ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbaal37h03
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 248 1e-65
2IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast... 248 1e-65
3IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 241 1e-63
4IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 238 8e-63
5IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic ... 204 2e-52
6IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic ... 204 2e-52
7IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (E... 202 5e-52
8IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial... 202 9e-52
9IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic ... 202 9e-52
10IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondri... 202 9e-52
11IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondri... 201 1e-51
12IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic ... 200 3e-51
13IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondri... 186 5e-47
14IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 186 6e-47
15IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 186 6e-47
16IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondri... 179 6e-45
17IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic ... 177 2e-44
18IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 177 2e-44
19IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 177 3e-44
20IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal ... 176 7e-44
21IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mi... 169 6e-42
22IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondri... 168 1e-41
23IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondri... 158 1e-38
24LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 42 0.002
25LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 41 0.003
26LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 41 0.003
27LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 40 0.004
28LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 40 0.004
29IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,... 40 0.004
30IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alph... 40 0.004
31IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alph... 40 0.008
32LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.022
33LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.022
34LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.029
35LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.029
36LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.064
37LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.064
38LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.064
39LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.083
40LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.083
41LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.083
42LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
43LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
44LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
45LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.14
46LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.14
47LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.19
48LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
49LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
50LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
51LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
52LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
53LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
54LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
55LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.32
56LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.32
57LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.41
58LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.41
59LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.41
60LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.41
61LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.41
62LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.41
63LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.70
64LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.70
65LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.70
66LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.70
67LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
68LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
69LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
70IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] sub... 33 0.92
71LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
72LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
73LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
74LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
75LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
76LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
77LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
78LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
79LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
80LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
81LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
82LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
83LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
84LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
85LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.92
86LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
87LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
88LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
89LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
90LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.2
91LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.6
92LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.6
93LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.6
94LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.6
95ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1) 32 1.6
96IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 32 2.0
97LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
98LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
99LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
100LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
101LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
102LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.7
103LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.7
104LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 2.7
105LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.5
106LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.5
107LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.5
108LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.5
109LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.5
110LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.5
111LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.5
112LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.6
113LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast... 30 4.6
114LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.6
115LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.6
116LEU3_BUCUL (Q9AQC8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.6
117LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.6
118INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin bet... 30 4.6
119LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 4.6
120Y1185_METJA (Q58585) Hypothetical protein MJ1185 30 6.0
121LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 6.0
122LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 6.0
123LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 6.0
124LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 6.0
125LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 6.0
126LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.8
127SYNJ1_BOVIN (O18964) Synaptojanin-1 (EC 3.1.3.36) (Synaptic inos... 30 7.8 
>IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 413

 Score =  248 bits (632), Expect = 1e-65
 Identities = 121/137 (88%), Positives = 131/137 (95%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRHFRVHQKGGETST
Sbjct: 271 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 330

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           NSIASIFAWTRGLAHRAKLDDNA+LL+F +KLE AC+G VE+GKMTKDLAL++HG SK++
Sbjct: 331 NSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAACIGVVEAGKMTKDLALILHG-SKLS 389

Query: 271 RSDYLNTEEFIDAVAAE 221
           R  YLNTEEFIDAVAAE
Sbjct: 390 REHYLNTEEFIDAVAAE 406
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>IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast precursor (EC|
           1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (Fragment)
          Length = 433

 Score =  248 bits (632), Expect = 1e-65
 Identities = 122/137 (89%), Positives = 130/137 (94%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRHFRVHQKGGETST
Sbjct: 291 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 350

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           NSIASIFAWTRGLAHRAKLDDNA LL+F +KLE AC+G VESGKMTKDLAL++HG SK++
Sbjct: 351 NSIASIFAWTRGLAHRAKLDDNATLLDFTEKLEAACIGVVESGKMTKDLALILHG-SKLS 409

Query: 271 RSDYLNTEEFIDAVAAE 221
           R  YLNTEEFIDAVAAE
Sbjct: 410 REHYLNTEEFIDAVAAE 426
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>IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 415

 Score =  241 bits (615), Expect = 1e-63
 Identities = 118/137 (86%), Positives = 128/137 (93%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+RVHQKGGETST
Sbjct: 270 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETST 329

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           NSIASIFAWTRGLAHRA LD+N RLL+F +KLE AC+G VESGKMTKDLAL++HG SK++
Sbjct: 330 NSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAVESGKMTKDLALIIHG-SKLS 388

Query: 271 RSDYLNTEEFIDAVAAE 221
           R  YLNTEEFIDAVA E
Sbjct: 389 RDHYLNTEEFIDAVADE 405
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>IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 416

 Score =  238 bits (608), Expect = 8e-63
 Identities = 116/137 (84%), Positives = 126/137 (91%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSDFLAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+RVHQKGGETST
Sbjct: 270 ACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETST 329

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           NSIASIFAWTRGLAHRA LD+N RLL+F +KLE AC+G VESGKMTKDLAL++   SK++
Sbjct: 330 NSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAVESGKMTKDLALIIIHGSKLS 389

Query: 271 RSDYLNTEEFIDAVAAE 221
           R  YLNTEEFIDAVA E
Sbjct: 390 REHYLNTEEFIDAVADE 406
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>IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  204 bits (519), Expect = 2e-52
 Identities = 97/132 (73%), Positives = 113/132 (85%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R+HQKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETST 327

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAW+RGLAHRA+LD+N  L  FA+ LEE C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 271 RSDYLNTEEFID 236
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  204 bits (519), Expect = 2e-52
 Identities = 97/132 (73%), Positives = 113/132 (85%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R+HQKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETST 327

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAW+RGLAHRA+LD+N  L  FA+ LEE C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 271 RSDYLNTEEFID 236
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  202 bits (515), Expect = 5e-52
 Identities = 97/132 (73%), Positives = 112/132 (84%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAW+RGLAHRAKLD+N  L  FA  LEE C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 271 RSDYLNTEEFID 236
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M) (Fragment)
          Length = 421

 Score =  202 bits (513), Expect = 9e-52
 Identities = 100/135 (74%), Positives = 111/135 (82%), Gaps = 1/135 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 276 ACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 335

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAWTRGL HR KLD N  L+ FAQ LE+ CV TVESG MTKDLA  +HG S V 
Sbjct: 336 NPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVK 395

Query: 271 RSD-YLNTEEFIDAV 230
            ++ +LNT +F+D +
Sbjct: 396 LNEHFLNTSDFLDTI 410
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>IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  202 bits (513), Expect = 9e-52
 Identities = 96/132 (72%), Positives = 113/132 (85%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAW+RGLAHRAKLD+N  L  FA+ LE+ C+ T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 271 RSDYLNTEEFID 236
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  202 bits (513), Expect = 9e-52
 Identities = 100/135 (74%), Positives = 111/135 (82%), Gaps = 1/135 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 307 ACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 366

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAWTRGL HR KLD N  L+ FAQ LE+ CV TVESG MTKDLA  +HG S V 
Sbjct: 367 NPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVK 426

Query: 271 RSD-YLNTEEFIDAV 230
            ++ +LNT +F+D +
Sbjct: 427 LNEHFLNTSDFLDTI 441
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>IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  201 bits (512), Expect = 1e-51
 Identities = 100/135 (74%), Positives = 111/135 (82%), Gaps = 1/135 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 307 ACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 366

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAWTRGL HR KLD N  L+ FAQ LE+ CV TVESG MTKDLA  +HG S V 
Sbjct: 367 NPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVK 426

Query: 271 RSD-YLNTEEFIDAV 230
            ++ +LNT +F+D +
Sbjct: 427 LNEHFLNTTDFLDTI 441
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>IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  200 bits (509), Expect = 3e-51
 Identities = 97/132 (73%), Positives = 111/132 (84%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQG+GSLG+MTSVL+CPDGKT+EAEAAHGTVTRH+R++QKG ETST
Sbjct: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAWTRGLAHRAKLD+N  L  FA  LEE  + T+E+G MTKDLA  + G   V 
Sbjct: 328 NPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQ 387

