ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal24p12 |
|---|---|
| Clone Library Name | barley_pub |
>AKR2_ARATH (Q9SAR5) Ankyrin repeat domain-containing protein 2 (AtAKR2)| Length = 342 Score = 224 bits (570), Expect = 2e-58 Identities = 115/168 (68%), Positives = 133/168 (79%) Frame = -3 Query: 675 KYWNDPEILQKIGEAMSLNFPVDAATSTVLSGPQXXXXXXXXXXESIVHNTASVGDAEGL 496 KYWNDPE+L+K+GEAM + PV +S + ESIVH TAS+GD EGL Sbjct: 178 KYWNDPEVLKKLGEAMGM--PVAGLPDQTVSA-EPEVAEEGEEEESIVHQTASLGDVEGL 234 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 K AL G NKDEED EGR ALHFACGYGELKCA++L++AGA+V+A+DKNKNTPLHYAAGY Sbjct: 235 KAALASGGNKDEEDSEGRTALHFACGYGELKCAQVLIDAGASVNAVDKNKNTPLHYAAGY 294 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL 172 GRKECV LLL++GAAV LQNLD KTPI+VAKLNSQ EVVKLLE+D FL Sbjct: 295 GRKECVSLLLENGAAVTLQNLDEKTPIDVAKLNSQLEVVKLLEKDAFL 342
>TNKS1_HUMAN (O95271) Tankyrase 1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1)| (TRF1-interacting ankyrin-related ADP-ribose polymerase) Length = 1327 Score = 76.6 bits (187), Expect = 6e-14 Identities = 47/121 (38%), Positives = 64/121 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A ++ L GA+ +D G LH AC YG + AE+L+ GA+V+ D Sbjct: 688 LHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVAD 747 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 K TPLH AA G+ E LLLKHGA +N DG TP+++ K D + LL+ D Sbjct: 748 LWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTD-IQDLLKGDAA 806 Query: 174 L 172 L Sbjct: 807 L 807 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/115 (35%), Positives = 64/115 (55%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A + E + L+ GA+ + +D G LH A YG + A +L++ V+A D Sbjct: 841 LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 900 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K TPLH AA GR + LLL HGA ++N +G+TP+++A + D++ LL Sbjct: 901 KWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA---TADDIRALL 952 Score = 68.9 bits (167), Expect = 1e-11 Identities = 40/103 (38%), Positives = 55/103 (53%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A ++ L GA+ +D G LH AC YG + E+LL+ GA V+A+D Sbjct: 373 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 432 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 + TPLH AA R E LLL HGA L N GK+ +++A Sbjct: 433 LWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475 Score = 68.6 bits (166), Expect = 2e-11 Identities = 42/106 (39%), Positives = 58/106 (54%), Gaps = 2/106 (1%) Frame = -3 Query: 450 EGRRA--LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 +GR++ LH A GY ++ ++LL+ GA V A DK PLH A YG E +LLLKHG Sbjct: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 425 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID 139 A V +L TP+ A ++ EV LL S +DP L++ Sbjct: 426 ACVNAMDLWQFTPLHEAASKNRVEVCSLLL------SHGADPTLVN 465 Score = 63.2 bits (152), Expect = 7e-10 Identities = 38/105 (36%), Positives = 56/105 (53%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G + ++ L GAN D G LH AC +G + +LL GA +A Sbjct: 218 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNA 277 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 D TPLH AA G+ + +LL+HGA ++N DGK+ +++A Sbjct: 278 RDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/112 (36%), Positives = 59/112 (52%), Gaps = 2/112 (1%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRA--LHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 GD +K+ +D AN + +D+ GR++ LHFA G+G E LL+ GA V A D Sbjct: 193 GDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLI 251 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 PLH A +G E V LLL GA ++ TP+ A + + +V +L Q Sbjct: 252 PLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 303 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/102 (37%), Positives = 45/102 (44%) Frame = -3 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 K L G KDE L A E K +L A D K+TPLH AAGY Sbjct: 327 KAVLTGEYKKDE-------LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGY 379 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 R V LLL+HGA V ++ G P+ A EV +LL Sbjct: 380 NRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELL 421 Score = 44.7 bits (104), Expect = 3e-04 Identities = 37/137 (27%), Positives = 55/137 (40%), Gaps = 22/137 (16%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G E K L GA+ +++ +G L G+ ++L A +DA Sbjct: 754 LHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDIQDLLKGDAALLDAAK 812 Query: 354 KN----------------------KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKT 241 K +TPLH AAGY E + LL+HGA V Q+ G Sbjct: 813 KGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLI 872 Query: 240 PIEVAKLNSQDEVVKLL 190 P+ A ++ LL Sbjct: 873 PLHNAASYGHVDIAALL 889 Score = 44.7 bits (104), Expect = 3e-04 Identities = 24/57 (42%), Positives = 32/57 (56%) Frame = -3 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L+ +TPLH+AAGY R V+ LL HGA V ++ G P+ A EV +LL Sbjct: 680 LEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELL 736 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/85 (34%), Positives = 44/85 (51%) Frame = -3 Query: 396 EILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLN 217 E+LL GA V+ +K+ TPLH AA + +++L KHGA + + G+T + A L Sbjct: 542 ELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALA 601 Query: 216 SQDEVVKLLEQDVFL*SKPSDPVLI 142 + +LL S SDP +I Sbjct: 602 GHLQTCRLLL------SYGSDPSII 620 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/83 (32%), Positives = 42/83 (50%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GAN +E++ + LH A E+L + GA ++ALD T LH AA G + Sbjct: 548 GANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTC 607 Query: 297 DLLLKHGAAVMLQNLDGKTPIEV 229 LLL +G+ + +L G T ++ Sbjct: 608 RLLLSYGSDPSIISLQGFTAAQM 630 Score = 33.5 bits (75), Expect = 0.61 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Frame = -3 Query: 354 KNKNTPLHYAAGY---GRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 ++ T LH A RK+ +LLL+ GA V +N D TP+ VA + ++V+++L + Sbjct: 520 QSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHK 579
>ANR11_HUMAN (Q6UB99) Ankyrin repeat domain-containing protein 11 (Ankyrin| repeat-containing cofactor 1) Length = 2664 Score = 75.5 bits (184), Expect = 1e-13 Identities = 50/139 (35%), Positives = 72/139 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A GDA +K+ + GA+ + +D G ALH AC G A+ LL AGA V+ Sbjct: 173 LHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKG 232 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 + +TPLH AA G + V LLL++G N G+TP++VA NS V LL + + Sbjct: 233 LDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA--NSPTMVNLLLGKGTY 290 Query: 174 L*SKPSDPVLIDPKTLPCF 118 S+ S + + P F Sbjct: 291 TSSEESSTESSEEEDAPSF 309 Score = 44.7 bits (104), Expect = 3e-04 Identities = 35/107 (32%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Frame = -3 Query: 495 KKALDGGANKDEEDVE-----GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 +K A+K ++ V G LH A G+ + + L+ GA V+ D T LH Sbjct: 148 QKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALH 207 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A G + LL GA V + LD TP+ A N +VVKLL Sbjct: 208 EACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLL 254
>ANR12_HUMAN (Q6UB98) Ankyrin repeat domain-containing protein 12 (Ankyrin| repeat-containing cofactor 2) (GAC-1 protein) Length = 2062 Score = 75.1 bits (183), Expect = 2e-13 Identities = 43/119 (36%), Positives = 68/119 (57%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A GD + +K+ + GAN + +D G LH AC G A+IL+ AGA V+ Sbjct: 189 LHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQG 248 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDV 178 + +TPLH +A G ++ V LLL+HG N G+ P++VA+ +E+ LL+++V Sbjct: 249 LDDDTPLHDSASSGHRDIVKLLLRHGGNAFQANKHGERPVDVAE---TEELELLLKREV 304 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/92 (32%), Positives = 46/92 (50%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 ++ + G LH A G++K + L+ GA V+ D TPLH A G + +L+ Sbjct: 179 NKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILI 238 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 GA V Q LD TP+ + + ++VKLL Sbjct: 239 AAGADVNTQGLDDDTPLHDSASSGHRDIVKLL 270
>ASB8_MOUSE (Q91ZT9) Ankyrin repeat and SOCS box protein 8 (ASB-8)| Length = 288 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/115 (39%), Positives = 64/115 (55%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H V DA+ ++ L+ GA + D R ALH+A E C E+LLE GA +ALD Sbjct: 57 LHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERDEA-CVEVLLEYGANPNALD 115 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 N++TPLH+AA ECV LL+ GA+V + + TP+ A + E V +L Sbjct: 116 GNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSIL 170 Score = 68.9 bits (167), Expect = 1e-11 Identities = 40/96 (41%), Positives = 56/96 (58%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ D ++ L+ GAN + D LH+A +C LLE+GA+V+ALD N + Sbjct: 93 AAERDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNND 152 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 TPL +AA G E V +LL +GA V + NL G+TPI Sbjct: 153 TPLSWAAMKGNLESVSILLDYGAEVRVINLKGQTPI 188 Score = 56.6 bits (135), Expect = 7e-08 Identities = 33/84 (39%), Positives = 47/84 (55%) Frame = -3 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVML 262 + LH AC + C E+LLE GA V+ALD T LHYAA + CV++LL++GA Sbjct: 55 KPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERD-EACVEVLLEYGANPNA 113 Query: 261 QNLDGKTPIEVAKLNSQDEVVKLL 190 + + TP+ A + E V+ L Sbjct: 114 LDGNRDTPLHWAAFKNNAECVRAL 137 Score = 33.9 bits (76), Expect = 0.47 Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 8/112 (7%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A +AE ++ L+ GA+ + D L +A G L+ ILL+ GA V ++ Sbjct: 122 LHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVIN 181 Query: 354 KNKNTPLH-----YAAGYGRKE---CVDLLLKHGAAVMLQNLDGKTPIEVAK 223 TP+ G G ++ C +LL + L+ +G P EV K Sbjct: 182 LKGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGQFELRK-NGIMPREVTK 232
>ASB8_HUMAN (Q9H765) Ankyrin repeat and SOCS box protein 8 (ASB-8)| Length = 288 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/115 (39%), Positives = 64/115 (55%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H V DA+ ++ L+ GA + D R ALH+A E C E+LLE GA +ALD Sbjct: 57 LHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEA-CVEVLLEYGANPNALD 115 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 N++TPLH+AA ECV LL+ GA+V + + TP+ A + E V +L Sbjct: 116 GNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSIL 170 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/96 (41%), Positives = 56/96 (58%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ D ++ L+ GAN + D LH+A +C LLE+GA+V+ALD N + Sbjct: 93 AAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNND 152 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 TPL +AA G E V +LL +GA V + NL G+TPI Sbjct: 153 TPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPI 188 Score = 56.6 bits (135), Expect = 7e-08 Identities = 33/84 (39%), Positives = 47/84 (55%) Frame = -3 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVML 262 + LH AC + C E+LLE GA V+ALD T LHYAA + CV++LL++GA Sbjct: 55 KPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKD-EACVEVLLEYGANPNA 113 Query: 261 QNLDGKTPIEVAKLNSQDEVVKLL 190 + + TP+ A + E V+ L Sbjct: 114 LDGNRDTPLHWAAFKNNAECVRAL 137 Score = 33.5 bits (75), Expect = 0.61 Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 8/112 (7%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A +AE ++ L+ GA+ + D L +A G L+ ILL+ GA V ++ Sbjct: 122 LHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVIN 181 Query: 354 KNKNTPLH-----YAAGYGRKE---CVDLLLKHGAAVMLQNLDGKTPIEVAK 223 TP+ G G ++ C +LL + L+ +G P EVA+ Sbjct: 182 LIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRK-NGTMPREVAR 232
>TNKS2_HUMAN (Q9H2K2) Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2)| (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein) Length = 1166 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/121 (37%), Positives = 64/121 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A ++ L GA+ +D G LH AC YG + AE+L++ GA V+ D Sbjct: 530 LHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD 589 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 K TPLH AA G+ E LLL+HGA +N DG TP+++ K + ++ LL D Sbjct: 590 LWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVK-DGDTDIQDLLRGDAA 648 Query: 174 L 172 L Sbjct: 649 L 649 Score = 70.9 bits (172), Expect = 3e-12 Identities = 45/115 (39%), Positives = 63/115 (54%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A + E + L GA+ + +D G LH A YG + A +L++ A V+A D Sbjct: 683 LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATD 742 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K TPLH AA GR + LLL HGA L+N +G+TP++ L S D+V LL Sbjct: 743 KWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLD---LVSADDVSALL 794 Score = 68.6 bits (166), Expect = 2e-11 Identities = 52/159 (32%), Positives = 76/159 (47%), Gaps = 2/159 (1%) Frame = -3 Query: 609 DAATSTVLSGPQXXXXXXXXXXESIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRA-- 436 D T+ L+ P + + +A G+ E + AL N + +GR++ Sbjct: 156 DGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMM-ALLTPLNVNCHASDGRKSTP 214 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A GY +K ++LL+ GA V A DK PLH A YG E +LL+KHGA V + Sbjct: 215 LHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMD 274 Query: 255 LDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID 139 L TP+ A ++ EV LL S +DP L++ Sbjct: 275 LWQFTPLHEAASKNRVEVCSLLL------SYGADPTLLN 307 Score = 66.6 bits (161), Expect = 6e-11 Identities = 41/126 (32%), Positives = 65/126 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + ++ L GAN D G LH AC +G + +LL GA +A D Sbjct: 62 LHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARD 121 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 TPLH AA G+ + +LL+HGA ++N DG+T +++A +++ + ++D Sbjct: 122 NWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDEL 181 Query: 174 L*SKPS 157 L S S Sbjct: 182 LESARS 187 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/103 (35%), Positives = 54/103 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A + ++ L GA+ +D LH AC YG + E+L++ GA V+A+D Sbjct: 215 LHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMD 274 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 + TPLH AA R E LLL +GA L N K+ I++A Sbjct: 275 LWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLA 317 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/86 (38%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Frame = -3 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALDK--NKNTPLHYAAGYGRKECVDLLLKHGAAV 268 R L AC G+++ + L+ V++ D K+TPLH+AAG+GRK+ V+ LL++GA V Sbjct: 26 RELFEACRNGDVERVKRLVTP-EKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANV 84 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ G P+ A EVV LL Sbjct: 85 QARDDGGLIPLHNACSFGHAEVVNLL 110 Score = 47.4 bits (111), Expect = 4e-05 Identities = 33/110 (30%), Positives = 52/110 (47%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 S+G++E ++ L+ D E V+ C + C +I + ++T Sbjct: 486 SLGNSEADRQLLEAAKAGDVETVKK------LCTVQSVNCRDI-----------EGRQST 528 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 PLH+AAGY R V+ LL+HGA V ++ G P+ A EV +LL Sbjct: 529 PLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELL 578 Score = 46.2 bits (108), Expect = 9e-05 Identities = 34/113 (30%), Positives = 56/113 (49%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GAN +E+ E LH A E++++ A V+ALD T LH AA G + Sbjct: 390 GANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTC 449 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID 139 LLL +G + +L G T +++ N Q +LL++ + L + +D L++ Sbjct: 450 RLLLSYGCDPNIISLQGFTALQMGNENVQ----QLLQEGISLGNSEADRQLLE 498 Score = 45.1 bits (105), Expect = 2e-04 Identities = 38/137 (27%), Positives = 55/137 (40%), Gaps = 22/137 (16%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G E K L GA+ +++ +G L G+ ++L A +DA Sbjct: 596 LHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKD-GDTDIQDLLRGDAALLDAAK 654 Query: 354 KN----------------------KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKT 241 K +TPLH AAGY E + LL+HGA V Q+ G Sbjct: 655 KGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLI 714 Query: 240 PIEVAKLNSQDEVVKLL 190 P+ A +V LL Sbjct: 715 PLHNAASYGHVDVAALL 731 Score = 35.0 bits (79), Expect = 0.21 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 3/86 (3%) Frame = -3 Query: 438 ALHFACG--YGELK-CAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 ALH A Y + K E+LL GA ++ K TPLH A+ + V++++KH A V Sbjct: 367 ALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKV 426 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 + G+T + A + +LL Sbjct: 427 NALDNLGQTSLHRAAYCGHLQTCRLL 452
>ANK3_HUMAN (Q12955) Ankyrin-3 (ANK-3) (Ankyrin-G)| Length = 4377 Score = 75.1 bits (183), Expect = 2e-13 Identities = 48/147 (32%), Positives = 72/147 (48%) Frame = -3 Query: 621 NFPVDAATSTVLSGPQXXXXXXXXXXESIVHNTASVGDAEGLKKALDGGANKDEEDVEGR 442 N PVD T+ L+ +H A G + K LD AN + + + G Sbjct: 357 NVPVDDVTNDYLTA---------------LHVAAHCGHYKVAKVLLDKKANPNAKALNGF 401 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVML 262 LH AC +K E+LL+ GA++ A+ ++ TP+H AA G V L+ HGA+ Sbjct: 402 TPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNT 461 Query: 261 QNLDGKTPIEVAKLNSQDEVVKLLEQD 181 N+ G+T + +A + Q EVV+ L QD Sbjct: 462 TNVRGETALHMAARSGQAEVVRYLVQD 488 Score = 69.3 bits (168), Expect = 1e-11 Identities = 40/115 (34%), Positives = 54/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A D + L N D E G LH A YG + A +LL AAVD Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTA 265 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N TPLH A+ G V LLL GA + + DG TP+ + ++VV++L Sbjct: 266 RNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML 320 Score = 67.4 bits (163), Expect = 4e-11 Identities = 42/115 (36%), Positives = 59/115 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G E + + L AN D +G ALH A G+ + ++L+ GA V+A Sbjct: 78 LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQS 137 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N TPL+ AA E V LL +GA+ L DG TP+ VA D+VV LL Sbjct: 138 QNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 192 Score = 65.1 bits (157), Expect = 2e-10 Identities = 43/117 (36%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H +A G + LD GA+ +G LH A YG+L+ A +LL+ A+ DA Sbjct: 536 LHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAG 595 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEV-AKLNSQDEVVKLLE 187 K+ TPLH AA Y ++ LLL GA+ +G TP+ + AK N D LLE Sbjct: 596 KSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLE 652 Score = 63.9 bits (154), Expect = 4e-10 Identities = 34/115 (29%), Positives = 58/115 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A +G + + + GA+ + +V G ALH A G+ + L++ GA V+A Sbjct: 437 IHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKA 496 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K+ TPLH +A G+ + V LL+ GA+ G TP+ ++ ++V L Sbjct: 497 KDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/118 (32%), Positives = 55/118 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 VH A G + + L AN + + G LH A + AE+L+ GA VDA Sbjct: 668 VHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQT 727 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 K TPLH YG + V+ LL+H A V + +G TP+ A ++ +L Q+ Sbjct: 728 KMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQN 785 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/115 (33%), Positives = 57/115 (49%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H +A +G A+ +++ L GA+ + G LH + G A LL+ GA++ Sbjct: 503 LHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITT 562 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K TPLH AA YG+ E +LLL+ A+ G TP+ VA +V LL Sbjct: 563 KKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLL 617 Score = 60.8 bits (146), Expect = 4e-09 Identities = 36/117 (30%), Positives = 59/117 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G AE ++ + GA + + + + LH + G+ + LL+ GA+ +A Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAAT 529 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + TPLH +A G ++ LL HGA++ + G TP+ VA + EV LL Q Sbjct: 530 TSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQ 586 Score = 59.7 bits (143), Expect = 8e-09 Identities = 41/106 (38%), Positives = 58/106 (54%), Gaps = 3/106 (2%) Frame = -3 Query: 498 LKKALD---GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHY 328 L+KALD G + + + G ALH A G ++ LL+ A VDA K NT LH Sbjct: 54 LEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHI 113 Query: 327 AAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A+ G+ E V +L+ +GA V Q+ +G TP+ +A + EVVK L Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFL 159 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/97 (34%), Positives = 50/97 (51%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ D + G LH C YG +K LL+ A V+A KN TPLH AA G + Sbjct: 720 GAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHII 779 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 ++LL++ A+ ++G T + +A+ VV L+ Sbjct: 780 NVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 816 Score = 53.1 bits (126), Expect = 7e-07 Identities = 36/115 (31%), Positives = 49/115 (42%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E L A+ D G LH A Y K A +LL+ GA+ A Sbjct: 569 LHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAA 628 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN TPLH AA + + LL++GA G + +A ++V LL Sbjct: 629 KNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/115 (32%), Positives = 53/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G+A +K LD GA D + +G LH G + E+LL+ A + + Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKT 331 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN +PLH A CV LLL+H V D T + VA +V K+L Sbjct: 332 KNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 386 Score = 52.0 bits (123), Expect = 2e-06 Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 3/94 (3%) Frame = -3 Query: 462 EEDVEGR---RALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 E D +G+ ALH A + K A +LL+ D K+ TPLH AA YG L Sbjct: 194 ENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATL 253 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LL AAV + TP+ VA +VKLL Sbjct: 254 LLNRAAAVDFTARNDITPLHVASKRGNANMVKLL 287 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/99 (33%), Positives = 46/99 (46%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 LD GA+ G LH A ++ A LLE GA +A+ + +H AA G Sbjct: 618 LDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHV 677 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + V LLL A V L N G TP+ +A + V ++L Sbjct: 678 DMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVL 716 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/84 (32%), Positives = 45/84 (53%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A G ++LL+ GA +DA ++ TPLH A G ++ V++LL A ++ + Sbjct: 272 LHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKT 331 Query: 255 LDGKTPIEVAKLNSQDEVVKLLEQ 184 +G +P+ +A V+LL Q Sbjct: 332 KNGLSPLHMATQGDHLNCVQLLLQ 355 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/117 (28%), Positives = 52/117 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A + L+ GA+ + +G ++H A G + +LL A V+ + Sbjct: 635 LHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSN 694 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 K+ TPLH AA R ++L+ GA V Q G TP+ V ++V L Q Sbjct: 695 KSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 751 Score = 40.8 bits (94), Expect = 0.004 Identities = 25/85 (29%), Positives = 41/85 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G AE +K + GAN + + G L+ A L+ + LL+ GA+ Sbjct: 111 LHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLAT 170 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKH 280 ++ TPL A G + V LLL++ Sbjct: 171 EDGFTPLAVALQQGHDQVVSLLLEN 195
>ASB10_MOUSE (Q91ZT7) Ankyrin repeat and SOCS box protein 10 (ASB-10)| Length = 467 Score = 73.9 bits (180), Expect = 4e-13 Identities = 42/104 (40%), Positives = 59/104 (56%), Gaps = 1/104 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA-L 358 +H S G A ++ L GA+ + D +G+R LH G G L+C E+LL+ GA VD Sbjct: 152 LHEACSAGHAACVRVLLVAGADPNTLDQDGKRPLHLCRGPGILECVELLLKFGAQVDGRT 211 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 + + TPLH AA G E DLLL+ GA ++N +G TP+ A Sbjct: 212 EDEEETPLHIAARLGHVELADLLLRWGACPDVRNSEGWTPLLAA 255 Score = 68.6 bits (166), Expect = 2e-11 Identities = 47/116 (40%), Positives = 59/116 (50%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H AS G E L+ L A D GR ALH AC G C +LL AGA + LD Sbjct: 120 LHVAASRGHTEVLELLLRRRAKPDSAP-GGRTALHEACSAGHAACVRVLLVAGADPNTLD 178 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD-GKTPIEVAKLNSQDEVVKLL 190 ++ PLH G G ECV+LLLK GA V + D +TP+ +A E+ LL Sbjct: 179 QDGKRPLHLCRGPGILECVELLLKFGAQVDGRTEDEEETPLHIAARLGHVELADLL 234 Score = 47.4 bits (111), Expect = 4e-05 Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 16/135 (11%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKC--------------- 400 +H A +G E L GA D + EG L AC +++C Sbjct: 219 LHIAARLGHVELADLLLRWGACPDVRNSEGWTPLLAAC---DIRCQSPKDAEATTNRCFQ 275 Query: 399 -AEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 +LL GA DA +++K PLH A +G V LLL G + G TP+ A Sbjct: 276 LCRLLLSVGADADAANQDKQRPLHLACRHGHSAVVQLLLSCGVNANAMDYGGHTPLHCAL 335 Query: 222 LNSQDEVVKLLEQDV 178 L V E V Sbjct: 336 LGPTTAVAHSPEHTV 350
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 73.6 bits (179), Expect = 5e-13 Identities = 43/116 (37%), Positives = 58/116 (50%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A GD + L+ A+ +E D EGR +H AC +G+ ILL G V Sbjct: 556 LHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQG 615 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKH-GAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K+ PLHYAA G V LL K G +V Q LDG+TP+ +A V ++L Sbjct: 616 KDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARIL 671 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/117 (31%), Positives = 60/117 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++H G E K L AN + + G LH A E+LL +V+A Sbjct: 488 SLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNA 547 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D+++ T LH+AA G + LLL+ A+V + +G+TP+ VA + Q+ +V++L Sbjct: 548 KDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 604 Score = 57.8 bits (138), Expect = 3e-08 Identities = 32/90 (35%), Positives = 47/90 (52%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKH 280 +D + ALHFA G+ +LLE A+V+ +D TP+H A +G++ V +LL+ Sbjct: 548 KDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRR 607 Query: 279 GAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 G V LQ D P+ A +VKLL Sbjct: 608 GVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 637 Score = 53.1 bits (126), Expect = 7e-07 Identities = 32/99 (32%), Positives = 46/99 (46%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + + + ++GR LH A G + A IL++ + V+ TPLH AA G Sbjct: 642 GVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTA 701 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 LLL GA DG T + +A N VKLL ++ Sbjct: 702 RLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEE 740 Score = 39.3 bits (90), Expect = 0.011 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 5/113 (4%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVE-----GRRALHFACGYGELKCAEILLEAGAAVDALDKN 349 GD L K L +DV+ G LH A G+ +CA+ LL A + ++ Sbjct: 465 GDTSKLMKILQ------PQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRR 518 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +TPLH A + V+LLL +V ++ D T + A N + +LL Sbjct: 519 GSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLL 571
>ANR28_HUMAN (O15084) Ankyrin repeat domain-containing protein 28| Length = 1086 Score = 73.2 bits (178), Expect = 7e-13 Identities = 45/115 (39%), Positives = 59/115 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H+ A G E +K L GAN + D + RRA+H+A G ++ ++L+ GA V D Sbjct: 177 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKD 236 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K TPLH AA G V LL G + N G TP+ VA N QD VV L Sbjct: 237 KKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNEL 291 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/123 (29%), Positives = 62/123 (50%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 AS A L+ + GA+ + + +G+ LH +G ++ ++++GA +D DKN N Sbjct: 314 ASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGN 373 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SK 163 TPLH AA YG + ++ L+ GA + + G P+ +A L+ + + L F Sbjct: 374 TPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 433 Query: 162 PSD 154 P D Sbjct: 434 PDD 436 Score = 64.7 bits (156), Expect = 2e-10 Identities = 38/106 (35%), Positives = 57/106 (53%), Gaps = 3/106 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVE---GRRALHFACGYGELKCAEILLEAGAAVD 364 +H A+ G +E L+ + ++ D++ G+ L + G C LL GA VD Sbjct: 654 IHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVD 713 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 A DK T LH A G +ECVD LL+HGA +L++ G+TPI ++ Sbjct: 714 AKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLS 759 Score = 63.5 bits (153), Expect = 5e-10 Identities = 37/109 (33%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H AS G +K LD G + +E + G LH AC G+ L++ GA V+ + Sbjct: 243 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKN 302 Query: 354 KNKNTPLHYAAGYGRKE-CVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 + TPLH+AA C++LL+ +GA V +++ DGKTP+ + L+ + Sbjct: 303 EKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGR 351 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/109 (34%), Positives = 54/109 (49%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G ++ +K L G + D D GR LH A G L+C +LL GA + D Sbjct: 409 LHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD 468 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD 208 K +PLHYAA +C+ L+ GA+V + G TP+ A + D Sbjct: 469 KFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTD 517 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/95 (36%), Positives = 49/95 (51%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 +N + D GR ALH A G + ++LL GA ++A DK +H+AA G E V Sbjct: 164 SNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVK 223 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LL+ HGA V ++ TP+ A + VVK L Sbjct: 224 LLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 258 Score = 59.3 bits (142), Expect = 1e-08 Identities = 49/153 (32%), Positives = 62/153 (40%), Gaps = 38/153 (24%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEE----DVEGRRALHFACGYGELKCAEILLEA---- 379 +H +A+ G L L A+ D D G ALH+AC G C E+LLE Sbjct: 756 IHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQ 815 Query: 378 -------------------GAA-----------VDALDKNKNTPLHYAAGYGRKECVDLL 289 GAA V+A D TPLH AA EC+ LL Sbjct: 816 KTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLL 875 Query: 288 LKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L H A V + GKTP+ +A N Q V++L Sbjct: 876 LSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 908 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/115 (32%), Positives = 60/115 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A +GDAE ++ + GA + +D + LH A + ++LL+ A V+A D Sbjct: 78 LHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARD 137 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN TPLH AA +C + L+ + V + + G+T + A + E+VKLL Sbjct: 138 KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 192 Score = 57.4 bits (137), Expect = 4e-08 Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 4/143 (2%) Frame = -3 Query: 615 PVDAATSTVLSGPQXXXXXXXXXXESIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRA 436 P+D T SG S +H A G + L+ + + D + GR Sbjct: 562 PLDVLMET--SGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTP 619 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKN-KNTPLHYAAGYGRKECVDLLLKHGA---AV 268 L A G ++C ++L+ GA++ D K TP+H AA G EC+ LL+ + AV Sbjct: 620 LDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAV 679 Query: 267 MLQNLDGKTPIEVAKLNSQDEVV 199 +Q+ +G+TP+ ++ LN + V Sbjct: 680 DIQDGNGQTPLMLSVLNGHTDCV 702 Score = 57.4 bits (137), Expect = 4e-08 Identities = 33/99 (33%), Positives = 54/99 (54%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD + ++ + + + +D E R LH A G+ + E+L+ +GA V+A D TPL Sbjct: 52 GDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPL 111 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLN 217 H A +E V +LLKH A V ++ + +TP+ +A N Sbjct: 112 HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAAN 150 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/83 (33%), Positives = 49/83 (59%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A +G + E+L+++ +D + + TPL AA G ECVD+L+ GA++++++ Sbjct: 587 LHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKD 646 Query: 255 -LDGKTPIEVAKLNSQDEVVKLL 190 + +TPI A N E ++LL Sbjct: 647 YILKRTPIHAAATNGHSECLRLL 669 Score = 52.0 bits (123), Expect = 2e-06 Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 5/118 (4%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + + L+ GAN D +D GR ALH G +C + LL+ GA D TP+ Sbjct: 697 GHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPI 756 Query: 333 HYAAGYGRKECVDLLLKHGAAV----MLQNLDGKTPIEVAKLNSQDEVVK-LLEQDVF 175 H +A G + LL+ A++ + G T + A N + V+ LLEQ+VF Sbjct: 757 HLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVF 814 Score = 52.0 bits (123), Expect = 2e-06 Identities = 33/106 (31%), Positives = 48/106 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + + GA+ + + G LH A G C LL +G +D D Sbjct: 376 LHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPD 435 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLN 217 T LH AA G EC++LLL GA ++ G++P+ A N Sbjct: 436 DFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAAN 481 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/115 (31%), Positives = 52/115 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + E ++ L A+ + D + LH A +KCAE L+ + V+ D Sbjct: 111 LHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSD 170 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + T LH+AA G E V LLL GA + + + I A EVVKLL Sbjct: 171 RAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLL 225 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/125 (26%), Positives = 61/125 (48%), Gaps = 14/125 (11%) Frame = -3 Query: 522 ASVGDAEG--LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEIL--------LEAGA 373 A+ D +G L+ L AN D +G A+H++ YG C +++ L + Sbjct: 511 AATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETS 570 Query: 372 AVDALDKNKN----TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDE 205 D L + N +PLH AA +G + +++L++ + ++N G+TP+++A E Sbjct: 571 GTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 630 Query: 204 VVKLL 190 V +L Sbjct: 631 CVDVL 635 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/103 (30%), Positives = 52/103 (50%), Gaps = 4/103 (3%) Frame = -3 Query: 522 ASVGDAEGLKKALD---GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 A + D EG + L G + + D +GR LH A ++C ++LL A V+++D Sbjct: 828 AVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDS 887 Query: 351 NKNTPLHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVA 226 TPL AA G+ V++L+ +A + LQ+ T + +A Sbjct: 888 TGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLA 930 Score = 39.7 bits (91), Expect = 0.009 Identities = 22/60 (36%), Positives = 33/60 (55%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V+ D K TPLH AA G E ++LL+ GA V ++ TP+ A + +E V++L Sbjct: 67 VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVL 126 Score = 38.9 bits (89), Expect = 0.015 Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEA---GAAVDALDKNKNTPLHYAAGYGRKECVDLL 289 +D ALH AC G A ++LE ++A + TPLH AA G V L Sbjct: 919 QDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQEL 978 Query: 288 LKHGAAVMLQNLDGKTP 238 L GA+V+ + +G TP Sbjct: 979 LGKGASVLAVDENGYTP 995
>ASB10_HUMAN (Q8WXI3) Ankyrin repeat and SOCS box protein 10 (ASB-10)| Length = 429 Score = 72.8 bits (177), Expect = 9e-13 Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL- 358 +H + G + L GA+ + D +G+R LH G G L+CAE+LL GA VD Sbjct: 152 LHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRS 211 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 ++ + TPLH AA G E DLLL+ GA +N +G TP+ A Sbjct: 212 EEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAA 255 Score = 63.9 bits (154), Expect = 4e-10 Identities = 44/116 (37%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H AS G E L+ L A D GR ALH AC G C +LL AGA + D Sbjct: 120 LHVAASRGHTEVLRLLLRRRARPDSAP-GGRTALHEACAAGHTACVHVLLVAGADPNIAD 178 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAV-MLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ PLH G G EC +LLL+ GA V + +TP+ VA E+ LL Sbjct: 179 QDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLL 234 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/119 (31%), Positives = 50/119 (42%), Gaps = 16/119 (13%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEI------------ 391 +H A +G E L GA D + EG L AC +++C I Sbjct: 219 LHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAAC---DVRCQSITDAEATTARCLQ 275 Query: 390 ----LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 LL AGA DA D++K PLH A G V+LLL G + + G TP+ A Sbjct: 276 LCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCA 334
>LCTA_LATMA (Q9XZC0) Alpha-latrocrustotoxin (Alpha-LCT) (Crusta1)| Length = 1395 Score = 71.6 bits (174), Expect = 2e-12 Identities = 41/119 (34%), Positives = 65/119 (54%), Gaps = 1/119 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G+++ +K L+ GA D+E G ALH A + + L+ GA ++A Sbjct: 720 LHLAAATGNSQIVKTILNSGAVVDQETANGFTALHLAIMNPNTETPQFLIAKGANINAKT 779 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQD 181 + +TPLH+AA G+ LL+ GA + +NL + PI A +N +VK L+EQD Sbjct: 780 NDGSTPLHFAAALGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIVKMLIEQD 838 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAV-DAL 358 +H A++G + +D GAN E++ + +H A G L ++L+E +++ +A Sbjct: 786 LHFAAALGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIVKMLIEQDSSLMNAK 845 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 + P + AA K+ + L GA V +N DG T + + +N + EVV+ L Q+ Sbjct: 846 NMRDEYPFYLAAEKRYKDVFNYLESKGADVNEKNNDGNTLLHLFSINGEVEVVQFLIQN 904 Score = 43.1 bits (100), Expect = 8e-04 Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Frame = -3 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHYAAG 319 +K +D GA GR+++H + G A +LL + ++ DKN TPLH A+ Sbjct: 461 RKLIDSGAQVGASFEMGRKSIHASATAGNDDVARLLLAKNNGLLNVPDKNGYTPLHIASE 520 Query: 318 YGRKECVDLLLKHGAAVMLQNLDGK-TPIEVAKLNSQDEVVKLL 190 + V LL+ GA V ++ + TP+ +A +VK L Sbjct: 521 RKNNDFVKFLLEKGADVNVRTFANELTPLHLAARQDFTIIVKTL 564 Score = 42.7 bits (99), Expect = 0.001 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GAN + + +G LHFA G+ ++L++ GA + A + P+H A G V Sbjct: 772 GANINAKTNDGSTPLHFAAALGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIV 831 Query: 297 DLLLKHGAAVM-LQNLDGKTPIEVAKLNSQDEVVKLLE 187 +L++ +++M +N+ + P +A +V LE Sbjct: 832 KMLIEQDSSLMNAKNMRDEYPFYLAAEKRYKDVFNYLE 869 Score = 33.5 bits (75), Expect = 0.61 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 4/92 (4%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAV--DALDKNKNTPLHYAAGYGRKECVDLLL-KHG 277 G LH A L A++L+++ V + +D N TPLHYA+ G E V + G Sbjct: 612 GLTPLHLAVLQNNLSAAKVLVKSNKKVKLNEMDNNGMTPLHYASMLGNLEFVKYFTSEQG 671 Query: 276 AAVMLQ-NLDGKTPIEVAKLNSQDEVVKLLEQ 184 V + + TP+ +A L + +V + L Q Sbjct: 672 IDVNAKTKVKNWTPLHLAILFKKFDVAQSLLQ 703 Score = 32.3 bits (72), Expect = 1.4 Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 1/121 (0%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDALDKNKNTPLHYAA 322 L + GA+ +++ V G L A G+ + L+E V+ +K + TPLH AA Sbjct: 1076 LNYLIRNGADPNKK-VRGDPPLFIAAMIGQYDIVKSLVEQHKIDVNTRNKEQFTPLHAAA 1134 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLI 142 + V L++ GA V + + PI++A S+ ++ L + F PS I Sbjct: 1135 SNDHIDVVKYLIQKGADVNAKGDENLKPIDLAGEKSK-AYLRSLGRRFFRNESPSKSFEI 1193 Query: 141 D 139 D Sbjct: 1194 D 1194 Score = 32.0 bits (71), Expect = 1.8 Identities = 23/96 (23%), Positives = 38/96 (39%), Gaps = 2/96 (2%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + + ++ G LH + ++ E A ++ + TPLH A Sbjct: 569 GIDVNAKERAGFTPLHLSITSNSRAARTLINETPAGINIKSNSGLTPLHLAVLQNNLSAA 628 Query: 297 DLLLKHGAAVMLQNLD--GKTPIEVAKLNSQDEVVK 196 +L+K V L +D G TP+ A + E VK Sbjct: 629 KVLVKSNKKVKLNEMDNNGMTPLHYASMLGNLEFVK 664 Score = 30.8 bits (68), Expect = 4.0 Identities = 18/79 (22%), Positives = 36/79 (45%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ +E++ +G LH GE++ + L++ GA +K + + A +G V Sbjct: 872 GADVNEKNNDGNTLLHLFSINGEVEVVQFLIQNGADFRLRNKERKSFFDLAVEFGHAGIV 931 Query: 297 DLLLKHGAAVMLQNLDGKT 241 ++ + + GKT Sbjct: 932 GYAIEENKVDLQEPYRGKT 950
>CSKI2_HUMAN (Q8WXE0) Caskin-2| Length = 1202 Score = 71.2 bits (173), Expect = 3e-12 Identities = 43/96 (44%), Positives = 55/96 (57%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + +D +G ALH A G L+ +LLEA A VD D N PLHYAA GR E V L Sbjct: 41 NVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRL 100 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LL+ AAV +LDG+ P+ +A EV ++L Q Sbjct: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQ 136 Score = 70.5 bits (171), Expect = 4e-12 Identities = 43/117 (36%), Positives = 63/117 (53%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H+ A G E + L+ A D +D G R LH+A G L+ +LL A AAV+A Sbjct: 51 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNA 110 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + PLH AA YG E ++LL+H + L N KTP+++A + +V +LL Sbjct: 111 ASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL 167 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E ++ L A + ++G+ LH A YG + +E+LL+ + ++ Sbjct: 86 LHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVN 145 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGK--------TPIEVAKLNSQDEVV 199 K K TPL A +GR + LLL V L + K TP+ +A N EV+ Sbjct: 146 KAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVI 205 Query: 198 KLL 190 + L Sbjct: 206 RQL 208 Score = 44.7 bits (104), Expect = 3e-04 Identities = 32/102 (31%), Positives = 48/102 (47%) Frame = -3 Query: 489 ALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 AL G KD D LH A G + LL AG ++ K T LH AA YG+ Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKT-GTALHEAALYGK 233 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 E V LLL+ G V ++N +T +++ + + + ++Q Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQ 275
>CSKI2_MOUSE (Q8VHK1) Caskin-2| Length = 1201 Score = 70.9 bits (172), Expect = 3e-12 Identities = 43/96 (44%), Positives = 55/96 (57%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + +D +G ALH A G L+ +LLEA A VD D N PLHYAA GR E V L Sbjct: 41 NINYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRL 100 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LL+ AAV +LDG+ P+ +A EV ++L Q Sbjct: 101 LLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQ 136 Score = 69.7 bits (169), Expect = 8e-12 Identities = 43/117 (36%), Positives = 63/117 (53%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H+ A G E + L+ A D +D G R LH+A G L+ +LL A AAV+A Sbjct: 51 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNA 110 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + PLH AA YG E ++LL+H + L N KTP+++A + +V +LL Sbjct: 111 ASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLL 167 Score = 55.5 bits (132), Expect = 1e-07 Identities = 42/123 (34%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEA-------- 379 +H A G E + L +N + + L AC +G LK A++LL + Sbjct: 119 LHLAAQYGHYEVSEMLLQHQSNPCLVNKLKKTPLDLACEFGRLKVAQLLLNSHLCVALLE 178 Query: 378 GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVV 199 G A D D N TPLH AA G +E + LLK G + Q G T + A L + EVV Sbjct: 179 GEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKTG-TALHEAALYGKTEVV 237 Query: 198 KLL 190 +LL Sbjct: 238 RLL 240 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E ++ L A + ++G+ LH A YG + +E+LL+ + ++ Sbjct: 86 LHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVN 145 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGK--------TPIEVAKLNSQDEVV 199 K K TPL A +GR + LLL V L + K TP+ +A N EV+ Sbjct: 146 KLKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVI 205 Query: 198 KLL 190 + L Sbjct: 206 RQL 208 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/102 (31%), Positives = 49/102 (48%) Frame = -3 Query: 489 ALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 AL G KD D LH A G + LL+AG ++ K T LH AA YG+ Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKAGIEINRQTKT-GTALHEAALYGK 233 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 E V LLL+ G V ++N +T +++ + + + ++Q Sbjct: 234 TEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQ 275
>KRIT1_MOUSE (Q6S5J6) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein homolog) Length = 736 Score = 70.5 bits (171), Expect = 4e-12 Identities = 46/136 (33%), Positives = 74/136 (54%), Gaps = 5/136 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDAL 358 +H A GD+E L LD G + ++ D + +H+AC YG+++ ILLE G + L Sbjct: 292 LHRNACEGDSELLSHLLDKGLSVNQLDNDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKH-GAAVMLQNLDGKTPIEVAKLNSQ---DEVVKLL 190 + ++PLH+AAG G E V +LL H + + G++P+ V + N Q +E KLL Sbjct: 352 NGQLSSPLHFAAGGGHAEIVQILLTHPDIDRHITDQQGRSPLNVCEENKQNNWEEAAKLL 411 Query: 189 EQDVFL*SKPSDPVLI 142 + + +KP + V I Sbjct: 412 KDAI---NKPYEKVRI 424
>INVS_BRARE (Q8UVC1) Inversin| Length = 1021 Score = 70.1 bits (170), Expect = 6e-12 Identities = 43/117 (36%), Positives = 61/117 (52%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S VH A GD L K + A +D ED GR L + L CAE+LL+AGA ++ Sbjct: 10 SQVHAAAVNGDKNTLHKLITESALRDSEDQFGRTPLMYCVLADRLDCAEVLLKAGAGINK 69 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D ++ T LH AA G + LLL A L++L+ TP+ +A +S + + LL Sbjct: 70 TDHSQRTALHLAAQKGNVRFMKLLLSRHADWRLKDLEEMTPLHLASRHSSSKPLSLL 126 Score = 62.8 bits (151), Expect = 9e-10 Identities = 36/109 (33%), Positives = 59/109 (54%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G + + + GGA D D++G ALH+A G + E+L+E G + + D+ TP Sbjct: 393 MGHRDVILTLIKGGARVDLVDIDGHSALHWAALGGNAEVCEVLMENGISPNLQDQAGRTP 452 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA G C+ LL++H A +Q+ +G+T + + N + VKLL Sbjct: 453 LQCAAYAGYINCMALLIQHDADPNIQDKEGRTALHWSCNNGYLDAVKLL 501 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/92 (36%), Positives = 49/92 (53%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A G + +LLE G VD LD K+TPL A G ++ + L+K G Sbjct: 347 DKYGGTALHAAALSGHVSTVRLLLEQGGMVDPLDVMKHTPLFRACEMGHRDVILTLIKGG 406 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 A V L ++DG + + A L EV ++L ++ Sbjct: 407 ARVDLVDIDGHSALHWAALGGNAEVCEVLMEN 438 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 2/115 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--AGAAVDA 361 +H A G+ +K L A+ +D+E LH A + K +LL+ A VD Sbjct: 78 LHLAAQKGNVRFMKLLLSRHADWRLKDLEEMTPLHLASRHSSSKPLSLLLKHMAPGEVDT 137 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 D+NK T LH++A Y E V LL+KH + + + + +GK P+ A N + Sbjct: 138 QDRNKQTALHWSAFYNHPEHVKLLIKHDSNIGIPDSEGKIPLHWAAHNKHPNATR 192 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/117 (29%), Positives = 57/117 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G ++ L+ G D DV L AC G L++ GA VD +D Sbjct: 354 LHAAALSGHVSTVRLLLEQGGMVDPLDVMKHTPLFRACEMGHRDVILTLIKGGARVDLVD 413 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + ++ LH+AA G E ++L+++G + LQ+ G+TP++ A + LL Q Sbjct: 414 IDGHSALHWAALGGNAEVCEVLMENGISPNLQDQAGRTPLQCAAYAGYINCMALLIQ 470 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/119 (29%), Positives = 56/119 (47%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G+AE + ++ G + + +D GR L A G + C +L++ A + Sbjct: 418 SALHWAALGGNAEVCEVLMENGISPNLQDQAGRTPLQCAAYAGYINCMALLIQHDADPNI 477 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAV--MLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK T LH++ G + V LLL GA M + TP++ A L E+ + L Sbjct: 478 QDKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHMEHTEERYTPLDYALLGEHQELTQFL 536 Score = 49.3 bits (116), Expect = 1e-05 Identities = 35/94 (37%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLE-AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLK 283 +D EGR LHFA G E+L G +V A D TPLH+AA G + V LLL+ Sbjct: 210 QDYEGRTPLHFAVADGNEAVVEVLTSYEGCSVTAYDNLFRTPLHWAALLGHAKIVHLLLE 269 Query: 282 HGAAVML-QNLDGKTPIEV-AKLNSQDEVVKLLE 187 + M+ + G TP+ A+ N D V L+ Sbjct: 270 RNKSGMIPSDSQGATPLHYGAQSNFADTVAVFLK 303 Score = 46.6 bits (109), Expect = 7e-05 Identities = 26/69 (37%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD--KNKNTPLHYAAGYGRKEC 301 A+ + +D EGR ALH++C G L ++LL GA + ++ + + TPL YA +E Sbjct: 473 ADPNIQDKEGRTALHWSCNNGYLDAVKLLLGCGAFPNHMEHTEERYTPLDYALLGEHQEL 532 Query: 300 VDLLLKHGA 274 LL+HGA Sbjct: 533 TQFLLEHGA 541 Score = 40.4 bits (93), Expect = 0.005 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAG-AAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 R LH+A G K +LLE + + D TPLHY A + V + LKH + Sbjct: 249 RTPLHWAALLGHAKIVHLLLERNKSGMIPSDSQGATPLHYGAQSNFADTVAVFLKHHSVR 308 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +L+G+T A ++V+K++ Sbjct: 309 DEPDLEGRTAFMWAAGKGSNDVIKIM 334 Score = 29.6 bits (65), Expect = 8.8 Identities = 21/91 (23%), Positives = 37/91 (40%), Gaps = 2/91 (2%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLL--LK 283 D +G LH+ + L+ + D D T +AAG G + + ++ LK Sbjct: 279 DSQGATPLHYGAQSNFADTVAVFLKHHSVRDEPDLEGRTAFMWAAGKGSNDVIKIMLDLK 338 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + + G T + A L+ V+LL Sbjct: 339 KDIDINMTDKYGGTALHAAALSGHVSTVRLL 369
