ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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更新日：2016年5月1日

Clone Information

BLAST Search Result

Clone Name rbaal29n11
Clone Library Name barley_pub
No. Definition Score
(bits)		 E
Value
1IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast... 313 3e-85
2IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 312 8e-85
3IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 303 3e-82
4IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 302 6e-82
5IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (E... 256 5e-68
6IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic ... 256 5e-68
7IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic ... 256 5e-68
8IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic ... 252 7e-67
9IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic ... 249 5e-66
10IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondri... 247 3e-65
11IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial... 246 5e-65
12IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondri... 246 7e-65
13IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 234 3e-61
14IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 234 3e-61
15IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondri... 230 3e-60
16IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic ... 225 1e-58
17IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondri... 223 6e-58
18IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal ... 220 4e-57
19IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 220 4e-57
20IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mi... 219 9e-57
21IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42... 215 1e-55
22IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondri... 209 5e-54
23IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondri... 202 1e-51
24LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 44 7e-04
25LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 44 7e-04
26LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 44 7e-04
27LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 42 0.001
28LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 42 0.003
29LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 41 0.004
30IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,... 40 0.006
31IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alph... 40 0.006
32LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 40 0.006
33LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 40 0.006
34LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 40 0.007
35LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 40 0.010
36IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alph... 40 0.010
37LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 39 0.016
38LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 39 0.016
39LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 39 0.016
40LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 39 0.016
41IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] sub... 39 0.021
42LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.028
43LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.028
44LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.037
45LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 38 0.037
46LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.048
47LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.048
48LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.048
49LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.048
50LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.048
51LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.048
52LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.062
53LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.062
54LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.062
55LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.062
56LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.082
57LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.082
58LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 37 0.082
59LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
60LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
61LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
62LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
63LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
64LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
65LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
66LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
67LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
68LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
69LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
70LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.11
71LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.14
72LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.14
73LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.14
74LEU3_SYMTH (Q67JY2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.14
75LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.14
76LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 36 0.14
77LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.18
78LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.18
79LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
80LEU3_BACHK (Q6HLF2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
81LEU3_BACAN (Q81T67) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
82LEU3_BUCTS (O31292) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
83LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
84LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
85LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
86LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.24
87LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.31
88LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.31
89LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.31
90LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.31
91LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.31
92LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 35 0.31
93LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast... 34 0.40
94LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.40
95LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.40
96LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.40
97LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.40
98LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.40
99LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.53
100LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.53
101LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.53
102LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.53
103LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.53
104LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.53
105LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 34 0.53
106LEU3_STRT2 (Q5M405) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.69
107LEU3_STRT1 (Q5LZF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.69
108LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.69
109LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.69
110LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.69
111LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 0.90
112LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 1.2
113LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 1.2
114LEU3_BACC1 (Q73B99) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 1.2
115LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 1.2
116LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 33 1.2
117LEU3_LACLA (Q02143) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.5
118LEU3_BUCUN (Q9EVI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.5
119LEU3_BUCBP (P59515) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.5
120LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.5
121LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 1.5
122LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
123LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
124LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
125LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
126IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)... 32 2.0
127LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.0
128ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1) 32 2.0
129LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.6
130LEU31_DECAR (Q47HR1) 3-isopropylmalate dehydrogenase 1 (EC 1.1.1... 32 2.6
131LEU3_CEPAC (Q12545) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 32 2.6
132OM25_BRUCA (Q45110) 25 kDa outer-membrane immunogenic protein pr... 31 3.4
133LEU3_STAS1 (Q49Z13) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.4
134LEU3_BURCE (Q845W3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.4
135LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 3.4
136LEU3_STRR6 (Q8DPJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
137LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
138LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
139LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
140LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
141LEU3_BURPS (Q63JL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
142LEU3_BURMA (Q62AI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
143LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
144LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 31 4.5
145LEU3_BUCUL (Q9AQC8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.8
146LEU3_PROMP (Q7V1R9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.8
147INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin bet... 30 5.8
148OM25_BRUSU (Q45689) 25 kDa outer-membrane immunogenic protein pr... 30 5.8
149OM25_BRUAB (Q44664) 25 kDa outer-membrane immunogenic protein pr... 30 5.8
150LEU3_NEILA (P50180) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 5.8
151LEU3_BACCA (P05644) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.6
152LEU3_BLOFL (Q7VQJ7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.6
153Y1185_METJA (Q58585) Hypothetical protein MJ1185 30 7.6
154LEU3_PICST (O94114) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.6
155LEU3_THETN (Q8RDK0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 7.6
156LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 10.0
157OM25_BRUME (Q45321) 25 kDa outer-membrane immunogenic protein pr... 30 10.0
158LYS12_YEAST (P40495) Homoisocitrate dehydrogenase, mitochondrial... 30 10.0
159LEU3_LISMO (Q8Y5R8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 10.0
160LEU3_LISMF (Q71Y34) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 10.0
161LEU3_AZOVI (P96197) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 10.0
162SYNJ1_BOVIN (O18964) Synaptojanin-1 (EC 3.1.3.36) (Synaptic inos... 30 10.0
163LEU3_BUCAI (P56933) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 10.0
164LEU3_STAAR (Q6GF15) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 10.0
165LEU3_BUCML (Q9EVG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85... 30 10.0 
>IDHP_MEDSA (Q40345) Isocitrate dehydrogenase [NADP], chloroplast precursor (EC|
           1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (Fragment)
          Length = 433

 Score =  313 bits (803), Expect = 3e-85
 Identities = 153/168 (91%), Positives = 161/168 (95%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+
Sbjct: 260 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLV 319

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA LL+F 
Sbjct: 320 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNATLLDFT 379

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224
           +KLE AC+G VESGKMTKDLAL++HG SK++R  YLNTEEFIDAVAAE
Sbjct: 380 EKLEAACIGVVESGKMTKDLALILHG-SKLSREHYLNTEEFIDAVAAE 426
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>IDHC_SOYBN (Q06197) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 413

 Score =  312 bits (799), Expect = 8e-85
 Identities = 151/168 (89%), Positives = 162/168 (96%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           SK+EAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+
Sbjct: 240 SKFEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLV 299

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA+LL+F 
Sbjct: 300 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFT 359

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224
           +KLE AC+G VE+GKMTKDLAL++HG SK++R  YLNTEEFIDAVAAE
Sbjct: 360 EKLEAACIGVVEAGKMTKDLALILHG-SKLSREHYLNTEEFIDAVAAE 406
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>IDHC_TOBAC (P50218) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 415

 Score =  303 bits (777), Expect = 3e-82
 Identities = 147/168 (87%), Positives = 157/168 (93%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           SKYE AGIWYEHRLIDDM AYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+
Sbjct: 239 SKYEEAGIWYEHRLIDDMAAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLV 298

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKTIEAEAAHGTVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRA LD+N RLL+F 
Sbjct: 299 CPDGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFT 358

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224
           +KLE AC+G VESGKMTKDLAL++HG SK++R  YLNTEEFIDAVA E
Sbjct: 359 EKLEAACIGAVESGKMTKDLALIIHG-SKLSRDHYLNTEEFIDAVADE 405
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>IDHC_SOLTU (P50217) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 416

 Score =  302 bits (774), Expect = 6e-82
 Identities = 146/168 (86%), Positives = 156/168 (92%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           SKYE AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVL+
Sbjct: 239 SKYEEAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLV 298

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKTIEAEAAHGTVTRH+RVHQKGGETSTNSIASIFAWTRGLAHRA LD+N RLL+F 
Sbjct: 299 CPDGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFT 358

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224
           +KLE AC+G VESGKMTKDLAL++   SK++R  YLNTEEFIDAVA E
Sbjct: 359 EKLEAACIGAVESGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADE 406
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>IDHC_RAT (P41562) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  256 bits (654), Expect = 5e-68
 Identities = 121/163 (74%), Positives = 140/163 (85%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           SK+EA  IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+
Sbjct: 237 SKFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLI 296

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKT+EAEAAHGTVTRH+R++QKG ETSTN IASIFAW+RGLAHRAKLD+N  L  FA
Sbjct: 297 CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFA 356

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239
             LEE C+ T+E+G MTKDLA  + G   V RSDYLNT EF+D
Sbjct: 357 NALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
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>IDHC_MICOH (Q9Z2K8) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  256 bits (654), Expect = 5e-68
 Identities = 120/163 (73%), Positives = 141/163 (86%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           S++EA  IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+
Sbjct: 237 SQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLI 296

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKT+EAEAAHGTVTRH+R+HQKG ETSTN IASIFAW+RGLAHRA+LD+N  L  FA
Sbjct: 297 CPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFA 356

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239
           + LEE C+ T+E+G MTKDLA  + G   V RSDYLNT EF+D
Sbjct: 357 KALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
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>IDHC_MICME (Q9Z2K9) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  256 bits (654), Expect = 5e-68
 Identities = 120/163 (73%), Positives = 141/163 (86%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           S++EA  IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+
Sbjct: 237 SQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLI 296

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKT+EAEAAHGTVTRH+R+HQKG ETSTN IASIFAW+RGLAHRA+LD+N  L  FA
Sbjct: 297 CPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFA 356

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239
           + LEE C+ T+E+G MTKDLA  + G   V RSDYLNT EF+D
Sbjct: 357 KALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
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>IDHC_HUMAN (O75874) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  252 bits (644), Expect = 7e-67
 Identities = 120/163 (73%), Positives = 139/163 (85%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           S++EA  IWYEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+
Sbjct: 237 SQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLV 296

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKT+EAEAAHGTVTRH+R++QKG ETSTN IASIFAWTRGLAHRAKLD+N  L  FA
Sbjct: 297 CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239
             LEE  + T+E+G MTKDLA  + G   V RSDYLNT EF+D
Sbjct: 357 NALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
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>IDHC_MOUSE (O88844) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 414

 Score =  249 bits (637), Expect = 5e-66
 Identities = 118/163 (72%), Positives = 140/163 (85%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           S++EA  I YEHRLIDDMVA A+KSEGG++WACKNYDGDVQSD +AQG+GSLG+MTSVL+
Sbjct: 237 SQFEAQNICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLI 296

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKT+EAEAAHGTVTRH+R++QKG ETSTN IASIFAW+RGLAHRAKLD+N  L  FA
Sbjct: 297 CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFA 356

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFID 239
           + LE+ C+ T+E+G MTKDLA  + G   V RSDYLNT EF+D
Sbjct: 357 KALEDVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMD 399
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>IDHP_BOVIN (Q04467) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  247 bits (630), Expect = 3e-65
 Identities = 120/166 (72%), Positives = 136/166 (81%), Gaps = 1/166 (0%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           ++++   IWYEHRLIDDMVA  LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVL+
Sbjct: 276 TEFDKHKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLV 335

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           CPDGKTIEAEAAHGTVTRH+R HQKG  TSTN IASIFAWTRGL HR KLD N  L+ FA
Sbjct: 336 CPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233
           Q LE+ CV TVESG MTKDLA  +HG S V  ++ +LNT +F+D +
Sbjct: 396 QTLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTI 441
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>IDHP_PIG (P33198) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M) (Fragment)
          Length = 421

 Score =  246 bits (628), Expect = 5e-65
 Identities = 120/159 (75%), Positives = 132/159 (83%), Gaps = 1/159 (0%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI 527
           IWYEHRLIDDMVA  LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTI
Sbjct: 252 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 311

Query: 526 EAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEAC 347
           EAEAAHGTVTRH+R HQKG  TSTN IASIFAWTRGL HR KLD N  L+ FAQ LE+ C
Sbjct: 312 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVC 371

Query: 346 VGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233
           V TVESG MTKDLA  +HG S V  ++ +LNT +F+D +
Sbjct: 372 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTI 410
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>IDHP_HUMAN (P48735) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 452

 Score =  246 bits (627), Expect = 7e-65
 Identities = 120/159 (75%), Positives = 132/159 (83%), Gaps = 1/159 (0%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI 527
           IWYEHRLIDDMVA  LKS GG+VWACKNYDGDVQSD LAQGFGSLGLMTSVL+CPDGKTI
Sbjct: 283 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342

Query: 526 EAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEAC 347
           EAEAAHGTVTRH+R HQKG  TSTN IASIFAWTRGL HR KLD N  L+ FAQ LE+ C
Sbjct: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402

Query: 346 VGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233
           V TVESG MTKDLA  +HG S V  ++ +LNT +F+D +
Sbjct: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTI 441
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>IDH_MYCTU (P65097) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 409

 Score =  234 bits (596), Expect = 3e-61
 Identities = 115/166 (69%), Positives = 134/166 (80%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           +++EAAG+ YEHRLIDDMVA  LK EGGYVWACKNYDGDVQSD +AQG+GSLGLMTSVLM
Sbjct: 240 AQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLM 299

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
             DGKT+EAEAAHGTVTRH+R +Q G  TSTN IASIFAWTRGL HR KLD    +++FA
Sbjct: 300 TADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFA 359

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
            KLE   + TVESGKMTKDLA+L+         D+LN+EEF+DA+A
Sbjct: 360 HKLESVVIATVESGKMTKDLAILIG-----PEQDWLNSEEFLDAIA 400
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>IDH_MYCBO (P65098) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 409

