>LA_RAT (P38656) Lupus La protein homolog (La ribonucleoprotein) (La|
           autoantigen homolog)
          Length = 415

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 28/77 (36%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
 Frame = -3

Query: 568 REDFKEYFAKFGTVRYVDFSKGDDSGYLRFEEST--AVEKARAFAALADEGGLIMKGRLV 395
           REDF   F+  G ++++DF +G   G + F+E    A+EKAR+    A+ G L+++ + V
Sbjct: 245 REDFHFLFSNHGEIKWIDFVRGAKEGIILFKEKAKDALEKARS----ANNGNLLLRNKKV 300

Query: 394 TLEPVSGQAEKDYWSEI 344
           T + + G AEKD   +I
Sbjct: 301 TWKVLEGHAEKDAMKKI 317

>LA_MOUSE (P32067) Lupus La protein homolog (La ribonucleoprotein) (La|
           autoantigen homolog)
          Length = 415

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 27/77 (35%), Positives = 45/77 (58%), Gaps = 2/77 (2%)
 Frame = -3

Query: 568 REDFKEYFAKFGTVRYVDFSKGDDSGYLRFEEST--AVEKARAFAALADEGGLIMKGRLV 395
           RED    F+  G +++VDF++G   G + F+E    A+EKAR     A+ G L+++ + V
Sbjct: 245 REDLHFLFSNHGEIKWVDFARGAKEGIILFKEKAKEALEKARN----ANNGNLLLRNKKV 300

Query: 394 TLEPVSGQAEKDYWSEI 344
           T + + G AEK+   +I
Sbjct: 301 TWKVLEGHAEKEALKKI 317

>LAB_XENLA (P28049) Lupus La protein homolog B (La ribonucleoprotein B) (La|
           autoantigen homolog B)
          Length = 427

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
 Frame = -3

Query: 571 SREDFKEYFAKFGTVRYVDFSKGDDSGYLRFEEST--AVEKARAFAALADEGGLIMKGRL 398
           SRED    F   G + ++DFS+G   G + F+ +   A++KA+A    A+   L +KG+ 
Sbjct: 244 SREDLHALFQTHGEIEWIDFSRGAKEGIVLFKMNAKEALDKAKA----ANNDNLKLKGKN 299

Query: 397 VTLEPVSGQAEKDYWSEI 344
           V  E + G AEK+   +I
Sbjct: 300 VKWELIEGDAEKEALKKI 317

>LAA_XENLA (P28048) Lupus La protein homolog A (La ribonucleoprotein A) (La|
           autoantigen homolog A)
          Length = 428

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
 Frame = -3

Query: 571 SREDFKEYFAKFGTVRYVDFSKGDDSGYLRFEEST--AVEKARAFAALADEGGLIMKGRL 398
           SRED    F   G + ++DFS+G   G + F+ +   A++KA+A    A+   L +KG+ 
Sbjct: 245 SREDLHALFQTHGDIEWIDFSRGAKEGIVLFKMNAKEALDKAKA----ANSDNLKLKGKD 300

Query: 397 VTLEPVSGQAEKDYWSEI 344
           V  E + G  EK+   +I
Sbjct: 301 VKWELIEGDTEKEALKKI 318

>LA_HUMAN (P05455) Lupus La protein (Sjoegren syndrome type B antigen) (SS-B)|
           (La ribonucleoprotein) (La autoantigen)
          Length = 408

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/75 (30%), Positives = 41/75 (54%)
 Frame = -3

Query: 568 REDFKEYFAKFGTVRYVDFSKGDDSGYLRFEESTAVEKARAFAALADEGGLIMKGRLVTL 389
           RED    F+  G ++++DF +G   G + F+E    ++A   A  A+ G L ++ + VT 
Sbjct: 246 REDLHILFSNHGEIKWIDFVRGAKEGIILFKEK--AKEALGKAKDANNGNLQLRNKEVTW 303

Query: 388 EPVSGQAEKDYWSEI 344
           E + G+ EK+   +I
Sbjct: 304 EVLEGEVEKEALKKI 318

>LA_DROME (P40796) La protein homolog (La ribonucleoprotein) (La autoantigen|
           homolog)
          Length = 390

