ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal7p12 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 245 bits (626), Expect = 7e-65 Identities = 116/142 (81%), Positives = 128/142 (90%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VISLHPVLDKTT+HL+N E L MKK+A+L+N SRGPVIDE ALV+HL+ NPMFRVGLDV Sbjct: 239 VISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDV 298 Query: 446 FEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEP 267 FEDEPYMKPGLA+MKNA++VPHIASASKWTREGMATLAALNVLGKIKGYPVW +PN VEP Sbjct: 299 FEDEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEP 358 Query: 266 FLDEEATPPPACPSIVNAKQLG 201 FLDE +PP A PSIVNAK LG Sbjct: 359 FLDENVSPPAASPSIVNAKALG 380
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 103 bits (256), Expect = 5e-22 Identities = 53/107 (49%), Positives = 69/107 (64%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ISLH L K TYH+I + L +MK A+L+N SRG V+D AL++ LK + GLDVF Sbjct: 208 ISLHVPLTKETYHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDVF 267 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 E+EPY L ++KN V+ PHI SA+ REGMA L A N++ KG Sbjct: 268 EEEPYYNEELFKLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKG 314
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 99.8 bits (247), Expect = 6e-21 Identities = 52/101 (51%), Positives = 67/101 (66%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L + TYHLIN ERL +MKK A+L+N +RG V+D ALV+ LK + GLDVFE+EPY Sbjct: 214 LTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPYY 273 Query: 425 KPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 L ++ N V+ PHI SAS REGMA L A N++ +G Sbjct: 274 NEELFKLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRG 314
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 98.6 bits (244), Expect = 1e-20 Identities = 50/101 (49%), Positives = 67/101 (66%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L+K TYH+IN ERL MMK+ A+L+N +RG VID AL++ LK + GLDV+E+EPY Sbjct: 215 LNKETYHMINEERLKMMKRTAILINVARGKVIDTKALIKALKEGWIAGAGLDVYEEEPYY 274 Query: 425 KPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 L + N V+ PHI SA+ REGMA L A N++ +G Sbjct: 275 NEELFSLDNVVLTPHIGSATFGAREGMAKLVAENLIAFKRG 315
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 93.6 bits (231), Expect = 4e-19 Identities = 48/96 (50%), Positives = 64/96 (66%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L K T ++IN ERL +MKK A+LVN +RG V+D AL++ LK + GLDV+E+EPY Sbjct: 214 LTKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYEEEPYY 273 Query: 425 KPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 318 L +KN V+ PHI SA+ REGMA L A N++ Sbjct: 274 NEELFSLKNVVLAPHIGSATYGAREGMAELVARNLI 309
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 88.6 bits (218), Expect = 1e-17 Identities = 47/101 (46%), Positives = 63/101 (62%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L K T ++IN ERL +MK A+LVN +RG V+D AL++ LK + GLDVFE+EPY Sbjct: 214 LTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYY 273 Query: 425 KPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 L + N V+ PHI SA+ RE MA L A N++ +G Sbjct: 274 NEELFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRG 314
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 86.7 bits (213), Expect = 5e-17 Identities = 47/102 (46%), Positives = 63/102 (61%), Gaps = 1/102 (0%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY- 429 L + T+H+I E+LA MK A+L+NA RGPV+DE AL+ LK + GLDVFE EP Sbjct: 209 LTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALKDKTIHAAGLDVFEQEPLP 268 Query: 428 MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 + L + N V +PHI SA+ TR GMA A N++ + G Sbjct: 269 VDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLIAALAG 310
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 86.3 bits (212), Expect = 7e-17 Identities = 47/104 (45%), Positives = 63/104 (60%), Gaps = 1/104 (0%) Frame = -2 Query: 611 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 432 P+ D+T +HL E+ A MK A+ +NA RGPV+DE AL+ L+ + GLDVFE EP Sbjct: 209 PLTDET-HHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEP 267 Query: 431 Y-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 + L M N V VPHI SA+ TR GMA A N++ ++G Sbjct: 268 LSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQG 311
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 86.3 bits (212), Expect = 7e-17 Identities = 47/104 (45%), Positives = 63/104 (60%), Gaps = 1/104 (0%) Frame = -2 Query: 611 PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEP 432 P+ D+T +HL E+ A MK A+ +NA RGPV+DE AL+ L+ + GLDVFE EP Sbjct: 209 PLTDET-HHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEP 267 Query: 431 Y-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 + L M N V VPHI SA+ TR GMA A N++ ++G Sbjct: 268 LSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQG 311
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 81.6 bits (200), Expect = 2e-15 Identities = 47/110 (42%), Positives = 66/110 (60%), Gaps = 2/110 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++S+H L T HLI L +MKK A+LVN RG ++D ALV+ L+ + LDV Sbjct: 208 ILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAALDV 267 Query: 446 FEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 FE+EP + P L KN V+ PH ASA++ TR MA +AA N++ +G Sbjct: 268 FEEEP-LNPNHPLTAFKNVVLAPHAASATRETRLRMAMMAAENLVAFAQG 316
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/102 (40%), Positives = 61/102 (59%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+SL+ L+ T H+I MK+ V+VN +RG V+DE ALVE L ++ GLDV Sbjct: 212 VLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSAGLDV 271 Query: 446 FEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 321 FE+EP + PGL E + +++PH+ + S T+ M +NV Sbjct: 272 FEEEPKIHPGLLENEKVILLPHLGTNSLETQYKMECAVLMNV 313
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 76.3 bits (186), Expect = 7e-14 Identities = 46/135 (34%), Positives = 70/135 (51%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++S++ L+ T+HLIN E + MK V+VN +RG VIDE A+ + L++ + GLDV Sbjct: 220 IVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGLDV 279 Query: 446 FEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEP 267 FE EP + L M + +PH+ + S TR+ M L N K + G + P Sbjct: 280 FEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVENA----KNVILTGKVLTIVP 335 Query: 266 FLDEEATPPPACPSI 222 L E P + P + Sbjct: 336 ELQNEDWPNESKPLV 350
