ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal29f10 |
|---|---|
| Clone Library Name | barley_pub |
>MRP14_ARATH (Q9LYS2) Multidrug resistance-associated protein 14 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 14) (ATP-energized glutathione S-conjugate pump 14) Length = 1389 Score = 212 bits (539), Expect = 8e-55 Identities = 104/135 (77%), Positives = 117/135 (86%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L KCQL E VQEKE GLDS VVEDGSNWSMGQRQLFCLGRA+LRR R+LVLDEATASIDN Sbjct: 1253 LGKCQLKEVVQEKENGLDSLVVEDGSNWSMGQRQLFCLGRAVLRRSRVLVLDEATASIDN 1312 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ATD +LQKTIR EF CTVITVAHRIPTVMDC MVL++SDG++VEYD+P KLM+ E SLF Sbjct: 1313 ATDLILQKTIRREFADCTVITVAHRIPTVMDCTMVLSISDGRIVEYDEPMKLMKDENSLF 1372 Query: 254 HKLVNEYWSYTSNGN 210 KLV EYWS+ ++ + Sbjct: 1373 GKLVKEYWSHYNSAD 1387 Score = 51.2 bits (121), Expect = 2e-06 Identities = 36/128 (28%), Positives = 63/128 (49%), Gaps = 1/128 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 + K L + ++ G + + E G N S GQ+Q L RAL + I +LD+ +++D Sbjct: 636 IQKSSLDKDLELLPDGDQTEIGERGVNLSGGQKQRIQLARALYQDADIYLLDDPFSAVDA 695 Query: 437 NATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 + ++ Q+ + V+ V H++ + D VL MSDG++ E D +L+ Sbjct: 696 HTASSLFQEYVMDALAGKAVLLVTHQVDFLPAFDSVLLMSDGEITEADTYQELLARSRD- 754 Query: 257 FHKLVNEY 234 F LVN + Sbjct: 755 FQDLVNAH 762
>MRP3_ARATH (Q9LK64) Multidrug resistance-associated protein 3 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 3) (ATP-energized glutathione S-conjugate pump 3) Length = 1514 Score = 167 bits (423), Expect = 2e-41 Identities = 83/133 (62%), Positives = 104/133 (78%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LDKCQL + V++KEQ LDS V E+G NWSMGQRQL CLGR LL+R +ILVLDEATAS+D Sbjct: 1379 LDKCQLGDEVRKKEQKLDSSVSENGDNWSMGQRQLVCLGRVLLKRSKILVLDEATASVDT 1438 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ATD ++QKT+R F CTVIT+AHRI +V+D DMVL +S+G + EYD P +L+E + S F Sbjct: 1439 ATDNLIQKTLREHFSDCTVITIAHRISSVIDSDMVLLLSNGIIEEYDTPVRLLEDKSSSF 1498 Query: 254 HKLVNEYWSYTSN 216 KLV EY S +S+ Sbjct: 1499 SKLVAEYTSRSSS 1511 Score = 47.0 bits (110), Expect = 4e-05 Identities = 34/129 (26%), Positives = 66/129 (51%), Gaps = 2/129 (1%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ C L + ++ G + + E G N S GQ+Q + RAL + I + D+ +++D Sbjct: 738 LEACSLSKDLEILSFGDQTVIGERGINLSGGQKQRIQIARALYQDADIYLFDDPFSAVDA 797 Query: 434 ATDAVLQKTIRSEFKYC--TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 T + L K + C +VI V H++ + D++L M DG++ + K ++ + G+ Sbjct: 798 HTGSHLFKEVLLGL-LCSKSVIYVTHQVEFLPAADLILVMKDGRISQAGKYNDILNS-GT 855 Query: 260 LFHKLVNEY 234 F +L+ + Sbjct: 856 DFMELIGAH 864
>MRP6_ARATH (Q8LGU1) Multidrug resistance-associated protein 6 precursor (EC| 3.6.3.44) (Glutathione S-conjugate transporting ATPase 6) (ATP-energized glutathione S-conjugate pump 6) Length = 1295 Score = 164 bits (415), Expect = 2e-40 Identities = 86/143 (60%), Positives = 109/143 (76%), Gaps = 1/143 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVED-GSNWSMGQRQLFCLGRALLRRCRILVLDEATASID 438 L+KCQL + LDS V D G NWS+GQRQLFCLGR LL+R +ILVLDEATASID Sbjct: 1155 LEKCQLKTTISNLPNKLDSSEVSDEGENWSVGQRQLFCLGRVLLKRNKILVLDEATASID 1214 Query: 437 NATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 +ATDA++Q+ IR EF CTVITVAHR+PTV+D DMV+ +S G +VEY++P+KLMET+ S Sbjct: 1215 SATDAIIQRIIREEFADCTVITVAHRVPTVIDSDMVMVLSFGDLVEYNEPSKLMETD-SY 1273 Query: 257 FHKLVNEYWSYTSNGNI*KSLSI 189 F KLV EYW+ + GN ++L + Sbjct: 1274 FSKLVAEYWA-SCRGNSSQNLQL 1295 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Frame = -2 Query: 560 SHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL-QKTIRSEFKYC 384 + + + G N S GQ+Q L RA+ + +LD+ +++D T VL K + K Sbjct: 555 TEIGQRGINLSGGQKQRIQLARAVYADADVYLLDDPFSAVDAHTAGVLFHKCVEDSLKEK 614 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 TVI V H++ M +G + + K +L+ G+ F +LVN + Sbjct: 615 TVILVTHQV-----------MEEGTITQSGKYEELL-MMGTAFQQLVNAH 652
>MRP15_ARATH (Q7FB56) Putative multidrug resistance-associated protein 15 (EC| 3.6.3.44) (Glutathione S-conjugate transporting ATPase 15) (ATP-energized glutathione S-conjugate pump 15) Length = 1037 Score = 161 bits (408), Expect = 1e-39 Identities = 75/127 (59%), Positives = 100/127 (78%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LDKCQL + ++ K++ LD+ VVE+G NWS+GQRQL CLGR LL++ ILVLDEATAS+D+ Sbjct: 896 LDKCQLGDVIRAKDEKLDATVVENGENWSVGQRQLVCLGRVLLKKSNILVLDEATASVDS 955 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ATD V+QK I EFK TV+T+AHRI TV++ D+VL +SDG++ E+D P KL++ E S F Sbjct: 956 ATDGVIQKIINQEFKDRTVVTIAHRIHTVIESDLVLVLSDGRIAEFDSPAKLLQREDSFF 1015 Query: 254 HKLVNEY 234 KL+ EY Sbjct: 1016 SKLIKEY 1022 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/112 (26%), Positives = 59/112 (52%), Gaps = 1/112 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 C L++ + G + + E G N S GQ+Q + RA+ + I +LD+ +++D T Sbjct: 315 CALIKDFELFSNGDLTEIGERGINMSGGQKQRIQIARAVYQNADIYLLDDPFSAVDAHTG 374 Query: 425 AVL-QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLME 273 L + + K TV+ V H++ + D++L M +G+V++ K +L++ Sbjct: 375 RELFEDCLMGILKDKTVLYVTHQVEFLPAADLILVMQNGRVMQAGKFEELLK 426
>MRP5_ARATH (Q7GB25) Multidrug resistance-associated protein 5 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 5) (ATP-energized glutathione S-conjugate pump 5) Length = 1514 Score = 160 bits (406), Expect = 2e-39 Identities = 79/129 (61%), Positives = 103/129 (79%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LDK QL + V+ K+ LDS V+E+G NWS+GQRQL LGRALL++ +ILVLDEATAS+D Sbjct: 1378 LDKSQLGDVVRGKDLKLDSPVLENGDNWSVGQRQLVSLGRALLKQAKILVLDEATASVDT 1437 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ATD ++QK IR+EF+ CTV T+AHRIPTV+D D+VL +SDG+V E+D P +L+E + S+F Sbjct: 1438 ATDNLIQKIIRTEFEDCTVCTIAHRIPTVIDSDLVLVLSDGRVAEFDTPARLLEDKSSMF 1497 Query: 254 HKLVNEYWS 228 KLV EY S Sbjct: 1498 LKLVTEYSS 1506 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 1/128 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 + C L + ++ G + + E G N S GQ+Q L RAL + I +LD+ +++D Sbjct: 720 IQACSLKKDIELFSHGDQTIIGERGINLSGGQKQRVQLARALYQDADIYLLDDPFSALDA 779 Query: 434 ATDA-VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T + + + I S TV+ V H++ + D++L + +G++++ K L++ G+ Sbjct: 780 HTGSDLFRDYILSALAEKTVVFVTHQVEFLPAADLILVLKEGRIIQSGKYDDLLQA-GTD 838 Query: 257 FHKLVNEY 234 F LV+ + Sbjct: 839 FKALVSAH 846
>MRP9_ARATH (Q9M1C7) Multidrug resistance-associated protein 9 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 9) (ATP-energized glutathione S-conjugate pump 9) Length = 1490 Score = 160 bits (406), Expect = 2e-39 Identities = 74/127 (58%), Positives = 100/127 (78%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 +DKCQL + ++ K++ LD+ VVE+G NWS+GQRQL CLGR LL++ ILVLDEATAS+D+ Sbjct: 1349 IDKCQLGDVIRAKDERLDATVVENGENWSVGQRQLVCLGRVLLKKSNILVLDEATASVDS 1408 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ATD V+QK I EFK TV+T+AHRI TV++ D+VL +SDG++ E+D P KL++ E S F Sbjct: 1409 ATDGVIQKIINQEFKDRTVVTIAHRIHTVIESDLVLVLSDGRIAEFDSPAKLLQREDSFF 1468 Query: 254 HKLVNEY 234 KL+ EY Sbjct: 1469 SKLIKEY 1475 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/112 (26%), Positives = 59/112 (52%), Gaps = 1/112 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 C L++ + G + + E G N S GQ+Q + RA+ + I +LD+ +++D T Sbjct: 731 CALIKDFELFSNGDLTEIGERGINMSGGQKQRIQIARAVYQNADIYLLDDPFSAVDAHTG 790 Query: 425 AVL-QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLME 273 L + + K TV+ V H++ + D++L M +G+V++ K +L++ Sbjct: 791 RELFEDCLMGILKDKTVLYVTHQVEFLPAADLILVMQNGRVMQAGKFEELLK 842
>MRP10_ARATH (Q9LZJ5) Multidrug resistance-associated protein 10 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 10) (ATP-energized glutathione S-conjugate pump 10) Length = 1539 Score = 156 bits (395), Expect = 4e-38 Identities = 75/127 (59%), Positives = 96/127 (75%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++CQL + V K + LDS V ++G NWS+GQRQL CLGR +L+R RIL LDEATAS+D+ Sbjct: 1407 LERCQLKDVVASKPEKLDSLVADNGENWSVGQRQLLCLGRVMLKRSRILFLDEATASVDS 1466 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TDA++QK IR +F CT+I++AHRIPTVMDCD VL + GK EYD P +L+E + SLF Sbjct: 1467 QTDAMIQKIIREDFSDCTIISIAHRIPTVMDCDRVLVIDAGKAKEYDSPVRLLERQ-SLF 1525 Query: 254 HKLVNEY 234 LV EY Sbjct: 1526 AALVQEY 1532 Score = 58.5 bits (140), Expect = 1e-08 Identities = 38/125 (30%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L C L + +Q E G + + E G N S GQ+Q L RA+ + + +LD+ +++D Sbjct: 737 LKVCCLEKDMQIMEFGDQTEIGERGINLSGGQKQRIQLARAVYQESDVYLLDDVFSAVDA 796 Query: 434 ATDA-VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T + + +K +R K T++ V H++ + + D +L M DG +V+ K +L+ + G Sbjct: 797 HTGSDIFKKCVRGALKGKTILLVTHQVDFLHNVDRILVMRDGMIVQSGKYDELV-SSGLD 855 Query: 257 FHKLV 243 F +LV Sbjct: 856 FGELV 860
>MRP7_ARATH (Q9LK62) Multidrug resistance-associated protein 7 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 7) (ATP-energized glutathione S-conjugate pump 7) Length = 1493 Score = 155 bits (392), Expect = 9e-38 Identities = 73/127 (57%), Positives = 97/127 (76%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LDKCQL + +++KE LDS V E+G NWS+GQRQL CLGR LL+R ++L+LDEATAS+D Sbjct: 1351 LDKCQLGDEIRKKELKLDSPVSENGQNWSVGQRQLVCLGRVLLKRSKVLILDEATASVDT 1410 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ATD ++Q+T+R F CTVIT+AHRI +V+D DMVL + G + E+D P +L+E + S F Sbjct: 1411 ATDTLIQETLRQHFSGCTVITIAHRISSVIDSDMVLLLDQGLIEEHDSPARLLEDKSSSF 1470 Query: 254 HKLVNEY 234 KLV EY Sbjct: 1471 SKLVAEY 1477 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/131 (29%), Positives = 70/131 (53%), Gaps = 4/131 (3%) Frame = -2 Query: 614 LDKCQL---LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATAS 444 L+ C L LE ++Q + + E G N S GQ+Q + RAL + I + D+ ++ Sbjct: 722 LEACSLNKDLEVFPFRDQTV---IGERGINLSGGQKQRIQIARALYQDADIYLFDDPFSA 778 Query: 443 IDNATDAVLQKTIR-SEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETE 267 +D T + L K + + TVI V H++ + + D++L M DG++ + K +++E+ Sbjct: 779 VDAHTGSHLFKEVLLGLLRNKTVIYVTHQLEFLPEADLILVMKDGRITQAGKYNEILES- 837 Query: 266 GSLFHKLVNEY 234 G+ F +LV + Sbjct: 838 GTDFMELVGAH 848
>MRP8_ARATH (Q8VZZ4) Multidrug resistance-associated protein 8 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 8) (ATP-energized glutathione S-conjugate pump 8) Length = 1466 Score = 153 bits (386), Expect = 4e-37 Identities = 75/127 (59%), Positives = 95/127 (74%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LD CQL + V++KE LDS V E+G NWS+GQRQL CLGR LL+R ++LVLDEATASID Sbjct: 1329 LDNCQLGDEVRKKELKLDSPVSENGQNWSVGQRQLVCLGRVLLKRSKLLVLDEATASIDT 1388 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ATD ++Q+T+R F CTVIT+AHRI +V+D DMVL + G + E+D P +L+E SLF Sbjct: 1389 ATDNLIQETLRHHFADCTVITIAHRISSVIDSDMVLLLDQGLIKEHDSPARLLEDRSSLF 1448 Query: 254 HKLVNEY 234 K V EY Sbjct: 1449 SKFVAEY 1455 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/106 (30%), Positives = 60/106 (56%), Gaps = 1/106 (0%) Frame = -2 Query: 548 EDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIR-SEFKYCTVIT 372 E G N S GQ+Q + RAL + I + D+ +++D T + L K + ++ TVI Sbjct: 721 ERGINLSGGQKQRIQIARALYQDADIYLFDDPFSAVDAHTGSHLFKEVLLGLLRHKTVIY 780 Query: 371 VAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 V H++ + + D++L M DGK+ + K +++++ G+ F +LV + Sbjct: 781 VTHQVEFLPEADLILVMKDGKITQAGKYHEILDS-GTDFMELVGAH 825
>MRP4_ARATH (Q7DM58) Multidrug resistance-associated protein 4 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 4) (ATP-energized glutathione S-conjugate pump 4) Length = 1516 Score = 150 bits (380), Expect = 2e-36 Identities = 74/127 (58%), Positives = 95/127 (74%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++CQL + V K + LDS VV++G NWS+GQRQL CLGR +L+R R+L LDEATAS+D+ Sbjct: 1384 LERCQLKDVVATKPEKLDSLVVDNGENWSVGQRQLLCLGRVMLKRSRLLFLDEATASVDS 1443 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TDAV+QK IR +F CT+I++AHRIPTVMD D VL + GK E+D P +L+E SLF Sbjct: 1444 QTDAVIQKIIREDFASCTIISIAHRIPTVMDGDRVLVIDAGKAKEFDSPARLLE-RPSLF 1502 Query: 254 HKLVNEY 234 LV EY Sbjct: 1503 AALVQEY 1509 Score = 68.2 bits (165), Expect = 2e-11 Identities = 42/125 (33%), Positives = 71/125 (56%), Gaps = 1/125 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ C L + +Q E G + + E G N S GQ+Q L RA+ + C + +LD+ +++D Sbjct: 739 LNVCSLEKDLQMMEFGDKTEIGERGINLSGGQKQRIQLARAVYQECDVYLLDDVFSAVDA 798 Query: 434 ATDA-VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T + + +K +R K TV+ V H++ + + D +L M DGK+VE K +L+ + G Sbjct: 799 HTGSDIFKKCVRGALKGKTVLLVTHQVDFLHNVDCILVMRDGKIVESGKYDELV-SSGLD 857 Query: 257 FHKLV 243 F +LV Sbjct: 858 FGELV 862
>MRP2_ARATH (Q42093) Multidrug resistance-associated protein 2 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 2) (ATP-energized glutathione S-conjugate pump 2) Length = 1623 Score = 137 bits (344), Expect = 3e-32 Identities = 64/124 (51%), Positives = 89/124 (71%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ L + ++ GLD+ V E G N+S+GQRQL L RALLRR +ILVLDEATA++D Sbjct: 1352 LERAHLKDTIRRNPLGLDAEVSEAGENFSVGQRQLLSLSRALLRRSKILVLDEATAAVDV 1411 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TDA++QKTIR EFK CT++ +AHR+ T++DCD +L + G+V E+ P L+ EGS F Sbjct: 1412 RTDALIQKTIREEFKSCTMLIIAHRLNTIIDCDKILVLDSGRVQEFSSPENLLSNEGSSF 1471 Query: 254 HKLV 243 K+V Sbjct: 1472 SKMV 1475
>MRP12_ARATH (Q9C8H1) Multidrug resistance-associated protein 12 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 12) (ATP-energized glutathione S-conjugate pump 12) Length = 1495 Score = 136 bits (342), Expect = 6e-32 Identities = 66/137 (48%), Positives = 95/137 (69%), Gaps = 4/137 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ + + + GLD+ V E G N+S+GQRQL L RALLRR +IL LDEATAS+D Sbjct: 1345 LERAHIKDVIDRNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILFLDEATASVDV 1404 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD+++Q+TIR EFK CT++ +AHR+ T++DCD +L +S G+V+EYD P +L+ + S F Sbjct: 1405 RTDSLIQRTIREEFKSCTMLIIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAF 1464 Query: 254 HKLVN----EYWSYTSN 216 K+V+ E Y SN Sbjct: 1465 FKMVHSTGPENGQYLSN 1481
>MRP13_ARATH (Q9C8H0) Multidrug resistance-associated protein 13 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 13) (ATP-energized glutathione S-conjugate pump 13) Length = 1495 Score = 135 bits (341), Expect = 7e-32 Identities = 62/125 (49%), Positives = 91/125 (72%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L + + + + GLD+ V E G N+S+GQRQL L RALLRR +ILVLDEATAS+D Sbjct: 1345 LHRAHIKDVISRNPFGLDAEVCEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDV 1404 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD+++Q+TIR EFK CT++ +AHR+ T++DCD +L +S G+V+EYD P +L+ + S F Sbjct: 1405 RTDSLIQRTIREEFKSCTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAF 1464 Query: 254 HKLVN 240 ++V+ Sbjct: 1465 FRMVH 1469
>MRP1_ARATH (Q9C8G9) Multidrug resistance-associated protein 1 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 1) (ATP-energized glutathione S-conjugate pump 1) Length = 1622 Score = 133 bits (334), Expect = 5e-31 Identities = 66/142 (46%), Positives = 95/142 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ L + ++ GLD+ V E G N+S+GQRQL L RALLRR +ILVLDEATA++D Sbjct: 1347 LERAHLKDTIRRNPLGLDAEVTEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDV 1406 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++QKTIR EFK CT++ +AHR+ T++DCD VL + GKV E+ P L+ S F Sbjct: 1407 RTDVLIQKTIREEFKSCTMLIIAHRLNTIIDCDKVLVLDSGKVQEFSSPENLLSNGESSF 1466 Query: 254 HKLVNEYWSYTSNGNI*KSLSI 189 K+V + T+N +S+++ Sbjct: 1467 SKMVQS--TGTANAEYLRSITL 1486 Score = 42.7 bits (99), Expect = 8e-04 Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Frame = -2 Query: 560 SHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NATDAVLQKTIRSEFKYC 384 + + E G N S GQ+Q + RA+ + +LD+ +++D + V +K I+ E Sbjct: 731 TEIGERGVNISGGQKQRVSMARAVYSNSDVCILDDPLSALDAHVGQQVFEKCIKRELGQT 790 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T + V +++ + D +L + +G V E +L + G LF +L+ Sbjct: 791 TRVLVTNQLHFLSQVDKILLVHEGTVKEEGTYEELCHS-GPLFQRLM 836
>L259_DROME (P91660) Probable multidrug resistance-associated protein| lethal(2)03659 (Wunen region A protein) Length = 1290 Score = 132 bits (332), Expect = 8e-31 Identities = 64/127 (50%), Positives = 94/127 (74%), Gaps = 1/127 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ +L E V + GL S + E G+N+S+GQRQL CL RA+LR RILV+DEATA++D Sbjct: 1145 LEEVKLKEVVSDLPDGLASKISEGGTNFSVGQRQLVCLARAILRENRILVMDEATANVDP 1204 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLM-ETEGSL 258 TD ++Q TIRS+F+ CTV+T+AHR+ T++D D V+ M G+VVE+ P +LM +++ + Sbjct: 1205 QTDGLIQATIRSKFRDCTVLTIAHRLHTIIDSDKVMVMDAGRVVEFGSPYELMTKSDSKV 1264 Query: 257 FHKLVNE 237 FH LVN+ Sbjct: 1265 FHNLVNQ 1271 Score = 40.0 bits (92), Expect = 0.005 Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -2 Query: 554 VVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NATDAVLQKTIRSEFKYCTV 378 V E G+ S GQ+ L R++ R+ I +LD+ +++D + + + +R + TV Sbjct: 534 VGERGATLSGGQKARISLARSVYRKASIYLLDDPLSAVDASVARHLFDQCVRGHLRGSTV 593 Query: 377 ITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMET 270 + V H+ + D ++ +++G++ L++T Sbjct: 594 VLVTHQEQFLPHVDQIVILANGQIKALGDYESLLKT 629
>MRP4_HUMAN (O15439) Multidrug resistance-associated protein 4 (MRP/cMOAT-related| ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B) Length = 1325 Score = 131 bits (329), Expect = 2e-30 Identities = 57/126 (45%), Positives = 94/126 (74%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L + QL E +++ +D+ + E GSN+S+GQRQL CL RA+LR+ +IL++DEATA++D Sbjct: 1150 LQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDP 1209 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++QK IR +F +CTV+T+AHR+ T++D D ++ + G++ EYD+P L++ + SLF Sbjct: 1210 RTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLF 1269 Query: 254 HKLVNE 237 +K+V + Sbjct: 1270 YKMVQQ 1275 Score = 37.4 bits (85), Expect = 0.035 Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 4/123 (3%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 C L + +Q E G + + + G+ S GQ+ L RA+ + I +LD+ +++D Sbjct: 511 CALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVS 570 Query: 425 AVLQKTIRSEFKYCTV-ITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETE---GSL 258 L + + + + I V H++ + +L + DGK+V+ T+ +++ GSL Sbjct: 571 RHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSL 630 Query: 257 FHK 249 K Sbjct: 631 LKK 633
>YH85_SCHPO (Q9P5N0) Probable ATP-dependent permease C359.05| Length = 1465 Score = 129 bits (325), Expect = 5e-30 Identities = 66/126 (52%), Positives = 85/126 (67%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L + + E GL S V E G+N+S GQRQL CL R LL RIL+LDEATAS+ Sbjct: 1336 LEIASLKNCISQLEDGLYSRVAEGGANFSSGQRQLICLARVLLTSTRILLLDEATASVHA 1395 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TDA++Q+TIR FK T++TVAHRI TVMD D +L + GKVVE+D KL+E + S+F Sbjct: 1396 ETDAIVQQTIRKRFKDRTILTVAHRINTVMDSDRILVLDHGKVVEFDATKKLLENKDSMF 1455 Query: 254 HKLVNE 237 + L E Sbjct: 1456 YSLAKE 1461 Score = 41.2 bits (95), Expect = 0.002 Identities = 28/117 (23%), Positives = 56/117 (47%), Gaps = 4/117 (3%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSE- 396 +G + V + G++ S GQ+ L RA+ + I +LD+ +S+D L K + Sbjct: 691 EGDQTEVGQKGASLSGGQKSRISLARAIYSQADIYLLDDVLSSVDQHVSRDLIKNLFGPE 750 Query: 395 ---FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 +C V+T + + + + D + +S+GK+VE L + S + ++E+ Sbjct: 751 GFLRTHCVVLT-TNSLNVLKEADSIYILSNGKIVEKGNYEHLFVSTNSELKQQLSEF 806
>MRP2_RAT (Q63120) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein) Length = 1541 Score = 129 bits (325), Expect = 5e-30 Identities = 62/120 (51%), Positives = 84/120 (70%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L V + GL S V E G N S+GQRQL CLGRA+LR+ +ILVLDEATA++D Sbjct: 1406 LELAHLRSFVSGLQLGLLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDL 1465 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD+++Q TIR EF CTVIT+AHR+ T+MD D ++ + +GK+VEY P +L+ GS + Sbjct: 1466 ETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNRGSFY 1525 Score = 37.7 bits (86), Expect = 0.027 Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 3/120 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 L C LL ++ G + + E G N S GQ+Q L RA + I +LD+ +++D Sbjct: 730 LKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDA 789 Query: 437 NATDAVLQKTIRSEFKYC--TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + K + T I V H I + D ++ + G ++E L++ +G Sbjct: 790 HVGKHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKG 849
>ABCCB_HUMAN (Q96J66) ATP-binding cassette transporter sub-family C member 11| (Multidrug resistance-associated protein 8) Length = 1382 Score = 129 bits (324), Expect = 7e-30 Identities = 60/124 (48%), Positives = 92/124 (74%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ L +A+ + + L + VVE+G N+S+G+RQL C+ RA+LR +I+++DEATASID Sbjct: 1251 LERTFLTKAISKFPKKLHTDVVENGGNFSVGERQLLCIARAVLRNSKIILIDEATASIDM 1310 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q+TIR F+ CTV+ +AHR+ TV++CD +L M +GKVVE+D+P L + GSLF Sbjct: 1311 ETDTLIQRTIREAFQGCTVLVIAHRVTTVLNCDHILVMGNGKVVEFDRPEVLRKKPGSLF 1370 Query: 254 HKLV 243 L+ Sbjct: 1371 AALM 1374 Score = 49.7 bits (117), Expect = 7e-06 Identities = 29/115 (25%), Positives = 60/115 (52%), Gaps = 1/115 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NAT 429 C L ++ G + + E G N S GQ+Q L RA+ +I +LD+ +++D + Sbjct: 610 CSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQIYLLDDPLSAVDAHVG 669 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + ++ I+ + TV+ V H++ + C ++ + +GK+ E ++LM+ +G Sbjct: 670 KHIFEECIKKTLRGKTVVLVTHQLQYLEFCGQIILLENGKICENGTHSELMQKKG 724
>YAWB_SCHPO (Q10185) Probable ATP-dependent permease C3F10.11c| Length = 1478 Score = 127 bits (318), Expect = 3e-29 Identities = 64/126 (50%), Positives = 86/126 (68%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L + +Q + GL S V E G+N S GQRQL CL RALL R+L+LDEATA++D Sbjct: 1349 LEAASLKQFIQTLDGGLYSRVTEGGANLSSGQRQLMCLTRALLTPTRVLLLDEATAAVDV 1408 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TDA++Q+TIR F T++T+AHRI TVMD + +L + GKVVE+D KL+E + SLF Sbjct: 1409 ETDAIVQRTIRERFNDRTILTIAHRINTVMDSNRILVLDHGKVVEFDSTKKLLENKASLF 1468 Query: 254 HKLVNE 237 + L E Sbjct: 1469 YSLAKE 1474 Score = 44.7 bits (104), Expect = 2e-04 Identities = 30/127 (23%), Positives = 60/127 (47%), Gaps = 3/127 (2%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 C LL + G + V E G + S GQ+ L RA+ R I +LD+ +++D + Sbjct: 697 CCLLRDFEILADGDQTEVGEKGISLSGGQKARISLARAVYSRSDIYLLDDILSAVDQHVN 756 Query: 425 AVLQKTI---RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 L + + + + VI + + + + M+ + +GK++E T+L + S Sbjct: 757 RDLVRNLLGSKGLLRSRCVILSTNSLTVLKEASMIYMLRNGKIIESGSFTQLSSSPDSQL 816 Query: 254 HKLVNEY 234 +L++E+ Sbjct: 817 FQLLSEF 823
>MRP2_MOUSE (Q8VI47) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) Length = 1543 Score = 124 bits (312), Expect = 2e-28 Identities = 60/120 (50%), Positives = 82/120 (68%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L V + GL V E G N S+GQRQL CLGRA+LR+ +ILVLDEATA++D Sbjct: 1408 LELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDL 1467 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD+++Q TIR+EF CTVIT+AHR+ T+MD D ++ + GK+VEY P +L+ G + Sbjct: 1468 ETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNMGPFY 1527 Score = 38.9 bits (89), Expect = 0.012 Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 3/120 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 ++ C LL ++ G + + E G N S GQ+ L RA + I +LD+ +++D Sbjct: 732 IEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDT 791 Query: 437 NATDAVLQKTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + K + T I V H I + D ++ + G ++E + LM+ +G Sbjct: 792 HVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKG 851