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
 Frame = -3

Query: 592 ENDKEPVSREDFKEYFAKFGT--VRYVDFSKGDDSGYLRFEESTAVEKARAFAALADEGG 419
           E   E  SRE+ +E F K     V Y++F+KG+  G +R  E+ A EK   + A  +EG 
Sbjct: 269 EGAPETSSREEIREAFEKIKDFEVAYIEFAKGETKGSVRLTEADAAEK---YIAKVEEGK 325

Query: 418 LIMKGRL-VTLEPVSGQAEKDY 356
           L  K  + ++L   + + EK++
Sbjct: 326 LKFKDEVSLSLRKATEEEEKEF 347

>LA_BOVIN (P10881) Lupus La protein homolog (La ribonucleoprotein) (La|
           autoantigen homolog)
          Length = 404

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
 Frame = -3

Query: 568 REDFKEYFAKFGTVRYVDFSKGDDSGYLRFEEST--AVEKARAFAALADEGGLIMKGRLV 395
           RED    F+  G ++++ F +G   G + F+E    A++KA+     A+ G L ++ + V
Sbjct: 246 REDLHTLFSNHGEIKWIHFVRGAKEGIILFKEKAKEALDKAKE----ANNGNLQLRNKEV 301

Query: 394 TLEPVSGQAEKDYWSEI 344
           T E + G  EK+   +I
Sbjct: 302 TWEVLEGDVEKEALKKI 318

>MRD1_NEUCR (Q7SG09) Multiple RNA-binding domain-containing protein 1|
          Length = 827

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
 Frame = -3

Query: 619 VKKDDKSPSENDKEPVSREDFKEYFAKFGTVRYVDF---SKGDDSGY--LRFEESTAVEK 455
           ++K  +    N    V+ +D +E+FAKFG +  V     SKG   G+  +R+E     + 
Sbjct: 304 IEKTSRLFLRNLSYTVTEDDVREHFAKFGILVEVHVPLDSKGHSKGFAMIRYE-----KP 358

Query: 454 ARAFAALADEGGLIMKGRLVTLEPVSGQAE 365
           A A AA   + G + +GR+V + P + + E
Sbjct: 359 ASALAAFQTD-GTVFQGRIVHILPAAAKRE 387

>RBM15_HUMAN (Q96T37) Putative RNA-binding protein 15 (RNA-binding motif protein|
           15) (One-twenty two protein)
          Length = 977

 Score = 33.9 bits (76), Expect = 0.41
 Identities = 13/32 (40%), Positives = 20/32 (62%)
 Frame = -3

Query: 547 FAKFGTVRYVDFSKGDDSGYLRFEESTAVEKA 452
           F +FGT+R +D+ KGD   Y+++E   A   A
Sbjct: 475 FDRFGTIRTIDYRKGDSWAYIQYESLDAAHAA 506

>SFPQ_MOUSE (Q8VIJ6) Splicing factor, proline- and glutamine-rich|
           (Polypyrimidine tract-binding protein-associated
           splicing factor) (PTB-associated splicing factor) (PSF)
           (DNA-binding p52/p100 complex, 100 kDa subunit)
          Length = 699

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 14/43 (32%), Positives = 24/43 (55%)
 Frame = -3

Query: 574 VSREDFKEYFAKFGTVRYVDFSKGDDSGYLRFEESTAVEKARA 446
           ++ ++FK  FAK+G    V  +KG   G+++ E     E A+A
Sbjct: 300 ITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKA 342

>SFPQ_HUMAN (P23246) Splicing factor, proline- and glutamine-rich|
           (Polypyrimidine tract-binding protein-associated
           splicing factor) (PTB-associated splicing factor) (PSF)
           (DNA-binding p52/p100 complex, 100 kDa subunit) (100-kDa
           DNA-pairing protein) (hPOMp
          Length = 707

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 14/43 (32%), Positives = 24/43 (55%)
 Frame = -3

Query: 574 VSREDFKEYFAKFGTVRYVDFSKGDDSGYLRFEESTAVEKARA 446
           ++ ++FK  FAK+G    V  +KG   G+++ E     E A+A
Sbjct: 308 ITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKA 350

>RB15B_HUMAN (Q8NDT2) Putative RNA-binding protein 15B (RNA-binding motif|
           protein 15B)
          Length = 563

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = -3

Query: 547 FAKFGTVRYVDFSKGDDSGYLRFEESTAVEKARA 446
           F +FG++R +D  KGD   Y+++E   A + A A
Sbjct: 111 FDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACA 144