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 75.1 bits (183), Expect = 2e-13 Identities = 39/107 (36%), Positives = 62/107 (57%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I+LH L T H+I E++A+MKK A++VN +RG +IDE AL E LK + LDVF Sbjct: 198 ITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRAAALDVF 257 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 E+EP L + N + PH ++++ ++ T+ A + ++G Sbjct: 258 EEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVLRG 304
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 74.7 bits (182), Expect = 2e-13 Identities = 56/144 (38%), Positives = 76/144 (52%), Gaps = 3/144 (2%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 +SLH L T + N E + MKK L+N +RG VIDE ALV L A + + LDVF Sbjct: 279 VSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAALDVF 338 Query: 443 EDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA--V 273 +EP K L + +N V PH+ +++K +EG+A A V G +KG NA V Sbjct: 339 CEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGELSATAVNAPMV 398 Query: 272 EPFLDEEATPPPACPSIVNAKQLG 201 P + E T P IV A++LG Sbjct: 399 APEVLSELT-----PYIVLAEKLG 417
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 74.3 bits (181), Expect = 3e-13 Identities = 41/109 (37%), Positives = 62/109 (56%), Gaps = 1/109 (0%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++ + P+ D+T YH+I +MK A+ VN SRG +DE AL+ L+ + GLDV Sbjct: 207 ILLITPLTDET-YHMIGEREFKLMKNSAIFVNISRGKTVDEKALIRALQEGWIRGAGLDV 265 Query: 446 FEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 +E EP + L ++ N ++PHI SA+ R M AA N+L I+G Sbjct: 266 YEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQG 314
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 73.2 bits (178), Expect = 6e-13 Identities = 54/145 (37%), Positives = 77/145 (53%), Gaps = 3/145 (2%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++++H L T HLI+ + +MK A +VN +RG +IDE AL LK + LDV Sbjct: 198 IVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALKDGEIAGAALDV 257 Query: 446 FEDEPYMKPGLAEMKNAVVVPHI-ASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV- 273 FE+EP L E++N V+ PHI AS S+ R+ AA+ V +IK G P V Sbjct: 258 FEEEPPEGSPLLELENVVLTPHIGASTSEAQRD-----AAIIVANEIKTVFQGGAPRNVL 312 Query: 272 -EPFLDEEATPPPACPSIVNAKQLG 201 P +D E T P I A+++G Sbjct: 313 NMPVMDSE-TYKSLKPYIELAEKMG 336
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/130 (34%), Positives = 66/130 (50%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +I++H L K T L+N E +A KK L+N +RG +IDE AL+E L+ + LDV Sbjct: 195 IITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENGHVAGAALDV 254 Query: 446 FEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEP 267 FE EP + L + + PH+ +++K + +A + VL KG PV N Sbjct: 255 FEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKGLPVMSAINLPAM 314 Query: 266 FLDEEATPPP 237 DE A P Sbjct: 315 TKDEFAKIKP 324
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 70.9 bits (172), Expect = 3e-12 Identities = 42/123 (34%), Positives = 67/123 (54%), Gaps = 3/123 (2%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI++H K T LI + MK ++VNA+RG ++DE AL E +KA + LDV Sbjct: 196 VITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAALYEAIKAGKVAAAALDV 255 Query: 446 FEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPN--A 276 +E EP L ++ N V PHIA++++ + + + A +++ KG PV N + Sbjct: 256 YEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIVNMAKGLPVRNAVNLPS 315 Query: 275 VEP 267 +EP Sbjct: 316 IEP 318
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 70.9 bits (172), Expect = 3e-12 Identities = 41/92 (44%), Positives = 53/92 (57%), Gaps = 5/92 (5%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +++LH L +TT LIN E L+ MKK A L+N RGP+IDE+ALV+ LK + LDV Sbjct: 199 IVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGHLGGAALDV 258 Query: 446 FEDEPYMKP-----GLAEMKNAVVVPHIASAS 366 EP K M N ++ PHIA AS Sbjct: 259 MVKEPPEKDNPLILAAKTMPNLIITPHIAWAS 290
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 70.1 bits (170), Expect = 5e-12 Identities = 41/113 (36%), Positives = 62/113 (54%), Gaps = 3/113 (2%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI+LH L T ++I E+L MK+ A+L+N +RG ++DE AL++ LK + G DV Sbjct: 195 VITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKDGTIGGAGFDV 254 Query: 446 FEDEPYMKPGL---AEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 297 EP + A++ N +V PH+A ASK + +A NV + G P Sbjct: 255 VAQEPPKDGNILCDADLPNLIVTPHVAWASKEAMQILADQLVDNVEAFVAGKP 307
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 67.0 bits (162), Expect = 4e-11 Identities = 40/105 (38%), Positives = 58/105 (55%), Gaps = 1/105 (0%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY- 429 L T L N + MK+ AV +N SRG V+++ L + L + + GLDV EP Sbjct: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLP 277 Query: 428 MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 294 L +KN V++PHI SA+ TR M+ LAA N+L ++G P+ Sbjct: 278 TNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 66.6 bits (161), Expect = 6e-11 Identities = 38/109 (34%), Positives = 58/109 (53%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I+LH T +LIN E LA MK A ++N SRG +IDE ALV ++ + LDVF Sbjct: 225 ITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETAQIGGAALDVF 284 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 297 EP + L E N ++ PH+ ++++ + +A A + + G P Sbjct: 285 AQEPLGESRLREFSNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLGLP 333
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/127 (33%), Positives = 65/127 (51%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 IS+H T LI+ E LA K ++VNA+RG ++DEVAL + +++ + GLDVF Sbjct: 199 ISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGLDVF 258 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEPF 264 EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 259 ATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVDGGV 318 Query: 263 LDEEATP 243 ++EE P Sbjct: 319 VNEEVAP 325
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 63.2 bits (152), Expect = 6e-10 Identities = 54/167 (32%), Positives = 79/167 (47%), Gaps = 22/167 (13%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + LK + LDV Sbjct: 239 VSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVH 298 Query: 443 EDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLAALNVLGKI--------- 309 E EP + + L + N + PH A AS RE AT + G+I Sbjct: 299 ESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVN 358 Query: 308 KGYPVWGNPNAVEPFLDEEATPPPA-------CPSIVNAKQLGLPSS 189 K + V P +V +D++A P P IV GLP++ Sbjct: 359 KEFFVTSAPWSV---IDQQAIHPELNGATYRYPPGIVGVAPGGLPAA 402