Query: 271 RSDYLNTEEFID 236
           RSDYLNT EF+D
Sbjct: 388 RSDYLNTFEFMD 399
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>IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 523

 Score =  186 bits (472), Expect = 5e-47
 Identities = 95/135 (70%), Positives = 106/135 (78%), Gaps = 1/135 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD LA  FGSLGLMTSVL+CPDGKTIEAEAAHGTVTRH+R HQKG  TST
Sbjct: 379 ACKNYDGDVQSDILASRFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTST 438

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
             IASIFAWTRGL HR KLD N  L+ FAQ  E+ CV TVE G MTKDLA  +HG S V 
Sbjct: 439 KGIASIFAWTRGLEHRGKLDGNQDLIRFAQTREKVCVQTVE-GAMTKDLAGCIHGLSNVK 497

Query: 271 RSD-YLNTEEFIDAV 230
            ++ +LNT +F+D +
Sbjct: 498 LNEHFLNTTDFLDTI 512
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>IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 409

 Score =  186 bits (471), Expect = 6e-47
 Identities = 92/135 (68%), Positives = 107/135 (79%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQG+GSLGLMTSVLM  DGKT+EAEAAHGTVTRH+R +Q G  TST
Sbjct: 271 ACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTST 330

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAWTRGL HR KLD    +++FA KLE   + TVESGKMTKDLA+L+       
Sbjct: 331 NPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIG-----P 385

Query: 271 RSDYLNTEEFIDAVA 227
             D+LN+EEF+DA+A
Sbjct: 386 EQDWLNSEEFLDAIA 400
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>IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 409

 Score =  186 bits (471), Expect = 6e-47
 Identities = 92/135 (68%), Positives = 107/135 (79%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQG+GSLGLMTSVLM  DGKT+EAEAAHGTVTRH+R +Q G  TST
Sbjct: 271 ACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTST 330

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAWTRGL HR KLD    +++FA KLE   + TVESGKMTKDLA+L+       
Sbjct: 331 NPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIG-----P 385

Query: 271 RSDYLNTEEFIDAVA 227
             D+LN+EEF+DA+A
Sbjct: 386 EQDWLNSEEFLDAIA 400
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>IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (CtIDP1)
          Length = 430

 Score =  179 bits (454), Expect = 6e-45
 Identities = 94/136 (69%), Positives = 107/136 (78%), Gaps = 1/136 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A KNYDGDVQSD +AQGFGSLGLMTS LM PDGK  EAEAAHGTVTRH+R HQ+G ETST
Sbjct: 293 ALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDGKAYEAEAAHGTVTRHYRQHQQGKETST 352

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKV 275
           NSIASIFAWTRGLA R KLD+   +++FA KLE+A + TVE  + MTKDLAL +    K 
Sbjct: 353 NSIASIFAWTRGLAQRGKLDETPDVVDFASKLEQATIDTVEVDRIMTKDLALAM---GKT 409

Query: 274 TRSDYLNTEEFIDAVA 227
            RS Y+ T EF+DAVA
Sbjct: 410 DRSAYVTTTEFLDAVA 425
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>IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 412

 Score =  177 bits (450), Expect = 2e-44
 Identities = 94/135 (69%), Positives = 107/135 (79%), Gaps = 1/135 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A KNYDGDV+SD +AQGFGSLGLMTSVL+ PDGKT E+EAAHGTVTRHFR HQ+G ETST
Sbjct: 268 AMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHFRQHQQGKETST 327

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKV 275
           NSIASIFAWTRG+  R KLD+   +++F Q LE A V TV E G MTKDLAL++    K 
Sbjct: 328 NSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQEDGIMTKDLALIL---GKS 384

Query: 274 TRSDYLNTEEFIDAV 230
            RS Y+ TEEFIDAV
Sbjct: 385 ERSAYVTTEEFIDAV 399
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>IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 420

 Score =  177 bits (449), Expect = 2e-44
 Identities = 91/136 (66%), Positives = 107/136 (78%), Gaps = 1/136 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT E+EAAHGTVTRHFR HQ+G ETST
Sbjct: 268 AMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFESEAAHGTVTRHFRKHQRGEETST 327

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVE-SGKMTKDLALLVHGSSKV 275
           NSIASIFAWTR +  R KLD+   +++F   LE+A + TV+  GKMTKDLAL++    K 
Sbjct: 328 NSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKATLDTVQVGGKMTKDLALML---GKT 384

Query: 274 TRSDYLNTEEFIDAVA 227
            RS Y+ TEEFID VA
Sbjct: 385 NRSSYVTTEEFIDEVA 400
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>IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 406

 Score =  177 bits (448), Expect = 3e-44
 Identities = 86/134 (64%), Positives = 105/134 (78%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDVQSD +AQGFGSLGLMTSVL+ PDGKT+EAEAAHGTVTRH+R HQ+G  TST
Sbjct: 266 ACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDGKTVEAEAAHGTVTRHYRQHQQGKATST 325

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IASIFAWT+GL+ R K DD   +++FA+ LE+ C+ TVE G MTKDLALL+       
Sbjct: 326 NPIASIFAWTQGLSFRGKFDDTPDVVKFAETLEQVCIKTVEGGAMTKDLALLIGPDQA-- 383

Query: 271 RSDYLNTEEFIDAV 230
              ++ TE+F +A+
Sbjct: 384 ---WMTTEQFFEAI 394
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>IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (PS-NADP-IDH)
           (CtIDP2)
          Length = 410

 Score =  176 bits (445), Expect = 7e-44
 Identities = 91/136 (66%), Positives = 105/136 (77%), Gaps = 1/136 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A KNYDGDVQSD +AQGFGSLGLMTSVL+ PDGK  E+EAAHGTVTRH+R HQ+G ETST
Sbjct: 269 AMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKAFESEAAHGTVTRHYRQHQQGKETST 328

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKV 275
           NSIASI+AWTRGL  R KLDD   +++FA++LE+A + TV     MTKDLAL      K 
Sbjct: 329 NSIASIYAWTRGLIQRGKLDDTPEVVKFAEELEKAVIETVSKDNIMTKDLALT---QGKT 385

Query: 274 TRSDYLNTEEFIDAVA 227
            RS Y+ TEEFID VA
Sbjct: 386 DRSSYVTTEEFIDGVA 401
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>IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mitochondrial|
           precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase)
           (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 418

 Score =  169 bits (428), Expect = 6e-42
 Identities = 87/137 (63%), Positives = 105/137 (76%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           ACKNYDGDV SD +AQ +GSLGLMTSVL+ P+G+T E+EAAHGTV RH+  + KG +TST
Sbjct: 278 ACKNYDGDVMSDVVAQAYGSLGLMTSVLIHPNGRTFESEAAHGTVQRHYMQYLKGKKTST 337

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           NSIASIFAWTRGLAHR +LD N RL++FA  LE ACV  VE G MTKDL LL       +
Sbjct: 338 NSIASIFAWTRGLAHRGRLDGNERLVKFANALEHACVRCVEKGIMTKDLYLL-----SKS 392

Query: 271 RSDYLNTEEFIDAVAAE 221
            + Y++T EF+DAV +E
Sbjct: 393 PNGYVDTFEFLDAVKSE 409
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>IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP)
          Length = 428

 Score =  168 bits (425), Expect = 1e-41
 Identities = 89/135 (65%), Positives = 104/135 (77%), Gaps = 1/135 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT E+EAAHGTVTRH+R +QKG ETST
Sbjct: 285 ALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETST 344

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKV 275
           NSIASIFAW+RGL  R +LD+   L +FA  LE A + TV + G MTKDLAL    +   
Sbjct: 345 NSIASIFAWSRGLLKRGELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGNNE-- 402

