ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal30b02 |
|---|---|
| Clone Library Name | barley_pub |
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 97.1 bits (240), Expect = 4e-20 Identities = 59/154 (38%), Positives = 83/154 (53%), Gaps = 3/154 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVVM 468 L DD AK++DFGL +L + T++ GT GYLAPE+ +T ++T K DVYSFGV++M Sbjct: 725 LGDDMRAKVADFGLVRLAPEGKGSIETRIAGTFGYLAPEYAVTGRVTTKVDVYSFGVILM 784 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKV--KNAHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 E+I GRK+LD S EESIHL++ + K A ID + V + +LA Sbjct: 785 ELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELA 844 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHN 192 C + +RP M V +L + D N Sbjct: 845 GHCCAREPYQRPDMGHAVNILSSLVELWKPSDQN 878
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 94.4 bits (233), Expect = 3e-19 Identities = 53/148 (35%), Positives = 94/148 (63%), Gaps = 3/148 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVVM 468 LD++F A + DFGL KL+D + V T +RGT G++APE+L T + +EK DV+ +GV+++ Sbjct: 424 LDEEFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVMLL 483 Query: 467 EVICGRKNLDTS--LSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 E+I G++ D + +++ + L+ ++ +K L L+D + ++V +++++A Sbjct: 484 ELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNY-KDEEVEQLIQVA 542 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAE 210 + C Q RPKMS+VV++LEG AE Sbjct: 543 LLCTQSSPMERPKMSEVVRMLEGDGLAE 570
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 93.6 bits (231), Expect = 4e-19 Identities = 59/160 (36%), Positives = 92/160 (57%), Gaps = 3/160 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLID-RDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD ++NAKLSDFGL K D S V T++ GT GY APE+L T +T K+DVYSFGVV+ Sbjct: 211 LDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSDVYSFGVVL 270 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAH-LVDLIDKNSNDMLAHKQDVIEIMKLA 294 +E++ GR+ +D + +L+ + + N + +ID D + ++ ++ L+ Sbjct: 271 LELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRLQDQYS-MEEACKVATLS 329 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVATNQ 174 + CL + K RP MS+VV LE + + I N T++ Sbjct: 330 LRCLTTEIKLRPNMSEVVSHLEHIQSLNAAIGGNMDKTDR 369
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 91.3 bits (225), Expect = 2e-18 Identities = 57/142 (40%), Positives = 83/142 (58%), Gaps = 3/142 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD ++NAKLSDFGL K D S V T++ GT GY APE+L T +T K+DVYS+GVV+ Sbjct: 212 LDSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATGHLTTKSDVYSYGVVL 271 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAH-LVDLIDKNSNDMLAHKQDVIEIMKLA 294 +EV+ GR+ +D + L+ + N L +ID D + ++ ++ LA Sbjct: 272 LEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQYS-MEEACKVATLA 330 Query: 293 MWCLQIDCKRRPKMSDVVKVLE 228 + CL + K RP M++VV LE Sbjct: 331 LRCLTFEIKLRPNMNEVVSHLE 352
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 89.4 bits (220), Expect = 8e-18 Identities = 63/174 (36%), Positives = 94/174 (54%), Gaps = 3/174 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRD-MSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD +++AKLSDFGL KL D S V T++ GT GY APE++ T + K+DV++FGVV+ Sbjct: 226 LDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVL 285 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLV-DLIDKNSNDMLAHKQDVIEIMKLA 294 +E++ G +T L+ L ++ N H V ++DK K E+ ++ Sbjct: 286 LEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKV-ATEMARIT 344 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVATNQVNFGAAANVLSSVP 132 + C++ D K RP M +VV+VLE N+ N +T Q A AN S P Sbjct: 345 LSCIEPDPKNRPHMKEVVEVLEHIQGL--NVVPNRSSTKQ----AVANSSRSSP 392
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 89.0 bits (219), Expect = 1e-17 Identities = 54/142 (38%), Positives = 86/142 (60%), Gaps = 3/142 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD ++NAKLSDFGL + D S V T++ GT GY APE+L T ++ K+DVYSFGVV+ Sbjct: 211 LDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVVL 270 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKN-AHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 +E++ GR+ +D + +L+ + N L+ ++D + + ++I LA Sbjct: 271 LELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTR-ALKIAVLA 329 Query: 293 MWCLQIDCKRRPKMSDVVKVLE 228 + C+ ID K RP M+++VK +E Sbjct: 330 LDCISIDAKSRPTMNEIVKTME 351
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 87.0 bits (214), Expect = 4e-17 Identities = 52/141 (36%), Positives = 82/141 (58%), Gaps = 2/141 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVVM 468 LD DF K++DFGL +LI S V T + GT GY+ PE+ +++ T K DVYSFGV+++ Sbjct: 1051 LDGDFEPKVADFGLARLISACESHVSTVIAGTFGYIPPEYGQSARATTKGDVYSFGVILL 1110 Query: 467 EVICGRKNLDTSLSE-ESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 E++ G++ E E +L+ +K+ VD+ID +A K + ++++AM Sbjct: 1111 ELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVS-VALKNSQLRLLQIAM 1169 Query: 290 WCLQIDCKRRPKMSDVVKVLE 228 CL +RP M DV+K L+ Sbjct: 1170 LCLAETPAKRPNMLDVLKALK 1190
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 85.5 bits (210), Expect = 1e-16 Identities = 58/149 (38%), Positives = 82/149 (55%), Gaps = 6/149 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVV 471 LD+ F+ KLSDFGL KL D S V T++ GT GY APE+ +T Q+T K+DVYSFGVV Sbjct: 221 LDEGFHPKLSDFGLAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTGQLTVKSDVYSFGVVF 280 Query: 470 MEVICGRKNLDTSLSEESIHLIT----LLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIM 303 +E+I GRK +D+ + +L+ L ++ K L D K A + + + Sbjct: 281 LELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRA----LYQAL 336 Query: 302 KLAMWCLQIDCKRRPKMSDVVKVLEGTMN 216 +A C+Q RP ++DVV L N Sbjct: 337 AVASMCIQEQAATRPLIADVVTALSYLAN 365
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 84.3 bits (207), Expect = 3e-16 Identities = 54/148 (36%), Positives = 87/148 (58%), Gaps = 10/148 (6%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMS-QVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD F K++DFGL KL++R S Q V+ +RGT GY+APEW++S IT K DVYS+GVV+ Sbjct: 666 LDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVDVYSYGVVL 725 Query: 470 MEVICGRKNLDTSLSEESIH-----LITLLEEKV---KNAHLVDLIDKNSNDMLAHKQDV 315 +E++ G + + + +H L+ +L K+ + + + +D N + + Q Sbjct: 726 LELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQ-A 784 Query: 314 IEIMKLAMWCLQIDCKRRPKMSDVVKVL 231 ++KLA+ CL+ D +RP M V+ L Sbjct: 785 RTLIKLAVSCLEEDRSKRPTMEHAVQTL 812
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 83.2 bits (204), Expect = 6e-16 Identities = 52/155 (33%), Positives = 89/155 (57%), Gaps = 7/155 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCK-LIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD DF A ++DFGL K L+D S+ ++ + G+ GY+APE+ T ++ EK+DVYSFGVV+ Sbjct: 825 LDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVL 884 Query: 470 MEVICGRKNL-DTSLSEESIHLITLLEEKVKN----AHLVDLIDKNSNDMLAHKQDVIEI 306 +E+I G+K + + + + + EE++ A +V ++D VI + Sbjct: 885 LELIAGKKPVGEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTGY--PLTSVIHV 942 Query: 305 MKLAMWCLQIDCKRRPKMSDVVKVLEGTMNAESNI 201 K+AM C++ + RP M +VV +L + +N+ Sbjct: 943 FKIAMMCVEEEAAARPTMREVVHMLTNPPKSVANL 977
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 80.9 bits (198), Expect = 3e-15 Identities = 45/143 (31%), Positives = 85/143 (59%), Gaps = 8/143 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTSQI-TEKADVYSFGVVV 471 LD + K+SDFG+ ++ +RD ++ T K+ GT GY++PE+ I +EK+DV+SFGV+V Sbjct: 661 LDKNMIPKISDFGMARIFERDETEANTMKVVGTYGYMSPEYAMYGIFSEKSDVFSFGVIV 720 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDK------NSNDMLAHKQDVIE 309 +E++ G+KN + L++ + + K ++++D +S + Q+V++ Sbjct: 721 LEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVDPVIVDSLSSQPSIFQPQEVLK 780 Query: 308 IMKLAMWCLQIDCKRRPKMSDVV 240 +++ + C+Q + RP MS VV Sbjct: 781 CIQIGLLCVQELAEHRPAMSSVV 803
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 80.9 bits (198), Expect = 3e-15 Identities = 47/149 (31%), Positives = 86/149 (57%), Gaps = 2/149 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD AK++DFG K ++ V+ ++RGT GYL PE+ T Q++EK+DV+SFGVV+ Sbjct: 729 LDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVVL 788 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 +E++ GR+ L+ L+ + ++ + + +++D H + + ++++A+ Sbjct: 789 LEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIKGGY-HAEALWRVVEVAL 847 Query: 290 WCLQIDCKRRPKMSDVVKVLEGTMNAESN 204 CL+ RP M D+V+ LE + E+N Sbjct: 848 QCLEPYSTYRPCMVDIVRELEDALIIENN 876
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 80.9 bits (198), Expect = 3e-15 Identities = 47/149 (31%), Positives = 86/149 (57%), Gaps = 2/149 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD AK++DFG K ++ V+ ++RGT GYL PE+ T Q++EK+DV+SFGVV+ Sbjct: 730 LDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKTQQLSEKSDVFSFGVVL 789 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 +E++ GR+ L+ L+ + ++ + + +++D H + + ++++A+ Sbjct: 790 LEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIKGGY-HAEALWRVVEVAL 848 Query: 290 WCLQIDCKRRPKMSDVVKVLEGTMNAESN 204 CL+ RP M D+V+ LE + E+N Sbjct: 849 QCLEPYSTYRPCMVDIVRELEDALIIENN 877
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 80.5 bits (197), Expect = 4e-15 Identities = 50/142 (35%), Positives = 81/142 (57%), Gaps = 3/142 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTSQITEKADVYSFGVVVM 468 LD+ F AK+SDFGL + ++ V+T ++ GT Y+APE L +IT K+D+YSFGVV++ Sbjct: 319 LDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLL 378 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAH--LVDLIDKNSNDMLAHKQDVIEIMKLA 294 E+I G +D L+ ++E++++ + D IDK ND A V + +A Sbjct: 379 EIITGLPAVD---EHREPQLLLDIKEEIEDEEKTIEDYIDKKMND--ADSTSVEAMYSVA 433 Query: 293 MWCLQIDCKRRPKMSDVVKVLE 228 CL +RP + V ++L+ Sbjct: 434 SQCLHEKKNKRPDIKKVQQLLQ 455
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 79.7 bits (195), Expect = 7e-15 Identities = 53/157 (33%), Positives = 89/157 (56%), Gaps = 6/157 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKL-IDRDMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVV 471 L +D+ KLSDFGL K+ D + V T++ GT GY AP++ +T Q+T K+D+YSFGVV+ Sbjct: 238 LGEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSFGVVL 297 Query: 470 MEVICGRKNLDTSLSEESIHLI----TLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIM 303 +E+I GRK +D + + + +L+ L +++ +VD + + + + + + + Sbjct: 298 LELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPV----RGLYQAL 353 Query: 302 KLAMWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHN 192 ++ C+Q RP +SDVV L A S D N Sbjct: 354 AISAMCVQEQPTMRPVVSDVVLAL--NFLASSKYDPN 388
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 79.0 bits (193), Expect = 1e-14 Identities = 44/151 (29%), Positives = 83/151 (54%), Gaps = 2/151 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD DF A++SDFG+ +L+ D V+ + GTPGY+ PE+ S + T K DVYS+GV++ Sbjct: 993 LDQDFVARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVIL 1052 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 +E++ G+K +D E +L+ ++ + +++D + +++ +K+A Sbjct: 1053 LELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHYLKIAS 1112 Query: 290 WCLQIDCKRRPKMSDVVKVLEGTMNAESNID 198 CL +RP M V+ + + + ++ D Sbjct: 1113 QCLDDRPFKRPTMIQVMTMFKELVQVDTEND 1143
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 79.0 bits (193), Expect = 1e-14 Identities = 48/143 (33%), Positives = 82/143 (57%), Gaps = 5/143 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPE-WLTSQITEKADVYSFGVVV 471 LD D +SDFG+ KL+D+ + + + ++GT GY+APE T+ + ++DVYS+GVV+ Sbjct: 950 LDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRESDVYSYGVVL 1009 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHK---QDVIEIMK 300 +E+I +K LD S + E+ + + + + ++D + D L + V E + Sbjct: 1010 LELITRKKALDPSFNGETDIVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEALS 1069 Query: 299 LAMWCLQIDCKRRPKMSDVVKVL 231 LA+ C + + +RP M DVVK L Sbjct: 1070 LALRCAEKEVDKRPTMRDVVKQL 1092
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 78.6 bits (192), Expect = 1e-14 Identities = 45/153 (29%), Positives = 85/153 (55%), Gaps = 2/153 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD+DF A++SDFG+ +L+ D V+ + GTPGY+ PE+ S + T K DVYS+GV++ Sbjct: 995 LDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSYGVIL 1054 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 +E++ G+K +D E +L+ ++ + +++D + ++ +K+A Sbjct: 1055 LELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHYLKIAS 1114 Query: 290 WCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHN 192 CL +RP M ++ + + M A++ D + Sbjct: 1115 QCLDDRPFKRPTMIQLMAMFK-EMKADTEEDES 1146
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 76.6 bits (187), Expect = 6e-14 Identities = 50/142 (35%), Positives = 81/142 (57%), Gaps = 3/142 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTSQITEKADVYSFGVVVM 468 LD DF AK+SDFGL + R V+T ++ GT Y+APE L +IT K+D+YSFGVV++ Sbjct: 319 LDKDFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLL 378 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAH--LVDLIDKNSNDMLAHKQDVIEIMKLA 294 E+I G +D + + L+ ++E++++ + D D+ +D A V + A Sbjct: 379 ELITGLAAVDENREPQ---LLLDIKEEIEDEEKTIEDYTDEKMSD--ADPASVEAMYSAA 433 Query: 293 MWCLQIDCKRRPKMSDVVKVLE 228 CL RRP ++ V ++L+ Sbjct: 434 SQCLHEKKNRRPDIAKVQQLLQ 455
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 76.3 bits (186), Expect = 7e-14 Identities = 50/162 (30%), Positives = 85/162 (52%), Gaps = 15/162 (9%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD D A++SDFG+ +LI D V+ + GTPGY+ PE+ S + T K DVYS GVV+ Sbjct: 974 LDQDMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKGDVYSIGVVM 1033 Query: 470 MEVICGRKNL------DTSL-------SEESIHLITLLEEKVKNAHLVDLIDKNSNDMLA 330 +E++ G++ DT+L + E H+ + E+ +K L +K + Sbjct: 1034 LEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGV 1093 Query: 329 HKQDVIEIMKLAMWCLQIDCKRRPKMSDVVKVLEGTMNAESN 204 ++++ +++A+ C+ +RP M VV L +E+N Sbjct: 1094 IVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELRGSENN 1135
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 75.1 bits (183), Expect = 2e-13 Identities = 49/140 (35%), Positives = 76/140 (54%), Gaps = 1/140 (0%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVVM 468 L D F A L+DFGL +LI + V T + GT GY+ PE+ S T K DVYSFGVV++ Sbjct: 877 LSDTFVAHLADFGLARLILPYDTHVTTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLL 936 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMW 288 E++ GR+ +D S LI+ + + ++ D D H ++++ ++++A Sbjct: 937 ELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIYDK-DHAEEMLLVLEIACR 995 Query: 287 CLQIDCKRRPKMSDVVKVLE 228 CL + K RP +V LE Sbjct: 996 CLGENPKTRPTTQQLVSWLE 1015