 Score =  234 bits (596), Expect = 3e-61
 Identities = 115/166 (69%), Positives = 134/166 (80%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           +++EAAG+ YEHRLIDDMVA  LK EGGYVWACKNYDGDVQSD +AQG+GSLGLMTSVLM
Sbjct: 240 AQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLM 299

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
             DGKT+EAEAAHGTVTRH+R +Q G  TSTN IASIFAWTRGL HR KLD    +++FA
Sbjct: 300 TADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFA 359

Query: 367 QKLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
            KLE   + TVESGKMTKDLA+L+         D+LN+EEF+DA+A
Sbjct: 360 HKLESVVIATVESGKMTKDLAILIG-----PEQDWLNSEEFLDAIA 400
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>IDHP_MOUSE (P54071) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (ICD-M)
          Length = 523

 Score =  230 bits (587), Expect = 3e-60
 Identities = 115/159 (72%), Positives = 127/159 (79%), Gaps = 1/159 (0%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI 527
           IWYEHRLIDDMVA  LKS GG+VWACKNYDGDVQSD LA  FGSLGLMTSVL+CPDGKTI
Sbjct: 355 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILASRFGSLGLMTSVLVCPDGKTI 414

Query: 526 EAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEAC 347
           EAEAAHGTVTRH+R HQKG  TST  IASIFAWTRGL HR KLD N  L+ FAQ  E+ C
Sbjct: 415 EAEAAHGTVTRHYREHQKGRPTSTKGIASIFAWTRGLEHRGKLDGNQDLIRFAQTREKVC 474

Query: 346 VGTVESGKMTKDLALLVHGSSKVTRSD-YLNTEEFIDAV 233
           V TVE G MTKDLA  +HG S V  ++ +LNT +F+D +
Sbjct: 475 VQTVE-GAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTI 512
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>IDHC_YEAST (P41939) Isocitrate dehydrogenase [NADP] cytoplasmic (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 412

 Score =  225 bits (573), Expect = 1e-58
 Identities = 116/165 (70%), Positives = 133/165 (80%), Gaps = 1/165 (0%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545
           K+E+ GIWYEHRLIDDMVA  LKS+GGY+ A KNYDGDV+SD +AQGFGSLGLMTSVL+ 
Sbjct: 238 KFESLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLIT 297

Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365
           PDGKT E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTRG+  R KLD+   +++F Q
Sbjct: 298 PDGKTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQ 357

Query: 364 KLEEACVGTV-ESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
            LE A V TV E G MTKDLAL++    K  RS Y+ TEEFIDAV
Sbjct: 358 ILESATVNTVQEDGIMTKDLALIL---GKSERSAYVTTEEFIDAV 399
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>IDH1_CANTR (O13285) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP) (CtIDP1)
          Length = 430

 Score =  223 bits (567), Expect = 6e-58
 Identities = 113/167 (67%), Positives = 133/167 (79%), Gaps = 1/167 (0%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           +++E  G+WYEHRLIDDMVA  +KS+GG+V A KNYDGDVQSD +AQGFGSLGLMTS LM
Sbjct: 262 AEFEKQGLWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSALM 321

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
            PDGK  EAEAAHGTVTRH+R HQ+G ETSTNSIASIFAWTRGLA R KLD+   +++FA
Sbjct: 322 TPDGKAYEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGKLDETPDVVDFA 381

Query: 367 QKLEEACVGTVESGK-MTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
            KLE+A + TVE  + MTKDLAL +    K  RS Y+ T EF+DAVA
Sbjct: 382 SKLEQATIDTVEVDRIMTKDLALAM---GKTDRSAYVTTTEFLDAVA 425
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>IDH2_CANTR (O13294) Isocitrate dehydrogenase [NADP] peroxisomal (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (PS-NADP-IDH)
           (CtIDP2)
          Length = 410

 Score =  220 bits (560), Expect = 4e-57
 Identities = 112/167 (67%), Positives = 130/167 (77%), Gaps = 1/167 (0%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           +K +  GIWYEHRLIDDMVA  LKS+GGY+ A KNYDGDVQSD +AQGFGSLGLMTSVL+
Sbjct: 238 TKMDELGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLV 297

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
            PDGK  E+EAAHGTVTRH+R HQ+G ETSTNSIASI+AWTRGL  R KLDD   +++FA
Sbjct: 298 TPDGKAFESEAAHGTVTRHYRQHQQGKETSTNSIASIYAWTRGLIQRGKLDDTPEVVKFA 357

Query: 367 QKLEEACVGTVESGK-MTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++LE+A + TV     MTKDLAL      K  RS Y+ TEEFID VA
Sbjct: 358 EELEKAVIETVSKDNIMTKDLALT---QGKTDRSSYVTTEEFIDGVA 401
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>IDH_SPHYA (P50215) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 406

 Score =  220 bits (560), Expect = 4e-57
 Identities = 108/164 (65%), Positives = 130/164 (79%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545
           K++AAGI YEHRLIDDMVA ALK  G +VWACKNYDGDVQSD +AQGFGSLGLMTSVL+ 
Sbjct: 236 KFKAAGIVYEHRLIDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLS 295

Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365
           PDGKT+EAEAAHGTVTRH+R HQ+G  TSTN IASIFAWT+GL+ R K DD   +++FA+
Sbjct: 296 PDGKTVEAEAAHGTVTRHYRQHQQGKATSTNPIASIFAWTQGLSFRGKFDDTPDVVKFAE 355

Query: 364 KLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
            LE+ C+ TVE G MTKDLALL+          ++ TE+F +A+
Sbjct: 356 TLEQVCIKTVEGGAMTKDLALLIGPDQA-----WMTTEQFFEAI 394
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>IDHP_SCHPO (O14254) Probable isocitrate dehydrogenase [NADP], mitochondrial|
           precursor (EC 1.1.1.42) (Oxalosuccinate decarboxylase)
           (IDH) (NADP(+)-specific ICDH) (IDP)
          Length = 418

 Score =  219 bits (557), Expect = 9e-57
 Identities = 108/167 (64%), Positives = 131/167 (78%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545
           K+E  G+WY+HRLIDDMVA A+KS GG+VWACKNYDGDV SD +AQ +GSLGLMTSVL+ 
Sbjct: 248 KFEELGLWYQHRLIDDMVAQAIKSNGGFVWACKNYDGDVMSDVVAQAYGSLGLMTSVLIH 307

Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365
           P+G+T E+EAAHGTV RH+  + KG +TSTNSIASIFAWTRGLAHR +LD N RL++FA 
Sbjct: 308 PNGRTFESEAAHGTVQRHYMQYLKGKKTSTNSIASIFAWTRGLAHRGRLDGNERLVKFAN 367

Query: 364 KLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224
            LE ACV  VE G MTKDL LL       + + Y++T EF+DAV +E
Sbjct: 368 ALEHACVRCVEKGIMTKDLYLL-----SKSPNGYVDTFEFLDAVKSE 409
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>IDHH_YEAST (P53982) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 420

 Score =  215 bits (547), Expect = 1e-55
 Identities = 110/166 (66%), Positives = 131/166 (78%), Gaps = 1/166 (0%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545
           K++A  I YEHRLIDDMVA  LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ 
Sbjct: 238 KFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILIT 297

Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365
           PDGKT E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR +  R KLD+   +++F  
Sbjct: 298 PDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGN 357

Query: 364 KLEEACVGTVE-SGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
            LE+A + TV+  GKMTKDLAL++    K  RS Y+ TEEFID VA
Sbjct: 358 LLEKATLDTVQVGGKMTKDLALML---GKTNRSSYVTTEEFIDEVA 400
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>IDHP_YEAST (P21954) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP)
          Length = 428

 Score =  209 bits (533), Expect = 5e-54
 Identities = 109/166 (65%), Positives = 129/166 (77%), Gaps = 1/166 (0%)
 Frame = -2

Query: 727 SKYEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           SK+E  GI YEHRLIDDMVA  +KS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+
Sbjct: 254 SKFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILV 313

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
            PDGKT E+EAAHGTVTRH+R +QKG ETSTNSIASIFAW+RGL  R +LD+   L +FA
Sbjct: 314 TPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFA 373

Query: 367 QKLEEACVGTV-ESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
             LE A + TV + G MTKDLAL    +    RS Y+ TEEF+DAV
Sbjct: 374 NILESATLNTVQQDGIMTKDLALACGNNE---RSAYVTTEEFLDAV 416
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>IDHP_ASPNG (P79089) Isocitrate dehydrogenase [NADP], mitochondrial precursor|
           (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH)
           (NADP(+)-specific ICDH) (IDP)
          Length = 498

 Score =  202 bits (513), Expect = 1e-51
 Identities = 102/164 (62%), Positives = 123/164 (75%), Gaps = 1/164 (0%)
 Frame = -2

Query: 721 YEAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           +EA  +WYEHRLIDDMVA  +KSEGG+V A KNYDGDVQSD +AQGFGSLGLMTS L+ P
Sbjct: 326 FEAKNLWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSTLVTP 385

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
            G+  E+EAAHGTVTRH+R HQKG ETSTN IASIFAWTRGL  R KLD+   ++ FA++
Sbjct: 386 TGEAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEE 445

Query: 361 LEEACVGTV-ESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
           LE AC+  V + G MTKDLAL      +  R  ++ T E++ AV
Sbjct: 446 LERACIEVVNDEGIMTKDLAL---ACGRKEREAWVTTREYMAAV 486
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>LEU3_PELUB (Q4FP17) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 368

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 42/143 (29%), Positives = 60/143 (41%), Gaps = 1/143 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L D+     LK+   + V    N  GD+ SD  +   GSLGL+ S  +    K  E  
Sbjct: 225 HMLADNCAMQLLKNPKQFDVIVTDNLFGDMLSDQASMLTGSLGLLPSASLGAKNKDGEMR 284

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
           A +  +  H       G+   N IASI ++   L +   LD        A  LE+A    
Sbjct: 285 AMYEPI--HGSAPDIAGKEIANPIASILSFAMALRYSLDLDSE------ADALEKAVQDV 336

Query: 337 VESGKMTKDLALLVHGSSKVTRS 269
           +  G  TKD  +L  G  +V+ S
Sbjct: 337 LNDGLRTKD--ILSQGKKEVSTS 357
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>LEU3_CAMJR (Q5HS77) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 2/157 (1%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-E 524
           E+  +D+     +K+   + V  C N  GD+ SD LA   GSLGL++S  +   G  + E
Sbjct: 216 EYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYE 275

Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344
                     H  +         N IA I +    L +  K +      + AQ +E A  
Sbjct: 276 PAGGSAPDIAHLNI--------ANPIAQILSAALMLKYSFKEE------QAAQDIENAIS 321

Query: 343 GTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
             +  GKMTKDL              YLNT+E  D +
Sbjct: 322 LALAQGKMTKDL----------NAKSYLNTDEMGDCI 348
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>LEU3_CAMJE (Q9PLW0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 44/157 (28%), Positives = 64/157 (40%), Gaps = 2/157 (1%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTI-E 524
           E+  +D+     +K+   + V  C N  GD+ SD LA   GSLGL++S  +   G  + E
Sbjct: 216 EYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYE 275

Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344
                     H  +         N IA I +    L +  K +      + AQ +E A  
Sbjct: 276 PAGGSAPDIAHLNI--------ANPIAQILSAALMLKYSFKEE------QAAQDIENAIS 321

Query: 343 GTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
             +  GKMTKDL              YLNT+E  D +
Sbjct: 322 LALAQGKMTKDL----------NAKSYLNTDEMGDCI 348
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>LEU3_BACME (P41019) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 2/159 (1%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D      +++   + V   +N  GD+ SD  +   GSLG++ S  +  DG ++  
Sbjct: 215 EHMLVDSAAMQLIRNPKYFDVVVTENMFGDILSDEASMLTGSLGMLPSASLTADGPSL-Y 273

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSI-ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344
           E  HG+           G+   N I A+I +    L H   L+  A +      +E+A  
Sbjct: 274 EPVHGSAP------DIAGQNKANPIAAAILSAAMLLRHSFGLEKEAAV------IEQAVE 321

Query: 343 GTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
             + +G  T DLA           + YL T++ ++ + A
Sbjct: 322 SVLHAGHRTADLA---------DGNHYLGTDKMVEVITA 351
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>LEU3_AGRT5 (P24404) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           N  GD+ SD  A   GSLG++ S  L  PD KT + +A +  V  H       G++  N 
Sbjct: 246 NLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKAMYEPV--HGSAPDIAGKSIANP 303

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 269
           IA I ++   L +   + D       A KLE A    ++ G  T D  ++  G  +V   
Sbjct: 304 IAMIASFAMCLRYSFNMVDE------ATKLEAAIANVLDKGIRTAD--IMADGCRQV--- 352

Query: 268 DYLNTEEFIDAVAAE 224
               T +  DAV AE
Sbjct: 353 ---GTSDMGDAVLAE 364
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>LEU3_BACLD (Q65GI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D+     + + G + +   +N  GD+ SD  +   GSLG++ S  +   G  +  
Sbjct: 219 EHMLVDNAAMQLIYAPGQFDIIVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLY- 277

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N +A+I      L+    L  +  L   AQ +E A   
Sbjct: 278 EPVHGSAP------DIAGQNIANPLAAI------LSAAMMLRTSFGLEAEAQAVEHAVDQ 325

