ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal7o13 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 249 bits (636), Expect = 5e-66 Identities = 118/144 (81%), Positives = 130/144 (90%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 ADVISLHPVLDKTT+HL+N E L MKK+A+L+N SRGPVIDE ALV+HL+ NPMFRVGL Sbjct: 237 ADVISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGL 296 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 273 DVFEDEPYMKPGLA+MKNA++VPHIASASKWTREGMATLAALNVLGKIKGYPVW +PN V Sbjct: 297 DVFEDEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRV 356 Query: 272 EPFLDEEATPPPACPSIVNAKQLG 201 EPFLDE +PP A PSIVNAK LG Sbjct: 357 EPFLDENVSPPAASPSIVNAKALG 380
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 105 bits (262), Expect = 1e-22 Identities = 54/110 (49%), Positives = 71/110 (64%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D ISLH L K TYH+I + L +MK A+L+N SRG V+D AL++ LK + GL Sbjct: 205 SDFISLHVPLTKETYHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGL 264 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE+EPY L ++KN V+ PHI SA+ REGMA L A N++ KG Sbjct: 265 DVFEEEPYYNEELFKLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKG 314
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 101 bits (252), Expect = 2e-21 Identities = 54/110 (49%), Positives = 71/110 (64%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D + L L + TYHLIN ERL +MKK A+L+N +RG V+D ALV+ LK + GL Sbjct: 205 SDFVVLAVPLTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAGL 264 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE+EPY L ++ N V+ PHI SAS REGMA L A N++ +G Sbjct: 265 DVFEEEPYYNEELFKLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRG 314
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 100 bits (249), Expect = 4e-21 Identities = 52/110 (47%), Positives = 71/110 (64%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D + L L+K TYH+IN ERL MMK+ A+L+N +RG VID AL++ LK + GL Sbjct: 206 SDFVVLAVPLNKETYHMINEERLKMMKRTAILINVARGKVIDTKALIKALKEGWIAGAGL 265 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DV+E+EPY L + N V+ PHI SA+ REGMA L A N++ +G Sbjct: 266 DVYEEEPYYNEELFSLDNVVLTPHIGSATFGAREGMAKLVAENLIAFKRG 315
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 95.5 bits (236), Expect = 1e-19 Identities = 50/105 (47%), Positives = 68/105 (64%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D + L L K T ++IN ERL +MKK A+LVN +RG V+D AL++ LK + GL Sbjct: 205 SDFVVLAVPLTKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGL 264 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 318 DV+E+EPY L +KN V+ PHI SA+ REGMA L A N++ Sbjct: 265 DVYEEEPYYNEELFSLKNVVLAPHIGSATYGAREGMAELVARNLI 309
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 90.5 bits (223), Expect = 4e-18 Identities = 49/110 (44%), Positives = 67/110 (60%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D + L L K T ++IN ERL +MK A+LVN +RG V+D AL++ LK + GL Sbjct: 205 SDFVILAVPLTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGL 264 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE+EPY L + N V+ PHI SA+ RE MA L A N++ +G Sbjct: 265 DVFEEEPYYNEELFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRG 314
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 87.8 bits (216), Expect = 2e-17 Identities = 48/111 (43%), Positives = 67/111 (60%), Gaps = 1/111 (0%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D + + L + T+H+I E+LA MK A+L+NA RGPV+DE AL+ LK + GL Sbjct: 200 SDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALKDKTIHAAGL 259 Query: 452 DVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE EP + L + N V +PHI SA+ TR GMA A N++ + G Sbjct: 260 DVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLIAALAG 310
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 87.4 bits (215), Expect = 3e-17 Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 1/111 (0%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ L+ + GL Sbjct: 201 SDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGL 260 Query: 452 DVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE EP + L M N V VPHI SA+ TR GMA A N++ ++G Sbjct: 261 DVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQG 311
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 87.4 bits (215), Expect = 3e-17 Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 1/111 (0%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ L+ + GL Sbjct: 201 SDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGL 260 Query: 452 DVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE EP + L M N V VPHI SA+ TR GMA A N++ ++G Sbjct: 261 DVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQG 311
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 84.3 bits (207), Expect = 3e-16 Identities = 48/112 (42%), Positives = 68/112 (60%), Gaps = 2/112 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D++S+H L T HLI L +MKK A+LVN RG ++D ALV+ L+ + L Sbjct: 206 SDILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAAL 265 Query: 452 DVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE+EP + P L KN V+ PH ASA++ TR MA +AA N++ +G Sbjct: 266 DVFEEEP-LNPNHPLTAFKNVVLAPHAASATRETRLRMAMMAAENLVAFAQG 316
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/104 (40%), Positives = 63/104 (60%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DV+SL+ L+ T H+I MK+ V+VN +RG V+DE ALVE L ++ GL Sbjct: 210 SDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSAGL 269 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 321 DVFE+EP + PGL E + +++PH+ + S T+ M +NV Sbjct: 270 DVFEEEPKIHPGLLENEKVILLPHLGTNSLETQYKMECAVLMNV 313