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 72.4 bits (176), Expect = 1e-12 Identities = 50/158 (31%), Positives = 90/158 (56%), Gaps = 9/158 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMS-QVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 L++ AK++DFGL + + S Q+ T + G+ GYL PE+ T Q+ EK+DVYS GVV+ Sbjct: 705 LNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVVL 764 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV---IEIMK 300 +EVI G+ + +S +E+ +H+ + + N + ++D+ L + DV ++ + Sbjct: 765 LEVITGQPAIASSKTEK-VHISDHVRSILANGDIRGIVDQR----LRERYDVGSAWKMSE 819 Query: 299 LAMWCLQIDCKRRPKMSDVV----KVLEGTMNAESNID 198 +A+ C + +RP MS VV +++ G + + N D Sbjct: 820 IALACTEHTSAQRPTMSQVVMELKQIVYGIVTDQENYD 857
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/144 (31%), Positives = 82/144 (56%), Gaps = 5/144 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVVM 468 LD++FN+ L+DFGL +L+ + V T + GT GY+ PE+ S T K DVYSFGVV++ Sbjct: 868 LDENFNSHLADFGLARLMSPYETHVSTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLL 927 Query: 467 EVICGRKNLDTSLSE---ESIHLITLLEEKVKNAHLVD-LIDKNSNDMLAHKQDVIEIMK 300 E++ ++ +D + + I + ++ + + + + D LI ND +++ +++ Sbjct: 928 ELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIYSKEND-----KEMFRVLE 982 Query: 299 LAMWCLQIDCKRRPKMSDVVKVLE 228 +A CL + K+RP +V L+ Sbjct: 983 IACLCLSENPKQRPTTQQLVSWLD 1006
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 71.6 bits (174), Expect = 2e-12 Identities = 45/150 (30%), Positives = 87/150 (58%), Gaps = 6/150 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMS---QVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGV 477 LD D+ AK++DFG+ K+ S + ++ + G+ GY+APE++ T ++ EK+D+YSFGV Sbjct: 827 LDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGV 886 Query: 476 VVMEVICGRKNLDTSLSEESI--HLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIM 303 V++E++ G++ D+ L ++ + + T L++ L +ID + L K+++ +++ Sbjct: 887 VLLELVTGKQPTDSELGDKDMAKWVCTALDK----CGLEPVIDPKLD--LKFKEEISKVI 940 Query: 302 KLAMWCLQIDCKRRPKMSDVVKVLEGTMNA 213 + + C RP M VV +L+ A Sbjct: 941 HIGLLCTSPLPLNRPSMRKVVIMLQEVSGA 970
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 70.9 bits (172), Expect = 3e-12 Identities = 49/144 (34%), Positives = 79/144 (54%), Gaps = 5/144 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKM-RGTPGYLAPEWLTSQ-ITEKADVYSFGVVV 471 +D+D NA+++DFGL L D ++++ GT GYL PE+ +T K+DVYSFGVV+ Sbjct: 642 IDEDHNARVADFGLSILGPADSGTPLSELPAGTLGYLDPEYYRLHYLTTKSDVYSFGVVL 701 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLID---KNSNDMLAHKQDVIEIMK 300 +E++ GRK +D E +I + +K + ++D +D+ A K +I Sbjct: 702 LEILSGRKAIDMQFEEGNI--VEWAVPLIKAGDIFAILDPVLSPPSDLEALK----KIAS 755 Query: 299 LAMWCLQIDCKRRPKMSDVVKVLE 228 +A C+++ K RP M V LE Sbjct: 756 VACKCVRMRGKDRPSMDKVTTALE 779
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 69.3 bits (168), Expect = 9e-12 Identities = 47/152 (30%), Positives = 90/152 (59%), Gaps = 3/152 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD++ A++SDFG+ +L+ D V+ + GTPGY+ PE+ S + + K DVYS+GVV+ Sbjct: 1017 LDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVL 1076 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKN-SNDMLAHKQDVIEIMKLA 294 +E++ G++ D+ ++ +L+ +++ K + D+ D + A + ++++ +K+A Sbjct: 1077 LELLTGKRPTDSPDFGDN-NLVGWVKQHAK-LRISDVFDPELMKEDPALEIELLQHLKVA 1134 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNID 198 + CL RRP M V+ + + + A S ID Sbjct: 1135 VACLDDRAWRRPTMVQVMAMFK-EIQAGSGID 1165
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/163 (26%), Positives = 91/163 (55%), Gaps = 3/163 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD++ A++SDFG+ +L+ D V+ + GTPGY+ PE+ S + + K DVYS+GVV+ Sbjct: 1022 LDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVL 1081 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKN-SNDMLAHKQDVIEIMKLA 294 +E++ G++ D++ ++ +L+ ++ K + D+ D+ + + + ++++ +K+A Sbjct: 1082 LELLTGKQPTDSADFGDN-NLVGWVKLHAK-GKITDVFDRELLKEDASIEIELLQHLKVA 1139 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVATNQVNF 165 CL +RP M V+ + + + + + VNF Sbjct: 1140 CACLDDRHWKRPTMIQVMAMFKEIQAGSGMDSTSTIGADDVNF 1182
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/163 (26%), Positives = 91/163 (55%), Gaps = 3/163 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDR-DMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD++ A++SDFG+ +L+ D V+ + GTPGY+ PE+ S + + K DVYS+GVV+ Sbjct: 1022 LDENLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQSFRCSTKGDVYSYGVVL 1081 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKN-SNDMLAHKQDVIEIMKLA 294 +E++ G++ D++ ++ +L+ ++ K + D+ D+ + + + ++++ +K+A Sbjct: 1082 LELLTGKQPTDSADFGDN-NLVGWVKLHAK-GKITDVFDRELLKEDASIEIELLQHLKVA 1139 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVATNQVNF 165 CL +RP M V+ + + + + + VNF Sbjct: 1140 CACLDDRHWKRPTMIQVMAMFKEIQAGSGMDSTSTIGADDVNF 1182
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 63.2 bits (152), Expect = 7e-10 Identities = 40/143 (27%), Positives = 79/143 (55%), Gaps = 4/143 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPE-WLTSQITEKADVYSFGVVVM 468 +DD F A+L++FGL K++ + ++ + + GY APE + ++DVY+FG++++ Sbjct: 508 VDDFFFARLTEFGLDKIMVQAVADEIVSQAKSDGYKAPELHKMKKCNPRSDVYAFGILLL 567 Query: 467 EVICGRKNLDTSLS-EESIHLITLLEEKVKNAHLVDLIDKNSNDMLAH--KQDVIEIMKL 297 E++ G+K + + E + L +L++ V +++ D + + ++ ++ +KL Sbjct: 568 EILMGKKPGKSGRNGNEFVDLPSLVKAAVLEETTMEVFDLEAMKGIRSPMEEGLVHALKL 627 Query: 296 AMWCLQIDCKRRPKMSDVVKVLE 228 AM C RP M +VVK LE Sbjct: 628 AMGCCAPVTTVRPSMEEVVKQLE 650
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 56.6 bits (135), Expect = 6e-08 Identities = 41/143 (28%), Positives = 74/143 (51%), Gaps = 4/143 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVV--TKMRGTPGYLAPEWLT-SQITEKADVYSFGVV 474 LD K+ DFGL + + + VV K+ GT YL PE+ Q++ DVYSFG+V Sbjct: 354 LDQCLQPKIGDFGLVREGPKSLDAVVEVNKVFGTKIYLPPEFRNFRQLSTGVDVYSFGIV 413 Query: 473 VMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV-IEIMKL 297 ++EV GR+ D E+ + ++ + ++L++K+ + + D+ + ++ Sbjct: 414 LLEVFTGRQVTDRVPENETKKNLLDYVKQQWRQNRMELLEKHLAAPMGKELDMCMCAIEA 473 Query: 296 AMWCLQIDCKRRPKMSDVVKVLE 228 + C +D + RP M+ V+K E Sbjct: 474 GLHCTALDPQDRPSMNAVLKRFE 496
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/137 (27%), Positives = 66/137 (48%), Gaps = 2/137 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVM 468 L+ D N K++DFG C I+ S+ +T M GTP ++APE ++ + K DV+S G++++ Sbjct: 1081 LNMDGNIKITDFGFCAQINEINSKRIT-MVGTPYWMAPEIVSRKEYGPKVDVWSLGIMII 1139 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV-IEIMKLAM 291 E++ G +++LI N L + + +I K Sbjct: 1140 EMLEGEPPYLNETPLRALYLIAT----------------NGTPKLKDPESLSYDIRKFLA 1183 Query: 290 WCLQIDCKRRPKMSDVV 240 WCLQ+D +R +++ Sbjct: 1184 WCLQVDFNKRADADELL 1200
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 51.6 bits (122), Expect = 2e-06 Identities = 47/151 (31%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVMEVICGR- 450 K+ DFGL DMS T M+GT Y+APE + + T K DVYSFG+++ E++ + Sbjct: 149 KICDFGLAT----DMSNNKTDMQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQL 204 Query: 449 --KNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIE-IMKLAMWCLQ 279 +L+ S+ +I EK+ M A + D E I +L C+ Sbjct: 205 PYSHLENPNSQYAIMKAISSGEKL--------------PMEAVRSDCPEGIKQLMECCMD 250 Query: 278 IDCKRRPKMSDVVKVLEGTMNAESNIDHNFV 186 I+ ++RP M ++ K L ES D +F+ Sbjct: 251 INPEKRPSMKEIEKFL--GEQYESGTDEDFI 279
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 51.6 bits (122), Expect = 2e-06 Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 7/145 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 +D+ FN K++DFG ++ ++ + +T+ GTP + APE + + EKADV+SFGVV+ Sbjct: 1495 VDEHFNVKIADFGFARI--KEDNTTMTRC-GTPCWTAPEVIRGEKYCEKADVFSFGVVMW 1551 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVI------EI 306 EV+ G+ E + + K S D+L + +I E Sbjct: 1552 EVLTGK-------------------EPFAECNFM----KVSLDILEGGRPIIPSDCPHEF 1588 Query: 305 MKLAMWCLQIDCKRRPKMSDVVKVL 231 KL C +RP M++VV+ L Sbjct: 1589 AKLIKKCWHAKAHKRPTMTEVVQQL 1613 Score = 43.5 bits (101), Expect = 5e-04 Identities = 40/173 (23%), Positives = 79/173 (45%), Gaps = 4/173 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKL-IDRDMSQVVTKMRGTPGYLAPEWLTSQITEK---ADVYSFGV 477 LD +N K+SDFGL K+ + D + + GT ++APE L ADVYSFG+ Sbjct: 916 LDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGI 975 Query: 476 VVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKL 297 ++ E++ R+ ++ +I ++++ + ++ + + +S IE + L Sbjct: 976 ILWELLT-REQPYKGMTPAAI-AVSVIRDGMRPPISDEAVTAHS----------IEYIDL 1023 Query: 296 AMWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVATNQVNFGAAANVLSS 138 C D RP +++ L + SN+ +++ + G ++ S Sbjct: 1024 IKQCWHSDTIIRPTFLEIMTRLSNILGDSSNMTSGTSSSSLSSGGIGKSITDS 1076
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK +D + + T GTP YLAPE L +A D + GVV+ Sbjct: 282 LDKDGHIKITDFGLCKEGIKDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 340 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E+ LI L+EE Sbjct: 341 EMMCGRLPFYNQDHEKLFELI-LMEE 365
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK +D + + T GTP YLAPE L +A D + GVV+ Sbjct: 282 LDKDGHIKITDFGLCKEGIKDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 340 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E+ LI L+EE Sbjct: 341 EMMCGRLPFYNQDHEKLFELI-LMEE 365
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK +D + + T GTP YLAPE L +A D + GVV+ Sbjct: 282 LDKDGHIKITDFGLCKEGIKDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 340 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E+ LI L+EE Sbjct: 341 EMMCGRLPFYNQDHEKLFELI-LMEE 365
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK +D + + T GTP YLAPE L +A D + GVV+ Sbjct: 282 LDKDGHIKITDFGLCKEGIKDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 340 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E+ LI L+EE Sbjct: 341 EMMCGRLPFYNQDHEKLFELI-LMEE 365
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD+D +SDFGL K+ D V++ GTPGY+APE L + KA D +S GV+ Sbjct: 152 LDEDSKIMISDFGLSKM--EDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAY 209 Query: 467 EVICG 453 ++CG Sbjct: 210 ILLCG 214
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD+D +SDFGL K+ D V++ GTPGY+APE L + KA D +S GV+ Sbjct: 152 LDEDSKIMISDFGLSKM--EDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAY 209 Query: 467 EVICG 453 ++CG Sbjct: 210 ILLCG 214
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK +D + + T GTP YLAPE L +A D + GVV+ Sbjct: 303 LDKDGHIKITDFGLCKEGIKDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 361 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E+ LI L+EE Sbjct: 362 EMMCGRLPFYNQDHEKLFELI-LMEE 386
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/86 (41%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK +D + + T GTP YLAPE L +A D + GVV+ Sbjct: 283 LDKDGHIKITDFGLCKEGIKDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 341 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E+ LI L+EE Sbjct: 342 EMMCGRLPFYNQDHEKLFELI-LMEE 366
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/65 (43%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD+D +SDFGL K+ D V++ GTPGY+APE L + KA D +S GV+ Sbjct: 152 LDEDSKIMISDFGLSKM--EDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAY 209 Query: 467 EVICG 453 ++CG Sbjct: 210 ILLCG 214
>KCC1_EMENI (Q00771) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CMPK) Length = 414 Score = 50.8 bits (120), Expect = 3e-06 Identities = 40/141 (28%), Positives = 70/141 (49%), Gaps = 6/141 (4%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVME 465 D D L+DFG+ K++D ++V+T M G+ GY APE + Q KA D++S GV+ Sbjct: 154 DLDSQLVLADFGIAKMLDNP-AEVLTSMAGSFGYAAPEVMLKQGHGKAVDIWSLGVITYT 212 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDK-NSNDMLAHKQDVIEIMKLA-- 294 ++CG ++ +L DLI++ S ++ H++ ++ K A Sbjct: 213 LLCG-------------------YSPFRSENLTDLIEECRSGRVVFHERYWKDVSKDAKD 253 Query: 293 --MWCLQIDCKRRPKMSDVVK 237 + LQ+D +RP + +K Sbjct: 254 FILSLLQVDPAQRPTSEEALK 274
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 50.4 bits (119), Expect = 4e-06 Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 2/77 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVV 471 +DDD +L DFGL K + D + K+ GT Y+APE + + + +AD+YS GV++ Sbjct: 252 VDDDRQVRLMDFGLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLDGRADLYSLGVIL 311 Query: 470 MEVICGRKNLDTSLSEE 420 E++ GR D E Sbjct: 312 YELLSGRPPFDAKTPHE 328
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 50.1 bits (118), Expect = 6e-06 Identities = 36/128 (28%), Positives = 66/128 (51%), Gaps = 4/128 (3%) Frame = -2 Query: 626 AKLSDFGLCKLIDRDMSQVVTKMR---GTPGYLAPEWLT-SQITEKADVYSFGVVVMEVI 459 A+L DFG+ +L++ D + V+++ GTP YL+PE +++ ++D+YSFGV+ V+ Sbjct: 152 ARLLDFGIARLVEPDAASSVSQIGVVLGTPEYLSPEQAVGAKVDTRSDLYSFGVLTYRVL 211 Query: 458 CGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWCLQ 279 GR D L L + A L +D+ + + + + ++ L M L+ Sbjct: 212 SGRLPFDGPLPR------NFLSQHASAAPLP--LDRAAPTLSRY----VGLLSLVMRLLE 259 Query: 278 IDCKRRPK 255 D +RP+ Sbjct: 260 KDASKRPQ 267
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 2/106 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQ-ITEKADVYSFGVVV 471 LD D + K++DFG+CK + + T GTP Y+APE L Q D +SFGV++ Sbjct: 512 LDKDGHIKIADFGMCK--ENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLL 569 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML 333 E++ G+ EE H I ++ N ++K + D+L Sbjct: 570 YEMLIGQSPFHGQDEEELFHSI-----RMDNPFYPRWLEKEAKDLL 610
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 49.7 bits (117), Expect = 7e-06 Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 10/114 (8%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI-TEKADVYSFGVVVM 468 LD D + KL+DFG+ K + + + GTP Y++PE + Q+ E D +SFGV++ Sbjct: 507 LDCDGHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMY 566 Query: 467 EVICGR---------KNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML 333 E++ G+ + D+ L+E T+ +E K L L D+N N L Sbjct: 567 EMLVGQSPFHGEGEDELFDSILNERPYFPKTISKEAAK--CLSALFDRNPNTRL 618
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 49.7 bits (117), Expect = 7e-06 Identities = 34/87 (39%), Positives = 47/87 (54%), Gaps = 1/87 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK D + + T GTP YLAPE L +A D + GVV+ Sbjct: 279 LDKDGHIKITDFGLCKEGITDAATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 337 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEK 387 E++CGR E+ LI + + K Sbjct: 338 EMMCGRLPFYNQDHEKLFELILMEDIK 364
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 49.7 bits (117), Expect = 7e-06 Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 2/106 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQ-ITEKADVYSFGVVV 471 LD D + K++DFG+CK + + T GTP Y+APE L Q D +SFGV+V Sbjct: 512 LDRDGHIKIADFGMCK--ENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLV 569 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML 333 E++ G+ EE H I ++ N +++ + D+L Sbjct: 570 YEMLIGQSPFHGQDEEELFHSI-----RMDNPFYPRWLEREAKDLL 610