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 62.8 bits (151), Expect = 8e-10 Identities = 39/99 (39%), Positives = 59/99 (59%), Gaps = 4/99 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +++ H L+K+ T+HL++ E L+++ +L+NASRG VID AL+ LK RV Sbjct: 170 ILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLTALKCGKKLRV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + L E+ + + PHIA +T EG A Sbjct: 230 VLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 62.8 bits (151), Expect = 8e-10 Identities = 41/111 (36%), Positives = 59/111 (53%), Gaps = 6/111 (5%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + LK + LDV Sbjct: 239 VSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVH 298 Query: 443 EDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLAALNVLGKI 309 E EP + + L + N + PH A AS RE AT + G+I Sbjct: 299 ESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRI 349
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/116 (31%), Positives = 58/116 (50%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LDVF Sbjct: 202 ITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLRALQSGQCAGAALDVF 261 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 +EP L +N + PH+ +++K + AL + +KG + G NA Sbjct: 262 TEEPPRDRALVNHENVISCPHLGASTKEAQSRCGEEIALQFVDMVKGKALAGVVNA 317
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/127 (32%), Positives = 62/127 (48%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + GLDVF Sbjct: 199 ISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVF 258 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEPF 264 EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 259 ATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVGGGV 318 Query: 263 LDEEATP 243 ++EE P Sbjct: 319 VNEEVAP 325
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/127 (32%), Positives = 62/127 (48%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + GLDVF Sbjct: 199 ISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVF 258 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVEPF 264 EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 259 ATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVGGGV 318 Query: 263 LDEEATP 243 ++EE P Sbjct: 319 VNEEVAP 325
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/103 (36%), Positives = 57/103 (55%), Gaps = 2/103 (1%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L T L + + MK A+ +N SRG V+++ L + L + + GLDV EP + Sbjct: 218 LTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGLDVTTPEP-L 276 Query: 425 KPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 P L +KN V++PHI SA+ TR M+ LAA N+L ++G Sbjct: 277 PPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRG 319
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LDVF Sbjct: 202 ITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVF 261 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 262 TEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LDVF Sbjct: 202 ITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVF 261 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 262 TEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LDVF Sbjct: 202 ITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVF 261 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 262 TEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LDVF Sbjct: 202 ITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVF 261 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 262 TEEPPRGRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 61.2 bits (147), Expect = 2e-09 Identities = 35/116 (30%), Positives = 59/116 (50%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LDVF Sbjct: 202 ITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVF 261 Query: 443 EDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 262 TEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLAGVVNA 317
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 60.8 bits (146), Expect = 3e-09 Identities = 44/142 (30%), Positives = 68/142 (47%), Gaps = 5/142 (3%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 +SLH L++ +HLIN + M+ A LVN +RG ++D+ L LK + LDV Sbjct: 233 VSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAALDVH 292 Query: 443 EDEPY--MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAVE 270 E+EPY + L + N + PH A S + + +AA + I G P+ + Sbjct: 293 ENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVG----NIPDVLR 348 Query: 269 PFLDEE---ATPPPACPSIVNA 213 +++E TPP A V A Sbjct: 349 NCVNKEYFMRTPPAAAAGGVAA 370
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 8/109 (7%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L+ T HL+N E LA+++ A+LVN RG V+DE A++ L+ + DVFE E + Sbjct: 210 LNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAALERGQLGGYAADVFEMEDWA 269 Query: 425 K--------PGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 + P L N + PHI SA + R + AA N++ + G Sbjct: 270 RADRPRLIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAAQNIIQVLAG 318
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/115 (33%), Positives = 61/115 (53%), Gaps = 6/115 (5%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+SLH +T +L+N R+A +K+ A+L+NA+RG V+D AL + LK + +DV Sbjct: 207 VVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDALAQALKDGKLQGAAIDV 266 Query: 446 FEDEP------YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 F EP ++ P L E N ++ PHI ++ +E + V GK Y Sbjct: 267 FPVEPASINEEFISP-LREFDNVILTPHIGGSTAEAQENI----GFEVAGKFVKY 316