>ANK2_HUMAN (Q01484) Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin,| nonerythroid) Length = 3924 Score = 70.1 bits (170), Expect = 6e-12 Identities = 39/115 (33%), Positives = 59/115 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A +G + L GA+ D ++ G ALH A G+++ LL GA VDA Sbjct: 435 IHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARA 494 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + TPLH A+ G+ E V LLL+H A +G TP+ ++ Q +V +L Sbjct: 495 REEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVL 549 Score = 67.8 bits (164), Expect = 3e-11 Identities = 40/115 (34%), Positives = 62/115 (53%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G K LD AN + + G LH AC +K E+L++ GA++ A+ Sbjct: 369 LHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAIT 428 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ TP+H AA G V LLL++GA+ + N+ G+T + +A Q EVV+ L Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 483 Score = 65.1 bits (157), Expect = 2e-10 Identities = 39/115 (33%), Positives = 58/115 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H +A G + L+ GA +G LH A YG L A++LL+ AA D+ Sbjct: 534 LHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG 593 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN TPLH AA Y ++ LLL+ GA+ +G TP+ +A +Q ++ L Sbjct: 594 KNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTL 648 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/86 (41%), Positives = 46/86 (53%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G LH A YG + A +LL GAAVD +N TPLH A+ G V LLL G + Sbjct: 233 GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQI 292 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 + DG TP+ A + D+VV+LL Sbjct: 293 DAKTRDGLTPLHCAARSGHDQVVELL 318 Score = 63.5 bits (153), Expect = 5e-10 Identities = 37/97 (38%), Positives = 50/97 (51%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA++D G L AC YG +K LL+ GA V+A KN TPLH AA G + Sbjct: 718 GADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHII 777 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 ++LL+HGA +G T + +AK VV L+ Sbjct: 778 NVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLK 814 Score = 63.2 bits (152), Expect = 7e-10 Identities = 38/111 (34%), Positives = 61/111 (54%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A G+ + + + L GG + + + G ALH A G + + LL G++VD+ K N Sbjct: 39 ARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGN 98 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LH A+ G+ E V +L+K GA + Q+ +G TP+ +A + +VVK L Sbjct: 99 TALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYL 149 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/115 (34%), Positives = 55/115 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + +G E ++ L A+ D G LH + G++ A +LLEAGAA Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 560 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K TPLH AA YG + LLL+ AA +G TP+ VA +V LL Sbjct: 561 KKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLL 615 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/132 (31%), Positives = 62/132 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G+ L+ GA D G LH A G ++LL+ G +DA Sbjct: 237 LHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKT 296 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 ++ TPLH AA G + V+LLL+ GA ++ + +G +P+ +A E VK L Q Sbjct: 297 RDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQH-- 354 Query: 174 L*SKPSDPVLID 139 P D V +D Sbjct: 355 --KAPVDDVTLD 364 Score = 61.2 bits (147), Expect = 3e-09 Identities = 39/115 (33%), Positives = 51/115 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + K L A D G LH A Y K A +LLE GA+ A Sbjct: 567 LHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATA 626 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN TPLH AA + + LL +GA + G TP+ +A ++V LL Sbjct: 627 KNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 681 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/117 (35%), Positives = 57/117 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E ++ L GA D E + LH A G+ + ++LL+ A DA Sbjct: 468 LHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAAT 527 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 N TPLH +A G+ + +LL+ GAA L G TP+ VA +V KLL Q Sbjct: 528 TNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ 584 Score = 60.1 bits (144), Expect = 6e-09 Identities = 43/115 (37%), Positives = 55/115 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G+ +K LD G D + +G LH A G + E+LLE GA + A Sbjct: 270 LHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLART 329 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN +PLH AA ECV LL+H A V LD T + VA V KLL Sbjct: 330 KNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 384 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/117 (32%), Positives = 55/117 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G + + LD GAN G +LH A ++ A+IL + GA DA Sbjct: 666 LHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHT 725 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 K TPL A YG + V+ LLK GA V + +G TP+ A ++ +L Q Sbjct: 726 KLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQ 782 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G +++ L G++ D +G ALH A G+ + ++L++ GA ++A Sbjct: 68 LHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQS 127 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQD 181 +N TPL+ AA + V LL++GA DG TP+ VA ++ V LLE D Sbjct: 128 QNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEND 186 Score = 56.2 bits (134), Expect = 9e-08 Identities = 39/120 (32%), Positives = 58/120 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A E +K L A D+ ++ ALH A G + ++LL+ A +A Sbjct: 334 SPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNA 393 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 N TPLH A R + ++LL+K+GA++ G TPI VA +V LL Q+ Sbjct: 394 RALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQN 453 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/99 (30%), Positives = 45/99 (45%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ GA+ G LH A +++ A LL GA + + K TPLH A+ G Sbjct: 616 LEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHT 675 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + V LLL GA + + G T + +A + V +L Sbjct: 676 DMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADIL 714 Score = 43.1 bits (100), Expect = 8e-04 Identities = 31/103 (30%), Positives = 43/103 (41%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A + L+ GA + +G LH A G +LL+ GA + Sbjct: 633 LHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST 692 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 K+ T LH AA + D+L KHGA G TP+ VA Sbjct: 693 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVA 735
>ANKR5_HUMAN (Q9NU02) Ankyrin repeat domain-containing protein 5| Length = 776 Score = 69.3 bits (168), Expect = 1e-11 Identities = 43/130 (33%), Positives = 70/130 (53%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G+ + +K L+ GAN + D LHFAC G+ E+L+E+GA +DA N +TPL Sbjct: 536 GNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPL 595 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSD 154 + A R + V LL GA L+N G + ++VAK + ++ L+++ + KP++ Sbjct: 596 NRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAE 655 Query: 153 PVLIDPKTLP 124 + KT P Sbjct: 656 NQKLKGKTPP 665 Score = 66.2 bits (160), Expect = 8e-11 Identities = 39/117 (33%), Positives = 62/117 (52%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S ++ GD LKKA + G D +D + L AC G + + LLE GA V+A Sbjct: 494 SNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNA 553 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D TPLH+A G+++ V+LL++ GA + +++ TP+ A + + + VK L Sbjct: 554 TDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYL 610 Score = 54.7 bits (130), Expect = 3e-07 Identities = 40/135 (29%), Positives = 60/135 (44%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E ++ L+ G + D + A HFA G ++L V + N NTPL Sbjct: 196 GVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPL 255 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSD 154 HYAA G +C + + G + +NLD KTP VAK K + + + +K + Sbjct: 256 HYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLAR 315 Query: 153 PVLIDPKTLPCFWSL 109 P +P L W+L Sbjct: 316 PGAKNPNPL---WAL 327 Score = 44.7 bits (104), Expect = 3e-04 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = -3 Query: 486 LDGGANKDE-EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 L+ GAN + GR AL A G ++ +LE G V+A D +++ H+AA G Sbjct: 171 LEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGF 230 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + + LL + V L +++G TP+ A + + K + Q Sbjct: 231 FDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQ 272
>PSD10_HUMAN (O75832) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 226 Score = 69.3 bits (168), Expect = 1e-11 Identities = 41/104 (39%), Positives = 55/104 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H AS E L+GGAN D +D A+H A G LK ILL A+ + D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 169 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 NTPLH A R E LL+ GA++ ++N + KTP++VAK Sbjct: 170 TEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213 Score = 64.7 bits (156), Expect = 2e-10 Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 1/117 (0%) Frame = -3 Query: 537 IVHNTASVGDAEGLKKALDGGAN-KDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +V N A G E LK+++ + D + R ALH+AC G + E LL+ G V+ Sbjct: 9 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D +PLH AA GR E V LL GA V N +G TP+ A ++ E+ +L Sbjct: 69 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125 Score = 62.8 bits (151), Expect = 9e-10 Identities = 40/117 (34%), Positives = 60/117 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H AS G E +K L GA + + G LH+A + A +LLE GA DA Sbjct: 75 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D + T +H AA G + + +LL + A+ +Q+ +G TP+ +A + E KLL Sbjct: 135 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191 Score = 53.5 bits (127), Expect = 6e-07 Identities = 36/106 (33%), Positives = 52/106 (49%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H S G E ++ L G +++D G LH A G + + LL GA V+A++ Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 103 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLN 217 +N TPLHYAA R E +LL+ GA N D K E ++ Sbjct: 104 QNGCTPLHYAASKNRHEIAVMLLEGGA-----NPDAKDHYEATAMH 144 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/72 (30%), Positives = 39/72 (54%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G+ + + L A+ + +D EG LH AC ++ A++L+ GA++ + Sbjct: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIEN 202 Query: 354 KNKNTPLHYAAG 319 K + TPL A G Sbjct: 203 KEEKTPLQVAKG 214
>ANK1_MOUSE (Q02357) Ankyrin-1 (Erythrocyte ankyrin)| Length = 1862 Score = 68.9 bits (167), Expect = 1e-11 Identities = 40/118 (33%), Positives = 61/118 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G K LD GA + + G LH AC ++ E+LL+ GA++DA+ Sbjct: 338 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVT 397 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 ++ TPLH A+ G V LL+ GA+ + N+ +TP+ +A EV K L Q+ Sbjct: 398 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 455 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/115 (34%), Positives = 58/115 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A +G +K L+ GA+ + G LH A G + A LLE A+ + Sbjct: 470 LHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKEASQACMT 529 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K TPLH AA YG+ +LLL+H A +G TP+ VA ++ ++VKLL Sbjct: 530 KKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 584 Score = 60.5 bits (145), Expect = 5e-09 Identities = 39/117 (33%), Positives = 58/117 (49%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + L+ A++ +G LH A YG+++ AE+LLE A +A Sbjct: 503 LHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELLLEHDAHPNAAG 562 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 KN TPLH A + + V LLL G + +G TP+ +A +Q EV + L Q Sbjct: 563 KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQ 619 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/115 (33%), Positives = 58/115 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G+ ++ LD GA + + LH A G ++ +EILL+ GA + A Sbjct: 239 LHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 298 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN +P+H AA +CV LLL++ A + LD TP+ VA V K+L Sbjct: 299 KNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 353 Score = 58.5 bits (140), Expect = 2e-08 Identities = 39/119 (32%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + +G +K L GA+ + +V+ LH A G + A+ LL+ A +A Sbjct: 404 LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKANAKA 463 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ-DEVVKLLEQD 181 K+ TPLH AA G V LLL++GA+ L G TP+ A D + LLE++ Sbjct: 464 KDDQTPLHCAARIGHTGMVKLLLENGASPNLATTAGHTPLHTAAREGHVDTALALLEKE 522 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/115 (31%), Positives = 54/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E + L AN + + G LH G + A++L++ G VDA Sbjct: 635 LHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVLIKHGVTVDATT 694 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPLH A+ YG + V LL+H A V + G +P+ A ++V LL Sbjct: 695 RMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 749 Score = 56.6 bits (135), Expect = 7e-08 Identities = 33/101 (32%), Positives = 52/101 (51%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ GA+ + G LH A G + +LL+ GA ++ K++ TPLH AA G Sbjct: 222 LNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHV 281 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 ++LL HGA + + +G +PI +A + V+LL Q Sbjct: 282 RISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 322 Score = 55.8 bits (133), Expect = 1e-07 Identities = 37/115 (32%), Positives = 50/115 (43%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A D L N D G LH A Y L A++LL GA+V+ Sbjct: 173 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 232 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N TPLH A+ G V LLL GA + + D TP+ A N + ++L Sbjct: 233 QNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDELTPLHCAARNGHVRISEIL 287 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/85 (38%), Positives = 45/85 (52%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G D G LH A YG +K + LL+ A V+A K +PLH AA G + V Sbjct: 687 GVTVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIV 746 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAK 223 LLLK+GA+ + +G TP+ +AK Sbjct: 747 TLLLKNGASPNEVSSNGTTPLAIAK 771 Score = 55.1 bits (131), Expect = 2e-07 Identities = 36/117 (30%), Positives = 52/117 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A E + L G + + E V+G LH A G + +LL A + + Sbjct: 602 LHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGN 661 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 K+ TPLH + G D+L+KHG V G TP+ VA ++VK L Q Sbjct: 662 KSGLTPLHLVSQEGHVPVADVLIKHGVTVDATTRMGYTPLHVASHYGNIKLVKFLLQ 718 Score = 52.8 bits (125), Expect = 1e-06 Identities = 35/115 (30%), Positives = 52/115 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + LD GA + G +H A L C +LL+ A +D + Sbjct: 272 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYNAEIDDIT 331 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPLH AA G +LL GA + L+G TP+ +A + V++LL Sbjct: 332 LDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHIRVMELL 386 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/119 (30%), Positives = 55/119 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A + ++ L A D+ ++ LH A G + A++LL+ GA ++ Sbjct: 303 SPIHMAAQGDHLDCVRLLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 362 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 N TPLH A ++LLLK GA++ G TP+ VA +VK L Q Sbjct: 363 RALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 421 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = -3 Query: 498 LKKALD---GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHY 328 L KALD G + + + G LH A G +K LL ++ K NT LH Sbjct: 21 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 80 Query: 327 AAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 AA G+ E V L+ +GA V Q+ G TP+ +A + EVVK L Sbjct: 81 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 126 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/83 (36%), Positives = 40/83 (48%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 ALH A + + A +LL+ D L K TPLH AA Y LLL GA+V Sbjct: 172 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 231 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 +G TP+ +A +V+LL Sbjct: 232 PQNGITPLHIASRRGNVIMVRLL 254 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/115 (27%), Positives = 52/115 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + L+ A+ + G LH A + L ++LL G + + Sbjct: 536 LHVAAKYGKVRLAELLLEHDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA 595 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 N TPLH AA + E LL++G + +++ G TP+ +A E+V LL Sbjct: 596 WNGYTPLHIAAKQNQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALL 650 Score = 46.2 bits (108), Expect = 9e-05 Identities = 33/115 (28%), Positives = 50/115 (43%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E K L A + + + + LH A G ++LLE GA+ + Sbjct: 437 LHMAARAGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLAT 496 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +TPLH AA G + LL+ A+ G TP+ VA + + +LL Sbjct: 497 TAGHTPLHTAAREGHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELL 551 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/84 (35%), Positives = 42/84 (50%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G ALH A G+ + L+ GA V+A + TPL+ AA E V LL++GA Sbjct: 73 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 132 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVV 199 + DG TP+ VA + VV Sbjct: 133 QNVATEDGFTPLAVALQQGHENVV 156 Score = 45.4 bits (106), Expect = 2e-04 Identities = 34/117 (29%), Positives = 48/117 (41%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 ++ HN + +K L G + G LH A +++ A LL+ G + +A Sbjct: 572 AVHHNNLDI-----VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQIEVARSLLQYGGSANA 626 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPLH AA G E V LLL A L N G TP+ + V +L Sbjct: 627 ESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNKSGLTPLHLVSQEGHVPVADVL 683 Score = 39.3 bits (90), Expect = 0.011 Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 29/144 (20%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E +++ ++ GAN + + +G L+ A L+ + LLE GA + Sbjct: 78 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 137 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHG---------------------AAVMLQN------ 256 ++ TPL A G + V L+ +G AAV+LQN Sbjct: 138 EDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDV 197 Query: 255 --LDGKTPIEVAKLNSQDEVVKLL 190 G TP+ +A V +LL Sbjct: 198 LSKTGFTPLHIAAHYENLNVAQLL 221
>ANK1_HUMAN (P16157) Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R)| Length = 1880 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/118 (33%), Positives = 61/118 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G K LD GA + + G LH AC ++ E+LL+ GA++DA+ Sbjct: 341 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVT 400 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 ++ TPLH A+ G V LL+ GA+ + N+ +TP+ +A EV K L Q+ Sbjct: 401 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQN 458 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/115 (33%), Positives = 56/115 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A +G +K L+ AN + G LH A G ++ LLE A+ + Sbjct: 473 LHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMT 532 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K TPLH AA YG+ +LLL+ A +G TP+ VA ++ ++VKLL Sbjct: 533 KKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLL 587 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/117 (34%), Positives = 59/117 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E + L+ A++ +G LH A YG+++ AE+LLE A +A Sbjct: 506 LHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAG 565 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 KN TPLH A + + V LLL G + +G TP+ +A +Q EV + L Q Sbjct: 566 KNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQ 622 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/115 (33%), Positives = 59/115 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G+ ++ LD GA + + + LH A G ++ +EILL+ GA + A Sbjct: 242 LHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKT 301 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 KN +P+H AA +CV LLL++ A + LD TP+ VA V K+L Sbjct: 302 KNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 356 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/115 (32%), Positives = 55/115 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G AE + L AN + + G LH G + A++L++ G VDA Sbjct: 638 LHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATT 697 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPLH A+ YG + V LL+H A V + G +P+ A ++V LL Sbjct: 698 RMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 752 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + +G +K L GA+ + +V+ LH A G + A+ LL+ A V+A Sbjct: 407 LHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKA 466 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDE-VVKLLEQD 181 K+ TPLH AA G V LLL++ A L G TP+ +A E V+ LLE++ Sbjct: 467 KDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKE 525 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/104 (35%), Positives = 50/104 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + G D G LH A YG +K + LL+ A V+A Sbjct: 671 LHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 730 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 K +PLH AA G + V LLLK+GA+ + DG TP+ +AK Sbjct: 731 KLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAK 774 Score = 56.6 bits (135), Expect = 7e-08 Identities = 33/101 (32%), Positives = 52/101 (51%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ GA+ + G LH A G + +LL+ GA ++ K++ TPLH AA G Sbjct: 225 LNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHV 284 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 ++LL HGA + + +G +PI +A + V+LL Q Sbjct: 285 RISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQ 325 Score = 56.2 bits (134), Expect = 9e-08 Identities = 37/117 (31%), Positives = 52/117 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A E + L G + + E V+G LH A G + +LL A + + Sbjct: 605 LHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGN 664 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 K+ TPLH A G D+L+KHG V G TP+ VA ++VK L Q Sbjct: 665 KSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQ 721 Score = 55.8 bits (133), Expect = 1e-07 Identities = 37/115 (32%), Positives = 50/115 (43%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A D L N D G LH A Y L A++LL GA+V+ Sbjct: 176 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 235 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N TPLH A+ G V LLL GA + + D TP+ A N + ++L Sbjct: 236 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEIL 290 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/115 (30%), Positives = 52/115 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + LD GA + G +H A L C +LL+ A +D + Sbjct: 275 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 334 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPLH AA G +LL GA + L+G TP+ +A + V++LL Sbjct: 335 LDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELL 389 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/119 (30%), Positives = 55/119 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A + ++ L A D+ ++ LH A G + A++LL+ GA ++ Sbjct: 306 SPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 365 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 N TPLH A ++LLLK GA++ G TP+ VA +VK L Q Sbjct: 366 RALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQ 424 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/106 (35%), Positives = 51/106 (48%), Gaps = 3/106 (2%) Frame = -3 Query: 498 LKKALD---GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHY 328 L KALD G + + + G LH A G +K LL ++ K NT LH Sbjct: 24 LDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHI 83 Query: 327 AAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 AA G+ E V L+ +GA V Q+ G TP+ +A + EVVK L Sbjct: 84 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 129 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/115 (27%), Positives = 52/115 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + L+ A+ + G LH A + L ++LL G + + Sbjct: 539 LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPA 598 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 N TPLH AA + E LL++G + +++ G TP+ +A E+V LL Sbjct: 599 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALL 653 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/83 (36%), Positives = 40/83 (48%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 ALH A + + A +LL+ D L K TPLH AA Y LLL GA+V Sbjct: 175 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 234 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 +G TP+ +A +V+LL Sbjct: 235 PQNGITPLHIASRRGNVIMVRLL 257 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/115 (30%), Positives = 49/115 (42%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E K L A + + + + LH A G ++LLE A + Sbjct: 440 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLAT 499 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +TPLH AA G E V LL+ A+ G TP+ VA + V +LL Sbjct: 500 TAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELL 554 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/84 (35%), Positives = 42/84 (50%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G ALH A G+ + L+ GA V+A + TPL+ AA E V LL++GA Sbjct: 76 KGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 135 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVV 199 + DG TP+ VA + VV Sbjct: 136 QNVATEDGFTPLAVALQQGHENVV 159 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/117 (29%), Positives = 48/117 (41%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 ++ HN + +K L G + G LH A +++ A LL+ G + +A Sbjct: 575 AVHHNNLDI-----VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANA 629 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPLH AA G E V LLL A L N G TP+ + V +L Sbjct: 630 ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVL 686 Score = 39.3 bits (90), Expect = 0.011 Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 29/144 (20%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E +++ ++ GAN + + +G L+ A L+ + LLE GA + Sbjct: 81 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVAT 140 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHG---------------------AAVMLQN------ 256 ++ TPL A G + V L+ +G AAV+LQN Sbjct: 141 EDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDV 200 Query: 255 --LDGKTPIEVAKLNSQDEVVKLL 190 G TP+ +A V +LL Sbjct: 201 LSKTGFTPLHIAAHYENLNVAQLL 224
>CSKI1_HUMAN (Q8WXD9) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 68.6 bits (166), Expect = 2e-11 Identities = 46/130 (35%), Positives = 68/130 (52%), Gaps = 5/130 (3%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + +D +G ALH A G + +LLEA AAVD D PLHYAA GRKE + L Sbjct: 41 NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID-----PKTL 127 +LK G+AV + + +G P+ +A + +V ++L Q S+P ++D P L Sbjct: 101 VLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQ------HQSNPCMVDNSGKTPLDL 154 Query: 126 PCFWSLSGAM 97 C + G + Sbjct: 155 ACEFGRVGVV 164 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/117 (32%), Positives = 67/117 (57%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H+ A G+ E + L+ A D +D +G R LH+A G + +++L+AG+AV+ Sbjct: 51 SALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNI 110 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + PLH AA +G + ++LL+H + + + GKTP+++A + VV+LL Sbjct: 111 PSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167 Score = 49.3 bits (116), Expect = 1e-05 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 8/125 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E +K L G+ + EG LH A +G +E+LL+ + +D Sbjct: 86 LHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD 145 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVML--------QNLDGKTPIEVAKLNSQDEVV 199 + TPL A +GR V LLL L + +G +P+ +A N +++ Sbjct: 146 NSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDII 205 Query: 198 KLLEQ 184 +LL Q Sbjct: 206 RLLLQ 210 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/123 (30%), Positives = 55/123 (44%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAV---- 367 +H A G + + L +N D G+ L AC +G + ++LL + Sbjct: 119 LHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLE 178 Query: 366 ----DALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVV 199 DA D N +PLH AA G + + LLL+ G + Q G T + A L + EVV Sbjct: 179 PRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVV 237 Query: 198 KLL 190 +LL Sbjct: 238 RLL 240
>KRIT1_HUMAN (O00522) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein) Length = 736 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/136 (31%), Positives = 75/136 (55%), Gaps = 5/136 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDAL 358 +H +A GD+E L + L + ++ D + +H+AC YG+++ ILLE G + L Sbjct: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVM-LQNLDGKTPIEVAKLNSQ---DEVVKLL 190 + ++PLH+AAG G E V +LL H + + G++P+ + + N Q +E KLL Sbjct: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411 Query: 189 EQDVFL*SKPSDPVLI 142 ++ + +KP + V I Sbjct: 412 KEAI---NKPYEKVRI 424
>KRIT1_BOVIN (Q6TNJ1) Krev interaction trapped protein 1 (Krev interaction| trapped 1) (Cerebral cavernous malformations 1 protein homolog) Length = 736 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/136 (31%), Positives = 76/136 (55%), Gaps = 5/136 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDAL 358 +H +A GD+E L + L+ + ++ D + +H+AC YG+++ ILLE G + L Sbjct: 292 LHRSACEGDSELLNRLLNERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVM-LQNLDGKTPIEVAKLNSQ---DEVVKLL 190 + ++PLH+AAG G E V +LL H + + G++P+ + + N Q +E KLL Sbjct: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPEIDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411 Query: 189 EQDVFL*SKPSDPVLI 142 ++ + +KP + V I Sbjct: 412 KEAI---NKPYEKVRI 424
>CSKI1_RAT (Q8VHK2) Caskin-1 (CASK-interacting protein 1)| Length = 1430 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/130 (35%), Positives = 68/130 (52%), Gaps = 5/130 (3%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + +D +G ALH A G + +LLEA AAVD D PLHYAA GRKE + L Sbjct: 41 NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID-----PKTL 127 +LK G+AV + + +G P+ +A + +V ++L Q S+P ++D P L Sbjct: 101 VLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQ------HQSNPCIVDNSGKTPLDL 154 Query: 126 PCFWSLSGAM 97 C + G + Sbjct: 155 ACEFGRVGVV 164 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/117 (32%), Positives = 67/117 (57%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H+ A G+ E + L+ A D +D +G R LH+A G + +++L+AG+AV+ Sbjct: 51 SALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNV 110 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + PLH AA +G + ++LL+H + + + GKTP+++A + VV+LL Sbjct: 111 PSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCIVDNSGKTPLDLACEFGRVGVVQLL 167 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 8/125 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E +K L G+ + EG LH A +G +E+LL+ + +D Sbjct: 86 LHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCIVD 145 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVML--------QNLDGKTPIEVAKLNSQDEVV 199 + TPL A +GR V LLL L + +G +P+ +A N +++ Sbjct: 146 NSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDII 205 Query: 198 KLLEQ 184 +LL Q Sbjct: 206 RLLLQ 210 Score = 47.0 bits (110), Expect = 5e-05 Identities = 36/123 (29%), Positives = 54/123 (43%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAV---- 367 +H A G + + L +N D G+ L AC +G + ++LL + Sbjct: 119 LHLAAQHGHYDVSEMLLQHQSNPCIVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLE 178 Query: 366 ----DALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVV 199 D D N +PLH AA G + + LLL+ G + Q G T + A L + EVV Sbjct: 179 PRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVV 237 Query: 198 KLL 190 +LL Sbjct: 238 RLL 240
>ANKR5_MOUSE (Q9D2J7) Ankyrin repeat domain-containing protein 5| Length = 775 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/108 (35%), Positives = 61/108 (56%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD LKKA++ G D +D + L AC G + + L+E GA V+A D TPL Sbjct: 503 GDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPL 562 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 H+A G+++ V+LL+K GA++ +++ TP+ A + + + VK L Sbjct: 563 HFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYL 610 Score = 62.0 bits (149), Expect = 2e-09 Identities = 34/110 (30%), Positives = 60/110 (54%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G+ + +K ++ GAN + D LHFAC G+ E+L++AGA++DA N +TPL Sbjct: 536 GNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPL 595 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 A R + V LL GA ++N G +++AK + ++ ++++ Sbjct: 596 SRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKE 645 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/97 (29%), Positives = 46/97 (47%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E ++ L+ G + D + A HFA G ++L + + + NTPL Sbjct: 196 GVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPL 255 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 H+AA G +C + + G + +NL+ KTP VAK Sbjct: 256 HFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAK 292 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = -3 Query: 486 LDGGANKDEEDVE-GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 L+ GAN + + GR AL + G L+ +LE G V+A D +++ H+AA G Sbjct: 171 LEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGF 230 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + + LL + + L +DG TP+ A + + K + Q Sbjct: 231 FDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQ 272 Score = 37.4 bits (85), Expect = 0.042 Identities = 25/82 (30%), Positives = 37/82 (45%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 + F G+L + +E G VD D TPL A G + V L++ GA V + Sbjct: 496 ISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATD 555 Query: 255 LDGKTPIEVAKLNSQDEVVKLL 190 TP+ A Q ++V+LL Sbjct: 556 NFLWTPLHFACHAGQQDIVELL 577
>UACA_HUMAN (Q9BZF9) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1416 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/117 (34%), Positives = 57/117 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S+ H S G+ E L L G + D GR ALH A YG C + LL+ + Sbjct: 70 SVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 129 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D T LH AA + LL HGA+V +++DG+TP+ +A S+ + +LL Sbjct: 130 ADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLL 186 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 1/112 (0%) Frame = -3 Query: 522 ASVGDAEGLKKAL-DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNK 346 A GD E + L G N + DVEGR H G L+C +L G + D Sbjct: 42 AERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAG 101 Query: 345 NTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH AA YG C+ LL++ +L G+T + A + ++LL Sbjct: 102 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLL 153 Score = 46.2 bits (108), Expect = 9e-05 Identities = 31/100 (31%), Positives = 47/100 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G A L+K L + D++GR ALH A ++L + GA+V+A D Sbjct: 105 LHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 164 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 + TPL A R LL+ GA V ++ +T + Sbjct: 165 VDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTAL 204 Score = 36.2 bits (82), Expect = 0.094 Identities = 18/54 (33%), Positives = 28/54 (51%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 +D GA+ + D + R AL C YG E+L++ GA + LD + +YA Sbjct: 187 IDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYA 240
>CSKI1_MOUSE (Q6P9K8) Caskin-1 (CASK-interacting protein 1)| Length = 1431 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/130 (35%), Positives = 68/130 (52%), Gaps = 5/130 (3%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + +D +G ALH A G + +LLEA AAVD D PLHYAA GRKE + L Sbjct: 41 NVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKL 100 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID-----PKTL 127 +LK G+AV + + +G P+ +A + +V ++L Q S+P ++D P L Sbjct: 101 VLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQ------HQSNPCMVDNSGKTPLDL 154 Query: 126 PCFWSLSGAM 97 C + G + Sbjct: 155 ACEFGRVGVV 164 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/117 (32%), Positives = 67/117 (57%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H+ A G+ E + L+ A D +D +G R LH+A G + +++L+AG+AV+ Sbjct: 51 SALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNV 110 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + PLH AA +G + ++LL+H + + + GKTP+++A + VV+LL Sbjct: 111 PSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLL 167 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 8/125 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E +K L G+ + EG LH A +G +E+LL+ + +D Sbjct: 86 LHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVD 145 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVML--------QNLDGKTPIEVAKLNSQDEVV 199 + TPL A +GR V LLL L + +G +P+ +A N +++ Sbjct: 146 NSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDII 205 Query: 198 KLLEQ 184 +LL Q Sbjct: 206 RLLLQ 210 Score = 47.4 bits (111), Expect = 4e-05 Identities = 36/123 (29%), Positives = 54/123 (43%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAV---- 367 +H A G + + L +N D G+ L AC +G + ++LL + Sbjct: 119 LHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLE 178 Query: 366 ----DALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVV 199 D D N +PLH AA G + + LLL+ G + Q G T + A L + EVV Sbjct: 179 PRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVV 237 Query: 198 KLL 190 +LL Sbjct: 238 RLL 240
>PSD10_MOUSE (Q9Z2X2) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 231 Score = 67.8 bits (164), Expect = 3e-11 Identities = 40/104 (38%), Positives = 54/104 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H AS E L+GGAN D +D A+H A G LK ILL A+ + D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQD 169 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 NTPLH A R E L+ GA++ ++N + KTP++VAK Sbjct: 170 TEGNTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAK 213 Score = 62.4 bits (150), Expect = 1e-09 Identities = 41/117 (35%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = -3 Query: 537 IVHNTASVGDAEGLK-KALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 ++ N A G + LK + L + D + R ALH+AC G + E LL+ G V+ Sbjct: 9 MICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVND 68 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D +PLH AA GR E V LL GA V N +G TP+ A ++ E+ +L Sbjct: 69 KDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVML 125 Score = 60.1 bits (144), Expect = 6e-09 Identities = 40/117 (34%), Positives = 59/117 (50%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H AS G E +K L GA+ + + G LH+A + A +LLE GA DA Sbjct: 75 SPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D T +H AA G + V +LL + A+ +Q+ +G TP+ +A + E K L Sbjct: 135 KDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFL 191 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/87 (36%), Positives = 46/87 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H S G E ++ L G +++D G LH A G + + LL GA V+A++ Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVN 103 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGA 274 +N TPLHYAA R E +LL+ GA Sbjct: 104 QNGCTPLHYAASKNRHEIAVMLLEGGA 130 Score = 39.7 bits (91), Expect = 0.009 Identities = 22/72 (30%), Positives = 38/72 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G+ + + L A+ + +D EG LH AC ++ A+ L+ GA++ + Sbjct: 143 MHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGASIYIEN 202 Query: 354 KNKNTPLHYAAG 319 K + TPL A G Sbjct: 203 KEEKTPLQVAKG 214
>ASB13_MOUSE (Q8VBX0) Ankyrin repeat and SOCS box protein 13 (ASB-13)| Length = 278 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/115 (37%), Positives = 64/115 (55%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 VH A G++ L++ +D GA ++ V+ LH A G+ +C ++LL AGA VDA + Sbjct: 23 VHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARN 82 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + +TPL A G ECV LLL +GA V L +P+ A ++ E V+LL Sbjct: 83 IDGSTPLCDACASGSIECVKLLLSYGAKVN-PPLYTASPLHEACMSGSSECVRLL 136 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/101 (32%), Positives = 52/101 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H G +E ++ +D GAN + D LH AC L C ++LL AGA V+A Sbjct: 119 SPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNA 178 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTP 238 K T LH+AA + +++L++ G + ++ GK P Sbjct: 179 A-KLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKP 218 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/85 (40%), Positives = 49/85 (57%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVM 265 R +H A GE + L+++GA V+ + + TPLH A+ G+ +CV LLL GA V Sbjct: 20 RTPVHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVD 79 Query: 264 LQNLDGKTPIEVAKLNSQDEVVKLL 190 +N+DG TP+ A + E VKLL Sbjct: 80 ARNIDGSTPLCDACASGSIECVKLL 104 Score = 52.4 bits (124), Expect = 1e-06 Identities = 36/109 (33%), Positives = 51/109 (46%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E +K L GA K + LH AC G +C +L++ GA ++A D + TPL Sbjct: 96 GSIECVKLLLSYGA-KVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPL 154 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 H A +CV +LL GA V L AK+ + D + L+E Sbjct: 155 HVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIE 203 Score = 34.7 bits (78), Expect = 0.27 Identities = 19/53 (35%), Positives = 27/53 (50%) Frame = -3 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TP+H AA G + L+ GA V +D TP+ A L Q + V+LL Sbjct: 19 ERTPVHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLL 71
>LITD_LATMA (Q25338) Delta-latroinsectotoxin precursor (Delta-LIT)| Length = 1214 Score = 67.8 bits (164), Expect = 3e-11 Identities = 40/117 (34%), Positives = 63/117 (53%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H S G +K+ L G+N +E+ EG +LH A E + A +L+E GA ++A Sbjct: 743 TVLHLAVSTGQINIIKELLKRGSNIEEKTGEGYTSLHIAAMRKEPEIAVVLIENGADIEA 802 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPLH AA GRK V LL+ GA + + DG T + +A + + V+ L Sbjct: 803 RSADNLTPLHSAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLAVSGRKMKTVETL 859 Score = 43.5 bits (101), Expect = 6e-04 Identities = 23/70 (32%), Positives = 35/70 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H+ A +G + L+ GA+ + +G ALH A ++K E LL GA + D Sbjct: 811 LHSAAKIGRKSTVLYLLEKGADIGAKTADGSTALHLAVSGRKMKTVETLLNKGANLKEYD 870 Query: 354 KNKNTPLHYA 325 NK P+H A Sbjct: 871 NNKYLPIHKA 880 Score = 40.0 bits (92), Expect = 0.007 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 3/102 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYG 313 ++ GA+ + + R A+H G K A L ++D K+KN TPLH AA G Sbjct: 489 IEKGADIEAKFDNDRSAMHAVAYRGNNKIALRFLLKNQSIDIELKDKNGFTPLHIAAEAG 548 Query: 312 RKECVDLLLKHGAAVMLQ-NLDGKTPIEVAKLNSQDEVVKLL 190 + V LL+ HGA V + + TP+ +A + + V+ L Sbjct: 549 QAGFVKLLINHGADVNAKTSKTNLTPLHLATRSGFSKTVRNL 590 Score = 38.1 bits (87), Expect = 0.025 Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 4/109 (3%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEIL--LEAGAAVDALDKNKN-TPL 334 E + ++ A+ + +DV +HFA G +K L ++ +++++ +N N TPL Sbjct: 652 EVAESLVESNADLNIQDVNHMAPIHFAASMGSIKMLRYLISIKDKVSINSVTENNNWTPL 711 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGK-TPIEVAKLNSQDEVVKLL 190 H+A + +++ LLK + DG T + +A Q ++K L Sbjct: 712 HFAIYFKKEDAAKELLKQDDINLTIVADGNLTVLHLAVSTGQINIIKEL 760 Score = 36.2 bits (82), Expect = 0.094 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 4/101 (3%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 +K+ + G H A + AE L+E+ A ++ D N P+H+AA G + + Sbjct: 630 DKNAQSTSGLTPFHLAIINESQEVAESLVESNADLNIQDVNHMAPIHFAASMGSIKMLRY 689 Query: 291 LLKHGAAVMLQNL---DGKTPIEVA-KLNSQDEVVKLLEQD 181 L+ V + ++ + TP+ A +D +LL+QD Sbjct: 690 LISIKDKVSINSVTENNNWTPLHFAIYFKKEDAAKELLKQD 730
>PSD10_RAT (Q9Z2X3) 26S proteasome non-ATPase regulatory subunit 10 (26S| proteasome regulatory subunit p28) (Gankyrin) Length = 231 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/104 (38%), Positives = 55/104 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H AS E L+GGAN D ++ A+H A G LK ILL A+ + D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHILLFYKASTNIQD 169 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 NTPLH A R E LL+ GA++ ++N + KTP++VAK Sbjct: 170 TEGNTPLHLACDEERVEEAKLLVTQGASIYIENKEEKTPLQVAK 213 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/117 (35%), Positives = 60/117 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H AS G E +K L GA + + G ALH+A + A +LLE GA DA Sbjct: 75 SPLHIAASAGRDEIVKALLIKGAQVNAVNQNGCTALHYAASKNRHEIAVMLLEGGANPDA 134 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + T +H AA G + V +LL + A+ +Q+ +G TP+ +A + E KLL Sbjct: 135 KNHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191 Score = 60.1 bits (144), Expect = 6e-09 Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = -3 Query: 537 IVHNTASVGDAEGLKKALDGGAN-KDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +V N A G + LK+++ + D + R ALH+AC G + E LL+ G V+ Sbjct: 9 MVCNLAYNGKLDELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNE 68 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D +PLH AA GR E V LL GA V N +G T + A ++ E+ +L Sbjct: 69 KDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAVNQNGCTALHYAASKNRHEIAVML 125 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/115 (32%), Positives = 55/115 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H S G E ++ L G +E+D G LH A G + + LL GA V+A++ Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNEKDDAGWSPLHIAASAGRDEIVKALLIKGAQVNAVN 103 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N T LHYAA R E +LL+ GA +N T + A ++V +L Sbjct: 104 QNGCTALHYAASKNRHEIAVMLLEGGANPDAKNHYDATAMHRAAAKGNLKMVHIL 158 Score = 40.4 bits (93), Expect = 0.005 Identities = 22/72 (30%), Positives = 39/72 (54%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G+ + + L A+ + +D EG LH AC ++ A++L+ GA++ + Sbjct: 143 MHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKLLVTQGASIYIEN 202 Query: 354 KNKNTPLHYAAG 319 K + TPL A G Sbjct: 203 KEEKTPLQVAKG 214
>CSKI2_XENLA (Q6DD51) Caskin-2| Length = 1205 Score = 67.0 bits (162), Expect = 5e-11 Identities = 42/117 (35%), Positives = 65/117 (55%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H+ A G++E L L+ A+ D +D G R LH+A G+ + +LL A A+V+A Sbjct: 51 SALHHAALSGNSELLLLLLEMQASVDIKDGNGMRPLHYAAWQGQPEPVRLLLRASASVNA 110 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + PLH AA YG E + LL+H + N KTP+++A + +VV+LL Sbjct: 111 ASHDGQIPLHLAAQYGHYEVSETLLQHQSNPCHVNKGKKTPLDLACEFGRVKVVQLL 167 Score = 60.8 bits (146), Expect = 4e-09 Identities = 38/96 (39%), Positives = 52/96 (54%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + +D +G ALH A G + +LLE A+VD D N PLHYAA G+ E V L Sbjct: 41 NVNHQDADGFSALHHAALSGNSELLLLLLEMQASVDIKDGNGMRPLHYAAWQGQPEPVRL 100 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LL+ A+V + DG+ P+ +A EV + L Q Sbjct: 101 LLRASASVNAASHDGQIPLHLAAQYGHYEVSETLLQ 136 Score = 53.5 bits (127), Expect = 6e-07 Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E ++ L A+ + +G+ LH A YG + +E LL+ + ++ Sbjct: 86 LHYAAWQGQPEPVRLLLRASASVNAASHDGQIPLHLAAQYGHYEVSETLLQHQSNPCHVN 145 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGK--------TPIEVAKLNSQDEVV 199 K K TPL A +GR + V LLL V L K TP+ +A N EV+ Sbjct: 146 KGKKTPLDLACEFGRVKVVQLLLNSHLCVSLLEGTSKDPTDPNFTTPLHLAAKNGHLEVI 205 Query: 198 KLL 190 +LL Sbjct: 206 RLL 208 Score = 50.8 bits (120), Expect = 4e-06 Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEA-------- 379 +H A G E + L +N + + L AC +G +K ++LL + Sbjct: 119 LHLAAQYGHYEVSETLLQHQSNPCHVNKGKKTPLDLACEFGRVKVVQLLLNSHLCVSLLE 178 Query: 378 GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVV 199 G + D D N TPLH AA G E + LLLK G + G T + A L + EVV Sbjct: 179 GTSKDPTDPNFTTPLHLAAKNGHLEVIRLLLKLGIEINKVTKMG-TALHEAALCGKTEVV 237 Query: 198 KLL 190 KLL Sbjct: 238 KLL 240
>UACA_BOVIN (Q8HYY4) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein (Beta-actin-binding protein) (BetaCAP73) Length = 1401 Score = 67.0 bits (162), Expect = 5e-11 Identities = 40/117 (34%), Positives = 57/117 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S H AS G+ E L L G + D GR ALH A YG C + LL+ + Sbjct: 57 SAFHVVASKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 116 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +D T LH AA + LL HGA+V +++DG+TP+ +A + + +LL Sbjct: 117 VDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPTICQLL 173 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 1/112 (0%) Frame = -3 Query: 522 ASVGDAEGLKKAL-DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNK 346 A GD E + L G N + DVEGR A H G L+C +L G + D Sbjct: 29 AERGDVEKVSSILAKKGVNPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITTSDTAG 88 Query: 345 NTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH AA YG C+ LL++ +L G+T + A + ++LL Sbjct: 89 RNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLL 140 Score = 46.6 bits (109), Expect = 7e-05 Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 33/149 (22%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFA------------CGYGELKCA-- 397 +H A G A L+K L + D++GR ALH A C +G A Sbjct: 92 LHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 151 Query: 396 -------------------EILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 ++L++ GA +++ DK T L YG K+ V++L+K+GA Sbjct: 152 VDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCKDAVEVLIKNGA 211 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 V L + G A++ +++ LL+ Sbjct: 212 DVTLLDALGHDSSYYARIGDNLDILTLLK 240
>ASB13_HUMAN (Q8WXK3) Ankyrin repeat and SOCS box protein 13 (ASB-13)| Length = 278 Score = 66.6 bits (161), Expect = 6e-11 Identities = 42/115 (36%), Positives = 64/115 (55%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 VH A G++ L++ ++ GA ++ V+ LH A G+ +C ++LL AGA VDA + Sbjct: 23 VHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARN 82 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + +TPL A G ECV LLL +GA V L +P+ A ++ E V+LL Sbjct: 83 IDGSTPLCDACASGSIECVKLLLSYGAKVN-PPLYTASPLHEACMSGSSECVRLL 136 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/101 (32%), Positives = 52/101 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H G +E ++ +D GAN + D LH AC L C ++LL AGA V+A Sbjct: 119 SPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNA 178 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTP 238 K T LH+AA + +++L++ G + ++ GK P Sbjct: 179 A-KLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKP 218 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/85 (41%), Positives = 48/85 (56%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVM 265 R +H A GE + L+E+GA V+ + + TPLH A+ G+ CV LLL GA V Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVD 79 Query: 264 LQNLDGKTPIEVAKLNSQDEVVKLL 190 +N+DG TP+ A + E VKLL Sbjct: 80 ARNIDGSTPLCDACASGSIECVKLL 104 Score = 52.4 bits (124), Expect = 1e-06 Identities = 36/109 (33%), Positives = 51/109 (46%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E +K L GA K + LH AC G +C +L++ GA ++A D + TPL Sbjct: 96 GSIECVKLLLSYGA-KVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPL 154 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 H A +CV +LL GA V L AK+ + D + L+E Sbjct: 155 HVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIE 203 Score = 34.7 bits (78), Expect = 0.27 Identities = 19/53 (35%), Positives = 27/53 (50%) Frame = -3 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TP+H AA G + L++ GA V +D TP+ A L Q V+LL Sbjct: 19 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLL 71
>TNI3K_PONPY (Q5RF15) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) Length = 617 Score = 66.2 bits (160), Expect = 8e-11 Identities = 42/118 (35%), Positives = 60/118 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H +AE + L GGA+ + G ALH A G L+ A++LL+ GA V+ D Sbjct: 104 LHLAVYKDNAELITSLLHGGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQD 163 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 TPLH AA YG ++ LLLK GA V + G P+ +A + KLL ++ Sbjct: 164 AVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 221 Score = 47.0 bits (110), Expect = 5e-05 Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 2/120 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H G E L GAN + +D LH A YG + +LL+ GA V+ Sbjct: 137 LHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSG 196 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHG--AAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 + + PLH A+ G LL++ G A V Q+ + P+ ++VK L Q+ Sbjct: 197 EVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQN 256 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/86 (33%), Positives = 41/86 (47%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A + LL GA + + T LH A G E D+LL+HGA V Sbjct: 100 GFTALHLAVYKDNAELITSLLHGGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 159 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +Q+ TP+ +A ++V +LL Sbjct: 160 NIQDAVFFTPLHIAAYYGHEQVTRLL 185 Score = 32.3 bits (72), Expect = 1.4 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGE-LKCAEILLEAGAA-VDALDKNKNTPLHYAAGYG 313 + G + +E++ A H AC YG+ + + LL+ ++ ++ +T LH A +G Sbjct: 291 ISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHG 350 Query: 312 RKECVDLLLKHGAAVMLQNLD 250 V LL +GA + L D Sbjct: 351 HIHLVQFLLDNGADMNLVACD 371