Query: 340 TVESGKMTKDLA 305
            + +GK TKDLA
Sbjct: 326 VLRAGKRTKDLA 337
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>IDH3A_RAT (Q99NA5) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTQSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 269
           A + +    L H         L + A K+E AC  T++ GK +TKDL     G+SK   S
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDLG----GNSKC--S 352

Query: 268 DYLNTEE 248
           D+  TEE
Sbjct: 353 DF--TEE 357
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>IDH3A_BOVIN (P41563) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH) (Isocitrate
           dehydrogenase subunits 3/4)
          Length = 366

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 42/127 (33%), Positives = 57/127 (44%), Gaps = 1/127 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDLALLVHGSSKVTRS 269
           A + +    L H         L + A K+E AC  T++ GK +TKDL     G+SK   S
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIETACFATIKDGKSLTKDLG----GNSKC--S 352

Query: 268 DYLNTEE 248
           D+  TEE
Sbjct: 353 DF--TEE 357
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>LEU3_SHEON (Q8E9N3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 39/131 (29%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH  ID+     L+    + V  C N  GD+ SD +A   GS+GL++S  M   G  +  
Sbjct: 220 EHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGL-F 278

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E A G+           G+   N IA I +    L H  K +      E A  +E A   
Sbjct: 279 EPAGGSAP------DIAGKGIANPIAQILSAALMLRHSLKQE------EAASAIERAVTK 326

Query: 340 TVESGKMTKDL 308
            + SG +T +L
Sbjct: 327 ALNSGYLTGEL 337
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>LEU3_RHIME (Q92KY8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 42/135 (31%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           N  GD+ SD  A   GSLG++ S  L  PD KT + +A +  V  H       G    N 
Sbjct: 246 NLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKALYEPV--HGSAPDIAGTGVANP 303

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 269
           IA I ++   L +      +  L++ A  LE+A    ++ G  T D  ++  G  KV   
Sbjct: 304 IAMIASFAMCLRY------SFNLVKEADDLEKAIANVLDQGIRTGD--IMAEGCRKV--- 352

Query: 268 DYLNTEEFIDAVAAE 224
               T E  DA+ AE
Sbjct: 353 ---GTAEMGDAILAE 364
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>LEU3_BUCUE (Q9EVH5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+ +   +K    + V  C N  GD+ SD  A   GS+G++ S  +      +  E
Sbjct: 223 HLYIDNAIMQIIKDPSQFDVILCSNLFGDIVSDECAAITGSIGMLPSASLNEKNFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + H         L + A K++E+ V  
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSVSMLVRH------GMNLKKIADKIDESVVSV 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T D++   H        +YL T E  D +A
Sbjct: 330 LKQGYRTADISNNSH--------NYLKTSEMGDIIA 357
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>LEU3_PHOPR (Q6LV25) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 1/157 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNQE-KFGMYE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N +A I   +  L  R  LD+     + A+ +E+A    
Sbjct: 282 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLDEE----KAARAIEQAVSQA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
           +E+G++T DLA          +   L+T E  D +AA
Sbjct: 330 LEAGELTADLA---------GKGAALSTSEMGDKIAA 357
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>IDH3A_MOUSE (Q9D6R2) Isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 366

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   G LG+  S  +  +G  I  E+ HGT           G+   N  
Sbjct: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGK-MTKDL 308
           A + +    L H         L + A K+E AC  T++ GK +TKDL
Sbjct: 306 ALLLSAVMMLRHMG-------LFDHAAKIEAACFATIKDGKSLTKDL 345
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>LEU3_NEIMB (Q9JZI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V A  N  GD+ SD  +   GS+G++ S  +  +GK +  E
Sbjct: 219 HMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YE 277

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            +HG+           G+   N +A+I +    L  R  L+D AR    AQ++E A    
Sbjct: 278 PSHGSAP------DIAGQNKANPLATILSLAMLL--RYSLNDEAR----AQQVENAVQKV 325

Query: 337 VESGKMTKDL 308
           ++ G  T D+
Sbjct: 326 LQQGLRTSDI 335
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>LEU3_HAEIN (P43860) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH  ID+     +KS   + V  C N  GD+ SD  A   GS+G++ S  +  +G  +  
Sbjct: 221 EHIYIDNATMQLIKSPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-Y 279

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E A G+           G+   N IA I +    L +   L+      E A  +E A   
Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQK 327

Query: 340 TVESGKMTKDLA 305
            + SG  T DLA
Sbjct: 328 VLASGHRTADLA 339
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>LEU3_BUCUA (Q9EVG6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 38/157 (24%), Positives = 67/157 (42%), Gaps = 1/157 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 223 HLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +      +  L + A K++++ +  
Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSLSMLVRY------SMNLKKIADKIDQSVISV 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
           ++ G  T D++           +DYL T E  D +A+
Sbjct: 330 LKKGYRTADIS---------NNNDYLKTNEMGDVIAS 357
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>LEU3_BACSU (P05645) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 1/159 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D+     + +   + V   +N  GD+ SD  +   GSLG++ S  +   G  +  
Sbjct: 219 EHMLVDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHL-F 277

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N  A+I      L+    L  +  L E A+ +E+A   
Sbjct: 278 EPVHGSAP------DIAGKGMANPFAAI------LSAAMLLRTSFGLEEEAKAVEDAVNK 325

Query: 340 TVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224
            + SGK T+DLA      S+   S    TEE   A+ +E
Sbjct: 326 VLASGKRTRDLA-----RSEEFSSTQAITEEVKAAIMSE 359
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>IDH3A_DROME (Q9VWH4) Probable isocitrate dehydrogenase [NAD] subunit alpha,|
           mitochondrial precursor (EC 1.1.1.41) (Isocitric
           dehydrogenase) (NAD(+)-specific ICDH)
          Length = 377

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 39/135 (28%), Positives = 57/135 (42%), Gaps = 2/135 (1%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530
           I +E + +D +    +++ G Y V    N  GD+ SD  A   G LGL  S  M  +G  
Sbjct: 241 IQFEEKYLDTVCLNMVQNPGKYDVLVMPNLYGDILSDMCAGLVGGLGLTPSGNMGLNGAL 300

Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
              E+ HGT           G+   N  A + +    L H         L  +A K+E A
Sbjct: 301 F--ESVHGTAP------DIAGKDLANPTALLLSAVMMLRH-------MELNTYADKIERA 345

Query: 349 CVGTVESGK-MTKDL 308
              T++ GK +T DL
Sbjct: 346 AFETIKEGKYLTGDL 360
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>LEU3_WOLSU (Q7M886) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 38.1 bits (87), Expect = 0.028
 Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +++   + V    N  GD+ SD  +   GS+GL+ S  +   GK    E
Sbjct: 216 HMYIDNAAMQLIRNPKQFDVILTGNLFGDILSDEASMLSGSIGLLPSASI--GGKAALYE 273

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+           G+   N IA+I + +  L H      +   +E A  +++A V T
Sbjct: 274 PIHGSAP------DIAGQGIANPIATIASASMMLRH------SLGEVEAADAIDKAIVKT 321

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNT 254
           ++ G  TKD+A    G+ ++  +D + +
Sbjct: 322 LKEGYRTKDIA--AFGAKEICTTDEMGS 347
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>LEU3_RHILO (Q98E57) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 38.1 bits (87), Expect = 0.028
 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 1/107 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           N  GD+ SD  A   GS+G++ S  L  PD KT + +A +  V  H       G+   N 
Sbjct: 246 NLFGDMLSDIAAMLTGSIGMLPSASLGAPDVKTKKRKALYEPV--HGSAPDIAGKGIANP 303

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           IA I ++   L +   + D       A +LE A    ++ G  TKD+
Sbjct: 304 IAMIASFAMCLRYSFGMVDE------ADRLEGAIAAVLDQGLRTKDI 344
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>LEU3_NEIMA (Q9JU79) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V A  N  GD+ SD  +   GS+G++ S  +  +GK +  E
Sbjct: 219 HMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YE 277

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            +HG+           G+   N +A++ +    L  R  L+D AR    AQ++E A    
Sbjct: 278 PSHGSAP------DIAGQNKANPLATVLSLAMLL--RYSLNDEAR----AQQVENAVQKV 325

Query: 337 VESGKMTKDL 308
           ++ G  T D+
Sbjct: 326 LQQGLRTGDI 335
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>LEU3_SHIDS (Q32K21) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 43/156 (27%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A  +E A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T+DLA    G++ V      +T+E  D +A
Sbjct: 330 LEEGIRTRDLA---RGAAAV------STDEMGDIIA 356
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>LEU3_BUCUO (Q9EVI1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 38/156 (24%), Positives = 67/156 (42%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+ +   +K+   + V  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 224 HLYIDNAIMQIIKNPNQFDVLLCPNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +   L D       A K++++ +  
Sbjct: 283 PAGGSAP------DIAGKNIANPIAQILSLSMLVRYGMNLKD------IADKIDKSVLSV 330

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T D++           ++YL T E  D +A
Sbjct: 331 LKKGYRTADIS---------NNNNYLKTNEMGDVIA 357
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>LEU3_SALTY (P37412) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I   +  L  R  LD N    + A  +E+A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 330 LEEGVRTGDLA---RGAAAV------STDEMGDIIA 356
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>LEU3_SALPA (Q5PDG2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I   +  L  R  LD N    + A  +E+A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 330 LEEGVRTGDLA---RGAAAV------STDEMGDIIA 356
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>LEU3_SALCH (Q57TE7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 45/156 (28%), Positives = 66/156 (42%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I   +  L  R  LD N    + A  +E+A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQIL--SLALLLRYSLDAN----DAATAIEQAINRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 330 LEEGVRTGDLA---RGAAAV------STDEMGDIIA 356
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>LEU3_BACHD (Q9K8E9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D+     ++    + V   +N  GD+ SD  +   GSLG++ S  +  DG  +  
Sbjct: 218 EHMLVDNAAMQLIRRPKQFDVLVTENLFGDILSDEASMVTGSLGMLPSASLTSDGPGL-Y 276

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N +A+I +    L +   L + A+       +E+A   
Sbjct: 277 EPIHGSAP------DIAGKGVANPLATIASCAMMLKYSFGLHEEAK------TIEDAIEA 324

Query: 340 TVESGKMTKDLA 305
            ++ G  T D+A
Sbjct: 325 VLKQGYRTADIA 336
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>LEU3_COLP3 (Q47WG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 37.4 bits (85), Expect = 0.048
 Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH  +D+     ++    + V  C N  GD+ SD  A   GS+GL+ S  +  DG  +  
Sbjct: 219 EHLYVDNAAMQLVRDPNQFDVMLCPNLFGDILSDICAMITGSMGLLPSASLNSDGFGM-Y 277

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E A G+           G    N IA I   +  L  R  L+  A     A+ +E+A   
Sbjct: 278 EPAGGSAP------DIAGLGVANPIAQIL--SAALMLRYSLNQGAA----AKAIEDAVSN 325

Query: 340 TVESGKMTKDL 308
            +++G +T DL
Sbjct: 326 ALDNGVLTADL 336
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>LEU3_NEIG1 (Q5F8T6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 37.0 bits (84), Expect = 0.062
 Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V A  N  GD+ SD  +   GS+G++ S  +  +GK +  E
Sbjct: 219 HMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGL-YE 277

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            +HG+           G+   N +A+I +    L  R  L+D AR    AQ++E +    
Sbjct: 278 PSHGSAP------DIAGQNKANPLATILSLAMLL--RYSLNDEAR----AQQVENSVQKV 325

Query: 337 VESGKMTKDL 308
           ++ G  T D+
Sbjct: 326 LQQGLRTGDI 335
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>LEU3_PASMU (Q9CJN6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 37.0 bits (84), Expect = 0.062
 Identities = 43/157 (27%), Positives = 63/157 (40%), Gaps = 1/157 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           +H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  
Sbjct: 221 DHIYIDNATMQLIKQPEFFDVLLCSNIFGDIISDECAMITGSMGMLPSASLNEKGFGL-Y 279

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E A G+           G+   N IA I +    L H   L+D A  +E A K       
Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRHSFNLNDAATAIENAVK------N 327

Query: 340 TVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
            +  G  T DLA           S  L+T++  D +A
Sbjct: 328 VLAEGHRTADLA---------DESQPLSTKQMGDLIA 355
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>LEU3_LEPIN (P24015) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 37.0 bits (84), Expect = 0.062
 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 1/141 (0%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           K E + +   H  +D+     + +   + V  C+N  GD+ SD  +   GS+G++ S  +
Sbjct: 211 KKEFSDVQLNHLYVDNAAMQLIVNPKQFDVVLCENMFGDILSDEASIITGSIGMLPSASL 270

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
              G  +  E + G+           G+   N IA + +    L +   +++ A      
Sbjct: 271 SESGFGLY-EPSGGSAP------DIAGKGVANPIAQVLSAALMLRYSFSMEEEAN----- 318

Query: 367 QKLEEACVGTVESGKMTKDLA 305
            K+E A   T+ SGK T+D+A
Sbjct: 319 -KIETAVRKTIASGKRTRDIA 338
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>LEU3_LEPIC (Q72RH7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 37.0 bits (84), Expect = 0.062
 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 1/141 (0%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           K E + +   H  +D+     + +   + V  C+N  GD+ SD  +   GS+G++ S  +
Sbjct: 211 KKEFSDVQLNHLYVDNAAMQLIVNPKQFDVVLCENMFGDILSDEASIITGSIGMLPSASL 270