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 49.7 bits (117), Expect = 7e-06 Identities = 34/87 (39%), Positives = 47/87 (54%), Gaps = 1/87 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK D + + T GTP YLAPE L +A D + GVV+ Sbjct: 279 LDKDGHIKITDFGLCKEGITDAATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 337 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEK 387 E++CGR E+ LI + + K Sbjct: 338 EMMCGRLPFYNQDHEKLFELILMEDIK 364
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 49.7 bits (117), Expect = 7e-06 Identities = 34/87 (39%), Positives = 47/87 (54%), Gaps = 1/87 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK D + + T GTP YLAPE L +A D + GVV+ Sbjct: 279 LDKDGHIKITDFGLCKEGITDAATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 337 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEK 387 E++CGR E+ LI + + K Sbjct: 338 EMMCGRLPFYNQDHEKLFELILMEDIK 364
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 49.3 bits (116), Expect = 1e-05 Identities = 36/86 (41%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK D + + T GTP YLAPE L +A D + GVV+ Sbjct: 288 LDKDGHVKITDFGLCKEGITDGATMRT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 346 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E LI L+EE Sbjct: 347 EMMCGRLPFYNQDHERLFELI-LMEE 371
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 49.3 bits (116), Expect = 1e-05 Identities = 36/86 (41%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK D + + T GTP YLAPE L +A D + GVV+ Sbjct: 283 LDKDGHIKITDFGLCKEGISDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 341 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E LI L+EE Sbjct: 342 EMMCGRLPFYNQDHERLFELI-LMEE 366
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 49.3 bits (116), Expect = 1e-05 Identities = 36/86 (41%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK D + + T GTP YLAPE L +A D + GVV+ Sbjct: 283 LDKDGHIKITDFGLCKEGISDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 341 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E LI L+EE Sbjct: 342 EMMCGRLPFYNQDHERLFELI-LMEE 366
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 49.3 bits (116), Expect = 1e-05 Identities = 36/86 (41%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGLCK D + + T GTP YLAPE L +A D + GVV+ Sbjct: 287 LDKDGHVKITDFGLCKEGITDGATMRT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 345 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E LI L+EE Sbjct: 346 EMMCGRLPFYNQDHERLFELI-LMEE 370
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 49.3 bits (116), Expect = 1e-05 Identities = 43/123 (34%), Positives = 59/123 (47%), Gaps = 10/123 (8%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVVM 468 LD D + K++DFGLCK D + GTP YLAPE L + + D + GVV+ Sbjct: 397 LDKDGHIKVADFGLCK-EDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMY 455 Query: 467 EVICGR--------KNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML-AHKQDV 315 E+ICGR L T + E + + ++ KN L L+ K+ L K DV Sbjct: 456 EMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNL-LAGLLAKDPKKRLGGGKDDV 514 Query: 314 IEI 306 EI Sbjct: 515 KEI 517
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 49.3 bits (116), Expect = 1e-05 Identities = 45/148 (30%), Positives = 66/148 (44%), Gaps = 7/148 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPG----YLAPEWLTS-QITEKADVYSF 483 LDD F KL+DF + Q T M + Y+ E++ +++ K DVYSF Sbjct: 301 LDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSF 360 Query: 482 GVVVMEVICG-RKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEI 306 G+V+MEV+ G R LD + L+ L EK + +DK + ++ Sbjct: 361 GIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPP--CPRNFSAKL 418 Query: 305 MKLAMWCLQIDCKRRPKMSDVVKVLEGT 222 LA C K RP M +V+ LE T Sbjct: 419 FCLAGRCAATRAKLRPSMDEVLNTLEST 446
>RIPK5_XENTR (Q67E00) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 918 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/144 (28%), Positives = 63/144 (43%), Gaps = 1/144 (0%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE + + DVY+FG++ Sbjct: 776 LDKKHRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFSGKYDNSVDVYAFGILFWY 831 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSN-DMLAHKQDVIEIMKLAMW 288 + G S+ L E+ HL + + K + + LA + E KL Sbjct: 832 ICSG-----------SVKLPEAFEKCASKDHLWNNVRKGARPERLAIFDE--ECWKLMEA 878 Query: 287 CLQIDCKRRPKMSDVVKVLEGTMN 216 C D +RP M V +L+G M+ Sbjct: 879 CWNGDPSQRPLMGIVQPMLQGIMD 902
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/90 (34%), Positives = 44/90 (48%), Gaps = 1/90 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 LD D + K++DFGLCK + + GTP YLAPE + D + GVV+ Sbjct: 311 LDRDGHIKITDFGLCKE-EIKYGDKTSTFCGTPEYLAPEVIEDIDYDRSVDWWGVGVVMY 369 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKN 378 E++CGR + + LIT + K N Sbjct: 370 EMMCGRLPFSAKENGKLFELITTCDLKFPN 399
>PMYT1_DROME (Q9NI63) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) (dMyt1) Length = 533 Score = 48.1 bits (113), Expect = 2e-05 Identities = 24/62 (38%), Positives = 37/62 (59%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEV 462 +DD KL+DFGL +DR S T+ G Y+APE L ++ AD++S G+ ++E+ Sbjct: 234 EDDETCKLADFGLVIDVDRANSHHATE--GDSRYMAPEILQGHFSKAADIFSLGIAMLEL 291 Query: 461 IC 456 C Sbjct: 292 AC 293
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 48.1 bits (113), Expect = 2e-05 Identities = 45/174 (25%), Positives = 76/174 (43%), Gaps = 34/174 (19%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKL-----IDRDMSQVVTK---MRGTPGYLAPEWL-TSQITEKADV 492 LD+ KL DFGL + S V + +RGT YL E++ T ++ D Sbjct: 348 LDERLMPKLGDFGLARFSRFAGAKASQSSTVARTSTVRGTLAYLPEEYIKTGRLAVDTDT 407 Query: 491 YSFGVVVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHL------------------- 369 +SFGVV++E + G++ + T ++ +L L+E++ + A + Sbjct: 408 FSFGVVILETLAGQRAVRTQ-GAKTKYLKDLIEDEAEEAGVTLKSTQPTLWVGVATDAWA 466 Query: 368 ----VDLIDK--NSNDMLAHKQDVIEIMKLAMWCLQIDCKRRPKMSDVVKVLEG 225 + K +S Q + + +LA C+ K+RP M+ V K LEG Sbjct: 467 APIAAQIYKKHLDSRPGPCPPQLGLALAQLACCCMHRRAKKRPPMTQVYKRLEG 520
>FUSED_DROME (P23647) Serine/threonine-protein kinase fused (EC 2.7.11.1)| Length = 805 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 1/87 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 LD + +AKL DFGL + + + V+T ++GTP Y+APE L Q AD++S G + Sbjct: 133 LDKNMHAKLCDFGLARNMTLG-THVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAY 191 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEK 387 E + G+ S +HL+ +++ + Sbjct: 192 ESMAGQPPFCAS---SILHLVKMIKHE 215
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 LD D + K++DFG+CK S+ T GTP Y+APE L + T D +SFGV++ Sbjct: 481 LDRDGHIKIADFGMCKENIFGESRAST-FCGTPDYIAPEILQGLKYTFSVDWWSFGVLLY 539 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML 333 E++ G+ +E I +V H I K S D+L Sbjct: 540 EMLIGQSPFHGDDEDELFESI-----RVDTPHYPRWITKESKDIL 579
>RIPK5_XENLA (Q67E01) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 916 Score = 48.1 bits (113), Expect = 2e-05 Identities = 40/143 (27%), Positives = 60/143 (41%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE + + DVY+FG++ Sbjct: 774 LDKKHRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFSGKYDNSVDVYAFGILFWY 829 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 + G S+ L E+ HL + + K + D E KL C Sbjct: 830 ICSG-----------SVKLPEAFEKCASKDHLWNNVRKGARPERLTIFDE-ECWKLMEAC 877 Query: 284 LQIDCKRRPKMSDVVKVLEGTMN 216 D +RP M V +L+G M+ Sbjct: 878 WNGDPSQRPLMGIVQPMLQGIMD 900
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 47.8 bits (112), Expect = 3e-05 Identities = 43/149 (28%), Positives = 68/149 (45%), Gaps = 8/149 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPG------YLAPEWLTS-QITEKADVYS 486 LDD KL+DF ++ Q + + T G Y+ E++ +++ K DVYS Sbjct: 314 LDDQLQPKLTDFAAAHFRP-NLEQQSSTINMTGGGRKHLWYMPEEYIRQGRLSVKTDVYS 372 Query: 485 FGVVVMEVICGRK-NLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIE 309 FG+V+MEV+ G K LD + L+ L EK + +D+ + + Sbjct: 373 FGIVIMEVLTGCKVVLDDPKHVQLRDLLMELMEKRGLDSCLSFLDRKIPP--CPRNFSAK 430 Query: 308 IMKLAMWCLQIDCKRRPKMSDVVKVLEGT 222 + LA C+ K RP M +V+ LE T Sbjct: 431 LFSLAGRCVATKAKLRPTMDEVLSSLEST 459
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/159 (28%), Positives = 69/159 (43%), Gaps = 10/159 (6%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMR---GTPGYLAPEWLTS--QITEKADVYSFG 480 LD DFN KLSDFG K RD + + + G+ Y APE L S + D++S G Sbjct: 144 LDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLG 203 Query: 479 VVVMEVICGRKNLDTS-----LSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV 315 V++ ++CG D S L + H + K DLI + ++ + + Sbjct: 204 VILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHI 263 Query: 314 IEIMKLAMWCLQIDCKRRPKMSDVVKVLEGTMNAESNID 198 EI+ + W LQ + + + EG AE +D Sbjct: 264 DEILSHS-W-LQPPKPKATSSASFKREGEGKYRAECKLD 300
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D K++DFGL K Q + GTP Y+APE LT + T K D++S GV++ + Sbjct: 358 DIQVKIADFGLAKFTGE--MQFTNTLCGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCL 415 Query: 458 CGRKNLDTSLSEESI 414 CG L S+ Sbjct: 416 CGFPPFSDQLGPPSL 430
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 47.8 bits (112), Expect = 3e-05 Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 34/173 (19%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLI-----DRDMSQVVTK---MRGTPGYLAPEWL-TSQITEKADV 492 LD+ KL DFGL + S +V + +RGT YL E++ T ++ D Sbjct: 348 LDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDT 407 Query: 491 YSFGVVVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSND--------- 339 +SFGVVV+E + G++ + T + +L L+EE+ + A + +++ Sbjct: 408 FSFGVVVLETLAGQRAVKTH-GARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWA 466 Query: 338 ----MLAHKQDV------------IEIMKLAMWCLQIDCKRRPKMSDVVKVLE 228 M +K+ + + + +LA CL KRRP M+ V + LE Sbjct: 467 APIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLE 519
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 1/105 (0%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 LD D + K++DFG+CK Q T GTP Y+APE L + + D +SFGV++ Sbjct: 479 LDQDGHIKIADFGMCKENIFGEKQAST-FCGTPDYIAPEILQGLKYSFSVDWWSFGVLLY 537 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML 333 E++ G+ +E I +V H I K S D+L Sbjct: 538 EMLIGQSPFHGDDEDELFESI-----RVDTPHYPRWITKESKDIL 577
>SHK2_SCHPO (Q10056) Serine/threonine-protein kinase shk2 (EC 2.7.11.1)| Length = 589 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/106 (30%), Positives = 57/106 (53%), Gaps = 2/106 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVVM 468 LD+ N K++DFG C + ++ VT M GTP ++APE + ++ K D++S G++++ Sbjct: 442 LDNSGNIKITDFGFCARLSNRTNKRVT-MVGTPYWMAPEVVKQNEYGTKVDIWSLGIMII 500 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEK-VKNAHLVDLIDKNSNDML 333 E+I +N L E+ I + L+ + +L+ KN L Sbjct: 501 EMI---ENEPPYLREDPIRALYLIAKNGTPTLKKPNLVSKNLKSFL 543
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 47.4 bits (111), Expect = 4e-05 Identities = 32/83 (38%), Positives = 51/83 (61%), Gaps = 11/83 (13%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR--GTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 K+SDFG K ++S TKM GT +LAPE + ++ ++EK D++SFGVV+ E++ G Sbjct: 294 KISDFGTSK----ELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTG 349 Query: 452 R---KNLDTS-----LSEESIHL 408 K++D+S + S+HL Sbjct: 350 EIPYKDVDSSAIIWGVGSNSLHL 372
>RIPK5_HUMAN (Q6XUX3) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase) Length = 929 Score = 47.0 bits (110), Expect = 5e-05 Identities = 39/143 (27%), Positives = 59/143 (41%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE T + DVY+FG++ Sbjct: 785 LDKQNRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFTGKYDNSVDVYAFGILFWY 840 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 + G S+ L E HL + + + + D E +L C Sbjct: 841 ICSG-----------SVKLPEAFERCASKDHLWNNVRRGARPERLPVFDE-ECWQLMEAC 888 Query: 284 LQIDCKRRPKMSDVVKVLEGTMN 216 D +RP + V +L+G MN Sbjct: 889 WDGDPLKRPLLGIVQPMLQGIMN 911
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 46.6 bits (109), Expect = 6e-05 Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 2/83 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD D + K++DFG+CK + + TK GTP Y+APE + Q K+ D +++GV++ Sbjct: 482 LDADGHVKIADFGMCK--ENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLL 539 Query: 470 MEVICGRKNLDTSLSEESIHLIT 402 E++ G+ D EE IT Sbjct: 540 YEMLVGQPPFDGEDEEELFAAIT 562
>CLA4_ASHGO (Q9HFW2) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 793 Score = 46.6 bits (109), Expect = 6e-05 Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 3/138 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLC-KLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVV 471 LD K++DFG C KL D+ + M GTP ++APE + + EK DV+S G++ Sbjct: 652 LDTHGRVKITDFGFCAKLTDKRSKRAT--MVGTPYWMAPEVVKQREYDEKVDVWSLGIMT 709 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV-IEIMKLA 294 +E++ G L EE +K + LI N L H + + +EI + Sbjct: 710 IEMLEGEPPY-------------LNEEPLKALY---LIATNGTPKLKHPELLSLEIKRFL 753 Query: 293 MWCLQIDCKRRPKMSDVV 240 CL +D + R +++ Sbjct: 754 SVCLCVDVRYRASTEELL 771
>CLA4_YEAST (P48562) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 842 Score = 46.6 bits (109), Expect = 6e-05 Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 2/137 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 LD K++DFG C + S+ T M GTP ++APE + + EK DV+S G++ + Sbjct: 701 LDTRARVKITDFGFCARLTDKRSKRAT-MVGTPYWMAPEVVKQREYDEKIDVWSLGIMTI 759 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV-IEIMKLAM 291 E++ G L E+ +K + LI N L H + + +EI + Sbjct: 760 EMLEGEPPY-------------LNEDPLKALY---LIATNGTPKLKHPESLSLEIKRFLS 803 Query: 290 WCLQIDCKRRPKMSDVV 240 CL +D + R +++ Sbjct: 804 VCLCVDVRYRASTEELL 820
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 46.6 bits (109), Expect = 6e-05 Identities = 25/77 (32%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 L++D K+ DFGL ++ D + T + GTP Y+APE L+ + + + DV+S G ++ Sbjct: 184 LNEDLEVKIGDFGLATKVEYDGERKKT-LCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMY 242 Query: 467 EVICGRKNLDTSLSEES 417 ++ G+ +TS +E+ Sbjct: 243 TLLVGKPPFETSCLKET 259
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/83 (37%), Positives = 51/83 (61%), Gaps = 11/83 (13%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR--GTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 K+SDFG K ++S TKM GT ++APE + ++ ++EK D++SFGVV+ E++ G Sbjct: 284 KISDFGTSK----ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 339 Query: 452 R---KNLDTS-----LSEESIHL 408 K++D+S + S+HL Sbjct: 340 EIPYKDVDSSAIIWGVGSNSLHL 362
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/83 (37%), Positives = 51/83 (61%), Gaps = 11/83 (13%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR--GTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 K+SDFG K ++S TKM GT ++APE + ++ ++EK D++SFGVV+ E++ G Sbjct: 284 KISDFGTSK----ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 339 Query: 452 R---KNLDTS-----LSEESIHL 408 K++D+S + S+HL Sbjct: 340 EIPYKDVDSSAIIWGVGSNSLHL 362
