ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal29a05 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 84.3 bits (207), Expect = 3e-16 Identities = 35/77 (45%), Positives = 54/77 (70%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+SFGI+LWEL T +P++ +TP+QAA V +K RP +P + L L+++CW ++P+ Sbjct: 269 VYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPS 328 Query: 476 ERPDFSEILEALKKIAE 426 +RPDFS I+ L+K E Sbjct: 329 KRPDFSNIVAVLEKYDE 345
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 75.9 bits (185), Expect = 1e-13 Identities = 36/76 (47%), Positives = 47/76 (61%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+S+G+LLWEL+TG+ PY+ PL A GV L IPK L++ CWQ DP Sbjct: 328 VWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPH 387 Query: 476 ERPDFSEILEALKKIA 429 +RP F EIL+ L+ IA Sbjct: 388 KRPGFKEILKQLESIA 403
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 75.1 bits (183), Expect = 2e-13 Identities = 35/79 (44%), Positives = 47/79 (59%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+SFG+LLWELLTG++PY + L A GV L IP +L+ CW QDP Sbjct: 305 VWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPH 364 Query: 476 ERPDFSEILEALKKIAEEV 420 RPDF+ IL+ L+ + +V Sbjct: 365 RRPDFASILQQLEALEAQV 383
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 74.7 bits (182), Expect = 2e-13 Identities = 35/77 (45%), Positives = 45/77 (58%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+SFG+LLWELLTG++PY + L A GV L IP LL++CW DP Sbjct: 286 VWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPH 345 Query: 476 ERPDFSEILEALKKIAE 426 RPDF IL+ L+ I + Sbjct: 346 GRPDFGSILKRLEVIEQ 362
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 72.8 bits (177), Expect = 9e-13 Identities = 36/82 (43%), Positives = 48/82 (58%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++S+G+LLWELLTG++PY + L A GV L IP +L+++CWQQDP Sbjct: 327 IWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPH 386 Query: 476 ERPDFSEILEALKKIAEEVGDE 411 RP F+ ILE L I V E Sbjct: 387 IRPSFALILEQLTAIEGAVMTE 408
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 70.9 bits (172), Expect = 3e-12 Identities = 32/76 (42%), Positives = 49/76 (64%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+ F +++WE+LTG+IP+ L Q + V GLRP IP+ +L LL +CW+ DP Sbjct: 293 VYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPN 352 Query: 476 ERPDFSEILEALKKIA 429 +RP F+ I+ LK+I+ Sbjct: 353 DRPPFTYIVNKLKEIS 368
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 70.1 bits (170), Expect = 6e-12 Identities = 32/77 (41%), Positives = 44/77 (57%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+S+G+LLWELLTG++P+ + L A GV L IP +L++ CW DP Sbjct: 332 VWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPH 391 Query: 476 ERPDFSEILEALKKIAE 426 RP F+ IL+ L I E Sbjct: 392 SRPSFTNILDQLTTIEE 408
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 70.1 bits (170), Expect = 6e-12 Identities = 30/77 (38%), Positives = 50/77 (64%) Frame = -3 Query: 653 FSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAE 474 +S+G++LWE+LT ++P++ L LQ A VV+K R TIP + ELL +CW+ D + Sbjct: 190 YSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKK 249 Query: 473 RPDFSEILEALKKIAEE 423 RP F +I+ L+ ++ + Sbjct: 250 RPSFKQIISILESMSND 266
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 70.1 bits (170), Expect = 6e-12 Identities = 30/77 (38%), Positives = 50/77 (64%) Frame = -3 Query: 653 FSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPAE 474 +S+G++LWE+LT ++P++ L LQ A VV+K R TIP + ELL +CW+ D + Sbjct: 190 YSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKK 249 Query: 473 RPDFSEILEALKKIAEE 423 RP F +I+ L+ ++ + Sbjct: 250 RPSFKQIISILESMSND 266
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 68.6 bits (166), Expect = 2e-11 Identities = 34/79 (43%), Positives = 48/79 (60%), Gaps = 4/79 (5%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNA----HAKLTELLQKCWQ 489 V+SFGI+LWELLT + PY+ +TP AV V++ G+RP I A + +L+++CW Sbjct: 970 VYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWH 1029 Query: 488 QDPAERPDFSEILEALKKI 432 D RP F EI+ L I Sbjct: 1030 SDTIIRPTFLEIMTRLSNI 1048 Score = 63.5 bits (153), Expect = 5e-10 Identities = 27/78 (34%), Positives = 50/78 (64%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 VFSFG+++WE+LTGK P+ ++ ++ +++ G RP IP + + +L++KCW Sbjct: 1543 VFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGG-RPIIPSDCPHEFAKLIKKCWHAKAH 1601 Query: 476 ERPDFSEILEALKKIAEE 423 +RP +E+++ L I E+ Sbjct: 1602 KRPTMTEVVQQLMLITEQ 1619
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 67.0 bits (162), Expect = 5e-11 Identities = 29/78 (37%), Positives = 52/78 (66%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SF +LLWEL+T ++P+ L+ ++ + V +GLRPTIP + +L++ C +DPA Sbjct: 375 MWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPA 434 Query: 476 ERPDFSEILEALKKIAEE 423 +RP F I+ L+K+ ++ Sbjct: 435 KRPKFDMIVPILEKMQDK 452
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 66.6 bits (161), Expect = 6e-11 Identities = 28/78 (35%), Positives = 52/78 (66%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SF +LLWEL+T ++P+ L+ ++ + V +GLRPT+P + +L++ C +DPA Sbjct: 375 MWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTVPPGISPHVCKLMKICMNEDPA 434 Query: 476 ERPDFSEILEALKKIAEE 423 +RP F I+ L+K+ ++ Sbjct: 435 KRPKFDMIVPILEKMQDK 452
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 64.7 bits (156), Expect = 2e-10 Identities = 32/84 (38%), Positives = 54/84 (64%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ T G PY + P++ ++++G R P N ++L L+++CW P Sbjct: 670 VWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAP 728 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 ++RP F +++EAL K+ V +E+ Sbjct: 729 SQRPTFKQLVEALDKVLLAVSEEY 752
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 63.9 bits (154), Expect = 4e-10 Identities = 28/78 (35%), Positives = 51/78 (65%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SF +LLWEL+T ++P+ L+ ++ + V +GLRPTIP + +L++ C +DPA Sbjct: 375 MWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPA 434 Query: 476 ERPDFSEILEALKKIAEE 423 +R F I+ L+K+ ++ Sbjct: 435 KRSKFDMIVPILEKMQDK 452
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/79 (41%), Positives = 49/79 (62%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ + G++PY + PL+ V V+KG + P A + E+++KCW DP Sbjct: 369 VWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCWTLDP 427 Query: 479 AERPDFSEILEALKKIAEE 423 RP F ++ E L I E+ Sbjct: 428 GHRPSFHQLREQLVHIKEK 446
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 62.8 bits (151), Expect = 9e-10 Identities = 32/78 (41%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T GK+P+E + LQ V + +G R P A + E++ CW + P Sbjct: 449 VWSFGVLMWEVFTEGKMPFENKSNLQV-VEAISEGFRLYRPHLAPMSIYEVMYSCWHEKP 507 Query: 479 AERPDFSEILEALKKIAE 426 RP F+E+L A+ +IAE Sbjct: 508 EGRPTFAELLRAVTEIAE 525
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 62.4 bits (150), Expect = 1e-09 Identities = 27/75 (36%), Positives = 46/75 (61%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+SFG++LWEL T + P+ L P Q V K R IP+N + ++ +++ CW +P Sbjct: 734 VYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPW 793 Query: 476 ERPDFSEILEALKKI 432 +RP F+ I++ L+ + Sbjct: 794 KRPSFATIMDLLRPL 808
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 62.4 bits (150), Expect = 1e-09 Identities = 29/74 (39%), Positives = 45/74 (60%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 VFS+ + LWELLTG+IP+ +L P AA + +RP I + ++ LL + W P Sbjct: 647 VFSYSLCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPE 706 Query: 476 ERPDFSEILEALKK 435 RP+FSE++ L++ Sbjct: 707 GRPEFSEVVSKLEE 720
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 62.0 bits (149), Expect = 2e-09 Identities = 31/84 (36%), Positives = 53/84 (63%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ T G PY + P++ ++++G R P + +L L+++CW P Sbjct: 672 VWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAP 730 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 ++RP F +++EAL K+ V +E+ Sbjct: 731 SQRPTFKQLVEALDKVLLAVSEEY 754
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 61.6 bits (148), Expect = 2e-09 Identities = 31/84 (36%), Positives = 53/84 (63%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SF ILLWE+ T G PY + P++ ++++G R P N ++L L+++CW P Sbjct: 669 VWSFEILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAP 727 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 ++RP F +++EAL K+ V +E+ Sbjct: 728 SQRPTFKQLVEALDKVLLAVSEEY 751
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 61.2 bits (147), Expect = 3e-09 Identities = 31/78 (39%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T GK+P+E + LQ V + +G R P A + ++ CW + P Sbjct: 449 VWSFGVLMWEVFTEGKMPFENKSNLQV-VEAISQGFRLYRPHLAPMTIYRVMYSCWHESP 507 Query: 479 AERPDFSEILEALKKIAE 426 RP F+E+L+ L +IAE Sbjct: 508 KGRPTFAELLQVLTEIAE 525
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 61.2 bits (147), Expect = 3e-09 Identities = 28/74 (37%), Positives = 44/74 (59%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 VFS+ + LWELL G+IP+ +L P AA + +RP I + ++ LL + W P Sbjct: 646 VFSYALCLWELLIGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRGWNACPE 705 Query: 476 ERPDFSEILEALKK 435 RP+FSE++ L++ Sbjct: 706 GRPEFSEVVRKLEE 719
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 60.8 bits (146), Expect = 3e-09 Identities = 27/78 (34%), Positives = 47/78 (60%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+S+G++L+ELLT P + + P++ A + RP IP +K E+L +CW +P Sbjct: 1488 VYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPD 1547 Query: 476 ERPDFSEILEALKKIAEE 423 RP F +I+ LK++ ++ Sbjct: 1548 SRPTFKQIIVHLKEMEDQ 1565
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 60.8 bits (146), Expect = 3e-09 Identities = 28/73 (38%), Positives = 45/73 (61%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T G++PY L + G+ + P+ ++LT+L+Q+CW P Sbjct: 970 VWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRLTKLMQRCWAPSP 1029 Query: 479 AERPDFSEILEAL 441 +RP FSE+ AL Sbjct: 1030 KDRPSFSELAAAL 1042
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 60.8 bits (146), Expect = 3e-09 Identities = 28/78 (35%), Positives = 51/78 (65%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SF +LLWEL+T ++P+ L+ ++ + V +G RPTIP + +L++ C +DPA Sbjct: 375 MWSFAVLLWELVTREVPFADLSNMEIGMKVALEG-RPTIPPGISPHVCKLMKICMNEDPA 433 Query: 476 ERPDFSEILEALKKIAEE 423 +RP F I+ L+K+ ++ Sbjct: 434 KRPKFDMIVPILEKMQDK 451
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 60.8 bits (146), Expect = 3e-09 Identities = 28/74 (37%), Positives = 45/74 (60%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 VFS+ + LWE+LTG+IP+ +L P AA + +RP I + ++ LL + W P Sbjct: 749 VFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPE 808 Query: 476 ERPDFSEILEALKK 435 RP+FSE++ L++ Sbjct: 809 GRPEFSEVVMKLEE 822
