>COP1_ARATH (P43254) Ubiquitin-protein ligase COP1 (EC 6.3.2.-) (Constitutive|
           photomorphogenesis protein 1)
          Length = 675

 Score =  103 bits (258), Expect = 3e-22
 Identities = 52/96 (54%), Positives = 67/96 (69%), Gaps = 1/96 (1%)
 Frame = -1

Query: 574 VIDN-PIQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPI 398
           V DN P++TF GHTN KNFVGL+++  Y+A GSETNEV+VYHK    PV +++F   D  
Sbjct: 577 VKDNLPVRTFRGHTNEKNFVGLTVNSEYLACGSETNEVYVYHKEITRPVTSHRFGSPDMD 636

Query: 397 SGQEIDDQSQFISCVCWRGQSSTLLSANSSGNIKVL 290
             +E +  S FIS VCW+  S T+L+ANS G IKVL
Sbjct: 637 DAEE-EAGSYFISAVCWKSDSPTMLTANSQGTIKVL 671

>COP1_PEA (P93471) Ubiquitin ligase protein COP1 (EC 6.3.2.-) (Constitutive|
           photomorphogenesis protein 1)
          Length = 672

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 48/91 (52%), Positives = 60/91 (65%)
 Frame = -1

Query: 562 PIQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQEI 383
           P++TF GH N KNFVGL++   YIA GSETNEVFVYHK    P+  ++F   D +   E 
Sbjct: 579 PVRTFRGHANEKNFVGLTVRSEYIACGSETNEVFVYHKEISKPLTWHRFGTLD-MEDAED 637

Query: 382 DDQSQFISCVCWRGQSSTLLSANSSGNIKVL 290
           +  S FIS VCW+    T+L+ANS G IKVL
Sbjct: 638 EAGSYFISAVCWKSDRPTILTANSQGTIKVL 668

>RFWD2_MOUSE (Q9R1A8) Ring finger and WD repeat domain protein 2 (EC 6.3.2.-)|
           (Ubiquitin-protein ligase COP1) (Constitutive
           photomorphogenesis protein 1 homolog) (mCOP1)
          Length = 733

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 42/98 (42%), Positives = 65/98 (66%), Gaps = 6/98 (6%)
 Frame = -1

Query: 559 IQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPI--SGQE 386
           +++F GH N KNFVGL+ +  YIA GSE N +++Y+K     +L +KF+    +    ++
Sbjct: 635 LRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRK 694

Query: 385 IDDQSQFISCVCWR----GQSSTLLSANSSGNIKVLEM 284
            DD ++F+S VCWR    G+S+ L++ANS G IKVLE+
Sbjct: 695 EDDTNEFVSAVCWRALSDGESNVLIAANSQGTIKVLEL 732

>RFWD2_HUMAN (Q8NHY2) Ring finger and WD repeat domain protein 2 (EC 6.3.2.-)|
           (Ubiquitin-protein ligase COP1) (Constitutive
           photomorphogenesis protein 1 homolog) (hCOP1)
          Length = 731

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 42/98 (42%), Positives = 65/98 (66%), Gaps = 6/98 (6%)
 Frame = -1

Query: 559 IQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPI--SGQE 386
           +++F GH N KNFVGL+ +  YIA GSE N +++Y+K     +L +KF+    +    ++
Sbjct: 633 LRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRK 692

Query: 385 IDDQSQFISCVCWR----GQSSTLLSANSSGNIKVLEM 284
            DD ++F+S VCWR    G+S+ L++ANS G IKVLE+
Sbjct: 693 EDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLEL 730

>WDR26_MOUSE (Q8C6G8) WD-repeat protein 26|
          Length = 514

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = -1

Query: 505 SDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQEIDDQSQFISCVCWRGQ-SST 329
           ++ +IA+GSE ++V+++HK   +P+              E+   ++ ++CV W  Q  S 
Sbjct: 435 NEDFIASGSEDHKVYIWHKRSELPI-------------AELTGHTRTVNCVSWNPQIPSM 481

