDEVY 472 E Y Sbjct: 238 DLESY 242
>TTK_MOUSE (P35761) Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK)| (PYT) Length = 856 Score = 32.7 bits (73), Expect = 1.1 Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 9/158 (5%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVY---------SRNFGGVSYKSDVYSFGMLVL 532 G+A D + I + GT+ Y+APE S+ VS +SDV+S G ++ Sbjct: 665 GIANQMQPDTTSIVKDSQVGTVNYMAPEAIRDMSSSRENSKIRTKVSPRSDVWSLGCILY 724 Query: 531 EMVSGRRNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCI 352 M GR +Q + ++ + HE E E EK L V C+ Sbjct: 725 YMTYGR------TPFQHIINQVSKLHAIINPAHEIEF-----PEISEK--DLRDVLKCCL 771 Query: 351 QWNPKNRPSMTKVVNMLTGRLQNLQIPPKPFVSSENHP 238 NPK R S+ +++ P+V + HP Sbjct: 772 VRNPKERISIPELLT-------------HPYVQIQPHP 796
>STLK_DROME (P83098) Putative serine/threonine-protein kinase STE20-like (EC| 2.7.11.1) Length = 346 Score = 32.7 bits (73), Expect = 1.1 Identities = 14/33 (42%), Positives = 20/33 (60%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 + APEV +N G + K D+YS G+ EM +G Sbjct: 179 WTAPEVLYQNLSGYTEKIDIYSIGITCCEMANG 211
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 32.7 bits (73), Expect = 1.1 Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSG 517 GLA + +R + G++ ++APEV ++ S++SDVYS+G+++ E+++G Sbjct: 221 GLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTG 277
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 32.7 bits (73), Expect = 1.1 Identities = 39/145 (26%), Positives = 69/145 (47%), Gaps = 2/145 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ ++ + R + ++APE ++ + + S KSDV+S+G+L+ E+ S + Sbjct: 1042 GLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIY---STKSDVWSYGVLLWEIFSLGGS 1098 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ DE + + EG+ M A E ++ + L C +PK RP Sbjct: 1099 PYPGVQ-MDEDFCSR-LREGM----------RMRAPE-YSTPEIYQIMLDCWHRDPKERP 1145 Query: 327 SMTKVVNMLTGRLQ-NLQIPPKPFV 256 ++V L LQ N+Q K ++ Sbjct: 1146 RFAELVEKLGDLLQANVQQDGKDYI 1170
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 32.7 bits (73), Expect = 1.1 Identities = 18/57 (31%), Positives = 33/57 (57%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 G+AK + + +I T G+ Y++PE V ++D+YSFG+++ EM +G+ Sbjct: 153 GIAK-ASNESTITTTNKVVGSAHYLSPE--QAQGIPVDCRTDIYSFGIVLYEMATGK 206
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 32.7 bits (73), Expect = 1.1 Identities = 27/107 (25%), Positives = 52/107 (48%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT YIAPEV S+ G S++ DV+S G ++ ++ G+ + S E YL Sbjct: 213 GTPNYIAPEVLSKK--GHSFEVDVWSIGCIMYTLLVGKPPFETSC--LKETYLR------ 262 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 I +E+ + + ++++ +Q +P RP++ +++N Sbjct: 263 -IKKNEYSIPKHINPVAASLIQKM-------LQTDPAARPTIHELLN 301
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 32.7 bits (73), Expect = 1.1 Identities = 27/107 (25%), Positives = 52/107 (48%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT YIAPEV S+ G S++ DV+S G ++ ++ G+ + S E YL Sbjct: 213 GTPNYIAPEVLSKK--GHSFEVDVWSIGCIMYTLLVGKPPFETSC--LKETYLR------ 262 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 I +E+ + + ++++ +Q +P RP++ +++N Sbjct: 263 -IKKNEYSIPKHINPVAASLIQKM-------LQTDPTARPTIHELLN 301
>GRK4_HUMAN (P32298) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) (ITI1) Length = 578 Score = 32.7 bits (73), Expect = 1.1 Identities = 18/51 (35%), Positives = 29/51 (56%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEV 475 GT+GY+APEV N ++ D + G L+ EM+ G P +Y+++V Sbjct: 348 GTVGYMAPEVV--NNEKYTFSPDWWGLGCLIYEMIQGH---SPFKKYKEKV 393
>ST32C_HUMAN (Q86UX6) Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE)| (YANK3) Length = 486 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 14/79 (17%) Frame = -3 Query: 639 TAARGTMGYIAPEVYSR--NFG-GVSYKSDVYSFGMLVLEMVSGRR----NSDPSVEYQD 481 TA GT Y+APE++ N G G S++ D +S G++ E++ G R +S +VE Sbjct: 248 TALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLV 307 Query: 480 EV-------YLPEWVYEGV 445 ++ Y+P W E V Sbjct: 308 QLFSTVSVQYVPTWSKEMV 326