>UACA_CANFA (Q9GL21) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein Length = 1415 Score = 66.2 bits (160), Expect = 8e-11 Identities = 40/117 (34%), Positives = 56/117 (47%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S H AS G+ E L L G + D GR ALH A YG C + LL+ + Sbjct: 72 SAFHVVASKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 131 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D T LH AA + LL HGA+V +++DG+TP+ +A + + +LL Sbjct: 132 ADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMCRPAICQLL 188 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 1/112 (0%) Frame = -3 Query: 522 ASVGDAEGLKKAL-DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNK 346 A GD E + L G N + DVEGR A H G L+C +L G + D Sbjct: 44 AERGDVEKVSSILAKKGINPGKLDVEGRSAFHVVASKGNLECLNAILIHGVDITTSDTAG 103 Query: 345 NTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH AA YG C+ LL++ +L G+T + A + ++LL Sbjct: 104 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLL 155 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/149 (26%), Positives = 63/149 (42%), Gaps = 33/149 (22%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFA------------CGYGELKCA-- 397 +H A G A L+K L + D++GR ALH A C +G A Sbjct: 107 LHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 166 Query: 396 -------------------EILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 ++L++ GA +++ DK T L YG K+ V++LLK+GA Sbjct: 167 VDGRTPLVLATQMCRPAICQLLIDRGAEINSRDKQNRTALMLGCEYGCKDAVEVLLKNGA 226 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 V L + G A++ +++ LL+ Sbjct: 227 DVSLLDALGHDSSYYARIGDNLDILTLLK 255
>GABP2_MOUSE (Q00420) GA-binding protein beta chain (GABP-beta-2 subunit)| (GABP-2) (GABP-beta-1 subunit) (GABPB-1) Length = 383 Score = 65.9 bits (159), Expect = 1e-10 Identities = 38/118 (32%), Positives = 61/118 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G + L G ++D R LH A G E+LL+ GA V+A Sbjct: 40 SPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHANIVEVLLKHGADVNA 99 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 D K T LH+A + +E V+LL+K+GA V Q+ KT +++ N +++ ++L+ Sbjct: 100 KDMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQ 157 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/86 (41%), Positives = 47/86 (54%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G LH A YG E+LL AG + DA K TPLH AA G V++LLKHGA V Sbjct: 38 GTSPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHANIVEVLLKHGADV 97 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +++ T + A ++ EVV+LL Sbjct: 98 NAKDMLKMTALHWATEHNHQEVVELL 123 Score = 32.7 bits (73), Expect = 1.0 Identities = 19/67 (28%), Positives = 32/67 (47%) Frame = -3 Query: 390 LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 +L A A D +PLH AA YG ++LL+ G + + +TP+ +A Sbjct: 24 ILMANGAPFTTDWLGTSPLHLAAQYGHFSTTEVLLRAGVSRDARTKVDRTPLHMAASEGH 83 Query: 210 DEVVKLL 190 +V++L Sbjct: 84 ANIVEVL 90
>GABP2_HUMAN (Q06547) GA-binding protein beta chain (GABP-beta-2 subunit)| (GABP-2) (GABP-beta-1 subunit) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2) Length = 395 Score = 65.9 bits (159), Expect = 1e-10 Identities = 38/118 (32%), Positives = 61/118 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G + L G ++D R LH A G E+LL+ GA V+A Sbjct: 40 SPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNA 99 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 D K T LH+A + +E V+LL+K+GA V Q+ KT +++ N +++ ++L+ Sbjct: 100 KDMLKMTALHWATEHNHQEVVELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQ 157 Score = 63.9 bits (154), Expect = 4e-10 Identities = 36/86 (41%), Positives = 47/86 (54%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G LH A YG E+LL AG + DA K TPLH AA G V++LLKHGA V Sbjct: 38 GTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADV 97 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +++ T + A ++ EVV+LL Sbjct: 98 NAKDMLKMTALHWATEHNHQEVVELL 123 Score = 33.1 bits (74), Expect = 0.80 Identities = 19/67 (28%), Positives = 32/67 (47%) Frame = -3 Query: 390 LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 +L A A D +PLH AA YG ++LL+ G + + +TP+ +A Sbjct: 24 ILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRAGVSRDARTKVDRTPLHMAASEGH 83 Query: 210 DEVVKLL 190 +V++L Sbjct: 84 ASIVEVL 90
>ANR50_HUMAN (Q9ULJ7) Ankyrin repeat domain-containing protein 50| Length = 1375 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/99 (36%), Positives = 54/99 (54%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ GAN + D EGR ALH +C G ++ ++L+ A V+A D K + L AA G Sbjct: 912 LENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHV 971 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + V LL++HGA V G T + +A +VV++L Sbjct: 972 KVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVL 1010 Score = 64.3 bits (155), Expect = 3e-10 Identities = 42/111 (37%), Positives = 55/111 (49%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 AS G A + +D GA D D +G L A G + ++LLE GA VD D N Sbjct: 669 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 728 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL AA G V+ LL GAAV + +G+T + +A EVV+ L Sbjct: 729 TPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTL 779 Score = 63.5 bits (153), Expect = 5e-10 Identities = 44/116 (37%), Positives = 59/116 (50%), Gaps = 5/116 (4%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFAC-----GYGELKCAEILLEAGAAVDAL 358 A +G E ++ LD GA + EDV+GR AL A G +L++ GA VD Sbjct: 631 AYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHC 690 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK+ TPL AA G + VDLLL+ GA V + +G+TP+ A VV L Sbjct: 691 DKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTL 746 Score = 59.7 bits (143), Expect = 8e-09 Identities = 32/117 (27%), Positives = 60/117 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++ ++ G+ E ++ LD G +++ D G LH A G E L+E GA + Sbjct: 762 TVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNE 821 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +D + P A+ G +CV +LL++ + + + DG+ + VA L ++V+LL Sbjct: 822 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELL 878 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/98 (36%), Positives = 47/98 (47%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E + L G D D + R AL A G LL+ GA V+ D T L Sbjct: 568 GHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTAL 627 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKL 220 AA G +E V+ LL HGA V +++DG+T + VA L Sbjct: 628 IAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAAL 665 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/96 (35%), Positives = 47/96 (48%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GAN + D +G AL A G + LL AG VD D + T L AA G ++ V Sbjct: 547 GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIV 606 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LL+HGA V + +G+T + A E+V+ L Sbjct: 607 LNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHL 642 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/108 (29%), Positives = 51/108 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G + ++ GA +E D +GR A G C +ILLE + +D Sbjct: 797 LHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRG 856 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 + L AA G ++ V+LL HGA V ++ DG+ + + L +Q Sbjct: 857 YDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQ 904 Score = 51.2 bits (121), Expect = 3e-06 Identities = 35/111 (31%), Positives = 51/111 (45%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 AS+G A + L GA D D EGR L A G ++ LL+ G + D Sbjct: 735 ASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGW 794 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPLH AA G + + L++ GA + DG+ P +A + V++L Sbjct: 795 TPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQIL 845 Score = 49.7 bits (117), Expect = 8e-06 Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 1/111 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + + L+GGA+ D D GR L A G LL GAAVD++D T L Sbjct: 705 GHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVL 764 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQ 184 A+ G E V LL G ++ G TP+ +A + + L+EQ Sbjct: 765 SIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQ 815 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/67 (35%), Positives = 37/67 (55%) Frame = -3 Query: 390 LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 LL+ GA+V+ D N T L AA G + V+LL+ GA + +++ G TP+ +A Sbjct: 477 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGH 536 Query: 210 DEVVKLL 190 +VV L Sbjct: 537 TKVVNCL 543 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/104 (28%), Positives = 51/104 (49%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S + + A G + ++ ++ GA D +G AL A G + ++LLE GA + Sbjct: 960 SALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNH 1019 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEV 229 D+ T + AA G + + LL K+GA+ +L+G +P V Sbjct: 1020 ADQFGRTAMRVAAKNGHSQIIKLLEKYGAS----SLNGCSPSPV 1059
>ANS4B_MOUSE (Q8K3X6) Ankyrin repeat and SAM domain-containing protein 4B| (Harmonin-interacting ankyrin repeat-containing protein) (Harp) Length = 423 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/116 (35%), Positives = 55/116 (47%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 H AS E LK+A N +ED G A +G L+ EI+ G D D Sbjct: 6 HQAASDSYLELLKEATKRDLNLSDED--GMTPTLLAAYHGNLEALEIICSRGGDPDKCDI 63 Query: 351 NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 NTPLHYAA G C+ L+ GA + + D K+P++ A Q E V LL++ Sbjct: 64 WGNTPLHYAASNGHTHCISFLVNFGANIFALDNDLKSPLDAAASREQKECVALLDK 119 Score = 54.7 bits (130), Expect = 3e-07 Identities = 36/101 (35%), Positives = 49/101 (48%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G+ E L+ G + D+ D+ G LH+A G C L+ GA + ALD + +PL Sbjct: 43 GNLEALEIICSRGGDPDKCDIWGNTPLHYAASNGHTHCISFLVNFGANIFALDNDLKSPL 102 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 AA +KECV LL K A +QN P V +L Q Sbjct: 103 DAAASREQKECVALLDK---AATVQNT--MNPKRVTRLKEQ 138
>UACA_MOUSE (Q8CGB3) Uveal autoantigen with coiled-coil domains and ankyrin| repeats protein (Nucling) (Nuclear membrane-binding protein) Length = 1411 Score = 65.5 bits (158), Expect = 1e-10 Identities = 39/117 (33%), Positives = 56/117 (47%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S H AS G+ E L L G + D GR ALH A YG C + LL+ + Sbjct: 72 SAFHVVASKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEH 131 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +D T LH A + LL HGA+V +++DG+TP+ +A + + +LL Sbjct: 132 VDLQGRTALHDAVMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLL 188 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 1/112 (0%) Frame = -3 Query: 522 ASVGDAEGLKKAL-DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNK 346 A GD E + L G + + DVEGR A H G L+C +L G V D Sbjct: 44 AERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILTHGIDVATRDSAG 103 Query: 345 NTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH AA YG C+ LL++ +L G+T + A + ++LL Sbjct: 104 RNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAVMADCPSSIQLL 155 Score = 34.7 bits (78), Expect = 0.27 Identities = 18/54 (33%), Positives = 28/54 (51%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 +D GA+ + D + R AL C YG E+L++ GA + LD + +YA Sbjct: 189 IDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVKNGADLTLLDALGHDSSYYA 242
>BARD1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 768 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/103 (33%), Positives = 57/103 (55%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H + GD ++ L G + + +D G LH AC +G LK E+LL+ A V+ Sbjct: 420 TLLHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKIVELLLQHNALVNT 479 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE 232 + ++PLH AA G + V +LL HGA+ N+ G+ P++ Sbjct: 480 TGYHNDSPLHDAAKNGHIDIVKVLLSHGASRNAVNIFGERPVD 522 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/99 (31%), Positives = 46/99 (46%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L G + + G LH A G++ E LL+ G + D TPLH A +G Sbjct: 405 LSSGIPARKRNHRGETLLHIASIKGDISSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHL 464 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + V+LLL+H A V +P+ A N ++VK+L Sbjct: 465 KIVELLLQHNALVNTTGYHNDSPLHDAAKNGHIDIVKVL 503
>INVS_CHICK (Q8UVC3) Inversin| Length = 1106 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGAN-KDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 S VH A GD L K + G + KD+ED GR L + + CAE LL+AGA V+ Sbjct: 16 SEVHAAAVNGDKSTLLKLIAGNSELKDKEDQFGRTPLMYCVLADRVDCAEALLKAGADVN 75 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D+++ T LH AA G + LLL M ++L+G TP+ + + + + LL Sbjct: 76 RADRSRRTALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALL 133 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 2/114 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--AGAAVDA 361 +H A G+ +K L N ++D+EG LH + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLKHMAPGEVDT 144 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVV 199 D+NK T LH++A Y E V LL+KH + + + +++GK P+ A N + Sbjct: 145 QDRNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWAANNKDPSAI 198 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/83 (42%), Positives = 47/83 (56%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 ALH A G + ++LLE A VDALD K+TPL A G KE + L+K GA V L Sbjct: 360 ALHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLV 419 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + DG +P+ A L +V ++L Sbjct: 420 DQDGHSPLHWAALGGNADVCQIL 442 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/103 (30%), Positives = 54/103 (52%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G +K L+ A D DV L AC G + + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLVD 420 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 ++ ++PLH+AA G + +L+++ +Q+ G+TP++ A Sbjct: 421 QDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/109 (30%), Positives = 53/109 (48%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G E ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA G C+ +LL++ A +Q+ +G+T + N + +KLL Sbjct: 460 LQCAAYGGYINCMVVLLENNADPNIQDKEGRTALHWLCNNGYLDAIKLL 508 Score = 48.1 bits (113), Expect = 2e-05 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G+A+ + ++ N + +D GR L A G + C +LLE A + Sbjct: 425 SPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMVVLLENNADPNI 484 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAV--MLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK T LH+ G + + LLL A M + + TP++ A L EV++ + Sbjct: 485 QDKEGRTALHWLCNNGYLDAIKLLLGFDAFPNHMENSEERYTPLDYALLGEHHEVIQFM 543 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 2/91 (2%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLE-AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLK 283 +D EGR LHFA G + ++L G V + D TPLH+AA G + V LLL+ Sbjct: 217 QDYEGRTPLHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLE 276 Query: 282 HGA-AVMLQNLDGKTPIEVAKLNSQDEVVKL 193 + + G TP+ A ++ E V++ Sbjct: 277 RNKFGTIPSDSQGATPLHYAAQSNFAETVEV 307 Score = 45.1 bits (105), Expect = 2e-04 Identities = 36/117 (30%), Positives = 53/117 (45%), Gaps = 2/117 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA-- 361 +H A AE ++ L + KD+ D+EGR + +A G G +L+ +D Sbjct: 293 LHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDLKLDIDINM 352 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK T LH AA G V LLL+ A V ++ TP+ A EV++ L Sbjct: 353 TDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTL 409 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYG 313 L+ A+ + +D EGR ALH+ C G L ++LL A + ++ ++ TPL YA Sbjct: 476 LENNADPNIQDKEGRTALHWLCNNGYLDAIKLLLGFDAFPNHMENSEERYTPLDYALLGE 535 Query: 312 RKECVDLLLKHGA 274 E + +L+HGA Sbjct: 536 HHEVIQFMLEHGA 548 Score = 42.7 bits (99), Expect = 0.001 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 1/97 (1%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGA-AVDALDKNKNTPLHYAAGYGRKEC 301 G N D R LH+A G + +LLE D TPLHYAA E Sbjct: 245 GCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIPSDSQGATPLHYAAQSNFAET 304 Query: 300 VDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V++ LKH + +L+G+T A D V++ + Sbjct: 305 VEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTM 341 Score = 30.0 bits (66), Expect = 6.7 Identities = 23/91 (25%), Positives = 37/91 (40%), Gaps = 2/91 (2%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLL--LK 283 D +G LH+A + E+ L+ + D D T +AAG G + + LK Sbjct: 286 DSQGATPLHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDLK 345 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + + T + A L+ VKLL Sbjct: 346 LDIDINMTDKYAGTALHAAALSGHVSTVKLL 376
>HECD1_HUMAN (Q9ULT8) E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing| protein 1) (E3 ligase for inhibin receptor) (EULIR) Length = 2612 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/109 (36%), Positives = 63/109 (57%), Gaps = 1/109 (0%) Frame = -3 Query: 510 DAEGLKKALDGGANK-DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 D + L A+D GA + + D G+ L++A +G + E L E GA V+ +++ L Sbjct: 374 DTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNR--GQRSSSL 431 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 HYAA +GR + LL+HGA L++ DGKTP++ A+ EVV +L+ Sbjct: 432 HYAACFGRPQVAKTLLRHGANPDLRDEDGKTPLDKARERGHSEVVAILQ 480 Score = 35.4 bits (80), Expect = 0.16 Identities = 20/54 (37%), Positives = 28/54 (51%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 +LH+A +G + A+ LL GA D D++ TPL A G E V +L G Sbjct: 430 SLHYAACFGRPQVAKTLLRHGANPDLRDEDGKTPLDKARERGHSEVVAILQSPG 483
>ANS4B_HUMAN (Q8N8V4) Ankyrin repeat and SAM domain-containing protein 4B| (Harmonin-interacting ankyrin repeat-containing protein) (Harp) Length = 460 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/116 (35%), Positives = 56/116 (48%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 H AS E LK+A N +ED G A +G L+ EI+ G D D Sbjct: 6 HQAASDSYLELLKEATKRDLNLSDED--GMTPTLLAAYHGNLEALEIICSRGGDPDRCDI 63 Query: 351 NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 NTPLH+AA G CV L+ GA + + D +TP++ A Q+E V LL++ Sbjct: 64 WGNTPLHFAASNGHAHCVSFLVNFGANIFALDNDLQTPLDAAASREQNECVALLDK 119 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/101 (35%), Positives = 47/101 (46%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G+ E L+ G + D D+ G LHFA G C L+ GA + ALD + TPL Sbjct: 43 GNLEALEIICSRGGDPDRCDIWGNTPLHFAASNGHAHCVSFLVNFGANIFALDNDLQTPL 102 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 AA + ECV LL K A + N P +V +L Q Sbjct: 103 DAAASREQNECVALLDKAATAQNIMN-----PKKVTRLKEQ 138
>BARD1_HUMAN (Q99728) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 777 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/120 (30%), Positives = 63/120 (52%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H + GD ++ L G++ + +D G LH AC +G LK E+LL+ A V+ Sbjct: 430 TLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNT 489 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 ++PLH AA G + V LLL +GA+ N+ G P++ S ++ L E++ Sbjct: 490 TGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKN 549 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/86 (34%), Positives = 43/86 (50%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G LH A G++ E LL+ G+ + D TPLH A +G + V+LLL+H A V Sbjct: 428 GETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALV 487 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +P+ A N ++VKLL Sbjct: 488 NTTGYQNDSPLHDAAKNGHVDIVKLL 513
>INVS_CANFA (Q6JAN1) Inversin (Inversion of embryo turning protein)| (Nephrocystin-2) Length = 1081 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/105 (36%), Positives = 57/105 (54%), Gaps = 2/105 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--AGAAVDA 361 +H A G+ +K L AN ++D+E LH A + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLATRHKSPKCLALLLKFMAPGEVDT 144 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 DKNK T LH++A Y E V LL+KH + + + +++GK P+ A Sbjct: 145 QDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWA 189 Score = 62.4 bits (150), Expect = 1e-09 Identities = 43/118 (36%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGG-ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 S VH A GD L + + G A KD+ED GR L + L CA+ LL+AGA V+ Sbjct: 16 SQVHAAAINGDKGALHRLIIGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVN 75 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D ++ T LH AA G + LLL A M ++L+ TP+ +A + + + LL Sbjct: 76 KTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLATRHKSPKCLALL 133 Score = 56.2 bits (134), Expect = 9e-08 Identities = 34/89 (38%), Positives = 47/89 (52%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A G + ++LLE A VDA D K+TPL A G K+ + L+K G Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A V L + DG + + A L +V ++L Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQIL 442 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++H A G+A+ + ++ N + +D GR L A G + C +L+E A + Sbjct: 425 SLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNI 484 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGA--AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK T LH++ G + + LLL A M N + TP++ A L + EV++ + Sbjct: 485 QDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/103 (29%), Positives = 52/103 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G +K L+ A D DV L AC G + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVD 420 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 ++ ++ LH+AA G + +L+++ +Q+ G+TP++ A Sbjct: 421 QDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 50.4 bits (119), Expect = 5e-06 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 2/73 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYG 313 ++ A+ + +D EGR ALH++C G L ++LL+ A + ++ N+ TPL YA Sbjct: 476 MENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGE 535 Query: 312 RKECVDLLLKHGA 274 R E + +L+HGA Sbjct: 536 RHEVIQFMLEHGA 548 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/109 (28%), Positives = 54/109 (49%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G + ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA G C+ +L+++ A +Q+ +G+T + + N + +KLL Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VD 364 S VH + DA + L+ +D EGR LHFA G + ++L + + Sbjct: 196 SAVHTVRCILDAAPTESLLNW------QDYEGRTPLHFAVADGNVTVVDVLTSYESCNIT 249 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLL-KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 + D TPLH+AA G + V LLL ++ + + + G TP+ A ++ E VK+ Sbjct: 250 SYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAG-AAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 R LH+A G + +LLE + D TPLHYAA E V + LKH + Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVK 315 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +L+G+T A D+V++ + Sbjct: 316 DDSDLEGRTSFMWAAGKGSDDVLRTM 341 Score = 38.5 bits (88), Expect = 0.019 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE---LKCAEILLEAGAAVD 364 +H +A + E +K + +N DVEG+ LH+A + + + +L+A Sbjct: 153 LHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTES 212 Query: 363 AL---DKNKNTPLHYAAGYGRKECVDLLLKHGAA--VMLQNLDGKTPIEVAKLNSQDEVV 199 L D TPLH+A G VD+L + + NL +TP+ A L ++V Sbjct: 213 LLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNL-FRTPLHWAALLGHAQIV 271 Query: 198 KLL 190 LL Sbjct: 272 HLL 274 Score = 32.0 bits (71), Expect = 1.8 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD--LLLK 283 D +G LH+A + ++ L+ + D D T +AAG G + + L LK Sbjct: 286 DSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLK 345 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + + G T + A L+ VKLL Sbjct: 346 SDIDINMADKYGGTALHAAALSGHVSTVKLL 376
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 63.9 bits (154), Expect = 4e-10 Identities = 41/118 (34%), Positives = 59/118 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H +AE + L GA+ + G ALH A G L+ A++LL+ GA V+ D Sbjct: 206 LHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQD 265 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 TPLH AA YG ++ LLLK GA V + G P+ +A + KLL ++ Sbjct: 266 AVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEE 323 Score = 47.4 bits (111), Expect = 4e-05 Identities = 29/86 (33%), Positives = 42/86 (48%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A + LL +GA + + T LH A G E D+LL+HGA V Sbjct: 202 GFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANV 261 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +Q+ TP+ +A ++V +LL Sbjct: 262 NIQDAVFFTPLHIAAYYGHEQVTRLL 287 Score = 46.6 bits (109), Expect = 7e-05 Identities = 34/119 (28%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H G E L GAN + +D LH A YG + +LL+ GA V+ Sbjct: 239 LHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSG 298 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHG--AAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + + PLH A+ G LL++ G A V Q+ + P+ ++VK L Q Sbjct: 299 EVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQ 357 Score = 32.3 bits (72), Expect = 1.4 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGE-LKCAEILLEAGAA-VDALDKNKNTPLHYAAGYG 313 + G + +E++ A H AC YG+ + + LL+ ++ ++ +T LH A +G Sbjct: 393 ISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHG 452 Query: 312 RKECVDLLLKHGAAVMLQNLD 250 V LL +GA + L D Sbjct: 453 HIRLVQFLLDNGADMNLVACD 473
>ANKR2_HUMAN (Q9GZV1) Ankyrin repeat domain-containing protein 2 (Skeletal| muscle ankyrin repeat protein) (hArpp) Length = 333 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/115 (33%), Positives = 61/115 (53%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G E L+K LD GA D +D A+H+AC G L+ ++L GA + D Sbjct: 158 LHRASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRD 217 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K +TPLH A G+ E V+ L G + ++ +G T + A ++ +++KLL Sbjct: 218 KLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKIIKLL 272 Score = 56.6 bits (135), Expect = 7e-08 Identities = 38/106 (35%), Positives = 54/106 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + ++K L G + D D R ALH A G ++ E LL+ GA VD D+ T + Sbjct: 132 GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAM 191 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 H+A G E V LL HGA +++ TP+ VA Q E+V+ Sbjct: 192 HWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVE 237 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/76 (35%), Positives = 39/76 (51%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++K E L G + D D+ + T LH A+ G E ++ LL +GA V Q+ T + Sbjct: 132 GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDRLDCTAM 191 Query: 234 EVAKLNSQDEVVKLLE 187 A EVVKLL+ Sbjct: 192 HWACRGGHLEVVKLLQ 207
>AKIB1_HUMAN (Q9P2G1) Ankyrin repeat and IBR domain-containing protein 1| (Fragment) Length = 1214 Score = 63.9 bits (154), Expect = 4e-10 Identities = 33/68 (48%), Positives = 44/68 (64%), Gaps = 1/68 (1%) Frame = -3 Query: 375 AAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQDEVV 199 AA+DA+D KNTPLHYAA G K CV+LL+KHG + +N + TP + A K + +D + Sbjct: 261 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLAL 320 Query: 198 KLLEQDVF 175 L Q VF Sbjct: 321 NLESQMVF 328 Score = 32.0 bits (71), Expect = 1.8 Identities = 17/54 (31%), Positives = 27/54 (50%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKE 304 D D + LH+A G C E+L++ G + A ++NK+TP A K+ Sbjct: 264 DAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKD 317
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/117 (32%), Positives = 60/117 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G +K GA D + R LH A G+++ + LL++GA DALD Sbjct: 498 LHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALD 557 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 ++ PLH AA G+ +LL++GA++ L G TP+ +A E++ LL + Sbjct: 558 QSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAE 614 Score = 60.1 bits (144), Expect = 6e-09 Identities = 37/96 (38%), Positives = 50/96 (52%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + D +G LHFA G+ A +LL+ GA VDA ++ TPLH AA + Sbjct: 418 GADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVA 477 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LL+ A L +GKTP+ VA +VKLL Sbjct: 478 RLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513 Score = 53.9 bits (128), Expect = 4e-07 Identities = 29/95 (30%), Positives = 46/95 (48%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + + EG+ LH A +G + ++L GA +DA +N TPLH A G+ + Sbjct: 485 ADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQ 544 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LLK GA + G P+ A + + K+L Sbjct: 545 HLLKSGAVPDALDQSGYGPLHTAAARGKYLICKML 579 Score = 52.8 bits (125), Expect = 1e-06 Identities = 39/130 (30%), Positives = 60/130 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G E ++ L + D + G L A + +LL GA + +D Sbjct: 366 LHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD 425 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 ++ PLH+AA G LLL HGA V Q +G TP+ +A N+ + V +LL Sbjct: 426 EDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLV---- 481 Query: 174 L*SKPSDPVL 145 S+ +DP L Sbjct: 482 --SRQADPNL 489 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/103 (32%), Positives = 47/103 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A GD + LD GA D ++ EG LH A A +L+ A + + Sbjct: 432 LHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHE 491 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 TPLH AA +G V LL GA + Q + +TP+ +A Sbjct: 492 AEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLA 534 Score = 48.9 bits (115), Expect = 1e-05 Identities = 39/117 (33%), Positives = 54/117 (46%), Gaps = 1/117 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G K L GA+ + +G LH A G L+ +L E+ A + AL Sbjct: 564 LHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALG 623 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD-EVVKLLE 187 TPLH AA +G + V LL+ GA G TP+ +A S V+ LLE Sbjct: 624 AVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLE 680 Score = 48.5 bits (114), Expect = 2e-05 Identities = 34/117 (29%), Positives = 51/117 (43%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H G ++ L GA D D G LH A G+ ++LL GA+++ Sbjct: 531 LHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPT 590 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 TPLH AA G E + LL + A + TP+ +A + ++ VV L Q Sbjct: 591 HQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQ 647 Score = 47.0 bits (110), Expect = 5e-05 Identities = 35/115 (30%), Positives = 50/115 (43%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E + + AN LH A +GE LL+ GA +A + Sbjct: 597 LHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAE 656 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ TPLH A V LL+H A V +N G TP +A L ++K+L Sbjct: 657 QSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVL 711 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/116 (27%), Positives = 53/116 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G+ + L GA+ + + G LH A LLE A V A + Sbjct: 630 LHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARN 689 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 K TP H AA G + +L++ GA + +Q+ TP+++A + + ++ LE Sbjct: 690 KVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLE 745 Score = 40.4 bits (93), Expect = 0.005 Identities = 22/55 (40%), Positives = 29/55 (52%) Frame = -3 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +NK TPLH+ G E V LLL H V Q G TP+ +A + Q ++ LL Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALL 414
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/105 (36%), Positives = 57/105 (54%), Gaps = 1/105 (0%) Frame = -3 Query: 501 GLKKALDG-GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 GL K L G GA D + R LH A G+++ + LL+ GA DALD + +PLH A Sbjct: 516 GLVKLLSGQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKCGALPDALDHSGYSPLHIA 575 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A G+ +LL++GA++ L+ G TP+ +A E++ L Sbjct: 576 AARGKDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQL 620 Score = 56.6 bits (135), Expect = 7e-08 Identities = 30/95 (31%), Positives = 48/95 (50%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + EG+ LH A +G + ++L GA +DA +N TPLH A G+ + Sbjct: 493 ADLSPHEAEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQRNLRTPLHLAVERGKVRAIQ 552 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LLK GA + G +P+ +A +D + K+L Sbjct: 553 HLLKCGALPDALDHSGYSPLHIAAARGKDLIFKML 587 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/96 (36%), Positives = 49/96 (51%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + D +G LHFA G+ A +LL+ GA V+A + TPLH AA + Sbjct: 426 GADTNLADEDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVA 485 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LL+ A + +GKTP+ VA +VKLL Sbjct: 486 RLLVSRQADLSPHEAEGKTPLHVAAYFGHIGLVKLL 521 Score = 50.4 bits (119), Expect = 5e-06 Identities = 34/115 (29%), Positives = 53/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G E ++ L + D + G L A + +LL GA + D Sbjct: 374 LHFLVAGGSLEQVRLLLSHDVDVDCQTASGYTPLLIATQDQQPDLCALLLAHGADTNLAD 433 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ PLH+AA G LLL HGA V + +G TP+ +A N+ + V +LL Sbjct: 434 EDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVARLL 488 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/103 (31%), Positives = 46/103 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A GD + LD GA + + EG LH A A +L+ A + + Sbjct: 440 LHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVARLLVSRQADLSPHE 499 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 TPLH AA +G V LL GA + Q + +TP+ +A Sbjct: 500 AEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQRNLRTPLHLA 542 Score = 42.7 bits (99), Expect = 0.001 Identities = 28/82 (34%), Positives = 41/82 (50%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A GE LL+ GA +A +++ TPLH A G + LL++GA + N Sbjct: 638 LHLAAFQGEEGVMLALLQCGANPNAAEQSGWTPLHLAVHKGTFLGITHLLEYGADIHACN 697 Query: 255 LDGKTPIEVAKLNSQDEVVKLL 190 G TP +A L ++K+L Sbjct: 698 KVGWTPAHLAALKGNTAILKVL 719 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/103 (31%), Positives = 47/103 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G+ + L GAN + + G LH A G LLE GA + A + Sbjct: 638 LHLAAFQGEEGVMLALLQCGANPNAAEQSGWTPLHLAVHKGTFLGITHLLEYGADIHACN 697 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 K TP H AA G + +L+K A V ++ TP+++A Sbjct: 698 KVGWTPAHLAALKGNTAILKVLVKAAAQVDVKGGVSCTPLQLA 740 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/105 (31%), Positives = 48/105 (45%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A+ G K L GA+ + +G LH A G L+ L ++ +DA Sbjct: 570 SPLHIAAARGKDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQLAKSHVDLDA 629 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 L + TPLH AA G + + LL+ GA G TP+ +A Sbjct: 630 LGSMQWTPLHLAAFQGEEGVMLALLQCGANPNAAEQSGWTPLHLA 674 Score = 40.8 bits (94), Expect = 0.004 Identities = 34/136 (25%), Positives = 53/136 (38%) Frame = -3 Query: 591 VLSGPQXXXXXXXXXXESIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYG 412 +LSG + +H G ++ L GA D D G LH A G Sbjct: 520 LLSGQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKCGALPDALDHSGYSPLHIAAARG 579 Query: 411 ELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE 232 + ++LL GA+++ + TPLH A G E + L K + TP+ Sbjct: 580 KDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQLAKSHVDLDALGSMQWTPLH 639 Query: 231 VAKLNSQDEVVKLLEQ 184 +A ++ V+ L Q Sbjct: 640 LAAFQGEEGVMLALLQ 655 Score = 39.3 bits (90), Expect = 0.011 Identities = 21/55 (38%), Positives = 29/55 (52%) Frame = -3 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N+ TPLH+ G E V LLL H V Q G TP+ +A + Q ++ LL Sbjct: 368 ENRVTPLHFLVAGGSLEQVRLLLSHDVDVDCQTASGYTPLLIATQDQQPDLCALL 422
>AKIB1_MOUSE (Q6ZPS6) Ankyrin repeat and IBR domain-containing protein 1| (Fragment) Length = 1087 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/68 (48%), Positives = 43/68 (63%), Gaps = 1/68 (1%) Frame = -3 Query: 375 AAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQDEVV 199 AA+DA+D KNTPLHYAA G K CV+LL+KHG + +N + TP + A K +D + Sbjct: 139 AAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENRDTPCDCAEKQQHKDLAL 198 Query: 198 KLLEQDVF 175 L Q VF Sbjct: 199 SLESQMVF 206 Score = 30.8 bits (68), Expect = 4.0 Identities = 16/54 (29%), Positives = 27/54 (50%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKE 304 D D + LH+A G C E+L++ G + A ++N++TP A K+ Sbjct: 142 DAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENRDTPCDCAEKQQHKD 195
>CTTB2_OTOGA (Q2QLG9) Cortactin-binding protein 2 (CortBP2)| Length = 1655 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/87 (41%), Positives = 49/87 (56%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G AL+ A G C +LL A A V+A DKN TPL AA G ECV+LL+ + A Sbjct: 734 DGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDAH 793 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + +G+TP+ +A N E +KLL Sbjct: 794 INHAADEGQTPLYLACKNGNKECIKLL 820 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/117 (28%), Positives = 54/117 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +++ A G + ++ L+ A + D G L A G +C E+L+ A ++ Sbjct: 737 SALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDAHINH 796 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A G KEC+ LLL+ G ++ DG TP+ + +KLL Sbjct: 797 AADEGQTPLYLACKNGNKECIKLLLEAGTNRNVKTRDGWTPVHAVVDTGDVDSLKLL 853 Score = 41.6 bits (96), Expect = 0.002 Identities = 22/71 (30%), Positives = 37/71 (52%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 EG+ L+ AC G +C ++LLEAG + ++ TP+H G + + LL+ H A Sbjct: 800 EGQTPLYLACKNGNKECIKLLLEAGTNRNVKTRDGWTPVHAVVDTGDVDSLKLLMYHRAP 859 Query: 270 VMLQNLDGKTP 238 +L+ + P Sbjct: 860 ARGNSLNEEEP 870 Score = 33.9 bits (76), Expect = 0.47 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 L A G + +LL E G ++ ++ ++ L+ AA G +CV LLL A V Sbjct: 705 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAA 764 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + +G TP+ A E V+LL Sbjct: 765 DKNGFTPLCAAAAQGHFECVELL 787
>Y1425_THEVO (Q978J0) Hypothetical ANK-repeat protein TV1425| Length = 189 Score = 63.2 bits (152), Expect = 7e-10 Identities = 38/109 (34%), Positives = 60/109 (55%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G + K ++ +++D+EG AL +A L AE LL G+ V+ D + TP Sbjct: 42 LGMENAIDKLVENFDKLEDKDIEGSTALIWAVKNNRLGIAEKLLSKGSNVNTKDFSGKTP 101 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L ++ +G E LL+HGA V +NL+G+TP+ VA + E+VK L Sbjct: 102 LMWSIIFGYSEMSYFLLEHGANVNDRNLEGETPLIVASKYGRSEIVKKL 150 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/104 (32%), Positives = 57/104 (54%) Frame = -3 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 +K L G+N + +D G+ L ++ +G + + LLE GA V+ + TPL A+ Y Sbjct: 82 EKLLSKGSNVNTKDFSGKTPLMWSIIFGYSEMSYFLLEHGANVNDRNLEGETPLIVASKY 141 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 GR E V LL+ GA + ++L G T A++ + EV+K+ + Sbjct: 142 GRSEIVKKLLELGADISARDLTGLTAEASARIFGRQEVIKIFTE 185
>INVS_HUMAN (Q9Y283) Inversin (Inversion of embryo turning homolog)| (Nephrocystin-2) Length = 1065 Score = 62.8 bits (151), Expect = 9e-10 Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 2/105 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--AGAAVDA 361 +H A G+ +K L AN ++D+E LH + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDT 144 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 DKNK T LH++A Y E V LL+KH + + + +++GK P+ A Sbjct: 145 QDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWA 189 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGG-ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 S VH A GD L++ + G A KD+ED GR L + L CA+ LL+AGA V+ Sbjct: 16 SQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVN 75 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D ++ T LH AA G + LLL A M ++L+ TP+ + + + + LL Sbjct: 76 KTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALL 133 Score = 56.2 bits (134), Expect = 9e-08 Identities = 34/89 (38%), Positives = 47/89 (52%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A G + ++LLE A VDA D K+TPL A G K+ + L+K G Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGG 413 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A V L + DG + + A L +V ++L Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQIL 442 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++H A G+A+ + ++ N + +D GR L A G + C +L+E A + Sbjct: 425 SLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNI 484 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGA--AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK T LH++ G + + LLL A M N + TP++ A L + EV++ + Sbjct: 485 QDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/103 (29%), Positives = 52/103 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G +K L+ A D DV L AC G + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVD 420 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 ++ ++ LH+AA G + +L+++ +Q+ G+TP++ A Sbjct: 421 QDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 50.4 bits (119), Expect = 5e-06 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 2/73 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYG 313 ++ A+ + +D EGR ALH++C G L ++LL+ A + ++ N+ TPL YA Sbjct: 476 MENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGE 535 Query: 312 RKECVDLLLKHGA 274 R E + +L+HGA Sbjct: 536 RHEVIQFMLEHGA 548 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/109 (28%), Positives = 54/109 (49%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G + ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA G C+ +L+++ A +Q+ +G+T + + N + +KLL Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VD 364 S VH + DA + L+ +D EGR LHFA G + ++L + + Sbjct: 196 SAVHTVRCILDAAPTESLLNW------QDYEGRTPLHFAVADGNVTVVDVLTSYESCNIT 249 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLL-KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 + D TPLH+AA G + V LLL ++ + + + G TP+ A ++ E VK+ Sbjct: 250 SYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKV 307 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAG-AAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 R LH+A G + +LLE + D TPLHYAA E V + LKH + Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVK 315 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +L+G+T A D+V++ + Sbjct: 316 DDSDLEGRTSFMWAAGKGSDDVLRTM 341 Score = 38.5 bits (88), Expect = 0.019 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE---LKCAEILLEAGAAVD 364 +H +A + E +K + +N DVEG+ LH+A + + + +L+A Sbjct: 153 LHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTES 212 Query: 363 AL---DKNKNTPLHYAAGYGRKECVDLLLKHGAA--VMLQNLDGKTPIEVAKLNSQDEVV 199 L D TPLH+A G VD+L + + NL +TP+ A L ++V Sbjct: 213 LLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNL-FRTPLHWAALLGHAQIV 271 Query: 198 KLL 190 LL Sbjct: 272 HLL 274 Score = 32.0 bits (71), Expect = 1.8 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD--LLLK 283 D +G LH+A + ++ L+ + D D T +AAG G + + L LK Sbjct: 286 DSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLK 345 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + + G T + A L+ VKLL Sbjct: 346 SDIDINMADKYGGTALHAAALSGHVSTVKLL 376
>CTTB2_HUMAN (Q8WZ74) Cortactin-binding protein 2 (CortBP2)| Length = 1663 Score = 62.8 bits (151), Expect = 9e-10 Identities = 36/87 (41%), Positives = 48/87 (55%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G AL+ A G C +LL A A V+A DKN TPL AA G ECV+LL+ + A Sbjct: 743 DGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDAN 802 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + G+TP+ +A N E +KLL Sbjct: 803 INHAADGGQTPLYLACKNGNKECIKLL 829 Score = 56.6 bits (135), Expect = 7e-08 Identities = 34/117 (29%), Positives = 54/117 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +++ A G + ++ L A + D G L A G +C E+L+ A ++ Sbjct: 746 SALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANINH 805 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A G KEC+ LLL+ G ++ DG TP+ A + +KLL Sbjct: 806 AADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLL 862 Score = 39.7 bits (91), Expect = 0.009 Identities = 24/81 (29%), Positives = 39/81 (48%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ G E ++ + AN + G+ L+ AC G +C ++LLEAG + Sbjct: 785 AAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGW 844 Query: 342 TPLHYAAGYGRKECVDLLLKH 280 TP+H A G + + LL+ H Sbjct: 845 TPVHAAVDTGNVDSLKLLMYH 865 Score = 33.9 bits (76), Expect = 0.47 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 L A G + +LL E G ++ ++ ++ L+ AA G +CV LLL A V Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + +G TP+ A E V+LL Sbjct: 774 DKNGFTPLCAAAAQGHFECVELL 796
>MYPT2_MOUSE (Q8BG95) Protein phosphatase 1 regulatory subunit 12B (Myosin| phosphatase-targeting subunit 2) (Fragment) Length = 484 Score = 62.8 bits (151), Expect = 9e-10 Identities = 40/112 (35%), Positives = 61/112 (54%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 S GD + +KK L GA+ + +V+G ALH AC L + L+E A V+ D T Sbjct: 67 SSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 PLH AA G + + HGA+V + N +G+ P ++A+ + ++ LLEQ Sbjct: 127 PLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDL--LLEQ 176 Score = 47.0 bits (110), Expect = 5e-05 Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A G + +L++AG ++ D + TPLH AA +G KE +L + + Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDHDGWTPLHAAAHWGVKEACSILAEALCDM 276 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKL-LEQDVFL*SKPSDPVLID 139 ++N G+TP +VA + + L +QDV K + LI+ Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLEMLQKKQDVLRSEKETRNKLIE 320
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 62.8 bits (151), Expect = 9e-10 Identities = 39/108 (36%), Positives = 55/108 (50%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E + L GA+ + G ALH A G + AE+LL+ GA V+ D TPLH A Sbjct: 114 ELITSLLHSGADVQQVGYGGLTALHIAAIAGHPEAAEVLLQHGANVNVQDAVFFTPLHIA 173 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 A YG ++ +LLK GA V + G P+ +A +VKLL ++ Sbjct: 174 AYYGHEQVTSVLLKFGADVNVSGEVGDRPLHLASAKGFFNIVKLLVEE 221 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 2/119 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E + L GAN + +D LH A YG + +LL+ GA V+ Sbjct: 137 LHIAAIAGHPEAAEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNVSG 196 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHG--AAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + + PLH A+ G V LL++ G A V Q+ + P+ +V L Q Sbjct: 197 EVGDRPLHLASAKGFFNIVKLLVEEGSKADVNAQDNEDHVPLHFCSRFGHHNIVSYLLQ 255 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/86 (33%), Positives = 42/86 (48%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A + LL +GA V + T LH AA G E ++LL+HGA V Sbjct: 100 GFPALHLAVYKDSPELITSLLHSGADVQQVGYGGLTALHIAAIAGHPEAAEVLLQHGANV 159 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +Q+ TP+ +A ++V +L Sbjct: 160 NVQDAVFFTPLHIAAYYGHEQVTSVL 185 Score = 33.5 bits (75), Expect = 0.61 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGE-LKCAEILLEAGAA-VDALDKNKNTPLHYAAGYGRK 307 G + +E++ A H AC YG+ + + LL+ A ++ ++ +T LH A +G Sbjct: 293 GTESLTKENIFSETAFHSACTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHGHI 352 Query: 306 ECVDLLLKHGAAVMLQNLD 250 V LL +GA + L D Sbjct: 353 RLVQFLLDNGADMNLVACD 371
>CTTB2_MICMU (Q2QL82) Cortactin-binding protein 2 (CortBP2)| Length = 1647 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/87 (41%), Positives = 48/87 (55%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G AL+ A G C +LL A A V+A DKN TPL AA G ECV+LL+ + A Sbjct: 729 DGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDAN 788 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + G+TP+ +A N E +KLL Sbjct: 789 INHAADGGQTPLYLACKNGNKECIKLL 815 Score = 56.2 bits (134), Expect = 9e-08 Identities = 34/117 (29%), Positives = 55/117 (47%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +++ A G + ++ L+ A + D G L A G +C E+L+ A ++ Sbjct: 732 SALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINH 791 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A G KEC+ LLL+ G ++ DG TP+ A + +KLL Sbjct: 792 AADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGWTPVHAAVDTGNVDSLKLL 848 Score = 43.1 bits (100), Expect = 8e-04 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 1/107 (0%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ G E ++ + AN + G+ L+ AC G +C ++LLEAG ++ Sbjct: 771 AAQGHFECVELLIAYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTDRSVKTRDGW 830 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTP-IEVAKLNSQDE 205 TP+H A G + + LL+ H A +L+ + P +V+ L+ +E Sbjct: 831 TPVHAAVDTGNVDSLKLLMYHRAPAHGNSLNEEEPESDVSDLDDGEE 877 Score = 33.9 bits (76), Expect = 0.47 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 L A G + +LL E G ++ ++ ++ L+ AA G +CV LLL A V Sbjct: 700 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAA 759 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + +G TP+ A E V+LL Sbjct: 760 DKNGFTPLCAAAAQGHFECVELL 782
>EHMT1_HUMAN (Q9H9B1) Histone-lysine N-methyltransferase, H3 lysine-9 specific 5| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a-like protein 1) (GLP1) Length = 1267 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/96 (38%), Positives = 56/96 (58%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 +K L G++ + D E LH+A G + AEILL A + A++ + ++PLH AA Sbjct: 858 VKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAAR 917 Query: 318 YGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 R +CV L L + V L+N +G+TP++ A LNSQ Sbjct: 918 ENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQ 953 Score = 50.1 bits (118), Expect = 6e-06 Identities = 40/118 (33%), Positives = 54/118 (45%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G + + GAN D + R L A L+ + L++AGA VD Sbjct: 744 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 803 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D +T LH AA G E V LL +G V Q+ G TP+ A ++VKLL Sbjct: 804 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLL 861 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/85 (34%), Positives = 44/85 (51%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVM 265 R LH A G + +L++AGA +D +++ TPL AA E V L+K GA V Sbjct: 743 RSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVD 802 Query: 264 LQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ +G T + +A EVV+ L Sbjct: 803 PKDAEGSTCLHLAAKKGHYEVVQYL 827 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDALDKNKNTPLHY 328 E +K + GA D +D EG LH A G + + LL G V+ D TP+ + Sbjct: 789 EAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIW 848 Query: 327 AAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A Y + V LLL G+ + +++ + + A + ++ ++L Sbjct: 849 ATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEIL 894 Score = 40.8 bits (94), Expect = 0.004 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 7/91 (7%) Frame = -3 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALD-------KNKNTPLHYAAGYGRKECVDLLLK 283 + L+F+ GEL+ ++L VD +D +NK +PLH AA G + +L++ Sbjct: 709 KQLYFSARQGELQKVLLML-----VDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQ 763 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 GA + + D +TP+ A N+ E VK L Sbjct: 764 AGANIDTCSEDQRTPLMEAAENNHLEAVKYL 794
>ASB7_MOUSE (Q91ZU0) Ankyrin repeat and SOCS box protein 7 (ASB-7)| Length = 318 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/121 (33%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEED-VEGRRALHFACGYGELKCAEILLEAGAAVD 364 +++H +A+ G ++ L+ GA+ +D + G ALH+A +G + A ++LE+ D Sbjct: 49 TLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSD 108 Query: 363 ALDKNKN---TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 ++ N TPLH AA YGR V LLL+ A V + G TP+++A + + VK+ Sbjct: 109 IINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKI 168 Query: 192 L 190 L Sbjct: 169 L 169 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 + + GD ++K L+ G + + D G LHF+ G+ +C + LE GA D Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77 Query: 354 K-NKNTPLHYAAGYGRKECVDLLLK---HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LHYAA +GR L+L+ + ++ DG TP+ VA +D V+LL Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLL 136 Score = 45.4 bits (106), Expect = 2e-04 Identities = 26/65 (40%), Positives = 31/65 (47%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G LH A YG +LLE A VD L TPL A R CV +LL H A Sbjct: 116 DGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNAN 175 Query: 270 VMLQN 256 + +QN Sbjct: 176 IDIQN 180 Score = 31.6 bits (70), Expect = 2.3 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD-ALDKNKNTPLHYAA 322 +K LD AN D ++ L +A + L+ GA + ++ TPLH +A Sbjct: 166 VKILLDHNANID---IQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSA 222 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 C +L +GA +N +G+TP+ V+ Sbjct: 223 LRDDVLCARMLYNYGADTNTRNYEGQTPLAVS 254