Query: 547 CPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
              G  +  E + G+           G+   N IA + +    L +   +++ A      
Sbjct: 271 SESGFGLY-EPSGGSAP------DIAGKGVANPIAQVLSAALMLRYSFSMEEEAN----- 318

Query: 367 QKLEEACVGTVESGKMTKDLA 305
            K+E A   T+ SGK T+D+A
Sbjct: 319 -KIETAVRKTIASGKRTRDIA 338
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>LEU3_RHOPA (Q6ND82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 36.6 bits (83), Expect = 0.082
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           N  GD+ SD  A   GSLG++ S  +   D KT + ++ +  V  H       G+   N 
Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGEVDAKTGKRKSMYEPV--HGSAPDIAGKGMANP 303

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           +A + ++  G+A R  LD  A     A KL+EA    +  G  T D+
Sbjct: 304 VAMLASF--GMALRYSLDMGA----LADKLDEAIAAVLAKGLRTADI 344
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>LEU3_YERPE (Q8ZIG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 36.6 bits (83), Expect = 0.082
 Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + T  L      DD       A  +E A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLTLLLRFSLGKDD------AADAIERAINQA 329

Query: 337 VESGKMTKDLA 305
           +E G  T DLA
Sbjct: 330 LEQGYRTADLA 340
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>LEU3_VIBPA (Q87SS8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 36.6 bits (83), Expect = 0.082
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N +A I   +  L  R  L + A     AQ +E A    
Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIESAVSKA 330

Query: 337 VESGKMTKDLA 305
           + +G++T DLA
Sbjct: 331 LSAGELTADLA 341
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>LEU3_BRUSU (Q8FVF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           N  GD+ SD  A   GSLG++ S  L   D KT + +A +  V  H       G+   N 
Sbjct: 246 NLFGDLLSDVAAMLTGSLGMLPSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANP 303

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 269
           IA I +    L +      +  L+  A +LE A  G ++ G  T D  +   G++KV   
Sbjct: 304 IAMIASLAMCLRY------SFGLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV--- 352

Query: 268 DYLNTEEFIDAVAAE 224
               T E  DA+ A+
Sbjct: 353 ---GTTEMGDAILAK 364
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>LEU3_BRUME (Q8YCX4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 1/135 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           N  GD+ SD  A   GSLG++ S  L   D KT + +A +  V  H       G+   N 
Sbjct: 246 NLFGDLLSDVAAMLTGSLGMLPSASLGAADSKTGKRKALYEPV--HGSAPDIAGKGIANP 303

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTRS 269
           IA I +    L +      +  L+  A +LE A  G ++ G  T D  +   G++KV   
Sbjct: 304 IAMIASLAMCLRY------SFGLVAEADRLEAAIAGVLDDGIRTAD--IWSEGNTKV--- 352

Query: 268 DYLNTEEFIDAVAAE 224
               T E  DA+ A+
Sbjct: 353 ---GTTEMGDAILAK 364
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>LEU3_CAUCR (Q9ABN3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 350

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 1/138 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E   +  EH L D+     +++   + V    N  GD+ SD  A   GSLG++ S  +  
Sbjct: 208 EYPDVQLEHILADNCAMQLVRAPKQFDVIVTDNLFGDILSDAAAMLTGSLGMLPSAALGA 267

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
            GK    E  HG+           G+   N +A+I ++   L    K        E A  
Sbjct: 268 PGKPGLYEPIHGSAP------DIAGKGLANPLAAILSFEMALRWSLK------QTEAADA 315

Query: 361 LEEACVGTVESGKMTKDL 308
           L  A    +++G  T+DL
Sbjct: 316 LLAAVKAALDNGARTRDL 333
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>LEU3_HAEI8 (Q4QLS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 1/132 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH  ID+     +K+   + V  C N  GD+ SD  A   GS+G++ S  +   G  +  
Sbjct: 221 EHIYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEAGFGL-Y 279

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E A G+           G+   N IA I +    L +   L+      E A  +E A   
Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAADAIESAVQK 327

Query: 340 TVESGKMTKDLA 305
            + SG  T DLA
Sbjct: 328 VLASGHRTADLA 339
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>LEU3_VIBVY (Q7MP78) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N +A I   +  L  R  L + A     AQ +E A    
Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQA 330

Query: 337 VESGKMTKDLA 305
           + +G++T DLA
Sbjct: 331 LAAGELTADLA 341
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>LEU3_VIBVU (Q8DEE0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDIISDECAMITGSMGMLPSASL-NESKFGLYE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N +A I   +  L  R  L + A     AQ +E A    
Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----AQDIENAVSQA 330

Query: 337 VESGKMTKDLA 305
           + +G++T DLA
Sbjct: 331 LAAGELTADLA 341
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>LEU3_VIBCH (Q9KP82) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 37/131 (28%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  M  + K    E
Sbjct: 224 HMYIDNATMQLIKDPAQFDVMLCSNIFGDILSDECAMITGSMGMLPSASM-NESKFGLYE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N +A I   +  L  R  L + A     A+ +E A    
Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEEAA----ARDIENAVSQA 330

Query: 337 VESGKMTKDLA 305
           + +G++T DLA
Sbjct: 331 LAAGELTADLA 341
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>LEU3_SHIFL (Q83SP1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A  +E A    
Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 328

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
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>LEU3_ERWCT (Q6D0G7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 41/156 (26%), Positives = 62/156 (39%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HLYIDNATMQLIKDPSQFDVMLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A+ +E+A    
Sbjct: 282 PAGGSAP------DIAGKDIANPIAQILSLALLLRYSLGADD------AAEAIEKAVNTA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +  G  T DLA         + S+ + T E  D +A
Sbjct: 330 LAEGYRTADLA---------SASNAIGTSEMGDVIA 356
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>LEU3_ECOL6 (Q8FL76) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A  +E A    
Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 328

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
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>LEU3_ECO57 (Q8X9Z9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A  +E A    
Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AASAIERAINRA 328

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
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>LEU3_BUCUS (Q9EVI4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 37/157 (23%), Positives = 66/157 (42%), Gaps = 1/157 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K+   + +  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 223 HLYIDNATMQIIKNPNQFDILLCSNLFGDIISDECAMITGSIGMLPSASL-NEKKFGLYE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +      +  L   A K++++ +  
Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------SMNLKTIADKIDQSVISV 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
           ++ G  T D++           S YL T E  D +A+
Sbjct: 330 LKKGYRTADIS---------NNSHYLKTNEMGDVIAS 357
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>LEU3_DESPS (Q6ANR1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 40/138 (28%), Positives = 56/138 (40%)
 Frame = -2

Query: 640 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 461
           V  C N  GD+ SD  A   GS+GL+ S  +  +   +  E A G+           G+ 
Sbjct: 239 VMLCGNMFGDIISDEAAMLTGSMGLLASASLNTENFGL-FEPAGGSAP------DIAGQG 291

Query: 460 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 281
             N IA I +    L +           E A  +E A   T++ G  T D+A        
Sbjct: 292 IANPIAEILSAAMMLRYSLGYG------EAADAIEAAVEKTLDRGICTADIA-------- 337

Query: 280 VTRSDYLNTEEFIDAVAA 227
           V RS  +NT E  DA+ A
Sbjct: 338 VDRSQAVNTAEMGDAIVA 355
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>LEU3_BACCZ (Q63DX7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D      +++ G + V   +N  GD+ SD  +   GSLG++ S      G ++  
Sbjct: 210 EHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-Y 268

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N IA +    R +A    L  +  L      +EEA   
Sbjct: 269 EPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGCAIEEAISA 316

Query: 340 TVESGKMTKDL 308
            ++SGK T+D+
Sbjct: 317 VLKSGKCTEDI 327
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>LEU3_BACCR (Q81G11) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D      +++ G + V   +N  GD+ SD  +   GSLG++ S      G ++  
Sbjct: 210 EHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-Y 268

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N IA +    R +A    L  +  L      +EEA   
Sbjct: 269 EPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGYAIEEAVSA 316

Query: 340 TVESGKMTKDL 308
            ++SGK T D+
Sbjct: 317 VLKSGKCTADI 327
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>LEU3_SYMTH (Q67JY2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 368

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 38/141 (26%), Positives = 54/141 (38%), Gaps = 9/141 (6%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM--------C 545
           EH L D+     L+  G + V    N  GD  SD  A   GS+GL+ S  +         
Sbjct: 223 EHLLADNAAMQILRRPGDFDVMLASNLFGDFLSDEAAMLTGSIGLLPSASLGAARNRFGL 282

Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365
           P G     E  HG+           G+   N +A+I      L H    +D AR      
Sbjct: 283 PKG---FYEPIHGSAP------DIAGQDRANPLAAILCGAMLLRHSLGREDAAR------ 327

Query: 364 KLEEACVGTVESGKMTKDLAL 302
            +E+A    +E G  T D+ +
Sbjct: 328 AVEQAVAAVLEEGLRTADITV 348
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>LEU3_PHOLL (Q7N128) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 41/148 (27%), Positives = 61/148 (41%), Gaps = 1/148 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVMLCSNIFGDILSDECAMITGSMGMLPSASLNEKGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I   +  L  R  L  N    + A  +E+A    
Sbjct: 282 PAGGSAP------DIAGKGIANPIAQIL--SAALLLRYSLGHN----DAANAIEQAVNYA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNT 254
           +E G  T DLA    G+ K   +D + +
Sbjct: 330 LEQGYRTTDLA----GNGKAISTDEMGS 353
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>LEU3_BUCDN (O85071) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID++    +K    + V  C N  GD+ SD  A   GS+G++ S  +      +  E
Sbjct: 223 HLYIDNVCMQIIKDPNQFDVLLCSNLFGDIISDECAMITGSIGMLPSASLNEKNFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +   L+      + A K++ A +  
Sbjct: 282 PAGGSAP------DIQGKNIANPIAQILSLSMLIRYSMNLN------KIANKIDNAVINV 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T D++            +YL T E  D +A
Sbjct: 330 LKKGYKTMDIS---------KDQNYLKTNEMGDVIA 356
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>LEU3_VIBF1 (Q5E857) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +      +  E
Sbjct: 224 HMYIDNATMQLIKDPSQFDVMLCSNIFGDIISDECAMITGSMGMLPSASLNESNFGL-YE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N +A I   +  L  R  L +     E AQ +E A    
Sbjct: 283 PAGGSAP------DIAGKNIANPVAQIL--SAALMLRYSLGEE----EAAQSIEAAVSKA 330

Query: 337 VESGKMTKDLA 305
           + +G++T DLA
Sbjct: 331 LSAGELTADLA 341
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>LEU3_BUCUH (Q9EVH8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 37/156 (23%), Positives = 68/156 (43%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K+   + V  C N  GD+ SD  A   GS+G++ S         +  E
Sbjct: 223 HLYIDNATMQIIKNPNQFDVLLCSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+ + N IA I + +  + +  KL+      + A K+++A   +
Sbjct: 282 PAGGSAP------DIAGKNTANPIAQILSLSMLVRYGMKLN------KIADKIDDAVALS 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +++G  T D++           +++L T E  D +A
Sbjct: 330 LKAGYRTADIS---------NDNNFLKTNEMGDVIA 356
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>LEU3_BRAJA (Q89X19) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 2/141 (1%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           K E   +  EH+L D      +K    + V    N  GD+ SD  A   GSLG++ S  +
Sbjct: 212 KREYPDVTLEHQLADSGGMMLVKWPKQFDVIVTDNLFGDMLSDIAAMLTGSLGMLPSASL 271

Query: 547 CP-DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEF 371
              D K+ + +A +  V  H       G+   N IA I ++  G+A R   D  A     
Sbjct: 272 GEVDVKSKKRKALYEPV--HGSAPDIAGKGLANPIAMISSF--GMALRYSFDMGA----L 323

Query: 370 AQKLEEACVGTVESGKMTKDL 308
           A K++ A    + SG  T D+
Sbjct: 324 ADKVDAAIAAVLASGLRTADI 344
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>LEU3_BACHK (Q6HLF2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D      +++ G + V   +N  GD+ SD  +   GSLG++ S      G ++  
Sbjct: 210 EHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-Y 268

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N IA +    R +A    L  +  L      +EEA   
Sbjct: 269 EPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGCAIEEAISA 316

Query: 340 TVESGKMTKDL 308
            ++SGK T D+
Sbjct: 317 VLKSGKCTADI 327
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>LEU3_BACAN (Q81T67) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D      +++ G + V   +N  GD+ SD  +   GSLG++ S      G ++  
Sbjct: 210 EHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-Y 268

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N IA +    R +A    L  +  L      +EEA   
Sbjct: 269 EPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGCAIEEAISA 316

Query: 340 TVESGKMTKDL 308
            ++SGK T D+
Sbjct: 317 VLKSGKCTADI 327
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>LEU3_BUCTS (O31292) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
 Frame = -2

Query: 721 YEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545
           Y+   +  EH  ID+     +K+   + V  C N  GD+ SD  A   GS+GL+ S  + 
Sbjct: 214 YKFPNVKLEHMYIDNATMELIKNPSSFDVILCSNLFGDIISDECAAIIGSIGLLPSASLN 273

Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFA 431
             G  +  E A G+           G+T  N IA I +
Sbjct: 274 KSGFGL-YEPAGGSAP------NIAGKTIANPIAQILS 304
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>LEU3_GEOKA (Q5KWJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 371

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 1/132 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D+     +++   + V   +N  GD+ SD  +   GSLG++ S  +   G ++  
Sbjct: 219 EHMLVDNAAMQLIRAPKQFDVIVTENMFGDILSDEASMLSGSLGMLPSASLSASGPSL-Y 277

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G    N IA+I      L+    L  +  L   A+ +E A   
Sbjct: 278 EPVHGSAP------DIAGMNKANPIAAI------LSAAMMLRLSFGLTAEAEAVEHAVRQ 325

Query: 340 TVESGKMTKDLA 305
            ++ G  T DLA
Sbjct: 326 ALDQGLRTADLA 337
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>LEU3_SHISS (Q3Z5T7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A  +E A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 330 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 356
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>LEU3_ECOLI (P30125) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 222 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 280

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A  +E A    
Sbjct: 281 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRA 328

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 329 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 355
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>LEU3_ZYMMO (Q5NPQ9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 349

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V    N  GD+ SD  +   GS+GL+ S  +  +GK +  E
Sbjct: 215 HMYVDNAAMQLVRAPDQFDVIVTGNLFGDILSDLASACVGSIGLLPSASLNSEGKGL-YE 273

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+           G    N +A+I +    L +  K + +      A ++E+A    
Sbjct: 274 PIHGSAP------DIAGLGKANPLATILSGAMMLRYSLKREAD------ADRIEKAVSTA 321

Query: 337 VESGKMTKDL 308
           +E G  T DL
Sbjct: 322 LEKGARTADL 331
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>LEU3_ARCFU (O29627) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 326

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 33/106 (31%), Positives = 44/106 (41%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   G LGL  S  +    +T   E  HG     F +  KG    T  I
Sbjct: 218 NMFGDIVSDLAAGLVGGLGLAPSANV--GERTAIFEPVHGAA---FDIAGKGIANPTAMI 272

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
            +     R   +          +E A+K+EEA   T++ GK T DL
Sbjct: 273 LTACMMLRHFGY----------VEEAKKVEEAVEKTIKEGKKTPDL 308
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>LEU3_SULSO (Q9UXB2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 336

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 2/143 (1%)
 Frame = -2

Query: 700 YEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIE 524
           +E   +D   A  ++    + V    N  GD+ SD  +Q  GSLGL  S  +  D K++ 
Sbjct: 195 FEEMYVDAAAANLVRDPTRFDVIVTSNVYGDILSDEASQIAGSLGLAPSANI-GDRKSM- 252

Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACV 344
            E  HG     F +  KG     N  A + + +  L+   +L    + +  ++ LE A +
Sbjct: 253 FEPVHGAA---FDIAGKG---IANPTAFLLSVSMMLSRMYELSKENKYILASKSLENAII 306

Query: 343 GTVESG-KMTKDLALLVHGSSKV 278
            T +SG K+T+D    V GS+K+
Sbjct: 307 ETYKSGNKLTED----VGGSAKL 325
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>LEU3_METTH (O27441) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 329

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 34/106 (32%), Positives = 43/106 (40%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   G LGL  S  +    K    E  HG+        Q  G+   N  
Sbjct: 220 NLFGDILSDEAAGLIGGLGLAPSANI--GEKNALFEPVHGSAP------QIAGKNIANPT 271

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           A I   T  L H  K  +       AQK+E+A   T+  G +T DL
Sbjct: 272 AMILTTTLMLKHLNKKQE-------AQKIEKALQKTLAEGLVTPDL 310
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>LEU3_BUCRP (P48572) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K+   + V  C N  GD+ SD  A   GS+G++ S  +    K    E
Sbjct: 223 HLYIDNACMQIIKNPSQFDVLLCSNIFGDIISDECAMITGSIGMLPSASL-NSKKFGLYE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + H   L+      E A K++ +    
Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSLSMLIRHSMNLN------EIADKIDSSVYRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +++G  T D++            +Y+ T E  D +A
Sbjct: 330 LKAGYRTLDIS---------DGKNYIKTNEMGDIIA 356
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>LEU3_GLOVI (Q7NFH4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 30/108 (27%), Positives = 46/108 (42%)
 Frame = -2

Query: 628 KNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           +N  GD+ SD  A   GS+G++ S  +   G  +  E  HG+           G+   N 
Sbjct: 245 ENMFGDILSDEAAMLTGSIGMLPSASLGSGGPGL-YEPVHGSAP------DIAGQDKANP 297

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 305
           +A + +    L H      + R  E AQ +E A    +E G  T D+A
Sbjct: 298 LAQVLSGAMLLRH------SLRQPEAAQAVERAVQTVLEQGYRTGDIA 339
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>LEU3_BUCUM (Q9EVG9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 34.7 bits (78), Expect = 0.31
 Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + +  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 225 HLYIDNATMQIIKDPNQFDILLCSNLFGDIVSDECAIITGSIGMLPSASL-NEKKFGLYE 283

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +         L + A K++++ +  
Sbjct: 284 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------GMNLKKIADKIDQSVISV 331

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T D++           ++YL T E  D +A
Sbjct: 332 LKKGYRTADIS---------NNNNYLKTNEMGDVIA 358
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>LEU3_SOLTU (P29696) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC|
           1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530
           I YE  +ID+     +K+   + V    N  GD+ SD  A   G LGL  S  +   G  
Sbjct: 230 IKYEEVVIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIA 289

Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
           + AEA HG+           G+   N  A + +    L H         L + A ++++A
Sbjct: 290 L-AEAVHGSAP------DIAGKNLANPTALLLSSVSMLRH-------LELHDKADRIQDA 335

Query: 349 CVGTVESGKM 320
            + T+  GK+
Sbjct: 336 ILKTIAGGKV 345
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>LEU3_NITWN (Q3SNU3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 370

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSV-LMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNS 449
           N  GD+ SD  A   GSLG++ S  L   D KT +  A +  V  H       G+   N 
Sbjct: 246 NLFGDMLSDIAAMLTGSLGMLPSASLGDTDPKTEKRRALYEPV--HGSAPDIAGQGLANP 303

Query: 448 IASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           IA + ++  G+A R   D      + A KL+ A    +  G  T DL
Sbjct: 304 IAMLASF--GMALRYSFDRG----DLADKLDAAIAAVLAKGLRTADL 344
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>LEU3_YERPS (Q66EM2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L      DD       A  +E A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLILLLRFSLGKDD------AADAIERAINQA 329

Query: 337 VESGKMTKDLA 305
           +E G  T DLA
Sbjct: 330 LEQGYRTADLA 340
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>LEU3_SHIBS (Q326G2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +   G  +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    DD       A  +E A    
Sbjct: 282 PAGGSAP------DITGKNIANPIAQILSLALLLRYSLDADD------AACAIERAINRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 330 LEEGIRTGDLA---RGAAAV------STDEMGDIIA 356
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>LEU3_SALTI (Q8Z9I1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 42/156 (26%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +      +  E
Sbjct: 223 HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQEFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    L +    D      E A  +E+A    
Sbjct: 282 PAGGSAP------DIAGKNIANPIAQILSLALLLRYSLDAD------EAATAIEQAINRA 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           +E G  T DLA    G++ V      +T+E  D +A
Sbjct: 330 LEEGVRTSDLA---RGAAAV------STDEMGDIIA 356
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>LEU3_STAHJ (Q4L7U1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 346

 Score = 34.3 bits (77), Expect = 0.40
 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 1/156 (0%)
 Frame = -2

Query: 721 YEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545
           +E   +   H L+D      +     + V   +N  GD+ SD  +   GSLGL  S    
Sbjct: 204 HEFPDVKVNHLLVDACSMQLISQPTNFDVIVTENLFGDILSDEASTIPGSLGLSPSASFS 263

Query: 544 PDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQ 365
            +G  +           +  +H    + +  ++A+ F     LA    L ++    + A 
Sbjct: 264 LEGPRL-----------YEPIHGSAPDIANQNLANPFGMILSLA--MCLRESFNFEDAAS 310

Query: 364 KLEEACVGTVESGKMTKDLALLVHGSSKVTRSDYLN 257
           +LE+A    ++ GK TKDL      +   T SD  N
Sbjct: 311 ELEQAVYQLIKDGKTTKDL------NGHYTTSDIFN 340
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>LEU3_BACSK (Q5WEN4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 1/139 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E   +   H L+D+     ++    + V   +N  GD+ SD  +   GSLGL+ S  M  
Sbjct: 211 EYPDVTLSHMLVDNAAMQLIRDPRQFDVIVTENLFGDILSDEASMITGSLGLLPSASM-N 269

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
             K    E  HG+           G  + N +A+I +    L +   L D A+ +E A  
Sbjct: 270 TSKVGLFEPVHGSAP------DIAGTGAANPLATILSAAMMLQYSFGLADEAKAIEVAVD 323

Query: 361 LEEACVGTVESGKMTKDLA 305
                   +  G  TKD+A
Sbjct: 324 ------RVLAQGVRTKDIA 336
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>LEU3_THIFE (Q56268) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V    N  GD+ SD  +Q  GS+G++ S  +  +G+ +  E
Sbjct: 218 HMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASL-GEGRAM-YE 275

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+           G+   N +A+I +    L H    +       +AQ++E A    
Sbjct: 276 PIHGSAP------DIAGQDKANPLATILSVAMMLRHSLNAE------PWAQRVEAAVQRV 323

Query: 337 VESGKMTKDLA 305
           ++ G  T D+A
Sbjct: 324 LDQGLRTADIA 334
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>LEU3_STAAW (Q8NVJ0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D    + + +   + V  C+N  GD+ SD  +   GSLGL  S     DG  +   
Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
                   +  +H    + +  ++A+ F     LA    L ++    + A +LE+     
Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319

Query: 337 VESGKMTKDL 308
           +E G+ T DL
Sbjct: 320 IEHGQTTADL 329
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>LEU3_STAAS (Q6G7Q0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D    + + +   + V  C+N  GD+ SD  +   GSLGL  S     DG  +   
Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
                   +  +H    + +  ++A+ F     LA    L ++    + A +LE+     
Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319

Query: 337 VESGKMTKDL 308
           +E G+ T DL
Sbjct: 320 IEHGQTTADL 329
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>LEU3_STAAN (P65101) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D    + + +   + V  C+N  GD+ SD  +   GSLGL  S     DG  +   
Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
                   +  +H    + +  ++A+ F     LA    L ++    + A +LE+     
Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319

Query: 337 VESGKMTKDL 308
           +E G+ T DL
Sbjct: 320 IEHGQTTADL 329
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>LEU3_STAAM (P65100) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D    + + +   + V  C+N  GD+ SD  +   GSLGL  S     DG  +   
Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
                   +  +H    + +  ++A+ F     LA    L ++    + A +LE+     
Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319

Query: 337 VESGKMTKDL 308
           +E G+ T DL
Sbjct: 320 IEHGQTTADL 329
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>LEU3_STAAC (Q5HEE3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 33.9 bits (76), Expect = 0.53
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D    + + +   + V  C+N  GD+ SD  +   GSLGL  S     DG  +   
Sbjct: 213 HLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
                   +  +H    + +  ++A+ F     LA    L ++    + A +LE+     
Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYSM 319

Query: 337 VESGKMTKDL 308
           +E G+ T DL
Sbjct: 320 IEHGQTTADL 329
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>LEU3_STRT2 (Q5M405) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E   +  EH+L+D      + +   + V   +N  GD+ SD  +   G+LG+M S     
Sbjct: 204 EFPDVTLEHQLVDSAAMIMITNPARFDVVVTENLFGDILSDESSVLPGTLGVMPSASHSE 263

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
           +G ++  E  HG+           G+   N I+ I      L+    L ++    E A+ 
Sbjct: 264 NGPSL-YEPIHGSAP------DIAGQGIANPISMI------LSVAMMLRESFNETEGAEL 310

Query: 361 LEEACVGTVESGKMTKDL 308
           +E A   T+  G +T+DL
Sbjct: 311 IENAVDKTLNQGILTRDL 328
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>LEU3_STRT1 (Q5LZF3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 1/138 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E   +  EH+L+D      + +   + V   +N  GD+ SD  +   G+LG+M S     
Sbjct: 204 EFPDVTLEHQLVDSAAMIMITNPARFDVVVTENLFGDILSDESSVLPGTLGVMPSASHSE 263

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
           +G ++  E  HG+           G+   N I+ I      L+    L ++    E A+ 
Sbjct: 264 NGPSL-YEPIHGSAP------DIAGQGIANPISMI------LSVAMMLRESFNETEGAEL 310

Query: 361 LEEACVGTVESGKMTKDL 308
           +E A   T+  G +T+DL
Sbjct: 311 IENAVDKTLNQGILTRDL 328
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>LEU3_MANSM (Q65V05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 1/132 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           E+  ID+     +K+   + V  C N  GD+ SD  A   GS+G++ S  +  +G  +  
Sbjct: 221 ENMYIDNATMQLIKAPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGL-Y 279

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E A G+           G+   N IA I +    L +   L+      E A  +E A   
Sbjct: 280 EPAGGSAP------DIAGKGIANPIAQILSAAMMLRYSFNLN------EAATAIENAVQK 327