>MRP2_RABIT (Q28689) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein) (Epithelial basolateral chloride conductance reg Length = 1564 Score = 124 bits (311), Expect = 2e-28 Identities = 60/117 (51%), Positives = 82/117 (70%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L V + GL V E N S+GQRQL CLGRALLR+ +ILVLDEATA++D Sbjct: 1408 LELAHLKSFVAGLQHGLSREVSEAEDNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDL 1467 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 TD ++Q TIR+EF +CTVIT+AHR+ T+MD D ++ + +G +VEY P +L+E+ G Sbjct: 1468 ETDHLIQTTIRNEFSHCTVITIAHRLHTIMDSDKIMVLDNGNIVEYGSPEELLESAG 1524 Score = 38.9 bits (89), Expect = 0.012 Identities = 31/136 (22%), Positives = 63/136 (46%), Gaps = 3/136 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 L+ C LL ++ G + + E G N S GQ+Q L RA + I +LD+ +++D Sbjct: 732 LEACALLPDLEILPGGDLAEIGEKGINLSGGQKQRISLARASYQNSDIYILDDPLSAVDA 791 Query: 437 NATDAVLQKTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + K + T + V H + + D ++ + +G ++E + L+ +G Sbjct: 792 HVGKHIFNKVLGPNGLLNGKTRLLVTHSLHFLPQVDEIVVVENGTILEKGSYSSLLAKKG 851 Query: 263 SLFHKLVNEYWSYTSN 216 +F K + + +T + Sbjct: 852 -VFAKNLKMFVKHTDS 866
>MRP5_HUMAN (O15440) Multidrug resistance-associated protein 5 (Multi-specific| organic anion transporter-C) (MOAT-C) (pABC11) (SMRP) Length = 1437 Score = 124 bits (311), Expect = 2e-28 Identities = 54/123 (43%), Positives = 89/123 (72%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ + E + + L+S V+E+G N+S+G+RQL C+ RALLR C+IL+LDEATA++D Sbjct: 1303 LERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDT 1362 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q+TIR F CT++T+AHR+ TV+ D ++ ++ G+VVE+D P+ L+ + S F Sbjct: 1363 ETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRF 1422 Query: 254 HKL 246 + + Sbjct: 1423 YAM 1425 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 4/110 (3%) Frame = -2 Query: 560 SHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NATDAVLQKTIRSEFKYC 384 + + E G+N S GQRQ L RAL I +LD+ +++D + + + IR K Sbjct: 676 TEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSK 735 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG---SLFHKLV 243 TV+ V H++ ++DCD V+ M +G + E +LM G ++F+ L+ Sbjct: 736 TVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLL 785
>MRP5_RAT (Q9QYM0) Multidrug resistance-associated protein 5| Length = 1436 Score = 124 bits (311), Expect = 2e-28 Identities = 54/123 (43%), Positives = 89/123 (72%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ + E + + L+S V+E+G N+S+G+RQL C+ RALLR C+IL+LDEATA++D Sbjct: 1302 LERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDT 1361 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q+TIR F CT++T+AHR+ TV+ D ++ ++ G+VVE+D P+ L+ + S F Sbjct: 1362 ETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRF 1421 Query: 254 HKL 246 + + Sbjct: 1422 YAM 1424 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 4/110 (3%) Frame = -2 Query: 560 SHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NATDAVLQKTIRSEFKYC 384 + + E G+N S GQRQ L RAL I +LD+ +++D + + + IR K Sbjct: 676 TEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKRLKSK 735 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG---SLFHKLV 243 TV+ V H++ ++DCD V+ M +G + E +LM G ++F+ L+ Sbjct: 736 TVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLL 785
>MRP5_MOUSE (Q9R1X5) Multidrug resistance-associated protein 5 (ABC transporter| MOAT-C) (SMRP) Length = 1436 Score = 124 bits (311), Expect = 2e-28 Identities = 54/123 (43%), Positives = 89/123 (72%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ + E + + L+S V+E+G N+S+G+RQL C+ RALLR C+IL+LDEATA++D Sbjct: 1302 LERTHMKECIAQLPLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDT 1361 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q+TIR F CT++T+AHR+ TV+ D ++ ++ G+VVE+D P+ L+ + S F Sbjct: 1362 ETDLLIQETIREAFADCTMLTIAHRLHTVLGSDRIMVLAQGQVVEFDTPSVLLSNDSSRF 1421 Query: 254 HKL 246 + + Sbjct: 1422 YAM 1424 Score = 58.5 bits (140), Expect = 1e-08 Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 4/110 (3%) Frame = -2 Query: 560 SHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NATDAVLQKTIRSEFKYC 384 + + E G+N S GQRQ L RAL I +LD+ +++D + + + IR K Sbjct: 676 TEIGERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKRLKSK 735 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG---SLFHKLV 243 TV+ V H++ ++DCD V+ M +G + E +LM G ++F+ L+ Sbjct: 736 TVLFVTHQLQYLVDCDEVIFMKEGCITERGTHEELMNLNGDYATIFNNLL 785
>MRP2_HUMAN (Q92887) Canalicular multispecific organic anion transporter 1| (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein) Length = 1545 Score = 123 bits (309), Expect = 4e-28 Identities = 59/120 (49%), Positives = 83/120 (69%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L V + GL V E G N S+GQRQL CLGRALLR+ +ILVLDEATA++D Sbjct: 1410 LELAHLKSFVASLQLGLSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDL 1469 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q TI++EF +CTVIT+AHR+ T+MD D V+ + +GK++E P +L++ G + Sbjct: 1470 ETDNLIQTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELLQIPGPFY 1529 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 3/126 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 L+ C LL ++ G + + E G N S GQ+Q L RA + I +LD+ +++D Sbjct: 734 LEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDA 793 Query: 437 NATDAVLQKTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + K + K T + V H + + D ++ + +G +VE + L+ +G Sbjct: 794 HVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKG 853 Query: 263 SLFHKL 246 L Sbjct: 854 EFAKNL 859
>BPT1_YEAST (P14772) Bile pigment transporter 1| Length = 1559 Score = 122 bits (307), Expect = 6e-28 Identities = 59/107 (55%), Positives = 79/107 (73%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 LD + E+GSN S+GQRQL CL RALL R +ILVLDEATAS+D TD ++Q TIR EFK Sbjct: 1445 LDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTIRREFKD 1504 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 T++T+AHRI TV+D D ++ + G V E+D P+KL+ + S+F+ L Sbjct: 1505 RTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSL 1551 Score = 48.5 bits (114), Expect = 2e-05 Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 10/142 (7%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQLL ++ G ++ V E G + S GQ+ L RA+ R I +LD+ I +A D Sbjct: 746 CQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDD----ILSAVD 801 Query: 425 AVLQKTI--------RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMET 270 A + K I + K T+I + + + M+ A+ +G++VE +M Sbjct: 802 AEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYEDVMNR 861 Query: 269 EG--SLFHKLVNEYWSYTSNGN 210 + S KL+ E+ S NGN Sbjct: 862 KNNTSKLKKLLEEFDSPIDNGN 883
>YCFI_YEAST (P39109) Metal resistance protein YCF1 (Yeast cadmium factor 1)| Length = 1515 Score = 119 bits (298), Expect = 7e-27 Identities = 57/111 (51%), Positives = 80/111 (72%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 GLD+ + E G N S+GQRQL CL RA+L +ILVLDEATA++D TD V+Q+TIR+ FK Sbjct: 1398 GLDAQLTEGGGNLSVGQRQLLCLARAMLVPSKILVLDEATAAVDVETDKVVQETIRTAFK 1457 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 T++T+AHR+ T+MD D ++ + +GKV E+D P +L+ SLF+ L E Sbjct: 1458 DRTILTIAHRLNTIMDSDRIIVLDNGKVAEFDSPGQLLSDNKSLFYSLCME 1508 Score = 32.0 bits (71), Expect = 1.5 Identities = 23/110 (20%), Positives = 47/110 (42%), Gaps = 3/110 (2%) Frame = -2 Query: 554 VVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTI---RSEFKYC 384 V E G + S GQ+ L RA+ R +LD+ A++D L + + Sbjct: 746 VGEKGISLSGGQKARLSLARAVYARADTYLLDDPLAAVDEHVARHLIEHVLGPNGLLHTK 805 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 T + +++ + D + + +G++ + ++ + S KL+N Y Sbjct: 806 TKVLATNKVSALSIADSIALLDNGEITQQGTYDEITKDADSPLWKLLNNY 855
>ABCC8_HUMAN (Q09428) ATP-binding cassette transporter sub-family C member 8| (Sulfonylurea receptor 1) Length = 1580 Score = 117 bits (294), Expect = 2e-26 Identities = 56/124 (45%), Positives = 83/124 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V+ GLD+ + E G N+S GQRQLFCL RA +R+ I ++DEATASID Sbjct: 1453 LEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDM 1512 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 AT+ +LQK + + F TV+T+AHR+ T++ D+V+ + G ++E+DKP KL+ + S+F Sbjct: 1513 ATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVF 1572 Query: 254 HKLV 243 V Sbjct: 1573 ASFV 1576 Score = 50.4 bits (119), Expect = 4e-06 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 3/136 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 ++ C L + G + + E G N S GQRQ + RAL + ++ LD+ +++D Sbjct: 801 IEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDI 860 Query: 437 NATDAVLQKTIRSEFK--YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + +D ++Q I + TV+ V H++ + D ++AM DG + +E Sbjct: 861 HLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSEC 920 Query: 263 SLFHKLVNEYWSYTSN 216 LF E+W N Sbjct: 921 QLF-----EHWKTLMN 931
>ABCC8_RAT (Q09429) ATP-binding cassette transporter sub-family C member 8| (Sulfonylurea receptor 1) Length = 1581 Score = 117 bits (294), Expect = 2e-26 Identities = 56/124 (45%), Positives = 83/124 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V+ GLD+ + E G N+S GQRQLFCL RA +R+ I ++DEATASID Sbjct: 1454 LEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDM 1513 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 AT+ +LQK + + F TV+T+AHR+ T++ D+V+ + G ++E+DKP KL+ + S+F Sbjct: 1514 ATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVF 1573 Query: 254 HKLV 243 V Sbjct: 1574 ASFV 1577 Score = 50.1 bits (118), Expect = 5e-06 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 3/136 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 ++ C L + G + + E G N S GQRQ + RAL + ++ LD+ +++D Sbjct: 802 IEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHTNVVFLDDPFSALDV 861 Query: 437 NATDAVLQKTIRSEFK--YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + +D ++Q I + TV+ V H++ + D ++AM DG + +E Sbjct: 862 HLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSEC 921 Query: 263 SLFHKLVNEYWSYTSN 216 LF E+W N Sbjct: 922 QLF-----EHWKTLMN 932
>MRP3_RAT (O88563) Canalicular multispecific organic anion transporter 2| (Multidrug resistance-associated protein 3) (MRP-like protein 2) (MLP-2) Length = 1522 Score = 117 bits (292), Expect = 3e-26 Identities = 60/126 (47%), Positives = 83/126 (65%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L V + GLD E G N S+GQRQL CL RALLR+ R+LVLDEATA+ID Sbjct: 1394 LELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDL 1453 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q TIR++F+ CTV+T+AHR+ T+MD + VL + G V E+D P L+ G +F Sbjct: 1454 ETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLI-AAGGIF 1512 Query: 254 HKLVNE 237 + + + Sbjct: 1513 YGMAKD 1518 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 3/128 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 L+ C LL + G + + E G N S GQRQ L RA+ I +LD+ +++D Sbjct: 722 LETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDS 781 Query: 437 NATDAVLQKTIRSEFKYC--TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + + I E T + V H I + D ++ ++DG++ E ++L++ +G Sbjct: 782 HVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDG 841 Query: 263 SLFHKLVN 240 S + L N Sbjct: 842 SFANFLRN 849
>MRP3_HUMAN (O15438) Canalicular multispecific organic anion transporter 2| (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D) Length = 1527 Score = 116 bits (291), Expect = 5e-26 Identities = 60/120 (50%), Positives = 77/120 (64%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L V + GLD E G N S+GQRQL CL RALLR+ RILVLDEATA+ID Sbjct: 1399 LELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDL 1458 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q TIR++F CTV+T+AHR+ T+MD VL + G V E+D P L+ G + Sbjct: 1459 ETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAARGIFY 1518 Score = 49.7 bits (117), Expect = 7e-06 Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 3/128 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 L+ C LL ++ G + + E G N S GQRQ L RA+ I +LD+ +++D Sbjct: 724 LEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDS 783 Query: 437 NATDAVLQKTIRSEFKYC--TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + I E T + V H I + D ++ ++DG+V E L++ G Sbjct: 784 HVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNG 843 Query: 263 SLFHKLVN 240 S + L N Sbjct: 844 SFANFLCN 851
>ABCC9_RABIT (P82451) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1549 Score = 116 bits (290), Expect = 6e-26 Identities = 59/124 (47%), Positives = 83/124 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V+ GLD+ V E G N+S+GQRQLFCL RA +R+ IL++DEATASID Sbjct: 1422 LEIAQLKNMVKSLSGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDM 1481 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 AT+ +LQK + + F TV+T+AHR+ +++D D+VL S+G +VE D L+ + LF Sbjct: 1482 ATENILQKVVMTAFADRTVVTIAHRVSSIVDADLVLVFSEGILVECDTGPNLLTHKNGLF 1541 Query: 254 HKLV 243 LV Sbjct: 1542 STLV 1545 Score = 49.3 bits (116), Expect = 9e-06 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 3/135 (2%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-N 435 D C L + G + + E G N S GQ + C+ RAL + I+ LD+ +++D + Sbjct: 786 DACSLQPDIDLLPFGDQTEIGERGINLSGGQTERICVARALYQNTNIVFLDDPFSALDIH 845 Query: 434 ATDAVLQKTIRS--EFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 +D ++Q+ I + T++ V H++ + D ++AM DG V+ + + Sbjct: 846 LSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVE 905 Query: 260 LFHKLVNEYWSYTSN 216 L+ E+W N Sbjct: 906 LY-----EHWKTLMN 915
>ABCC9_RAT (Q63563) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1545 Score = 116 bits (290), Expect = 6e-26 Identities = 59/124 (47%), Positives = 83/124 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V+ GLD+ V E G N+S+GQRQLFCL RA +R+ IL++DEATASID Sbjct: 1418 LEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDM 1477 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 AT+ +LQK + + F TV+T+AHR+ ++MD +VL S+G +VE D L++ + LF Sbjct: 1478 ATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTGPNLLQHKNGLF 1537 Query: 254 HKLV 243 LV Sbjct: 1538 STLV 1541 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 3/135 (2%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-N 435 D C L + G + + E G N S GQRQ C+ RAL + I+ LD+ +++D + Sbjct: 782 DACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 841 Query: 434 ATDAVLQKTIRS--EFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 +D ++Q+ I + TV+ V H++ + D ++AM DG V+ + + Sbjct: 842 LSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVE 901 Query: 260 LFHKLVNEYWSYTSN 216 L+ E+W N Sbjct: 902 LY-----EHWKTLMN 911
>MRP11_ARATH (Q9SKX0) Multidrug resistance-associated protein 11 (EC 3.6.3.44)| (Glutathione S-conjugate transporting ATPase 11) (ATP-energized glutathione S-conjugate pump 11) Length = 1194 Score = 115 bits (289), Expect = 8e-26 Identities = 64/124 (51%), Positives = 83/124 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LDKC++ AV E GLDS+V E G ++S+GQRQL CL RALL+ +IL LDE TA+ID Sbjct: 1068 LDKCKVKAAV-ESVGGLDSYVKESGCSFSVGQRQLLCLARALLKSSKILCLDECTANIDV 1126 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T ++L TI SE K TVIT+AHRI TV+D D +L + G +VE KP L++ + S F Sbjct: 1127 HTASLLHNTISSECKGVTVITIAHRISTVVDLDSILILDRGILVEQGKPQHLLQDDSSTF 1186 Query: 254 HKLV 243 V Sbjct: 1187 SSFV 1190 Score = 40.0 bits (92), Expect = 0.005 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 2/107 (1%) Frame = -2 Query: 548 EDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA-VLQKTIRSE-FKYCTVI 375 + G N S GQR F L RA+ + +LD+ +++D+ +LQ+ + T + Sbjct: 471 DKGLNLSGGQRARFALARAVYHGSDMYLLDDVLSAVDSQVGCWILQRALLGPLLNKKTRV 530 Query: 374 TVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 H I + DM++ M GKV T + ++ F L NE+ Sbjct: 531 MCTHNIQAISCADMIVVMDKGKVNWSGSVTDMPKSISPTF-SLTNEF 576
>ABCC8_CRICR (Q09427) ATP-binding cassette transporter sub-family C member 8| (Sulfonylurea receptor 1) Length = 1581 Score = 115 bits (288), Expect = 1e-25 Identities = 55/124 (44%), Positives = 82/124 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V+ GLD+ + E G N+S GQRQLFCL RA +R+ I ++DEATASID Sbjct: 1454 LEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDM 1513 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 AT+ +LQK + + F TV+T+AHR+ T++ D+V+ + G ++E+DKP L+ + S+F Sbjct: 1514 ATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPETLLSQKDSVF 1573 Query: 254 HKLV 243 V Sbjct: 1574 ASFV 1577 Score = 50.4 bits (119), Expect = 4e-06 Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 3/136 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 ++ C L + G + + E G N S GQRQ + RAL ++ ++ LD+ +++D Sbjct: 802 IEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQQTNVVFLDDPFSALDV 861 Query: 437 NATDAVLQKTIRSEFK--YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + +D ++Q I + TV+ V H++ + D ++AM DG + +E Sbjct: 862 HLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSEC 921 Query: 263 SLFHKLVNEYWSYTSN 216 LF E+W N Sbjct: 922 QLF-----EHWKTLMN 932
>MRP1_CHICK (Q5F364) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1525 Score = 115 bits (287), Expect = 1e-25 Identities = 59/126 (46%), Positives = 83/126 (65%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L V L+ E G N S+GQRQL CL RALLR+ +ILVLDEATA++D Sbjct: 1397 LELAHLKNFVSSLPDKLNHECSEGGENLSVGQRQLVCLARALLRKSKILVLDEATAAVDL 1456 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q TI+S+F+ CTV+T+AHR+ T+MD VL + G+VVE D P L++ +G LF Sbjct: 1457 ETDNLIQSTIKSQFEECTVLTIAHRLNTIMDYTRVLVLDRGEVVECDSPDNLLQAKG-LF 1515 Query: 254 HKLVNE 237 + + + Sbjct: 1516 YSMAKD 1521 Score = 46.2 bits (108), Expect = 8e-05 Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 3/121 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 ++ C LL ++ G + + E G N S GQ+Q L RA+ + D+ +++D Sbjct: 738 IEACALLPDLEILPMGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADTYLFDDPLSAVDA 797 Query: 437 NATDAVLQKTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + +K I + K T + V H + + D +L M+DG++ E +L++ +G Sbjct: 798 HVGKHIFEKVIGPKGILKNKTRVLVTHAVNYLPQMDTILVMTDGEISEMGSYQELLKQDG 857 Query: 263 S 261 + Sbjct: 858 A 858
>ABCC9_MOUSE (P70170) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1546 Score = 114 bits (286), Expect = 2e-25 Identities = 58/124 (46%), Positives = 83/124 (66%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V+ GLD+ V E G N+S+GQRQLFCL RA +R+ IL++DEATASID Sbjct: 1419 LEIAQLKNMVKSLPGGLDATVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDM 1478 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 AT+ +LQK + + F TV+T+AHR+ +++D +VL S+G +VE D L++ + LF Sbjct: 1479 ATENILQKVVMTAFADRTVVTIAHRVSSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLF 1538 Query: 254 HKLV 243 LV Sbjct: 1539 STLV 1542 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/135 (27%), Positives = 64/135 (47%), Gaps = 3/135 (2%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-N 435 D C L + G + + E G N S GQRQ C+ RAL + I+ LD+ +++D + Sbjct: 783 DACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 842 Query: 434 ATDAVLQKTIRS--EFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 +D ++Q+ I + TV+ V H++ + D ++AM DG V+ + + Sbjct: 843 LSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVE 902 Query: 260 LFHKLVNEYWSYTSN 216 L+ E+W N Sbjct: 903 LY-----EHWKTLMN 912
>MRP1_HUMAN (P33527) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1531 Score = 114 bits (286), Expect = 2e-25 Identities = 57/126 (45%), Positives = 83/126 (65%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L + V LD E G N S+GQRQL CL RALLR+ +ILVLDEATA++D Sbjct: 1403 LELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDL 1462 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q TIR++F+ CTV+T+AHR+ T+MD V+ + G++ EY P+ L++ G LF Sbjct: 1463 ETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRG-LF 1521 Query: 254 HKLVNE 237 + + + Sbjct: 1522 YSMAKD 1527 Score = 46.2 bits (108), Expect = 8e-05 Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 3/132 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 + C LL ++ G + + E G N S GQ+Q L RA+ I + D+ +++D Sbjct: 741 IQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDA 800 Query: 434 ATDAVLQKTI---RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + + + K T I V H + + D+++ MS GK+ E +L+ +G Sbjct: 801 HVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDG 860 Query: 263 SLFHKLVNEYWS 228 + F + + Y S Sbjct: 861 A-FAEFLRTYAS 871
>MRP1_MACFA (Q864R9) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1531 Score = 113 bits (282), Expect = 5e-25 Identities = 54/110 (49%), Positives = 78/110 (70%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 LD E G N S+GQRQL CL RALLR+ +ILVLDEATA++D TD ++Q TIR++F+ Sbjct: 1419 LDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFED 1478 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 CTV+T+AHR+ T+MD V+ + G++ EY P+ L++ G LF+ + + Sbjct: 1479 CTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRG-LFYNMARD 1527 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 3/132 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 + C LL ++ G + + E G N S GQ+Q L RA+ I + D+ +++D Sbjct: 741 IQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCNADIYLFDDPLSAVDA 800 Query: 434 ATDAVLQKTI---RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + + + K T I V H + + D+++ MS GK+ E +L+ +G Sbjct: 801 HVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDG 860 Query: 263 SLFHKLVNEYWS 228 + F + + Y S Sbjct: 861 A-FAEFLRTYAS 871
>YBT1_YEAST (P32386) ATP-dependent bile acid permease| Length = 1661 Score = 112 bits (279), Expect = 1e-24 Identities = 55/107 (51%), Positives = 77/107 (71%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 L S + E GSN S GQRQL CL R+LLR +I++LDEATASID ++DA +Q+TIR EF+ Sbjct: 1528 LSSEISEGGSNLSQGQRQLMCLARSLLRSPKIILLDEATASIDYSSDAKIQETIRKEFQG 1587 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 T++T+AHR+ +V+D D +L M G+V EYD P L+ + S F+ + Sbjct: 1588 STILTIAHRLRSVIDYDKILVMDAGEVKEYDHPYSLLLNKQSAFYSM 1634 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/117 (24%), Positives = 59/117 (50%), Gaps = 3/117 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ C L + + G + + E G S GQ+Q L RAL R ++LD+ +++D+ Sbjct: 808 VEACGLKRDFEILKAGDLTEIGEKGITLSGGQKQRVSLARALYSNARHVLLDDCLSAVDS 867 Query: 434 ATDAVLQKTIRSE--FKYCTVITVAHRIP-TVMDCDMVLAMSDGKVVEYDKPTKLME 273 T + + + + T I V+H I T+ + ++V+ + DG+V + P +++ Sbjct: 868 HTASWIYDNCITGPLMEDRTCILVSHNIALTLRNAELVVLLEDGRVKDQGDPIDMLQ 924
>ABCC9_HUMAN (O60706) ATP-binding cassette transporter sub-family C member 9| (Sulfonylurea receptor 2) Length = 1549 Score = 110 bits (275), Expect = 3e-24 Identities = 58/124 (46%), Positives = 80/124 (64%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V+ GLD+ V E G N+S+GQRQLFCL RA +R+ IL++DEATASID Sbjct: 1422 LEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDM 1481 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 AT+ +LQK + + F TV+T+AHR+ ++MD +VL S+G +VE D L + F Sbjct: 1482 ATENILQKVVMTAFADRTVVTMAHRVSSIMDAGLVLVFSEGILVECDTVPNLFAHKNGPF 1541 Query: 254 HKLV 243 LV Sbjct: 1542 STLV 1545 Score = 52.8 bits (125), Expect = 8e-07 Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 3/135 (2%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-N 435 D C L + G + + E G N S GQRQ C+ RAL + I+ LD+ +++D + Sbjct: 786 DACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 845 Query: 434 ATDAVLQKTIRS--EFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 +D ++Q+ I + T++ V H++ + D ++AM DG V+ + + Sbjct: 846 LSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVE 905 Query: 260 LFHKLVNEYWSYTSN 216 L+ E+W N Sbjct: 906 LY-----EHWKTLMN 915