Query: 274 TRSDYLNTEEFIDAV 230
            RS Y+ TEEF+DAV
Sbjct: 403 -RSAYVTTEEFLDAV 416
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>IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP)
          Length = 498

 Score =  158 bits (399), Expect = 1e-38
 Identities = 82/135 (60%), Positives = 99/135 (73%), Gaps = 1/135 (0%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A KNYDGDVQSD +AQGFGSLGLMTS L+ P G+  E+EAAHGTVTRH+R HQKG ETST
Sbjct: 355 ALKNYDGDVQSDIVAQGFGSLGLMTSTLVTPTGEAFESEAAHGTVTRHYREHQKGRETST 414

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTV-ESGKMTKDLALLVHGSSKV 275
           N IASIFAWTRGL  R KLD+   ++ FA++LE AC+  V + G MTKDLAL      + 
Sbjct: 415 NPIASIFAWTRGLIQRGKLDETPDVVTFAEELERACIEVVNDEGIMTKDLAL---ACGRK 471

Query: 274 TRSDYLNTEEFIDAV 230
            R  ++ T E++ AV
Sbjct: 472 EREAWVTTREYMAAV 486
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>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GSLG++ S  L  PD KT + +A +  V  H       G++  N 
Sbjct: 246 NLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKAMYEPV--HGSAPDIAGKSIANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 266
           IA I ++   L +   + D       A KLE A    ++ G  T D  ++  G  +V   
Sbjct: 304 IAMIASFAMCLRYSFNMVDE------ATKLEAAIANVLDKGIRTAD--IMADGCRQV--- 352

Query: 265 DYLNTEEFIDAVAAE 221
               T +  DAV AE
Sbjct: 353 ---GTSDMGDAVLAE 364
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>LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/134 (29%), Positives = 54/134 (40%), Gaps = 1/134 (0%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-EAEAAHGTVTRHFRVHQKGGETST 452
           C N  GD+ SD LA   GSLGL++S  +   G  + E          H  +         
Sbjct: 239 CSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNI--------A 290

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IA I +    L +  K +      + AQ +E A    +  GKMTKDL           
Sbjct: 291 NPIAQILSAALMLKYSFKEE------QAAQDIENAISLALAQGKMTKDL----------N 334

Query: 271 RSDYLNTEEFIDAV 230
              YLNT+E  D +
Sbjct: 335 AKSYLNTDEMGDCI 348
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>LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 40/134 (29%), Positives = 54/134 (40%), Gaps = 1/134 (0%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-EAEAAHGTVTRHFRVHQKGGETST 452
           C N  GD+ SD LA   GSLGL++S  +   G  + E          H  +         
Sbjct: 239 CSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNI--------A 290

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N IA I +    L +  K +      + AQ +E A    +  GKMTKDL           
Sbjct: 291 NPIAQILSAALMLKYSFKEE------QAAQDIENAISLALAQGKMTKDL----------N 334

Query: 271 RSDYLNTEEFIDAV 230
              YLNT+E  D +
Sbjct: 335 AKSYLNTDEMGDCI 348
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>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GSLG++ S  L  PD KT + +A +  V  H       G    N 
Sbjct: 246 NLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKALYEPV--HGSAPDIAGTGVANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 266
           IA I ++   L +      +  L++ A  LE+A    ++ G  T D  ++  G  KV   
Sbjct: 304 IAMIASFAMCLRY------SFNLVKEADDLEKAIANVLDQGIRTGD--IMAEGCRKV--- 352

Query: 265 DYLNTEEFIDAVAAE 221
               T E  DA+ AE
Sbjct: 353 ---GTAEMGDAILAE 364
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>LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 368

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 36/119 (30%), Positives = 51/119 (42%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  +   GSLGL+ S  +    K  E  A +  +  H       G+   N I
Sbjct: 249 NLFGDMLSDQASMLTGSLGLLPSASLGAKNKDGEMRAMYEPI--HGSAPDIAGKEIANPI 306

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 266
           ASI ++   L +   LD        A  LE+A    +  G  TKD  +L  G  +V+ S
Sbjct: 307 ASILSFAMALRYSLDLDSE------ADALEKAVQDVLNDGLRTKD--ILSQGKKEVSTS 357
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>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTQSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 266
           A + +    L H         L + A K+E AC  T++ GK +TKDL     G+SK   S
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDLG----GNSKC--S 352

Query: 265 DYLNTEE 245
           D+  TEE
Sbjct: 353 DF--TEE 357
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>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate
           dehydrogenase subunits 3/4)
          Length = 366

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 266
           A + +    L H         L + A K+E AC  T++ GK +TKDL     G+SK   S
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIETACFATIKDGKSLTKDLG----GNSKC--S 352

Query: 265 DYLNTEE 245
           D+  TEE
Sbjct: 353 DF--TEE 357
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>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDL 305
           A + +    L H         L + A K+E AC  T++ GK +TKDL
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDL 345
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>LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GS+G++ S  L  PD KT + +A +  V  H       G+   N 
Sbjct: 246 NLFGDMLSDIAAMLTGSIGMLPSASLGAPDVKTKKRKALYEPV--HGSAPDIAGKGIANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           IA I ++   L +   + D       A +LE A    ++ G  TKD+
Sbjct: 304 IAMIASFAMCLRYSFGMVDE------ADRLEGAIAAVLDQGLRTKDI 344
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>LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S  +  DG ++  E  HG+           G+   N 
Sbjct: 239 ENMFGDILSDEASMLTGSLGMLPSASLTADGPSL-YEPVHGSAP------DIAGQNKANP 291

Query: 445 I-ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
           I A+I +    L H   L+  A +      +E+A    + +G  T DLA           
Sbjct: 292 IAAAILSAAMLLRHSFGLEKEAAV------IEQAVESVLHAGHRTADLA---------DG 336

Query: 268 SDYLNTEEFIDAVAA 224
           + YL T++ ++ + A
Sbjct: 337 NHYLGTDKMVEVITA 351
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>LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 34/124 (27%), Positives = 58/124 (46%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  +   GS+GL+ S  +   GK    E  HG+           G+   N I
Sbjct: 240 NLFGDILSDEASMLSGSIGLLPSASI--GGKAALYEPIHGSAP------DIAGQGIANPI 291

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD 263
           A+I + +  L H      +   +E A  +++A V T++ G  TKD+A    G+ ++  +D
Sbjct: 292 ATIASASMMLRH------SLGEVEAADAIDKAIVKTLKEGYRTKDIA--AFGAKEICTTD 343

Query: 262 YLNT 251
            + +
Sbjct: 344 EMGS 347
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>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 37.7 bits (86), Expect = 0.029
 Identities = 32/109 (29%), Positives = 52/109 (47%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A  N  GD+ SD  +   GS+G++ S  +  +GK +  E +HG+           G+   
Sbjct: 240 ATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKA 292

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           N +A+I +    L  R  L+D AR    AQ++E A    ++ G  T D+
Sbjct: 293 NPLATILSLAMLL--RYSLNDEAR----AQQVENAVQKVLQQGLRTSDI 335
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>LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 33/108 (30%), Positives = 47/108 (43%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD +A   GS+GL++S  M   G  +  E A G+           G+   N
Sbjct: 243 CSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGL-FEPAGGSAP------DIAGKGIAN 295

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
            IA I +    L H  K +      E A  +E A    + SG +T +L
Sbjct: 296 PIAQILSAALMLRHSLKQE------EAASAIERAVTKALNSGYLTGEL 337
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>LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GSLG++ S  +   D KT + ++ +  V  H       G+   N 
Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGEVDAKTGKRKSMYEPV--HGSAPDIAGKGMANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           +A + ++  G+A R  LD  A     A KL+EA    +  G  T D+
Sbjct: 304 VAMLASF--GMALRYSLDMGA----LADKLDEAIAAVLAKGLRTADI 344
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>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 36.6 bits (83), Expect = 0.064
 Identities = 31/109 (28%), Positives = 52/109 (47%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A  N  GD+ SD  +   GS+G++ S  +  +GK +  E +HG+           G+   
Sbjct: 240 ATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKA 292