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 60.1 bits (144), Expect = 6e-09 Identities = 27/73 (36%), Positives = 44/73 (60%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 V+SFG++ +E+LTG +P+ +V +G+RP +P + +L L+ CW QDP Sbjct: 1211 VYSFGMVCYEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPL 1270 Query: 476 ERPDFSEILEALK 438 +RP F+ I + LK Sbjct: 1271 KRPSFAVICQKLK 1283
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 60.1 bits (144), Expect = 6e-09 Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLT-PLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 VFS+GI+LWE++T + P++ + P + V G RP + KN + L+ +CW +DP Sbjct: 212 VFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDP 271 Query: 479 AERPDFSEILEAL 441 ++RP EI++ + Sbjct: 272 SQRPSMEEIVKIM 284
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 60.1 bits (144), Expect = 6e-09 Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGI++WE++ G+ PY ++ Q + V+ G R P+N L L+ CWQ+DP Sbjct: 829 VWSFGIIMWEVMAFGERPYWDMSG-QDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDP 887 Query: 479 AERPDFSEILEALKKIAEE 423 ERP FS+I L K+ ++ Sbjct: 888 GERPRFSQIHSILSKMVQD 906
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 60.1 bits (144), Expect = 6e-09 Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLT-PLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 VFS+GI+LWE++T + P++ + P + V G RP + KN + L+ +CW +DP Sbjct: 212 VFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDP 271 Query: 479 AERPDFSEILEAL 441 ++RP EI++ + Sbjct: 272 SQRPSMEEIVKIM 284
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 60.1 bits (144), Expect = 6e-09 Identities = 30/78 (38%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ + GKIPYE + + V + G R P+ A + +++ CW++ P Sbjct: 546 VWSFGVLMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASCHVYQIMNHCWKEKP 604 Query: 479 AERPDFSEILEALKKIAE 426 +RP FS++L L +IAE Sbjct: 605 EDRPPFSQLLSQLAEIAE 622
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 59.7 bits (143), Expect = 7e-09 Identities = 33/89 (37%), Positives = 52/89 (58%), Gaps = 7/89 (7%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+LLWE+ T G PY + L +++KG R P+ K+ EL++ CW+ P Sbjct: 468 VWAFGVLLWEIATYGMSPYPGID-LSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSP 526 Query: 479 AERPDFSEILEALK------KIAEEVGDE 411 A+RP F+E +A + I+EEV +E Sbjct: 527 ADRPSFAETHQAFETMFHDSSISEEVAEE 555
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 59.3 bits (142), Expect = 1e-08 Identities = 27/69 (39%), Positives = 40/69 (57%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SFG++LWELLTG+IPY+ + GV L +P + LL++CW + P Sbjct: 326 IWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPR 385 Query: 476 ERPDFSEIL 450 RP F +IL Sbjct: 386 NRPSFRQIL 394
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/79 (36%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ T G PY L +++G R P +A ++ E++QKCW++ Sbjct: 885 VWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKF 944 Query: 479 AERPDFSEILEALKKIAEE 423 RP FS+++ L+++ E Sbjct: 945 ETRPPFSQLVLLLERLLGE 963
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 58.9 bits (141), Expect = 1e-08 Identities = 27/69 (39%), Positives = 39/69 (56%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SFG++LWELLTG+IPY+ + GV L +P + LL++CW P Sbjct: 326 IWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPR 385 Query: 476 ERPDFSEIL 450 RP F +IL Sbjct: 386 NRPSFRQIL 394
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 58.9 bits (141), Expect = 1e-08 Identities = 27/69 (39%), Positives = 39/69 (56%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SFG++LWELLTG+IPY+ + GV L +P + LL++CW P Sbjct: 293 IWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPR 352 Query: 476 ERPDFSEIL 450 RP F +IL Sbjct: 353 NRPSFRQIL 361
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWELLT G PY ++ P + Q G R P+ L +++Q+CW+ DP Sbjct: 1270 VWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQ-GRRLPQPEYCPDSLYQVMQQCWEADP 1328 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 A RP F ++ +++I + +H Sbjct: 1329 AVRPTFRVLVGEVEQIVSALLGDH 1352
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ T G PY L + +++G R P +A ++ E++QKCW++ Sbjct: 886 VWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKF 945 Query: 479 AERPDFSEILEALKKIAEE 423 RP FS+++ L+++ E Sbjct: 946 EIRPPFSQLVLLLERLLGE 964
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ T G PY L + +++G R P +A ++ E++QKCW++ Sbjct: 886 VWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKF 945 Query: 479 AERPDFSEILEALKKIAEE 423 RP FS+++ L+++ E Sbjct: 946 EIRPPFSQLVLLLERLLGE 964
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/79 (36%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ T G PY L +++G R P +A ++ E++QKCW++ Sbjct: 885 VWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKF 944 Query: 479 AERPDFSEILEALKKIAEE 423 RP FS+++ L+++ E Sbjct: 945 ETRPPFSQLVLLLERLLGE 963
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/78 (37%), Positives = 49/78 (62%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T G++P+E T + V +V +G R PK A + E++ +CWQ+ P Sbjct: 548 VWSFGVLMWEVFTEGRMPFEKYTNYEV-VTMVTRGHRLYQPKLASNYVYEVMLRCWQEKP 606 Query: 479 AERPDFSEILEALKKIAE 426 RP F ++L + ++ E Sbjct: 607 EGRPSFEDLLRTIDELVE 624
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/78 (38%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ + GKIPYE + + V + G R P+ A + +++ CW++ P Sbjct: 541 VWSFGVLMWEVFSEGKIPYENRSNSEV-VEDISTGFRLYKPRLASTHVYQIMNHCWKERP 599 Query: 479 AERPDFSEILEALKKIAE 426 +RP FS +L L +IAE Sbjct: 600 EDRPAFSRLLRQLAEIAE 617
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/85 (38%), Positives = 50/85 (58%), Gaps = 2/85 (2%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWELLT G PY ++ P + + Q G R P+ L ++ +CW+ DP Sbjct: 1247 VWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQ-GRRLPQPEYCPDSLYHVMLRCWEADP 1305 Query: 479 AERPDF-SEILEALKKIAEEVGDEH 408 A RP F + +LE + +A +GD + Sbjct: 1306 AARPTFRALVLEVKQVVASLLGDHY 1330
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/85 (36%), Positives = 52/85 (61%), Gaps = 3/85 (3%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ +P Sbjct: 308 VWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNP 366 Query: 479 AERPDFSEILEALKKIAEE--VGDE 411 ++RP F+EI +A + + +E + DE Sbjct: 367 SDRPSFAEIHQAFETMFQESSISDE 391
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/85 (36%), Positives = 52/85 (61%), Gaps = 3/85 (3%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ +P Sbjct: 422 VWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNP 480 Query: 479 AERPDFSEILEALKKIAEE--VGDE 411 ++RP F+EI +A + + +E + DE Sbjct: 481 SDRPSFAEIHQAFETMFQESSISDE 505
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/85 (36%), Positives = 52/85 (61%), Gaps = 3/85 (3%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ +P Sbjct: 422 VWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNP 480 Query: 479 AERPDFSEILEALKKIAEE--VGDE 411 ++RP F+EI +A + + +E + DE Sbjct: 481 SDRPSFAEIHQAFETMFQESSISDE 505
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 58.2 bits (139), Expect = 2e-08 Identities = 30/76 (39%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ + G++PY + PL+ V V+KG + P + E+++ CW D Sbjct: 369 VWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDA 427 Query: 479 AERPDFSEILEALKKI 432 A RP F ++ E L+ I Sbjct: 428 AMRPSFLQLREQLEHI 443
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 57.8 bits (138), Expect = 3e-08 Identities = 26/79 (32%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW DP Sbjct: 854 VWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADP 913 Query: 479 AERPDFSEILEALKKIAEE 423 +RP F +I++ ++K E Sbjct: 914 LKRPTFKQIVQLIEKQISE 932
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 57.8 bits (138), Expect = 3e-08 Identities = 26/79 (32%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW DP Sbjct: 852 VWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADP 911 Query: 479 AERPDFSEILEALKKIAEE 423 +RP F +I++ ++K E Sbjct: 912 LKRPTFKQIVQLIEKQISE 930
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 57.8 bits (138), Expect = 3e-08 Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G+ PY ++ L+ V+KG R P + L+ CW+ +P Sbjct: 405 VWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEP 463 Query: 479 AERPDFSEILEALKKIAEEVG 417 A RP F +I+E L + VG Sbjct: 464 ARRPPFRKIVEKLGRELRSVG 484
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 57.8 bits (138), Expect = 3e-08 Identities = 26/79 (32%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW DP Sbjct: 853 VWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADP 912 Query: 479 AERPDFSEILEALKKIAEE 423 +RP F +I++ ++K E Sbjct: 913 LKRPTFKQIVQLIEKQISE 931
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 57.4 bits (137), Expect = 4e-08 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G PY +T QA V ++G R + P+N ++ ++ KCW P Sbjct: 244 VWSFGILLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQNCPEEIFTIMMKCWDYKP 302 Query: 479 AERPDFSEILEALKKIAEEV 420 RP FS++ + L I +++ Sbjct: 303 ENRPKFSDLHKELTAIKKKI 322
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 57.4 bits (137), Expect = 4e-08 Identities = 25/75 (33%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW DP Sbjct: 853 VWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADP 912 Query: 479 AERPDFSEILEALKK 435 +RP F +I++ ++K Sbjct: 913 LKRPTFKQIVQLIEK 927
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 57.4 bits (137), Expect = 4e-08 Identities = 25/75 (33%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW DP Sbjct: 290 VWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADP 349 Query: 479 AERPDFSEILEALKK 435 +RP F +I++ ++K Sbjct: 350 LKRPTFKQIVQLIEK 364
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 57.4 bits (137), Expect = 4e-08 Identities = 25/75 (33%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW DP Sbjct: 851 VWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADP 910 Query: 479 AERPDFSEILEALKK 435 +RP F +I++ ++K Sbjct: 911 LKRPTFKQIVQLIEK 925
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 57.4 bits (137), Expect = 4e-08 Identities = 32/91 (35%), Positives = 55/91 (60%), Gaps = 1/91 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL E++T G+IPY +T + + +++G R P N +L EL+ +CW++ P Sbjct: 421 VWSFGILLTEIVTYGRIPYPGMTNPEV-IQNLERGYRMPQPDNCPQELYELMMQCWKEQP 479 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKHKDK 387 ERP F E +K + E+ +G+++ + Sbjct: 480 EERPTF----EYMKSVLEDFFTATEGQYQQQ 506