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 79.0 bits (193), Expect = 1e-14 Identities = 47/137 (34%), Positives = 72/137 (52%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D++S++ L+ T+HLIN E + MK V+VN +RG VIDE A+ + L++ + GL Sbjct: 218 SDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGL 277 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 273 DVFE EP + L M + +PH+ + S TR+ M L N K + G + Sbjct: 278 DVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVENA----KNVILTGKVLTI 333 Query: 272 EPFLDEEATPPPACPSI 222 P L E P + P + Sbjct: 334 VPELQNEDWPNESKPLV 350
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/110 (37%), Positives = 64/110 (58%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD I+LH L T H+I E++A+MKK A++VN +RG +IDE AL E LK + L Sbjct: 195 ADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRAAAL 254 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE+EP L + N + PH ++++ ++ T+ A + ++G Sbjct: 255 DVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVLRG 304
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 78.2 bits (191), Expect = 2e-14 Identities = 58/147 (39%), Positives = 78/147 (53%), Gaps = 3/147 (2%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD +SLH L T + N E + MKK L+N +RG VIDE ALV L A + + L Sbjct: 276 ADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAAL 335 Query: 452 DVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 DVF +EP K L + +N V PH+ +++K +EG+A A V G +KG NA Sbjct: 336 DVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGELSATAVNA 395 Query: 275 --VEPFLDEEATPPPACPSIVNAKQLG 201 V P + E T P IV A++LG Sbjct: 396 PMVAPEVLSELT-----PYIVLAEKLG 417
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 75.9 bits (185), Expect = 9e-14 Identities = 55/147 (37%), Positives = 79/147 (53%), Gaps = 3/147 (2%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D++++H L T HLI+ + +MK A +VN +RG +IDE AL LK + L Sbjct: 196 SDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALKDGEIAGAAL 255 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHI-ASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 DVFE+EP L E++N V+ PHI AS S+ R+ AA+ V +IK G P Sbjct: 256 DVFEEEPPEGSPLLELENVVLTPHIGASTSEAQRD-----AAIIVANEIKTVFQGGAPRN 310 Query: 275 V--EPFLDEEATPPPACPSIVNAKQLG 201 V P +D E T P I A+++G Sbjct: 311 VLNMPVMDSE-TYKSLKPYIELAEKMG 336
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 75.9 bits (185), Expect = 9e-14 Identities = 47/132 (35%), Positives = 68/132 (51%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+I++H L K T L+N E +A KK L+N +RG +IDE AL+E L+ + L Sbjct: 193 ADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENGHVAGAAL 252 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 273 DVFE EP + L + + PH+ +++K + +A + VL KG PV N Sbjct: 253 DVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKGLPVMSAINLP 312 Query: 272 EPFLDEEATPPP 237 DE A P Sbjct: 313 AMTKDEFAKIKP 324
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 75.1 bits (183), Expect = 2e-13 Identities = 43/111 (38%), Positives = 60/111 (54%), Gaps = 1/111 (0%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D I L L TYH+I +MK A+ VN SRG +DE AL+ L+ + GL Sbjct: 204 SDFILLITPLTDETYHMIGEREFKLMKNSAIFVNISRGKTVDEKALIRALQEGWIRGAGL 263 Query: 452 DVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DV+E EP + L ++ N ++PHI SA+ R M AA N+L I+G Sbjct: 264 DVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQG 314
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/94 (45%), Positives = 55/94 (58%), Gaps = 5/94 (5%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+++LH L +TT LIN E L+ MKK A L+N RGP+IDE+ALV+ LK + L Sbjct: 197 ADIVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGHLGGAAL 256 Query: 452 DVFEDEPYMKP-----GLAEMKNAVVVPHIASAS 366 DV EP K M N ++ PHIA AS Sbjct: 257 DVMVKEPPEKDNPLILAAKTMPNLIITPHIAWAS 290
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 73.6 bits (179), Expect = 5e-13 Identities = 43/125 (34%), Positives = 69/125 (55%), Gaps = 3/125 (2%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DVI++H K T LI + MK ++VNA+RG ++DE AL E +KA + L Sbjct: 194 SDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAALYEAIKAGKVAAAAL 253 Query: 452 DVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPN- 279 DV+E EP L ++ N V PHIA++++ + + + A +++ KG PV N Sbjct: 254 DVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIVNMAKGLPVRNAVNL 313 Query: 278 -AVEP 267 ++EP Sbjct: 314 PSIEP 318
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 72.8 bits (177), Expect = 8e-13 Identities = 42/115 (36%), Positives = 64/115 (55%), Gaps = 3/115 (2%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DVI+LH L T ++I E+L MK+ A+L+N +RG ++DE AL++ LK + G Sbjct: 193 SDVITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKDGTIGGAGF 252 Query: 452 DVFEDEPYMKPGL---AEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 297 DV EP + A++ N +V PH+A ASK + +A NV + G P Sbjct: 253 DVVAQEPPKDGNILCDADLPNLIVTPHVAWASKEAMQILADQLVDNVEAFVAGKP 307
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 70.1 bits (170), Expect = 5e-12 Identities = 40/112 (35%), Positives = 60/112 (53%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD I+LH T +LIN E LA MK A ++N SRG +IDE ALV ++ + L Sbjct: 222 ADFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETAQIGGAAL 281 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 297 DVF EP + L E N ++ PH+ ++++ + +A A + + G P Sbjct: 282 DVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLGLP 333
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/130 (33%), Positives = 67/130 (51%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD IS+H T LI+ E LA K ++VNA+RG ++DEVAL + +++ + GL Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGL 255 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 273 DVF EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 256 DVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVD 315 Query: 272 EPFLDEEATP 243 ++EE P Sbjct: 316 GGVVNEEVAP 325