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/91 (43%), Positives = 52/91 (57%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VISLH L + T+HL+ +LA ++ A LVNASRGPV+D VAL E L Sbjct: 169 VISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVDNVALRELLLDREDVHA 228 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP + LA++ + PHIA S Sbjct: 229 VLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 59.7 bits (143), Expect = 7e-09 Identities = 37/91 (40%), Positives = 54/91 (59%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VISLH LDK+ T+HL++ RL +++ A L+NASRG V+D AL + + + Sbjct: 169 VISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVVDNRALHDVMLEREDLQA 228 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP + LA++ + PHIA S Sbjct: 229 VLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 59.3 bits (142), Expect = 9e-09 Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 4/88 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL L+ F Sbjct: 171 VITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQALKHRLQQADGFTA 230 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP + L + A PH+A Sbjct: 231 ALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 59.3 bits (142), Expect = 9e-09 Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 4/88 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL L+ F Sbjct: 171 VITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQALKRRLQQADGFMA 230 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP + L + A PH+A Sbjct: 231 ALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 59.3 bits (142), Expect = 9e-09 Identities = 39/91 (42%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VISLH L++ T HL++ RLA ++ LVNASRG V+D AL L+ V Sbjct: 170 VISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRLLEGGADLEV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP P LA + + PHIA S Sbjct: 230 ALDVWEGEPQADPELA-ARCLIATPHIAGYS 259
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/115 (31%), Positives = 63/115 (54%), Gaps = 6/115 (5%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + +DV Sbjct: 205 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDV 264 Query: 446 FEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 F E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 265 FPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/115 (31%), Positives = 63/115 (54%), Gaps = 6/115 (5%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + +DV Sbjct: 205 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDV 264 Query: 446 FEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 F E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 265 FPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/115 (31%), Positives = 63/115 (54%), Gaps = 6/115 (5%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + +DV Sbjct: 205 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDV 264 Query: 446 FEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 F E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 265 FPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/115 (31%), Positives = 63/115 (54%), Gaps = 6/115 (5%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + +DV Sbjct: 205 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDV 264 Query: 446 FEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 F E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 265 FPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/96 (37%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L TY ++N E L MK AVLVN RGP+I+ LV+ L + LDV + EP Sbjct: 190 LTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGTIAGAALDVTDPEPLP 249 Query: 425 -KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 321 L EM N V+ PH A+ ++ R L N+ Sbjct: 250 DSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + LDV Sbjct: 233 VTLHCGLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVH 292 Query: 443 EDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 E EP + + L + N + PH A S+ M AA + I G Sbjct: 293 ESEPFSFTQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + LDV Sbjct: 233 VTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVH 292 Query: 443 EDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 E EP + + L + N + PH A S+ M AA + I G Sbjct: 293 ESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + LDV Sbjct: 233 VTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVH 292 Query: 443 EDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 E EP + + L + N + PH A S+ M AA + I G Sbjct: 293 ESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + LDV Sbjct: 222 VTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVH 281 Query: 443 EDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 E EP + + L + N + PH A S+ M AA + I G Sbjct: 282 ESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 330
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 57.4 bits (137), Expect = 3e-08 Identities = 43/126 (34%), Positives = 62/126 (49%), Gaps = 6/126 (4%) Frame = -2 Query: 626 VISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D AL L+ F Sbjct: 171 VITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALKARLQQGDGFTA 230 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLGKIKGYPVWGN 285 LDVFE EP + L + A PHIA + EG A T N + G N Sbjct: 231 VLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKARGTTMIFNSYCEFLGSAHCAN 286 Query: 284 PNAVEP 267 P ++ P Sbjct: 287 PASLLP 292
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 57.4 bits (137), Expect = 3e-08 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = -2 Query: 605 LDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYM 426 L TY ++N E L MK AV+VN RGP+I+ LV+ L + LDV + EP Sbjct: 190 LTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGTIAGAALDVTDPEPLP 249 Query: 425 -KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 321 L EM N V+ PH A+ ++ R L N+ Sbjct: 250 DSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 57.0 bits (136), Expect = 4e-08 Identities = 30/93 (32%), Positives = 48/93 (51%) Frame = -2 Query: 620 SLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 441 SL+ T + N + + + A++VN +RG ++D +V L+A + G DVF Sbjct: 208 SLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFA 267 Query: 440 DEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 EP + G ++ N + PHI SA+ RE MA Sbjct: 268 GEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 300
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 56.2 bits (134), Expect = 8e-08 Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 14/122 (11%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VISLH H+IN + +A MK++ V+VN SRGP++D A++ L + +F +DV Sbjct: 201 VISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKVFGYAMDV 260 Query: 446 FEDE-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKI 309 +E E + LA++ N +V PH A + M A N L + Sbjct: 261 YEGEVGVFNEDREGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNLELV 320 Query: 308 KG 303 +G Sbjct: 321 EG 322