>ASB7_MACFA (Q9BGT9) Ankyrin repeat and SOCS box protein 7 (ASB-7)| Length = 318 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/121 (33%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEED-VEGRRALHFACGYGELKCAEILLEAGAAVD 364 +++H +A+ G ++ L+ GA+ +D + G ALH+A +G + A ++LE+ D Sbjct: 49 TLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSD 108 Query: 363 ALDKNKN---TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 ++ N TPLH AA YGR V LLL+ A V + G TP+++A + + VK+ Sbjct: 109 IINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKI 168 Query: 192 L 190 L Sbjct: 169 L 169 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 + + GD ++K L+ G + + D G LHF+ G+ +C + LE GA D Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77 Query: 354 K-NKNTPLHYAAGYGRKECVDLLLK---HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LHYAA +GR L+L+ + ++ DG TP+ VA +D V+LL Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLL 136 Score = 45.4 bits (106), Expect = 2e-04 Identities = 26/65 (40%), Positives = 31/65 (47%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G LH A YG +LLE A VD L TPL A R CV +LL H A Sbjct: 116 DGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNAN 175 Query: 270 VMLQN 256 + +QN Sbjct: 176 IDIQN 180 Score = 33.5 bits (75), Expect = 0.61 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD-ALDKNKNTPLHYAA 322 +K LD AN D ++ L +A + L+ GA D ++ TPLH +A Sbjct: 166 VKILLDHNANID---IQNGFLLRYAVIKSNHSYCRMFLQRGADTDLGRLEDGQTPLHLSA 222 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 C +L +GA +N +G+TP+ V+ Sbjct: 223 LRDDVLCARMLYNYGADTNTRNYEGQTPLAVS 254
>ASB7_HUMAN (Q9H672) Ankyrin repeat and SOCS box protein 7 (ASB-7)| Length = 318 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/121 (33%), Positives = 67/121 (55%), Gaps = 4/121 (3%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEED-VEGRRALHFACGYGELKCAEILLEAGAAVD 364 +++H +A+ G ++ L+ GA+ +D + G ALH+A +G + A ++LE+ D Sbjct: 49 TLLHFSAARGKERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSD 108 Query: 363 ALDKNKN---TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 ++ N TPLH AA YGR V LLL+ A V + G TP+++A + + VK+ Sbjct: 109 IINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKI 168 Query: 192 L 190 L Sbjct: 169 L 169 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 + + GD ++K L+ G + + D G LHF+ G+ +C + LE GA D Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77 Query: 354 K-NKNTPLHYAAGYGRKECVDLLLK---HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LHYAA +GR L+L+ + ++ DG TP+ VA +D V+LL Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLL 136 Score = 45.4 bits (106), Expect = 2e-04 Identities = 26/65 (40%), Positives = 31/65 (47%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G LH A YG +LLE A VD L TPL A R CV +LL H A Sbjct: 116 DGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNAN 175 Query: 270 VMLQN 256 + +QN Sbjct: 176 IDIQN 180 Score = 31.6 bits (70), Expect = 2.3 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 1/92 (1%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD-ALDKNKNTPLHYAA 322 +K LD AN D ++ L +A + L+ GA + ++ TPLH +A Sbjct: 166 VKILLDHNANID---IQNGFLLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSA 222 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 C +L +GA +N +G+TP+ V+ Sbjct: 223 LRDDVLCARMLYNYGADTNTRNYEGQTPLAVS 254
>ANKR6_HUMAN (Q9Y2G4) Ankyrin repeat domain-containing protein 6| Length = 692 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/115 (32%), Positives = 59/115 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G ++ L G + D +D + ALH A G + L+ G A+D D Sbjct: 46 LHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQD 105 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K+ NT LH A+ +G + LL+K GA V+ +N G T + +A NS + ++L Sbjct: 106 KDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL 160 Score = 59.7 bits (143), Expect = 8e-09 Identities = 37/115 (32%), Positives = 59/115 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H VG+ E + + G D +D +G ALH A +G + A++L++AGA V A + Sbjct: 79 LHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKN 138 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K NT LH A + +LL G+ L+N G T + VA + +++LL Sbjct: 139 KAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLL 193 Score = 56.6 bits (135), Expect = 7e-08 Identities = 34/115 (29%), Positives = 55/115 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H ++ + L G+ D ++ G LH A Y L +LL A +V + Sbjct: 145 LHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKN 204 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + +T LH AA K+ +LL+ GA + N G+TP+E A+ ++ EV LL Sbjct: 205 QAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 259 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/108 (32%), Positives = 50/108 (46%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E + + ++ GA + GR LH A G L +ILL+AG +D D T L Sbjct: 21 GQTENVVQLINKGA-RVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTAL 79 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 H A G E + L+ G A+ Q+ DG T + A + + KLL Sbjct: 80 HRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLL 127 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/115 (30%), Positives = 54/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G ++ K + GAN ++ G ALH AC + +LL AG+ D + Sbjct: 112 LHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKN 171 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +T LH AA Y + LLL +V +N G T + VA + +V K+L Sbjct: 172 NAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 226 Score = 37.4 bits (85), Expect = 0.042 Identities = 26/84 (30%), Positives = 36/84 (42%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A ++ L + E++ G ALH A K A+ILLEAGA ++ Sbjct: 178 LHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVN 237 Query: 354 KNKNTPLHYAAGYGRKECVDLLLK 283 TPL A + E LL K Sbjct: 238 NAGQTPLETARYHNNPEVALLLTK 261
>CTTB2_HORSE (Q2QLA2) Cortactin-binding protein 2 (CortBP2)| Length = 1665 Score = 62.0 bits (149), Expect = 2e-09 Identities = 36/87 (41%), Positives = 47/87 (54%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G AL+ A G C +LL A A VDA DKN TPL AA G +CV LL+ + A Sbjct: 744 DGHSALYSAAKNGHTDCVRLLLNAEAQVDAADKNGFTPLCAAAAQGHFKCVQLLIAYDAN 803 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + G+TP+ +A N E +KLL Sbjct: 804 INHAADGGQTPLYLACKNGNKECIKLL 830 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/117 (29%), Positives = 56/117 (47%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +++ A G + ++ L+ A D D G L A G KC ++L+ A ++ Sbjct: 747 SALYSAAKNGHTDCVRLLLNAEAQVDAADKNGFTPLCAAAAQGHFKCVQLLIAYDANINH 806 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A G KEC+ LLL+ G+ ++ DG TP+ A + +KLL Sbjct: 807 AADGGQTPLYLACKNGNKECIKLLLEAGSDRSIKTRDGWTPVHAAVDTGNVDSLKLL 863 Score = 40.4 bits (93), Expect = 0.005 Identities = 22/70 (31%), Positives = 36/70 (51%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G+ L+ AC G +C ++LLEAG+ ++ TP+H A G + + LL+ H A Sbjct: 811 GQTPLYLACKNGNKECIKLLLEAGSDRSIKTRDGWTPVHAAVDTGNVDSLKLLMYHRAPA 870 Query: 267 MLQNLDGKTP 238 +L + P Sbjct: 871 HGSSLHKEEP 880 Score = 32.0 bits (71), Expect = 1.8 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 L A G + +LL E G ++ ++ ++ L+ AA G +CV LLL A V Sbjct: 715 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVDAA 774 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + +G TP+ A + V+LL Sbjct: 775 DKNGFTPLCAAAAQGHFKCVQLL 797
>Y1861_PYRAE (Q8ZWC4) Hypothetical ANK-repeat protein PAE1861| Length = 256 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/106 (34%), Positives = 58/106 (54%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++H A GDA +K L+ G + + D G+ LH A + +C E+LL+ G V+ Sbjct: 127 SLLHLVA--GDAGLVKLLLEYGVDPNARDAHGKTPLHMASEHNCAQCVELLLKRGPDVNV 184 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 D TPLHYA +C+ LLL++GA + + G+TP+ A+ Sbjct: 185 KDGAGRTPLHYADDV---DCIKLLLRYGADLNAVDNMGRTPLHYAE 227 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 10/111 (9%) Frame = -3 Query: 528 NTASVGDAEGLKKALDGGANKDEEDV----------EGRRALHFACGYGELKCAEILLEA 379 + ++VG E L A G +K + G LH G L ++LLE Sbjct: 88 SASAVGVEEALYTAARNGCHKAVRYMLARGVRPGASHGESLLHLVAGDAGL--VKLLLEY 145 Query: 378 GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 G +A D + TPLH A+ + +CV+LLLK G V +++ G+TP+ A Sbjct: 146 GVDPNARDAHGKTPLHMASEHNCAQCVELLLKRGPDVNVKDGAGRTPLHYA 196 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/75 (40%), Positives = 41/75 (54%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 GE + LL G + D D TPL+YAA G VDLL+K GA ++ +GKTPI Sbjct: 13 GEAELLTRLLNEGCSPDVQDDYGRTPLYYAAERGDVGTVDLLIKAGADPNARDREGKTPI 72 Query: 234 EVAKLNSQDEVVKLL 190 +A + + V+ LL Sbjct: 73 IIATQSRKFGVIPLL 87 Score = 45.8 bits (107), Expect = 1e-04 Identities = 23/65 (35%), Positives = 39/65 (60%) Frame = -3 Query: 528 NTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKN 349 N A G+AE L + L+ G + D +D GR L++A G++ ++L++AGA +A D+ Sbjct: 8 NAARRGEAELLTRLLNEGCSPDVQDDYGRTPLYYAAERGDVGTVDLLIKAGADPNARDRE 67 Query: 348 KNTPL 334 TP+ Sbjct: 68 GKTPI 72 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/87 (32%), Positives = 45/87 (51%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + A+ ++ L G + + +D GR LH+A ++ C ++LL GA ++A+D Sbjct: 160 LHMASEHNCAQCVELLLKRGPDVNVKDGAGRTPLHYA---DDVDCIKLLLRYGADLNAVD 216 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGA 274 TPLHYA + LLK GA Sbjct: 217 NMGRTPLHYAED---GLAAEALLKRGA 240
>MYPT1_HUMAN (O14974) Protein phosphatase 1 regulatory subunit 12A (Myosin| phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) Length = 1030 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/108 (32%), Positives = 59/108 (54%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 S GD + + K L GA+ + +V+G ALH AC + + L+E GA ++ D Sbjct: 49 SSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 PLH AA G + + L+ GA V N +G TP+++A+ + +E+++ Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQ 156 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/99 (29%), Positives = 51/99 (51%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G N G ALH A G + ++L++AG V+ D + TPLH AA +G++E Sbjct: 188 GHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEA 247 Query: 300 VDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 +L+ + + + N G+T +VA ++++ LE+ Sbjct: 248 CRILVDNLCDMEMVNKVGQTAFDVA----DEDILGYLEE 282
>INVS_MOUSE (O89019) Inversin (Inversion of embryo turning protein)| (Nephrocystin-2) Length = 1062 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/105 (34%), Positives = 56/105 (53%), Gaps = 2/105 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--AGAAVDA 361 +H A G+ +K L AN ++D+E LH + + KC +LL+ A VD Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALLLKFMAPGEVDT 144 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 DKNK T LH++A Y E LL+KH + + + +++GK P+ A Sbjct: 145 QDKNKQTALHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWA 189 Score = 59.3 bits (142), Expect = 1e-08 Identities = 40/118 (33%), Positives = 62/118 (52%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGG-ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 S VH A GD L++ + G A +D+ED GR L + + CA+ LL+AGA V+ Sbjct: 16 SQVHAAAVNGDKGALQRLIVGNSALRDKEDRFGRTPLMYCVLADRVDCADALLKAGADVN 75 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D ++ T LH AA G + LLL A M ++L+ TP+ ++ + + + LL Sbjct: 76 KTDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSPKCLALL 133 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++H A G+A+ + ++ N + +D GR L A G + C +L+E A + Sbjct: 425 SLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNI 484 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGA--AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK T LH++ G + + LLL A M N + TP++ A L + EV++ + Sbjct: 485 QDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFM 543 Score = 53.5 bits (127), Expect = 6e-07 Identities = 31/103 (30%), Positives = 52/103 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G +K LD A D DV L AC G + L++ GA VD +D Sbjct: 361 LHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGGARVDLVD 420 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 ++ ++ LH+AA G + +L+++ +Q+ G+TP++ A Sbjct: 421 QDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCA 463 Score = 53.5 bits (127), Expect = 6e-07 Identities = 32/89 (35%), Positives = 47/89 (52%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A G + ++LL+ A VDA D K+TPL A G ++ + L+K G Sbjct: 354 DKYGGTALHAAALSGHVSTVKLLLDNDAQVDATDVMKHTPLFRACEMGHRDVIQTLIKGG 413 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A V L + DG + + A L +V ++L Sbjct: 414 ARVDLVDQDGHSLLHWAALGGNADVCQIL 442 Score = 50.4 bits (119), Expect = 5e-06 Identities = 26/73 (35%), Positives = 43/73 (58%), Gaps = 2/73 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYG 313 ++ A+ + +D EGR ALH++C G L ++LL+ A + ++ N+ TPL YA Sbjct: 476 MENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGE 535 Query: 312 RKECVDLLLKHGA 274 R E + +L+HGA Sbjct: 536 RHEVIQFMLEHGA 548 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/109 (28%), Positives = 54/109 (49%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G + ++ + GGA D D +G LH+A G +IL+E + D TP Sbjct: 400 MGHRDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTP 459 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA G C+ +L+++ A +Q+ +G+T + + N + +KLL Sbjct: 460 LQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLL 508 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 2/121 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VD 364 S VH + DA + L+ +D EGR LHFA G L ++L + + Sbjct: 196 SAVHTVRCILDAAPTESLLNW------QDYEGRTPLHFAVADGNLTVVDVLTSYESCNIT 249 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLL-KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 + D TPLH+AA G + V LLL ++ + + + G TP+ A ++ E VK+ Sbjct: 250 SYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFL 309 Query: 186 Q 184 Q Sbjct: 310 Q 310 Score = 40.0 bits (92), Expect = 0.007 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 2/101 (1%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L GA+ ++ D R ALH A G + ++LL A D + TPLH + + Sbjct: 68 LKAGADVNKTDHSRRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLSTRHRSP 127 Query: 306 ECVDLLLKHGA--AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +C+ LLLK A V Q+ + +T + + + E KLL Sbjct: 128 KCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHAKLL 168 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 1/86 (1%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAG-AAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 R LH+A G + +LLE + D TPLHYAA E V + L+H + Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLQHPSVK 315 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +L+G+T A D+V++ + Sbjct: 316 DDSDLEGRTSFMWAAGKGNDDVLRTM 341 Score = 37.7 bits (86), Expect = 0.032 Identities = 34/123 (27%), Positives = 54/123 (43%), Gaps = 8/123 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE---LKCAEILLEAGAAVD 364 +H +A + E K + +N DVEG+ LH+A + + + +L+A Sbjct: 153 LHWSAYYNNPEHAKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTES 212 Query: 363 AL---DKNKNTPLHYAAGYGRKECVDLLLKHGAA--VMLQNLDGKTPIEVAKLNSQDEVV 199 L D TPLH+A G VD+L + + NL +TP+ A L ++V Sbjct: 213 LLNWQDYEGRTPLHFAVADGNLTVVDVLTSYESCNITSYDNL-FRTPLHWAALLGHAQIV 271 Query: 198 KLL 190 LL Sbjct: 272 HLL 274 Score = 33.1 bits (74), Expect = 0.80 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD--LLLK 283 D +G LH+A + ++ L+ + D D T +AAG G + + L LK Sbjct: 286 DSQGATPLHYAAQSNFAETVKVFLQHPSVKDDSDLEGRTSFMWAAGKGNDDVLRTMLSLK 345 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + + G T + A L+ VKLL Sbjct: 346 SDIDINMSDKYGGTALHAAALSGHVSTVKLL 376
>MYPT1_MOUSE (Q9DBR7) Protein phosphatase 1 regulatory subunit 12A (Myosin| phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) Length = 1004 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/108 (32%), Positives = 59/108 (54%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 S GD + + K L GA+ + +V+G ALH AC + + L+E GA ++ D Sbjct: 49 SSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 PLH AA G + + L+ GA V N +G TP+++A+ + +E+++ Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQ 156 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/98 (29%), Positives = 51/98 (52%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A G + ++L++AG V+ D + TPLH AA +G++E +L+ + + Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSD 154 N G+T +VA + + +L ++ L S+ D Sbjct: 259 ETVNKVGQTAFDVADEDILGYLEELQKKQTLLHSEKRD 296
>NOTC4_MOUSE (P31695) Neurogenic locus notch homolog protein 4 precursor (Notch 4)| [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain] Length = 1964 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/96 (39%), Positives = 52/96 (54%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ D G+ ALH+A + A LL+AGA DA D + TPL AA G E Sbjct: 1720 ADVGARDKRGKTALHWAAAVNNARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQ 1779 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 LLL+ GAA L++ G P +VA+ S +++ LLE Sbjct: 1780 LLLELGAARGLRDQAGLAPGDVARQRSHWDLLTLLE 1815 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 2/111 (1%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDV-EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 +G+ E + LD GA V G LH A + A LLEAGA + D+ T Sbjct: 1605 LGNLEPWEPLLDRGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRT 1664 Query: 339 PLHYA-AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 PLH A A R+ C LL +V + DG TP+ +A + +++V+ L Sbjct: 1665 PLHTAVAADAREVCQLLLASRQTSVDARTEDGTTPLMLAARLAVEDLVEEL 1715 Score = 42.0 bits (97), Expect = 0.002 Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAG-AAVDAL 358 +H A ++ L+ GAN ++ D GR LH A + ++LL + +VDA Sbjct: 1633 LHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHTAVAADAREVCQLLLASRQTSVDAR 1692 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 ++ TPL AA ++ V+ L+ A V ++ GKT + A +N+ LL+ Sbjct: 1693 TEDGTTPLMLAARLAVEDLVEELIAARADVGARDKRGKTALHWAAAVNNARAARSLLQ 1750 Score = 39.3 bits (90), Expect = 0.011 Identities = 20/55 (36%), Positives = 31/55 (56%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA 370 +H A+V +A + L GA+KD +D + L A G ++ A++LLE GAA Sbjct: 1733 LHWAAAVNNARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQLLLELGAA 1787
>ANKR2_MOUSE (Q9WV06) Ankyrin repeat domain-containing protein 2 (Skeletal| muscle ankyrin repeat protein) (mArpp) Length = 328 Score = 61.6 bits (148), Expect = 2e-09 Identities = 44/142 (30%), Positives = 61/142 (42%), Gaps = 33/142 (23%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G E L+K L+ GA D +D A+H+AC G L+ +L GA + D Sbjct: 154 LHRASLEGHMEILEKLLENGATVDFQDRLDCTAMHWACRGGHLEVVRLLQSRGADTNVRD 213 Query: 354 KNKNTPLHYAAGYGRKECVD---------------------------------LLLKHGA 274 K +TPLH A G E V+ LLL HGA Sbjct: 214 KLLSTPLHVAVRTGHVEIVEHFLSLGLDINAKDREGDSALHDAVRLNRYKIIKLLLLHGA 273 Query: 273 AVMLQNLDGKTPIEVAKLNSQD 208 +M +NL GKTP ++ +L D Sbjct: 274 DMMAKNLAGKTPTDLVQLWQAD 295 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/106 (34%), Positives = 51/106 (48%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + + K L G + D D R ALH A G ++ E LLE GA VD D+ T + Sbjct: 128 GKMKVIDKYLADGGSADTCDEFRRTALHRASLEGHMEILEKLLENGATVDFQDRLDCTAM 187 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 H+A G E V LL GA +++ TP+ VA E+V+ Sbjct: 188 HWACRGGHLEVVRLLQSRGADTNVRDKLLSTPLHVAVRTGHVEIVE 233
>MYPT1_RAT (Q10728) Protein phosphatase 1 regulatory subunit 12A (Myosin| phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit) (MBSP) (Serine/threonine protein phosphatase PP1 smooth muscle reg Length = 1032 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/108 (32%), Positives = 59/108 (54%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 S GD + + K L GA+ + +V+G ALH AC + + L+E GA ++ D Sbjct: 49 SSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWI 108 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 PLH AA G + + L+ GA V N +G TP+++A+ + +E+++ Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQ 156 Score = 43.5 bits (101), Expect = 6e-04 Identities = 27/88 (30%), Positives = 48/88 (54%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A G + ++L++AG V+ D + TPLH AA +G++E +L+ + + Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDM 258 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 N G+T +VA ++++ LE+ Sbjct: 259 ETVNKVGQTAFDVA----DEDILGYLEE 282
>MYPT2_HUMAN (O60237) Protein phosphatase 1 regulatory subunit 12B (Myosin| phosphatase-targeting subunit 2) (Myosin phosphatase target subunit 2) Length = 982 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/112 (34%), Positives = 61/112 (54%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 S GD + ++K L GA+ + +V+G ALH AC L + L+E A V+ D T Sbjct: 67 SSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 PLH AA G + + HGA+V + N +G+ P ++A+ + ++ LLEQ Sbjct: 127 PLHAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLAEEPAMKDL--LLEQ 176 Score = 46.2 bits (108), Expect = 9e-05 Identities = 26/74 (35%), Positives = 41/74 (55%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A G + +L++AG ++ D + TPLH AA +G KE +L + + Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276 Query: 267 MLQNLDGKTPIEVA 226 ++N G+TP +VA Sbjct: 277 DIRNKLGQTPFDVA 290
>MIB1_BRARE (Q804S5) Ubiquitin ligase protein mib (EC 6.3.2.-) (Mind bomb| protein) Length = 1030 Score = 61.2 bits (147), Expect = 3e-09 Identities = 36/108 (33%), Positives = 55/108 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + LK L + + ED +G RA+H A E E+L GA ++A +K + TPL Sbjct: 475 GHVDVLKLLLKHSVDLEAEDKDGDRAVHHASFGDEGSVIEVLHRGGADLNARNKRRQTPL 534 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 H A G + V LL G LQ+ +G TP+ A +D+++ +L Sbjct: 535 HIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVL 582 Score = 50.8 bits (120), Expect = 4e-06 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 1/135 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALD-GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 VH+ AS GD + + L GGA+ + + + LH A G L+ + LL+ G Sbjct: 501 VHH-ASFGDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQ 559 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDV 178 D +TPLH A R + + +LL+ GA V + N +G + A L +++L Sbjct: 560 DSEGDTPLHDAISKKRDDMLSVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL--- 616 Query: 177 FL*SKPSDPVLIDPK 133 SK P ++D K Sbjct: 617 ---SKLPRPWIVDEK 628 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAG-AAVDALDKNKNTPLHYAAGYGRKECVDLL 289 DE+ +G ALH A ++ AE+L+ G A +D + N+ T LH A + V LL Sbjct: 626 DEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDVQNVNQQTALHLAVERQHTQIVRLL 685 Query: 288 LKHGAAVMLQNLDGKTPIEVA 226 ++ A + +Q+ DG TP+ A Sbjct: 686 VRAEAKLDVQDKDGDTPLHEA 706 Score = 38.9 bits (89), Expect = 0.015 Identities = 20/52 (38%), Positives = 29/52 (55%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 G AN D ++V + ALH A + +L+ A A +D DK+ +TPLH A Sbjct: 655 GNANLDVQNVNQQTALHLAVERQHTQIVRLLVRAEAKLDVQDKDGDTPLHEA 706 Score = 37.0 bits (84), Expect = 0.055 Identities = 22/86 (25%), Positives = 44/86 (51%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G A+ A G + ++LL+ ++A DK+ + +H+A+ +++L + GA + Sbjct: 464 GHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGDRAVHHASFGDEGSVIEVLHRGGADL 523 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N +TP+ +A +VVK L Sbjct: 524 NARNKRRQTPLHIAVNKGHLQVVKTL 549
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 1/107 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANK-DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G+A ++ LD N ++ D G LH+AC G E+L+ GA ++ +++ +TP Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 LH AA +G ++ V LL++ A + N G P+ A QD+V + Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAE 117 Score = 50.4 bits (119), Expect = 5e-06 Identities = 24/71 (33%), Positives = 43/71 (60%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A +G + LL+ A ++A++++ N PLHYA +G+ + + L+ +GA V + N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 255 LDGKTPIEVAK 223 G+ P++ AK Sbjct: 131 KYGEMPVDKAK 141 Score = 37.7 bits (86), Expect = 0.032 Identities = 18/58 (31%), Positives = 32/58 (55%) Frame = -3 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++V+ L Q Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 1/107 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANK-DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G+A ++ LD N ++ D G LH+AC G E+L+ GA ++ +++ +TP Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 LH AA +G ++ V LL++ A + N G P+ A QD+V + Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAE 117 Score = 50.4 bits (119), Expect = 5e-06 Identities = 24/71 (33%), Positives = 43/71 (60%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A +G + LL+ A ++A++++ N PLHYA +G+ + + L+ +GA V + N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 255 LDGKTPIEVAK 223 G+ P++ AK Sbjct: 131 KYGEMPVDKAK 141 Score = 37.7 bits (86), Expect = 0.032 Identities = 18/58 (31%), Positives = 32/58 (55%) Frame = -3 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++V+ L Q Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 1/107 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANK-DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G+A ++ LD N ++ D G LH+AC G E+L+ GA ++ +++ +TP Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 LH AA +G ++ V LL++ A + N G P+ A QD+V + Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAE 117 Score = 49.7 bits (117), Expect = 8e-06 Identities = 24/71 (33%), Positives = 43/71 (60%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A +G + LL+ A ++A++++ N PLHYA +G+ + + L+ +GA V + N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 255 LDGKTPIEVAK 223 G+ P++ AK Sbjct: 131 KYGEMPMDKAK 141 Score = 37.7 bits (86), Expect = 0.032 Identities = 18/58 (31%), Positives = 32/58 (55%) Frame = -3 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++V+ L Q Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>CTTB2_CALJA (Q2QLF8) Cortactin-binding protein 2 (CortBP2)| Length = 1662 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/87 (40%), Positives = 48/87 (55%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G AL+ A G C +LL A A V+A DKN TPL AA G ECV+LL+ + A Sbjct: 742 DGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDAN 801 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + G+TP+ +A N E ++LL Sbjct: 802 INHAADGGQTPLYLACKNGNKECIRLL 828 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/117 (29%), Positives = 54/117 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +++ A G + ++ L A + D G L A G +C E+L+ A ++ Sbjct: 745 SALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINH 804 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A G KEC+ LLL+ G ++ DG TP+ A + +KLL Sbjct: 805 AADGGQTPLYLACKNGNKECIRLLLEAGTDRSVKTTDGWTPVHAAVDTGNVDSLKLL 861 Score = 38.5 bits (88), Expect = 0.019 Identities = 24/81 (29%), Positives = 38/81 (46%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ G E ++ + AN + G+ L+ AC G +C +LLEAG + Sbjct: 784 AAQGHFECVELLIAYDANINHAADGGQTPLYLACKNGNKECIRLLLEAGTDRSVKTTDGW 843 Query: 342 TPLHYAAGYGRKECVDLLLKH 280 TP+H A G + + LL+ H Sbjct: 844 TPVHAAVDTGNVDSLKLLMYH 864 Score = 33.9 bits (76), Expect = 0.47 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 L A G + +LL E G ++ ++ ++ L+ AA G +CV LLL A V Sbjct: 713 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 772 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + +G TP+ A E V+LL Sbjct: 773 DKNGFTPLCAAAAQGHFECVELL 795
>CDN2C_HUMAN (P42773) Cyclin-dependent kinase 6 inhibitor (p18-INK6)| (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c) Length = 168 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 1/111 (0%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G+ E ++ L GAN D +D G +H A G L + LLE A V+ D N P Sbjct: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLP 106 Query: 336 LHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 LH AA G V+ L+KH A+ V +N G T ++A+L ++EVV L++ Sbjct: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VD 364 +++H+ A G + L+ L+ A+ + ED EG LH A G L+ E L++ A+ V Sbjct: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 + +T A YGR E V L+ +GA Sbjct: 132 HRNHKGDTACDLARLYGRNEVVSLMQANGA 161
>TRPA1_RAT (Q6RI86) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) Length = 1125 Score = 60.8 bits (146), Expect = 4e-09 Identities = 36/94 (38%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -3 Query: 462 EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLK 283 +ED +G LH+AC G LL +V + K+K +PLH+AA YGR LL+ Sbjct: 409 DEDNDGCTPLHYACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQ 468 Query: 282 HGAAVMLQN---LDGKTPIEVAKLNSQDEVVKLL 190 + L N L G TP+ +A N D+VV+LL Sbjct: 469 DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL 502 Score = 54.7 bits (130), Expect = 3e-07 Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 4/121 (3%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE----AGA 373 S +H GD + +K LD GA+ D + ALHFA G ++++ + Sbjct: 242 SPLHLAVQSGDLDMIKMCLDSGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSD 301 Query: 372 AVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 V+A+D N+ T LH A+ + + D L+ GA + + +G++P+ +A ++ +V L Sbjct: 302 IVNAVDGNQETLLHRASLFDHHDLADYLISVGADINSTDSEGRSPLILATASASWNIVNL 361 Query: 192 L 190 L Sbjct: 362 L 362 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 13/120 (10%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRAL-----------HFACGYGELKCAEILLEAGA--AVD 364 E K ++G + E ++ RR L H A G+++ ++++ + A++ Sbjct: 34 ESFKVDIEGDMCRLEAFIKNRRKLSKYEDENLCLLHHAAAEGQVELMQLIINGSSCEALN 93 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 +D NTPLH+AA + E V LL GA L+N + P+ +A +EV+K+L + Sbjct: 94 VMDDYGNTPLHWAAEKNQVESVKFLLSQGANPNLRNRNMMAPLHIAVQGMYNEVIKVLTE 153 Score = 43.9 bits (102), Expect = 5e-04 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL- 358 +H G + L + + + + LHFA YG + + LL+ + L Sbjct: 418 LHYACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLN 477 Query: 357 --DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D + TPLH AA G + V LLLK G A+ L + +G T + A + + +K++ Sbjct: 478 EGDLHGMTPLHLAAKNGHDKVVQLLLKKG-ALFLSDHNGWTALHHASMGGYTQTMKVI 534 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 8/101 (7%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + E G AL C + +ILLE GA + +K + P+H AA G K C++L Sbjct: 158 NINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKRCMEL 217 Query: 291 LLKHG--------AAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 +L +G A + N +P+ +A + +++K+ Sbjct: 218 ILAYGEKTGYSREAHINFVNHKKASPLHLAVQSGDLDMIKM 258 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -3 Query: 537 IVHNTASVGDAEGLKKALDGGANK--DEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 ++H+ A+ G E ++ ++G + + + D G LH+A +++ + LL GA + Sbjct: 67 LLHHAAAEGQVELMQLIINGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLSQGANPN 126 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++N PLH A E + +L +H A + L+ +G T + E +++L Sbjct: 127 LRNRNMMAPLHIAVQGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQIL 185 Score = 36.2 bits (82), Expect = 0.094 Identities = 31/108 (28%), Positives = 46/108 (42%), Gaps = 5/108 (4%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACG--YGELKCAEILLEAGAAVDAL---DKNKNTPLHYAA 322 L GA D +D GR LH YG L+ + + D + TPLHYA Sbjct: 363 LSKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFLQMQHIKELVMDEDNDGCTPLHYAC 422 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDV 178 G V+ LL+ +V ++ D K+P+ A + + L QD+ Sbjct: 423 RQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQDI 470
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 60.8 bits (146), Expect = 4e-09 Identities = 38/105 (36%), Positives = 52/105 (49%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E + L GA+ + G ALH A G + E+LL+ GA V+ D TPLH A Sbjct: 114 ELITSLLHSGADVQQAGYGGLTALHIAAIAGHPEAVEVLLQHGANVNVQDAVFFTPLHIA 173 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A YG ++ +LLK GA V + G P+ +A +VKLL Sbjct: 174 AYYGHEQVTSVLLKFGADVNVSGEVGDRPLHLASAKGFFNIVKLL 218 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/86 (36%), Positives = 43/86 (50%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH A L+ LL +GA V T LH AA G E V++LL+HGA V Sbjct: 100 GFPALHLAVYKDSLELITSLLHSGADVQQAGYGGLTALHIAAIAGHPEAVEVLLQHGANV 159 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +Q+ TP+ +A ++V +L Sbjct: 160 NVQDAVFFTPLHIAAYYGHEQVTSVL 185 Score = 46.2 bits (108), Expect = 9e-05 Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 1/118 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E ++ L GAN + +D LH A YG + +LL+ GA V+ Sbjct: 137 LHIAAIAGHPEAVEVLLQHGANVNVQDAVFFTPLHIAAYYGHEQVTSVLLKFGADVNVSG 196 Query: 354 KNKNTPLHYAAGYGRKECVDLLLK-HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + + PLH A+ G V LL++ + A V Q+ + P+ +V L Q Sbjct: 197 EVGDRPLHLASAKGFFNIVKLLVEGNKADVNAQDNEDHVPLHFCSRFGHHNIVSYLLQ 254 Score = 33.5 bits (75), Expect = 0.61 Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGE-LKCAEILLEAGAA-VDALDKNKNTPLHYAAGYGRK 307 G + +E++ A H AC YG+ + + LL+ A ++ ++ +T LH A +G Sbjct: 292 GTESLTKENIFSETAFHSACTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHGHI 351 Query: 306 ECVDLLLKHGAAVMLQNLD 250 V LL +GA + L D Sbjct: 352 RLVQFLLDNGADMNLVACD 370
>BARD1_MOUSE (O70445) BRCA1-associated RING domain protein 1 (BARD-1)| Length = 765 Score = 60.8 bits (146), Expect = 4e-09 Identities = 33/103 (32%), Positives = 54/103 (52%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H + GD ++ L G + + +D G LH AC +G LK E+LL+ A V+ Sbjct: 418 TLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHLKVVELLLQHNALVNT 477 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE 232 ++PLH A G + V +LL HGA+ N+ G P++ Sbjct: 478 PGYQNDSPLHDAVKSGHIDIVKVLLSHGASRNAVNIFGVRPVD 520 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/99 (30%), Positives = 46/99 (46%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L G + + G LH A G++ E LL+ G + D TPLH A +G Sbjct: 403 LSSGMPARKRNHRGETLLHIASIKGDIPSVEYLLQNGNDPNVKDHAGWTPLHEACSHGHL 462 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + V+LLL+H A V +P+ A + ++VK+L Sbjct: 463 KVVELLLQHNALVNTPGYQNDSPLHDAVKSGHIDIVKVL 501
>ASB3_MOUSE (Q9WV72) Ankyrin repeat and SOCS box protein 3 (ASB-3)| Length = 525 Score = 60.5 bits (145), Expect = 5e-09 Identities = 43/117 (36%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G+AE +K L GA+++ +D G L A YG+L+ IL+ +GA V+ Sbjct: 150 LHQASFQGNAETIKLLLKQGADRECQDDFGITPLFVAAQYGKLESMSILISSGANVNCQA 209 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ-NLDG-KTPIEVAKLNSQDEVVKLL 190 +K TPL AA G +CV+LLL GA L N D + PI A E + LL Sbjct: 210 LDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTETLDLL 266 Score = 56.2 bits (134), Expect = 9e-08 Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 1/109 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKD-EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G + LK L GAN + + G +LH A G + ++LL+ GA + D TP Sbjct: 123 GRIDVLKLLLQHGANVNGSHSMSGWNSLHQASFQGNAETIKLLLKQGADRECQDDFGITP 182 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA YG+ E + +L+ GA V Q LD TP+ +A + V+LL Sbjct: 183 LFVAAQYGKLESMSILISSGANVNCQALDKATPLFIAAQEGHTKCVELL 231 Score = 52.8 bits (125), Expect = 1e-06 Identities = 34/88 (38%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 EG ALH A G K +ILLEAGA + + TPL A GR + + LLL+HGA Sbjct: 78 EGFCALHLAVSQGHWKITQILLEAGADPNETTLEETTPLFLAVESGRIDVLKLLLQHGAN 137 Query: 270 VM-LQNLDGKTPIEVAKLNSQDEVVKLL 190 V ++ G + A E +KLL Sbjct: 138 VNGSHSMSGWNSLHQASFQGNAETIKLL 165 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL--DKN 349 A G E + + GAN + + ++ L A G KC E+LL +GA D + N Sbjct: 187 AQYGKLESMSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDN 246 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 P+H AA G E +DLL+ D +P+ A ++E +++L Q+ Sbjct: 247 WQLPIHAAAQMGHTETLDLLIPRTNRACDTEPDKVSPVYSAVFGGREECLEMLLQN 302 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/122 (27%), Positives = 57/122 (46%), Gaps = 3/122 (2%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA--- 370 S V A G+ + L+K L G + D D G +H A + ++C ++L+ ++ Sbjct: 12 STVGLAAREGNVKILRKLLKKGRSVDVADNRGWMPIHEAAYHNAVECLQMLIHTDSSENY 71 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + A LH A G + +LL+ GA L+ TP+ +A + + +V+KLL Sbjct: 72 IKAKTFEGFCALHLAVSQGHWKITQILLEAGADPNETTLEETTPLFLAVESGRIDVLKLL 131 Query: 189 EQ 184 Q Sbjct: 132 LQ 133
>ASB16_MOUSE (Q8VHS5) Ankyrin repeat and SOCS box protein 16 (ASB-16)| Length = 453 Score = 60.1 bits (144), Expect = 6e-09 Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 1/104 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD-AL 358 +H + + ++ L GA + EG LH L+CA++LLEAGA+V+ A Sbjct: 147 LHEACAQAHPDCVRLLLTFGAKANVSSEEGMTPLHLCTSPESLQCAKLLLEAGASVNVAS 206 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 +++ TPLH AA G ++ V L L++GA V L+ G+T + A Sbjct: 207 QESEVTPLHVAAARGLEQHVALYLQNGADVALRTSQGETALNAA 250 Score = 52.8 bits (125), Expect = 1e-06 Identities = 39/117 (33%), Positives = 55/117 (47%), Gaps = 8/117 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE--------LKCAEILLEA 379 +H A+ G + + L GA+ +G AL+ AC E A LLEA Sbjct: 214 LHVAAARGLEQHVALYLQNGADVALRTSQGETALNAACAGAEGPGSSRQHEAAARQLLEA 273 Query: 378 GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD 208 GA A + ++TPLH A G +LLL+HGA+ + N G TP++ A QD Sbjct: 274 GADPQAAGRKRHTPLHNACANGCGGLAELLLRHGASPGVTNGAGHTPMDCALQAVQD 330 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA D + GR ALH AC C +LL GA + + TPLH +C Sbjct: 134 GAELDAR-IGGRAALHEACAQAHPDCVRLLLTFGAKANVSSEEGMTPLHLCTSPESLQCA 192 Query: 297 DLLLKHGAAVMLQNLDGK-TPIEVAKLNSQDEVVKLLEQD 181 LLL+ GA+V + + + + TP+ VA ++ V L Q+ Sbjct: 193 KLLLEAGASVNVASQESEVTPLHVAAARGLEQHVALYLQN 232
>MIB_DROME (Q9VUX2) Ubiquitin ligase protein mind-bomb (EC 6.3.2.-) (Mind bomb| homolog) (D-mib) Length = 1226 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/108 (35%), Positives = 54/108 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E ++ L + + ED +G RA+H A E EIL +AGA ++A +K + T L Sbjct: 579 GHIEVIQVLLRHAVDVEIEDKDGDRAVHHAAFGDEAAVIEILAKAGADLNARNKRRQTSL 638 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 H A G V LL G LQ+ +G TP+ A DE++ LL Sbjct: 639 HIAVNKGHLNVVKTLLTLGCHPSLQDSEGDTPLHDAISKEHDEMLSLL 686 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/115 (28%), Positives = 50/115 (43%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 VH+ A +A ++ GA+ + + + +LH A G L + LL G D Sbjct: 605 VHHAAFGDEAAVIEILAKAGADLNARNKRRQTSLHIAVNKGHLNVVKTLLTLGCHPSLQD 664 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +TPLH A E + LLL GA + L N +G + A L +K+L Sbjct: 665 SEGDTPLHDAISKEHDEMLSLLLDFGADITLNNNNGFNALHHAALKGNPSAMKIL 719 Score = 42.7 bits (99), Expect = 0.001 Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 4/122 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H+ S E L LD GA+ + G ALH A G +ILL ++ Sbjct: 671 LHDAISKEHDEMLSLLLDFGADITLNNNNGFNALHHAALKGNPSAMKILLTKTNRPWIVE 730 Query: 354 KNKN---TPLHYAAGYGRKECVDLLLKHGAAVM-LQNLDGKTPIEVAKLNSQDEVVKLLE 187 + K+ T LH AA E +LL+ G A M QN++ +T + +A ++VKLL Sbjct: 731 EKKDDGYTALHLAALNNHVEIAELLVHMGKANMDRQNVNLQTALHLAVERQHVQIVKLLV 790 Query: 186 QD 181 QD Sbjct: 791 QD 792 Score = 38.1 bits (87), Expect = 0.025 Identities = 19/52 (36%), Positives = 32/52 (61%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 G AN D ++V + ALH A ++ ++L++ GA ++ DK+ +TPLH A Sbjct: 759 GKANMDRQNVNLQTALHLAVERQHVQIVKLLVQDGADLNIPDKDGDTPLHEA 810 Score = 38.1 bits (87), Expect = 0.025 Identities = 24/86 (27%), Positives = 41/86 (47%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G AL A G ++ ++LL V+ DK+ + +H+AA +++L K GA + Sbjct: 568 GHTALQAASQNGHIEVIQVLLRHAVDVEIEDKDGDRAVHHAAFGDEAAVIEILAKAGADL 627 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 +N +T + +A VVK L Sbjct: 628 NARNKRRQTSLHIAVNKGHLNVVKTL 653
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 60.1 bits (144), Expect = 6e-09 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 1/107 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANK-DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G+A ++ LD N ++ D G LH+AC G E+L+ GA ++ +++ +TP Sbjct: 11 GNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTP 70 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 LH AA +G ++ V LL++ A N G P+ A QD+V + Sbjct: 71 LHLAASHGHRDIVQKLLQYKADTNAVNEHGNVPLHYACFWGQDQVAE 117 Score = 49.3 bits (116), Expect = 1e-05 Identities = 24/71 (33%), Positives = 42/71 (59%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A +G + LL+ A +A++++ N PLHYA +G+ + + L+ +GA V + N Sbjct: 71 LHLAASHGHRDIVQKLLQYKADTNAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICN 130 Query: 255 LDGKTPIEVAK 223 G+ P++ AK Sbjct: 131 KYGEMPVDKAK 141 Score = 37.7 bits (86), Expect = 0.032 Identities = 18/58 (31%), Positives = 32/58 (55%) Frame = -3 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 D + +PLH+A GR V++L+ GA + + N TP+ +A + ++V+ L Q Sbjct: 31 DDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQ 88
>CTTB2_CALMO (Q2QLB3) Cortactin-binding protein 2 (CortBP2)| Length = 1663 Score = 60.1 bits (144), Expect = 6e-09 Identities = 35/87 (40%), Positives = 47/87 (54%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +G AL+ A G C +LL A A V+A D N TPL AA G ECV+LL+ + A Sbjct: 743 DGHSALYSAAKNGHTDCVRLLLSAEAQVNAADTNGFTPLCAAAAQGHFECVELLIAYDAN 802 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + G+TP+ +A N E +KLL Sbjct: 803 INHAAGGGQTPLYLACKNGNKECIKLL 829 Score = 56.6 bits (135), Expect = 7e-08 Identities = 34/117 (29%), Positives = 54/117 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +++ A G + ++ L A + D G L A G +C E+L+ A ++ Sbjct: 746 SALYSAAKNGHTDCVRLLLSAEAQVNAADTNGFTPLCAAAAQGHFECVELLIAYDANINH 805 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A G KEC+ LLL+ G ++ DG TP+ A + +KLL Sbjct: 806 AAGGGQTPLYLACKNGNKECIKLLLEAGTDRCVKTTDGWTPVHAAVDTGNVDSLKLL 862 Score = 34.3 bits (77), Expect = 0.36 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 L A G + +LL E G ++ ++ ++ L+ AA G +CV LLL A V Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + +G TP+ A E V+LL Sbjct: 774 DTNGFTPLCAAAAQGHFECVELL 796
>PP16A_MOUSE (Q923M0) Protein phosphatase 1 regulatory subunit 16A (Myosin| phosphatase targeting subunit 3) Length = 524 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/104 (36%), Positives = 57/104 (54%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 L+ L GAN + G LH A G + A +LLE GA++ A D + PLH AA Sbjct: 215 LQNRLQAGANLSDPLDHGATLLHIAAANGFSEVATLLLEQGASLSAKDHDGWEPLHAAAY 274 Query: 318 YGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 +G+ V+LL+ HGA + ++L +TP++V ++ KLLE Sbjct: 275 WGQVHLVELLVAHGADLNGKSLVDETPLDVC--GDEEVRAKLLE 316 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/100 (35%), Positives = 54/100 (54%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ D E +++ L G + + + +G ALH C + A+ LL+AGA V+A D Sbjct: 79 AARNDLEEVRQFLTSGVSPNLANEDGLTALHQCCIDDFQEMAQQLLDAGADVNARDSECW 138 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 TPLH AA G V+LL+ GA ++ N DG P ++ + Sbjct: 139 TPLHAAATCGHLHLVELLISRGADLLAVNSDGNMPYDLCE 178 Score = 33.9 bits (76), Expect = 0.47 Identities = 20/70 (28%), Positives = 33/70 (47%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E ++ LD GA+ + D E LH A G L E+L+ GA + A++ + N P Sbjct: 118 EMAQQLLDAGADVNARDSECWTPLHAAATCGHLHLVELLISRGADLLAVNSDGNMPYDLC 177 Query: 324 AGYGRKECVD 295 +C++ Sbjct: 178 EDAQTLDCLE 187
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 60.1 bits (144), Expect = 6e-09 Identities = 34/110 (30%), Positives = 52/110 (47%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + LK + D +D G ALH A YG ++L G+ D DK + TPL Sbjct: 423 GHVDTLKFLNENKCPLDVKDKSGETALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPL 482 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 H AA +G L + G V ++N +G+TP+ A ++V+ L + Sbjct: 483 HCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAE 532 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/115 (31%), Positives = 56/115 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G A+ ++ G+N D +D E LH A +G A+ L E G V+ + Sbjct: 449 LHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKALCEVGCNVNIKN 508 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPL A+ G + V+ L +HGA + + DG + +A Q EV+K L Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNASDKDGHIALHLAVRRCQMEVIKTL 563 Score = 56.2 bits (134), Expect = 9e-08 Identities = 38/105 (36%), Positives = 47/105 (44%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E +K L G+ D +D G LH AC G L EA +D +K TPLH A Sbjct: 558 EVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCEASCNLDISNKYGRTPLHLA 617 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A G + V L GA V DGKT ++AK + V LL Sbjct: 618 ANNGILDVVRYLCLMGANVEALTSDGKTAEDLAKAEQHEHVAGLL 662 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/111 (29%), Positives = 54/111 (48%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A G+ + L+ + G+ D +D G A+++A +G + + L E +D DK+ Sbjct: 387 AGCGNIQMLQLLIKRGSRIDVQDKGGSNAIYWASRHGHVDTLKFLNENKCPLDVKDKSGE 446 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LH AA YG + V LL G+ Q+ + +TP+ A + V K L Sbjct: 447 TALHVAARYGHADVVQLLCSFGSNPDFQDKEEETPLHCAAWHGYYSVAKAL 497 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/96 (33%), Positives = 50/96 (52%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + D +G ALH A +++ + LL G+ VD D++ NTPLH A G V Sbjct: 534 GADLNASDKDGHIALHLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIV 593 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L + + + N G+TP+ +A N +VV+ L Sbjct: 594 VALCEASCNLDISNKYGRTPLHLAANNGILDVVRYL 629 Score = 48.9 bits (115), Expect = 1e-05 Identities = 40/117 (34%), Positives = 54/117 (46%), Gaps = 1/117 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G K + G N + ++ EG L A G E L E GA ++A D Sbjct: 482 LHCAAWHGYYSVAKALCEVGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNASD 541 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQDEVVKLLE 187 K+ + LH A + E + LL HG+ V Q+ G TP+ VA K S VV L E Sbjct: 542 KDGHIALHLAVRRCQMEVIKTLLGHGSFVDFQDRHGNTPLHVACKDGSAPIVVALCE 598
>FANK1_RAT (Q66H07) Fibronectin type 3 and ankyrin repeat domains 1 protein| Length = 344 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/110 (34%), Positives = 62/110 (56%), Gaps = 2/110 (1%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-TP 337 G + +K GA+ D D+ G ALH+A G + +++ G VD +D TP Sbjct: 188 GHLDVVKYLRKHGASWDARDLGGCTALHWAADGGHCPVIDWMIKDGCEVDVVDTGSGWTP 247 Query: 336 L-HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L +A G ++ LL++ GA V +++ DGKTP+ VA LN+ +++V+LL Sbjct: 248 LMRVSAVTGSQKVASLLIEAGADVNVRDKDGKTPLMVAVLNNHEQLVQLL 297 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/77 (38%), Positives = 45/77 (58%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G K A +L+EAGA V+ DK+ TPL A ++ V LLL GA ++N GK + Sbjct: 256 GSQKVASLLIEAGADVNVRDKDGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVL 315 Query: 234 EVAKLNSQDEVVKLLEQ 184 E+A++ + V+ LLE+ Sbjct: 316 EMARVFDRQNVLSLLEE 332
>PP16A_HUMAN (Q96I34) Protein phosphatase 1 regulatory subunit 16A (Myosin| phosphatase-targeting subunit 3) Length = 528 Score = 59.7 bits (143), Expect = 8e-09 Identities = 35/103 (33%), Positives = 54/103 (52%) Frame = -3 Query: 537 IVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 ++ A+ D E +++ L G + D + +G ALH C + + LLEAGA ++A Sbjct: 74 VLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINAC 133 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEV 229 D TPLH AA G V+LL+ GA ++ N DG P ++ Sbjct: 134 DSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDL 176 Score = 54.7 bits (130), Expect = 3e-07 Identities = 35/106 (33%), Positives = 57/106 (53%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 + ++ L GA+ G LH A G + A +LLE A++ A D++ PLH A Sbjct: 213 DDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAA 272 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 A +G+ V+LL+ HGA + ++L +TP++V ++ KLLE Sbjct: 273 AYWGQVPLVELLVAHGADLNAKSLMDETPLDVC--GDEEVRAKLLE 316 Score = 32.7 bits (73), Expect = 1.0 Identities = 20/70 (28%), Positives = 35/70 (50%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E +++ L+ GAN + D E LH A G L E+L+ +GA + A++ + N P Sbjct: 118 EMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLC 177 Query: 324 AGYGRKECVD 295 +C++ Sbjct: 178 DDEQTLDCLE 187
>ACBD6_RAT (Q5RJK8) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 59.7 bits (143), Expect = 8e-09 Identities = 33/88 (37%), Positives = 48/88 (54%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D EGR LH+AC G + ++LL+ A ++ D T LHYAA + V+LLL+ G Sbjct: 189 DEEGRALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELLLQSG 248 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 A L++ DG P EV + V++L Sbjct: 249 ADPTLRDQDGCLPEEVTGCKAVSLVLQL 276 Score = 36.2 bits (82), Expect = 0.094 Identities = 24/77 (31%), Positives = 38/77 (49%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V+ D+ LH+A G KE V +LL+ A + Q+ +G+T + A ++V+LL Sbjct: 185 VNMTDEEGRALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELL 244 Query: 189 EQDVFL*SKPSDPVLID 139 Q +DP L D Sbjct: 245 LQ------SGADPTLRD 255 Score = 30.4 bits (67), Expect = 5.2 Identities = 20/68 (29%), Positives = 33/68 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H G E +K L A + +D EG+ ALH+A E+LL++GA Sbjct: 194 ALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELLLQSGADPTL 253 Query: 360 LDKNKNTP 337 D++ P Sbjct: 254 RDQDGCLP 261
>OSBL1_RAT (Q8K4M9) Oxysterol-binding protein-related protein 1 (OSBP-related| protein 1) (ORP-1) Length = 950 Score = 59.7 bits (143), Expect = 8e-09 Identities = 43/119 (36%), Positives = 64/119 (53%), Gaps = 10/119 (8%) Frame = -3 Query: 513 GDAEGLKKALDGGANKD---EEDVEGRRA-------LHFACGYGELKCAEILLEAGAAVD 364 G+AE ++K L+ A + + D +GR LH AC +G + + LL+AGA V+ Sbjct: 16 GNAEEVRKLLEAMARAEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVQDLLKAGAKVN 75 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 L+ +TPLH AA GRKE V LLL++ A + N G+T E E+ ++LE Sbjct: 76 MLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTVVNGSGQTAKEA---THDKEIRQMLE 131 Score = 38.9 bits (89), Expect = 0.015 Identities = 20/48 (41%), Positives = 30/48 (62%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 V+ D+ NTPLH AA K+CV LL+ GA L+N + + P+++A Sbjct: 169 VNCSDQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLA 216
>ACBD6_XENLA (Q4V869) Acyl-CoA-binding domain-containing protein 6| Length = 286 Score = 59.7 bits (143), Expect = 8e-09 Identities = 33/84 (39%), Positives = 44/84 (52%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + + D EGR LH+AC G + ++L A ++ D TPLHYA+ + Sbjct: 172 GSVDVNVADDEGRSLLHWACDRGHTQLVSVILFHNAHINMQDSEGQTPLHYASACEFPDI 231 Query: 300 VDLLLKHGAAVMLQNLDGKTPIEV 229 VDLLL HGA L + DG P EV Sbjct: 232 VDLLLDHGADPSLVDNDGFQPHEV 255 Score = 38.1 bits (87), Expect = 0.025 Identities = 22/77 (28%), Positives = 38/77 (49%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V+ D + LH+A G + V ++L H A + +Q+ +G+TP+ A ++V LL Sbjct: 176 VNVADDEGRSLLHWACDRGHTQLVSVILFHNAHINMQDSEGQTPLHYASACEFPDIVDLL 235 Query: 189 EQDVFL*SKPSDPVLID 139 +DP L+D Sbjct: 236 L------DHGADPSLVD 246