>MDR_LEITA (P21441) Multidrug resistance protein (EC 3.6.3.44) (P-glycoprotein)| Length = 1548 Score = 110 bits (274), Expect = 4e-24 Identities = 58/130 (44%), Positives = 81/130 (62%), Gaps = 1/130 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRR-CRILVLDEATASID 438 L+ L E V + +G+DS V+E GSN+S+GQRQL C+ RALL+R +++DEATA+ID Sbjct: 1396 LELVGLRERVASESEGIDSRVLEGGSNYSVGQRQLMCMARALLKRGSGFILMDEATANID 1455 Query: 437 NATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 A D +Q T+ S F TVIT+AHR+ TV D ++ M G V E P +L+ S+ Sbjct: 1456 PALDRQIQATVMSAFSAYTVITIAHRLHTVAQYDKIIVMDHGVVAEMGSPRELVMNHQSM 1515 Query: 257 FHKLVNEYWS 228 FH +V S Sbjct: 1516 FHSMVESLGS 1525 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NAT 429 CQL + + GLD+ + E G N S GQ+ L RA+ + +LD+ +++D + Sbjct: 733 CQLEADLAQFCGGLDTEIGEMGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVG 792 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVV 303 ++Q I + T + H+I + D ++ + G +V Sbjct: 793 QRIVQDVILGRLRGKTRVLATHQIHLLPLADYIVVLQHGSIV 834
>MRP1_CANFA (Q6UR05) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1531 Score = 108 bits (271), Expect = 9e-24 Identities = 55/126 (43%), Positives = 82/126 (65%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L + V L+ E G N S+GQRQL CL RALLR+ +ILVLDEATA++D Sbjct: 1403 LELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDL 1462 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TD ++Q TIR++F CTV+T+AHR+ T+MD V+ + G++ E +P+ L++ G LF Sbjct: 1463 ETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSDLLQQRG-LF 1521 Query: 254 HKLVNE 237 + + + Sbjct: 1522 YSMAKD 1527 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/132 (24%), Positives = 62/132 (46%), Gaps = 3/132 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ C LL ++ G + + E G N S GQ+Q L RA+ I + D+ +++D Sbjct: 741 IEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDA 800 Query: 434 ATDAVLQKTI---RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + + + K T + V H I + D+++ M+ GK+ E +L+ +G Sbjct: 801 HVGKHIFENVIGPKGMLKNKTRLLVTHSISYLPQVDVIIVMTGGKISEMGSYQELLARDG 860 Query: 263 SLFHKLVNEYWS 228 + F + + Y S Sbjct: 861 A-FAEFLRTYAS 871
>MRP1_BOVIN (Q8HXQ5) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1530 Score = 108 bits (271), Expect = 9e-24 Identities = 52/110 (47%), Positives = 77/110 (70%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 L+ E G N S+GQRQL CL RALLR+ +ILVLDEATA++D TD ++Q TIR++F Sbjct: 1418 LNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDD 1477 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 CTV+T+AHR+ T+MD V+ + G++ E+ P+ L++ G LF+ + + Sbjct: 1478 CTVLTIAHRLNTIMDYTRVIVLDKGEIQEWGSPSDLLQQRG-LFYSMAKD 1526 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 3/132 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ C LL ++ G + + E G N S GQ+Q L RA+ + +LD+ +++D Sbjct: 741 VEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDVYLLDDPLSAVDA 800 Query: 434 ATDAVLQKTI---RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + + + K T + V H I + D+++ MS GK+ E +L+ +G Sbjct: 801 HVGKHIFENVIGPKGLLKNKTRLLVTHAISYLPQMDVIIVMSGGKISEMGSYQELLARDG 860 Query: 263 SLFHKLVNEYWS 228 + F + + Y S Sbjct: 861 A-FAEFLRTYAS 871
>MRP1_MOUSE (O35379) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1528 Score = 107 bits (268), Expect = 2e-23 Identities = 52/110 (47%), Positives = 78/110 (70%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 L+ E G N S+GQRQL CL RALLR+ +ILVLDEATA++D TD ++Q TIR++F+ Sbjct: 1416 LNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFED 1475 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 CTV+T+AHR+ T+MD V+ + G+V E P++L++ G +F+ + + Sbjct: 1476 CTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSELLQQRG-IFYSMAKD 1524 Score = 48.1 bits (113), Expect = 2e-05 Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 ++ C LL ++ G + + E G N S GQ+Q L RA+ I + D+ +++D Sbjct: 741 MEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNSDIYLFDDPLSAVDA 800 Query: 437 NATDAVLQKTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + +K + K T I V H I + D+++ MS GK+ E +L++ +G Sbjct: 801 HVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDG 860 Query: 263 S 261 + Sbjct: 861 A 861
>YOR1_YEAST (P53049) Oligomycin resistance ATP-dependent permease YOR1| Length = 1477 Score = 105 bits (261), Expect = 1e-22 Identities = 49/107 (45%), Positives = 73/107 (68%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 LD V E+GSN+S+G+RQL L RAL+R+ +IL+LDEAT+S+D TD +Q I EF Sbjct: 1356 LDQAVEEEGSNFSLGERQLLALTRALVRQSKILILDEATSSVDYETDGKIQTRIVEEFGD 1415 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 CT++ +AHR+ T+++ D +L + G+V E+D P L E S+F + Sbjct: 1416 CTILCIAHRLKTIVNYDRILVLEKGEVAEFDTPWTLFSQEDSIFRSM 1462
>NFT1_YEAST (P36028) ABC transporter NFT1 (New full-length MRP-type transporter| 1) Length = 1558 Score = 104 bits (259), Expect = 2e-22 Identities = 56/139 (40%), Positives = 84/139 (60%), Gaps = 13/139 (9%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQ-------------GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCR 474 +++C L + E+EQ L++ V GSN S GQRQL CL R++L Sbjct: 1401 IEECDELCLIFEQEQPNFSSHKLRNRFIDLNTVVKSGGSNLSQGQRQLLCLARSMLGARN 1460 Query: 473 ILVLDEATASIDNATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYD 294 I+++DEATASID +DA +QKTIR K T++T+AHR+ +V+D D +L M G+V EYD Sbjct: 1461 IMLIDEATASIDYISDAKIQKTIRETMKNTTILTIAHRLRSVIDYDKILVMEMGRVKEYD 1520 Query: 293 KPTKLMETEGSLFHKLVNE 237 P L+ ++F++L + Sbjct: 1521 HPYTLISDRNTIFYRLCRQ 1539 Score = 44.7 bits (104), Expect = 2e-04 Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 3/136 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 + C L + ++ G+ + V + G + S GQ+Q L RA+ R L+LD+ +++D Sbjct: 765 MKSCCLDKDIKAMTAGIRTDVGDGGFSLSGGQQQRIALARAIYSSSRYLILDDCLSAVDP 824 Query: 434 ATDAVLQK--TIRSEFKYCTVITVAHRIPTVMD-CDMVLAMSDGKVVEYDKPTKLMETEG 264 T + + K T I +H I V D ++ + G+V KP+ L+++ Sbjct: 825 ETALYIYEECLCGPMMKGRTCIITSHNISLVTKRADWLVILDRGEVKSQGKPSDLIKSNE 884 Query: 263 SLFHKLVNEYWSYTSN 216 L + N+ + T N Sbjct: 885 FLRESINNDSKNTTHN 900
>YHD5_YEAST (P38735) Probable ATP-dependent permease YHL035C| Length = 1592 Score = 103 bits (256), Expect = 5e-22 Identities = 49/126 (38%), Positives = 82/126 (65%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ + + K L + + E G N S G+RQL + R+LLR +I++LDEAT+SID Sbjct: 1448 LNSEERFNSTHNKFLNLHTEIAEGGLNLSQGERQLLFIARSLLREPKIILLDEATSSIDY 1507 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 +D ++Q IRSEF T++T+AHR+ +V+D D ++ M G+V EYD+P++L++ E +F Sbjct: 1508 DSDHLIQGIIRSEFNKSTILTIAHRLRSVIDYDRIIVMDAGEVKEYDRPSELLKDERGIF 1567 Query: 254 HKLVNE 237 + + + Sbjct: 1568 YSMCRD 1573 Score = 37.4 bits (85), Expect = 0.035 Identities = 31/127 (24%), Positives = 59/127 (46%), Gaps = 3/127 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 +D C L ++ G + + E G S GQ+Q L RA+ + ++LD+ +++D+ Sbjct: 781 IDACGLKRDLEILPAGDLTEIGEKGITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDS 840 Query: 434 ATDAVLQKTIRSE--FKYCTVITVAHRIP-TVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 T + + + K T I V H + T+ + + + +GKV T+L +++G Sbjct: 841 HTAVWIYENCITGPLMKNRTCILVTHNVSLTLRNAHFAIVLENGKVKNQGTITEL-QSKG 899 Query: 263 SLFHKLV 243 K V Sbjct: 900 LFKEKYV 906
>MRP1_RAT (Q8CG09) Multidrug resistance-associated protein 1 (ATP-binding| cassette sub-family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter) Length = 1532 Score = 103 bits (256), Expect = 5e-22 Identities = 49/104 (47%), Positives = 73/104 (70%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 L+ E G N S+GQRQL CL RALLR+ +ILVLDEATA++D TD ++Q TIR++F+ Sbjct: 1420 LNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFED 1479 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 TV+T+AHR+ T+MD V+ + G++ E P++L++ G + Sbjct: 1480 STVLTIAHRLNTIMDYTRVIVLDKGEIRECGAPSELLQQRGVFY 1523 Score = 49.3 bits (116), Expect = 9e-06 Identities = 36/130 (27%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 ++ C LL ++ G + + E G N S GQ+Q L RA+ I +LD+ +++D Sbjct: 742 MEACALLPDLEILPSGDLTEIGEKGVNLSGGQKQRVSLARAVYCNSDIYLLDDPLSAVDA 801 Query: 437 NATDAVLQKTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + +K + K T I V H I + D+++ MS GK+ E +L++ +G Sbjct: 802 HVGKHIFEKVVGPMGLLKNKTRILVTHGISYLPQVDVIIVMSGGKISEMGSYQELLDRDG 861 Query: 263 SLFHKLVNEY 234 + F + V Y Sbjct: 862 A-FAEFVRTY 870
>ABC1_SCHPO (Q92337) ATP-binding cassette transporter abc1| Length = 1427 Score = 102 bits (255), Expect = 7e-22 Identities = 51/110 (46%), Positives = 75/110 (68%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 LD+ V G N+S GQRQ+ L RAL+R+ RI++LDE+TAS+D+ TD +Q+ +R+ FK+ Sbjct: 1314 LDTPVDSGGVNFSSGQRQILALARALVRKSRIVILDESTASVDDTTDRRIQQMLRAAFKH 1373 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 TV+ +AHRI T++D D VL + GK VE+ P K + T+ F K+ E Sbjct: 1374 ATVLCIAHRIKTIVDYDKVLVLDSGKTVEFGSP-KSLYTQRRAFWKMCKE 1422 Score = 34.7 bits (78), Expect = 0.23 Identities = 23/119 (19%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 C L + G +++ +GS+ S GQ+Q L RAL + + D+ +++D +T Sbjct: 683 CCLDSDLNSMNDGDLTYIHSNGSSLSGGQKQRVSLARALYSNAEVYIFDDIFSALDVSTS 742 Query: 425 AVLQKT--IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 + ++ + + ++ T+I H + + + + + P + E S F Sbjct: 743 RKIYESCFLSTLLQHKTIILFTHNVSLCLPIAENVIVLKNSTAQLVSPDSIQELVPSTF 801
>MRP6_HUMAN (O95255) Multidrug resistance-associated protein 6 (ATP-binding| cassette sub-family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E) Length = 1503 Score = 101 bits (251), Expect = 2e-21 Identities = 54/126 (42%), Positives = 77/126 (61%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V L + G + S+GQ+QL CL RALLR+ +IL+LDEATA++D Sbjct: 1375 LETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDP 1434 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+ +Q + S F CTV+ +AHR+ +VMDC VL M G+V E P +L+ +G LF Sbjct: 1435 GTELQMQAMLGSWFAQCTVLLIAHRLRSVMDCARVLVMDKGQVAESGSPAQLLAQKG-LF 1493 Query: 254 HKLVNE 237 ++L E Sbjct: 1494 YRLAQE 1499 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 3/122 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 L+ C L V +G+ + + E G N S GQ+Q L RA+ R+ + +LD+ A++D Sbjct: 726 LEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLLDDPLAALDA 785 Query: 437 NATDAVLQKTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + V + I + T I V H + + D ++ +++G + E +L++ +G Sbjct: 786 HVGQHVFNQVIGPGGLLQGTTRILVTHALHILPQADWIIVLANGAIAEMGSYQELLQRKG 845 Query: 263 SL 258 +L Sbjct: 846 AL 847
>MRP6_MOUSE (Q9R1S7) Multidrug resistance-associated protein 6 (ATP-binding| cassette sub-family C member 6) Length = 1498 Score = 99.4 bits (246), Expect = 8e-21 Identities = 52/126 (41%), Positives = 76/126 (60%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V L G + S+G +QL CL RALLR+ +IL+LDEATAS+D Sbjct: 1370 LETVQLKAFVTSLPGQLQYECAGQGDDLSVGHKQLLCLARALLRKTQILILDEATASVDP 1429 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+ +Q + F CT++ +AHR+ +VMDC VL M +G+V E P +L+ +G LF Sbjct: 1430 GTEMQMQAALERWFTQCTLLLIAHRLRSVMDCARVLVMDEGQVAESGNPAQLLAQKG-LF 1488 Query: 254 HKLVNE 237 ++L +E Sbjct: 1489 YRLAHE 1494 Score = 53.1 bits (126), Expect = 6e-07 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 LD C L V G+ + + E G N S GQ+Q L RA+ ++ I +LD+ A++D Sbjct: 724 LDACALGSDVASFPAGVHTPIGEQGMNLSGGQKQRLSLARAVYKKAAIYLLDDPLAALDA 783 Query: 437 NATDAVLQKTIRSE--FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + V ++ I + T I V H + + D +L +++G + E L++ G Sbjct: 784 HVSQQVFKQVIGPSGLLQGTTRILVTHTLHVLPQADRILVLANGTIAEMGSYQDLLQRNG 843 Query: 263 SL 258 +L Sbjct: 844 AL 845
>MRP6_RAT (O88269) Multidrug resistance-associated protein 6 (ATP-binding| cassette sub-family C member 6) (MRP-like protein 1) (MLP-1) Length = 1502 Score = 99.4 bits (246), Expect = 8e-21 Identities = 53/126 (42%), Positives = 76/126 (60%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL V L G + S+GQ+QL CL RALLR+ +IL+LDEATAS+D Sbjct: 1374 LETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDP 1433 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+ +Q + F CTV+ +AHR+ +VM+C VL M +G+V E P +L+ +G LF Sbjct: 1434 GTEIQMQAALERWFAQCTVLLIAHRLRSVMNCARVLVMDEGQVAESGSPAQLLAQKG-LF 1492 Query: 254 HKLVNE 237 ++L E Sbjct: 1493 YRLAQE 1498 Score = 52.8 bits (125), Expect = 8e-07 Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 3/122 (2%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID- 438 L+ C L V G+ + V E G N S GQ+Q L RA+ RR + ++D+ A++D Sbjct: 724 LEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRAAVYLMDDPLAALDA 783 Query: 437 NATDAVLQKTIRSE--FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + V ++ I + T I V H + + D +L +++G + E L+ G Sbjct: 784 HVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANGTIAEMGSYQDLLHRNG 843 Query: 263 SL 258 +L Sbjct: 844 AL 845
>MDLB_BUCAI (P57552) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 580 Score = 98.2 bits (243), Expect = 2e-20 Identities = 47/123 (38%), Positives = 84/123 (68%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LD L + V+ +G+ S + E+G+N S+GQ+QL + R L+ ++L+LDEATA+ID+ Sbjct: 451 LDTVHLSDLVKSMPKGIYSLLGEEGNNLSVGQKQLLAIARVLVAYPKVLILDEATANIDS 510 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+ ++QKT+ S K CT+I +AHR+ T+++ D ++ + GK+VE+ +L+ T+ S + Sbjct: 511 GTEQLIQKTLLSIRKNCTLIIIAHRLSTIIEADSIIVLKKGKIVEFGTHEQLL-TKKSCY 569 Query: 254 HKL 246 +K+ Sbjct: 570 YKM 572
>MSBA_FRANO (Q47908) Lipid A export ATP-binding/permease protein msbA| Length = 593 Score = 95.1 bits (235), Expect = 1e-19 Identities = 49/131 (37%), Positives = 80/131 (61%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L + E VQE G+ +++ +GS S GQRQ + RALL+ +L+ DEAT+++DN Sbjct: 461 LKRANAYEFVQELSDGIHTNIGNNGSKLSGGQRQRISIARALLKNAPVLIFDEATSALDN 520 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++ V+Q+ + S + CT I +AHR+ TV + D ++ M GKVVE K +L+E +G L+ Sbjct: 521 ESERVVQQALESLTESCTTIVIAHRLSTVENADKIVVMDGGKVVESGKHQELLE-QGGLY 579 Query: 254 HKLVNEYWSYT 222 +N ++ T Sbjct: 580 TGSINRDFNST 590
>MDLB_BUCAP (Q8K984) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 580 Score = 94.4 bits (233), Expect = 2e-19 Identities = 48/125 (38%), Positives = 80/125 (64%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L L VQ +G+ S + E+G+N S+GQ+QL + R L+R +IL+LDEATA+ID+ Sbjct: 451 LKTVHLSSLVQSMPKGIYSILGEEGNNLSLGQKQLLAIARILVRNPKILILDEATANIDS 510 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+ ++Q T+ S T++ +AHR+ TV++ DM++ + GK+VE +L+E +G + Sbjct: 511 GTEKLIQTTLSSIRAKTTLVVIAHRLSTVIEADMIVVLKKGKIVELGTHKQLLEKKG-FY 569 Query: 254 HKLVN 240 K+ N Sbjct: 570 WKMYN 574
>MSBA_VIBVU (Q8DAV2) Lipid A export ATP-binding/permease protein msbA| Length = 583 Score = 88.2 bits (217), Expect = 2e-17 Identities = 43/112 (38%), Positives = 71/112 (63%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E + + E GLD+ V E+G++ S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 460 MEFISKMENGLDTMVGENGASLSGGQRQRVAIARALLRDAPVLILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + K TV+ +AHR+ T+ D +L + DG VVE ++L+E +G+ Sbjct: 520 QSALDELQKNKTVLVIAHRLSTIEKADQILVIDDGSVVERGSHSELIEKDGA 571
>MDLB_ECOLI (P0AAG5) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 88.2 bits (217), Expect = 2e-17 Identities = 42/117 (35%), Positives = 72/117 (61%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL E + G+ + + E G+N S+GQ+QL L R L+ +IL+LDEATASID+ Sbjct: 450 LETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASIDS 509 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 T+ +Q + + ++ T++ +AHR+ T++D D +L + G+ VE +L+ +G Sbjct: 510 GTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG 566
>MDLB_ECOL6 (P0AAG6) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 88.2 bits (217), Expect = 2e-17 Identities = 42/117 (35%), Positives = 72/117 (61%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL E + G+ + + E G+N S+GQ+QL L R L+ +IL+LDEATASID+ Sbjct: 450 LETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASIDS 509 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 T+ +Q + + ++ T++ +AHR+ T++D D +L + G+ VE +L+ +G Sbjct: 510 GTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG 566
>MDLB_ECO57 (P0AAG7) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 593 Score = 88.2 bits (217), Expect = 2e-17 Identities = 42/117 (35%), Positives = 72/117 (61%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ QL E + G+ + + E G+N S+GQ+QL L R L+ +IL+LDEATASID+ Sbjct: 450 LETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASIDS 509 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 T+ +Q + + ++ T++ +AHR+ T++D D +L + G+ VE +L+ +G Sbjct: 510 GTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG 566
>MSBA_VIBVY (Q7MJ07) Lipid A export ATP-binding/permease protein msbA| Length = 583 Score = 87.4 bits (215), Expect = 3e-17 Identities = 43/112 (38%), Positives = 71/112 (63%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E + + E GLD+ V E+G++ S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 460 MEFISKMENGLDTVVGENGASLSGGQRQRVAIARALLRDAPVLILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + K TV+ +AHR+ T+ D +L + DG VVE ++L+E +G+ Sbjct: 520 QSALDELQKNKTVLVIAHRLSTIEKADQILVIDDGAVVERGSHSELIEKDGA 571
>MSBA_HAEDU (Q7VL52) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 86.3 bits (212), Expect = 7e-17 Identities = 42/112 (37%), Positives = 71/112 (63%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E +++ EQGLD+ + E+G++ S GQRQ + RALLR +LVLDEAT+++D ++ + Sbjct: 460 MEFIEKLEQGLDTVIGENGASLSGGQRQRLAIARALLRNAPVLVLDEATSALDTESELAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + + K TV+ +AHR+ T+ D +L + GK+VE +L+ G+ Sbjct: 520 QSALAALQKNKTVLVIAHRLSTIEKADEILVVDQGKIVERGSHEQLLAKGGA 571
>MSBA_WIGBR (Q8D2U8) Lipid A export ATP-binding/permease protein msbA| Length = 581 Score = 85.5 bits (210), Expect = 1e-16 Identities = 43/111 (38%), Positives = 71/111 (63%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + + GL++ + E+G+ S GQRQ + RALLR C IL+LDEAT+++D ++ + Sbjct: 459 MDFIIKMKHGLNTIIGENGTLLSGGQRQRIAIARALLRDCPILILDEATSALDIESEIKV 518 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 QK I K T + +AHRI T+ DM+L + GK++EY +L+E +G Sbjct: 519 QKAIDKIRKNRTSLVIAHRISTIKKSDMILLVEKGKIIEYGNHNELIEKKG 569
>HEPA_ANASP (P22638) Heterocyst differentiation ATP-binding protein hepA| Length = 607 Score = 85.1 bits (209), Expect = 1e-16 Identities = 44/122 (36%), Positives = 75/122 (61%), Gaps = 2/122 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 L+ ++E +G D+ + + G S GQRQ + RALLR IL+LDEAT+++D+ ++ ++ Sbjct: 480 LQFIEEMPEGFDTKLGDRGVRLSGGQRQRIAIARALLRDPEILILDEATSALDSVSERLI 539 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL--FHKLV 243 Q++I TVI +AHR+ T+ D V+ M G++VE +L+E G L +H++ Sbjct: 540 QESIEKLSVGRTVIAIAHRLSTIAKADKVVVMEQGRIVEQGNYQELLEQRGKLWKYHQMQ 599 Query: 242 NE 237 +E Sbjct: 600 HE 601
>EXP8_STRPN (P35598) Putative ABC transporter ATP-binding protein exp8| (Exported protein 8) Length = 583 Score = 84.7 bits (208), Expect = 2e-16 Identities = 42/114 (36%), Positives = 71/114 (62%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 +QE QG DS V E GS++S GQRQL R + + +IL+LDEATA+ID+ T++++Q + Sbjct: 459 IQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETESLVQAS 518 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + + T I +AHR+ T+ D + + + G+++E +L+ G +HK+ Sbjct: 519 LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLAL-GGTYHKM 571
>CFTR_PAPAN (Q9TSP5) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFR 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 1/125 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ CQL E + + + + + E G S GQR L RA+ + + +LD +D Sbjct: 521 INACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 580 Query: 434 ATD-AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T+ + + + T I V ++ + D +L + +G Y ++L Sbjct: 581 LTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDF 640 Query: 257 FHKLV 243 KL+ Sbjct: 641 SSKLM 645
>CFTR_MACNE (Q9TUQ2) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFQ 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 1/125 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ CQL E + + + + + E G S GQR L RA+ + + +LD +D Sbjct: 521 INACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 580 Query: 434 ATD-AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T+ + + + T I V ++ + D +L + +G Y ++L Sbjct: 581 LTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDF 640 Query: 257 FHKLV 243 KL+ Sbjct: 641 SSKLM 645
>CFTR_MACMU (Q00553) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFR 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 1/125 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ CQL E + + + + + E G S GQR L RA+ + + +LD +D Sbjct: 521 INACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 580 Query: 434 ATD-AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T+ + + + T I V ++ + D +L + +G Y ++L Sbjct: 581 LTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDF 640 Query: 257 FHKLV 243 KL+ Sbjct: 641 SSKLM 645
>CFTR_MACFU (Q7JII7) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFR 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 1/125 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ CQL E + + + + + E G S GQR L RA+ + + +LD +D Sbjct: 521 INACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 580 Query: 434 ATD-AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T+ + + + T I V ++ + D +L + +G Y ++L Sbjct: 581 LTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDF 640 Query: 257 FHKLV 243 KL+ Sbjct: 641 SSKLM 645
>CFTR_MACFA (Q7JII8) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFR 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 1/125 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ CQL E + + + + + E G S GQR L RA+ + + +LD +D Sbjct: 521 INACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 580 Query: 434 ATD-AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL 258 T+ + + + T I V ++ + D +L + +G Y ++L Sbjct: 581 LTEKEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDF 640 Query: 257 FHKLV 243 KL+ Sbjct: 641 SSKLM 645
>CFTR_HORSE (Q2QLA3) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 75/124 (60%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G+ S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGNVLSHGHKQLICLARSVLSKAKILLLDEPSAHLDPI 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ +E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKVRQYDSIQKLL-SEKSLFQ 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 31.6 bits (70), Expect = 1.9 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 523 CQLEEDISKFAEKDNIVLGEGGIQLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 582 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 583 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSK 642 Query: 248 LV 243 L+ Sbjct: 643 LM 644