>BTK_CHICK (Q8JH64) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) Length = 657 Score = 57.4 bits (137), Expect = 4e-08 Identities = 29/79 (36%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ + GK+PYE + V+Q GLR P+ A ++ ++ CW + Sbjct: 578 VWSFGVLMWEVYSLGKMPYERFNNSETTEHVIQ-GLRLYRPQQASERVYAIMYSCWHEKA 636 Query: 479 AERPDFSEILEALKKIAEE 423 ERP FS +L ++ I +E Sbjct: 637 EERPTFSALLGSIVDITDE 655
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 57.0 bits (136), Expect = 5e-08 Identities = 24/75 (32%), Positives = 47/75 (62%), Gaps = 1/75 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI LWEL + G PY + ++++G R P++A A++ ++++ CW DP Sbjct: 850 VWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADP 909 Query: 479 AERPDFSEILEALKK 435 +RP F ++++ ++K Sbjct: 910 LKRPTFKQVVQLIEK 924
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/79 (39%), Positives = 50/79 (63%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+++ G PY +T + + G R P N ++ EL+Q+CW++ P Sbjct: 1013 VWSYGVLLWEVVSLGGTPYCGMTCAEL-YEKLPLGFRLEKPLNCDDEVYELMQQCWREKP 1071 Query: 479 AERPDFSEILEALKKIAEE 423 ERP FS+IL +L ++ EE Sbjct: 1072 FERPSFSQILLSLGRMLEE 1090
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 57.0 bits (136), Expect = 5e-08 Identities = 29/78 (37%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T G++P+E T + V +V +G R PK A L E++ +CWQ+ P Sbjct: 547 VWSFGVLMWEIFTEGRMPFEKNTNYEV-VTMVTRGHRLHRPKLATKYLYEVMLRCWQERP 605 Query: 479 AERPDFSEILEALKKIAE 426 RP ++L + ++ E Sbjct: 606 EGRPSLEDLLRTIDELVE 623
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 57.0 bits (136), Expect = 5e-08 Identities = 29/76 (38%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ + G++PY + PL+ V V+KG + P + ++++ CW D Sbjct: 369 VWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDA 427 Query: 479 AERPDFSEILEALKKI 432 A RP F ++ E L+ I Sbjct: 428 ATRPTFLQLREQLEHI 443
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 57.0 bits (136), Expect = 5e-08 Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 ++SFGIL+WE++T G PY ++ + V+ G R P++ +L ++ CW DP Sbjct: 670 IWSFGILMWEIVTLGSTPYPGISAADV-MRKVRDGYRLEKPEHCRRELYNIMYYCWSHDP 728 Query: 479 AERPDFSEILEALKKI 432 ERP F+EI++ L K+ Sbjct: 729 QERPLFAEIIQMLDKL 744
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G+ PY ++ L+ V+KG R P + + L+ CW+ +P Sbjct: 367 VWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEP 425 Query: 479 AERPDFSEILEALKKIAEEVG 417 + RP F +I+E L + VG Sbjct: 426 SRRPPFRKIVEKLGRELRSVG 446
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 56.6 bits (135), Expect = 6e-08 Identities = 30/85 (35%), Positives = 52/85 (61%), Gaps = 1/85 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE++T G PY + P + +++ G R P N ++ L+ +CW+Q+P Sbjct: 935 VWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEP 993 Query: 479 AERPDFSEILEALKKIAEEVGDEHD 405 +RP F++I + L+K+ + D D Sbjct: 994 DKRPVFADISKDLEKMMVKSRDYLD 1018
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 56.6 bits (135), Expect = 6e-08 Identities = 32/72 (44%), Positives = 48/72 (66%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V++G R P++ A L EL+ +CW++DP Sbjct: 448 VWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPASLHELMLQCWKKDP 506 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 507 EERPTF-EYLQA 517
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/75 (38%), Positives = 48/75 (64%), Gaps = 1/75 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE++T + PY+ L+ Q V+ G+ + H +L EL+ CWQQ+P Sbjct: 1175 VWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPH-QLQELMSSCWQQNP 1233 Query: 479 AERPDFSEILEALKK 435 RP F++IL +++K Sbjct: 1234 RLRPTFTQILNSIQK 1248
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 56.2 bits (134), Expect = 8e-08 Identities = 28/87 (32%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+ + G PY + + +++G+R P+ A ++ +++ CW +DP Sbjct: 1082 VWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDP 1141 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGK 399 ERP F+E++E L + + + DGK Sbjct: 1142 KERPRFAELVEKLGDLL-QANVQQDGK 1167
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 56.2 bits (134), Expect = 8e-08 Identities = 28/76 (36%), Positives = 49/76 (64%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE++T G PY + P + +++ G R P N ++ L+ +CW+Q+P Sbjct: 934 VWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEP 992 Query: 479 AERPDFSEILEALKKI 432 +RP F++I + L+K+ Sbjct: 993 DKRPVFADISKDLEKM 1008
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 56.2 bits (134), Expect = 8e-08 Identities = 28/87 (32%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+ + G PY + + +++G+R P+ A ++ +++ CW +DP Sbjct: 1082 VWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDP 1141 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGK 399 ERP F+E++E L + + + DGK Sbjct: 1142 KERPRFAELVEKLGDLL-QANVQQDGK 1167
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/79 (36%), Positives = 51/79 (64%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+++ G PY +T + + Q G R P N ++ +L+++CW++ P Sbjct: 1021 VWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWREKP 1079 Query: 479 AERPDFSEILEALKKIAEE 423 ERP F++IL +L ++ EE Sbjct: 1080 YERPSFAQILVSLNRMLEE 1098
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 56.2 bits (134), Expect = 8e-08 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G PY +T QA V ++G R + P++ +++++ KCW P Sbjct: 743 VWSFGILLWETFSLGVCPYPGMTNQQAREQV-ERGYRMSAPQHCPEDISKIMMKCWDYKP 801 Query: 479 AERPDFSEILEALKKIAEEV 420 RP FSE+ + L I ++ Sbjct: 802 ENRPKFSELQKELTIIKRKL 821
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/79 (36%), Positives = 51/79 (64%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+++ G PY +T + + Q G R P N ++ +L+++CW++ P Sbjct: 1019 VWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWREKP 1077 Query: 479 AERPDFSEILEALKKIAEE 423 ERP F++IL +L ++ EE Sbjct: 1078 YERPSFAQILVSLNRMLEE 1096
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/79 (36%), Positives = 51/79 (64%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+++ G PY +T + + Q G R P N ++ +L+++CW++ P Sbjct: 1022 VWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRLEKPLNCDDEVYDLMRQCWREKP 1080 Query: 479 AERPDFSEILEALKKIAEE 423 ERP F++IL +L ++ EE Sbjct: 1081 YERPSFAQILVSLNRMLEE 1099
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 55.8 bits (133), Expect = 1e-07 Identities = 29/81 (35%), Positives = 48/81 (59%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI+LWE+++ G+ PY ++ Q + V +G R +P + A L +L+ CWQ+D Sbjct: 808 VWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDR 866 Query: 479 AERPDFSEILEALKKIAEEVG 417 RP F +I+ L K+ G Sbjct: 867 NNRPKFEQIVSILDKLIRNPG 887
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 55.8 bits (133), Expect = 1e-07 Identities = 29/76 (38%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ+D Sbjct: 837 VWSYGIVMWEVMSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDR 895 Query: 479 AERPDFSEILEALKKI 432 RP F EI+ L K+ Sbjct: 896 NSRPKFDEIVSMLDKL 911
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 55.8 bits (133), Expect = 1e-07 Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G+ PY ++ L+ V+KG R P+ + L+ CW+ +P Sbjct: 407 VWSFGVLLWEVFSYGRAPYPKMS-LKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEP 465 Query: 479 AERPDFSEILEALKKIAEEVG 417 A RP F ++ E L + G Sbjct: 466 ARRPPFRKLAEKLARELRSAG 486
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/78 (39%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ +P Sbjct: 1195 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNP 1253 Query: 479 AERPDFSEILEALKKIAE 426 RP F EI+ ++K+ E Sbjct: 1254 KMRPSFLEIISSIKEEME 1271
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/82 (32%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+++G+L+WE+ T GK+PY L + V VQ+G+ PK+ ++ ++++ CW P Sbjct: 706 VWAYGVLMWEIFTCGKMPYGRLKNTEV-VERVQRGIILEKPKSCAKEIYDVMKLCWSHGP 764 Query: 479 AERPDFSEILEALKKIAEEVGD 414 ERP F +++ L +A+ + D Sbjct: 765 EERPAFRVLMDQLALVAQTLTD 786
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/76 (35%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CWQ P Sbjct: 688 VWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVP 746 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L +I Sbjct: 747 SQRPTFKQLVEDLDRI 762
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/76 (35%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGI++WE++T G+ PY L+ + + + G R P + + + +L+ +CWQQ+ Sbjct: 800 VWSFGIVMWEVMTYGERPYWELSNHEV-MKAINDGFRLPTPMDCPSAIYQLMMQCWQQER 858 Query: 479 AERPDFSEILEALKKI 432 A RP F++I+ L K+ Sbjct: 859 ARRPKFADIVSILDKL 874
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/76 (38%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ+D Sbjct: 700 VWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDR 758 Query: 479 AERPDFSEILEALKKI 432 RP F EI+ L K+ Sbjct: 759 NSRPKFDEIVNMLDKL 774
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 55.5 bits (132), Expect = 1e-07 Identities = 28/76 (36%), Positives = 49/76 (64%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ+D Sbjct: 819 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDR 877 Query: 479 AERPDFSEILEALKKI 432 AERP F +I+ L K+ Sbjct: 878 AERPKFEQIVGILDKM 893
>RYK_HUMAN (P34925) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| Length = 604 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+ LWEL+T G+ PY + P + A ++ G R P N +L ++ CW DP Sbjct: 522 VWAFGVTLWELMTLGQTPYVDIDPFEMAA-YLKDGYRIAQPINCPDELFAVMACCWALDP 580 Query: 479 AERPDFSEILEALKKIAEEVG 417 ERP F ++++ L + +G Sbjct: 581 EERPKFQQLVQCLTEFHAALG 601
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/87 (31%), Positives = 52/87 (59%), Gaps = 1/87 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+ + G PY + + +++G+R P+ + ++ +++ CW +DP Sbjct: 1082 VWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDP 1141 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGK 399 ERP F+E++E L + + + DGK Sbjct: 1142 KERPRFAELVEKLGDLL-QANVQQDGK 1167
>RYK_MOUSE (Q01887) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| (Kinase VIK) (NYK-R) (Met-related kinase) Length = 594 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+ LWEL+T G+ PY + P + A ++ G R P N +L ++ CW DP Sbjct: 512 VWAFGVTLWELMTLGQTPYVDIDPFEMAA-YLKDGYRIAQPINCPDELFAVMACCWALDP 570 Query: 479 AERPDFSEILEALKKIAEEVG 417 ERP F ++++ L + +G Sbjct: 571 EERPKFQQLVQCLTEFHAALG 591
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/78 (38%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+++ G PY +T + + Q G R P+N ++ EL+++CW+ P Sbjct: 82 VWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRDRP 140 Query: 479 AERPDFSEILEALKKIAE 426 ERP FS+I L ++ E Sbjct: 141 YERPPFSQISVQLNRMQE 158
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 55.1 bits (131), Expect = 2e-07 Identities = 27/76 (35%), Positives = 49/76 (64%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ++ Sbjct: 190 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKER 248 Query: 479 AERPDFSEILEALKKI 432 AERP FS+I+ L K+ Sbjct: 249 AERPKFSQIVNMLDKL 264