>TRPA1_MOUSE (Q8BLA8) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) Length = 1125 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/94 (37%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -3 Query: 462 EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLK 283 +ED +G LH+AC G LL ++ + K+K +PLH+AA YGR LL+ Sbjct: 409 DEDNDGCTPLHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ 468 Query: 282 HGAAVMLQN---LDGKTPIEVAKLNSQDEVVKLL 190 + L N L G TP+ +A N D+VV+LL Sbjct: 469 DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL 502 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/121 (27%), Positives = 61/121 (50%), Gaps = 4/121 (3%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE----AGA 373 S +H GD + +K LD GA+ D + ALHFA G ++++ + Sbjct: 242 SPLHLAVQSGDLDMIKMCLDNGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSD 301 Query: 372 AVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 V+A+D N+ T LH A+ + + + L+ GA + + +G++P+ +A ++ +V L Sbjct: 302 IVNAVDGNQETLLHRASLFDHHDLAEYLISVGADINSTDSEGRSPLILATASASWNIVNL 361 Query: 192 L 190 L Sbjct: 362 L 362 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 3/85 (3%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDAL---DKNKNTPLHYAAGYGRKECVDLLLKHGAAVM 265 LHFA YG + + LL+ + L D + TPLH AA G + V LLLK G A+ Sbjct: 451 LHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKG-ALF 509 Query: 264 LQNLDGKTPIEVAKLNSQDEVVKLL 190 L + +G T + A + + +K++ Sbjct: 510 LSDHNGWTALHHASMGGYTQTMKVI 534 Score = 41.2 bits (95), Expect = 0.003 Identities = 23/65 (35%), Positives = 35/65 (53%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + E G AL C + +ILLE GA + +K + P+H AA G K+C++L Sbjct: 158 NINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKKCMEL 217 Query: 291 LLKHG 277 +L +G Sbjct: 218 ILAYG 222 Score = 35.0 bits (79), Expect = 0.21 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 2/52 (3%) Frame = -3 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLD--GKTPIEVAKLNSQDEVVKLL 190 PLH+AA G+ E ++L++ + +L +D G TP+ A +Q E VK L Sbjct: 67 PLHHAAAEGQVELMELIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFL 118 Score = 32.0 bits (71), Expect = 1.8 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 5/105 (4%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACG--YGELKCAEILLEAGAAVDAL---DKNKNTPLHYAAGYG 313 GA D +D GR LH YG ++ + + D + TPLHYA G Sbjct: 366 GAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKELVMDEDNDGCTPLHYACRQG 425 Query: 312 RKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDV 178 V+ LL ++ ++ D K+P+ A + + L QD+ Sbjct: 426 VPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDI 470
>TRPA1_HUMAN (O75762) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120) Length = 1119 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/94 (37%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -3 Query: 462 EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLK 283 +ED +G LH+AC G LL ++ + K+K +PLH+AA YGR LL+ Sbjct: 408 DEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ 467 Query: 282 HGAAVMLQN---LDGKTPIEVAKLNSQDEVVKLL 190 + L N L G TP+ +A N D+VV+LL Sbjct: 468 DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL 501 Score = 49.7 bits (117), Expect = 8e-06 Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 4/119 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA----V 367 +H GD E +K LD GA D + A+HFA G + ++++ + + V Sbjct: 243 LHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIV 302 Query: 366 DALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + D T LH A+ + E D L+ GA + + +G++P+ +A ++ +V LL Sbjct: 303 NTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLL 361 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGA-AVDALDKNKNTPLHYAAGYGRKECVDLLLKH 280 D G ALH A G + +++L+ D LD++ NT LH+AA G + V LLL H Sbjct: 511 DHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSH 570 Query: 279 GAAVMLQNLDGKTPIEVAKLNSQDEVV 199 A ++L N + + +A N + EVV Sbjct: 571 NADIVL-NKQQASFLHLALHNKRKEVV 596 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL- 358 +H G + L + + + + LHFA YG + + LL+ + L Sbjct: 417 LHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLLN 476 Query: 357 --DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D + TPLH AA G + V LLLK G A+ L + +G T + A + + +K++ Sbjct: 477 EGDLHGMTPLHLAAKNGHDKVVQLLLKKG-ALFLSDHNGWTALHHASMGGYTQTMKVI 533 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 8/97 (8%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKH 280 E G A+ AC + +ILL GA +K P+H AA G KEC++++L+ Sbjct: 161 EGENGNTAVIIACTTNNSEALQILLNKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRF 220 Query: 279 GAA--------VMLQNLDGKTPIEVAKLNSQDEVVKL 193 G + N TP+ +A N E++K+ Sbjct: 221 GEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKM 257 Score = 40.0 bits (92), Expect = 0.007 Identities = 31/118 (26%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANK--DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +H A+ G E ++K + + E D G LH A +++ + LL GA + Sbjct: 67 LHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNL 126 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + N PLH A E + +LL+H V L+ +G T + +A + E +++L Sbjct: 127 RNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQIL 184 Score = 33.5 bits (75), Expect = 0.61 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 5/108 (4%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACG--YGELKCAEILLEAGAAVDAL---DKNKNTPLHYAA 322 L GA D +D GR LH YG ++ + + D + TPLHYA Sbjct: 362 LSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYAC 421 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDV 178 G V+ LL ++ ++ D K+P+ A + + L QD+ Sbjct: 422 RQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDI 469
>ASB16_HUMAN (Q96NS5) Ankyrin repeat and SOCS box protein 16 (ASB-16)| Length = 453 Score = 59.3 bits (142), Expect = 1e-08 Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 1/104 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD-AL 358 +H + + ++ L GA + EG LH L+CA++LLEAGA V+ A Sbjct: 147 LHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAA 206 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 +++ TPLH AA G ++ V L L+HGA V L+ G+T + A Sbjct: 207 GESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAA 250 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/96 (36%), Positives = 46/96 (47%), Gaps = 1/96 (1%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA D V GR ALH AC + C +LL GA + L + TPLH +C Sbjct: 134 GAELDAR-VGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCA 192 Query: 297 DLLLKHGAAVMLQNLDG-KTPIEVAKLNSQDEVVKL 193 LLL+ GA V L + +TP+ VA ++ V L Sbjct: 193 KLLLEAGATVNLAAGESQETPLHVAAARGLEQHVAL 228 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/117 (32%), Positives = 55/117 (47%), Gaps = 8/117 (6%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE--------LKCAEILLEA 379 +H A+ G + + L+ GA+ +G AL+ AC E A LLEA Sbjct: 214 LHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEA 273 Query: 378 GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD 208 GA A + ++TPLH A G +LLL++GA + N G TP++ A QD Sbjct: 274 GADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQD 330 Score = 38.9 bits (89), Expect = 0.015 Identities = 26/82 (31%), Positives = 37/82 (45%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 L A G CA L+ GA +DA + LH A + +CV LLL GA + Sbjct: 115 LAIATARGYTDCARHLIRQGAELDARVGGR-AALHEACARAQFDCVRLLLTFGAKANVLT 173 Query: 255 LDGKTPIEVAKLNSQDEVVKLL 190 +G TP+ + + + KLL Sbjct: 174 EEGTTPLHLCTIPESLQCAKLL 195
>LIN12_CAEEL (P14585) Protein lin-12 precursor (Abnormal cell lineage protein 12)| Length = 1429 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/108 (32%), Positives = 57/108 (52%), Gaps = 1/108 (0%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILL-EAGAAVDALDKNKNTPLHY 328 +G K DG A KD E +GR ALH+A + + L+ E G+ D D++ TP+ Sbjct: 1188 KGAKVDYDGAARKDSEKYKGRTALHYAAQVSNMPIVKYLVGEKGSNKDKQDEDGKTPIML 1247 Query: 327 AAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 AA GR E V L++ GA+V + T ++A+ N+ +V + ++ Sbjct: 1248 AAQEGRIEVVMYLIQQGASVEAVDATDHTARQLAQANNHHNIVDIFDR 1295 Score = 40.0 bits (92), Expect = 0.007 Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKAL-DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 +H A V + +K + + G+NKD++D +G+ + A G ++ L++ GA+V+A+ Sbjct: 1211 LHYAAQVSNMPIVKYLVGEKGSNKDKQDEDGKTPIMLAAQEGRIEVVMYLIQQGASVEAV 1270 Query: 357 DKNKNTPLHYAAGYGRKECVDL 292 D +T A VD+ Sbjct: 1271 DATDHTARQLAQANNHHNIVDI 1292 Score = 35.0 bits (79), Expect = 0.21 Identities = 21/61 (34%), Positives = 33/61 (54%) Frame = -3 Query: 399 AEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKL 220 A+ + AGA V+A+D ++NTPL A R+ V L+K GA + N ++ + A Sbjct: 1077 AKECIAAGADVNAMDCDENTPLMLAVLARRRRLVAYLMKAGADPTIYNKSERSALHQAAA 1136 Query: 219 N 217 N Sbjct: 1137 N 1137
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 59.3 bits (142), Expect = 1e-08 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + S GD + + L+ GA+ D GR + C Y +L+ G+A D L Sbjct: 156 LHISCSNGDNDIVAMLLNAGADASAIDANGRTPVQVVCFYNHASTLHLLISKGSA-DFLK 214 Query: 354 KNKNT---PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 ++ N PLH AA G ECV +LL A++ ++LDG TP ++A VV+ + Sbjct: 215 RSPNNGWVPLHEAAMRGSLECVKVLLSFNASMYPRSLDGDTPRDLALQYENYNVVEFFD 273 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 2/96 (2%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + + G ALH +C G+ +LL AGA A+D N TP+ Y + L Sbjct: 144 NVNARSISGLTALHISCSNGDNDIVAMLLNAGADASAIDANGRTPVQVVCFYNHASTLHL 203 Query: 291 LLKHGAAVMLQNL--DGKTPIEVAKLNSQDEVVKLL 190 L+ G+A L+ +G P+ A + E VK+L Sbjct: 204 LISKGSADFLKRSPNNGWVPLHEAAMRGSLECVKVL 239
>MIB2_RAT (Q68LP1) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (RBSC-skeletrophin/dystrophin-like polypeptide) Length = 971 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/87 (41%), Positives = 47/87 (54%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +GR AL A G+++ +LL+A A+VD LD+ NT LHY A + E LLL G Sbjct: 478 QGRTALQVAAYLGQVELVRLLLQARASVDLLDEEGNTALHYTAMGNQPEATRLLLSAGCG 537 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V QN T + VA EVVK+L Sbjct: 538 VDAQNGTRSTALHVAVQRGFLEVVKIL 564 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/99 (34%), Positives = 49/99 (49%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A +G E ++ L A+ D D EG ALH+ + + +LL AG VDA + ++ Sbjct: 487 AYLGQVELVRLLLQARASVDLLDEEGNTALHYTAMGNQPEATRLLLSAGCGVDAQNGTRS 546 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 T LH A G E V +L +HG V L + TP+ A Sbjct: 547 TALHVAVQRGFLEVVKILCEHGCDVNLPDAHADTPLHSA 585 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 3/108 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H TA E + L G D ++ ALH A G L+ +IL E G V+ D Sbjct: 516 LHYTAMGNQPEATRLLLSAGCGVDAQNGTRSTALHVAVQRGFLEVVKILCEHGCDVNLPD 575 Query: 354 KNKNTPLHYA--AGYGRKECVDLLLK-HGAAVMLQNLDGKTPIEVAKL 220 + +TPLH A AG G V++L + G V N G T + A L Sbjct: 576 AHADTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASL 623
>INVSB_XENLA (Q71S21) Inversin-B| Length = 1002 Score = 59.3 bits (142), Expect = 1e-08 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G+A + ++ N D +D EGR L A G + C E+L+E A + Sbjct: 421 SPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNI 480 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGA-AVMLQNLDGK-TPIEVAKLNSQDEVVKLL 190 DKN T LH++ G + V LLL + A ++N + + TP++ A L EV++ + Sbjct: 481 QDKNGRTALHWSCNNGYLDAVKLLLGYNAFPNQMENTEERYTPLDYALLGGHQEVIQFM 539 Score = 59.3 bits (142), Expect = 1e-08 Identities = 35/89 (39%), Positives = 48/89 (53%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A G++ ILLE A DA+D K+TPL A G +E + L+K G Sbjct: 350 DKYGGTALHAASLSGQITTVRILLENRAQADAVDVMKHTPLFRACEMGHREVIATLIKGG 409 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A V L + DG++P+ A L V ++L Sbjct: 410 AKVHLVDKDGRSPLHWAALGGNANVCQIL 438 Score = 56.6 bits (135), Expect = 7e-08 Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 2/105 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--AGAAVDA 361 +H A G+ LK L A+ D+ ALH + + + +C +LL+ VDA Sbjct: 81 LHLAAQTGNHRLLKLLLSRKADCTHRDLCDITALHLSTRHQDTQCLVLLLKYTPPGQVDA 140 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 D+ K T LH++A Y R + V LL++HG+ + + + +GK P+ A Sbjct: 141 QDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWA 185 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/109 (32%), Positives = 55/109 (50%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G E + + GGA D +GR LH+A G +IL+E DA D TP Sbjct: 396 MGHREVIATLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTP 455 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA G C+++L+++ A +Q+ +G+T + + N + VKLL Sbjct: 456 LQCAAYGGYIGCMEVLMENKADPNIQDKNGRTALHWSCNNGYLDAVKLL 504 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/103 (28%), Positives = 50/103 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G ++ L+ A D DV L AC G + L++ GA V +D Sbjct: 357 LHAASLSGQITTVRILLENRAQADAVDVMKHTPLFRACEMGHREVIATLIKGGAKVHLVD 416 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 K+ +PLH+AA G +L+++ Q+ +G+TP++ A Sbjct: 417 KDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCA 459 Score = 46.2 bits (108), Expect = 9e-05 Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 2/73 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYG 313 ++ A+ + +D GR ALH++C G L ++LL A + ++ + TPL YA G Sbjct: 472 MENKADPNIQDKNGRTALHWSCNNGYLDAVKLLLGYNAFPNQMENTEERYTPLDYALLGG 531 Query: 312 RKECVDLLLKHGA 274 +E + +L+HGA Sbjct: 532 HQEVIQFMLEHGA 544 Score = 43.9 bits (102), Expect = 5e-04 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKE------ 304 D +D + ALH++ Y + +L+ G+ + D PLH+AAG+ E Sbjct: 139 DAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVR 198 Query: 303 CVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 C+ + + Q+ +G+TP+ +A + EVV+LL Sbjct: 199 CLFEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLL 236 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/92 (31%), Positives = 45/92 (48%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D+ED GR L ++ CAE LL+ GA V+ D++ T LH AA G + LLL Sbjct: 38 DQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRPDRSGRTALHLAAQTGNHRLLKLLL 97 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A ++L T + ++ + + + LL Sbjct: 98 SRKADCTHRDLCDITALHLSTRHQDTQCLVLL 129 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA-LDKNKNTPLHYAAGYGRKEC 301 G N D R LH+A G A +LLE + + D TPLHYAA + Sbjct: 241 GCNVAPYDNLFRTPLHWAALLGHTPIAHLLLERNNSPNIPSDSQGATPLHYAAQGNCPDT 300 Query: 300 VDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V +LL H + +L+G+T + A DEVV+ + Sbjct: 301 VRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTM 337 Score = 42.0 bits (97), Expect = 0.002 Identities = 21/68 (30%), Positives = 35/68 (51%) Frame = -3 Query: 393 ILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 ++ + +D D+ TPL Y+ R+ C + LLKHGA V + G+T + +A Sbjct: 29 LIASSPQVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRPDRSGRTALHLAAQTG 88 Query: 213 QDEVVKLL 190 ++KLL Sbjct: 89 NHRLLKLL 96 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 7/122 (5%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCA---EILLEAGAAVD 364 +H +A + ++ + G+N D EG+ LH+A G+ + + A L EA Sbjct: 149 LHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVRCLFEAAPTES 208 Query: 363 AL---DKNKNTPLHYAAGYGRKECVDLLLKH-GAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 L D TPLH A G G +E V LL + G V + +TP+ A L + Sbjct: 209 LLNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAH 268 Query: 195 LL 190 LL Sbjct: 269 LL 270 Score = 35.4 bits (80), Expect = 0.16 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 2/91 (2%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D +G LH+A +LL + D D T L +AAG G E V +L+ Sbjct: 282 DSQGATPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTMLELN 341 Query: 276 AAVMLQNLD--GKTPIEVAKLNSQDEVVKLL 190 + + D G T + A L+ Q V++L Sbjct: 342 PKLEVNRTDKYGGTALHAASLSGQITTVRIL 372
>INVSA_XENLA (Q71S22) Inversin-A| Length = 1007 Score = 59.3 bits (142), Expect = 1e-08 Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G+A + ++ N D +D EGR L A G + C E+L+E A + Sbjct: 421 SPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNI 480 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGA-AVMLQNLDGK-TPIEVAKLNSQDEVVKLL 190 DKN T LH++ G + V LLL + A ++N + + TP++ A L EV++ + Sbjct: 481 QDKNGRTALHWSCNNGYLDAVKLLLGYSAFPNQMENTEERYTPLDYALLGGHQEVIQFM 539 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/99 (36%), Positives = 50/99 (50%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 LD + D G ALH A G++ ILLE VDA+D K+T L A G + Sbjct: 340 LDPELEVNRTDKYGGTALHAASLSGQITTVRILLENRVQVDAVDVMKHTALFRACEMGHR 399 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 E + L+K GA V L + DG++P+ A L V ++L Sbjct: 400 EVISTLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQIL 438 Score = 56.2 bits (134), Expect = 9e-08 Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 2/105 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--AGAAVDA 361 +H A G+ LK L A+ D+ A+H + + + +C ++L+ VDA Sbjct: 81 LHLAAQTGNHRLLKLLLSRKADCTHRDLRDITAVHLSTRHQDTRCLALILKYTPPGQVDA 140 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 D+ K T LH++A Y R V LL++HG+ + + + +GK P+ A Sbjct: 141 QDQRKQTALHWSAYYNRPRHVRLLVRHGSNIGIPDTEGKIPLHWA 185 Score = 54.7 bits (130), Expect = 3e-07 Identities = 35/109 (32%), Positives = 55/109 (50%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G E + + GGA D +GR LH+A G +IL+E DA D TP Sbjct: 396 MGHREVISTLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTP 455 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA G C+++L+++ A +Q+ +G+T + + N + VKLL Sbjct: 456 LQCAAYGGYIGCMEVLMENKADPNIQDKNGRTALHWSCNNGYLDAVKLL 504 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/103 (28%), Positives = 50/103 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G ++ L+ D DV AL AC G + L++ GA V +D Sbjct: 357 LHAASLSGQITTVRILLENRVQVDAVDVMKHTALFRACEMGHREVISTLIKGGAKVHLVD 416 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 K+ +PLH+AA G +L+++ Q+ +G+TP++ A Sbjct: 417 KDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCA 459 Score = 46.2 bits (108), Expect = 9e-05 Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 2/73 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYG 313 ++ A+ + +D GR ALH++C G L ++LL A + ++ + TPL YA G Sbjct: 472 MENKADPNIQDKNGRTALHWSCNNGYLDAVKLLLGYSAFPNQMENTEERYTPLDYALLGG 531 Query: 312 RKECVDLLLKHGA 274 +E + +L+HGA Sbjct: 532 HQEVIQFMLEHGA 544 Score = 45.4 bits (106), Expect = 2e-04 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 6/98 (6%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC---VD 295 D +D + ALH++ Y + +L+ G+ + D PLH+AAG+ E V Sbjct: 139 DAQDQRKQTALHWSAYYNRPRHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVR 198 Query: 294 LLLKHGAAVML---QNLDGKTPIEVAKLNSQDEVVKLL 190 LL+ L Q+ +G+TP+ +A + EVV+LL Sbjct: 199 CLLEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLL 236 Score = 44.3 bits (103), Expect = 3e-04 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANK-DEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 S V A GD L K + D+ED GR L ++ CAE LL+ GA V+ Sbjct: 12 SPVQAAAVTGDKTTLLKLIASSPEVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAQVN 71 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D++ T LH AA G + LLL A ++L T + ++ + + L+ Sbjct: 72 HPDRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRDLRDITAVHLSTRHQDTRCLALI 129 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 2/101 (1%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA-LDKNKNTPLHYAAGYGRKEC 301 G N D R LH+A G A +LLE + + D TPLHYAA + Sbjct: 241 GCNVAPYDNLFRTPLHWAALLGYTPIAHLLLETNNSPNIPSDSQGATPLHYAAQGNCPDT 300 Query: 300 VDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQD 181 V +LL H + +L+G+T A DEVV+ +LE D Sbjct: 301 VRVLLSHISVRDEADLEGRTAFMWAAGKGSDEVVRTMLELD 341 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/115 (33%), Positives = 52/115 (45%), Gaps = 7/115 (6%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCA---EILLEAGAAVDAL---DKNKNTPLHYAAGY 316 G+N D EG+ LH+A G+ + + A LLEA L D TPLH A G Sbjct: 168 GSNIGIPDTEGKIPLHWAAGHKDPEAALTVRCLLEAAPTESLLNWQDYEGRTPLHLAVGD 227 Query: 315 GRKECVDLLLKH-GAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSD 154 G +E V LL + G V + +TP+ A L + LL + + PSD Sbjct: 228 GNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGYTPIAHLLLETNNSPNIPSD 282
>ACBD6_XENTR (Q66JD7) Acyl-CoA-binding domain-containing protein 6| Length = 286 Score = 59.3 bits (142), Expect = 1e-08 Identities = 34/84 (40%), Positives = 44/84 (52%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + + D EGR LH+AC G + +LL A ++ D TPLHYA+ + Sbjct: 172 GAIDVNVADDEGRCLLHWACDRGHTQLVSVLLFHNAHINMQDSEGQTPLHYASACEFPDI 231 Query: 300 VDLLLKHGAAVMLQNLDGKTPIEV 229 VDLLL HGA L + DG P EV Sbjct: 232 VDLLLDHGADPSLVDNDGFQPHEV 255 Score = 38.5 bits (88), Expect = 0.019 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%) Frame = -3 Query: 387 LEAGAA-VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 L GA V+ D LH+A G + V +LL H A + +Q+ +G+TP+ A Sbjct: 169 LSTGAIDVNVADDEGRCLLHWACDRGHTQLVSVLLFHNAHINMQDSEGQTPLHYASACEF 228 Query: 210 DEVVKLLEQDVFL*SKPSDPVLID 139 ++V LL +DP L+D Sbjct: 229 PDIVDLLL------DHGADPSLVD 246
>MIB1_XENLA (Q6GNY1) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) Length = 1011 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/108 (32%), Positives = 54/108 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + LK L + + ED +G RA+H A E E+L GA ++A +K + TPL Sbjct: 475 GHVDILKLLLKHSVDVEAEDKDGDRAVHHAAFGDEGTVIEVLQRGGADLNARNKRRQTPL 534 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 H A G + V LL LQ+ +G TP+ A +D+++ +L Sbjct: 535 HIAVNKGHLQVVKKLLDFSCHPSLQDSEGDTPLHDAISKKRDDILAVL 582 Score = 46.2 bits (108), Expect = 9e-05 Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDALDKNKNTPLHYAAGYGRKECVDLL 289 DE+ +G ALH A ++ AE+L+ G+A +D + N+ T LH A + V LL Sbjct: 626 DEKKDDGYTALHLAALNNHVEVAELLVHQGSANLDIQNVNQQTALHLAVERQHTQIVRLL 685 Query: 288 LKHGAAVMLQNLDGKTPIEVA 226 ++ A + +Q+ DG TP+ A Sbjct: 686 VRAEAKLDIQDKDGDTPLHEA 706 Score = 46.2 bits (108), Expect = 9e-05 Identities = 35/134 (26%), Positives = 59/134 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 VH+ A + ++ GGA+ + + + LH A G L+ + LL+ D Sbjct: 501 VHHAAFGDEGTVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKKLLDFSCHPSLQD 560 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 +TPLH A R + + +LL+ GA V + N +G + A L +++L Sbjct: 561 SEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL---- 616 Query: 174 L*SKPSDPVLIDPK 133 SK P ++D K Sbjct: 617 --SKLPRPWIVDEK 628 Score = 39.3 bits (90), Expect = 0.011 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Frame = -3 Query: 507 AEGLKKALDGGANKDEEDVEGRRALHFACGY----GELKCAEILLEAGAAVDALDKNKNT 340 A G +D + + DV G+ A H A G + ++LL+ V+A DK+ + Sbjct: 440 ANGDVAKVDDLLKRQDVDVNGQCAGHTAMQAASQNGHVDILKLLLKHSVDVEAEDKDGDR 499 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +H+AA +++L + GA + +N +TP+ +A +VVK L Sbjct: 500 AVHHAAFGDEGTVIEVLQRGGADLNARNKRRQTPLHIAVNKGHLQVVKKL 549 Score = 38.1 bits (87), Expect = 0.025 Identities = 20/52 (38%), Positives = 29/52 (55%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 G AN D ++V + ALH A + +L+ A A +D DK+ +TPLH A Sbjct: 655 GSANLDIQNVNQQTALHLAVERQHTQIVRLLVRAEAKLDIQDKDGDTPLHEA 706
>MIB1_MOUSE (Q80SY4) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) (DAPK-interacting protein 1) (DIP-1) Length = 1006 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/108 (32%), Positives = 54/108 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + LK L + + ED +G RA+H A E E+L A ++A +K + TPL Sbjct: 475 GHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPL 534 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 H A G + V LL G LQ+ +G TP+ A +D+++ +L Sbjct: 535 HIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAG-AAVDALDKNKNTPLHYAAGYGRKECVDLL 289 DE+ +G ALH A ++ AE+L+ G A +D + N+ T LH A + V LL Sbjct: 626 DEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLL 685 Query: 288 LKHGAAVMLQNLDGKTPIEVA 226 ++ GA + +Q+ DG TP+ A Sbjct: 686 VRAGAKLDIQDKDGDTPLHEA 706 Score = 46.6 bits (109), Expect = 7e-05 Identities = 35/134 (26%), Positives = 59/134 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 VH+ A + ++ G A+ + + + LH A G L+ + LL+ G D Sbjct: 501 VHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD 560 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 +TPLH A R + + +LL+ GA V + N +G + A L +++L Sbjct: 561 SEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL---- 616 Query: 174 L*SKPSDPVLIDPK 133 SK P ++D K Sbjct: 617 --SKLPRPWIVDEK 628 Score = 41.2 bits (95), Expect = 0.003 Identities = 21/52 (40%), Positives = 30/52 (57%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 G AN D ++V + ALH A + +L+ AGA +D DK+ +TPLH A Sbjct: 655 GNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEA 706 Score = 37.4 bits (85), Expect = 0.042 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = -3 Query: 504 EGLKKALDGGANKDEE-----DVE------GRRALHFACGYGELKCAEILLEAGAAVDAL 358 E +K A +G K E+ DV+ G A+ A G + ++LL+ V+A Sbjct: 434 ELVKAAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAE 493 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK+ + +H+AA +++L + A + +N +TP+ +A +VVK L Sbjct: 494 DKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTL 549
>MIB1_HUMAN (Q86YT6) Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb| homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2) Length = 1006 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/108 (32%), Positives = 54/108 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + LK L + + ED +G RA+H A E E+L A ++A +K + TPL Sbjct: 475 GHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPL 534 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 H A G + V LL G LQ+ +G TP+ A +D+++ +L Sbjct: 535 HIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAG-AAVDALDKNKNTPLHYAAGYGRKECVDLL 289 DE+ +G ALH A ++ AE+L+ G A +D + N+ T LH A + V LL Sbjct: 626 DEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLL 685 Query: 288 LKHGAAVMLQNLDGKTPIEVA 226 ++ GA + +Q+ DG TP+ A Sbjct: 686 VRAGAKLDIQDKDGDTPLHEA 706 Score = 46.6 bits (109), Expect = 7e-05 Identities = 35/134 (26%), Positives = 59/134 (44%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 VH+ A + ++ G A+ + + + LH A G L+ + LL+ G D Sbjct: 501 VHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQD 560 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 +TPLH A R + + +LL+ GA V + N +G + A L +++L Sbjct: 561 SEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLL---- 616 Query: 174 L*SKPSDPVLIDPK 133 SK P ++D K Sbjct: 617 --SKLPRPWIVDEK 628 Score = 41.2 bits (95), Expect = 0.003 Identities = 21/52 (40%), Positives = 30/52 (57%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 G AN D ++V + ALH A + +L+ AGA +D DK+ +TPLH A Sbjct: 655 GNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEA 706 Score = 37.4 bits (85), Expect = 0.042 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Frame = -3 Query: 504 EGLKKALDGGANKDEE-----DVE------GRRALHFACGYGELKCAEILLEAGAAVDAL 358 E +K A +G K E+ DV+ G A+ A G + ++LL+ V+A Sbjct: 434 ELVKAAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAE 493 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK+ + +H+AA +++L + A + +N +TP+ +A +VVK L Sbjct: 494 DKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTL 549
>ASB3_HUMAN (Q9Y575) Ankyrin repeat and SOCS box protein 3 (ASB-3)| Length = 518 Score = 58.9 bits (141), Expect = 1e-08 Identities = 43/117 (36%), Positives = 61/117 (52%), Gaps = 2/117 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + +AE +K L GANK+ +D G L A YG+L+ IL+ +GA V+ Sbjct: 150 LHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQA 209 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ-NLDG-KTPIEVAKLNSQDEVVKLL 190 +K TPL AA G +CV+LLL GA L N D + PI A +++ LL Sbjct: 210 LDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLL 266 Score = 54.7 bits (130), Expect = 3e-07 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 4/119 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDE---EDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 +H A E L+ ++ ++++ + EG ALH A G K +ILLEAGA + Sbjct: 47 IHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPN 106 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVM-LQNLDGKTPIEVAKLNSQDEVVKLL 190 A + TPL A G+ + + LLL+HGA V ++ G + A E++KLL Sbjct: 107 ATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLL 165 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 1/109 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKD-EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G + L+ L GAN + + G +LH A + ++LL GA + D TP Sbjct: 123 GQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITP 182 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L AA YG+ E + +L+ GA V Q LD TP+ +A + V+LL Sbjct: 183 LFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELL 231 Score = 44.7 bits (104), Expect = 3e-04 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 2/113 (1%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL--DKN 349 A G E L + GAN + + ++ L A G KC E+LL +GA D + + Sbjct: 187 AQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDS 246 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 P+H AA G + +DLL+ L+ +P+ A ++ +++L Sbjct: 247 WQLPIHAAAQMGHTKILDLLIPLTNRACDTGLNKVSPVYSAVFGGHEDCLEIL 299 Score = 35.0 bits (79), Expect = 0.21 Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 3/78 (3%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA---VMLQNLDGK 244 G +K LL+ G +VD D P+H AA + EC+ +L+ ++ + ++ +G Sbjct: 21 GNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGF 80 Query: 243 TPIEVAKLNSQDEVVKLL 190 + +A ++V++L Sbjct: 81 CALHLAASQGHWKIVQIL 98
>ASB5_RABIT (Q862Z2) Ankyrin repeat and SOCS box protein 5 (ASB-5)| Length = 329 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/95 (36%), Positives = 49/95 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H AS G L+ L G N + ++ LH AC + CA LLEAGA V+A Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTIDHITPLHEACLGDHVACARTLLEAGANVNA 131 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 + + TPL A G C +LLL++GA L++ Sbjct: 132 ITIDGVTPLFNACSQGSTSCTELLLEYGAKAQLES 166 Score = 52.4 bits (124), Expect = 1e-06 Identities = 39/116 (33%), Positives = 56/116 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S H AS G E L + G + D++ L+ AC + C LL AGA V Sbjct: 170 SPTHEAASKGHHEFLDLLISWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK 229 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 K +TPLH AA E V+LL++ GA + +N + P++VA +S E + L Sbjct: 230 -GKYWDTPLHAAAQQSSTEIVNLLIEFGADINAKNTELLRPVDVATTSSMVERILL 284 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/81 (33%), Positives = 35/81 (43%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + + R LH A G L LL G V+A+ + TPLH A C Sbjct: 60 GVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTIDHITPLHEACLGDHVACA 119 Query: 297 DLLLKHGAAVMLQNLDGKTPI 235 LL+ GA V +DG TP+ Sbjct: 120 RTLLEAGANVNAITIDGVTPL 140
>FANK1_MOUSE (Q9DAM9) Fibronectin type 3 and ankyrin repeat domains 1 protein| (Germ cell-specific gene 1 protein) (GSG1) Length = 344 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/98 (35%), Positives = 58/98 (59%), Gaps = 2/98 (2%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-TPL-HYAAGYGRKE 304 GA+ + D+ G ALH+A G + +++ G VD +D TPL +A G ++ Sbjct: 200 GASWEARDLGGCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQK 259 Query: 303 CVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LL++ GA V +++ DGKTP+ VA LN+ +++V+LL Sbjct: 260 VASLLIEAGADVNIKDKDGKTPLMVAVLNNHEQLVQLL 297 Score = 52.8 bits (125), Expect = 1e-06 Identities = 30/77 (38%), Positives = 45/77 (58%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G K A +L+EAGA V+ DK+ TPL A ++ V LLL GA ++N GK + Sbjct: 256 GSQKVASLLIEAGADVNIKDKDGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVL 315 Query: 234 EVAKLNSQDEVVKLLEQ 184 E+A++ + V+ LLE+ Sbjct: 316 EMARVFDRQNVLSLLEE 332
>OSBL1_HUMAN (Q9BXW6) Oxysterol-binding protein-related protein 1 (OSBP-related| protein 1) (ORP-1) Length = 950 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/91 (40%), Positives = 52/91 (57%), Gaps = 3/91 (3%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G LH AC +G + + LL+AGA V+ L+ +TPLH AA GRKE V LLL++ A Sbjct: 48 GWTPLHLACYFGHRQVVQDLLKAGAEVNVLNDMGDTPLHRAAFTGRKELVMLLLEYNADT 107 Query: 267 MLQNLDGKTPIEVA---KLNSQDEVVKLLEQ 184 + N G+T EV ++ S E V+ +Q Sbjct: 108 TIVNGSGQTAKEVTHAEEIRSMLEAVERTQQ 138 Score = 37.4 bits (85), Expect = 0.042 Identities = 19/49 (38%), Positives = 30/49 (61%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 V+ D+ NTPLH AA K+C LL+ GA L+N + + P+++A+ Sbjct: 169 VNCSDQLGNTPLHCAAYRAHKQCALKLLRSGADPNLKNKNDQKPLDLAQ 217
>CDN2C_MOUSE (Q60772) Cyclin-dependent kinase 6 inhibitor (p18-INK6)| (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c) Length = 168 Score = 58.9 bits (141), Expect = 1e-08 Identities = 39/111 (35%), Positives = 58/111 (52%), Gaps = 1/111 (0%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G+ E ++ L GAN + +D G +H A G L + LLE A V+ D N P Sbjct: 47 LGNPEIARRLLLRGANPNLKDGTGFAVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLP 106 Query: 336 LHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 LH AA G V+ L+KH A V +N G T ++A+ ++EV+ L+E Sbjct: 107 LHLAAKEGHLPVVEFLMKHTACNVGHRNHKGDTAFDLARFYGRNEVISLME 157 Score = 40.4 bits (93), Expect = 0.005 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VD 364 +++H+ A G + ++ L+ A+ + ED EG LH A G L E L++ A V Sbjct: 72 AVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLPLHLAAKEGHLPVVEFLMKHTACNVG 131 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 + +T A YGR E + L+ +G Sbjct: 132 HRNHKGDTAFDLARFYGRNEVISLMEANG 160
>V014_FOWPV (Q9J5I7) Putative ankyrin repeat protein FPV014| Length = 437 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/115 (31%), Positives = 61/115 (53%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +++ A+ G+ E K +D GA + + +H A G + LL GA D D Sbjct: 136 INDAAANGNLEICKLLIDAGARINSRSMGSVYTIHHAIRSGNYELVVELLSRGALPDVED 195 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + LH+A G + V LL+HGA+V +Q+ G+TP+ +A S+ ++VK+L Sbjct: 196 ELSFSSLHHAVMEGSADMVLTLLEHGASVDVQDFCGRTPLFLAANASELDIVKVL 250 Score = 47.4 bits (111), Expect = 4e-05 Identities = 38/117 (32%), Positives = 54/117 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H+ G+ E + + L GA D ED +LH A G LLE GA+VD D Sbjct: 169 IHHAIRSGNYELVVELLSRGALPDVEDELSFSSLHHAVMEGSADMVLTLLEHGASVDVQD 228 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 TPL AA + V +LL A + + TP+ V LNS D +++ +Q Sbjct: 229 FCGRTPLFLAANASELDIVKVLLDFWADTSVSS-GRNTPLSVCDLNS-DTGIEIAKQ 283 Score = 32.7 bits (73), Expect = 1.0 Identities = 34/119 (28%), Positives = 49/119 (41%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++H G+ E + L GAN D ALH A +L+E D Sbjct: 35 SLLHCAVENGNTEIARILLLEGANPDLYTESTPTALHRAVILRHYDIVNLLMEFNVDPDN 94 Query: 360 LDKNKN-TPLHYAAGYGRKECVDLLLKHGA-AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + +++ TPL YA + LL +GA A + + PI A N E+ KLL Sbjct: 95 YENHESRTPLEYAVKLNDVKMTKTLLDYGADAEDIYRFN--CPINDAAANGNLEICKLL 151
>SHAN3_RAT (Q9JLU4) SH3 and multiple ankyrin repeat domains 3 (Shank3)| (Proline-rich synapse associated protein 2) (ProSAP2) (SPANK-2) Length = 1815 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRAL-HFACGYGELKCAEILLEAGAAVDAL 358 VH +A L LD GA+ D +D G L H A G G+ C E+LL A + Sbjct: 262 VHCATRQRNAGALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGTT 321 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D+N +H A +G + ++ LL +GA + QN G T + + L +Q+ ++L Sbjct: 322 DENGWQEIHQACRFGHVQHLEHLLFYGANMGAQNASGNTALHICALYNQESCARVL 377 Score = 45.4 bits (106), Expect = 2e-04 Identities = 25/85 (29%), Positives = 36/85 (42%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H G + L+ L GAN ++ G ALH Y + CA +LL GA D + Sbjct: 329 IHQACRFGHVQHLEHLLFYGANMGAQNASGNTALHICALYNQESCARVLLFRGANKDVRN 388 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKH 280 N T A G E +++ H Sbjct: 389 YNSQTAFQVAIIAGNFELAEVIKTH 413
>NOTC4_HUMAN (Q99466) Neurogenic locus notch homolog protein 4 precursor (Notch 4)| (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain] Length = 2003 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/96 (38%), Positives = 50/96 (52%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ D G+ ALH+A + A LL+AGA DA D + TPL AA G E Sbjct: 1725 ADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQ 1784 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 LLL GAA L++ G P +VA + +++ LLE Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLLE 1820 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 2/113 (1%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDV-EGRRALHFACGYGELKCAEILLEAGAAVDALDKNK 346 A +G E + LDGGA V G LH A + A LLEAGA + D+ Sbjct: 1608 AWLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAG 1667 Query: 345 NTPLHYAAGYGRKECVDLLLK-HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPLH A +E LLL+ AV + DG TP+ +A + +++V+ L Sbjct: 1668 RTPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEEL 1720 Score = 42.7 bits (99), Expect = 0.001 Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAG-AAVDAL 358 +H A ++ L+ GAN ++ D GR LH A + ++LL + AVDA Sbjct: 1638 LHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDAR 1697 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 ++ TPL AA ++ V+ L+ A V ++ GKT + A +N+ LL+ Sbjct: 1698 TEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQ 1755 Score = 37.7 bits (86), Expect = 0.032 Identities = 22/70 (31%), Positives = 35/70 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+V +A + L GA+KD +D + L A G ++ A++LL GAA + D Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRD 1797 Query: 354 KNKNTPLHYA 325 + P A Sbjct: 1798 QAGLAPADVA 1807
>IKBE_MOUSE (O54910) NF-kappa-B inhibitor epsilon (NF-kappa-BIE)| (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E) Length = 364 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%) Frame = -3 Query: 486 LDGGANKD-EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 L GA+ D +E G+ ALH A E + LL+AGA VDA N TPLH AAG G Sbjct: 254 LQNGADIDVQEGTSGKTALHLAVETQERSLVQFLLQAGARVDARMLNGCTPLHLAAGRGL 313 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 L + GA +L N++ +TP ++A+ Sbjct: 314 NSISSTLCEAGADSLLLNVEDETPQDLAE 342 Score = 38.1 bits (87), Expect = 0.025 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 11/109 (10%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLE--------AGAAVDALDKNKN--TPLHY 328 GA++ +D G ALH AC L CA LLE +D KN LH Sbjct: 181 GASRILQDQHGDTALHVACRRQNLACACCLLEEQPEPGRQLSHPLDLQLKNWQGLACLHI 240 Query: 327 AAGYGRKECVDLLLKHGAAVMLQ-NLDGKTPIEVAKLNSQDEVVKLLEQ 184 A + ++LLL++GA + +Q GKT + +A + +V+ L Q Sbjct: 241 ATLQRNQPLIELLLQNGADIDVQEGTSGKTALHLAVETQERSLVQFLLQ 289
>MTPN_RAT (P62775) Myotrophin (V-1 protein) (Granule cell differentiation| protein) Length = 117 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/110 (34%), Positives = 57/110 (51%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD + +K + G + + GR+ LH+A G+L+ E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 A G CV LLL GA ++ DG T +E + ++ +K L Q Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEA----TDNQAIKALLQ 117
>MTPN_MOUSE (P62774) Myotrophin (V-1 protein) (Granule cell differentiation| protein) Length = 117 Score = 58.5 bits (140), Expect = 2e-08 Identities = 38/110 (34%), Positives = 57/110 (51%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD + +K + G + + GR+ LH+A G+L+ E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 A G CV LLL GA ++ DG T +E + ++ +K L Q Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEA----TDNQAIKALLQ 117
>ASB11_HUMAN (Q8WXH4) Ankyrin repeat and SOCS box protein 11 (ASB-11)| Length = 323 Score = 58.5 bits (140), Expect = 2e-08 Identities = 39/119 (32%), Positives = 58/119 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H G E ++ L N D E + L+ AC Y + C + LLE GA+VD Sbjct: 165 SPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDH 224 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + +TPLH AA E + LL +GA + +N GK+ +++A S E LL + Sbjct: 225 -GQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLLRE 282 Score = 54.7 bits (130), Expect = 3e-07 Identities = 38/117 (32%), Positives = 58/117 (49%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A+ G LK + G N + + +LH AC G + CA+ LLE GA V+ Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + TPL A G CV++LL+ GA L+ + +PI A E +++L Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGAKAQLE-VHLASPIHEAVKRGHRECMEIL 182 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/114 (35%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 528 NTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKN 349 N G A + L+ GA K + +V +H A G +C EILL +D Sbjct: 137 NACCSGSAACVNVLLEFGA-KAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQ 195 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAV-MLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A Y R +CV LL+ GA+V Q LD TP+ A S EV+ LL Sbjct: 196 LGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAAARQSNVEVIHLL 247
>AKR1_MORAP (Q9UVH3) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) (Fragment) Length = 559 Score = 58.5 bits (140), Expect = 2e-08 Identities = 30/81 (37%), Positives = 45/81 (55%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D D G +L +A G+ +ILL+ GA VD D+ TPLH+A G +EC+ +L Sbjct: 37 DTADTLGHTSLMWAAYQGDSLSVQILLKHGARVDTKDREGFTPLHWAVVKGNRECLSKIL 96 Query: 285 KHGAAVMLQNLDGKTPIEVAK 223 GA + + GKTP+++ K Sbjct: 97 MAGADIKAGDKSGKTPVDMIK 117 Score = 43.5 bits (101), Expect = 6e-04 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAA-VDALDKNKNTPLHYAAGYGRKECVDLLLK 283 +D +G ALH A LL AG VD D +T L +AA G V +LLK Sbjct: 5 QDSQGFNALHLATHSSNAMLVLYLLMAGEMPVDTADTLGHTSLMWAAYQGDSLSVQILLK 64 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDE 205 HGA V ++ +G TP+ A + E Sbjct: 65 HGARVDTKDREGFTPLHWAVVKGNRE 90 Score = 40.8 bits (94), Expect = 0.004 Identities = 23/60 (38%), Positives = 33/60 (55%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD+ ++ L GA D +D EG LH+A G +C +L AGA + A DK+ TP+ Sbjct: 54 GDSLSVQILLKHGARVDTKDREGFTPLHWAVVKGNRECLSKILMAGADIKAGDKSGKTPV 113
>AKR1_YARLI (Q6C520) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 702 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 1/112 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 + GA+ DV+G ALH A + LL G VD D N T LH+AA G Sbjct: 138 IQNGADPLRSDVQGYNALHLATHSSNVMLLVYLLHQGLPVDCQDPNGRTALHWAAYQGDA 197 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLN-SQDEVVKLLEQDVFL*SKPSD 154 VD+LL+ G+ V + + G P+ +N S++ + +L+E+ + +K SD Sbjct: 198 LSVDVLLRWGSDVKITDTQGFLPLHWGIVNGSRNSLARLIEEGSDMYAKSSD 249 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/101 (29%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L G D +D GR ALH+A G+ ++LL G+ V D PLH+ G + Sbjct: 171 LHQGLPVDCQDPNGRTALHWAAYQGDALSVDVLLRWGSDVKITDTQGFLPLHWGIVNGSR 230 Query: 306 ECVDLLLKHGAAVMLQNLDGKTP-IEVAKLNSQDEVVKLLE 187 + L++ G+ + ++ DGKTP + A++N+ ++ L+ Sbjct: 231 NSLARLIEEGSDMYAKSSDGKTPHVMAAEMNTTAQLEGALD 271 Score = 42.7 bits (99), Expect = 0.001 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 2/102 (1%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVE-GRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-T 340 G+ +K+ + G+ + E G ALH+A + + L+E GA VDA N T Sbjct: 61 GNTAEVKRLCESGSYSVLDTAEDGVTALHWAAVNNRISTCQYLVEQGAVVDAKGGQLNGT 120 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 PLH+A G V L+++GA + ++ G + +A +S Sbjct: 121 PLHWACRRGLVYIVHYLIQNGADPLRSDVQGYNALHLATHSS 162
>ASB5_HUMAN (Q8WWX0) Ankyrin repeat and SOCS box protein 5 (ASB-5)| Length = 329 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/95 (36%), Positives = 49/95 (51%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H AS G L+ L G N + ++ LH AC + CA LLEAGA V+A Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 + + TPL A G C +LLL++GA L++ Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLES 166 Score = 53.9 bits (128), Expect = 4e-07 Identities = 42/116 (36%), Positives = 56/116 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S H AS G E L + G + D+E L+ AC + C LL AGA V Sbjct: 170 SPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQK 229 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 K +TPLH AA E V+LLL+ GA + +N + PI+VA +S E + L Sbjct: 230 -GKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILL 284 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/81 (33%), Positives = 35/81 (43%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + + R LH A G L LL G V+A+ + TPLH A C Sbjct: 60 GVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACA 119 Query: 297 DLLLKHGAAVMLQNLDGKTPI 235 LL+ GA V +DG TP+ Sbjct: 120 RTLLEAGANVNAITIDGVTPL 140
>AKR1_DEBHA (Q6BP80) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 821 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/95 (37%), Positives = 52/95 (54%), Gaps = 1/95 (1%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 DE D R +LH+A G+L LL+ GA V +DKN PLH+A G K + +L Sbjct: 284 DESDNCDRTSLHWAAYQGDLLTINALLKFGADVSKIDKNLFIPLHWAFMKGYKTVLKVLA 343 Query: 285 KHGAAVMLQNLDGKTPIEVAK-LNSQDEVVKLLEQ 184 G+ + +N GK EVAK +N D +K+L++ Sbjct: 344 GAGSNIFAKNDQGKDSFEVAKDMNCYDTWIKVLKE 378
>PYX_DROME (Q9W0T5) Transient receptor potential channel pyrexia| Length = 956 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/89 (40%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = -3 Query: 453 VEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 +E R ALH+A + C EILL+ GA + TPLH A+ G +CV LLL H A Sbjct: 197 IEKRSALHYAIDVNAVDCVEILLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNA 256 Query: 273 AVMLQNLDGK-TPIEVAKLNSQDEVVKLL 190 V Q +GK T + +A N E +LL Sbjct: 257 DVRSQFGEGKVTALHLAAENDYVECARLL 285 Score = 53.5 bits (127), Expect = 6e-07 Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H V + ++ L GA+ + V LH A G KC ++LL A V + Sbjct: 201 SALHYAIDVNAVDCVEILLKYGADPNTPQVYTETPLHTASAAGFAKCVQLLLSHNADVRS 260 Query: 360 -LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + K T LH AA EC LLL+H A V +N +TP+ +A L+ V LL Sbjct: 261 QFGEGKVTALHLAAENDYVECARLLLEHRAEVDCRNASHQTPLHLACLSQSIGTVDLL 318 Score = 52.8 bits (125), Expect = 1e-06 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGR-RALHFACGYGELKCAEILLEAGAAVDAL 358 +H ++ G A+ ++ L A+ + EG+ ALH A ++CA +LLE A VD Sbjct: 236 LHTASAAGFAKCVQLLLSHNADVRSQFGEGKVTALHLAAENDYVECARLLLEHRAEVDCR 295 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 + + TPLH A VDLL+ +GA V DG+T + A Sbjct: 296 NASHQTPLHLACLSQSIGTVDLLISYGANVNAVYRDGRTALHAA 339 Score = 45.4 bits (106), Expect = 2e-04 Identities = 38/113 (33%), Positives = 53/113 (46%), Gaps = 13/113 (11%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFAC--GYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKE 304 GAN + +GR ALH A L C LL+AGA V+ D TPLH AA Sbjct: 322 GANVNAVYRDGRTALHAAIVKQSRSLDCCNALLKAGADVNKADNYGYTPLHIAALNEFSS 381 Query: 303 CVDLLLKHGAAVMLQNLDG----------KTPIEVAKLNSQ-DEVVKLLEQDV 178 CV ++HGA + + DG +TP + KL + D +K +Q++ Sbjct: 382 CVYTFIEHGADITART-DGRVSALSFIVRRTPEIIPKLMQKLDSSIKANDQEI 433 Score = 44.7 bits (104), Expect = 3e-04 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-TPLHYAAGYGRKECV 298 A+ + D GR LHFAC A++LL+ GA + D K T LH AA EC+ Sbjct: 124 ADPNVADSRGRTPLHFACCRANAPIAKVLLDFGADPNRWDARKEVTSLHCAASSKSVECI 183 Query: 297 DLLLKHGAAV 268 LLL+ A++ Sbjct: 184 LLLLRRKASI 193
>MTPN_CHICK (Q91955) Myotrophin (V-1 protein) (Granule cell differentiation| protein) Length = 118 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/110 (34%), Positives = 56/110 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD + +K + G + + GR+ LH+A G+L+ E LL GA ++A DK+ TPL Sbjct: 13 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHNITPL 72 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 A G CV LLL GA ++ DG T E + ++ +K L Q Sbjct: 73 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEA----TDNQAIKTLLQ 118
>GABP3_MOUSE (P81069) GA-binding protein beta-2-1 chain (GABP-beta-2-1 subunit)| (GABPB2-1) Length = 414 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/119 (28%), Positives = 60/119 (50%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G + L G ++D R LH A G + E+L+ +GA V+A Sbjct: 40 SPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHVHIVELLVRSGADVNA 99 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 D + T LH+A + + V+LL+K+GA V + K+ ++A + E++ +L++ Sbjct: 100 KDMLQMTALHWATEHHHRLVVELLIKYGADVYAFSKFDKSAFDIAMEKNNTEILVMLQE 158 Score = 55.8 bits (133), Expect = 1e-07 Identities = 38/98 (38%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G LH A YG AE+LL AG + DA K TPLH AA G V+LL++ GA V Sbjct: 38 GTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGHVHIVELLVRSGADV 97 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLLEQ---DVFL*SK 163 +++ T + A + VV+LL + DV+ SK Sbjct: 98 NAKDMLQMTALHWATEHHHRLVVELLIKYGADVYAFSK 135 Score = 34.7 bits (78), Expect = 0.27 Identities = 20/67 (29%), Positives = 33/67 (49%) Frame = -3 Query: 390 LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 +L A A D +PLH AA YG ++LL+ G + + +TP+ +A + Sbjct: 24 ILMANGAPFTTDWLGTSPLHLAAQYGHYSTAEVLLRAGVSRDARTKVDRTPLHMAAADGH 83 Query: 210 DEVVKLL 190 +V+LL Sbjct: 84 VHIVELL 90
>V162_FOWPV (Q9J569) Putative ankyrin repeat protein FPV162| Length = 603 Score = 57.8 bits (138), Expect = 3e-08 Identities = 39/112 (34%), Positives = 58/112 (51%), Gaps = 3/112 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGY--GELKCAEILLEAGAAVDA 361 +H E KK LD GA+ + + + G+ LH A + IL+E GA V+A Sbjct: 96 LHYAVQENGLEATKKLLDLGADPNTKYMNGQTPLHCAAMVIPDGPELVRILVEYGANVNA 155 Query: 360 LDKNKNTPLHYAAGYGR-KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD 208 LD NTPL AA + ++ L++ GA V ++N DG TP+ +A +S D Sbjct: 156 LDNKHNTPLALAAELSNTNKTIETLIELGADVKIKNNDGITPLHLAAKSSSD 207 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 2/104 (1%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFAC-GYGELKCAEILLEAGAAVDALDKNKNTPLHYAA 322 ++ ++ GA+ ++ +G LH A + K E L+ GA V+A NTPLH AA Sbjct: 177 IETLIELGADVKIKNNDGITPLHLAAKSSSDSKTVETLILHGADVNATCSEGNTPLHDAA 236 Query: 321 -GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 Y +++L+++GA V N G TP+ A S++ V KL Sbjct: 237 TSYELSNTIEMLIEYGAEVNAANSVGDTPLHCA-ARSRNPVHKL 279 Score = 44.7 bits (104), Expect = 3e-04 Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 6/110 (5%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGE--LKCAEILLEAGAAVDALDKNKNTPLHYA 325 LK + G+N + + LH A Y + + ++L+E GA V+++D TP+HY Sbjct: 279 LKTLIAHGSNVNAVNGISVTPLHLAT-YSDNATEALKVLIEHGAEVNSVDIYGRTPMHYI 337 Query: 324 A----GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 + K V+LL++HGA + +N+ G TP+ A N+ + ++L+E Sbjct: 338 SRSYSSQSLKTAVELLVEHGADIEAKNVIGGTPLSSA-CNNIEYDLRLIE 386 Score = 40.0 bits (92), Expect = 0.007 Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 6/121 (4%) Frame = -3 Query: 534 VHNTASVGDA-EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEIL---LEAGAAV 367 +H + DA E ++ + GA+ + + ALH+A +L E+L + G V Sbjct: 28 LHKAVMLPDAVERIRMFVSKGADINVISDFKKTALHYAAK--KLATPEVLKTLIYLGTNV 85 Query: 366 DALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD--EVVKL 193 + D ++TPLHYA E LL GA + ++G+TP+ A + D E+V++ Sbjct: 86 NVTDMFESTPLHYAVQENGLEATKKLLDLGADPNTKYMNGQTPLHCAAMVIPDGPELVRI 145 Query: 192 L 190 L Sbjct: 146 L 146
>MTPN_HUMAN (P58546) Myotrophin (V-1 protein)| Length = 117 Score = 57.8 bits (138), Expect = 3e-08 Identities = 38/110 (34%), Positives = 56/110 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD + +K + G + + GR+ LH+A G+L+ E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 A G CV LLL GA ++ DG T E + ++ +K L Q Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEA----TDNQAIKALLQ 117
>MTPN_CANFA (Q863Z4) Myotrophin| Length = 117 Score = 57.8 bits (138), Expect = 3e-08 Identities = 38/110 (34%), Positives = 56/110 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 GD + +K + G + + GR+ LH+A G+L+ E LL GA ++A DK+ TPL Sbjct: 12 GDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPL 71 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 A G CV LLL GA ++ DG T E + ++ +K L Q Sbjct: 72 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEA----TDNQAIKALLQ 117
>ASB11_PONPY (Q5RFS1) Ankyrin repeat and SOCS box protein 11 (ASB-11)| Length = 323 Score = 57.8 bits (138), Expect = 3e-08 Identities = 39/117 (33%), Positives = 57/117 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H G E ++ L N D E + L+ AC Y + C + LLE GA+VD Sbjct: 165 SPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDH 224 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + +TPLH AA E + LL +GA + +N GK+ +++A S E LL Sbjct: 225 -GQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 280 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/117 (31%), Positives = 57/117 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A+ G LK + G N + + +LH AC G + CA+ LLE GA V+ Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + TPL A G CV++LL+ GA + + +PI A E +++L Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGAKAQFE-VHLASPIHEAVKRGHRECMEIL 182 Score = 48.1 bits (113), Expect = 2e-05 Identities = 41/114 (35%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 528 NTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKN 349 N G A + L+ GA K + +V +H A G +C EILL +D Sbjct: 137 NACCSGSAACVNVLLEFGA-KAQFEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQ 195 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAV-MLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A Y R +CV LL+ GA+V Q LD TP+ A S EV+ LL Sbjct: 196 LGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAAARQSNVEVIHLL 247
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/105 (35%), Positives = 48/105 (45%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E +K L G D +D G LH AC G + L EA +D +K TPLH A Sbjct: 560 EVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLA 619 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A G + V L GA+V DGKT ++A+ + V LL Sbjct: 620 ANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 664 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 2/119 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEI--LLEAGAAVDA 361 V+ A G + LK + D +D G ALH A YG A++ L G+ + Sbjct: 416 VYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVQVLCSFGSNPNI 475 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 DK + TPLH AA +G L + G V ++N +G+TP+ A ++V+ L + Sbjct: 476 QDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAE 534 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 1/103 (0%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G+N + +D E LH A +G A+ L EAG V+ ++ TPL A+ G + V Sbjct: 470 GSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 529 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQDVFL 172 + L +HGA + + DG + +A Q EV+K LL Q F+ Sbjct: 530 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFV 572 Score = 51.6 bits (122), Expect = 2e-06 Identities = 32/96 (33%), Positives = 49/96 (51%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + D +G ALH A +++ + LL G VD D++ NTPLH A G V Sbjct: 536 GADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIV 595 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L + + + N G+TP+ +A N +VV+ L Sbjct: 596 VALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 631 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/113 (27%), Positives = 54/113 (47%), Gaps = 2/113 (1%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A G+ + L+ + G+ D +D G A+++A +G + + L E +D DK+ Sbjct: 387 AGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGE 446 Query: 342 TPLHYAAGYGRKEC--VDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH AA YG + V +L G+ +Q+ + +TP+ A + V K L Sbjct: 447 MALHVAARYGHADVAQVQVLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKAL 499 Score = 46.6 bits (109), Expect = 7e-05 Identities = 38/117 (32%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G K + G N + ++ EG L A G E L E GA ++A D Sbjct: 484 LHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACD 543 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQDEVVKLLE 187 K+ + LH A + E + LL G V Q+ G TP+ VA K + VV L E Sbjct: 544 KDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 600
>PP16B_BOVIN (Q95N27) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (bTIMAP) (CAAX box protein TIMAP) Length = 568 Score = 57.4 bits (137), Expect = 4e-08 Identities = 34/97 (35%), Positives = 54/97 (55%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + D D +G LH A G L+ AE+LL+ G VD D + PLH AA +G+ + Sbjct: 219 GQDLDWVDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMA 278 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 +LL+ HGA++ + + PI++ + ++ V LLE Sbjct: 279 ELLVSHGASLSARTSMDEMPIDLCE--EEEFKVLLLE 313 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/96 (33%), Positives = 50/96 (52%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 DAE ++ L + D + +G ALH C + ++LL GA V+A D TPLH Sbjct: 80 DAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLH 139 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 AA G V +L+++GA ++ N DG P ++ + Sbjct: 140 AAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCE 175 Score = 39.7 bits (91), Expect = 0.009 Identities = 22/67 (32%), Positives = 34/67 (50%) Frame = -3 Query: 390 LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 ++ AG +D +D T LH A G +LLL HG V +++ DG P+ A Q Sbjct: 215 MIAAGQDLDWVDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQ 274 Query: 210 DEVVKLL 190 ++ +LL Sbjct: 275 MQMAELL 281 Score = 31.2 bits (69), Expect = 3.0 Identities = 26/98 (26%), Positives = 42/98 (42%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + + E AL A + + L+ + D +++ T LH +E V Sbjct: 58 GGRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIV 117 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LLL HGA V ++ + TP+ A +VK+L Q Sbjct: 118 KLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQ 155
>ACBD6_MOUSE (Q9D061) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 57.4 bits (137), Expect = 4e-08 Identities = 32/82 (39%), Positives = 46/82 (56%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D EGR LH+AC G + ++LL+ A ++ D T LHYAA + V+ Sbjct: 183 ADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVE 242 Query: 294 LLLKHGAAVMLQNLDGKTPIEV 229 LLL+ GA L++ DG P EV Sbjct: 243 LLLQSGADPTLRDQDGCLPEEV 264 Score = 38.5 bits (88), Expect = 0.019 Identities = 26/87 (29%), Positives = 43/87 (49%) Frame = -3 Query: 399 AEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKL 220 A+ + A V+ D+ LH+A G KE V +LL++ A + Q+ +G+T + A Sbjct: 175 AKAIKSKAADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAA 234 Query: 219 NSQDEVVKLLEQDVFL*SKPSDPVLID 139 ++V+LL Q +DP L D Sbjct: 235 CEFLDIVELLLQ------SGADPTLRD 255 Score = 33.1 bits (74), Expect = 0.80 Identities = 27/90 (30%), Positives = 42/90 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H G E +K L A + +D EG+ ALH+A L E+LL++GA Sbjct: 194 ALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVELLLQSGADPTL 253 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 D++ P G K LL +H A+ Sbjct: 254 RDQDGCLPEEVT---GCKAVSLLLQRHRAS 280
>FANK1_HUMAN (Q8TC84) Fibronectin type 3 and ankyrin repeat domains protein 1| Length = 345 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/98 (36%), Positives = 55/98 (56%), Gaps = 2/98 (2%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-TPL-HYAAGYGRKE 304 GA+ D+ G ALH+A G E +++ G VD +D TPL +A G + Sbjct: 200 GASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQR 259 Query: 303 CVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LL+ GA V +++ +GKTP+ VA LN+ +E+V+LL Sbjct: 260 VASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLL 297 Score = 53.9 bits (128), Expect = 4e-07 Identities = 30/77 (38%), Positives = 45/77 (58%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G + A +L++AGA V+ D+N TPL A +E V LLL GA ++N GK + Sbjct: 256 GNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVL 315 Query: 234 EVAKLNSQDEVVKLLEQ 184 E+A++ + VV LLE+ Sbjct: 316 EMARVFDRQSVVSLLEE 332
>ASB5_MOUSE (Q9D1A4) Ankyrin repeat and SOCS box protein 5 (ASB-5)| Length = 329 Score = 57.4 bits (137), Expect = 4e-08 Identities = 34/95 (35%), Positives = 48/95 (50%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H AS G L+ L G N + ++ LH AC + CA LLEAGA +A Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTIDHVTPLHEACLGDHVACARTLLEAGANANA 131 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 + + TPL A G C +LLL++GA L++ Sbjct: 132 ITIDGVTPLFNACSQGSASCAELLLEYGAKAQLES 166 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/116 (35%), Positives = 56/116 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S H AS G E L + G + D++ L+ AC + C LL AGA V Sbjct: 170 SPTHEAASKGHHECLDILIAWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLYAGADVHK 229 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 K +TPLH AA E V+LLL+ GA + +N D P+++A NS E + L Sbjct: 230 -GKYWDTPLHAAAQQPSTEIVNLLLEFGADINAKNTDLLRPVDLATSNSAVERILL 284 Score = 39.7 bits (91), Expect = 0.009 Identities = 26/81 (32%), Positives = 35/81 (43%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G ++ + R LH A G L LL G V+A+ + TPLH A C Sbjct: 60 GVSQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTIDHVTPLHEACLGDHVACA 119 Query: 297 DLLLKHGAAVMLQNLDGKTPI 235 LL+ GA +DG TP+ Sbjct: 120 RTLLEAGANANAITIDGVTPL 140
>AKR1_ASHGO (Q755Y0) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 724 Score = 57.4 bits (137), Expect = 4e-08 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D D G+ ALH+A G+ E LL+ A V +D TPLH+A G + L+ Sbjct: 186 DSPDPTGKTALHWAAYQGDPNTVEALLKFDADVRVVDTGGFTPLHWATVKGHPHVLKALI 245 Query: 285 KHGAAVMLQNLDGKTPIEVA-KLNSQ 211 +HG+ V L+N DGK + +A ++N+Q Sbjct: 246 EHGSDVFLKNNDGKNALMIAQEMNTQ 271 Score = 44.3 bits (103), Expect = 3e-04 Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDALDKNKNTPLHYAAGYGR 310 L+ GA+ D +G LH + E+ +L G VD+ D T LH+AA G Sbjct: 145 LEHGADPLITDRQGYNLLHTSTFSSEVMLITYVLFTGQIPVDSPDPTGKTALHWAAYQGD 204 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ---DVFL 172 V+ LLK A V + + G TP+ A + V+K L + DVFL Sbjct: 205 PNTVEALLKFDADVRVVDTGGFTPLHWATVKGHPHVLKALIEHGSDVFL 253 Score = 40.8 bits (94), Expect = 0.004 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 4/111 (3%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGA---NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 H GD + +K ++ G D ++ E LH+A L L+ GA V+ Sbjct: 60 HAACQRGDLKTVKDMIEAGVIDVKADWDEEEQVSGLHWASANNRLNLVRYLIAQGADVNI 119 Query: 360 LDKN-KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 + + TPLH+A+ G V LL+HGA ++ + G + + +S+ Sbjct: 120 KGGDLEATPLHWASKSGYVYIVHCLLEHGADPLITDRQGYNLLHTSTFSSE 170
>V218_FOWPV (Q9J517) Putative ankyrin repeat protein FPV218| Length = 461 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/117 (31%), Positives = 59/117 (50%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A D + + + GAN + +D +G LH A A+ILLE GA V+ Sbjct: 123 SFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSPLHHAVSKKTTLTAKILLENGARVNI 182 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D PLH G E V LL+ +G+ + +++++G TP+ A S + ++LL Sbjct: 183 RDSLGRLPLH--LGANTYEMVKLLIDYGSPIDIKDVNGSTPLHYAIWKSSLDTIRLL 237 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/92 (33%), Positives = 53/92 (57%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E +K +D G+ D +DV G LH+A L +L+ + ++ALD N N+PLHY Sbjct: 199 EMVKLLIDYGSPIDIKDVNGSTPLHYAIWKSSLDTIRLLVNV-STINALDNNCNSPLHYI 257 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEV 229 + V+LLL+ GA + ++++ G TP+++ Sbjct: 258 ILSETEILVELLLR-GADITIKDICGNTPLDI 288 Score = 46.6 bits (109), Expect = 7e-05 Identities = 39/144 (27%), Positives = 62/144 (43%) Frame = -3 Query: 621 NFPVDAATSTVLSGPQXXXXXXXXXXESIVHNTASVGDAEGLKKALDGGANKDEEDVEGR 442 N VD S +L G S +H+ S K L+ GA + D GR Sbjct: 131 NDDVDTVISLILHGANVNVQDSKGL--SPLHHAVSKKTTLTAKILLENGARVNIRDSLGR 188 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVML 262 LH E+ ++L++ G+ +D D N +TPLHYA + + LL+ L Sbjct: 189 LPLHLGANTYEM--VKLLIDYGSPIDIKDVNGSTPLHYAIWKSSLDTIRLLVNVSTINAL 246 Query: 261 QNLDGKTPIEVAKLNSQDEVVKLL 190 N + +P+ L+ + +V+LL Sbjct: 247 DN-NCNSPLHYIILSETEILVELL 269 Score = 40.0 bits (92), Expect = 0.007 Identities = 27/89 (30%), Positives = 45/89 (50%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D E R LH+A ++ L+ GA V+ D +PLH+A +LL++G Sbjct: 118 DRESRSFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSPLHHAVSKKTTLTAKILLENG 177 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A V +++ G+ P+ + + E+VKLL Sbjct: 178 ARVNIRDSLGRLPLHLGA--NTYEMVKLL 204 Score = 36.2 bits (82), Expect = 0.094 Identities = 22/76 (28%), Positives = 36/76 (47%) Frame = -3 Query: 417 YGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTP 238 Y ++L+ G V+ +D+ + LHYAA + V L+ HGA V +Q+ G +P Sbjct: 98 YVSFPIIKVLVYHGIDVNVIDRESRSFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSP 157 Query: 237 IEVAKLNSQDEVVKLL 190 + A K+L Sbjct: 158 LHHAVSKKTTLTAKIL 173
>OSBL1_MOUSE (Q91XL9) Oxysterol-binding protein-related protein 1 (OSBP-related| protein 1) (ORP-1) Length = 950 Score = 57.4 bits (137), Expect = 4e-08 Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 10/104 (9%) Frame = -3 Query: 513 GDAEGLKKALDGGANKD---EEDVEGRRA-------LHFACGYGELKCAEILLEAGAAVD 364 G+AE ++K L A + + D +GR LH AC +G + E LL+AGA V+ Sbjct: 16 GNAEEVRKLLAAMARMEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVEDLLKAGAKVN 75 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE 232 L+ +TPLH AA GRKE V LLL++ A + N G+T E Sbjct: 76 MLNDMGDTPLHRAAFTGRKELVLLLLEYDADSTVVNGSGQTAKE 119 Score = 45.1 bits (105), Expect = 2e-04 Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 4/78 (5%) Frame = -3 Query: 411 ELKCAEILLEAGAAVDALDKNKN----TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGK 244 +L A +E A +D ++K+ TPLH A +G K+ V+ LLK GA V + N G Sbjct: 23 KLLAAMARMEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVVEDLLKAGAKVNMLNDMGD 82 Query: 243 TPIEVAKLNSQDEVVKLL 190 TP+ A + E+V LL Sbjct: 83 TPLHRAAFTGRKELVLLL 100 Score = 39.3 bits (90), Expect = 0.011 Identities = 20/49 (40%), Positives = 31/49 (63%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 V+ D+ NTPLH AA K+CV LL+ GA L+N + + P+++A+ Sbjct: 169 VNCSDQLGNTPLHCAAYRAHKQCVLKLLRSGADPSLKNKNDQKPLDLAQ 217
>ASB9_MOUSE (Q91ZT8) Ankyrin repeat and SOCS box protein 9 (ASB-9)| Length = 290 Score = 57.4 bits (137), Expect = 4e-08 Identities = 36/109 (33%), Positives = 54/109 (49%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G + ++ GAN D L+ AC ++ CA+ LLE+G +V+ Sbjct: 132 SPIHEAAKRGYVKCIESLAAHGANIDYNISHLGTPLYVACKNQQVACAKKLLESGVSVNQ 191 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 K ++PLH A E V LL+ GA +N DGK P+++ L S Sbjct: 192 -GKGLDSPLHVVARMSSVELVHLLMDFGANAQAKNADGKRPVDLVPLES 239 Score = 52.0 bits (123), Expect = 2e-06 Identities = 26/54 (48%), Positives = 34/54 (62%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 LH AC G L CA +LL GA V+ + + TPL A G ++CV+LLL+HGA Sbjct: 69 LHEACLRGHLSCASVLLSHGAQVNGMTIDWRTPLFNACVSGSQDCVNLLLQHGA 122 Score = 45.1 bits (105), Expect = 2e-04 Identities = 28/84 (33%), Positives = 41/84 (48%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH A +G L L+ G V+ + + +PLH A G C +LL HGA V Sbjct: 36 LHDAAIHGCLLTLRNLISQGWPVNIITADHVSPLHEACLRGHLSCASVLLSHGAQVNGMT 95 Query: 255 LDGKTPIEVAKLNSQDEVVKLLEQ 184 +D +TP+ A ++ + V LL Q Sbjct: 96 IDWRTPLFNACVSGSQDCVNLLLQ 119
>V245_FOWPV (Q9J4Z5) Putative ankyrin repeat protein FPV245| Length = 436 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/117 (29%), Positives = 57/117 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 + +H D E +K + GA+ + +D G +H A + ++LLE GA + Sbjct: 126 TFLHYAIKNNDLEVIKMLFEYGADVNIKDDNGCYPIHIATRSNSYEIIKLLLEKGAYANV 185 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D N+PLH AA YG C+ L+L H + + +G TP+ A L ++ V L+ Sbjct: 186 KDNYGNSPLHNAAKYGDYACIKLVLDHTNNISNKCNNGVTPLHNAILYNRSAVELLI 242 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/105 (28%), Positives = 52/105 (49%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E +K LD G + ++ + + LH+A +L+ ++L E GA V+ D N P+H A Sbjct: 105 EMIKTILDSGVKVNTKNAKSKTFLHYAIKNNDLEVIKMLFEYGADVNIKDDNGCYPIHIA 164 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 E + LLL+ GA +++ G +P+ A +KL+ Sbjct: 165 TRSNSYEIIKLLLEKGAYANVKDNYGNSPLHNAAKYGDYACIKLV 209 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/119 (31%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +HN A GD +K LD N + G LH A Y + A LL +++ Sbjct: 192 SPLHNAAKYGDYACIKLVLDHTNNISNKCNNGVTPLHNAILYN--RSAVELLINNRSIND 249 Query: 360 LDKNKNTPLHYAAGYGRK-ECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQDEVVKLL 190 D + TPLHYA + +D+LL + A + +++ +G+ PI+ A K ++D V+K L Sbjct: 250 TDVDGYTPLHYALQPPCSIDIIDILLYNNADISIKDNNGRNPIDTAFKYINRDSVIKEL 308 Score = 33.1 bits (74), Expect = 0.80 Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Frame = -3 Query: 414 GELKCAEILLE-AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTP 238 G++ E L++ G ++ + TPL A G + V+L +KHGA V N P Sbjct: 12 GDISLVEKLIKNKGNCINISVEETTTPLIDAIRTGNAKIVELFIKHGAQVNHVNTKIPNP 71 Query: 237 IEVAKLNSQDEVVKLL 190 + A ++VKLL Sbjct: 72 LLTAIKIGSHDIVKLL 87
>Y045_METMA (Q8Q0U0) Hypothetical ANK-repeat protein MM0045| Length = 360 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/99 (32%), Positives = 58/99 (58%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 ++ GA+ + +D G AL +A G +L+E GA+++ D+ T L ++A GRK Sbjct: 253 VNAGADLNLQDKNGNTALIYAADRGYRDIVNLLIEGGASLNIPDEAGLTALMFSAQTGRK 312 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + V+LL+K GA + +++ + KT ++A +E+V LL Sbjct: 313 DIVELLIKAGADINIEDKNNKTAADLAAEVGFEEIVDLL 351 Score = 57.0 bits (136), Expect = 5e-08 Identities = 33/99 (33%), Positives = 57/99 (57%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 + GA+ + +D G+ AL A G E+L+ AGA ++ DKN NT L YAA G + Sbjct: 220 IKAGADLNIQDNSGKTALVAATKIGHKGIVELLVNAGADLNLQDKNGNTALIYAADRGYR 279 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + V+LL++ GA++ + + G T + + + ++V+LL Sbjct: 280 DIVNLLIEGGASLNIPDEAGLTALMFSAQTGRKDIVELL 318 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/96 (33%), Positives = 51/96 (53%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + +D G AL FA G A+ L++AG ++ D+N T L AA ++ Sbjct: 157 GADLNFQDENGETALKFAVKVGYKNIADQLIDAGTDLNIQDENGETALICAADRAHRDIA 216 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +LL+K GA + +Q+ GKT + A +V+LL Sbjct: 217 ELLIKAGADLNIQDNSGKTALVAATKIGHKGIVELL 252 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/97 (32%), Positives = 53/97 (54%), Gaps = 1/97 (1%) Frame = -3 Query: 513 GDAEGLKKALDGG-ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G E ++K L + + +D G+ AL A G +L+E+G +D D+N NT Sbjct: 78 GQTENVEKLLRSNKVDVNYQDAYGKTALISAADKGYRDVIGLLIESGPNLDLQDENGNTA 137 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 L AA R + +DLL+K+GA + Q+ +G+T ++ A Sbjct: 138 LISAAKIERGDIIDLLVKNGADLNFQDENGETALKFA 174 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/99 (32%), Positives = 50/99 (50%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 +D G + + +D G AL A AE+L++AGA ++ D + T L A G K Sbjct: 187 IDAGTDLNIQDENGETALICAADRAHRDIAELLIKAGADLNIQDNSGKTALVAATKIGHK 246 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V+LL+ GA + LQ+ +G T + A ++V LL Sbjct: 247 GIVELLVNAGADLNLQDKNGNTALIYAADRGYRDIVNLL 285 Score = 44.7 bits (104), Expect = 3e-04 Identities = 29/113 (25%), Positives = 54/113 (47%) Frame = -3 Query: 528 NTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKN 349 + A G + + ++ G N D +D G AL A ++L++ GA ++ D+N Sbjct: 107 SAADKGYRDVIGLLIESGPNLDLQDENGNTALISAAKIERGDIIDLLVKNGADLNFQDEN 166 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T L +A G K D L+ G + +Q+ +G+T + A + ++ +LL Sbjct: 167 GETALKFAVKVGYKNIADQLIDAGTDLNIQDENGETALICAADRAHRDIAELL 219
>PP16B_HUMAN (Q96T49) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4) Length = 567 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/97 (35%), Positives = 54/97 (55%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + D D +G LH A G L+ AE+LL+ G VD D + PLH AA +G+ + Sbjct: 219 GQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMA 278 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 +LL+ HGA++ + + PI++ + ++ V LLE Sbjct: 279 ELLVSHGASLSARTSMDEMPIDLCE--EEEFKVLLLE 313 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/96 (33%), Positives = 50/96 (52%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 DAE ++ L + D + +G ALH C + ++LL GA V+A D TPLH Sbjct: 80 DAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLH 139 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 AA G V +L+++GA ++ N DG P ++ + Sbjct: 140 AAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCE 175 Score = 40.0 bits (92), Expect = 0.007 Identities = 22/67 (32%), Positives = 34/67 (50%) Frame = -3 Query: 390 LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 ++ AG +D +D T LH A G +LLL HG V +++ DG P+ A Q Sbjct: 215 MIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQ 274 Query: 210 DEVVKLL 190 ++ +LL Sbjct: 275 MQMAELL 281 Score = 31.2 bits (69), Expect = 3.0 Identities = 26/98 (26%), Positives = 42/98 (42%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + + E AL A + + L+ + D +++ T LH +E V Sbjct: 58 GGRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIV 117 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LLL HGA V ++ + TP+ A +VK+L Q Sbjct: 118 KLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQ 155
>V244_FOWPV (Q9J4Z6) Putative ankyrin repeat protein FPV244| Length = 668 Score = 56.6 bits (135), Expect = 7e-08 Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 5/122 (4%) Frame = -3 Query: 540 SIVHNTASVGDA--EGLKKALDGGA---NKDEEDVEGRRALHFACGYGELKCAEILLEAG 376 SI+ N +G+A LK+ + G NK + +E + + EL AE+LL+ G Sbjct: 109 SIILNKHKLGEACIHVLKEGISGNEISYNKINKSIEYMKLIKERIQQDELLIAEMLLKKG 168 Query: 375 AAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 V+A D TP+HYAA G + V+LLL +GA V + LD + +E A + + +K Sbjct: 169 IDVNAKDVYCRTPIHYAAERGNTKMVNLLLSYGADVNIITLDDLSVLEYAVDSKNIDTIK 228 Query: 195 LL 190 + Sbjct: 229 AI 230 Score = 48.5 bits (114), Expect = 2e-05 Identities = 30/112 (26%), Positives = 58/112 (51%), Gaps = 1/112 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++ + + +K +D +N ++ D+ +A+ +L+ + +L ++G +V++ Sbjct: 213 SVLEYAVDSKNIDTIKAIIDNRSNINKNDLSLLKAIRNT----DLETSLLLYDSGFSVNS 268 Query: 360 LDKNKNTPLHYAA-GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD 208 +D KNTPLHYA V LL+ G V +N+ G+TP+ + N D Sbjct: 269 IDVYKNTPLHYAVQAPSLSRLVPKLLERGIDVNAKNIKGETPLYLMAKNGYD 320 Score = 45.4 bits (106), Expect = 2e-04 Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAA-GYGR 310 L+ GAN + D + +H+A + LL+ GA ++AL + T LH+A G Sbjct: 362 LELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTVLHFALYGTNP 421 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQDEVVKLL 190 V L+ GA V +N TP+ A K N + EV+K+L Sbjct: 422 YMSVKTLIDRGANVNSKNKYLSTPLHYACKKNCKPEVIKML 462 Score = 38.1 bits (87), Expect = 0.025 Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 1/82 (1%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEI-LLEAGAAVDALDKNKNTPL 334 D E ++ + GA+ + D LH A K I LLE GA V+A D TP+ Sbjct: 320 DTENIRTLIMRGADVNAADSLYITPLHQASTLDRYKDTVITLLELGANVNARDYCDKTPI 379 Query: 333 HYAAGYGRKECVDLLLKHGAAV 268 HYAA ++ LL +GA + Sbjct: 380 HYAAVRNNVVIINTLLDYGADI 401 Score = 33.1 bits (74), Expect = 0.80 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYG-ELKCAEILLEAGAAVDALDKNKNTPLHYAA 322 +K +D GAN + ++ LH+AC + + ++LL+ GA V+A++ PL A Sbjct: 425 VKTLIDRGANVNSKNKYLSTPLHYACKKNCKPEVIKMLLDNGADVNAINIRNQYPLLIAL 484 Query: 321 GYGRKECVDLLLKHGA 274 Y V++LL +GA Sbjct: 485 EY--HGIVNILLHYGA 498
>ACBD6_BRARE (Q4V8X4) Acyl-CoA-binding domain-containing protein 6| Length = 300 Score = 56.6 bits (135), Expect = 7e-08 Identities = 30/87 (34%), Positives = 48/87 (55%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D EGR LH+AC G +LL+ A +++ D T LHYA+ E V+LLLK G Sbjct: 207 DEEGRALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELLLKAG 266 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVK 196 A +++ +G P EV + ++ +++ Sbjct: 267 ADPSIKDQEGSLPEEVTESSAISSLLR 293 Score = 36.6 bits (83), Expect = 0.072 Identities = 20/60 (33%), Positives = 33/60 (55%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V+ D+ LH+A G K+ V LLL++ A + Q+ +G+T + A E+V+LL Sbjct: 203 VNTRDEEGRALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELL 262 Score = 34.3 bits (77), Expect = 0.36 Identities = 19/68 (27%), Positives = 34/68 (50%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H G + + L A+ + +D EG+ ALH+A + E+LL+AGA Sbjct: 212 ALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELLLKAGADPSI 271 Query: 360 LDKNKNTP 337 D+ + P Sbjct: 272 KDQEGSLP 279
>CT086_HUMAN (Q9BZ19) Hypothetical protein C20orf86| Length = 240 Score = 56.6 bits (135), Expect = 7e-08 Identities = 29/71 (40%), Positives = 42/71 (59%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 AL+ A G + LLE GA+ + TPLH AA GR +C+ LLL+HGA++ + Sbjct: 118 ALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDR 177 Query: 258 NLDGKTPIEVA 226 + G+TPI +A Sbjct: 178 DAKGETPISIA 188 Score = 33.1 bits (74), Expect = 0.80 Identities = 17/51 (33%), Positives = 30/51 (58%) Frame = -3 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 L+ A+ G + V LL+HGA+ + ++ G+TP+ VA + + + LL Q Sbjct: 119 LYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQ 169
>ASZ1_CALJA (Q2QLG0) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 477 Score = 56.6 bits (135), Expect = 7e-08 Identities = 48/148 (32%), Positives = 62/148 (41%), Gaps = 37/148 (25%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE----LKCAEILLE--------- 382 ASV +AE ++ LD GAN E + + +G LKC E+LL Sbjct: 89 ASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVAC 148 Query: 381 ------------------------AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 +GA V+ D+N T L +AA G K V LL+ GA Sbjct: 149 RRLMTPIMYAARDGHTQVVALLVASGAEVNTQDENGYTALTWAARQGHKSIVLKLLELGA 208 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 MLQ DGK P E+AK N E+ LL Sbjct: 209 NKMLQTKDGKLPSEIAKRNKHHEIFNLL 236 Score = 31.6 bits (70), Expect = 2.3 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 3/91 (3%) Frame = -3 Query: 414 GELKCAEILLEAGA-AVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTP 238 G++ LL++G +VDA + TPL YAA E V +LL GA + D +T Sbjct: 58 GDVSLVLELLDSGIISVDATFRYGWTPLMYAASVANAELVRVLLDRGANASFEK-DKQTI 116 Query: 237 IEVA--KLNSQDEVVKLLEQDVFL*SKPSDP 151 + A S+++++K +E L S+ +DP Sbjct: 117 LITACSAHGSEEQILKCVE---LLLSRNADP 144
>ASB12_MOUSE (Q9D738) Ankyrin repeat and SOCS box protein 12 (ASB-12)| Length = 308 Score = 56.6 bits (135), Expect = 7e-08 Identities = 32/84 (38%), Positives = 45/84 (53%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 L A YG L C ++LLE GA VD+LD TPL A +G ECV +LL+ GA Sbjct: 68 LRLAASYGHLNCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRMLLEAGACPSGSI 127 Query: 255 LDGKTPIEVAKLNSQDEVVKLLEQ 184 + +P+ A S+D +L++ Sbjct: 128 YNNCSPVLTA---SRDGAFAILQE 148 Score = 50.1 bits (118), Expect = 6e-06 Identities = 34/103 (33%), Positives = 50/103 (48%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 AS G +K L+ GA+ D DV+ + L A +G L+C +LLEAGA N Sbjct: 72 ASYGHLNCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRMLLEAGACPSGSIYNNC 131 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 +P+ A+ G + LL HGA N+ K P+ + + S Sbjct: 132 SPVLTASRDGAFAILQELLGHGAEA---NVKAKLPVWASNIAS 171 Score = 41.2 bits (95), Expect = 0.003 Identities = 21/51 (41%), Positives = 30/51 (58%) Frame = -3 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL AA YG CV +LL+HGA V ++ +TP+ A + E V++L Sbjct: 66 TPLRLAASYGHLNCVKVLLEHGADVDSLDVKAQTPLFTAVSHGHLECVRML 116
>ASZ1_CALMO (Q2QLB5) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 476 Score = 56.2 bits (134), Expect = 9e-08 Identities = 48/148 (32%), Positives = 61/148 (41%), Gaps = 37/148 (25%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE----LKCAEILLE--------- 382 ASV +AE ++ LD GAN E + + +G LKC E+LL Sbjct: 88 ASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVAC 147 Query: 381 ------------------------AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 GA V+ D+N T L +AA G K V LL+ GA Sbjct: 148 RRLMTPIMYAARDGHTQVVALLVAGGAEVNTQDENGYTALTWAARQGHKSIVLKLLELGA 207 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 MLQ DGK P E+AK N E+ LL Sbjct: 208 NKMLQTKDGKLPSEIAKRNKHHEIFNLL 235 Score = 38.1 bits (87), Expect = 0.025 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++ + LL++G +VDA + TPL YAA E V +LL GA + D +T + Sbjct: 58 GDVSLVQELLDSGISVDATFRYGWTPLMYAASVANAELVRVLLDRGANASFEK-DKQTIL 116 Query: 234 EVA--KLNSQDEVVKLLEQDVFL*SKPSDP 151 A S+++++K +E L S+ +DP Sbjct: 117 ITACSAHGSEEQILKCVE---LLLSRNADP 143 Score = 38.1 bits (87), Expect = 0.025 Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 5/115 (4%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 + GD +++ LD G + D G L +A + +LL+ GA + +K+K T Sbjct: 56 TTGDVSLVQELLDSGISVDATFRYGWTPLMYAASVANAELVRVLLDRGANA-SFEKDKQT 114 Query: 339 PLHYA-AGYGRKE----CVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L A + +G +E CV+LLL A + TPI A + +VV LL Sbjct: 115 ILITACSAHGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALL 169
>IKBE_HUMAN (O00221) NF-kappa-B inhibitor epsilon (NF-kappa-BIE)| (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE) Length = 361 Score = 56.2 bits (134), Expect = 9e-08 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 1/89 (1%) Frame = -3 Query: 486 LDGGANKD-EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 L GA+ D +E G+ ALH A E + LL+AGA VDA N TPLH AAG G Sbjct: 251 LRNGADIDVQEGSSGKTALHLAVETQERGLVQFLLQAGAQVDARMLNGCTPLHLAAGRGL 310 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 L K GA +L+N++ +TP ++ + Sbjct: 311 MGISSTLCKAGADSLLRNVEDETPQDLTE 339
>ASB9_HUMAN (Q96DX5) Ankyrin repeat and SOCS box protein 9 (ASB-9)| Length = 294 Score = 56.2 bits (134), Expect = 9e-08 Identities = 40/117 (34%), Positives = 58/117 (49%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G L+ + G + + LH AC G L C +ILL+ GA V+ Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + +TPL A G +CV+LLL+HGA+V ++ D +PI A E V L Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPES-DLASPIHEAARRGHVECVNSL 153 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/104 (31%), Positives = 51/104 (49%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G E + + G N D + L+ AC + C + LLE+GA V+ Sbjct: 136 SPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQ 195 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEV 229 K +++PLH A +E LL+ GA +N +GK P+E+ Sbjct: 196 -GKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 238 Score = 43.9 bits (102), Expect = 5e-04 Identities = 29/84 (34%), Positives = 41/84 (48%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 +H A +G L+ G AV+ + + +PLH A G CV +LLKHGA V Sbjct: 40 MHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNGVT 99 Query: 255 LDGKTPIEVAKLNSQDEVVKLLEQ 184 D TP+ A ++ + V LL Q Sbjct: 100 ADWHTPLFNACVSGSWDCVNLLLQ 123 Score = 37.0 bits (84), Expect = 0.055 Identities = 26/97 (26%), Positives = 44/97 (45%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + + E D+ +H A G ++C L+ G +D + TPL+ A ++ C Sbjct: 125 GASVQPESDLAS--PIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRAC 182 Query: 300 VDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V LL+ GA V Q +P+ + +E+ LL Sbjct: 183 VKKLLESGADVN-QGKGQDSPLHAVARTASEELACLL 218
>USH1G_MOUSE (Q80T11) Usher syndrome type-1G protein homolog (Scaffold protein| containing ankyrin repeats and SAM domain) (Jackson shaker protein) Length = 461 Score = 56.2 bits (134), Expect = 9e-08 Identities = 36/115 (31%), Positives = 54/115 (46%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 H A G E LK+A N +ED G +A +G L+ +++ G D D Sbjct: 6 HRAARDGYLELLKEATRKELNAPDED--GMTPTLWAAYHGNLESLRLIVSRGGDPDKCDI 63 Query: 351 NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 NTPLH AA G C+ L+ GA + + D TP+++A + E V+ L+ Sbjct: 64 WGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLD 118
>USH1G_HUMAN (Q495M9) Usher syndrome type-1G protein (Scaffold protein| containing ankyrin repeats and SAM domain) Length = 461 Score = 56.2 bits (134), Expect = 9e-08 Identities = 36/115 (31%), Positives = 54/115 (46%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 H A G E LK+A N +ED G +A +G L+ +++ G D D Sbjct: 6 HRAARDGYLELLKEATRKELNAPDED--GMTPTLWAAYHGNLESLRLIVSRGGDPDKCDI 63 Query: 351 NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 NTPLH AA G C+ L+ GA + + D TP+++A + E V+ L+ Sbjct: 64 WGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLD 118
>GORK_ARATH (Q94A76) Potassium channel GORK (Guard cell outward rectifying K(+)| channel) (AtGORK) Length = 820 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/79 (39%), Positives = 46/79 (58%) Frame = -3 Query: 525 TASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNK 346 T + GD++ LK+ L G N + ED + R LH A G A++L+EAGA+V + D+ Sbjct: 635 TVAKGDSDFLKRLLSSGMNPNSEDYDHRTPLHVAASEGLFLMAKMLVEAGASVISKDRWG 694 Query: 345 NTPLHYAAGYGRKECVDLL 289 N+PL A G K+ + LL Sbjct: 695 NSPLDEARLCGNKKLIKLL 713 Score = 52.8 bits (125), Expect = 1e-06 Identities = 35/107 (32%), Positives = 54/107 (50%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 V++ A GD LK + GA+ ++ D +GR LH A G L++ G V+ D Sbjct: 535 VNSAAFQGDFYQLKSLIRSGADPNKTDYDGRSPLHLAACRGYEDITLFLIQEGVDVNLKD 594 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 K +TPL A G++ + LL+K GA+ L++ VAK +S Sbjct: 595 KFGHTPLFEAVKAGQEGVIGLLVKEGASFNLEDSGNFLCTTVAKGDS 641 Score = 38.1 bits (87), Expect = 0.025 Identities = 25/94 (26%), Positives = 48/94 (51%) Frame = -3 Query: 462 EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLK 283 +++ E ++ A G+ + L+ +GA + D + +PLH AA G ++ L++ Sbjct: 526 KQEAELALKVNSAAFQGDFYQLKSLIRSGADPNKTDYDGRSPLHLAACRGYEDITLFLIQ 585 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 G V L++ G TP+ A Q+ V+ LL ++ Sbjct: 586 EGVDVNLKDKFGHTPLFEAVKAGQEGVIGLLVKE 619
>ASZ1_PAPAN (Q8WMX7) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.8 bits (133), Expect = 1e-07 Identities = 48/148 (32%), Positives = 61/148 (41%), Gaps = 37/148 (25%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE----LKCAEILLEA-------- 379 ASV +AE ++ LD GAN E + + +G LKC E+LL Sbjct: 87 ASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVAC 146 Query: 378 -------------------------GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 GA V+ D+N T L +AA G K V LL+ GA Sbjct: 147 RRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGA 206 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 MLQ DGK P E+AK N E+ LL Sbjct: 207 NKMLQTKDGKMPSEIAKRNKHHEIFNLL 234 Score = 40.0 bits (92), Expect = 0.007 Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 ++GD +++ LD G + D G L +A + +LL+ GA + +K+K T Sbjct: 55 TIGDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANA-SFEKDKQT 113 Query: 339 PLHYA-AGYGRKE----CVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L A + +G +E CV+LLL A + TPI A + +VV LL Sbjct: 114 ILITACSAHGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALL 168 Score = 36.6 bits (83), Expect = 0.072 Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 2/90 (2%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++ + LL++G +VD+ + TPL YAA E V +LL GA + D +T + Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEK-DKQTIL 115 Query: 234 EVA--KLNSQDEVVKLLEQDVFL*SKPSDP 151 A S+++++K +E L S+ +DP Sbjct: 116 ITACSAHGSEEQILKCVE---LLLSRNADP 142
>ASZ1_PANTR (Q8WMX6) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.8 bits (133), Expect = 1e-07 Identities = 48/148 (32%), Positives = 61/148 (41%), Gaps = 37/148 (25%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE----LKCAEILLEA-------- 379 ASV +AE ++ LD GAN E + + +G LKC E+LL Sbjct: 87 ASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSEEQILKCVELLLSRNADPNVAC 146 Query: 378 -------------------------GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 GA V+ D+N T L +AA G K V LL+ GA Sbjct: 147 RRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGA 206 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 MLQ DGK P E+AK N E+ LL Sbjct: 207 NKMLQTKDGKMPSEIAKRNKHHEIFNLL 234 Score = 36.2 bits (82), Expect = 0.094 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++ + LL++G +VD+ + TPL YAA E V +LL GA + I Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILI 116 Query: 234 EVAKLN-SQDEVVKLLEQDVFL*SKPSDP 151 + S+++++K +E L S+ +DP Sbjct: 117 TACSAHGSEEQILKCVE---LLLSRNADP 142
>ASZ1_HUMAN (Q8WWH4) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.8 bits (133), Expect = 1e-07 Identities = 48/148 (32%), Positives = 61/148 (41%), Gaps = 37/148 (25%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE----LKCAEILLEA-------- 379 ASV +AE ++ LD GAN E + + +G LKC E+LL Sbjct: 87 ASVANAELVRVLLDRGANASFEKDKQSILITACSAHGSEEQILKCVELLLSRNADPNVAC 146 Query: 378 -------------------------GAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 GA V+ D+N T L +AA G K V LL+ GA Sbjct: 147 RRLMTPIMYAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGA 206 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 MLQ DGK P E+AK N E+ LL Sbjct: 207 NKMLQTKDGKMPSEIAKRNKHHEIFNLL 234 Score = 35.4 bits (80), Expect = 0.16 Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 1/89 (1%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++ + LL++G +VD+ + TPL YAA E V +LL GA + I Sbjct: 57 GDVSLVQELLDSGISVDSNFQYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQSILI 116 Query: 234 EVAKLN-SQDEVVKLLEQDVFL*SKPSDP 151 + S+++++K +E L S+ +DP Sbjct: 117 TACSAHGSEEQILKCVE---LLLSRNADP 142
>ANR10_HUMAN (Q9NXR5) Ankyrin repeat domain-containing protein 10| Length = 420 Score = 55.8 bits (133), Expect = 1e-07 Identities = 46/160 (28%), Positives = 69/160 (43%), Gaps = 11/160 (6%) Frame = -3 Query: 636 EAMSLNFPV-----DAATSTVLSGPQXXXXXXXXXXESI-----VHNTASVGDAEGLKKA 487 E +SL FP+ D +T+ S Q +S VH A G E L + Sbjct: 18 ELLSLRFPLHRACRDGDLATLCSLLQQTPHAHLASEDSFYGWTPVHWAAHFGKLECLVQL 77 Query: 486 LDGGANKDEEDVE-GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 + GA + + H A G +C L++AGA ++ D TP+H AA G Sbjct: 78 VRAGATLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGS 137 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 EC+ L+ +GA V L+N G T ++A+ E + L Sbjct: 138 LECISALVANGAHVDLRNASGLTAADIAQTQGFQECAQSL 177 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/82 (32%), Positives = 37/82 (45%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 H A G + L + GAN ++ D EG +H A G L+C L+ GA VD + Sbjct: 97 HIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVANGAHVDLRNA 156 Query: 351 NKNTPLHYAAGYGRKECVDLLL 286 + T A G +EC LL Sbjct: 157 SGLTAADIAQTQGFQECAQSLL 178
>ASZ1_PONPY (Q2IBE3) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/80 (41%), Positives = 43/80 (53%) Frame = -3 Query: 429 FACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD 250 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA MLQ D Sbjct: 155 YAARDGHTQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNIVLKLLELGANKMLQTKD 214 Query: 249 GKTPIEVAKLNSQDEVVKLL 190 GK P E+AK N E+ LL Sbjct: 215 GKMPSEIAKRNKHHEIFNLL 234 Score = 35.8 bits (81), Expect = 0.12 Identities = 25/88 (28%), Positives = 44/88 (50%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++ + LL++G +VD+ + TPL YAA E V +LL GA + K I Sbjct: 57 GDVSLVQELLDSGISVDSTFQYGWTPLMYAASVANAELVRVLLDRGANASFEK--DKQSI 114 Query: 234 EVAKLNSQDEVVKLLEQDVFL*SKPSDP 151 + +++ ++L+ L S+ +DP Sbjct: 115 LITACSARGSEEQILKCVELLLSRNADP 142
>Y196_THEAC (Q9HLN1) Hypothetical ANK-repeat protein Ta0196| Length = 208 Score = 55.5 bits (132), Expect = 1e-07 Identities = 29/92 (31%), Positives = 50/92 (54%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D+ D+EG AL +A ++ A+ L+ ++D D NTP+ +A +G + V LL+ Sbjct: 77 DDRDIEGNTALMWAVRNNRMESAKSLIALKCSIDIPDSAGNTPICWAVIFGYTDMVKLLI 136 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 GA + + N +G TP +A + E +K+L Sbjct: 137 SSGANINISNDEGDTPAILASKYGRSECLKML 168 Score = 42.7 bits (99), Expect = 0.001 Identities = 22/92 (23%), Positives = 49/92 (53%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D D G + +A +G ++L+ +GA ++ + +TP A+ YGR EC+ +L+ Sbjct: 110 DIPDSAGNTPICWAVIFGYTDMVKLLISSGANINISNDEGDTPAILASKYGRSECLKMLI 169 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + G + +N + + + A+ + E++++L Sbjct: 170 EAGCDLNAKNHNAQNVWKAAEAFGRKEILEVL 201 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/75 (30%), Positives = 39/75 (52%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + +K + GAN + + EG A YG +C ++L+EAG ++A + N Sbjct: 127 GYTDMVKLLISSGANINISNDEGDTPAILASKYGRSECLKMLIEAGCDLNAKNHNAQNVW 186 Query: 333 HYAAGYGRKECVDLL 289 A +GRKE +++L Sbjct: 187 KAAEAFGRKEILEVL 201
>ASB11_MOUSE (Q9CQ31) Ankyrin repeat and SOCS box protein 11 (ASB-11)| Length = 323 Score = 55.5 bits (132), Expect = 1e-07 Identities = 40/121 (33%), Positives = 58/121 (47%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A+ G LK + G N + + +LH AC G + CA+ LLE GA V+A Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGINVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNA 126 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 + TPL A G CV++LL+ GA L+ E K ++ + LL +D Sbjct: 127 QTVHGATPLFNACCSGSAACVNVLLEFGAKAQLEIYLASPIHEAVKRGHRECMEILLTKD 186 Query: 180 V 178 V Sbjct: 187 V 187 Score = 55.1 bits (131), Expect = 2e-07 Identities = 37/119 (31%), Positives = 59/119 (49%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H G E ++ L N ++E + L+ AC Y + C + LLE GA+VD Sbjct: 165 SPIHEAVKRGHRECMEILLTKDVNIEQEVPQLGTPLYVACTYQRVDCVKKLLELGASVDH 224 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + +TPLH A E ++LL +GA + L+N GK+ +++A S LL + Sbjct: 225 -GQWLDTPLHAAVRQSSVEVINLLTVYGANLNLRNAQGKSALDLAVPKSSVRQALLLHE 282 Score = 45.8 bits (107), Expect = 1e-04 Identities = 39/114 (34%), Positives = 54/114 (47%), Gaps = 1/114 (0%) Frame = -3 Query: 528 NTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKN 349 N G A + L+ GA K + ++ +H A G +C EILL ++ Sbjct: 137 NACCSGSAACVNVLLEFGA-KAQLEIYLASPIHEAVKRGHRECMEILLTKDVNIEQEVPQ 195 Query: 348 KNTPLHYAAGYGRKECVDLLLKHGAAV-MLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL+ A Y R +CV LL+ GA+V Q LD TP+ A S EV+ LL Sbjct: 196 LGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAAVRQSSVEVINLL 247
>ASZ1_MOUSE (Q8VD46) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/80 (40%), Positives = 44/80 (55%) Frame = -3 Query: 429 FACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD 250 +A G + +L+ GA V+A D+N T L +AA G K + LL+ GA MLQ D Sbjct: 155 YAARDGHTQVVALLVAHGAEVNAQDENGYTALTWAARQGHKNVILKLLELGANKMLQTKD 214 Query: 249 GKTPIEVAKLNSQDEVVKLL 190 G+TP E+AK N E+ L Sbjct: 215 GRTPSEIAKRNKHLEIFNFL 234 Score = 43.5 bits (101), Expect = 6e-04 Identities = 39/149 (26%), Positives = 57/149 (38%), Gaps = 38/149 (25%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGE----------------------- 409 + GD +K+ LD G N D G L +A Sbjct: 55 TTGDISLVKELLDSGINVDSSFRYGWTPLMYAASVANAELVRFLLDRGANASFDKDKLTI 114 Query: 408 --------------LKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 LKC E+LL A + + TP+ YAA G + V LL+ HGA Sbjct: 115 LISACSARGSEEQVLKCVELLLSRNADPNTACRRLMTPIMYAARDGHTQVVALLVAHGAE 174 Query: 270 VMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 V Q+ +G T + A+ ++ ++KLLE Sbjct: 175 VNAQDENGYTALTWAARQGHKNVILKLLE 203 Score = 33.9 bits (76), Expect = 0.47 Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 3/91 (3%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++ + LL++G VD+ + TPL YAA E V LL GA K I Sbjct: 57 GDISLVKELLDSGINVDSSFRYGWTPLMYAASVANAELVRFLLDRGANASFDK--DKLTI 114 Query: 234 EVAKLN---SQDEVVKLLEQDVFL*SKPSDP 151 ++ + S+++V+K +E L S+ +DP Sbjct: 115 LISACSARGSEEQVLKCVE---LLLSRNADP 142
>ASB4_HUMAN (Q9Y574) Ankyrin repeat and SOCS box protein 4 (ASB-4)| Length = 426 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + + + +K D GA + + G ALHF + CA+ L+ GA V+ Sbjct: 111 LHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKT 170 Query: 354 KNKN--TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 N++ TPLH AA +G E V ++HGA V N +TP+ +A Sbjct: 171 NNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIA 215 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 2/114 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G E L LD A + G+ LH AC + C +IL + GA ++ Sbjct: 79 LHLSVLFGHVECLLVLLDHNATINCRP-NGKTPLHVACEMANVDCVKILCDRGAKLNCYS 137 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ--NLDGKTPIEVAKLNSQDEVV 199 + +T LH+ C L+ GA V ++ N D +TP+ A E+V Sbjct: 138 LSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLSELV 191 Score = 33.9 bits (76), Expect = 0.47 Identities = 19/51 (37%), Positives = 30/51 (58%) Frame = -3 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LH + +G EC+ +LL H A + + +GKTP+ VA + + VK+L Sbjct: 77 TGLHLSVLFGHVECLLVLLDHNATINCRP-NGKTPLHVACEMANVDCVKIL 126
>MIB2_MOUSE (Q8R516) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike) Length = 973 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/99 (33%), Positives = 48/99 (48%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A +G E ++ L A+ D D EG LH+ + + +LL AG AVDA + ++ Sbjct: 489 AYLGQVELVRLLLQARASMDLPDDEGNTVLHYTAMGNQPEATRVLLSAGCAVDARNGTRS 548 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 T LH A G E V +L + G V L + TP+ A Sbjct: 549 TALHVAVQRGFLEVVKILCERGCDVNLPDAHADTPLHSA 587 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/87 (37%), Positives = 46/87 (52%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +GR AL A G+++ +LL+A A++D D NT LHY A + E +LL G A Sbjct: 480 QGRTALQVAAYLGQVELVRLLLQARASMDLPDDEGNTVLHYTAMGNQPEATRVLLSAGCA 539 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V +N T + VA EVVK+L Sbjct: 540 VDARNGTRSTALHVAVQRGFLEVVKIL 566 Score = 46.2 bits (108), Expect = 9e-05 Identities = 36/110 (32%), Positives = 50/110 (45%), Gaps = 3/110 (2%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H TA E + L G D + ALH A G L+ +IL E G V+ Sbjct: 516 TVLHYTAMGNQPEATRVLLSAGCAVDARNGTRSTALHVAVQRGFLEVVKILCERGCDVNL 575 Query: 360 LDKNKNTPLHYA--AGYGRKECVDLLLK-HGAAVMLQNLDGKTPIEVAKL 220 D + +TPLH A AG G V++L + G V N G T + A L Sbjct: 576 PDAHADTPLHSAISAGAGASSIVEVLTEVPGIDVTATNSQGFTLLHHASL 625
>PP16B_MOUSE (Q8VHQ3) Protein phosphatase 1 regulatory inhibitor subunit 16B| (TGF-beta-inhibited membrane-associated protein) (CAAX box protein TIMAP) Length = 568 Score = 54.7 bits (130), Expect = 3e-07 Identities = 34/97 (35%), Positives = 53/97 (54%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + D D +G LH A G L+ AE+LL+ G VD D + PLH AA +G+ Sbjct: 219 GQDLDWIDGQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMPMA 278 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 +LL+ HGA++ + + PI++ + ++ V LLE Sbjct: 279 ELLVSHGASLSARTSMDEMPIDLCE--EEEFKVLLLE 313 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/96 (33%), Positives = 50/96 (52%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 DAE ++ L + D + +G ALH C + ++LL GA V+A D TPLH Sbjct: 80 DAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLH 139 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 AA G V +L+++GA ++ N DG P ++ + Sbjct: 140 AAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCE 175 Score = 38.5 bits (88), Expect = 0.019 Identities = 22/67 (32%), Positives = 33/67 (49%) Frame = -3 Query: 390 LLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 ++ AG +D +D T LH A G +LLL HG V +++ DG P+ A Q Sbjct: 215 MIAAGQDLDWIDGQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQ 274 Query: 210 DEVVKLL 190 + +LL Sbjct: 275 MPMAELL 281 Score = 31.2 bits (69), Expect = 3.0 Identities = 26/98 (26%), Positives = 42/98 (42%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G + + E AL A + + L+ + D +++ T LH +E V Sbjct: 58 GGRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIV 117 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LLL HGA V ++ + TP+ A +VK+L Q Sbjct: 118 KLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQ 155
>ACBD6_HUMAN (Q9BR61) Acyl-CoA-binding domain-containing protein 6| Length = 282 Score = 54.7 bits (130), Expect = 3e-07 Identities = 30/77 (38%), Positives = 43/77 (55%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKH 280 +D EGR LH+AC G + +LL+ A ++ D T LHYA+ + V+LLL+ Sbjct: 188 KDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQS 247 Query: 279 GAAVMLQNLDGKTPIEV 229 GA L++ DG P EV Sbjct: 248 GADPTLRDQDGCLPEEV 264 Score = 38.5 bits (88), Expect = 0.019 Identities = 25/77 (32%), Positives = 39/77 (50%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V+ D+ LH+A G KE V +LL+H A + Q+ +G+T + A ++V+LL Sbjct: 185 VNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELL 244 Query: 189 EQDVFL*SKPSDPVLID 139 Q +DP L D Sbjct: 245 LQ------SGADPTLRD 255 Score = 30.8 bits (68), Expect = 4.0 Identities = 20/68 (29%), Positives = 34/68 (50%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H G E + L A+ + +D EG+ ALH+A L E+LL++GA Sbjct: 194 ALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTL 253 Query: 360 LDKNKNTP 337 D++ P Sbjct: 254 RDQDGCLP 261
>AKR1_CRYNE (Q5KP49) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 776 Score = 54.7 bits (130), Expect = 3e-07 Identities = 29/81 (35%), Positives = 49/81 (60%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 DE+D +G AL +A G+ ++L+ GA+V++ D TPLH+AA G K + L+ Sbjct: 198 DEKDTDGHTALMWAAYQGDALSVDLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLV 257 Query: 285 KHGAAVMLQNLDGKTPIEVAK 223 + GA++ + GKTP ++A+ Sbjct: 258 EAGASLDAKEEAGKTPRDMAE 278 Score = 43.5 bits (101), Expect = 6e-04 Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + D +G LH + +L A+D D + +T L +AA G V Sbjct: 161 GADPNIHDSQGFNTLHLITHSSAVMPLLYMLHQPVAIDEKDTDGHTALMWAAYQGDALSV 220 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKL-NSQDEVVKLLEQDVFL*SK 163 DLL++HGA+V + G TP+ A + ++ ++ L+E L +K Sbjct: 221 DLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLVEAGASLDAK 266 Score = 41.2 bits (95), Expect = 0.003 Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Frame = -3 Query: 534 VHNTASVGDAEGLKKAL--DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +H A GD + L + N D + LH+A + +L+++GA +DA Sbjct: 73 IHALAQRGDTAAIAAMLQENPSLNLSARDAQDVTPLHWAAINAHMGTCRLLIDSGADIDA 132 Query: 360 L-DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 + + K TPL +AA G V LL+ GA + + G + + ++ ++ +L Sbjct: 133 IGGELKATPLQWAARNGHLYVVHLLISRGADPNIHDSQGFNTLHLITHSSAVMPLLYMLH 192 Query: 186 QDVFL*SKPSD 154 Q V + K +D Sbjct: 193 QPVAIDEKDTD 203 Score = 33.1 bits (74), Expect = 0.80 Identities = 20/59 (33%), Positives = 30/59 (50%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 GDA + + GA+ + D G LH+A G L+EAGA++DA ++ TP Sbjct: 215 GDALSVDLLIRHGASVNSTDNAGMTPLHWAAVKGNKVSIMHLVEAGASLDAKEEAGKTP 273
>ASB4_MOUSE (Q9WV71) Ankyrin repeat and SOCS box protein 4 (ASB-4)| Length = 426 Score = 54.7 bits (130), Expect = 3e-07 Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 2/105 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + + E +K D GA + + G ALHF + CA+ L+ GA V+ Sbjct: 111 LHVACEIANLECVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVLRGANVNMKT 170 Query: 354 KNKN--TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 N++ TPLH AA +G E V +++GA V N +TP+ +A Sbjct: 171 NNQDEETPLHTAAHFGLSELVAFYVENGAIVDSMNAHMETPLAIA 215 Score = 46.2 bits (108), Expect = 9e-05 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 2/114 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + +G E L LD A + G+ LH AC L+C +IL + GA ++ Sbjct: 79 LHLSVLLGHVECLMVLLDHNATINCRP-NGKTPLHVACEIANLECVKILCDRGAKLNCYS 137 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ--NLDGKTPIEVAKLNSQDEVV 199 + +T LH+ C L+ GA V ++ N D +TP+ A E+V Sbjct: 138 LSGHTALHFCTTPSSILCAKQLVLRGANVNMKTNNQDEETPLHTAAHFGLSELV 191 Score = 33.1 bits (74), Expect = 0.80 Identities = 20/51 (39%), Positives = 29/51 (56%) Frame = -3 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LH + G EC+ +LL H A + + +GKTP+ VA + E VK+L Sbjct: 77 TGLHLSVLLGHVECLMVLLDHNATINCRP-NGKTPLHVACEIANLECVKIL 126 Score = 31.2 bits (69), Expect = 3.0 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 7/79 (8%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 LD A + D + + LH A + ++LEAGA + +D N + Y Sbjct: 239 LDNNAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSV 298 Query: 306 E-------CVDLLLKHGAA 271 C LLL HGAA Sbjct: 299 RPAAQPEICYQLLLNHGAA 317