>CFTR_PONPY (Q2IBE4) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1320 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1379 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1380 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFQ 1438 Query: 251 KLVN 240 + ++ Sbjct: 1439 QAIS 1442 Score = 31.6 bits (70), Expect = 1.9 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>CFTR_HUMAN (P13569) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 84.0 bits (206), Expect = 3e-16 Identities = 43/124 (34%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1320 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1379 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1380 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFR 1438 Query: 251 KLVN 240 + ++ Sbjct: 1439 QAIS 1442 Score = 32.3 bits (72), Expect = 1.1 Identities = 27/122 (22%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L + K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLQPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>ATM1_YEAST (P40416) Transporter ATM1, mitochondrial precursor| Length = 690 Score = 82.8 bits (203), Expect = 7e-16 Identities = 44/125 (35%), Positives = 73/125 (58%), Gaps = 2/125 (1%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++K QL +++ QG D+ V E G S G++Q + R LL+ RI+ DEAT+++D Sbjct: 546 VEKAQLAPLIKKLPQGFDTIVGERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDT 605 Query: 434 ATDAVLQKTIRSEFK--YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 T+ L +TIR F T + +AHR+ T+ D D ++ + +G+V E K +L+ GS Sbjct: 606 HTEQALLRTIRDNFTSGSRTSVYIAHRLRTIADADKIIVLDNGRVREEGKHLELLAMPGS 665 Query: 260 LFHKL 246 L+ +L Sbjct: 666 LYREL 670
>MSBA_VIBCH (Q9KQW9) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 82.4 bits (202), Expect = 1e-15 Identities = 38/112 (33%), Positives = 70/112 (62%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E ++ QGLD+ + E+G++ S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 460 MEFIENMPQGLDTVIGENGTSLSGGQRQRVAIARALLRDAPVLILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + K TV+ +AHR+ T+ D +L + +G+++E + L+ +G+ Sbjct: 520 QAALDELQKNKTVLVIAHRLSTIEQADEILVVDEGEIIERGRHADLLAQDGA 571
>MSBA_PASMU (Q9CMG7) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 82.4 bits (202), Expect = 1e-15 Identities = 44/122 (36%), Positives = 73/122 (59%), Gaps = 3/122 (2%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E +++ E GLD+ + E+G N S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 460 MEFIEKLEHGLDTVIGENGVNLSGGQRQRLAIARALLRNSPVLILDEATSALDTESERSI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS---LFHKL 246 Q + K TVI +AHR+ T+ + D +L + G++ E ++L+ G+ L H Sbjct: 520 QLALEKLQKERTVIVIAHRLSTIENADEILVIEHGEIKERGSHSELLALNGAYKQLHHIQ 579 Query: 245 VN 240 VN Sbjct: 580 VN 581
>CFTR_PANTR (Q2QLE5) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 82.0 bits (201), Expect = 1e-15 Identities = 42/124 (33%), Positives = 72/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1320 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1379 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 ++++T++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1380 AYQIIRRTLKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NERSLFR 1438 Query: 251 KLVN 240 + ++ Sbjct: 1439 QAIS 1442 Score = 31.6 bits (70), Expect = 1.9 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>CFTR_CALMO (Q2QLB4) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 82.0 bits (201), Expect = 1e-15 Identities = 42/124 (33%), Positives = 72/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1320 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1379 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++ ++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1380 TYQIIRRALKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NEKSLFQ 1438 Query: 251 KLVN 240 + ++ Sbjct: 1439 QAIS 1442 Score = 31.6 bits (70), Expect = 1.9 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>CFTR_CALJA (Q2QLF9) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 81.6 bits (200), Expect = 2e-15 Identities = 42/124 (33%), Positives = 72/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRTVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPV 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++ ++ F CTVI HRI +++C L + + KV +YD KL+ E SLF Sbjct: 1381 TYQIIRRALKQAFADCTVILCEHRIEAMLECQQFLVIEENKVRQYDSIQKLL-NEKSLFR 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 31.6 bits (70), Expect = 1.9 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>MSBA_ERWCT (Q6D437) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 81.6 bits (200), Expect = 2e-15 Identities = 40/112 (35%), Positives = 67/112 (59%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + E GLD+ + E+G S GQRQ + RALLR IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMEHGLDTVIGENGVMLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + K T + +AHR+ T+ D +L + DG+++E T L+ T G+ Sbjct: 520 QAALDELQKDRTALVIAHRLSTIEKADEILVVEDGRIIERGNHTALLATNGA 571
>MSBA_XANCP (Q8P8W4) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/115 (36%), Positives = 64/115 (55%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E V + +GL SHV G S GQRQ + RA+L+ IL+LDEATA++DN ++ ++ Sbjct: 464 MEFVAQLPEGLQSHVGTKGGRLSGGQRQRLAIARAMLKDAPILILDEATAALDNESERLV 523 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 Q + T + +AHR+ T+ D VL M G++VE +L+ G H Sbjct: 524 QDALHKLMPDRTTLVIAHRLSTIEHADQVLVMDQGRIVERGTHQELLALGGLYSH 578
>MDR3_CRIGR (P23174) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein 3) Length = 1281 Score = 81.3 bits (199), Expect = 2e-15 Identities = 44/118 (37%), Positives = 72/118 (61%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + + Q D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++A +Q Sbjct: 513 EFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQ 572 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ TV + D++ DG +VE ++LM+ EG ++ KLVN Sbjct: 573 AALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMQKEG-VYFKLVN 629 Score = 73.2 bits (178), Expect = 6e-13 Identities = 36/116 (31%), Positives = 72/116 (62%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++ Q + V + G+ S GQ+Q + RAL+R+ R+L+LDEAT+++D ++ V+Q+ Sbjct: 1159 IETLPQKYKTRVGDKGTQLSGGQKQRLAIRRALIRQPRVLLLDEATSALDTESEKVVQEA 1218 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ T+ + D+++ + +GKV E+ +L+ +G ++ +VN Sbjct: 1219 LDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKG-IYFSMVN 1273
>CFTR_SHEEP (Q00555) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 81.3 bits (199), Expect = 2e-15 Identities = 41/124 (33%), Positives = 74/124 (59%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPI 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD +++ +E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKVRQYDSIQRML-SEKSLFR 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 34.3 bits (77), Expect = 0.30 Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 523 CQLEEDISKFSEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 582 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G V Y ++L K Sbjct: 583 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSVYFYGTFSELQNQRPDFSSK 642 Query: 248 LV 243 L+ Sbjct: 643 LM 644
>CFTR_MICMU (Q2QL83) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 81.3 bits (199), Expect = 2e-15 Identities = 42/124 (33%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1321 DEVGLRSVIEQFPGKLDFVLVDGGYVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPI 1380 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + V +YD KL+ +E SLF Sbjct: 1381 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQRFLVIEENNVRQYDSIQKLL-SEKSLFR 1439 Query: 251 KLVN 240 + ++ Sbjct: 1440 QAIS 1443 Score = 31.2 bits (69), Expect = 2.5 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDIAKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>RTX1B_ACTPL (P26760) Toxin RTX-I translocation ATP-binding protein (RTX-I toxin| determinant B) (APX-IB) (HLY-IB) (Cytolysin IB) (CLY-IB) Length = 707 Score = 80.9 bits (198), Expect = 3e-15 Identities = 40/116 (34%), Positives = 68/116 (58%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ Sbjct: 586 EFISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIM 645 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + + K TVI +AHR+ TV + D ++ M G++VE K +L+ L+H L Sbjct: 646 RNMHQICKGRTVIIIAHRLSTVKNADRIIVMEKGQIVEQGKHKELLADPNGLYHYL 701
>MSBA_PSESM (Q87VF3) Lipid A export ATP-binding/permease protein msbA| Length = 600 Score = 80.9 bits (198), Expect = 3e-15 Identities = 41/110 (37%), Positives = 64/110 (58%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + + QG D+ V E+G S GQRQ + RALL+ +L+LDEAT+++D ++ +Q Sbjct: 472 EFIDQLPQGFDTQVGENGVLLSGGQRQRLAIARALLKNAPLLILDEATSALDTESERHIQ 531 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + K T + +AHR+ T+ DM+L M GK+VE T+L+ G Sbjct: 532 AALDHVMKGRTTLVIAHRLSTIEKADMILVMDAGKIVERGTHTELLAQNG 581
>MDR3_HUMAN (P21439) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein 3) Length = 1279 Score = 80.9 bits (198), Expect = 3e-15 Identities = 44/118 (37%), Positives = 72/118 (61%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + + Q D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++A +Q Sbjct: 513 EFIMKLPQKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQ 572 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ TV + D++ DG +VE ++LM+ EG ++ KLVN Sbjct: 573 AALDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELMKKEG-VYFKLVN 629 Score = 70.9 bits (172), Expect = 3e-12 Identities = 33/103 (32%), Positives = 65/103 (63%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYC 384 ++ V + G+ S GQ+Q + RAL+R+ +IL+LDEAT+++D ++ V+Q+ + + Sbjct: 1165 ETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDKAREGR 1224 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T I +AHR+ T+ + D+++ +G+V E+ +L+ +G F Sbjct: 1225 TCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYF 1267
>MSBA_YERPS (Q66CI3) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 80.9 bits (198), Expect = 3e-15 Identities = 39/111 (35%), Positives = 67/111 (60%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + E GLD+ + E+G S GQRQ + RALLR C IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMEHGLDTVIGENGIMLSGGQRQRIAIARALLRNCPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 Q + K T + +AHR+ T+ D ++ + DG++VE +L+ +G Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEKADEIVVIEDGRIVERGVHAELLVQQG 570
>MSBA_YERPE (Q8ZGA9) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 80.9 bits (198), Expect = 3e-15 Identities = 39/111 (35%), Positives = 67/111 (60%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + E GLD+ + E+G S GQRQ + RALLR C IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMEHGLDTVIGENGIMLSGGQRQRIAIARALLRNCPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 Q + K T + +AHR+ T+ D ++ + DG++VE +L+ +G Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEKADEIVVIEDGRIVERGVHAELLVQQG 570
>MSBA_VIBPA (Q87R16) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 80.9 bits (198), Expect = 3e-15 Identities = 39/112 (34%), Positives = 67/112 (59%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E + + E GLD+ + E+G++ S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 460 MEFINKMENGLDTMIGENGASLSGGQRQRVAIARALLRDAPVLILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + K TV+ +AHR+ T+ D +L + DG ++E L+ G+ Sbjct: 520 QAALDELQKDKTVLVIAHRLSTIEKADEILVVDDGAIIERGNHADLIAKNGA 571
>MDR4_ARATH (O80725) Multidrug resistance protein 4 (P-glycoprotein 4)| Length = 1286 Score = 80.5 bits (197), Expect = 4e-15 Identities = 42/115 (36%), Positives = 70/115 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 V + QGLD+ V E G+ S GQ+Q + RA+L+ RIL+LDEAT+++D ++ V+Q+ Sbjct: 505 VDKLPQGLDTMVGEHGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERVVQEA 564 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + T + VAHR+ TV + DM+ + GK+VE T+L++ + +L+ Sbjct: 565 LDRIMVNRTTVVVAHRLSTVRNADMIAVIHQGKIVEKGSHTELLKDPEGAYSQLI 619 Score = 70.1 bits (170), Expect = 5e-12 Identities = 36/111 (32%), Positives = 65/111 (58%) Frame = -2 Query: 575 EQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSE 396 +QG D+ V E G S GQ+Q + RA+++ ++L+LDEAT+++D ++ V+Q + Sbjct: 1168 QQGYDTMVGERGIQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRV 1227 Query: 395 FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I VAHR+ T+ + D++ + +G +VE K L+ + ++ LV Sbjct: 1228 MVNRTTIVVAHRLSTIKNADVIAVVKNGVIVEKGKHDTLINIKDGVYASLV 1278
>CFTR_PIG (Q6PQZ2) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1482 Score = 80.5 bits (197), Expect = 4e-15 Identities = 44/120 (36%), Positives = 74/120 (61%), Gaps = 1/120 (0%) Frame = -2 Query: 596 LEAVQEKEQG-LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAV 420 L +V E+ G LD +V+ G S G +QL CL R++L + +IL+LDE +A +D T + Sbjct: 1326 LRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLGKAKILLLDEPSAHLDPITYQI 1385 Query: 419 LQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 +++T++ F CTVI HRI +++C L + + KV +YD +L+ +E SLF + ++ Sbjct: 1386 IRRTLKQAFADCTVILSEHRIEAMLECQRFLVIEENKVRQYDSIQRLL-SEKSLFRQAIS 1444 Score = 31.6 bits (70), Expect = 1.9 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQSQRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>MSBA_XANAC (Q8PKS5) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 80.5 bits (197), Expect = 4e-15 Identities = 41/115 (35%), Positives = 64/115 (55%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E V + +GL SHV G S GQRQ + RA+L+ +L+LDEATA++DN ++ ++ Sbjct: 464 MEFVAQLPEGLQSHVGTKGGRLSGGQRQRLAIARAMLKDAPVLILDEATAALDNESERLV 523 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 Q + T + +AHR+ T+ D VL M G++VE +L+ G H Sbjct: 524 QDALHKLMPDRTTLVIAHRLSTIEHADQVLVMDQGRIVERGTHHQLLAQGGLYSH 578
>Y288_THEMA (Q9WYC4) Hypothetical ABC transporter ATP-binding protein TM0288| Length = 598 Score = 80.1 bits (196), Expect = 5e-15 Identities = 36/118 (30%), Positives = 71/118 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++ +G ++ + ++G + S GQRQL + RA L +IL+LDEAT+++D T+ +Q Sbjct: 474 IKHLPEGYETVLTDNGEDLSQGQRQLLAITRAFLANPKILILDEATSNVDTKTEKSIQAA 533 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 + + T I +AHR+ T+ + D+++ + DG++VE K +L++ G + ++Y Sbjct: 534 MWKLMEGKTSIIIAHRLNTIKNADLIIVLRDGEIVEMGKHDELIQKRGFYYELFTSQY 591
>MSBA_NEIMB (Q9JXR3) Lipid A export ATP-binding/permease protein msbA| Length = 621 Score = 80.1 bits (196), Expect = 5e-15 Identities = 41/117 (35%), Positives = 65/117 (55%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L L + GL + +GSN S GQRQ + RA+L+ IL+LDEAT+++DN Sbjct: 487 LQTANLQSLIDSSPLGLHQPIGSNGSNLSGGQRQRVAIARAILKDAPILLLDEATSALDN 546 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ++ ++Q+ + + T I VAHR+ T+ D ++ M DGK++E +LM G Sbjct: 547 ESERLVQQALERLMENRTGIIVAHRLTTIEGADRIIVMDDGKIIEQGTHEQLMSQNG 603
>CFTR_BOVIN (P35071) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1481 Score = 80.1 bits (196), Expect = 5e-15 Identities = 43/120 (35%), Positives = 73/120 (60%), Gaps = 1/120 (0%) Frame = -2 Query: 596 LEAVQEKEQG-LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAV 420 L AV E+ G LD +V+ G S G +QL CL R++L + +IL+LDE +A +D T + Sbjct: 1325 LRAVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQI 1384 Query: 419 LQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 +++T++ F CTVI HRI +++C + + KV +YD +++ +E SLF + ++ Sbjct: 1385 IRRTLKQAFANCTVILSEHRIEAMLECQRFFVIEENKVRQYDSIQRML-SEKSLFRQAIS 1443 Score = 33.9 bits (76), Expect = 0.39 Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 523 CQLEEDISKFAEKDNVVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 582 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + I T I V ++ + D +L + +G + Y ++L K Sbjct: 583 KEIFESCICKLMANKTRILVTSKMEHLKKADKILILHEGSIYFYGTFSELQNQRPDFSSK 642 Query: 248 LV 243 L+ Sbjct: 643 LM 644
>MSBA_NEIMA (Q9JW59) Lipid A export ATP-binding/permease protein msbA| Length = 621 Score = 79.7 bits (195), Expect = 6e-15 Identities = 41/117 (35%), Positives = 65/117 (55%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L L + GL + +GSN S GQRQ + RA+L+ IL+LDEAT+++DN Sbjct: 487 LQAANLQSLIDASPLGLHQPIGSNGSNLSGGQRQRVAIARAILKDAPILLLDEATSALDN 546 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ++ ++Q+ + + T I VAHR+ T+ D ++ M DGK++E +LM G Sbjct: 547 ESERLVQQALERLMENRTGIIVAHRLTTIEGADRIIVMDDGKIIEQGTHEQLMSQNG 603
>CFTR_DIDMA (Q2QL74) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1482 Score = 79.7 bits (195), Expect = 6e-15 Identities = 41/124 (33%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1322 DEVGLKSVIEQFPGKLDFVLVDGGYVLSHGHKQLICLARSVLSKAKILLLDEPSAHLDPI 1381 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++ +++ F CTVI HRI +++C L + D KV +Y+ KL+ E SL+ Sbjct: 1382 TYQIIRRVLKNAFANCTVILSEHRIEAMLECQRFLVIEDNKVRQYESIQKLV-NEKSLYR 1440 Query: 251 KLVN 240 + ++ Sbjct: 1441 QAIS 1444 Score = 33.1 bits (74), Expect = 0.66 Identities = 26/122 (21%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + ++ + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNTVLGEGGITLSGGQRARISLARAIYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I + ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILITSKMEHLKKADKILILHEGSCYFYGAFSELQNLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>RTX3B_ACTPL (Q04473) Toxin RTX-III translocation ATP-binding protein (RTX-III| toxin determinant B) (APX-IIIB) (Cytolysin IIIB) (CLY-IIIB) Length = 711 Score = 79.3 bits (194), Expect = 8e-15 Identities = 40/114 (35%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ RIL+ DEAT+++D ++ ++ + Sbjct: 592 ISELREGYNTIVGELGAGLSGGQRQRIAIARALVNNPRILIFDEATSALDYESEHIIMQN 651 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ TVI +AHR+ TV + D ++ M G +VE K +L+E E L++ L Sbjct: 652 MQKICHGRTVIIIAHRLSTVKNADRIIVMEKGHIVEQGKHNQLLENENGLYYYL 705
>HLYB_PROVU (P11599) Alpha-hemolysin translocation ATP-binding protein hlyB| Length = 707 Score = 79.3 bits (194), Expect = 8e-15 Identities = 39/114 (34%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ V+ + Sbjct: 588 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHVIMRN 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + + TVI +AHR+ TV + D ++ M G+++E K +L+ SL+H L Sbjct: 648 MHKICQGRTVIIIAHRLSTVKNADRIIVMEKGQIIEQGKHKELLSDPESLYHYL 701
>HLYBP_ECOLI (P08716) Alpha-hemolysin translocation ATP-binding protein hlyB| Length = 707 Score = 79.3 bits (194), Expect = 8e-15 Identities = 41/114 (35%), Positives = 67/114 (58%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ V+ + Sbjct: 588 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHVIMRN 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + K TVI +AHR+ TV + D ++ M GK+VE K +L+ SL+ L Sbjct: 648 MHKICKGRTVIIIAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYL 701
>HLYBC_ECOLI (P10089) Alpha-hemolysin translocation ATP-binding protein hlyB| Length = 707 Score = 79.3 bits (194), Expect = 8e-15 Identities = 41/114 (35%), Positives = 67/114 (58%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ V+ + Sbjct: 588 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHVIMRN 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + K TVI +AHR+ TV + D ++ M GK+VE K +L+ SL+ L Sbjct: 648 MHKICKGRTVIIIAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYL 701
>Y1051_HAEIN (Q57180) Hypothetical ABC transporter ATP-binding protein HI1051| Length = 614 Score = 79.3 bits (194), Expect = 8e-15 Identities = 42/120 (35%), Positives = 71/120 (59%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G D+HV E G S GQRQ + R +L+ IL+LDEAT+++D+ + +Q+++ Sbjct: 493 KGYDAHVGERGVKLSGGQRQRIAIARVMLKDAPILLLDEATSALDSEVEVAIQESLDKMM 552 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEYWSYTSNG 213 + TVI +AHR+ T+ D ++ + G++VE +L+E G L+ KL W++ S G Sbjct: 553 ENKTVIAIAHRLSTIAAMDRLIVLDKGQIVEQGTHAELLELNG-LYAKL----WNHQSGG 607
>MDR1_CAEEL (P34712) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| A) Length = 1321 Score = 79.3 bits (194), Expect = 8e-15 Identities = 40/117 (34%), Positives = 74/117 (63%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V + G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++ V+Q+ Sbjct: 1200 IAELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEKVVQEA 1259 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 + + T I +AHR+ TVM+ D + +S+G ++E T+LM +G+ ++KL + Sbjct: 1260 LDRAREGRTCIVIAHRLNTVMNADCIAVVSNGTIIEKGTHTQLMSEKGA-YYKLTQK 1315 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/124 (32%), Positives = 75/124 (60%), Gaps = 3/124 (2%) Frame = -2 Query: 605 CQLLEA---VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 C++ A ++ G ++ V + G+ S GQ+Q + RAL+R +IL+LDEAT+++D Sbjct: 528 CKMANAEKFIKTLPNGYNTLVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDA 587 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++ ++Q+ + K T I +AHR+ T+ + D++++ +G+VVE LM +G L+ Sbjct: 588 ESEGIVQQALDKAAKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQG-LY 646 Query: 254 HKLV 243 + LV Sbjct: 647 YDLV 650
>CFTR_RABIT (Q00554) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1480 Score = 79.3 bits (194), Expect = 8e-15 Identities = 41/124 (33%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1320 DEVGLRSVIEQFPGKLDFVLVDGGYVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPI 1379 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + V +Y+ KL+ +E SLF Sbjct: 1380 TYQIIRRTLKQAFADCTVILCEHRIEAMLECQRFLVIEENTVRQYESIQKLL-SEKSLFR 1438 Query: 251 KLVN 240 + ++ Sbjct: 1439 QAIS 1442 Score = 32.7 bits (73), Expect = 0.87 Identities = 27/122 (22%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + ++ + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFTEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQSLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>CFTR_SQUAC (P26362) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1492 Score = 79.0 bits (193), Expect = 1e-14 Identities = 41/118 (34%), Positives = 69/118 (58%) Frame = -2 Query: 599 LLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAV 420 L +++ L+ +V+ G S G +QL CL R++L + +IL+LDE TA +D T + Sbjct: 1334 LKSMIEQFPDKLNFVLVDGGYILSNGHKQLMCLARSILSKAKILLLDEPTAHLDPVTFQI 1393 Query: 419 LQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++KT++ F CTVI HR+ +++C L + V ++D KL+ TE SLF ++ Sbjct: 1394 IRKTLKHTFSNCTVILSEHRVEALLECQQFLVIEGCSVKQFDALQKLL-TEASLFKQV 1450 Score = 29.3 bits (64), Expect = 9.6 Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ CQL E + + + + G S GQR L RAL + + +LD + +D Sbjct: 522 VNACQLEEDITVFPNKDKTVLGDGGITLSGGQRARISLARALYKDADLYLLDSPFSHLDV 581 Query: 434 ATDA-VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEY 297 T+ + + + T I V ++ + D +L + +G Y Sbjct: 582 TTEKDIFESCLCKLMVNKTRILVTSKLEHLKKADKILLLHEGHCYFY 628
>PAXB_PASAE (Q9RCG7) Exotoxin translocation ATP-binding protein paxB (EC| 3.6.3.43) Length = 711 Score = 79.0 bits (193), Expect = 1e-14 Identities = 39/114 (34%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ RIL+ DEAT+++D ++ ++ + Sbjct: 592 ISELREGYNTMVGEQGAGLSGGQRQRIAIARALVNNPRILIFDEATSALDYESEHIIMRN 651 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ TVI +AHR+ TV D ++ M G +VE K ++L+E + L++ L Sbjct: 652 MQQICHGRTVIIIAHRLSTVRKADRIIVMEKGHIVERGKHSELLENKDGLYYYL 705
>HLYB_ECOL6 (Q8FDZ8) Alpha-hemolysin translocation ATP-binding protein hlyB| Length = 707 Score = 79.0 bits (193), Expect = 1e-14 Identities = 40/114 (35%), Positives = 67/114 (58%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 588 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMRN 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + K TVI +AHR+ TV + D ++ M GK+VE K +L+ SL+ L Sbjct: 648 MHKICKGRTVIIIAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYL 701
>HLYB3_ECOLI (Q47258) Alpha-hemolysin translocation ATP-binding protein hlyB| Length = 707 Score = 79.0 bits (193), Expect = 1e-14 Identities = 40/114 (35%), Positives = 67/114 (58%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 588 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMRN 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + K TVI +AHR+ TV + D ++ M GK+VE K +L+ SL+ L Sbjct: 648 MHKICKGRTVIIIAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYL 701