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 56.2 bits (134), Expect = 8e-08 Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 4/88 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D AL + L F Sbjct: 171 IITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQALKQRLMKQDGFTA 230 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP + L + A PH+A Sbjct: 231 ALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +I+LH L + T+HLIN + L +K +L+N SRG VID +L+ LK RV Sbjct: 169 IITLHVPLTYSGKYPTWHLINKKILLDLKDNCILINTSRGSVIDNNSLLNILKEGKPIRV 228 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E+EP + L + + + PHIA S Sbjct: 229 VLDVWENEPLICSKLLSLID-IGTPHIAGHS 258
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/64 (43%), Positives = 38/64 (59%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VISLH L YHL+N MK ++VN SRG +ID A +E LK + +G+DV Sbjct: 200 VISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDV 259 Query: 446 FEDE 435 +E+E Sbjct: 260 YENE 263
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 55.1 bits (131), Expect = 2e-07 Identities = 40/92 (43%), Positives = 53/92 (57%), Gaps = 4/92 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 ++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL L+ + + Sbjct: 170 LVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCDHVITC 226 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 363 LDV+E+EP + L E K + PHIA SK Sbjct: 227 -LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 2/85 (2%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 I+LH L++ +HLIN + M++ LVN +RG ++DE AL + LK + LDV Sbjct: 236 ITLHCNLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKDGRIRGAALDVH 295 Query: 443 EDEP--YMKPGLAEMKNAVVVPHIA 375 E EP + + L + N + PH A Sbjct: 296 ESEPFSFSQGPLKDAPNLICTPHTA 320
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/108 (34%), Positives = 51/108 (47%), Gaps = 14/108 (12%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VISLH K ++HLIN + +A MK LVN +RG VID AL++ L + LD Sbjct: 201 VISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALLDSLDKGKIAGAALDA 260 Query: 446 FEDE-PYMKPG-------------LAEMKNAVVVPHIASASKWTREGM 345 +E E PY+ L + + PHIA ++ E M Sbjct: 261 YEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETAIENM 308
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/64 (43%), Positives = 39/64 (60%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH L +H+IN E LA KK LVN SRG ++D A+++ LKA + DV Sbjct: 202 IISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVDTKAVIKSLKAKHLGGYAADV 261 Query: 446 FEDE 435 +E+E Sbjct: 262 YEEE 265
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/64 (42%), Positives = 39/64 (60%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI+LH YHL+N E A MK ++VN SRG +ID A ++ LK + +G+DV Sbjct: 200 VITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALGMDV 259 Query: 446 FEDE 435 +E+E Sbjct: 260 YENE 263
>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 4/99 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 V++ H L K T HL + + +K A+L+NA RGPV+D AL+ L A V Sbjct: 170 VLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPLSV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + L E + + HIA +T EG A Sbjct: 230 VLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.5 bits (127), Expect = 5e-07 Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 4/99 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 V++ H L K T HL + + +K A+L+NA RGPV+D AL+ L A V Sbjct: 170 VLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPLSV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + L E + + HIA +T EG A Sbjct: 230 VLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 53.1 bits (126), Expect = 6e-07 Identities = 28/90 (31%), Positives = 47/90 (52%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VIS++ L T+ LI+ + MK ++N +RG +I+E A ++ +K+ + R GLDV Sbjct: 217 VISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGLDV 276 Query: 446 FEDEPYMKPGLAEMKNAVVVPHIASASKWT 357 F +EP E + PH + +T Sbjct: 277 FLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 52.8 bits (125), Expect = 8e-07 Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +++LH L+ T+++I+ E++ MK+ A L+N RGP++D LV+ L+ + LDV Sbjct: 197 IVTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDV 256 Query: 446 FEDEP-------YMKP-------GLAEMKNAVVVPHIA 375 E E KP L M N ++ PH A Sbjct: 257 LEGEEEFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTA 294
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/100 (37%), Positives = 54/100 (54%), Gaps = 5/100 (5%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 V++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ L+ V Sbjct: 170 VLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKKLSV 229 Query: 458 GLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + P LA + + PHIA +T EG A Sbjct: 230 VLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 52.0 bits (123), Expect = 1e-06 Identities = 37/100 (37%), Positives = 54/100 (54%), Gaps = 5/100 (5%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 V++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ L+ V Sbjct: 170 VLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKKLSV 229 Query: 458 GLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + P LA + + PHIA +T EG A Sbjct: 230 VLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 50.8 bits (120), Expect = 3e-06 Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 13/100 (13%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 +SLH T ++I+ + A MK+ + L+NASRG V+D ALV+ K+ + +DV+ Sbjct: 251 VSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALVDASKSGKIAGAAIDVY 310 Query: 443 EDEP-------------YMKPGLAEMKNAVVVPHIASASK 363 EP L KN ++ PHI +++ Sbjct: 311 PSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 15/99 (15%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +++LH L T HLI ++ MK+ A L+N RG ++D +LVE L + + LDV Sbjct: 198 IVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSGKLGGAALDV 257 Query: 446 FE---------------DEPYMKPGLAEMKNAVVVPHIA 375 E D P++ L M N ++ PH A Sbjct: 258 LEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 50.4 bits (119), Expect = 4e-06 Identities = 38/122 (31%), Positives = 55/122 (45%), Gaps = 14/122 (11%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VISLH H+IN + +A MK V+VN SRG ++D A++ L + +F +D Sbjct: 201 VISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMDT 260 Query: 446 FEDE-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLGKI 309 +EDE + LA++ N +V PH A + M A N L I Sbjct: 261 YEDEVGVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNLKLI 320 Query: 308 KG 303 G Sbjct: 321 NG 322