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           N +A++ +    L  R  L+D AR    AQ++E A    ++ G  T D+
Sbjct: 293 NPLATVLSLAMLL--RYSLNDEAR----AQQVENAVQKVLQQGLRTGDI 335
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>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 36.2 bits (82), Expect = 0.083
 Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GSLG++ S  L   D KT + +A +  V  H       G+   N 
Sbjct: 246 NLFGDLLSDVAAMLTGSLGMLPSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 266
           IA I +    L +      +  L+  A +LE A  G ++ G  T D  +   G++KV   
Sbjct: 304 IAMIASLAMCLRY------SFGLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV--- 352

Query: 265 DYLNTEEFIDAVAAE 221
               T E  DA+ A+
Sbjct: 353 ---GTTEMGDAILAK 364
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>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 36.2 bits (82), Expect = 0.083
 Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GSLG++ S  L   D KT + +A +  V  H       G+   N 
Sbjct: 246 NLFGDLLSDVAAMLTGSLGMLPSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 266
           IA I +    L +      +  L+  A +LE A  G ++ G  T D  +   G++KV   
Sbjct: 304 IAMIASLAMCLRY------SFGLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV--- 352

Query: 265 DYLNTEEFIDAVAAE 221
               T E  DA+ A+
Sbjct: 353 ---GTTEMGDAILAK 364
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>LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 36.2 bits (82), Expect = 0.083
 Identities = 35/134 (26%), Positives = 56/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +      +  E A G+           G+   N
Sbjct: 245 CSNLFGDIVSDECAAITGSIGMLPSASLNEKNFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + H         L + A K++E+ V  ++ G  T D++   H       
Sbjct: 298 PIAQILSVSMLVRH------GMNLKKIADKIDESVVSVLKQGYRTADISNNSH------- 344

Query: 268 SDYLNTEEFIDAVA 227
            +YL T E  D +A
Sbjct: 345 -NYLKTSEMGDIIA 357
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>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/135 (28%), Positives = 60/135 (44%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 245 CSNIFGDIISDECAMITGSMGMLPSASLNQE-KFGMYEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            +A I   +  L  R  LD+     + A+ +E+A    +E+G++T DLA          +
Sbjct: 298 PVAQIL--SAALMLRYSLDEE----KAARAIEQAVSQALEAGELTADLA---------GK 342

Query: 268 SDYLNTEEFIDAVAA 224
              L+T E  D +AA
Sbjct: 343 GAALSTSEMGDKIAA 357
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>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 31/109 (28%), Positives = 52/109 (47%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           A  N  GD+ SD  +   GS+G++ S  +  +GK +  E +HG+           G+   
Sbjct: 240 ATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YEPSHGSAP------DIAGQNKA 292

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           N +A+I +    L  R  L+D AR    AQ++E +    ++ G  T D+
Sbjct: 293 NPLATILSLAMLL--RYSLNDEAR----AQQVENSVQKVLQQGLRTGDI 335
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>LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 33/135 (24%), Positives = 59/135 (43%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 245 CSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIEGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +      +  L + A K++++ +  ++ G  T D++           
Sbjct: 298 PIAQILSLSMLVRY------SMNLKKIADKIDQSVISVLKKGYRTADIS---------NN 342

Query: 268 SDYLNTEEFIDAVAA 224
           +DYL T E  D +A+
Sbjct: 343 NDYLKTNEMGDVIAS 357
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>LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 29/109 (26%), Positives = 50/109 (45%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  +   GS+G++ S  +   G  +  E + G+           G+   N
Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGLY-EPSGGSAP------DIAGKGVAN 295

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            IA + +    L +   +++ A       K+E A   T+ SGK T+D+A
Sbjct: 296 PIAQVLSAALMLRYSFSMEEEAN------KIETAVRKTIASGKRTRDIA 338
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>LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 29/109 (26%), Positives = 50/109 (45%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  +   GS+G++ S  +   G  +  E + G+           G+   N
Sbjct: 243 CENMFGDILSDEASIITGSIGMLPSASLSESGFGLY-EPSGGSAP------DIAGKGVAN 295

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            IA + +    L +   +++ A       K+E A   T+ SGK T+D+A
Sbjct: 296 PIAQVLSAALMLRYSFSMEEEAN------KIETAVRKTIASGKRTRDIA 338
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>LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 39/135 (28%), Positives = 55/135 (40%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+GL+ S  +  +   +  E A G+           G+   N
Sbjct: 242 CGNMFGDIISDEAAMLTGSMGLLASASLNTENFGL-FEPAGGSAP------DIAGQGIAN 294

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +           E A  +E A   T++ G  T D+A        V R
Sbjct: 295 PIAEILSAAMMLRYSLGYG------EAADAIEAAVEKTLDRGICTADIA--------VDR 340

Query: 268 SDYLNTEEFIDAVAA 224
           S  +NT E  DA+ A
Sbjct: 341 SQAVNTAEMGDAIVA 355
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>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 39/135 (28%), Positives = 59/135 (43%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S  +   G  +  E  HG+           G+   N 
Sbjct: 243 ENMFGDILSDEASMLTGSLGMLPSASLSSSGLHL-FEPVHGSAP------DIAGKGMANP 295

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 266
            A+I      L+    L  +  L E A+ +E+A    + SGK T+DLA      S+   S
Sbjct: 296 FAAI------LSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTRDLA-----RSEEFSS 344

Query: 265 DYLNTEEFIDAVAAE 221
               TEE   A+ +E
Sbjct: 345 TQAITEEVKAAIMSE 359
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>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 38/134 (28%), Positives = 54/134 (40%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNIFGDIISDECAMITGSMGMLPSASLNEKGFGL-YEPAGGSAP------DIAGKGIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L H   L+D A  +E A K        +  G  T DLA           
Sbjct: 297 PIAQILSAAMMLRHSFNLNDAATAIENAVK------NVLAEGHRTADLA---------DE 341

Query: 268 SDYLNTEEFIDAVA 227
           S  L+T++  D +A
Sbjct: 342 SQPLSTKQMGDLIA 355
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>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 32/108 (29%), Positives = 48/108 (44%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S  +   G  +  E  HG+           G+   N 
Sbjct: 243 ENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLY-EPVHGSAP------DIAGQNIANP 295

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           +A+I      L+    L  +  L   AQ +E A    + +GK TKDLA
Sbjct: 296 LAAI------LSAAMMLRTSFGLEAEAQAVEHAVDQVLRAGKRTKDLA 337
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>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 326

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 33/106 (31%), Positives = 44/106 (41%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   G LGL  S  +    +T   E  HG     F +  KG    T  I
Sbjct: 218 NMFGDIVSDLAAGLVGGLGLAPSANV--GERTAIFEPVHGAA---FDIAGKGIANPTAMI 272

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
            +     R   +          +E A+K+EEA   T++ GK T DL
Sbjct: 273 LTACMMLRHFGY----------VEEAKKVEEAVEKTIKEGKKTPDL 308
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>LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 30/108 (27%), Positives = 46/108 (42%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  A   GS+G++ S  +   G  +  E  HG+           G+   N 
Sbjct: 245 ENMFGDILSDEAAMLTGSIGMLPSASLGSGGPGL-YEPVHGSAP------DIAGQDKANP 297

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           +A + +    L H      + R  E AQ +E A    +E G  T D+A
Sbjct: 298 LAQVLSGAMLLRH------SLRQPEAAQAVERAVQTVLEQGYRTGDIA 339
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>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 349

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 29/106 (27%), Positives = 47/106 (44%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  +   GS+GL+ S  +  +GK +  E  HG+           G    N +
Sbjct: 239 NLFGDILSDLASACVGSIGLLPSASLNSEGKGL-YEPIHGSAP------DIAGLGKANPL 291

