ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal33p20 |
|---|---|
| Clone Library Name | barley_pub |
>LCFA_SALTY (P63521) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 120 bits (301), Expect = 4e-27 Identities = 65/180 (36%), Positives = 103/180 (57%), Gaps = 1/180 (0%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 518 G++G P+P EAK++ DD E G GELC+K P + YW+RP+ T E I G+ T Sbjct: 378 GSIGLPVPSTEAKLVDDDDNEVAPGEAGELCVKGPQVMLGYWQRPDATDE-IIKDGWLHT 436 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD +DEDG+ I+ R D++ V G+ + EIE V+++H V E A +G+P + GE Sbjct: 437 GDIAVMDEDGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHSGVQEVAAVGVPSGSSGE 495 Query: 337 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 + +V K+ PALT +AL ++ + L YK+P ++ + LP++ +GK+ Sbjct: 496 AVKLFVVKKD-----------PALTDDALITFCRRHLTGYKVPKQVEFREELPKSNVGKI 544
>LCFA_SALTI (P63522) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 120 bits (301), Expect = 4e-27 Identities = 65/180 (36%), Positives = 103/180 (57%), Gaps = 1/180 (0%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 518 G++G P+P EAK++ DD E G GELC+K P + YW+RP+ T E I G+ T Sbjct: 378 GSIGLPVPSTEAKLVDDDDNEVAPGEAGELCVKGPQVMLGYWQRPDATDE-IIKDGWLHT 436 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD +DEDG+ I+ R D++ V G+ + EIE V+++H V E A +G+P + GE Sbjct: 437 GDIAVMDEDGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHSGVQEVAAVGVPSGSSGE 495 Query: 337 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 + +V K+ PALT +AL ++ + L YK+P ++ + LP++ +GK+ Sbjct: 496 AVKLFVVKKD-----------PALTDDALITFCRRHLTGYKVPKQVEFREELPKSNVGKI 544
>LCFA_ECOLI (P69451) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 119 bits (299), Expect = 7e-27 Identities = 66/189 (34%), Positives = 105/189 (55%), Gaps = 1/189 (0%) Frame = -2 Query: 721 NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAES 545 NP G++G P+P EAK++ DD E G GELC+K P + YW+RP+ T E Sbjct: 369 NPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDE- 427 Query: 544 FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 I G+ TGD +DE+G+ I+ R D++ V G+ + EIE V+++H V E A + Sbjct: 428 IIKNGWLHTGDIAVMDEEGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHPGVQEVAAV 486 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G+P + GE + +V K+ P+LT E+L ++ + +L YK+P + D Sbjct: 487 GVPSGSSGEAVKIFVVKKD-----------PSLTEESLVTFCRRQLTGYKVPKLVEFRDE 535 Query: 184 LPRNAMGKV 158 LP++ +GK+ Sbjct: 536 LPKSNVGKI 544
>LCFA_ECOL6 (P69452) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 119 bits (299), Expect = 7e-27 Identities = 66/189 (34%), Positives = 105/189 (55%), Gaps = 1/189 (0%) Frame = -2 Query: 721 NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAES 545 NP G++G P+P EAK++ DD E G GELC+K P + YW+RP+ T E Sbjct: 369 NPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDE- 427 Query: 544 FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 I G+ TGD +DE+G+ I+ R D++ V G+ + EIE V+++H V E A + Sbjct: 428 IIKNGWLHTGDIAVMDEEGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHPGVQEVAAV 486 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G+P + GE + +V K+ P+LT E+L ++ + +L YK+P + D Sbjct: 487 GVPSGSSGEAVKIFVVKKD-----------PSLTEESLVTFCRRQLTGYKVPKLVEFRDE 535 Query: 184 LPRNAMGKV 158 LP++ +GK+ Sbjct: 536 LPKSNVGKI 544
>LCFA_ECO57 (Q8XDR6) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 119 bits (297), Expect = 1e-26 Identities = 65/189 (34%), Positives = 105/189 (55%), Gaps = 1/189 (0%) Frame = -2 Query: 721 NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAES 545 NP G++G P+P EAK++ DD E G GELC++ P + YW+RP+ T E Sbjct: 369 NPYDIDYHSGSIGLPVPSTEAKLVDDDDNEVSPGQPGELCVRGPQVMLGYWQRPDATDE- 427 Query: 544 FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 I G+ TGD +DE+G+ I+ R D++ V G+ + EIE V+++H V E A + Sbjct: 428 IIKNGWLHTGDIAVMDEEGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHPGVQEVAAV 486 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G+P + GE + +V K+ P+LT E+L ++ + +L YK+P + D Sbjct: 487 GVPSGSSGEAVKIFVVKKD-----------PSLTEESLVTFCRRQLTGYKVPKLVEFRDE 535 Query: 184 LPRNAMGKV 158 LP++ +GK+ Sbjct: 536 LPKSNVGKI 544
>LCFA_BACSU (P94547) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 560 Score = 117 bits (292), Expect = 5e-26 Identities = 67/191 (35%), Positives = 101/191 (52%), Gaps = 2/191 (1%) Frame = -2 Query: 724 SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIKSPSLFKEYWKRPEVTA 551 +N + G K G++G P P +A I ++ E GE+ +K P + K YW +PE TA Sbjct: 366 ANFIWGKNKPGSIGCPWPSTDAAIYSEETGELAAPYEHGEIIVKGPQVMKGYWNKPEETA 425 Query: 550 ESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECA 371 DG F TGD +DE+G+F I R DI+ GGY + E+E L EH+ + E Sbjct: 426 AVLRDGWLF-TGDMGYMDEEGFFYIADRKK-DIIIAGGYNIYPREVEEALYEHEAIQEIV 483 Query: 370 VLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLW 191 V G+PD GE + A +V K+ A+ E+ L ++++ +LAPYK+P Sbjct: 484 VAGVPDSYRGETVKAFVVLKKGAKADTEE----------LDAFARSRLAPYKVPKAYEFR 533 Query: 190 DSLPRNAMGKV 158 LP+ A+GK+ Sbjct: 534 KELPKTAVGKI 544
>LCFA_HAEIN (P46450) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 110 bits (274), Expect = 6e-24 Identities = 65/188 (34%), Positives = 100/188 (53%), Gaps = 1/188 (0%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESF 542 P++ + GT+G P+P + KII DDG++ K G GEL +K + + YW+RPE T+E Sbjct: 372 PINVVKHNGTIGVPVPNTDIKIIKDDGSDAKIGEAGELWVKGDQVMRGYWQRPEATSEVL 431 Query: 541 IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 DG + TGD V +DE I+ R DI+ V G+ + EIE V++ + V E +G Sbjct: 432 KDG-WMATGDIVIMDESYSLRIVDRKK-DIILVSGFNVYPNEIEDVVMLNYKVSEAVAIG 489 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 +P GE I +V K+D +LT + L + + L YK+P + D L Sbjct: 490 VPHAVSGETIKIFVVKKDD-----------SLTRDELRNHCRQYLTGYKVPKEIEFRDEL 538 Query: 181 PRNAMGKV 158 P+ +GK+ Sbjct: 539 PKTNVGKI 546
>FAT2_SCHPO (O74976) Putative peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 512 Score = 109 bits (272), Expect = 1e-23 Identities = 69/191 (36%), Positives = 100/191 (52%), Gaps = 2/191 (1%) Frame = -2 Query: 724 SNPLHG-ARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTA 551 +NPL K +VGKP VE KI+ G E G GE+C++ ++ K Y P Sbjct: 317 TNPLPPLVHKPHSVGKPFG-VELKILDQKGNEMPQGKEGEICVRGINVTKGYLNNPAANK 375 Query: 550 ESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECA 371 SF FF+TGD +D+DGY I GR +++ GG K+S EI+AVL++H V E Sbjct: 376 SSFTKDRFFRTGDEGKLDKDGYVFITGRIK-ELVNRGGEKISPAEIDAVLMQHPDVSEAV 434 Query: 370 VLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLW 191 +PDE YG+ I A I P + +T + L + + K+A +KIP + + Sbjct: 435 CFAVPDEKYGQDIQAAINP----------VAGKTVTPKQLHDYLEQKVAAFKIPKKFYFT 484 Query: 190 DSLPRNAMGKV 158 D +P+ A GKV Sbjct: 485 DRIPKTATGKV 495
>LCFA_YERPE (Q8ZES9) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 108 bits (271), Expect = 1e-23 Identities = 66/189 (34%), Positives = 103/189 (54%), Gaps = 1/189 (0%) Frame = -2 Query: 721 NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAES 545 NP G++G P+P + ++ DDG + + G GEL ++ P + YW+RP+ T + Sbjct: 369 NPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVELGKPGELWVRGPQVMLGYWQRPDATDDV 428 Query: 544 FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 DG + TGD T+DEDG+ I+ R D++ V G+ + EIE V+ H VLE AV+ Sbjct: 429 LKDG-WLATGDIATMDEDGFLRIVDRKK-DMILVSGFNVYPNEIEEVVALHAKVLESAVI 486 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G+P+E GE + + V K DA +LT E L + + L YK+P + D Sbjct: 487 GVPNEVSGEAV-KVFVVKNDA----------SLTPEELLTHCRRYLTGYKVPKIVEFRDE 535 Query: 184 LPRNAMGKV 158 LP++ +GK+ Sbjct: 536 LPKSNVGKI 544
>ACSA_BACSU (P39062) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) (Acetyl-CoA synthase) Length = 572 Score = 107 bits (266), Expect = 5e-23 Identities = 64/184 (34%), Positives = 96/184 (52%), Gaps = 3/184 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKD-GVGELCIKS--PSLFKEYWKRPEVTAESFIDGG 530 K G++GKP+P VEA I+ + G E +G L IK PS+ W PE F+ GG Sbjct: 375 KPGSMGKPIPGVEAAIVDNQGNELPPYRMGNLAIKKGWPSMMHTIWNNPEKYESYFMPGG 434 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++ +GD+ +DE+GYF GR + D++ G ++ E+E+ L+EH + E V+G PD Sbjct: 435 WYVSGDSAYMDEEGYFWFQGRVD-DVIMTSGERVGPFEVESKLVEHPAIAEAGVIGKPDP 493 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 GE+I A I RE E + K E + + K LA + P + D LP+ Sbjct: 494 VRGEIIKAFIA----LREGFEPSDK---LKEEIRLFVKQGLAAHAAPREIEFKDKLPKTR 546 Query: 169 MGKV 158 GK+ Sbjct: 547 SGKI 550
>DHBE_BACSU (P40871) 2,3-dihydroxybenzoate-AMP ligase (EC 6.3.2.-)| (Dihydroxybenzoic acid-activating enzyme) Length = 539 Score = 107 bits (266), Expect = 5e-23 Identities = 64/182 (35%), Positives = 101/182 (55%), Gaps = 3/182 (1%) Frame = -2 Query: 691 TVGKPL-PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 518 T GKP+ P E ++ D + K G G L + P + Y+K E A SF + GF++T Sbjct: 352 TQGKPMSPYDEMRVWDDHDRDVKPGETGHLLTRGPYTIRGYYKAEEHNAASFTEDGFYRT 411 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD V + DGY ++ GR I + GG K++A E+E LL H V + A++ +PD+ GE Sbjct: 412 GDIVRLTRDGYIVVEGRAKDQINR-GGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGE 470 Query: 337 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDK-LAPYKIPTRLHLWDSLPRNAMGK 161 C I+P+++A + AE L ++ +++ LA YKIP R+ +S P+ +GK Sbjct: 471 RSCVFIIPRDEAPKAAE-----------LKAFLRERGLAAYKIPDRVEFVESFPQTGVGK 519 Query: 160 VN 155 V+ Sbjct: 520 VS 521
>FAT2_YEAST (P38137) Peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 543 Score = 104 bits (260), Expect = 2e-22 Identities = 61/187 (32%), Positives = 102/187 (54%), Gaps = 3/187 (1%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFID 536 G RK GTVG+P + +I+DD VGE+ I+ ++ Y P+ E+F Sbjct: 351 GKRKPGTVGQP--QGVTVVILDDNDNVLPPGKVGEVSIRGENVTLGYANNPKANKENFTK 408 Query: 535 G-GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 +F+TGD D +G+ ++ GR +++ GG K+S +E++ ++L H + E G+ Sbjct: 409 RENYFRTGDQGYFDPEGFLVLTGRIK-ELINRGGEKISPIELDGIMLSHPKIDEAVAFGV 467 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 PD+ YG+V+ A IV K+ + +T E L ++ K LA +KIPT+++ D LP Sbjct: 468 PDDMYGQVVQAAIVLKKGEK----------MTYEELVNFLKKHLASFKIPTKVYFVDKLP 517 Query: 178 RNAMGKV 158 + A GK+ Sbjct: 518 KTATGKI 524
>ACSA_PASMU (Q9CMW1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 101 bits (251), Expect = 3e-21 Identities = 65/190 (34%), Positives = 101/190 (53%), Gaps = 7/190 (3%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKSP--SLFKEYWKRPEVTAESFID 536 A K G+ PLP + A+++ ++G + + G L IK P S+ + W PE ++ Sbjct: 434 ATKPGSCTLPLPGIMAEVLDENGQKCAVEQGGALAIKRPFPSMLRTIWNDPERYKSTYFP 493 Query: 535 ----GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAV 368 G ++ GD D+DGYF ILGRT+ D++ V G++L +EIE+ L+ V E AV Sbjct: 494 AEYGGKYYIAGDNAHRDKDGYFWILGRTD-DVLNVSGHRLGTMEIESALVASPKVAEAAV 552 Query: 367 LGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWD 188 +G PDE GE I A +V D R E+A + A E L +W +++ P + D Sbjct: 553 VGKPDEIKGEAIVAFVV-LNDFRPEGEEARQLA---EELKAWVSNEIGKIARPEDIRFAD 608 Query: 187 SLPRNAMGKV 158 +LP+ GK+ Sbjct: 609 NLPKTRSGKI 618
>MENE_BACSU (P23971) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 486 Score = 100 bits (249), Expect = 5e-21 Identities = 66/188 (35%), Positives = 94/188 (50%) Frame = -2 Query: 721 NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESF 542 +P K G+ GKPL E KI D GE+ +K P++ K Y+ R SF Sbjct: 299 SPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASF 358 Query: 541 IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 G+ KTGD +D +G+ +L R +D++ GG + E+E+VLL H V E V G Sbjct: 359 -QNGWLKTGDLGYLDNEGFLYVLDR-RSDLIISGGENIYPAEVESVLLSHPAVAEAGVSG 416 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 D+ +G+V A +V KP E LT + K++LA YKIP + + D L Sbjct: 417 AEDKKWGKVPHAYLV-----------LHKPVSAGE-LTDYCKERLAKYKIPAKFFVLDRL 464 Query: 181 PRNAMGKV 158 PRNA K+ Sbjct: 465 PRNASNKL 472
>ENTE_ECOLI (P10378) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 98.2 bits (243), Expect = 2e-20 Identities = 61/181 (33%), Positives = 94/181 (51%), Gaps = 2/181 (1%) Frame = -2 Query: 691 TVGKPL-PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 518 T G P+ P E + +G G VG L + P F+ Y+K P+ A +F GF+ + Sbjct: 354 TQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCS 413 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD +++D +GY + GR I + GG K++A EIE +LL H V+ A++ + DE GE Sbjct: 414 GDLISIDPEGYITVQGREKDQINR-GGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGE 472 Query: 337 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 CA +V KE P ++ + +A +K+P R+ DSLP A+GKV Sbjct: 473 KSCAYLVVKE-----------PLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKV 521 Query: 157 N 155 + Sbjct: 522 D 522
>ENTE_ECO57 (Q8XBV3) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 98.2 bits (243), Expect = 2e-20 Identities = 61/181 (33%), Positives = 94/181 (51%), Gaps = 2/181 (1%) Frame = -2 Query: 691 TVGKPL-PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 518 T G P+ P E + +G G VG L + P F+ Y+K P+ A +F GF+ + Sbjct: 354 TQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCS 413 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD +++D +GY + GR I + GG K++A EIE +LL H V+ A++ + DE GE Sbjct: 414 GDLISIDPEGYITVQGREKDQINR-GGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGE 472 Query: 337 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 CA +V KE P ++ + +A +K+P R+ DSLP A+GKV Sbjct: 473 KSCAYLVVKE-----------PLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKV 521 Query: 157 N 155 + Sbjct: 522 D 522
>ACSA_NITEU (Q82SI5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 655 Score = 97.8 bits (242), Expect = 3e-20 Identities = 58/189 (30%), Positives = 95/189 (50%), Gaps = 8/189 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGE-LCIKSP--SLFKEYWKRPEVTAESFID-- 536 K G+ PLP ++A ++ + G + G G L IK P S+ + W PE +++ Sbjct: 438 KPGSCTLPLPGIDAAVVDETGHPVEQGKGGFLVIKRPFPSMLRTLWNDPERFRKTYFPTD 497 Query: 535 ---GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 G ++ GD+ D+DGYF I+GR + D++ V G++L +EIE+ L+ H V E AV+ Sbjct: 498 IAGGRYYLAGDSAHRDQDGYFWIMGRVD-DVLNVSGHRLGTMEIESALVAHPLVAEAAVV 556 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G P E GEV+ A + RE+ + A L W ++ P + ++ Sbjct: 557 GKPHEIKGEVVVAFVT----LREKLPDDQRAAEIAATLREWVASEIGAIARPEEIRFGEN 612 Query: 184 LPRNAMGKV 158 LP+ GK+ Sbjct: 613 LPKTRSGKI 621
>ACSA_RALEU (P31638) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 660 Score = 97.8 bits (242), Expect = 3e-20 Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 10/197 (5%) Frame = -2 Query: 718 PLHGARK--EGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVT 554 PL GA G+ PLP + A I+ + G + +G G + + P++ + W PE Sbjct: 435 PLPGATPLVPGSCTLPLPGIMAAIVDETGHDVPNGNGGILVVKRPWPAMIRTIWGDPERF 494 Query: 553 AESF----IDGGFFKTGDTVTVDED-GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 +S+ + G + GD D+D GYF I+GR + D++ V G+++ +EIE+ L+ + Sbjct: 495 RKSYFPEELGGKLYLAGDGSIRDKDTGYFTIMGRID-DVLNVSGHRMGTMEIESALVSNP 553 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIP 209 V E AV+G PD+ GE ICA +V K +R E+A K A L +W ++ P P Sbjct: 554 LVAEAAVVGRPDDMTGEAICAFVVLKR-SRPTGEEAVKIATELR---NWVGKEIGPIAKP 609 Query: 208 TRLHLWDSLPRNAMGKV 158 + D+LP+ GK+ Sbjct: 610 KDIRFGDNLPKTRSGKI 626
>ACSA_RALSO (Q8XY11) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 660 Score = 97.4 bits (241), Expect = 4e-20 Identities = 63/198 (31%), Positives = 103/198 (52%), Gaps = 10/198 (5%) Frame = -2 Query: 721 NPLHGARK--EGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEV 557 +PL GA G+ PLP + A I+ + G + DG G + + P++ + W PE Sbjct: 434 SPLPGATPLVPGSCTLPLPGIMAAIVDETGQDLPDGQGGILVVKRPWPAMIRTIWGDPER 493 Query: 556 TAESF----IDGGFFKTGD-TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEH 392 +S+ + G + GD +V E GYF I+GR + D++ V G+++ +EIE+ L+ + Sbjct: 494 FRKSYFPAELGGKLYLAGDGSVRDKETGYFTIMGRID-DVLNVSGHRMGTMEIESALVAN 552 Query: 391 DTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKI 212 V E AV+G PD+ GE ICA +V K R ++A + A L +W ++ P Sbjct: 553 PLVAEAAVVGRPDDMTGEAICAFVVLKR-TRPNGDEARQIATDLR---NWVGKEIGPIAK 608 Query: 211 PTRLHLWDSLPRNAMGKV 158 P + D+LP+ GK+ Sbjct: 609 PKDIRFGDNLPKTRSGKI 626
>MENE_BACCZ (Q632I5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 96.7 bits (239), Expect = 7e-20 Identities = 58/181 (32%), Positives = 95/181 (52%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 K G+ GKPL + + +I D GE+ +K P++ Y+ R + T E+ I G+ Sbjct: 304 KVGSAGKPLFQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLH 362 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +DE+G+ +L R +D++ GG + +IE VLL H V E V+G+ D+ +G Sbjct: 363 TGDLGYLDEEGFLYVLDR-RSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWG 421 Query: 340 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 161 +V A +V + +T E + + ++KLA YK+P + + LPRNA K Sbjct: 422 QVPAAFVVKSGE------------ITEEEILHFCEEKLAKYKVPKKAWFLEELPRNASKK 469 Query: 160 V 158 + Sbjct: 470 L 470
>MENE_BACAN (Q81K97) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 96.3 bits (238), Expect = 9e-20 Identities = 58/181 (32%), Positives = 95/181 (52%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 K G+ GKPL + + +I D GE+ +K P++ Y+ R + T E+ I G+ Sbjct: 303 KVGSAGKPLFQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLH 361 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +DE+G+ +L R +D++ GG + +IE VLL H V E V+G+ D+ +G Sbjct: 362 TGDLGYLDEEGFLYVLDR-RSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWG 420 Query: 340 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 161 +V A +V + +T E + + ++KLA YK+P + + LPRNA K Sbjct: 421 QVPAAFVVKSGE------------ITEEEILHFCEEKLAKYKVPKKACFLEELPRNASKK 468 Query: 160 V 158 + Sbjct: 469 L 469
>MENE_BACHK (Q6HC29) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 96.3 bits (238), Expect = 9e-20 Identities = 58/181 (32%), Positives = 94/181 (51%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 K G+ GKPL + + +I D GE+ +K P++ Y+ R + T E+ I G+ Sbjct: 304 KVGSAGKPLFQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLH 362 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +DE+G+ +L R +D++ GG + +IE VLL H V E V+G+ D+ +G Sbjct: 363 TGDLGYLDEEGFLYVLDR-RSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWG 421 Query: 340 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 161 +V A +V + E E + + ++KLA YK+P + + LPRNA K Sbjct: 422 QVPAAFVVKSGEVTE------------EEILHFCEEKLAKYKVPKKACFLEELPRNASKK 469 Query: 160 V 158 + Sbjct: 470 L 470
>MENE_BACCR (Q816I1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 95.9 bits (237), Expect = 1e-19 Identities = 59/181 (32%), Positives = 95/181 (52%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 K G+ GKPL + + +I D GE+ +K P++ Y+ R + T E+ I G+ Sbjct: 304 KVGSAGKPLFQCQLRIEKDGVVVPPLVEGEIVVKGPNVTGGYFNREDATRET-IQNGWLH 362 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +DE+G+ +L R +D++ GG + +IE VLL H V E V+G+ D+ +G Sbjct: 363 TGDLGYLDEEGFLYVLDR-RSDLIISGGENIYPAQIEEVLLSHPAVAEAGVVGMSDDKWG 421 Query: 340 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 161 +V A +V A+T E + + ++KLA YK+P + + LPRNA K Sbjct: 422 QVPAAFVV------------KSGAVTEEEILHFCEEKLAKYKVPKKACFLEELPRNASKK 469 Query: 160 V 158 + Sbjct: 470 L 470
>CAIC_PROSL (Q8GB18) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 518 Score = 95.5 bits (236), Expect = 1e-19 Identities = 57/186 (30%), Positives = 100/186 (53%), Gaps = 4/186 (2%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPS---LFKEYWKRPEVTAESFID 536 R+ ++G+P +A+I + +GV GE+C+K + LFKEY+ RP+ T ++ Sbjct: 338 RRWPSIGRPGFCYQAQIRDKQNQQVPNGVVGEICVKGEAGKTLFKEYYNRPDATEKALEP 397 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD D++G+F + R+ +++K GG +S +EIE ++ H + + AV+G+P Sbjct: 398 DGWLHTGDYGYRDDEGFFYFVDRS-CNMIKRGGENVSCIEIENIIASHPKIQDVAVIGVP 456 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D+ E I A +V L+ EA ++ + +A +K+P+ + LPR Sbjct: 457 DDIRDEAIKAFVV----------LVDGETLSEEAFFAFCEQNMAKFKVPSAVEFKQGLPR 506 Query: 175 NAMGKV 158 N GKV Sbjct: 507 NCSGKV 512
>MENE_BACC1 (Q72YK9) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 94.0 bits (232), Expect = 4e-19 Identities = 58/181 (32%), Positives = 93/181 (51%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 K G+ GKPL + + +I D GE+ +K P++ Y+ R + T E+ I G+ Sbjct: 303 KVGSAGKPLFQCQLRIEKDGVVVPAFTEGEIVVKGPNVTGGYFNREDATRET-IQNGWLH 361 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +DE+G+ +L R +D++ GG + +IE VLL H V E V+G+ D+ +G Sbjct: 362 TGDIGYLDEEGFLYVLDR-RSDLIISGGENIYPAQIEEVLLSHPAVAEAGVVGMTDDKWG 420 Query: 340 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 161 +V A +V + E E + + + KLA YK+P + + LPRNA K Sbjct: 421 QVPVAFVVKSGEVTE------------EEIIHFCEAKLAKYKVPKKACFLEELPRNASKK 468 Query: 160 V 158 + Sbjct: 469 L 469
>MENE_LISMF (Q71YZ5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 94.0 bits (232), Expect = 4e-19 Identities = 65/187 (34%), Positives = 94/187 (50%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFI 539 P K G+ GK L E KI D GE+ +K PS+ Y + T SF+ Sbjct: 293 PKDALNKIGSSGKALFPAEVKIADD---------GEILLKGPSITPGYLHNKKATEASFV 343 Query: 538 DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 DG +FKTGD +DE+G+ +L R +D++ GG + EIE V+ E++ V E AV+G Sbjct: 344 DG-WFKTGDIGYLDEEGFLFVLER-RSDLIISGGENIYPTEIEHVISEYEGVKEVAVIGK 401 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 PD+ +G V A IV +E E L + LA YKIP ++ + + LP Sbjct: 402 PDDKWGSVPVAFIVAEETFDE------------AELRLICETNLAGYKIPKQITIVEKLP 449 Query: 178 RNAMGKV 158 + A GK+ Sbjct: 450 KTASGKI 456
>ACSA_HELPY (O25686) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 662 Score = 92.8 bits (229), Expect = 1e-18 Identities = 62/199 (31%), Positives = 110/199 (55%), Gaps = 11/199 (5%) Frame = -2 Query: 721 NPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRPEV 557 +PL GA + PLP + A+++ +DGT+TK G G LCI P S+ + W + Sbjct: 430 SPLPGATPIRASCATLPLPGIHAEVLNEDGTKTKPGEQGFLCITKPWPSMIRNIWGDEKR 489 Query: 556 TAESF-----IDGGF-FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLE 395 +S+ ++G + + +GD VDE+GY I+GRT+ DI+ V G+++ E+E+ + + Sbjct: 490 YIDSYFSQIKLNGEYVYLSGDGAIVDENGYITIIGRTD-DIVNVSGHRIGTAEVESAISK 548 Query: 394 HDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYK 215 H+ V ECAV+G+PD GE + A +V + A+ ++ + + + S K+A K Sbjct: 549 HEMVAECAVVGIPDAIKGEGLFAFVVLCDGAKCNLGESLELLKEMNHILSIEIGKIA--K 606 Query: 214 IPTRLHLWDSLPRNAMGKV 158 + +++ LP+ GK+ Sbjct: 607 LDNVMYV-PGLPKTRSGKI 624
>FADK_ECOLI (P38135) Short-chain-fatty-acid--CoA ligase (EC 6.2.1.-) (Acyl-CoA| synthetase) Length = 548 Score = 92.8 bits (229), Expect = 1e-18 Identities = 59/180 (32%), Positives = 95/180 (52%), Gaps = 2/180 (1%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 515 T G VE K++ D G GE + P++F Y+ PE+TA + + G++ +G Sbjct: 357 TDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNVFMGYFDEPELTARALDEEGWYYSG 416 Query: 514 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 335 D +DE GY I GR DI+ GG +S+ E+E +LL+H + + V+ + DE GE Sbjct: 417 DLCRMDEAGYIKITGR-KKDIIVRGGENISSREVEDILLQHPKIHDACVVAMSDERLGER 475 Query: 334 ICAIIVPKEDARERAEQASKPALTLEALTS-WSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 CA +V K A +L+LE + + +S+ ++A YK P + + + LPR GK+ Sbjct: 476 SCAYVVLK---------APHHSLSLEEVVAFFSRKRVAKYKYPEHIVVIEKLPRTTSGKI 526
>ACS1_KLULA (O60011) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 707 Score = 92.4 bits (228), Expect = 1e-18 Identities = 55/157 (35%), Positives = 85/157 (54%), Gaps = 4/157 (2%) Frame = -2 Query: 616 GELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIM 449 G L IK P S + WK + ++++ G++ TGD V D+DG+F ILGR + D++ Sbjct: 515 GVLAIKRPWPSFARTIWKNNDRFLDTYLKPYPGYYFTGDGVARDKDGFFWILGRVD-DVV 573 Query: 448 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 269 V G++LS EIEA ++E D V ECAV+G DE G+ + A +V K + A S+ Sbjct: 574 NVSGHRLSTAEIEAAIIEDDMVAECAVVGFNDELTGQAVAAFVVLKNKSSLTAASESELQ 633 Query: 268 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 + L + + P+ P + L D LP+ GK+ Sbjct: 634 DIKKHLIITVRKDIGPFAAPKLIVLVDDLPKTRSGKI 670
>MENE_LISMO (P58730) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 92.0 bits (227), Expect = 2e-18 Identities = 64/187 (34%), Positives = 94/187 (50%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFI 539 P K G+ GK L E KI D GE+ +K PS+ Y + T SF+ Sbjct: 293 PKDALNKIGSSGKALFPAEVKIADD---------GEILLKGPSITPGYLHNKKATEASFV 343 Query: 538 DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 DG +FKTGD +DE+G+ ++ R +D++ GG + EIE V+ E+ V E AV+G Sbjct: 344 DG-WFKTGDIGYLDEEGFLFVVER-RSDLIISGGENIYPTEIEHVIGEYVAVKEVAVIGQ 401 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 PD+ +G V A IV +E E + L + LA YKIP ++ + + LP Sbjct: 402 PDDKWGSVPVAFIVAEETFDE------------DELQLICQTNLASYKIPKQIIIVEKLP 449 Query: 178 RNAMGKV 158 + A GK+ Sbjct: 450 KTASGKI 456
>CAIC_SALTY (Q8ZRX4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 90.9 bits (224), Expect = 4e-18 Identities = 58/186 (31%), Positives = 97/186 (52%), Gaps = 4/186 (2%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFID 536 R+ ++G+ EA+I D G +GE+CIK ++FKEY+ +PE TA++ Sbjct: 337 RRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAKALEP 396 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD+ DEDGYF + R +++K GG +S +E+E ++ H + + V+G+ Sbjct: 397 EGWLHTGDSGYQDEDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIK 455 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D E I A IV E L+ S+ ++ +A +K+P+ + + LPR Sbjct: 456 DAIRDEAIKAFIVLNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPR 505 Query: 175 NAMGKV 158 N GK+ Sbjct: 506 NCSGKI 511
>CAIC_SALTI (Q8Z9L4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 90.5 bits (223), Expect = 5e-18 Identities = 58/186 (31%), Positives = 96/186 (51%), Gaps = 4/186 (2%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFID 536 R+ ++G+ EA+I D G +GE+CIK ++FKEY+ +PE TA + Sbjct: 337 RRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEP 396 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD+ DEDGYF + R +++K GG +S +E+E ++ H + + V+G+ Sbjct: 397 EGWLHTGDSGYQDEDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIK 455 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D E I A IV E L+ S+ ++ +A +K+P+ + + LPR Sbjct: 456 DAIRDEAIKAFIVLNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPR 505 Query: 175 NAMGKV 158 N GK+ Sbjct: 506 NCSGKI 511
>CAIC_SALPA (Q5PIL0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 90.5 bits (223), Expect = 5e-18 Identities = 58/186 (31%), Positives = 96/186 (51%), Gaps = 4/186 (2%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFID 536 R+ ++G+ EA+I D G +GE+CIK ++FKEY+ +PE TA + Sbjct: 337 RRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEP 396 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD+ DEDGYF + R +++K GG +S +E+E ++ H + + V+G+ Sbjct: 397 EGWLHTGDSGYQDEDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIK 455 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D E I A IV E L+ S+ ++ +A +K+P+ + + LPR Sbjct: 456 DAIRDEAIKAFIVLNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPR 505 Query: 175 NAMGKV 158 N GK+ Sbjct: 506 NCSGKI 511
>MENE_OCEIH (Q8ENZ7) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 480 Score = 90.5 bits (223), Expect = 5e-18 Identities = 61/187 (32%), Positives = 96/187 (51%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFI 539 P +K G+ GKPL + KI ++ + +GE+ +K P + K Y+KR E E F Sbjct: 303 PEDALKKIGSAGKPLFPAQLKIAHNENNPNQ--IGEILVKGPMVTKGYYKRAETNKEVF- 359 Query: 538 DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 + + TGD +DE GY ++ R N D++ GG + EIE VL++ + + E V G Sbjct: 360 ENNWLHTGDMGYLDEQGYLYVVDRRN-DLIISGGENIYPSEIENVLVQIEGIEEAGVKGS 418 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 P+E +G V A IV S+P ++ + + + LA YK P +H+ + LP Sbjct: 419 PNEEWGMVPIAFIV-----------CSRP-ISENEIAAHLEKYLAKYKRPKEIHVVNELP 466 Query: 178 RNAMGKV 158 RNA K+ Sbjct: 467 RNAANKL 473