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 67.8 bits (164), Expect = 3e-11 Identities = 42/114 (36%), Positives = 62/114 (54%), Gaps = 1/114 (0%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D I + L T L N + MK+ AV +N SRG V+++ L + L + + GL Sbjct: 209 SDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGL 268 Query: 452 DVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 294 DV EP L +KN V++PHI SA+ TR M+ LAA N+L ++G P+ Sbjct: 269 DVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 66.6 bits (161), Expect = 6e-11 Identities = 41/101 (40%), Positives = 61/101 (60%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 AD+++ H L+K+ T+HL++ E L+++ +L+NASRG VID AL+ LK Sbjct: 168 ADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLTALKCGKKL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 RV LDV+E EP + L E+ + + PHIA +T EG A Sbjct: 228 RVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/130 (33%), Positives = 64/130 (49%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + GL Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGL 255 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 273 DVF EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 256 DVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVG 315 Query: 272 EPFLDEEATP 243 ++EE P Sbjct: 316 GGVVNEEVAP 325
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/130 (33%), Positives = 64/130 (49%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + GL Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGL 255 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 273 DVF EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 256 DVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVG 315 Query: 272 EPFLDEEATP 243 ++EE P Sbjct: 316 GGVVNEEVAP 325
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 65.5 bits (158), Expect = 1e-10 Identities = 55/170 (32%), Positives = 81/170 (47%), Gaps = 22/170 (12%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + LK + L Sbjct: 236 SDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAAL 295 Query: 452 DVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLAALNVLGKI------ 309 DV E EP + + L + N + PH A AS RE AT + G+I Sbjct: 296 DVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRN 355 Query: 308 ---KGYPVWGNPNAVEPFLDEEATPPPA-------CPSIVNAKQLGLPSS 189 K + V P +V +D++A P P IV GLP++ Sbjct: 356 CVNKEFFVTSAPWSV---IDQQAIHPELNGATYRYPPGIVGVAPGGLPAA 402
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/114 (36%), Positives = 61/114 (53%), Gaps = 6/114 (5%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + LK + L Sbjct: 236 SDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAAL 295 Query: 452 DVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLAALNVLGKI 309 DV E EP + + L + N + PH A AS RE AT + G+I Sbjct: 296 DVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRI 349
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/118 (31%), Positives = 59/118 (50%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 449 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 VF +EP L +N + PH+ +++K + AL + +KG + G NA Sbjct: 260 VFTEEPPRDRALVNHENVISCPHLGASTKEAQSRCGEEIALQFVDMVKGKALAGVVNA 317
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 449 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 449 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 449 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 63.2 bits (152), Expect = 6e-10 Identities = 37/90 (41%), Positives = 52/90 (57%), Gaps = 4/90 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL L+ F Sbjct: 169 ADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQALKHRLQQADGF 228 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP + L + A PH+A Sbjct: 229 TAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 63.2 bits (152), Expect = 6e-10 Identities = 37/90 (41%), Positives = 52/90 (57%), Gaps = 4/90 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL L+ F Sbjct: 169 ADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQALKRRLQQADGF 228 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP + L + A PH+A Sbjct: 229 MAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 63.2 bits (152), Expect = 6e-10 Identities = 41/93 (44%), Positives = 52/93 (55%), Gaps = 4/93 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADVISLH L++ T HL++ RLA ++ LVNASRG V+D AL L+ Sbjct: 168 ADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRLLEGGADL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 V LDV+E EP P LA + + PHIA S Sbjct: 228 EVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 449 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRGRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 449 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 276 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLAGVVNA 317
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 63.2 bits (152), Expect = 6e-10 Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 2/112 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D I + L T L + + MK A+ +N SRG V+++ L + L + + GL Sbjct: 209 SDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAGL 268 Query: 452 DVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DV EP + P L +KN V++PHI SA+ TR M+ LAA N+L ++G Sbjct: 269 DVTTPEP-LPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRG 319
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 63.2 bits (152), Expect = 6e-10 Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 5/145 (3%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D +SLH L++ +HLIN + M+ A LVN +RG ++D+ L LK + L Sbjct: 230 SDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAAL 289 Query: 452 DVFEDEPY--MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPN 279 DV E+EPY + L + N + PH A S + + +AA + I G P+ Sbjct: 290 DVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVG----NIPD 345 Query: 278 AVEPFLDEE---ATPPPACPSIVNA 213 + +++E TPP A V A Sbjct: 346 VLRNCVNKEYFMRTPPAAAAGGVAA 370