Query: 340 TVESGKMTKDLA 305
            +  G  T DLA
Sbjct: 328 VLADGHRTGDLA 339
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>LEU3_BUCUD (Q9EVE1) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 36/156 (23%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + +  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 223 HLYIDNATMQIIKDPNQFDILLCSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +         L   A K++++ +  
Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------GMNLKTIADKIDQSVISV 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T D++           ++YL T E  D +A
Sbjct: 330 LKKGYRTADIS---------NNNNYLKTNEMGDVIA 356
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>LEU3_PELCD (Q3A3B2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 33.5 bits (75), Expect = 0.69
 Identities = 43/158 (27%), Positives = 63/158 (39%), Gaps = 1/158 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +K+   + V  C N  GD+ SD  A   GSLG++ S  +  +G     E
Sbjct: 223 HMYVDNAAMQLVKAPKQFDVLLCPNMFGDILSDEAAMLTGSLGMLPSASLA-EGSFGMYE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N +A I +    L +   L D A  +E   K  E C+  
Sbjct: 282 PAGGSAP------DIAGKNIANPVAQILSAAMLLRYSCGLADAADAVE---KAVENCLA- 331

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAAE 224
             +G  T D+     G   V      +T    DAV AE
Sbjct: 332 --AGLRTGDIYQDADGEQLV------STSAMGDAVVAE 361
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>LEU3_SYNY3 (P73960) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 33.1 bits (74), Expect = 0.90
 Identities = 29/106 (27%), Positives = 46/106 (43%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   GS+G++ S  +  DG  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGSDGPGL-FEPVHGSAP------DIAGQDKANPL 298

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           A +   +  +  R  LD      + A +LE+A    +E G  T D+
Sbjct: 299 AQVL--SAAMMLRYGLDQP----QAADRLEDAVKKVLEQGYRTGDI 338
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>LEU3_SYNEL (P59029) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 361

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 29/106 (27%), Positives = 45/106 (42%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   GS+G++ S  +   G  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGESGPAL-FEPVHGSAP------DIAGQDKANPL 298

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           A +   +  +  R  L+  A     AQ +EEA    ++ G  T DL
Sbjct: 299 AMVL--SAAMMLRYGLNQPAA----AQAIEEAITAVLDQGYRTGDL 338
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>LEU3_THEMA (Q9WZ26) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 33/107 (30%), Positives = 46/107 (42%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   GSLGL+ S      G     E A G+           G+   N I
Sbjct: 239 NMFGDILSDESAALPGSLGLLPSASF---GDKNLYEPAGGSAP------DIAGKNIANPI 289

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLA 305
           A I +    L H      +  ++E A+K+E A    +E G  T+D+A
Sbjct: 290 AQILSLAMMLEH------SFGMVEEARKIERAVELVIEEGYRTRDIA 330
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>LEU3_BACC1 (Q73B99) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 354

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH L+D      +++ G + V   +N  GD+ SD  +   GSLG++ S      G ++  
Sbjct: 210 EHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSL-Y 268

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N IA +    R +A    L  +  L      +EEA   
Sbjct: 269 EPIHGSAP------DIAGKNKANPIAMM----RSVA--MMLGQSFGLTREGCAIEEAISA 316

Query: 340 TVESGKMTKDL 308
            ++ GK T D+
Sbjct: 317 VLKLGKCTADI 327
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>LEU3_ANASP (Q8YXA2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 28/106 (26%), Positives = 46/106 (43%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   GS+G++ S  +   G  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDAAAMLTGSIGMLPSASLGASGPGV-FEPVHGSAP------DIAGQDKANPL 298

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           A +   +  +  R  LD      + A K+E+A +  +E G  T D+
Sbjct: 299 AQVL--SAAMMLRYALDQP----QAADKIEQAVLQVLEQGDRTGDI 338
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>LEU3_GLUOX (Q5FUG5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 369

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 5/124 (4%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLM 548
           K E   +   H L D+     ++    + V    N  GD+ SD  +   GSLG++ S  +
Sbjct: 213 KREYPDVQLSHMLADNCAMQLVRDPNQFDVIVTGNLFGDILSDLASMLTGSLGMLPSATL 272

Query: 547 CP---DGK-TIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARL 380
            P   DGK     E  HG+           G+   N +A I ++   L +     ++A L
Sbjct: 273 GPVRADGKRNALYEPIHGSAP------DIAGKGIANPLAQILSFAMLLRYSLNRAEDADL 326

Query: 379 LEFA 368
           +E A
Sbjct: 327 IEMA 330
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>LEU3_LACLA (Q02143) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH+L+D      + +   + V   +N  GD+ SD  +   GSLG+M S     +G  +  
Sbjct: 210 EHQLVDSCAMLLITNPQQFDVIVTENLFGDILSDEASSLAGSLGVMPSSSHGFNGLAL-Y 268

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N ++ I +    L      +D A +      +E+A   
Sbjct: 269 EPIHGSAP------DIAGKGIANPVSMILSIAMMLRESFGQEDGAAM------IEKAVTQ 316

Query: 340 TVESGKMTKDL 308
           T   G +TKDL
Sbjct: 317 TFTDGILTKDL 327
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>LEU3_BUCUN (Q9EVI7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 38/156 (24%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S  +  + K    E
Sbjct: 224 HLYIDNATMQIIKDPNQFDVLLCSNLFGDIISDECAIITGSIGMLPSASL-NEKKFGLYE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +      +  L   A K++ + +  
Sbjct: 283 PAGGSAP------DIEGKNIANPIAQILSVSMLVRY------SMNLKNIADKIDYSVISI 330

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T D+A           ++YL T E  D +A
Sbjct: 331 LKKGYKTADIA---------HDNNYLKTNEMGDVIA 357
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>LEU3_BUCBP (P59515) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 366

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +K+   + V  C N  GD+ SD  A   GS+GL+ S  +  D      E
Sbjct: 223 HLYVDNAAMQIIKNPSQFDVLLCSNLFGDILSDECAAITGSIGLLPSASL-NDKNFGLYE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I +    + +  KL D A L+++A         T
Sbjct: 282 PAGGSAP------DIKGKNIANPIALILSIGMMMRYSFKLYDVADLIDWAVN------KT 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T+D++           + ++NT    D +A
Sbjct: 330 LKLGYRTQDIS---------ENNKFINTSSMGDIIA 356
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>LEU3_PSEHT (Q3IJS3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 358

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 5/120 (4%)
 Frame = -2

Query: 640 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 461
           V  C N  GD+ SD  A   GS+GL+ S  +   G  +  E A G+           G+ 
Sbjct: 242 VLLCDNLFGDILSDECAMITGSMGLLPSASLNQSGFGL-YEPAGGSAP------DIAGKG 294

Query: 460 STNSIASIFAWTRGLAHRAKLDDNARLLEFA-QKLEEACVGTVE----SGKMTKDLALLV 296
             N IA I +    L +    D+ AR +E A  +   A VGT +    +G  T D+A  +
Sbjct: 295 VANPIAQILSAALMLRYSLGQDEAARTIEKAVAEAVAAGVGTPDIFPNAGYTTNDVAAAI 354
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>LEU3_GEOSL (Q748X2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 35/135 (25%), Positives = 57/135 (42%)
 Frame = -2

Query: 631 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 452
           C+N  GD+ SD  A   GSLG++ S  +  +G     E + G+           G+   N
Sbjct: 245 CENMFGDILSDEAAMLTGSLGMLPSASLA-EGTFGMYEPSGGSAP------DIAGQGIAN 297

Query: 451 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 272
            IA I      L+    L  +  +++ A  ++ A    ++ G  T+D+     G   V  
Sbjct: 298 PIAQI------LSMGMMLKFSFGMVDAADAIDNAVATVLDQGFRTRDIYQQKDGEKLV-- 349

Query: 271 SDYLNTEEFIDAVAA 227
               NT+E  DA+ A
Sbjct: 350 ----NTKEMGDAIIA 360
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>LEU3_RALSO (Q8XXX5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 356

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 15/138 (10%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +K+   + V    N  GD+ SD  A   GS+G++ S  +  + K +  E
Sbjct: 219 HMYVDNAAMQLVKAPKNFDVVVTGNMFGDILSDEAAMLTGSIGMLPSASLDANNKGL-YE 277

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFA------WTRGLAHRAKLDDNARLLEFAQK-- 362
            +HG+           G+   N +A+I +      +T G A +A   +NA     AQ   
Sbjct: 278 PSHGSAP------DIAGKGIANPLATILSAAMMLRYTLGKAEQADRIENAVKKVLAQGYR 331

Query: 361 ----LEEAC--VGTVESG 326
               L   C  VGTVE G
Sbjct: 332 TGDILTPGCKQVGTVEMG 349
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>LEU3_THET8 (Q5SIY4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH+ +D M  + ++S   + V    N  GD+ SD  +   GSLGL+ S  +     T   
Sbjct: 212 EHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL--GRGTPVF 269

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
           E  HG+           G+   N  A+I +    L H         L+E A+K+E+A
Sbjct: 270 EPVHGSAP------DIAGKGIANPTAAILSAAMMLEHA------FGLVELARKVEDA 314
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>LEU3_THET2 (P61494) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 1/117 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH+ +D M  + ++S   + V    N  GD+ SD  +   GSLGL+ S  +     T   
Sbjct: 212 EHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL--GRGTPVF 269

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
           E  HG+           G+   N  A+I +    L H         L+E A+K+E+A
Sbjct: 270 EPVHGSAP------DIAGKGLANPTAAILSAAMMLEHA------FGLVELARKVEDA 314
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>LEU3_METCA (Q606F4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 360

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 33/131 (25%), Positives = 55/131 (41%), Gaps = 1/131 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V    N  GD+ SD  A   GS+G++ S  +   GK +  E
Sbjct: 220 HMYVDNAAMQLVRNPKQFDVMLTDNMFGDILSDCAAMLTGSIGMLPSASLAESGKGM-YE 278

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+           G    N IA+I +    L  R   DD       A+++ +A    
Sbjct: 279 PIHGSAP------DIAGRGIANPIATILSLAMML--RYSFDDAVS----AERIGKAVQTA 326

Query: 337 VESGKMTKDLA 305
           ++ G  T D+A
Sbjct: 327 LDQGFRTADIA 337
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>IDH_ECOLI (P08200) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)|
           (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
           ICDH) (IDP)
          Length = 416

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 34/136 (25%), Positives = 52/136 (38%)
 Frame = -2

Query: 640 VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGET 461
           V AC N +GD  SD LA   G +G+     +  +      EA HGT  ++       G+ 
Sbjct: 298 VIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALF--EATHGTAPKY------AGQD 349

Query: 460 STNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSK 281
             N  + I +    L H           E A  + +   G + +  +T D   L+ G+  
Sbjct: 350 KVNPGSIILSAEMMLRHMG-------WTEAADLIVKGMEGAINAKTVTYDFERLMDGAK- 401

Query: 280 VTRSDYLNTEEFIDAV 233
                 L   EF DA+
Sbjct: 402 -----LLKCSEFGDAI 412
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>LEU3_NITOC (Q3JCC4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 362

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V    N  GD+ SD  A   GS+G++ S  +   G+ +  E
Sbjct: 220 HMYVDNAAMQLVRAPKQFDVVVTTNMFGDILSDCAAMLTGSIGMLPSASLDQSGRGM-YE 278

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+           G+   N +A+I +    L  R  LD  A+    A +LE+A    
Sbjct: 279 PIHGSAP------DIAGQGIANPLATILSVAMML--RYSLDSPAQ----ATRLEKAVGAV 326

Query: 337 VESGKMTKDL 308
           ++ G  T D+
Sbjct: 327 LDQGLRTPDI 336
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>ATG16_XENTR (Q5I0B9) Autophagy-related protein 16 (APG16-like 1)|
          Length = 537

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 7/83 (8%)
 Frame = -2

Query: 610 VQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTV-------TRHFRVHQKGGETSTN 452
           VQ  F A GF      T V+  PDG  + A +A GT+        +  R+  K   +S N
Sbjct: 452 VQQTFSAPGFKCGSDWTRVIFSPDGSYVSAGSAEGTLYFWNVLTGKVERMFSKQHSSSIN 511

Query: 451 SIASIFAWTRGLAHRAKLDDNAR 383
           ++    AW+    H   +D  +R
Sbjct: 512 AV----AWSPSGTHVVSVDKGSR 530
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>LEU3_OCEIH (Q8EN68) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 366

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 2/111 (1%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY--VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           + L+ D  A  L ++  +  V   +N  GD+ SD  +   GSLG++ S  +  DG  +  
Sbjct: 214 NHLLVDAAAMKLVTQPSFFDVIVTENLFGDILSDEASVLTGSLGMLPSASLRADGLGL-Y 272

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           E  HG+           G+   N +A I +    L H   L D A+ +E A
Sbjct: 273 EPVHGSAP------DIAGKGIANPLAMILSAALMLEHSFGLVDEAKEIERA 317
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>LEU31_DECAR (Q47HR1) 3-isopropylmalate dehydrogenase 1 (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase 1) (IMDH 1) (3-IPM-DH 1)
          Length = 350