>CAIC_SALCH (Q57TJ0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 89.7 bits (221), Expect = 8e-18 Identities = 58/186 (31%), Positives = 96/186 (51%), Gaps = 4/186 (2%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFID 536 R+ ++G+ EA+I D G +GE+CIK ++FKEY+ +PE TA + Sbjct: 337 RRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAGALEP 396 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD+ DEDGYF + R +++K GG +S +E+E ++ H + + V+G+ Sbjct: 397 EGWLHTGDSGYQDEDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIK 455 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D E I A IV E L+ S+ ++ +A +K+P+ + + LPR Sbjct: 456 DAIRDEAIKAFIVLNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPR 505 Query: 175 NAMGKV 158 N GK+ Sbjct: 506 NCSGKI 511
>ACSA_PYRAE (O93730) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 89.7 bits (221), Expect = 8e-18 Identities = 59/186 (31%), Positives = 89/186 (47%), Gaps = 5/186 (2%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRPEVTAESFIDG- 533 K GT G PLP E ++ ++G GV G L IK P + W PE +++ Sbjct: 450 KPGTNGPPLPGFEVDVVDENGNPAPPGVKGYLVIKKPWPGMLHGIWGDPERYIKTYWSRF 509 Query: 532 -GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G F GD D+DGY +LGR + +++KV G++L E+E+ L+ H V E AV+G+P Sbjct: 510 PGMFYAGDYAIKDKDGYIWVLGRAD-EVIKVAGHRLGTYELESALISHPAVAESAVVGVP 568 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D GEV A +V K+ E + L + + P P ++ LP+ Sbjct: 569 DAIKGEVPIAFVVLKQGVAPSDELRKE-------LREHVRRTIGPIAEPAQIFFVTKLPK 621 Query: 175 NAMGKV 158 GK+ Sbjct: 622 TRSGKI 627
>ACS1_YEAST (Q01574) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 713 Score = 88.6 bits (218), Expect = 2e-17 Identities = 56/189 (29%), Positives = 95/189 (50%), Gaps = 8/189 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGT----ETKDGVGELCIKS--PSLFKEYWKRPEVTAESFI 539 K G+ P ++A +++D T T G L +K+ PS + WK + ++++ Sbjct: 490 KPGSASFPFFGIDA-VVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYL 548 Query: 538 DG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 + G++ TGD D+DGY ILGR + D++ V G++LS EIEA ++E V ECAV+ Sbjct: 549 NPYPGYYFTGDGAAKDKDGYIWILGRVD-DVVNVSGHRLSTAEIEAAIIEDPIVAECAVV 607 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G D+ G+ + A +V K + + + L + + P+ P + L D Sbjct: 608 GFNDDLTGQAVAAFVVLKNKSSWSTATDDELQDIKKHLVFTVRKDIGPFAAPKLIILVDD 667 Query: 184 LPRNAMGKV 158 LP+ GK+ Sbjct: 668 LPKTRSGKI 676
>ACSA_METSO (P27095) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 88.6 bits (218), Expect = 2e-17 Identities = 57/192 (29%), Positives = 94/192 (48%), Gaps = 11/192 (5%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF---- 542 K G+ PLP + I+ ++G E G G + PS+ + +W E + + Sbjct: 456 KPGSCTFPLPGYDISILDEEGNEVPLGSGGNIVALKPYPSMLRAFWGDKERFMKEYWQFY 515 Query: 541 --IDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 + G G + GD D+DGYF I GR + D++ V G++++ E+E+ L+ H + E Sbjct: 516 WDVPGRRGVYLAGDKAQRDKDGYFFIQGRID-DVLSVAGHRIANAEVESALVAHPKIAEA 574 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHL 194 AV+G PDE GE I A ++ R P L +A+ ++ + L P PT +H Sbjct: 575 AVVGKPDEVKGESIVAFVI------LRVGNEPSPELAKDAI-AFVRKTLGPVAAPTEVHF 627 Query: 193 WDSLPRNAMGKV 158 + LP+ GK+ Sbjct: 628 VNDLPKTRSGKI 639
>LUCI_LUCMI (Q26304) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 88.2 bits (217), Expect = 2e-17 Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 4/189 (2%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFI 539 G K G GK +P + K+I D T+ GV GE+C+K PSL Y PE T E+ Sbjct: 357 GDDKPGASGKVVPLFKVKVI-DLDTKKTLGVNRRGEICVKGPSLMLGYSNNPEATRETID 415 Query: 538 DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 + G+ TGD DED +F I+ R + ++K GY++ E+E+VLL+H + + V G+ Sbjct: 416 EEGWLHTGDIGYYDEDEHFFIVDRLKS-LIKYKGYQVPPAELESVLLQHPNIFDAGVAGV 474 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYK-IPTRLHLWDSL 182 PD GE+ A++V ++ +T + + + ++ +K + + D + Sbjct: 475 PDPDAGELPGAVVVMEKG----------KTMTEKEIVDYVNSQVVNHKRLRGGVRFVDEV 524 Query: 181 PRNAMGKVN 155 P+ GK++ Sbjct: 525 PKGLTGKID 533
>TYCA_BREPA (P09095) Tyrocidine synthetase 1 (Tyrocidine synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1088 Score = 88.2 bits (217), Expect = 2e-17 Identities = 55/185 (29%), Positives = 89/185 (48%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP+ I+ +D G GELCI L + YW RP++TAE F+D F Sbjct: 337 IGKPIQNTHIYIVNEDLQLLPTGSEGELCIGGVGLARGYWNRPDLTAEKFVDNPFVPGEK 396 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + K+ G+++ EIE+VLL H+ + E V+ D+ Sbjct: 397 MYRTGDLAKWLTDGTIEFLGRIDHQV-KIRGHRIELGEIESVLLAHEHITEAVVIAREDQ 455 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 G+ +CA + +++A T L ++ KL Y +P+ D +P Sbjct: 456 HAGQYLCAYYISQQEA------------TPAQLRDYAAQKLPAYMLPSYFVKLDKMPLTP 503 Query: 169 MGKVN 155 K++ Sbjct: 504 NDKID 508
>VIBE_VIBCH (O07899) Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase (EC| 6.3.2.-) (Dihydroxybenzoic acid-activating enzyme) Length = 543 Score = 87.8 bits (216), Expect = 3e-17 Identities = 55/181 (30%), Positives = 93/181 (51%), Gaps = 2/181 (1%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDD-GTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 518 T G+P+ + +++D+ G G G L + P + Y++ + +F GF+ T Sbjct: 356 TQGRPISAHDQLLVVDEQGQPVASGEEGYLLTQGPYTIRGYYRADQHNQRAFNAQGFYIT 415 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD V + +GY I+ GR I + GG K++A E+E LL H V + A++ + DE GE Sbjct: 416 GDKVKLSSEGYVIVTGRAKDQINR-GGEKIAAEEVENQLLHHPAVHDAALIAISDEYLGE 474 Query: 337 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 CA+IV K + + T++ + LA YKIP ++ D LP+ ++GK+ Sbjct: 475 RSCAVIVLKPE---------QSVNTIQLKRFLHQAGLADYKIPDQIQFIDQLPKTSVGKI 525 Query: 157 N 155 + Sbjct: 526 D 526
>GRSA_BREBE (P0C062) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 87.8 bits (216), Expect = 3e-17 Identities = 58/186 (31%), Positives = 92/186 (49%), Gaps = 8/186 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKD--GVGELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 +G P+ + I+ D+ + K GELCI L + YWKRPE+T++ F+D F Sbjct: 348 IGAPIQNTQIYIV-DENLQLKSVGEAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGE 406 Query: 526 --FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 +KTGD DG LGR + + K+ G+++ E+E++LL+H + E AV D Sbjct: 407 KLYKTGDQARWLPDGNIEYLGRIDNQV-KIRGHRVELEEVESILLKHMYISETAVSVHKD 465 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 +CAI V S+ + LE L +S ++L Y IP+ D +P Sbjct: 466 HQEQPYLCAIFV------------SEKHIPLEQLRQFSSEELPTYMIPSYFIQLDKMPLT 513 Query: 172 AMGKVN 155 + GK++ Sbjct: 514 SNGKID 519
>ACS1_CANGA (Q6FLU2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 704 Score = 87.8 bits (216), Expect = 3e-17 Identities = 64/194 (32%), Positives = 97/194 (50%), Gaps = 13/194 (6%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDD--GTETKDGVGE--LCIKSP--SLFKEYWKRPEVTAESFI 539 K G+ P +E +I+D G E D E L IK P S + WK + ++++ Sbjct: 481 KPGSASLPFFGIET-VILDPTTGEEINDSHAEGVLAIKRPWPSFARTIWKNHDRFLDTYL 539 Query: 538 DG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 + G++ TGD D+DGY ILGR + D++ V G++LS EIEA ++E V ECAV+ Sbjct: 540 NPYKGYYFTGDGAARDKDGYIWILGRVD-DVVNVSGHRLSTAEIEAAIIEDRMVAECAVV 598 Query: 364 GLPDEAYGEVICAIIVPKE-----DARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL 200 G D+ G+ + A +V K+ A E Q K L L + + P+ P + Sbjct: 599 GFNDDLTGQAVAAFVVLKDKSTWASASEEELQDIKKHLILTV-----RKDIGPFAAPKLI 653 Query: 199 HLWDSLPRNAMGKV 158 L D LP+ GK+ Sbjct: 654 VLVDDLPKTRSGKI 667
>LUCI_PHOPY (P08659) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 550 Score = 87.4 bits (215), Expect = 4e-17 Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 3/134 (2%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFI 539 G K G VGK +P EAK++ D +T GV GELC++ P + Y PE T Sbjct: 355 GDDKPGAVGKVVPFFEAKVVDLDTGKTL-GVNQRGELCVRGPMIMSGYVNNPEATNALID 413 Query: 538 DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 G+ +GD DED +F I+ R + ++K GY+++ E+E++LL+H + + V GL Sbjct: 414 KDGWLHSGDIAYWDEDEHFFIVDRLKS-LIKYKGYQVAPAELESILLQHPNIFDAGVAGL 472 Query: 358 PDEAYGEVICAIIV 317 PD+ GE+ A++V Sbjct: 473 PDDDAGELPAAVVV 486
>BACC_BACLI (O68008) Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine Length = 6359 Score = 87.4 bits (215), Expect = 4e-17 Identities = 59/185 (31%), Positives = 88/185 (47%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G P+ ++ + GV GELC+ SL + Y RPE+TAE FI F Sbjct: 1803 IGSPIANTNVYVLDQNQKPVPTGVVGELCVGGMSLARGYLNRPELTAEKFISHPFASGER 1862 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG+ LGR + + K+ GY++ EIE LL+ D + E AV+ D+ Sbjct: 1863 LYRTGDLARWLPDGHLEFLGRIDHQV-KIRGYRIELGEIENQLLKLDKIDEAAVIARKDD 1921 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + + +CA IV KED T ++ W + +L Y IP D LP + Sbjct: 1922 DHSDYLCAYIVSKED------------WTSTEISEWLEKELPHYMIPAYFVRLDKLPLTS 1969 Query: 169 MGKVN 155 KV+ Sbjct: 1970 NDKVD 1974 Score = 81.3 bits (199), Expect = 3e-15 Identities = 55/185 (29%), Positives = 89/185 (48%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP V+ I+ + G+ GEL I + K Y +PE+T+E F+ F Sbjct: 5857 IGKPASNVQLYILDERQEVQPVGIAGELYISGDGVAKGYLNKPELTSEKFLPNPFLPGER 5916 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD + DG+ LGR + + K+ GY++ EIE LL H + E AV D+ Sbjct: 5917 MYRTGDLAKMRPDGHIEYLGRIDHQV-KIRGYRIELGEIEHQLLRHSDIKEAAVAAKTDQ 5975 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 +V+CA +V + D +T + + ++ +L Y +P+ L D LP Sbjct: 5976 NNDQVLCAYVVSERD------------ITQKDIKTFLAKELPEYMVPSYLLKLDELPLTP 6023 Query: 169 MGKVN 155 GKV+ Sbjct: 6024 NGKVD 6028 Score = 74.7 bits (182), Expect = 3e-13 Identities = 59/185 (31%), Positives = 81/185 (43%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G PL I+ + G GV GELCI L K Y R E+TAE FI F Sbjct: 771 IGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGER 830 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +KTGD DG +GR + + K+ G+++ EIE+ L H+ + E V DE Sbjct: 831 LYKTGDLAKWLPDGNIEFIGRIDHQV-KIRGFRIELGEIESRLEMHEDINETIVTVREDE 889 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 ICA I + ++L+ L + +KL Y IP D LP Sbjct: 890 ESRPYICAYITANRE------------ISLDELKGFLGEKLPEYMIPAYFVKMDKLPLTK 937 Query: 169 MGKVN 155 GKV+ Sbjct: 938 NGKVD 942 Score = 69.3 bits (168), Expect = 1e-11 Identities = 53/185 (28%), Positives = 88/185 (47%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G+P+ + I+ + G GELC+ L + Y RP++T E F+ F Sbjct: 3308 IGRPISNHKVYILNHNQQLLPLGTPGELCLSGEGLARGYLNRPDLTLEKFVPNPFAPGES 3367 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + K+ G+++ EIE LL+ + + AV+ D+ Sbjct: 3368 MYRTGDLARFLPDGQIEYLGRIDHQV-KIRGFRIELGEIENQLLKIEGIDAAAVMAREDQ 3426 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 A G+ +CA IV A++A+ A + L +L Y +P+ D LP A Sbjct: 3427 AGGKYLCAYIV--------ADKAAGVADVRKCLLK----ELPDYMVPSYFVKLDQLPLTA 3474 Query: 169 MGKVN 155 GK++ Sbjct: 3475 NGKID 3479 Score = 68.2 bits (165), Expect = 3e-11 Identities = 49/185 (26%), Positives = 82/185 (44%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G P+ A ++ ++ +GV GELCI + Y RP+ T E FI+ F Sbjct: 4351 IGTPIHNTNAYVLDENMKLLPEGVYGELCIAGAGVTGGYVNRPDETKEKFIENPFAPHTK 4410 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG + GR + + KV GY++ EI+ LL HD + E + D Sbjct: 4411 MYRTGDLARRLSDGNIELAGRIDTQV-KVRGYRIEPEEIKNRLLAHDDIKEAFIAAREDH 4469 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + +CA + L E + ++ +L Y IP+ + +P +A Sbjct: 4470 KGAKQLCAYFTADAE------------LPFEDIRTYLMHELPEYMIPSSFVQIEKMPLSA 4517 Query: 169 MGKVN 155 GK++ Sbjct: 4518 NGKID 4522
>ACSA_MYCTU (O69635) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 87.4 bits (215), Expect = 4e-17 Identities = 68/203 (33%), Positives = 98/203 (48%), Gaps = 15/203 (7%) Frame = -2 Query: 721 NPLHG--ARKEGTVGKPLPRVEAKIIMDDG------TETKDGV-GELCIKSP--SLFKEY 575 +PL G A K G+ PLP + AKI+ D G TE V G L + P S+ + Sbjct: 424 SPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGI 483 Query: 574 WKRPEVTAES----FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEA 407 W P S F D G++ GD +D DG +LGR + D+M V G+++S E+E+ Sbjct: 484 WGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRID-DVMNVSGHRISTAEVES 542 Query: 406 VLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKL 227 L+ H V E AV+G+ DE + ICA +V RA A T E L + + Sbjct: 543 ALVAHSGVAEAAVVGVTDETTTQAICAFVV------LRANYAPHDR-TAEELRTEVARVI 595 Query: 226 APYKIPTRLHLWDSLPRNAMGKV 158 +P P +H+ LP+ GK+ Sbjct: 596 SPIARPRDVHVVPELPKTRSGKI 618
>ACSA_MYCBO (P59871) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 87.4 bits (215), Expect = 4e-17 Identities = 68/203 (33%), Positives = 98/203 (48%), Gaps = 15/203 (7%) Frame = -2 Query: 721 NPLHG--ARKEGTVGKPLPRVEAKIIMDDG------TETKDGV-GELCIKSP--SLFKEY 575 +PL G A K G+ PLP + AKI+ D G TE V G L + P S+ + Sbjct: 424 SPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGI 483 Query: 574 WKRPEVTAES----FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEA 407 W P S F D G++ GD +D DG +LGR + D+M V G+++S E+E+ Sbjct: 484 WGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRID-DVMNVSGHRISTAEVES 542 Query: 406 VLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKL 227 L+ H V E AV+G+ DE + ICA +V RA A T E L + + Sbjct: 543 ALVAHSGVAEAAVVGVTDETTTQAICAFVV------LRANYAPHDR-TAEELRTEVARVI 595 Query: 226 APYKIPTRLHLWDSLPRNAMGKV 158 +P P +H+ LP+ GK+ Sbjct: 596 SPIARPRDVHVVPELPKTRSGKI 618
>ACS1_DEBHA (Q6BQF2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 671 Score = 87.0 bits (214), Expect = 5e-17 Identities = 61/188 (32%), Positives = 96/188 (51%), Gaps = 7/188 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKS--PSLFKEYWKRPEVTAESFID 536 K G+ P ++AKI+ G E K D G LC+KS PS+ + + E+++ Sbjct: 451 KPGSASLPCFGIDAKILDPVSGKELKENDVEGVLCVKSCWPSISRGIYNDYARFIETYLK 510 Query: 535 G--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 + +GD D DG++ ILGR + D++ V G++LS EIEA L+ H++V ECAV+G Sbjct: 511 PYPNHYFSGDGAARDVDGFYWILGRVD-DVVNVSGHRLSTAEIEAALILHESVAECAVVG 569 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 DE G+ + A + K + E E K L + ++ P+ P + L D L Sbjct: 570 YADELTGQAVAAYVSLKSNVSEDLEVIKK------ELILTVRKEIGPFATPKTILLVDDL 623 Query: 181 PRNAMGKV 158 P+ GK+ Sbjct: 624 PKTRSGKI 631
>MENE_LISIN (Q92AY8) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 87.0 bits (214), Expect = 5e-17 Identities = 63/187 (33%), Positives = 92/187 (49%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFI 539 P K G+ GK L E KI D GE+ +K PS+ Y + TA++FI Sbjct: 293 PKDALNKIGSSGKALFPAEVKIADD---------GEILLKGPSITPGYLHNEKATAKAFI 343 Query: 538 DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 D G+FKTGD +DE+G+ +L R +D++ GG + EIE V+ ++ V E AV+G Sbjct: 344 D-GWFKTGDIGYLDEEGFLFVLER-RSDLIISGGENIYPTEIEHVIGAYEAVEEVAVVGK 401 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 D +G V A IV E E L + LA +KIP ++ + + LP Sbjct: 402 SDAKWGSVPVAFIVVNEGFDE------------GVLKDICQTNLASFKIPKQITIVEHLP 449 Query: 178 RNAMGKV 158 + A GK+ Sbjct: 450 KTASGKI 456
>LUCI_LUCLA (Q01158) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 86.7 bits (213), Expect = 7e-17 Identities = 49/133 (36%), Positives = 75/133 (56%), Gaps = 2/133 (1%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFID 536 G K G GK +P +AK+I D +T + GE+C+K P L K Y PE T E + Sbjct: 357 GDDKPGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDE 416 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD DE+ +F I+ R + ++K GY++ E+E+VLL+H + + V G+P Sbjct: 417 EGWLHTGDIGYYDEEKHFFIVDRLKS-LIKYKGYQVPPAELESVLLQHPNIFDAGVAGVP 475 Query: 355 DEAYGEVICAIIV 317 D GE+ A++V Sbjct: 476 DPIAGELPGAVVV 488
>GRSA_ANEMI (P0C061) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 86.3 bits (212), Expect = 9e-17 Identities = 57/186 (30%), Positives = 91/186 (48%), Gaps = 8/186 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKD--GVGELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 +G P+ + I+ D+ + K GELCI L + YWKRPE+T++ F+D F Sbjct: 348 IGAPIQNTQIYIV-DENLQLKSVGEAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGE 406 Query: 526 --FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 +KTGD DG LGR + + K+ G+++ E+E++LL+H + E AV D Sbjct: 407 KLYKTGDQARWLSDGNIEYLGRIDNQV-KIRGHRVELEEVESILLKHMYISETAVSVHKD 465 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 +CA V S+ + LE L +S ++L Y IP+ D +P Sbjct: 466 HQEQPYLCAYFV------------SEKHIPLEQLRQFSSEELPTYMIPSYFIQLDKMPLT 513 Query: 172 AMGKVN 155 + GK++ Sbjct: 514 SNGKID 519
>LUCI_LUCCR (P13129) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 86.3 bits (212), Expect = 9e-17 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 2/133 (1%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFID 536 G K G GK +P +AK+I D ++ + GE+C+K P L K Y PE T E + Sbjct: 357 GDDKPGASGKVVPLFKAKVIDLDTKKSLGPNRRGEVCVKGPMLMKGYVNNPEATKELIDE 416 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD DE+ +F I+ R + ++K GY++ E+E+VLL+H ++ + V G+P Sbjct: 417 EGWLHTGDIGYYDEEKHFFIVDRLKS-LIKYKGYQVPPAELESVLLQHPSIFDAGVAGVP 475 Query: 355 DEAYGEVICAIIV 317 D GE+ A++V Sbjct: 476 DPVAGELPGAVVV 488
>GRSB_ANEMI (P0C063) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4450 Score = 86.3 bits (212), Expect = 9e-17 Identities = 63/189 (33%), Positives = 94/189 (49%), Gaps = 7/189 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF- 527 +E T+G+PL V+ I+ + GV GELCI L + Y +PE+TA+ F+ F Sbjct: 3895 QEITIGRPLSNVDVYIVNCNHQLQPVGVVGELCIGGQGLARGYLNKPELTADKFVVNPFV 3954 Query: 526 -----FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 +KTGD DG +GR + + KV GY++ EIE+ +LE++ + E V+ Sbjct: 3955 PGERMYKTGDLAKWRSDGMIEYVGRVDEQV-KVRGYRIELGEIESAILEYEKIKEAVVMV 4013 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 A +++CA IV +ED LTL+ L S+ L Y IP DS+ Sbjct: 4014 SEHTASEQMLCAYIVGEED-----------VLTLD-LRSYLAKLLPSYMIPNYFIQLDSI 4061 Query: 181 PRNAMGKVN 155 P GKV+ Sbjct: 4062 PLTPNGKVD 4070 Score = 69.7 bits (169), Expect = 9e-12 Identities = 50/185 (27%), Positives = 83/185 (44%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GK + I+ G GV GELC+ + + Y +P +T E F+ F Sbjct: 1815 IGKAISNSTVYIMDRYGQLQPVGVPGELCVGGDGVARGYMNQPALTEEKFVPNPFAPGER 1874 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + K+ GY++ EIE +L++H V E ++ + D Sbjct: 1875 MYRTGDLARWLPDGTIEYLGRIDQQV-KIRGYRIEPGEIETLLVKHKKVKESVIMVVEDN 1933 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + +CA VP+E+ +T+ L + +L Y +P + +P Sbjct: 1934 NGQKALCAYYVPEEE------------VTVSELREYIAKELPVYMVPAYFVQIEQMPLTQ 1981 Query: 169 MGKVN 155 GKVN Sbjct: 1982 NGKVN 1986 Score = 68.9 bits (167), Expect = 1e-11 Identities = 55/189 (29%), Positives = 86/189 (45%), Gaps = 19/189 (10%) Frame = -2 Query: 718 PLHGARKEGTV--GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAE 548 PL GTV GKP ++ I+ GV GELCI + + Y RP++TAE Sbjct: 2850 PLSSLHVTGTVPIGKPYANMKMYIMNQYLQIQPVGVIGELCIGGAGVARGYLNRPDLTAE 2909 Query: 547 SFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 F+ F ++TGD DG LGR + + K+ G ++ EIEA L +HD+ Sbjct: 2910 KFVPNPFVPGEKLYRTGDLARWMPDGNVEFLGRNDHQV-KIRGIRIELGEIEAQLRKHDS 2968 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKED----------ARERAEQASKPALTLEALTSWSK 236 + E V+ D + +CA +V + + A +RA ++LEA+ + Sbjct: 2969 IKEATVIAREDHMKEKYLCAYMVTEGEVNVAELRAYLANDRAAMIPSYFVSLEAMPLTAN 3028 Query: 235 DKLAPYKIP 209 K+ +P Sbjct: 3029 GKIDKRSLP 3037 Score = 61.2 bits (147), Expect = 3e-09 Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP+ I+ + G VGEL I ++ + Y E+TAE F F Sbjct: 780 IGKPISNTWIYILDQEQQLQPQGIVGELYISGANVGRGYLNNQELTAEKFFADPFRPNER 839 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + K+ G+++ EIEA LL V E V+ D+ Sbjct: 840 MYRTGDLARWLPDGNIEFLGRADHQV-KIRGHRIELGEIEAQLLNCKGVKEAVVIDKADD 898 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 G+ +CA +V + + + L + L Y IP+ D LP Sbjct: 899 KGGKYLCAYVVMEVEVND------------SELREYLGKALPDYMIPSFFVPLDQLPLTP 946 Query: 169 MGKVN 155 GK++ Sbjct: 947 NGKID 951
>TYCB_BREPA (O30408) Tyrocidine synthetase 2 (Tyrocidine synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D Length = 3587 Score = 85.9 bits (211), Expect = 1e-16 Identities = 60/187 (32%), Positives = 94/187 (50%), Gaps = 8/187 (4%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETK--DGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF--- 527 T+GKP+ + I+ DD + K +GELCI SL + YW RPE+TAE F+D F Sbjct: 2849 TIGKPIQNTKLYIV-DDQLQLKAPGQMGELCISGLSLARGYWNRPELTAEKFVDNPFVPG 2907 Query: 526 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 ++TGD DG LGR + + K+ G+++ E+E+VLL +DTV E A + Sbjct: 2908 TKMYRTGDLARWLPDGTIEYLGRIDHQV-KIRGHRVELGEVESVLLRYDTVKEAAAITHE 2966 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D+ +CA V AE + PA L ++ +++L Y +P + +P Sbjct: 2967 DDRGQAYLCAYYV--------AEGEATPA----QLRAYMENELPNYMVPAFFIQLEKMPL 3014 Query: 175 NAMGKVN 155 K++ Sbjct: 3015 TPNDKID 3021 Score = 78.6 bits (192), Expect = 2e-14 Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 7/186 (3%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG------ 533 T+G+P+ I+ GV GE+CI L + YWK+PE+TAE F+ Sbjct: 1816 TIGRPIANTAIYIVDQHHQLLPVGVVGEICIGGHGLARGYWKKPELTAEKFVANPAVPGE 1875 Query: 532 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 +KTGD DG +GR + D +KV GY++ EIEAVLL +D E V+ D Sbjct: 1876 RMYKTGDLGRWLHDGTIDFIGRVD-DQIKVRGYRIEVGEIEAVLLAYDQTNEAIVVAYQD 1934 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 + + A + K A+ L + +L Y +PT L D+ P Sbjct: 1935 DRGDSYLAAYV------------TGKTAIEESELRAHLLRELPAYMVPTYLIQLDAFPLT 1982 Query: 172 AMGKVN 155 GKV+ Sbjct: 1983 PNGKVD 1988 Score = 75.1 bits (183), Expect = 2e-13 Identities = 54/186 (29%), Positives = 90/186 (48%), Gaps = 8/186 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDG--VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 +GKP+ I+D+G + K VGEL I ++ + Y +PE+TAE F+D + Sbjct: 782 IGKPISNTGI-YILDEGLQLKPEGIVGELYISGANVGRGYLHQPELTAEKFLDNPYQPGE 840 Query: 526 --FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 ++TGD DG LGR + + K+ G+++ EIE+ LL H + E V+ D Sbjct: 841 RMYRTGDLALWLPDGQLEFLGRIDHQV-KIRGHRIELGEIESRLLNHPAIKEAVVIDRAD 899 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 E G+ +CA +V ++ AL+ E + ++ L Y IP+ + +P Sbjct: 900 ETGGKFLCAYVVLQK------------ALSDEEMRAYLAQALPEYMIPSFFVTLERIPVT 947 Query: 172 AMGKVN 155 GK + Sbjct: 948 PNGKTD 953
>CAIC_SHIFL (Q83MG9) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 85.9 bits (211), Expect = 1e-16 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFID 536 R+ ++G+ EA+I D G +GE+CIK ++FKEY+ P+ TA+ Sbjct: 342 RRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEA 401 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGDT DE+G+F + R +++K GG +S +E+E ++ H + + V+G+ Sbjct: 402 DGWLHTGDTGYRDEEGFFYFVDR-RCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIK 460 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D E I A +V E L+ E + + +A +K+P+ L + LPR Sbjct: 461 DSIRDEAIKAFVVLNEG----------ETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPR 510 Query: 175 NAMGKV 158 N GK+ Sbjct: 511 NCSGKI 516
>LGRC_BREPA (Q70LM5) Linear gramicidin synthetase subunit C [Includes:| ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tr Length = 7756 Score = 85.9 bits (211), Expect = 1e-16 Identities = 59/188 (31%), Positives = 93/188 (49%), Gaps = 9/188 (4%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 ++G+P+ V+ I+ + GV GEL I SL + Y+KRP++T E F+D F Sbjct: 7006 SIGRPIDNVQVYILDEQRQPVPIGVTGELYIAGSSLARGYYKRPDLTQERFVDNPFTANR 7065 Query: 526 ----FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 ++TGD V DG +GR++ D + + G+++ EIE+VL +H V E VL Sbjct: 7066 GAKMYRTGDLVRYLPDGQIEFIGRSD-DQVSIRGFRVELGEIESVLYQHPAVKEAIVLAR 7124 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 D + + A +V ED E+A+ L + K+KL Y +P +LP Sbjct: 7125 EDMPGVKRLAAYVVVAEDDAEQADD----------LRGYLKEKLPEYMVPAAFVTLKALP 7174 Query: 178 RNAMGKVN 155 GKV+ Sbjct: 7175 LTPNGKVD 7182 Score = 79.3 bits (194), Expect = 1e-14 Identities = 58/190 (30%), Positives = 88/190 (46%), Gaps = 8/190 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF- 527 K +G+PL ++ + GV GEL I L + YW RPE+TAE FI F Sbjct: 3364 KSAPIGRPLANATLYVLDANQKPVPVGVPGELYIGGKGLARGYWNRPELTAERFIAHPFG 3423 Query: 526 ------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 ++TGD V DG LGR + + K+ GY++ EIE+ L +H + E V+ Sbjct: 3424 AKGERLYRTGDLVRYLPDGNLEFLGRIDTQV-KIRGYRIELGEIESALSQHPAIQEAVVI 3482 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 A+ + + A +V +A+ AE+ L + K+ L Y IP D+ Sbjct: 3483 -----AWEQRLAAYMVAAGEAQPAAEE----------LARYLKETLPDYMIPAGFVFMDA 3527 Query: 184 LPRNAMGKVN 155 +P GKV+ Sbjct: 3528 IPLTVNGKVD 3537 Score = 69.7 bits (169), Expect = 9e-12 Identities = 56/188 (29%), Positives = 84/188 (44%), Gaps = 9/188 (4%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 ++G+P+ V+ ++ + GV GEL I SL + Y RP++T E FI + Sbjct: 4422 SIGRPIDNVQVYVLDEKLQPVPIGVAGELYIAGDSLARGYLHRPDLTRERFIANPYGQKA 4481 Query: 526 ----FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 +KTGD V DG +GR + D + + G+++ EIE L H V E VL Sbjct: 4482 GARMYKTGDLVRYLPDGNIEFIGRAD-DQVSIRGFRVELGEIETALYSHPAVKETIVLVR 4540 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 D + + A IV +E +A QA S+ K+ L Y +P LP Sbjct: 4541 EDMPGMKRLVAYIVQREGQEGQAVQAGD-------FRSYLKELLPEYMVPAAFVFMADLP 4593 Query: 178 RNAMGKVN 155 GKV+ Sbjct: 4594 LTPNGKVD 4601 Score = 68.9 bits (167), Expect = 1e-11 Identities = 55/187 (29%), Positives = 82/187 (43%), Gaps = 9/187 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G+P+ ++ + GV GEL I L Y PE+TAE F+D F Sbjct: 1847 IGRPISNTTVYVLDKNRQPVPLGVAGELYIGGDGLASGYLNNPELTAERFVDNPFDPQKA 1906 Query: 526 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 ++TGD V DG +GR + + K+ G+++ EIE LL H V E ++ Sbjct: 1907 SRLYRTGDLVRYLPDGAIEFIGRIDNQV-KIRGFRIELGEIETALLRHPAVQEAFLMVRE 1965 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D + + A +V Q +P + S+ KDKL Y IP+ DS P Sbjct: 1966 DAPGDKRLAAYLV------FAGGQTVEPV----EMRSYLKDKLPEYMIPSAFVQMDSFPL 2015 Query: 175 NAMGKVN 155 GKV+ Sbjct: 2016 TPNGKVD 2022 Score = 66.2 bits (160), Expect = 1e-10 Identities = 53/190 (27%), Positives = 84/190 (44%), Gaps = 8/190 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI----- 539 K +G+P+ ++ GV GEL I + + YW RPE+TAE FI Sbjct: 5943 KNPPIGRPIANTTVYVLDAHLQPVPIGVPGELYIGGKGVARGYWNRPELTAERFIADPFG 6002 Query: 538 --DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 D ++TGD V E+G LGR + D +K+ GY++ EIE L +H V V+ Sbjct: 6003 QADERLYRTGDLVRYLENGELEFLGRID-DQVKIRGYRIELGEIENALRQHPAVQNVVVI 6061 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 + A + + A +V ++ ++A L + K L Y +P + Sbjct: 6062 ARQEGAGDKRLAAYLVAA--TGQQPDEAE--------LVRYLKSTLPEYMVPAGYVWLEK 6111 Query: 184 LPRNAMGKVN 155 +P GKV+ Sbjct: 6112 IPLTVNGKVD 6121 Score = 66.2 bits (160), Expect = 1e-10 Identities = 51/188 (27%), Positives = 85/188 (45%), Gaps = 10/188 (5%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G+P+ ++ G GEL I L Y E+TAE F++ F Sbjct: 782 IGRPISNTTVYVLDKHKQPVPYGAAGELYIGGDGLALGYLNNAELTAERFVENPFDPQKG 841 Query: 526 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 ++TGD V +G +GR + + K+ G+++ E+EA L H V E V+ Sbjct: 842 SRLYRTGDLVRYLPNGTIEFIGRIDNQV-KIRGFRIELGEVEAALALHPEVSETVVMARE 900 Query: 355 DEAYGEVICAII-VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 ++ + + A + V K+DA E A+ L +W K KL Y +P+ D++P Sbjct: 901 NDRGEKHLTAYVTVAKDDAPEVAD-----------LQAWLKTKLPEYMVPSAYVFLDAMP 949 Query: 178 RNAMGKVN 155 A GK++ Sbjct: 950 LTANGKID 957
>CAIC_ECO57 (Q8XA34) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 85.5 bits (210), Expect = 2e-16 Identities = 49/157 (31%), Positives = 82/157 (52%), Gaps = 3/157 (1%) Frame = -2 Query: 619 VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 449 +GE+CIK ++FKEY+ P+ TA+ G+ TGDT DE+G+F + R +++ Sbjct: 371 IGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFIDR-RCNMI 429 Query: 448 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 269 K GG +S +E+E ++ H + + V+G+ D E I A +V E Sbjct: 430 KRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEG----------ET 479 Query: 268 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 L+ E + + +A +K+P+ L + LPRN GK+ Sbjct: 480 LSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKI 516