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 32.3 bits (72), Expect = 1.4 Identities = 22/64 (34%), Positives = 35/64 (54%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 413 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 469 Query: 504 DPSV 493 P + Sbjct: 470 YPGM 473
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/39 (46%), Positives = 25/39 (64%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 GT Y++PE + V+ SDVYS G++ EM+SGRR Sbjct: 186 GTAQYVSPEQAQGH--QVTPASDVYSLGVVGYEMLSGRR 222
>GCY3E_DROME (Q07553) Guanylate cyclase 32E precursor (EC 4.6.1.2)| Length = 1163 Score = 32.3 bits (72), Expect = 1.4 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 7/63 (11%) Frame = -3 Query: 612 IAPEVYSRNF--GGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDE-----VYLPEWVY 454 +APE+ + G S K DVYSFG+L+ EM+ GR+ Y E V PE + Sbjct: 696 MAPELLRDAYRPGRGSQKGDVYSFGILLYEMI-GRKGPWGDTAYSKEEIIQFVKCPEMLQ 754 Query: 453 EGV 445 GV Sbjct: 755 HGV 757
>AL2S2_MOUSE (Q8K4T3) Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase) Length = 418 Score = 32.3 bits (72), Expect = 1.4 Identities = 12/34 (35%), Positives = 23/34 (67%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 +++PE+ ++ G + KSD+YS G+ E+ SG+ Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>AL2S2_HUMAN (Q9C0K7) Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP-interacting protein) (CALS-21) Length = 418 Score = 32.3 bits (72), Expect = 1.4 Identities = 12/34 (35%), Positives = 23/34 (67%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 +++PE+ ++ G + KSD+YS G+ E+ SG+ Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 32.3 bits (72), Expect = 1.4 Identities = 28/99 (28%), Positives = 46/99 (46%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ +Y Sbjct: 335 GTPEFMAPEMYEEKYDEAV---DVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 384 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNR 331 V SG ++ + K KM ++ + CI+ + R Sbjct: 385 VTSG------TKPNSFYKVKMPEVKEIIEGCIRTDKNER 417
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 32.3 bits (72), Expect = 1.4 Identities = 28/99 (28%), Positives = 46/99 (46%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ +Y Sbjct: 335 GTPEFMAPEMYEEKYDEAV---DVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 384 Query: 447 VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNR 331 V SG ++ + K KM ++ + CI+ + R Sbjct: 385 VTSG------TKPNSFYKVKMPEVKEIIEGCIRTDKNER 417
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Frame = -3 Query: 627 GTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 511 GT Y+APE + G DV+S G +VLEM++GRR Sbjct: 1459 GTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRR 1498
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSG 517 GLA + +R + G++ ++APEV ++ S++SDVYS+G+++ E+++G Sbjct: 163 GLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAG 219
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 32.3 bits (72), Expect = 1.4 Identities = 22/64 (34%), Positives = 35/64 (54%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R Sbjct: 406 GLARLI-EDNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVP 462 Query: 504 DPSV 493 P + Sbjct: 463 YPGM 466
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLA + +R G++ ++APEV ++ S++SDVY+FG+++ E+++G+ Sbjct: 222 GLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 279
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 32.3 bits (72), Expect = 1.4 Identities = 16/37 (43%), Positives = 24/37 (64%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT Y+APE+ SR VS SD+++F +V +M+ G Sbjct: 222 GTAEYVAPELLSRQV--VSKSSDLWAFACVVYQMIVG 256