>RYK1_DROME (Q27324) Tyrosine-protein kinase Drl precursor (EC 2.7.10.1)| (Protein derailed) Length = 610 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T GK+PY + P + ++ G R P N +L ++ CW P Sbjct: 528 VWSFGVLMWEMCTLGKLPYAEIDPYEME-HYLKDGYRLAQPFNCPDELFTIMAYCWASMP 586 Query: 479 AERPDFSEILEALKKIAEEV 420 AERP FS++ L + ++ Sbjct: 587 AERPSFSQLQICLSEFHTQI 606
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ +P Sbjct: 468 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNP 526 Query: 479 AERPDFSEILEALK 438 RP F EI+ ++K Sbjct: 527 KMRPSFLEIISSVK 540
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 54.7 bits (130), Expect = 2e-07 Identities = 29/69 (42%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G+IPY +T + V + G R P N +L E++ +CW +DP Sbjct: 429 VWSFGILLTELVTYGRIPYPGMTNAEVLTQV-EHGYRMPQPPNCEPRLYEIMLECWHKDP 487 Query: 479 AERPDFSEI 453 RP F + Sbjct: 488 MRRPTFETL 496
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 54.7 bits (130), Expect = 2e-07 Identities = 27/76 (35%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW P Sbjct: 677 VWSFGVLLWEIFTLGGSPYPGV-PMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAMP 735 Query: 479 AERPDFSEILEALKKI 432 ++RP F++++E L +I Sbjct: 736 SQRPTFNQLVEDLDRI 751
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 54.3 bits (129), Expect = 3e-07 Identities = 26/76 (34%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ T G PY + P++ ++++G R P N L ++++CW P Sbjct: 677 VWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAP 735 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L ++ Sbjct: 736 SQRPTFKQLVEDLDRV 751
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ +P Sbjct: 1196 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNP 1254 Query: 479 AERPDFSEILEALK 438 RP F EI+ ++K Sbjct: 1255 KMRPSFLEIIGSIK 1268
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/76 (35%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW P Sbjct: 681 VWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVP 739 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L +I Sbjct: 740 SQRPTFKQLVEDLDRI 755
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 7/75 (9%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTI-------PKNAHAKLTELLQK 498 V+SF I++WE+LT K PY L + + V G+RP++ P+ H ++ L+++ Sbjct: 221 VYSFAIVIWEILTQKKPYAGLNMMTIIIRVA-AGMRPSLQDVSDEWPEEVH-QMVNLMKR 278 Query: 497 CWQQDPAERPDFSEI 453 CW QDP +RP F + Sbjct: 279 CWDQDPKKRPCFLNV 293
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V++G R P+ L EL++ CW++DP Sbjct: 452 VWSFGILLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWKKDP 510 Query: 479 AERPDFSEILEALK 438 ERP F I L+ Sbjct: 511 DERPTFEYIQSFLE 524
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 54.3 bits (129), Expect = 3e-07 Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 7/75 (9%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTI-------PKNAHAKLTELLQK 498 V+SF I++WELLT K PY + + V G+RP++ P A ++ +L+++ Sbjct: 209 VYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA-GMRPSLQPVSDQWPSEAQ-QMVDLMKR 266 Query: 497 CWQQDPAERPDFSEI 453 CW QDP +RP F +I Sbjct: 267 CWDQDPKKRPCFLDI 281
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/76 (35%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW P Sbjct: 683 VWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVP 741 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L +I Sbjct: 742 SQRPTFKQLVEDLDRI 757
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/76 (35%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ T G PY + P++ ++++G R P N +L +++ CW P Sbjct: 683 VWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVP 741 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L +I Sbjct: 742 SQRPTFKQLVEDLDRI 757
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 54.3 bits (129), Expect = 3e-07 Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ+D Sbjct: 863 VWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDR 921 Query: 479 AERPDFSEILEALKKI 432 RP F +I+ L K+ Sbjct: 922 NSRPKFDDIVNMLDKL 937
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/73 (39%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 VFS+G++LWE+ T PY+ LT Q V+ G+ P+N L L+++CWQ P Sbjct: 1222 VFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMER-PENCPDNLYNLMRRCWQHRP 1280 Query: 479 AERPDFSEILEAL 441 RP F EI+ L Sbjct: 1281 TARPTFMEIISEL 1293
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/79 (34%), Positives = 41/79 (51%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SFG++LWELLTG+IPY+ + GV L +P L+++ WQ P Sbjct: 336 IWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPR 395 Query: 476 ERPDFSEILEALKKIAEEV 420 RP F + L L + +V Sbjct: 396 NRPSFRQTLMHLDIASADV 414
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/79 (34%), Positives = 41/79 (51%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 ++SFG++LWELLTG+IPY+ + GV L +P L+++ WQ P Sbjct: 336 IWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPR 395 Query: 476 ERPDFSEILEALKKIAEEV 420 RP F + L L + +V Sbjct: 396 NRPSFRQTLMHLDIASADV 414
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE+ T + PY+ L+ Q V++ GL P N L EL++ CWQ +P Sbjct: 1197 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNP 1255 Query: 479 AERPDFSEILEALK 438 RP F EI+ ++K Sbjct: 1256 KMRPSFLEIIGSIK 1269
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V++G R P+ L EL++ CW++DP Sbjct: 445 VWSFGILLTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMKLCWKKDP 503 Query: 479 AERPDFSEILEALK 438 ERP F I L+ Sbjct: 504 DERPTFEYIQSFLE 517
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/76 (34%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ T G PY + P++ ++++G R P N L ++++CW P Sbjct: 671 VWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVP 729 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L ++ Sbjct: 730 SQRPTFKQLVEDLDRV 745
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/74 (41%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGIL+WE+LT G PY + L + VQ G R P+N L L+ +CW Q+P Sbjct: 2144 VWSFGILIWEILTLGHQPYPAHSNLDV-LNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEP 2202 Query: 479 AERPDFSEILEALK 438 +RP F I L+ Sbjct: 2203 DQRPTFHRIQNQLQ 2216
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 53.9 bits (128), Expect = 4e-07 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI+LWE+++ G+ PY ++ Q + V +G R P + A L +L+ CWQ+D Sbjct: 807 VWSYGIVLWEVMSYGERPYWEMSN-QDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDR 865 Query: 479 AERPDFSEILEALKKIAEEVG 417 RP F +I+ L K+ G Sbjct: 866 NNRPKFEQIVSILDKLIRNPG 886
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/76 (36%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY +T Q + V++G R P + A L +L+ CWQ++ Sbjct: 861 VWSYGIVMWEVVSYGERPYWEMTN-QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKER 919 Query: 479 AERPDFSEILEALKKI 432 RP F EI+ L K+ Sbjct: 920 NSRPKFDEIVNMLDKL 935
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G +PY L+ Q + Q G+R P+ + L+Q+CW+ DP Sbjct: 454 VWSFGILLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQRCWEYDP 512 Query: 479 AERPDFSEILEAL 441 RP F + + L Sbjct: 513 RRRPSFGAVHQDL 525
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/76 (35%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+++WE+L G+ PY +T Q + V++G R P L +L+ CW +D Sbjct: 188 VWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDR 246 Query: 479 AERPDFSEILEALKKI 432 A+RP FS ++ L+ + Sbjct: 247 AQRPRFSHVVSVLEAL 262
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/76 (35%), Positives = 49/76 (64%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ++ Sbjct: 819 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKER 877 Query: 479 AERPDFSEILEALKKI 432 AERP F +I+ L K+ Sbjct: 878 AERPKFEQIVGILDKM 893
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/76 (35%), Positives = 49/76 (64%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ++ Sbjct: 819 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKER 877 Query: 479 AERPDFSEILEALKKI 432 AERP F +I+ L K+ Sbjct: 878 AERPKFEQIVGILDKM 893
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 +++FG+L+WE+ + GK+PYE T + A + Q GLR P A K+ ++ CW + Sbjct: 579 IWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASEKVYTIMYSCWHEKA 637 Query: 479 AERPDFSEILEALKKIAEE 423 ERP F +L + + +E Sbjct: 638 DERPTFKILLSNILDVMDE 656
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 53.5 bits (127), Expect = 5e-07 Identities = 26/76 (34%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CW P Sbjct: 686 VWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVP 744 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L +I Sbjct: 745 SQRPTFKQLVEDLDRI 760
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 53.5 bits (127), Expect = 5e-07 Identities = 26/76 (34%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CW P Sbjct: 686 VWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVP 744 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L +I Sbjct: 745 SQRPTFKQLVEDLDRI 760
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW DP Sbjct: 605 VWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDP 663 Query: 479 AERPDFSEILEALKKIAEE 423 + RP F+E+ L I EE Sbjct: 664 SRRPRFTELKAQLSTILEE 682
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW DP Sbjct: 643 VWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDP 701 Query: 479 AERPDFSEILEALKKIAEE 423 + RP F+E+ L I EE Sbjct: 702 SRRPRFTELKAQLSTILEE 720
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW DP Sbjct: 605 VWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDP 663 Query: 479 AERPDFSEILEALKKIAEE 423 + RP F+E+ L I EE Sbjct: 664 SRRPRFTELKAQLSTILEE 682
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -3 Query: 653 FSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 +SFG+LLWE+ + G +PY T Q + + G R P+N + ++ +CWQ P Sbjct: 703 WSFGVLLWEIFSLGYMPYPGHTN-QEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQHQPE 761 Query: 476 ERPDFSEILEALKKIAEE 423 RPDF ILE ++ ++ Sbjct: 762 LRPDFGSILERIQYCTQD 779
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 53.5 bits (127), Expect = 5e-07 Identities = 27/69 (39%), Positives = 43/69 (62%), Gaps = 1/69 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+LLWE+ T G PY + L +++K R P+ K+ EL++ CWQ +P Sbjct: 371 VWAFGVLLWEIATYGMSPYPGID-LSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNP 429 Query: 479 AERPDFSEI 453 ++RP F+EI Sbjct: 430 SDRPAFAEI 438
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/66 (42%), Positives = 42/66 (63%), Gaps = 1/66 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++DP Sbjct: 448 VWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMLNCWKKDP 506 Query: 479 AERPDF 462 ERP F Sbjct: 507 EERPTF 512