>ACSA_PENCH (P36333) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 669 Score = 85.1 bits (209), Expect = 2e-16 Identities = 61/188 (32%), Positives = 93/188 (49%), Gaps = 7/188 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET---KDGVGELCIKSP--SLFKEYWKRPEVTAESFID 536 K G+ P +E II E D G L K P S+ + W + +++++ Sbjct: 450 KPGSASLPFFGIEPAIIDPVSGEEIVGNDVEGVLAFKQPWPSMARTVWGAHKRYMDTYLN 509 Query: 535 --GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 G++ TGD D DGY+ I GR + D++ V G++LS EIEA LLEH +V E AV+G Sbjct: 510 VYKGYYFTGDGAGRDHDGYYWIRGRVD-DVVNVSGHRLSTAEIEAALLEHPSVAEAAVVG 568 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 + DE G+ + A + KE + EQ SK L + + P+ P + + D L Sbjct: 569 IADELTGQAVNAFVSLKEG--KPTEQISKD------LAMQVRKSIGPFAAPKAVFVVDDL 620 Query: 181 PRNAMGKV 158 P+ GK+ Sbjct: 621 PKTRSGKI 628
>ACS2_ASHGO (Q750T7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 687 Score = 85.1 bits (209), Expect = 2e-16 Identities = 65/206 (31%), Positives = 100/206 (48%), Gaps = 19/206 (9%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKII---MDDGTETKDGVGELCIKSP--SLFKEYWKRPE 560 PL GA K G+ P + A II D E D G L IKSP S+ + W + Sbjct: 439 PLAGAIPTKPGSATVPFFGINACIIDPVTGDELEGNDVEGVLAIKSPWPSMARSVWNNHD 498 Query: 559 VTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E+++ G++ TGD D DGY+ I GR + D++ V G++LS EIEA L EH+ Sbjct: 499 RYIETYLKPYPGYYFTGDGAGRDHDGYYWIRGRVD-DVVNVSGHRLSTAEIEAALSEHEG 557 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKP------ALTLEA----LTSWSK 236 V + AV+G+ DE G+ + A + KE + + P + L+ L + Sbjct: 558 VSQAAVVGIADELTGQAVVAFVSLKEGYGRGSSTDTDPESIAPDVVPLDTLRRELVLQVR 617 Query: 235 DKLAPYKIPTRLHLWDSLPRNAMGKV 158 ++ P+ P + + D LP+ GK+ Sbjct: 618 AEIGPFAAPKSVIVVDDLPKTRSGKI 643
>CAIC_ECOL6 (Q8FLA5) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 85.1 bits (209), Expect = 2e-16 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFID 536 R+ ++G+ EA+I D G +GE+CIK ++FKEY+ P+ TA+ Sbjct: 342 RRWPSIGRAGFCYEAEIRDDHNRPLPAGELGEICIKGVPGKTIFKEYFLNPKATAKVLEA 401 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGDT DE+G+F + R +++K GG +S +E+E ++ H + + V+G+ Sbjct: 402 DGWLHTGDTGYRDEEGFFYFVDR-RCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIK 460 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D E I A +V E L+ E + + +A +K+P+ L + LPR Sbjct: 461 DSIRDEAIKAFVVLNEG----------ETLSEEEFFCFCEQNMAKFKVPSYLEIRKDLPR 510 Query: 175 NAMGKV 158 N GK+ Sbjct: 511 NCSGKI 516
>MENE_LACLA (Q9CHK3) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 451 Score = 84.7 bits (208), Expect = 3e-16 Identities = 61/182 (33%), Positives = 90/182 (49%), Gaps = 1/182 (0%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYW-KRPEVTAESFIDGGFF 524 K +VG+PLP VE +I D GVGE+ +KSP L K Y ++P TA F Sbjct: 290 KTSSVGRPLPGVEIEIRQADLA----GVGEIWLKSPMLMKAYLGQKPYGTA--------F 337 Query: 523 KTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAY 344 +TGD +D DG+ +L R DI+ GG + EIE ++ + ECA++ PD + Sbjct: 338 ETGDIGYLDTDGFLYLLNRRK-DIIISGGENIYPKEIEDLVYSLPEIKECALVAKPDAKW 396 Query: 343 GEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMG 164 G+V + ++ E L ++ +KLA YK P + D LP+NA G Sbjct: 397 GQVPILFVSGN--------------ISQEKLENFLTEKLAKYKRPQSITFMDELPKNASG 442 Query: 163 KV 158 K+ Sbjct: 443 KI 444
>ACS2_DEBHA (Q6BS00) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 679 Score = 84.7 bits (208), Expect = 3e-16 Identities = 50/163 (30%), Positives = 92/163 (56%), Gaps = 7/163 (4%) Frame = -2 Query: 625 DGVGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNA 458 D G L +K PS+ + +K +++++ G++ TGD D DGY+ I GR + Sbjct: 476 DVEGVLAVKDTWPSMARSVYKNHTKYMDTYLNPYPGYYFTGDGAARDHDGYYWIRGRVD- 534 Query: 457 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED--ARERAEQ 284 D++ V G++LS EIEA L+EH+ + E AV+G+ D+ G+ + A + KE A +A++ Sbjct: 535 DVVNVSGHRLSTAEIEAALIEHNAISEAAVVGMNDDLTGQTVVAFVALKEHLIANLKADE 594 Query: 283 ASKPALTL-EALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 + + AL L + + + ++ P+ P + + + LP+ GK+ Sbjct: 595 SPEEALKLKKEMILQVRTQIGPFAAPKSVIIVEDLPKTRSGKI 637
>GRSB_BREBE (P0C064) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4449 Score = 84.3 bits (207), Expect = 3e-16 Identities = 63/189 (33%), Positives = 93/189 (49%), Gaps = 7/189 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF- 527 +E T+G PL V+ I+ + GV GELCI L + Y +PE+TA+ F+ F Sbjct: 3894 QEITIGCPLSNVDVYIVNCNHQLQPVGVVGELCIGGQGLARGYLNKPELTADKFVVNPFV 3953 Query: 526 -----FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 +KTGD DG +GR + + KV GY++ EIE+ +LE++ + E V+ Sbjct: 3954 PGERMYKTGDLAKWRSDGMIEYVGRVDEQV-KVRGYRIELGEIESAILEYEKIKEAVVIV 4012 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 A +++CA IV +ED LTL+ L S+ L Y IP DS+ Sbjct: 4013 SEHTASEQMLCAYIVGEED-----------VLTLD-LRSYLAKLLPSYMIPNYFIQLDSI 4060 Query: 181 PRNAMGKVN 155 P GKV+ Sbjct: 4061 PLTPNGKVD 4069 Score = 69.7 bits (169), Expect = 9e-12 Identities = 50/185 (27%), Positives = 83/185 (44%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GK + I+ G GV GELC+ + + Y +P +T E F+ F Sbjct: 1815 IGKAISNSTVYIMDRYGQLQPVGVPGELCVGGDGVARGYMNQPALTEEKFVPNPFAPGER 1874 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + K+ GY++ EIE +L++H V E ++ + D Sbjct: 1875 MYRTGDLARWLPDGTIEYLGRIDQQV-KIRGYRIEPGEIETLLVKHKKVKESVIMVVEDN 1933 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + +CA VP+E+ +T+ L + +L Y +P + +P Sbjct: 1934 NGQKALCAYYVPEEE------------VTVSELREYIAKELPVYMVPAYFVQIEQMPLTQ 1981 Query: 169 MGKVN 155 GKVN Sbjct: 1982 NGKVN 1986 Score = 68.2 bits (165), Expect = 3e-11 Identities = 55/197 (27%), Positives = 89/197 (45%), Gaps = 9/197 (4%) Frame = -2 Query: 718 PLHGARKEGTV--GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAE 548 PL GTV GKP ++ I+ GV GELCI + + Y RP++TAE Sbjct: 2848 PLSSLHVTGTVPIGKPYANMKMYIMNQYLQIQPVGVIGELCIGGAGVARGYLNRPDLTAE 2907 Query: 547 SFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 F+ F ++TGD DG LGR + + K+ G ++ EIEA L +HD+ Sbjct: 2908 KFVPNPFVPGEKLYRTGDLARWMPDGNVEFLGRNDHQV-KIRGIRIELGEIEAQLRKHDS 2966 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E V+ D + +CA +V + + + + L ++ L IP+ Sbjct: 2967 IKEATVIAREDHMKEKYLCAYMVTEGE------------VNVAELRAYLATDLPAAMIPS 3014 Query: 205 RLHLWDSLPRNAMGKVN 155 +++P A GK++ Sbjct: 3015 YFVSLEAMPLTANGKID 3031 Score = 61.2 bits (147), Expect = 3e-09 Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP+ I+ + G VGEL I ++ + Y E+TAE F F Sbjct: 780 IGKPISNTWIYILDQEQQLQPQGIVGELYISGANVGRGYLNNQELTAEKFFADPFRPNER 839 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + K+ G+++ EIEA LL V E V+ D+ Sbjct: 840 MYRTGDLARWLPDGNIEFLGRADHQV-KIRGHRIELGEIEAQLLNCKGVKEAVVIDKADD 898 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 G+ +CA +V + + + L + L Y IP+ D LP Sbjct: 899 KGGKYLCAYVVMEVEVND------------SELREYLGKALPDYMIPSFFVPLDQLPLTP 946 Query: 169 MGKVN 155 GK++ Sbjct: 947 NGKID 951
>ACSA_SYNY3 (Q55404) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 84.0 bits (206), Expect = 4e-16 Identities = 64/203 (31%), Positives = 97/203 (47%), Gaps = 16/203 (7%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKSP--SLFKE-------- 578 PL GA K G+ KP P + A+I+ DG + D G L IK P S+ ++ Sbjct: 430 PLPGAIPTKPGSCTKPFPGIVAEIVDLDGNPVESDQGGFLVIKQPWPSMIRDVYGDTDRF 489 Query: 577 ---YWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEA 407 YW+ + ++ + GD D+DGYF ++GR + D++ V G++L +EIE+ Sbjct: 490 RHTYWEHIQPKEGQYL----YFAGDGARRDKDGYFWVMGRVD-DVINVSGHRLGTMEIES 544 Query: 406 VLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKL 227 L+ H V E AV+G PDE GE I A V E E +E+ K L +++ Sbjct: 545 ALVSHPLVAEAAVVGRPDELTGEAIFA-FVSLEGNAEPSEELKKD------LVKHVTEEI 597 Query: 226 APYKIPTRLHLWDSLPRNAMGKV 158 P + D LP+ GK+ Sbjct: 598 GAIARPAEIRFTDVLPKTRSGKI 620
>ACS2_KLULA (Q9Y7B5) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 684 Score = 84.0 bits (206), Expect = 4e-16 Identities = 66/201 (32%), Positives = 98/201 (48%), Gaps = 14/201 (6%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKSP--SLFKEYWKRPE 560 PL GA K G+ P + A II G E K D G L +KSP S+ + W Sbjct: 440 PLAGAVPTKPGSATVPFFGINACIIDPVSGEELKGNDVEGVLAVKSPWPSMARSVWNNHA 499 Query: 559 VTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E+++ G++ TGD D DGY+ I GR + D++ V G++LS EIEA L EH+ Sbjct: 500 RYFETYLKPYPGYYFTGDGAGRDHDGYYWIRGRVD-DVVNVSGHRLSTAEIEAALAEHEG 558 Query: 385 VLECAVLGLPDEAYGEVICAIIVPK-----EDARERAEQASKPALTLEALTSWSKDKLAP 221 V E AV+G+ DE G+ + A + K E+A E P L + ++ P Sbjct: 559 VSEAAVVGITDELTGQAVIAFVSLKDGYLSENAVEGDSTHISPDNLRRELILQVRGEIGP 618 Query: 220 YKIPTRLHLWDSLPRNAMGKV 158 + P + + + LP+ GK+ Sbjct: 619 FAAPKTVVVVNDLPKTRSGKI 639
>ACSA_SCHPO (P78773) Probable acetyl-coenzyme A synthetase (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) Length = 662 Score = 84.0 bits (206), Expect = 4e-16 Identities = 60/189 (31%), Positives = 97/189 (51%), Gaps = 8/189 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGT----ETKDGVGELCIKSP--SLFKEYWKRPEVTAESFI 539 K G+ P ++A +I+D T E D G L I+SP S + W+ + ++++ Sbjct: 441 KPGSATLPFFGIDA-VIIDPLTGKIIEGNDVEGVLAIRSPWPSAARTVWRGHDRYIDTYL 499 Query: 538 DG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 GF+ TGD T D+DGY I GR + D++ + G++LS EIEA LL HD V E AV+ Sbjct: 500 KPYPGFYFTGDGATRDKDGYIWIRGRVD-DVVNISGHRLSTAEIEAALLSHDAVAESAVV 558 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G+ DE G+ + A I+ K E + + + + + P+ P +L ++ Sbjct: 559 GVHDELTGQAVNAFILLKPGYEATVELEKELIMAV-------RSTIGPFASPRKL-IFSD 610 Query: 184 LPRNAMGKV 158 LP+ GK+ Sbjct: 611 LPKTRSGKI 619
>LGRB_BREPA (Q70LM6) Linear gramicidin synthetase subunit B [Includes:| ATP-dependent alanine adenylase (AlaA) (Alanine activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-depende Length = 5162 Score = 84.0 bits (206), Expect = 4e-16 Identities = 60/195 (30%), Positives = 95/195 (48%), Gaps = 10/195 (5%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI-- 539 GA+ E T+G+PL +A ++ G+ GEL + L + Y KRP++TAE F+ Sbjct: 3339 GAKTEPTIGRPLANTQAYVLDAKLQPVPLGLPGELYLGGDGLARGYLKRPKMTAERFLPN 3398 Query: 538 ------DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLE 377 D + TGD V DG LGR + + K+ GY++ E+EAVL H + E Sbjct: 3399 PFHPDPDARMYSTGDLVRYLPDGQLEYLGRIDHQV-KIRGYRIELGELEAVLRSHPQIKE 3457 Query: 376 CAVLGLPDEAYGEVICAIIVPKE-DARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL 200 V+ D+ + + A I K+ + +RA LTSW+K KL + +P+ Sbjct: 3458 AVVVAKEDKLGEKRLVAYITTKDGECGDRA-----------VLTSWAKAKLPEFMVPSFF 3506 Query: 199 HLWDSLPRNAMGKVN 155 D++P GK++ Sbjct: 3507 VWLDAMPLTPNGKID 3521 Score = 73.6 bits (179), Expect = 6e-13 Identities = 49/185 (26%), Positives = 81/185 (43%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKPL ++ I+ G GV GELCI SL + YW +T E F+ F Sbjct: 773 IGKPLANIQTHIVNKHGQLQPVGVPGELCIAGASLARGYWNNEALTNEKFVPHPFAAGQR 832 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD +DG LGR + + K+ GY++ EI A L++ ++ + V+ D Sbjct: 833 MYRTGDLARYRQDGNIEYLGRIDHQV-KIRGYRIELDEIRAQLIQEASIRDAVVIARTDH 891 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 +CA + + T+ AL + L Y +P+ + P + Sbjct: 892 NGQAYLCAYFIADKQ------------WTVNALREALRQTLPDYMVPSHFIQMEEFPLTS 939 Query: 169 MGKVN 155 GK++ Sbjct: 940 SGKID 944 Score = 71.2 bits (173), Expect = 3e-12 Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 10/198 (5%) Frame = -2 Query: 718 PLHGARKEG-TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAES 545 P+ G R+ T+G+P+ V ++ ++ GV GEL I SL + Y RP++T S Sbjct: 1820 PVLGERESAPTIGRPIDNVSVYVLDENRQPVPVGVVGELYIGGKSLARGYRNRPDLTEAS 1879 Query: 544 FIDGGF--------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 F+ F ++TGD V DG +GR + D + + G+++ EIE+ L H Sbjct: 1880 FVPNPFSPIEGARMYRTGDLVRYAADGSIEFIGRAD-DQVSIRGFRVELGEIESALYAHP 1938 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIP 209 V E V+ D G + ER + +L K+ L Y +P Sbjct: 1939 AVAESVVIVREDVTPGVKRLVAYAVLHEGEERQTSELRQSL---------KEMLPDYMVP 1989 Query: 208 TRLHLWDSLPRNAMGKVN 155 + + L ++LP GKV+ Sbjct: 1990 SAIVLMEALPLTPNGKVD 2007 Score = 64.7 bits (156), Expect = 3e-10 Identities = 52/187 (27%), Positives = 84/187 (44%), Gaps = 9/187 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G+P+ A ++ GV GEL I L + Y RP++TAE F+ F Sbjct: 4406 IGRPIKNTTAYVLDRHMQPVPIGVTGELYIGGDGLAEGYLNRPDLTAERFVPNPFATDQA 4465 Query: 526 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 ++TGD V DG +GR + + K+ G+++ E+EAVL +H + V+ Sbjct: 4466 ARLYRTGDLVRYLPDGLIEFIGRLDNQV-KIRGFRIELSEVEAVLAKHPAITASVVIVHE 4524 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 +EA + + A V +DA + A L K + Y +P + D+LP Sbjct: 4525 NEAGMKQLVAYAV--KDAEQELGTAE--------LRQHFKAHVPDYMVPAAFVMLDALPL 4574 Query: 175 NAMGKVN 155 GKV+ Sbjct: 4575 TPNGKVD 4581
>CAIC_ECOLI (P31552) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 83.2 bits (204), Expect = 8e-16 Identities = 53/173 (30%), Positives = 87/173 (50%), Gaps = 4/173 (2%) Frame = -2 Query: 664 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 497 EA+I D G +GE+CIK ++FKEY+ P+ TA+ G+ TGDT D Sbjct: 355 EAEIRDDHNRPLPAGEIGEICIKGIPGKTIFKEYFLNPQATAKVLEADGWLHTGDTGYRD 414 Query: 496 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 317 E+ +F + R +++K GG +S +E+E ++ H + + V+G+ D E I A +V Sbjct: 415 EEDFFYFVDR-RCNMIKRGGENVSCVELENIIAAHPKIQDIVVVGIKDSIRDEAIKAFVV 473 Query: 316 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 E L+ E + + +A +K+P+ L + LPRN GK+ Sbjct: 474 LNEG----------ETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKI 516
>ACS2_YEAST (P52910) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 82.4 bits (202), Expect = 1e-15 Identities = 65/202 (32%), Positives = 98/202 (48%), Gaps = 15/202 (7%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKIIMDDGT----ETKDGVGELCIKSP--SLFKEYWKRP 563 PL GA K G+ P + A II D T E D G L +KSP S+ + W Sbjct: 439 PLAGAVPTKPGSATVPFFGINACII-DPVTGVELEGNDVEGVLAVKSPWPSMARSVWNHH 497 Query: 562 EVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 + ++++ G + TGD D DGY+ I GR + D++ V G++LS EIEA + H+ Sbjct: 498 DRYMDTYLKPYPGHYFTGDGAGRDHDGYYWIRGRVD-DVVNVSGHRLSTSEIEASISNHE 556 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKE-----DARERAEQASKPALTLEALTSWSKDKLA 224 V E AV+G+PDE G+ + A + K+ +A E + P L + ++ Sbjct: 557 NVSEAAVVGIPDELTGQTVVAYVSLKDGYLQNNATEGDAEHITPDNLRRELILQVRGEIG 616 Query: 223 PYKIPTRLHLWDSLPRNAMGKV 158 P+ P + L LPR GK+ Sbjct: 617 PFASPKTIILVRDLPRTRSGKI 638
>ACS2_CANGA (Q6FXI2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 82.0 bits (201), Expect = 2e-15 Identities = 63/201 (31%), Positives = 100/201 (49%), Gaps = 14/201 (6%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKSP--SLFKEYWKRPE 560 P+ GA K G+ P ++A II G E + D G L +KSP S+ + W Sbjct: 440 PMAGAIPTKPGSTTLPFFGIDACIIDPVSGVEIEGNDVEGVLAVKSPWPSMARSVWNDHV 499 Query: 559 VTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 ++++ G++ TGD D DGY+ I GR + D++ V G++LS EIEA L+ H+ Sbjct: 500 RYVDTYMKPYPGYYFTGDGAGRDHDGYYWIRGRVD-DVVNVSGHRLSTAEIEACLVNHEN 558 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKE-----DARERAEQASKPALTLEALTSWSKDKLAP 221 + E AV+G+ DE G+ + A + KE DA E + P+ L + ++ P Sbjct: 559 ISETAVVGINDELTGQAVIAFVSLKEGYLQNDAPEGDAEHITPSNLRRELILQVRGEIGP 618 Query: 220 YKIPTRLHLWDSLPRNAMGKV 158 + P + L LP+ GK+ Sbjct: 619 FASPKCIILVRDLPKTRSGKI 639
>TYCC_BREPA (O30409) Tyrocidine synthetase 3 (Tyrocidine synthetase III)| [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Ty Length = 6486 Score = 82.0 bits (201), Expect = 2e-15 Identities = 58/185 (31%), Positives = 90/185 (48%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID------GG 530 +GKP+ V ++ GV GELCI L + YW+R E+T SF+D G Sbjct: 1812 IGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWQREELTKASFVDNPFEPGGT 1871 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD V DG+ LGR + + K+ G+++ EIEA LL+H+ V V+ D Sbjct: 1872 MYRTGDMVRYLPDGHIEYLGRIDHQV-KIRGHRIELGEIEATLLQHEAVKAVVVMARQDG 1930 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + A +V ++D + AE + + TL A Y +P+ + LP +A Sbjct: 1931 KGQNSLYAYVVAEQDI-QTAELRTYLSATLPA-----------YMVPSAFVFLEQLPLSA 1978 Query: 169 MGKVN 155 GKV+ Sbjct: 1979 NGKVD 1983 Score = 81.3 bits (199), Expect = 3e-15 Identities = 60/187 (32%), Positives = 91/187 (48%), Gaps = 8/187 (4%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 T+G+PL V+ I+ + GV GELCI L + Y +PE+TAE F+ F Sbjct: 5970 TIGRPLANVQVYIVDEQHHLQPIGVVGELCIGGAGLARGYLNKPELTAEKFVANPFRPGE 6029 Query: 526 --FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 +KTGD V DG +GR + + KV GY++ EIE+ +L + + + V+ D Sbjct: 6030 RMYKTGDLVKWRTDGTIEYIGRADEQV-KVRGYRIEIGEIESAVLAYQGIDQAVVVARDD 6088 Query: 352 EA-YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 +A G +CA V + A+++ L S +L Y IP+ D LP Sbjct: 6089 DATAGSYLCAYFV------------AATAVSVSGLRSHLAKELPAYMIPSYFVELDQLPL 6136 Query: 175 NAMGKVN 155 +A GKV+ Sbjct: 6137 SANGKVD 6143 Score = 75.9 bits (185), Expect = 1e-13 Identities = 61/188 (32%), Positives = 90/188 (47%), Gaps = 10/188 (5%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP+ A I+ + GV GELC+ + + Y +PE+TAE F+ F Sbjct: 3885 IGKPIANSTAYIVDGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFVPNPFAPGET 3944 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + K+ GY++ EIE VL + V E AV+ + +E Sbjct: 3945 MYRTGDLARWLPDGTIEYLGRIDQQV-KIRGYRIELGEIETVLSQQAQVKE-AVVAVIEE 4002 Query: 349 AYGE-VICAIIVPKE--DARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 A G+ +CA VP++ DA E E SK +L Y +P + LP Sbjct: 4003 ANGQKALCAYFVPEQAVDAAELREAMSK--------------QLPGYMVPAYYVQMEKLP 4048 Query: 178 RNAMGKVN 155 A GKV+ Sbjct: 4049 LTANGKVD 4056 Score = 67.4 bits (163), Expect = 4e-11 Identities = 59/193 (30%), Positives = 86/193 (44%), Gaps = 9/193 (4%) Frame = -2 Query: 706 ARKEGTV--GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID 536 A + GTV GKPLP + ++ GV GELCI + + Y RPE+T E F+ Sbjct: 4921 AIRSGTVPIGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVP 4980 Query: 535 GGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 F ++TGD DG LGR + + K+ G ++ EIE L + D + E Sbjct: 4981 NPFAPGERLYRTGDLAKWRADGNVEFLGRNDHQV-KIRGVRIELGEIETQLRKLDGITEA 5039 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHL 194 V+ D + +CA +V A + + A A L+ +L IP Sbjct: 5040 VVVAREDRGQEKELCAYVV----ADHKLDTAELRANLLK--------ELPQAMIPAYFVT 5087 Query: 193 WDSLPRNAMGKVN 155 D+LP A GKV+ Sbjct: 5088 LDALPLTANGKVD 5100 Score = 64.7 bits (156), Expect = 3e-10 Identities = 52/186 (27%), Positives = 76/186 (40%), Gaps = 7/186 (3%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 T+G+P+ I+ GV GE+CI L + YW +P +T E F+ F Sbjct: 2849 TIGRPIANTSLYIVNQYHQLQPIGVVGEICIGGRGLARGYWNKPALTEEKFVSHPFAAGE 2908 Query: 526 --FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 +KTGD DG +GR + + KV GY++ EIE+ LL + + V+ D Sbjct: 2909 RMYKTGDLGKWLPDGTIEYIGRIDEQV-KVRGYRIEIGEIESALLAAEKLTAAVVVVYED 2967 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 + + A E L + L S +L Y IP D LP Sbjct: 2968 QLGQSALAAYFTADEQ------------LDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLT 3015 Query: 172 AMGKVN 155 GKV+ Sbjct: 3016 PNGKVD 3021 Score = 63.2 bits (152), Expect = 8e-10 Identities = 49/160 (30%), Positives = 73/160 (45%), Gaps = 6/160 (3%) Frame = -2 Query: 619 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 458 +GE+ I + K Y+ RPE+T E FID F ++TGD DG GR + Sbjct: 799 LGEMYIAGDGVAKGYFNRPELTKEKFIDNPFRPGTKMYRTGDLAKWLPDGNMEYAGRMDY 858 Query: 457 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 278 + K+ G+++ EIE L +H+ V E V+ DE+ V+ A +V S Sbjct: 859 QV-KIRGHRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVLYAYLV------------S 905 Query: 277 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 + LT+ L + L Y IP+ +P A GKV Sbjct: 906 ERELTVAELREFLGRTLPSYMIPSFFIRLAEIPLTANGKV 945
>BACA_BACLI (O68006) Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-depe Length = 5255 Score = 81.6 bits (200), Expect = 2e-15 Identities = 59/197 (29%), Positives = 90/197 (45%), Gaps = 7/197 (3%) Frame = -2 Query: 724 SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAE 548 S P+ + + +GKP+ V+ I+ D G GELCI L + Y RPE+T E Sbjct: 2414 SFPIDKSHQNIPIGKPIDNVKVYILNKDLQLCPLGASGELCIAGEGLARGYVNRPELTRE 2473 Query: 547 SFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 FI F ++TGD + DG LGR + + K+ GY++ EIE LL+++ Sbjct: 2474 KFIGNPFVPGERMYRTGDLAKMLPDGNIQFLGRVDQQV-KIRGYRIEPGEIENRLLKYEK 2532 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+ D + +CA + K++ E + ++ K L Y IP Sbjct: 2533 IEEAAVIAREDGDHDPYLCAYVTVKKEVEP------------EKIRAFLKKSLPDYMIPQ 2580 Query: 205 RLHLWDSLPRNAMGKVN 155 D LP GKV+ Sbjct: 2581 YFVQLDGLPLTVNGKVD 2597 Score = 79.7 bits (195), Expect = 8e-15 Identities = 57/185 (30%), Positives = 85/185 (45%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G+PL I+ + G+ GELCI + + Y RPE+TAE F+D F Sbjct: 3467 IGRPLLNTSIYIVDKELRPLPVGIAGELCIAGEGVARGYVNRPELTAEKFVDHPFEPGKK 3526 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +KTGD DG LGR + + K+ GY++ E+E LL H+ + E AV+ D+ Sbjct: 3527 MYKTGDLAMWLPDGQIEFLGRADHQV-KIRGYRIELGEVEQQLLTHEKIKEAAVIAGKDQ 3585 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 +CA I AS L + + + ++ Y IP+ D LPR Sbjct: 3586 NGNSYLCAYI------------ASDKELPAADVRQFLEREMPDYMIPSYFVKLDRLPRTP 3633 Query: 169 MGKVN 155 GKV+ Sbjct: 3634 SGKVD 3638 Score = 74.7 bits (182), Expect = 3e-13 Identities = 59/185 (31%), Positives = 81/185 (43%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G PL I+ + G GV GELCI L K Y R E+TAE FI F Sbjct: 4976 IGSPLANTSVLIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGER 5035 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +KTGD DG +GR + + K+ G+++ EIE+ L H+ + E V DE Sbjct: 5036 LYKTGDLAKWLPDGNIEFIGRIDHQV-KIRGFRIELGEIESRLEMHEDINETIVTVREDE 5094 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 ICA I + ++L+ L + +KL Y IP D LP Sbjct: 5095 ESRPYICAYITANRE------------ISLDELKGFLGEKLPDYMIPAYFVKMDKLPLTK 5142 Query: 169 MGKVN 155 GKV+ Sbjct: 5143 NGKVD 5147 Score = 74.7 bits (182), Expect = 3e-13 Identities = 59/185 (31%), Positives = 81/185 (43%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G PL I+ + G GV GELCI L K Y R E+TAE FI F Sbjct: 349 IGSPLANTSVLIMDEAGKLVPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGER 408 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +KTGD DG +GR + + K+ G+++ EIE+ L H+ + E V DE Sbjct: 409 LYKTGDLAKWLPDGNIEFIGRIDHQV-KIRGFRIELGEIESRLEMHEDINETIVTVREDE 467 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 ICA I + ++L+ L + +KL Y IP D LP Sbjct: 468 ESRPYICAYITANRE------------ISLDELKGFLGEKLPEYMIPAYFVKLDKLPLTK 515 Query: 169 MGKVN 155 GKV+ Sbjct: 516 NGKVD 520 Score = 56.6 bits (135), Expect = 8e-08 Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 10/187 (5%) Frame = -2 Query: 685 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID----GGFFK 521 GKPL + ++ + GV GEL I + Y E T SFI G +K Sbjct: 1389 GKPLANQKIYVLNQNKQLCPVGVEGELYIGGAGVASGYIHDQEKTEHSFIQHQELGYIYK 1448 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL--PD-- 353 TGD + EDGY LGR ++ + K+ GY++ EIE L+ H + + +V+ PD Sbjct: 1449 TGDYGVLKEDGYVEFLGRKDSQV-KIRGYRVEMGEIENTLVSHQEITKASVIDYTSPDGI 1507 Query: 352 -EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 Y V+ + + D +E ++ L Y IP + + +P Sbjct: 1508 KNLYAFVVAENAISQLDVKEFLQKT-----------------LPDYMIPAKFVQIEEIPL 1550 Query: 175 NAMGKVN 155 GKV+ Sbjct: 1551 TVNGKVD 1557
>4CL1_ARATH (Q42524) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (At4CL1)| (4-coumaroyl-CoA synthase 1) Length = 561 Score = 81.6 bits (200), Expect = 2e-15 Identities = 49/183 (26%), Positives = 93/183 (50%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ D ++ ++ GE+CI+ + K Y P TAE+ G+ Sbjct: 377 KSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGW 436 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +++K G++++ E+EA+L+ H + + AV+ + +EA Sbjct: 437 LHTGDIGLIDDDDELFIVDRLK-ELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEA 495 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V +D+ L+ + + + ++ YK ++ +S+P+ Sbjct: 496 AGEVPVAFVVKSKDSE----------LSEDDVKQFVSKQVVFYKRINKVFFTESIPKAPS 545 Query: 166 GKV 158 GK+ Sbjct: 546 GKI 548
>ACSA_STRCO (Q9X928) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 81.3 bits (199), Expect = 3e-15 Identities = 55/195 (28%), Positives = 94/195 (48%), Gaps = 8/195 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVT 554 PL G K G+ +PLP + A ++ D+ E +G G + + PS+ + W + Sbjct: 426 PLPGVTHAKPGSAQRPLPGISATVVDDEANEVPNGGGGYLVLTEPWPSMLRTIWGDDQRF 485 Query: 553 AESF---IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 +++ +G +F GD D+DG +LGR + D+M V G+ +S E+E+ L+ H +V Sbjct: 486 IDTYWSRFEGKYF-AGDGAKKDDDGDIWLLGRVD-DVMLVSGHNISTTEVESALVSHPSV 543 Query: 382 LECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTR 203 E AV+G DE G+ I A ++ + E + ++ L + L P P R Sbjct: 544 AEAAVVGATDETTGQAIVAFVILRGTTAESEDLVAE-------LRNHVGATLGPIAKPKR 596 Query: 202 LHLWDSLPRNAMGKV 158 + LP+ GK+ Sbjct: 597 ILPVSELPKTRSGKI 611
>4CL2_ORYSA (Q42982) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 569 Score = 81.3 bits (199), Expect = 3e-15 Identities = 50/183 (27%), Positives = 95/183 (51%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G+ G + E K++ D + ++ GE+CI+ P + K Y PE TA + G+ Sbjct: 386 KSGSCGTVVRNAELKVVDPDTGFSLGRNLPGEICIRGPQIMKGYLNDPEATAATIDVEGW 445 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD VD+D I+ R +++K G+++ E+E++L+ H ++ + AV+ D+ Sbjct: 446 LHTGDIGYVDDDDEVFIVDRVK-ELIKFKGFQVPPAELESLLIAHPSIADAAVVPQKDDV 504 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V +A+ +T E++ + ++ YK ++H ++P++A Sbjct: 505 AGEVPVAFVV----------RAADSDITEESIKEFISKQVVFYKRLHKVHFIHAIPKSAS 554 Query: 166 GKV 158 GK+ Sbjct: 555 GKI 557
>LGRD_BREPA (Q70LM4) Linear gramicidin synthetase subunit D [Includes:| ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-Leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-d Length = 5085 Score = 81.3 bits (199), Expect = 3e-15 Identities = 55/187 (29%), Positives = 87/187 (46%), Gaps = 8/187 (4%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 T+G+P P + ++ + GV GEL I L + YW RPE+TAE F+ F Sbjct: 3351 TIGRPFPNTKLYVLDQNRKPVPVGVPGELYIGGECLARGYWNRPELTAERFVANPFGQPG 3410 Query: 526 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 ++TGD V DG LGR + D +K+ GY++ EI L +H + E VL Sbjct: 3411 ERLYRTGDLVRYLPDGNVDYLGRFD-DQVKIRGYRIELGEIAEALRQHAAIREAVVLARE 3469 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 + + A + A++ L+++ + W K+KL Y +P ++P Sbjct: 3470 VRPGDKRLAAYLT----------SAAEQELSVDEIKQWLKEKLPDYMVPASYTWLPAIPL 3519 Query: 175 NAMGKVN 155 N GKV+ Sbjct: 3520 NVNGKVD 3526 Score = 79.7 bits (195), Expect = 8e-15 Identities = 57/186 (30%), Positives = 90/186 (48%), Gaps = 8/186 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G+P+ ++ + GV GEL I L + YW RPE+TAESFI F Sbjct: 768 IGRPIANATVYVLDANLNPVPVGVPGELYIGGKGLARGYWNRPELTAESFIPHPFGTAGE 827 Query: 526 --FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 ++TGD V +DG LGR + + K+ GY++ EIE + +H V E V+ + Sbjct: 828 RLYRTGDLVRYRQDGNLEFLGRIDHQV-KIRGYRIELGEIENAIRQHPAVQEAVVIAREE 886 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 +A + + A +V A +A PA E + + K+ L Y +P + D++P Sbjct: 887 KAGDKRLAAYLV-------AAGKAQPPA---EEIALFLKETLPEYMVPAGVVWLDAIPLT 936 Query: 172 AMGKVN 155 GKV+ Sbjct: 937 VNGKVD 942 Score = 73.2 bits (178), Expect = 8e-13 Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 8/193 (4%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG 533 GA E +G+P ++ GV GEL + L + Y RP++TAE F+ Sbjct: 4400 GATNEPLIGRPQFNTHVFVLDSHRKPVPVGVPGELYLSGSGLARGYLHRPDLTAERFVQN 4459 Query: 532 GF-------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 F ++TGD V DG +GR + + K+ GY++ EIE+VL V E Sbjct: 4460 PFREPGARMYRTGDLVRYLPDGNLQFVGRVDYQV-KIRGYRIELGEIESVLNRFPGVKEV 4518 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHL 194 +L D + + A IV + D + + L + DKL Y IP + Sbjct: 4519 VLLAREDREGDKCLVAYIVFEADCTSK----------IHDLNHFLADKLPAYMIPQHYMI 4568 Query: 193 WDSLPRNAMGKVN 155 DSLP+ GK++ Sbjct: 4569 LDSLPKTPNGKLD 4581 Score = 56.6 bits (135), Expect = 8e-08 Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 9/188 (4%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 T+G+P+ V+ I+ GV GEL I SL + Y RP++T E F+ F Sbjct: 1827 TIGRPIDNVQVYILDAHRQPVPVGVSGELYIGGSSLARGYLNRPDLTQERFVAHPFTEKA 1886 Query: 526 ----FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 ++TGD V DG +GR + D + G+++ E+E ++ V E V Sbjct: 1887 GARLYRTGDLVRSLPDGSIEFIGRAD-DQTSIRGFRVELGEVETAIVALPAVKEAVVTVC 1945 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 D+ + + A +V +E A AL + K+ L Y +P LP Sbjct: 1946 TDKQGTKRLAAYLVLEEGA----------ALATGDIRKALKETLPDYMVPAFFTQLAYLP 1995 Query: 178 RNAMGKVN 155 GKV+ Sbjct: 1996 LTPNGKVD 2003