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 32.3 bits (72), Expect = 1.4 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 2/128 (1%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISG 436 +++PE S G + SDV+SFG+++ E+ + L E Y+G+ + Sbjct: 1174 WMSPE--SLKDGVFTTNSDVWSFGVVLWEIAT----------------LAEQPYQGMSNE 1215 Query: 435 HEWELTSEMTAEEKEKMRQLTIVALW--CIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 262 E EK + L C Q+NPK RPS ++++ + L Sbjct: 1216 QVLRFVMEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIISSIKDELDPGFKEVSF 1275 Query: 261 FVSSENHP 238 F S EN P Sbjct: 1276 FYSEENKP 1283
>SKM1_YEAST (Q12469) Serine/threonine-protein kinase SKM1 (EC 2.7.11.1)| (Protein kinase 75490 D) Length = 655 Score = 32.3 bits (72), Expect = 1.4 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 3/46 (6%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR---RNSDP 499 GT ++APE+ ++ G K DV+S G++++EM+ G N DP Sbjct: 544 GTPYWMAPEIVNQK--GYDEKVDVWSLGIMLIEMIEGEPPYLNEDP 587
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 4/40 (10%) Frame = -3 Query: 627 GTMGYIAPEVY-SRNF---GGVSYKSDVYSFGMLVLEMVS 520 GTMGY+APEV S+N GG K D++S G ++ M++ Sbjct: 331 GTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLT 370
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 32.3 bits (72), Expect = 1.4 Identities = 31/124 (25%), Positives = 51/124 (41%) Frame = -3 Query: 642 LTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPE 463 L ++R + + APE G + KSDV+SFG+L+ E+ S R P + ++ Sbjct: 381 LDSSRLPVKWTAPEALKH--GKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKE------ 432 Query: 462 WVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQN 283 V E V G+ E + ++ C + P RP K+ L L++ Sbjct: 433 -VSEAVEKGYRMEPPEGCPG-------PVHVLMSSCWEAEPARRPPFRKLAEKLARELRS 484 Query: 282 LQIP 271 P Sbjct: 485 AGAP 488
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/47 (38%), Positives = 28/47 (59%) Frame = -3 Query: 660 DQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVS 520 D + T + + + +PEV+S F S KSDV+SFG+L+ E+ S Sbjct: 514 DDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFS 558
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLA + +R G++ ++APEV ++ S++SDVY+FG+++ E+++G+ Sbjct: 596 GLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 653
>ST32C_MOUSE (Q8QZV4) Serine/threonine-protein kinase 32C (EC 2.7.11.1)| Length = 488 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 14/79 (17%) Frame = -3 Query: 639 TAARGTMGYIAPEVYSR--NFG-GVSYKSDVYSFGMLVLEMVSGRR----NSDPSVEYQD 481 TA GT Y+APE++ N G G S++ D +S G++ E++ G R +S +VE Sbjct: 249 TALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLV 308 Query: 480 EV-------YLPEWVYEGV 445 ++ Y+P W E V Sbjct: 309 QLFSTVSVQYVPTWSKEMV 327
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLA + +R G++ ++APEV ++ S++SDVY+FG+++ E+++G+ Sbjct: 206 GLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 263
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/109 (23%), Positives = 57/109 (52%), Gaps = 2/109 (1%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRR--NSDPSVEYQDEVYLPEWVY 454 GT YI+PE+ +R+ G+ +SD++S G + ++ GR ++D ++V L Sbjct: 173 GTPNYISPEIATRSAHGL--ESDIWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLA---- 226 Query: 453 EGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKVVN 307 ++E+ + ++ E ++ + QL ++ NP +R S++ V++ Sbjct: 227 -------DYEMPAFLSREAQDLIHQL-------LRRNPADRLSLSSVLD 261
>PKN2_CLOPE (Q8XJL8) Probable serine/threonine protein kinase CPE1738 (EC| 2.7.11.1) Length = 685 Score = 32.3 bits (72), Expect = 1.4 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLT-AARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 G+AK + D S I T + G+ Y +PE + Y++D+YS G+++ EMV+G Sbjct: 153 GIAK--SMDSSTIAHTNSVMGSAHYFSPEQAKGTY--TDYRTDLYSLGIVLYEMVTG 205