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 50.1 bits (118), Expect = 5e-06 Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 4/99 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +++ H L K T HL + + + +K A+L+NA RG V+D AL+ L V Sbjct: 170 ILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + L + K + PHIA +T EG A Sbjct: 230 VLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 50.1 bits (118), Expect = 5e-06 Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +ISLH + +T T HL + RL +K L+N RG VID AL++ + ++ Sbjct: 171 IISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVIDNQALIKVKQQRDDLKL 230 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP P L PHIA S Sbjct: 231 VLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 49.7 bits (117), Expect = 7e-06 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 14/101 (13%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ++LH T +++ + A MK A ++NASRG V+D +L++ +KAN + LDV+ Sbjct: 254 VTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVY 313 Query: 443 EDEPYMKPG--------------LAEMKNAVVVPHIASASK 363 EP K G L + N ++ PHI +++ Sbjct: 314 PHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 49.7 bits (117), Expect = 7e-06 Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 14/101 (13%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ++LH T +++ + A MK A ++NASRG V+D +L++ +KAN + LDV+ Sbjct: 254 VTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVY 313 Query: 443 EDEPYMKPG--------------LAEMKNAVVVPHIASASK 363 EP K G L + N ++ PHI +++ Sbjct: 314 PHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 49.7 bits (117), Expect = 7e-06 Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 9/93 (9%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN----- 474 VI++H + K T+HLIN + ++ +A+L+NA+RGPV D AL + L+ + Sbjct: 171 VITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQALKKALQLSQSGLG 230 Query: 473 PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP++ L + A PHIA Sbjct: 231 KKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 49.3 bits (116), Expect = 9e-06 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 15/99 (15%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + + +D Sbjct: 201 IISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNNGTLSGAAIDT 260 Query: 446 FE---------------DEPYMKPGLAEMKNAVVVPHIA 375 +E D+P + L +N +V PHIA Sbjct: 261 YENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 49.3 bits (116), Expect = 9e-06 Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 15/99 (15%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + + +D Sbjct: 201 IISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNNGTLSGAAIDT 260 Query: 446 FE---------------DEPYMKPGLAEMKNAVVVPHIA 375 +E D+P + L +N +V PHIA Sbjct: 261 YENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 49.3 bits (116), Expect = 9e-06 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +++ H L K T HL + + + +K A+L+NA RG V+D AL+ L V Sbjct: 170 ILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + L K + PHIA +T EG A Sbjct: 230 VLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 49.3 bits (116), Expect = 9e-06 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +++ H L K T HL + + + +K A+L+NA RG V+D AL+ L V Sbjct: 170 ILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + L K + PHIA +T EG A Sbjct: 230 VLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VISLH + KT T++L + RL +K+ L+N RG VID AL++ P ++ Sbjct: 57 VISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVIDNQALIKVKLERPDIKL 116 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP L + + PHIA S Sbjct: 117 VLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K +YHL + +KK A+LVNA+RG VI+ L++ + + +D Sbjct: 201 IISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVNDGTLLGAAIDT 260 Query: 446 FEDEPYMKPG--------------LAEMKNAVVVPHIA 375 +E+E L E + +V PHIA Sbjct: 261 YENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)| Length = 379 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Frame = -2 Query: 593 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL 414 T HLIN + L +LVN RG ++D A+ + L + +GLDVF EP + + Sbjct: 270 TEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINHLGLDVFNKEPEIDEKI 329 Query: 413 AEMKNAV-VVPHIASASKWTREGMATLAALNVLGKIKG 303 + PH+ SA+K E LA +L + G Sbjct: 330 RSSDRLTSITPHLGSATKDVFEQSCELALTRILRVVSG 367
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 15/99 (15%) Frame = -2 Query: 626 VISLH-PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 VI LH P +++ T H+IN +MK A+++N +R +ID A++ +LK+ + VG+D Sbjct: 200 VIDLHVPGIEQNT-HIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGID 258 Query: 449 VFEDEPYMKPGLAE--------------MKNAVVVPHIA 375 +E E LA+ M N V+ PHIA Sbjct: 259 TYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/97 (31%), Positives = 52/97 (53%), Gaps = 14/97 (14%) Frame = -2 Query: 623 ISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVF 444 ISL+ +HLIN + +A MK V++NA+RG ++D A+++ L + + G+DV+ Sbjct: 202 ISLYVPGVPENHHLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFGMDVY 261 Query: 443 EDEP--YMKPGLAE------------MKNAVVVPHIA 375 E+E MK GL + +N ++ PH A Sbjct: 262 ENEVACSMKIGLVKNSPDAKIADLIARENVMITPHTA 298
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/91 (37%), Positives = 48/91 (52%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 VISLH + KT T++L + RL +K L+N RG VID AL++ + P ++ Sbjct: 57 VISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVIDNRALIKVKQQRPDIKL 116 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP L + + PHIA S Sbjct: 117 VLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/84 (36%), Positives = 44/84 (52%) Frame = -2 Query: 593 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL 414 T+HL++ L +L+NA RGPV+D AL+E L+ V LDV+E EP + L Sbjct: 185 THHLVDATVLNAFADGRILINACRGPVVDNAALLEALQQGKKLSVILDVWEPEPGLSTDL 244 Query: 413 AEMKNAVVVPHIASASKWTREGMA 342 + + HIA +T EG A Sbjct: 245 LARVD-IGTAHIAG---YTLEGKA 264