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 1/157 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D+     +K+   + V    N  GD+ SD  +   GS+G++ S  +    K +  E
Sbjct: 213 HMLVDNAAMQLVKAPKQFDVMVTGNMFGDILSDEASMLTGSIGMLPSASLDDKNKGL-YE 271

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            +HG+           G+   N +A+I +    L +   L+      E A ++E A    
Sbjct: 272 PSHGSAP------DIAGKGVANPLATILSAAMMLRYTFGLE------EQALRVENAVKKV 319

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
           +  G  T D  +   G++KV       T E  DAV A
Sbjct: 320 LAQGYRTGD--IYERGTNKV------GTREMGDAVLA 348
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>LEU3_CEPAC (Q12545) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 380

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 3/120 (2%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY--VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMC 545
           E   I  +H+L D M    ++    +  V    N  GD+ SD      G+LGLM S  +C
Sbjct: 217 EFPDITLQHQLADSMAMLMVRDPRRFNGVIHTDNTFGDILSDISGAITGTLGLMPSASLC 276

Query: 544 PDGKTIEAEAAHGTVTR-HFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
             G   E   ++G     H       G+   N +A I +    L +   L+  A  +E A
Sbjct: 277 --GVPGEGHRSNGIYEPVHGSAPDISGKGLANPVAQILSVAMMLRYSMGLEKEATAVERA 334
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>OM25_BRUCA (Q45110) 25 kDa outer-membrane immunogenic protein precursor|
          Length = 213

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 34/131 (25%), Positives = 53/131 (40%), Gaps = 7/131 (5%)
 Frame = -2

Query: 679 DMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDGKTIEAEAAHGT 503
           D + Y ++ + GY WA K+ DG      + QGF GSL       + P    + A  A   
Sbjct: 87  DQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVMPYLTAGIAGSQ 142

Query: 502 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLEFAQKLEEACVG 341
           +  +   +   GE+          WT G    AKL DN       R  +++ K  +    
Sbjct: 143 IKLN---NGLDGESKFR-----VGWTAGAGLEAKLTDNILGRVEYRYTQYSNKNYDLAGT 194

Query: 340 TVESGKMTKDL 308
           TV +   T+D+
Sbjct: 195 TVRNKLDTQDI 205
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>LEU3_STAS1 (Q49Z13) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 346

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 3/132 (2%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D    + + +   + V   +N  GD+ SD  +   GSLGL  S      G  +  E
Sbjct: 213 HLLVDACAMHLITNPSQFDVIVTENLFGDILSDEASVIPGSLGLSPSASFSEQGPRLY-E 271

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAH--RAKLDDNARLLEFAQKLEEACV 344
             HG+            + +   IA+ F     +A   R  L+++    + A KLE    
Sbjct: 272 PIHGSAP----------DIANQDIANPFGMLLSVAMCLRESLNED----KAADKLENVIY 317

Query: 343 GTVESGKMTKDL 308
             ++ GK T+DL
Sbjct: 318 QLIKEGKTTRDL 329
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>LEU3_BURCE (Q845W3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 355

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 1/139 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E A +   H  +D+      K+   + V    N  GD+ SD  +   GS+G++ S  +  
Sbjct: 210 EYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDK 269

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
           + K +  E +HG+           G+   N +A+I      L+    L  +    E A +
Sbjct: 270 NNKGL-YEPSHGSAP------DIAGKGIANPLATI------LSAAMLLRYSLNRAEQADR 316

Query: 361 LEEACVGTVESGKMTKDLA 305
           +E A    +E G  T D+A
Sbjct: 317 IERAVKTVLEQGYRTGDIA 335
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>LEU3_PSYAR (Q4FRV0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 31.2 bits (69), Expect = 3.4
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 1/138 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E + +   H   D+     +K    + V    N  GD+ SD  A   GS+G++ S  +  
Sbjct: 218 EYSDVALSHMYADNACMQLIKDPKQFDVMVTGNLFGDILSDEAAMLTGSIGMLPSASLDE 277

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
            GK +  E  HG+           G+   N +A+I +    L +  K +        AQ 
Sbjct: 278 AGKGM-YEPCHGSAP------DIAGQDIANPLATILSVAMMLRYTFKQE------VAAQA 324

Query: 361 LEEACVGTVESGKMTKDL 308
           +E+A    ++ G  T D+
Sbjct: 325 IEQAVSDVLDDGLRTVDI 342
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>LEU3_STRR6 (Q8DPJ4) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 31/131 (23%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH+L+D      + +   + V   +N  GD+ SD  +   G+LG+M S     +G ++  
Sbjct: 211 EHQLVDSAAMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSL-Y 269

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E  HG+           G+   N I+ I      L+    L D+    E  ++++ A   
Sbjct: 270 EPIHGSAP------DIAGQGIANPISMI------LSVVMMLRDSFGRYEDTERIKRAVET 317

Query: 340 TVESGKMTKDL 308
           ++ +G +T+D+
Sbjct: 318 SLAAGILTRDI 328
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>LEU3_PROMT (Q46LE2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H+ +D+     +++   + V    N  GD+ SD  A   GS+G++ S  +  DG  +  E
Sbjct: 220 HQYVDNAAMQLVRNPSQFDVILTGNLFGDILSDIAAMLTGSIGMLPSASLTTDGPGV-FE 278

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+            + +   IA+  A     A   K+  N    E A  LE A    
Sbjct: 279 PVHGSAP----------DIAGKDIANPIAMLLSAAMMLKIALNE--TEAATFLENAINEI 326

Query: 337 VESGKMTKDL 308
           +  G  T DL
Sbjct: 327 LNDGYRTSDL 336
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>LEU3_ACIAD (Q6FEV6) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 359

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 15/143 (10%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530
           I   H  +D+     +++   + V    N  GD+ SD  A   GS+G++ S  +  +GK 
Sbjct: 217 IQLSHMYVDNAAMQLVRAPKQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSASLDENGKG 276

Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA--QKLE 356
           +  E  HG+           G+   N +A+I +    L +  + +  A+ +E A  Q L+
Sbjct: 277 M-YEPCHGSAP------DIAGQNVANPLATILSVAMMLRYTFREEAAAKAIEDAVGQVLD 329

Query: 355 EAC------------VGTVESGK 323
           +              VGTVE G+
Sbjct: 330 QGLRTADIMSEGMQRVGTVEMGQ 352
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>LEU3_PSEF5 (Q4KF05) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 360

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 38/157 (24%), Positives = 67/157 (42%), Gaps = 1/157 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V    N  GD+ SD  +   GS+G++ S  +  + K +  E
Sbjct: 220 HMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDEASMLTGSIGMLPSASLDANNKGM-YE 278

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+           G+   N +A+I + +  L +      +  L E A  +E+A    
Sbjct: 279 PCHGSAP------DIAGQGIANPLATILSVSMMLRY------SFNLTEAADAIEQAVSRV 326

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
           ++ G  T D  +   G +KV       T+E  DAV A
Sbjct: 327 LDQGLRTGD--IWSAGCTKV------GTQEMGDAVVA 355
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>LEU3_THEAQ (P24098) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 344

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 1/111 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           +H+ +D M  + +K+   + V    N  GD+ SD  +   GSLGL+ S  +     T   
Sbjct: 212 DHQYVDAMAMHLVKNPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL--GRGTPVF 269

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFA 368
           E  HG+           G+   N  A+I +    L H   L + AR +E A
Sbjct: 270 EPVHGSAP------DIAGKGIANPTAAILSAAMMLEHAFGLVELARRVEAA 314
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>LEU3_BURPS (Q63JL2) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 355

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 34/139 (24%), Positives = 57/139 (41%), Gaps = 1/139 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E A +   H  +D+      K+   + V    N  GD+ SD  +   GS+G++ S  +  
Sbjct: 210 EYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDQ 269

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
             K +  E +HG+           G+   N +A+I      L+    L  +    E A +
Sbjct: 270 RNKGL-YEPSHGSAP------DIAGKGIANPLATI------LSAAMLLRYSLNRAEQADR 316

Query: 361 LEEACVGTVESGKMTKDLA 305
           +E A    +E G  T D+A
Sbjct: 317 IERAVKAVLEQGYRTGDIA 335
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>LEU3_BURMA (Q62AI9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 355

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 34/139 (24%), Positives = 57/139 (41%), Gaps = 1/139 (0%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCP 542
           E A +   H  +D+      K+   + V    N  GD+ SD  +   GS+G++ S  +  
Sbjct: 210 EYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDQ 269

Query: 541 DGKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQK 362
             K +  E +HG+           G+   N +A+I      L+    L  +    E A +
Sbjct: 270 RNKGL-YEPSHGSAP------DIAGKGIANPLATI------LSAAMLLRYSLNRAEQADR 316

Query: 361 LEEACVGTVESGKMTKDLA 305
           +E A    +E G  T D+A
Sbjct: 317 IERAVKAVLEQGYRTGDIA 335
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>LEU3_SYNP6 (Q5MZ40) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 28/106 (26%), Positives = 46/106 (43%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   GS+G++ S  +  +G  +  E  HG+           G+   N +
Sbjct: 246 NLFGDILSDIAAMLTGSIGMLPSASLGAEGPGV-FEPVHGSAP------DIAGQDKANPL 298

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           A +   +  +  R  LD+     E A ++E A    ++ G  T DL
Sbjct: 299 AQVL--SAAMMLRYGLDEP----EAAARIEAAVNQVLDQGYRTGDL 338
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>LEU3_SILPO (Q5LWZ5) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 367

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 31/106 (29%), Positives = 43/106 (40%)
 Frame = -2

Query: 625 NYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTNSI 446
           N  GD+ SD  A   GSLG++ S  +         +A +  V  H       G+   N I
Sbjct: 244 NLFGDILSDCAAMLTGSLGMLPSASLGAPMANGRPKALYEPV--HGSAPDIAGQGKANPI 301

Query: 445 ASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDL 308
           A I ++   +A R   D  A     A +LE A    +  G  T DL
Sbjct: 302 ACILSF--AMALRYSFDQGAE----ADRLEAAVEQVLADGVRTADL 341
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>LEU3_BUCUL (Q9AQC8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH) (Fragment)
          Length = 126

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 31/134 (23%), Positives = 55/134 (41%)
 Frame = -2

Query: 631 CKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAHGTVTRHFRVHQKGGETSTN 452
           C N  GD+ SD  A   GS+G++ S         +  E A G+           G+   N
Sbjct: 8   CSNLFGDIISDECAVITGSIGMLPSASFNEKNFGL-YEPAGGSAP------DIAGKNIAN 60

Query: 451 SIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVESGKMTKDLALLVHGSSKVTR 272
            IA I + +  + +  KL       + A K++++    +++G  T D++           
Sbjct: 61  PIAQILSLSMLVRYGMKLK------KIADKIDKSVASALKAGYRTADIS---------NN 105

Query: 271 SDYLNTEEFIDAVA 230
           + YL T E  D ++
Sbjct: 106 NSYLKTNEMGDVIS 119
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>LEU3_PROMP (Q7V1R9) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 357

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 1/127 (0%)
 Frame = -2

Query: 685 IDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAEAAH 509
           +D+     +K  G + V    N  GD+ SD  A   GS+G++ S  +   G  +  E  H
Sbjct: 223 VDNAAMQLVKDPGQFDVILTSNLFGDILSDLAAMITGSIGMLPSASLSNSGPGV-FEPVH 281

Query: 508 GTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGTVES 329
           G+            + +  +IA+  A     +   K+  N   +E A  +E A    +  
Sbjct: 282 GSAP----------DIAGKNIANPIAMALSTSMMLKIGLNE--IEAADDIEIAIDNVLSK 329

Query: 328 GKMTKDL 308
           G  T DL
Sbjct: 330 GYRTSDL 336
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>INHBA_SHEEP (P43032) Inhibin beta A chain precursor (Activin beta-A chain)|
          Length = 425

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
 Frame = -2

Query: 523 AEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTR-GLAHRAKLDDNARLLEFAQKLEEAC 347
           AE+     T HF + Q+G + S    A I+ + +   A+R +     RL +  + L+   
Sbjct: 127 AESGTARKTLHFEISQEGSDLSVVERAEIWLFLKVPKANRTRSKVTIRLFQQQKHLQ--- 183

Query: 346 VGTVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDA 236
            G++++G+  +++ L      K  +S+ L +E+ +DA
Sbjct: 184 -GSLDAGEEAEEVGL------KGEKSEMLISEKVVDA 213
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>OM25_BRUSU (Q45689) 25 kDa outer-membrane immunogenic protein precursor|
          Length = 213

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 7/142 (4%)
 Frame = -2

Query: 712 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDG 536
           AG +       D + Y ++ + GY WA K+ DG      + QGF GSL       + P  
Sbjct: 76  AGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVM 131

Query: 535 KTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLE 374
             + A    G      +++    + S   +     WT G    AKL DN       R  +
Sbjct: 132 PYLTA----GIAGSQIKLNNGLDDESKFRV----GWTAGAGLEAKLTDNILGRVEYRYTQ 183

Query: 373 FAQKLEEACVGTVESGKMTKDL 308
           +  K  +    TV +   T+D+
Sbjct: 184 YGNKNYDLAGTTVRNKLDTQDI 205
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>OM25_BRUAB (Q44664) 25 kDa outer-membrane immunogenic protein precursor|
          Length = 213