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 32.3 bits (72), Expect = 1.4 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 3/136 (2%) Frame = -3 Query: 663 RDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLE-MVSGRRNSDPSVEY 487 R +++ T + R + APE FG S SDV+SFG+++ E M G R Sbjct: 796 RSEAVYTTMSGRSPALWAAPETLQ--FGHFSSASDVWSFGIIMWEVMAFGER-------- 845 Query: 486 QDEVYLPEWVYEG--VISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKV 313 P W G VI E + L + L C Q +P RP +++ Sbjct: 846 ------PYWDMSGQDVIKAVE---DGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQI 896 Query: 312 VNMLTGRLQNLQIPPK 265 ++L+ +Q+ + PPK Sbjct: 897 HSILSKMVQDPE-PPK 911
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 32.3 bits (72), Expect = 1.4 Identities = 21/64 (32%), Positives = 36/64 (56%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA++ D A+ + + APE +FG + K+DV+SFG+L++E+V+ R Sbjct: 379 GLARII--DSEYTAQEGAKFPIKWTAPEAI--HFGVFTIKADVWSFGVLLMEVVTYGRVP 434 Query: 504 DPSV 493 P + Sbjct: 435 YPGM 438
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSG 517 GLA + +R + G++ ++APEV ++ S++SDVYS+G+++ E+++G Sbjct: 488 GLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTG 544
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSG 517 GLA + +R + G++ ++APEV ++ S++SDVYS+G+++ E+++G Sbjct: 488 GLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAG 544
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/57 (31%), Positives = 36/57 (63%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSG 517 GLA + +R + G++ ++APEV ++ S++SDVYS+G+++ E+++G Sbjct: 488 GLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTG 544
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLA + +R G++ ++APEV ++ S++SDVY+FG+++ E+++G+ Sbjct: 158 GLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 215
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 32.3 bits (72), Expect = 1.4 Identities = 29/108 (26%), Positives = 51/108 (47%) Frame = -3 Query: 636 AARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWV 457 A G+ ++APEV + K+DV+S+G+++ E+++ R +DP YLP Sbjct: 215 AVVGSPFWMAPEVLRDE--PYNEKADVFSYGIILCEIIA-RIQADPD-------YLPRTE 264 Query: 456 YEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRPSMTKV 313 G+ +++ M + QLT C +PK RPS ++ Sbjct: 265 NFGL----DYDAFQNMVGDCPSDFLQLTFN---CCNMDPKLRPSFEEI 305
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLA + +R G++ ++APEV ++ S++SDVY+FG+++ E+++G+ Sbjct: 636 GLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 693
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/58 (31%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSGR 514 GLA + +R G++ ++APEV ++ S++SDVY+FG+++ E+++G+ Sbjct: 636 GLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 693
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 32.0 bits (71), Expect = 1.8 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 GT ++APE+ SR G K DV+S G++++EM+ G Sbjct: 1110 GTPYWMAPEIVSRKEYGP--KVDVWSLGIMIIEMLEG 1144
>MPH1_SCHPO (O94235) Serine/threonine-protein kinase mph1 (EC 2.7.12.2)| Length = 678 Score = 32.0 bits (71), Expect = 1.8 Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 9/66 (13%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-----RNFGGVSYK----SDVYSFGMLVL 532 G+AK D + I + GT+ Y+APE + N G K SDV+S G ++ Sbjct: 461 GIAKAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILY 520 Query: 531 EMVSGR 514 +MV GR Sbjct: 521 QMVYGR 526
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 32.0 bits (71), Expect = 1.8 Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 3/116 (2%) Frame = -3 Query: 639 TAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPE 463 T R + ++APE ++ R + +++SDV+SFG+L+ E+ + + +P V ++ Sbjct: 658 TNGRLPVKWMAPEALFDRIY---THQSDVWSFGVLLWEIFTLGGSPNPGVPVEE------ 708 Query: 462 WVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWN--PKNRPSMTKVVNML 301 +++ + GH + S T E MR WN P RP+ ++V L Sbjct: 709 -LFKLLKEGHRMDKPSNCTNELYMMMRDC---------WNAVPSQRPTFKQLVEDL 754