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G +PY L+ Q + Q G+R P+ + L+Q+CW+ DP Sbjct: 794 VWSFGILLWEAFSLGAVPYANLSNQQTREAIEQ-GVRLEPPEQCPEDVYRLMQRCWEYDP 852 Query: 479 AERPDFSEILEAL 441 RP F + + L Sbjct: 853 HRRPSFGAVHQDL 865
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW DP Sbjct: 618 VWMFGVCMWEILMYGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDP 676 Query: 479 AERPDFSEILEALKKIAEE 423 + RP F+E+ L I EE Sbjct: 677 SRRPRFTELKAQLSTILEE 695
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ FG+ +WE+L G P++ + +G ++ G R +P N L L+ KCW DP Sbjct: 605 VWMFGVCMWEILMHGVKPFQGVKN-NDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDP 663 Query: 479 AERPDFSEILEALKKIAEE 423 + RP F+E+ L I EE Sbjct: 664 SRRPRFTELKAQLSTILEE 682
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 53.5 bits (127), Expect = 5e-07 Identities = 29/74 (39%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE+ T + PY+ ++ Q V++ GL P N L EL++ CWQ +P Sbjct: 1191 VWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEK-PDNCPDMLFELMRMCWQFNP 1249 Query: 479 AERPDFSEILEALK 438 RP F EI+ ++K Sbjct: 1250 KMRPSFLEIISSIK 1263
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 53.5 bits (127), Expect = 5e-07 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G PY + + +++G R P ++ + + CW +DP Sbjct: 1086 VWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDP 1145 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGK 399 +RP FSE++E L + + + DGK Sbjct: 1146 NQRPSFSELVEHLGNLL-QANAQQDGK 1171
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 53.1 bits (126), Expect = 7e-07 Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+L+WE LT G+ PY L+ ++ + V+ G R P N + +L+ +CW QDP Sbjct: 2161 VWAFGVLVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDP 2219 Query: 479 AERPDFSEILEALKKI 432 RP F I L++I Sbjct: 2220 HNRPTFFYIQHKLQEI 2235
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 53.1 bits (126), Expect = 7e-07 Identities = 29/78 (37%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+++ G PY +T + + Q G R P+N ++ EL+++CW+ P Sbjct: 1032 VWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRDRP 1090 Query: 479 AERPDFSEILEALKKIAE 426 ERP F++I L ++ E Sbjct: 1091 YERPPFAQIALQLGRMLE 1108
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 53.1 bits (126), Expect = 7e-07 Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+L+WE LT G+ PY L+ ++ + V+ G R P N + +L+ +CW QDP Sbjct: 298 VWAFGVLVWETLTLGQQPYPGLSNIEV-LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDP 356 Query: 479 AERPDFSEILEALKKI 432 RP F I L++I Sbjct: 357 HNRPTFFYIQHKLQEI 372
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G PY LT Q V+KG R P+ + L+++CW +P Sbjct: 741 VWSFGILLWETFSLGASPYPNLTNQQTRE-FVEKGHRLPCPELCPDAVFRLMEQCWAYEP 799 Query: 479 AERPDFSEILEALKKI 432 +RP FS I + L I Sbjct: 800 GQRPSFSIICQELHSI 815
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 53.1 bits (126), Expect = 7e-07 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -3 Query: 653 FSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 +SFG+LLWE+ + G +PY + Q + V G R PKN + ++ +CWQ P Sbjct: 1313 WSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPE 1371 Query: 476 ERPDFSEILEALKKIAEE 423 +RP+F+ ILE ++ ++ Sbjct: 1372 DRPNFAIILERIEYCTQD 1389
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 53.1 bits (126), Expect = 7e-07 Identities = 29/74 (39%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++DP Sbjct: 448 VWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKKDP 506 Query: 479 AERPDFSEILEALK 438 ERP F + L+ Sbjct: 507 EERPTFEYLQSFLE 520
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 53.1 bits (126), Expect = 7e-07 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -3 Query: 653 FSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 +SFG+LLWE+ + G +PY + Q + V G R PKN + ++ +CWQ P Sbjct: 1317 WSFGVLLWEIFSLGYMPYPSKSN-QEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPE 1375 Query: 476 ERPDFSEILEALKKIAEE 423 +RP+F+ ILE ++ ++ Sbjct: 1376 DRPNFAIILERIEYCTQD 1393
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 53.1 bits (126), Expect = 7e-07 Identities = 26/88 (29%), Positives = 52/88 (59%), Gaps = 1/88 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ + G PY L + +++G R P+ + +++ + + CW +P Sbjct: 1063 VWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEP 1122 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKH 396 ++RP F+E++E L + + + +GKH Sbjct: 1123 SQRPTFTELVERLGDLL-QASVQQEGKH 1149
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 53.1 bits (126), Expect = 7e-07 Identities = 29/78 (37%), Positives = 48/78 (61%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+++ G PY +T + + Q G R P+N ++ EL+++CW+ P Sbjct: 1036 VWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-GYRMEQPRNCDDEVYELMRQCWRDRP 1094 Query: 479 AERPDFSEILEALKKIAE 426 ERP F++I L ++ E Sbjct: 1095 YERPPFAQIALQLGRMLE 1112
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 53.1 bits (126), Expect = 7e-07 Identities = 25/76 (32%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE++T G+ PY L+ + + + G R P + + + +L+ +CWQQ+ Sbjct: 801 VWSYGIVMWEVMTYGERPYWELSNHEV-MKAINDGFRLPTPMDCPSAIYQLMMQCWQQER 859 Query: 479 AERPDFSEILEALKKI 432 + RP F++I+ L K+ Sbjct: 860 SRRPKFADIVSILDKL 875
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 52.8 bits (125), Expect = 9e-07 Identities = 26/79 (32%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 +++FG+L+WE+ + GK+PYE T + A + Q GLR P A ++ ++ CW + Sbjct: 579 IWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQ-GLRLYRPHLASERVYTIMYSCWHEKA 637 Query: 479 AERPDFSEILEALKKIAEE 423 ERP F +L + + +E Sbjct: 638 DERPSFKILLSNILDVMDE 656
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 52.8 bits (125), Expect = 9e-07 Identities = 29/74 (39%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE+ + + PY+ L+ Q V+ G P+N +L L+Q CWQ +P Sbjct: 1208 VWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDH-PENCPPRLHSLMQMCWQYNP 1266 Query: 479 AERPDFSEILEALK 438 RP F EI++ LK Sbjct: 1267 KMRPTFLEIIDMLK 1280
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WELLT G PY + P A ++ +G R P+ L ++ CW P Sbjct: 248 VWSFGVLMWELLTRGASPYPEVDPYDMARYLL-RGRRLPQPQPCPDTLYGVMLSCWAPTP 306 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 ERP FS ++ L+++ + EH Sbjct: 307 EERPSFSGLVCELERVLASLEGEH 330
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 52.8 bits (125), Expect = 9e-07 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GILLWE++T G+ PY + + + G R P + L+++CW + Sbjct: 616 VWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNA 675 Query: 479 AERPDFSEILEALKKIAEEVGDEHD 405 +RP F+EI+E + K+ + D D Sbjct: 676 DDRPPFTEIVEYMDKLLQTKEDYLD 700
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW +P Sbjct: 741 VWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEP 799 Query: 479 AERPDFSEILEALKKI 432 +RP FS I + L+ I Sbjct: 800 GQRPSFSAIYQELQSI 815
>VGFR2_RAT (O08775) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) Length = 1343 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G PY + + +++G R P ++ + + CW +DP Sbjct: 1084 VWSFGVLLWEIFSLGASPYPGVKIDEKFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDP 1143 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGK 399 +RP FSE++E L + + + DGK Sbjct: 1144 NQRPAFSELVEHLGNLL-QANAQQDGK 1169
>PGFRA_HUMAN (P16234) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) (CD140a antigen) Length = 1089 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GILLWE+ + G PY + ++ G R P +A +++ E++ KCW +P Sbjct: 878 VWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEP 937 Query: 479 AERPDF---SEILEAL 441 +RP F SEI+E L Sbjct: 938 EKRPSFYHLSEIVENL 953
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 52.8 bits (125), Expect = 9e-07 Identities = 23/75 (30%), Positives = 46/75 (61%), Gaps = 1/75 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GILLWEL + G PY + ++++G R P+ + ++ ++++ CW DP Sbjct: 837 VWSYGILLWELFSLGSSPYPGMPVDSKFYKMIKEGYRMFSPECSPPEMYDIMKSCWDADP 896 Query: 479 AERPDFSEILEALKK 435 +RP F +I++ +++ Sbjct: 897 LQRPTFKQIVQLIEQ 911
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 52.8 bits (125), Expect = 9e-07 Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 1/89 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G PY + + ++ G R P+ A + ++Q CW DP Sbjct: 1097 VWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDP 1156 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKHK 393 RP FS+++E L + + G + + + + Sbjct: 1157 KARPAFSDLVEILGDLLQGGGWQEEEEER 1185
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW +P Sbjct: 743 VWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEP 801 Query: 479 AERPDFSEILEALKKI 432 +RP FS I + L+ I Sbjct: 802 GQRPSFSTIYQELQSI 817
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 52.8 bits (125), Expect = 9e-07 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+WE+ T G PY + P++ ++++G R P N +L +++ CW P Sbjct: 676 VWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAIP 734 Query: 479 AERPDFSEILEALKKI 432 + RP F +++E L +I Sbjct: 735 SHRPTFKQLVEDLDRI 750
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/66 (42%), Positives = 42/66 (63%), Gaps = 1/66 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++DP Sbjct: 445 VWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKKDP 503 Query: 479 AERPDF 462 ERP F Sbjct: 504 EERPTF 509
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 52.8 bits (125), Expect = 9e-07 Identities = 28/66 (42%), Positives = 42/66 (63%), Gaps = 1/66 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V++G R P++ L EL+ CW++DP Sbjct: 445 VWSFGILLTELVTKGRVPYPGMNNREV-LEQVERGYRMPCPQDCPISLHELMIHCWKKDP 503 Query: 479 AERPDF 462 ERP F Sbjct: 504 EERPTF 509
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW +P Sbjct: 530 VWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEP 588 Query: 479 AERPDFSEILEALKKI 432 +RP FS I + L+ I Sbjct: 589 GQRPSFSAIYQELQSI 604
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 52.4 bits (124), Expect = 1e-06 Identities = 26/75 (34%), Positives = 48/75 (64%), Gaps = 1/75 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE++T + PY+ L+ Q V+ G+ + + +L EL+ +CWQ +P Sbjct: 1175 VWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-EGCPLQLQELMSRCWQPNP 1233 Query: 479 AERPDFSEILEALKK 435 RP F+ IL+++++ Sbjct: 1234 RLRPSFTHILDSIQE 1248
>BMX_MOUSE (P97504) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein homolog) Length = 651 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FGIL+WE+ + GK PY+ + V V Q G R P+ A + +++ CW + P Sbjct: 571 VWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQ-GHRLYRPQLASDTIYQIMYSCWHELP 629 Query: 479 AERPDFSEILEALKKIAEE 423 +RP F ++L A++ + E+ Sbjct: 630 EKRPTFQQLLSAIEPLREQ 648