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A+I +    L +  K + +      A ++E+A    +E G  T DL
Sbjct: 292 ATILSGAMMLRYSLKREAD------ADRIEKAVSTALEKGARTADL 331
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>LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 329

 Score = 34.7 bits (78), Expect = 0.24
 Identities = 34/106 (32%), Positives = 43/106 (40%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   G LGL  S  +    K    E  HG+        Q  G+   N  
Sbjct: 220 NLFGDILSDEAAGLIGGLGLAPSANI--GEKNALFEPVHGSAP------QIAGKNIANPT 271

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A I   T  L H  K  +       AQK+E+A   T+  G +T DL
Sbjct: 272 AMILTTTLMLKHLNKKQE-------AQKIEKALQKTLAEGLVTPDL 310
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>LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GSLG++ S  L   D KT +  A +  V  H       G+   N 
Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGDTDPKTEKRRALYEPV--HGSAPDIAGQGLANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           IA + ++  G+A R   D      + A KL+ A    +  G  T DL
Sbjct: 304 IAMLASF--GMALRYSFDRG----DLADKLDAAIAAVLAKGLRTADL 344
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>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 34.3 bits (77), Expect = 0.32
 Identities = 38/134 (28%), Positives = 56/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A  +E A    +E G  T+DLA    G++ V  
Sbjct: 298 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTRDLA---RGAAAV-- 346

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 336

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 37/117 (31%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  +Q  GSLGL  S  +  D K++  E  HG     F +  KG     N  
Sbjct: 221 NVYGDILSDEASQIAGSLGLAPSANI-GDRKSM-FEPVHGAA---FDIAGKG---IANPT 272

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESG-KMTKDLALLVHGSSKV 275
           A + + +  L+   +L    + +  ++ LE A + T +SG K+T+D    V GS+K+
Sbjct: 273 AFLLSVSMMLSRMYELSKENKYILASKSLENAIIETYKSGNKLTED----VGGSAKL 325
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>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 33/108 (30%), Positives = 48/108 (44%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+GL+ S  +  DG  +  E A G+           G    N
Sbjct: 242 CPNLFGDILSDICAMITGSMGLLPSASLNSDGFGM-YEPAGGSAP------DIAGLGVAN 294

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
            IA I   +  L  R  L+  A     A+ +E+A    +++G +T DL
Sbjct: 295 PIAQIL--SAALMLRYSLNQGAA----AKAIEDAVSNALDNGVLTADL 336
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>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 40/134 (29%), Positives = 58/134 (43%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I   +  L  R  LD N    + A  +E+A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEEGVRTGDLA---RGAAAV-- 346

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 40/134 (29%), Positives = 58/134 (43%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I   +  L  R  LD N    + A  +E+A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEEGVRTGDLA---RGAAAV-- 346

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 40/134 (29%), Positives = 58/134 (43%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I   +  L  R  LD N    + A  +E+A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQIL--SLALLLRYSLDAN----DAATAIEQAINRALEEGVRTGDLA---RGAAAV-- 346

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 350

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 30/106 (28%), Positives = 44/106 (41%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GSLG++ S  +   GK    E  HG+           G+   N +
Sbjct: 240 NLFGDILSDAAAMLTGSLGMLPSAALGAPGKPGLYEPIHGSAP------DIAGKGLANPL 293

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A+I ++   L    K        E A  L  A    +++G  T+DL
Sbjct: 294 AAILSFEMALRWSLK------QTEAADALLAAVKAALDNGARTRDL 333
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>LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 33.1 bits (74), Expect = 0.70
 Identities = 29/106 (27%), Positives = 46/106 (43%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +  DG  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGSDGPGL-FEPVHGSAP------DIAGQDKANPL 298

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A +   +  +  R  LD      + A +LE+A    +E G  T D+
Sbjct: 299 AQVL--SAAMMLRYGLDQP----QAADRLEDAVKKVLEQGYRTGDI 338
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>LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 346

 Score = 33.1 bits (74), Expect = 0.70
 Identities = 32/124 (25%), Positives = 52/124 (41%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLGL  S     +G  +           +  +H    + +  +
Sbjct: 236 ENLFGDILSDEASTIPGSLGLSPSASFSLEGPRL-----------YEPIHGSAPDIANQN 284

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 266
           +A+ F     LA    L ++    + A +LE+A    ++ GK TKDL      +   T S
Sbjct: 285 LANPFGMILSLA--MCLRESFNFEDAASELEQAVYQLIKDGKTTKDL------NGHYTTS 336

Query: 265 DYLN 254
           D  N
Sbjct: 337 DIFN 340
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>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 33.1 bits (74), Expect = 0.70
 Identities = 33/109 (30%), Positives = 44/109 (40%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            IA I + T  L      DD       A  +E A    +E G  T DLA
Sbjct: 298 PIAQILSLTLLLRFSLGKDD------AADAIERAINQALEQGYRTADLA 340
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>LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 33.1 bits (74), Expect = 0.70
 Identities = 33/135 (24%), Positives = 57/135 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 245 CSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIEGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +      +  L   A K++++ +  ++ G  T D++           
Sbjct: 298 PIAQILSVSMLVRY------SMNLKTIADKIDQSVISVLKKGYRTADIS---------NN 342

Query: 268 SDYLNTEEFIDAVAA 224
           S YL T E  D +A+
Sbjct: 343 SHYLKTNEMGDVIAS 357
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>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           N  GD+ SD  A   GSLG++ S  +   D K+ + +A +  V  H       G+   N 
Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGEVDVKSKKRKALYEPV--HGSAPDIAGKGLANP 303

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           IA I ++  G+A R   D  A     A K++ A    + SG  T D+
Sbjct: 304 IAMISSF--GMALRYSFDMGA----LADKVDAAIAAVLASGLRTADI 344
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>LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 33/107 (30%), Positives = 46/107 (42%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GSLGL+ S      G     E A G+           G+   N I
Sbjct: 239 NMFGDILSDESAALPGSLGLLPSASF---GDKNLYEPAGGSAP------DIAGKNIANPI 289

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           A I +    L H      +  ++E A+K+E A    +E G  T+D+A
Sbjct: 290 AQILSLAMMLEH------SFGMVEEARKIERAVELVIEEGYRTRDIA 330
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>LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 33/134 (24%), Positives = 57/134 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CPNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +   L D       A K++++ +  ++ G  T D++           
Sbjct: 299 PIAQILSLSMLVRYGMNLKD------IADKIDKSVLSVLKKGYRTADIS---------NN 343

Query: 268 SDYLNTEEFIDAVA 227
           ++YL T E  D +A
Sbjct: 344 NNYLKTNEMGDVIA 357
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>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 377

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 33/107 (30%), Positives = 44/107 (41%), Gaps = 1/107 (0%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   G LGL  S  M  +G     E+ HGT           G+   N  
Sbjct: 269 NLYGDILSDMCAGLVGGLGLTPSGNMGLNGALF--ESVHGTAP------DIAGKDLANPT 320

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDL 305
           A + +    L H         L  +A K+E A   T++ GK +T DL
Sbjct: 321 ALLLSAVMMLRH-------MELNTYADKIERAAFETIKEGKYLTGDL 360
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>LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/107 (26%), Positives = 49/107 (45%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  +Q  GS+G++ S  +  +G+ +  E  HG+           G+   N +
Sbjct: 242 NMFGDILSDEASQLTGSIGMLPSASL-GEGRAM-YEPIHGSAP------DIAGQDKANPL 293

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           A+I +    L H    +       +AQ++E A    ++ G  T D+A
Sbjct: 294 ATILSVAMMLRHSLNAE------PWAQRVEAAVQRVLDQGLRTADIA 334
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>LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 32/109 (29%), Positives = 46/109 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  +G  +  E A G+           G+   N
Sbjct: 244 CSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-YEPAGGSAP------DIAGKGIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            IA I +    L +   L+      E A  +E A    + SG  T DLA
Sbjct: 297 PIAQILSAAMMLRYSFNLN------EAADAIESAVQKVLASGHRTADLA 339
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>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 38/134 (28%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 297 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTGDLA---RGAAAV-- 345