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 46.6 bits (109), Expect = 6e-05 Identities = 41/148 (27%), Positives = 66/148 (44%), Gaps = 6/148 (4%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ------ITEKADVYSFGV 477 +DF K+ DFG+ RD+ + +G G L W++ + T +DV+SFGV Sbjct: 418 EDFTVKIGDFGMT----RDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV 473 Query: 476 VVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKL 297 V+ E+ + LS E + V L+D D N DML E+M++ Sbjct: 474 VLWEIATLAEQPYQGLSNEQVLRF------VMEGGLLDKPD-NCPDML------FELMRM 520 Query: 296 AMWCLQIDCKRRPKMSDVVKVLEGTMNA 213 C Q + K RP +++ ++ M A Sbjct: 521 ---CWQYNPKMRPSFLEIISSVKDEMEA 545
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/83 (37%), Positives = 51/83 (61%), Gaps = 11/83 (13%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR--GTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 K+SDFG K ++S TKM GT ++APE + ++ ++EK D++SFGVV+ E++ G Sbjct: 251 KISDFGTSK----ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 306 Query: 452 R---KNLDTS-----LSEESIHL 408 K++D+S + S+HL Sbjct: 307 EIPYKDVDSSAIIWGVGSNSLHL 329
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 46.6 bits (109), Expect = 6e-05 Identities = 31/83 (37%), Positives = 51/83 (61%), Gaps = 11/83 (13%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR--GTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 K+SDFG K ++S TKM GT ++APE + ++ ++EK D++SFGVV+ E++ G Sbjct: 294 KISDFGTSK----ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG 349 Query: 452 R---KNLDTS-----LSEESIHL 408 K++D+S + S+HL Sbjct: 350 EIPYKDVDSSAIIWGVGSNSLHL 372
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 46.6 bits (109), Expect = 6e-05 Identities = 39/144 (27%), Positives = 72/144 (50%), Gaps = 15/144 (10%) Frame = -2 Query: 644 LDDDFNAKLSDFGLC------KLID------RDMSQVVTKMRGTPGYLAPEWLT---SQI 510 +D+DF+ K++D GL KL + R++ K GT Y+APE L ++ Sbjct: 146 VDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKP 205 Query: 509 TEKADVYSFGVVVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLA 330 TEK+DVYSF VV+ + ++ + ++ E+ + + +K+ + D+ D Sbjct: 206 TEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMC------IKSGNRPDVDDITE----Y 255 Query: 329 HKQDVIEIMKLAMWCLQIDCKRRP 258 +++I +MKL C + + + RP Sbjct: 256 CPREIISLMKL---CWEANPEARP 276
>LOK_DROME (O61267) Ovarian-specific serine/threonine-protein kinase Lok (EC| 2.7.11.1) (Protein loki) (dMNK) Length = 476 Score = 46.2 bits (108), Expect = 8e-05 Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 4/67 (5%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS----QITEKADVYSFGVV 474 D++ K+SDFGL K + +D V+ + GTP Y+APE L + T+K D++S GVV Sbjct: 315 DEETLLKVSDFGLSKFVQKD--SVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWSLGVV 372 Query: 473 VMEVICG 453 + + G Sbjct: 373 LFTCLSG 379
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 46.2 bits (108), Expect = 8e-05 Identities = 25/58 (43%), Positives = 39/58 (67%), Gaps = 1/58 (1%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVMEVICG 453 KL+DFG C ID +M++ T M GTP ++APE +T + K DV+S G++ +E++ G Sbjct: 520 KLTDFGFCAQIDSNMTKRTT-MVGTPYWMAPEVVTRKEYGFKVDVWSLGIMAIEMVEG 576
>PAK6_HUMAN (Q9NQU5) Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1)| (p21-activated kinase 6) (PAK-6) (PAK-5) Length = 681 Score = 46.2 bits (108), Expect = 8e-05 Identities = 30/95 (31%), Positives = 52/95 (54%), Gaps = 5/95 (5%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVMEVI 459 D KLSDFG C I +D+ + + GTP ++APE ++ S + D++S G++V+E++ Sbjct: 537 DGRVKLSDFGFCAQISKDVPK-RKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMV 595 Query: 458 CGRKNLDTSLSEESIHLITLLEE----KVKNAHLV 366 G S+ + + L + K+KN+H V Sbjct: 596 DGE---PPYFSDSPVQAMKRLRDSPPPKLKNSHKV 627
>GRK7_HUMAN (Q8WTQ7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 5/96 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEK--ADVYSFGVVV 471 LDD N +LSD GL ++ + +T+ GT GY+APE L +++ D ++ G + Sbjct: 324 LDDLGNCRLSDLGLA--VEMKGGKPITQRAGTNGYMAPEILMEKVSYSYPVDWFAMGCSI 381 Query: 470 MEVICGR---KNLDTSLSEESIHLITLLEEKVKNAH 372 E++ GR K+ +S+E + T L+++VK H Sbjct: 382 YEMVAGRTPFKDYKEKVSKEDLKQRT-LQDEVKFQH 416
>FIN1_SCHPO (O13839) G2-specific protein kinase fin1 (EC 2.7.11.1)| Length = 722 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/63 (41%), Positives = 43/63 (68%), Gaps = 2/63 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMR-GTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD++ + KL DFGL KL+D ++V T+ GTP Y++PE + +S + K+DV++ G V+ Sbjct: 159 LDENNSVKLGDFGLSKLLDN--TRVFTQSYVGTPYYMSPEIIRSSPYSAKSDVWALGCVI 216 Query: 470 MEV 462 E+ Sbjct: 217 FEI 219
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/71 (42%), Positives = 42/71 (59%), Gaps = 5/71 (7%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMR---GTPGYLAPEWLTS--QITEKADVYSFG 480 LD + +AKL+DFGL S + R GT YLAPE L + + ++ +DVYSFG Sbjct: 151 LDLELHAKLADFGLSTFQGGSQSGSGSGSRDSGGTLAYLAPELLDNDGKASKASDVYSFG 210 Query: 479 VVVMEVICGRK 447 V+V V+ GR+ Sbjct: 211 VLVWTVLAGRE 221
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 2/71 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LDD N K++DFGL ++ D + + T G+P Y APE ++ ++ + DV+S GV++ Sbjct: 182 LDDQLNVKIADFGLSNIM-TDGNFLKTSC-GSPNYAAPEVISGKLYAGPEVDVWSSGVIL 239 Query: 470 MEVICGRKNLD 438 ++CGR D Sbjct: 240 YVMLCGRLPFD 250
>RIPK5_BOVIN (Q4TVR5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 928 Score = 45.4 bits (106), Expect = 1e-04 Identities = 38/143 (26%), Positives = 59/143 (41%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE T + DVY+FG++ Sbjct: 784 LDKQNRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFTGKYDNSVDVYAFGILFWY 839 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 + G S+ L E HL + + + + D E +L C Sbjct: 840 ICSG-----------SVKLPEAFERCASKDHLWNNVRRGARPERLPVFDE-ECWQLMEAC 887 Query: 284 LQIDCKRRPKMSDVVKVLEGTMN 216 D +RP + V +L+G M+ Sbjct: 888 WDGDPSQRPLLGIVQPMLQGIMD 910
>PKAB_STRCO (P54740) Serine/threonine protein kinase pkaB (EC 2.7.11.1)| Length = 417 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/59 (42%), Positives = 34/59 (57%), Gaps = 1/59 (1%) Frame = -2 Query: 626 AKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVMEVICG 453 A L+DFG+ KLID TK+ GTP YLAPE + A D+Y+ V+ E++ G Sbjct: 152 ALLTDFGVAKLIDTPRRTRATKIIGTPDYLAPEIVEGLPPRAAVDIYALATVLYELLAG 210
>ZYG1_CAEEL (Q9GT24) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 706 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/58 (37%), Positives = 33/58 (56%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVICGR 450 KL DFGL + R + + GTPG++AP+ + T+ ADVYS G V+ ++ R Sbjct: 150 KLGDFGLATTLGR--GETTCTIVGTPGFIAPQVYDQEYTQSADVYSLGAVLYTMLTAR 205
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEK-ADVYSFGVVVM 468 LD D + K++DFGLCK + + GTP YLAPE L + D + GVV+ Sbjct: 324 LDKDGHIKIADFGLCK-EEISFGDKTSTFCGTPEYLAPEVLDDHDYGRCVDWWGVGVVMY 382 Query: 467 EVICGR 450 E++CGR Sbjct: 383 EMMCGR 388
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/77 (35%), Positives = 46/77 (59%), Gaps = 2/77 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + M V T+ GTP Y+APE + Q K+ D +++GV++ Sbjct: 470 LDSEGHIKIADFGMCK--EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLL 527 Query: 470 MEVICGRKNLDTSLSEE 420 E++ G+ D +E Sbjct: 528 YEMLAGQPPFDGEDEDE 544
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/77 (35%), Positives = 46/77 (59%), Gaps = 2/77 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + M V T+ GTP Y+APE + Q K+ D +++GV++ Sbjct: 470 LDSEGHIKIADFGMCK--EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLL 527 Query: 470 MEVICGRKNLDTSLSEE 420 E++ G+ D +E Sbjct: 528 YEMLAGQPPFDGEDEDE 544
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/77 (35%), Positives = 46/77 (59%), Gaps = 2/77 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + M V T+ GTP Y+APE + Q K+ D +++GV++ Sbjct: 470 LDSEGHIKIADFGMCK--EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLL 527 Query: 470 MEVICGRKNLDTSLSEE 420 E++ G+ D +E Sbjct: 528 YEMLAGQPPFDGEDEDE 544
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/77 (35%), Positives = 46/77 (59%), Gaps = 2/77 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + M V T+ GTP Y+APE + Q K+ D +++GV++ Sbjct: 470 LDSEGHIKIADFGMCK--EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLL 527 Query: 470 MEVICGRKNLDTSLSEE 420 E++ G+ D +E Sbjct: 528 YEMLAGQPPFDGEDEDE 544
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 3/67 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQ-VVTKMRGTPGYLAPEWLTSQITE--KADVYSFGVV 474 +D++ N K+SDFGL L D+ ++ + GTP Y+APE L+ + E K DV+S G+V Sbjct: 153 IDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYEGAKVDVWSCGIV 212 Query: 473 VMEVICG 453 + ++ G Sbjct: 213 LFVLVAG 219
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/86 (40%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD D + K++DFGL K D + + T GTP YLAPE L +A D + GVV+ Sbjct: 283 LDKDGHIKITDFGLSKEGISDGATMKT-FCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 341 Query: 467 EVICGRKNLDTSLSEESIHLITLLEE 390 E++CGR E LI L+EE Sbjct: 342 EMMCGRLPFYNQDHERLFELI-LMEE 366
>PHKG1_RABIT (P00518) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/72 (36%), Positives = 42/72 (58%), Gaps = 8/72 (11%) Frame = -2 Query: 644 LDDDFNAKLSDFGL-CKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE-------KADVY 489 LDDD N KL+DFG C+L D + + ++ GTP YLAPE + + + + D++ Sbjct: 157 LDDDMNIKLTDFGFSCQL---DPGEKLREVCGTPSYLAPEIIECSMNDNHPGYGKEVDMW 213 Query: 488 SFGVVVMEVICG 453 S GV++ ++ G Sbjct: 214 STGVIMYTLLAG 225
>CHK1_SCHPO (P34208) Serine/threonine-protein kinase chk1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 496 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLID-RDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVM 468 LD + N K+SDFG L + S+++ G+P Y APE K DV+S G+++ Sbjct: 145 LDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQQYDGSKVDVWSCGIILF 204 Query: 467 EVICGRKNLDTSLSEESIHLI 405 ++ G D ++S +L+ Sbjct: 205 ALLLGNTPWDEAISNTGDYLL 225
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/64 (39%), Positives = 38/64 (59%), Gaps = 1/64 (1%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVME 465 D++ +SDFGL K+ + V++ GTPGY+APE L + KA D +S GV+ Sbjct: 156 DEESKIMISDFGLSKMEGK--GDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYI 213 Query: 464 VICG 453 ++CG Sbjct: 214 LLCG 217
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/64 (39%), Positives = 38/64 (59%), Gaps = 1/64 (1%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVME 465 D++ +SDFGL K+ + V++ GTPGY+APE L + KA D +S GV+ Sbjct: 156 DEESKIMISDFGLSKMEGK--GDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYI 213 Query: 464 VICG 453 ++CG Sbjct: 214 LLCG 217
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 45.1 bits (105), Expect = 2e-04 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 1/71 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVVM 468 ++D + +++DFGL K + + GT YLAPE + +Q T + D+YS G++ Sbjct: 148 INDRGHVQITDFGLAKAASQATLSSTGMLLGTAAYLAPEMIENNQATAQGDLYSVGIMAW 207 Query: 467 EVICGRKNLDT 435 E++ G+ D+ Sbjct: 208 EMLTGKVPFDS 218
>CDPK1_PLAFK (P62343) Calcium-dependent protein kinase 1 (EC 2.7.11.1) (PfCPK)| (PfCDPK1) Length = 523 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/62 (40%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMSQVVTKMR---GTPGYLAPEWLTSQITEKADVYSFGVVVMEVI 459 N K+ DFGL +D K+R GT Y+APE L + EK DV+S GV++ ++ Sbjct: 206 NIKIVDFGLSSFFSKD-----NKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCGVILYILL 260 Query: 458 CG 453 CG Sbjct: 261 CG 262
>CDPK1_PLAF7 (P62344) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 523 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/62 (40%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMSQVVTKMR---GTPGYLAPEWLTSQITEKADVYSFGVVVMEVI 459 N K+ DFGL +D K+R GT Y+APE L + EK DV+S GV++ ++ Sbjct: 206 NIKIVDFGLSSFFSKD-----NKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCGVILYILL 260 Query: 458 CG 453 CG Sbjct: 261 CG 262
>PLK1_XENTR (P62205) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/77 (31%), Positives = 45/77 (58%), Gaps = 1/77 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 L+D+ K+ DFGL ++ D + T + GTP Y+APE L + + + D++S G ++ Sbjct: 175 LNDEMEVKIGDFGLATKVEYDGERKKT-LCGTPNYIAPEVLGKKGHSFEVDIWSIGCIMY 233 Query: 467 EVICGRKNLDTSLSEES 417 ++ G+ +TS +E+ Sbjct: 234 TLLVGKPPFETSCLKET 250
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/77 (31%), Positives = 45/77 (58%), Gaps = 1/77 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 L+D+ K+ DFGL ++ D + T + GTP Y+APE L + + + D++S G ++ Sbjct: 175 LNDEMEVKIGDFGLATKVEYDGERKKT-LCGTPNYIAPEVLGKKGHSFEVDIWSIGCIMY 233 Query: 467 EVICGRKNLDTSLSEES 417 ++ G+ +TS +E+ Sbjct: 234 TLLVGKPPFETSCLKET 250
>CDPK1_PLAYO (Q7RAH3) Calcium-dependent protein kinase 1 (EC 2.7.11.1)| Length = 534 Score = 45.1 bits (105), Expect = 2e-04 Identities = 23/59 (38%), Positives = 33/59 (55%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVICG 453 N K+ DFGL +D + GT Y+APE L + EK DV+S GV++ ++CG Sbjct: 205 NIKIVDFGLSSFFSKDYK--LRDRLGTAYYIAPEVLKKKYNEKCDVWSCGVIMYILLCG 261
>RIPK5_PANTR (Q4VSN5) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/143 (26%), Positives = 59/143 (41%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE T + DVY+FG++ Sbjct: 786 LDKQNRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFTGKYDNSVDVYAFGILFWY 841 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 + G S+ L E HL + + + + D E +L C Sbjct: 842 ICSG-----------SVKLPEAFERCASKDHLWNNVRRGARPERLPVFDE-ECWQLMEAC 889 Query: 284 LQIDCKRRPKMSDVVKVLEGTMN 216 D +RP + V +L+G M+ Sbjct: 890 WDGDPLKRPLLGIVQPMLQGIMD 912
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 45.1 bits (105), Expect = 2e-04 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 5/140 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMR---GTPGYLAPEWLTS--QITEKADVYSFG 480 LD DFN KLSDF K RD S + + G+P Y APE L + D++S G Sbjct: 144 LDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLG 203 Query: 479 VVVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMK 300 V++ ++CG D S ++ + +++ H V+ S + +D+I M Sbjct: 204 VILYIMVCGSMPYDDSNIKKML--------RIQKEHRVNF--PRSKHLTGECKDLIYHM- 252 Query: 299 LAMWCLQIDCKRRPKMSDVV 240 LQ D RR + +++ Sbjct: 253 -----LQPDVNRRLHIDEIL 267
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 LD D + K++DFG+CK ++ T GTP Y+APE L + + D +SFGV++ Sbjct: 479 LDKDGHIKIADFGMCKENIFGENRAST-FCGTPDYIAPEILQGLKYSFSVDWWSFGVLLY 537 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML 333 E++ G+ +E I +V H I K S D++ Sbjct: 538 EMLIGQSPFHGDDEDELFESI-----RVDTPHYPRWITKESKDIM 577
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 L++D K+ DFGL ++ + + T + GTP Y+APE L+ + + + DV+S G ++ Sbjct: 184 LNEDLEVKIGDFGLATKVEYEGERKKT-LCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMY 242 Query: 467 EVICGRKNLDTSLSEES 417 ++ G+ +TS +E+ Sbjct: 243 TLLVGKPPFETSCLKET 259