>ASB2_BOVIN (Q3SX45) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 633 Score = 54.7 bits (130), Expect = 3e-07 Identities = 36/110 (32%), Positives = 51/110 (46%), Gaps = 1/110 (0%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEA-GAAVDALDKNKNTPL 334 D E L + G N E + EG LH A YG+L C + L A A +D + T L Sbjct: 115 DEEALTAMIKAGKNLSEPNKEGWLPLHEAAYYGQLNCLKALHRAYPAVIDQRTLQEETAL 174 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + A G +C+ LL+ GA + N +TP+ A E V++L Q Sbjct: 175 YLATCRGHVDCLQFLLQAGAEPDISNKSRETPLYKACERKNVEAVRILVQ 224 Score = 52.8 bits (125), Expect = 1e-06 Identities = 30/115 (26%), Positives = 54/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + + D E ++ + GGA + ++ G L A G+L+ L + GA ++ Sbjct: 240 LHESVARNDLEVMEILVSGGAKVEAKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQA 299 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + L+ A G +E V+ LL GA N DG P+ +A +V++L Sbjct: 300 SDSASALYEACKNGHEEVVEFLLSQGADANKTNKDGMLPLHIASKKGNYRIVQML 354 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/86 (36%), Positives = 45/86 (52%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G ALH + +L+ EIL+ GA V+A + TPL AA G+ E + L K+GA + Sbjct: 236 GWTALHESVARNDLEVMEILVSGGAKVEAKNAYGITPLFVAAQSGQLEALRFLAKYGADI 295 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 Q D + + A N +EVV+ L Sbjct: 296 NTQASDSASALYEACKNGHEEVVEFL 321 Score = 43.1 bits (100), Expect = 8e-04 Identities = 26/92 (28%), Positives = 48/92 (52%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D+ ++ AL+ A G + C + LL+AGA D +K++ TPL+ A E V +L+ Sbjct: 164 DQRTLQEETALYLATCRGHVDCLQFLLQAGAEPDISNKSRETPLYKACERKNVEAVRILV 223 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ A + G T + + + EV+++L Sbjct: 224 QYKADTNHRCNRGWTALHESVARNDLEVMEIL 255 Score = 30.0 bits (66), Expect = 6.7 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Frame = -3 Query: 450 EGRR--ALHFACGYGELKCAEILLEAGAAVDALDKNKNT--PLHYAAGYGRKECVDLLLK 283 E RR AL+FA + E+LL AGA D N++ PL A +G + LLL Sbjct: 406 EDRRSSALYFAVVNNNVYATELLLLAGA-----DPNRDVINPLLVAIRHGCLRTMQLLLD 460 Query: 282 HGAAV 268 HGA + Sbjct: 461 HGANI 465
>MIB2_HUMAN (Q96AX9) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N) Length = 1013 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/99 (33%), Positives = 47/99 (47%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A +G E ++ L A D D EG ALH+A + + +LL AG DA++ ++ Sbjct: 531 AYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQS 590 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 T LH A G E V L + G V L + TP+ A Sbjct: 591 TALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA 629 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/87 (36%), Positives = 42/87 (48%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA 271 +GR AL A G+++ +LL+A A VD D NT LHYAA + E +LL G Sbjct: 522 QGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 581 Query: 270 VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 N T + VA EVV+ L Sbjct: 582 ADAINSTQSTALHVAVQRGFLEVVRAL 608 Score = 38.1 bits (87), Expect = 0.025 Identities = 31/108 (28%), Positives = 43/108 (39%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A E + L G D + ALH A G L+ L E G V+ D Sbjct: 560 LHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPD 619 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 + +TPLH A G GA+ +++ L I+V NSQ Sbjct: 620 AHSDTPLHSAISAGT----------GASGIVEVLTEVPNIDVTATNSQ 657
>ASZ1_HORSE (Q2QLA4) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/80 (41%), Positives = 43/80 (53%) Frame = -3 Query: 429 FACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD 250 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA MLQ D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKD 214 Query: 249 GKTPIEVAKLNSQDEVVKLL 190 GKTP E+AK N E+ L Sbjct: 215 GKTPSEIAKRNKHLEIFNFL 234 Score = 51.6 bits (122), Expect = 2e-06 Identities = 43/118 (36%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFAC---GYGE--LKCAEILLEAGAAVDAL 358 ASV + + ++ LD GA K D + + L AC G E LKC E+LL A + Sbjct: 87 ASVSNVDLVRVLLDRGA-KASFDKDKQTILITACSARGSEEQILKCVELLLSRNADPNVA 145 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ ++ V+KLLE Sbjct: 146 CRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203 Score = 37.0 bits (84), Expect = 0.055 Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 5/117 (4%) Frame = -3 Query: 486 LDGGANKDEEDV---EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 LD A K +E + E A G++ E LL++G +VD+ + TPL YAA Sbjct: 30 LDRAAQKLKEPLPIEEKNETFKRALTAGDVALVEELLDSGISVDSSFRYGWTPLMYAASV 89 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVA--KLNSQDEVVKLLEQDVFL*SKPSDP 151 + V +LL GA D +T + A S+++++K +E L S+ +DP Sbjct: 90 SNVDLVRVLLDRGAKASFDK-DKQTILITACSARGSEEQILKCVE---LLLSRNADP 142
>V231_FOWPV (Q9J504) Putative ankyrin repeat protein FPV231| Length = 256 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/102 (30%), Positives = 55/102 (53%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++H + +K L+ G + + D G ALH+A + ++LL +GA + Sbjct: 60 SVLHKAIGNNNITSVKLLLNHGIDYNLRDNHGYTALHYAITLQNREITDMLLSSGADPNI 119 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 ++ K+TPL++A Y R V+ L+ HGA + + + GKTP+ Sbjct: 120 MNNEKHTPLYHALLY-RSSNVESLILHGADINIVDDTGKTPL 160 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/96 (31%), Positives = 43/96 (44%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + D R LH A G + ++LL G + D + T LHYA +E Sbjct: 48 GADTNIVDKYNRSVLHKAIGNNNITSVKLLLNHGIDYNLRDNHGYTALHYAITLQNREIT 107 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D+LL GA + N + TP+ A L V L+ Sbjct: 108 DMLLSSGADPNIMNNEKHTPLYHALLYRSSNVESLI 143 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/102 (29%), Positives = 42/102 (41%) Frame = -3 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 K LD GA D + E L+ A + + L GA + +DK + LH A G Sbjct: 9 KMLLDYGARIDSRNKEECLPLNHAIATNNKELTSLFLARGADTNIVDKYNRSVLHKAIGN 68 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 V LLL HG L++ G T + A E+ +L Sbjct: 69 NNITSVKLLLNHGIDYNLRDNHGYTALHYAITLQNREITDML 110
>V018_FOWPV (Q9J5I3) Putative ankyrin repeat protein FPV018| Length = 700 Score = 54.3 bits (129), Expect = 3e-07 Identities = 37/111 (33%), Positives = 50/111 (45%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H +K + GAN +E D G L G++ E LL GA V+ D Sbjct: 433 IHLACMYSKIGNIKVLIKNGANVNERDNYGITPLMICSREGKVSNMEYLLANGADVNQTD 492 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEV 202 +KNT L YA KEC +LL+HGA + N TPI + K + V Sbjct: 493 YDKNTALTYAIRNKSKECTRVLLEHGADMCFMN-RFHTPITIHKTHDNPAV 542 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/115 (25%), Positives = 56/115 (48%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H S+ + + ++ GA+ + + G+ +H AC Y ++ ++L++ GA V+ D Sbjct: 400 IHAAVSINTSRLTRLLINKGADVNVRNRYGKTPIHLACMYSKIGNIKVLIKNGANVNERD 459 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL + G+ ++ LL +GA V + D T + A N E ++L Sbjct: 460 NYGITPLMICSREGKVSNMEYLLANGADVNQTDYDKNTALTYAIRNKSKECTRVL 514 Score = 33.5 bits (75), Expect = 0.61 Identities = 18/50 (36%), Positives = 27/50 (54%) Frame = -3 Query: 339 PLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 P+H A LL+ GA V ++N GKTPI +A + S+ +K+L Sbjct: 399 PIHAAVSINTSRLTRLLINKGADVNVRNRYGKTPIHLACMYSKIGNIKVL 448
>AKR1_ASPFU (Q4X251) Palmitoyltransferase akr1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein akr1) Length = 738 Score = 54.3 bits (129), Expect = 3e-07 Identities = 36/105 (34%), Positives = 51/105 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +I+H G+A L L D D +G L +A G C ++ L GA V+A Sbjct: 166 NILHLATIDGNAFLLVLLLHQEIPVDVIDQQGHTGLMWAAYKGYPACVDLFLRWGANVNA 225 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 +D TPLH+A G CV L+++GA + DGK+P VA Sbjct: 226 VDDGGLTPLHWALVKGSLPCVQKLIEYGADRFAKTRDGKSPATVA 270 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/101 (36%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L GA+ DV+G LH A G +LL VD +D+ +T L +AA G Sbjct: 151 LQHGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQEIPVDVIDQQGHTGLMWAAYKGYP 210 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKL-NSQDEVVKLLE 187 CVDL L+ GA V + G TP+ A + S V KL+E Sbjct: 211 ACVDLFLRWGANVNAVDDGGLTPLHWALVKGSLPCVQKLIE 251 Score = 38.5 bits (88), Expect = 0.019 Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNK-NTPLHYAAGYGRKECVDLLLK 283 +D EG LH+A + + LL+ GA V+A + TP +AA V LLL+ Sbjct: 93 QDEEGITPLHWAAINNQYAMCKFLLDNGADVNAKGGDSVATPAMWAAQRCHYYIVHLLLQ 152 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQD-EVVKLLEQDV 178 HGA +L ++ G + +A ++ +V LL Q++ Sbjct: 153 HGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQEI 188
>ASB2_HUMAN (Q96Q27) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 587 Score = 54.3 bits (129), Expect = 3e-07 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 1/111 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEA-GAAVDALDKNKNTP 337 GD E LK + G N E + EG LH A YG++ C ++L A +D + T Sbjct: 68 GDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETA 127 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 ++ A G +C+ LL+ GA + N +TP+ A E VK+L Q Sbjct: 128 VYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 178 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/115 (26%), Positives = 53/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + S D E ++ + GGA + ++ G L A G+L+ L + GA ++ Sbjct: 194 LHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQA 253 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + L+ A +E V+ LL GA N DG P+ +A +V++L Sbjct: 254 SDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQML 308 Score = 50.8 bits (120), Expect = 4e-06 Identities = 33/107 (30%), Positives = 54/107 (50%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 +AE +K + A+ + G ALH + +L+ +IL+ GA V++ + TPL Sbjct: 169 NAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLF 228 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 AA G+ E + L K+GA + Q D + + A N +EVV+ L Sbjct: 229 VAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFL 275 Score = 30.0 bits (66), Expect = 6.7 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Frame = -3 Query: 450 EGRR--ALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYGRKECVDLLLK 283 E RR AL+FA + E+LL+ GA D N++ +PL A +G + LLL Sbjct: 360 EDRRSSALYFAVVNNNVYATELLLQHGA-----DPNRDVISPLLVAIRHGCLRTMQLLLD 414 Query: 282 HGAAV 268 HGA + Sbjct: 415 HGANI 419
>ANR18_HUMAN (Q8IVF6) Ankyrin repeat domain-containing protein 18A| Length = 992 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/101 (34%), Positives = 55/101 (54%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ GAN + +D+ G ALH+A AE LL A ++AL+K NTPL +A R+ Sbjct: 121 LECGANPNIKDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQ 180 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 V+ LLK+ A + + +T + +A ++ +V LL Q Sbjct: 181 HMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQ 221 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGG-ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 +H A GDA +++ L + D D + R LH AC +G ++ +LL +D Sbjct: 38 IHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDIC 97 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D+ TPL A + C +LL+ GA ++++ G T + A N + + L Sbjct: 98 DRLNRTPLMKAVHSQEEACAIVLLECGANPNIKDIYGNTALHYAVYNKGTSLAERL 153 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/90 (28%), Positives = 40/90 (44%) Frame = -3 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 ++ L AN + + EG L FA E LL+ A + A+D K T L A + Sbjct: 151 ERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQH 210 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 V LLL+ + Q++ G+T + A Sbjct: 211 NLSSIVTLLLQQNIRISSQDMFGQTAEDYA 240
>TRPA1_CAEEL (Q18297) Transient receptor potential cation channel subfamily A| member 1 homolog Length = 1193 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/119 (29%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = -3 Query: 537 IVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-VDA 361 ++H A G E LK ++ G NK+E + LH A +L+ L+E +D Sbjct: 297 LIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYLIEEEKDNIDV 356 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEV-AKLNSQDEVVKLLE 187 +D+ TPL A + K+CV+ L+ A + + + D +TP+ + AK N+ V +L+ Sbjct: 357 VDEQGLTPLMMAVTHDSKKCVEYLIAKKANLTITDKDERTPVFIGAKFNALSSVEYILD 415 Score = 53.1 bits (126), Expect = 7e-07 Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 1/121 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G K LD GA+K+ ++ + L A G+L+ + L+ GA +++ Sbjct: 525 SALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPLQVAVDSGKLETCQRLVAKGAQIES 584 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQ 184 K T LH AA YG + V + G + ++ +GKT ++A N +V + LE Sbjct: 585 SSDTK-TVLHTAAFYGNESIVRYFIAEGVTIDRRDEEGKTAFDIACENDHKDVARAFLET 643 Query: 183 D 181 D Sbjct: 644 D 644 Score = 52.8 bits (125), Expect = 1e-06 Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Frame = -3 Query: 444 RRALHFACGYGELKCA-EILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 R +H + G + E LL+A AV+A D + TPLHYAA YG + V LLL A Sbjct: 33 RSIIHQSAREGNVNALQEALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALP 92 Query: 267 MLQNLDGKTPIEVAK--LNSQDEVVKLLEQD 181 +N +G TP+ +A + ++ ++++D Sbjct: 93 NTKNREGDTPLHIASKYIYGYSDICSIIDED 123 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 1/67 (1%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-L 193 V+ +D+++NTP+H A G E + LL KHGA++ N D +T + A + Q V+ L Sbjct: 449 VNMVDRDQNTPMHIVASNGYLEMMQLLQKHGASITQVNEDEETALHRAAIGGQTGAVRQL 508 Query: 192 LEQDVFL 172 LE D+ L Sbjct: 509 LEWDIRL 515 Score = 41.6 bits (96), Expect = 0.002 Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 24/139 (17%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFAC----GYGEL------------- 406 +H A G+ + +K L A + ++ EG LH A GY ++ Sbjct: 70 LHYAARYGNYDAVKLLLSKNALPNTKNREGDTPLHIASKYIYGYSDICSIIDEDQADSAR 129 Query: 405 -------KCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDG 247 K L+ A +D ++K + TPLHYAA + L+K A V ++ + Sbjct: 130 KYNTATKKIINALVSENAEIDPVNKYQLTPLHYAAMKSNFSALHALIKLKADVDAEDDNK 189 Query: 246 KTPIEVAKLNSQDEVVKLL 190 TP+ +A ++ E+++ L Sbjct: 190 MTPLLLACVHGSQEIIQEL 208 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKAL-DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 SI+H +A G+ L++AL + +D + LH+A YG ++LL A + Sbjct: 34 SIIHQSAREGNVNALQEALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALPN 93 Query: 363 ALDKNKNTPLHYAAGY 316 ++ +TPLH A+ Y Sbjct: 94 TKNREGDTPLHIASKY 109 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/88 (29%), Positives = 41/88 (46%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKH 280 +D G ALH A G ++LL+ GA +A + + TPL A G+ E L+ Sbjct: 519 KDEMGNSALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPLQVAVDSGKLETCQRLVAK 578 Query: 279 GAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 GA + + D KT + A + +V+ Sbjct: 579 GAQIE-SSSDTKTVLHTAAFYGNESIVR 605 Score = 39.7 bits (91), Expect = 0.009 Identities = 23/82 (28%), Positives = 39/82 (47%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 LH+A L++ A VDA D NK TPL A +G +E + L+K + V ++ Sbjct: 160 LHYAAMKSNFSALHALIKLKADVDAEDDNKMTPLLLACVHGSQEIIQELIKANSNVTKRD 219 Query: 255 LDGKTPIEVAKLNSQDEVVKLL 190 T + L + E ++++ Sbjct: 220 QRLNTVFHIVALRGEPEYLEMM 241 Score = 38.1 bits (87), Expect = 0.025 Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Frame = -3 Query: 444 RRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGA-AV 268 + +HFA G L+ + L+EAG + L++ K PLH AA + E V L++ + Sbjct: 295 KELIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYLIEEEKDNI 354 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + G TP+ +A + + V+ L Sbjct: 355 DVVDEQGLTPLMMAVTHDSKKCVEYL 380 Score = 34.7 bits (78), Expect = 0.27 Identities = 19/64 (29%), Positives = 29/64 (45%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N D D +G L A + KC E L+ A + DK++ TP+ A + V+ Sbjct: 353 NIDVVDEQGLTPLMMAVTHDSKKCVEYLIAKKANLTITDKDERTPVFIGAKFNALSSVEY 412 Query: 291 LLKH 280 +L H Sbjct: 413 ILDH 416
>ASZ1_OTOGA (Q2QLH1) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 53.9 bits (128), Expect = 4e-07 Identities = 44/118 (37%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFAC---GYGE--LKCAEILLEAGAAVDAL 358 ASV + E ++ LD GAN D + + L AC G E LKC E+LL A + Sbjct: 87 ASVANVELVRVLLDRGANASF-DKDKQTILITACSARGLEEQILKCVELLLSRNADPNVA 145 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ ++ V+KLLE Sbjct: 146 CRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/80 (40%), Positives = 42/80 (52%) Frame = -3 Query: 429 FACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD 250 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA MLQ D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKD 214 Query: 249 GKTPIEVAKLNSQDEVVKLL 190 GK P E+AK N E+ L Sbjct: 215 GKIPSEIAKRNKHLEIFNFL 234 Score = 34.3 bits (77), Expect = 0.36 Identities = 31/122 (25%), Positives = 57/122 (46%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G + + L G +E++ ++AL G++ + LL++G +VD+ + TP Sbjct: 27 IGYLDRASQKLKGPLPIEEKNETFKKALTT----GDISLVQELLDSGISVDSSFRYGWTP 82 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPS 157 L YAA E V +LL GA K I + +++ ++L+ L S+ + Sbjct: 83 LMYAASVANVELVRVLLDRGANASFDK--DKQTILITACSARGLEEQILKCVELLLSRNA 140 Query: 156 DP 151 DP Sbjct: 141 DP 142
>AKT5_ARATH (Q9SCX5) Probable potassium channel AKT5| Length = 880 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/86 (36%), Positives = 47/86 (54%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 +L FA G+ LL+ G+ + DKN T LH AA G + CV LLL+HGA ++ Sbjct: 545 SLCFAAARGDDLLLHQLLKRGSNPNETDKNGRTALHIAASKGSQYCVVLLLEHGADPNIR 604 Query: 258 NLDGKTPIEVAKLNSQDEVVKLLEQD 181 + +G P+ A + +E KLL ++ Sbjct: 605 DSEGSVPLWEAIIGRHEENAKLLSEN 630 Score = 49.7 bits (117), Expect = 8e-06 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 2/111 (1%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ GD L + L G+N +E D GR ALH A G C +LLE GA + D + Sbjct: 550 AARGDDLLLHQLLKRGSNPNETDKNGRTALHIAASKGSQYCVVLLLEHGADPNIRDSEGS 609 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK--LNSQDEVVK 196 PL A +E LL ++GA + + + + V + LN+ ++VK Sbjct: 610 VPLWEAIIGRHEENAKLLSENGATLSFDTVGYFSCLAVGQNNLNALKDIVK 660 Score = 33.1 bits (74), Expect = 0.80 Identities = 19/48 (39%), Positives = 24/48 (50%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 LK + G + DV G ALH A G L+ + LLE GA +D D Sbjct: 655 LKDIVKYGGDISLSDVNGTTALHRAVSEGNLEIVQFLLEKGADMDKPD 702
>AKR1_CANGA (Q6FJ70) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 763 Score = 53.5 bits (127), Expect = 6e-07 Identities = 41/137 (29%), Positives = 61/137 (44%), Gaps = 3/137 (2%) Frame = -3 Query: 648 QKIGEAMSLNFPVDAATSTVLSGPQXXXXXXXXXXESIVHNTASVGDAEGLKKALDGGAN 469 ++ G + +N D TS + G S HN GD E +++ + GG Sbjct: 26 REAGAGVEVNIANDNDTSVGVDGENGNEDDDPIL--SKYHNACQRGDLEVVREMIHGGQV 83 Query: 468 K--DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA-LDKNKNTPLHYAAGYGRKECV 298 + D EG LH+A L + L+ GA V++ + TPLH+AA YG V Sbjct: 84 NVSSDADREGVTGLHWAAINNRLNVVDFLVREGANVESKAGALEATPLHWAARYGFVYVV 143 Query: 297 DLLLKHGAAVMLQNLDG 247 D LL+HGA+ + G Sbjct: 144 DYLLQHGASATTTDKQG 160 Score = 37.0 bits (84), Expect = 0.055 Identities = 23/81 (28%), Positives = 38/81 (46%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D D +GR AL +A G+ L++ A+V D+ TPLH+ G+ + L+ Sbjct: 192 DYVDPKGRTALLWAAYQGDSLTVAALIKFNASVKIADEGGFTPLHWGTVKGQPHVLKYLI 251 Query: 285 KHGAAVMLQNLDGKTPIEVAK 223 + GA + D K +A+ Sbjct: 252 QDGADFFQKTNDNKDCFVIAE 272
>ASB2_MOUSE (Q8K0L0) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 634 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/107 (31%), Positives = 54/107 (50%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 +AE ++ + A+ + G ALH + +L+ EIL+ GA V+A + TPL Sbjct: 217 NAEAVRILVRYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLF 276 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 AA G+ E + L KHGA + Q D + + A N ++VV+ L Sbjct: 277 VAAQSGQLEALRFLAKHGADINTQASDSASALYEASKNEHEDVVEFL 323 Score = 52.0 bits (123), Expect = 2e-06 Identities = 35/109 (32%), Positives = 52/109 (47%), Gaps = 1/109 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEA-GAAVDALDKNKNTP 337 GD E LK + G N E + EG LH A YG+L C ++L +A +D + T Sbjct: 116 GDEEALKIMIQDGKNLAEPNKEGWLPLHEAAYYGQLGCLKVLQQAYPGTIDQRTLQEETA 175 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L+ A +C+ LL+ GA + N +TP+ A E V++L Sbjct: 176 LYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRIL 224 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/115 (26%), Positives = 54/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + S D E ++ + GGA + ++V L A G+L+ L + GA ++ Sbjct: 242 LHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQA 301 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + L+ A+ ++ V+ LL GA N DG P+ VA +V++L Sbjct: 302 SDSASALYEASKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGNYRIVQML 356 Score = 30.4 bits (67), Expect = 5.2 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Frame = -3 Query: 450 EGRR--ALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYGRKECVDLLLK 283 E RR AL+FA + E+LL AGA D N++ +PL A +G + LLL Sbjct: 408 EDRRSSALYFAVVNNNVYATELLLLAGA-----DPNRDVISPLLVAIRHGCLRTMQLLLD 462 Query: 282 HGAAV 268 HGA + Sbjct: 463 HGANI 467
>ASZ1_BOVIN (Q8WMX8) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 53.5 bits (127), Expect = 6e-07 Identities = 32/80 (40%), Positives = 43/80 (53%) Frame = -3 Query: 429 FACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD 250 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA M+Q D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMIQTKD 214 Query: 249 GKTPIEVAKLNSQDEVVKLL 190 GKTP E+AK N E+ L Sbjct: 215 GKTPSEIAKRNKHLEIFNFL 234 Score = 53.5 bits (127), Expect = 6e-07 Identities = 44/118 (37%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFAC---GYGE--LKCAEILLEAGAAVDAL 358 ASV + E ++ LD GAN D + + L AC G E LKC E+LL A + Sbjct: 87 ASVSNVELVRVLLDRGANASF-DKDKQTVLITACSARGSEEKILKCIELLLSRNADPNVA 145 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 + TP+ YAA G + V LL+ HGA V Q+ +G T + A+ ++ V+KLLE Sbjct: 146 CRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203
>PA2G6_HUMAN (O60733) 85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4)| (iPLA2) (CaI-PLA2) (Group VI phospholipase A2) (GVI PLA2) Length = 806 Score = 53.5 bits (127), Expect = 6e-07 Identities = 36/111 (32%), Positives = 52/111 (46%), Gaps = 4/111 (3%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 +AE + L G N + G ALH A CA +LL GA DA ++ NTPLH Sbjct: 296 NAEMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLH 355 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI----EVAKLNSQDEVVKLL 190 A E + L+ GA V N G+TP ++ +L ++ ++ LL Sbjct: 356 LAMSKDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLL 406
>FANK1_BOVIN (Q6B858) Fibronectin type 3 and ankyrin repeat domains protein 1| (GV14) Length = 345 Score = 53.5 bits (127), Expect = 6e-07 Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRA--LHFACGYGELKCAEILLEAGAAVDA 361 +H A G ++ + G D D R + + G + A +L++AGA V+ Sbjct: 214 LHWAADGGHCNVIEWMIGDGCEVDAVDAGSRWTPLMRVSAVSGNQEVASLLIDAGADVNV 273 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 DK+ TPL A +E V LLL GA ++N GK +E+A++ + V+ LLE+ Sbjct: 274 KDKDGKTPLMVAVLNNHEELVQLLLDRGADASVKNEFGKGVLEMARVFDRQNVLSLLEE 332 Score = 48.9 bits (115), Expect = 1e-05 Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 35/138 (25%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 +K + G + + ++ G+ +L AC G L + L GA+ D D T LH+AA Sbjct: 160 VKILISHGTDVNLQNGSGKDSLMLACYAGHLDVVKYLRRHGASWDTRDMGGCTALHWAAD 219 Query: 318 -----------------------------------YGRKECVDLLLKHGAAVMLQNLDGK 244 G +E LL+ GA V +++ DGK Sbjct: 220 GGHCNVIEWMIGDGCEVDAVDAGSRWTPLMRVSAVSGNQEVASLLIDAGADVNVKDKDGK 279 Query: 243 TPIEVAKLNSQDEVVKLL 190 TP+ VA LN+ +E+V+LL Sbjct: 280 TPLMVAVLNNHEELVQLL 297 Score = 34.7 bits (78), Expect = 0.27 Identities = 25/70 (35%), Positives = 32/70 (45%) Frame = -3 Query: 393 ILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 IL VD +K T L AA G V +L+ HG V LQN GK + +A Sbjct: 129 ILQGGNVKVDVPNKFGFTALMVAAQRGYTRLVKILISHGTDVNLQNGSGKDSLMLACYAG 188 Query: 213 QDEVVKLLEQ 184 +VVK L + Sbjct: 189 HLDVVKYLRR 198
>ASB1_MOUSE (Q9WV74) Ankyrin repeat and SOCS box protein 1 (ASB-1)| Length = 336 Score = 53.5 bits (127), Expect = 6e-07 Identities = 30/85 (35%), Positives = 50/85 (58%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ G + + GA D DV+G+ AL+ A G L+ EILLEAGA + +++ Sbjct: 87 ATAGHGNCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTEILLEAGADPNGSRHHRS 146 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAV 268 TP+++A+ GR + + L+++GA V Sbjct: 147 TPVYHASRVGRDDILKALIRYGADV 171 Score = 40.4 bits (93), Expect = 0.005 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 8/90 (8%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKN--------TPLHYAAGYGRKECVDLLLKH 280 LH A G+L+ LL+ + +++ TPL AA G CVD L++ Sbjct: 42 LHDAAYVGDLQTLRNLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGNCVDFLIRK 101 Query: 279 GAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 GA V L ++ G+T + VA +N E ++L Sbjct: 102 GAEVDLVDVKGQTALYVAVVNGHLESTEIL 131 Score = 31.6 bits (70), Expect = 2.3 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY-GRKECV-DLLLKHGAAVML 262 L+ + Y L+C +LL+AGA D N N P++ Y G CV D +L+HG Sbjct: 197 LYISAAYHNLQCFRLLLQAGANPDF---NCNGPVNTQEFYRGSPGCVMDAVLRHGCEAAF 253 Query: 261 QNL 253 +L Sbjct: 254 VSL 256
>AKT6_ARATH (Q8GXE6) Potassium channel AKT6 (Shaker pollen inward rectifier| K(+) channel) (Potassium channel SPIK) Length = 888 Score = 53.5 bits (127), Expect = 6e-07 Identities = 30/86 (34%), Positives = 47/86 (54%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 +L FA G+ LL G++ + +DK+ T LH AA G CV LLL+HGA ++ Sbjct: 547 SLCFAAARGDDLLLHQLLRRGSSPNEMDKDGRTALHIAASKGSHYCVVLLLEHGADPNIR 606 Query: 258 NLDGKTPIEVAKLNSQDEVVKLLEQD 181 + +G P+ A + E+ KLL ++ Sbjct: 607 DSEGNVPLWEAIIGRHREIAKLLAEN 632 Score = 52.0 bits (123), Expect = 2e-06 Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 2/111 (1%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ GD L + L G++ +E D +GR ALH A G C +LLE GA + D N Sbjct: 552 AARGDDLLLHQLLRRGSSPNEMDKDGRTALHIAASKGSHYCVVLLLEHGADPNIRDSEGN 611 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK--LNSQDEVVK 196 PL A +E LL ++GA + L ++ + + V K L++ +++K Sbjct: 612 VPLWEAIIGRHREIAKLLAENGAKLSLDSVSYFSGLAVEKNCLDALKDIIK 662
>TRPA1_DROME (Q7Z020) Transient receptor potential cation channel subfamily A| member 1 (Ankyrin-like with transmembrane domains protein 1) (dANKTM1) Length = 1197 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 +E+D G LH+A G ++ E L+ GA ++ + N +PLH+AA YGR V LL Sbjct: 438 NEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLL 497 Query: 285 KHGAAVMLQNLD---GKTPIEVAKLNSQDEVVKLL 190 + N G TP+ ++ VV+LL Sbjct: 498 DSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLL 532 Score = 46.2 bits (108), Expect = 9e-05 Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 3/120 (2%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA--- 370 S +H + G L+ + GA + ++ LHFA YG LL++ Sbjct: 446 SPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFI 505 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ D TPLH ++ G V LLL G A++ ++ G+ P+++A ++ E ++LL Sbjct: 506 INESDGAGMTPLHISSQQGHTRVVQLLLNRG-ALLHRDHTGRNPLQLAAMSGYTETIELL 564 Score = 40.0 bits (92), Expect = 0.007 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 8/94 (8%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAA--------VDALDKNKNTPLHYAAGYGRKECVDL 292 G +H A K E+ + G + D N PLH A G + V+L Sbjct: 225 GYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVEL 284 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LK GA + Q D TP+ +A ++VKL+ Sbjct: 285 CLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLM 318 Score = 37.4 bits (85), Expect = 0.042 Identities = 22/80 (27%), Positives = 38/80 (47%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 DV+ LH A + L+ GA ++ALDK +PL AA + V LL++ G Sbjct: 334 DVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAASRSGWKTVHLLIRLG 393 Query: 276 AAVMLQNLDGKTPIEVAKLN 217 A + +++ + + +N Sbjct: 394 ACISVKDAAARNVLHFVIMN 413 Score = 33.5 bits (75), Expect = 0.61 Identities = 20/78 (25%), Positives = 32/78 (41%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKH 280 +D +GR A H A + + + +A D NTPLH A + +D LL Sbjct: 86 KDAKGRTAAHQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSI 145 Query: 279 GAAVMLQNLDGKTPIEVA 226 + N + P+ +A Sbjct: 146 PVDTGVLNEKKQAPVHLA 163 Score = 31.2 bits (69), Expect = 3.0 Identities = 22/116 (18%), Positives = 47/116 (40%), Gaps = 2/116 (1%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 H A+ L+ D + + +D G LH A + LL L++ Sbjct: 95 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSIPVDTGVLNE 154 Query: 351 NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ--NLDGKTPIEVAKLNSQDEVVKLL 190 K P+H A + + + ++ ++ + +Q G+T + +A + +E ++L Sbjct: 155 KKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARIL 210
>ASB12_HUMAN (Q8WXK4) Ankyrin repeat and SOCS box protein 12 (ASB-12)| Length = 309 Score = 53.1 bits (126), Expect = 7e-07 Identities = 30/84 (35%), Positives = 46/84 (54%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 L A YG L C ++LL GA VD+LD TPL A +G +CV +LL+ GA+ Sbjct: 68 LRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSI 127 Query: 255 LDGKTPIEVAKLNSQDEVVKLLEQ 184 + +P+ A ++D V +L++ Sbjct: 128 YNNCSPVLTA---ARDGAVAILQE 148 Score = 50.1 bits (118), Expect = 6e-06 Identities = 35/103 (33%), Positives = 49/103 (47%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 AS G L+ L GA+ D DV+ + L A +G L C +LLEAGA+ N Sbjct: 72 ASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSIYNNC 131 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 +P+ AA G + LL HGA N+ K P+ + + S Sbjct: 132 SPVLTAARDGAVAILQELLDHGAEA---NVKAKLPVWASNIAS 171 Score = 38.1 bits (87), Expect = 0.025 Identities = 19/51 (37%), Positives = 29/51 (56%) Frame = -3 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL AA YG C+ +LL HGA V ++ +TP+ A + + V++L Sbjct: 66 TPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVL 116
>ASB2_RAT (Q5U2S6) Ankyrin repeat and SOCS box protein 2 (ASB-2)| Length = 634 Score = 53.1 bits (126), Expect = 7e-07 Identities = 34/107 (31%), Positives = 54/107 (50%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 +AE ++ + A+ + G ALH + +L+ EIL+ GA V+A + TPL Sbjct: 217 NAEAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLF 276 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 AA G+ E + L KHGA + Q D + + A N ++VV+ L Sbjct: 277 VAAQSGQLEALRFLAKHGADINTQASDSASALYEACKNEHEDVVEFL 323 Score = 52.8 bits (125), Expect = 1e-06 Identities = 36/111 (32%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEA-GAAVDALDKNKNTP 337 GD E LK + G N E + EG LH A YG+L C ++L A +D + T Sbjct: 116 GDEEALKAMIQDGKNLAEPNKEGWLPLHEAAYYGKLGCLKVLQRAYPGTIDQRTLQEETA 175 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 L+ A +C+ LL+ GA + N +TP+ A E V++L Q Sbjct: 176 LYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRILVQ 226 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/115 (26%), Positives = 53/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + S D E ++ + GGA + ++V L A G+L+ L + GA ++ Sbjct: 242 LHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQA 301 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + L+ A ++ V+ LL GA N DG P+ VA +V++L Sbjct: 302 SDSASALYEACKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGNYRIVQML 356 Score = 30.4 bits (67), Expect = 5.2 Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Frame = -3 Query: 450 EGRR--ALHFACGYGELKCAEILLEAGAAVDALDKNKN--TPLHYAAGYGRKECVDLLLK 283 E RR AL+FA + E+LL AGA D N++ +PL A +G + LLL Sbjct: 408 EDRRTSALYFAVVNNNVYATELLLLAGA-----DPNRDVISPLLVAIRHGCLRTMQLLLD 462 Query: 282 HGAAV 268 HGA + Sbjct: 463 HGANI 467
>ANR10_MOUSE (Q99LW0) Ankyrin repeat domain-containing protein 10| Length = 415 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVE-GRRALHFACGYGELKCAEILLEAGAAVDAL 358 VH A G E L + + GA+ + + H A G +C L++AGA ++ Sbjct: 61 VHWAAHFGKLECLMQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKP 120 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D TP+H AA G EC+ L+ GA L+N G T ++A+ E + L Sbjct: 121 DCEGETPIHKAARSGSLECITALVGSGAHTDLRNASGLTAADIAQTQGFQECTQFL 176 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/82 (31%), Positives = 37/82 (45%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDK 352 H A G + L + GAN ++ D EG +H A G L+C L+ +GA D + Sbjct: 96 HIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECITALVGSGAHTDLRNA 155 Query: 351 NKNTPLHYAAGYGRKECVDLLL 286 + T A G +EC LL Sbjct: 156 SGLTAADIAQTQGFQECTQFLL 177 Score = 35.0 bits (79), Expect = 0.21 Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (3%) Frame = -3 Query: 501 GLKKALDGGANKDEEDVEGRRALHFACGYGELK--CAEILLEAGAAVDALDKNKN-TPLH 331 G A++ G + EE + R LH AC G+L C+ + A + A D TP+H Sbjct: 4 GAGVAVEAGFSS-EELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVH 62 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLD-GKTPIEVAKLNSQDEVVKLLEQ 184 +AA +G+ EC+ L++ GA++ + +TP +A + + L Q Sbjct: 63 WAAHFGKLECLMQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQ 112
>V246_FOWPV (Q9J4Z4) Putative ankyrin repeat protein FPV246| Length = 592 Score = 52.8 bits (125), Expect = 1e-06 Identities = 36/116 (31%), Positives = 61/116 (52%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H G E + + G+ D +D G L ACG ++ +++L+E GA + + Sbjct: 293 LHAATRSGSVETVNALISYGSTVDIKDNIGSTPLMHACGNKDI--SKLLIEKGADPNISN 350 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN-LDGKTPIEVAKLNSQDEVVKLL 190 + TPLH AA YG + V+LLL +G ++ ++ + G TP++ E+VKLL Sbjct: 351 IHGYTPLHNAAAYGSVDVVNLLLSYGVSIDAKDKIIGSTPLDHGV--HHPEIVKLL 404 Score = 52.4 bits (124), Expect = 1e-06 Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKN-KNTP 337 G+ + K ++ GA+ + ++ G LH A YG + +LL G ++DA DK +TP Sbjct: 331 GNKDISKLLIEKGADPNISNIHGYTPLHNAAAYGSVDVVNLLLSYGVSIDAKDKIIGSTP 390 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQ 211 L + G E V LLL+ GA NL G TP++ A L S+ Sbjct: 391 LDH--GVHHPEIVKLLLEKGANPNTINLYGYTPLKNAILKSR 430 Score = 39.3 bits (90), Expect = 0.011 Identities = 25/75 (33%), Positives = 39/75 (52%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G + LL+ G V++ D TPLH A G E V+ L+ +G+ V +++ G TP+ Sbjct: 267 GYINVIHFLLDIGFNVNSFDSFGETPLHAATRSGSVETVNALISYGSTVDIKDNIGSTPL 326 Query: 234 EVAKLNSQDEVVKLL 190 A N ++ KLL Sbjct: 327 MHACGNK--DISKLL 339 Score = 35.8 bits (81), Expect = 0.12 Identities = 22/72 (30%), Positives = 38/72 (52%) Frame = -3 Query: 411 ELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE 232 ELK A++L+ GA +D ++ TPL G LLL +GA ++ +G T E Sbjct: 175 ELKIAQLLISRGAKLDIKNEYGYTPLRNTVINGNFALTKLLLDNGADASIK-CNGMTIFE 233 Query: 231 VAKLNSQDEVVK 196 ++ L+ +++K Sbjct: 234 ISTLSQNVDMIK 245
>DDFL1_MOUSE (Q5U464) Development and differentiation enhancing factor-like 1| Length = 904 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/91 (35%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Frame = -3 Query: 447 GRRALHFA---CGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 G ALH A + L + L++ G +DA + NT LH AA +G+ +C+ LLL+ Sbjct: 585 GELALHLAIRVASHASLPIVDFLIQNGGHLDAKAADGNTALHCAALHGQLDCLKLLLRGR 644 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 A V N G+T +++A+ E +LLEQ Sbjct: 645 APVGAVNDAGETALDIARNRQHKECEELLEQ 675 Score = 43.5 bits (101), Expect = 6e-04 Identities = 23/66 (34%), Positives = 34/66 (51%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 + G + D + +G ALH A +G+L C ++LL A V A++ T L A K Sbjct: 608 IQNGGHLDAKAADGNTALHCAALHGQLDCLKLLLRGRAPVGAVNDAGETALDIARNRQHK 667 Query: 306 ECVDLL 289 EC +LL Sbjct: 668 ECEELL 673
>ANKH_CHRVI (Q06527) Ankyrin homolog precursor| Length = 323 Score = 52.8 bits (125), Expect = 1e-06 Identities = 43/128 (33%), Positives = 63/128 (49%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A +GD E + LD GA+ D + G+ AL FA +L+ +LL GA V+A Sbjct: 40 AMIGDTETAAELLDQGAHVDAPNQFGKTALMFAVEGDDLETVALLLSRGADVNARTVAGC 99 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SK 163 TPL +AA G LLL+ GA V + G + +A S+ + ++EQ +F K Sbjct: 100 TPLTFAAEAGHIGISALLLERGAHVHDRTRSGWDALMIA---SRHGITDMVEQLLF---K 153 Query: 162 PSDPVLID 139 +DP D Sbjct: 154 GADPKAAD 161
>DDFL1_HUMAN (Q8TDY4) Development and differentiation enhancing factor-like 1| (Protein up-regulated in liver cancer 1) Length = 903 Score = 52.8 bits (125), Expect = 1e-06 Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 3/87 (3%) Frame = -3 Query: 435 LHFA---CGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVM 265 LH A L + +++ G +DA + NT LHYAA Y + +C+ LLLK A V Sbjct: 590 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 649 Query: 264 LQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 N G+T +++A+ E +LLEQ Sbjct: 650 TVNEAGETALDIARKKHHKECEELLEQ 676
>PA2G6_RAT (P97570) 85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4)| (iPLA2) (CaI-PLA2) (Group VI phospholipase A2) (GVI PLA2) Length = 751 Score = 52.8 bits (125), Expect = 1e-06 Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 1/101 (0%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 +AE + L G + D G ALH A C +LL GA A ++ NTPLH Sbjct: 295 NAEMARMLLKRGCDVDSTSASGNTALHVAVTRNRFDCVMVLLTYGANAGARGEHGNTPLH 354 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQ 211 A E V L+ GA V N G+TP +A K++ Q Sbjct: 355 LAMSKDNMEMVKALIVFGAEVDTPNDFGETPAFIASKISKQ 395 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/100 (31%), Positives = 48/100 (48%) Frame = -3 Query: 489 ALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 ++D ++ G LH+A + A +LL+ G VD+ + NT LH A R Sbjct: 272 SMDSNQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSASGNTALHVAVTRNR 328 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +CV +LL +GA + G TP+ +A E+VK L Sbjct: 329 FDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKAL 368
>ASZ1_MICMU (Q2QL84) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 481 Score = 52.4 bits (124), Expect = 1e-06 Identities = 32/80 (40%), Positives = 42/80 (52%) Frame = -3 Query: 429 FACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD 250 +A G + +L+ GA V+ D+N T L +AA G K V LL+ GA MLQ D Sbjct: 155 YAARDGHPQVVAVLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKD 214 Query: 249 GKTPIEVAKLNSQDEVVKLL 190 GK P E+AK N E+ L Sbjct: 215 GKIPSEIAKRNKHLEIFNFL 234 Score = 52.0 bits (123), Expect = 2e-06 Identities = 42/118 (35%), Positives = 62/118 (52%), Gaps = 6/118 (5%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFAC---GYGE--LKCAEILLEAGAAVDAL 358 AS+ + E ++ LD GAN D + + L AC G E LKC E+LL A + Sbjct: 87 ASIANVELVRVLLDRGANASF-DKDKQTILITACSARGSEEQILKCVELLLSRNADPNVA 145 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 + TP+ YAA G + V +L+ HGA V Q+ +G T + A+ ++ V+KLLE Sbjct: 146 CRRLMTPIMYAARDGHPQVVAVLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLE 203 Score = 36.2 bits (82), Expect = 0.094 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 2/90 (2%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G++ + LL++G +VD+ + TPL YAA E V +LL GA D +T + Sbjct: 57 GDISLVQELLDSGISVDSSFRYGWTPLMYAASIANVELVRVLLDRGANASFDK-DKQTIL 115 Query: 234 EVA--KLNSQDEVVKLLEQDVFL*SKPSDP 151 A S+++++K +E L S+ +DP Sbjct: 116 ITACSARGSEEQILKCVE---LLLSRNADP 142
>Y714_RICPR (Q9ZCL3) Hypothetical ANK-repeat protein RP714| Length = 107 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/80 (38%), Positives = 38/80 (47%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G+ E + L G + D D G ALH A G K A +LL GA +DA + TPL Sbjct: 19 GNIEYTSELLQNGVDIDVRDKNGNSALHIAASKGYTKIATMLLLYGATIDAPNFELATPL 78 Query: 333 HYAAGYGRKECVDLLLKHGA 274 HYAA K+ LL A Sbjct: 79 HYAAANNYKDLTQYLLNMNA 98 Score = 47.4 bits (111), Expect = 4e-05 Identities = 24/75 (32%), Positives = 39/75 (52%) Frame = -3 Query: 414 GELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 G ++ LL+ G +D DKN N+ LH AA G + +LL +GA + N + TP+ Sbjct: 19 GNIEYTSELLQNGVDIDVRDKNGNSALHIAASKGYTKIATMLLLYGATIDAPNFELATPL 78 Query: 234 EVAKLNSQDEVVKLL 190 A N+ ++ + L Sbjct: 79 HYAAANNYKDLTQYL 93
>AKR1_NEUCR (Q7S3M5) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 729 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L G D ED G AL ++ G C ++ L GA+V A D+ T LH+A G Sbjct: 164 LHQGIPVDVEDAYGHTALMWSAYKGFPACVDVFLRWGASVHAKDEQGFTALHWALVKGSP 223 Query: 306 ECVDLLLKHGAAVMLQNLDGKTP-IEVAKLNSQDEVVKLLEQ 184 C+ L+++GA + +GKTP I +LN+ K L++ Sbjct: 224 GCIQKLIEYGADRFAKTANGKTPAITAQELNTVAAWQKALDE 265 Score = 46.2 bits (108), Expect = 9e-05 Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 2/152 (1%) Frame = -3 Query: 639 GEAMSLNFPVDAATSTVLSGPQXXXXXXXXXXESIVHNTASVGDAEGLKKALDGGA-NKD 463 G A P+ + T+T + + + A VGD G++K G + Sbjct: 12 GHAAPAQPPMKSDTATPKLNSEVELGSLPSEAHNDIMQMARVGDITGMEKLFAAGEYDAT 71 Query: 462 EEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD-KNKNTPLHYAAGYGRKECVDLLL 286 D EG LH+A + + L++ GA ++ ++ TPL +AA V LLL Sbjct: 72 YSDDEGITPLHWAAINNQYAMCKFLIDKGAEINKKGGESVATPLQWAAQRCHYYTVHLLL 131 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +HGA ++ + G + ++ N ++ LL Sbjct: 132 QHGADPLITDSQGYNTLHISTFNGNVLLIVLL 163
>ASB1_HUMAN (Q9Y576) Ankyrin repeat and SOCS box protein 1 (ASB-1)| Length = 335 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/85 (34%), Positives = 50/85 (58%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A+ G + + GA D DV+G+ AL+ A G L+ +ILLEAGA + +++ Sbjct: 86 ATAGHGSCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLESTQILLEAGADPNGSRHHRS 145 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAV 268 TP+++A+ GR + + L+++GA V Sbjct: 146 TPVYHASRVGRADILKALIRYGADV 170 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 8/90 (8%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKN--------TPLHYAAGYGRKECVDLLLKH 280 LH A G+L+ LL+ + +++ TPL AA G CVD L++ Sbjct: 41 LHDAAYVGDLQTLRSLLQEESYRSRINEKSVWCCGWLPCTPLRIAATAGHGSCVDFLIRK 100 Query: 279 GAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 GA V L ++ G+T + VA +N E ++L Sbjct: 101 GAEVDLVDVKGQTALYVAVVNGHLESTQIL 130 Score = 33.9 bits (76), Expect = 0.47 Identities = 34/111 (30%), Positives = 51/111 (45%), Gaps = 17/111 (15%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEE-----DVEGRRA----------LHFACGYGELKC 400 V++ + VG A+ LK + GA+ D DV+ R + L+ + Y L+C Sbjct: 148 VYHASRVGRADILKALIRYGADVDVNHHLTPDVQPRFSRRLTSLVVCPLYISAAYHNLQC 207 Query: 399 AEILLEAGAAVDALDKNKNTPLHYAAGY-GRKECV-DLLLKHGAAVMLQNL 253 +LL AGA D N N P++ Y G CV D +L+HG +L Sbjct: 208 FRLLLLAGANPDF---NCNGPVNTQGFYRGSPGCVMDAVLRHGCEAAFVSL 255
>LITA_LATMA (Q02989) Alpha-latroinsectotoxin precursor (Alpha-LIT) (Fragment)| Length = 1411 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/136 (27%), Positives = 65/136 (47%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H ++ G+ + + + L A+ +G ALH + L+E GA V+ Sbjct: 741 LHLASATGNKQLVIELLAKNADVTRLTSKGFSALHLGIIGKNEEIPFFLVEKGANVNDKT 800 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVF 175 + TPLH+AAG G+ LLL GA + ++++ + PI A N E+V++L + Sbjct: 801 NSGVTPLHFAAGLGKANIFRLLLSRGADIKAEDINSQMPIHEAVSNGHLEIVRILIE--- 857 Query: 174 L*SKPSDPVLIDPKTL 127 DP L++ K + Sbjct: 858 -----KDPSLMNVKNI 868 Score = 50.4 bits (119), Expect = 5e-06 Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 ++ GAN +++ G LHFA G G+ +LL GA + A D N P+H A G Sbjct: 790 VEKGANVNDKTNSGVTPLHFAAGLGKANIFRLLLSRGADIKAEDINSQMPIHEAVSNGHL 849 Query: 306 ECVDLLLKHGAAVM-LQNLDGKTPIEVA 226 E V +L++ ++M ++N+ + P +A Sbjct: 850 EIVRILIEKDPSLMNVKNIRNEYPFYLA 877 Score = 43.5 bits (101), Expect = 6e-04 Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 2/101 (1%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGA-AVDALDKNKNTPLHYAAGYGR 310 + GAN E GR A+H A G E+LL ++ DKN TPLH AA + Sbjct: 487 IQNGANVSETFELGRGAIHAAASAGNYDVGELLLNKDINLLEKADKNGYTPLHIAADSNK 546 Query: 309 KECVDLLLKHGAAVMLQ-NLDGKTPIEVAKLNSQDEVVKLL 190 + V L+ + A V ++ D TP+ +A +V + L Sbjct: 547 NDFVMFLIGNNADVNVRTKSDLFTPLHLAARRDLTDVTQTL 587 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 2/91 (2%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 G LH A L +++L GA ++ D N TPLHYAA G E VD LL Sbjct: 635 GLTPLHLATLQNNLSVSKLLAGKGAYLNDGDANGMTPLHYAAMTGNLEMVDFLLNQQYIN 694 Query: 267 MLQNLDGK--TPIEVAKLNSQDEVVKLLEQD 181 + K TP+ +A L +++V + L D Sbjct: 695 INAATKEKKWTPLHLAILFKKNDVAERLLSD 725 Score = 31.6 bits (70), Expect = 2.3 Identities = 23/90 (25%), Positives = 35/90 (38%) Frame = -3 Query: 459 EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKH 280 +D G LH + A ++ A ++ K TPLH A LL Sbjct: 598 QDKSGFTPLHLSISSTSETAAILIRNTNAVINIKSKVGLTPLHLATLQNNLSVSKLLAGK 657 Query: 279 GAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 GA + + +G TP+ A + E+V L Sbjct: 658 GAYLNDGDANGMTPLHYAAMTGNLEMVDFL 687 Score = 31.6 bits (70), Expect = 2.3 Identities = 18/60 (30%), Positives = 31/60 (51%) Frame = -3 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++A DK+ TPLH + + L+ A + +++ G TP+ +A L + V KLL Sbjct: 595 LNAQDKSGFTPLHLSISSTSETAAILIRNTNAVINIKSKVGLTPLHLATLQNNLSVSKLL 654 Score = 30.0 bits (66), Expect = 6.7 Identities = 21/78 (26%), Positives = 31/78 (39%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 AN +E D G LH GEL+ + L++ GA + + T A GR V Sbjct: 894 ANVNEVDHNGNTLLHLFSSTGELEVVQFLMQNGANFRLKNNERKTFFDLAIENGRLNIVA 953 Query: 294 LLLKHGAAVMLQNLDGKT 241 ++ + GKT Sbjct: 954 FAVEKNKVNLQAAHRGKT 971
>ANKS1_HUMAN (Q92625) Ankyrin repeat and SAM domain-containing protein 1A (Odin)| Length = 1133 Score = 52.0 bits (123), Expect = 2e-06 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 3/118 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANK---DEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 +H A GDA+ ++ + G + +E++ + ALH A YG + ++LLE Sbjct: 116 LHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 175 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPL AA YGR E V +LL ++ N TP+ +A N VV++L Sbjct: 176 MRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVL 233 Score = 45.4 bits (106), Expect = 2e-04 Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 3/103 (2%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G N + D G LH A G E+LL A + D PLH AA G + V Sbjct: 69 GPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIV 128 Query: 297 DLLLKHGAA---VMLQNLDGKTPIEVAKLNSQDEVVKLLEQDV 178 LL+ G + V QN D +T + A EVVK+L +++ Sbjct: 129 RLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEEL 171 Score = 43.9 bits (102), Expect = 5e-04 Identities = 35/115 (30%), Positives = 49/115 (42%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E +K L+ + + + L A YG L+ ++LL A + + + Sbjct: 152 LHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCN 211 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K+TPLH AA G K V +LL G Q G E A D V LL Sbjct: 212 TKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 266
>ZDH13_PONPY (Q5NVB9) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) Length = 622 Score = 52.0 bits (123), Expect = 2e-06 Identities = 24/71 (33%), Positives = 47/71 (66%), Gaps = 1/71 (1%) Frame = -3 Query: 390 LLEAGAAVDALDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 LL+ +++ +DK ++NTPLH+A G VD LL+ G+++ +QN+ G+TP+++A N Sbjct: 202 LLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNK 261 Query: 213 QDEVVKLLEQD 181 ++ +L+ + Sbjct: 262 NQLIIHMLKTE 272 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/109 (32%), Positives = 52/109 (47%), Gaps = 1/109 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-TP 337 G E K+ ++ G + + D E LH+A L + + GA VD L + N TP Sbjct: 60 GIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTP 119 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH+A G V LLL+HGA L + +G + I +A L ++ L Sbjct: 120 LHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYL 168 Score = 32.3 bits (72), Expect = 1.4 Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 1/97 (1%) Frame = -3 Query: 426 ACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD- 250 A YG + + L+EAG V DK + LH+AA R + V + GA V D Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDL 115 Query: 249 GKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID 139 TP+ A +V LL Q +DP LID Sbjct: 116 NSTPLHWAIRQGHLPMVILLLQ------HGADPTLID 146
>ZDH13_MACFA (Q4R690) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) Length = 622 Score = 52.0 bits (123), Expect = 2e-06 Identities = 24/71 (33%), Positives = 47/71 (66%), Gaps = 1/71 (1%) Frame = -3 Query: 390 LLEAGAAVDALDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 LL+ +++ +DK ++NTPLH+A G VD LL+ G+++ +QN+ G+TP+++A N Sbjct: 202 LLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNK 261 Query: 213 QDEVVKLLEQD 181 ++ +L+ + Sbjct: 262 NQLIIHMLKTE 272 Score = 49.3 bits (116), Expect = 1e-05 Identities = 35/109 (32%), Positives = 52/109 (47%), Gaps = 1/109 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-TP 337 G E K+ ++ G + + D E LH+A L + + GA VD L + N TP Sbjct: 60 GIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTP 119 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH+A G V LLL+HGA L + +G + I +A L ++ L Sbjct: 120 LHWAIRQGHLPMVILLLQHGADPTLTDGEGFSSIHLAVLFQHMPIIAYL 168 Score = 30.4 bits (67), Expect = 5.2 Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 1/97 (1%) Frame = -3 Query: 426 ACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD- 250 A YG + + L+EAG V DK + LH+AA R + V + GA V D Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDL 115 Query: 249 GKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID 139 TP+ A +V LL Q +DP L D Sbjct: 116 NSTPLHWAIRQGHLPMVILLLQ------HGADPTLTD 146
>ZDH13_HUMAN (Q8IUH4) Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc| finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin-interacting protein HIP3RP) (Putativ Length = 622 Score = 52.0 bits (123), Expect = 2e-06 Identities = 24/71 (33%), Positives = 47/71 (66%), Gaps = 1/71 (1%) Frame = -3 Query: 390 LLEAGAAVDALDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 LL+ +++ +DK ++NTPLH+A G VD LL+ G+++ +QN+ G+TP+++A N Sbjct: 202 LLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNK 261 Query: 213 QDEVVKLLEQD 181 ++ +L+ + Sbjct: 262 NQLIIHMLKTE 272 Score = 48.1 bits (113), Expect = 2e-05 Identities = 35/109 (32%), Positives = 51/109 (46%), Gaps = 1/109 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN-TP 337 G E K+ ++ G + + D E LH+A L + GA VD L + N TP Sbjct: 60 GIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVRFYISKGAVVDQLGGDLNSTP 119 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LH+A G V LLL+HGA L + +G + I +A L ++ L Sbjct: 120 LHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYL 168 Score = 32.0 bits (71), Expect = 1.8 Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 1/97 (1%) Frame = -3 Query: 426 ACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD- 250 A YG + + L+EAG V DK + LH+AA R + V + GA V D Sbjct: 56 ATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVRFYISKGAVVDQLGGDL 115 Query: 249 GKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLID 139 TP+ A +V LL Q +DP LID Sbjct: 116 NSTPLHWAIRQGHLPMVILLLQ------HGADPTLID 146
>YL093_MIMIV (Q5UPG5) Putative ankyrin repeat protein L93| Length = 421 Score = 52.0 bits (123), Expect = 2e-06 Identities = 30/79 (37%), Positives = 45/79 (56%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E +K LD GA+ + + EG AL FAC Y ++ ++LL+ A ++A DK+ TPL +A Sbjct: 339 EIIKLLLDKGADINTGNGEGWTALMFACKYANIEAIKLLLDKNADINAKDKDGWTPLMFA 398 Query: 324 AGYGRKECVDLLLKHGAAV 268 Y E + LLL A + Sbjct: 399 CVYANIETIKLLLDKRADI 417 Score = 50.8 bits (120), Expect = 4e-06 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 4/109 (3%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGE----LKCAEILLEAGAAVDALDKNKNTP 337 E +K LD A+ + +D G AL AC Y ++ ++LL+ GA ++ + T Sbjct: 302 EAIKLLLDKNADINAKDKIGLTALMLACKYANTPNSIEIIKLLLDKGADINTGNGEGWTA 361 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L +A Y E + LLL A + ++ DG TP+ A + + E +KLL Sbjct: 362 LMFACKYANIEAIKLLLDKNADINAKDKDGWTPLMFACVYANIETIKLL 410 Score = 47.4 bits (111), Expect = 4e-05 Identities = 41/121 (33%), Positives = 57/121 (47%), Gaps = 8/121 (6%) Frame = -3 Query: 528 NTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGY----GELKCAEILLEAGAAVDA 361 NT S + + +K L+ G+N DE D G AL AC Y +K ++LL+ GA + Sbjct: 189 NTTS--NIKTVKLLLNRGSNIDELDNNGWTALMIACKYANTTSNIKTIKLLLDRGADTNI 246 Query: 360 LDKNKNTPLHYAAGYGRK----ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 DK T L A Y E + LLL GA + N +G T + A + E +KL Sbjct: 247 KDKIGLTALMLACKYANTPNSIEIIKLLLDKGADINTGNGEGWTALMFACKYANIEAIKL 306 Query: 192 L 190 L Sbjct: 307 L 307 Score = 34.7 bits (78), Expect = 0.27 Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 8/80 (10%) Frame = -3 Query: 405 KCAEILLEAGAAVDALDKNKNTPLHYAA----GYGRKECVDLLLKHGAAVMLQNLDGKTP 238 K +LL GA V+ + K T L A+ G + V LLL + A + + + DG T Sbjct: 84 KTVNLLLSKGAKVNLMKNEKQTVLMLASLNSRQIGSTDIVKLLLDYDAKIDISDEDGWTA 143 Query: 237 IEVAKLNSQDE----VVKLL 190 + A +NS + VKLL Sbjct: 144 LMYASINSNESSTIATVKLL 163