>CFTR_CARPS (Q2QLC5) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1482 Score = 79.0 bits (193), Expect = 1e-14 Identities = 41/124 (33%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +++ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1322 DEVGLRSVIEQFPGKLDFVLLDGGFVLSHGHKQLLCLARSVLSKAKILLLDEPSAHLDPI 1381 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + + KV +YD KL+ +E LF Sbjct: 1382 TYQIIRRTLKQAFADCTVILSEHRIEAMLECQQFLVIEENKVRQYDSLQKLL-SEKILFQ 1440 Query: 251 KLVN 240 + ++ Sbjct: 1441 QAMS 1444 Score = 36.2 bits (82), Expect = 0.078 Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR CL RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNVVLGEGGLTLSGGQRARICLARAVYKDADLYLLDSPFGHLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D +L + +G Y ++L K Sbjct: 584 KQIFESCVCKLMANKTRILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLRPDFHSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>MDR16_ARATH (Q9FWX8) Multidrug resistance protein 16 (P-glycoprotein 12)| Length = 1229 Score = 79.0 bits (193), Expect = 1e-14 Identities = 39/110 (35%), Positives = 68/110 (61%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 QGLD+ V E G+ S GQ+Q + RA+L+ R+L+LDEAT+++D ++ V+Q+ + Sbjct: 450 QGLDTKVGEHGTQLSGGQKQRIAIARAILKDPRVLLLDEATSALDTESERVVQEALDRVM 509 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T + VAHR+ TV + DM+ + GK+VE ++L++ + +L+ Sbjct: 510 VNRTTVVVAHRLSTVRNADMIAVIHSGKMVEKGSHSELLKDSVGAYSQLI 559 Score = 68.9 bits (167), Expect = 1e-11 Identities = 34/111 (30%), Positives = 65/111 (58%) Frame = -2 Query: 575 EQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSE 396 +QG D+ V E G S GQ+Q + RA+++ +IL+LDEAT+++D ++ ++Q + Sbjct: 1111 QQGYDTVVGEKGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERLVQDALDRV 1170 Query: 395 FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T + VAHR+ T+ + D++ + +G + E L++ +G ++ LV Sbjct: 1171 IVNRTTVVVAHRLSTIKNADVIAIVKNGVIAENGTHETLIKIDGGVYASLV 1221
>MSBA_CHRVO (Q7NZU6) Lipid A export ATP-binding/permease protein msbA| Length = 584 Score = 79.0 bits (193), Expect = 1e-14 Identities = 38/117 (32%), Positives = 72/117 (61%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E ++ GL++ + E+G+ S GQRQ + RALL+ +L+LDEAT+++D ++ ++ Sbjct: 458 MEFIEGLPDGLETVIGENGARLSGGQRQRLAIARALLKNAPLLILDEATSALDTQSERLV 517 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 Q + + K T I +AHR+ T+ + D ++ M G++ E + L+E +G L+ +L Sbjct: 518 QAALENLMKNRTTIVIAHRLSTIENADRIVVMHQGRLAEQGRHQALLE-QGGLYARL 573
>ABCBA_HUMAN (Q9NRK6) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2) Length = 738 Score = 79.0 bits (193), Expect = 1e-14 Identities = 39/112 (34%), Positives = 68/112 (60%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 QG ++ V E G S GQ+Q + RALL+ +IL+LDEAT+++D + ++Q+ + Sbjct: 621 QGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLM 680 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 TV+ +AHR+ T+ + +MV + GK+ EY K +L+ ++ KL+N+ Sbjct: 681 DGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNK 732
>MSBA_MANSM (Q65U21) Lipid A export ATP-binding/permease protein msbA| Length = 585 Score = 78.6 bits (192), Expect = 1e-14 Identities = 40/119 (33%), Positives = 70/119 (58%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E ++ E GLD+ + E+G++ S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 463 MEFIEPLENGLDTVIGENGASLSGGQRQRLAIARALLRDSPVLILDEATSALDTESERAI 522 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSL--FHKL 246 Q + K TV+ +AHR+ T+ D +L + G++ E +L+ G+ HK+ Sbjct: 523 QAALEELQKDRTVLVIAHRLSTIEKADEILVIDHGEICERGSHEELLALNGAYKQLHKM 581
>MSBA_BLOFL (Q7VR44) Lipid A export ATP-binding/permease protein msbA| Length = 583 Score = 77.8 bits (190), Expect = 2e-14 Identities = 40/108 (37%), Positives = 64/108 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + + G D+ V E+G S GQRQ + RALLR C IL+LDEAT+S+D ++ ++ K+ Sbjct: 465 ISKMKNGFDTIVGENGILLSNGQRQRIAIARALLRNCPILILDEATSSLDTESECIIYKS 524 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 I K T + +AHR+ T+ + D +L + G +VE L+ +G Sbjct: 525 INILKKNRTSLIIAHRLSTIENADEILVVERGSIVERGIHVDLLNHKG 572
>CFTR_CANFA (Q5U820) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1483 Score = 77.8 bits (190), Expect = 2e-14 Identities = 39/123 (31%), Positives = 73/123 (59%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++LR+ +IL+LDE +A +D Sbjct: 1323 DEVGLRSVIEQFPGKLDFVLVDGGYVLSHGHKQLMCLARSVLRKAKILLLDEPSAHLDPI 1382 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++T++ F CTVI HRI +++C L + D ++ +++ +L+ +E S F Sbjct: 1383 TYQIIRRTLKQAFADCTVILSEHRIEAMLECQRFLVIEDSRLRQFESIQRLL-SERSAFR 1441 Query: 251 KLV 243 + + Sbjct: 1442 QAI 1444 Score = 32.3 bits (72), Expect = 1.1 Identities = 28/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + + + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEDISKFAEKDNIVLGEGGVTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I V ++ + D VL + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILVTSKMEHLKKADKVLILHEGSCYFYGTFSELQSLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>MDR8_ARATH (Q9FWX7) Multidrug resistance protein 8 (P-glycoprotein 11)| Length = 1278 Score = 77.8 bits (190), Expect = 2e-14 Identities = 40/115 (34%), Positives = 70/115 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + QGLD+ V E G+ S GQ+Q + RA+L+ RIL+LDEAT+++D ++ V+Q+ Sbjct: 502 IDKLPQGLDTMVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEA 561 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + T + VAHR+ TV + DM+ + GK+VE ++L++ + +L+ Sbjct: 562 LDRVMVNRTTVIVAHRLSTVRNADMIAVIHRGKMVEKGSHSELLKDSEGAYSQLI 616 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/111 (33%), Positives = 65/111 (58%) Frame = -2 Query: 575 EQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSE 396 +QG D+ V E G S GQ+Q + RA+++ +IL+LDEAT+++D ++ V+Q + Sbjct: 1160 QQGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRV 1219 Query: 395 FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I VAHR+ T+ + D++ + +G + E L++ EG ++ LV Sbjct: 1220 MVNRTTIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLIKIEGGVYASLV 1270
>MDR17_ARATH (Q9M1Q9) Multidrug resistance protein 17 (P-glycoprotein 21)| Length = 1292 Score = 77.8 bits (190), Expect = 2e-14 Identities = 39/115 (33%), Positives = 69/115 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + QGLD+ V E G+ S GQ+Q + RA+L+ RIL+LDEAT+++D ++ ++Q+ Sbjct: 524 IDKLPQGLDTMVGEHGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERIVQEA 583 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + T + VAHR+ TV + DM+ + GK+VE ++L+ + +L+ Sbjct: 584 LDRIMVNRTTVVVAHRLSTVRNADMIAVIHQGKIVEKGSHSELLRDPEGAYSQLI 638 Score = 70.1 bits (170), Expect = 5e-12 Identities = 36/116 (31%), Positives = 67/116 (57%) Frame = -2 Query: 575 EQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSE 396 +QG D+ V E G S GQ+Q + RA+++ ++L+LDEAT+++D ++ V+Q + Sbjct: 1174 QQGYDTMVGERGVQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRV 1233 Query: 395 FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEYWS 228 T + VAHR+ T+ + D++ + +G +VE K L+ + ++ LV + S Sbjct: 1234 MVNRTTVVVAHRLSTIKNADVIAVVKNGVIVEKGKHETLINIKDGVYASLVQLHLS 1289
>MSBA_ACIAD (Q6F9X0) Lipid A export ATP-binding/permease protein msbA| Length = 574 Score = 77.8 bits (190), Expect = 2e-14 Identities = 37/106 (34%), Positives = 63/106 (59%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 QG D+ + G N S GQRQ + RA+L+ IL+LDEAT+++DN ++ +QK Sbjct: 460 QGYDTILGAQGLNLSGGQRQRIAIARAILKNAPILILDEATSALDNESEHFIQKAFDEAM 519 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 + T I +AHR+ T+ + D ++ M G+++E +L+ +G+ F Sbjct: 520 QNRTTIVIAHRLSTIENADRIVVMDKGQIIEQGTHQELLLKQGAYF 565
>LMRA_LACLA (Q9CHL8) Multidrug resistance ABC transporter ATP-binding and| permease protein (EC 3.6.3.44) Length = 590 Score = 77.4 bits (189), Expect = 3e-14 Identities = 43/117 (36%), Positives = 70/117 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 V+ L++ V E G S GQRQ + RA LR +IL+LDEATAS+D+ +++++QK Sbjct: 469 VENMPDQLNTEVGERGVKISGGQRQRLAIARAFLRNPKILMLDEATASLDSESESMVQKA 528 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 + S K T + +AHR+ T++D D + + G++ K +L+ T L+ K V+E Sbjct: 529 LDSLMKGRTTLVIAHRLSTIVDADKIYFIEKGQITGSGKHNELVATH-PLYAKYVSE 584
>MSBA_HAEIN (P44407) Lipid A export ATP-binding/permease protein msbA| Length = 587 Score = 77.4 bits (189), Expect = 3e-14 Identities = 38/112 (33%), Positives = 67/112 (59%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 LE +++ Q D+ + E+G++ S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 465 LEFIEKLPQVFDTVIGENGTSLSGGQRQRLAIARALLRNSPVLILDEATSALDTESERAI 524 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + K TV+ +AHR+ T+ + D +L + G++ E L+E G+ Sbjct: 525 QSALEELKKDRTVVVIAHRLSTIENADEILVIDHGEIRERGNHKTLLEQNGA 576
>MDR2_MOUSE (P21440) Multidrug resistance protein 2 (EC 3.6.3.44)| (P-glycoprotein 2) Length = 1276 Score = 77.4 bits (189), Expect = 3e-14 Identities = 40/116 (34%), Positives = 71/116 (61%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + Q D+ V + G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++A +Q Sbjct: 512 IMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAA 571 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ T+ + D++ DG +VE ++LM+ EG ++ +LVN Sbjct: 572 LDKAREGRTTIVIAHRLSTIRNADVIAGFEDGVIVEQGSHSELMKKEG-IYFRLVN 626 Score = 74.7 bits (182), Expect = 2e-13 Identities = 36/116 (31%), Positives = 73/116 (62%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++ Q ++ V + G+ S GQ+Q + RAL+R+ R+L+LDEAT+++D ++ V+Q+ Sbjct: 1154 IETLPQKYNTRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEA 1213 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ T+ + D+++ + +GKV E+ +L+ +G ++ +VN Sbjct: 1214 LDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKG-IYFSMVN 1268
>MSBA_PHOLL (Q7N6C6) Lipid A export ATP-binding/permease protein msbA| Length = 581 Score = 77.4 bits (189), Expect = 3e-14 Identities = 40/119 (33%), Positives = 70/119 (58%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ +++ + GLD+ + E+G S GQRQ + RALLR +L+LDEAT+++D ++ + Sbjct: 459 MDFIRKLDNGLDTMIGENGVLLSGGQRQRIAIARALLRDSPVLILDEATSALDTESERAI 518 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--SLFHKL 246 Q + K T + +AHR+ T+ + D +L + DG +VE L+E G S H++ Sbjct: 519 QAALDELQKNRTSLVIAHRLSTIENADEILVVEDGHIVERGDHLSLLERNGVYSQLHRM 577
>MSBA_BORPE (Q7VWD8) Lipid A export ATP-binding/permease protein msbA| Length = 623 Score = 77.0 bits (188), Expect = 4e-14 Identities = 40/125 (32%), Positives = 72/125 (57%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L LLE V G+ + V ++ + S GQRQ + RAL++ +L+LDEAT+++DN Sbjct: 494 LAAANLLEFVDGLPLGIHTPVGQNAARLSGGQRQRLAIARALIKNAPVLILDEATSALDN 553 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++ +Q ++ + T + +AHR+ TV + D ++ + GK+VE+ ++L+ G L+ Sbjct: 554 ESERQVQASLERLMRGRTTLVIAHRLSTVQNADRIIVLDAGKIVEHGPHSELLAANG-LY 612 Query: 254 HKLVN 240 L N Sbjct: 613 ASLYN 617
>MSBA_BORPA (Q7W9N7) Lipid A export ATP-binding/permease protein msbA| Length = 623 Score = 77.0 bits (188), Expect = 4e-14 Identities = 40/125 (32%), Positives = 72/125 (57%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L LLE V G+ + V ++ + S GQRQ + RAL++ +L+LDEAT+++DN Sbjct: 494 LAAANLLEFVDGLPLGIHTPVGQNAARLSGGQRQRLAIARALIKNAPVLILDEATSALDN 553 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++ +Q ++ + T + +AHR+ TV + D ++ + GK+VE+ ++L+ G L+ Sbjct: 554 ESERQVQASLERLMRGRTTLVIAHRLSTVQNADRIIVLDAGKIVEHGPHSELLAANG-LY 612 Query: 254 HKLVN 240 L N Sbjct: 613 ASLYN 617
>MSBA_BORBR (Q7WH20) Lipid A export ATP-binding/permease protein msbA| Length = 623 Score = 77.0 bits (188), Expect = 4e-14 Identities = 40/125 (32%), Positives = 72/125 (57%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L LLE V G+ + V ++ + S GQRQ + RAL++ +L+LDEAT+++DN Sbjct: 494 LAAANLLEFVDGLPLGIHTPVGQNAARLSGGQRQRLAIARALIKNAPVLILDEATSALDN 553 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++ +Q ++ + T + +AHR+ TV + D ++ + GK+VE+ ++L+ G L+ Sbjct: 554 ESERQVQASLERLMRGRTTLVIAHRLSTVQNADRIIVLDAGKIVEHGPHSELLAANG-LY 612 Query: 254 HKLVN 240 L N Sbjct: 613 ASLYN 617
>ABCB7_MOUSE (Q61102) ATP-binding cassette sub-family B member 7, mitochondrial| (ATP-binding cassette transporter 7) (ABC transporter 7 protein) (Fragment) Length = 694 Score = 77.0 bits (188), Expect = 4e-14 Identities = 42/128 (32%), Positives = 70/128 (54%) Frame = -2 Query: 599 LLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAV 420 L +A+ G D+ V E G S G++Q + RA+L+ +++ DEAT+S+D+ T+ Sbjct: 529 LHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKNPPVILYDEATSSLDSITEET 588 Query: 419 LQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + +R K+ T I +AHR+ TV+D D ++ +S GKV E L+ S++ + Sbjct: 589 ILGAMRDVVKHRTSIFIAHRLSTVVDADEIIVLSQGKVAERGTHYGLLANSSSIY----S 644 Query: 239 EYWSYTSN 216 E W SN Sbjct: 645 EMWHTQSN 652
>MSBA_SHEON (Q8EDF0) Lipid A export ATP-binding/permease protein msbA| Length = 601 Score = 77.0 bits (188), Expect = 4e-14 Identities = 39/117 (33%), Positives = 70/117 (59%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E +++ GLD+ V E+G S GQRQ + RA+LR +L+LDEAT+++D ++ + Sbjct: 479 MEFIEQLPDGLDTQVGENGVLLSGGQRQRIAIARAMLRDAPVLILDEATSALDTESEKAI 538 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 Q+ + + + T + +AHR+ T+ D +L + G++VE L+E G ++ KL Sbjct: 539 QQGLDNLRQNRTSVVIAHRLSTIESADQILVVDQGRIVERGTHKSLLEL-GGMYAKL 594
>CFTR_TRIVU (Q5D1Z7) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1478 Score = 77.0 bits (188), Expect = 4e-14 Identities = 40/124 (32%), Positives = 73/124 (58%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ LD +V+ G S G +QL CL R++L + +IL+LDE +A +D Sbjct: 1318 DEVGLKSVIEQFPGKLDFVLVDAGCVLSHGHKQLICLARSVLSKAKILLLDEPSAHLDPI 1377 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T ++++ +++ F CTVI HRI +++C L + + KV +Y+ KL+ TE L+ Sbjct: 1378 TYQIIRRALKNAFADCTVILSEHRIEAMLECQRFLVIEESKVRQYESIQKLV-TEKRLYG 1436 Query: 251 KLVN 240 + ++ Sbjct: 1437 QAIS 1440 Score = 33.5 bits (75), Expect = 0.51 Identities = 26/122 (21%), Positives = 51/122 (41%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + ++ + E G S GQR L RA+ + + +LD +D T+ Sbjct: 524 CQLEEEISKFAEKDNTILGEGGITLSGGQRARISLARAIYKDADLYLLDSPFGYLDVLTE 583 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + + + T I + ++ + D +L + +G Y ++L K Sbjct: 584 KEIFESCVCKLMANKTRILITSKMEHLKKADKILILHEGSCYFYGAFSELQSLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>MDR1_HUMAN (P08183) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1280 Score = 77.0 bits (188), Expect = 4e-14 Identities = 42/107 (39%), Positives = 67/107 (62%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYC 384 D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++AV+Q + K Sbjct: 521 DTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGR 580 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I +AHR+ TV + D++ DG +VE +LM+ +G ++ KLV Sbjct: 581 TTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKG-IYFKLV 626 Score = 68.9 bits (167), Expect = 1e-11 Identities = 33/100 (33%), Positives = 62/100 (62%) Frame = -2 Query: 554 VVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYCTVI 375 V + G+ S GQ+Q + RAL+R+ IL+LDEAT+++D ++ V+Q+ + + T I Sbjct: 1169 VGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCI 1228 Query: 374 TVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 +AHR+ T+ + D+++ +G+V E+ +L+ +G F Sbjct: 1229 VIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYF 1268
>MDR10_ARATH (Q9SGY1) Multidrug resistance protein 10 (P-glycoprotein 10)| Length = 1316 Score = 76.6 bits (187), Expect = 5e-14 Identities = 38/111 (34%), Positives = 66/111 (59%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G + V E G S GQRQ + RA+L+ IL+LDEAT+++D ++ V+Q+ + Sbjct: 1197 EGYSTKVGERGIQMSGGQRQRIAIARAVLKNPEILLLDEATSALDVESERVVQQALDRLM 1256 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + T + VAHR+ T+ + DM+ + DGK++E L+E + + KL++ Sbjct: 1257 RDRTTVVVAHRLSTIKNSDMISVIQDGKIIEQGSHNILVENKNGPYSKLIS 1307 Score = 62.8 bits (151), Expect = 8e-10 Identities = 35/122 (28%), Positives = 65/122 (53%) Frame = -2 Query: 554 VVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYCTVI 375 V E G S GQ+Q + RA+++ IL+LDEAT+++D ++ ++Q+ + T + Sbjct: 557 VGERGIQLSGGQKQRISISRAIVKNPSILLLDEATSALDAESEKIVQEALDRVMVGRTTV 616 Query: 374 TVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEYWSYTSNGNI*KSL 195 VAHR+ TV + D++ + GK++E +L+ + L+ + + N N SL Sbjct: 617 VVAHRLSTVRNADIIAVVGGGKIIESGSHDELISNPDGAYSSLLRIQEAASPNLNHTPSL 676 Query: 194 SI 189 + Sbjct: 677 PV 678
>ABCBA_MOUSE (Q9JI39) ATP-binding cassette sub-family B member 10, mitochondrial| precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein) Length = 715 Score = 76.6 bits (187), Expect = 5e-14 Identities = 41/127 (32%), Positives = 73/127 (57%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E ++ QG D+ V E G S GQ+Q + RALL+ +IL+LDEAT+++D + ++Q Sbjct: 579 EFIRSFPQGFDTVVGEKGILLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEHLVQ 638 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 + + + TV+ +AHR+ T+ + + V + GK+ E+ +L+ L+ KL+N+ Sbjct: 639 EALDRLMEGRTVLIIAHRLSTIKNANFVAVLDHGKICEHGTHEELLLKPNGLYRKLMNKQ 698 Query: 233 WSYTSNG 213 + NG Sbjct: 699 SFLSYNG 705
>Y1303_MYCBO (P63398) Hypothetical ABC transporter ATP-binding protein Mb1303c| Length = 631 Score = 76.3 bits (186), Expect = 7e-14 Identities = 36/102 (35%), Positives = 62/102 (60%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 G + V DG + S+G++QL + RA L R ++L+LDEAT+S+D T+ ++Q+ +R + Sbjct: 522 GYQTRVSGDGGSISVGEKQLITIARAFLARPQLLILDEATSSVDTRTELLIQRAMRELRR 581 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 T +AHR+ T+ D D +L + G++VE +L+ G Sbjct: 582 DRTSFIIAHRLSTIRDADHILVVQTGQIVERGNHAELLARRG 623
>Y1272_MYCTU (P63397) Hypothetical ABC transporter ATP-binding protein| Rv1272c/MT1310 Length = 631 Score = 76.3 bits (186), Expect = 7e-14 Identities = 36/102 (35%), Positives = 62/102 (60%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 G + V DG + S+G++QL + RA L R ++L+LDEAT+S+D T+ ++Q+ +R + Sbjct: 522 GYQTRVSGDGGSISVGEKQLITIARAFLARPQLLILDEATSSVDTRTELLIQRAMRELRR 581 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 T +AHR+ T+ D D +L + G++VE +L+ G Sbjct: 582 DRTSFIIAHRLSTIRDADHILVVQTGQIVERGNHAELLARRG 623
>LKTB_ACTAC (P23702) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 707 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 67/114 (58%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ RIL+ DEAT+++D ++ ++ Sbjct: 588 ISELREGYNTVVGEQGAGLSGGQRQRIAIARALVNNPRILIFDEATSALDYESENIIMHN 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + + TV+ +AHR+ TV + D ++ M G+++E K +L++ E L+ L Sbjct: 648 MHKICQNRTVLIIAHRLSTVKNADRIIVMDKGEIIEQGKHQELLKDEKGLYSYL 701
>MDR2_RAT (Q08201) Multidrug resistance protein 2 (EC 3.6.3.44)| (P-glycoprotein 2) (P-glycoprotein 3) Length = 1278 Score = 76.3 bits (186), Expect = 7e-14 Identities = 40/116 (34%), Positives = 71/116 (61%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + Q D+ V + G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++A +Q Sbjct: 512 IMKLPQKFDTLVGDRGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAA 571 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ TV + D++ DG +VE ++L++ EG ++ +LVN Sbjct: 572 LDKAREGRTTIVIAHRLSTVRNADVIAGFEDGVIVEQGSHSELIKKEG-IYFRLVN 626 Score = 75.1 bits (183), Expect = 2e-13 Identities = 36/116 (31%), Positives = 73/116 (62%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++ Q ++ V + G+ S GQ+Q + RAL+R+ R+L+LDEAT+++D ++ V+Q+ Sbjct: 1156 IETLPQKYETRVGDKGTQLSGGQKQRIAIARALIRQPRVLLLDEATSALDTESEKVVQEA 1215 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ T+ + D+++ + +GKV E+ +L+ +G ++ +VN Sbjct: 1216 LDKAREGRTCIVIAHRLSTIQNADLIVVIDNGKVKEHGTHQQLLAQKG-IYFSMVN 1270
>MSBA_PSEAE (Q9HUG8) Lipid A export ATP-binding/permease protein msbA| Length = 603 Score = 76.3 bits (186), Expect = 7e-14 Identities = 38/110 (34%), Positives = 62/110 (56%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + QG D+ V E+G S GQRQ + RALL+ +L+LDEAT+++D ++ +Q Sbjct: 475 EFIDNLPQGFDTEVGENGVLLSGGQRQRLAIARALLKDAPLLILDEATSALDTESERHIQ 534 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + K T + +AHR+ T+ D++L M G++VE +L+ G Sbjct: 535 AALDEVMKGRTTLVIAHRLSTIEKADLILVMDQGQIVERGSHAELLAQNG 584
>LKTB_PASTR (Q933E0) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKTB_MANGL (Q933I3) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKTB7_PASHA (P0C086) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKB2B_PASHA (Q93FG6) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKB2A_PASHA (Q93FH0) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKB1B_PASHA (Q93FH6) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKB1A_PASHA (P16532) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKB16_PASHA (Q93FH3) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYQSEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKB14_PASHA (P0C087) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>LKB13_PASHA (Q93FH2) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 76.3 bits (186), Expect = 7e-14 Identities = 37/114 (32%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHHELLQNSNGLYSYL 702
>CFTR_XENLA (P26363) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1485 Score = 76.3 bits (186), Expect = 7e-14 Identities = 39/109 (35%), Positives = 65/109 (59%) Frame = -2 Query: 566 LDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY 387 LD +++ G S G +QL CL R++L + +IL+LDE +A +D T +++KT++ F Sbjct: 1338 LDFVLLDGGCVLSHGHKQLVCLARSVLSKAKILLLDEPSAHLDPITFQIIRKTLKHAFAD 1397 Query: 386 CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 CTVI HR+ +++C L + D V +YD KL+ E S F + ++ Sbjct: 1398 CTVILSEHRLEAMLECQRFLVIEDNTVRQYDSIQKLV-NEKSFFKQAIS 1445 Score = 33.1 bits (74), Expect = 0.66 Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD 426 CQL E + + + ++ + E G S GQR L RA+ + + +LD + +D T+ Sbjct: 525 CQLEEDISKFPEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFSYLDLFTE 584 Query: 425 -AVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEY 297 + + + T I V ++ + D VL + +G Y Sbjct: 585 KEIFESCVCKLMANKTRILVTSKVEQLKKADKVLILHEGSCYFY 628
>LMRA_LACLC (P97046) Multidrug resistance ABC transporter ATP-binding and| permease protein (EC 3.6.3.44) Length = 590 Score = 76.3 bits (186), Expect = 7e-14 Identities = 42/117 (35%), Positives = 70/117 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 V+ L++ V E G S GQRQ + RA LR +IL+LDEATAS+D+ +++++Q+ Sbjct: 469 VENMPDQLNTEVGERGVKISGGQRQRLAIARAFLRNPKILMLDEATASLDSESESMVQRA 528 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 + S K T + +AHR+ T++D D + + G++ K +L+ T L+ K V+E Sbjct: 529 LDSLMKGRTTLVIAHRLSTIVDADKIYFIEKGEITGSGKHNELVATH-PLYAKYVSE 584
>MSBA_BURPS (Q63VX7) Lipid A export ATP-binding/permease protein msbA| Length = 596 Score = 75.9 bits (185), Expect = 9e-14 Identities = 40/121 (33%), Positives = 66/121 (54%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L L E V G+D+ V ++G S GQRQ + RA+ + IL+LDEAT+++D+ Sbjct: 465 LRAANLWETVTAMPDGIDTLVGDNGMRLSGGQRQRLAIARAIYKDAPILILDEATSALDS 524 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++ +Q + + K T + +AHR+ T+ D +L + GK+VE +L+E G Sbjct: 525 ESERHVQAALETLMKGRTTLVIAHRLSTIERADRILVLEGGKIVESGSHRELLEQGGLYA 584 Query: 254 H 252 H Sbjct: 585 H 585
>MSBA_BURMA (Q62IG3) Lipid A export ATP-binding/permease protein msbA| Length = 596 Score = 75.9 bits (185), Expect = 9e-14 Identities = 40/121 (33%), Positives = 66/121 (54%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L L E V G+D+ V ++G S GQRQ + RA+ + IL+LDEAT+++D+ Sbjct: 465 LRAANLWETVTAMPDGIDTLVGDNGMRLSGGQRQRLAIARAIYKDAPILILDEATSALDS 524 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++ +Q + + K T + +AHR+ T+ D +L + GK+VE +L+E G Sbjct: 525 ESERHVQAALETLMKGRTTLVIAHRLSTIERADRILVLEGGKIVESGSHRELLEQGGLYA 584 Query: 254 H 252 H Sbjct: 585 H 585