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 62.8 bits (151), Expect = 8e-10 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 8/118 (6%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D I L L+ T HL+N E LA+++ A+LVN RG V+DE A++ L+ + Sbjct: 201 SDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAALERGQLGGYAA 260 Query: 452 DVFEDEPYMK--------PGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DVFE E + + P L N + PHI SA + R + AA N++ + G Sbjct: 261 DVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAAQNIIQVLAG 318
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 62.8 bits (151), Expect = 8e-10 Identities = 41/92 (44%), Positives = 53/92 (57%), Gaps = 4/92 (4%) Frame = -3 Query: 629 DVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 462 DVISLH L + T+HL+ +LA ++ A LVNASRGPV+D VAL E L Sbjct: 168 DVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVDNVALRELLLDREDVH 227 Query: 461 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP + LA++ + PHIA S Sbjct: 228 AVLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 62.8 bits (151), Expect = 8e-10 Identities = 40/116 (34%), Positives = 62/116 (53%), Gaps = 6/116 (5%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 DV+SLH +T +L+N R+A +K+ A+L+NA+RG V+D AL + LK + +D Sbjct: 206 DVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDALAQALKDGKLQGAAID 265 Query: 449 VFEDEP------YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 VF EP ++ P L E N ++ PHI ++ +E + V GK Y Sbjct: 266 VFPVEPASINEEFISP-LREFDNVILTPHIGGSTAEAQENI----GFEVAGKFVKY 316
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/92 (41%), Positives = 55/92 (59%), Gaps = 4/92 (4%) Frame = -3 Query: 629 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 462 DVISLH LDK+ T+HL++ RL +++ A L+NASRG V+D AL + + + Sbjct: 168 DVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVVDNRALHDVMLEREDLQ 227 Query: 461 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 LDV+E EP + LA++ + PHIA S Sbjct: 228 AVLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/105 (38%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 ADV L L TY ++N E L MK AVLVN RGP+I+ LV+ L + L Sbjct: 181 ADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGTIAGAAL 240 Query: 452 DVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 321 DV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 241 DVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 452 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 452 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 452 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 452 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 300 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 61.2 bits (147), Expect = 2e-09 Identities = 45/128 (35%), Positives = 64/128 (50%), Gaps = 6/128 (4%) Frame = -3 Query: 632 ADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADVI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D AL L+ F Sbjct: 169 ADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALKARLQQGDGF 228 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLGKIKGYPVW 291 LDVFE EP + L + A PHIA + EG A T N + G Sbjct: 229 TAVLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKARGTTMIFNSYCEFLGSAHC 284 Query: 290 GNPNAVEP 267 NP ++ P Sbjct: 285 ANPASLLP 292
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 60.5 bits (145), Expect = 4e-09 Identities = 39/105 (37%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 ADV L L TY ++N E L MK AV+VN RGP+I+ LV+ L + L Sbjct: 181 ADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGTIAGAAL 240 Query: 452 DVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 321 DV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 241 DVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 60.5 bits (145), Expect = 4e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 230 SDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 289 Query: 452 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 290 DVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 230 SDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 289 Query: 452 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 290 DVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 230 SDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 289 Query: 452 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 290 DVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 60.1 bits (144), Expect = 5e-09 Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 14/124 (11%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 ADVISLH H+IN + +A MK++ V+VN SRGP++D A++ L + +F + Sbjct: 199 ADVISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKVFGYAM 258 Query: 452 DVFEDE-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLG 315 DV+E E + LA++ N +V PH A + M A N L Sbjct: 259 DVYEGEVGVFNEDREGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNLE 318 Query: 314 KIKG 303 ++G Sbjct: 319 LVEG 322
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 219 SDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 278 Query: 452 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 303 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 279 DVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 330