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL E++T G+IPY ++ + + +++G R P+N +L ++ +CW+ P Sbjct: 439 VWSFGILLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWKNRP 497 Query: 479 AERPDFSEILEAL 441 ERP F I L Sbjct: 498 EERPTFEYIQSVL 510
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI+LWE+++ G+ PY ++ Q + V + R P + A L +L+ CWQ+D Sbjct: 807 VWSYGIVLWEVMSYGERPYSQMSN-QDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDR 865 Query: 479 AERPDFSEILEALKKIAEEVG 417 RP F +I+ L K+ G Sbjct: 866 NNRPKFEQIVSILDKLIRNPG 886
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 52.4 bits (124), Expect = 1e-06 Identities = 26/76 (34%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + A L +L+ CWQ++ Sbjct: 814 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKER 872 Query: 479 AERPDFSEILEALKKI 432 ERP F +I+ L K+ Sbjct: 873 GERPKFEQIVGILDKM 888
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL E++T G+IPY ++ + + +++G R P+N +L ++ +CW+ P Sbjct: 417 VWSFGILLMEIVTYGRIPYPGMSNPEV-IRALERGYRMPRPENCPEELYNIMMRCWKNRP 475 Query: 479 AERPDFSEILEAL 441 ERP F I L Sbjct: 476 EERPTFEYIQSVL 488
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/74 (39%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+ G++PY + + + V++G R P+ L EL++ CW++DP Sbjct: 448 VWSFGILLTELVAKGRVPYPGMVNREV-LEQVERGYRMPCPQRCPESLHELMKLCWKKDP 506 Query: 479 AERPDFSEILEALK 438 ERP F I L+ Sbjct: 507 DERPTFEYIQSFLE 520
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G PY + + ++ G R P+ A + ++Q CW DP Sbjct: 1097 VWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDP 1156 Query: 479 AERPDFSEILEALKKIAEEVG 417 RP FS+++E L + + G Sbjct: 1157 KARPAFSDLVEILGDLLQGGG 1177
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 52.4 bits (124), Expect = 1e-06 Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+++WE+L G+ PY +T + + V++G R P L +L+ CW +D Sbjct: 821 VWSFGVVMWEVLAYGERPYWNMTN-RDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDR 879 Query: 479 AERPDFSEILEAL 441 A+RP FS+I+ L Sbjct: 880 AQRPRFSQIVSVL 892
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/74 (37%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL+T G++PY + + + V +G R P+ L E++++CW+++P Sbjct: 455 VWSFGILLTELVTKGRVPYPGMVNREV-LEQVDRGYRMPCPQGCPESLHEMMRQCWKKEP 513 Query: 479 AERPDFSEILEALK 438 ERP F I L+ Sbjct: 514 DERPTFEYIQSFLE 527
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 52.4 bits (124), Expect = 1e-06 Identities = 26/77 (33%), Positives = 47/77 (61%), Gaps = 2/77 (2%) Frame = -3 Query: 656 VFSFGILLWELLT--GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQD 483 V+SFG+LLWE+ T G PY + P++ ++++G R P + L ++++CW Sbjct: 671 VWSFGVLLWEIFTPGGPSPYPGI-PVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAV 729 Query: 482 PAERPDFSEILEALKKI 432 P++RP F +++E L +I Sbjct: 730 PSQRPTFKQLVEDLDRI 746
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 52.0 bits (123), Expect = 2e-06 Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 1/75 (1%) Frame = -3 Query: 653 FSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 +S+GI+LWE+++ G+ PY ++ Q + V +G R P + A L +L+ CWQ+D Sbjct: 808 WSYGIVLWEVMSYGERPYWEMS-FQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRN 866 Query: 476 ERPDFSEILEALKKI 432 RP F +I+ L K+ Sbjct: 867 NRPKFEQIVSILDKL 881
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/90 (35%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGI+L+E++T G+ PY +T Q + +Q+ R P KL ++ CW++DP Sbjct: 418 VWSFGIVLYEVITYGRFPYPGMTNAQV-LEQIQQSYRMPRPMGCPEKLYAIMMDCWREDP 476 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKHKD 390 A RP F + L++ GD D +KD Sbjct: 477 ASRPTFETLSWQLEEFF-TTGD--DAGYKD 503
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 52.0 bits (123), Expect = 2e-06 Identities = 28/79 (35%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+LLWE+ T G PY + L + KG R P ++ +L+++CWQ D Sbjct: 551 VWAFGVLLWEIATYGMSPYPAID-LTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDA 609 Query: 479 AERPDFSEILEALKKIAEE 423 +RP F I AL+ + +E Sbjct: 610 TDRPTFKSIHHALEHMFQE 628
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 52.0 bits (123), Expect = 2e-06 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+++WE+L G+ PY +T Q + V++G R P L +L+ CW +D Sbjct: 820 VWSFGVVMWEVLAYGERPYWNMTN-QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDR 878 Query: 479 AERPDFSEILEAL 441 A+RP F+ ++ L Sbjct: 879 AQRPRFAHVVSVL 891
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 52.0 bits (123), Expect = 2e-06 Identities = 25/76 (32%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ+D Sbjct: 806 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDR 864 Query: 479 AERPDFSEILEALKKI 432 ++RP F +I+ L K+ Sbjct: 865 SDRPKFGQIVSMLDKL 880
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/75 (40%), Positives = 46/75 (61%), Gaps = 2/75 (2%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKG-LRPTIPKNAHAKLTELLQKCWQQD 483 ++SFG++LWE+ + + PY+ L+ Q V+ G L P P N +LT+L++ CWQ + Sbjct: 1209 MWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP--PDNCPERLTDLMRMCWQFN 1266 Query: 482 PAERPDFSEILEALK 438 P RP F EI+ LK Sbjct: 1267 PKMRPTFLEIVNLLK 1281
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 52.0 bits (123), Expect = 2e-06 Identities = 27/76 (35%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ F + +WE+L+ GK P+ +L + +GV++KG R P+ L L+ +CW DP Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDP 666 Query: 479 AERPDFSEILEALKKI 432 ++RP F+E++ +L I Sbjct: 667 SDRPRFTELVCSLSDI 682
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 52.0 bits (123), Expect = 2e-06 Identities = 27/76 (35%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ F + +WE+L+ GK P+ +L + +GV++KG R P+ L L+ +CW DP Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDP 666 Query: 479 AERPDFSEILEALKKI 432 ++RP F+E++ +L I Sbjct: 667 SDRPRFTELVCSLSDI 682
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 52.0 bits (123), Expect = 2e-06 Identities = 29/89 (32%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL E++T G+IPY +T + + +++G R P N +L +L++ CW++ P Sbjct: 422 VWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYQLMRLCWKERP 480 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKHK 393 +RP F + L+ + E+ +G+++ Sbjct: 481 EDRPTF----DYLRSVLEDFFTATEGQYQ 505
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/75 (40%), Positives = 46/75 (61%), Gaps = 2/75 (2%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKG-LRPTIPKNAHAKLTELLQKCWQQD 483 ++SFG++LWE+ + + PY+ L+ Q V+ G L P P N +LT+L++ CWQ + Sbjct: 1220 MWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP--PDNCPERLTDLMRMCWQFN 1277 Query: 482 PAERPDFSEILEALK 438 P RP F EI+ LK Sbjct: 1278 PKMRPTFLEIVNLLK 1292
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/72 (41%), Positives = 45/72 (62%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P + L +L+ +CW++DP Sbjct: 443 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWRKDP 501 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 502 EERPTF-EYLQA 512
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/72 (41%), Positives = 45/72 (62%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P + L +L+ +CW++DP Sbjct: 443 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPDCPESLHDLMFQCWRKDP 501 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 502 EERPTF-EYLQA 512
>ANPRB_HUMAN (P20594) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 9/89 (10%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAA----VGVVQKGLRPTI-PKNAHAKLTE----LL 504 V+SFGI+L E+ P+ YL L + V V+ G RP P +L E L+ Sbjct: 707 VYSFGIILQEIALRSGPF-YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLM 765 Query: 503 QKCWQQDPAERPDFSEILEALKKIAEEVG 417 ++CW QDPAERPDF +I +++ +E G Sbjct: 766 ERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>ANPRB_BOVIN (P46197) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1047 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 9/89 (10%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAA----VGVVQKGLRPTI-PKNAHAKLTE----LL 504 V+SFGI+L E+ P+ YL L + V V+ G RP P +L E L+ Sbjct: 707 VYSFGIILQEIALRSGPF-YLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLM 765 Query: 503 QKCWQQDPAERPDFSEILEALKKIAEEVG 417 ++CW QDPAERPDF +I +++ +E G Sbjct: 766 ERCWAQDPAERPDFGQIKGFIRRFNKEGG 794
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDP 502 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 503 EERPTF-EYLQA 513
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 51.6 bits (122), Expect = 2e-06 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ + G PY + ++ G R P +A ++ +++ KCW +P Sbjct: 878 VWSFGILLWEIFSLGGTPYPGMIVDSTFYNKIKSGYRMAKPDHATHEVYDIMVKCWNSEP 937 Query: 479 AERPDF---SEILEAL 441 +RP F S+I+E+L Sbjct: 938 EKRPSFRHLSDIVESL 953
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + + ++Q G R P+ L E++ KCW Sbjct: 1264 VWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQ-GRRLLQPEYCPDALYEVMLKCWHPKA 1322 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1323 EMRPSFSELVSRISSIFSTFIGEH 1346
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 51.6 bits (122), Expect = 2e-06 Identities = 29/74 (39%), Positives = 43/74 (58%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGIL EL+T G++PY + + + V++G R P+ L EL+ CW++DP Sbjct: 452 VWSFGILQTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKKDP 510 Query: 479 AERPDFSEILEALK 438 ERP F I L+ Sbjct: 511 DERPTFEYIQSFLE 524
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDP 502 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 503 EERPTF-EYLQA 513
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1266 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1324 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1325 EMRPSFSELVSRISAIFSTFIGEH 1348
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1266 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1324 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1325 EMRPSFSELVSRISAIFSTFIGEH 1348
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDP 502 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 503 EERPTF-EYLQA 513
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1266 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1324 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1325 EMRPSFSELVSRISAIFSTFIGEH 1348
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1266 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1324 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1325 EMRPSFSELVSRISAIFSTFIGEH 1348
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1267 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1325 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1326 EMRPSFSELVSRISAIFSTFIGEH 1349