>CFTR_MOUSE (P26361) Cystic fibrosis transmembrane conductance regulator (CFTR)| (cAMP-dependent chloride channel) (ATP-binding cassette transporter sub-family C member 7) Length = 1476 Score = 75.9 bits (185), Expect = 9e-14 Identities = 39/124 (31%), Positives = 71/124 (57%) Frame = -2 Query: 611 DKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNA 432 D+ L +++ L+ +V+ G S G +QL CL R++L + +I++LDE +A +D Sbjct: 1316 DEVGLKSVIEQFPGQLNFTLVDGGYVLSHGHKQLMCLARSVLSKAKIILLDEPSAHLDPI 1375 Query: 431 TDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 T V+++ ++ F CTVI HRI ++DC L + + V +YD L+ +E S+F Sbjct: 1376 TYQVIRRVLKQAFAGCTVILCEHRIEAMLDCQRFLVIEESNVWQYDSLQALL-SEKSIFQ 1434 Query: 251 KLVN 240 + ++ Sbjct: 1435 QAIS 1438 Score = 30.8 bits (68), Expect = 3.3 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Frame = -2 Query: 605 CQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT- 429 CQL + + + + ++ + E G S GQR L RA+ + + +LD +D T Sbjct: 524 CQLQQDITKFAEQDNTVLGEGGVTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTE 583 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + V + + T I V ++ + D +L + G Y ++L K Sbjct: 584 EQVFESCVCKLMANKTRILVTSKMEHLRKADKILILHQGSSYFYGTFSELQSLRPDFSSK 643 Query: 248 LV 243 L+ Sbjct: 644 LM 645
>MSBA_COXBU (Q83D84) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 75.9 bits (185), Expect = 9e-14 Identities = 34/112 (30%), Positives = 66/112 (58%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 +E +++ +GLD+ + E+G S GQRQ + RAL + I +LDEAT+S+D ++ + Sbjct: 457 MEFIEQLPEGLDTVIGENGVRLSGGQRQRIAIARALFKNAPIHILDEATSSLDTHSERHI 516 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 Q + + CT + +AHR+ T+ D ++ + +G+++E +L+ G+ Sbjct: 517 QAALDNLMDQCTTLVIAHRLSTIERADWIMVLEEGRLIEKGTHQQLLTLNGA 568
>LKTB_PASSP (P55122) Leukotoxin translocation ATP-binding protein lktB (EC| 3.6.3.43) Length = 708 Score = 75.9 bits (185), Expect = 9e-14 Identities = 36/114 (31%), Positives = 68/114 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + +G ++ V E G+ S GQRQ + RAL+ +IL+ DEAT+++D ++ ++ + Sbjct: 589 ISDVREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHIIMQN 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 ++ + TVI +AHR+ TV + D ++ M G++VE K +L++ L+ L Sbjct: 649 MQKICQGRTVILIAHRLSTVKNADRIIVMEKGEIVEQGKHNELLQNNNGLYSYL 702
>MSBA_RALSO (Q8XXB6) Lipid A export ATP-binding/permease protein msbA| Length = 592 Score = 75.1 bits (183), Expect = 2e-13 Identities = 34/117 (29%), Positives = 70/117 (59%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L+ L + V G+D+++ ++GS S GQRQ + RA+ + IL+LDEAT+++D+ Sbjct: 463 LEAAYLTDVVDNLPDGVDTNIGDNGSKLSGGQRQRLAIARAVYKDAPILILDEATSALDS 522 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ++ +Q + + + T + +AHR+ T+ + D ++ + G++VE +L++ +G Sbjct: 523 ESERQVQAALEALMQGRTTLVIAHRLSTIENADRIVVLEHGQIVEAGTHRELLDRDG 579
>MDR3_ARATH (Q9SYI2) Putative multidrug resistance protein 3 (P-glycoprotein 3)| Length = 1229 Score = 75.1 bits (183), Expect = 2e-13 Identities = 38/115 (33%), Positives = 70/115 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + +GL++ V E G+ S GQ+Q + RA+L+ RIL+LDEAT+++D ++ V+Q+ Sbjct: 469 IDKLPRGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEA 528 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + T + VAHR+ TV + DM+ + GK+VE ++L++ + +L+ Sbjct: 529 LDRVMMSRTTVIVAHRLSTVRNADMIAVIHRGKIVEEGSHSELLKDHEGAYAQLI 583 Score = 73.6 bits (179), Expect = 4e-13 Identities = 39/119 (32%), Positives = 69/119 (57%) Frame = -2 Query: 575 EQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSE 396 +QG D+ V E G S GQ+Q + RA+++ +IL+LDEAT+++D ++ V+Q + Sbjct: 1111 QQGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRV 1170 Query: 395 FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEYWSYTS 219 T + VAHR+ T+ + D++ + +G +VE L+ EG ++ LV + S +S Sbjct: 1171 MVNRTTVVVAHRLSTIKNADVIAVVKNGVIVEKGTHETLINIEGGVYASLVQLHISASS 1229
>MSBA_SHIFL (Q83LP0) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 74.7 bits (182), Expect = 2e-13 Identities = 40/119 (33%), Positives = 68/119 (57%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + + GLD+ + E+G S GQRQ + RALLR IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--SLFHKL 246 Q + K T + +AHR+ T+ D ++ + DG +VE L+E G + HK+ Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKM 578
>MSBA_ECOLI (P60752) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 74.7 bits (182), Expect = 2e-13 Identities = 40/119 (33%), Positives = 68/119 (57%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + + GLD+ + E+G S GQRQ + RALLR IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--SLFHKL 246 Q + K T + +AHR+ T+ D ++ + DG +VE L+E G + HK+ Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKM 578
>MSBA_ECOL6 (Q8FJB1) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 74.7 bits (182), Expect = 2e-13 Identities = 40/119 (33%), Positives = 68/119 (57%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + + GLD+ + E+G S GQRQ + RALLR IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--SLFHKL 246 Q + K T + +AHR+ T+ D ++ + DG +VE L+E G + HK+ Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKM 578
>MSBA_ECO57 (P60753) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 74.7 bits (182), Expect = 2e-13 Identities = 40/119 (33%), Positives = 68/119 (57%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + + GLD+ + E+G S GQRQ + RALLR IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--SLFHKL 246 Q + K T + +AHR+ T+ D ++ + DG +VE L+E G + HK+ Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKM 578
>MSBA_DESPS (Q6AJW3) Lipid A export ATP-binding/permease protein msbA| Length = 572 Score = 74.7 bits (182), Expect = 2e-13 Identities = 37/111 (33%), Positives = 64/111 (57%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 L ++E G D+ + E G+ S GQRQ + RALL IL+LDEAT+++D ++ + Sbjct: 453 LTFIEELPNGFDTALGEGGAKLSGGQRQRISIARALLADAPILILDEATSALDTESEREV 512 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 QK + + + T +AHR+ T+ + ++ + GK+VE +L++ EG Sbjct: 513 QKALENLMQNRTTFVIAHRLSTIKNASRIVVVKKGKIVEEGSHEELLKLEG 563
>MAM1_SCHPO (P78966) Mating factor M secretion protein mam1 (Multiple drug| resistance protein homolog) (P-glycoprotein) Length = 1336 Score = 74.7 bits (182), Expect = 2e-13 Identities = 44/125 (35%), Positives = 71/125 (56%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LDK + E +Q GLD+ ++E N+S GQ Q RALLR R+L+LDE T+++D+ Sbjct: 1209 LDKTYMTEVIQNLPNGLDTPLLEFSKNFSGGQIQRLAFARALLRNPRLLILDECTSALDS 1268 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 + +L+KTI++ CTV+ + H+ + D ++ M G V E +LM + F Sbjct: 1269 KSSLLLEKTIQN--LSCTVLIITHQPSLMKLADRIIVMDSGIVKESGSFDELMNRH-THF 1325 Query: 254 HKLVN 240 KL++ Sbjct: 1326 WKLIH 1330 Score = 51.6 bits (122), Expect = 2e-06 Identities = 26/77 (33%), Positives = 45/77 (58%) Frame = -2 Query: 530 SMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYCTVITVAHRIPT 351 S GQ+Q L RALLR IL+LDE T+++D T ++ IR+ K T + + H + Sbjct: 572 SGGQQQRIALARALLRDTEILILDEPTSALDPITKNLVMDAIRAHRKGKTTLVITHDMSQ 631 Query: 350 VMDCDMVLAMSDGKVVE 300 + + ++VL + G +++ Sbjct: 632 INNDELVLVIDKGHLIQ 648
>MDR9_ARATH (Q9M0M2) Multidrug resistance protein 9 (P-glycoprotein 9)| Length = 1323 Score = 74.7 bits (182), Expect = 2e-13 Identities = 36/115 (31%), Positives = 68/115 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + QGLD+ V E G+ S GQ+Q + RA+L+ +IL+LDEAT+++D ++ ++Q Sbjct: 476 IDKLPQGLDTMVGEHGTQMSGGQKQRLAIARAILKNPKILLLDEATSALDAESERIVQDA 535 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + + T + VAHR+ T+ D++ + GK+VE ++++ + +LV Sbjct: 536 LVNLMSNRTTVVVAHRLTTIRTADVIAVVHQGKIVEKGTHDEMIQDPEGAYSQLV 590 Score = 65.5 bits (158), Expect = 1e-10 Identities = 34/100 (34%), Positives = 58/100 (58%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 QG D+ V E G S GQ+Q + RA+L+ +IL+LDEAT+++D ++ V+Q + Sbjct: 1162 QGYDTSVGERGVQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERVVQDALDRVM 1221 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLME 273 T + VAHR+ T+ + D++ + +G + E + L E Sbjct: 1222 VNRTTVVVAHRLTTIKNADVIAVVKNGVIAEKGRHETLDE 1261
>MSBA_PSEPK (Q88D92) Lipid A export ATP-binding/permease protein msbA| Length = 602 Score = 74.7 bits (182), Expect = 2e-13 Identities = 38/110 (34%), Positives = 62/110 (56%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E V +G D+ V E+G S GQRQ + RALL+ +L+LDEAT+++D ++ +Q Sbjct: 474 EFVDRLPKGFDTEVGENGVLLSGGQRQRLAIARALLKNAPLLILDEATSALDTESERHIQ 533 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + T + +AHR+ T+ D +L M G++VE T+L+ G Sbjct: 534 AALDHVMQGRTTLVIAHRLSTIEKADQILVMDQGRLVERGTHTELLAANG 583
>ABCBB_MOUSE (Q9QY30) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 74.3 bits (181), Expect = 3e-13 Identities = 40/122 (32%), Positives = 73/122 (59%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT 429 + QL + V + +++V GS S G++Q + RA++R +IL+LDEAT+++D + Sbjct: 1194 QAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTES 1253 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + +Q + + T I +AHR+ T+ + D++ MS G V+E KLM+ +G+ ++K Sbjct: 1254 EKTVQLALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGVVIEKGTHKKLMDQKGA-YYK 1312 Query: 248 LV 243 LV Sbjct: 1313 LV 1314 Score = 72.8 bits (177), Expect = 8e-13 Identities = 39/106 (36%), Positives = 62/106 (58%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 Q D+ V E G S GQ+Q + RAL+R+ +IL+LD AT+++DN ++A +Q + Sbjct: 546 QQFDTLVGEGGGQMSGGQKQRVAIARALIRKPKILLLDMATSALDNESEAKVQGALNKIQ 605 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+I+VAHR+ TV D+++ G VE +L+E +G F Sbjct: 606 HGHTIISVAHRLSTVRSADVIIGFEHGTAVERGTHEELLERKGVYF 651
>MSBA_XYLFT (Q87EF0) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 74.3 bits (181), Expect = 3e-13 Identities = 37/108 (34%), Positives = 60/108 (55%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 V + +GL V G S GQRQ + RA+L+ IL+LDEATA++DN ++ ++Q Sbjct: 467 VNQLPEGLQFQVGVKGGRLSGGQRQRLAIARAMLKDAPILILDEATAALDNESERLVQDA 526 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ++ T + +AHR+ T+ D VL M G+++E L+ +G Sbjct: 527 LQRLMPERTTLVIAHRLSTIKHADQVLVMDQGRIIESGTHVDLLARDG 574
>MSBA_XYLFA (Q9PEE7) Lipid A export ATP-binding/permease protein msbA| Length = 589 Score = 74.3 bits (181), Expect = 3e-13 Identities = 37/108 (34%), Positives = 60/108 (55%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 V + +GL V G S GQRQ + RA+L+ IL+LDEATA++DN ++ ++Q Sbjct: 467 VNQLPEGLQFQVGVKGGRLSGGQRQRLAIARAMLKDAPILILDEATAALDNESERLVQDA 526 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ++ T + +AHR+ T+ D VL M G+++E L+ +G Sbjct: 527 LQRLMPERTTLVIAHRLSTIKHADQVLVMDQGRIIESGTHVDLLARDG 574
>YWJA_BACSU (P45861) Hypothetical ABC transporter ATP-binding protein ywjA| Length = 575 Score = 74.3 bits (181), Expect = 3e-13 Identities = 39/121 (32%), Positives = 68/121 (56%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT 429 + L E V GLD+ + E G S GQ+Q + R L+ IL+LDEAT+++D T Sbjct: 445 QAHLEELVHNMPDGLDTMIGERGVKLSGGQKQRLSIARMFLKNPSILILDEATSALDTET 504 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 +A +QK ++ + T + +AHR+ T+ D D ++ +++ + E + L+E G L+ + Sbjct: 505 EAAIQKALQELSEGRTTLVIAHRLATIKDADRIVVVTNNGIEEQGRHQDLIEA-GGLYSR 563 Query: 248 L 246 L Sbjct: 564 L 564
>TAP2_RAT (P36372) Antigen peptide transporter 2 (APT2)| Length = 703 Score = 74.3 bits (181), Expect = 3e-13 Identities = 38/99 (38%), Positives = 66/99 (66%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E G+++ + E GS ++GQ+Q + RAL+R R+L+LDEAT+++D + LQ T Sbjct: 589 IGEMTNGINTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSALDAECEQALQ-T 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDK 291 RS+ + T++ +AHR+ TV + D VL + G++VE+D+ Sbjct: 648 WRSQ-EDRTMLVIAHRLHTVQNADQVLVLKQGQLVEHDQ 685
>ABCB7_RAT (Q704E8) ATP-binding cassette sub-family B member 7, mitochondrial| precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein) Length = 752 Score = 74.3 bits (181), Expect = 3e-13 Identities = 38/118 (32%), Positives = 67/118 (56%) Frame = -2 Query: 599 LLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAV 420 L +A+ G D+ V E G S G++Q + RA+L+ +++ DEAT+S+D+ T+ Sbjct: 587 LHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEET 646 Query: 419 LQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + +R K+ T I +AHR+ TV+D D ++ +S GKV E L+ S++ ++ Sbjct: 647 ILGAMRDVVKHRTSIFIAHRLSTVVDADEIIVLSQGKVAERGTHYGLLANSSSIYSEM 704
>MDR1_LEIEN (Q06034) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) Length = 1280 Score = 74.3 bits (181), Expect = 3e-13 Identities = 39/104 (37%), Positives = 64/104 (61%), Gaps = 2/104 (1%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRS-EF 393 G D+ V G S GQ+Q + R LLRR R+L+LDEAT+++D+ T+A +Q+ I + + Sbjct: 1163 GYDTEVGYKGRALSGGQKQRIAIARGLLRRPRLLLLDEATSALDSVTEAKVQEGIEAFQA 1222 Query: 392 KY-CTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 KY T +++AHR+ T+ CD ++ + G ++E +LM G Sbjct: 1223 KYKVTTVSIAHRLTTIRHCDQIILLDSGCIIEQGSHEELMALGG 1266 Score = 53.5 bits (127), Expect = 5e-07 Identities = 35/107 (32%), Positives = 60/107 (56%), Gaps = 7/107 (6%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKY- 387 D+ V GS S GQ+Q + RAL++R IL+LDEAT+++D ++ +Q + + Sbjct: 520 DTPVGPVGSLLSGGQKQRIAIARALVKRPPILLLDEATSALDRKSEMEVQAALDQLIQRG 579 Query: 386 -CTVITVAHRIPTVMDCDMVLAMS-DG----KVVEYDKPTKLMETEG 264 TV+ +AHR+ T+ D D + + DG ++ E +L+E +G Sbjct: 580 GTTVVVIAHRLATIRDMDRIYYVKHDGAEGSRITESGTFDELLELDG 626
>MSBA_METCA (Q60AA3) Lipid A export ATP-binding/permease protein msbA| Length = 601 Score = 73.9 bits (180), Expect = 3e-13 Identities = 36/111 (32%), Positives = 63/111 (56%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 L+ ++ QG D+ V + G S GQRQ + RALL+ IL+LDEAT+++D ++ + Sbjct: 465 LDFIETLPQGFDTLVGQQGIVLSGGQRQRIAIARALLKNAPILILDEATSALDAESERYV 524 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 Q+ + + T + +AHR+ T+ + D + M G+++E +LM G Sbjct: 525 QQALEVLMQNRTTLVIAHRLSTIQNADQICVMRGGRIIECGTHAQLMAARG 575
>NDVA_RHIME (P18767) Beta-(1-->2)glucan export ATP-binding protein ndvA| Length = 616 Score = 73.9 bits (180), Expect = 3e-13 Identities = 40/108 (37%), Positives = 66/108 (61%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++++ G D+ V E G+ S G+RQ + RA+L+ ILVLDEAT+++D T+A ++ Sbjct: 485 IEDRLNGYDTVVGERGNRLSGGERQRVAIARAILKNAPILVLDEATSALDVETEARVKDA 544 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 I + K T +AHR+ TV + D+V+ M G+VVE +L ++ G Sbjct: 545 IDALRKDRTTFIIAHRLSTVREADLVIFMDQGRVVEMGGFHELSQSNG 592
>MDR19_ARATH (Q9LSJ6) Putative multidrug resistance protein 19 (P-glycoprotein 17)| Length = 1240 Score = 73.9 bits (180), Expect = 3e-13 Identities = 37/123 (30%), Positives = 70/123 (56%), Gaps = 9/123 (7%) Frame = -2 Query: 614 LDKCQLLEA---------VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVL 462 +D+ +++EA + G D++ + G S GQ+Q + RA+L+ +L+L Sbjct: 1100 IDESEIIEAAKAANAHDFITSLSNGYDTNCGDKGVQLSGGQKQRIAIARAVLKNPSVLLL 1159 Query: 461 DEATASIDNATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTK 282 DEAT+++D+ ++ V+Q + T I +AHR+ T+ +CDM++ + GK+VE + Sbjct: 1160 DEATSALDSKSERVVQDALERVMVGRTSIMIAHRLSTIQNCDMIVVLGKGKIVESGTHSS 1219 Query: 281 LME 273 L+E Sbjct: 1220 LLE 1222 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/143 (27%), Positives = 80/143 (55%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 G + V E G S GQ+Q + RA+++ +IL+LDEAT+++D+ ++ V+Q+++ + Sbjct: 486 GYKTQVGERGVQMSGGQKQRIAIARAIIKSPKILLLDEATSALDSESERVVQESLDNASI 545 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEYWSYTSNGN 210 T I +AHR+ T+ + D++ + +G++VE +L++ + LV+ N Sbjct: 546 GRTTIVIAHRLSTIRNADVICVIHNGQIVETGSHEELLKRIDGQYTSLVSLQQMENEESN 605 Query: 209 I*KSLSILIAYWLQLSKR*KISR 141 + ++S+ + LSK K S+ Sbjct: 606 VNINVSVTKDQVMSLSKDFKYSQ 628
>MSBA_SALTY (P63359) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/119 (32%), Positives = 69/119 (57%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + + GLD+ + E+G S GQRQ + RALLR IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMDNGLDTIIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--SLFHKL 246 Q + K T + +AHR+ T+ D ++ + DG +VE ++L+ G + HK+ Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEQADEIVVVEDGIIVERGTHSELLAQHGVYAQLHKM 578
>MSBA_SALTI (P63360) Lipid A export ATP-binding/permease protein msbA| Length = 582 Score = 73.9 bits (180), Expect = 3e-13 Identities = 39/119 (32%), Positives = 69/119 (57%), Gaps = 2/119 (1%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 ++ + + + GLD+ + E+G S GQRQ + RALLR IL+LDEAT+++D ++ + Sbjct: 460 MDFINKMDNGLDTIIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--SLFHKL 246 Q + K T + +AHR+ T+ D ++ + DG +VE ++L+ G + HK+ Sbjct: 520 QAALDELQKNRTSLVIAHRLSTIEQADEIVVVEDGIIVERGTHSELLAQHGVYAQLHKM 578
>ABCB9_HUMAN (Q9NP78) ATP-binding cassette sub-family B member 9 precursor| (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9) Length = 766 Score = 73.6 bits (179), Expect = 4e-13 Identities = 37/115 (32%), Positives = 68/115 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E + G + E G+ S GQ+Q + RAL+R +L+LDEAT+++D ++ ++Q+ Sbjct: 625 IMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQA 684 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 I + TV+ +AHR+ TV +++ + G+VV+ +L+ +G L+ KLV Sbjct: 685 IHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLL-AQGGLYAKLV 738
>MDR12_ARATH (Q9C7F2) Multidrug resistance protein 12 (P-glycoprotein 14)| Length = 1247 Score = 73.6 bits (179), Expect = 4e-13 Identities = 38/118 (32%), Positives = 65/118 (55%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + E+G +HV + G S GQ+Q + RA+L+ +L+LDEAT+++D + + +Q Sbjct: 1125 EFISRMEEGYMTHVGDKGVQLSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSAEKQVQ 1184 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + K T I VAHR+ T+ D ++ + GKVVE +L+ + KL + Sbjct: 1185 EALDKLMKGRTTILVAHRLSTIRKADTIVVLHKGKVVEKGSHRELVSKSDGFYKKLTS 1242 Score = 72.0 bits (175), Expect = 1e-12 Identities = 37/116 (31%), Positives = 71/116 (61%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++ G ++ V E G+ S GQ+Q + RA+LR +IL+LDEAT+++D ++ ++Q+ Sbjct: 493 IKSLPNGYNTQVGEGGTQLSGGQKQRIAIARAVLRNPKILLLDEATSALDAESEKIVQQA 552 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + + T I +AHR+ T+ + D ++ + DG+V E ++L+ + G + LVN Sbjct: 553 LDNVMEKRTTIVIAHRLSTIRNVDKIVVLRDGQVRETGSHSELI-SRGGDYATLVN 607
>MDR1_RAT (P43245) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1277 Score = 73.6 bits (179), Expect = 4e-13 Identities = 40/107 (37%), Positives = 66/107 (61%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYC 384 D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++AV+Q + + Sbjct: 520 DTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGR 579 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I +AHR+ TV + D++ G +VE +LM+ +G ++ KLV Sbjct: 580 TTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKG-IYFKLV 625 Score = 71.2 bits (173), Expect = 2e-12 Identities = 35/116 (30%), Positives = 72/116 (62%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 Q ++++ EK ++ V + G+ S GQ+Q + RAL+R+ IL+LDEAT+++D ++ Sbjct: 1155 QFIDSLPEK---YNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEK 1211 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 V+Q+ + + T + +AHR+ T+ + D+++ + +G+V E+ +L+ +G F Sbjct: 1212 VVQEALDKAREGRTCVVIAHRLSTIQNADLIVVIQNGQVKEHGTHQQLLAQKGIYF 1267
>MDR7_ARATH (Q9FHF1) Multidrug resistance protein 7 (P-glycoprotein 7)| Length = 1248 Score = 73.2 bits (178), Expect = 6e-13 Identities = 38/110 (34%), Positives = 62/110 (56%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 QG ++ V E G S GQ+Q + RA+L+ +IL+LDEAT+++D ++ V+Q + Sbjct: 1132 QGYETSVGERGVQLSGGQKQRIAIARAILKDPKILLLDEATSALDAESERVVQDALDQVM 1191 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T + VAH + T+ D DM+ + +G + E + LME G + LV Sbjct: 1192 VNRTTVVVAHLLTTIKDADMIAVVKNGVIAESGRHETLMEISGGAYASLV 1241 Score = 73.2 bits (178), Expect = 6e-13 Identities = 36/115 (31%), Positives = 67/115 (58%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + QGL++ V E G+ S GQ+Q + RA+L+ +IL+LDEAT+++D ++ ++Q Sbjct: 478 IDKLPQGLETMVGEHGTQLSGGQKQRIAIARAILKNPKILLLDEATSALDAESERIVQDA 537 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + T + VAHR+ T+ DM+ + GKV+E ++++ + +LV Sbjct: 538 LVKLMLSRTTVVVAHRLTTIRTADMIAVVQQGKVIEKGTHDEMIKDPEGTYSQLV 592
>HMT1_SCHPO (Q02592) Heavy metal tolerance protein precursor| Length = 830 Score = 73.2 bits (178), Expect = 6e-13 Identities = 36/119 (30%), Positives = 70/119 (58%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 Q+ + + + G +S V E G S G++Q + RA+L+ I++LDEAT+++D T+ Sbjct: 698 QIHDRILQFPDGYNSRVGERGLKLSGGEKQRVAVARAILKDPSIILLDEATSALDTNTER 757 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 +Q + T I +AHR+ T+ + D++L +S+G++VE +L++ +G + K+ Sbjct: 758 QIQAALNRLASGRTAIVIAHRLSTITNADLILCISNGRIVETGTHEELIKRDGGAYKKM 816
>ABCBB_RABIT (Q9N0V3) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 73.2 bits (178), Expect = 6e-13 Identities = 39/122 (31%), Positives = 72/122 (59%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT 429 K Q+ + V + +++V GS S G++Q + RA++R +IL+LDEAT+++D + Sbjct: 1194 KAQVHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTES 1253 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + +Q + + T I +AHR+ T+ + D++ MS G V+E +LM +G+ ++K Sbjct: 1254 EKTVQVALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGMVIEKGTHEELMVQKGA-YYK 1312 Query: 248 LV 243 LV Sbjct: 1313 LV 1314 Score = 72.4 bits (176), Expect = 1e-12 Identities = 37/111 (33%), Positives = 64/111 (57%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + Q D+ V E G S GQ+Q + RAL+R +IL+LD AT+++DN ++A++Q+ Sbjct: 541 IMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEA 600 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 + T+++VAHR T+ D+++ G VE +L+E +G F Sbjct: 601 LSKTQHGHTIVSVAHRPATIRTADVIIGCEHGAAVERGTEEELLERKGVYF 651
>ABCBB_HUMAN (O95342) Bile salt export pump (ATP-binding cassette sub-family B| member 11) Length = 1321 Score = 73.2 bits (178), Expect = 6e-13 Identities = 39/111 (35%), Positives = 64/111 (57%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + Q D+ V E G S GQ+Q + RAL+R +IL+LD AT+++DN ++A++Q+ Sbjct: 541 IMDLPQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEV 600 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 + T+I+VAHR+ TV D ++ G VE +L+E +G F Sbjct: 601 LSKIQHGHTIISVAHRLSTVRAADTIIGFEHGTAVERGTHEELLERKGVYF 651 Score = 72.0 bits (175), Expect = 1e-12 Identities = 38/122 (31%), Positives = 72/122 (59%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT 429 + QL + V + +++V GS S G++Q + RA++R +IL+LDEAT+++D + Sbjct: 1194 QAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTES 1253 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + +Q + + T I +AHR+ T+ + D++ M+ G V+E +LM +G+ ++K Sbjct: 1254 EKTVQVALDKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHEELMAQKGA-YYK 1312 Query: 248 LV 243 LV Sbjct: 1313 LV 1314
>ABCB9_RAT (Q9QYJ4) ATP-binding cassette sub-family B member 9 precursor| (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) Length = 762 Score = 73.2 bits (178), Expect = 6e-13 Identities = 37/115 (32%), Positives = 68/115 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E + G + E G+ S GQ+Q + RAL+R +L+LDEAT+++D ++ ++Q+ Sbjct: 621 IMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQA 680 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 I + TV+ +AHR+ TV +++ + G+VV+ +L+ +G L+ KLV Sbjct: 681 IHGNLQRHTVLIIAHRLSTVERAHLIVVLDKGRVVQQGTHQQLL-AQGGLYAKLV 734