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 4/90 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 +D+I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D AL + L F Sbjct: 169 SDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQALKQRLMKQDGF 228 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP + L + A PH+A Sbjct: 229 TAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/93 (39%), Positives = 54/93 (58%), Gaps = 4/93 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 +D+I+LH L + T+HLIN + L +K +L+N SRG VID +L+ LK Sbjct: 167 SDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILINTSRGSVIDNNSLLNILKEGKPI 226 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 RV LDV+E+EP + L + + + PHIA S Sbjct: 227 RVVLDVWENEPLICSKLLSLID-IGTPHIAGHS 258
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 58.2 bits (139), Expect = 2e-08 Identities = 29/66 (43%), Positives = 40/66 (60%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DVISLH L YHL+N MK ++VN SRG +ID A +E LK + +G+ Sbjct: 198 SDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGM 257 Query: 452 DVFEDE 435 DV+E+E Sbjct: 258 DVYENE 263
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 57.4 bits (137), Expect = 3e-08 Identities = 41/93 (44%), Positives = 54/93 (58%), Gaps = 4/93 (4%) Frame = -3 Query: 629 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 462 D++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL L+ + + Sbjct: 169 DLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCDHVIT 225 Query: 461 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 363 LDV+E+EP + L E K + PHIA SK Sbjct: 226 C-LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256
>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 57.4 bits (137), Expect = 3e-08 Identities = 39/101 (38%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ L A Sbjct: 168 ADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + L E + + HIA +T EG A Sbjct: 228 SVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 57.4 bits (137), Expect = 3e-08 Identities = 39/101 (38%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ L A Sbjct: 168 ADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + L E + + HIA +T EG A Sbjct: 228 SVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 57.0 bits (136), Expect = 5e-08 Identities = 30/93 (32%), Positives = 48/93 (51%) Frame = -3 Query: 620 SLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 441 SL+ T + N + + + A++VN +RG ++D +V L+A + G DVF Sbjct: 208 SLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFA 267 Query: 440 DEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 EP + G ++ N + PHI SA+ RE MA Sbjct: 268 GEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 300
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 2/88 (2%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D I+LH L++ +HLIN + M++ LVN +RG ++DE AL + LK + L Sbjct: 233 SDCITLHCNLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKDGRIRGAAL 292 Query: 452 DVFEDEP--YMKPGLAEMKNAVVVPHIA 375 DV E EP + + L + N + PH A Sbjct: 293 DVHESEPFSFSQGPLKDAPNLICTPHTA 320
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 56.6 bits (135), Expect = 6e-08 Identities = 38/110 (34%), Positives = 53/110 (48%), Gaps = 14/110 (12%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DVISLH K ++HLIN + +A MK LVN +RG VID AL++ L + L Sbjct: 199 SDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALLDSLDKGKIAGAAL 258 Query: 452 DVFEDE-PYMKPG-------------LAEMKNAVVVPHIASASKWTREGM 345 D +E E PY+ L + + PHIA ++ E M Sbjct: 259 DAYEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETAIENM 308
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/66 (43%), Positives = 41/66 (62%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D+ISLH L +H+IN E LA KK LVN SRG ++D A+++ LKA + Sbjct: 200 SDIISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVDTKAVIKSLKAKHLGGYAA 259 Query: 452 DVFEDE 435 DV+E+E Sbjct: 260 DVYEEE 265
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 55.8 bits (133), Expect = 1e-07 Identities = 39/102 (38%), Positives = 56/102 (54%), Gaps = 5/102 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ L+ Sbjct: 168 ADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKKL 227 Query: 464 RVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 228 SVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 55.8 bits (133), Expect = 1e-07 Identities = 39/102 (38%), Positives = 56/102 (54%), Gaps = 5/102 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 ADV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ L+ Sbjct: 168 ADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKKL 227 Query: 464 RVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 228 SVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 55.8 bits (133), Expect = 1e-07 Identities = 29/92 (31%), Positives = 49/92 (53%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DVIS++ L T+ LI+ + MK ++N +RG +I+E A ++ +K+ + R GL Sbjct: 215 SDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGL 274 Query: 452 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 357 DVF +EP E + PH + +T Sbjct: 275 DVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D+++LH L+ T+++I+ E++ MK+ A L+N RGP++D LV+ L+ + L Sbjct: 195 SDIVTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDTYELVKALENGKLGGAAL 254 Query: 452 DVFEDEP-------YMKP-------GLAEMKNAVVVPHIA 375 DV E E KP L M N ++ PH A Sbjct: 255 DVLEGEEEFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTA 294
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 14/124 (11%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 ADVISLH H+IN + +A MK V+VN SRG ++D A++ L + +F + Sbjct: 199 ADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVM 258 Query: 452 DVFEDE-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVLG 315 D +EDE + LA++ N +V PH A + M A N L Sbjct: 259 DTYEDEVGVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNLK 318 Query: 314 KIKG 303 I G Sbjct: 319 LING 322