>GLYA_METJA (Q58992) Serine hydroxymethyltransferase (EC 2.1.2.1) (Serine|
           methylase) (SHMT)
          Length = 429

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 15/38 (39%), Positives = 22/38 (57%)
 Frame = -3

Query: 592 ENDKEPVSREDFKEYFAKFGTVRYVDFSKGDDSGYLRF 479
           + +K    RED KE+  ++ T+ Y  F +GD   YLRF
Sbjct: 392 DKEKPEKVREDVKEFAKEYSTIHY-SFDEGDGFKYLRF 428

>RB15B_MOUSE (Q6PHZ5) Putative RNA-binding protein 15B (RNA-binding motif|
           protein 15B)
          Length = 564

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 13/34 (38%), Positives = 21/34 (61%)
 Frame = -3

Query: 547 FAKFGTVRYVDFSKGDDSGYLRFEESTAVEKARA 446
           F +FG++R +D  KGD   Y+++E   A + A A
Sbjct: 111 FDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACA 144

>LA_AEDAL (Q26457) La protein homolog (La ribonucleoprotein) (La autoantigen|
           homolog)
          Length = 383

 Score = 28.5 bits (62), Expect(2) = 1.7
 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
 Frame = -3

Query: 571 SREDFKEYFAKFGT---VRYVDFSKGDDSGYLRFEESTAVEKARAFAALADEGGLIMKGR 401
           SRE  KE   K      V ++D++K D  G +RF    A +K   F     +  + +   
Sbjct: 266 SRETIKETILKLDESLEVAFIDYAKTDTEGTVRFAADDAGKK---FMEKLTDSKIQIDEE 322

Query: 400 LVTLEPVSGQAEKDYWSEI 344
            +T   + G  EK++  ++
Sbjct: 323 EITARLLEGDEEKEFLRKV 341



 Score = 21.9 bits (45), Expect(2) = 1.7
 Identities = 8/16 (50%), Positives = 10/16 (62%)
 Frame = -2

Query: 302 QGRKGLEEQQRWRRKA 255
           +GR+     Q WRRKA
Sbjct: 362 EGRQASRPPQEWRRKA 377

>NAM8_YEAST (Q00539) Protein NAM8|
          Length = 523

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 13/43 (30%), Positives = 24/43 (55%)
 Frame = -3

Query: 574 VSREDFKEYFAKFGTVRYVDFSKGDDSGYLRFEESTAVEKARA 446
           V+ ++ + YF  FGT+ YV    G   G++++ +  + E A A
Sbjct: 324 VTEDELRAYFQPFGTIVYVKIPVGKCCGFVQYVDRLSAEAAIA 366

>SYS_SULTO (Q970Y4) Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase)|
           (SerRS)
          Length = 453

 Score = 30.4 bits (67), Expect = 4.6
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 6/82 (7%)
 Frame = -3

Query: 583 KEPVSREDFKEYFAKFGTVRYVDFSKGDDSGYLRFEESTAVEKARAFAALAD----EGGL 416
           +E VS  +  ++ A    +RYV+  KG   GY+    STA+   R   A+ +    E G+
Sbjct: 369 REMVSCSNCLDWQAYRMRIRYVE--KGGKKGYVHTLNSTAIASTRTITAILENYQREDGV 426

Query: 415 IMKGRLVT--LEPVSGQAEKDY 356
           +   +++   LEP S +A KDY
Sbjct: 427 VEIPKVLKKYLEPFS-RAPKDY 447

>ROAA_MOUSE (Q99020) Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B)|
           (CArG-binding factor-A) (CBF-A)
          Length = 285

 Score = 29.6 bits (65), Expect = 7.8
 Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 8/47 (17%)
 Frame = -3

Query: 571 SREDFKEYFAKFGTVRYVDFS--------KGDDSGYLRFEESTAVEK 455
           S++D K+YF KFG V  VD +        +    G++ F++S++VEK
Sbjct: 87  SKKDLKDYFTKFGEV--VDCTIKMDPNTGRSRGFGFILFKDSSSVEK 131


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,974,991
Number of Sequences: 219361
Number of extensions: 1713994
Number of successful extensions: 4776
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 4599
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4771
length of database: 80,573,946
effective HSP length: 107
effective length of database: 57,102,319
effective search space used: 5881538857
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)