>ABCB9_MOUSE (Q9JJ59) ATP-binding cassette sub-family B member 9 precursor| (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9) Length = 762 Score = 73.2 bits (178), Expect = 6e-13 Identities = 37/115 (32%), Positives = 68/115 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E + G + E G+ S GQ+Q + RAL+R +L+LDEAT+++D ++ ++Q+ Sbjct: 621 IMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQA 680 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 I + TV+ +AHR+ TV +++ + G+VV+ +L+ +G L+ KLV Sbjct: 681 IHGNLQRHTVLIIAHRLSTVERAHLIVVLDKGRVVQQGTHQQLL-AQGGLYAKLV 734
>MDR3_MOUSE (P21447) Multidrug resistance protein 3 (EC 3.6.3.44)| (P-glycoprotein 3) (MDR1A) Length = 1276 Score = 73.2 bits (178), Expect = 6e-13 Identities = 40/107 (37%), Positives = 65/107 (60%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYC 384 D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++AV+Q + + Sbjct: 517 DTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGR 576 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I +AHR+ TV + D++ G +VE +LM +G ++ KLV Sbjct: 577 TTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKG-IYFKLV 622 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/116 (31%), Positives = 72/116 (62%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 Q ++++ +K ++ V + G+ S GQ+Q + RAL+R+ IL+LDEAT+++D ++ Sbjct: 1152 QFIDSLPDK---YNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEK 1208 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 V+Q+ + + T I +AHR+ T+ + D+++ + +GKV E+ +L+ +G F Sbjct: 1209 VVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYF 1264
>MDR2_CRIGR (P21449) Multidrug resistance protein 2 (EC 3.6.3.44) (P-glycoprotein| 2) Length = 1276 Score = 73.2 bits (178), Expect = 6e-13 Identities = 37/116 (31%), Positives = 72/116 (62%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 Q +E++ +K ++ V + G+ S GQ+Q + RAL+R+ IL+LDEAT+++D ++ Sbjct: 1154 QFIESLPDK---YNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEK 1210 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 V+Q+ + + T I +AHR+ T+ + D+++ + +GKV E+ +L+ +G F Sbjct: 1211 VVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYF 1266 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/100 (37%), Positives = 61/100 (61%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYC 384 D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++AV+Q + + Sbjct: 520 DTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGR 579 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 T I +AHR+ TV + D++ G +VE +LM+ +G Sbjct: 580 TTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHEELMKEKG 619
>MDR1_MOUSE (P06795) Multidrug resistance protein 1 (EC 3.6.3.44)| (P-glycoprotein 1) (CD243 antigen) Length = 1276 Score = 73.2 bits (178), Expect = 6e-13 Identities = 40/107 (37%), Positives = 65/107 (60%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYC 384 D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++AV+Q + + Sbjct: 520 DTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGR 579 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I +AHR+ TV + D++ G +VE +LM +G ++ KLV Sbjct: 580 TTIVIAHRLSTVRNADVIAGFDGGVIVEQGNHDELMREKG-IYFKLV 625 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/116 (31%), Positives = 72/116 (62%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 Q ++++ +K ++ V + G+ S GQ+Q + RAL+R+ IL+LDEAT+++D ++ Sbjct: 1154 QFIDSLPDK---YNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEK 1210 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 V+Q+ + + T I +AHR+ T+ + D+++ + +GKV E+ +L+ +G F Sbjct: 1211 VVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIENGKVKEHGTHQQLLAQKGIYF 1266
>MDR1_CRIGR (P21448) Multidrug resistance protein 1 (EC 3.6.3.44) (P-glycoprotein| 1) (CD243 antigen) Length = 1276 Score = 73.2 bits (178), Expect = 6e-13 Identities = 37/116 (31%), Positives = 72/116 (62%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 Q +E++ +K ++ V + G+ S GQ+Q + RAL+R+ IL+LDEAT+++D ++ Sbjct: 1153 QFIESLPDK---YNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEK 1209 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 V+Q+ + + T I +AHR+ T+ + D+++ + +GKV E+ +L+ +G F Sbjct: 1210 VVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQKGIYF 1265 Score = 73.2 bits (178), Expect = 6e-13 Identities = 40/107 (37%), Positives = 65/107 (60%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYC 384 D+ V E G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++AV+Q + + Sbjct: 518 DTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQAALDKAREGR 577 Query: 383 TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I +AHR+ TV + D++ G +VE +LM +G ++ KLV Sbjct: 578 TTIVIAHRLSTVRNADIIAGFDGGVIVEQGNHEELMREKG-IYFKLV 623
>Y015_MYCGE (P47261) Hypothetical ABC transporter ATP-binding protein MG015| Length = 589 Score = 73.2 bits (178), Expect = 6e-13 Identities = 33/103 (32%), Positives = 64/103 (62%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G D+++ S+G+RQL + RA++R +L+LDEAT+S+D ++ ++Q++I Sbjct: 476 KGYDTYISNKADYLSVGERQLLTIARAVIRNAPVLLLDEATSSVDVHSEKLIQESIGRLM 535 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 K T ++HR+ + D +++ ++DGKV+E +LM+ G Sbjct: 536 KNKTSFIISHRLSIIRDATLIMVINDGKVLEMGNHDQLMKQNG 578
>MDR15_ARATH (Q9C7F8) Putative multidrug resistance protein 15 (P-glycoprotein| 13) Length = 1245 Score = 73.2 bits (178), Expect = 6e-13 Identities = 39/116 (33%), Positives = 70/116 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++ G ++ V E G+ S GQ+Q + RA+LR +IL+LDEAT+++D ++ ++Q+ Sbjct: 492 IKSLPNGYNTQVGEGGTQLSGGQKQRIAIARAVLRNPKILLLDEATSALDAESEKIVQQA 551 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + + T I VAHR+ T+ + D ++ + DG+V E ++LM G + LVN Sbjct: 552 LDNVMEKRTTIVVAHRLSTIRNVDKIVVLRDGQVRETGSHSELM-LRGGDYATLVN 606 Score = 70.1 bits (170), Expect = 5e-12 Identities = 35/118 (29%), Positives = 66/118 (55%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + + E+G +H + G S GQ+Q + RA+L+ +L+LDEAT+++D +++ ++Q Sbjct: 1123 EFIIKMEEGYKTHAGDKGVQLSGGQKQRVAIARAVLKDPSVLLLDEATSALDTSSEKLVQ 1182 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + K T + VAHR+ T+ D V + G+VVE +L+ + +L + Sbjct: 1183 EALDKLMKGRTTVLVAHRLSTIRKADTVAVLHKGRVVEKGSHRELVSIPNGFYKQLTS 1240
>MSBA_LEGPH (Q5ZUH9) Lipid A export ATP-binding/permease protein msbA| Length = 588 Score = 72.8 bits (177), Expect = 8e-13 Identities = 34/110 (30%), Positives = 64/110 (58%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E +++ G D+ V E+G S GQRQ + RA+L+ IL+LDEAT+++D+ ++ +Q Sbjct: 459 EFIKQLPDGYDTRVGENGVLLSGGQRQRIAIARAILKDAPILILDEATSALDSESEHYIQ 518 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + K T + +AHR+ T+ ++ + G++VE +L++ +G Sbjct: 519 AALEQVMKGRTTLIIAHRLSTIKHAHKIIVLQHGRIVEQGSHQELLDMDG 568
>MSBA_LEGPA (Q5X498) Lipid A export ATP-binding/permease protein msbA| Length = 588 Score = 72.8 bits (177), Expect = 8e-13 Identities = 34/110 (30%), Positives = 64/110 (58%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E +++ G D+ V E+G S GQRQ + RA+L+ IL+LDEAT+++D+ ++ +Q Sbjct: 459 EFIKQLPDGYDTRVGENGVLLSGGQRQRIAIARAILKDAPILILDEATSALDSESEHYIQ 518 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + K T + +AHR+ T+ ++ + G++VE +L++ +G Sbjct: 519 AALEQVMKGRTTLIIAHRLSTIKHAHKIIVLQHGRIVEQGSHQELLDMDG 568
>MDR49_DROME (Q00449) Multidrug resistance protein homolog 49 (EC 3.6.3.44)| (P-glycoprotein 49) Length = 1302 Score = 72.8 bits (177), Expect = 8e-13 Identities = 39/111 (35%), Positives = 68/111 (61%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G D+ V E G+ S GQ+Q + RAL+R+ ++L+LDEAT+++D ++ +Q + Sbjct: 528 KGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELAS 587 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + T + VAHR+ T+ + D ++ + DG V E +LME G L+ +LV+ Sbjct: 588 QGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMERRG-LYCELVS 637 Score = 66.6 bits (161), Expect = 5e-11 Identities = 36/99 (36%), Positives = 61/99 (61%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 QG D+ + + S S GQ+Q + RAL+R +IL+LDEAT+++D ++ V+Q+ + Sbjct: 1188 QGYDTRLGKT-SQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDEAR 1246 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLM 276 T +T+AHR+ TV + D++ + G VVE+ +LM Sbjct: 1247 SGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGTHDELM 1285
>Y742_STRCO (Q9ZNB0) Hypothetical ABC transporter ATP-binding protein SCO0742| Length = 584 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/94 (40%), Positives = 57/94 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 V+ GL++ V G+ S G+RQ + RALLRR R+L+LDEAT+ +D +A L+ T Sbjct: 462 VERLPNGLETLVGHRGTKLSGGERQRVAIARALLRRPRLLLLDEATSQLDAVNEAALRDT 521 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKV 306 + + TV+ VAHR+ TV D ++ M G+V Sbjct: 522 VADVARTTTVLVVAHRLSTVTMADRIVVMDAGRV 555
>ABCBB_RAT (O70127) Bile salt export pump (ATP-binding cassette sub-family B| member 11) (Sister of P-glycoprotein) Length = 1321 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/122 (31%), Positives = 72/122 (59%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT 429 + QL + V + +++V GS S G++Q + RA++R +IL+LDEAT+++D + Sbjct: 1194 QAQLHDFVMSLPEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTES 1253 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + +Q + + T I +AHR+ T+ + D++ +S G V+E KLM +G+ ++K Sbjct: 1254 EKTVQTALDKAREGRTCIVIAHRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGA-YYK 1312 Query: 248 LV 243 LV Sbjct: 1313 LV 1314 Score = 71.6 bits (174), Expect = 2e-12 Identities = 39/106 (36%), Positives = 62/106 (58%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 Q D+ V E G S GQ+Q + RAL+R +IL+LD AT+++DN ++A +Q+ + Sbjct: 546 QQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEARVQEALNKIQ 605 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+I+VAHR+ TV D+++ G VE +L+E +G F Sbjct: 606 HGHTIISVAHRLSTVRAADVIIGFEHGVAVERGTHEELLERKGVYF 651
>MSBA_LEGPL (Q5WVN2) Lipid A export ATP-binding/permease protein msbA| Length = 588 Score = 72.0 bits (175), Expect = 1e-12 Identities = 34/110 (30%), Positives = 63/110 (57%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E +++ G D+ V E+G S GQRQ + RA+L+ IL+LDEAT+++D+ ++ +Q Sbjct: 459 EFIKQLPDGYDTRVGENGVLLSGGQRQRIAIARAILKDAPILILDEATSALDSESEHYIQ 518 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + T + +AHR+ T+ ++ M G++VE +L++ +G Sbjct: 519 AALEQVMNGRTTLIIAHRLSTIKHAHKIIVMQHGRIVEQGSHQELLDMDG 568
>MDR5_ARATH (Q9SYI3) Putative multidrug resistance protein 5 (P-glycoprotein 5)| Length = 1230 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/109 (33%), Positives = 67/109 (61%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 GL++ V E G+ S GQ+Q + RA+L+ RIL+LDEAT+++D ++ V+Q+ + Sbjct: 480 GLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRIMV 539 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T + VAHR+ TV + D++ + GK+VE ++L++ + +L+ Sbjct: 540 NRTTVIVAHRLSTVRNADIIAVIHRGKIVEEGSHSELLKDHEGAYSQLL 588 Score = 69.7 bits (169), Expect = 6e-12 Identities = 36/111 (32%), Positives = 64/111 (57%) Frame = -2 Query: 575 EQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSE 396 ++G D+ V E G S GQ+Q + RA+++ +IL+LDEAT+++D ++ V+Q + Sbjct: 1112 QKGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRV 1171 Query: 395 FKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I VAHR+ T+ + D++ + +G + E L+ EG ++ LV Sbjct: 1172 MVNRTTIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLINIEGGVYASLV 1222
>CYAB_BORPE (P18770) Cyclolysin secretion/processing ATP-binding protein cyaB| (EC 3.4.22.-) Length = 712 Score = 71.6 bits (174), Expect = 2e-12 Identities = 40/116 (34%), Positives = 67/116 (57%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + + +G D+ + E+G S GQRQ + RAL+ R R+L+LDEAT+++D ++ ++Q Sbjct: 589 EFICQLPEGYDTMLGENGVGLSGGQRQRIGIARALIHRPRVLILDEATSALDYESEHIIQ 648 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 + +R TVI +AHR+ V D ++ M G+V E L+ G L+ +L Sbjct: 649 RNMRDICDGRTVIIIAHRLSAVRCADRIVVMEGGEVAECGSHETLL-AAGGLYARL 703
>ABCB7_HUMAN (O75027) ATP-binding cassette sub-family B member 7, mitochondrial| precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein) Length = 752 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/128 (30%), Positives = 68/128 (53%) Frame = -2 Query: 599 LLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAV 420 L +A+ G D+ V E G S G++Q + RA+L+ +++ DEAT+S+D+ T+ Sbjct: 587 LHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEET 646 Query: 419 LQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + ++ K+ T I +AHR+ TV+D D ++ + GKV E L+ H + + Sbjct: 647 ILGAMKDVVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANP----HSIYS 702 Query: 239 EYWSYTSN 216 E W S+ Sbjct: 703 EMWHTQSS 710
>MDR2_ARATH (Q8LPK2) Multidrug resistance protein 2 (P-glycoprotein 2)| Length = 1233 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/111 (33%), Positives = 63/111 (56%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G + V E G S GQRQ + RA+L+ IL+LDEAT+++D ++ V+Q+ + Sbjct: 1116 EGYSTKVGERGVQMSGGQRQRIAIARAILKNPAILLLDEATSALDVESERVVQQALDRLM 1175 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 T + VAHR+ T+ + D + + GK+VE KL+ + + KL++ Sbjct: 1176 ANRTTVVVAHRLSTIKNADTISVLHGGKIVEQGSHRKLVLNKSGPYFKLIS 1226 Score = 68.6 bits (166), Expect = 1e-11 Identities = 38/139 (27%), Positives = 74/139 (53%), Gaps = 2/139 (1%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 + + + +G ++ V E G S GQ+Q + RA+++ IL+LDEAT+++D ++ Sbjct: 477 EAISFINNLPEGFETQVGERGIQLSGGQKQRIAISRAIVKNPSILLLDEATSALDAESEK 536 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL- 246 +Q+ + T + VAHR+ TV + D++ + +GK+VE+ L+ + L Sbjct: 537 SVQEALDRVMVGRTTVVVAHRLSTVRNADIIAVVHEGKIVEFGNHENLISNPDGAYSSLL 596 Query: 245 -VNEYWSYTSNGNI*KSLS 192 + E S N ++ ++LS Sbjct: 597 RLQETASLQRNPSLNRTLS 615
>TAP2_MOUSE (P36371) Antigen peptide transporter 2 (APT2) (Histocompatibility| antigen modifier 2) Length = 702 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/99 (36%), Positives = 63/99 (63%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E G+++ + E G ++GQ+Q + RAL+R R+L+LDEAT+++D + LQ Sbjct: 588 IGEMTNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNW 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDK 291 RS+ T++ +AHR+ TV + D VL + G++VE+D+ Sbjct: 648 -RSQGDR-TMLVIAHRLHTVQNADQVLVLKQGRLVEHDQ 684
>HLYB_ECO57 (Q46717) Alpha-hemolysin translocation ATP-binding protein hlyB| (EHEC-hlyB protein) Length = 706 Score = 70.9 bits (172), Expect = 3e-12 Identities = 37/111 (33%), Positives = 66/111 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++E ++G ++ V E G S GQRQ + RAL+ RIL+ DEAT+++D ++ ++ K Sbjct: 588 IRELKEGYNTIVGEQGVGLSGGQRQRIAIARALVTNPRILIFDEATSALDYESENIIMKN 647 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 + K TVI +AHR+ TV + + ++ M +G + E +L+ + SL+ Sbjct: 648 MSRICKNRTVIIIAHRLSTVKNANRIIVMDNGFISEDGTHKELISKKDSLY 698
>PMD1_SCHPO (P36619) Leptomycin B resistance protein pmd1| Length = 1362 Score = 70.5 bits (171), Expect = 4e-12 Identities = 34/124 (27%), Positives = 69/124 (55%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT 429 K + E + G ++ + GS+ S GQ+Q + RAL+R +IL+LDEAT+++D+ + Sbjct: 1234 KANIHEFILGLPNGYNTLCGQKGSSLSGGQKQRIAIARALIRNPKILLLDEATSALDSHS 1293 Query: 428 DAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHK 249 + V+Q+ + + + T + +AHR+ ++ D D + G + E +L++ G + Sbjct: 1294 EKVVQEALNAASQGRTTVAIAHRLSSIQDADCIFVFDGGVIAEAGTHAELVKQRGRYYEL 1353 Query: 248 LVNE 237 +V + Sbjct: 1354 VVEQ 1357 Score = 67.4 bits (163), Expect = 3e-11 Identities = 31/100 (31%), Positives = 64/100 (64%) Frame = -2 Query: 560 SHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYCT 381 ++V + G S GQ+Q + RA++ +IL+LDEAT+++D+ ++ ++QK + + + T Sbjct: 559 TNVGQRGFLMSGGQKQRIAIARAVISDPKILLLDEATSALDSKSEVLVQKALDNASRSRT 618 Query: 380 VITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 I +AHR+ T+ + D ++ ++ GK+VE +L++ G+ Sbjct: 619 TIVIAHRLSTIRNADNIVVVNAGKIVEQGSHNELLDLNGA 658
>YFIC_BACSU (P54719) Hypothetical ABC transporter ATP-binding protein yfiC| Length = 604 Score = 70.1 bits (170), Expect = 5e-12 Identities = 32/108 (29%), Positives = 65/108 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 ++ +G D+ + ++GS S GQ+QL + RA+L +L+LDEAT++ID T+ +Q+ Sbjct: 485 IERLPKGYDTVLTQNGSGISQGQKQLISIARAVLADPVLLILDEATSNIDTVTEVNIQEA 544 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + T + +AHR+ T+ D ++ + +G+++E +L+ +G Sbjct: 545 LARLMEGRTSVIIAHRLNTIQRADQIVVLKNGEMIEKGSHDELIRQKG 592
>MDR18_ARATH (Q9LSJ8) Multidrug resistance protein 18 (P-glycoprotein 16)| Length = 1228 Score = 70.1 bits (170), Expect = 5e-12 Identities = 36/108 (33%), Positives = 64/108 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + G + V E G + S GQ+Q + RAL++ IL+LDEAT+++D ++ V+Q+ Sbjct: 467 ISQFPHGYQTQVGERGVHMSGGQKQRIAIARALIKSPIILLLDEATSALDLESERVVQEA 526 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + T I +AHR+ T+ + D++ + +G +VE KLME +G Sbjct: 527 LDNASVGRTTIVIAHRLSTIRNADIICVLHNGCIVETGSHDKLMEIDG 574 Score = 68.2 bits (165), Expect = 2e-11 Identities = 32/98 (32%), Positives = 56/98 (57%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + G D++ + G S GQ+Q + R +L+ IL+LDEAT+++D+ ++ V+Q Sbjct: 1102 EFITSLSDGYDTYCGDRGVQLSGGQKQRIAIARTILKNPSILLLDEATSALDSQSERVVQ 1161 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVE 300 + T + +AHR+ T+ +CD + + GKVVE Sbjct: 1162 DALEHVMVGKTSVVIAHRLSTIQNCDTIAVLDKGKVVE 1199
>MDR65_DROME (Q00748) Multidrug resistance protein homolog 65 (EC 3.6.3.44)| (P-glycoprotein 65) Length = 1302 Score = 70.1 bits (170), Expect = 5e-12 Identities = 36/108 (33%), Positives = 68/108 (62%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 G D+ + G+ S GQ+Q + RAL+R +IL+LDEAT+++D ++ ++Q+ + + Sbjct: 1189 GYDTRMGARGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDLQSEQLVQQALDTACS 1248 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 T I +AHR+ TV + D++ + +G+VVE +L+ ++G ++ KL Sbjct: 1249 GRTCIVIAHRLSTVQNADVICVIQNGQVVEQGNHMQLI-SQGGIYAKL 1295 Score = 68.9 bits (167), Expect = 1e-11 Identities = 37/114 (32%), Positives = 64/114 (56%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + + S + E GS S GQ+Q + RAL++ +IL+LDEAT+++D ++ +Q Sbjct: 524 EFITNLPESYRSMIGERGSQLSGGQKQRIAIARALIQNPKILLLDEATSALDYQSEKQVQ 583 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFH 252 + + K T I V+HR+ + D ++ + DGKV+E LM EG+ ++ Sbjct: 584 QALDLASKGRTTIVVSHRLSAIRGADKIVFIHDGKVLEEGSHDDLMALEGAYYN 637
>MCJD_ECOLI (Q9X2W0) Microcin J25 export ATP-binding/permease protein mcjD| (Microcin J25 secretion ATP-binding protein mcjD) (Microcin J25 immunity protein) Length = 580 Score = 70.1 bits (170), Expect = 5e-12 Identities = 32/98 (32%), Positives = 59/98 (60%) Frame = -2 Query: 596 LEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVL 417 L V + LD+H++ G+N+S GQ+Q L R LR+ I+++DEAT+++D ++ + Sbjct: 460 LSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINESEI 519 Query: 416 QKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVV 303 +IR+ F +I ++HRI + D V +++G +V Sbjct: 520 LSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIV 557
>Y4GM_RHISN (P55469) Probable ABC transporter ATP-binding protein y4gM| Length = 586 Score = 70.1 bits (170), Expect = 5e-12 Identities = 34/108 (31%), Positives = 61/108 (56%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + G D+ V E+G S GQ+Q + RA+LR IL+ DEAT+++D+ ++ +++ Sbjct: 465 IMKMPHGYDTEVGENGIKLSGGQKQRITIARAMLRNAEILIFDEATSALDSESEIQIRQA 524 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + T I +AHR+ TV D ++ M G+V E +L+ +G Sbjct: 525 LARLTRKRTTIMIAHRLSTVTAADNIVVMEGGQVAEQGPQGRLLSQDG 572
>MDR13_ARATH (Q9LHD1) Multidrug resistance protein 13 (P-glycoprotein 15)| Length = 1240 Score = 70.1 bits (170), Expect = 5e-12 Identities = 35/116 (30%), Positives = 67/116 (57%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + G ++ V E G S GQ+Q + RA+++ IL+LDEAT+++D+ ++ V+Q+ Sbjct: 480 ISQLPNGYETQVGERGVQMSGGQKQRIAIARAIIKSPTILLLDEATSALDSESERVVQEA 539 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 + + T I +AHR+ T+ + D++ + +G +VE +LME + LV+ Sbjct: 540 LENASIGRTTILIAHRLSTIRNADVISVVKNGHIVETGSHDELMENIDGQYSTLVH 595 Score = 68.9 bits (167), Expect = 1e-11 Identities = 34/122 (27%), Positives = 68/122 (55%), Gaps = 9/122 (7%) Frame = -2 Query: 614 LDKCQLLEAVQEKE---------QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVL 462 +D+ +++EA + +G D++ + G S GQ+Q + RA+L+ +L+L Sbjct: 1100 IDEAEIIEAAKAANAHDFITSLTEGYDTYCGDRGVQLSGGQKQRIAIARAVLKNPSVLLL 1159 Query: 461 DEATASIDNATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTK 282 DEAT+++D+ ++ V+Q + T + +AHR+ T+ +CD + + GK+VE + Sbjct: 1160 DEATSALDSQSERVVQDALERVMVGRTSVVIAHRLSTIQNCDAIAVLDKGKLVERGTHSS 1219 Query: 281 LM 276 L+ Sbjct: 1220 LL 1221
>YFIB_BACSU (P54718) Hypothetical ABC transporter ATP-binding protein yfiB| Length = 573 Score = 69.7 bits (169), Expect = 6e-12 Identities = 37/119 (31%), Positives = 72/119 (60%) Frame = -2 Query: 602 QLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDA 423 Q+ E + + G D+ + + G N S GQ+Q + RAL+R+ IL+LD++T+++D T+A Sbjct: 445 QIHETILKLPNGYDTVLGQRGVNLSGGQKQRISIARALIRKPAILLLDDSTSALDLQTEA 504 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 L + I + +CT + + +I T M D +L + DG+++E ++L+ +E L+ ++ Sbjct: 505 KLLEAIST--YHCTTLIITQKITTAMKADQILLLEDGELIEKGTHSELL-SESQLYKRI 560
>Y019_MYCPN (P75094) Hypothetical ABC transporter ATP-binding protein MG015| homolog (D12_orf634) Length = 634 Score = 69.7 bits (169), Expect = 6e-12 Identities = 35/120 (29%), Positives = 69/120 (57%), Gaps = 3/120 (2%) Frame = -2 Query: 614 LDKCQLLEA---VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATAS 444 ++ C++ A + QG ++ + S+G+RQL + RA++R +L+LDEAT+S Sbjct: 504 IEACKVANAHDFIMRLPQGYNTFISNKTDYLSVGERQLLTIARAVIRNAPVLLLDEATSS 563 Query: 443 IDNATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ID ++ ++Q++I K T ++HR+ + + +++ ++DGKV+E +LM G Sbjct: 564 IDVHSEKLIQQSIGRLMKDKTSFIISHRLSIIRNATLIIVINDGKVLEMGNHEQLMRQNG 623
>YNT9_SCHPO (Q9Y7M7) Probable ATP-dependent permease C9B6.09c| Length = 726 Score = 69.3 bits (168), Expect = 8e-12 Identities = 38/102 (37%), Positives = 61/102 (59%), Gaps = 2/102 (1%) Frame = -2 Query: 542 GSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRS--EFKYCTVITV 369 G S GQ+Q + RALLR L+LDEAT+++D + ++ KTI+S + T IT+ Sbjct: 617 GLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNRSMTTITI 676 Query: 368 AHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 AH++ T+ D ++ + DGKV+E +L G+ F+KL+ Sbjct: 677 AHKLATIRRADQIIVVGDGKVLEQGSFERL-SRPGTNFYKLM 717
>STE6_YEAST (P12866) Mating factor A secretion protein STE6 (Multiple drug| resistance protein homolog) (P-glycoprotein) Length = 1290 Score = 69.3 bits (168), Expect = 8e-12 Identities = 35/112 (31%), Positives = 61/112 (54%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 QGLD+ + D + S GQ Q C+ RALLR+ +IL+LDE T+++D+ + +++ + ++ Sbjct: 1179 QGLDTRI--DTTLLSGGQAQRLCIARALLRKSKILILDECTSALDSVSSSIINEIVKKGP 1236 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 + + H + C+ + + DGKVVE L G LF + N+ Sbjct: 1237 PALLTMVITHSEQMMRSCNSIAVLKDGKVVERGNFDTLYNNRGELFQIVSNQ 1288 Score = 57.4 bits (137), Expect = 3e-08 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 6/132 (4%) Frame = -2 Query: 611 DKCQLL---EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASI 441 D CQ+ + + GL++ + G S GQ+Q + RA +R IL LDEA +++ Sbjct: 477 DACQMALLDRFILDLPDGLETLIGTGGVTLSGGQQQRVAIARAFIRDTPILFLDEAVSAL 536 Query: 440 DNATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLM---ET 270 D +L K IR K T I + H + + D + M +G+VVE ++L+ T Sbjct: 537 DIVHRNLLMKAIRHWRKGKTTIILTHELSQIESDDYLYLMKEGEVVESGTQSELLADPTT 596 Query: 269 EGSLFHKLVNEY 234 S ++ L N+Y Sbjct: 597 TFSTWYHLQNDY 608