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 346 ----STDEMGDIIA 355
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>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 38/134 (28%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 297 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTGDLA---RGAAAV-- 345

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 346 ----STDEMGDIIA 355
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>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 38/134 (28%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 297 PIAQILSLALLLRYSLDADD------AASAIERAINRALEEGIRTGDLA---RGAAAV-- 345

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 346 ----STDEMGDIIA 355
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>LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/106 (26%), Positives = 46/106 (43%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +   G  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDAAAMLTGSIGMLPSASLGASGPGV-FEPVHGSAP------DIAGQDKANPL 298

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A +   +  +  R  LD      + A K+E+A +  +E G  T D+
Sbjct: 299 AQVL--SAAMMLRYALDQP----QAADKIEQAVLQVLEQGDRTGDI 338
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>LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 361

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 29/106 (27%), Positives = 45/106 (42%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +   G  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGESGPAL-FEPVHGSAP------DIAGQDKANPL 298

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A +   +  +  R  L+  A     AQ +EEA    ++ G  T DL
Sbjct: 299 AMVL--SAAMMLRYGLNQPAA----AQAIEEAITAVLDQGYRTGDL 338
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>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/108 (25%), Positives = 46/108 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/108 (25%), Positives = 46/108 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/108 (25%), Positives = 46/108 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/108 (25%), Positives = 46/108 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNMIEHGQTTADL 329
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>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/108 (25%), Positives = 46/108 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  +   GSLGL  S     DG  +           +  +H    + +  
Sbjct: 235 CENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL-----------YEPIHGSAPDIAGK 283

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           ++A+ F     LA    L ++    + A +LE+     +E G+ T DL
Sbjct: 284 NVANPFGMILSLA--MCLRESLNQPDAADELEQHIYSMIEHGQTTADL 329
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>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 32/109 (29%), Positives = 48/109 (44%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            +A I   +  L  R  L + A     AQ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----AQDIESAVSKALSAGELTADLA 341
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>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 36/134 (26%), Positives = 54/134 (40%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKDIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A+ +E+A    +  G  T DLA         + 
Sbjct: 298 PIAQILSLALLLRYSLGADD------AAEAIEKAVNTALAEGYRTADLA---------SA 342

Query: 268 SDYLNTEEFIDAVA 227
           S+ + T E  D +A
Sbjct: 343 SNAIGTSEMGDVIA 356
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>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.7 bits (73), Expect = 0.92
 Identities = 28/108 (25%), Positives = 48/108 (44%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S  +  DG  +  E  HG+           G+   N 
Sbjct: 242 ENLFGDILSDEASMVTGSLGMLPSASLTSDGPGL-YEPIHGSAP------DIAGKGVANP 294

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           +A+I +    L +   L + A+       +E+A    ++ G  T D+A
Sbjct: 295 LATIASCAMMLKYSFGLHEEAK------TIEDAIEAVLKQGYRTADIA 336
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>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 35/135 (25%), Positives = 57/135 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C+N  GD+ SD  A   GSLG++ S  +  +G     E + G+           G+   N
Sbjct: 245 CENMFGDILSDEAAMLTGSLGMLPSASLA-EGTFGMYEPSGGSAP------DIAGQGIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I      L+    L  +  +++ A  ++ A    ++ G  T+D+     G   V  
Sbjct: 298 PIAQI------LSMGMMLKFSFGMVDAADAIDNAVATVLDQGFRTRDIYQQKDGEKLV-- 349

Query: 268 SDYLNTEEFIDAVAA 224
               NT+E  DA+ A
Sbjct: 350 ----NTKEMGDAIIA 360
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>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 32/109 (29%), Positives = 48/109 (44%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            +A I   +  L  R  L + A     AQ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQALAAGELTADLA 341
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>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 32/109 (29%), Positives = 48/109 (44%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            +A I   +  L  R  L + A     AQ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQALAAGELTADLA 341
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>LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 32/109 (29%), Positives = 48/109 (44%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  M  + K    E A G+           G+   N
Sbjct: 246 CSNIFGDILSDECAMITGSMGMLPSASM-NESKFGLYEPAGGSAP------DIAGKNIAN 298

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            +A I   +  L  R  L + A     A+ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEEAA----ARDIENAVSQALAAGELTADLA 341
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>LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 32/134 (23%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +      +  E A G+           G+   N
Sbjct: 245 CSNLFGDIISDECAMITGSIGMLPSASLNEKNFGL-YEPAGGSAP------DIQGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +   L+      + A K++ A +  ++ G  T D++           
Sbjct: 298 PIAQILSLSMLIRYSMNLN------KIANKIDNAVINVLKKGYKTMDIS---------KD 342

Query: 268 SDYLNTEEFIDAVA 227
            +YL T E  D +A
Sbjct: 343 QNYLKTNEMGDVIA 356
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>LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 32/134 (23%), Positives = 57/134 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 247 CSNLFGDIVSDECAIITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIEGKNIAN 299

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +         L + A K++++ +  ++ G  T D++           
Sbjct: 300 PIAQILSVSMLVRY------GMNLKKIADKIDQSVISVLKKGYRTADIS---------NN 344

Query: 268 SDYLNTEEFIDAVA 227
           ++YL T E  D +A
Sbjct: 345 NNYLKTNEMGDVIA 358
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>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 35/117 (29%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+GL+ S  +   G  +  E A G+           G+   N
Sbjct: 245 CDNLFGDILSDECAMITGSMGLLPSASLNQSGFGL-YEPAGGSAP------DIAGKGVAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFA-QKLEEACVGTVE----SGKMTKDLALLV 293
            IA I +    L +    D+ AR +E A  +   A VGT +    +G  T D+A  +
Sbjct: 298 PIAQILSAALMLRYSLGQDEAARTIEKAVAEAVAAGVGTPDIFPNAGYTTNDVAAAI 354
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>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 36/126 (28%), Positives = 53/126 (42%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNIFGDILSDECAMITGSMGMLPSASLNEKGFGL-YEPAGGSAP------DIAGKGIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I   +  L  R  L  N    + A  +E+A    +E G  T DLA    G+ K   
Sbjct: 298 PIAQIL--SAALLLRYSLGHN----DAANAIEQAVNYALEQGYRTTDLA----GNGKAIS 347

Query: 268 SDYLNT 251
           +D + +
Sbjct: 348 TDEMGS 353
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>LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 32/134 (23%), Positives = 59/134 (44%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S         +  E A G+           G+ + N
Sbjct: 245 CSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YEPAGGSAP------DIAGKNTAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +  KL+      + A K+++A   ++++G  T D++           
Sbjct: 298 PIAQILSLSMLVRYGMKLN------KIADKIDDAVALSLKAGYRTADIS---------ND 342

Query: 268 SDYLNTEEFIDAVA 227
           +++L T E  D +A
Sbjct: 343 NNFLKTNEMGDVIA 356
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>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)|
          Length = 537

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 7/83 (8%)
 Frame = -3

Query: 607 VQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTV-------TRHFRVHQKGGETSTN 449
           VQ  F A GF      T V+  PDG  + A +A GT+        +  R+  K   +S N
Sbjct: 452 VQQTFSAPGFKCGSDWTRVIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSSIN 511

Query: 448 SIASIFAWTRGLAHRAKLDDNAR 380
           ++    AW+    H   +D  +R
Sbjct: 512 AV----AWSPSGTHVVSVDKGSR 530
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>IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 416

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 33/134 (24%), Positives = 51/134 (38%)
 Frame = -3

Query: 631 ACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETST 452
           AC N +GD  SD LA   G +G+     +  +      EA HGT  ++       G+   
Sbjct: 300 ACMNLNGDYISDALAAQVGGIGIAPGANIGDECALF--EATHGTAPKY------AGQDKV 351