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 45.1 bits (105), Expect = 2e-04 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 L++D K+ DFGL ++ + + T + GTP Y+APE L+ + + + DV+S G ++ Sbjct: 184 LNEDLEVKIGDFGLATKVEYEGERKKT-LCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMY 242 Query: 467 EVICGRKNLDTSLSEES 417 ++ G+ +TS +E+ Sbjct: 243 TLLVGKPPFETSCLKET 259
>RIPK5_CANFA (Q4VSN4) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 931 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/142 (26%), Positives = 58/142 (40%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE T + DVY+FG++ Sbjct: 787 LDKQNRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFTGKYDNSVDVYAFGILFWY 842 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 + G S+ L E HL + + + + D E +L C Sbjct: 843 ICSG-----------SVKLPEAFERCASKDHLWNNVRRGARPERLPVFDE-ECWQLMEAC 890 Query: 284 LQIDCKRRPKMSDVVKVLEGTM 219 D +RP + V +L+G M Sbjct: 891 WDGDPSQRPLLGIVQPMLQGIM 912
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 15/113 (13%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-------ITEKADVYS 486 + +DF+ K+SDFGL K+I + GT GYLAPE L S+ +K D++S Sbjct: 302 ITNDFHLKISDFGLAKVI-HGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWS 360 Query: 485 FGVVVMEVICGRKNLDTSLSEESIHLIT--------LLEEKVKNAHLVDLIDK 351 G V+ ++ +S + I LI+ LLE ++ +DLI++ Sbjct: 361 LGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEG-IDLINR 412
>GRK7_PIG (Q8WP15) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 5/90 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEK--ADVYSFGVVV 471 LDD N +LSD GL I + VT+ GT GY+APE L + + D ++ G + Sbjct: 324 LDDLGNCRLSDLGLAVQIQD--GKPVTQRAGTNGYMAPEILMEKASYSYPVDWFAMGCSI 381 Query: 470 MEVICGR---KNLDTSLSEESIHLITLLEE 390 E++ GR K+ +S+E + TL EE Sbjct: 382 YEMVAGRTPFKDYKEKISKEDLKQRTLKEE 411
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPE-WLTSQITEKADVYSFGVVVMEVICGR 450 KL DFG + +S VV GTP YLAPE W + +KADV+S GV++ E++ + Sbjct: 162 KLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKRYNKKADVWSLGVLLYEIMGMK 221 Query: 449 KNLDTS 432 K S Sbjct: 222 KPFSAS 227
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 44.7 bits (104), Expect = 2e-04 Identities = 27/67 (40%), Positives = 40/67 (59%), Gaps = 3/67 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLID-RDMSQVVTKMRGTPGYLAPEWLTSQITE--KADVYSFGVV 474 LD+ N K+SDFGL L D R ++ GTP Y+APE ++ + KADV+S GV+ Sbjct: 142 LDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPAYVAPEVISRNGYDGFKADVWSCGVI 201 Query: 473 VMEVICG 453 + ++ G Sbjct: 202 LFVLLAG 208
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 2/82 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + T+ GTP Y+APE + Q K+ D +SFGV++ Sbjct: 488 LDAEGHIKITDFGMCK--ENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLL 545 Query: 470 MEVICGRKNLDTSLSEESIHLI 405 E++ G+ D EE I Sbjct: 546 YEMLAGQPPFDGEDEEELFQAI 567
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 2/82 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + T+ GTP Y+APE + Q K+ D +SFGV++ Sbjct: 488 LDAEGHIKITDFGMCK--ENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLL 545 Query: 470 MEVICGRKNLDTSLSEESIHLI 405 E++ G+ D EE I Sbjct: 546 YEMLAGQPPFDGEDEEELFQAI 567
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 44.7 bits (104), Expect = 2e-04 Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 6/146 (4%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ------ITEKADVYSFGV 477 +DF K+ DFG+ RD+ + +G G L W++ + T +DV+SFGV Sbjct: 1147 EDFTVKIGDFGMT----RDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV 1202 Query: 476 VVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKL 297 V+ E+ + LS E + V L+D D N DML E+M++ Sbjct: 1203 VLWEIATLAEQPYQGLSNEQVLRF------VMEGGLLDKPD-NCPDML------FELMRM 1249 Query: 296 AMWCLQIDCKRRPKMSDVVKVLEGTM 219 C Q + K RP +++ ++ M Sbjct: 1250 ---CWQYNPKMRPSFLEIIGSIKDEM 1272
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 2/83 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 L+ D + K++DFG+CK + TK GTP Y+APE + Q K+ D +++GV++ Sbjct: 480 LERDGHIKITDFGMCK--ENIFGDATTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLL 537 Query: 470 MEVICGRKNLDTSLSEESIHLIT 402 E++ G+ D +E IT Sbjct: 538 FEMLAGQPPFDGEDEDELFTAIT 560
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 44.7 bits (104), Expect = 2e-04 Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 6/146 (4%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ------ITEKADVYSFGV 477 +DF K+ DFG+ RD+ + +G G L W++ + T +DV+SFGV Sbjct: 1146 EDFTVKIGDFGMT----RDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV 1201 Query: 476 VVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKL 297 V+ E+ + LS E + V L+D D N DML E+M++ Sbjct: 1202 VLWEIATLAEQPYQGLSNEQVLRF------VMEGGLLDKPD-NCPDML------FELMRM 1248 Query: 296 AMWCLQIDCKRRPKMSDVVKVLEGTM 219 C Q + K RP +++ ++ M Sbjct: 1249 ---CWQYNPKMRPSFLEIIGSIKDEM 1271
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 44.7 bits (104), Expect = 2e-04 Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 6/146 (4%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ------ITEKADVYSFGV 477 +DF K+ DFG+ RD+ + +G G L W++ + T +DV+SFGV Sbjct: 1145 EDFTVKIGDFGMT----RDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV 1200 Query: 476 VVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKL 297 V+ E+ + LS E + V L+D D N DML E+M++ Sbjct: 1201 VLWEIATLAEQPYQGLSNEQVLRF------VMEGGLLDKPD-NCPDML------FELMRM 1247 Query: 296 AMWCLQIDCKRRPKMSDVVKVLEGTM 219 C Q + K RP +++ ++ M Sbjct: 1248 ---CWQYNPKMRPSFLEIISSIKEEM 1270
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 44.7 bits (104), Expect = 2e-04 Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 16/170 (9%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVM 468 LD + + K++DFGLCK + GTP +LAPE LT + T D + GV++ Sbjct: 654 LDTEASVKIADFGLCK-EGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIY 712 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVD---------LIDKNSNDML-AHKQD 318 E++ G EE +++ ++V+ + L+ +N L A ++D Sbjct: 713 EMLVGESPFPGDDEEEVFD--SIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKD 770 Query: 317 VIEIMK-----LAMWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVA 183 ++ K L W +D K +P ++ E SN D F + Sbjct: 771 AEDVKKHPFFRLTDWSALLDKKVKPPFVPTIRGREDV----SNFDDEFTS 816
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 44.7 bits (104), Expect = 2e-04 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 3/139 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEK---ADVYSFGVV 474 LD +N K++DFG+ L +++ G+P Y APE + S I + +DV+S GV+ Sbjct: 164 LDHKYNIKIADFGMAAL--ETEGKLLETSCGSPHYAAPE-IVSGIPYQGFASDVWSCGVI 220 Query: 473 VMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 + ++ GR D EE ++ TLL + + K +M + + E L Sbjct: 221 LFALLTGRLPFD----EEDGNIRTLLLK----------VQKGEFEMPSDDEISREAQDLI 266 Query: 293 MWCLQIDCKRRPKMSDVVK 237 L +D +RR K D++K Sbjct: 267 RKILTVDPERRIKTRDILK 285
>RK_BOVIN (P28327) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 561 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 2/67 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITE-KADVYSFGVVV 471 LDDD N ++SD GL ++ Q TK GTPG++APE L + + D ++ GV + Sbjct: 322 LDDDGNVRISDLGLA--VELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTL 379 Query: 470 MEVICGR 450 E+I R Sbjct: 380 YEMIAAR 386
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 44.3 bits (103), Expect = 3e-04 Identities = 43/164 (26%), Positives = 75/164 (45%), Gaps = 11/164 (6%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTS---QITEKADVYSFGVV 474 D + + KL+DFGL S + + GT GYLAPE + + + +DVYSFG++ Sbjct: 151 DPELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRKASTASDVYSFGIL 210 Query: 473 VMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 + V+ GR + L E + + + L +L + + + E+M+L Sbjct: 211 MWAVLAGR---EVELPTEPSLVYEAVCNRQNRPSLAEL--PQAGPETPGLEGLKELMQL- 264 Query: 293 MWCLQIDCKRR-------PKMSDVVKVLEGTMNAESNIDHNFVA 183 C + K R PK +V +++E MNA + +F++ Sbjct: 265 --CWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVSTVKDFLS 306
>RIPK5_CHICK (Q6XUX0) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 930 Score = 44.3 bits (103), Expect = 3e-04 Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 4/154 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE T + DVY+FG++ Sbjct: 786 LDKKNRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFTGKYDNSVDVYAFGILFWY 841 Query: 464 VICGRKNLDTSLSE--ESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 + G L + HL + V+ L + D+ E +L Sbjct: 842 ICSGHVKLPEAFERCASKDHLWNNVRRGVRPERL-PVFDE-------------ECWQLME 887 Query: 290 WCLQIDCKRRPKMSDVVKVLEGTMN--AESNIDH 195 C D +RP + V +L+G M+ +S+ +H Sbjct: 888 ACWDGDSSQRPLLGIVQPMLQGIMDRLCKSSSEH 921
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 44.3 bits (103), Expect = 3e-04 Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 147 LDAQMNAKIADFGLSNMMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 ++CG +L + H+ TL +K++ V I + N +A L M Sbjct: 205 YALLCG------TLPFDDEHVPTLF-KKIRGG--VFYIPEYLNRSIA---------TLLM 246 Query: 290 WCLQIDCKRRPKMSDV 243 LQ+D +R + D+ Sbjct: 247 HMLQVDPLKRATIKDI 262
>CDPK3_PLAF7 (Q9NJU9) Calcium-dependent protein kinase 3 (EC 2.7.11.1) (PfCDPK3)| Length = 562 Score = 44.3 bits (103), Expect = 3e-04 Identities = 51/203 (25%), Positives = 86/203 (42%), Gaps = 5/203 (2%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVICGRKN 444 K+ DFGL + ++ TK GTP Y+AP+ LT K D++S GV+ ++CG Sbjct: 256 KIIDFGLASYFTHNNYEMKTKA-GTPYYVAPQVLTGSYNYKCDMWSSGVLFYILLCGY-- 312 Query: 443 LDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWCLQIDCKR 264 ES H I + +K K K N++ +D+I+ CL +D + Sbjct: 313 --PPFFGESDHEILSMVKKGK----YQFKGKEWNNISEEAKDLIK------RCLTMDADK 360 Query: 263 RPKMSDVV-----KVLEGTMNAESNIDHNFVATNQVNFGAAANVLSSVPPLASHVSGPR* 99 R S+ + K + N + +D + V N N+G + + S Sbjct: 361 RICASEALQHPWFKKKKYAFNMDMKMDIH-VLENFKNYGLLLKFQKLAMTIIAQQSNDYD 419 Query: 98 NEKILTR*LDYEQDMRYSYVKER 30 EK+ + L ++D + KE+ Sbjct: 420 VEKLKSTFLVLDEDGKGYITKEQ 442
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 1/105 (0%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 LD D + K++DFG+CK + T GTP Y+APE L + + D +SFGV++ Sbjct: 479 LDRDGHIKIADFGMCKENIFGEGRAST-FCGTPDYIAPEILQGLKYSFSVDWWSFGVLLY 537 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDML 333 E++ G+ +E I +V H I K S D++ Sbjct: 538 EMLIGQSPFHGDDEDELFESI-----RVDTPHYPRWITKESKDIM 577
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD + + K++DFG+CK S T GTP Y+APE + Q K+ D +SFGV++ Sbjct: 488 LDAEGHIKITDFGMCKENVFPGSTTRT-FCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLY 546 Query: 467 EVICGRKNLDTSLSEESIHLI 405 E++ G+ D EE I Sbjct: 547 EMLAGQPPFDGEDEEELFQAI 567
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD + + K++DFG+CK S T GTP Y+APE + Q K+ D +SFGV++ Sbjct: 488 LDAEGHIKITDFGMCKENVFPGSTTRT-FCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLY 546 Query: 467 EVICGRKNLDTSLSEESIHLI 405 E++ G+ D EE I Sbjct: 547 EMLAGQPPFDGEDEEELFQAI 567
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 44.3 bits (103), Expect = 3e-04 Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD + + K++DFG+CK S T GTP Y+APE + Q K+ D +SFGV++ Sbjct: 473 LDAEGHIKITDFGMCKENVFPGSTTRT-FCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLY 531 Query: 467 EVICGRKNLDTSLSEESIHLI 405 E++ G+ D EE I Sbjct: 532 EMLAGQPPFDGEDEEELFQAI 552
>CLA4_CANAL (O14427) Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)| Length = 971 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 2/85 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLC-KLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVV 471 LD N K++DFG C KL D+ + M GTP ++APE + + EK DV+S G++ Sbjct: 811 LDAYGNVKITDFGFCAKLTDQRNKRAT--MVGTPYWMAPEVVKQKEYDEKVDVWSLGIMT 868 Query: 470 MEVICGRKNLDTSLSEESIHLITLL 396 +E+I G L+EE + + L+ Sbjct: 869 IEMIEGE---PPYLNEEPLKALYLI 890
>RIPK5_RAT (Q6XUX2) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 927 Score = 43.9 bits (102), Expect = 4e-04 Identities = 38/143 (26%), Positives = 57/143 (39%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE T + DVY+FG++ Sbjct: 783 LDKQNRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFTGKYDNSVDVYAFGILFWY 838 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 + G SI L E HL + + + + D E +L C Sbjct: 839 ICSG-----------SIKLPEAFERCASKDHLWNNVRRGTRPERLPVFDE-ECWQLMEAC 886 Query: 284 LQIDCKRRPKMSDVVKVLEGTMN 216 D +RP + V +L M+ Sbjct: 887 WDGDPSKRPLLGIVQPILRSIMD 909
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQ-ITEKADVYSFGVVV 471 LD + + K++DFG+CK + M T+ GTP Y+APE + Q D +++GV++ Sbjct: 452 LDAEGHIKIADFGMCK--ENIMGDKTTRTFCGTPDYIAPEIVLYQPYGRSVDWWAYGVLL 509 Query: 470 MEVICGRKNLDTSLSEESIHLIT 402 E++ G+ D EE IT Sbjct: 510 YEMLAGQPPFDGEDEEELFTSIT 532
>CDPK3_PLAYO (Q7RAV5) Calcium-dependent protein kinase 3 (EC 2.7.11.1)| Length = 538 Score = 43.9 bits (102), Expect = 4e-04 Identities = 38/129 (29%), Positives = 60/129 (46%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVICGRKN 444 K+ DFGL + D+ + GTP Y+AP+ LT K D++S GV+ ++CG Sbjct: 250 KIIDFGLAAYFN-DIDYEMKTKAGTPYYVAPQVLTGCYDYKCDLWSAGVLFYIILCGY-- 306 Query: 443 LDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWCLQIDCKR 264 ES H I + +K K + K N++ +D+I+ CL ID + Sbjct: 307 --PPFYGESDHEILSMVKKGK----YNFKGKEWNNISDEAKDLIK------RCLTIDSGK 354 Query: 263 RPKMSDVVK 237 R S+ +K Sbjct: 355 RINASEALK 363
>NRKB_TRYBB (Q03428) Putative serine/threonine-protein kinase B (EC 2.7.11.1)| Length = 431 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPE-WLTSQITEKADVYSFGVVVMEVICGR 450 KL DFG + +S VV GTP YLAPE W + +KADV+S GV++ E++ + Sbjct: 162 KLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNLRYNKKADVWSLGVLLYEIMGMK 221 Query: 449 KNLDTS 432 K S Sbjct: 222 KPFSAS 227
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Frame = -2 Query: 632 FNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS--QITEKADVYSFGVVVMEVI 459 FN KL+DFG K++ + ++ G+ Y APE L ++K DV+S GVV+ ++ Sbjct: 145 FNLKLTDFGFAKVLPKSRRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVML 204 Query: 458 CGRKNLD 438 C D Sbjct: 205 CASLPFD 211
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 43.9 bits (102), Expect = 4e-04 Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 2/129 (1%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTP-GYLAPEWLTSQI-TEKADVYSFGVVVME 465 +D K++DFGL +L D + K P + APE S++ T K+DV+S+G+V+ E Sbjct: 352 NDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFE 411 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 ++ + + + + EKV + + +K + EI K+ +WC Sbjct: 412 ILTWASSPYPDIPAKEV------IEKVSKGYRMPNPEKFITGVCCPD----EIYKIMIWC 461 Query: 284 LQIDCKRRP 258 + ++RP Sbjct: 462 WDANPEKRP 470
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 2/67 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + V TK GTP Y+APE + Q K+ D ++FGV++ Sbjct: 473 LDSEGHIKIADFGMCK--ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLL 530 Query: 470 MEVICGR 450 E++ G+ Sbjct: 531 YEMLAGQ 537