>ABCB8_HUMAN (Q9NUT2) ATP-binding cassette sub-family B member 8, mitochondrial| precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1) Length = 735 Score = 69.3 bits (168), Expect = 8e-12 Identities = 37/117 (31%), Positives = 71/117 (60%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + +G ++ V E G+ S GQ+Q + RAL+++ +L+LDEAT+++D ++ V+Q Sbjct: 592 EFITSFPEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQ 651 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + + TV+ +AHR+ TV ++ M+DG+V E +L++ +G L+ +L+ Sbjct: 652 EALDRASAGRTVLVIAHRLSTVRGAHCIVVMADGRVWEAGTHEELLK-KGGLYAELI 707
>CHVA_AGRTU (P0A2V1) Beta-(1-->2)glucan export ATP-binding protein chvA| (Attachment protein) Length = 588 Score = 69.3 bits (168), Expect = 8e-12 Identities = 35/96 (36%), Positives = 58/96 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + G + V E G+ S G+RQ + RA+L+ ILVLDEAT+++D T+A ++ Sbjct: 454 IDSRINGYLTQVGERGNRLSGGERQRIAIARAILKNAPILVLDEATSALDVETEARVKAA 513 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVE 300 + + K T +AHR+ TV D D+VL + G+++E Sbjct: 514 VDALRKNRTTFIIAHRLSTVRDADLVLFLDQGRIIE 549
>CHVA_AGRT5 (P0A2V0) Beta-(1-->2)glucan export ATP-binding protein chvA| (Attachment protein) Length = 588 Score = 69.3 bits (168), Expect = 8e-12 Identities = 35/96 (36%), Positives = 58/96 (60%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + G + V E G+ S G+RQ + RA+L+ ILVLDEAT+++D T+A ++ Sbjct: 454 IDSRINGYLTQVGERGNRLSGGERQRIAIARAILKNAPILVLDEATSALDVETEARVKAA 513 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVE 300 + + K T +AHR+ TV D D+VL + G+++E Sbjct: 514 VDALRKNRTTFIIAHRLSTVRDADLVLFLDQGRIIE 549
>MDLB_BUCBP (Q89A96) Multidrug resistance-like ATP-binding protein mdlB (EC| 3.6.3.44) Length = 578 Score = 68.9 bits (167), Expect = 1e-11 Identities = 34/105 (32%), Positives = 64/105 (60%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L +L++ V +GL + + E+G+ S+GQ+QL + R L+ +IL+LDEAT+++D Sbjct: 449 LKTIKLIQFVNSLPKGLKTLLGENGNILSIGQKQLLSIARTLISCPKILILDEATSNVDL 508 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVE 300 T+ ++K + S T+I + HR+ T+ D + ++G++VE Sbjct: 509 DTENNIKKILSSVKHLTTIIAITHRLSTIKHADNIFVFNNGEIVE 553
>Y663_HAEIN (P71355) Hypothetical ABC transporter ATP-binding protein HI0663| Length = 560 Score = 68.9 bits (167), Expect = 1e-11 Identities = 35/118 (29%), Positives = 68/118 (57%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 L++ L + V++ GLD ++ G+N S GQ Q L RALL + + DEAT++ID Sbjct: 424 LEQVNLAQFVRDNG-GLDMQLLSRGANLSGGQIQRLALARALLHNAELYIFDEATSNIDV 482 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 ++ ++ + I+ + T++ ++HR+ ++ D + + GK++E +LME +G+ Sbjct: 483 ESEEIILQFIQQFKQQKTIVMISHRLANAVNADCINVLDQGKLIEQGTHKELMEKQGA 540
>TAGC_DICDI (Q23868) Prestalk-specific protein tagC precursor (EC 3.4.21.-)| Length = 1743 Score = 68.6 bits (166), Expect = 1e-11 Identities = 36/118 (30%), Positives = 68/118 (57%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E +++ Q D+ + GS S GQ++ + RA+ + +I++LDE TA +D ++ + Sbjct: 1570 EFIKDLPQQYDTVLGSAGSLLSGGQKKRIAIARAICAKRKIMLLDEITAELDPESEEAIT 1629 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVN 240 ++I+ + TV+ VAH++ V DCD + + G +VE +LME +G +H++ N Sbjct: 1630 QSIKVLTQGHTVVMVAHKVAAVRDCDKIFVLDKGYLVEEGTHDELMERKGK-YHRMFN 1686
>MDR21_ARATH (Q9LSJ2) Putative multidrug resistance protein 21 (P-glycoprotein 22)| Length = 1262 Score = 68.6 bits (166), Expect = 1e-11 Identities = 35/122 (28%), Positives = 67/122 (54%), Gaps = 9/122 (7%) Frame = -2 Query: 614 LDKCQLLEAVQEKE---------QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVL 462 +D+ +++EA + G D++ + G S GQ+Q + RA+L+ +L+L Sbjct: 1122 IDESEIIEAAKAANAHDFIVTLSDGYDTYCGDRGVQLSGGQKQRIAIARAVLKNPSVLLL 1181 Query: 461 DEATASIDNATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTK 282 DEAT+++DN ++ ++Q + T + +AHR+ T+ +CD + + GKVVE + Sbjct: 1182 DEATSALDNQSERMVQDALGRLMVGRTSVVIAHRLSTIQNCDTITVLDKGKVVECGTHSS 1241 Query: 281 LM 276 L+ Sbjct: 1242 LL 1243 Score = 67.0 bits (162), Expect = 4e-11 Identities = 34/109 (31%), Positives = 63/109 (57%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 G + V E G S GQ+Q + RA+++ +L+LDEAT+++D+ ++ V+Q+ + + Sbjct: 506 GYKTQVGERGVQMSGGQKQRISIARAIIKSPTLLLLDEATSALDSESERVVQEALDNATI 565 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 T I +AHR+ T+ + D++ +G++VE +LME + LV Sbjct: 566 GRTTIVIAHRLSTIRNVDVICVFKNGQIVETGSHEELMENVDGQYTSLV 614
>MDR11_ARATH (Q9LJX0) Multidrug resistance protein 11 (P-glycoprotein 19)| Length = 1252 Score = 68.2 bits (165), Expect = 2e-11 Identities = 34/110 (30%), Positives = 63/110 (57%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G + V E G S GQ+Q + RA+L+ +L+LDEAT+++D ++ VLQ+ + Sbjct: 1136 EGYKTPVGERGVQLSGGQKQRIAIARAVLKNPTVLLLDEATSALDAESECVLQEALERLM 1195 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + T + VAHR+ T+ D + + DG++VE ++L+ + +L+ Sbjct: 1196 RGRTTVVVAHRLSTIRGVDCIGVIQDGRIVEQGSHSELVSRPEGAYSRLL 1245 Score = 67.8 bits (164), Expect = 2e-11 Identities = 34/104 (32%), Positives = 63/104 (60%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G D+ V E G S GQ+Q + RA+L+ +IL+LDEAT+++D ++++++Q+ + Sbjct: 491 KGYDTQVGERGVQLSGGQKQRIAIARAMLKDPKILLLDEATSALDASSESIVQEALDRVM 550 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGS 261 T + VAHR+ T+ + D + + G+VVE +L+ G+ Sbjct: 551 VGRTTVVVAHRLCTIRNVDSIAVIQQGQVVETGTHEELIAKSGA 594
>YD01_SCHPO (O14286) Putative ABC transporter C15A10.01 in chromosome I| Length = 693 Score = 68.2 bits (165), Expect = 2e-11 Identities = 39/138 (28%), Positives = 71/138 (51%), Gaps = 5/138 (3%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNAT 429 K ++ + ++ +G + V E G S G++Q + R LL+ IL DEAT+++D T Sbjct: 555 KAKIHDIIESFPEGYQTKVGERGLMISGGEKQRLAVSRLLLKNPEILFFDEATSALDTNT 614 Query: 428 DAVLQKTIRSEFK--YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG--- 264 + L + I K + T + +AHR+ T+ DCD++ + G+VVE +LM Sbjct: 615 ERALLRNINDLIKGSHKTSVFIAHRLRTIKDCDIIFVLEKGRVVEQGSHEQLMAKNSVYT 674 Query: 263 SLFHKLVNEYWSYTSNGN 210 S++H + + +G+ Sbjct: 675 SMWHSQESPFGESNKSGD 692
>MDR3_CAEEL (P34713) Multidrug resistance protein 3 (EC 3.6.3.44) (P-glycoprotein| C) Length = 1268 Score = 67.8 bits (164), Expect = 2e-11 Identities = 34/111 (30%), Positives = 64/111 (57%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 G D+ V G S GQ+Q + RA++R +IL+LDEAT+++D ++ ++Q+ + Sbjct: 1156 GYDTSVGASGGRLSGGQKQRVAIARAIVRDPKILLLDEATSALDTESEKIVQEALDKARL 1215 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNE 237 T + +AHR+ T+ + D ++ +GK +E L+ G L+++LV + Sbjct: 1216 GRTCVVIAHRLSTIQNADKIIVCRNGKAIEEGTHQTLLARRG-LYYRLVEK 1265 Score = 57.8 bits (138), Expect = 3e-08 Identities = 26/96 (27%), Positives = 55/96 (57%) Frame = -2 Query: 530 SMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYCTVITVAHRIPT 351 S GQ+Q + RA++R+ +IL+LDEAT+++D ++ ++Q + + T + +AHR+ T Sbjct: 516 SGGQKQRVAIARAIVRKPQILLLDEATSALDTESERMVQTALDKASEGRTTLCIAHRLST 575 Query: 350 VMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + + +L G + E +L+ + ++ +V Sbjct: 576 IRNASKILVFDQGLIAERGTHDELISKDDGIYASMV 611
>MDR1_ARATH (Q9ZR72) Multidrug resistance protein 1 (P-glycoprotein 1) (AtPgp1)| Length = 1286 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/100 (33%), Positives = 59/100 (59%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEF 393 +G ++V E G S GQ+Q + RAL+R+ I++LDEAT+++D ++ +Q+ + Sbjct: 1150 EGYKTYVGERGVQLSGGQKQRIAIARALVRKAEIMLLDEATSALDAESERSVQEALDQAC 1209 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLME 273 T I VAHR+ T+ + ++ + DGKV E + L++ Sbjct: 1210 SGRTSIVVAHRLSTIRNAHVIAVIDDGKVAEQGSHSHLLK 1249 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/110 (31%), Positives = 62/110 (56%), Gaps = 1/110 (0%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 G D+ V E G S GQ+Q + RA+L+ IL+LDEAT+++D+ ++ ++Q+ + Sbjct: 495 GFDTQVGERGLQLSGGQKQRIAIARAMLKNPAILLLDEATSALDSESEKLVQEALDRFMI 554 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLM-ETEGSLFHKLV 243 T + +AHR+ T+ D+V + G V E +L + E ++ KL+ Sbjct: 555 GRTTLIIAHRLSTIRKADLVAVLQQGSVSEIGTHDELFSKGENGVYAKLI 604
>Y014_MYCGE (P47260) Hypothetical ABC transporter ATP-binding protein MG014| Length = 623 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/114 (28%), Positives = 66/114 (57%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 +++ D +V + G N S GQ+Q + R L+ + RILV D++ +++D T+ +++ Sbjct: 496 IEKFSDSYDHNVEQLGKNLSGGQKQRVAIARTLITKPRILVFDDSMSALDALTEKKVREN 555 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKL 246 I ++ K T I ++ I ++ D +L + +G++V +D KLM+ SL+ K+ Sbjct: 556 IENDLKLTTKIIISQNINSIKHADKILVIDNGRIVGFDSDQKLMK-NCSLYQKM 608
>CYDD_HAEIN (P45082) Transport ATP-binding protein cydD| Length = 586 Score = 66.2 bits (160), Expect = 7e-11 Identities = 32/97 (32%), Positives = 56/97 (57%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 GL + + G S+GQ Q + RALLR+ +L+LDE TAS+D ++ ++ + + + Sbjct: 472 GLHHEIKDGGLGISVGQAQRLAIARALLRKGDLLLLDEPTASLDAQSENLVLQALNEASQ 531 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKL 279 + T + + HRI + CD + M G++V+ K T+L Sbjct: 532 HQTTLMITHRIEDLKQCDQIFVMQRGEIVQQGKFTEL 568
>ABCB6_HUMAN (Q9NP58) ATP-binding cassette sub-family B member 6, mitochondrial| precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat) Length = 842 Score = 66.2 bits (160), Expect = 7e-11 Identities = 34/110 (30%), Positives = 61/110 (55%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 +A+ +G + V E G S G++Q + R +L+ I++LDEAT+++D + + +Q Sbjct: 707 DAIMAFPEGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQ 766 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ++ T I VAHR+ TV++ D +L + DG +VE + L+ G Sbjct: 767 ASLAKVCANRTTIVVAHRLSTVVNADQILVIKDGCIVERGRHEALLSRGG 816
>MDL1_CANAL (P97998) ATP-dependent permease MDL1| Length = 685 Score = 65.9 bits (159), Expect = 9e-11 Identities = 37/122 (30%), Positives = 73/122 (59%), Gaps = 4/122 (3%) Frame = -2 Query: 587 VQEKEQGLDSHV-VEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQK 411 V+ GLD+ + + + S GQ+Q L R L+R +IL+LDEAT+++D+ ++ ++ Sbjct: 561 VRHLPDGLDTKIGASNSTQLSGGQKQRVSLARTLIRDPKILILDEATSALDSVSEEIVMS 620 Query: 410 TI--RSEFKYCTVITVAHRIPTVMDCDMVLAMS-DGKVVEYDKPTKLMETEGSLFHKLVN 240 + ++ + T+I++AHR+ T+ + D ++ + DG++VE K +L S F+KL+ Sbjct: 621 NLIQLNKNRGVTLISIAHRLSTIKNSDRIIVFNQDGQIVEDGKFNELHNDPNSQFNKLLK 680 Query: 239 EY 234 + Sbjct: 681 SH 682
>MDR20_ARATH (Q9LSJ5) Putative multidrug resistance protein 20 (P-glycoprotein 18)| Length = 1225 Score = 65.9 bits (159), Expect = 9e-11 Identities = 34/122 (27%), Positives = 66/122 (54%), Gaps = 9/122 (7%) Frame = -2 Query: 614 LDKCQLLEA---------VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVL 462 +D+ +++EA + G D+ + G S GQ+Q + RA+L+ +L+L Sbjct: 1085 IDESEIIEAAKAANAHDFITSLSNGYDTCCGDRGVQLSGGQKQRIAIARAVLKNPSVLLL 1144 Query: 461 DEATASIDNATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTK 282 DEAT+++D+ +++V+Q + T + +AHR+ T+ CD + + +G VVE + Sbjct: 1145 DEATSALDSQSESVVQDALERLMVGRTSVVIAHRLSTIQKCDTIAVLENGAVVECGNHSS 1204 Query: 281 LM 276 L+ Sbjct: 1205 LL 1206 Score = 63.9 bits (154), Expect = 4e-10 Identities = 32/106 (30%), Positives = 63/106 (59%) Frame = -2 Query: 560 SHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFKYCT 381 + V E G S GQ+Q + RA+++ IL+LDEAT+++D+ ++ V+Q+ + + T Sbjct: 477 TQVGERGVQLSGGQKQRIAIARAIIKSPIILLLDEATSALDSESERVVQEALDNASIGRT 536 Query: 380 VITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 I +AHR+ T+ + D++ + +G+++E +L+E + LV Sbjct: 537 TIVIAHRLSTIRNADVICVVHNGRIIETGSHEELLEKLDGQYTSLV 582
>Y1384_MYCBO (P63394) Hypothetical ABC transporter ATP-binding protein Mb1384| Length = 579 Score = 65.9 bits (159), Expect = 9e-11 Identities = 39/121 (32%), Positives = 69/121 (57%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + G ++ V E GS S G+RQ + RALL+ +L++DEAT+++D +A + Sbjct: 450 ELIARLPDGANTIVGEAGSALSGGERQRVSIARALLKAAPVLLVDEATSALDAENEAAVV 509 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 + ++ + T + VAHR+ ++ D VL + DG+VVE ++L+ T G F +++ Sbjct: 510 DALAADPRSRTRVIVAHRLASIRHADRVLFVDDGRVVEDGSISELL-TAGGRF----SQF 564 Query: 233 W 231 W Sbjct: 565 W 565
>Y1349_MYCTU (P63393) Hypothetical ABC transporter ATP-binding protein| Rv1349/MT1392 Length = 579 Score = 65.9 bits (159), Expect = 9e-11 Identities = 39/121 (32%), Positives = 69/121 (57%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + G ++ V E GS S G+RQ + RALL+ +L++DEAT+++D +A + Sbjct: 450 ELIARLPDGANTIVGEAGSALSGGERQRVSIARALLKAAPVLLVDEATSALDAENEAAVV 509 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLVNEY 234 + ++ + T + VAHR+ ++ D VL + DG+VVE ++L+ T G F +++ Sbjct: 510 DALAADPRSRTRVIVAHRLASIRHADRVLFVDDGRVVEDGSISELL-TAGGRF----SQF 564 Query: 233 W 231 W Sbjct: 565 W 565
>TAP2_HUMAN (Q03519) Antigen peptide transporter 2 (APT2) (Peptide transporter| TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2) Length = 686 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/94 (37%), Positives = 56/94 (59%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 +QE E G+ + V E GS + GQ+Q + RAL+R R+L+LDEAT+++D + LQ Sbjct: 589 IQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDW 648 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKV 306 + TV+ +AHR+ TV +L + +GK+ Sbjct: 649 NSRGDR--TVLVIAHRLQTVQRAHQILVLQEGKL 680
>Y1304_MYCBO (P0A4W5) Hypothetical ABC transporter ATP-binding protein Mb1304c| Length = 582 Score = 64.7 bits (156), Expect = 2e-10 Identities = 33/89 (37%), Positives = 51/89 (57%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 GL + V + G N+S GQRQ + RA++RR I V D+A +++D TDA + ++R Sbjct: 462 GLQTRVAQGGVNFSGGQRQRLAIARAVIRRPAIYVFDDAFSALDVHTDAKVHASLRQVSG 521 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVV 303 T+I V RI D V+ + +GK+V Sbjct: 522 DATIIVVTQRISNAAQADQVIVVDNGKIV 550
>Y1273_MYCTU (P0A4W4) Hypothetical ABC transporter ATP-binding protein| Rv1273c/MT1311 Length = 582 Score = 64.7 bits (156), Expect = 2e-10 Identities = 33/89 (37%), Positives = 51/89 (57%) Frame = -2 Query: 569 GLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRSEFK 390 GL + V + G N+S GQRQ + RA++RR I V D+A +++D TDA + ++R Sbjct: 462 GLQTRVAQGGVNFSGGQRQRLAIARAVIRRPAIYVFDDAFSALDVHTDAKVHASLRQVSG 521 Query: 389 YCTVITVAHRIPTVMDCDMVLAMSDGKVV 303 T+I V RI D V+ + +GK+V Sbjct: 522 DATIIVVTQRISNAAQADQVIVVDNGKIV 550
>CYDD_ECOLI (P29018) Transport ATP-binding protein cydD| Length = 588 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/117 (29%), Positives = 62/117 (52%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 LD + E + QG+D+ V + + S+GQ Q + RALL C +L+LDE AS+D Sbjct: 459 LDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDA 518 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 ++ + + + + T + V H++ + D D++ M DG+++E + +L G Sbjct: 519 HSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGRYAELSVAGG 575
>LCNCL_LACLA (Q9CJB8) Lactococcin transport/processing ATP-binding protein| lcnC-like (EC 3.4.22.-) Length = 715 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/115 (31%), Positives = 64/115 (55%), Gaps = 3/115 (2%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 +++ + G + + D S+ S GQ+Q L RALL +IL+LDEAT+++D T+ + K Sbjct: 602 IEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKILILDEATSNLDMITEKKILKN 661 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG---SLFH 252 + + K T+I +AHR+ ++ + GKV+E ++L+ G L+H Sbjct: 662 LLALDK--TIIFIAHRLSVAEMSHRIIVIEQGKVIESGSHSELLAQNGFYAQLYH 714
>CYDC_BACSU (P94366) Transport ATP-binding protein cydC| Length = 567 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/119 (33%), Positives = 61/119 (51%) Frame = -2 Query: 599 LLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAV 420 L E V GL+ + E G S GQ Q L RA L IL+LDE TA +D T+ Sbjct: 442 LTELVNNLPDGLEGRIGEGGRALSGGQAQRVALARAFLGNRPILLLDEPTAHLDIETEYE 501 Query: 419 LQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 +++T+ F+ V HR+ ++D D ++ + G+V E +L+E G ++ KLV Sbjct: 502 IKETMLDLFEDKLVFLATHRLHWMLDMDEIIVLDGGRVAEIGTHNELLEKNG-VYTKLV 559
>MDR22_ARATH (Q9LHK4) Putative multidrug resistance protein 22 (P-glycoprotein| 8) Length = 1241 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/115 (30%), Positives = 64/115 (55%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + + G D+H+ G+ S GQ+Q + RA++R IL+LDEAT+++D ++ ++Q Sbjct: 481 ITQLPNGYDTHIGNRGALLSGGQKQRIAIARAIIRNPVILLLDEATSALDGESETLIQNA 540 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 + T + VAH++ TV +++ + +G V E LM T+ + + KLV Sbjct: 541 LDQVAAGRTTLVVAHKLSTVRGANIIAMLENGSVRELGSHEDLM-TKNNHYAKLV 594 Score = 56.2 bits (134), Expect = 7e-08 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 + E+G + E G S GQ+Q + RA LR IL+LDE T+S+D+ ++ +Q Sbjct: 1119 ISAMEKGYKTECGERGVQLSGGQKQRIAIARAFLRSPIILLLDEVTSSLDSNSEQEVQDA 1178 Query: 407 IR--SEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVE 300 + + T + VAHR+ T+ + D + + DG V+E Sbjct: 1179 LARIMASRNMTTVVVAHRLNTLKNLDCIALIVDGTVIE 1216
>COMA_STRR6 (P59653) Transport/processing ATP-binding protein comA (EC| 3.4.22.-) Length = 717 Score = 63.9 bits (154), Expect = 4e-10 Identities = 39/125 (31%), Positives = 66/125 (52%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ ++ E ++ + + DG+ S GQRQ L RALL +L+LDEAT+S+D Sbjct: 595 VELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDAPVLILDEATSSLDI 654 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+ + + + K T+I +AHR+ + V+ + GK+VE K L+ +G + Sbjct: 655 LTEKRIVDNLIALDK--TLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLL-AQGGFY 711 Query: 254 HKLVN 240 LVN Sbjct: 712 AHLVN 716
>COMA_STRPN (Q03727) Transport/processing ATP-binding protein comA (EC| 3.4.22.-) Length = 717 Score = 63.9 bits (154), Expect = 4e-10 Identities = 39/125 (31%), Positives = 66/125 (52%) Frame = -2 Query: 614 LDKCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDN 435 ++ ++ E ++ + + DG+ S GQRQ L RALL +L+LDEAT+S+D Sbjct: 595 VELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDAPVLILDEATSSLDI 654 Query: 434 ATDAVLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 T+ + + + K T+I +AHR+ + V+ + GK+VE K L+ +G + Sbjct: 655 LTEKRIVDNLIALDK--TLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLL-AQGGFY 711 Query: 254 HKLVN 240 LVN Sbjct: 712 AHLVN 716
>TAGB_DICDI (P54683) Prestalk-specific protein tagB precursor (EC 3.4.21.-)| Length = 1905 Score = 63.2 bits (152), Expect = 6e-10 Identities = 33/113 (29%), Positives = 63/113 (55%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E + + + D+ + E G N S GQ++ + RA+ + +I++LDE TA +D ++ + Sbjct: 1640 EFINDLPKKYDTQIGEAG-NLSGGQKKRIAVARAICAKRKIMLLDEITAELDPESEEAIT 1698 Query: 413 KTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLF 255 ++I+ + TV+ VAH++ V DCD + + G +VE +LM +G + Sbjct: 1699 QSIKVLTQGHTVVMVAHKVAAVRDCDKIFVLEKGYLVEEGTHDELMANKGKYY 1751
>LCNC_LACLA (Q00564) Lactococcin-A transport/processing ATP-binding protein| lcnC (EC 3.4.22.-) Length = 715 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/115 (31%), Positives = 61/115 (53%), Gaps = 3/115 (2%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKT 408 +++ + G + + D S+ S GQ+Q L RALL +IL+LDEAT+++D T+ + K Sbjct: 602 IEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKILILDEATSNLDMITEKKILKN 661 Query: 407 IRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG---SLFH 252 + K T+I +AHR+ ++ + GKV+E L+ G L+H Sbjct: 662 LLPLDK--TIIFIAHRLSVAEMSHRIIVVDQGKVIESGSHVDLLAQNGFYEQLYH 714
>LAGD_LACLA (P59852) Lactococcin-G-processing and transport ATP-binding protein| lagD (EC 3.4.22.-) Length = 703 Score = 62.0 bits (149), Expect = 1e-09 Identities = 36/121 (29%), Positives = 67/121 (55%), Gaps = 1/121 (0%) Frame = -2 Query: 599 LLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD-A 423 L++ + ++ DS + E G+N S GQ+Q + RA+L I++ DEAT+ +D + Sbjct: 585 LVDFINQQPLRFDSVLEEGGNNLSGGQKQRLAIARAILNDSEIIIFDEATSGLDTLLEKE 644 Query: 422 VLQKTIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEGSLFHKLV 243 +L+ I+ + K T+I +AH + CD ++ + G +V +L E EG ++ +L+ Sbjct: 645 ILEYLIKLQDK--TIIFIAHHLSIAKACDEIIVLDQGILVGRGTHEELSEKEG-VYRRLL 701 Query: 242 N 240 N Sbjct: 702 N 702
>MDL2_YEAST (P33311) ATP-dependent permease MDL2, mitochondrial precursor| (Multidrug resistance-like protein 2) Length = 773 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/112 (32%), Positives = 64/112 (57%), Gaps = 3/112 (2%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTIRS--EFK 390 D+ + G+ S GQ+Q + RAL+++ IL+LDEAT+++D ++ + T + K Sbjct: 576 DTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSK 635 Query: 389 YCTVITVAHRIPTVMDCDMVLAMS-DGKVVEYDKPTKLMETEGSLFHKLVNE 237 T++++AHR+ T+ + V+ + DG VVE K +L S +L+NE Sbjct: 636 SMTIVSIAHRLSTIRRSENVIVLGHDGSVVEMGKFKELYANPTSALSQLLNE 687
>TAP1_GORGO (Q28433) Antigen peptide transporter 1 (APT1) (Peptide transporter| TAP1) (ATP-binding cassette sub-family B member 2) Length = 748 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Frame = -2 Query: 608 KCQLLEAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASID-NA 432 KC + QG D+ V E GS S GQRQ L RAL+R+ +L+LD+AT+++D N+ Sbjct: 618 KCGAHSFISGLPQGYDTEVGEAGSQLSGGQRQAVALARALIRKPCVLILDDATSALDANS 677 Query: 431 TDAVLQKTIRSEFKYC-TVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 V Q S +Y +V+ + + V D +L + G + E +LME +G Sbjct: 678 QLQVEQLLYESPERYSRSVLLITQHLSLVEQADHILFLEGGAIREGGTHQQLMEKKG 734
>TAP1_RAT (P36370) Antigen peptide transporter 1 (APT1) (Peptide transporter| TAP1) (ATP-binding cassette sub-family B member 2) Length = 725 Score = 60.5 bits (145), Expect = 4e-09 Identities = 35/105 (33%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = -2 Query: 572 QGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTI--RS 399 QG D+ V E G+ S GQRQ L RAL+R+ R+L+LD+AT+++D +Q+ + Sbjct: 607 QGYDTEVGETGNQLSGGQRQAVALARALIRKPRLLILDDATSALDAGNQLRVQRLLYESP 666 Query: 398 EFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 E+ TV+ + ++ +L + +G V E +LME G Sbjct: 667 EWASRTVLLITQQLSLAERAHHILFLKEGSVCEQGTHLQLMERGG 711
>MDR_PLAFF (P13568) Multidrug resistance protein (EC 3.6.3.44) (Chloroquine| resistance protein) Length = 1419 Score = 60.5 bits (145), Expect = 4e-09 Identities = 33/95 (34%), Positives = 59/95 (62%), Gaps = 2/95 (2%) Frame = -2 Query: 593 EAVQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQ 414 E ++ D++V G + S GQ+Q + RALLR +IL+LDEAT+S+D+ ++ +++ Sbjct: 1292 EFIESLPNKYDTNVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIE 1351 Query: 413 KTI--RSEFKYCTVITVAHRIPTVMDCDMVLAMSD 315 KTI + T+IT+AHRI ++ D ++ ++ Sbjct: 1352 KTIVDIKDKADKTIITIAHRIASIKRSDKIVVFNN 1386 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/86 (36%), Positives = 54/86 (62%), Gaps = 3/86 (3%) Frame = -2 Query: 563 DSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATDAVLQKTI---RSEF 393 D+ V + S S GQ+Q + RA++R +IL+LDEAT+S+DN ++ ++QKTI + Sbjct: 553 DTLVGSNASKLSGGQKQRISIARAIMRNPKILILDEATSSLDNKSEYLVQKTINNLKGNE 612 Query: 392 KYCTVITVAHRIPTVMDCDMVLAMSD 315 T+I +AHR+ T+ + + +S+ Sbjct: 613 NRITII-IAHRLSTIRYANTIFVLSN 637
>PEDD_PEDAC (P36497) Pediocin PA-1 transport/processing ATP-binding protein| pedD (EC 3.4.22.-) (Pediocin AcH transport ATP-binding protein papD) Length = 724 Score = 59.7 bits (143), Expect = 7e-09 Identities = 34/109 (31%), Positives = 58/109 (53%), Gaps = 1/109 (0%) Frame = -2 Query: 587 VQEKEQGLDSHVVEDGSNWSMGQRQLFCLGRALLRRCRILVLDEATASIDNATD-AVLQK 411 ++ QG + + E G N S GQ+Q + RALL + + DE+T+++D T+ ++ K Sbjct: 608 IENLPQGYHTRLSESGFNLSGGQKQRLSIARALLSPAQCFIFDESTSNLDTITEHKIVSK 667 Query: 410 TIRSEFKYCTVITVAHRIPTVMDCDMVLAMSDGKVVEYDKPTKLMETEG 264 + + K T+I VAHR+ D V+ + GK+VE +L+ G Sbjct: 668 LLFMKDK--TIIFVAHRLNIASQTDKVVVLDHGKIVEQGSHRQLLNYNG 714 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,055,694 Number of Sequences: 219361 Number of extensions: 1847014 Number of successful extensions: 6731 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6247 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6623 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5538924943 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