Query: 328 LLSANSSGNIKV 293
           + SA+  G +++
Sbjct: 482 MASASDDGTVRI 493

>WDR26_HUMAN (Q9H7D7) WD-repeat protein 26|
          Length = 514

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
 Frame = -1

Query: 505 SDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQEIDDQSQFISCVCWRGQ-SST 329
           ++ +IA+GSE ++V+++HK   +P+              E+   ++ ++CV W  Q  S 
Sbjct: 435 NEDFIASGSEDHKVYIWHKRSELPI-------------AELTGHTRTVNCVSWNPQIPSM 481

Query: 328 LLSANSSGNIKV 293
           + SA+  G +++
Sbjct: 482 MASASDDGTVRI 493

>YH92_CAEEL (Q23256) Hypothetical WD-repeat protein ZC302.2|
          Length = 501

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 26/120 (21%), Positives = 45/120 (37%)
 Frame = -1

Query: 559 IQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQEID 380
           ++T +GHT + + +  S    Y+ TGS   ++ V+             N  D    Q + 
Sbjct: 206 VKTISGHTKSVSVIKFSYCGKYLGTGSADKQIKVW-------------NTVDMTYLQTLA 252

Query: 379 DQSQFISCVCWRGQSSTLLSANSSGNIKVLEMD*PCAEGRGCCLVSSRNGPTSVTCYQGN 200
                I+   W   S  + SA+    +K+ ++        G CL + R     V C   N
Sbjct: 253 SHQLGINDFSWSSNSQFIASASDDTTVKIFDVI------SGACLRTMRGHTNYVFCCSFN 306

>YCW2_YEAST (P25382) Hypothetical WD-repeat protein YCR072C|
          Length = 515

 Score = 32.7 bits (73), Expect = 0.80
 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 15/113 (13%)
 Frame = -1

Query: 586 NQARVID----NPIQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYK 419
           N AR+ D     P+ T  GH N    V  S     IATGS  N + ++            
Sbjct: 166 NTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLW------------ 213

Query: 418 FNVTDPISGQEIDD----QSQFISCVCWR-------GQSSTLLSANSSGNIKV 293
               DP SGQ + D     S++I+ + W        G    L S++  G IK+
Sbjct: 214 ----DPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKI 262

>HIRL_SCHPO (P87314) Histone transcription regulator 1 homolog|
          Length = 932

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
 Frame = -1

Query: 541 HTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKF-----NVTDPISGQEIDD 377
           HT T   V  S +  Y+A+GS+   V ++HK   +P L   F     +  +  S + +  
Sbjct: 73  HTGTVTSVRFSPNGQYLASGSDDRVVIIWHKEEAIPGLGSTFGSGEKHTENWRSYRRLLG 132

Query: 376 QSQFISCVCWRGQSSTLLSANSSGNIKV 293
               I  +CW   S  ++S     +I V
Sbjct: 133 HDNDIQDLCWSYDSQLVVSVGLDSSIIV 160

>TAF73_SCHPO (O74319) Transcription initiation factor TFIID subunit taf73|
           (Transcription initiation factor TFIID 73 kDa subunit)
           (TAFII-73)
          Length = 642

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 22/93 (23%), Positives = 39/93 (41%)
 Frame = -1

Query: 562 PIQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQEI 383
           P++ F GH N  + V    +  Y+ATGS  +   ++       V  +  + +        
Sbjct: 479 PLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSP------- 531

Query: 382 DDQSQFISCVCWRGQSSTLLSANSSGNIKVLEM 284
                 +S +C      +L SA+ SG IKV ++
Sbjct: 532 ------VSALCMSADGLSLASADESGIIKVWDL 558

>KI67_HUMAN (P46013) Antigen KI-67|
          Length = 3256

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 11/39 (28%), Positives = 21/39 (53%)
 Frame = -1

Query: 403  PISGQEIDDQSQFISCVCWRGQSSTLLSANSSGNIKVLE 287
            P+  +  +  ++ + C+  RGQ +TLL     G +K +E
Sbjct: 888  PVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIE 926