Query: 451 NSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVT 272
           N  + I +    L H           E A  + +   G + +  +T D   L+ G+    
Sbjct: 352 NPGSIILSAEMMLRHMG-------WTEAADLIVKGMEGAINAKTVTYDFERLMDGAK--- 401

Query: 271 RSDYLNTEEFIDAV 230
               L   EF DA+
Sbjct: 402 ---LLKCSEFGDAI 412
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>LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 30/106 (28%), Positives = 48/106 (45%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +   G+ +  E  HG+           G+   N +
Sbjct: 244 NMFGDILSDCAAMLTGSIGMLPSASLDQSGRGM-YEPIHGSAP------DIAGQGIANPL 296

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A+I +    L  R  LD  A+    A +LE+A    ++ G  T D+
Sbjct: 297 ATILSVAMML--RYSLDSPAQ----ATRLEKAVGAVLDQGLRTPDI 336
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>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 38/134 (28%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 297 PIAQILSLALLLRYSLDADD------AACAIERAINRALEEGIRTGDLA---RGAAAV-- 345

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 346 ----STDEMGDIIA 355
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>LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 31/109 (28%), Positives = 47/109 (43%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +      +  E A G+           G+   N
Sbjct: 246 CSNIFGDIISDECAMITGSMGMLPSASLNESNFGL-YEPAGGSAP------DIAGKNIAN 298

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            +A I   +  L  R  L +     E AQ +E A    + +G++T DLA
Sbjct: 299 PVAQIL--SAALMLRYSLGEE----EAAQSIEAAVSKALSAGELTADLA 341
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>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 38/134 (28%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQILSLALLLRYSLDADD------AACAIERAINRALEEGIRTGDLA---RGAAAV-- 346

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 33/134 (24%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +    K    E A G+           G+   N
Sbjct: 245 CSNIFGDIISDECAMITGSIGMLPSASL-NSKKFGLYEPAGGSAP------DIEGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + H   L+      E A K++ +    +++G  T D++           
Sbjct: 298 PIAQILSLSMLIRHSMNLN------EIADKIDSSVYRALKAGYRTLDIS---------DG 342

Query: 268 SDYLNTEEFIDAVA 227
            +Y+ T E  D +A
Sbjct: 343 KNYIKTNEMGDIIA 356
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>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 39/136 (28%), Positives = 54/136 (39%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GSLG++ S  +  +G     E A G+           G+   N
Sbjct: 245 CPNMFGDILSDEAAMLTGSLGMLPSASLA-EGSFGMYEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            +A I +    L +   L D A  +E   K  E C+    +G  T D+     G   V  
Sbjct: 298 PVAQILSAAMLLRYSCGLADAADAVE---KAVENCLA---AGLRTGDIYQDADGEQLV-- 349

Query: 268 SDYLNTEEFIDAVAAE 221
               +T    DAV AE
Sbjct: 350 ----STSAMGDAVVAE 361
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>LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 32/109 (29%), Positives = 45/109 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 244 CSNIFGDIISDEAAMITGSMGMLPSASLNEAGFGL-YEPAGGSAP------DIAGKGIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            IA I +    L +   L+      E A  +E A    + SG  T DLA
Sbjct: 297 PIAQILSAAMMLRYSFNLN------EAADAIESAVQKVLASGHRTADLA 339
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>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 360

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 30/107 (28%), Positives = 46/107 (42%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +   GK +  E  HG+           G    N I
Sbjct: 244 NMFGDILSDCAAMLTGSIGMLPSASLAESGKGM-YEPIHGSAP------DIAGRGIANPI 296

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           A+I +    L  R   DD       A+++ +A    ++ G  T D+A
Sbjct: 297 ATILSLAMML--RYSFDDAVS----AERIGKAVQTALDQGFRTADIA 337
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>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 28/106 (26%), Positives = 46/106 (43%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +  +G  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGAEGPGV-FEPVHGSAP------DIAGQDKANPL 298

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A +   +  +  R  LD+     E A ++E A    ++ G  T DL
Sbjct: 299 AQVL--SAAMMLRYGLDEP----EAAARIEAAVNQVLDQGYRTGDL 338
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>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 31/108 (28%), Positives = 45/108 (41%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLGL+ S  M    K    E  HG+           G  + N 
Sbjct: 242 ENLFGDILSDEASMITGSLGLLPSASM-NTSKVGLFEPVHGSAP------DIAGTGAANP 294

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           +A+I +    L +   L D A+ +E A          +  G  TKD+A
Sbjct: 295 LATILSAAMMLQYSFGLADEAKAIEVAVD------RVLAQGVRTKDIA 336
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>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 32/109 (29%), Positives = 43/109 (39%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            IA I +    L      DD       A  +E A    +E G  T DLA
Sbjct: 298 PIAQILSLILLLRFSLGKDD------AADAIERAINQALEQGYRTADLA 340
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>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 38/134 (28%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +   G  +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAP------DITGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    DD       A  +E A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQILSLALLLRYSLDADD------AACAIERAINRALEEGIRTGDLA---RGAAAV-- 346

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 37/134 (27%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +      +  E A G+           G+   N
Sbjct: 245 CSNLFGDILSDECAMITGSMGMLPSASLNEQEFGL-YEPAGGSAP------DIAGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I +    L +    D      E A  +E+A    +E G  T DLA    G++ V  
Sbjct: 298 PIAQILSLALLLRYSLDAD------EAATAIEQAINRALEEGVRTSDLA---RGAAAV-- 346

Query: 268 SDYLNTEEFIDAVA 227
               +T+E  D +A
Sbjct: 347 ----STDEMGDIIA 356
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>LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 32/134 (23%), Positives = 56/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  + K    E A G+           G+   N
Sbjct: 245 CSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYEPAGGSAP------DIEGKNIAN 297

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +         L   A K++++ +  ++ G  T D++           
Sbjct: 298 PIAQILSVSMLVRY------GMNLKTIADKIDQSVISVLKKGYRTADIS---------NN 342

Query: 268 SDYLNTEEFIDAVA 227
           ++YL T E  D +A
Sbjct: 343 NNYLKTNEMGDVIA 356
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>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 31/106 (29%), Positives = 43/106 (40%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GSLG++ S  +         +A +  V  H       G+   N I
Sbjct: 244 NLFGDILSDCAAMLTGSLGMLPSASLGAPMANGRPKALYEPV--HGSAPDIAGQGKANPI 301

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A I ++   +A R   D  A     A +LE A    +  G  T DL
Sbjct: 302 ACILSF--AMALRYSFDQGAE----ADRLEAAVEQVLADGVRTADL 341
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>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +  +GK +  E  HG+           G+   N +
Sbjct: 245 NLFGDILSDEAAMLTGSIGMLPSASLDENGKGM-YEPCHGSAP------DIAGQNVANPL 297

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFA--QKLEEAC------------VGTVESGK 320
           A+I +    L +  + +  A+ +E A  Q L++              VGTVE G+
Sbjct: 298 ATILSVAMMLRYTFREEAAAKAIEDAVGQVLDQGLRTADIMSEGMQRVGTVEMGQ 352
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>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC|
           1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 28/102 (27%), Positives = 43/102 (42%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   G LGL  S  +   G  + AEA HG+           G+   N  
Sbjct: 258 NLYGDIISDLCAGLIGGLGLTPSCNIGEGGIAL-AEAVHGSAP------DIAGKNLANPT 310

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKM 317
           A + +    L H         L + A ++++A + T+  GK+
Sbjct: 311 ALLLSSVSMLRH-------LELHDKADRIQDAILKTIAGGKV 345
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>LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 31/109 (28%), Positives = 45/109 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S  +  +G  +  E A G+           G+   N
Sbjct: 244 CSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-YEPAGGSAP------DIAGKGIAN 296