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 32.0 bits (71), Expect = 1.8 Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -3 Query: 573 SYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDE---VYLPEWVYEGVISGHEWELTSEMTA 403 S K DVYSFG++ E++ RR + ++ +D+ ++ E + + +L E TA Sbjct: 661 SQKGDVYSFGIIAQEIIM-RRETFYTLSCRDQKEKIFRVE--HPDGLKPFRPDLFLE-TA 716 Query: 402 EEKEKMRQLTIVALWCIQWNPKNRPSMTKVVNML 301 EEKE ++ ++ C + +P+ RP K+ N L Sbjct: 717 EEKE--LEVFLLVKNCWEEDPEKRPDFKKIENTL 748
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 32.0 bits (71), Expect = 1.8 Identities = 22/64 (34%), Positives = 34/64 (53%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNS 505 GLA+L D AR + + APE + +G + KSDV+SFG+L+ E+ + R Sbjct: 402 GLARLI-EDNEYTARPGARFPVKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVP 458 Query: 504 DPSV 493 P + Sbjct: 459 YPGM 462
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 32.0 bits (71), Expect = 1.8 Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Frame = -3 Query: 645 TLTAARGTMGYIAPEVYSRN-FGGVSYKSDVYSFGMLVLEMVSGRR 511 +L GT Y+APE S + G DV++ G +VLEM +GRR Sbjct: 1205 SLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRR 1250
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 32.0 bits (71), Expect = 1.8 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 11/112 (9%) Frame = -3 Query: 666 ARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR---RNSDP- 499 AR+ +A GT ++ PEV S S SDV+S+G+L+ E+++G + DP Sbjct: 294 AREMYNTQRMSAAGTYAWMPPEVIS--VSTYSKFSDVWSYGVLLWELITGETPYKGFDPL 351 Query: 498 SVEYQDEVY-----LPEWVYE--GVISGHEWELTSEMTAEEKEKMRQLTIVA 364 SV Y V +P+ E G + W+ KE ++QL +A Sbjct: 352 SVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIA 403
>BMR1A_MOUSE (P36895) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) Length = 532 Score = 32.0 bits (71), Expect = 1.8 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 4/63 (6%) Frame = -3 Query: 648 ITLTAARGTMGYIAPEVYSRNFGGVSYK----SDVYSFGMLVLEMVSGRRNSDPSVEYQD 481 I L GT Y+APEV + ++ +D+YSFG+++ EM EYQ Sbjct: 396 IPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQL 455 Query: 480 EVY 472 Y Sbjct: 456 PYY 458
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 32.0 bits (71), Expect = 1.8 Identities = 25/102 (24%), Positives = 48/102 (47%) Frame = -3 Query: 567 KSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEK 388 KSDV+SFG+ + E+ + + P VE + +Y+ + G+ + + + Sbjct: 722 KSDVWSFGVTMWEIATRGQTPYPGVENSE-------IYDYLRQGNRLK-------QPADC 767 Query: 387 MRQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 262 + L + C + NP++RPS T++ L L+ L +P Sbjct: 768 LDGLYALMSRCWELNPQDRPSFTELREDLENTLKALPPAQEP 809
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 32.0 bits (71), Expect = 1.8 Identities = 17/50 (34%), Positives = 30/50 (60%) Frame = -3 Query: 666 ARDQSIITLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSG 517 AR+ T + GT ++APEV + S SD++S+G+L+ E+++G Sbjct: 293 AREWHRTTKMSTAGTYAWMAPEVIKSSL--FSKGSDIWSYGVLLWELLTG 340
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 32.0 bits (71), Expect = 1.8 Identities = 15/38 (39%), Positives = 22/38 (57%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 GT+GY+APE+ SY D + G L+ EM+ G+ Sbjct: 364 GTVGYMAPEIVKNE--RYSYGVDWWGVGCLIYEMIEGK 399
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 32.0 bits (71), Expect = 1.8 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 7/70 (10%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVE-------YQDEVYL 469 GT YIAPE+ G S D ++ G+L+ EM++G+ + E D+V Sbjct: 464 GTPDYIAPEILKEQEYGASV--DWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLY 521 Query: 468 PEWVYEGVIS 439 P W+ +S Sbjct: 522 PVWLSREAVS 531