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 2/67 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + V TK GTP Y+APE + Q K+ D ++FGV++ Sbjct: 473 LDSEGHIKIADFGMCK--ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLL 530 Query: 470 MEVICGR 450 E++ G+ Sbjct: 531 YEMLAGQ 537
>POLO_DROME (P52304) Serine/threonine-protein kinase polo (EC 2.7.11.21)| Length = 576 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 1/88 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 L+D + K+ DFGL I+ + + T + GTP Y+APE LT + + + D++S G V+ Sbjct: 156 LNDLLHVKIGDFGLATRIEYEGERKKT-LCGTPNYIAPEILTKKGHSFEVDIWSIGCVMY 214 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKV 384 ++ G+ +T +++ I E +V Sbjct: 215 TLLVGQPPFETKTLKDTYSKIKKCEYRV 242
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 43.9 bits (102), Expect = 4e-04 Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 9/133 (6%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVMEVICGRK 447 K++DFG+ K + M G+ YL+PE S T ++D+Y+ G+++ E++ G+ Sbjct: 151 KVTDFGIAKALSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQI 210 Query: 446 NLDTSLS--------EESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 D + +ESI I L +V A +I + D+ DV E+M Sbjct: 211 PFDGDSAVAIALKHFQESIPSIINLNPEVPQALENVVIKATAKDIKNRYTDVEEMMTDVA 270 Query: 290 WCLQIDCKRRPKM 252 +D + K+ Sbjct: 271 TSTSLDRRGEEKL 283
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVVMEVICGRK 447 K++DFG+ K +D + GT Y+APE L T +DVYS GV+ EV+ G++ Sbjct: 156 KITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDATPASDVYSLGVIGYEVVSGKR 215
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 43.9 bits (102), Expect = 4e-04 Identities = 21/57 (36%), Positives = 34/57 (59%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVICG 453 K+ DFGL K + + T GTP Y+AP+ L + +K D++S GV++ ++CG Sbjct: 209 KIIDFGLSKNLGT--GEFTTTKAGTPYYVAPQVLDGKYDKKCDIWSSGVIMYTLLCG 263
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 43.9 bits (102), Expect = 4e-04 Identities = 27/65 (41%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 LD + L DFGLCKL +D + T GTP YLAPE L Q T+ D ++ G+++ Sbjct: 475 LDYQGHIALCDFGLCKLNMKDNDKTDT-FCGTPEYLAPEILLGQGYTKTVDWWTLGILLY 533 Query: 467 EVICG 453 E++ G Sbjct: 534 EMMTG 538
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 147 LDAQMNAKIADFGLSNMMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 ++CG +L + H+ TL +K++ V I + N +A L M Sbjct: 205 YALLCG------TLPFDDEHVPTLF-KKIRGG--VFYIPEYLNRSVA---------TLLM 246 Query: 290 WCLQIDCKRRPKMSDV 243 LQ+D +R + D+ Sbjct: 247 HMLQVDPLKRATIKDI 262
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/63 (38%), Positives = 37/63 (58%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEV 462 DDD + K DFGL QV T++ G+P Y+APE L + ++DV+S GV++ + Sbjct: 215 DDDLSIKAIDFGLSVFFKP--GQVFTELVGSPYYVAPEVLHKRYGPESDVWSAGVILYVL 272 Query: 461 ICG 453 + G Sbjct: 273 LSG 275
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 43.9 bits (102), Expect = 4e-04 Identities = 22/66 (33%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 LD + + +++DFG+CKL + + GTP Y+APE + + + D +SFGV++ Sbjct: 447 LDYEGHVRIADFGMCKL-QIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLY 505 Query: 467 EVICGR 450 E++ G+ Sbjct: 506 EMLIGQ 511
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 43.9 bits (102), Expect = 4e-04 Identities = 21/57 (36%), Positives = 34/57 (59%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVICG 453 K+ DFGL K + + T GTP Y+AP+ L + +K D++S GV++ ++CG Sbjct: 209 KIIDFGLSKNLGT--GEFTTTKAGTPYYVAPQVLDGKYDKKCDIWSSGVIMYTLLCG 263
>ATG1_COLLN (P87248) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) (Colletotrichum lindemuthianum kinase 1) Length = 675 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVMEVICGRK 447 KL+DFG +++ + + + G+P Y+APE L + KAD++S G V+ E+I GR Sbjct: 211 KLADFGFARVLPS--TSLADTLCGSPLYMAPEILRYERYDAKADLWSVGTVLYEMITGRP 268 Query: 446 NLDTSLSEESIHLITLLEEKVK 381 E + I E+KVK Sbjct: 269 PFRARNHVELLRKIEATEDKVK 290
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/145 (25%), Positives = 69/145 (47%), Gaps = 3/145 (2%) Frame = -2 Query: 641 DDDFNAKLSDFGLC-KLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 ++ ++A ++DFGL K+ D + + G+P ++APE L + EKADV+S+G+++ Sbjct: 188 ENGYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILC 247 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHL-VDLIDKNSNDMLAHKQDVIEIMKLAM 291 E+I + + +L + +N L D D + + ++L Sbjct: 248 EII-------ARIQADPDYL-----PRTENFGLDYDAFQHMVGDCPS------DFLQLTF 289 Query: 290 WCLQIDCKRRPKMSDVVKVLEGTMN 216 C +D K RP ++ K LE M+ Sbjct: 290 NCCNMDPKLRPSFEEIGKTLEEIMS 314
>GRK7_SPETR (Q9Z2G7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 548 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 5/90 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEK--ADVYSFGVVV 471 LDD N +LSD GL + D + +T+ GT GY+APE L + + D ++ G + Sbjct: 319 LDDLGNCRLSDLGLAVEVQDD--KPITQRAGTNGYMAPEILMDKASYSYPVDWFAMGCSI 376 Query: 470 MEVICGR---KNLDTSLSEESIHLITLLEE 390 E++ GR K+ +S+E + T+ +E Sbjct: 377 YEMVAGRTPFKDFKEKVSKEDLKERTMKDE 406
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 2/67 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + V TK GTP Y+APE + Q K+ D ++FGV++ Sbjct: 473 LDSEGHIKIADFGMCK--ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLL 530 Query: 470 MEVICGR 450 E++ G+ Sbjct: 531 YEMLAGQ 537
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 2/67 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + V TK GTP Y+APE + Q K+ D ++FGV++ Sbjct: 473 LDSEGHIKIADFGMCK--ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLL 530 Query: 470 MEVICGR 450 E++ G+ Sbjct: 531 YEMLAGQ 537
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 43.9 bits (102), Expect = 4e-04 Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 2/67 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + K++DFG+CK + V TK GTP Y+APE + Q K+ D ++FGV++ Sbjct: 473 LDSEGHIKIADFGMCK--ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLL 530 Query: 470 MEVICGR 450 E++ G+ Sbjct: 531 YEMLAGQ 537
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 43.9 bits (102), Expect = 4e-04 Identities = 23/63 (36%), Positives = 41/63 (65%), Gaps = 2/63 (3%) Frame = -2 Query: 641 DDDFNAKLSDFGLC-KLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 ++ ++A ++DFGL K+ D M + G+P ++APE L + EKADV+S+G+++ Sbjct: 188 ENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILC 247 Query: 467 EVI 459 E+I Sbjct: 248 EII 250
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/60 (41%), Positives = 37/60 (61%), Gaps = 1/60 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI-TEKADVYSFGVVVMEVI 459 D K+SDFGL +L SQ+ T+ G Y+APE +EK+DVYS+G+V+ E++ Sbjct: 1441 DIKCKISDFGLSRLKKEQASQM-TQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELL 1499
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 43.9 bits (102), Expect = 4e-04 Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 9/105 (8%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMS--QVVTK-MRGTPGYLAPEWLTS--QITEKADVYSFG 480 LD DFN KLSDFG K RD S +++K G+ Y APE L + D++S G Sbjct: 144 LDKDFNIKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLG 203 Query: 479 VVVMEVICGRKNLDTS----LSEESIHLITLLEEKVKNAHLVDLI 357 V++ ++CG D S L + H + K DLI Sbjct: 204 VILYIMVCGSMPYDDSNIKKLRIQKEHRVNFPRSKHLTGECKDLI 248
>PAK1_CAEEL (Q17850) Serine/threonine-protein kinase pak-1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK1) (CePAK) Length = 572 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/62 (38%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVMEVI 459 D + KL+DFG C + + + T M GTP ++APE +T Q K DV+S G++ +E++ Sbjct: 425 DGSVKLTDFGFCAQLSPEQRKRTT-MVGTPYWMAPEVVTRKQYGPKVDVWSLGIMAIEMV 483 Query: 458 CG 453 G Sbjct: 484 EG 485
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 43.9 bits (102), Expect = 4e-04 Identities = 36/125 (28%), Positives = 60/125 (48%), Gaps = 10/125 (8%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 LD + + KL+DFG+CK + + T GTP Y+APE L Q D ++ GV++ Sbjct: 435 LDQEGHCKLADFGMCKEGIMN-GMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMY 493 Query: 467 EVICGR---------KNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV 315 E++ G+ + D+ + ++ ++ + L E V + L + KN L D Sbjct: 494 EMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAV--SILKGFLTKNPEQRLGCTGDE 551 Query: 314 IEIMK 300 EI K Sbjct: 552 NEIRK 556
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 43.9 bits (102), Expect = 4e-04 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 10/97 (10%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPE-WLTSQITEKADVYSFGVVVM 468 L D + K++D+GLCK D GTP ++APE L Q T D ++FGV++ Sbjct: 816 LSPDGHVKVADYGLCK-EDMWHDNTTATFCGTPEFMAPEILLEQQYTRSVDWWAFGVLIY 874 Query: 467 EVICGR---------KNLDTSLSEESIHLITLLEEKV 384 +++ G+ + D LS+E ++ I + + V Sbjct: 875 QMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMPRDSV 911
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/68 (33%), Positives = 39/68 (57%), Gaps = 2/68 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ--ITEKADVYSFGVVV 471 LD D K+SDFG+ + S MRGT ++APE + ++ + K D++S G +V Sbjct: 1311 LDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIV 1370 Query: 470 MEVICGRK 447 +E+ G++ Sbjct: 1371 LEMFAGKR 1378
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE--KADVYSFGVVV 471 LD + N K+SDFGL L + + T GTP Y+APE L+ Q + AD++S GV++ Sbjct: 142 LDTNGNLKVSDFGLSALPQEGVELLRTTC-GTPNYVAPEVLSGQGYDGSAADIWSCGVIL 200 Query: 470 MEVICG 453 ++ G Sbjct: 201 FVILAG 206
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E+I Sbjct: 400 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 458 Query: 458 CG 453 G Sbjct: 459 EG 460
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E+I Sbjct: 400 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 458 Query: 458 CG 453 G Sbjct: 459 EG 460
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 1/64 (1%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVME 465 +D + K+ DFGL ++ S + G+PGY+APE L + K D++S GV++ Sbjct: 242 NDPSSLKIIDFGLASFLN---SPSMNMRCGSPGYVAPEILKCASYGTKVDIFSLGVILFN 298 Query: 464 VICG 453 ++CG Sbjct: 299 ILCG 302
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 43.5 bits (101), Expect = 5e-04 Identities = 26/77 (33%), Positives = 46/77 (59%), Gaps = 2/77 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTK-MRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 L+ + + K++DFG+CK + M V T+ GTP Y+APE + Q K+ D +++GV++ Sbjct: 470 LNSEGHIKIADFGMCK--EHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLL 527 Query: 470 MEVICGRKNLDTSLSEE 420 E++ G+ D +E Sbjct: 528 YEMLAGQPPFDGEDEDE 544
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 2/142 (1%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVMEVICGRK 447 KL+DFG C I+ +++ T M GTP ++APE ++ + K D++S G++++E+I G Sbjct: 754 KLTDFGFCAQIN-ELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGE- 811 Query: 446 NLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM-WCLQIDC 270 L+E + + LI N L +++ +K + WCL ++ Sbjct: 812 --PPYLNETPLRALY-------------LIATNGTPKLKEPENLSSSLKKFLDWCLCVEP 856 Query: 269 KRRPKMSDVVKVLEGTMNAESN 204 + R ++++ T AE+N Sbjct: 857 EDRASATELLHDEYITEIAEAN 878
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 147 LDAHMNAKIADFGLSNIMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 ++CG +L + H+ TL +K++ V I + N +A L M Sbjct: 205 YALLCG------TLPFDDEHVPTLF-KKIRGG--VFYIPEYLNRSVA---------TLLM 246 Query: 290 WCLQIDCKRRPKMSDV 243 LQ+D +R + D+ Sbjct: 247 HMLQVDPLKRATIKDI 262
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 43.5 bits (101), Expect = 5e-04 Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 147 LDAHMNAKIADFGLSNMMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 ++CG +L + H+ TL +K++ V I + N +A L M Sbjct: 205 YALLCG------TLPFDDEHVPTLF-KKIRGG--VFYIPEYLNRSVA---------TLLM 246 Query: 290 WCLQIDCKRRPKMSDV 243 LQ+D +R + D+ Sbjct: 247 HMLQVDPLKRATIKDI 262
>TLK1_CAEEL (P34314) Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1)| (Tousled-like kinase 1) Length = 965 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 9/79 (11%) Frame = -2 Query: 623 KLSDFGLCKLI-----DRDMS-QVVTKMRGTPGYLAPEWLT---SQITEKADVYSFGVVV 471 K++DFGL K++ D D+ ++ ++ GT YL PE +IT K DV+S GV+ Sbjct: 799 KITDFGLSKIMEGESDDHDLGIELTSQFAGTYWYLPPETFIVPPPKITCKVDVWSIGVIF 858 Query: 470 MEVICGRKNLDTSLSEESI 414 + I G+K L+++ I Sbjct: 859 YQCIYGKKPFGNDLTQQKI 877
>PLK3_MOUSE (Q60806) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) Length = 631 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 + D+ K+ DFGL ++ + T + GTP Y+APE L Q +ADV+S G V+ Sbjct: 194 ITDNMELKVGDFGLAARLEPPEQRKKT-ICGTPNYVAPEVLLRQGHGPEADVWSLGCVMY 252 Query: 467 EVICGRKNLDTSLSEESIHLI 405 ++CG +T+ +E+ I Sbjct: 253 TLLCGSPPFETADLKETYRCI 273
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 43.5 bits (101), Expect = 5e-04 Identities = 22/63 (34%), Positives = 42/63 (66%), Gaps = 2/63 (3%) Frame = -2 Query: 641 DDDFNAKLSDFGLC-KLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 ++ ++A ++DFGL K+ D + + + G+P ++APE L + EKADV+S+G+++ Sbjct: 188 ENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRDEPYNEKADVFSYGIILC 247 Query: 467 EVI 459 E+I Sbjct: 248 EII 250
>PLK3_RAT (Q9R011) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Fragment) Length = 615 Score = 43.5 bits (101), Expect = 5e-04 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 + D+ K+ DFGL ++ + T + GTP Y+APE L Q +ADV+S G V+ Sbjct: 162 ITDNMELKVGDFGLAARLEPPEQRKKT-ICGTPNYVAPEVLLRQGHGPEADVWSLGCVMY 220 Query: 467 EVICGRKNLDTSLSEESIHLI 405 ++CG +T+ +E+ I Sbjct: 221 TLLCGSPPFETADLKETYRCI 241
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 43.5 bits (101), Expect = 5e-04 Identities = 24/87 (27%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI-TEKADVYSFGVVVMEV 462 + N KLSD+G+ + + + + GTPGY APE + EK D++S+G+V+ E+ Sbjct: 1401 EHINIKLSDYGISR---QSFHEGALGVEGTPGYQAPEIRPRIVYDEKVDMFSYGMVLYEL 1457 Query: 461 ICGRKNLDTSLSEESIHLITLLEEKVK 381 + G++ +L + ++ L + ++ Sbjct: 1458 LSGQR---PALGHHQLQIVKKLSKGIR 1481
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 43.5 bits (101), Expect = 5e-04 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Frame = -2 Query: 632 FNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS--QITEKADVYSFGVVVMEVI 459 FN KL+DFG K++ + ++ G+ Y APE L ++K DV+S GVV+ ++ Sbjct: 145 FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVML 204 Query: 458 CGRKNLD 438 C D Sbjct: 205 CASLPFD 211
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E+I Sbjct: 399 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 457 Query: 458 CG 453 G Sbjct: 458 EG 459
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 43.5 bits (101), Expect = 5e-04 Identities = 36/133 (27%), Positives = 66/133 (49%), Gaps = 10/133 (7%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD + + K++DFG K + V + GTP Y+APE ++++ K+ D +SFG+++ Sbjct: 218 LDKNGHIKITDFGFAKYVP----DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIY 273 Query: 467 EVICG---------RKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDV 315 E++ G K + L+ E + E VK+ L LI ++ + L + Q+ Sbjct: 274 EMLAGYTPFYDSNTMKTYEKILNAE-LRFPPFFNEDVKDL-LSRLITRDLSQRLGNLQNG 331 Query: 314 IEIMKLAMWCLQI 276 E +K W ++ Sbjct: 332 TEDVKNHPWFKEV 344