>ACS2_ZYGBA (Q96VC7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 675 Score = 81.3 bits (199), Expect = 3e-15 Identities = 59/188 (31%), Positives = 95/188 (50%), Gaps = 7/188 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMD-DGTETK--DGVGELCIKS--PSLFKEYWKRPEVTAESFID 536 K G+ P V+A II G E + D G L +KS PS+ + W+ ++++ Sbjct: 447 KPGSATVPFFGVDACIIDPVTGIELQGNDVEGVLAVKSSWPSMARSVWQNHHRYVDTYLK 506 Query: 535 G--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 G++ TGD D DGY+ I GR + D++ V G++LS EIEA L HD V E AV+G Sbjct: 507 PYPGYYFTGDGAGRDHDGYYWIRGRVD-DVVNVSGHRLSTAEIEASLTNHDNVSESAVVG 565 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 + DE G+ + A + K+ + + ++S L + ++ P+ P + L L Sbjct: 566 IADELTGQSVIAFVSLKDGS---SRESSAVVAMRRELVLQVRGEIGPFAAPKCVILVKDL 622 Query: 181 PRNAMGKV 158 P+ GK+ Sbjct: 623 PKTRSGKI 630
>ACSA_STRAW (Q82EL5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 80.9 bits (198), Expect = 4e-15 Identities = 56/196 (28%), Positives = 94/196 (47%), Gaps = 8/196 (4%) Frame = -2 Query: 721 NPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEV 557 +PL G K G+ +PLP + A ++ D+ E +G G + + PS+ + W + Sbjct: 425 SPLPGVTETKPGSAQRPLPGISATVVDDEAREVPNGGGGYLVLTEPWPSMLRTIWGDDQR 484 Query: 556 TAESF---IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 +++ +G +F GD DEDG +LGR + D+M V G+ +S E+E+ L+ H + Sbjct: 485 FLDTYWSRFEGKYF-AGDGAKKDEDGDIWLLGRVD-DVMLVSGHNISTTEVESALVSHPS 542 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 V E AV+G DE G+ I A ++ + A + + L + L P P Sbjct: 543 VAEAAVVGAADETTGQAIVAFVILRGTANAEDDN------LVADLRNHVGTTLGPIAKPK 596 Query: 205 RLHLWDSLPRNAMGKV 158 R+ LP+ GK+ Sbjct: 597 RILPVAELPKTRSGKI 612
>ACSA_EMENI (P16928) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 80.9 bits (198), Expect = 4e-15 Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDG---VGELCIKSP--SLFKEYWKRPE 560 PL G K G+ P +E II E G G L K P S+ + W + Sbjct: 442 PLAGVTPTKPGSASLPFFGIEPAIIDPVSGEEISGNDVEGVLAFKQPWPSMARTVWGAHK 501 Query: 559 VTAESFID--GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 ++++ G++ TGD D +GY+ I GR + D++ V G++LS EIEA L+EH Sbjct: 502 RYMDTYLQVYKGYYFTGDGAGRDHEGYYWIRGRVD-DVVNVSGHRLSTAEIEAALIEHPM 560 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 V E AV+G+ DE G+ + A + KE E +Q K L L+ + + P+ P Sbjct: 561 VAEAAVVGIADELTGQAVNAFVSLKE-GNETNDQVRKD-LILQV-----RKSIGPFAAPK 613 Query: 205 RLHLWDSLPRNAMGKV 158 + + D LP+ GK+ Sbjct: 614 AVFVVDDLPKTRSGKI 629
>ACS1_ASHGO (Q758X0) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 694 Score = 80.5 bits (197), Expect = 5e-15 Identities = 51/162 (31%), Positives = 81/162 (50%), Gaps = 9/162 (5%) Frame = -2 Query: 616 GELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIM 449 G L +K P S + W + +++++ G++ GD D G+ ILGR + D++ Sbjct: 502 GVLAVKQPWPSFTRTIWNNHDRYLDTYLNPYKGYYFAGDGAARDSQGFIWILGRVD-DVV 560 Query: 448 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE-----DARERAEQ 284 V G++LS E+EA +++ V ECAV+G DE G+ I A +V K+ A ER Q Sbjct: 561 NVSGHRLSTAEVEAAIIQESMVAECAVVGFADELTGQAIAAFVVLKQKSSWNTASERELQ 620 Query: 283 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 K L L + + P+ P + L D LP+ GK+ Sbjct: 621 EIKKHLILSV-----RRDIGPFAAPKLIVLVDDLPKTRSGKI 657
>4CL1_TOBAC (O24145) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 547 Score = 80.5 bits (197), Expect = 5e-15 Identities = 51/183 (27%), Positives = 92/183 (50%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDG--TETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ D + ++ GE+CI+ + K Y PE T + G+ Sbjct: 361 KSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDPEATTRTIDKEGW 420 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +DED I+ R +++K G++++ EIEA+LL H + + AV+ + DE Sbjct: 421 LHTGDIGFIDEDDELFIVDRLK-ELIKYKGFQVAPAEIEALLLNHPNISDAAVVPMKDEQ 479 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V +++ A+T + + + ++ YK R+ +++P++ Sbjct: 480 AGEVPVAFVV----------RSNGSAITEDEVKDFISKQVIFYKRVKRVFFVETVPKSPS 529 Query: 166 GKV 158 GK+ Sbjct: 530 GKI 532
>ACSA_LEPIN (Q8EYG2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 80.5 bits (197), Expect = 5e-15 Identities = 56/189 (29%), Positives = 95/189 (50%), Gaps = 7/189 (3%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG---VGELCIKSP--SLFKEYWKRPEVTAESFI 539 +K G+ P V+ ++ +DG E D G LCIK P S+ + + P+ E++ Sbjct: 441 QKPGSATLPFFGVQPVLVDNDGKEITDKGEVSGNLCIKGPWPSMMRGVYGDPKRFFETYF 500 Query: 538 DG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 G++ TGD D+DGYF I GR + D++ V G+++ + E+E+ L+E+ +V E AV+ Sbjct: 501 SQFKGYYFTGDGARRDKDGYFWITGRVD-DVINVSGHRIGSAEVESALVENKSVAEAAVV 559 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G P + G+ I A + KE + L E +++ K + P +H Sbjct: 560 GFPHDIKGQGIYAYVTVKEGV------TTNDVLKKELISTVEK-MIGKIARPDVIHWAPG 612 Query: 184 LPRNAMGKV 158 LP+ GK+ Sbjct: 613 LPKTRSGKI 621
>ACSA_LEPIC (Q72LY9) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 80.5 bits (197), Expect = 5e-15 Identities = 56/189 (29%), Positives = 95/189 (50%), Gaps = 7/189 (3%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG---VGELCIKSP--SLFKEYWKRPEVTAESFI 539 +K G+ P V+ ++ +DG E D G LCIK P S+ + + P+ E++ Sbjct: 441 QKPGSATLPFFGVQPVLVDNDGKEITDKGEVSGNLCIKGPWPSMMRGVYGDPKRFFETYF 500 Query: 538 DG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 G++ TGD D+DGYF I GR + D++ V G+++ + E+E+ L+E+ +V E AV+ Sbjct: 501 SQFKGYYFTGDGARRDKDGYFWITGRVD-DVINVSGHRIGSAEVESALVENKSVAEAAVV 559 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G P + G+ I A + KE + L E +++ K + P +H Sbjct: 560 GFPHDIKGQGIYAYVTVKEGV------TTNDVLKKELISTVEK-MIGKIARPDVIHWAPG 612 Query: 184 LPRNAMGKV 158 LP+ GK+ Sbjct: 613 LPKTRSGKI 621
>ACSA_CHLTE (Q8KBY0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 659 Score = 80.1 bits (196), Expect = 6e-15 Identities = 62/201 (30%), Positives = 96/201 (47%), Gaps = 13/201 (6%) Frame = -2 Query: 721 NPLHGAR--KEGTVGKPLPRVEAKIIMDDGT--ETKDGVGELCIKSP--SLFKEYW---K 569 +P+ GA K GT +PLP + ++ DGT +G G L +K P S+ + + + Sbjct: 436 SPMPGATPTKPGTATRPLPGIMVDVVRKDGTPCNANEG-GYLVVKRPWPSMLRTIYGDNE 494 Query: 568 RPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 R E T S G +F TGD D+DGY I+GR + D++ V G++L E+E+ L+ H+ Sbjct: 495 RYEKTYWSEFPGMYF-TGDGARKDDDGYIWIMGRVD-DVVNVSGHRLGTSEVESALVSHE 552 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKE----DARERAEQASKPALTLEALTSWSKDKLAP 221 V E AV+ PDE G + A + K+ DA+ R A + A+ Sbjct: 553 AVAEAAVVSRPDEIKGNALVAFVTLKDGYEGDAKLRDSLGKHVAKEIGAIAK-------- 604 Query: 220 YKIPTRLHLWDSLPRNAMGKV 158 P + LP+ GK+ Sbjct: 605 ---PDEIRWAKGLPKTRSGKI 622
>ACSA_YERPE (Q8D1G8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 79.7 bits (195), Expect = 8e-15 Identities = 64/197 (32%), Positives = 100/197 (50%), Gaps = 10/197 (5%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCI------KSPSLFKEYWK 569 PL GA K G+ +P V+ ++ D+ ++GV G L I ++ +LF ++ + Sbjct: 425 PLPGATELKAGSATRPFFGVQPALV-DNLGNPQEGVAEGNLVITDSWPGQARTLFGDH-E 482 Query: 568 RPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 R E T S G +F +GD DEDGY+ I GR + D++ V G++L EIE+ L+ H Sbjct: 483 RFEQTYFSTFKGMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEIESALVAHP 540 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIP 209 + E AV+G+P G+ I A I + P L E + +W + ++ P P Sbjct: 541 KIAEAAVVGVPHNIKGQAIYAYITLNHG------EEPTPELYTE-VRNWVRKEIGPLATP 593 Query: 208 TRLHLWDSLPRNAMGKV 158 LH DSLP+ GK+ Sbjct: 594 DILHWTDSLPKTRSGKI 610
>ACSA_ECOLI (P27550) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 79.7 bits (195), Expect = 8e-15 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWKR 566 PL GA K G+ +P V+ ++ ++G + G L I ++ +LF ++ +R Sbjct: 425 PLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITDSWPGQARTLFGDH-ER 483 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S +F +GD DEDGY+ I GR + D++ V G++L EIE+ L+ H Sbjct: 484 FEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEIESALVAHPK 541 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+G+P G+ I A + E+ S P L E + +W + ++ P P Sbjct: 542 IAEAAVVGIPHNIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRKEIGPLATPD 594 Query: 205 RLHLWDSLPRNAMGKV 158 LH DSLP+ GK+ Sbjct: 595 VLHWTDSLPKTRSGKI 610
>ACSA_ECOL6 (Q8FAY8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 79.7 bits (195), Expect = 8e-15 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWKR 566 PL GA K G+ +P V+ ++ ++G + G L I ++ +LF ++ +R Sbjct: 425 PLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITDSWPGQARTLFGDH-ER 483 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S +F +GD DEDGY+ I GR + D++ V G++L EIE+ L+ H Sbjct: 484 FEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEIESALVAHPK 541 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+G+P G+ I A + E+ S P L E + +W + ++ P P Sbjct: 542 IAEAAVVGIPHNIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRKEIGPLATPD 594 Query: 205 RLHLWDSLPRNAMGKV 158 LH DSLP+ GK+ Sbjct: 595 VLHWTDSLPKTRSGKI 610
>MENE_ENTFA (Q838K1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 485 Score = 79.7 bits (195), Expect = 8e-15 Identities = 55/184 (29%), Positives = 90/184 (48%), Gaps = 1/184 (0%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGG 530 A K G+ G+PL ++ KI+ + G E + VGE+ +K P++ Y + + E + G Sbjct: 301 ALKIGSAGQPLKDMQIKIVDELGQEQPEKQVGEILLKGPNVVSGYLNQRQ--PEKWTADG 358 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +FKTGD +D Y ++ R + I+ GG + E+E VL + AV+G PD Sbjct: 359 WFKTGDMGYLDAQSYLYLVSRLSELIIS-GGENIYPTEVEQVLQAITGIKAAAVVGEPDA 417 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 +G V A ++ ++ +TL + KLA YK P R++ S P+ A Sbjct: 418 QWGAVPVAYVISDQE------------ITLAQIQDQCSRKLAKYKRPKRIYFCHSFPQTA 465 Query: 169 MGKV 158 GK+ Sbjct: 466 SGKI 469
>ACSA_SYNEL (Q8DKH2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 79.3 bits (194), Expect = 1e-14 Identities = 58/194 (29%), Positives = 95/194 (48%), Gaps = 13/194 (6%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGE---LCIKSP--SLFKEYWKRPEVTAESFI- 539 K G+ KP P + A ++ +G GV E L I+ P + + + P+ ++ Sbjct: 440 KPGSASKPFPGILADVVDLEGNPV--GVNEGGYLVIRHPWPGMMRTVYGDPDRFRRTYWE 497 Query: 538 -----DGGFFK-TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLE 377 DG +F GD DEDGYF ++GR + D++ V G++L +EIE+ L+ H V E Sbjct: 498 HIPPRDGQYFYFAGDGARRDEDGYFWVMGRVD-DVINVSGHRLGTMEIESALVSHPAVAE 556 Query: 376 CAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTL-EALTSWSKDKLAPYKIPTRL 200 AV+G PDE GE I A ++ E ++ P+ L + L +++ P + Sbjct: 557 AAVVGKPDEVKGEEIVAFVI--------LEGSATPSDALQQELKQHVVNEIGALARPAEI 608 Query: 199 HLWDSLPRNAMGKV 158 D+LP+ GK+ Sbjct: 609 RFTDALPKTRSGKI 622
>4CL_PINTA (P41636) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 537 Score = 79.3 bits (194), Expect = 1e-14 Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G+ G + + KI+ + E+ + GE+CI+ P + K Y PE TA + + G+ Sbjct: 356 KSGSCGTVVRNAQIKILDTETGESLPHNQAGEICIRGPEIMKGYINDPESTAATIDEEGW 415 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +I+K G++++ E+EA+L+ H ++ + AV+ E Sbjct: 416 LHTGDVEYIDDDEEIFIVDRVK-EIIKYKGFQVAPAELEALLVAHPSIADAAVVPQKHEE 474 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V + E +EQ K + + + YK R++ D++P++ Sbjct: 475 AGEVPVAFVV---KSSEISEQEIKEFVAKQVIF---------YKKIHRVYFVDAIPKSPS 522 Query: 166 GKV 158 GK+ Sbjct: 523 GKI 525
>ACSA_VIBPA (Q87KU7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 79.0 bits (193), Expect = 1e-14 Identities = 58/196 (29%), Positives = 93/196 (47%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LCIKSPSLFKEYW---KR 566 PL GA K G+ +P V+ ++ + G +D V E + P + + +R Sbjct: 425 PLPGATDLKPGSATRPFFGVQPALVDNMGNILEDTVAEGNLVILDSWPGQMRTVYGDHER 484 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S G +F T D DEDGY+ I GR + D++ V G+++ EIE+ L+ H Sbjct: 485 FEQTYFSTFKGMYF-TSDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAHHK 542 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E A++G+P + G+ I A I + AE + + W + ++ P P Sbjct: 543 IAEAAIVGIPHDIKGQAIYAYITLNDGEFPSAELHKE-------VKDWVRKEIGPIATPD 595 Query: 205 RLHLWDSLPRNAMGKV 158 LH DSLP+ GK+ Sbjct: 596 VLHWTDSLPKTRSGKI 611
>ACSA_COPCI (O13440) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 79.0 bits (193), Expect = 1e-14 Identities = 45/125 (36%), Positives = 70/125 (56%) Frame = -2 Query: 532 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 G+F TGD DEDGY I GR + D++ V G++LS EIE+ L+ H V E AV+G D Sbjct: 502 GYFYTGDGAARDEDGYIWIKGRVD-DVINVSGHRLSTAEIESALITHTGVAETAVIGTAD 560 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 E G+ + A + K + + AE ++ L+ E + K + P+ P R+++ LP+ Sbjct: 561 ELTGQAVYAFVTLKPEFKFDAE--NEAGLSKELILQVRK-IIGPFAAPKRIYIVSDLPKT 617 Query: 172 AMGKV 158 GK+ Sbjct: 618 RSGKI 622
>ACSA_DEIRA (Q9RRL7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 78.6 bits (192), Expect = 2e-14 Identities = 56/187 (29%), Positives = 93/187 (49%), Gaps = 6/187 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF---I 539 K G+ G P+ VE ++ DG E D G L + PS+ + + E +S+ I Sbjct: 439 KPGSAGLPMFGVEPALMTRDGEEIGDDDGGLLVIKRPWPSMLRTVYGDDERYRKSYWGEI 498 Query: 538 DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 +F GD D DGY+ I+GR + D++ V G++L +EIE+ L+ H V E AV+G Sbjct: 499 PHVYF-AGDGARRDHDGYYTIVGRVD-DVLNVSGHRLGTMEIESALVAHPDVSEAAVVGR 556 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 PD GE + A ++ ++ + PA AL + ++ P +++ D+LP Sbjct: 557 PDPVKGESVVAYVLLQDG------HTADPA----ALRAHVSSEIGALARPDAIYIADALP 606 Query: 178 RNAMGKV 158 + GK+ Sbjct: 607 KTRSGKI 613
>ACSA_NEUCR (P16929) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 667 Score = 78.6 bits (192), Expect = 2e-14 Identities = 55/196 (28%), Positives = 94/196 (47%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKII---MDDGTETKDGVGELCIKSP--SLFKEYWKRPE 560 PL G K G+ P +E ++ + D G L K P S+ + W + Sbjct: 440 PLAGVTPTKPGSASFPFFGIEPALVDPVTGEEIHGNDVEGVLAFKQPWPSMARTVWGAHK 499 Query: 559 VTAESFID--GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E+++ G++ TGD D +G++ I GR + D++ V G++LS EIEA L+EH + Sbjct: 500 RYMETYLHVYKGYYFTGDGAARDHEGFYWIRGRVD-DVVNVSGHRLSTAEIEAALIEHHS 558 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+G+ DE G+ + A + KE + A + L+ S + P+ P Sbjct: 559 IAEAAVVGVADELTGQAVNAFVAVKEGT--QINDALRKEFVLQVRRS-----IGPFAAPK 611 Query: 205 RLHLWDSLPRNAMGKV 158 +++ LP+ GK+ Sbjct: 612 AIYIVPDLPKTRSGKI 627
>4CL2_TOBAC (O24146) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 542 Score = 78.6 bits (192), Expect = 2e-14 Identities = 49/183 (26%), Positives = 91/183 (49%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ + ++ GE+CI+ + K Y PE TA + G+ Sbjct: 356 KSGACGTVVRNAEMKIVDPKTGNSLPRNQSGEICIRGDQIMKGYLNDPEATARTIDKEGW 415 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +++K G++++ E+EA+LL H + + AV+ + DE Sbjct: 416 LYTGDIGYIDDDDELFIVDRLK-ELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQ 474 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V +++ +T + + + ++ YK R+ D++P++ Sbjct: 475 AGEVPVAFVV----------RSNGSTITEDEVKDFISKQVIFYKRIKRVFFVDAIPKSPS 524 Query: 166 GKV 158 GK+ Sbjct: 525 GKI 527
>ACSA_CAUCR (Q9A2I0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 78.6 bits (192), Expect = 2e-14 Identities = 61/195 (31%), Positives = 96/195 (49%), Gaps = 8/195 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIKS--PSLFKEYWKRPEV 557 PL GA K G+ KPLP V+ +++ +G + DG G L I P + + + Sbjct: 424 PLPGATALKPGSASKPLPGVKPQLVDAEG-KFLDGATEGNLVITDSWPGQMRTVYGDHQR 482 Query: 556 TAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 E++ G + TGD D DGY+ I GR + D++ V G++L EIE+ L+ H+TV Sbjct: 483 FFETYFSTYPGKYFTGDGCRRDADGYYWITGRVD-DVINVSGHRLGTAEIESALVAHETV 541 Query: 382 LECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTR 203 E AV+G P + G+ + A + K A A A + L L W + ++ P+ P Sbjct: 542 AEAAVVGYPHDIKGQGVYAYVTLK--AGIEATDALRKDLVL-----WVRHEIGPFAAPDV 594 Query: 202 LHLWDSLPRNAMGKV 158 + LP+ GK+ Sbjct: 595 IQWAPGLPKTRSGKI 609
>ACSA_SALTY (Q8ZKF6) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 78.2 bits (191), Expect = 2e-14 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWKR 566 PL GA K G+ +P V+ ++ ++G + G L I ++ +LF ++ +R Sbjct: 425 PLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDH-ER 483 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S +F +GD DEDGY+ I GR + D++ V G++L EIE+ L+ H Sbjct: 484 FEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEIESALVAHPK 541 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+G+P G+ I A + E+ S P L E + +W + ++ P P Sbjct: 542 IAEAAVVGIPHAIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRKEIGPLATPD 594 Query: 205 RLHLWDSLPRNAMGKV 158 LH DSLP+ GK+ Sbjct: 595 VLHWTDSLPKTRSGKI 610
>ACSA_SALTI (Q8Z1R0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 78.2 bits (191), Expect = 2e-14 Identities = 62/196 (31%), Positives = 99/196 (50%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWKR 566 PL GA K G+ +P V+ ++ ++G + G L I ++ +LF ++ +R Sbjct: 425 PLPGAIELKAGSATRPFFGVQPALVDNEGHPQEGATEGNLVITDSWPGQARTLFGDH-ER 483 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S +F +GD DEDGY+ I GR + D++ V G++L EIE+ L+ H Sbjct: 484 FEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEIESALVAHPK 541 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+G+P G+ I A + E+ S P L E + +W + ++ P P Sbjct: 542 IAEAAVVGIPHAIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRKEIGPLATPD 594 Query: 205 RLHLWDSLPRNAMGKV 158 LH DSLP+ GK+ Sbjct: 595 VLHWTDSLPKTRSGKI 610
>ACS1_CANAL (O94049) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 675 Score = 77.8 bits (190), Expect = 3e-14 Identities = 59/190 (31%), Positives = 93/190 (48%), Gaps = 9/190 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKII-MDDGTETKDG--VGELCIKS--PSLFKEYWKRPEVTAESFID 536 K G+ P V+ KI+ G E D G L IKS PS+ + + ++++ Sbjct: 453 KPGSASLPFFGVDPKILDPTTGEELPDNDVEGVLAIKSAWPSITRGIYNDYNRFIDTYLA 512 Query: 535 --GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 ++ +GD D DG++ ILGR + D++ V G++LS EIEA L+EH V E AV+G Sbjct: 513 PYANYYFSGDGAARDRDGFYWILGRVD-DVVNVSGHRLSTAEIEAALIEHPIVGESAVVG 571 Query: 361 LPDEAYGEVICAIIVPKED--ARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWD 188 DE G+ + A + K+D E E K + + ++ P+ P + L D Sbjct: 572 YADELTGQAVAAYVSLKKDKAVGEDVENIKKEMILT------VRKEIGPFAAPKMILLVD 625 Query: 187 SLPRNAMGKV 158 LP+ GK+ Sbjct: 626 DLPKTRSGKI 635
>ACSA_VIBVY (Q7MGU3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 77.8 bits (190), Expect = 3e-14 Identities = 56/196 (28%), Positives = 92/196 (46%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LCIKSPSLFKEYW---KR 566 PL GA K G+ +P V+ ++ + G +D E + P + + +R Sbjct: 425 PLPGATALKPGSATRPFFGVQPALVDNMGNVIEDQAAEGNLVILDSWPGQMRTVYGDHER 484 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S G +F TGD DEDGY+ I GR + D++ V G+++ EIE+ L+ H Sbjct: 485 FEQTYFSTFKGMYF-TGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAHPK 542 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E A++G+P + G+ I A + AE + + W + ++ P P Sbjct: 543 IAEAAIVGIPHDIKGQAIYAYVTLNAGEYPTAELHKE-------VKDWVRKEIGPIATPD 595 Query: 205 RLHLWDSLPRNAMGKV 158 LH D+LP+ GK+ Sbjct: 596 VLHWTDALPKTRSGKI 611
>ACSA_VIBVU (Q8DCZ9) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 77.8 bits (190), Expect = 3e-14 Identities = 56/196 (28%), Positives = 92/196 (46%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LCIKSPSLFKEYW---KR 566 PL GA K G+ +P V+ ++ + G +D E + P + + +R Sbjct: 425 PLPGATALKPGSATRPFFGVQPALVDNMGNVIEDQAAEGNLVILDSWPGQMRTVYGDHER 484 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S G +F TGD DEDGY+ I GR + D++ V G+++ EIE+ L+ H Sbjct: 485 FEQTYFSTFKGMYF-TGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAHPK 542 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E A++G+P + G+ I A + AE + + W + ++ P P Sbjct: 543 IAEAAIVGIPHDIKGQAIYAYVTLNAGEYPTAELHKE-------VKDWVRKEIGPIATPD 595 Query: 205 RLHLWDSLPRNAMGKV 158 LH D+LP+ GK+ Sbjct: 596 VLHWTDALPKTRSGKI 611
>4CL2_PETCR (P14913) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 77.8 bits (190), Expect = 3e-14 Identities = 51/183 (27%), Positives = 91/183 (49%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ + + ++ GE+CI+ + K Y PE T + + G+ Sbjct: 357 KSGACGTVVRNAEMKIVDPETNASLPRNQRGEICIRGDQIMKGYLNDPESTRTTIDEEGW 416 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +I+K G++++ E+EA+LL H T+ + AV+ + DE Sbjct: 417 LHTGDIGFIDDDDELFIVDRLK-EIIKYKGFQVAPAELEALLLTHPTISDAAVVPMIDEK 475 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V + + T E + + ++ YK R+ D++P++ Sbjct: 476 AGEVPVAFVV----------RTNGFTTTEEEIKQFVSKQVVFYKRIFRVFFVDAIPKSPS 525 Query: 166 GKV 158 GK+ Sbjct: 526 GKI 528
>4CL1_PETCR (P14912) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 77.8 bits (190), Expect = 3e-14 Identities = 51/183 (27%), Positives = 91/183 (49%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ + + ++ GE+CI+ + K Y PE T + + G+ Sbjct: 357 KSGACGTVVRNAEMKIVDPETNASLPRNQRGEICIRGDQIMKGYLNDPESTRTTIDEEGW 416 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +I+K G++++ E+EA+LL H T+ + AV+ + DE Sbjct: 417 LHTGDIGFIDDDDELFIVDRLK-EIIKYKGFQVAPAELEALLLTHPTISDAAVVPMIDEK 475 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V + + T E + + ++ YK R+ D++P++ Sbjct: 476 AGEVPVAFVV----------RTNGFTTTEEEIKQFVSKQVVFYKRIFRVFFVDAIPKSPS 525 Query: 166 GKV 158 GK+ Sbjct: 526 GKI 528
>4CL_VANPL (O24540) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 553 Score = 77.8 bits (190), Expect = 3e-14 Identities = 51/183 (27%), Positives = 90/183 (49%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ + + ++ GE+CI+ + K Y PE TA + G+ Sbjct: 365 KSGACGTVVRNAEMKIVDPETGSSLPRNHPGEICIRGDQIMKGYLNDPEATARTIDKEGW 424 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +++K G++++ E+EA+LL H + + AV+ + DEA Sbjct: 425 LHTGDIGYIDDDDELFIVDRLK-ELIKYKGFQVAPAELEALLLTHPCISDAAVVPMKDEA 483 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V K + E K ++ + + YK R+ +++P+ Sbjct: 484 AGEVPVAFVV-KSNGHNITEDEIKQFISKQVIF---------YKRINRVFFVEAIPKAPS 533 Query: 166 GKV 158 GK+ Sbjct: 534 GKI 536
>4CL4_ARATH (Q9LU36) 4-coumarate--CoA ligase 4 (EC 6.2.1.12) (4CL 4) (At4CL4)| (4-coumaroyl-CoA synthase 4) (4-coumarate CoA ligase isoform 5) Length = 570 Score = 77.4 bits (189), Expect = 4e-14 Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 5/186 (2%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET-----KDGVGELCIKSPSLFKEYWKRPEVTAESFID 536 K G G + E K++ TET ++ GE+C++ L K Y PE TA + Sbjct: 384 KSGACGTVIRNAEMKVV---DTETGISLPRNKSGEICVRGHQLMKGYLNDPEATARTIDK 440 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD VD+D I+ R +++K GY+++ E+EA+L+ H ++ + AV+ + Sbjct: 441 DGWLHTGDIGFVDDDDEIFIVDRLK-ELIKFKGYQVAPAELEALLISHPSIDDAAVVAMK 499 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 DE EV A + AR + Q LT + + S+ ++ YK + + +P+ Sbjct: 500 DEVADEVPVAFV-----ARSQGSQ-----LTEDDVKSYVNKQVVHYKRIKMVFFIEVIPK 549 Query: 175 NAMGKV 158 GK+ Sbjct: 550 AVSGKI 555
>ALKK_PSEOL (Q00594) Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)| (Medium-chain acyl-CoA synthetase) Length = 546 Score = 77.4 bits (189), Expect = 4e-14 Identities = 54/179 (30%), Positives = 88/179 (49%), Gaps = 3/179 (1%) Frame = -2 Query: 685 GKPLPRVEAKIIMDDGTET-KDG--VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 515 G+P VE KI+ D+G +DG G L + + K+Y+ S + G+F TG Sbjct: 360 GRPPYGVELKIVNDEGIRLPEDGRSKGNLMARGHWVIKDYFHSDP---GSTLSDGWFSTG 416 Query: 514 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 335 D T+D DG+ I R DI+K GG +S +E+E++ + H +++ AV+ E + E Sbjct: 417 DVATIDSDGFMTICDRAK-DIIKSGGEWISTVELESIAIAHPHIVDAAVIAARHEKWDER 475 Query: 334 ICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 I V ++ LT + ++ DK+A ++IP + LPRN GK+ Sbjct: 476 PLLIAVKSPNSE----------LTSGEVCNYFADKVARWQIPDAAIFVEELPRNGTGKI 524
>ACSA_ECO57 (Q8X5T5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 77.4 bits (189), Expect = 4e-14 Identities = 61/196 (31%), Positives = 98/196 (50%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWKR 566 PL GA K G+ +P V+ ++ ++G + G L I ++ +LF ++ +R Sbjct: 425 PLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITDSWPGQARTLFGDH-ER 483 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S +F +GD DED Y+ I GR + D++ V G++L EIE+ L+ H Sbjct: 484 FEQTYFSTFKNMYF-SGDGARRDEDSYYWITGRVD-DVLNVSGHRLGTAEIESALVAHPK 541 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+G+P G+ I A + E+ S P L E + +W + ++ P P Sbjct: 542 IAEAAVVGIPHNIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRKEIGPLATPD 594 Query: 205 RLHLWDSLPRNAMGKV 158 LH DSLP+ GK+ Sbjct: 595 VLHWTDSLPKTRSGKI 610
>Y3568_PSEAE (P28812) Hypothetical protein PA3568| Length = 628 Score = 77.0 bits (188), Expect = 5e-14 Identities = 50/187 (26%), Positives = 94/187 (50%), Gaps = 6/187 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTE---TKDGVGELCIK-SPSLFKEYWKRPEVTAESFIDG 533 + G+ + +P +++ D+G + G + + P + W ++++ Sbjct: 410 RAGSTNRAVPGYHVQVLDDEGRPLGANRQGAIVIALPLPPGCAQTLWGDHPRYLQAYLGN 469 Query: 532 --GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL 359 G++ TGD +DEDG+ I+GRT+ D++ V G++LS E+E + +H V ECAV+G+ Sbjct: 470 YPGYYHTGDGGYLDEDGFVYIMGRTD-DVINVSGHRLSTGEMEERVAQHQAVAECAVIGV 528 Query: 358 PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 DE G V ++V K+DA AEQ + + L ++++ R+ + LP Sbjct: 529 RDELKGHVPLGLVVLKDDAGIAAEQLQRELVAL------VREQIGALACFQRVVVVKRLP 582 Query: 178 RNAMGKV 158 + GK+ Sbjct: 583 KTRSGKI 589
>LUCI_PHOPE (Q27757) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 545 Score = 76.3 bits (186), Expect = 9e-14 Identities = 44/132 (33%), Positives = 71/132 (53%), Gaps = 4/132 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETK----DGVGELCIKSPSLFKEYWKRPEVTAESFIDG 533 + G+ GK +P K++ D T K + GEL K + K Y+ E T Sbjct: 357 RPGSTGKIVPFHAVKVV--DPTTGKILGPNETGELYFKGDMIMKSYYNNEEATKAIINKD 414 Query: 532 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 G+ ++GD D DG+F I+ R + ++K GY+++ EIE +LL+H +++ V G+PD Sbjct: 415 GWLRSGDIAYYDNDGHFYIVDRLKS-LIKYKGYQVAPAEIEGILLQHPYIVDAGVTGIPD 473 Query: 352 EAYGEVICAIIV 317 EA GE+ A +V Sbjct: 474 EAAGELPAAGVV 485
>4CL2_SOLTU (P31685) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 545 Score = 76.3 bits (186), Expect = 9e-14 Identities = 48/183 (26%), Positives = 92/183 (50%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDG--TETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ D + ++ GE+CI+ + K Y PE TA + G+ Sbjct: 359 KSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDPEATARTIEKEGW 418 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +++K G++++ E+EA+L+ H + + AV+ + DE Sbjct: 419 LHTGDIGFIDDDDELFIVDRLK-ELIKYKGFQVAPAELEALLINHPDISDAAVVPMIDEQ 477 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V +++ +T + + + ++ YK R+ +++P++ Sbjct: 478 AGEVPVAFVV----------RSNGSTITEDEVKDFISKQVIFYKRIKRVFFVETVPKSPS 527 Query: 166 GKV 158 GK+ Sbjct: 528 GKI 530
>4CL1_SOLTU (P31684) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 545 Score = 76.3 bits (186), Expect = 9e-14 Identities = 48/183 (26%), Positives = 92/183 (50%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDG--TETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ D + ++ GE+CI+ + K Y PE TA + G+ Sbjct: 359 KSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDPEATARTIEKEGW 418 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +++K G++++ E+EA+L+ H + + AV+ + DE Sbjct: 419 LHTGDIGFIDDDDELFIVDRLK-ELIKYKGFQVAPAELEALLINHPDISDAAVVPMIDEQ 477 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V +++ +T + + + ++ YK R+ +++P++ Sbjct: 478 AGEVPVAFVV----------RSNGSTITEDEVKDFISKQVIFYKRIKRVFFVETVPKSPS 527 Query: 166 GKV 158 GK+ Sbjct: 528 GKI 530
>MENE_STAEQ (Q5HNB2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 76.3 bits (186), Expect = 9e-14 Identities = 52/178 (29%), Positives = 86/178 (48%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVGKP VE KI + G GEL IK ++ Y P+ ++F + G+F+TGD Sbjct: 297 TVGKPSENVEVKIKNPNAY----GHGELLIKGENVMNGYLY-PKYLKDTFDNDGYFQTGD 351 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D++GY II R D++ GG + +IE + + + + + +G+ D+ +G+V Sbjct: 352 IAEIDDEGYVIIYDR-RKDLIISGGENIYPYQIETIAKDFEGIEDAVCVGISDDTWGQVP 410 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V +D + L ++ LA YKIP + + SLP + GK+ Sbjct: 411 ILYYVTNQDINQ------------TELIEHFENHLARYKIPKKYYQVKSLPYTSTGKL 456