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1267 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1325 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1326 EMRPSFSELVSRISAIFSTFIGEH 1349
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 51.6 bits (122), Expect = 2e-06 Identities = 28/76 (36%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE+ + G++PY + PL+ V V+KG + P + ++++ C D Sbjct: 369 VWSFGILLWEIYSFGRVPYPRI-PLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCSHLDA 427 Query: 479 AERPDFSEILEALKKI 432 A RP F ++ E L+ I Sbjct: 428 ATRPTFLQLREQLEHI 443
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 51.6 bits (122), Expect = 2e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDP 502 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 503 EERPTF-EYLQA 513
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 51.6 bits (122), Expect = 2e-06 Identities = 29/74 (39%), Positives = 43/74 (58%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGIL EL+T G++PY + + + V++G R P+ L EL+ CW++DP Sbjct: 454 VWSFGILQTELVTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKKDP 512 Query: 479 AERPDFSEILEALK 438 ERP F I L+ Sbjct: 513 DERPTFEYIQSFLE 526
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 51.2 bits (121), Expect = 3e-06 Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 1/71 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGI L+E+ T G++PY + P + + G R P++ H +L +L++ CW + P Sbjct: 383 VWSFGICLYEIFTLGQLPYPDV-PSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKP 441 Query: 479 AERPDFSEILE 447 RP+FS +E Sbjct: 442 ELRPNFSNCVE 452
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GILLWE+ + G PY + +V+ G + P A + ++Q CW +P Sbjct: 870 VWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEP 929 Query: 479 AERPDFSEILEALKKIAEE 423 RP F +I L+K A+E Sbjct: 930 TRRPTFQQICSLLQKQAQE 948
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 51.2 bits (121), Expect = 3e-06 Identities = 26/76 (34%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L +L+ CWQ+D Sbjct: 807 VWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDR 865 Query: 479 AERPDFSEILEALKKI 432 RP F+EI+ L K+ Sbjct: 866 NSRPRFAEIVNTLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 51.2 bits (121), Expect = 3e-06 Identities = 26/76 (34%), Positives = 47/76 (61%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L +L+ CWQ+D Sbjct: 807 VWSYGIVMWEVMSFGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDR 865 Query: 479 AERPDFSEILEALKKI 432 RP F+EI+ L K+ Sbjct: 866 NSRPRFAEIVNTLDKM 881
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 51.2 bits (121), Expect = 3e-06 Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE++T G PY ++ + + G R P + ++++CW + Sbjct: 924 VWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFES 983 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKHKDKS 384 RP F+E++E+ I ++ + + D S Sbjct: 984 CARPTFAELVESFDGILQQASSNPNDAYLDLS 1015
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/76 (38%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILLWE + G PY L+ Q V+KG R P+ + L+++CW +P Sbjct: 398 VWSFGILLWETFSLGASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEP 456 Query: 479 AERPDFSEILEALKKI 432 +RP FS + L+ I Sbjct: 457 GQRPSFSAFYQELQSI 472
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GILLWE+ + G PY + +V+ G + P A + ++Q CW +P Sbjct: 836 VWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEP 895 Query: 479 AERPDFSEILEALKKIAEE 423 RP F +I L+K A+E Sbjct: 896 TRRPTFQQICSLLQKQAQE 914
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 51.2 bits (121), Expect = 3e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1266 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1324 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1325 ELRPSFSELVSRISAIFSTFIGEH 1348
>PGFRA_MOUSE (P26618) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1089 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GILLWE+ + G PY + ++ G R P +A +++ E++ +CW +P Sbjct: 878 VWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEP 937 Query: 479 AERPDF---SEILEAL 441 +RP F SEI+E L Sbjct: 938 EKRPSFYHLSEIVENL 953
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FG+L WE+ T G+ PY + + V++G R P+ KL LL +CW+ +P Sbjct: 2421 VWAFGVLCWEIFTLGQQPYAARNNFEV-LAHVKEGGRLQQPERCPEKLYALLLQCWRSEP 2479 Query: 479 AERPDFSEILEALKKIAEEV 420 ERP F L L+ ++ ++ Sbjct: 2480 WERPSFKRCLSTLQALSSDL 2499
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 51.2 bits (121), Expect = 3e-06 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G PY + + +++G R P ++ + + CW +P Sbjct: 1088 VWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEP 1147 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGK 399 ++RP FSE++E L + + + DGK Sbjct: 1148 SQRPTFSELVEHLGNLL-QANAQQDGK 1173
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G PY + + ++ G R P+ A + ++ CW DP Sbjct: 1097 VWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDP 1156 Query: 479 AERPDFSEILEALKKIAEEVG 417 RP FSE++E L + + G Sbjct: 1157 KARPAFSELVEILGDLLQGRG 1177
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GILLWE+ + G PY + +V+ G + P A + ++Q CW +P Sbjct: 838 VWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEP 897 Query: 479 AERPDFSEILEALKKIAEEVGDEHD 405 RP F +I L++ A+E E D Sbjct: 898 THRPTFQQICSFLQEQAQEDRRERD 922
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 50.8 bits (120), Expect = 3e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMGNGEV-LDRVERGYRMPCPPECPESLHDLMSQCWRRDP 502 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 503 EERPTF-EYLQA 513
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/66 (40%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKDP 502 Query: 479 AERPDF 462 ERP F Sbjct: 503 EERPTF 508
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+++ G PY +T + + Q R P+N ++ EL+++CW+ P Sbjct: 1034 VWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-AYRMEQPRNCDDEVYELMRQCWRDRP 1092 Query: 479 AERPDFSEILEALKKIAE 426 ERP F++I L ++ E Sbjct: 1093 YERPPFAQIALQLGRMLE 1110
>PGFRA_RAT (P20786) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1088 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+LLWE+ + G PY + ++ G R P +A +++ E++ +CW +P Sbjct: 877 VWSYGVLLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEP 936 Query: 479 AERPDF---SEILEAL 441 +RP F SEI+E L Sbjct: 937 EKRPSFYHLSEIVENL 952
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1266 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPRA 1324 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1325 ELRPSFSELVSRISAIFSTFIGEH 1348
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ + G PY + + +++G R P ++ + + CW DP Sbjct: 1081 VWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGDP 1140 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGK 399 +RP FSE++E L + + DGK Sbjct: 1141 KQRPTFSELVEHLGNLL-QANVRQDGK 1166
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++ R P + A L +L+ CWQ+D Sbjct: 725 VWSYGIVMWEVMSYGERPYWDMSN-QDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDR 783 Query: 479 AERPDFSEILEALKKI 432 RP F EI+ L K+ Sbjct: 784 NSRPRFGEIVNTLDKM 799
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 50.8 bits (120), Expect = 3e-06 Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGIL EL T G++PY + + + V++G R P+ L EL+ CW++DP Sbjct: 450 VWSFGILQTELTTKGRVPYPGMVNREV-LEQVERGYRMPCPQGCPESLHELMNLCWKKDP 508 Query: 479 AERPDFSEILEALK 438 ERP F I L+ Sbjct: 509 DERPTFEYIQSFLE 522
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWE+ T G P + P++ ++++G R P N +L +++ CW P Sbjct: 683 VWSFGVLLWEIFTLGGSPNPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVP 741 Query: 479 AERPDFSEILEALKKI 432 ++RP F +++E L +I Sbjct: 742 SQRPTFKQLVEDLDRI 757
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 50.8 bits (120), Expect = 3e-06 Identities = 27/74 (36%), Positives = 45/74 (60%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE++T + PY+ L+ Q V+ G+ + +N +L EL++ CWQ P Sbjct: 1175 VWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL-ENCPIQLQELMRLCWQHSP 1233 Query: 479 AERPDFSEILEALK 438 RP F IL+ ++ Sbjct: 1234 RLRPTFVHILDRIQ 1247
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 50.8 bits (120), Expect = 3e-06 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+ F + +WE+L+ GK P+ +L + +GV++KG R P L L+ +CW DP Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLEN-KDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDP 666 Query: 479 AERPDFSEILEALKKI 432 ++RP F+E++ +L + Sbjct: 667 SDRPRFTELVCSLSDV 682
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LLWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1267 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPRA 1325 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1326 ELRPSFSELVSRISAIFSTFIGEH 1349
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 50.8 bits (120), Expect = 3e-06 Identities = 25/81 (30%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++L+E++T G+ PY +T + + +Q+ R P N + +++ CW++DP Sbjct: 418 VWSFGVVLYEIITYGRFPYPGMTNPEV-LEKIQQNYRMPCPANCPKQFHDIMLDCWREDP 476 Query: 479 AERPDFSEILEALKKIAEEVG 417 A RP F + L++ G Sbjct: 477 ASRPTFETLQWQLEEFFNSEG 497
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/89 (31%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGIL+ E++T G+IPY +T + + +++G R P N +L +L+ +CW++ P Sbjct: 422 VWSFGILMTEIVTHGRIPYPGMTNPEV-IQNLERGYRMPRPDNCPEELYKLMMQCWRERP 480 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKHK 393 +RP F + L+ + E+ +G+++ Sbjct: 481 DDRPTF----DYLRSVLEDFFTATEGQYQ 505
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 50.8 bits (120), Expect = 3e-06 Identities = 29/89 (32%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL E++T G+IPY +T + + +++G R P N +L L+ CW++ P Sbjct: 422 VWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYHLMMLCWKERP 480 Query: 479 AERPDFSEILEALKKIAEEVGDEHDGKHK 393 +RP F + L+ + E+ +G+++ Sbjct: 481 EDRPTF----DYLRSVLEDFFTATEGQYQ 505
>BMX_HUMAN (P51813) Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)| (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38) Length = 675 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/84 (33%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V++FGIL+WE+ + GK PY+ Q + V Q G R P A + +++ CW + P Sbjct: 595 VWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQ-GHRLYRPHLASDTIYQIMYSCWHELP 653 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 +RP F ++L +++ + E+ D+H Sbjct: 654 EKRPTFQQLLSSIEPLREK--DKH 675
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 50.4 bits (119), Expect = 5e-06 Identities = 25/76 (32%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY +T Q + +++ R P + + L +L+ CWQ+D Sbjct: 817 VWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDR 875 Query: 479 AERPDFSEILEALKKI 432 RP F +I+ L K+ Sbjct: 876 NHRPKFGQIVNTLDKM 891