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 32.0 bits (71), Expect = 1.8 Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 2/111 (1%) Frame = -3 Query: 564 SDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKM 385 SDV+SFG+++ E+ S L E Y+G+ + + + + + + Sbjct: 1206 SDVWSFGVVLWEITS----------------LAEQPYQGLSNEQVLKFVMDGGSLDHPEN 1249 Query: 384 --RQLTIVALWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKPFVSSENHP 238 +L + C Q+NPK RP+ ++++ML L+ + S EN P Sbjct: 1250 CPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLRPSFQDVSFYYSDENKP 1300
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 32.0 bits (71), Expect = 1.8 Identities = 18/57 (31%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPEVYS-RNFGGVSYKSDVYSFGMLVLEMVSG 517 GLA + R + G++ ++APEV ++ S++SDVYS+G+++ E+++G Sbjct: 479 GLATVKTRWSGSQQVEQLTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTG 535
>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7.11.1)| (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2) Length = 2297 Score = 32.0 bits (71), Expect = 1.8 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVS 520 GT ++APE+Y ++ DVY+FGM +LEM + Sbjct: 359 GTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMAT 391
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 31.6 bits (70), Expect = 2.4 Identities = 22/66 (33%), Positives = 33/66 (50%) Frame = -3 Query: 627 GTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEYQDEVYLPEWVYEG 448 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ +Y Sbjct: 338 GTPEFMAPEMYEEKYDEAV---DVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 387 Query: 447 VISGHE 430 V SG + Sbjct: 388 VTSGRK 393
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 31.6 bits (70), Expect = 2.4 Identities = 18/32 (56%), Positives = 22/32 (68%) Frame = -3 Query: 615 YIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVS 520 + APE SR G S KSDV+SFG+L+ EM S Sbjct: 353 WTAPEALSR--GHYSTKSDVWSFGILLHEMFS 382
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 31.6 bits (70), Expect = 2.4 Identities = 15/44 (34%), Positives = 26/44 (59%) Frame = -3 Query: 645 TLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 T+ GT+GY+APEV ++ D ++ G L+ EM++G+ Sbjct: 341 TIKGRVGTVGYMAPEVVKNE--RYTFSPDWWALGCLLYEMIAGQ 382
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 31.6 bits (70), Expect = 2.4 Identities = 15/44 (34%), Positives = 26/44 (59%) Frame = -3 Query: 645 TLTAARGTMGYIAPEVYSRNFGGVSYKSDVYSFGMLVLEMVSGR 514 T+ GT+GY+APEV ++ D ++ G L+ EM++G+ Sbjct: 341 TIKGRVGTVGYMAPEVVKNE--RYTFSPDWWALGCLLYEMIAGQ 382
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 31.6 bits (70), Expect = 2.4 Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 2/145 (1%) Frame = -3 Query: 684 GLAKLCARDQSIITLTAARGTMGYIAPE-VYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN 508 GLA+ ++ + R + ++APE ++ + + S KSDV+S+G+L+ E+ S + Sbjct: 1042 GLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVY---STKSDVWSYGVLLWEIFSLGGS 1098 Query: 507 SDPSVEYQDEVYLPEWVYEGVISGHEWELTSEMTAEEKEKMRQLTIVALWCIQWNPKNRP 328 P V+ DE + + EG+ T E E + + L C +PK RP Sbjct: 1099 PYPGVQ-MDEDFCSR-LKEGMRM-----RTPEYATPE------IYQIMLDCWHKDPKERP 1145 Query: 327 SMTKVVNMLTGRLQ-NLQIPPKPFV 256 ++V L LQ N+Q K ++ Sbjct: 1146 RFAELVEKLGDLLQANVQQDGKDYI 1170 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 102,376,344 Number of Sequences: 219361 Number of extensions: 2144191 Number of successful extensions: 6225 Number of sequences better than 10.0: 391 Number of HSP's better than 10.0 without gapping: 5918 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6135 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6825954960 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