>4CL1_SOYBN (P31686) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment) Length = 293 Score = 75.9 bits (185), Expect = 1e-13 Identities = 49/183 (26%), Positives = 88/183 (48%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ + + ++ GE+CI+ + K Y E T + G+ Sbjct: 106 KPGACGTVVRNAEMKIVDPETGHSLPRNQSGEICIRGDQIMKGYLNDGEATERTIDKDGW 165 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +++K G++++ E+EA+LL H + + AV+ + DEA Sbjct: 166 LHTGDIGYIDDDDELFIVDRLK-ELIKYKGFQVAPAELEALLLTHPKISDAAVVPMKDEA 224 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V + E K ++ + + YK R+ D++P++ Sbjct: 225 AGEVPVAFVVISNGYTDTTEDEIKQFISKQVVF---------YKRINRVFFIDAIPKSPS 275 Query: 166 GKV 158 GK+ Sbjct: 276 GKI 278
>ACSA_BRAJA (Q89WV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 648 Score = 75.9 bits (185), Expect = 1e-13 Identities = 59/201 (29%), Positives = 94/201 (46%), Gaps = 14/201 (6%) Frame = -2 Query: 718 PLHGARK--EGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKS--PSLFKEYW---KRP 563 PL GA K G+ +P V +I+ DG + + G LC+ P + + + R Sbjct: 422 PLPGATKLKPGSATQPFFGVVPEIVDADGKVLEGETTGNLCLTRAWPGMMRTVYGDHARF 481 Query: 562 EVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 E T S G +F TGD D DGY+ I GR + D++ V G+++ E+E+ L+ H+ V Sbjct: 482 EQTYFSTYKGKYF-TGDGCRRDADGYYWITGRVD-DVINVSGHRMGTAEVESALVAHEKV 539 Query: 382 LECAVLGLPDEAYGEVICAIIV------PKEDARERAEQASKPALTLEALTSWSKDKLAP 221 E AV+G P + G+ I A + P ED R+ L +W + ++ P Sbjct: 540 SEAAVVGFPHDIKGQGIYAYVTLMAGVQPTEDLRKE-------------LVTWVRKEIGP 586 Query: 220 YKIPTRLHLWDSLPRNAMGKV 158 P ++ LP+ GK+ Sbjct: 587 IASPDQIQFAPGLPKTRSGKI 607
>ACSA_CAMJE (Q9PMD2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 657 Score = 75.1 bits (183), Expect = 2e-13 Identities = 59/198 (29%), Positives = 97/198 (48%), Gaps = 11/198 (5%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRPEVT 554 PL GA K G PLP + A++I ++G + +G G LCI P S+ + W E Sbjct: 425 PLPGATPLKPGCATLPLPGIFAEVIDEEGNKKDEGEDGLLCITKPWPSMIRGIWGNDERY 484 Query: 553 AESFI-----DG-GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEH 392 ES+ DG + +GD D++GY I GRT+ D++ V G+++ EIE+ + +H Sbjct: 485 IESYFSQAKKDGKAVYFSGDGAFYDKNGYITITGRTD-DVVNVAGHRIGTAEIESAIAKH 543 Query: 391 DTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKI 212 +V E AV+ + D GE + A +V + A + TL+ L + ++ P Sbjct: 544 PSVAESAVVSILDTIKGESLFAFVVLSPASSCDLGGAIE---TLKELNDILRVEIGPIAK 600 Query: 211 PTRLHLWDSLPRNAMGKV 158 ++ LP+ GK+ Sbjct: 601 IEKILYTPGLPKTRSGKI 618
>MENE_STAES (Q8CS21) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 74.7 bits (182), Expect = 3e-13 Identities = 51/178 (28%), Positives = 86/178 (48%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVGK VE KI + G GEL IK ++ Y P+ ++F + G+F+TGD Sbjct: 297 TVGKTSENVEVKIKNPNAY----GHGELLIKGENVMNGYLY-PKYLKDTFDNDGYFQTGD 351 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D++GY II R D++ GG + +IE + + + + + +G+ D+ +G+V Sbjct: 352 IAEIDDEGYVIIYDR-RKDLIISGGENIYPYQIETIAKDFEGIEDAVCVGISDDTWGQVP 410 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V +D + L ++ LA YKIP + + +SLP + GK+ Sbjct: 411 ILYYVTNQDINQ------------NELIEHFENHLARYKIPKKYYQVESLPYTSTGKL 456
>4CL2_ARATH (Q9S725) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (At4Cl2)| (4-coumaroyl-CoA synthase 2) Length = 556 Score = 74.7 bits (182), Expect = 3e-13 Identities = 46/183 (25%), Positives = 91/183 (49%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KI+ D ++ ++ GE+CI+ + K Y P TA + G+ Sbjct: 370 KSGACGTVVRNAEMKILDPDTGDSLPRNKPGEICIRGNQIMKGYLNDPLATASTIDKDGW 429 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +D+D I+ R +++K G++++ E+E++L+ H + + AV+ + +E Sbjct: 430 LHTGDVGFIDDDDELFIVDRLK-ELIKYKGFQVAPAELESLLIGHPEINDVAVVAMKEED 488 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 GEV A +V +D+ ++ + + + ++ YK ++ DS+P+ Sbjct: 489 AGEVPVAFVVRSKDSN----------ISEDEIKQFVSKQVVFYKRINKVFFTDSIPKAPS 538 Query: 166 GKV 158 GK+ Sbjct: 539 GKI 541
>BAIB_EUBSP (P19409) Bile acid-coenzyme A ligase (EC 6.-.-.-)| Length = 520 Score = 74.7 bits (182), Expect = 3e-13 Identities = 57/185 (30%), Positives = 90/185 (48%), Gaps = 5/185 (2%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTETKD-GVGELCIKSPS--LFKEY--WKRPEVTAESFIDGG 530 G++G+P+ + I ++G E +GE+ + +P+ L EY W+ EV +GG Sbjct: 341 GSIGRPVGDSKVSIRDENGKEVAPFEIGEIYMTAPASYLVTEYINWEPLEVK-----EGG 395 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 F GD VDE GY R +D++ GG + A E+E LL + +L+ V+G+PDE Sbjct: 396 FRSVGDIGYVDEQGYLYFSDR-RSDMLVSGGENVFATEVETALLRYKDILDAVVVGIPDE 454 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 G + A+I E +E + E L ++ + L PYKIP S+ R Sbjct: 455 DLGRRLHAVI---ETGKE---------IPAEELKTFLRKYLTPYKIPKTFEFVRSIRRGD 502 Query: 169 MGKVN 155 GK + Sbjct: 503 NGKAD 507
>4CL3_ARATH (Q9S777) 4-coumarate--CoA ligase 3 (EC 6.2.1.12) (4CL 3) (At4CL3)| (4-coumaroyl-CoA synthase 3) Length = 561 Score = 74.7 bits (182), Expect = 3e-13 Identities = 50/186 (26%), Positives = 93/186 (50%), Gaps = 5/186 (2%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVG-----ELCIKSPSLFKEYWKRPEVTAESFID 536 K G+ G + E K++ ET+ +G E+CI+ + KEY PE T+ + + Sbjct: 380 KSGSCGTVVRNAELKVVH---LETRLSLGYNQPGEICIRGQQIMKEYLNDPEATSATIDE 436 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 G+ TGD VDED I+ R +++K G+++ E+E++L+ H ++ + AV+ Sbjct: 437 EGWLHTGDIGYVDEDDEIFIVDRLK-EVIKFKGFQVPPAELESLLINHHSIADAAVVPQN 495 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 DE GEV A +V +++ +T E + + ++ YK ++ S+P+ Sbjct: 496 DEVAGEVPVAFVV----------RSNGNDITEEDVKEYVAKQVVFYKRLHKVFFVASIPK 545 Query: 175 NAMGKV 158 + GK+ Sbjct: 546 SPSGKI 551
>ACSA2_PSEAE (Q9HV66) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 645 Score = 74.7 bits (182), Expect = 3e-13 Identities = 58/194 (29%), Positives = 93/194 (47%), Gaps = 7/194 (3%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKD-GVGELCIKS--PSLFKEYWKRPEVT 554 PL GA K G+ +P V+ ++ + G E G G L IK+ PS + + + Sbjct: 422 PLPGATALKPGSATRPFFGVQPVLLDEKGKEIDGAGSGVLAIKASWPSQIRSVYGDHQRM 481 Query: 553 AESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVL 380 +++ G++ +GD DEDGY+ I GR + D++ V G+++ E+E+ L+ HD V Sbjct: 482 IDTYFKPYPGYYFSGDGARRDEDGYYWITGRVD-DVINVSGHRIGTAEVESALVLHDAVA 540 Query: 379 ECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL 200 E AV+G P + G+ I A + A AL E L K+ + + P L Sbjct: 541 EAAVVGCPHDVKGQAIYAFVT------LMAGSQPSEALQQELLALVGKE-IGSFAKPDHL 593 Query: 199 HLWDSLPRNAMGKV 158 SLP+ GK+ Sbjct: 594 QWAPSLPKTRSGKI 607
>SRFAA_BACSU (P27206) Surfactin synthetase subunit 1| Length = 3588 Score = 74.3 bits (181), Expect = 4e-13 Identities = 57/187 (30%), Positives = 83/187 (44%), Gaps = 9/187 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP+ E I+ G G+ GELC+ L K Y+ RPE+T E F+ F Sbjct: 1818 IGKPVSNTEVYILDRTGHVQPAGIAGELCVTGEGLVKGYYNRPELTEEKFVPHPFTSGER 1877 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +KTGD +G +GR + + K+ G + EIE L HD V E VL + Sbjct: 1878 MYKTGDLARWLPNGTIEFIGRIDHQV-KIRGQAIELGEIEHQLQTHDRVQESVVLAVDQG 1936 Query: 349 AYGEVICAIIVPKED--ARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 A +++CA V + D ++E E A+K L Y +P D LP Sbjct: 1937 AGDKLLCAYYVGEGDISSQEMREHAAK--------------DLPAYMVPAVFIQMDELPL 1982 Query: 175 NAMGKVN 155 GK++ Sbjct: 1983 TGNGKID 1989 Score = 65.9 bits (159), Expect = 1e-10 Identities = 57/185 (30%), Positives = 81/185 (43%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GK L I+ G +GV GEL I + + Y PE+T E F+ F Sbjct: 779 IGKALGNNRLYILDQKGRLQPEGVAGELYIAGDGVGRGYLHLPELTEEKFLQDPFVPGDR 838 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD V DG LGR + D +KV GY++ EIEAV+ + V + VL PDE Sbjct: 839 MYRTGDVVRWLPDGTIEYLGRED-DQVKVRGYRIELGEIEAVIQQAPDVAKAVVLARPDE 897 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 +CA +V K + PA L + +L Y +P +P Sbjct: 898 QGNLEVCAYVVQKPGSE------FAPA----GLREHAARQLPDYMVPAYFTEVTEIPLTP 947 Query: 169 MGKVN 155 GKV+ Sbjct: 948 SGKVD 952 Score = 63.9 bits (154), Expect = 5e-10 Identities = 55/197 (27%), Positives = 85/197 (43%), Gaps = 7/197 (3%) Frame = -2 Query: 724 SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAE 548 S +H ++G+ + I+ + +GV GELC+ L + Y R + TA+ Sbjct: 2840 SAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAK 2899 Query: 547 SFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 F+ F ++TGD V G I GR + + KV GY++ EIE L + Sbjct: 2900 RFVADPFVPGERMYRTGDLVKWTGGGIEYI-GRIDQQV-KVRGYRIELSEIEVQLAQLSE 2957 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 V + AV + D+ I A + P+ + +EAL S K+ L Y IP Sbjct: 2958 VQDAAVTAVKDKGGNTAIAAYVTPE-------------SADIEALKSALKETLPDYMIPA 3004 Query: 205 RLHLWDSLPRNAMGKVN 155 + LP A GKV+ Sbjct: 3005 FWVTLNELPVTANGKVD 3021
>MENE_STAAW (Q8NVZ4) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 73.9 bits (180), Expect = 5e-13 Identities = 50/178 (28%), Positives = 81/178 (45%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVG P V+ KI K+G GEL IK ++ Y ++T + G+F TGD Sbjct: 326 TVGMPSANVDVKI----KNPNKEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGD 379 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D +GY +I R D++ GG + +IE V + + + +G PD+ +G+V Sbjct: 380 IAEIDHEGYVMIYDR-RKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVP 438 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V + D ++ L ++ LA YK+P D+LP + GK+ Sbjct: 439 KLYFVSESD------------ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAU (Q53634) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 73.9 bits (180), Expect = 5e-13 Identities = 50/178 (28%), Positives = 81/178 (45%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVG P V+ KI K+G GEL IK ++ Y ++T + G+F TGD Sbjct: 326 TVGMPSANVDVKI----KNPNKEGHGELMIKGANVMNVYLYPTDLTGT--FENGYFNTGD 379 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D +GY +I R D++ GG + +IE V + + + +G PD+ +G+V Sbjct: 380 IAEIDHEGYVMIYDR-RKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVP 438 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V + D ++ L ++ LA YK+P D+LP + GK+ Sbjct: 439 KLYFVSESD------------ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAS (Q6G8D6) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 73.9 bits (180), Expect = 5e-13 Identities = 50/178 (28%), Positives = 81/178 (45%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVG P V+ KI K+G GEL IK ++ Y ++T + G+F TGD Sbjct: 326 TVGMPSANVDVKI----KNPNKEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGD 379 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D +GY +I R D++ GG + +IE V + + + +G PD+ +G+V Sbjct: 380 IAEIDHEGYVMIYDR-RKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVP 438 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V + D ++ L ++ LA YK+P D+LP + GK+ Sbjct: 439 KLYFVSESD------------ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAC (Q5HEY2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 73.9 bits (180), Expect = 5e-13 Identities = 50/178 (28%), Positives = 81/178 (45%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVG P V+ KI K+G GEL IK ++ Y ++T + G+F TGD Sbjct: 326 TVGMPSANVDVKI----KNPNKEGHGELMIKGANVMNVYLYPTDLTGT--FENGYFNTGD 379 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D +GY +I R D++ GG + +IE V + + + +G PD+ +G+V Sbjct: 380 IAEIDHEGYVMIYDR-RKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVP 438 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V + D ++ L ++ LA YK+P D+LP + GK+ Sbjct: 439 KLYFVSESD------------ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>ACSA_RHOCA (O68040) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 73.6 bits (179), Expect = 6e-13 Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 16/203 (7%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV----GELCIKS--PSLFKEYWKRP 563 PL GA K G+ P V+ +++D T + G G LCI P + W Sbjct: 430 PLPGATPTKPGSATNPFFGVKP-VVLDPQTAVRIGEVECEGVLCISDSWPGQMRTVWGDH 488 Query: 562 EVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 + E++ G++ TGD D+DGY+ I GR + D++ V G+++ E+E+ L+ H Sbjct: 489 DRFQETYFGQYRGYYFTGDGCRRDKDGYYWITGRVD-DVINVSGHRMGTAEVESALVAHP 547 Query: 388 TVLECAVLGLPDEAYGEVICAIIV------PKEDARERAEQASKPALTLEALTSWSKDKL 227 V E AV+G P + G+ I A + P ED R + L W + ++ Sbjct: 548 QVAEAAVVGYPHDIKGQGIYAYVTLMNGIEPSEDLR-------------KDLVKWVRTEI 594 Query: 226 APYKIPTRLHLWDSLPRNAMGKV 158 P P + LP+ GK+ Sbjct: 595 GPIASPDLIQWAPGLPKTRSGKI 617
>MENE_STAAN (P63526) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 73.6 bits (179), Expect = 6e-13 Identities = 50/178 (28%), Positives = 81/178 (45%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVG P V+ KI K+G GEL IK ++ Y ++T + G+F TGD Sbjct: 326 TVGMPSANVDVKI----KNPNKEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGD 379 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D +GY +I R D++ GG + +IE V + + + +G PD+ +G+V Sbjct: 380 IAEIDHEGYVMIYDR-RKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVP 438 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V + D ++ L ++ LA YK+P D+LP + GK+ Sbjct: 439 KLYFVSESD------------ISKAQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAM (P63525) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 73.6 bits (179), Expect = 6e-13 Identities = 50/178 (28%), Positives = 81/178 (45%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVG P V+ KI K+G GEL IK ++ Y ++T + G+F TGD Sbjct: 326 TVGMPSANVDVKI----KNPNKEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGD 379 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D +GY +I R D++ GG + +IE V + + + +G PD+ +G+V Sbjct: 380 IAEIDHEGYVMIYDR-RKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVP 438 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V + D ++ L ++ LA YK+P D+LP + GK+ Sbjct: 439 KLYFVSESD------------ISKAQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKL 484
>ACSA_DROME (Q9VP61) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) Length = 670 Score = 73.6 bits (179), Expect = 6e-13 Identities = 56/194 (28%), Positives = 91/194 (46%), Gaps = 7/194 (3%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKSP--SLFKEYWKRPEVT 554 PL GA K G+ P V+ ++ + G E K +G G L P + + + E Sbjct: 446 PLPGATPMKPGSASFPFFGVKPTLLDECGIEIKGEGEGYLVFSQPWPGMMRTLYNNHERF 505 Query: 553 AESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVL 380 +++ G++ TGD D DGY I GR + D++ V G+ +S E+E+VL EH V Sbjct: 506 EDTYFSKFPGYYCTGDGARRDADGYLWITGRVD-DMLNVSGHLMSTAEVESVLTEHPRVA 564 Query: 379 ECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL 200 E AV+ P GE + I P E+ E +Q + L ++++ P+ +P + Sbjct: 565 ESAVVSRPHPVKGECLYCFITPNEN--EVFDQK-----LISDLKKMVRERIGPFAMPDVI 617 Query: 199 HLWDSLPRNAMGKV 158 LP+ GK+ Sbjct: 618 QNAPGLPKTRSGKI 631
>LGRA_BREPA (Q70LM7) Linear gramicidin synthetase subunit A [Includes:| ATP-dependent valine/leucine adenylase (Val/LeuA) (Valine/leucine activase); ATP-dependent glycine adenylase (GlyA) (Glycine activase)] Length = 2273 Score = 72.8 bits (177), Expect = 1e-12 Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESF----IDGG-- 530 +GKPLP II G GV GELCI SL + Y P +T E F ++ G Sbjct: 1534 IGKPLPNYRMYIINRHGQLQPIGVPGELCIAGASLARGYLNNPALTEEKFTPHPLEKGER 1593 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD EDG LGR + + K+ GY++ EI + L++ +T+ + V+ D+ Sbjct: 1594 IYRTGDLARYREDGNIEYLGRMDHQV-KIRGYRIELDEIRSKLIQEETIQDAVVVARNDQ 1652 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 +CA ++ +++ T+ L + +L Y IP L P A Sbjct: 1653 NGQAYLCAYLLSEQE------------WTVGQLRELLRRELPEYMIPAHFVLLKQFPLTA 1700 Query: 169 MGKVN 155 GK++ Sbjct: 1701 NGKLD 1705 Score = 60.8 bits (146), Expect = 4e-09 Identities = 54/186 (29%), Positives = 83/186 (44%), Gaps = 8/186 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI-----DGGF 527 +GKP+ R I+ + GV GEL I L + Y RPE+TAE FI Sbjct: 503 IGKPIDRTRILILDEALALQPIGVAGELFIVGEGLGRGYLNRPELTAEKFIVHPQTGERM 562 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 ++TGD DG LGR + +++K+ GY++ EIE L+ H ++E + ++A Sbjct: 563 YRTGDRARFLPDGNIEFLGRLD-NLVKIRGYRIEPGEIEPFLMNH-PLIELTTVLAKEQA 620 Query: 346 YGE--VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 G ++ + P+E + L W + L Y IPT + P Sbjct: 621 DGRKYLVGYYVAPEE-------------IPHGELREWLGNDLPDYMIPTYFVHMKAFPLT 667 Query: 172 AMGKVN 155 A GKV+ Sbjct: 668 ANGKVD 673
>MENE_STAAR (Q6GFR0) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 72.8 bits (177), Expect = 1e-12 Identities = 50/178 (28%), Positives = 81/178 (45%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 TVG P V+ KI K G GEL IK ++ Y ++T + G+F TGD Sbjct: 326 TVGMPSANVDVKI----KNPNKKGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGD 379 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 +D +GY +I R D++ GG + +IE V + +++ +G PD+ +G+V Sbjct: 380 IAEIDHEGYVMIYDR-RKDLIISGGENIYPYQIETVAKQFPGIIDAVCVGHPDDTWGQVP 438 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 V S+ ++ L ++ LA YK+P D+LP + GK+ Sbjct: 439 KLYFV------------SESNISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>ACSA_VIBCH (Q9KV59) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 72.0 bits (175), Expect = 2e-12 Identities = 58/196 (29%), Positives = 92/196 (46%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGVGE----LCIKSPSLFKEYW---KR 566 PL GA K G+ +P V+ ++ D+ E +G E L P + + R Sbjct: 425 PLPGATALKPGSATRPFFGVQPALV-DNMGEIVEGATEGNLVLLDSWPGQMRTVYGDHDR 483 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 E T S G +F TGD DEDGY+ I GR + D++ V G+++ EIE+ L+ + Sbjct: 484 FEQTYFSTFKGMYF-TGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAFNK 541 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 + E AV+G+P + G+ I A I + AE + + W + ++ P Sbjct: 542 IAEAAVVGVPHDIKGQAIYAYITLNDGVYPSAELHKE-------VKDWVRKEIGAIATPD 594 Query: 205 RLHLWDSLPRNAMGKV 158 LH D+LP+ GK+ Sbjct: 595 VLHWTDALPKTRSGKI 610
>ACSA2_RHIME (Q92KX2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 649 Score = 72.0 bits (175), Expect = 2e-12 Identities = 55/196 (28%), Positives = 93/196 (47%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIKS--PSLFKEYWKRPEV 557 PL GA K G+ +P V+ +I+ DG + DG G LCI P + + E Sbjct: 425 PLPGATDLKPGSATRPFFGVQPQIVDSDG-KVVDGAADGNLCITDSWPGQMRTVYGDHER 483 Query: 556 TAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 +++ G + TGD DEDGY+ I GR + D++ V G++L E+E+ L+ H+ V Sbjct: 484 FIQTYFSTYKGKYFTGDGCRRDEDGYYWITGRVD-DVLNVSGHRLGTAEVESALVSHNLV 542 Query: 382 LECAVLGLPDEAYGE-VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 E AV+G P G+ + C + + + + + +AL + ++ P P Sbjct: 543 SEAAVVGYPHPIKGQGIYCYVSLMAGEVGDDELR--------QALVKHVRSEIGPIATPD 594 Query: 205 RLHLWDSLPRNAMGKV 158 ++ LP+ GK+ Sbjct: 595 KIQFAPGLPKTRSGKI 610
>ACSA_HUMAN (Q9NR19) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 72.0 bits (175), Expect = 2e-12 Identities = 57/194 (29%), Positives = 89/194 (45%), Gaps = 7/194 (3%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKSP--SLFKEYWKRPEVT 554 PL GA K G+ P V I+ + G E + + G L K P + + + E Sbjct: 477 PLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHERF 536 Query: 553 AESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVL 380 ++ G++ TGD D+DGY+ I GR + D++ V G+ LS E+E+ L+EH+ V Sbjct: 537 ETTYFKKFPGYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTAEVESALVEHEAVA 595 Query: 379 ECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL 200 E AV+G P GE + + + P LT E L ++K+ P P + Sbjct: 596 EAAVVGHPHPVKGECLYCFVTLCDG------HTFSPKLT-EELKKQIREKIGPIATPDYI 648 Query: 199 HLWDSLPRNAMGKV 158 LP+ GK+ Sbjct: 649 QNAPGLPKTRSGKI 662
>ACSA_PHYBL (Q01576) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 72.0 bits (175), Expect = 2e-12 Identities = 55/197 (27%), Positives = 92/197 (46%), Gaps = 9/197 (4%) Frame = -2 Query: 721 NPLHGARKEGTVGKPLPRVEAKIIMDDGTETKD-----GVGELCIKSP--SLFKEYWKRP 563 +PL GA LP ++ D T K+ G L I+ P S+ + + Sbjct: 438 SPLPGATPTKPGSATLPFFGIDPVLLDPTTGKELTATGQTGVLAIRKPRPSMARSVYNNH 497 Query: 562 EVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 E+++ G++ TGD D+DGY I GR + D++ V G++LS EIE+ L+ H+ Sbjct: 498 SRFVETYLKPYPGYYFTGDGALRDDDGYIWIRGRVD-DVINVSGHRLSTSEIESALVNHE 556 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIP 209 V E AV+G D+ G+ I A + K + + LTL+ + + P+ P Sbjct: 557 AVAESAVVGAHDDLTGQCIHAFVSLKPHI--QIADGLEKVLTLQV-----RKTIGPFAAP 609 Query: 208 TRLHLWDSLPRNAMGKV 158 R+++ P+ GK+ Sbjct: 610 RRIYIVSDHPKTRSGKI 626
>ACSA_RHOBA (P59872) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 671 Score = 71.6 bits (174), Expect = 2e-12 Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 7/145 (4%) Frame = -2 Query: 721 NPLHGAR--KEGTVGKPLPRVEAKIIMDDGTET-KDGVGELCIKSP--SLFKEYWKRPEV 557 +PL G K G+ +PLP V I+ + G + G+LCI P + + + E Sbjct: 452 SPLPGITPTKPGSCTRPLPGVVPSIVDELGNSVDSEHGGKLCISQPWPGMLRGIYGDEER 511 Query: 556 TAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 E + + TGD D DGY+ I+GR + D++ V G++LS +E+E+ L+ H V Sbjct: 512 FVEQYWSDVPDKYLTGDNARCDTDGYYWIMGRID-DVINVSGHRLSTIEVESALVSHPDV 570 Query: 382 LECAVLGLPDEAYGEVICAIIVPKE 308 E AV+G P + G+ I A + + Sbjct: 571 CEAAVVGRPHDLKGQAIAAFVTSND 595
>ACS2L_HUMAN (Q9NUB1) Acetyl-coenzyme A synthetase 2-like, mitochondrial| precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (Acyl-CoA synthetase short-chain family member 1) Length = 689 Score = 71.6 bits (174), Expect = 2e-12 Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 7/173 (4%) Frame = -2 Query: 655 IIMDDGTETKDGV---GELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVD 497 ++MD+ +G G LCI P + + + + +++ G++ TGD Sbjct: 479 VLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRT 538 Query: 496 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 317 E GY+ I GR + D++ + G++L EIE + +H V E AV+G P + GE A IV Sbjct: 539 EGGYYQITGRMD-DVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIV 597 Query: 316 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 K+ A + + ++ L S K+A Y +P + + LP+ GKV Sbjct: 598 VKDSAGD-------SDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKV 643
>ACSA_BRUSU (Q8FYQ3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 71.2 bits (173), Expect = 3e-12 Identities = 54/195 (27%), Positives = 91/195 (46%), Gaps = 8/195 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIKS--PSLFKEYWKRPEV 557 PL GA K G+ +P V+ ++ ++G ++GV G LCI P + + + Sbjct: 425 PLPGATDLKPGSATRPFFGVKPVLVDNEGN-VQEGVADGNLCISDSWPGQMRTVYGDHKR 483 Query: 556 TAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 E++ G + +GD DEDGY+ I GR + D++ + G++L EIE+ L+ H +V Sbjct: 484 FIETYFSTYKGMYFSGDGCRRDEDGYYWITGRVD-DVLNISGHRLGTAEIESALVSHHSV 542 Query: 382 LECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTR 203 E AV+G P G+ I + A A P + L + ++ P P + Sbjct: 543 SEAAVVGYPHPIKGQGIYCYVTLMTGA-----DAQDPDELRKELVQHVRKEIGPIATPDK 597 Query: 202 LHLWDSLPRNAMGKV 158 + LP+ GK+ Sbjct: 598 IQFAPGLPKTRSGKI 612
>ACSA_BRUME (Q8YJ48) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 71.2 bits (173), Expect = 3e-12 Identities = 54/195 (27%), Positives = 91/195 (46%), Gaps = 8/195 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCIKS--PSLFKEYWKRPEV 557 PL GA K G+ +P V+ ++ ++G ++GV G LCI P + + + Sbjct: 425 PLPGATDLKPGSATRPFFGVKPVLVDNEGN-VQEGVADGNLCISDSWPGQMRTVYGDHKR 483 Query: 556 TAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 E++ G + +GD DEDGY+ I GR + D++ + G++L EIE+ L+ H +V Sbjct: 484 FIETYFSTYKGMYFSGDGCRRDEDGYYWITGRVD-DVLNISGHRLGTAEIESALVSHHSV 542 Query: 382 LECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTR 203 E AV+G P G+ I + A A P + L + ++ P P + Sbjct: 543 SEAAVVGYPHPIKGQGIYCYVTLMTGA-----DAQDPDELRKELVQHVRKEIGPIATPDK 597 Query: 202 LHLWDSLPRNAMGKV 158 + LP+ GK+ Sbjct: 598 IQFAPGLPKTRSGKI 612
>ACSA_AGRT5 (Q8UBV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 70.9 bits (172), Expect = 4e-12 Identities = 58/198 (29%), Positives = 98/198 (49%), Gaps = 10/198 (5%) Frame = -2 Query: 721 NPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWK 569 +PL GA K G+ +P V+ +++ +G + G LCI +S S++ ++ + Sbjct: 424 SPLPGATDLKPGSATRPFFGVQPQLVDAEGNVLEGPADGNLCIIDSWPGQSRSVYGDHQR 483 Query: 568 RPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 + T S G +F TGD DEDGY+ I GR + D++ V G++L E+E+ L+ H Sbjct: 484 FVD-TYFSTYKGKYF-TGDGCRRDEDGYYWITGRVD-DVLNVSGHRLGTAEVESALVSHH 540 Query: 388 TVLECAVLGLPDEAYGE-VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKI 212 V E AV+G P G+ + C + + A Q+ AL E L ++++ P Sbjct: 541 QVSEAAVVGYPHPIKGQGIYCYVTL-------MAGQSGDYALR-EELVKHVRNEIGPVAT 592 Query: 211 PTRLHLWDSLPRNAMGKV 158 P ++ LP+ GK+ Sbjct: 593 PDKIQFAPGLPKTRSGKI 610
>4CL1_ORYSA (P17814) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 564 Score = 70.9 bits (172), Expect = 4e-12 Identities = 51/183 (27%), Positives = 84/183 (45%), Gaps = 2/183 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 K G G + E KII D ++ ++ GE+CI+ + K Y PE T + G+ Sbjct: 376 KSGACGTVVRNAELKIIDPDTGKSLGRNLPGEICIRGQQIMKGYLNNPEATKNTIDAEGW 435 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD VD+D I+ R +I+K G++++ E+EA+L+ H ++ + AV+G E Sbjct: 436 LHTGDIGYVDDDDEIFIVDRLK-EIIKYRGFQVAPAELEALLITHPSIADAAVVGKQIEP 494 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 I V K + E +E K + E + YK + D +P+ Sbjct: 495 EIGEIPVAFVAKTEGSELSEDDVKQFVAKEVIY---------YKKIREVFFVDKIPKAPS 545 Query: 166 GKV 158 GK+ Sbjct: 546 GKI 548
>SRFAB_BACSU (Q04747) Surfactin synthetase subunit 2| Length = 3587 Score = 69.7 bits (169), Expect = 9e-12 Identities = 55/189 (29%), Positives = 89/189 (47%), Gaps = 7/189 (3%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF- 527 K T+G+P+ A ++ + G G+L I L + Y RP++TAE F++ + Sbjct: 1817 KRPTIGRPIANAGALVLNEALKLVPPGASGQLYITGQGLARGYLNRPQLTAERFVENPYS 1876 Query: 526 -----FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 +KTGD V DG +GR + D +K+ GY++ EIE V+L + E VL Sbjct: 1877 PGSLMYKTGDVVRRLSDGTLAFIGRAD-DQVKIRGYRIELGEIETVMLSLSGIQEAVVLA 1935 Query: 361 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 182 + + E +CA +D E+AE + +LTL + + IP D++ Sbjct: 1936 VSEGGLQE-LCAYYTSDQDI-EKAELRYQLSLTLPS-----------HMIPAFFVQVDAI 1982 Query: 181 PRNAMGKVN 155 P A GK + Sbjct: 1983 PLTANGKTD 1991 Score = 61.6 bits (148), Expect = 2e-09 Identities = 55/197 (27%), Positives = 84/197 (42%), Gaps = 7/197 (3%) Frame = -2 Query: 724 SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAE 548 S +H ++G+ + I+ + +GV GELC+ L + Y R + TA+ Sbjct: 2839 SAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAK 2898 Query: 547 SFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 F+ F ++TGD V G I GR + + KV GY++ EIE L + Sbjct: 2899 RFVADPFVPGERMYRTGDLVKWVNGGIEYI-GRIDQQV-KVRGYRIELSEIEVQLAQLSE 2956 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 V + AV + D+ I A + P+ +EAL S K+ L Y IP Sbjct: 2957 VEDRAVTRVKDKGGNTAIAAYVTPE-------------TADIEALKSTLKETLPDYMIPA 3003 Query: 205 RLHLWDSLPRNAMGKVN 155 + LP A GKV+ Sbjct: 3004 FWVTLNELPVTANGKVD 3020 Score = 60.8 bits (146), Expect = 4e-09 Identities = 51/185 (27%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP+ A I+ + G GELC+ + + Y PE+T + F++ F Sbjct: 776 IGKPIGNSTAYIMDEQQCLQPIGAPGELCVGGIGVARGYVNLPELTEKQFLEDPFRPGER 835 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG LGR + + KV G+++ EIE L + V E AV+ ++ Sbjct: 836 IYRTGDLARWLPDGNIEFLGRIDNQV-KVRGFRIELGEIETKLNMAEHVTEAAVIIRKNK 894 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 A ICA + + + L L Y +P L DSLP Sbjct: 895 ADENEICAYFTADRE------------VAVSELRKTLSQSLPDYMVPAHLIQMDSLPLTP 942 Query: 169 MGKVN 155 GK+N Sbjct: 943 NGKIN 947
>ACSA1_PSEPK (Q88EH6) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 653 Score = 69.3 bits (168), Expect = 1e-11 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 10/198 (5%) Frame = -2 Query: 721 NPLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV--GELCI------KSPSLFKEYW 572 +PL GA K G+ +P V ++ D+ DG G L I +S SL+ ++ Sbjct: 424 SPLPGATGLKPGSATRPFFGVVPALV-DNLGNLIDGAAEGNLVILDSWPGQSRSLYGDHD 482 Query: 571 KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEH 392 + + ++F G + TGD DEDGY+ I GR + D++ V G+++ EIE+ ++ H Sbjct: 483 RFVDTYFKTF--RGMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESAMVAH 539 Query: 391 DTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKI 212 V E AV+G+P + G+ I + V E +EQ L LE L +W + ++ P Sbjct: 540 SKVAEAAVVGVPHDIKGQGI-YVYVTLNAGIEASEQ-----LRLE-LKNWVRKEIGPIAS 592 Query: 211 PTRLHLWDSLPRNAMGKV 158 P + LP+ GK+ Sbjct: 593 PDVIQWAPGLPKTRSGKI 610