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + +D Sbjct: 201 IISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDT 260 Query: 446 FEDEPYMKPG--------------LAEMKNAVVVPHIA 375 +E+E L E + +V PHIA Sbjct: 261 YENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + +D Sbjct: 201 IISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDT 260 Query: 446 FEDEPYMKPG--------------LAEMKNAVVVPHIA 375 +E+E L E + +V PHIA Sbjct: 261 YENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + +D Sbjct: 201 IISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDT 260 Query: 446 FEDEPYMKPG--------------LAEMKNAVVVPHIA 375 +E+E L E + +V PHIA Sbjct: 261 YENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + +D Sbjct: 201 IISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDT 260 Query: 446 FEDEPYMKPG--------------LAEMKNAVVVPHIA 375 +E+E L E + +V PHIA Sbjct: 261 YENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + +D Sbjct: 201 IISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDT 260 Query: 446 FEDEPYMKPG--------------LAEMKNAVVVPHIA 375 +E+E L E + +V PHIA Sbjct: 261 YENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + +D Sbjct: 201 IISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDT 260 Query: 446 FEDEPYMKPG--------------LAEMKNAVVVPHIA 375 +E+E L E + +V PHIA Sbjct: 261 YENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 47.0 bits (110), Expect = 5e-05 Identities = 43/154 (27%), Positives = 62/154 (40%), Gaps = 15/154 (9%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +I+ H L K TYHL + ++++ V++N SRG VI+ AL+E + + Sbjct: 171 IITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNALLEAINNGIISDA 230 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPN 279 +DV+E EP + L E K + PHIA GY G N Sbjct: 231 VIDVWEHEPEINRELLE-KVLIGTPHIA-----------------------GYSADGKAN 266 Query: 278 AVEPFLDE-----------EATPPPACPSIVNAK 210 A LD E TPP ++ AK Sbjct: 267 ATRMSLDSICRFFHLSATYEITPPAPSSPLIEAK 300
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 47.0 bits (110), Expect = 5e-05 Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 4/99 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +++ H L K T HL + + + +K A+L+NA RG V+D AL+ L V Sbjct: 170 ILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSV 229 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 LDV+E EP + L + K + HIA +T EG A Sbjct: 230 VLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264
>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)| Length = 396 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -2 Query: 596 TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE-DEPYMKP 420 +T ++IN + LA K +VN RG IDE L++ L++ + GLDVF+ +E +K Sbjct: 289 STNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGLDVFKNEETRVKQ 348 Query: 419 GLAEMKNAVVVPHIAS 372 L + +PHI S Sbjct: 349 ELLRRWDVTALPHIGS 364
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI ++ L + T + N ER+A MKK ++VN +RG ++D A+ + + + G DV Sbjct: 248 VIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQAVADACSSGQVAGYGGDV 307 Query: 446 FEDEPYMKP-GLAEMKNAVVVPHIASAS 366 + +P K M N + PHI+ + Sbjct: 308 WFPQPAPKDHPWRYMPNHAMTPHISGTT 335
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 14/115 (12%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI+LH K YH+++ + M+ ++N +RG ++D AL++ L + + LD Sbjct: 200 VITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAALDT 259 Query: 446 FE-----------DEPYMKP---GLAEMKNAVVVPHIASASKWTREGMATLAALN 324 +E D+P P L +N ++ PH A ++ + M +A N Sbjct: 260 YENEVGIFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALDN 314
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 4/91 (4%) Frame = -2 Query: 626 VISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 459 +++LH L T T+H+IN + L + ++L+N SRG V++ L+ L+ V Sbjct: 171 ILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVVNNDDLLAILRCGKKINV 230 Query: 458 GLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP + L + + HIA S Sbjct: 231 ILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 43.9 bits (102), Expect = 4e-04 Identities = 22/64 (34%), Positives = 36/64 (56%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI+LH K YH++N + + MK A ++N +RG +ID L++ L + + LD Sbjct: 201 VITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALDT 260 Query: 446 FEDE 435 +E E Sbjct: 261 YEYE 264
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 43.1 bits (100), Expect = 7e-04 Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+ ++ L + T + N E++A MKK ++VN +RG ++D A+ + + + G DV Sbjct: 249 VVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGDV 308 Query: 446 FEDEPYMKP-GLAEMKNAVVVPHIASAS 366 + +P K M N + PHI+ + Sbjct: 309 WFPQPAPKDHPWRYMPNHAMTPHISGTT 336
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/68 (35%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++SLH HL N + KK A+L+N +RG VI+ L++ L A + G+D Sbjct: 201 LVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDT 260 Query: 446 FEDE-PYM 426 +E E PY+ Sbjct: 261 YEFEGPYI 268
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V+ ++ L + T + N ER+A MKK +VN +RG ++D A+ + + + G DV Sbjct: 250 VVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQAVADACASGHVAGYGGDV 309 Query: 446 FEDEPYMKP-GLAEMKNAVVVPHIASAS 366 + +P K M N + PH + + Sbjct: 310 WFPQPAPKDHPWRYMPNHAMTPHCSGTT 337
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 40.4 bits (93), Expect = 0.004 Identities = 21/64 (32%), Positives = 35/64 (54%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI+LH K YH++N + + MK A ++N +RG +ID L++ L + + L Sbjct: 201 VITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAALVT 260 Query: 446 FEDE 435 +E E Sbjct: 261 YEYE 264
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 40.0 bits (92), Expect = 0.006 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++ ++ L + T + + ER+A +KK ++VN +RG ++D A+V+ + + DV Sbjct: 253 IVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVDACNSGHIAGYSGDV 312 Query: 446 FEDEPYMKP-GLAEMKNAVVVPHIASAS 366 + +P K M N + PHI+ + Sbjct: 313 WYPQPAPKDHPWRYMPNQAMTPHISGTT 340
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++SLH HL N + KK A+L+N +RG +++ L+E L + G+D Sbjct: 201 LVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDT 260 Query: 446 FEDE-PYM 426 +E E PY+ Sbjct: 261 YEFEGPYI 268
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 ++SLH HL N + KK A+L+N +RG +++ L+E L + G+D Sbjct: 201 LVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGIDT 260 Query: 446 FEDE-PYM 426 +E E PY+ Sbjct: 261 YEFEGPYI 268