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
            IA I +    L +   L+      E A  +E A    +  G  T DLA
Sbjct: 297 PIAQILSAAMMLRYSFNLN------EAATAIENAVQKVLADGHRTGDLA 339
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>LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 369

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 4/90 (4%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCP---DGK-TIEAEAAHGTVTRHFRVHQKGGETS 455
           N  GD+ SD  +   GSLG++ S  + P   DGK     E  HG+           G+  
Sbjct: 247 NLFGDILSDLASMLTGSLGMLPSATLGPVRADGKRNALYEPIHGSAP------DIAGKGI 300

Query: 454 TNSIASIFAWTRGLAHRAKLDDNARLLEFA 365
            N +A I ++   L +     ++A L+E A
Sbjct: 301 ANPLAQILSFAMLLRYSLNRAEDADLIEMA 330
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>LEU3_BUCUL (Q9AQC8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH) (Fragment)
          Length = 126

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 31/134 (23%), Positives = 55/134 (41%)
 Frame = -3

Query: 628 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 449
           C N  GD+ SD  A   GS+G++ S         +  E A G+           G+   N
Sbjct: 8   CSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YEPAGGSAP------DIAGKNIAN 60

Query: 448 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 269
            IA I + +  + +  KL       + A K++++    +++G  T D++           
Sbjct: 61  PIAQILSLSMLVRYGMKLK------KIADKIDKSVASALKAGYRTADIS---------NN 105

Query: 268 SDYLNTEEFIDAVA 227
           + YL T E  D ++
Sbjct: 106 NSYLKTNEMGDVIS 119
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>LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 360

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 35/133 (26%), Positives = 58/133 (43%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  +   GS+G++ S  +  + K +  E  HG+           G+   N +
Sbjct: 244 NMFGDILSDEASMLTGSIGMLPSASLDANNKGM-YEPCHGSAP------DIAGQGIANPL 296

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD 263
           A+I + +  L +      +  L E A  +E+A    ++ G  T D  +   G +KV    
Sbjct: 297 ATILSVSMMLRY------SFNLTEAADAIEQAVSRVLDQGLRTGD--IWSAGCTKV---- 344

Query: 262 YLNTEEFIDAVAA 224
              T+E  DAV A
Sbjct: 345 --GTQEMGDAVVA 355
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>INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin beta-A chain)|
          Length = 425

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
 Frame = -3

Query: 520 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTR-GLAHRAKLDDNARLLEFAQKLEEAC 344
           AE+     T HF + Q+G + S    A I+ + +   A+R +     RL +  + L+   
Sbjct: 127 AESGTARKTLHFEISQEGSDLSVVERAEIWLFLKVPKANRTRSKVTIRLFQQQKHLQ--- 183

Query: 343 VGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDA 233
            G++++G+  +++ L      K  +S+ L +E+ +DA
Sbjct: 184 -GSLDAGEEAEEVGL------KGEKSEMLISEKVVDA 213
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>LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 28/106 (26%), Positives = 46/106 (43%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +   GK +  E  HG+           G+   N +
Sbjct: 250 NLFGDILSDEAAMLTGSIGMLPSASLDEAGKGM-YEPCHGSAP------DIAGQDIANPL 302

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A+I +    L +  K +        AQ +E+A    ++ G  T D+
Sbjct: 303 ATILSVAMMLRYTFKQE------VAAQAIEQAVSDVLDDGLRTVDI 342
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>Y1185_METJA (Q58585) Hypothetical protein MJ1185|
          Length = 622

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 22/62 (35%), Positives = 34/62 (54%)
 Frame = -1

Query: 540 LMVKQSKPKLPMAQSLVISVFTRKVVKPAQTALLPSLLGQEDLHTGQS*TTTLDFLNLHR 361
           L+V+  K +LP+ ++L I  F RK +KP    L+  LLG ED+          D +NL+R
Sbjct: 504 LVVESIKLELPI-ENLGICRFHRKWLKPVLKELVKELLGIEDI--------VEDSINLYR 554

Query: 360 NL 355
            +
Sbjct: 555 EI 556
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>LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 30/107 (28%), Positives = 47/107 (43%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S      G ++  E  HG+           G+   N 
Sbjct: 234 ENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-YEPIHGSAP------DIAGKNKANP 286

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           IA +    R +A    L  +  L      +EEA    ++SGK T+D+
Sbjct: 287 IAMM----RSVA--MMLGQSFGLTREGCAIEEAISAVLKSGKCTEDI 327
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>LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 30/107 (28%), Positives = 46/107 (42%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S      G ++  E  HG+           G+   N 
Sbjct: 234 ENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-YEPIHGSAP------DIAGKNKANP 286

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           IA +    R +A    L  +  L      +EEA    ++SGK T D+
Sbjct: 287 IAMM----RSVA--MMLGQSFGLTREGYAIEEAVSAVLKSGKCTADI 327
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>LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 366

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 26/87 (29%), Positives = 39/87 (44%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S  +  DG  +  E  HG+           G+   N 
Sbjct: 238 ENLFGDILSDEASVLTGSLGMLPSASLRADGLGL-YEPVHGSAP------DIAGKGIANP 290

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFA 365
           +A I +    L H   L D A+ +E A
Sbjct: 291 LAMILSAALMLEHSFGLVDEAKEIERA 317
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>LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 34/114 (29%), Positives = 50/114 (43%), Gaps = 14/114 (12%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +  + K +  E +HG+           G+   N +
Sbjct: 243 NMFGDILSDEAAMLTGSIGMLPSASLDANNKGL-YEPSHGSAP------DIAGKGIANPL 295

Query: 442 ASIFA------WTRGLAHRAKLDDNARLLEFAQK------LEEAC--VGTVESG 323
           A+I +      +T G A +A   +NA     AQ       L   C  VGTVE G
Sbjct: 296 ATILSAAMMLRYTLGKAEQADRIENAVKKVLAQGYRTGDILTPGCKQVGTVEMG 349
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>LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 371

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 30/108 (27%), Positives = 46/108 (42%)
 Frame = -3

Query: 625 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 446
           +N  GD+ SD  +   GSLG++ S  +   G ++  E  HG+           G    N 
Sbjct: 243 ENMFGDILSDEASMLSGSLGMLPSASLSASGPSL-YEPVHGSAP------DIAGMNKANP 295

Query: 445 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 302
           IA+I      L+    L  +  L   A+ +E A    ++ G  T DLA
Sbjct: 296 IAAI------LSAAMMLRLSFGLTAEAEAVEHAVRQALDQGLRTADLA 337
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>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 30/106 (28%), Positives = 42/106 (39%)
 Frame = -3

Query: 622 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 443
           N  GD+ SD  A   GS+G++ S  +  DG  +  E  HG+            + +   I
Sbjct: 244 NLFGDILSDIAAMLTGSIGMLPSASLTTDGPGV-FEPVHGSAP----------DIAGKDI 292

Query: 442 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 305
           A+  A     A   K+  N    E A  LE A    +  G  T DL
Sbjct: 293 ANPIAMLLSAAMMLKIALNE--TEAATFLENAINEILNDGYRTSDL 336
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>SYNJ1_BOVIN (O18964) Synaptojanin-1 (EC 3.1.3.36) (Synaptic|
           inositol-1,4,5-trisphosphate 5-phosphatase 1) (p150)
           (Fragment)
          Length = 1324

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
 Frame = -3

Query: 499 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLE-------FAQKLEEA-- 347
           VTR   V +     + +SI+ I+A T  L  +AKL D AR +        F    +EA  
Sbjct: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVSRTIQNNFFDSSKQEAID 477

Query: 346 ---CVGTVESGKMTKDLALLVHGSSKVT 272
                 T+ S    K  ALL  GS +V+
Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVS 505


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,448,298
Number of Sequences: 219361
Number of extensions: 1553883
Number of successful extensions: 4379
Number of sequences better than 10.0: 127
Number of HSP's better than 10.0 without gapping: 4252
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4352
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5881538857
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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