>4CL2_SOYBN (P31687) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) (Clone 4CL16) Length = 562 Score = 68.9 bits (167), Expect = 1e-11 Identities = 49/184 (26%), Positives = 89/184 (48%), Gaps = 3/184 (1%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGG 530 K G+ G + E K++ D T G GE+CI+ + K Y TA + G Sbjct: 374 KSGSCGTVVRNAELKVV-DPETGRSLGYNQPGEICIRGQQIMKGYLNDEAATASTIDSEG 432 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 + TGD VD+D I+ R +++K G+++ E+E +L+ H ++ + AV+ D Sbjct: 433 WLHTGDVGYVDDDDEIFIVDRVK-ELIKYKGFQVPPAELEGLLVSHPSIADAAVVPQKDV 491 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 A GEV A +V +++ LT EA+ + ++ YK +++ ++P++ Sbjct: 492 AAGEVPVAFVV----------RSNGFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSP 541 Query: 169 MGKV 158 GK+ Sbjct: 542 SGKI 545
>PPS2_BACSU (P39846) Peptide synthetase 2| Length = 2560 Score = 68.6 bits (166), Expect = 2e-11 Identities = 51/191 (26%), Positives = 92/191 (48%), Gaps = 7/191 (3%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGG 530 A+ + +G+PL ++A ++ GV GEL I + + Y R E+TA+ F+ Sbjct: 1809 AKNKSNIGRPLSTLQAHVMDAHMNLQPTGVPGELYIGGEGVARGYLNRDELTADRFVSNP 1868 Query: 529 F------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAV 368 + ++TGD +G LGR + + KV G+++ EI+A LL++ + E AV Sbjct: 1869 YLPGDRLYRTGDLAKRLSNGELEYLGRIDEQV-KVRGHRIELGEIQAALLQYPMIKEAAV 1927 Query: 367 LGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWD 188 + DE I A +V K+ + A + + ++ K+ L + +P R+ D Sbjct: 1928 ITRADEQGQTAIYAYMVIKD----------QQAANISDIRTYLKNALPDFMLPARMIQID 1977 Query: 187 SLPRNAMGKVN 155 S+P GK++ Sbjct: 1978 SIPVTVNGKLD 1988 Score = 65.9 bits (159), Expect = 1e-10 Identities = 51/185 (27%), Positives = 83/185 (44%), Gaps = 6/185 (3%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 T+G P+ + ++ + + GELCI L + Y+K+ E+T ++F D F Sbjct: 777 TIGHPIRNTKVFVLHGNQMQPIGAAGELCISGAGLARGYYKQQELTQKAFSDHPFLEGER 836 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG +GR + D +K+ GY++ EIE VL + V E AVL Sbjct: 837 LYRTGDAGRFLPDGTIEYIGRFD-DQVKIRGYRIELREIETVLRQAPGVKEAAVLARDVS 895 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 A + + A IVP++ +L L L Y IP + +P + Sbjct: 896 AEEKELVAYIVPEK------------GNSLPDLYQHLAGTLPSYMIPASIINISQMPLTS 943 Query: 169 MGKVN 155 GK++ Sbjct: 944 SGKLD 948
>ACS2L_MOUSE (Q99NB1) Acetyl-coenzyme A synthetase 2-like, mitochondrial| precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) Length = 682 Score = 68.2 bits (165), Expect = 3e-11 Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 7/173 (4%) Frame = -2 Query: 655 IIMDDGTETKDG---VGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVD 497 ++MD+ +G G LCI P + + + + +++ G++ TGD Sbjct: 472 VLMDEKGNVLEGGDVSGALCISQAWPGMARTIYGDHQRFVDAYFRAYPGYYFTGDGAHRT 531 Query: 496 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 317 E GY+ I GR + D++ + G++L EIE + +H V E AV+G P + GE A IV Sbjct: 532 EGGYYQITGRMD-DVINISGHRLGTAEIEDAMADHPAVPETAVIGYPHDIKGEAAFAFIV 590 Query: 316 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 K++ + ++ L++ K+A Y +P ++ + LP+ GKV Sbjct: 591 LKDNISDENMVVNELKLSVAT-------KIAKYAVPDQILVVKRLPKTRSGKV 636
>ACSA_SHEON (Q8EDK3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 68.2 bits (165), Expect = 3e-11 Identities = 38/125 (30%), Positives = 60/125 (48%) Frame = -2 Query: 532 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 G + TGD DEDGY+ I GR + D++ V G++L E+E+ L+ H+ V E AV+G P Sbjct: 494 GMYFTGDGARRDEDGYYWITGRVD-DVINVSGHRLGTAEVESALVSHELVAEAAVVGYPH 552 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 + G+ I A + E E + L W + ++ P + LP+ Sbjct: 553 DIKGQGIYAYVTLTRGTEESEE-------LRQELRQWVRKEIGALATPDLIQWATGLPKT 605 Query: 172 AMGKV 158 GK+ Sbjct: 606 RSGKI 610
>ACSA_XANAC (Q8PF09) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 6/131 (4%) Frame = -2 Query: 532 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 G + TGD D DGY+ I GR + D++ V G+++ E+E+ L+ H V E AV+G P Sbjct: 493 GSYFTGDGCRRDADGYYWITGRVD-DVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPH 551 Query: 352 EAYGEVICAII------VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLW 191 + G+ I A + P ED + L SW + ++ P P L Sbjct: 552 DVKGQGIYAYVTLIAGQTPSEDLHKE-------------LVSWVRKEIGPIASPDHLQWA 598 Query: 190 DSLPRNAMGKV 158 LP+ GK+ Sbjct: 599 PGLPKTRSGKI 609
>DHBF_BACSU (P45745) Dimodular nonribosomal peptide synthetase| Length = 2378 Score = 67.0 bits (162), Expect = 6e-11 Identities = 48/191 (25%), Positives = 87/191 (45%), Gaps = 8/191 (4%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 R +G +P + ++ + GV GEL + L + Y RP +T+E FI F Sbjct: 1841 RANSLIGCGIPDLGVYVLDERLQPVPPGVAGELYVSGAGLARGYLGRPGLTSERFIADPF 1900 Query: 526 -------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAV 368 ++TGD + DG +GR + + K+ G+++ EIEA L++H + + AV Sbjct: 1901 GPPGTRMYRTGDVARLRADGSLDYVGRADHQV-KIRGFRIELGEIEAALVQHPQLEDAAV 1959 Query: 367 LGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWD 188 + D+ + + A ++P E+ + AE L ++ ++L Y +P Sbjct: 1960 IVREDQPGDKRLAAYVIPSEETFDTAE-----------LRRYAAERLPDYMVPAAFVTMK 2008 Query: 187 SLPRNAMGKVN 155 LP GK++ Sbjct: 2009 ELPLTPNGKLD 2019 Score = 62.0 bits (149), Expect = 2e-09 Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 9/187 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDG--VGELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 +GKP+ + ++D+G + VGEL I L + Y+ RP++TAE F+ + Sbjct: 772 IGKPIWNTQV-YVLDNGLQPVPPGVVGELYIAGTGLARGYFHRPDLTAERFVADPYGPPG 830 Query: 526 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 ++TGD DG +GR + I K+ G+++ EI+AVL H + + AV+ Sbjct: 831 TRMYRTGDQARWRADGSLDYIGRADHQI-KIRGFRIELGEIDAVLANHPHIEQAAVVVRE 889 Query: 355 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 176 D+ + + A +V + A+ L + L Y +P+ D LP Sbjct: 890 DQPGDKRLAAYVV------------ADAAIDTAELRRYMGASLPDYMVPSAFVEMDELPL 937 Query: 175 NAMGKVN 155 GK++ Sbjct: 938 TPNGKLD 944
>ACSA_PSESM (Q885K7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 66.6 bits (161), Expect = 7e-11 Identities = 39/125 (31%), Positives = 63/125 (50%) Frame = -2 Query: 532 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 G + TGD DEDGY+ I GR + D++ V G+++ EIE+ ++ H V E AV+G+P Sbjct: 494 GMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESAMVAHPKVAEAAVVGVPH 552 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 + G+ I + A + AL E L +W + ++ P P + LP+ Sbjct: 553 DLKGQGIYVYVT------LNAGEEPSDALRTE-LRNWVRKEIGPIASPDFIQWAPGLPKT 605 Query: 172 AMGKV 158 GK+ Sbjct: 606 RSGKI 610
>PKSJ_BACSU (P40806) Putative polyketide synthase pksJ (PKS)| Length = 5045 Score = 66.6 bits (161), Expect = 7e-11 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 7/186 (3%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF---- 527 T+G+P+ + I GV GELCI + K Y+K+ E+T FID F Sbjct: 1467 TIGRPIANTQIYITDSQLAPVPAGVPGELCIAGDGVAKGYYKKEELTDSRFIDNPFEPGS 1526 Query: 526 --FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 ++TGD G +GR + + K+ G+++ +IE+ L EH +LEC V+ D Sbjct: 1527 KLYRTGDMARWLTGGRIEYIGRIDNQV-KIRGFRIELGDIESRLSEHPGILECVVVADMD 1585 Query: 352 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 + A K + +LT L + K+ L Y +P+ D +P Sbjct: 1586 N-----LAAYYTAKH---------ANASLTARELRHFVKNALPAYMVPSYFIQLDHMPLT 1631 Query: 172 AMGKVN 155 GK++ Sbjct: 1632 PNGKID 1637 Score = 47.4 bits (111), Expect = 5e-05 Identities = 42/183 (22%), Positives = 82/183 (44%), Gaps = 6/183 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +G P+P +I+ D ++G +G + S+ Y++RP++ F + G+F+TGD Sbjct: 376 IGSPIPGFSMRIVNDHNELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDGWFETGD 435 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVL-----LEHDTVLECAVLGLPDEA 347 + +G I GRT D + + G + IE+ + +E CAV L + Sbjct: 436 LGFL-RNGRLTITGRTK-DAIIINGINYYSHAIESAVEELPEIETSYTAACAV-RLGQNS 492 Query: 346 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 167 ++ + A+ EQ S+ +++ S Y +P + + +P+ A+ Sbjct: 493 TDQLAIFFVT---SAKLNDEQMSQLLRNIQSHVSQVIGVTPEYLLPVQK---EEIPKTAI 546 Query: 166 GKV 158 GK+ Sbjct: 547 GKI 549
>ACS2_CANAL (Q8NJN3) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) (Fragment) Length = 581 Score = 66.2 bits (160), Expect = 1e-10 Identities = 48/137 (35%), Positives = 73/137 (53%), Gaps = 10/137 (7%) Frame = -2 Query: 718 PLHGA--RKEGTVGKPLPRVEAKIIMDDGT----ETKDGVGELCIKS--PSLFKEYWKRP 563 PL G K G+ P ++A +I D T E D G L IK PS+ + +K Sbjct: 440 PLAGVVPNKPGSASYPFFGIDAALI-DPVTGVEIEGNDAEGVLAIKDHWPSMARTVYKNH 498 Query: 562 EVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 +++++ G++ TGD D DGY+ I GR + D++ V G++LS EIEA L+E Sbjct: 499 TKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGRVD-DVVNVSGHRLSTAEIEAALIEDK 557 Query: 388 TVLECAVLGLPDEAYGE 338 V E AV+G+ D+ G+ Sbjct: 558 KVSEAAVVGIHDDITGQ 574
>ACSA_MOUSE (Q9QXG4) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 66.2 bits (160), Expect = 1e-10 Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 9/196 (4%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETK-DGVGELCIKSP------SLFKEYWKR 566 PL GA K G+ P V + + + G E + + G L K P +++ + + Sbjct: 477 PLPGATPMKPGSASFPFFGVALQSLNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHTRF 536 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 + F G++ TGD D+DGY+ I GR + D++ V G+ LS E+E+ L+EH+ Sbjct: 537 ETTYFKKF--PGYYVTGDGCRRDQDGYYWITGRID-DMLNVSGHLLSTAEVESALVEHEA 593 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPT 206 V E AV+G P GE + + + P LT E L ++K+ P P Sbjct: 594 VAEAAVVGHPHPVKGECLYCFVTLCDG------HTFSPTLT-EELKKQIREKIGPIATPD 646 Query: 205 RLHLWDSLPRNAMGKV 158 + L + GK+ Sbjct: 647 YIQNAPGLLKPRSGKI 662
>DLTA_STRP6 (Q5XBN5) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 65.9 bits (159), Expect = 1e-10 Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 5/183 (2%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFK 521 +G P P II +DG E G GE+ + P++ K Y PE TAE+F + Sbjct: 323 IGYPKPDSPTYIIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYH 382 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAY 344 TGD ++ ED + GR + I K GY++ ++ L + V AV E Sbjct: 383 TGDIGSLTEDNILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHK 441 Query: 343 GEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMG 164 + + A IV K+ +ER ++ + +A+ + KD + Y +P++ DSLP G Sbjct: 442 VQNLLAYIVVKDGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNG 498 Query: 163 KVN 155 K++ Sbjct: 499 KID 501
>DLTA_STRP3 (Q8K744) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 65.9 bits (159), Expect = 1e-10 Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 5/183 (2%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFK 521 +G P P II +DG E G GE+ + P++ K Y PE TAE+F + Sbjct: 323 IGYPKPDSPTYIIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYH 382 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAY 344 TGD ++ ED + GR + I K GY++ ++ L + V AV E Sbjct: 383 TGDIGSLTEDNILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHK 441 Query: 343 GEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMG 164 + + A IV K+ +ER ++ + +A+ + KD + Y +P++ DSLP G Sbjct: 442 VQNLLAYIVVKDGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNG 498 Query: 163 KVN 155 K++ Sbjct: 499 KID 501
>DLTA_STRP1 (Q99ZA6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 65.9 bits (159), Expect = 1e-10 Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 5/183 (2%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFK 521 +G P P II +DG E G GE+ + P++ K Y PE TAE+F + Sbjct: 323 IGYPKPDSPTYIIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYH 382 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAY 344 TGD ++ ED + GR + I K GY++ ++ L + V AV E Sbjct: 383 TGDIGSLTEDNILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHK 441 Query: 343 GEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMG 164 + + A IV K+ +ER ++ + +A+ + KD + Y +P++ DSLP G Sbjct: 442 VQNLLAYIVVKDGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNG 498 Query: 163 KVN 155 K++ Sbjct: 499 KID 501
>ACSA_XANCP (Q8P3L1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 65.9 bits (159), Expect = 1e-10 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = -2 Query: 532 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 353 G + TGD D DGY+ I GR + D++ V G+++ E+E+ L+ H V E AV+G P Sbjct: 493 GSYFTGDGCRRDADGYYWITGRVD-DVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPH 551 Query: 352 EAYGEVICAII--VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 + G+ I A + + E E + L SW + ++ P P L LP Sbjct: 552 DVKGQGIYAYVTLIAGETPSEELH---------KELVSWVRKEIGPIASPDHLQWAPGLP 602 Query: 178 RNAMGKV 158 + GK+ Sbjct: 603 KTRSGKI 609
>DLTA_STRP8 (Q8P0J9) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 65.5 bits (158), Expect = 2e-10 Identities = 53/183 (28%), Positives = 86/183 (46%), Gaps = 5/183 (2%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFK 521 +G P P II +DG E G GE+ + P++ K Y PE TAE+F + Sbjct: 323 IGYPKPDSPTYIIDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYH 382 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAY 344 TGD ++ ED + GR + I K GY++ ++ L + V AV E Sbjct: 383 TGDIGSLTEDNILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHK 441 Query: 343 GEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMG 164 + + A IV K+ +ER ++ + +A+ + KD + Y +P++ DSLP G Sbjct: 442 VQNLLAYIVVKDGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNG 498 Query: 163 KVN 155 K++ Sbjct: 499 KID 501
>SRFAC_BACSU (Q08787) Surfactin synthetase subunit 3| Length = 1274 Score = 65.5 bits (158), Expect = 2e-10 Identities = 53/185 (28%), Positives = 80/185 (43%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +GKP+ I+ + G VGELCI + K Y R ++T E FI+ F Sbjct: 779 IGKPISNASVYILNEQSQLQPFGAVGELCISGMGVSKGYVNRADLTKEKFIENPFKPGET 838 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG GR + D +K+ G+++ EIE L E+ V + V+ E Sbjct: 839 LYRTGDLARWLPDGTIEYAGRID-DQVKIRGHRIELEEIEKQLQEYPGVKDAVVVADRHE 897 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + DA A ++ L+ E + + K +L Y +P D LP Sbjct: 898 S------------GDASINAYLVNRTQLSAEDVKAHLKKQLPAYMVPQTFTFLDELPLTT 945 Query: 169 MGKVN 155 GKVN Sbjct: 946 NGKVN 950
>ACSA_RHILO (Q98ET8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 65.1 bits (157), Expect = 2e-10 Identities = 51/200 (25%), Positives = 90/200 (45%), Gaps = 13/200 (6%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKS--PSLFKEYWKRPEVT 554 PL GA K G+ +P V+ +++ +G + G LCI P + + + Sbjct: 426 PLPGATDLKAGSATRPFFGVKPQLVDGEGKVLEGAADGNLCITDSWPGQMRTVYGDHDRF 485 Query: 553 AESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVL 380 +++ G + TGD D DGY+ I GR + D++ V G+++ E+E+ L+ HD V Sbjct: 486 VQTYFSTYKGKYFTGDGCRRDADGYYWITGRVD-DVINVSGHRMGTAEVESALVSHDKVS 544 Query: 379 ECAVLGLPDEAYGEVICAIIV------PKEDARERAEQASKPALTLEALTSWSKDKLAPY 218 E AV+G P + G+ I + + P ED R+ L + + ++ Sbjct: 545 EAAVVGYPHDIKGQGIYSYVTLMKGEEPTEDLRKE-------------LIAHVRKEIGAI 591 Query: 217 KIPTRLHLWDSLPRNAMGKV 158 P ++ LP+ GK+ Sbjct: 592 ASPDKIQFAPGLPKTRSGKI 611
>PPS1_BACSU (P39845) Peptide synthetase 1| Length = 2561 Score = 65.1 bits (157), Expect = 2e-10 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G PLP V ++ GV GELCI + K Y +P++T F + F Sbjct: 1820 IGSPLPNVHMYVLSQTDQIQPIGVAGELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGER 1879 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD +G +LGR + + K+ GY++ EIE+VLL+ V E AV D+ Sbjct: 1880 LYRTGDRACWLPNGTIRLLGRMDYQV-KINGYRIETEEIESVLLQTGLVREAAVAVQHDK 1938 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + A IVP D A +A ALT E L Y IP L ++P Sbjct: 1939 NGQAGLAAYIVP-SDVNTNALRA---ALTKE---------LPAYMIPAYLIPLVNMPLTL 1985 Query: 169 MGKVN 155 GK++ Sbjct: 1986 NGKLD 1990 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/141 (32%), Positives = 66/141 (46%), Gaps = 7/141 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFF---- 524 +GKP+P ++ GV GEL I + + Y RP +T E F++ F+ Sbjct: 776 IGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGER 835 Query: 523 --KTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 KTGD DG LGRT+ D +K+ GY++ EIEA L + V E AV D Sbjct: 836 MYKTGDVARWLPDGNVEFLGRTD-DQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDS 894 Query: 349 AYGEVICAIIVPKEDARERAE 287 E +CA + + RA+ Sbjct: 895 GEPE-LCAYVEGLQRNEVRAQ 914
>ACSA_CRYPV (Q27549) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 694 Score = 64.7 bits (156), Expect = 3e-10 Identities = 52/189 (27%), Positives = 87/189 (46%), Gaps = 8/189 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGE--LCIKS--PSLFKEYWKRP---EVTAESF 542 K G+ P +E I+ D + DG G LCIK+ P +F+ + E+ + F Sbjct: 469 KPGSATFPFFGIEPAILDPDTGKEIDGPGSGVLCIKNSWPGMFRGIFGAHYLHEIYTKPF 528 Query: 541 IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 ++ TGD V D+DGY I GR + D + V G++LS+ EIE L H + E A + Sbjct: 529 PK--YYFTGDGVLRDQDGYLWITGRID-DTINVSGHRLSSKEIEDALTNHFGIAEAAAVA 585 Query: 361 LPDEAYGEVICAIIVPKEDARERAE-QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 + + G + +V K+ + S P L + ++ P P + + ++ Sbjct: 586 IDHDVKGNALVCFVVLKDSGNRTFDLNNSSPHPFEYELRMCVRTQIGPVATPDHIIVVEN 645 Query: 184 LPRNAMGKV 158 +P+ GKV Sbjct: 646 IPKTRSGKV 654
>BACB_BACLI (O68007) Bacitracin synthetase 2 (BA2) [Includes: ATP-dependent| lysine adenylase (LysA) (Lysine activase); ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine activase); Ornithine racemase (EC 5.1.1.12)] Length = 2607 Score = 64.7 bits (156), Expect = 3e-10 Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID------GG 530 +GKPL I+ GV GEL I + + Y +PE+T E F+ G Sbjct: 1869 IGKPLDNTAFYILDPSLNPQPVGVYGELYIGGEGIARGYLNKPELTKERFVPNRFAAGGN 1928 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +KTGD DG LGR + + K+ G+++ EIE LLE+ + E V+ D+ Sbjct: 1929 MYKTGDLARWLPDGNVEFLGRIDHQV-KIRGFRIETGEIETKLLENQNISEAVVIDREDK 1987 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + +CA IV ++ L + D L Y +P+ + +P Sbjct: 1988 KGHKYLCAYIV------------ARAKTNTNELREYLSDHLPDYMLPSYFIQINKMPLTP 2035 Query: 169 MGKVN 155 GK++ Sbjct: 2036 NGKID 2040 Score = 57.0 bits (136), Expect = 6e-08 Identities = 51/186 (27%), Positives = 79/186 (42%), Gaps = 8/186 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI--DGG--FF 524 +GKPL + I G GV GEL I + + Y +T +F+ + G + Sbjct: 827 IGKPLSNYKVYIADQYGRPQPVGVPGELLIGGEGVARGYLNHETLTKAAFVVDESGERVY 886 Query: 523 KTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAY 344 +TGD DG LGR ++ + K+ GY++ EIE LL +D + E V+ D+ Sbjct: 887 RTGDLARWLSDGNIEFLGRIDSQV-KIRGYRIELEEIEHRLLMNDNINEAIVVAKEDQEN 945 Query: 343 GEVICAIIV---PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 + +CA I D + E+ +K L Y IP+ D +PR Sbjct: 946 SKYLCAYIAFNNKNADIEQVQERLAK--------------DLPEYMIPSCFIKLDQIPRT 991 Query: 172 AMGKVN 155 GK + Sbjct: 992 INGKAD 997
>PRPE_ECOLI (P77495) Propionate--CoA ligase (EC 6.2.1.17) (Propionyl-CoA| synthetase) Length = 628 Score = 64.3 bits (155), Expect = 4e-10 Identities = 45/143 (31%), Positives = 66/143 (46%), Gaps = 1/143 (0%) Frame = -2 Query: 583 KEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAV 404 K YW S + T D D DGY ILGRT+ D++ V G++L EIE Sbjct: 463 KTYW--------SLFSRPVYATFDWGIRDADGYHFILGRTD-DVINVAGHRLGTREIEES 513 Query: 403 LLEHDTVLECAVLGLPDEAYGEVICAIIVPKE-DARERAEQASKPALTLEALTSWSKDKL 227 + H V E AV+G+ D G+V A ++PKE D+ E + A + AL ++ Sbjct: 514 ISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALVD---SQI 570 Query: 226 APYKIPTRLHLWDSLPRNAMGKV 158 + P + LP+ GK+ Sbjct: 571 GNFGRPAHVWFVSQLPKTRSGKM 593
>ACSA_AGRRH (Q9KWA3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 64.3 bits (155), Expect = 4e-10 Identities = 54/199 (27%), Positives = 93/199 (46%), Gaps = 12/199 (6%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWKR 566 PL GA K G+ +P + +++ +G + G LCI ++ S++ ++ +R Sbjct: 425 PLPGATDLKPGSATRPFFGIRPELVDAEGKLIEGAADGNLCIADSWPGQARSVYGDH-ER 483 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 T S +G +F TGD D DGY+ I GR + D++ V G++L E+E+ L+ H Sbjct: 484 FIQTYFSTYEGKYF-TGDGCRRDADGYYWITGRVD-DVLNVSGHRLGTAEVESALVSHHL 541 Query: 385 VLECAVLGLPDEAYGEVI---CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYK 215 V E AV+G P G+ I ++ E + E +Q L + ++ P Sbjct: 542 VSEAAVVGYPHNIKGQGIYCYVTLMAGSEGSEELRQQ----------LVKHVRAEIGPIA 591 Query: 214 IPTRLHLWDSLPRNAMGKV 158 P ++ LP+ GK+ Sbjct: 592 SPDKIQFAPGLPKTRSGKI 610
>ACSA1_PSEAE (Q9I558) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 651 Score = 63.9 bits (154), Expect = 5e-10 Identities = 51/197 (25%), Positives = 91/197 (46%), Gaps = 10/197 (5%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCI------KSPSLFKEYWKR 566 PL GA K G+ KP V ++ + G + G L I ++ +LF ++ + Sbjct: 425 PLPGAHAMKPGSAAKPFFGVVPALVDNLGNLIEGAAEGNLVILDSWPGQARTLFGDHDRF 484 Query: 565 PEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDT 386 + ++F G + TGD DEDGY+ I GR + D++ V G+++ E+E+ ++ H Sbjct: 485 VDTYFKTF--KGMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEVESAMVAHPK 541 Query: 385 VLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTL-EALTSWSKDKLAPYKIP 209 V E AV+G+ + G+ I + +P+ L + L W + ++ P P Sbjct: 542 VAEAAVVGMQHDIKGQGIYVYVT--------LNSGVEPSEALRQELKQWVRREIGPIATP 593 Query: 208 TRLHLWDSLPRNAMGKV 158 + LP+ GK+ Sbjct: 594 DVIQWAPGLPKTRSGKI 610
>VRAA_STAAW (Q7A1Q0) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 63.2 bits (152), Expect = 8e-10 Identities = 46/178 (25%), Positives = 85/178 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG P VE K D +G+G +CIKS +F Y V+ + + +F T D Sbjct: 290 SVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVTND 340 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G++ Sbjct: 341 NGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQI- 397 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 398 -GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAU (Q9KWK5) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 63.2 bits (152), Expect = 8e-10 Identities = 46/178 (25%), Positives = 85/178 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG P VE K D +G+G +CIKS +F Y V+ + + +F T D Sbjct: 290 SVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVTND 340 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G++ Sbjct: 341 NGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQI- 397 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 398 -GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAS (Q6GBR2) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 63.2 bits (152), Expect = 8e-10 Identities = 46/178 (25%), Positives = 85/178 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG P VE K D +G+G +CIKS +F Y V+ + + +F T D Sbjct: 290 SVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVTND 340 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G++ Sbjct: 341 NGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQI- 397 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 398 -GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAN (Q7A769) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 63.2 bits (152), Expect = 8e-10 Identities = 46/178 (25%), Positives = 85/178 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG P VE K D +G+G +CIKS +F Y V+ + + +F T D Sbjct: 290 SVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVTND 340 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G++ Sbjct: 341 NGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQI- 397 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 398 -GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAM (Q99W34) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 63.2 bits (152), Expect = 8e-10 Identities = 46/178 (25%), Positives = 85/178 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG P VE K D +G+G +CIKS +F Y V+ + + +F T D Sbjct: 290 SVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVTND 340 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G++ Sbjct: 341 NGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQI- 397 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 398 -GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAC (Q5HIA1) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 63.2 bits (152), Expect = 8e-10 Identities = 46/178 (25%), Positives = 85/178 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG P VE K D +G+G +CIKS +F Y V+ + + +F T D Sbjct: 290 SVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVTND 340 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G++ Sbjct: 341 NGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQI- 397 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 398 -GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>FAD11_MYCTU (Q10776) Putative fatty-acid--CoA ligase fadD11 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 571 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/109 (34%), Positives = 53/109 (48%) Frame = -2 Query: 724 SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAES 545 S+P G + GTVGK LP ++ KI D GE ++ P + K Y K P TAE+ Sbjct: 341 SHPRDG--RLGTVGKLLPGLQGKIAED---------GEYLVRGPLVMKGYRKEPAKTAEA 389 Query: 544 FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLL 398 G+ TGD +D DGY ++ R I+ G +S IE +L Sbjct: 390 IDSDGWLHTGDVFDIDSDGYLRVVDRKKELIINAAGKNMSPANIENTIL 438
>ACSA2_PSEPK (Q88DW6) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 644 Score = 61.6 bits (148), Expect = 2e-09 Identities = 50/194 (25%), Positives = 90/194 (46%), Gaps = 7/194 (3%) Frame = -2 Query: 718 PLHGAR--KEGTVGKPLPRVEAKIIMDDGTETKD-GVGELCIKS--PSLFKEYWKRPEVT 554 PL G + K G +P+ V+ ++ + G + G G L IK+ P + + + Sbjct: 421 PLPGTQSLKPGCATQPMFGVQPVLLDEKGKLIEGPGAGVLAIKASWPGQIRSVYGDHQRM 480 Query: 553 AESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVL 380 +++ G++ TGD D DG + I GR + D++ V G+++ E+E+ L+ HD+V Sbjct: 481 VDTYFKPLPGYYFTGDGARRDADGDYWITGRID-DVINVSGHRIGTAEVESALVLHDSVA 539 Query: 379 ECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL 200 E AV+G P + G+ + A + L E L SK+ + + P + Sbjct: 540 EAAVVGYPHDLKGQGVYAFVTTMNGV------TPDDTLKAELLALVSKE-IGSFAKPELI 592 Query: 199 HLWDSLPRNAMGKV 158 +LP+ GK+ Sbjct: 593 QWAPALPKTRSGKI 606
>PPS3_BACSU (P39847) Peptide synthetase 3| Length = 2555 Score = 61.6 bits (148), Expect = 2e-09 Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 7/185 (3%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----- 527 +G+P+ A I+ G G VGELC+ + + Y RP++T E F+ F Sbjct: 1815 IGRPVGNSTAFILNQWGVLQPVGAVGELCVGGDGVARGYLGRPDLTKEKFVPHPFAPGDR 1874 Query: 526 -FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 ++TGD DG +GR + D +KV GY++ EIE L + D V E AVL + Sbjct: 1875 LYRTGDLARWLSDGTIEYVGRID-DQVKVRGYRVELGEIETALRQIDGVKEAAVLARTAQ 1933 Query: 349 AYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNA 170 + + I + K E + S L Y IP + ++LP + Sbjct: 1934 TGSKELFGYI------------SVKAGTNAEQVRSLLARSLPNYMIPAYIIEMETLPLTS 1981 Query: 169 MGKVN 155 GK+N Sbjct: 1982 NGKLN 1986 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/141 (32%), Positives = 66/141 (46%), Gaps = 7/141 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFF---- 524 +GKP+P ++ GV GEL I + + Y RP +T E F++ F+ Sbjct: 782 IGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYLGER 841 Query: 523 --KTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 KTGD DG LGRT+ D +K+ GY++ EIEA L + V E AV D Sbjct: 842 MYKTGDVARWLPDGNVEFLGRTD-DQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDS 900 Query: 349 AYGEVICAIIVPKEDARERAE 287 E +CA + + RA+ Sbjct: 901 GEPE-LCAYVEGLQRNEVRAQ 920
>VRAA_STAAR (Q6GJ94) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 61.2 bits (147), Expect = 3e-09 Identities = 44/178 (24%), Positives = 85/178 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG P VE K D +G+G +C+KS +F Y V+ + + +F T D Sbjct: 290 SVGVLFPNVELKTTNHD----HNGIGTICVKSNMMFSGY-----VSEQCINNDEWFVTND 340 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 V E Y + GR + D++ +GG + +E +L + ++ E ++G+P+E +G++ Sbjct: 341 NGYVKEQ-YLYLTGRQH-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQI- 397 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +++ D LT + + + K+ Y+IP+ +H + + A GK+ Sbjct: 398 -GVLLYSGDV----------TLTHKNVKQFLNKKVKRYEIPSMIHHVEKMYYTASGKI 444