>SSB_BACHD (Q9K5N9) Single-stranded DNA-binding protein (SSB)|
           (Helix-destabilizing protein)
          Length = 168

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 13/45 (28%), Positives = 24/45 (53%)
 Frame = -1

Query: 433 VLAYKFNVTDPISGQEIDDQSQFISCVCWRGQSSTLLSANSSGNI 299
           V  +   V  P S Q+ + ++ FI+CV WR Q+  + +    G++
Sbjct: 26  VANFTLAVNRPFSNQQGEREADFINCVVWRKQAENVANYLKKGSL 70

>CPNE4_MOUSE (Q8BLR2) Copine-4 (Copine IV)|
          Length = 557

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
 Frame = -1

Query: 586 NQARVIDNPIQTFTGHTNTKN----FVGLSISDGYIATGSETNEVFVYHKAFPMPVL 428
           N A +I    ++ +  TNTK     F+ L ++DG I   ++T E  V+    PM V+
Sbjct: 412 NIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVI 468

>CPNE4_HUMAN (Q96A23) Copine-4 (Copine IV) (Copine-8)|
          Length = 557

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
 Frame = -1

Query: 586 NQARVIDNPIQTFTGHTNTKN----FVGLSISDGYIATGSETNEVFVYHKAFPMPVL 428
           N A +I    ++ +  TNTK     F+ L ++DG I   ++T E  V+    PM V+
Sbjct: 412 NIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVI 468

>YNA6_YEAST (P41318) Hypothetical 34.0 kDa Trp-Asp repeats-containing protein|
           in SIS1-MRPL2 intergenic region
          Length = 303

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
 Frame = -1

Query: 565 NPIQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQE 386
           NP+ +F GH      V     + ++ T SE   + V+    P     YK N   P++   
Sbjct: 66  NPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYKHNA--PVNEVV 123

Query: 385 I-DDQSQFISC 356
           I  +Q + ISC
Sbjct: 124 IHPNQGELISC 134

>SSB_OCEIH (Q8CX55) Single-stranded DNA-binding protein (SSB)|
           (Helix-destabilizing protein)
          Length = 161

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
 Frame = -1

Query: 442 PMPVLAYKFN--VTDPISGQEIDDQSQFISCVCWRGQSSTLLSANSSGNI 299
           P  V    FN  V  P S Q+ + ++ FI+CV WR  +  L +    G++
Sbjct: 21  PNGVAVANFNIAVNRPFSNQQGNREADFINCVIWRRPAENLANYMKKGSM 70

>MIRB_EMENI (Q870L2) Siderophore iron transporter mirB (Major facilitator|
           iron-regulated transporter B) (Triacetylfusarinine C
           permease)
          Length = 604

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
 Frame = -1

Query: 493 IATGSETNEVFVYHKAF--PMPVLAYKFNVTDPISGQEIDDQSQFISCVCWRGQSSTLL 323
           I TG     +FV ++A+  P P L Y+F     + G  + D +  +S  CW    ++ L
Sbjct: 331 IVTGFVVMVLFVLYQAYWAPQPFLKYEFLTNRTVLGACLIDATYQMSYYCWNSYFNSFL 389

>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC|
           2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene
           serine/threonine-protein kinase) (C-MIL)
          Length = 647

 Score = 30.0 bits (66), Expect = 5.2
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
 Frame = +1

Query: 85  PTLTLDIANTTTLPVVPN-----SGVPLFPPLP*RDYKIARHAHSPDNKSLKSVHFYSKP 249
           PT+ +D +N   L + PN     SGVP  PPL  R     R   S     + S H YS P
Sbjct: 181 PTMCVDWSNIRQLLLFPNSNISDSGVPALPPLTMR-----RMRESVSRIPVSSQHRYSTP 235

>SCONB_EMENI (Q00659) Sulfur metabolite repression control protein|
          Length = 678

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 16/34 (47%), Positives = 20/34 (58%)
 Frame = -1