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 50.4 bits (119), Expect = 5e-06 Identities = 24/76 (31%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ++ Sbjct: 807 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKER 865 Query: 479 AERPDFSEILEALKKI 432 ++RP F +I+ L K+ Sbjct: 866 SDRPKFGQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 50.4 bits (119), Expect = 5e-06 Identities = 24/76 (31%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ++ Sbjct: 807 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKER 865 Query: 479 AERPDFSEILEALKKI 432 ++RP F +I+ L K+ Sbjct: 866 SDRPKFGQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 50.4 bits (119), Expect = 5e-06 Identities = 24/76 (31%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ++ Sbjct: 807 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKER 865 Query: 479 AERPDFSEILEALKKI 432 ++RP F +I+ L K+ Sbjct: 866 SDRPKFGQIVNMLDKL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 50.4 bits (119), Expect = 5e-06 Identities = 24/76 (31%), Positives = 48/76 (63%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY ++ Q + +++G R P + L +L+ CWQ++ Sbjct: 806 VWSYGIVMWEVMSYGERPYWDMSN-QDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKER 864 Query: 479 AERPDFSEILEALKKI 432 ++RP F +I+ L K+ Sbjct: 865 SDRPKFGQIVSMLDKL 880
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 50.4 bits (119), Expect = 5e-06 Identities = 25/76 (32%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY +T Q + +++ R P + + L +L+ CWQ+D Sbjct: 809 VWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDR 867 Query: 479 AERPDFSEILEALKKI 432 RP F +I+ L K+ Sbjct: 868 NHRPKFGQIVNTLDKM 883
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 441 VWSFGILLTELTTKGRVPYPGMVNGEV-LDRVERGYRMPCPPECPESLHDLMCQCWRKDP 499 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 500 EERPTF-EYLQA 510
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWEL+T G PY + V ++Q G R P+ L E++ KCW Sbjct: 1266 VWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQ-GRRLLQPEYCPDPLYEVMLKCWHPKA 1324 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP FSE++ + I EH Sbjct: 1325 EMRPSFSELVSRISAIFSTFIGEH 1348
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 50.4 bits (119), Expect = 5e-06 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+ +WEL+T G PY+ + P + V++ G R P ++ ++ KCW DP Sbjct: 895 VWSYGVTVWELMTFGSKPYDGI-PAKEIASVLENGERLPQPPICTIEVYMIILKCWMIDP 953 Query: 479 AERPDFSEILEALKKIAEE 423 + RP F E++ ++A + Sbjct: 954 SSRPRFRELVGEFSQMARD 972
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 50.4 bits (119), Expect = 5e-06 Identities = 27/74 (36%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 ++SFG++LWE+ + + PY+ L+ Q V+ G P N ++T+L++ CWQ +P Sbjct: 1219 MWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQ-PDNCPERVTDLMRMCWQFNP 1277 Query: 479 AERPDFSEILEALK 438 RP F EI+ LK Sbjct: 1278 KMRPTFLEIVNLLK 1291
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 50.4 bits (119), Expect = 5e-06 Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL+E++T GK+PY +T Q + ++ + R P N + ++ +CW +P Sbjct: 416 VWSFGILLYEIITYGKMPYSGMTGAQV-IQMLAQNYRLPQPSNCPQQFYNIMLECWNAEP 474 Query: 479 AERPDFSEI 453 ERP F + Sbjct: 475 KERPTFETL 483
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 50.4 bits (119), Expect = 5e-06 Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -3 Query: 653 FSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDPA 477 +SFG+LLWE+ + G +PY T Q + V G R P+ + ++ +CWQ +P Sbjct: 707 WSFGVLLWEIFSLGYMPYPGRTN-QEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPE 765 Query: 476 ERPDFSEILEALKKIAEE 423 RP F+ ILE L+ ++ Sbjct: 766 LRPSFASILERLQYCTQD 783
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 50.4 bits (119), Expect = 5e-06 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 3/76 (3%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIP---KNAHAKLTELLQKCWQQ 486 V+SFGI+LW + K PYE + + V ++ G RP + + ++ L+++CWQ Sbjct: 212 VYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQA 271 Query: 485 DPAERPDFSEILEALK 438 P +RP F I E + Sbjct: 272 IPEDRPTFLGIEEEFR 287
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 50.1 bits (118), Expect = 6e-06 Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 7/79 (8%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPY------EYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQK 498 V++ G+L+WE+ T G++P+ E L LQA + + P+ +KL L+Q+ Sbjct: 989 VWASGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQ------PEGCPSKLYRLMQR 1042 Query: 497 CWQQDPAERPDFSEILEAL 441 CW P +RP FSEI AL Sbjct: 1043 CWALSPKDRPSFSEIASAL 1061
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 50.1 bits (118), Expect = 6e-06 Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+++P Sbjct: 452 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKEP 510 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 511 EERPTF-EYLQA 521
>ERBB_AVIEU (P11273) Tyrosine-protein kinase transforming protein erbB (EC| 2.7.10.1) Length = 540 Score = 50.1 bits (118), Expect = 6e-06 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+ +WEL+T G PY+ + P V++KG R P + ++ KCW D Sbjct: 317 VWSYGVTVWELMTFGSKPYDGI-PASEISSVLEKGERLPQPPICTIDVYMIMVKCWMSDA 375 Query: 479 AERPDFSEILEALKKIAEE 423 RP F E++ K+A + Sbjct: 376 DSRPKFRELIAEFSKMARD 394
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 50.1 bits (118), Expect = 6e-06 Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+++P Sbjct: 447 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKEP 505 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 506 EERPTF-EYLQA 516
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 50.1 bits (118), Expect = 6e-06 Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW+++P Sbjct: 447 VWSFGILLTELTTKGRVPYPGMVNREV-LDQVERGYRMPCPPECPESLHDLMCQCWRKEP 505 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 506 EERPTF-EYLQA 516
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 50.1 bits (118), Expect = 6e-06 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GIL+WE+ + G PY +T +A + G R PK+ ++ L+ +CW D Sbjct: 1243 VWSYGILMWEIFSKGDTPYSGMTNSRARERI-DTGYRMPTPKSTPEEMYRLMLQCWAADA 1301 Query: 479 AERPDFSEILEALKKIAEEVGDEH 408 RP F EI + + + + H Sbjct: 1302 ESRPHFDEIYNVVDALILRLDNSH 1325
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 50.1 bits (118), Expect = 6e-06 Identities = 27/73 (36%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL E++T G+IPY +T + + +++G R P N +L L+ CW++ P Sbjct: 422 VWSFGILLTEIVTHGRIPYPGMTNPEV-IQNLERGYRMVRPDNCPEELYHLMMLCWKERP 480 Query: 479 AERPDFSEILEAL 441 +RP F + L Sbjct: 481 EDRPTFDYLRSVL 493
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 49.7 bits (117), Expect = 8e-06 Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+L+ E++T G++PY +T Q + V +G R P+ L +++ CW+ +P Sbjct: 245 VWSFGVLISEIVTHGRMPYPGMTNRQV-LEAVDRGYRMPCPEGCPDPLYKIMLSCWKHEP 303 Query: 479 AERPDFSEILEALKKIAEE 423 +RP F E+LK + E+ Sbjct: 304 DDRPTF----ESLKNLLED 318
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/76 (38%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL+E+ T G+ PYE +T + + + +G R P A++ L+ +CW+ P Sbjct: 413 VWSFGILLYEVFTYGQCPYEGMTNHET-LQQISRGYRLPRPAVCPAEVYVLMVECWKGSP 471 Query: 479 AERPDFSEILEALKKI 432 ERP F+ + E L I Sbjct: 472 EERPTFAILREKLNAI 487
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 49.7 bits (117), Expect = 8e-06 Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+G+++WE++T PY+ L+ + V + G +P+N ++ L+Q CW + P Sbjct: 1233 VWSYGVVMWEMVTLAAQPYQGLSN-EEVVKFISDGYIMELPENCPNEMAYLMQHCWAKKP 1291 Query: 479 AERPDFSEILEAL 441 +RP F I+E L Sbjct: 1292 NQRPTFKAIIEYL 1304
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 49.7 bits (117), Expect = 8e-06 Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG+LL E+ T G+ PYE +T + + + +G R P A++ L+ +CW+ P Sbjct: 409 VWSFGVLLHEVFTYGQCPYEGMTNHET-LQQIMRGYRLPRPAACPAEVYVLMLECWRSSP 467 Query: 479 AERPDFSEILEALKKI 432 ERP F+ + E L I Sbjct: 468 EERPSFATLREKLHAI 483
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 49.7 bits (117), Expect = 8e-06 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 6/71 (8%) Frame = -3 Query: 656 VFSFGILLWELLTGKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAK------LTELLQKC 495 V+SF I++W +LT K P+ + + V KG RP +P A+ L L+Q+C Sbjct: 206 VYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRC 265 Query: 494 WQQDPAERPDF 462 WQ DP RP F Sbjct: 266 WQGDPRVRPTF 276
>EPHA1_HUMAN (P21709) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH) Length = 976 Score = 49.7 bits (117), Expect = 8e-06 Identities = 27/76 (35%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGI++WE+L+ G PY ++ Q + ++ G R P + A L EL++ CW D Sbjct: 809 VWSFGIVMWEVLSFGDKPYGEMSN-QEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDR 867 Query: 479 AERPDFSEILEALKKI 432 A RP F ++ L+++ Sbjct: 868 ARRPHFQKLQAHLEQL 883
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 49.7 bits (117), Expect = 8e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMGNGEV-LDRVERGYRMPCPPECPESLHDLMCQCWRRDP 502 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 503 EERPTF-EYLQA 513
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 49.7 bits (117), Expect = 8e-06 Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFGILL EL T G++PY + + + V++G R P L +L+ +CW++DP Sbjct: 444 VWSFGILLTELTTKGRVPYPGMGNGEV-LDRVERGYRMPCPPECPESLHDLMCQCWRRDP 502 Query: 479 AERPDFSEILEA 444 ERP F E L+A Sbjct: 503 EERPTF-EYLQA 513
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 49.7 bits (117), Expect = 8e-06 Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 1/83 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+SFG++LWE+ T PY+ T Q V+ G P+ +L E + CW +DP Sbjct: 1235 VWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNG-HLDYPEGCDYQLREFMSLCWHRDP 1293 Query: 479 AERPDFSEILEALKKIAEEVGDE 411 RP F EI+ L+ EV D+ Sbjct: 1294 KMRPSFLEIVHVLE---NEVDDD 1313
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 49.3 bits (116), Expect = 1e-05 Identities = 25/76 (32%), Positives = 45/76 (59%), Gaps = 1/76 (1%) Frame = -3 Query: 656 VFSFGILLWELLT-GKIPYEYLTPLQAAVGVVQKGLRPTIPKNAHAKLTELLQKCWQQDP 480 V+S+GI++WE+++ G+ PY +T Q + +++ R P + L +L+ CWQ+D Sbjct: 827 VWSYGIVMWEVMSYGERPYWDMTN-QDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDR 885 Query: 479 AERPDFSEILEALKKI 432 RP F +I+ L K+ Sbjct: 886 NHRPKFGQIVNTLDKM 901 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,160,949 Number of Sequences: 219361 Number of extensions: 1820775 Number of successful extensions: 6118 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5520 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5717 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6257125380 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