>ACSA_XYLFT (Q87C00) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 8/139 (5%) Frame = -2 Query: 550 ESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 + FID F + TGD D DGY+ I GR + D++ + G+++ EIE+ L+ H Sbjct: 481 QRFIDTYFRTYPNTYFTGDGCRRDADGYYWITGRVD-DVINISGHRIGTAEIESTLVAHP 539 Query: 388 TVLECAVLGLPDEAYGEVICAII--VPKEDARERAEQASKPALTLEALTSWSKDKLAPYK 215 V E AV+G P G+ I A + + E E Q L +W + ++ Sbjct: 540 KVAEAAVVGFPHPIKGQGIYAYVTLITGETPSEALHQ---------ELLTWVRKEIGAIA 590 Query: 214 IPTRLHLWDSLPRNAMGKV 158 IP + +LP+ GK+ Sbjct: 591 IPDHVQWASNLPKTRSGKI 609
>VRAA_STAEQ (Q5HRH4) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 453 Score = 60.5 bits (145), Expect = 5e-09 Identities = 49/189 (25%), Positives = 90/189 (47%) Frame = -2 Query: 724 SNPLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAES 545 S+P H +VGK P VE +++ D D VG L ++S +F Y +S Sbjct: 281 SSPAH------SVGKLFPHVETRLLNQDD----DAVGLLAVRSEMVFSGY------VGQS 324 Query: 544 FIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL 365 +G + KTGD + F++ GR +D + VGG + IE+++++ + + E V+ Sbjct: 325 NQEGSWIKTGDFAYIKNQHLFLV-GR-ESDRIIVGGINVYPTAIESLIMDIEGIDEALVI 382 Query: 364 GLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 185 G+P +GE+ AI++ + K L + S+ +L+ ++P++L D Sbjct: 383 GIPHAKFGEI--AILL----------YSGKVQLNYRQIKSFLMKQLSRQEVPSKLKKIDH 430 Query: 184 LPRNAMGKV 158 + GK+ Sbjct: 431 MIYTESGKI 439
>PRPE_SALTY (P55912) Propionate--CoA ligase (EC 6.2.1.17) (Propionyl-CoA| synthetase) Length = 628 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/142 (26%), Positives = 68/142 (47%) Frame = -2 Query: 583 KEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAV 404 K YW S + + T D D +GY+ ILGRT+ D++ + G++L EIE Sbjct: 463 KTYW--------SLFNRQVYATFDWGIRDAEGYYFILGRTD-DVINIAGHRLGTREIEES 513 Query: 403 LLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLA 224 + + V E AV+G+ D G+V A ++PK+ +A++ A+ + +++ Sbjct: 514 ISSYPNVAEVAVVGIKDALKGQVAVAFVIPKQSDTLADREAARD--EENAIMALVDNQIG 571 Query: 223 PYKIPTRLHLWDSLPRNAMGKV 158 + P + LP+ GK+ Sbjct: 572 HFGRPAHVWFVSQLPKTRSGKM 593
>DLTA_LACRH (P35854) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 506 Score = 58.9 bits (141), Expect = 2e-08 Identities = 49/186 (26%), Positives = 84/186 (45%), Gaps = 8/186 (4%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGG---FFK 521 +G P ++ + G + G GEL I PS+ K Y P+ TA +F G ++ Sbjct: 321 IGYAKPDTNVYVVDEQGEQVSAGTEGELMIVGPSVSKGYLNNPDKTAAAFFKAGNQRGYR 380 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 +GD VT+ DG GRT+ + K+ GY++ +++ L + + + + + D+ + Sbjct: 381 SGDLVTMTADGMVFYRGRTDFQV-KLHGYRIELEDVDHNLNQVSYIKQASTVPRYDKDHK 439 Query: 340 E---VICAIIVPKE-DARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 173 + A+ P + D+ + QA K L + Y IP R+ D LP Sbjct: 440 VAQLIAFAVAKPNDFDSEMKLTQAIKAEL---------GKMVMEYMIPQRIIYRDQLPLT 490 Query: 172 AMGKVN 155 A GKV+ Sbjct: 491 ANGKVD 496
>ACSA_XYLFA (Q9PB89) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 58.9 bits (141), Expect = 2e-08 Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 8/139 (5%) Frame = -2 Query: 550 ESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 + FID F + TGD D DGY+ I GR + D++ + G+++ EIE+ L+ H Sbjct: 481 QRFIDTYFRTYPNTYFTGDGCRRDADGYYWITGRVD-DVINISGHRIGTAEIESTLVAHP 539 Query: 388 TVLECAVLGLPDEAYGEVICAII--VPKEDARERAEQASKPALTLEALTSWSKDKLAPYK 215 V E AV+G P G+ I A + + E E Q L +W + ++ Sbjct: 540 KVAEAAVVGFPHPIKGQGIYAYVTLITGETPSEALHQ---------ELLTWVRKEIGAIA 590 Query: 214 IPTRLHLWDSLPRNAMGKV 158 P + +LP+ GK+ Sbjct: 591 TPDHVQWAPNLPKTRSGKI 609
>AAS_YERPS (Q667F1) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 57.0 bits (136), Expect = 6e-08 Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 9/153 (5%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------T 554 A K TVG+ LP +EA++I G G L ++ P++ + Y + P V Sbjct: 527 AAKVNTVGRILPGMEARLINVPGIAQG---GRLQLRGPNIMRGYLRVENPGVLEQPSAEN 583 Query: 553 AESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 A+ +D ++ TGD VT+DE G+ I GR K+ G +S +E + + + Sbjct: 584 AQGELDANWYDTGDIVTLDEQGFCAIRGRVKR-FAKLAGEMVSLESVEQLAISLSPEGQH 642 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARERAEQASK 275 A D A GE + E RER +A++ Sbjct: 643 AAAAKTDSAKGEALVLFTTDSEITRERLIKAAR 675
>DLTA_LACPL (Q88VM6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 508 Score = 57.0 bits (136), Expect = 6e-08 Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 5/172 (2%) Frame = -2 Query: 655 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESF--IDG-GFFKTGDTVTVDEDG 488 ++ ++G +G GEL I PS+ K Y E TA++F +DG + +GD T+D DG Sbjct: 333 VVDENGEAVPNGTEGELIIAGPSVSKGYLNNSEKTAKAFFELDGQPAYHSGDIGTMDADG 392 Query: 487 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV-ICAIIVPK 311 F GR + I K+ GY++ E++ L + + + + D+ + + A +VPK Sbjct: 393 LFRYRGRVDFQI-KMHGYRIELEEVDHFLAQQQHIKQAVAVPKYDKEHKVTQMIAYVVPK 451 Query: 310 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + E S ALT A+ + + Y IP R SLP GK++ Sbjct: 452 PNDFE-----SDFALT-TAIKKDLQGMMMEYMIPQRFVYQTSLPLTPNGKID 497
>ANGR_VIBAN (P19828) Protein angR| Length = 1048 Score = 57.0 bits (136), Expect = 6e-08 Identities = 54/181 (29%), Positives = 83/181 (45%), Gaps = 4/181 (2%) Frame = -2 Query: 685 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESF--IDG-GFFKT 518 G PLPR + +++ D G + D V GEL I + Y+ T F IDG +++T Sbjct: 771 GYPLPRQQYRVVDDLGRDCPDWVAGELWIGGDGIALGYFDDELKTQAQFLHIDGHAWYRT 830 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD DG LGR + + KVGGY++ EIE L V + + ++ + Sbjct: 831 GDMGCYWPDGTLEFLGRRDKQV-KVGGYRIELGEIEVALNNIPGVQRAVAIAVGNK--DK 887 Query: 337 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 + A IV E+A + P L E + +L Y +P R+ ++ P A GKV Sbjct: 888 TLAAFIVMDS---EQAPIVTAP-LDAEEVQLLLNKQLPNYMVPKRIIFLETFPLTANGKV 943 Query: 157 N 155 + Sbjct: 944 D 944
>DLTA_BACSU (P39581) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 503 Score = 56.2 bits (134), Expect = 1e-07 Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 4/182 (2%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI--DGGF-FK 521 VG P + I+ ++G +G GE+ I PS+ + Y PE+T ++F +G + ++ Sbjct: 320 VGFAKPDMNIFIMDEEGQPLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFFSHEGQWAYR 379 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD + +DG GR + I K+ GY++ EIE + + V V+ Sbjct: 380 TGDAGFI-QDGQIFCQGRLDFQI-KLHGYRMELEEIEFHVRQSQYVRSAVVIPYQPNGTV 437 Query: 340 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 161 E + A IVP+E E+ Q + A+ E S L Y IP + D + A GK Sbjct: 438 EYLIAAIVPEEHEFEKEFQLTS-AIKKELAAS-----LPAYMIPRKFIYQDHIQMTANGK 491 Query: 160 VN 155 ++ Sbjct: 492 ID 493
>SID2_USTMA (O43103) Ferrichrome siderophore peptide synthetase (EC 6.-.-.-)| Length = 3947 Score = 56.2 bits (134), Expect = 1e-07 Identities = 48/191 (25%), Positives = 80/191 (41%), Gaps = 9/191 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMD-DGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFID---- 536 K +G LP V + D K VGEL + P L + Y P TA+ F Sbjct: 578 KAPNIGVALPTVSCHALDKYDQIVIKGAVGELVLGGPQLARGYVGDPVKTADKFFPHPQL 637 Query: 535 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLE-HDTVLECAVLGL 359 G ++TGD V ++ F LGR + D +K+ G ++ LEI A + HD + + + Sbjct: 638 GRVYRTGDLVRQLDNQEFEYLGRID-DQVKINGIRIELLEINAAIKNSHDKIKDSETMAF 696 Query: 358 P---DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWD 188 +E+ ++I +P + + L + +KD L Y +P + Sbjct: 697 SKKDNESEQQIINFSALPGGEPGQLLRTDQDAIAVARELQANAKDSLPSYMVPNLFVILS 756 Query: 187 SLPRNAMGKVN 155 PR + K++ Sbjct: 757 HFPRTSSAKID 767 Score = 40.4 bits (93), Expect = 0.006 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 10/148 (6%) Frame = -2 Query: 619 VGELCIKSPSLFKEYWKRPEVTAESFI---DG-GFFKTGDTVTVDEDGYFIILGRTNAD- 455 +GEL + P L Y+ R E+TAE FI DG ++TGD D LGR +D Sbjct: 2822 IGELAVGGPQLADCYYGREELTAEKFILLEDGTRVYRTGDLGRFLVDDTVECLGRIGSDR 2881 Query: 454 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG--EVICAIIVPKEDARERAEQA 281 +KV G ++ E+ +V+ V + V L + G +++ + + A++ Sbjct: 2882 QVKVNGQRMELDEVCSVISAQAGVYDADVQYLKHPSMGSKQLVAFVAAAETQAKQGDMDV 2941 Query: 280 SKPALTLE---ALTSWSKDKLAPYKIPT 206 ++ L + +LA Y +PT Sbjct: 2942 RDDDKAIDLCIRLEQEAAKRLATYMVPT 2969 Score = 37.7 bits (86), Expect = 0.036 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTET----KDGVGELCIKSPSLFKEYWKRPEVTAESFIDG 533 + +G P P + ++ D + + GEL I + K Y RP+ ++ G Sbjct: 1713 RPSNIGAPFPGTQYLVLKDVNGQLVPTLRGEPGELYIGGEQVAKGYLNRPDSSSFITYQG 1772 Query: 532 G-FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVL 401 ++TGD V + LGR + +KV G +L E++A L Sbjct: 1773 QQIYRTGDMVRLHPSDEAEYLGRIDGSQVKVRGARLELAEVDAAL 1817
>AAS_YERPE (Q74RZ6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 55.5 bits (132), Expect = 2e-07 Identities = 43/147 (29%), Positives = 66/147 (44%), Gaps = 9/147 (6%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------T 554 A K TVG+ LP +EA++I G G L ++ P++ + Y + P V Sbjct: 527 AAKVNTVGRILPGMEARLINVPGIAQG---GRLQLRGPNIMRGYLRVENPGVLEQPSAEN 583 Query: 553 AESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 A+ +D ++ TGD VT+DE G+ I GR K+ G +S +E + + + Sbjct: 584 AQGELDANWYDTGDIVTLDEQGFCAIRGRVKR-FAKLAGEMVSLESVEQLAISLSPEGQH 642 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARER 293 A D A GE + E RER Sbjct: 643 AAAAKTDSAKGEALVLFTTDSEITRER 669
>VRAA_STAES (Q8CQ67) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 411 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/119 (29%), Positives = 62/119 (52%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VGK P VE +++ D D VG L ++S +F Y +S +G + KTGD Sbjct: 286 SVGKLFPHVETRLLNQDD----DAVGLLAVRSEMVFSGY------VGQSNQEGAWIKTGD 335 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 335 + F++ GR +D + VGG + IE+++++ + + E V+G+P +GE+ Sbjct: 336 FAYIKNQHLFLV-GR-ESDRIIVGGINVYPTAIESLIMDIEGIDEALVIGIPHAKFGEI 392
>DLTA_STRR6 (P0A399) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 54.7 bits (130), Expect = 3e-07 Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 7/174 (4%) Frame = -2 Query: 655 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 488 II ++G + +G GE+ + P++ K Y PE TAE+F D + TGD T+ ++G Sbjct: 338 IIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEG 397 Query: 487 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP---DEAYGEVICAIIV 317 + GR + I K GY++ LE + L +E AV +P + + + A ++ Sbjct: 398 LLLYGGRMDFQI-KFNGYRIE-LEDVSQNLNKSRFIESAV-AVPRYNKDHKVQNLLAYVI 454 Query: 316 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 K+ RE+ E + +A+ D + Y +P++ DSLP GK++ Sbjct: 455 LKDGVREQFE---RDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKID 505
>DLTA_STRPN (P0A398) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 54.7 bits (130), Expect = 3e-07 Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 7/174 (4%) Frame = -2 Query: 655 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 488 II ++G + +G GE+ + P++ K Y PE TAE+F D + TGD T+ ++G Sbjct: 338 IIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEG 397 Query: 487 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP---DEAYGEVICAIIV 317 + GR + I K GY++ LE + L +E AV +P + + + A ++ Sbjct: 398 LLLYGGRMDFQI-KFNGYRIE-LEDVSQNLNKSRFIESAV-AVPRYNKDHKVQNLLAYVI 454 Query: 316 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 K+ RE+ E + +A+ D + Y +P++ DSLP GK++ Sbjct: 455 LKDGVREQFE---RDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKID 505
>LCFH_HAEIN (P44446) Putative long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase) (LACS) Length = 607 Score = 53.9 bits (128), Expect = 5e-07 Identities = 38/132 (28%), Positives = 63/132 (47%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 ++G +P+ E KI ++ E+ ++ + K Y+K+PE TA++F + GF KTGD Sbjct: 401 SIGTLMPKAEVKIGENN---------EILVRGGMVMKGYYKKPEETAQAFTEDGFLKTGD 451 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 DE G I R ++MK K A + + D +E + + Y + Sbjct: 452 AGEFDEQGNLFITDRIK-ELMKTSNGKYIAPQYIESKIGKDKFIEQIAIIADAKKY---V 507 Query: 331 CAIIVPKEDARE 296 A+IVP D+ E Sbjct: 508 SALIVPCFDSLE 519
>ACVS_NOCLA (P27743) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3649 Score = 53.9 bits (128), Expect = 5e-07 Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 11/130 (8%) Frame = -2 Query: 709 GARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDG 533 G T+G PL ++ D G VGEL + + + Y RPE+T E F+ Sbjct: 2704 GDAYRNTLGAPLGNTRLYVLGDGMKLLPTGAVGELYLAGDCVTEGYLHRPELTRERFLPN 2763 Query: 532 GF----------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTV 383 F ++TGD V DG LGR +A + K+ G ++ E+EA L V Sbjct: 2764 PFAAESGRFPMIYRTGDVVRRGPDGELQYLGRNDAQV-KINGLRIEPGEVEAALAGCSGV 2822 Query: 382 LECAVLGLPD 353 +CAV+ D Sbjct: 2823 RQCAVVAGAD 2832 Score = 51.6 bits (122), Expect = 2e-06 Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 15/198 (7%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFI---- 539 R++ ++G+PL V+ ++ + G +GEL I + Y R ++TAE F Sbjct: 568 RRDRSIGRPLRNVKWYVLSQGLKQLPIGAIGELYIGGCGVAPGYLNRDDLTAERFTANPF 627 Query: 538 ----------DGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 +G ++TGD V +G +GR + + K+ G ++ EIEA E Sbjct: 628 QTEEEKARGRNGRLYRTGDLARVLLNGEVEFMGRADFQL-KLNGVRVEPGEIEAQATEFP 686 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIP 209 V +C V+ + A G+ ED E AE L ++ + +L +P Sbjct: 687 GVKKCVVVA-KENATGDRHLVGYYLVEDGAEVAEAD---------LIAFLEQRLIRIMVP 736 Query: 208 TRLHLWDSLPRNAMGKVN 155 R+ S+P N GKV+ Sbjct: 737 ARMVRLTSIPVNVNGKVD 754 Score = 48.1 bits (113), Expect = 3e-05 Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 14/170 (8%) Frame = -2 Query: 622 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGY 485 G+GEL I + + Y R ++TA+ F++ F +KTGD V +G Sbjct: 1684 GIGELYIGGIGVTRGYLNREDLTADRFVENPFQTAEERRLGENGRLYKTGDLVRWLPNGE 1743 Query: 484 FIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED 305 LGRT+ + K+ G ++ E+EA L + V+ V+ + + V +++ Sbjct: 1744 VEYLGRTDLQV-KIRGQRVELGEVEAALSSYPGVVRSLVVAREHAVGQKYLVGFYVGEQE 1802 Query: 304 ARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 E + L W + KL +P R+ +P GK++ Sbjct: 1803 FDE------------QDLKQWMRKKLPESVVPARVLRITDIPVTPSGKLD 1840
>ACSA_PRB01 (Q9F7R5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 641 Score = 53.9 bits (128), Expect = 5e-07 Identities = 28/67 (41%), Positives = 39/67 (58%) Frame = -2 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD DEDGYF I GR + D++ V G++L EIE+ L+ H + E AV+G G Sbjct: 491 TGDGARRDEDGYFWITGRVD-DVLNVSGHRLGTAEIESALVLHPKIAEAAVVGFDHPIKG 549 Query: 340 EVICAII 320 + I A + Sbjct: 550 QGIYAFV 556
>DLTA_STAAW (P68878) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAU (P68877) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAS (Q6GAZ4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAR (Q6GIF6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAN (P99107) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAM (P68876) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAC (Q5HHF2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>ACVS2_PENCH (P26046) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3791 Score = 53.5 bits (127), Expect = 6e-07 Identities = 52/211 (24%), Positives = 88/211 (41%), Gaps = 23/211 (10%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESF 542 P R + ++G+ + + ++ +D T G VGEL + + + Y R +VTAE F Sbjct: 1725 PFPERRMDKSIGQQVHNSTSYVLNEDMKRTPIGAVGELYLGGEGVVRGYHNRADVTAERF 1784 Query: 541 IDGGF--------------FKTGDTV--TVDEDGYFIILGRTNADIMKVGGYKLSALEIE 410 I F +KTGD V G LGR + + K+ G ++ EIE Sbjct: 1785 IPNPFQSEEDKREGRNSRLYKTGDLVRWIPGSSGEVEYLGRNDFQV-KIRGLRIELGEIE 1843 Query: 409 AVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQ------ASKPALTLEALT 248 A+L + + + V+ +D RE A++ + AL A+ Sbjct: 1844 AILSSYHGIKQSVVIA-----------------KDCREGAQKFLVGYYVADAALPSAAIR 1886 Query: 247 SWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + +L Y +P+RL L P GK++ Sbjct: 1887 RFMQSRLPGYMVPSRLILVSKFPVTPSGKLD 1917 Score = 53.5 bits (127), Expect = 6e-07 Identities = 56/203 (27%), Positives = 82/203 (40%), Gaps = 20/203 (9%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 RK+ ++G+P+ V+ I+ G GEL I + K Y RPE+T FI F Sbjct: 640 RKDTSLGRPVRNVKCYILNPSLKRVPIGATGELHIGGLGISKGYLNRPELTPHRFIPNPF 699 Query: 526 --------------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 +KTGD +G LGR + I K+ G ++ EIE +L + Sbjct: 700 QTDCEKQLGINSLMYKTGDLARWLPNGEVEYLGRADFQI-KLRGIRIEPGEIETMLAMYP 758 Query: 388 TVLECAVLGL-----PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLA 224 V V+ P+E E + V + A+ L S+ + KL Sbjct: 759 RVRTSLVVSKKLRNGPEETTNEHLVGYYVCDSASVSEAD-----------LLSFLEKKLP 807 Query: 223 PYKIPTRLHLWDSLPRNAMGKVN 155 Y IPTRL +P N GK + Sbjct: 808 RYMIPTRLVQLSQIPVNVNGKAD 830
>ACSL1_RAT (P18163) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain-fatty-acid--CoA ligase, liver isozyme) Length = 699 Score = 53.5 bits (127), Expect = 6e-07 Identities = 41/136 (30%), Positives = 62/136 (45%), Gaps = 2/136 (1%) Frame = -2 Query: 715 LHGARKEGTVGKPLPRVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESF 542 L G G VG P+P K++ D + G GE+C+K ++FK Y K P TAE+ Sbjct: 472 LPGDWTAGHVGAPMPCNYIKLVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEAL 531 Query: 541 IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 G+ TGD +G I+ R G ++ +IE + L + V + V G Sbjct: 532 DKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHG 591 Query: 361 LPDEAYGEVICAIIVP 314 E+ + AI+VP Sbjct: 592 ---ESLQAFLIAIVVP 604
>ACVS1_PENCH (P19787) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3746 Score = 53.5 bits (127), Expect = 6e-07 Identities = 52/211 (24%), Positives = 88/211 (41%), Gaps = 23/211 (10%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESF 542 P R + ++G+ + + ++ +D T G VGEL + + + Y R +VTAE F Sbjct: 1693 PFPERRMDKSIGQQVHNSTSYVLNEDMKRTPIGSVGELYLGGEGVVRGYHNRADVTAERF 1752 Query: 541 IDGGF--------------FKTGDTV--TVDEDGYFIILGRTNADIMKVGGYKLSALEIE 410 I F +KTGD V G LGR + + K+ G ++ EIE Sbjct: 1753 IPNPFQSEEDKREGRNSRLYKTGDLVRWIPGSSGEVEYLGRNDFQV-KIRGLRIELGEIE 1811 Query: 409 AVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQ------ASKPALTLEALT 248 A+L + + + V+ +D RE A++ + AL A+ Sbjct: 1812 AILSSYHGIKQSVVIA-----------------KDCREGAQKFLVGYYVADAALPSAAIR 1854 Query: 247 SWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + + +L Y +P+RL L P GK++ Sbjct: 1855 RFMQSRLPGYMVPSRLILVSKFPVTPSGKLD 1885 Score = 53.5 bits (127), Expect = 6e-07 Identities = 56/203 (27%), Positives = 82/203 (40%), Gaps = 20/203 (9%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 RK+ ++G+P+ V+ I+ G GEL I + K Y RPE+T FI F Sbjct: 610 RKDTSLGRPVRNVKCYILNPSLKRVPIGATGELHIGGLGISKGYLNRPELTPHRFIPNPF 669 Query: 526 --------------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 +KTGD +G LGR + I K+ G ++ EIE +L + Sbjct: 670 QTDCEKQLGINSLMYKTGDLARWLPNGEVEYLGRADFQI-KLRGIRIEPGEIETMLAMYP 728 Query: 388 TVLECAVLGL-----PDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLA 224 V V+ P+E E + V + A+ L S+ + KL Sbjct: 729 RVRTSLVVSKKLRNGPEETTNEHLVGYYVCDSASVSEAD-----------LLSFLEKKLP 777 Query: 223 PYKIPTRLHLWDSLPRNAMGKVN 155 Y IPTRL +P N GK + Sbjct: 778 RYMIPTRLVQLSQIPVNVNGKAD 800
>HTS1_COCCA (Q01886) HC-toxin synthetase (EC 6.3.2.-) (HTS)| Length = 5218 Score = 53.1 bits (126), Expect = 8e-07 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 26/181 (14%) Frame = -2 Query: 619 VGELCIKSPSLFKEYWKRPEVTAESFIDG----------------GFFKTGDTVTVDEDG 488 +GEL I+S L +Y RP+ T +F+ F++TGD V +DG Sbjct: 547 IGELLIESGHLADKYLNRPDRTEAAFLSDLPWIPNYEGDSVRRGRRFYRTGDLVRYCDDG 606 Query: 487 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL---GLPDEAYGEVICAIIV 317 I +GR++ I K+ G ++ ++EA L T + AV+ P EA +I ++ Sbjct: 607 SLICVGRSDTQI-KLAGQRVELGDVEAHLQSDPTTSQAAVVFPRSGPLEA--RLIALLVT 663 Query: 316 PKEDARERAEQA-SKPALT------LEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 +D +Q+ KPA ++ TS + +L Y +P+ D LP + GK+ Sbjct: 664 GNKDGTPHNQQSLPKPAFAQCPPDLVKYATSSLQQRLPSYMVPSVWLGIDFLPMSVSGKL 723 Query: 157 N 155 + Sbjct: 724 D 724 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Frame = -2 Query: 619 VGELCIKSPSLFKEYWKRPEVTAESF----IDG-------GFFKTGDTVTVDEDGYFIIL 473 VGELCI++PSL + Y PE T SF +D ++TGD V DG L Sbjct: 3317 VGELCIEAPSLARCYLANPERTEYSFPSTVLDNWQTKKGTRVYRTGDLVRYASDGTLDFL 3376 Query: 472 GRTNADIMKVGGYKLSALEIE 410 GR + I K+ G ++ EIE Sbjct: 3377 GRKDGQI-KLRGQRIELGEIE 3396 Score = 42.7 bits (99), Expect = 0.001 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 11/84 (13%) Frame = -2 Query: 619 VGELCIKSPSLFKEYWKRPEVTAESFI-----------DGGFFKTGDTVTVDEDGYFIIL 473 VGEL I+ L + Y PE TAE FI + +KTGD V DG I + Sbjct: 2165 VGELIIEGSILCRGYLNDPERTAEVFIRSPSWLHDLRPNSTLYKTGDLVRYSADGKIIFI 2224 Query: 472 GRTNADIMKVGGYKLSALEIEAVL 401 GR + + K+ G + E+E L Sbjct: 2225 GRKDTQV-KMNGQRFELGEVEHAL 2247 Score = 31.6 bits (70), Expect = 2.6 Identities = 30/126 (23%), Positives = 52/126 (41%), Gaps = 34/126 (26%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFIDG-----GF-----------FKTGDTVTVDEDGY 485 GEL I+ P++ + Y +T+++FI G+ +KTGD V Sbjct: 4462 GELYIQGPTVARGYLHDDVLTSKAFIVDPQWLTGYKTNENQWSRRAYKTGDLVFWGPQSN 4521 Query: 484 FIILGRTNADIMKVGGYKLSALEIEAVLLEH------------------DTVLECAVLGL 359 + R ++ +K+ G ++ EIE V+ +H ++ AVLG+ Sbjct: 4522 LYYVRRKDSSQVKIRGQRVELAEIEEVIRQHIPPDVTVCVDLLSSDDQNTRIILGAVLGI 4581 Query: 358 PDEAYG 341 D A G Sbjct: 4582 GDRALG 4587
>ACSL1_CAVPO (Q9JID6) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) Length = 698 Score = 52.8 bits (125), Expect = 1e-06 Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 2/142 (1%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTE--TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 G VG P+P K++ + G GE+C+K P++FK Y K P TAE+ G+ Sbjct: 478 GHVGAPMPCNFIKLVDVEEMNYMAAMGEGEVCVKGPNVFKGYLKDPAKTAEALDKDGWLH 537 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +G I+ R G ++ +IE + + + V + V G E+ Sbjct: 538 TGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYVRSEPVAQVFVHG---ESLQ 594 Query: 340 EVICAIIVPKEDARERAEQASK 275 + AI+VP DA A A K Sbjct: 595 AFLIAIVVP--DAESLASWARK 614
>MENE_ECOLI (P37353) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 451 Score = 52.4 bits (124), Expect = 1e-06 Identities = 43/170 (25%), Positives = 81/170 (47%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDT 509 VG PLP E KI+ + E+ +++ S+ + YW+ ++ + D G++ T D Sbjct: 289 VGSPLPGREVKIVNN----------EVWLRAASMAEGYWRNGQLVS-LVNDEGWYATRDR 337 Query: 508 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 329 + +G I+GR + ++ GG + E+E V+ H VL+ ++ + D+ +G Sbjct: 338 GEM-HNGKLTIVGRLD-NLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGHRPV 395 Query: 328 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 A++ ++ + L+ W KDKLA ++ P R W +LP Sbjct: 396 AVMEYDHESVD--------------LSEWVKDKLARFQQPVR---WLTLP 428
>DLTA_STAEQ (Q5HQN0) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 52.4 bits (124), Expect = 1e-06 Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 5/159 (3%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAE--SFIDG-GFFKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K E TA +F DG + TGD + EDG + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNEEKTAAVFNFEDGVRTYHTGDKAKI-EDGLWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI--IVPKEDARERAEQASKP 272 + GY++ EIE L + V E V +P G+V+ I +VP E + ++ Sbjct: 386 LNGYRMELEEIETQLRQSKHVREAVV--VPVYKNGKVVHLIGAVVPTESVEDNLAMTTQI 443 Query: 271 ALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 L K +L Y IP + + LP GK++ Sbjct: 444 KHEL-------KSRLPEYMIPRKFEWMERLPLTLNGKLD 475
>DLTA_STAHJ (Q4L4U5) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 52.0 bits (123), Expect = 2e-06 Identities = 46/157 (29%), Positives = 72/157 (45%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAE--SFIDG-GFFKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL IK S+ Y E T +F DG + TGD +++DG + I GR + I K Sbjct: 328 GELVIKGNSVSLGYLDNKEKTDAVFNFEDGLRIYHTGDKA-IEKDGQWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ EIE L + + V E V+ + + +VP E+ R+ E + Sbjct: 386 LNGYRMELEEIETQLRQSEFVRETVVVPVYKNNKVIHLIGAVVPTEEVRDDLEMTRQ--- 442 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + S K +L Y IP + LP + GK++ Sbjct: 443 ----IKSELKSRLPEYMIPRKFVWMKQLPLTSNGKLD 475
>LCF3_YEAST (P39002) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (Fatty acid activator 3) Length = 694 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 2/129 (1%) Frame = -2 Query: 694 GTVGKPLPRVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 G VG + V AK++ D G K+ GEL +K + EY+K P TA SF G+F+ Sbjct: 472 GIVGDLVGSVTAKLVDVKDLGYYAKNNQGELLLKGAPVCSEYYKNPIETAVSFTYDGWFR 531 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD V G I+ R + + G ++ ++E+V + V V DE+ Sbjct: 532 TGDIVEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYA--DESRV 589 Query: 340 EVICAIIVP 314 + + I+VP Sbjct: 590 KPV-GIVVP 597
>ACSL1_HUMAN (P33121) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Acyl-CoA synthetase 1) (ACS1) (Pa Length = 698 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 2/129 (1%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTE--TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 G VG P+P K++ + +G GE+C+K P++F+ Y K P TAE+ G+ Sbjct: 478 GHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLH 537 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +G I+ R G ++ +IE + + + V + V G E+ Sbjct: 538 TGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFVHG---ESLQ 594 Query: 340 EVICAIIVP 314 + AI+VP Sbjct: 595 AFLIAIVVP 603
>LCF4_YEAST (P47912) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (Fatty acid activator 4) Length = 694 Score = 51.2 bits (121), Expect = 3e-06 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = -2 Query: 694 GTVGKPLPRVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 G G + + AK++ D G K+ GEL K + EY+K PE TA +F D G+F+ Sbjct: 472 GIAGDLVGTITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKNPEETAAAFTDDGWFR 531 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAV 404 TGD G I+ R + + G ++ ++E++ Sbjct: 532 TGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESI 570
>ACSL6_RAT (P33124) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) (Long-chain-fatty-acid--CoA ligase, brain isozyme) Length = 697 Score = 51.2 bits (121), Expect = 3e-06 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 4/131 (3%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTE----TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 G VG PLP K++ D E T G GE+C+K P++FK Y K + T E+ G+ Sbjct: 478 GHVGAPLPCNHIKLV--DAEELNYWTSKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGW 535 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +G I+ R G ++ +IE + + + V + V G +A Sbjct: 536 LHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKA 595 Query: 346 YGEVICAIIVP 314 + + I+VP Sbjct: 596 F---LVGIVVP 603
>AAS_SALTI (Q8Z406) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 9/153 (5%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------T 554 A K GTVG+ LP ++A+++ G E G L +K P++ Y + +P V Sbjct: 527 AAKPGTVGRILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLRVEKPGVLEVPSAEN 583 Query: 553 AESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 A + G++ TGD V DE+G+ I GR K+ G +S +E + L Sbjct: 584 ARGETERGWYDTGDIVRFDENGFVQIQGRAKR-FAKIAGEMVSLEMVEQLALGVSAEKMH 642 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARERAEQASK 275 A D + GE + E RE+ + ++ Sbjct: 643 ATAIKSDASKGEALVLFTTDSELTREKLQHYAR 675
>DLTA_LISMF (Q721J2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/157 (26%), Positives = 74/157 (47%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GE+ + S+ K Y PE T + F D G+ ++TGD+ + +DGY GR + I K Sbjct: 352 GEIVLIGASVSKGYLNEPEKTDQVFFDYKGYQAYRTGDSGII-KDGYLFFQGRLDFQI-K 409 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ +IE L + + CA++ + +++ A ++P E+ Q S Sbjct: 410 LHGYRIELEDIENNLKKVSYIQNCAIIPKMKDEKVDMLVAQVIPTNHDFEKEYQLS---- 465 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 A+ + K+ + Y IP + P GK++ Sbjct: 466 --AAIKNELKEFMPAYMIPRKWIYKTEFPLTMNGKID 500