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 13/103 (12%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD +SLH T ++I+ + A MK+ + L+NASRG V+D ALV+ K+ + + Sbjct: 248 ADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALVDASKSGKIAGAAI 307 Query: 452 DVFEDEP-------------YMKPGLAEMKNAVVVPHIASASK 363 DV+ EP L KN ++ PHI +++ Sbjct: 308 DVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/64 (42%), Positives = 39/64 (60%) Frame = -3 Query: 626 VISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDV 447 VI+LH YHL+N E A MK ++VN SRG +ID A ++ LK + +G+DV Sbjct: 200 VITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALGMDV 259 Query: 446 FEDE 435 +E+E Sbjct: 260 YENE 263
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 4/93 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 AD+ISLH + +T T HL + RL +K L+N RG VID AL++ + Sbjct: 169 ADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVIDNQALIKVKQQRDDL 228 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 ++ LDV+E EP P L PHIA S Sbjct: 229 KLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/101 (36%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + L + K + PHIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 15/101 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D+++LH L T HLI ++ MK+ A L+N RG ++D +LVE L + + L Sbjct: 196 SDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSGKLGGAAL 255 Query: 452 DVFE---------------DEPYMKPGLAEMKNAVVVPHIA 375 DV E D P++ L M N ++ PH A Sbjct: 256 DVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + L K + PHIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + L K + PHIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 53.1 bits (126), Expect = 7e-07 Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 15/101 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + + + Sbjct: 199 ADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNNGTLSGAAI 258 Query: 452 DVFE---------------DEPYMKPGLAEMKNAVVVPHIA 375 D +E D+P + L +N +V PHIA Sbjct: 259 DTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 53.1 bits (126), Expect = 7e-07 Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 15/101 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + + + Sbjct: 199 ADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNNGTLSGAAI 258 Query: 452 DVFE---------------DEPYMKPGLAEMKNAVVVPHIA 375 D +E D+P + L +N +V PHIA Sbjct: 259 DTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L++ + + + Sbjct: 199 ADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVNDGTLLGAAI 258 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIA 375 D +E+E L E + +V PHIA Sbjct: 259 DTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/94 (37%), Positives = 52/94 (55%), Gaps = 9/94 (9%) Frame = -3 Query: 629 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN---- 474 DVI++H + K T+HLIN + ++ +A+L+NA+RGPV D AL + L+ + Sbjct: 170 DVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQALKKALQLSQSGL 229 Query: 473 -PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 375 LDVFE EP++ L + A PHIA Sbjct: 230 GKKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 52.0 bits (123), Expect = 1e-06 Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 14/104 (13%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D ++LH T +++ + A MK A ++NASRG V+D +L++ +KAN + L Sbjct: 251 SDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAAL 310 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 363 DV+ EP K G L + N ++ PHI +++ Sbjct: 311 DVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 52.0 bits (123), Expect = 1e-06 Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 14/104 (13%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +D ++LH T +++ + A MK A ++NASRG V+D +L++ +KAN + L Sbjct: 251 SDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAAL 310 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 363 DV+ EP K G L + N ++ PHI +++ Sbjct: 311 DVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD ISL+ +HLIN + +A MK V++NA+RG ++D A+++ L + + G+ Sbjct: 199 ADAISLYVPGVPENHHLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFGM 258 Query: 452 DVFEDEP--YMKPGLAE------------MKNAVVVPHIA 375 DV+E+E MK GL + +N ++ PH A Sbjct: 259 DVYENEVACSMKIGLVKNSPDAKIADLIARENVMITPHTA 298
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 52.0 bits (123), Expect = 1e-06 Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVL----DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 AD+++LH L T+HL++ L +L+NA RGPV+D AL+E L+ Sbjct: 168 ADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLEALQQGKKL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + L + + HIA +T EG A Sbjct: 228 SVILDVWEPEPGLSTDLLARVD-IGTAHIAG---YTLEGKA 264
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = -3 Query: 629 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 462 DVISLH + KT T++L + RL +K+ L+N RG VID AL++ P + Sbjct: 56 DVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVIDNQALIKVKLERPDIK 115 Query: 461 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 + LDV+E EP L + + PHIA S Sbjct: 116 LVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + + Sbjct: 199 ADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAI 258 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIA 375 D +E+E L E + +V PHIA Sbjct: 259 DTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + + Sbjct: 199 ADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAI 258 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIA 375 D +E+E L E + +V PHIA Sbjct: 259 DTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + + Sbjct: 199 ADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAI 258 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIA 375 D +E+E L E + +V PHIA Sbjct: 259 DTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + + Sbjct: 199 ADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAI 258 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIA 375 D +E+E L E + +V PHIA Sbjct: 259 DTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + + Sbjct: 199 ADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAI 258 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIA 375 D +E+E L E + +V PHIA Sbjct: 259 DTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 51.2 bits (121), Expect = 2e-06 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 14/100 (14%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + + Sbjct: 199 ADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAI 258 Query: 452 DVFEDEPYMKPG--------------LAEMKNAVVVPHIA 375 D +E+E L E + +V PHIA Sbjct: 259 DTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 50.8 bits (120), Expect = 3e-06 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 15/101 (14%) Frame = -3 Query: 632 ADVISLH-PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 456 +DVI LH P +++ T H+IN +MK A+++N +R +ID A++ +LK+ + VG Sbjct: 198 SDVIDLHVPGIEQNT-HIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVG 256 Query: 455 LDVFEDEPYMKPGLAE--------------MKNAVVVPHIA 375 +D +E E LA+ M N V+ PHIA Sbjct: 257 IDTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 342 V LDV+E EP + L + K + HIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 50.4 bits (119), Expect = 4e-06 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = -3 Query: 629 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 462 DVISLH + KT T++L + RL +K L+N RG VID AL++ + P + Sbjct: 56 DVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVIDNRALIKVKQQRPDIK 115 Query: 461 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 + LDV+E EP L + + PHIA S Sbjct: 116 LVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 49.3 bits (116), Expect = 9e-06 Identities = 44/155 (28%), Positives = 63/155 (40%), Gaps = 15/155 (9%) Frame = -3 Query: 629 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 462 D+I+ H L K TYHL + ++++ V++N SRG VI+ AL+E + + Sbjct: 170 DIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNALLEAINNGIISD 229 Query: 461 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNP 282 +DV+E EP + L E K + PHIA GY G Sbjct: 230 AVIDVWEHEPEINRELLE-KVLIGTPHIA-----------------------GYSADGKA 265 Query: 281 NAVEPFLDE-----------EATPPPACPSIVNAK 210 NA LD E TPP ++ AK Sbjct: 266 NATRMSLDSICRFFHLSATYEITPPAPSSPLIEAK 300
>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)| Length = 379 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Frame = -3 Query: 593 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL 414 T HLIN + L +LVN RG ++D A+ + L + +GLDVF EP + + Sbjct: 270 TEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINHLGLDVFNKEPEIDEKI 329 Query: 413 AEMKNAV-VVPHIASASKWTREGMATLAALNVLGKIKG 303 + PH+ SA+K E LA +L + G Sbjct: 330 RSSDRLTSITPHLGSATKDVFEQSCELALTRILRVVSG 367
>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)| Length = 396 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+I L +T ++IN + LA K +VN RG IDE L++ L++ + GL Sbjct: 277 ADLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGL 336 Query: 452 DVFE-DEPYMKPGLAEMKNAVVVPHIAS 372 DVF+ +E +K L + +PHI S Sbjct: 337 DVFKNEETRVKQELLRRWDVTALPHIGS 364
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 47.8 bits (112), Expect = 3e-05 Identities = 24/66 (36%), Positives = 38/66 (57%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 ADVI+LH K YH++N + + MK A ++N +RG +ID L++ L + + L Sbjct: 199 ADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAAL 258 Query: 452 DVFEDE 435 D +E E Sbjct: 259 DTYEYE 264
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Frame = -3 Query: 632 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 465 +D+++LH L T T+H+IN + L + ++L+N SRG V++ L+ L+ Sbjct: 169 SDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVVNNDDLLAILRCGKKI 228 Query: 464 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 366 V LDV+E EP + L + + HIA S Sbjct: 229 NVILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 DVI ++ L + T + N ER+A MKK ++VN +RG ++D A+ + + + G D Sbjct: 247 DVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQAVADACSSGQVAGYGGD 306 Query: 449 VFEDEPYMKP-GLAEMKNAVVVPHIASAS 366 V+ +P K M N + PHI+ + Sbjct: 307 VWFPQPAPKDHPWRYMPNHAMTPHISGTT 335
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 46.6 bits (109), Expect = 6e-05 Identities = 30/117 (25%), Positives = 55/117 (47%), Gaps = 14/117 (11%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 A+VI+LH K YH+++ + M+ ++N +RG ++D AL++ L + + L Sbjct: 198 ANVITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAAL 257 Query: 452 DVFE-----------DEPYMKP---GLAEMKNAVVVPHIASASKWTREGMATLAALN 324 D +E D+P P L +N ++ PH A ++ + M +A N Sbjct: 258 DTYENEVGIFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALDN 314
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 46.2 bits (108), Expect = 8e-05 Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD++SLH HL N + KK A+L+N +RG VI+ L++ L A + G+ Sbjct: 199 ADLVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGI 258 Query: 452 DVFEDE-PYM 426 D +E E PY+ Sbjct: 259 DTYEFEGPYI 268
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 DV+ ++ L + T + N E++A MKK ++VN +RG ++D A+ + + + G D Sbjct: 248 DVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYGGD 307 Query: 449 VFEDEPYMKP-GLAEMKNAVVVPHIASAS 366 V+ +P K M N + PHI+ + Sbjct: 308 VWFPQPAPKDHPWRYMPNHAMTPHISGTT 336
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 44.3 bits (103), Expect = 3e-04 Identities = 23/66 (34%), Positives = 37/66 (56%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 ADVI+LH K YH++N + + MK A ++N +RG +ID L++ L + + L Sbjct: 199 ADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAAL 258 Query: 452 DVFEDE 435 +E E Sbjct: 259 VTYEYE 264