Query: 556 QTFTGHTNTKNFVGLSISDGYIATGSETNEVFVY 455
           +TFTGH+     +GL   D   ATGSE  EV +Y
Sbjct: 643 RTFTGHSGPVTCIGL--GDSRFATGSEDCEVRMY 674

>WDR1_CHICK (O93277) WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)|
          Length = 609

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 24/90 (26%), Positives = 35/90 (38%)
 Frame = -1

Query: 553 TFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQEIDDQ 374
           T + HT   N V  S      AT S   ++F+Y       V A        + G +  D 
Sbjct: 186 TLSDHTRFVNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCA--------LGGGKAHDG 237

Query: 373 SQFISCVCWRGQSSTLLSANSSGNIKVLEM 284
              I  + W   SS LLSA+     K+ ++
Sbjct: 238 G--IYAISWSPDSSQLLSASGDKTAKIWDV 265

>LNT_VIBPA (Q87RP8) Apolipoprotein N-acyltransferase (EC 2.3.1.-) (ALP|
           N-acyltransferase)
          Length = 505

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
 Frame = -1

Query: 436 PVLAYKFNVTDPISGQEIDDQSQFISCV---CWRGQSSTLLSANSSGNIKVLEMD*PCAE 266
           P L Y+    + +  Q + D++ FI  +    W G S   L       ++ LE+  P   
Sbjct: 379 PALCYEIIFNEQVR-QNVTDETDFILTLSNDAWFGHSIGPLQHMEIARMRALELGKPLIR 437

Query: 265 GRGCCLVSSRNGPTSVTCYQGNV 197
                  S+ NG T+VT Y+G +
Sbjct: 438 -------STNNGLTAVTDYKGKI 453

>PK1IP_BRARE (Q6TNS2) p21-activated protein kinase-interacting protein 1-like|
           (PAK1-interacting protein 1-like)
          Length = 368

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 13/33 (39%), Positives = 21/33 (63%)
 Frame = -1

Query: 553 TFTGHTNTKNFVGLSISDGYIATGSETNEVFVY 455
           TFT H +T +   +S S+ +IATGS+   + +Y
Sbjct: 40  TFTHHAHTASLNAVSSSNQFIATGSKDETIQLY 72

>PKWA_THECU (P49695) Probable serine/threonine-protein kinase pkwA (EC|
           2.7.11.1)
          Length = 742

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 20/89 (22%), Positives = 41/89 (46%)
 Frame = -1

Query: 559 IQTFTGHTNTKNFVGLSISDGYIATGSETNEVFVYHKAFPMPVLAYKFNVTDPISGQEID 380
           + TF GHT+    V  S     +A+GS+   + ++       V A + + T       ++
Sbjct: 661 LHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLW------DVAAQEEHTT-------LE 707

Query: 379 DQSQFISCVCWRGQSSTLLSANSSGNIKV 293
             ++ +  V +  + +TL SA+  G I++
Sbjct: 708 GHTEPVHSVAFHPEGTTLASASEDGTIRI 736

>STAT1_HUMAN (P42224) Signal transducer and activator of transcription|
           1-alpha/beta (Transcription factor ISGF-3 components
           p91/p84)
          Length = 750

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 26/87 (29%), Positives = 36/87 (41%)
 Frame = +1

Query: 70  TLTCNPTLTLDIANTTTLPVVPNSGVPLFPPLP*RDYKIARHAHSPDNKSLKSVHFYSKP 249
           T  C P L +D+  TT+LPVV  S V   P                      S+ +Y+  
Sbjct: 437 TQLCQPGLVIDL-ETTSLPVVVISNVSQLP------------------SGWASILWYNM- 476

Query: 250 GSTLALRHRVSPFLTP*CSHWS*QKEV 330
              +A    +S FLTP C+ W+   EV
Sbjct: 477 --LVAEPRNLSFFLTPPCARWAQLSEV 501


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,661,724
Number of Sequences: 219361
Number of extensions: 2014510
Number of successful extensions: 4522
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 4370
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4511
length of database: 80,573,946
effective HSP length: 106
effective length of database: 57,321,680
effective search space used: 5101629520
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)