>DLTA_STAES (Q8CT93) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 51.2 bits (121), Expect = 3e-06 Identities = 50/159 (31%), Positives = 72/159 (45%), Gaps = 5/159 (3%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAE--SFIDG-GFFKTGDTVTVDEDGYFIILGRTNADIMK 446 GEL I+ S+ Y K E T +F DG + TGD + EDG + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNEEKTTAVFNFEDGVRTYHTGDKAKI-EDGLWFIQGRIDFQI-K 385 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI--IVPKEDARERAEQASKP 272 + GY++ EIE L + V E V +P G+VI I +VP E + + Sbjct: 386 LNGYRMELEEIETQLRQSKHVREAVV--VPVYKNGKVIHLIGAVVPTEPVEDNLAMTTHI 443 Query: 271 ALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 L K +L Y IP + + LP + GK++ Sbjct: 444 KHEL-------KSRLPEYMIPRKFEWMEQLPLTSNGKLD 475
>DLTA_LISIN (Q92D47) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 50.8 bits (120), Expect = 4e-06 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GE+ + S+ K Y PE T + F D G+ + TGD+ + +DGY GR + I K Sbjct: 352 GEIILIGASVSKGYLNEPEKTDQVFFDYKGYQAYHTGDSGVI-KDGYLFFQGRLDFQI-K 409 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ +IE L + + CA++ + +++ A ++P E+ Q S Sbjct: 410 LHGYRIELEDIENNLKKVSYIQNCAIIPKMKDEKVDMLVAQVIPSSHDFEKEYQLS---- 465 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 A+ + K+ + Y IP + P GK++ Sbjct: 466 --AAIKNELKEFMPAYMIPRKWIYKTEFPLTMNGKID 500
>AAS_SALPA (Q5PEN7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 50.8 bits (120), Expect = 4e-06 Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 9/153 (5%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------T 554 A K GTVG+ LP ++A+++ G E G L +K P++ Y + +P V Sbjct: 527 AAKPGTVGRILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLRVEKPGVLEVPSAEN 583 Query: 553 AESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 A + G++ TGD V DE+G+ I GR K+ G +S +E + L Sbjct: 584 ARGETERGWYDTGDIVRFDENGFVQIQGRAKR-FAKIAGEMVSLEMVEQLALGVSADKMH 642 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARERAEQASK 275 A D + GE + E RE+ + ++ Sbjct: 643 ATAIKSDASKGEALVLFTTDSELTREKLQHYAR 675
>ACSL1_MOUSE (P41216) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) Length = 699 Score = 50.8 bits (120), Expect = 4e-06 Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 2/136 (1%) Frame = -2 Query: 715 LHGARKEGTVGKPLPRVEAKIIMDDGTE--TKDGVGELCIKSPSLFKEYWKRPEVTAESF 542 L G G VG P+P K++ + G GE+C+K ++FK Y K P TAE+ Sbjct: 472 LPGDWTAGHVGAPMPCNYVKLVDVEEMNYLASKGEGEVCVKGANVFKGYLKDPARTAEAL 531 Query: 541 IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 G+ TGD +G I+ R G ++ +IE + L + V + V G Sbjct: 532 DKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHG 591 Query: 361 LPDEAYGEVICAIIVP 314 E+ + A++VP Sbjct: 592 ---ESLQAFLIAVVVP 604
>DLTA_LISMO (Q8Y8D4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 50.4 bits (119), Expect = 5e-06 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 3/157 (1%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FKTGDTVTVDEDGYFIILGRTNADIMK 446 GE+ + S+ K Y PE T + F D G+ ++TGD+ + +DGY GR + I K Sbjct: 352 GEIVLIGASVSKGYLNEPEKTDQVFFDYKGYQAYRTGDSGII-KDGYLFFQGRLDFQI-K 409 Query: 445 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 266 + GY++ +IE L + + CA++ + +++ A ++P E+ Q S Sbjct: 410 LHGYRIELEDIENNLKKVSYIQNCAIIPKMKDEKVDMLVAQVIPTTHDFEKEYQLS---- 465 Query: 265 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 A+ K+ + Y IP + P GK++ Sbjct: 466 --AAIKKELKEFMPAYMIPRKWIYKTDFPLTMNGKID 500
>ACSL6_MOUSE (Q91WC3) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 50.1 bits (118), Expect = 7e-06 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 4/131 (3%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTE----TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 G VG PLP K++ D E T G GE+C+K P++FK Y K + T E+ G+ Sbjct: 478 GHVGAPLPCNHIKLV--DAEELNYWTCKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGW 535 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD +G I+ R G ++ +IE + + + V + V G +A Sbjct: 536 LHTGDIGKWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKA 595 Query: 346 YGEVICAIIVP 314 + + I+VP Sbjct: 596 F---LVGIVVP 603
>AAS_SALTY (Q8ZMA4) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 49.7 bits (117), Expect = 9e-06 Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 9/153 (5%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------T 554 A K GTVG+ LP ++A+++ G E G L +K P++ Y + +P V Sbjct: 527 AAKPGTVGRILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLRVEKPGVLEVPSAEN 583 Query: 553 AESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 + + G++ TGD V DE+G+ I GR K+ G +S +E + L Sbjct: 584 SRGETERGWYDTGDIVRFDENGFVQIQGRAKR-FAKIAGEMVSLEMVEQLALGVSADKMH 642 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARERAEQASK 275 A D + GE + E RE+ + ++ Sbjct: 643 ATAIKSDASKGEALVLFTTDSELTREKLQHYAR 675
>ACSL5_HUMAN (Q9ULC5) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 49.7 bits (117), Expect = 9e-06 Identities = 41/139 (29%), Positives = 61/139 (43%), Gaps = 2/139 (1%) Frame = -2 Query: 715 LHGARKEGTVGKPLP--RVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESF 542 L G G VG PL V+ + + D T + GE+CIK ++FK Y K PE T E+ Sbjct: 456 LPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEAL 515 Query: 541 IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 362 G+ TGD +G I+ R G ++ +IE + VL+ V G Sbjct: 516 DSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHG 575 Query: 361 LPDEAYGEVICAIIVPKED 305 E+ + ++VP D Sbjct: 576 ---ESLRSSLVGVVVPDTD 591
>ACVS_STRCL (Q01757) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) (Fragment) Length = 805 Score = 48.9 bits (115), Expect = 2e-05 Identities = 47/200 (23%), Positives = 85/200 (42%), Gaps = 17/200 (8%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 R + ++G+P+ V+ ++ D G +GEL I + Y R ++TAE F+ + Sbjct: 583 RADRSIGRPVRNVKWYVLSQDLKRLPVGAIGELYIGGCGVAPGYLNRDDLTAERFLTNPY 642 Query: 526 --------------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 ++TGD + G +GR++ + K+ G ++ EIEA E+ Sbjct: 643 ASEQDRARGTNARIYRTGDLARMLPSGEVEFMGRSDFQL-KLNGVRVEPGEIEAQATEYA 701 Query: 388 TVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA--LTLEALTSWSKDKLAPYK 215 V +C V+ G D ++P +T L S+ + +L Sbjct: 702 GVRKCVVIAREGAGGGS----------DRHLVGYYLTEPGAGVTEAELLSFLERRLIRIM 751 Query: 214 IPTRLHLWDSLPRNAMGKVN 155 +P R+ +S+P N GKV+ Sbjct: 752 VPARMVRLESIPVNVNGKVD 771
>FAD28_MYCBO (Q02278) Putative fatty-acid--CoA ligase fadD28 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 580 Score = 48.9 bits (115), Expect = 2e-05 Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 14/153 (9%) Frame = -2 Query: 724 SNPLHGARKEGTVGKPLPRVEAKIIMDDGT--ETKDG-VGELCIKSPSLFKEYWKRPEVT 554 + P G + LPR I+D T E DG VGE+ + ++ YW++P+ + Sbjct: 362 AKPCAGGGATSLISYMLPRSPIVRIVDSDTCIECPDGTVGEIWVHGDNVANGYWQKPDES 421 Query: 553 AESF-----------IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEA 407 +F +G + +TGD+ V DG I+GR D++ V G S +IEA Sbjct: 422 ERTFGGKIVTPSPGTPEGPWLRTGDSGFV-TDGKMFIIGRIK-DLLIVYGRNHSPDDIEA 479 Query: 406 VLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE 308 + E T CA + +P + E + AII K+ Sbjct: 480 TIQE-ITRGRCAAISVPGDRSTEKLVAIIELKK 511
>DLTA_STRA5 (P59591) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 48.5 bits (114), Expect = 2e-05 Identities = 45/172 (26%), Positives = 80/172 (46%), Gaps = 5/172 (2%) Frame = -2 Query: 655 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDG 488 +I ++G + +G GE+ I P++ K Y PE TAE+F + TGD ++ ++G Sbjct: 334 VIDEEGHKLPNGEQGEIIIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEG 393 Query: 487 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 311 + GR + I K GY++ ++ L + V AV + + + A IV K Sbjct: 394 LLLYGGRMDFQI-KFNGYRIELEDVSQNLNKSQYVKSAVAVPRYNKDHKVQNLLAYIVLK 452 Query: 310 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 E R+ E + +A+ KD + Y +P++ + LP GK++ Sbjct: 453 EGVRDDFE---RDLDLTKAIKEDLKDIMMDYMMPSKFIYREDLPLTPNGKID 501
>DLTA_STRA3 (Q8VM67) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 48.5 bits (114), Expect = 2e-05 Identities = 45/172 (26%), Positives = 80/172 (46%), Gaps = 5/172 (2%) Frame = -2 Query: 655 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDG 488 +I ++G + +G GE+ I P++ K Y PE TAE+F + TGD ++ ++G Sbjct: 334 VIDEEGHKLPNGEQGEIIIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEG 393 Query: 487 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 311 + GR + I K GY++ ++ L + V AV + + + A IV K Sbjct: 394 LLLYGGRMDFQI-KFNGYRIELEDVSQNLNKSQYVKSAVAVPRYNKDHKVQNLLAYIVLK 452 Query: 310 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 E R+ E + +A+ KD + Y +P++ + LP GK++ Sbjct: 453 EGVRDDFE---RDLDLTKAIKEDLKDIMMDYMMPSKFIYREDLPLTPNGKID 501
>HMWP2_YEREN (P48633) High-molecular-weight protein 2 (HMWP2)| Length = 2035 Score = 48.1 bits (113), Expect = 3e-05 Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 4/132 (3%) Frame = -2 Query: 685 GKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKT 518 G PL +++ + G + D V GEL I + + Y+ + + F+ D +++T Sbjct: 882 GFPLTNQRYRVVDERGRDCPDWVSGELWIGGIGVAEGYFNDSLRSEQQFLTLPDERWYRT 941 Query: 517 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 338 GD DG LGR + + KVGGY++ EIE+ L + V + VL + ++ + Sbjct: 942 GDLGCYWPDGTIEFLGRRDKQV-KVGGYRIELGEIESALSQLAGVKQATVLAIGEKE--K 998 Query: 337 VICAIIVPKEDA 302 + A +VP+ +A Sbjct: 999 TLAAYVVPQSEA 1010
>DLTA_STRMU (Q53526) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 47.8 bits (112), Expect = 4e-05 Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 5/183 (2%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG---GFFK 521 +G P II + G + +G GE+ + P++ K Y PE TA +F + + Sbjct: 327 IGYTKPDSPTFIIDESGHKLANGQQGEIIVSGPAVSKGYLNNPERTAAAFFEFEGLPAYH 386 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAY 344 TGD ++ ++G + GR + I K GY++ E+ L + + AV + Sbjct: 387 TGDLGSMTDEGLLLYGGRMDFQI-KFNGYRIELEEVSQNLNKSQYIASAVAVPRYNKDHK 445 Query: 343 GEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMG 164 + + A +V K+ E+ E+A +A+ + +D + Y +P++ LP G Sbjct: 446 VQNLLAYVVLKDGVEEQFERALD---ITKAIKADLQDVMMDYMMPSKFLYRKDLPLTPNG 502 Query: 163 KVN 155 K++ Sbjct: 503 KID 505
>LCF2_YEAST (P39518) Long-chain-fatty-acid--CoA ligase 2 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 2) (Fatty acid activator 2) Length = 744 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 1/135 (0%) Frame = -2 Query: 628 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 449 KD GEL I+ P +F+ Y+K P T+++ G+F TGD +D G ++ R Sbjct: 536 KDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRISVIDRVKNFFK 595 Query: 448 KVGGYKLSALEIEAVLLEH-DTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKP 272 G ++ +IE + L + + V G P + + + I+ DA + A P Sbjct: 596 LAHGEYIAPEKIENIYLSSCPYITQIFVFGDPLKTF---LVGIVGVDVDAAQPILAAKHP 652 Query: 271 ALTLEALTSWSKDKL 227 + +W+K+ L Sbjct: 653 -----EVKTWTKEVL 662
>ACVS_EMENI (P27742) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3770 Score = 47.8 bits (112), Expect = 4e-05 Identities = 52/206 (25%), Positives = 86/206 (41%), Gaps = 18/206 (8%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESF 542 P R + ++G+ + + ++ D G VGEL + + + Y RPEVTAE F Sbjct: 1719 PFPERRTDKSIGQQIGNSTSYVLNADMKRVPIGAVGELYLGGEGVARGYHNRPEVTAERF 1778 Query: 541 IDGGF--------------FKTGDTV--TVDEDGYFIILGRTNADIMKVGGYKLSALEIE 410 + F ++TGD V +G LGR + + K+ G ++ EIE Sbjct: 1779 LRNPFQTDSERQNGRNSRLYRTGDLVRWIPGSNGEIEYLGRNDFQV-KIRGLRIELGEIE 1837 Query: 409 AVLLEHDTVLECAVLGLP-DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKD 233 AV+ H + + V+ E + + V AS P L+ A+ + + Sbjct: 1838 AVMSSHPDIKQSVVIAKSGKEGDQKFLVGYFV-----------ASSP-LSPGAIRRFMQS 1885 Query: 232 KLAPYKIPTRLHLWDSLPRNAMGKVN 155 +L Y IP+ SLP GK++ Sbjct: 1886 RLPGYMIPSSFIPISSLPVTPSGKLD 1911 Score = 47.4 bits (111), Expect = 5e-05 Identities = 56/219 (25%), Positives = 86/219 (39%), Gaps = 18/219 (8%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGG 530 AR ++G+P+ V+ I+ G GEL I + K Y RP++T + FI Sbjct: 636 ARNNTSLGRPVRNVKCYILNKSLKRVPIGATGELHIGGLGISKGYLNRPDLTPQRFIPNP 695 Query: 529 F--------------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEH 392 F +KTGD +G LGR + I K+ G ++ EIE+ L + Sbjct: 696 FQTDHEKELGLNQLMYKTGDLARWLPNGEIEYLGRADFQI-KLRGIRIEPGEIESTLAGY 754 Query: 391 DTVLECAVLGLPDEAYGEVICAIIVPKEDARERA---EQASKPALTLEALTSWSKDKLAP 221 V V+ +GE KE E +++ AL + + KL Sbjct: 755 PGVRTSLVVS-KRLRHGE--------KETTNEHLVGYYVGDNTSVSETALLQFLELKLPR 805 Query: 220 YKIPTRLHLWDSLPRNAMGKVNXXXXXXXXEV*PRLH*C 104 Y IPTRL +P GK + + P++ C Sbjct: 806 YMIPTRLVRVSQIPVTVNGKADLRALPSVDLIQPKVSSC 844 Score = 42.4 bits (98), Expect = 0.001 Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 21/178 (11%) Frame = -2 Query: 625 DGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDG 488 + VGEL + + + Y +P +T + FI F ++TGD D Sbjct: 2829 NAVGELYLAGDCVARGYLNQPVLTGDRFIQNPFQTEQDIACGSYPRLYRTGDLFRCRLDR 2888 Query: 487 ----YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD--EAYGEVICA 326 Y LGR + + K+ GY++ E++ VL V ECAV+ + +AY + Sbjct: 2889 QHQPYLEYLGRADLQV-KIRGYRIEPSEVQNVLASCPGVRECAVVAKYENTDAYSRIAKF 2947 Query: 325 IIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL-HLWDSLPRNAMGKVN 155 ++ E +S + + K KL Y +P L L LP GK++ Sbjct: 2948 LVGYYTPDTETVSDSS--------ILAHMKSKLPAYMVPKYLCRLEGGLPVTINGKLD 2997
>ORA_PLAFN (P16405) Octapeptide-repeat antigen (ORA) (Fragment)| Length = 701 Score = 47.8 bits (112), Expect = 4e-05 Identities = 22/51 (43%), Positives = 32/51 (62%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRT 464 GEL IKS S+F Y+ E T +F + G+FKTGD V ++++G L R+ Sbjct: 436 GELLIKSDSMFSGYFLEKESTEHAFTNDGYFKTGDIVQINDNGSLTFLDRS 486
>ACSL6_HUMAN (Q9UKU0) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 47.4 bits (111), Expect = 5e-05 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Frame = -2 Query: 694 GTVGKPLPRVEAKIIMDDGTETK----DGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 G VG PLP K++ D E G GE+C++ P++FK Y K P+ T E+ G+ Sbjct: 478 GHVGAPLPCNHIKLV--DVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGW 535 Query: 526 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 347 TGD G I+ R G ++ +IE + + V + V G +A Sbjct: 536 LHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKA 595 Query: 346 YGEVICAIIVP 314 + + I+VP Sbjct: 596 F---LVGIVVP 603
>ACVS_CEPAC (P25464) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3712 Score = 46.6 bits (109), Expect = 8e-05 Identities = 50/208 (24%), Positives = 85/208 (40%), Gaps = 20/208 (9%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESF 542 P R + ++G L + ++ DD G VGEL + + + Y RP++TA+ F Sbjct: 1667 PFPERRTDKSIGCQLDNSTSYVLNDDMKRVPIGAVGELYLGGDGVARGYHNRPDLTADRF 1726 Query: 541 IDGGF--------------FKTGDTV----TVDEDGYFIILGRTNADIMKVGGYKLSALE 416 F +KTGD V + DG LGR + + K+ G ++ E Sbjct: 1727 PANPFQTEQERLEGRNARLYKTGDLVRWIHNANGDGEIEYLGRNDFQV-KIRGQRIELGE 1785 Query: 415 IEAVLLEHDTVLECAVLGLPDEAYGE-VICAIIVPKEDARERAEQASKPALTLEALTSWS 239 IEAVL + + + VL + G+ + V +S +L+ +A+ + Sbjct: 1786 IEAVLSSYPGIKQSVVLAKDRKNDGQKYLVGYFV-----------SSAGSLSAQAIRRFM 1834 Query: 238 KDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 L Y +P +L P GK++ Sbjct: 1835 LTSLPDYMVPAQLVPIAKFPVTVSGKLD 1862 Score = 44.3 bits (103), Expect = 4e-04 Identities = 51/209 (24%), Positives = 83/209 (39%), Gaps = 26/209 (12%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF 527 RK+ ++G+P+ V+ I+ + GV GEL I + + Y R E+T + F+ + Sbjct: 580 RKDMSLGRPVRNVKCYILDANLKRVPIGVTGELHIGGLGISRGYMNREELTRQKFLPNPY 639 Query: 526 --------------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 389 +KTGD G LGR + I K+ G ++ EIE+ L + Sbjct: 640 QTDKERQRGVNSTMYKTGDLARWLPSGEVEYLGRADFQI-KLRGIRIEPGEIESTLAMYP 698 Query: 388 TVLECAVLG----------LPDEAYGEVICAI-IVPKEDARERAEQASKPALTLEALTSW 242 + V+ + D G +C +P+ D L S+ Sbjct: 699 GIRASIVVSKKLLSQGQETIQDHLVGYYVCDEGHIPEGD-----------------LLSF 741 Query: 241 SKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 + KL Y +PTRL +P N GK + Sbjct: 742 LEKKLPRYMVPTRLVQLAQIPTNINGKAD 770
>AAS_ERWCT (Q6D107) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 738 Score = 46.6 bits (109), Expect = 8e-05 Identities = 38/146 (26%), Positives = 65/146 (44%), Gaps = 9/146 (6%) Frame = -2 Query: 706 ARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------T 554 A K +VG LP +E+++I G G L ++ P++ K Y + P V Sbjct: 527 ATKIHSVGLLLPEMESRLITVPGITRG---GRLQLRGPNIMKGYLRVENPGVLETPAAEN 583 Query: 553 AESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 374 AE + G++ TGD V +DE G+ I+GR K+ G +S +E + ++ + Sbjct: 584 AEGELQQGWYDTGDIVELDERGFCTIIGRVKR-FAKLAGEMVSLESVEQLAVKVSPEAQH 642 Query: 373 AVLGLPDEAYGEVICAIIVPKEDARE 296 A D + GE + + R+ Sbjct: 643 AASAKSDSSKGEALVLFTTDSQITRD 668
>MENE_SALTY (P37418) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 455 Score = 46.2 bits (108), Expect = 1e-04 Identities = 45/170 (26%), Positives = 78/170 (45%) Frame = -2 Query: 688 VGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDT 509 VG PLP E +I+ + E+ +++ S+ + YW+ ++ D G+F T D Sbjct: 289 VGAPLPGREIRIVDN----------EVWLRAASMAEGYWRDGKLIP-LVNDEGWFATRDR 337 Query: 508 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 329 ++ G I GR + ++ GG + E+E V+ H V + V+ + D+ +G Sbjct: 338 GELNH-GRLTIAGRLD-NLFFSGGEGIQPEEVERVINAHPLVQQAFVVPVEDKEFGHRPV 395 Query: 328 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 179 A++ E A QA L W +DKLA ++ P R W ++P Sbjct: 396 AVV-------EYASQAGDVNLA-----EWVRDKLARFQQPVR---WLTMP 430
>MENE_HAEIN (P44565) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 452 Score = 46.2 bits (108), Expect = 1e-04 Identities = 46/165 (27%), Positives = 83/165 (50%) Frame = -2 Query: 703 RKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFF 524 RK+G VG+PL E ++ D E+ +K L YWK ++ + + G+ Sbjct: 279 RKQG-VGQPLLGREYCLVND----------EIWLKGAGLAMGYWKDRQIVPLTN-NQGWI 326 Query: 523 KTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAY 344 +T D + ++G +I+GR + ++ GG + EIE V+++H +V + VL ++ + Sbjct: 327 QTKDK-GIWQEGELVIIGRLD-NMFISGGENIQPEEIEQVIIQHSSVNQVFVLPQKNKEF 384 Query: 343 GEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIP 209 G+ A++ + E SK A +E L + +DKLA +K P Sbjct: 385 GQRPVALV-------DFNEPFSKSA--VENLMFFLQDKLARFKQP 420
>LYS2_ASHGO (Q75BB3) L-aminoadipate-semialdehyde dehydrogenase large subunit (EC| 1.2.1.31) (Alpha-aminoadipate reductase) (Alpha-AR) Length = 1385 Score = 45.8 bits (107), Expect = 1e-04 Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 44/199 (22%) Frame = -2 Query: 619 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----------------------------F 524 VGE+ +++ L + Y PE+ E FID F + Sbjct: 619 VGEIYVRAGGLSEGYRGLPEINKEKFIDNWFVDAGHWGGLDLSGDEPWRNYWLGVRDRLY 678 Query: 523 KTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAY 344 +TGD +G GR + D +K+ G+++ EI+ + ++ E L D+ Sbjct: 679 RTGDLGRYLPNGDCECCGRAD-DQVKIRGFRIELGEIDTNISQYPLCRENITLLRKDQNG 737 Query: 343 GEVICAIIVPKEDARERAE--QASKPALTLEALTS--------------WSKDKLAPYKI 212 + + +VP+ D + A A ++ E++ + K +LA Y I Sbjct: 738 ESTLISYLVPRSDQKALASFISAVPESIATESIAGSLIKYHKLINDIRGFLKKRLAGYAI 797 Query: 211 PTRLHLWDSLPRNAMGKVN 155 PT + + + LP N GK++ Sbjct: 798 PTLIMVMERLPLNPNGKID 816
>PCL_ECTHA (P42516) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) (Fragment) Length = 391 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/100 (32%), Positives = 46/100 (46%) Frame = -2 Query: 457 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 278 DI+++GG +S + L H+ V CAV E + A IVP A + Sbjct: 299 DIIQIGGVNVSPGHVARRLESHEAVAACAVRS-HGEGSRRRLKAFIVP-------ARSDA 350 Query: 277 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 P + L +W + L + PT L + LPRNAMGK+ Sbjct: 351 DPETLRQTLENWIWEHLPAVERPTDLRIGTELPRNAMGKL 390
>VRAA_STAHJ (Q4L3Q0) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 461 Score = 45.8 bits (107), Expect = 1e-04 Identities = 42/178 (23%), Positives = 76/178 (42%) Frame = -2 Query: 691 TVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGD 512 +VG+ P V K+ D + +G L ++S ++ Y V S+I+ TGD Sbjct: 291 SVGQVFPNVSIKLEAQDNRK----IGLLKVQSNMIYSGYVDVGVVQPHSWIE-----TGD 341 Query: 511 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 332 + + +++ ++ D + +GG + IE + D + E V+G P +GE+ Sbjct: 342 YAYIQNNQLYLVSRKS--DRLIIGGKNIYPNVIEQQVKSLDGIEEAVVVGEPHRRFGEIA 399 Query: 331 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 158 I V ++ L L + + L+ Y+IP++L LP GKV Sbjct: 400 VLIYVGNQE------------LDYTTLRRYLRQTLSRYEIPSKLVRVKDLPFTNSGKV 445
>ACSL5_MOUSE (Q8JZR0) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = -2 Query: 694 GTVGKPLPR--VEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 G VG P+ V+ + + D + + GE+CIK ++FK Y K PE T E G+ Sbjct: 463 GHVGTPVACNFVKLEDVADMNYFSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLH 522 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +G I+ R G ++ +IE V VL+ V G E+ Sbjct: 523 TGDIGRWLPNGTLKIVDRKKNIFKLAQGEYIAPEKIENVYSRSRPVLQVFVHG---ESLR 579 Query: 340 EVICAIIVPKEDA 302 + ++VP D+ Sbjct: 580 SFLIGVVVPDPDS 592
>LCF1_SCHPO (O60135) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 676 Score = 43.9 bits (102), Expect = 5e-04 Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 4/134 (2%) Frame = -2 Query: 697 EGTVGKPLPRVEAKII-MDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGG 530 + + G LP E K++ ++G G GE+ ++ PSL + Y R + ESF G Sbjct: 453 DDSAGSLLPCTEMKLVDCEEGNYNSHGHPPRGEIWLRGPSLTRGYLNRDKENKESFTPDG 512 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 350 +F+TGD + +G I+ R + G ++ ++E+ V V D+ Sbjct: 513 WFRTGDVGELTPEGLLRIIDRKKNLVKTQNGEYIALEKLESRYRTSSLVSNICVYA--DQ 570 Query: 349 AYGEVICAIIVPKE 308 + + AIIVP E Sbjct: 571 TKVKPL-AIIVPNE 583
>ENTF_SHIFL (P29698) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1281 Score = 43.5 bits (101), Expect = 7e-04 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 455 G+L + L + Y RP++TA FI F ++TGD ++G LGR++ D Sbjct: 804 GDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRSD-D 862 Query: 454 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARE----RAE 287 +K+ G ++ EI+ V+ V + + VI DAR+ Sbjct: 863 QLKIRGQRIELGEIDRVMQALPDVKQAV-------THACVINQAAATGGDARQLVGYLVS 915 Query: 286 QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 Q+ P L AL + ++ L P+ +P L LP +A GK++ Sbjct: 916 QSGLP-LDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLD 958
>LCF1_YEAST (P30624) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 700 Score = 43.5 bits (101), Expect = 7e-04 Identities = 24/91 (26%), Positives = 46/91 (50%) Frame = -2 Query: 640 GTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 461 G K+ GE+ I ++ EY+K E T+++ G+FKTGD + +G+ I+ R Sbjct: 496 GYFAKNNQGEVWITGANVTPEYYKNEEETSQALTSDGWFKTGDIGEWEANGHLKIIDRKK 555 Query: 460 ADIMKVGGYKLSALEIEAVLLEHDTVLECAV 368 + + G ++ ++E+V ++ V V Sbjct: 556 NLVKTMNGEYIALEKLESVYRSNEYVANICV 586
>ACSL5_RAT (O88813) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 43.5 bits (101), Expect = 7e-04 Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 2/133 (1%) Frame = -2 Query: 694 GTVGKPLPR--VEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 521 G VG P+ V+ + + D + + GE+CIK ++FK Y K PE T E G+ Sbjct: 463 GHVGTPVSCNFVKLEDVADMNYFSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLH 522 Query: 520 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 341 TGD +G I+ R G ++ +IE V +L+ V G E+ Sbjct: 523 TGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENVYSRSRPILQVFVHG---ESLR 579 Query: 340 EVICAIIVPKEDA 302 + ++VP ++ Sbjct: 580 SFLIGVVVPDPES 592
>ENTF_ECOLI (P11454) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 43.1 bits (100), Expect = 9e-04 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 455 G+L + L + Y RP++TA FI F ++TGD ++G LGR++ D Sbjct: 800 GDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRSD-D 858 Query: 454 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARE----RAE 287 +K+ G ++ EI+ V+ V + + VI DAR+ Sbjct: 859 QLKIRGQRIELGEIDRVMQALPDVEQAV-------THACVINQAAATGGDARQLVGYLVS 911 Query: 286 QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 Q+ P L AL + ++ L P+ +P L LP +A GK++ Sbjct: 912 QSGLP-LDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLD 954
>LYS2_CANAL (Q12572) L-aminoadipate-semialdehyde dehydrogenase large subunit (EC| 1.2.1.31) (Alpha-aminoadipate reductase) (Alpha-AR) Length = 1391 Score = 42.4 bits (98), Expect = 0.001 Identities = 45/204 (22%), Positives = 80/204 (39%), Gaps = 49/204 (24%) Frame = -2 Query: 619 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----------------------------- 527 VGE+ +++ L + Y P++ A FI + Sbjct: 614 VGEIYVRAAGLAEGYRGLPDLNAAKFITNWYVNPDKWIEQDEANKKSSETSERTWSVKPR 673 Query: 526 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 +++GD DG GR + D +K+ G+++ EI+ L +H V E L Sbjct: 674 DRMYRSGDLGRYFSDGNVECCGRAD-DQVKIRGFRIELGEIDTHLSQHPLVRENVTLVRR 732 Query: 355 DEAYGEVICAIIVPKEDARERA---------EQASKPALT--------LEALTSWSKDKL 227 D+ + + IVPK+ + ++++ P + ++ + + K KL Sbjct: 733 DKNEEPTLISYIVPKDSPELKTFFADVDFPLKKSNDPIVKGLVAYRELIKDIKGYLKKKL 792 Query: 226 APYKIPTRLHLWDSLPRNAMGKVN 155 A Y IPT + LP N GKV+ Sbjct: 793 ASYAIPTIIVPLVKLPLNPNGKVD 816
>AAS_PHOLL (Q7N7A9) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 639 Score = 42.0 bits (97), Expect = 0.002 Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 9/87 (10%) Frame = -2 Query: 700 KEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKR--------PEVTAE- 548 K GTVG+ LP +E ++I G K G G L ++ P++ K Y + P V E Sbjct: 529 KVGTVGRILPAMEFRLIPIAGI--KQG-GRLQLRGPNMMKGYLRMEDPNHLEPPAVKDEH 585 Query: 547 SFIDGGFFKTGDTVTVDEDGYFIILGR 467 I + TGD V++DE G+ ILGR Sbjct: 586 GNIQFDWLDTGDIVSIDEQGFCTILGR 612
>ENTF_ECO57 (Q8XBV9) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 41.6 bits (96), Expect = 0.003 Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%) Frame = -2 Query: 616 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 455 G+L + L + Y RP++TA FI F ++TGD ++G LGR++ D Sbjct: 800 GDLYLTGIQLAQGYLGRPDLTASRFIADPFVPGERMYRTGDVARWLDNGAVEYLGRSD-D 858 Query: 454 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARE----RAE 287 +K+ G ++ EI+ V+ V + + VI DAR+ Sbjct: 859 QLKIRGQRIELGEIDRVMQALPDVEQAV-------THACVINQAAATGGDARQLVGYLVS 911 Query: 286 QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 155 Q+ P L AL + ++ L P+ P L LP +A GK++ Sbjct: 912 QSGLP-LDTSALQAQLRETLPPHMAPVVLLQLPQLPLSANGKLD 954
>S27A3_MOUSE (O88561) Long-chain fatty acid transport protein 3 (EC 6.2.1.-)| (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3) Length = 667 Score = 40.4 bits (93), Expect = 0.006 Identities = 49/188 (26%), Positives = 73/188 (38%), Gaps = 9/188 (4%) Frame = -2 Query: 718 PLHGARKEGTVGKPLPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFI 539 P R + G+P+ + + E V + +SP F Y PE+ + + Sbjct: 440 PFSLIRYDVMTGEPIRNAQGHCMTTSPGEPGLLVAPVSQQSP--FLGYAGAPELAKDKLL 497 Query: 538 DGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLE 377 F F TGD + DE G+ RT D ++ G ++ E+ VL D + E Sbjct: 498 KDVFWSGDVFFNTGDLLVCDEQGFLHFHDRT-GDTIRWKGENVATTEVAEVLETLDFLQE 556 Query: 376 CAVLGLPDEAYGEVICAIIVPKEDARE-RAEQASKP--ALTLEALTSWSKDKLAPYKIPT 206 + G + VP + R A A +P AL L L S + L PY P Sbjct: 557 VNIYG------------VTVPGHEGRAGMAALALRPPQALNLVQLYSHVSENLPPYARPR 604 Query: 205 RLHLWDSL 182 L L +SL Sbjct: 605 FLRLQESL 612
>S27A5_MOUSE (Q4LDG0) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) Length = 689 Score = 39.3 bits (90), Expect = 0.012 Identities = 21/58 (36%), Positives = 32/58 (55%) Frame = -2 Query: 529 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 356 +F TGD +T+D++G+F R D + G +S E+E VL D + E V G+P Sbjct: 529 YFNTGDVLTLDQEGFFYFQDRL-GDTFRWKGENVSTGEVECVLSSLDFLEEVNVYGVP 585 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 99,539,170 Number of Sequences: 219361 Number of extensions: 2077872 Number of successful extensions: 6163 Number of sequences better than 10.0: 280 Number of HSP's better than 10.0 without gapping: 5513 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5768 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7479594804 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