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 43.5 bits (101), Expect = 5e-04 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD++SLH HL N + KK A+L+N +RG +++ L+E L + G+ Sbjct: 199 ADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGI 258 Query: 452 DVFEDE-PYM 426 D +E E PY+ Sbjct: 259 DTYEFEGPYI 268
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 43.5 bits (101), Expect = 5e-04 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 1/70 (1%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD++SLH HL N + KK A+L+N +RG +++ L+E L + G+ Sbjct: 199 ADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAGI 258 Query: 452 DVFEDE-PYM 426 D +E E PY+ Sbjct: 259 DTYEFEGPYI 268
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 42.7 bits (99), Expect = 9e-04 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 DV+ ++ L + T + N ER+A MKK +VN +RG ++D A+ + + + G D Sbjct: 249 DVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQAVADACASGHVAGYGGD 308 Query: 449 VFEDEPYMKP-GLAEMKNAVVVPHIASAS 366 V+ +P K M N + PH + + Sbjct: 309 VWFPQPAPKDHPWRYMPNHAMTPHCSGTT 337
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/89 (26%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 D++ ++ L + T + + ER+A +KK ++VN +RG ++D A+V+ + + D Sbjct: 252 DIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVDACNSGHIAGYSGD 311 Query: 449 VFEDEPYMKP-GLAEMKNAVVVPHIASAS 366 V+ +P K M N + PHI+ + Sbjct: 312 VWYPQPAPKDHPWRYMPNQAMTPHISGTT 340
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/69 (33%), Positives = 38/69 (55%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 DV++L+ L T H+IN E L + K+ A +VN +RG + D A+ L++ + D Sbjct: 249 DVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGD 308 Query: 449 VFEDEPYMK 423 V+ +P K Sbjct: 309 VWFPQPAPK 317
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 6/94 (6%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 DV++++ L + T L N E ++ MKK + LVN +RG ++ + + E LK+ + G D Sbjct: 224 DVVTINCPLHEKTQGLFNKELISKMKKGSWLVNTARGAIVVKEDVAEALKSGHLRGYGGD 283 Query: 449 VFEDEPYMKP-GLAEMKNA-----VVVPHIASAS 366 V+ +P + L KN +VPH++ S Sbjct: 284 VWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 39.7 bits (91), Expect = 0.008 Identities = 23/89 (25%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 450 DVI ++ L + T + N E + +KK ++VN +RG +++ A+V+ +++ + D Sbjct: 255 DVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVESGHIGGYSGD 314 Query: 449 VFEDEPYMKP-GLAEMKNAVVVPHIASAS 366 V++ +P K M N + PH + + Sbjct: 315 VWDPQPAPKDHPWRYMPNQAMTPHTSGTT 343
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 37.7 bits (86), Expect = 0.029 Identities = 21/70 (30%), Positives = 39/70 (55%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DV++++ L K + L N + ++ MK A LVN +RG + + E +K+ + G Sbjct: 236 SDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGG 295 Query: 452 DVFEDEPYMK 423 DV++ +P K Sbjct: 296 DVWDKQPAPK 305
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 37.7 bits (86), Expect = 0.029 Identities = 21/70 (30%), Positives = 39/70 (55%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 +DV++++ L K + L N + ++ MK A LVN +RG + + E +K+ + G Sbjct: 236 SDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYGG 295 Query: 452 DVFEDEPYMK 423 DV++ +P K Sbjct: 296 DVWDKQPAPK 305
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 33.5 bits (75), Expect = 0.54 Identities = 21/70 (30%), Positives = 36/70 (51%) Frame = -3 Query: 632 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 453 AD+++++ L + L+N E L KK A LVN +RG + + +K+ + G Sbjct: 221 ADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVNTARGAICVAEDVAAAVKSGQLRGYGG 280 Query: 452 DVFEDEPYMK 423 DV+ +P K Sbjct: 281 DVWFPQPAPK 290
>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)| Length = 325 Score = 32.3 bits (72), Expect = 1.2 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = -3 Query: 593 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPG 417 T +IN + L + A L+N +RG + E L+ L + + LDVF EP + Sbjct: 217 TVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESP 276 Query: 416 LAEMKNAVVVPHIASASK 363 L + + PH+A+ ++ Sbjct: 277 LWQHPRVTITPHVAAITR 294
>NIP7_YEAST (Q08962) 60S ribosome subunit biogenesis protein NIP7| Length = 181 Score = 31.2 bits (69), Expect = 2.7 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Frame = -3 Query: 431 YMKPGLAEMKNAVVVPHIASAS----KWTREGMATL--AALNVLGKIKGYPVWGNPNAVE 270 Y+ +A++ +V P++ S K+T+ G L +L VL K Y +W PN Sbjct: 46 YVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEM 105 Query: 269 PFL 261 PFL Sbjct: 106 PFL 108
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 29.6 bits (65), Expect = 7.8 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 17/86 (19%) Frame = -3 Query: 629 DVISLHPVLDKTTYHLINPERLAMMK-----------------KEAVLVNASRGPVIDEV 501 DV++++ L + T L N E ++ MK K + LVN +RG ++ + Sbjct: 219 DVVTINCPLHEKTRGLFNKELISKMKPGKSALLYLIIPMLMYHKGSWLVNTARGAIVVKE 278 Query: 500 ALVEHLKANPMFRVGLDVFEDEPYMK 423 + E LK+ + G DV+ +P K Sbjct: 279 DVAEALKSGHLRGYGGDVWFPQPAPK 304
>NUOL_BUCAI (P57262) NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH| dehydrogenase I, chain L) (NDH-1, chain L) Length = 614 Score = 29.6 bits (65), Expect = 7.8 Identities = 13/50 (26%), Positives = 24/50 (48%) Frame = +1 Query: 475 LALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLI 624 ++ R S + I L T +F+++ + +G++RWYV G I Sbjct: 555 ISKRLSADPLNKIINYFLKVTQIFNFYLLKTSNGYVRWYVASMILGINFI 604 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,105,441 Number of Sequences: 219361 Number of extensions: 1768905 Number of successful extensions: 5480 Number of sequences better than 10.0: 119 Number of HSP's better than 10.0 without gapping: 5245 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5458 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5881538857 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