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 39.7 bits (91), Expect = 0.007 Identities = 22/68 (32%), Positives = 37/68 (54%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V++L+ L T H+IN E L + K+ A +VN +RG + D A+ L++ + DV Sbjct: 250 VVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGDV 309 Query: 446 FEDEPYMK 423 + +P K Sbjct: 310 WFPQPAPK 317
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 38.9 bits (89), Expect = 0.013 Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 6/93 (6%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V++++ L + T L N E ++ MKK + LVN +RG ++ + + E LK+ + G DV Sbjct: 225 VVTINCPLHEKTQGLFNKELISKMKKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGDV 284 Query: 446 FEDEPYMKP-GLAEMKNA-----VVVPHIASAS 366 + +P + L KN +VPH++ S Sbjct: 285 WFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 37.4 bits (85), Expect = 0.037 Identities = 22/88 (25%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI ++ L + T + N E + +KK ++VN +RG +++ A+V+ +++ + DV Sbjct: 256 VIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVESGHIGGYSGDV 315 Query: 446 FEDEPYMKP-GLAEMKNAVVVPHIASAS 366 ++ +P K M N + PH + + Sbjct: 316 WDPQPAPKDHPWRYMPNQAMTPHTSGTT 343
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 35.0 bits (79), Expect = 0.18 Identities = 20/68 (29%), Positives = 37/68 (54%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V++++ L K + L N + ++ MK A LVN +RG + + E +K+ + G DV Sbjct: 238 VVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGGDV 297 Query: 446 FEDEPYMK 423 ++ +P K Sbjct: 298 WDKQPAPK 305
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 35.0 bits (79), Expect = 0.18 Identities = 20/68 (29%), Positives = 37/68 (54%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 V++++ L K + L N + ++ MK A LVN +RG + + E +K+ + G DV Sbjct: 238 VVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGGDV 297 Query: 446 FEDEPYMK 423 ++ +P K Sbjct: 298 WDKQPAPK 305
>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)| Length = 325 Score = 32.3 bits (72), Expect = 1.2 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = -2 Query: 593 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPG 417 T +IN + L + A L+N +RG + E L+ L + + LDVF EP + Sbjct: 217 TVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESP 276 Query: 416 LAEMKNAVVVPHIASASK 363 L + + PH+A+ ++ Sbjct: 277 LWQHPRVTITPHVAAITR 294
>NIP7_YEAST (Q08962) 60S ribosome subunit biogenesis protein NIP7| Length = 181 Score = 31.2 bits (69), Expect = 2.6 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Frame = -2 Query: 431 YMKPGLAEMKNAVVVPHIASAS----KWTREGMATL--AALNVLGKIKGYPVWGNPNAVE 270 Y+ +A++ +V P++ S K+T+ G L +L VL K Y +W PN Sbjct: 46 YVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEM 105 Query: 269 PFL 261 PFL Sbjct: 106 PFL 108
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 29.6 bits (65), Expect = 7.6 Identities = 19/68 (27%), Positives = 34/68 (50%) Frame = -2 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 +++++ L + L+N E L KK A LVN +RG + + +K+ + G DV Sbjct: 223 IVTINCPLHAGSKGLVNAELLKHFKKGAWLVNTARGAICVAEDVAAAVKSGQLRGYGGDV 282 Query: 446 FEDEPYMK 423 + +P K Sbjct: 283 WFPQPAPK 290
>NUOL_BUCAI (P57262) NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH| dehydrogenase I, chain L) (NDH-1, chain L) Length = 614 Score = 29.6 bits (65), Expect = 7.6 Identities = 13/50 (26%), Positives = 24/50 (48%) Frame = +1 Query: 475 LALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLI 624 ++ R S + I L T +F+++ + +G++RWYV G I Sbjct: 555 ISKRLSADPLNKIINYFLKVTQIFNFYLLKTSNGYVRWYVASMILGINFI 604
>FIP1_HUMAN (Q6UN15) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia) Length = 594 Score = 29.3 bits (64), Expect = 10.0 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 473 PMFRVGLDVFEDEPYMKPG 417 P+ V LD FED+P+ KPG Sbjct: 151 PLLEVDLDSFEDKPWRKPG 169
>M4K1_MOUSE (P70218) Mitogen-activated protein kinase kinase kinase kinase 1| (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK) Length = 827 Score = 29.3 bits (64), Expect = 10.0 Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 4/51 (7%) Frame = -2 Query: 329 LNVLGKIKGYPVWGNPNAVEPFLDEEATPPPACP----SIVNAKQLGLPSS 189 L++L K+K P G P +E DEE PPPA P S A LG+P + Sbjct: 285 LDLLDKMKN-PGKGLPVDIE---DEEPEPPPAIPRRIRSTYRASSLGIPDA 331
>KCY_PYRFU (Q8U2L4) Cytidylate kinase (EC 2.7.4.14) (CK) (Cytidine| monophosphate kinase) (CMP kinase) Length = 192 Score = 29.3 bits (64), Expect = 10.0 Identities = 14/35 (40%), Positives = 19/35 (54%) Frame = +1 Query: 208 CLALTMLGQAGGGVASSSRKGSTAFGFPHTGYPLI 312 CL +T+ G AG G + RK + +GF H LI Sbjct: 5 CLVITVSGLAGSGTTTLCRKLAEHYGFKHVYAGLI 39
>FIP1_MOUSE (Q9D824) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 581 Score = 29.3 bits (64), Expect = 10.0 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 473 PMFRVGLDVFEDEPYMKPG 417 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168
>FIP1_RAT (Q5U317) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 536 Score = 29.3 bits (64), Expect = 10.0 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 473 PMFRVGLDVFEDEPYMKPG 417 P+ V LD FED+P+ KPG Sbjct: 150 PLLEVDLDSFEDKPWRKPG 168
>FIP1_PONPY (Q5RAA7) Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1)| Length = 588 Score = 29.3 bits (64), Expect = 10.0 Identities = 11/19 (57%), Positives = 14/19 (73%) Frame = -2 Query: 473 PMFRVGLDVFEDEPYMKPG 417 P+ V LD FED+P+ KPG Sbjct: 136 PLLEVDLDSFEDKPWRKPG 154
>CBID_SYNEL (Q8DKT8) Putative cobalt-precorrin-6A synthase [deacetylating] (EC| 2.1.1.-) Length = 367 Score = 29.3 bits (64), Expect = 10.0 Identities = 14/39 (35%), Positives = 20/39 (51%) Frame = +3 Query: 429 VRLILKNIEADTEHGVSLEVLHQCNLVDHRATARVHQHC 545 V LK +E H + + H + +D RATA +H HC Sbjct: 291 VEAALKFLERMVPHVLPEILSHIAHRIDQRATAYIHAHC 329 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,991,424 Number of Sequences: 219361 Number of extensions: 1750137 Number of successful extensions: 5447 Number of sequences better than 10.0: 125 Number of HSP's better than 10.0 without gapping: 5216 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5429 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5767334219 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