>TLK2_HUMAN (Q86UE8) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) (PKU-alpha) Length = 772 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR------GTPGYLAPEWLT-----SQITEKADVYSFGV 477 K++DFGL K++D D V M GT YL PE +I+ K DV+S GV Sbjct: 610 KITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGV 669 Query: 476 VVMEVICGRKNLDTSLSEESI 414 + + + GRK + S++ I Sbjct: 670 IFYQCLYGRKPFGHNQSQQDI 690
>PKN1_MYXXA (P33973) Serine/threonine-protein kinase pkn1 (EC 2.7.11.1)| Length = 693 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/60 (40%), Positives = 36/60 (60%), Gaps = 2/60 (3%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR-GTPGYLAPEW-LTSQITEKADVYSFGVVVMEVICGR 450 K+ DFG+ KL D M Q + GTP Y+APE L + +AD+Y+ GV+ +++ GR Sbjct: 199 KVLDFGIAKLADAHMPQTHAGIIVGTPEYMAPEQSLGRGVDGRADLYALGVIAYQLLTGR 258
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 43.1 bits (100), Expect = 7e-04 Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + KL+DFG+CK + + V T GTP Y+APE L + A D ++ GV++ Sbjct: 486 LDHEGHCKLADFGMCK--EGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLL 543 Query: 470 MEVICGRKNLDTSLSEESIHLI 405 E++CG + ++ I Sbjct: 544 YEMLCGHAPFEAENEDDLFEAI 565
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/62 (38%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ Sbjct: 398 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMV 456 Query: 458 CG 453 G Sbjct: 457 EG 458
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 43.1 bits (100), Expect = 7e-04 Identities = 45/174 (25%), Positives = 72/174 (41%), Gaps = 3/174 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ---ITEKADVYSFGVV 474 LD+ N K+ DFGL L+ D + +T + GTP Y+APE L + + + D++S GVV Sbjct: 171 LDESNNVKIGDFGLAALLMDDEERKMT-ICGTPNYIAPEILFNSKEGHSFEVDLWSAGVV 229 Query: 473 VMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 + ++ G+ +++VK + I NS ++ E L Sbjct: 230 MYALLIGKPPFQ--------------DKEVKT--IYRKIKANSYSFPSNVDISAEAKDLI 273 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVATNQVNFGAAANVLSSVP 132 L D RP + D+V DH F T + +L S+P Sbjct: 274 SSLLTHDPSIRPSIDDIV-------------DHEFFHTGYMASTLPDEILHSMP 314
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 43.1 bits (100), Expect = 7e-04 Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + KL+DFG+CK + + V T GTP Y+APE L + A D ++ GV++ Sbjct: 487 LDHEGHCKLADFGMCK--EGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLL 544 Query: 470 MEVICGRKNLDTSLSEESIHLI 405 E++CG + ++ I Sbjct: 545 YEMLCGHAPFEAENEDDLFEAI 566
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 43.1 bits (100), Expect = 7e-04 Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVT-KMRGTPGYLAPEWLTSQITEKA-DVYSFGVVV 471 LD + + KL+DFG+CK + + V T GTP Y+APE L + A D ++ GV++ Sbjct: 487 LDHEGHCKLADFGMCK--EGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLL 544 Query: 470 MEVICGRKNLDTSLSEESIHLI 405 E++CG + ++ I Sbjct: 545 YEMLCGHAPFEAENEDDLFEAI 566
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 43.1 bits (100), Expect = 7e-04 Identities = 40/138 (28%), Positives = 63/138 (45%), Gaps = 2/138 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ--ITEKADVYSFGVVV 471 + D K+ DFGL + D Q+ T G+ + APE L + + DV+SFGVV+ Sbjct: 277 ISDSSEIKIIDFGLSNIYD-SRKQLHT-FCGSLYFAAPELLKANPYTGPEVDVWSFGVVL 334 Query: 470 MEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAM 291 ++CG+ D S ++L EK+K + + H IE++ L Sbjct: 335 FVLVCGKVPFDDENS-------SVLHEKIKQGKV---------EYPQHLS--IEVISLLS 376 Query: 290 WCLQIDCKRRPKMSDVVK 237 L +D KRR + VV+ Sbjct: 377 KMLVVDPKRRATLKQVVE 394
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 43.1 bits (100), Expect = 7e-04 Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 6/147 (4%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ------ITEKADVYSFGV 477 +DF K+ DFG+ RD+ + +G G L W++ + T +DV+SFGV Sbjct: 1141 EDFTVKIGDFGMT----RDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGV 1196 Query: 476 VVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKL 297 V+ E+ + +S E + V L++ D N DML E+M++ Sbjct: 1197 VLWEIATLAEQPYQGMSNEQVLRF------VMEGGLLEKPD-NCPDML------FELMRM 1243 Query: 296 AMWCLQIDCKRRPKMSDVVKVLEGTMN 216 C Q + K RP +++ ++ ++ Sbjct: 1244 ---CWQFNPKMRPSFLEIISSIKDELD 1267
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 43.1 bits (100), Expect = 7e-04 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 5/154 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYL-APEWLTSQI--TEKADVYSFGVV 474 LDD N K++DFGL ++ D + + T G+P Y+ APE ++ ++ + DV+S GV+ Sbjct: 183 LDDQLNVKIADFGLSNIM-TDGNFLKTSC-GSPNYMPAPEVISGKLYAGPEVDVWSAGVI 240 Query: 473 VMEVICGRKNLDTSLSEESIHLITLLEEKVKNA--HLVDLIDKNSNDMLAHKQDVIEIMK 300 + ++CGR D I L +K+ N L + + + +L V + + Sbjct: 241 LYVMLCGRLPFDD-------EFIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVVNPLNR 293 Query: 299 LAMWCLQIDCKRRPKMSDVVKVLEGTMNAESNID 198 + + + D + M D + + + N S ID Sbjct: 294 ITIHEIMEDDWFKQDMPDYLLPPDLSKNKNSKID 327
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/62 (38%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ Sbjct: 413 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 Query: 458 CG 453 G Sbjct: 472 EG 473
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/62 (38%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ Sbjct: 413 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 Query: 458 CG 453 G Sbjct: 472 EG 473
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/62 (38%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ Sbjct: 413 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 Query: 458 CG 453 G Sbjct: 472 EG 473
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 43.1 bits (100), Expect = 7e-04 Identities = 24/62 (38%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVI 459 D + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ Sbjct: 413 DGSVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 Query: 458 CG 453 G Sbjct: 472 EG 473
>KCC1G_MOUSE (Q91VB2) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 43.1 bits (100), Expect = 7e-04 Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 1/64 (1%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVME 465 +++ ++DFGL K+ + + V++ GTPGY+APE L + KA D +S GV+ Sbjct: 155 EENSKIMITDFGLSKM---EQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYI 211 Query: 464 VICG 453 ++CG Sbjct: 212 LLCG 215
>KCC1G_RAT (Q7TNJ7) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 43.1 bits (100), Expect = 7e-04 Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 1/64 (1%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVME 465 +++ ++DFGL K+ + + V++ GTPGY+APE L + KA D +S GV+ Sbjct: 155 EENSKIMITDFGLSKM---EQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYI 211 Query: 464 VICG 453 ++CG Sbjct: 212 LLCG 215
>TLK2_MOUSE (O55047) Serine/threonine-protein kinase tousled-like 2 (EC| 2.7.11.1) (Tousled-like kinase 2) Length = 718 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMR------GTPGYLAPEWLT-----SQITEKADVYSFGV 477 K++DFGL K++D D V M GT YL PE +I+ K DV+S GV Sbjct: 556 KITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGV 615 Query: 476 VVMEVICGRKNLDTSLSEESI 414 + + + GRK + S++ I Sbjct: 616 IFYQCLYGRKPFGHNQSQQDI 636
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 42.7 bits (99), Expect = 0.001 Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 5/70 (7%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKM--RGTPGYLAPEWLTSQ---ITEKADVYSFG 480 LD + N KL+DFGL R + M RG+P Y+APE L S+ ++ D++S G Sbjct: 150 LDKNGNLKLADFGLASQFRRKDGTLRVSMDQRGSPPYMAPEVLYSEEGYYADRTDIWSIG 209 Query: 479 VVVMEVICGR 450 +++ ++ G+ Sbjct: 210 ILLFVLLTGQ 219
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 42.7 bits (99), Expect = 0.001 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 8/72 (11%) Frame = -2 Query: 644 LDDDFNAKLSDFGL-CKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE-------KADVY 489 LDD+ +LSDFG C L + + + ++ GTPGYLAPE L + E + D++ Sbjct: 161 LDDNMQIRLSDFGFSCHL---EAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLW 217 Query: 488 SFGVVVMEVICG 453 + GV++ ++ G Sbjct: 218 ACGVILFTLLAG 229
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 42.7 bits (99), Expect = 0.001 Identities = 39/123 (31%), Positives = 57/123 (46%), Gaps = 14/123 (11%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMS----QVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVME 465 N ++ G KLID S + + + GTP Y++PE L S+ +A D + GV++ E Sbjct: 137 NILITSTGHIKLIDFGFSVYESENIYMISGTPEYMSPEKLRSEDDGRASDYWGLGVMIYE 196 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVD---------LIDKNSNDMLAHKQDVI 312 ++CG S ++ H I LE V H V L+DKN L K + Sbjct: 197 MLCGDPPFYDSSADAIYHKI--LESNVVFPHYVSPVARCLITGLLDKNRATRLGTK-GIC 253 Query: 311 EIM 303 EIM Sbjct: 254 EIM 256
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 42.7 bits (99), Expect = 0.001 Identities = 22/65 (33%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI-TEKADVYSFGVVVMEV 462 + N KLSD+G+ + + + + GTPGY APE + EK D++S+G+V+ E+ Sbjct: 1424 EHINIKLSDYGISR---QSFHEGALGVEGTPGYQAPEIRPRIVYDEKVDMFSYGMVLYEL 1480 Query: 461 ICGRK 447 + G++ Sbjct: 1481 LSGQR 1485
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 42.7 bits (99), Expect = 0.001 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 8/137 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVV---TKMRGTPGYLAPEWLTSQIT---EKADVYSF 483 LD++ + K+SDFGL K +++ + + +RGT Y+ PE + DVYSF Sbjct: 165 LDNNMHVKISDFGLSKWMEQSTQKQYIERSALRGTLSYIPPEMFLENNKAPGPEYDVYSF 224 Query: 482 GVVVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAH--LVDLIDKNSNDMLAHKQDVIE 309 +V+ E++ +K ++++T++ L D+ D+ ++V + Sbjct: 225 AIVIWEILTQKK------PYAGLNMMTIIIRVAAGMRPSLQDVSDE-------WPEEVHQ 271 Query: 308 IMKLAMWCLQIDCKRRP 258 ++ L C D K+RP Sbjct: 272 MVNLMKRCWDQDPKKRP 288
>PHKG1_HUMAN (Q16816) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 386 Score = 42.7 bits (99), Expect = 0.001 Identities = 25/72 (34%), Positives = 42/72 (58%), Gaps = 8/72 (11%) Frame = -2 Query: 644 LDDDFNAKLSDFGL-CKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE-------KADVY 489 LDD+ N KL+DFG C+L + + + ++ GTP YLAPE + + E + D++ Sbjct: 157 LDDNMNIKLTDFGFSCQL---EPGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMW 213 Query: 488 SFGVVVMEVICG 453 S GV++ ++ G Sbjct: 214 STGVIMYTLLAG 225
>KCC1G_HUMAN (Q96NX5) Calcium/calmodulin-dependent protein kinase type 1G (EC| 2.7.11.17) (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 42.7 bits (99), Expect = 0.001 Identities = 22/64 (34%), Positives = 39/64 (60%), Gaps = 1/64 (1%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVME 465 +++ ++DFGL K+ + + +++ GTPGY+APE L + KA D +S GV+ Sbjct: 155 EENSKIMITDFGLSKM---EQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYI 211 Query: 464 VICG 453 ++CG Sbjct: 212 LLCG 215
>TLK1_MOUSE (Q8C0V0) Serine/threonine-protein kinase tousled-like 1 (EC| 2.7.11.1) (Tousled-like kinase 1) Length = 766 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 10/80 (12%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQV-----VTKMRGTPGYLAPEWLT-----SQITEKADVYSFGVV 474 K++DFGL K++D D V ++ GT YL PE +I+ K DV+S GV+ Sbjct: 604 KITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVI 663 Query: 473 VMEVICGRKNLDTSLSEESI 414 + + GRK + S++ I Sbjct: 664 FFQCLYGRKPFGHNQSQQDI 683
>TLK1_HUMAN (Q9UKI8) Serine/threonine-protein kinase tousled-like 1 (EC| 2.7.11.1) (Tousled-like kinase 1) (PKU-beta) Length = 766 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 10/80 (12%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQV-----VTKMRGTPGYLAPEWLT-----SQITEKADVYSFGVV 474 K++DFGL K++D D V ++ GT YL PE +I+ K DV+S GV+ Sbjct: 604 KITDFGLSKIMDDDSYGVDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVI 663 Query: 473 VMEVICGRKNLDTSLSEESI 414 + + GRK + S++ I Sbjct: 664 FFQCLYGRKPFGHNQSQQDI 683
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 42.4 bits (98), Expect = 0.001 Identities = 36/131 (27%), Positives = 62/131 (47%), Gaps = 2/131 (1%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ--ITEKADVYSFGVVVMEVICGR 450 K+ DFGL + D + + G+ + APE L +Q + D++SFG+V+ ++CG+ Sbjct: 263 KIIDFGLSNIFD--YRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGK 320 Query: 449 KNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWCLQIDC 270 D S ++L EK+K K D +H IE++ L + +D Sbjct: 321 VPFDDENS-------SILHEKIK---------KGKVDYPSHLS--IEVISLLTRMIVVDP 362 Query: 269 KRRPKMSDVVK 237 RR + +VV+ Sbjct: 363 LRRATLKNVVE 373
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVM 468 +D + + KL+D+G+CK +D + + GTP Y+APE L + D ++ GV++ Sbjct: 385 IDAEGHIKLTDYGMCKENIKD-GDLTSTFCGTPNYIAPEILRGDEYGFSVDWWALGVLMF 443 Query: 467 EVICGRKNLD 438 E++ GR D Sbjct: 444 EMMAGRSPFD 453
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 +D + + K++DFG+CK + GTP Y+APE + Q KA D ++FGV++ Sbjct: 457 VDAEGHIKIADFGMCK-EHMNEGDTTRTFCGTPDYIAPEIVAYQPYGKAVDWWAFGVLLY 515 Query: 467 EVICGRKNLDTSLSEE 420 E++ G+ D +E Sbjct: 516 EMLAGQPPFDGEDEDE 531
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/63 (34%), Positives = 37/63 (58%) Frame = -2 Query: 641 DDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEV 462 DD+F+ K DFGL QV ++ G+P Y+APE L + +AD+++ GV++ + Sbjct: 209 DDEFSVKAIDFGLSVFFRP--GQVFREVVGSPYYIAPEVLEKRYGPEADIWTAGVILYVL 266 Query: 461 ICG 453 + G Sbjct: 267 LTG 269
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 42.4 bits (98), Expect = 0.001 Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 16/170 (9%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVM 468 LD + K++DFGLCK + GTP +LAPE LT + T D + GV++ Sbjct: 790 LDTEGFVKIADFGLCK-EGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIY 848 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVD---------LIDKNSNDML-AHKQD 318 E++ G EE +++ ++V+ + L+ +N L A ++D Sbjct: 849 EMLVGESPFPGDDEEEVFD--SIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKD 906 Query: 317 VIEIMK-----LAMWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVA 183 ++ K L W +D K +P ++ E SN D F + Sbjct: 907 AEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDV----SNFDDEFTS 952
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 42.4 bits (98), Expect = 0.001 Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 16/170 (9%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLT-SQITEKADVYSFGVVVM 468 LD + K++DFGLCK + GTP +LAPE LT + T D + GV++ Sbjct: 789 LDTEGFVKIADFGLCK-EGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIY 847 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVD---------LIDKNSNDML-AHKQD 318 E++ G EE +++ ++V+ + L+ +N L A ++D Sbjct: 848 EMLVGESPFPGDDEEEVFD--SIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKD 905 Query: 317 VIEIMK-----LAMWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVA 183 ++ K L W +D K +P ++ E SN D F + Sbjct: 906 AEDVKKHPFFRLTDWSALMDKKVKPPFVPTIRGREDV----SNFDDEFTS 951