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 7/142 (4%)
 Frame = -2

Query: 712 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDG 536
           AG +       D + Y ++ + GY WA K+ DG      + QGF GSL       + P  
Sbjct: 76  AGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVM 131

Query: 535 KTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLE 374
             + A    G      +++    + S   +     WT G    AKL DN       R  +
Sbjct: 132 PYLTA----GIAGSQIKLNNGLDDESKFRV----GWTAGAGLEAKLTDNILGRVEYRYTQ 183

Query: 373 FAQKLEEACVGTVESGKMTKDL 308
           +  K  +    TV +   T+D+
Sbjct: 184 YGNKNYDLAGTTVRNKLDTQDI 205
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>LEU3_NEILA (P50180) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH) (Fragment)
          Length = 313

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V A  N  GD+ SD  +   GSLG++ S  +  +GK +  E
Sbjct: 219 HMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSLGMLPSASLDENGKGL-YE 277

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA 386
            +HG+           G+   N +A+I +    L  R  L+D A
Sbjct: 278 PSHGSAP------DIAGQNKANPLATILSLAMLL--RYSLNDEA 313
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>LEU3_BACCA (P05644) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 366

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 25/96 (26%), Positives = 40/96 (41%)
 Frame = -2

Query: 718 EAAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPD 539
           E   +  EH L+D  +      +   V   +N  GD+ SD  +   GSLG++ S  +   
Sbjct: 211 EFPDVTLEHMLVDMRMQLIRAPKQFDVIVTENMFGDILSDEASMLSGSLGMLPSASLSAS 270

Query: 538 GKTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFA 431
           G ++  E  HG+           G    N IA+I +
Sbjct: 271 GPSL-YEPVHGSAP------DIAGMNKANPIAAILS 299
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>LEU3_BLOFL (Q7VQJ7) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 364

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 35/158 (22%), Positives = 65/158 (41%), Gaps = 1/158 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           +H  +D+     +++   + V  C N  GD+ SD  A+  GS+G++ S  +      +  
Sbjct: 223 QHLYVDNASMQLIRNPSAFDVILCPNLFGDILSDECAEINGSIGILPSASLNEHNFGL-Y 281

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVG 341
           E A G+           G+   N IA I +      +  KL+        A  +E+A   
Sbjct: 282 EPAGGSAP------DIAGKNIANPIAQILSTALLFRYSLKLN------HVAITIEKAVYK 329

Query: 340 TVESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
            +  G  T+D+A          +   +NT++  D +A+
Sbjct: 330 ALTLGYRTQDIA--------YNKQKSVNTDDMGDIIAS 359
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>Y1185_METJA (Q58585) Hypothetical protein MJ1185|
          Length = 622

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 22/62 (35%), Positives = 34/62 (54%)
 Frame = -3

Query: 543 LMVKQSKPKLPMAQSLVISVFTRKVVKPAQTALLPSLLGQEDLHTGQS*TTTLDFLNLHR 364
           L+V+  K +LP+ ++L I  F RK +KP    L+  LLG ED+          D +NL+R
Sbjct: 504 LVVESIKLELPI-ENLGICRFHRKWLKPVLKELVKELLGIEDI--------VEDSINLYR 554

Query: 363 NL 358
            +
Sbjct: 555 EI 556
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>LEU3_PICST (O94114) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 373

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 44/146 (30%), Positives = 60/146 (41%), Gaps = 7/146 (4%)
 Frame = -2

Query: 724 KYEAAGIWYEHRLIDDMVAYALKSE---GGYVWACKNYDGDVQSDFLAQGFGSLGLMTSV 554
           K E   +  +H+LID      ++S     G V    N  G + SD  +   GSLGL+ S 
Sbjct: 217 KEEFPQLTIQHQLIDSAAMILVQSPTKLNGIV-ITSNMFGYIISDEASVIPGSLGLLPSA 275

Query: 553 LMCPDGKTIEA----EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA 386
            +     T  A    E  HG+            E   N IA+I +    L  R  LD   
Sbjct: 276 SLASLPDTNSAFGLYEPCHGSAPDL-------PENKVNPIATILSVAMML--RLSLDS-- 324

Query: 385 RLLEFAQKLEEACVGTVESGKMTKDL 308
             L+ A+ LEEA    ++SG  T DL
Sbjct: 325 --LKEAEALEEAVRQVLDSGVRTADL 348
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>LEU3_THETN (Q8RDK0) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 355

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 39/155 (25%), Positives = 62/155 (40%), Gaps = 1/155 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +K+   + V    N  GD+ SD  AQ  GS+G++ S  +  D   +  E
Sbjct: 218 HMYVDNCAMQLVKNPFQFDVILTNNMFGDILSDEAAQIVGSIGILPSASLRGDRVGL-YE 276

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+           G+   N +A+I +    L +    +      E AQ + +A    
Sbjct: 277 PIHGSAP------DIAGKKIANPLATILSVAMMLQYSFGEE------EAAQDIRKAVERA 324

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
           +E G  T DL           +   L+TEE  D V
Sbjct: 325 LEEGFRTADLG----------KGIVLSTEEMGDKV 349
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>LEU3_THETH (P61495) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 345

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 1/117 (0%)
 Frame = -2

Query: 697 EHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEA 521
           EH+ +D    + ++S   + V    N  GD+ SD  +   GSLGL+ S  +     T   
Sbjct: 212 EHQYVDAAAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASL--GRGTPVF 269

Query: 520 EAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
           E  HG+           G+   N  A+I +    L H         L+E A+K+E+A
Sbjct: 270 EPVHGSAP------DIAGKGIANPTAAILSAAMMLEHA------FGLVELARKVEDA 314
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>OM25_BRUME (Q45321) 25 kDa outer-membrane immunogenic protein precursor|
          Length = 213

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 7/141 (4%)
 Frame = -2

Query: 712 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGF-GSLGLMTSVLMCPDG 536
           AG +       D + Y ++ + GY WA K+ DG      + QGF GSL       + P  
Sbjct: 76  AGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLE----VKQGFEGSLRARVGYDLNPVM 131

Query: 535 KTIEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNA------RLLE 374
             + A    G      +++    + S   +     WT G    AKL DN       R  +
Sbjct: 132 PYLTA----GIAGSQIKLNNGLDDESKFRV----GWTAGAGLEAKLTDNILGRVEYRYTQ 183

Query: 373 FAQKLEEACVGTVESGKMTKD 311
           +  K  +    TV +   T+D
Sbjct: 184 YGNKNYDLAGTTVRNKLDTQD 204
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>LYS12_YEAST (P40495) Homoisocitrate dehydrogenase, mitochondrial precursor (EC|
           1.1.1.87)
          Length = 371

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 32/128 (25%), Positives = 51/128 (39%), Gaps = 1/128 (0%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530
           I Y  +++D MV    +    + V    N  GD+ SD  A   GSLG++ S  + P+   
Sbjct: 235 IKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--I 292

Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
           +  E  HG+      +  KG      +I S       L H     D  + ++    L E 
Sbjct: 293 VIGEPCHGSAP---DIAGKGIANPIATIRSTALMLEFLGHNEAAQDIYKAVD--ANLREG 347

Query: 349 CVGTVESG 326
            + T + G
Sbjct: 348 SIKTPDLG 355
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>LEU3_LISMO (Q8Y5R8) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 350

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 32/151 (21%), Positives = 62/151 (41%), Gaps = 1/151 (0%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530
           I  EH  ID      ++    + V   +N  GD+ SD  +   GSLG++ S     +G +
Sbjct: 209 ITLEHLYIDAAAMLMIQRPTTFDVIVTENLFGDILSDEASVITGSLGMLPSASHAENGPS 268

Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
           +           +  +H    + +  +IA+  +    ++    L  +  L + A  ++ A
Sbjct: 269 L-----------YEPIHGSAPDIANQNIANPMSMISSVS--MMLRQSFSLFKEADAIDAA 315

Query: 349 CVGTVESGKMTKDLALLVHGSSKVTRSDYLN 257
              T+++G +T DL          T +D+ N
Sbjct: 316 ATRTMQAGFLTADL------GGNTTTTDFTN 340
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>LEU3_LISMF (Q71Y34) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 350

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 29/134 (21%), Positives = 57/134 (42%), Gaps = 1/134 (0%)
 Frame = -2

Query: 706 IWYEHRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKT 530
           I  EH  +D      ++    + V   +N  GD+ SD  +   GSLG++ S     +G +
Sbjct: 209 ITLEHLYVDAAAMLMIQRPTTFDVIVTENLFGDILSDEASVITGSLGMLPSASHAENGPS 268

Query: 529 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEA 350
           +           +  +H    + +  +IA+  +    ++    L  +  L E A  ++ A
Sbjct: 269 L-----------YEPIHGSAPDIANQNIANPMSMISSVS--MMLRQSFSLFEEADAIDAA 315

Query: 349 CVGTVESGKMTKDL 308
              T+++G +T DL
Sbjct: 316 TARTMQAGFLTADL 329
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>LEU3_AZOVI (P96197) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 360

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 39/157 (24%), Positives = 66/157 (42%), Gaps = 1/157 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  +D+     +++   + V    N  GD+ SD  +   GS+G++ S  +  D K +  E
Sbjct: 219 HMYVDNAAMQLVRAPKQFDVIVTDNMFGDILSDEASMLTGSIGMLPSASLDADNKGM-YE 277

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
             HG+     R     G+   N +A+I + +  L +      +   +E A  +E+A    
Sbjct: 278 PCHGS-----RRPDIAGKGIANPLATILSVSMMLRY------SFGQVEAANAIEQAVSKV 326

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVAA 227
           ++ G  T D  +   G  KV       T E  DAV A
Sbjct: 327 LDQGLRTGD--IWSEGCRKV------GTAEMGDAVVA 355
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>SYNJ1_BOVIN (O18964) Synaptojanin-1 (EC 3.1.3.36) (Synaptic|
           inositol-1,4,5-trisphosphate 5-phosphatase 1) (p150)
           (Fragment)
          Length = 1324

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 12/88 (13%)
 Frame = -2

Query: 502 VTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLE-------FAQKLEEA-- 350
           VTR   V +     + +SI+ I+A T  L  +AKL D AR +        F    +EA  
Sbjct: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVSRTIQNNFFDSSKQEAID 477

Query: 349 ---CVGTVESGKMTKDLALLVHGSSKVT 275
                 T+ S    K  ALL  GS +V+
Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVS 505
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>LEU3_BUCAI (P56933) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 363

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 35/155 (22%), Positives = 63/155 (40%), Gaps = 1/155 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +K    + V  C N  GD+ SD  A   GS+G++ S         +  E
Sbjct: 223 HLYIDNAAMQIIKDPNQFDVLLCSNLFGDIISDECATITGSIGMLPSASFNEKNFGL-YE 281

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +   L+      + A K+++A    
Sbjct: 282 PAGGSAP------DIEGKNIANPIAQILSLSMLVRYGMNLN------QIADKIDKAVNNV 329

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAV 233
           ++ G  T D++           +++L T+E  D +
Sbjct: 330 LKKGYRTSDIS---------HDNNFLKTDEMGDLI 355
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>LEU3_STAAR (Q6GF15) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 348

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 1/130 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H L+D    + + +   + V   +N  GD+ SD  +   GSLGL  S     DG  +   
Sbjct: 213 HLLVDACSMHLITNPKQFDVIVYENLFGDILSDEASVIPGSLGLSPSASFSNDGPRL--- 269

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
                   +  +H    + +  ++A+ F     LA    L ++    + A +LE+     
Sbjct: 270 --------YEPIHGSAPDIAGKNVANPFGMILSLA--MCLRESLNQPDAADELEQHIYNM 319

Query: 337 VESGKMTKDL 308
           +E G+ T DL
Sbjct: 320 IEHGQTTADL 329
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>LEU3_BUCML (Q9EVG3) 3-isopropylmalate dehydrogenase (EC 1.1.1.85) (Beta-IPM|
           dehydrogenase) (IMDH) (3-IPM-DH)
          Length = 365

 Score = 29.6 bits (65), Expect = 10.0
 Identities = 33/156 (21%), Positives = 64/156 (41%), Gaps = 1/156 (0%)
 Frame = -2

Query: 694 HRLIDDMVAYALKSEGGY-VWACKNYDGDVQSDFLAQGFGSLGLMTSVLMCPDGKTIEAE 518
           H  ID+     +++   + +  C N  GD+ SD  A   GS+G++ S  +      +  E
Sbjct: 224 HLYIDNATMQIIQNPNQFDILLCSNLFGDILSDECAIITGSIGMLPSASLNEKNFGL-YE 282

Query: 517 AAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLEFAQKLEEACVGT 338
            A G+           G+   N IA I + +  + +         L + A K++++ +  
Sbjct: 283 PAGGSAP------DIAGKNIANPIAQILSLSMLVRY------GMNLKKIANKIDQSVISV 330

Query: 337 VESGKMTKDLALLVHGSSKVTRSDYLNTEEFIDAVA 230
           ++ G  T D++           + +L T E  D +A
Sbjct: 331 LKKGYRTFDIS--------DDNNXFLKTNEMGDVIA 358


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,853,132
Number of Sequences: 219361
Number of extensions: 1827256
Number of successful extensions: 5080
Number of sequences better than 10.0: 165
Number of HSP's better than 10.0 without gapping: 4902
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5048
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7536258401
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
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