>PAK4_HUMAN (O96013) Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1)| (p21-activated kinase 4) (PAK-4) Length = 591 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 7/122 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 L D KLSDFG C + +++ + + GTP ++APE ++ + D++S G++V+ Sbjct: 448 LTHDGRVKLSDFGFCAQVSKEVPR-RKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVI 506 Query: 467 EVICGRKNLDTSLSEESIHLI-TLLEEKVKNAHLVDLIDKNSNDML-----AHKQDVIEI 306 E++ G +++ +I L ++KN H V K D L A + E+ Sbjct: 507 EMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAEL 566 Query: 305 MK 300 +K Sbjct: 567 LK 568
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 147 LDAHMNAKIADFGLSNMMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVIL 204 Query: 470 MEVICGRKNLD 438 ++CG D Sbjct: 205 YALLCGTLPFD 215
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 147 LDAHMNAKIADFGLSNMMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVIL 204 Query: 470 MEVICGRKNLD 438 ++CG D Sbjct: 205 YALLCGTLPFD 215
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 5/140 (3%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMR---GTPGYLAPEWLTS--QITEKADVYSFG 480 LD DFN KLSDFG K RD S + + G+ Y APE + D++S G Sbjct: 144 LDKDFNIKLSDFGFSKGCLRDGSGRIVLSKTFCGSAAYAAPEVRQGIPYQPKVYDIWSLG 203 Query: 479 VVVMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMK 300 V++ ++CG D S + + +++ H VD S ++ +D+I + Sbjct: 204 VILYIMVCGSMPYDDS---------DIKKLRIQKEHRVDF--PRSKNLTGECKDLIYRI- 251 Query: 299 LAMWCLQIDCKRRPKMSDVV 240 LQ D RR + +++ Sbjct: 252 -----LQPDVNRRLHIDEIL 266
>PMYT1_MOUSE (Q9ESG9) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 490 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/56 (39%), Positives = 30/56 (53%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVIC 456 KL DFGL L++ + G P Y+APE L ADV+S G+ ++EV C Sbjct: 239 KLGDFGL--LVELGSTGAGEAQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVAC 292
>PAK7_HUMAN (Q9P286) Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1)| (p21-activated kinase 7) (PAK-7) (PAK-5) Length = 719 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 2/106 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 L D KLSDFG C + +++ + + GTP ++APE ++ + D++S G++V+ Sbjct: 576 LTSDGRIKLSDFGFCAQVSKEVPK-RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVI 634 Query: 467 EVICGRKNLDTSLSEESIHLI-TLLEEKVKNAHLVDLIDKNSNDML 333 E+I G +++ I L +VK+ H V + + D++ Sbjct: 635 EMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLM 680
>RIPK5_MOUSE (Q6XUX1) Receptor-interacting serine/threonine-protein kinase 5 (EC| 2.7.11.1) (Dusty protein kinase) (Dusty PK) Length = 927 Score = 42.4 bits (98), Expect = 0.001 Identities = 38/143 (26%), Positives = 57/143 (39%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVME 465 LD AK++D G CK +V GTP ++APE T + DVY+FG++ Sbjct: 783 LDKQNRAKITDLGFCKPEAMMSGSIV----GTPIHMAPELFTGKYDNSVDVYAFGILFWY 838 Query: 464 VICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLAMWC 285 + G SI L E HL + + + + D E +L C Sbjct: 839 ICSG-----------SIKLPEAFERCASKDHLWNNVRRGTRPERLPVFDE-ECWQLMEAC 886 Query: 284 LQIDCKRRPKMSDVVKVLEGTMN 216 D +RP + V +L M+ Sbjct: 887 WDGDPLKRPLLGIVQPMLRSIMD 909
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 42.4 bits (98), Expect = 0.001 Identities = 37/162 (22%), Positives = 75/162 (46%), Gaps = 3/162 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPG--YLAPEWLT-SQITEKADVYSFGVV 474 ++ + K+SDFGL ++++ D T G + APE + + T +DV+S+G+V Sbjct: 810 INSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIV 869 Query: 473 VMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 + EV+ + ++ + + I +EE + +D + +L Sbjct: 870 MWEVVSYGERPYWEMTNQDV--IKAVEEGYRLPSPMDC--------------PAALYQLM 913 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMNAESNIDHNFVATNQVN 168 + C Q D RPK D+V +L+ + S++ A+++V+ Sbjct: 914 LDCWQKDRNSRPKFDDIVNMLDKLIRNPSSLKTLVNASSRVS 955
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 149 LDAHMNAKIADFGLSNMMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVIL 206 Query: 470 MEVICGRKNLD 438 ++CG D Sbjct: 207 YALLCGTLPFD 217
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 42.4 bits (98), Expect = 0.001 Identities = 22/71 (30%), Positives = 40/71 (56%), Gaps = 2/71 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LD NAK++DFGL ++ + + G+P Y APE ++ ++ + D++S GV++ Sbjct: 149 LDAHMNAKIADFGLSNMMSD--GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVIL 206 Query: 470 MEVICGRKNLD 438 ++CG D Sbjct: 207 YALLCGTLPFD 217
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 8/72 (11%) Frame = -2 Query: 644 LDDDFNAKLSDFGL-CKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE-------KADVY 489 LDD+ +LSDFG C L + + + ++ GTPGYLAPE L + E + D++ Sbjct: 161 LDDNMQIRLSDFGFSCHL---EPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLW 217 Query: 488 SFGVVVMEVICG 453 + GV++ ++ G Sbjct: 218 ACGVILFTLLAG 229
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 8/72 (11%) Frame = -2 Query: 644 LDDDFNAKLSDFGL-CKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE-------KADVY 489 LDD+ +LSDFG C L + + + ++ GTPGYLAPE L + E + D++ Sbjct: 161 LDDNMQIRLSDFGFSCHL---EPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLW 217 Query: 488 SFGVVVMEVICG 453 + GV++ ++ G Sbjct: 218 ACGVILFTLLAG 229
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVVM 468 + DD + KL+DFGL + + + GT YL+PE + ++DVYS GV+V Sbjct: 150 ISDDGDVKLADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVY 209 Query: 467 EVICG 453 E++ G Sbjct: 210 ELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVVM 468 + DD + KL+DFGL + + + GT YL+PE + ++DVYS GV+V Sbjct: 150 ISDDGDVKLADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVY 209 Query: 467 EVICG 453 E++ G Sbjct: 210 ELLTG 214
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWL-TSQITEKADVYSFGVVVM 468 LD + + K++DFG K + V + GTP Y+APE + T + D +SFGV++ Sbjct: 219 LDKNGHIKITDFGFAKYVP----DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIY 274 Query: 467 EVICG 453 E++ G Sbjct: 275 EMLAG 279
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 39.7 bits (91), Expect(2) = 0.001 Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI-TEKADVYSFGVVVM 468 +DD K++DFGL +L+ D+ + + + APE ++ ++K+DV+SFGV++ Sbjct: 358 VDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLH 417 Query: 467 EV 462 EV Sbjct: 418 EV 419 Score = 21.6 bits (44), Expect(2) = 0.001 Identities = 10/29 (34%), Positives = 16/29 (55%) Frame = -3 Query: 484 LVLWSWKSSVEERTSTLLYQKRASILLPC 398 L+L W+SS EER S +++ + C Sbjct: 458 LMLECWRSSPEERPSFATLREKLHAIHRC 486
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 42.0 bits (97), Expect = 0.002 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 2/71 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE--KADVYSFGVVV 471 LD N K++DFGL ++ RD + T G+P Y APE ++ ++ + DV+S GV++ Sbjct: 173 LDSKCNVKIADFGLSNIM-RDGHFLKTSC-GSPNYAAPEVISGKLYAGPEVDVWSCGVIL 230 Query: 470 MEVICGRKNLD 438 ++CG D Sbjct: 231 YALLCGTLPFD 241
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 42.0 bits (97), Expect = 0.002 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Frame = -2 Query: 638 DDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVMEV 462 DD K++DFG+ K + K+ G+ YL+PE + + D+YSFG+V+ E+ Sbjct: 143 DDDIIKVTDFGIAKASNESTITTTNKVVGSAHYLSPEQAQGIPVDCRTDIYSFGIVLYEM 202 Query: 461 ICGRKNLD 438 G+ D Sbjct: 203 ATGKVPYD 210
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 42.0 bits (97), Expect = 0.002 Identities = 27/65 (41%), Positives = 37/65 (56%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTS-QITEKADVYSFGVVVM 468 LD + L DFGLCKL +D + T GTP YLAPE L T+ D ++ GV++ Sbjct: 478 LDYQGHIALCDFGLCKLNMKDDDKTDT-FCGTPEYLAPELLLGLGYTKAVDWWTLGVLLY 536 Query: 467 EVICG 453 E++ G Sbjct: 537 EMLTG 541
>PHKG1_RAT (P13286) Phosphorylase b kinase gamma catalytic chain, skeletal| muscle isoform (EC 2.7.11.19) (Phosphorylase kinase gamma subunit 1) Length = 387 Score = 42.0 bits (97), Expect = 0.002 Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 8/72 (11%) Frame = -2 Query: 644 LDDDFNAKLSDFGL-CKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITE-------KADVY 489 LDD+ N KL+DFG C+L + + ++ GTP YLAPE + + E + D++ Sbjct: 157 LDDNMNIKLTDFGFSCQL---QPGEKLREVCGTPSYLAPEIIQCSMDEGHPGYGKEVDMW 213 Query: 488 SFGVVVMEVICG 453 S GV++ ++ G Sbjct: 214 STGVIMYTLLAG 225
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 42.0 bits (97), Expect = 0.002 Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 6/146 (4%) Frame = -2 Query: 635 DFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ------ITEKADVYSFGVV 474 DF K+ DFG+ RD+ + +G G L W+ + T +D++SFGVV Sbjct: 1170 DFTVKIGDFGMT----RDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVV 1225 Query: 473 VMEVICGRKNLDTSLSEESIHLITLLEEKVKNAHLVDLIDKNSNDMLAHKQDVIEIMKLA 294 + E+ TSL+E+ ++ E+ +K +D+ N + V ++M++ Sbjct: 1226 LWEI--------TSLAEQPYQGLS-NEQVLKFVMDGGYLDQPDN----CPERVTDLMRM- 1271 Query: 293 MWCLQIDCKRRPKMSDVVKVLEGTMN 216 C Q + K RP ++V +L+ ++ Sbjct: 1272 --CWQFNPKMRPTFLEIVNLLKDDLH 1295
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 42.0 bits (97), Expect = 0.002 Identities = 22/56 (39%), Positives = 38/56 (67%), Gaps = 1/56 (1%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEW-LTSQITEKADVYSFGVVVMEVI 459 K++DFGL ++ID ++ + T + + APE + ++ T K+DV+SFGVV+ E+I Sbjct: 374 KVADFGLARVIDEEIYEAHTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEII 429
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 42.0 bits (97), Expect = 0.002 Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 2/71 (2%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQI--TEKADVYSFGVVV 471 LDD+ N K++DFGL ++ D + + T G+P Y APE + ++ + DV+S G+V+ Sbjct: 164 LDDNLNVKIADFGLSNIM-TDGNFLKTSC-GSPNYAAPEVINGKLYAGPEVDVWSCGIVL 221 Query: 470 MEVICGRKNLD 438 ++ GR D Sbjct: 222 YVMLVGRLPFD 232
>PMYT1_HUMAN (Q99640) Membrane-associated tyrosine- and threonine-specific| cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) Length = 499 Score = 42.0 bits (97), Expect = 0.002 Identities = 22/56 (39%), Positives = 30/56 (53%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKADVYSFGVVVMEVIC 456 KL DFGL L++ + G P Y+APE L ADV+S G+ ++EV C Sbjct: 248 KLGDFGL--LVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVAC 301
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 + ++ K+ DFGL ++ + T + GTP Y+APE L Q +ADV+S G V+ Sbjct: 193 ITENMELKVGDFGLAARLEPPEQRKKT-ICGTPNYVAPEVLLRQGHGPEADVWSLGCVMY 251 Query: 467 EVICGRKNLDTSLSEESIHLI 405 ++CG +T+ +E+ I Sbjct: 252 TLLCGSPPFETADLKETYRCI 272
>ATG1_KLULA (Q6CSX2) Serine/threonine-protein kinase ATG1 (EC 2.7.11.1)| (Autophagy-related protein 1) Length = 831 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Frame = -2 Query: 623 KLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICGRK 447 K++DFG + + + + + G+P Y+APE L Q KAD++S G V+ E+ CGR Sbjct: 204 KIADFGFARFLPN--TSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGRP 261 Query: 446 NLDTSLSEESIHLITLLEEKVKNAH 372 S E L +K+K A+ Sbjct: 262 PFKASNHLE-------LFQKIKKAN 279
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 1/65 (1%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEKA-DVYSFGVVVM 468 LD + + K++DFG K ++ V + GTP Y+APE +T++ K+ D +S GV++ Sbjct: 201 LDRNGHIKITDFGFAK----EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIY 256 Query: 467 EVICG 453 E++ G Sbjct: 257 EMLAG 261
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 42.0 bits (97), Expect = 0.002 Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 8/121 (6%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVM 468 LD + L+DFGLCK +S T GTP YLAPE + Q D + G V+ Sbjct: 294 LDSMGHVVLTDFGLCKE-GIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLY 352 Query: 467 EVICGRKNL----DTSLSEESIHLITLLEEKVKN---AHLVDLIDKNSNDMLAHKQDVIE 309 E++ G + + +H L V + L +L++KN + L K+D +E Sbjct: 353 EMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWSILEELLEKNRQNRLGAKEDFLE 412 Query: 308 I 306 I Sbjct: 413 I 413
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 42.0 bits (97), Expect = 0.002 Identities = 37/120 (30%), Positives = 58/120 (48%), Gaps = 7/120 (5%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQITEK-ADVYSFGVVVM 468 LD + L+DFGLCK + + + + GTP YLAPE L Q ++ D + G V+ Sbjct: 230 LDSQGHIVLTDFGLCKE-NIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLY 288 Query: 467 EVICGRKNLDTSLSEESIHLITLLEEKVKN-----AHLVD-LIDKNSNDMLAHKQDVIEI 306 E++ G + + E I ++KN HL++ L+ K+ L K D +EI Sbjct: 289 EMLYGLPPFYSRNTAEMYDNILNKPLQLKNITNSARHLLEGLLQKDRTKRLGAKDDFMEI 348
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/60 (38%), Positives = 38/60 (63%), Gaps = 1/60 (1%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ G Sbjct: 381 SVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 439
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/60 (38%), Positives = 38/60 (63%), Gaps = 1/60 (1%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ G Sbjct: 381 SVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 439
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/60 (38%), Positives = 38/60 (63%), Gaps = 1/60 (1%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ G Sbjct: 381 SVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 439
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/60 (38%), Positives = 38/60 (63%), Gaps = 1/60 (1%) Frame = -2 Query: 629 NAKLSDFGLCKLIDRDMSQVVTKMRGTPGYLAPEWLTSQ-ITEKADVYSFGVVVMEVICG 453 + KL+DFG C I + S+ T M GTP ++APE +T + K D++S G++ +E++ G Sbjct: 381 SVKLTDFGFCAQITPEQSKRST-MVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEG 439
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 3/67 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLI-DRDMSQVVTKMRGTPGYLAPEWLTSQ--ITEKADVYSFGVV 474 LD+ N K+SDFGL + + +++ KM GT Y+APE L + E DV+S G+V Sbjct: 138 LDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSCGIV 197 Query: 473 VMEVICG 453 + ++ G Sbjct: 198 LTAMLAG 204
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 41.6 bits (96), Expect = 0.002 Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 3/67 (4%) Frame = -2 Query: 644 LDDDFNAKLSDFGLCKLI-DRDMSQVVTKMRGTPGYLAPEWLTSQ--ITEKADVYSFGVV 474 LD+ N K+SDFGL + + +++ KM GT Y+APE L + E DV+S G+V Sbjct: 138 LDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLKRKEFHAEPVDVWSCGIV 197 Query: 473 VMEVICG 453 + ++ G Sbjct: 198 LTAMLAG 204 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,853,639 Number of Sequences: 219361 Number of extensions: 1877520 Number of successful extensions: 6493 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5882 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6110 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6029593548 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