>AKR_ARATH (Q05753) Ankyrin repeat protein, chloroplast precursor (AKRP)| Length = 435 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 16/131 (12%) Frame = -3 Query: 528 NTASVGDAEGLKKALDG------------GANKDEEDVEGRRALHFACGYGELKCAEILL 385 N VG L +A+ G AN D EG +H+A ++LL Sbjct: 287 NATDVGGLTVLHRAIIGKKQAITNYLLRESANPFVLDDEGATLMHYAVQTASAPTIKLLL 346 Query: 384 EAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD- 208 A ++A D++ TPLH A R + V LLL GA + ++N DG TP+ + ++ Sbjct: 347 LYNADINAQDRDGWTPLHVAVQARRSDIVKLLLIKGADIEVKNKDGLTPLGLCLYLGREI 406 Query: 207 ---EVVKLLEQ 184 EV+KLL++ Sbjct: 407 RTYEVMKLLKE 417 Score = 46.6 bits (109), Expect = 7e-05 Identities = 34/115 (29%), Positives = 50/115 (43%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A+ G+ + L + + DV G LH A + LL A LD Sbjct: 264 LHTLAACGEFYLVDSLLKHNLDINATDVGGLTVLHRAIIGKKQAITNYLLRESANPFVLD 323 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T +HYA + LLL + A + Q+ DG TP+ VA + ++VKLL Sbjct: 324 DEGATLMHYAVQTASAPTIKLLLLYNADINAQDRDGWTPLHVAVQARRSDIVKLL 378 Score = 30.0 bits (66), Expect = 6.7 Identities = 20/78 (25%), Positives = 35/78 (44%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +++H A +K L A+ + +D +G LH A ++LL GA ++ Sbjct: 328 TLMHYAVQTASAPTIKLLLLYNADINAQDRDGWTPLHVAVQARRSDIVKLLLIKGADIEV 387 Query: 360 LDKNKNTPLHYAAGYGRK 307 +K+ TPL GR+ Sbjct: 388 KNKDGLTPLGLCLYLGRE 405
>AKR1_SACBA (Q876L5) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 763 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 4/90 (4%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGG---ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 H GD +K+ + G NKD + VE LH+A L + L+ GA V++ Sbjct: 77 HTACQKGDLATVKEMIHGKLLEVNKDGDSVEHITGLHWASINNRLSVVDFLVSQGADVNS 136 Query: 360 LDKNKN-TPLHYAAGYGRKECVDLLLKHGA 274 + TPLH+AA YG VD LLKHGA Sbjct: 137 RAGALHATPLHWAARYGYVYIVDFLLKHGA 166 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 5/107 (4%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAA-----VDALDKNKNTPLHYAA 322 L GA+ D +G LH + + +L + + VD D T L +AA Sbjct: 162 LKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFSVVSKGLLDVDCQDPKGRTSLLWAA 221 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 G V +LLK GA + + + +G TP+ + Q V+K L QD Sbjct: 222 YQGDSLTVAVLLKFGANIKIADTEGFTPLHWGTVKGQPHVLKYLIQD 268 Score = 38.1 bits (87), Expect = 0.025 Identities = 23/81 (28%), Positives = 39/81 (48%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 D +D +GR +L +A G+ +LL+ GA + D TPLH+ G+ + L+ Sbjct: 207 DCQDPKGRTSLLWAAYQGDSLTVAVLLKFGANIKIADTEGFTPLHWGTVKGQPHVLKYLI 266 Query: 285 KHGAAVMLQNLDGKTPIEVAK 223 + GA + GK +A+ Sbjct: 267 QDGADFFQKTDAGKDCFAIAQ 287
>PA2G6_MOUSE (P97819) 85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4)| (iPLA2) (CaI-PLA2) (Group VI phospholipase A2) (GVI PLA2) Length = 752 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 1/101 (0%) Frame = -3 Query: 510 DAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLH 331 +AE + L G + D G ALH A C +LL GA A ++ NTPLH Sbjct: 296 NAEMARMLLKRGCDVDSTSSSGNTALHVAVMRNRFDCVMVLLTYGANAGARGEHGNTPLH 355 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA-KLNSQ 211 A E V L+ GA V N G+TP +A K++ Q Sbjct: 356 LAMSKDNMEMVKALIVFGAEVDTPNDFGETPALIASKISKQ 396 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/100 (31%), Positives = 48/100 (48%) Frame = -3 Query: 489 ALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGR 310 ++D ++ G LH+A + A +LL+ G VD+ + NT LH A R Sbjct: 273 SMDSNQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSSSGNTALHVAVMRNR 329 Query: 309 KECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +CV +LL +GA + G TP+ +A E+VK L Sbjct: 330 FDCVMVLLTYGANAGARGEHGNTPLHLAMSKDNMEMVKAL 369
>CENB5_HUMAN (Q96P50) Centaurin-beta 5 (Cnt-b5)| Length = 759 Score = 51.6 bits (122), Expect = 2e-06 Identities = 41/119 (34%), Positives = 54/119 (45%), Gaps = 3/119 (2%) Frame = -3 Query: 537 IVHNTASVGDAEGLKKALDGGAN---KDEEDVEGRRALHFACGYGELKCAEILLEAGAAV 367 + H A D L AL GA D ED EG+ L A G L E LL+ GA V Sbjct: 596 LAHRAARARDLPALAAALAHGAEVNWADAED-EGKTPLVQAVLGGSLIVCEFLLQNGADV 654 Query: 366 DALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + D PLH+A GR V L LK GA + + + P+ +A + ++V LL Sbjct: 655 NQRDSRGRAPLHHATLLGRTGQVCLFLKRGADQHALDQEQRDPLAIAVQAANADIVTLL 713
>CENG2_HUMAN (Q9UPQ3) Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like,| ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1) Length = 857 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/58 (43%), Positives = 36/58 (62%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 +GR ALH AC G + A++L+ G V A D + NT L YA +EC+D+LL++G Sbjct: 768 DGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYG 825
>Y3287_PSEAE (Q9HYV6) Hypothetical ANK-repeat protein PA3287| Length = 171 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/110 (30%), Positives = 54/110 (49%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G A+ ++ L A+ D ++ G+ L A G+L E+LL GA V+ + T L Sbjct: 60 GHADTVRLLLAYKADPDLRNLAGQTPLAGAAFKGDLAMVELLLAGGADVEGASADGKTAL 119 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 AA + + E LL HGA Q+ G TP+ A++ + + V LL + Sbjct: 120 MMAAMFNQAEVAASLLAHGARRDAQDAAGLTPLAAARMMNAEATVALLSR 169 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/111 (31%), Positives = 52/111 (46%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A G+++ L++ L G + + +G L A +G +LL A D + Sbjct: 24 ARQGNSQRLEQLLQQGLPPNLRNHKGDSLLMLASYHGHADTVRLLLAYKADPDLRNLAGQ 83 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 TPL AA G V+LLL GA V + DGKT + +A + +Q EV L Sbjct: 84 TPLAGAAFKGDLAMVELLLAGGADVEGASADGKTALMMAAMFNQAEVAASL 134
>POTE2_HUMAN (Q6S8J3) Prostate, ovary, testis expressed protein on chromosome 2| (Fragment) Length = 712 Score = 51.2 bits (121), Expect = 3e-06 Identities = 38/115 (33%), Positives = 57/115 (49%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H ++ G++E +K LD + D + R AL A E +CA +LLE G + D Sbjct: 177 LHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPD 236 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + NT LHYA K LL +GA + +N G TP+ + + +VVK L Sbjct: 237 EYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFL 291 Score = 45.1 bits (105), Expect = 2e-04 Identities = 27/92 (29%), Positives = 43/92 (46%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 +++D + R ALH A G + ++LL+ ++ LD K T L A EC +LL Sbjct: 167 NKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLL 226 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +HG + + G T + A N + K L Sbjct: 227 EHGTDPNIPDEYGNTTLHYAIYNEDKLMAKAL 258 Score = 36.6 bits (83), Expect = 0.072 Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 1/104 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ G + + D G LH+A + A+ LL GA +++ +K+ TPL ++ Sbjct: 226 LEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQ 285 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQDV 178 + V L+K A + + G+T + +A +V LLEQ++ Sbjct: 286 QVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNI 329 Score = 34.3 bits (77), Expect = 0.36 Identities = 26/96 (27%), Positives = 44/96 (45%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + ++ G L + + + L++ A ++ALD+ T L A G V Sbjct: 262 GADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIV 321 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LLL+ V Q+L G+T E A + + +LL Sbjct: 322 SLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLL 357 Score = 32.3 bits (72), Expect = 1.4 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 1/83 (1%) Frame = -3 Query: 435 LHFACGYGELKCAE-ILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 LH A +G++ + I++ V+ DK K T LH A+ G E V LLL + + Sbjct: 143 LHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNVL 202 Query: 258 NLDGKTPIEVAKLNSQDEVVKLL 190 + +T + A +DE +L Sbjct: 203 DNKKRTALIKAVQCQEDECALML 225
>MIB2_CHICK (Q5ZIJ9) Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb| homolog 2) Length = 954 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/111 (32%), Positives = 56/111 (50%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKN 343 A++ +A +++ L +K + +GR AL A G L +ILL+A A V+ D+ + Sbjct: 440 AALNNAAKVRELLQKYPDKVDNKNQGRTALQIASYQGHLDVVKILLQAHATVNLRDEEGD 499 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 T LHYAA + + +L+ GA L N T + VA EVV+ L Sbjct: 500 TALHYAAFGNQADVARVLMAKGAGADLLNNAKCTALYVAVSQGFTEVVQAL 550 Score = 48.5 bits (114), Expect = 2e-05 Identities = 38/121 (31%), Positives = 60/121 (49%), Gaps = 2/121 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANK-DEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 +++H +A G+ +KK L D + +G ALH A + AEIL++ G Sbjct: 600 NLLHYSALKGNKLAIKKILARARQLVDSKKEDGFTALHLAALNNHKEVAEILIKEGRCDV 659 Query: 363 ALDKNKN-TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLE 187 + N+N TPLH A G V LL+ G+ V ++ DG T + +A L Q + L+E Sbjct: 660 NVKNNRNQTPLHLAIIQGHVGLVQLLVSEGSDVNAEDEDGDTAMHIA-LERQQLMSVLME 718 Query: 186 Q 184 + Sbjct: 719 K 719 Score = 32.3 bits (72), Expect = 1.4 Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 1/114 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A A+ + + GA D + AL+ A G + + L E V+ D Sbjct: 502 LHYAAFGNQADVARVLMAKGAGADLLNNAKCTALYVAVSQGFTEVVQALCELNCDVNLPD 561 Query: 354 KNKNTPLHYAAGYGRKECVDLLLK-HGAAVMLQNLDGKTPIEVAKLNSQDEVVK 196 + +TPLHYA K +++L + +QN G + + L +K Sbjct: 562 SHGDTPLHYAITADYKVIIEILTEVPNIDFTVQNCQGFNLLHYSALKGNKLAIK 615
>VB04_VACCV (P24769) Ankyrin repeat protein B4| Length = 558 Score = 51.2 bits (121), Expect = 3e-06 Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 2/113 (1%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGY--GELKCAEILLEAGAAVDALDKNKNTPLH 331 E +K L+ G++ D++D G C + ++ EI LE A +D++D N+ TPLH Sbjct: 191 ELIKILLNNGSDVDKKDTYGNTPFILLCKHDINNVELFEICLE-NANIDSVDFNRYTPLH 249 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL 172 Y + + + V LL+ GA V +N G TP ++ + LE D L Sbjct: 250 YVSCRNKYDFVKLLISKGANVNARNRFGTTPFYCGIIHGISLIKLYLESDTEL 302
>VB04_VACCC (P21001) Ankyrin repeat protein B4| Length = 558 Score = 51.2 bits (121), Expect = 3e-06 Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 2/113 (1%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGY--GELKCAEILLEAGAAVDALDKNKNTPLH 331 E +K L+ G++ D++D G C + ++ EI LE A +D++D N+ TPLH Sbjct: 191 ELIKILLNNGSDVDKKDTYGNTPFILLCKHDINNVELFEICLE-NANIDSVDFNRYTPLH 249 Query: 330 YAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL 172 Y + + + V LL+ GA V +N G TP ++ + LE D L Sbjct: 250 YVSCRNKYDFVKLLISKGANVNARNKFGTTPFYCGIIHGISLIKLYLESDTEL 302
>EHMT2_HUMAN (Q96KQ7) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1210 Score = 51.2 bits (121), Expect = 3e-06 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E L GAN + D + R L A L+ A +++ G V + + Sbjct: 689 LHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKE 748 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ +T LH+AA G E V LLL G V Q+ G TPI A + EV+++L Sbjct: 749 EDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRML 804 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/88 (36%), Positives = 45/88 (51%) Frame = -3 Query: 504 EGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 E ++ L GA+ D E LH+A G AE+LL A + A++ + +TPLH A Sbjct: 799 EVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 858 Query: 324 AGYGRKECVDLLLKHGAAVMLQNLDGKT 241 A +CV L L GA L+N +G T Sbjct: 859 ARESYHDCVLLFLSRGANPELRNKEGDT 886 Score = 47.4 bits (111), Expect = 4e-05 Identities = 29/94 (30%), Positives = 44/94 (46%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + R LH A G ++ +LL+AGA ++A+DK + TPL A E Sbjct: 677 NFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARY 736 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +++ G V + DG T + A E+V LL Sbjct: 737 MVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 770 Score = 44.7 bits (104), Expect = 3e-04 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 1/115 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGG-ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 +H+ A +G+ E + L G + + +D G + +A + ++ +LL GA V Sbjct: 755 LHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLT 814 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 D +N LH+A+ G ++LL + N G TP+ +A S + V L Sbjct: 815 DNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLL 869 Score = 39.7 bits (91), Expect = 0.009 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Frame = -3 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALDKN-------KNTPLHYAAGYGRKECVDLLLK 283 R L+ + GEL+ ++L +D LD N K TPLH AA G E +LL+ Sbjct: 652 RQLYLSVKQGELQKVILML-----LDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQ 706 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 GA + + +TP+ A +N+ EV + + Q Sbjct: 707 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 739
>PSDA_YEAST (P50086) Probable 26S proteasome regulatory subunit p28 (Proteasome| non-ATPase subunit 6) Length = 228 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/117 (32%), Positives = 54/117 (46%), Gaps = 3/117 (2%) Frame = -3 Query: 531 HNTASVGDAEGLKKALDGGANKDEEDV--EGRRALHFACGYGELKCAEILLEAGAAVDAL 358 H SVG+ E +K D D + +G LH A G + ++ L+E GA+V Sbjct: 77 HIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIK 136 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHG-AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 DK PLH AA G + ++LL G +AV Q+ G TP+ A + LL Sbjct: 137 DKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLL 193
>ANKR7_HUMAN (Q92527) Ankyrin repeat domain-containing protein 7| (Testis-specific protein TSA806) Length = 201 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/71 (42%), Positives = 40/71 (56%) Frame = -3 Query: 402 CAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 CA ILL GA D D NT LHYA V+ LL++ A + +N DG TP+ VA Sbjct: 54 CATILLNFGADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAV 113 Query: 222 LNSQDEVVKLL 190 +N+ ++VK L Sbjct: 114 INNNPKMVKFL 124 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/101 (32%), Positives = 48/101 (47%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ GA+ D D+ LH+A L E LLE A ++A +K+ TPL A Sbjct: 59 LNFGADPDLRDIRYNTVLHYAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNP 118 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 + V LL+ GA V + +T + +A +VKLL Q Sbjct: 119 KMVKFLLEKGADVNASDNYQRTALILAVSGEPPCLVKLLLQ 159 Score = 30.4 bits (67), Expect = 5.2 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 1/83 (1%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 ++K L+ A+ + ++ +G L A K + LLE GA V+A D + T L A Sbjct: 88 VEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMVKFLLEKGADVNASDNYQRTALILAVS 147 Query: 318 YGRKEC-VDLLLKHGAAVMLQNL 253 G C V LLL+ G + + + Sbjct: 148 -GEPPCLVKLLLQQGVELCYEGI 169
>YMV8_YEAST (Q04749) Hypothetical 47.1 kDa protein in NCA1-HMS1 intergenic| region Length = 426 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 GR +H AC +C +L+ GA + +D N +TPLH YG C+ +LL G Sbjct: 109 GRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVS 168 Query: 267 MLQNLDGK---TPIEVAK 223 + N+ K PI+VA+ Sbjct: 169 LDDNVRDKGNWKPIDVAQ 186 Score = 33.1 bits (74), Expect = 0.80 Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAA-VDALDKNKNTPLHYAAGYGRKECVDLLLKHGA 274 +G +H A G + +LL+ ++ +N P+H A +C+ LL+ GA Sbjct: 74 KGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGA 133 Query: 273 AVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + + +G TP+ V +K+L Sbjct: 134 DLWVMDTNGDTPLHVCLEYGSISCMKML 161
>CENG2_MOUSE (Q8BXK8) Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like,| ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) Length = 857 Score = 50.8 bits (120), Expect = 4e-06 Identities = 25/58 (43%), Positives = 36/58 (62%) Frame = -3 Query: 450 EGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 +GR ALH AC G + A++L+ G V A D + NT L YA +EC+D+LL++G Sbjct: 768 DGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECIDVLLQYG 825
>V155_FOWPV (Q9J5A7) Putative ankyrin repeat protein FPV115| Length = 542 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/115 (30%), Positives = 61/115 (53%), Gaps = 3/115 (2%) Frame = -3 Query: 525 TASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEA---GAAVDALD 355 T + +A+ L ++ G + + +D +G+ ALH+AC + C E + E GA ++ D Sbjct: 226 TIQLYNADMLLFLIEIGLDINTKDKKGKTALHYACN--SINCIETVKEIMKYGADINVKD 283 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + TPLH A YG + LL+++GA V ++ T + +A + E+VK L Sbjct: 284 REGLTPLHSACKYGDLKLSKLLIEYGADVKVKTT--STVLNLAVESGNVELVKFL 336 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/79 (36%), Positives = 45/79 (56%) Frame = -3 Query: 519 SVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 S+ E +K+ + GA+ + +D EG LH AC YG+LK +++L+E GA D K +T Sbjct: 262 SINCIETVKEIMKYGADINVKDREGLTPLHSACKYGDLKLSKLLIEYGA--DVKVKTTST 319 Query: 339 PLHYAAGYGRKECVDLLLK 283 L+ A G E V L++ Sbjct: 320 VLNLAVESGNVELVKFLIE 338 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/89 (30%), Positives = 44/89 (49%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 +L A ++ +LL+AG V++ K +TPLH G V LLL HGA + Sbjct: 350 SLSLAIRCKDINIVLLLLDAGMDVNS-SKCISTPLHLGVILGNSNIVKLLLDHGANINAI 408 Query: 258 NLDGKTPIEVAKLNSQDEVVKLLEQDVFL 172 + G+TP+E A + +L + + F+ Sbjct: 409 DKYGETPLEAANKRINIDYAELYKSNRFI 437 Score = 31.6 bits (70), Expect = 2.3 Identities = 20/50 (40%), Positives = 29/50 (58%) Frame = -3 Query: 411 ELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVML 262 EL ++LL GA ++ K+ PL++AA G E V+LLL +GA L Sbjct: 138 ELCIMDLLLRYGALPNSR-KDGLLPLYHAAAAGNTEMVELLLSYGAKTNL 186
>PME5_CAEEL (Q9TXQ1) Poly(ADP-ribose) polymerase pme-5 (EC 2.4.2.30) (Poly| ADP-ribose metabolism enzyme 5) Length = 2276 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -3 Query: 435 LHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQN 256 L ACG G L+ A+ L+E GA V+ DK K TPL +A G+ LL GA++ L + Sbjct: 503 LMMACGKGYLEMAKKLVEKGALVEGKDKKKRTPLIHAMLNGQIHTAAFLLAKGASLTLAD 562 Query: 255 LDGKTPIEVAKLNSQDEVVKLLEQ-DVFL*SKPSD 154 G T A + +KLL D + S+P+D Sbjct: 563 SSGNTAAHYAAAYGFLDCLKLLASIDDNILSEPND 597 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 1/109 (0%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E KK ++ GA + +D + R L A G++ A LL GA++ D + NT Sbjct: 510 GYLEMAKKLVEKGALVEGKDKKKRTPLIHAMLNGQIHTAAFLLAKGASLTLADSSGNTAA 569 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKT-PIEVAKLNSQDEVVKLL 190 HYAA YG +C+ LL ++ + D + P+ VA L +V L Sbjct: 570 HYAAAYGFLDCLKLLASIDDNILSEPNDWQLYPLSVAYLKGHYGIVTWL 618 Score = 39.7 bits (91), Expect = 0.009 Identities = 19/40 (47%), Positives = 23/40 (57%) Frame = -3 Query: 405 KCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 KC L++AGA VD D NTPLHYA G +L+L Sbjct: 711 KCFNTLIKAGAKVDVYDHEDNTPLHYALTNGNLMLFNLML 750 Score = 35.4 bits (80), Expect = 0.16 Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILL-EAGAAVD---ALDKNKNTPLHYAAGYGRKECVDLLLKH 280 G ALH A L + LL E VD + +N+ TPL A G G E L++ Sbjct: 462 GNSALHLAVLRNNLDVVDALLAEPTIVVDNPTSTGQNRLTPLMMACGKGYLEMAKKLVEK 521 Query: 279 GAAVMLQNLDGKTPIEVAKLNSQ 211 GA V ++ +TP+ A LN Q Sbjct: 522 GALVEGKDKKKRTPLIHAMLNGQ 544 Score = 35.0 bits (79), Expect = 0.21 Identities = 29/96 (30%), Positives = 41/96 (42%), Gaps = 16/96 (16%) Frame = -3 Query: 465 DEEDVEGRRALHFACG-----------YGELKCAEIL-----LEAGAAVDALDKNKNTPL 334 D D R ALH+A G +GE ++ L ++ D N NT L Sbjct: 1117 DAVDKFNRTALHYAFGNENDFKEGNVPFGESDPIAVVSLLSSLIRPEQIEIADVNGNTIL 1176 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 H AA C+ L++ V L+N DG TP+ +A Sbjct: 1177 HLAAIKNSTICLMTLIRKKCHVDLKNKDGNTPLALA 1212 Score = 34.7 bits (78), Expect = 0.27 Identities = 21/63 (33%), Positives = 28/63 (44%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 DV G LH A C L+ VD +K+ NTPL A +GR+ L++ Sbjct: 1169 DVNGNTILHLAAIKNSTICLMTLIRKKCHVDLKNKDGNTPLALAVHHGRQSSALTLIQAN 1228 Query: 276 AAV 268 A V Sbjct: 1229 ADV 1231 Score = 32.7 bits (73), Expect = 1.0 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 7/81 (8%) Frame = -3 Query: 540 SIVHNTASVGDAE--GLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEIL-----LE 382 S+ H A V + GL K ++ + E + +GR LH A + +L L Sbjct: 1052 SVWHYAARVNSHKTVGLFKMIESKGVRRETNDDGRSVLHVATLACDGSADSVLEPIAWLS 1111 Query: 381 AGAAVDALDKNKNTPLHYAAG 319 +DA+DK T LHYA G Sbjct: 1112 TRCPIDAVDKFNRTALHYAFG 1132 Score = 32.3 bits (72), Expect = 1.4 Identities = 20/58 (34%), Positives = 26/58 (44%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLK 283 D + +H+A E LL+ G +V L K TPLH AA GR L+K Sbjct: 376 DQDNWYTMHYAACAPGTAPMEFLLKNGGSVTMLTKQTETPLHVAARAGRAVNCTFLMK 433
>NOTC3_HUMAN (Q9UM47) Neurogenic locus notch homolog protein 3 precursor (Notch 3)| [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain] Length = 2321 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D G+ ALH+A ++ LL+ GA D D + TPL AA G E Sbjct: 1930 ADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAK 1989 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LLL H A + + + P +VA+ ++V+LL+Q Sbjct: 1990 LLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ 2026 Score = 45.8 bits (107), Expect = 1e-04 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = -3 Query: 528 NTASVGDAEGLKKAL--DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +TA DA+G+ + L + + D +G AL A E L+ + A V+A+D Sbjct: 1877 HTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1936 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + LH+AA E LLK+GA +Q+ +TP+ +A E KLL Sbjct: 1937 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLL 1991 Score = 40.0 bits (92), Expect = 0.007 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A Y A+ LL+AGA +A D + TPLH A + +L+++ Sbjct: 1836 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNR 1895 Query: 276 AAVM-LQNLDGKTPIEVA 226 + + + DG T + +A Sbjct: 1896 STDLDARMADGSTALILA 1913 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Frame = -3 Query: 390 LLEAGAAVDA-LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 L+ GA + A D+ T LH AA Y R + LL GA Q+ G+TP+ A Sbjct: 1824 LICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTAD 1883 Query: 213 QDEVVKLL 190 V ++L Sbjct: 1884 AQGVFQIL 1891
>CMTA3_ARATH (Q8GSA7) Calmodulin-binding transcription activator 3| (Signal-responsive protein 1) (Ethylene-induced calmodulin-binding protein a) (EICBP.a) (Ethylene-induced calmodulin-binding protein 1) (EICBP1) Length = 1032 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/111 (33%), Positives = 52/111 (46%), Gaps = 6/111 (5%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 L+K +GG D G+ LHFA G E + AG +VD D N T LH+AA Sbjct: 645 LQKIAEGGKGPSVLDEGGQGVLHFAASLGYNWALEPTIIAGVSVDFRDVNGWTALHWAAF 704 Query: 318 YGRKECVDLLLKHGAA---VMLQNLD---GKTPIEVAKLNSQDEVVKLLEQ 184 +GR+ + L+ GAA + N D G TP ++A N + L + Sbjct: 705 FGRERIIGSLIALGAAPGTLTDPNPDFPSGSTPSDLAYANGHKGIAGYLSE 755 Score = 37.0 bits (84), Expect = 0.055 Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 8/106 (7%) Frame = -3 Query: 537 IVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 ++H AS+G L+ + G + D DV G ALH+A +G + L+ GAA L Sbjct: 665 VLHFAASLGYNWALEPTIIAGVSVDFRDVNGWTALHWAAFFGRERIIGSLIALGAAPGTL 724 Query: 357 -DKNK-----NTPLHYAAGYGRKECVDLLLKHG--AAVMLQNLDGK 244 D N +TP A G K L ++ A V L +L+ K Sbjct: 725 TDPNPDFPSGSTPSDLAYANGHKGIAGYLSEYALRAHVSLLSLNDK 770
>NOTC3_RAT (Q9R172) Neurogenic locus notch homolog protein 3 precursor (Notch 3)| [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain] Length = 2319 Score = 50.4 bits (119), Expect = 5e-06 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D G+ ALH+A ++ LL+ GA D D + TPL AA G E Sbjct: 1932 ADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAK 1991 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LLL H A + + + P +VA+ ++V+LL+Q Sbjct: 1992 LLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQ 2028 Score = 45.8 bits (107), Expect = 1e-04 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = -3 Query: 528 NTASVGDAEGLKKAL--DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +TA DA+G+ + L + + D +G AL A E L+ + A V+A+D Sbjct: 1879 HTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1938 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + LH+AA E LLK+GA +Q+ +TP+ +A E KLL Sbjct: 1939 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLL 1993 Score = 40.0 bits (92), Expect = 0.007 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A Y A+ LL+AGA +A D + TPLH A + +L+++ Sbjct: 1838 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNR 1897 Query: 276 AAVM-LQNLDGKTPIEVA 226 + + + DG T + +A Sbjct: 1898 STDLDARMADGSTALILA 1915 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Frame = -3 Query: 390 LLEAGAAVDA-LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 L+ GA + A D+ T LH AA Y R + LL GA Q+ G+TP+ A Sbjct: 1826 LICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTAD 1885 Query: 213 QDEVVKLL 190 V ++L Sbjct: 1886 AQGVFQIL 1893
>ASB15_BOVIN (Q8HXA6) Ankyrin repeat and SOCS box protein 15 (ASB-15)| Length = 588 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/117 (30%), Positives = 51/117 (43%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G + + L+ G N +D G L A YG E L+ G V A Sbjct: 179 SAMHEAAKQGHKDIIALLLNNGGNVHLKDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVLA 238 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 L + + L AAG G +C+ LLL++G + + N G PI A +K L Sbjct: 239 LADDGASVLFEAAGGGNPDCISLLLEYGGSGNIPNRAGHLPIHRAAYEGHYLALKYL 295 Score = 39.7 bits (91), Expect = 0.009 Identities = 27/96 (28%), Positives = 46/96 (47%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G E ++ L+ G + ++ +G L A G LL+ ++D + + + Sbjct: 122 GLVENVRTLLEKGVWPNTKNDKGETPLLLAIKRGSYDMVSALLKHNTSLDQPCVKRWSAM 181 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 H AA G K+ + LLL +G V L++ G TP+ VA Sbjct: 182 HEAAKQGHKDIIALLLNNGGNVHLKDGFGVTPLGVA 217 Score = 36.6 bits (83), Expect = 0.072 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 12/101 (11%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGAN---------KDEEDVEGRRALHFACGYGELKCAEILLE 382 +H+ A +A+ L+ ++ G + + D E + AL+FA ++ C EILL Sbjct: 312 IHSAADGQNAQCLELLIENGFDVNSLLADHISESYDDERKTALYFAVCNNDILCTEILLA 371 Query: 381 AGAAVDALDKNKNTPLH---YAAGYGRKECVDLLLKHGAAV 268 AGA D N + PL+ A E V LLL HGA V Sbjct: 372 AGA-----DPNLD-PLNCLLVAVRANNHEIVRLLLAHGANV 406 Score = 34.3 bits (77), Expect = 0.36 Identities = 28/108 (25%), Positives = 44/108 (40%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPL 334 G + + L + D+ V+ A+H A G +LL G V D TPL Sbjct: 155 GSYDMVSALLKHNTSLDQPCVKRWSAMHEAAKQGHKDIIALLLNNGGNVHLKDGFGVTPL 214 Query: 333 HYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 AA YG + ++ L+ G V+ DG + + A + + LL Sbjct: 215 GVAAEYGHCDVLEHLIHKGGDVLALADDGASVLFEAAGGGNPDCISLL 262 Score = 33.9 bits (76), Expect = 0.47 Identities = 21/88 (23%), Positives = 43/88 (48%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S++ A G+ + + L+ G + + + G +H A G + L+ + A Sbjct: 245 SVLFEAAGGGNPDCISLLLEYGGSGNIPNRAGHLPIHRAAYEGHYLALKYLIPV-TSKHA 303 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHG 277 + K+ TP+H AA +C++LL+++G Sbjct: 304 IQKSGLTPIHSAADGQNAQCLELLIENG 331 Score = 32.7 bits (73), Expect = 1.0 Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 3/101 (2%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAV--DALDKNKNTPLHYAAGYGRKECVDL 292 DE D +G LH A + E++L+A + + TPL A G E V Sbjct: 70 DEADEKGWFPLHEAVVQPIQQILEVVLDASYKTLWEFKTSDGETPLTLAVKAGLVENVRT 129 Query: 291 LLKHGAAVMLQNLDGKTPIEVA-KLNSQDEVVKLLEQDVFL 172 LL+ G +N G+TP+ +A K S D V LL+ + L Sbjct: 130 LLEKGVWPNTKNDKGETPLLLAIKRGSYDMVSALLKHNTSL 170
>HOS4_YEAST (P40480) Protein HOS4| Length = 1083 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/97 (34%), Positives = 55/97 (56%), Gaps = 3/97 (3%) Frame = -3 Query: 513 GDAEGLKKALD-GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD--ALDKNKN 343 G + +KK ++ GG + +++D G ALH A G ++ E+L+E GA V+ +++ + Sbjct: 341 GKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGD 400 Query: 342 TPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE 232 TPL A+ G + V LLK+GA ++N G T E Sbjct: 401 TPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFE 437 Score = 32.0 bits (71), Expect = 1.8 Identities = 18/38 (47%), Positives = 21/38 (55%) Frame = -3 Query: 438 ALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYA 325 AL A G G L ++LLEAGA DK T L+YA Sbjct: 597 ALMVAVGRGHLGTVKLLLEAGADPTKRDKKGRTALYYA 634 Score = 30.4 bits (67), Expect = 5.2 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Frame = -3 Query: 423 CGYGELKCAEILLEAGAAVDALDK-NKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDG 247 CG+ ++ I L G V+ + NK + L A G G V LLL+ GA ++ G Sbjct: 570 CGHEDI--TSIFLAFGFPVNQTSRDNKTSALMVAVGRGHLGTVKLLLEAGADPTKRDKKG 627 Query: 246 KTPIEVAKLN----SQDEVVKLLEQDV 178 +T + AK + + E ++L+E + Sbjct: 628 RTALYYAKNSIMGITNSEEIQLIENAI 654
>V034_FOWPV (Q9J5G9) Putative ankyrin repeat protein FPV034| Length = 415 Score = 50.4 bits (119), Expect = 5e-06 Identities = 28/84 (33%), Positives = 44/84 (52%) Frame = -3 Query: 447 GRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAV 268 GR +LH A + A +L+ GA VD+ D NTP+ AA + LLL +GA + Sbjct: 238 GRTSLHLAIKERNYEAAFVLINNGANVDSFDDVGNTPIFIAASLQDVRFMKLLLDNGADI 297 Query: 267 MLQNLDGKTPIEVAKLNSQDEVVK 196 ++N+ G+TP+ + EV + Sbjct: 298 NVRNVFGETPVNMVITGGSKEVTQ 321 Score = 40.8 bits (94), Expect = 0.004 Identities = 35/135 (25%), Positives = 65/135 (48%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 +D N + D G L +A ++ A+ILL+AG+ ++ KN LH A + K Sbjct: 64 IDKNFNINIADSVGYTLLRYAVEVDDVNIAKILLDAGSIIN---KNDYRLLHSAITHENK 120 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLIDPKTL 127 + ++LL HG + +++ G T + N+ ++V FL K +D +++ ++ Sbjct: 121 KMIELLCLHGININVKDDKGYTALYYTICNNNYDMV------CFLLEKNADISIVNKYSM 174 Query: 126 PCFWSLSGAMSWHGV 82 F LS + +H V Sbjct: 175 LHF--LSTSNKYHNV 187
>NOTC3_MOUSE (Q61982) Neurogenic locus notch homolog protein 3 precursor (Notch 3)| [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain] Length = 2318 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/97 (32%), Positives = 49/97 (50%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D G+ ALH+A ++ LL+ GA D D + TPL AA G E Sbjct: 1931 ADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAK 1990 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LLL H A + + + P +VA+ ++V+LL+Q Sbjct: 1991 LLLDHLANREITDHLDRLPRDVAQERLHQDIVRLLDQ 2027 Score = 45.8 bits (107), Expect = 1e-04 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Frame = -3 Query: 528 NTASVGDAEGLKKAL--DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +TA DA+G+ + L + + D +G AL A E L+ + A V+A+D Sbjct: 1878 HTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1937 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + LH+AA E LLK+GA +Q+ +TP+ +A E KLL Sbjct: 1938 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLL 1992 Score = 40.0 bits (92), Expect = 0.007 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 D G ALH A Y A+ LL+AGA +A D + TPLH A + +L+++ Sbjct: 1837 DRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNR 1896 Query: 276 AAVM-LQNLDGKTPIEVA 226 + + + DG T + +A Sbjct: 1897 STDLDARMADGSTALILA 1914 Score = 35.0 bits (79), Expect = 0.21 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Frame = -3 Query: 390 LLEAGAAVDA-LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNS 214 L+ GA + A D+ T LH AA Y R + LL GA Q+ G+TP+ A Sbjct: 1825 LICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTAD 1884 Query: 213 QDEVVKLL 190 V ++L Sbjct: 1885 AQGVFQIL 1892
>NOTC2_MOUSE (O35516) Neurogenic locus notch homolog protein 2 precursor (Notch 2)| (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain] Length = 2470 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/97 (30%), Positives = 50/97 (51%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D G+ ALH+A ++ +LL+ GA D D + TPL AA G E Sbjct: 1966 ADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAK 2025 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 +LL H A + + + P +VA+ ++V+LL++ Sbjct: 2026 ILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDE 2062 Score = 43.5 bits (101), Expect = 6e-04 Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 34/149 (22%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--------- 382 +H A A+ K+ LD GA+++ +D GR LH A +IL+ Sbjct: 1879 LHLAARYSRADAAKRLLDAGADRNAQDNMGRCPLHAAVAGDAQGVFQILIRNRVTDLDAR 1938 Query: 381 -------------------------AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 A V+A+D + + LH+AA E LLLK+G Sbjct: 1939 MNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNG 1998 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A +Q+ +TP+ +A E K+L Sbjct: 1999 ANRDMQDNKEETPLFLAAREGSYEAAKIL 2027 Score = 40.4 bits (93), Expect = 0.005 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 2/99 (2%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + + + D G ALH A Y A+ LL+AGA +A D PLH A + Sbjct: 1864 GASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADRNAQDNMGRCPLHAAVAGDAQGV 1923 Query: 300 VDLLLKHGAAVMLQNL-DGKTP-IEVAKLNSQDEVVKLL 190 +L+++ + + DG TP I A+L + V +L+ Sbjct: 1924 FQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELI 1962 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/84 (30%), Positives = 36/84 (42%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A+V + E L GAN+D +D + L A G + A+ILL+ A D Sbjct: 1977 SALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDI 2036 Query: 360 LDKNKNTPLHYAAGYGRKECVDLL 289 D P A + V LL Sbjct: 2037 TDHMDRLPRDVARDRMHHDIVRLL 2060
>EHMT2_MOUSE (Q9Z148) Histone-lysine N-methyltransferase, H3 lysine-9 specific 3| (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a) Length = 1263 Score = 50.1 bits (118), Expect = 6e-06 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 1/116 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H A G E L GAN + D + R L A L+ A +++ G V + + Sbjct: 742 LHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQLGGCVYSKE 801 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ +T LH+AA G E V LLL G V Q+ G TPI A + +V+++L Sbjct: 802 EDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRML 857 Score = 49.3 bits (116), Expect = 1e-05 Identities = 31/86 (36%), Positives = 44/86 (51%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 ++ L GA+ D E LH+A G AE+LL A + A++ + +TPLH AA Sbjct: 854 IRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNAQCDLHAVNYHGDTPLHIAAR 913 Query: 318 YGRKECVDLLLKHGAAVMLQNLDGKT 241 +CV L L GA L+N +G T Sbjct: 914 ESYHDCVLLFLSRGANPELRNKEGDT 939 Score = 46.2 bits (108), Expect = 9e-05 Identities = 29/94 (30%), Positives = 44/94 (46%) Frame = -3 Query: 471 NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDL 292 N + R LH A G ++ +LL+AGA ++A+DK + TPL A E Sbjct: 730 NFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARY 789 Query: 291 LLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +++ G V + DG T + A E+V LL Sbjct: 790 MVQLGGCVYSKEEDGSTCLHHAAKIGNLEMVSLL 823 Score = 43.9 bits (102), Expect = 5e-04 Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 1/115 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGG-ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 +H+ A +G+ E + L G + + +D G + +A + + +LL GA V Sbjct: 808 LHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIDVIRMLLTRGADVTLT 867 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKL 193 D +N LH+A+ G ++LL + N G TP+ +A S + V L Sbjct: 868 DNEENICLHWASFTGSAAIAEVLLNAQCDLHAVNYHGDTPLHIAARESYHDCVLL 922 Score = 39.7 bits (91), Expect = 0.009 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Frame = -3 Query: 441 RALHFACGYGELKCAEILLEAGAAVDALDKN-------KNTPLHYAAGYGRKECVDLLLK 283 R L+ + GEL+ ++L +D LD N K TPLH AA G E +LL+ Sbjct: 705 RQLYLSVKQGELQKVILML-----LDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQ 759 Query: 282 HGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 GA + + +TP+ A +N+ EV + + Q Sbjct: 760 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQ 792
>NOTC2_RAT (Q9QW30) Neurogenic locus notch homolog protein 2 precursor (Notch 2)| [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain] Length = 2471 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/97 (30%), Positives = 50/97 (51%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D G+ ALH+A ++ +LL+ GA D D + TPL AA G E Sbjct: 1968 ADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAK 2027 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 +LL H A + + + P +VA+ ++V+LL++ Sbjct: 2028 ILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDE 2064 Score = 42.7 bits (99), Expect = 0.001 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 34/149 (22%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--------- 382 +H A A+ K+ LD GA+ + +D GR LH A +IL+ Sbjct: 1881 LHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDAR 1940 Query: 381 -------------------------AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 A V+A+D + + LH+AA E LLLK+G Sbjct: 1941 MNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNG 2000 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A +Q+ +TP+ +A E K+L Sbjct: 2001 ANRDMQDNKEETPLFLAAREGSYEAAKIL 2029 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 2/99 (2%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + + + D G ALH A Y A+ LL+AGA +A D PLH A + Sbjct: 1866 GASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGV 1925 Query: 300 VDLLLKHGAAVMLQNL-DGKTP-IEVAKLNSQDEVVKLL 190 +L+++ + + DG TP I A+L + V +L+ Sbjct: 1926 FQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELI 1964 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/84 (30%), Positives = 36/84 (42%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A+V + E L GAN+D +D + L A G + A+ILL+ A D Sbjct: 1979 SALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDI 2038 Query: 360 LDKNKNTPLHYAAGYGRKECVDLL 289 D P A + V LL Sbjct: 2039 TDHMDRLPRDVARDRMHHDIVRLL 2062
>NOTC2_HUMAN (Q04721) Neurogenic locus notch homolog protein 2 precursor (Notch 2)| (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain] Length = 2471 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/97 (30%), Positives = 50/97 (51%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D G+ ALH+A ++ +LL+ GA D D + TPL AA G E Sbjct: 1968 ADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAK 2027 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 +LL H A + + + P +VA+ ++V+LL++ Sbjct: 2028 ILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLDE 2064 Score = 42.7 bits (99), Expect = 0.001 Identities = 38/149 (25%), Positives = 58/149 (38%), Gaps = 34/149 (22%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLE--------- 382 +H A A+ K+ LD GA+ + +D GR LH A +IL+ Sbjct: 1881 LHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDAR 1940 Query: 381 -------------------------AGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 A V+A+D + + LH+AA E LLLK+G Sbjct: 1941 MNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNG 2000 Query: 276 AAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 A +Q+ +TP+ +A E K+L Sbjct: 2001 ANRDMQDNKEETPLFLAAREGSYEAAKIL 2029 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 2/99 (2%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + + + D G ALH A Y A+ LL+AGA +A D PLH A + Sbjct: 1866 GASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGV 1925 Query: 300 VDLLLKHGAAVMLQNL-DGKTP-IEVAKLNSQDEVVKLL 190 +L+++ + + DG TP I A+L + V +L+ Sbjct: 1926 FQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELI 1964 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/84 (30%), Positives = 36/84 (42%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A+V + E L GAN+D +D + L A G + A+ILL+ A D Sbjct: 1979 SALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDI 2038 Query: 360 LDKNKNTPLHYAAGYGRKECVDLL 289 D P A + V LL Sbjct: 2039 TDHMDRLPRDVARDRMHHDIVRLL 2062
>ASZ1_CARPS (Q2QLC6) Ankyrin repeat, SAM and basic leucine zipper| domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) Length = 475 Score = 50.1 bits (118), Expect = 6e-06 Identities = 42/118 (35%), Positives = 61/118 (51%), Gaps = 6/118 (5%) Frame = -3 Query: 522 ASVGDAEGLKKALDGGANKDEEDVEGRRALHFAC---GYGE--LKCAEILLEAGAAVDAL 358 ASV + E ++ LD GAN + D + + L C G E +KC E+LL A + Sbjct: 87 ASVSNVELVRVLLDRGANANF-DKDKQTILITTCSSRGSEEQIVKCVELLLSRNADPNVP 145 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIE-VAKLNSQDEVVKLLE 187 + TP+ YAA G + V LL+ HGA V Q+ G T + A+ ++ V+KLLE Sbjct: 146 CRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDESGYTALTWAARQGHKNVVLKLLE 203 Score = 46.6 bits (109), Expect = 7e-05 Identities = 30/80 (37%), Positives = 41/80 (51%) Frame = -3 Query: 429 FACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLD 250 +A G + +L+ GA V+ D++ T L +AA G K V LL+ GA MLQ D Sbjct: 155 YAARDGHPQVVALLVAHGAEVNTQDESGYTALTWAARQGHKNVVLKLLELGADKMLQTKD 214 Query: 249 GKTPIEVAKLNSQDEVVKLL 190 G P E+AK E+ LL Sbjct: 215 GNIPSEIAKRYKHLEIFSLL 234 Score = 36.6 bits (83), Expect = 0.072 Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 2/124 (1%) Frame = -3 Query: 516 VGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 +G + + L G +E++ ++AL G++ + LL +G +VD+ + TP Sbjct: 27 IGYLDRASQKLKGVLPTEEKNETFKKALTT----GDISLVQELLNSGISVDSSFRYGWTP 82 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI--EVAKLNSQDEVVKLLEQDVFL*SK 163 L YAA E V +LL GA D +T + + S++++VK +E L S+ Sbjct: 83 LMYAASVSNVELVRVLLDRGANANFDK-DKQTILITTCSSRGSEEQIVKCVE---LLLSR 138 Query: 162 PSDP 151 +DP Sbjct: 139 NADP 142 Score = 30.8 bits (68), Expect = 4.0 Identities = 29/99 (29%), Positives = 40/99 (40%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA + +D G AL +A G LLE GA K+ N P A Y E Sbjct: 172 GAEVNTQDESGYTALTWAARQGHKNVVLKLLELGADKMLQTKDGNIPSEIAKRYKHLEIF 231 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 LL ++ L L GK + + ++ + KLL D Sbjct: 232 SLL-----SLSLNPLKGK----LQQQTKEETICKLLATD 261
>POT15_HUMAN (Q6S5H4) Prostate, ovary, testis expressed protein on chromosome 15| Length = 581 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/92 (32%), Positives = 45/92 (48%) Frame = -3 Query: 465 DEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLL 286 ++ D + R ALH A G + ++LL+ ++ LD K T L A ECV +LL Sbjct: 167 NKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLL 226 Query: 285 KHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +HGA +Q+ G T + A N + K L Sbjct: 227 EHGADGNIQDEYGNTALHYAIYNEDKLMAKAL 258 Score = 48.9 bits (115), Expect = 1e-05 Identities = 37/115 (32%), Positives = 57/115 (49%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H ++ G++E ++ LD + D + R AL A E +C +LLE GA + D Sbjct: 177 LHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQD 236 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + NT LHYA K LL +GA + +N G TP+ + + +VVK L Sbjct: 237 EYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFL 291 Score = 39.3 bits (90), Expect = 0.011 Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L+ GA+ + +D G ALH+A + A+ LL GA +++ +K TPL ++ Sbjct: 226 LEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQ 285 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVK-LLEQDV 178 + V L+K A + + G+T + +A +V LLEQ+V Sbjct: 286 QVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNV 329
>NUC2_NEUCR (Q01317) Ankyrin repeat protein nuc-2| Length = 1066 Score = 50.1 bits (118), Expect = 6e-06 Identities = 41/152 (26%), Positives = 63/152 (41%), Gaps = 35/152 (23%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGEL----------------- 406 +H A G++ L+ L G + + D GR LH+A +G L Sbjct: 308 LHQAAIYGNSFVLEYGLSKGVDAERTDAYGRVPLHYASMHGRLDMIDALLNASPKTINLI 367 Query: 405 -----------------KCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHG 277 +C LLE A +D + + PL+ A +G V+LLLKHG Sbjct: 368 DHDNFTPLVHSIVRNHLECVGRLLERSARIDPVSDTDHVPLNLACQHGSVAIVELLLKHG 427 Query: 276 AAVMLQNLDGKTPIE-VAKLNSQDEVVKLLEQ 184 A + L + +G P VA+ E++ LL+Q Sbjct: 428 AKI-LADAEGLYPQHLVARSGQTPEILVLLKQ 458 Score = 46.6 bits (109), Expect = 7e-05 Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 4/114 (3%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDE--EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNT 340 G E LK LD G + +D+ R LH A YG E L G + D Sbjct: 280 GSLEALKVLLDTGLVDIQSWDDINERNCLHQAAIYGNSFVLEYGLSKGVDAERTDAYGRV 339 Query: 339 PLHYAAGYGRKECVDLLLKHG-AAVMLQNLDGKTPIEVAKLNSQDEVV-KLLEQ 184 PLHYA+ +GR + +D LL + L + D TP+ + + + E V +LLE+ Sbjct: 340 PLHYASMHGRLDMIDALLNASPKTINLIDHDNFTPLVHSIVRNHLECVGRLLER 393 Score = 39.3 bits (90), Expect = 0.011 Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Frame = -3 Query: 477 GANKDEED-VEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 GA+ D+ D + G L A G + C + LLE GA + LD+ ++YAA G EC Sbjct: 460 GADLDQIDKLYGWTPLVHAASEGNVPCLQALLETGADPNILDEKDLPAMYYAAWEGHLEC 519 Query: 300 VDLL 289 + LL Sbjct: 520 MKLL 523
>AKR1_ASPOR (Q7Z8U2) Palmitoyltransferase akr1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein akr1) Length = 737 Score = 50.1 bits (118), Expect = 6e-06 Identities = 35/105 (33%), Positives = 50/105 (47%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +I+H G+A L L D D +G L +A G ++ L GA +A Sbjct: 166 NILHLATIDGNAFLLVLLLHQEIPVDVVDQQGHTGLMWAAYKGYPALVDLFLRWGAHANA 225 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 +D+ TPLH+A G CV L+++GA + DGKTP VA Sbjct: 226 VDEGGLTPLHWALVKGSLPCVLKLIEYGADKFAKTRDGKTPAVVA 270 Score = 43.1 bits (100), Expect = 8e-04 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L GA+ DV+G LH A G +LL VD +D+ +T L +AA G Sbjct: 151 LQRGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQEIPVDVVDQQGHTGLMWAAYKGYP 210 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKL-NSQDEVVKLLE 187 VDL L+ GA + G TP+ A + S V+KL+E Sbjct: 211 ALVDLFLRWGAHANAVDEGGLTPLHWALVKGSLPCVLKLIE 251
>TIP1_ARATH (Q52T38) Palmitoyltransferase TIP1 (EC 2.3.1.-) (Ankyrin| repeat-containing S-palmitoyltransferase) (Protein TIP GROWTH DEFECTIVE1) Length = 620 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/104 (31%), Positives = 53/104 (50%), Gaps = 1/104 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALD-GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 V+ A+ GD E L + ++ G++ E D G AL ++ + A+ L+E G V+A Sbjct: 35 VYTAAAYGDLEKLHRLVECEGSSVSEPDALGYYALQWSALNNRVAVAQYLIEHGGDVNAT 94 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 D T LH++A G + +LLL+ GA V ++ G VA Sbjct: 95 DHTGQTALHWSAVRGAIQVAELLLQEGARVDATDMYGYQATHVA 138 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 1/100 (1%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 ++ G + + D G+ ALH++ G ++ AE+LL+ GA VDA D H AA YG+ Sbjct: 85 IEHGGDVNATDHTGQTALHWSAVRGAIQVAELLLQEGARVDATDMYGYQATHVAAQYGQT 144 Query: 306 ECV-DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + ++ K A + + DG++P+ A + ++LL Sbjct: 145 AFLCHVVSKWNADPDVPDNDGRSPLHWAAYKGFADSIRLL 184 Score = 46.2 bits (108), Expect = 9e-05 Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 1/118 (0%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELK-CAEILLEAGAAVDAL 358 +H +A G + + L GA D D+ G +A H A YG+ ++ + A D Sbjct: 102 LHWSAVRGAIQVAELLLQEGARVDATDMYGYQATHVAAQYGQTAFLCHVVSKWNADPDVP 161 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 D + +PLH+AA G + + LLL A Q+ +G TP+ A + E +L Q Sbjct: 162 DNDGRSPLHWAAYKGFADSIRLLLFLDAYRGRQDKEGCTPLHWAAIRGNLEACTVLVQ 219 Score = 42.7 bits (99), Expect = 0.001 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 S +H A G A+ ++ L A + +D EG LH+A G L+ +L++AG D Sbjct: 167 SPLHWAAYKGFADSIRLLLFLDAYRGRQDKEGCTPLHWAAIRGNLEACTVLVQAGKKEDL 226 Query: 360 L--DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPI 235 + DK TP AA ++ V L + +++ + DG +P+ Sbjct: 227 MITDKTGLTPAQLAAEKNHRQ-VSFFLGNARSLLEKRCDGSSPL 269 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ D D +GR LH+A G +LL A DK TPLH+AA G E Sbjct: 156 ADPDVPDNDGRSPLHWAAYKGFADSIRLLLFLDAYRGRQDKEGCTPLHWAAIRGNLEACT 215 Query: 294 LLLKHGAA--VMLQNLDGKTPIEVAKLNSQDEV 202 +L++ G +M+ + G TP ++A + +V Sbjct: 216 VLVQAGKKEDLMITDKTGLTPAQLAAEKNHRQV 248 Score = 31.6 bits (70), Expect = 2.3 Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 1/99 (1%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEA-GAAVDALDKNKNTPLHYAAGYGRKECV 298 ++K E+ + ++ A YG+L+ L+E G++V D L ++A R Sbjct: 22 SSKGIEEESLKNDVYTAAAYGDLEKLHRLVECEGSSVSEPDALGYYALQWSALNNRVAVA 81 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQD 181 L++HG V + G+T + + + +V +LL Q+ Sbjct: 82 QYLIEHGGDVNATDHTGQTALHWSAVRGAIQVAELLLQE 120
>AKR1_EMENI (Q5B0V6) Palmitoyltransferase akr1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein akr1) Length = 737 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/106 (33%), Positives = 49/106 (46%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDA 361 +I+H G+A L L D D +G L +A G C ++ L GA +A Sbjct: 167 NILHLATIDGNAFLLVLLLHQEIPVDVVDQQGHTGLMWAAYKGYPACVDLFLRWGANPNA 226 Query: 360 LDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK 223 +D PLH+A G CV +L++GA DGKTP VA+ Sbjct: 227 VDDGGLAPLHWALVKGSLPCVLKILEYGADRFATTTDGKTPALVAQ 272 Score = 43.5 bits (101), Expect = 6e-04 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L GA+ DV+G LH A G +LL VD +D+ +T L +AA G Sbjct: 152 LQYGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQEIPVDVVDQQGHTGLMWAAYKGYP 211 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKL-NSQDEVVKLLE 187 CVDL L+ GA + G P+ A + S V+K+LE Sbjct: 212 ACVDLFLRWGANPNAVDDGGLAPLHWALVKGSLPCVLKILE 252 Score = 38.5 bits (88), Expect = 0.019 Identities = 32/122 (26%), Positives = 60/122 (49%), Gaps = 3/122 (2%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGA-NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 + A +G+ ++K D + D EG LH+A + + L+++GA V+A Sbjct: 68 IMQVARIGEVSVMQKLFDEKKFTANYSDEEGITPLHWAAINNQYAMCKFLIDSGADVNAK 127 Query: 357 D-KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQD-EVVKLLEQ 184 ++ TP +AA V LLL++GA +L ++ G + +A ++ +V LL Q Sbjct: 128 GGESVATPAMWAAQRCHYYIVHLLLQYGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQ 187 Query: 183 DV 178 ++ Sbjct: 188 EI 189
>AKT2_ARATH (Q38898) Potassium channel AKT2/3| Length = 802 Score = 49.7 bits (117), Expect = 8e-06 Identities = 30/101 (29%), Positives = 49/101 (48%) Frame = -3 Query: 492 KALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYG 313 KA G N D L G + LL+A + D D TPLH AA G Sbjct: 526 KAQQNGENTDVVPPNIASNLIAVVTTGNAALLDELLKAKLSPDITDSKGKTPLHVAASRG 585 Query: 312 RKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++CV +LLKHG + +++++G + + A ++ E+ ++L Sbjct: 586 YEDCVLVLLKHGCNIHIRDVNGNSALWEAIISKHYEIFRIL 626
>NOTC1_BRARE (P46530) Neurogenic locus notch homolog protein 1 precursor| Length = 2437 Score = 49.7 bits (117), Expect = 8e-06 Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Frame = -3 Query: 474 ANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVD 295 A+ + D G+ ALH+A + A +LL+ GA D + + TPL AA G E Sbjct: 2007 ADPNAVDDSGKSALHWAAAVNNVDAAVVLLKNGANKDLQNNKEETPLFLAAREGSYETAK 2066 Query: 294 LLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SK--PSDPVLIDPKT 130 +LL H A + + + P ++A ++V+LLE+ + S P P L P T Sbjct: 2067 VLLDHLANRDIADHLDQLPRDIAHERMHHDIVRLLEEYNLVRSPPLPLSPPLCCPNT 2123 Score = 40.4 bits (93), Expect = 0.005 Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Frame = -3 Query: 477 GAN-KDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 GAN ++ D G ALH A Y A+ LLE+ A + D TPLH A + Sbjct: 1905 GANLHNQTDRTGETALHLAARYARSDAAKRLLESCADANVQDNMGRTPLHAAVAADAQGV 1964 Query: 300 VDLLLKHGAAVMLQNL-DGKTPIEVA 226 +L+++ A + + DG TP+ +A Sbjct: 1965 FQILIRNRATDLDARMHDGTTPLILA 1990 Score = 40.0 bits (92), Expect = 0.007 Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 2/115 (1%) Frame = -3 Query: 528 NTASVGDAEGLKKAL--DGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 + A DA+G+ + L + + D +G L A E L+ A +A+D Sbjct: 1954 HAAVAADAQGVFQILIRNRATDLDARMHDGTTPLILATRLAVEGMVEELINCHADPNAVD 2013 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 + + LH+AA + +LLK+GA LQN +TP+ +A E K+L Sbjct: 2014 DSGKSALHWAAAVNNVDAAVVLLKNGANKDLQNNKEETPLFLAAREGSYETAKVL 2068 Score = 32.3 bits (72), Expect = 1.4 Identities = 18/56 (32%), Positives = 27/56 (48%) Frame = -3 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D+ T LH AA Y R + LL+ A +Q+ G+TP+ A V ++L Sbjct: 1913 DRTGETALHLAARYARSDAAKRLLESCADANVQDNMGRTPLHAAVAADAQGVFQIL 1968
>BCL3_MOUSE (Q9Z2F6) B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3)| Length = 440 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD-KNKNTPLHYAA 322 L A G + + + EG ALH A G + +LLE GA +DA+D K+ +PL +A Sbjct: 212 LDSATSGSVDLEVRNYEGLTALHVAVNTGCQEAVLLLLERGADIDAVDIKSGRSPLIHAV 271 Query: 321 GYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 V LLL HGA V Q G + + A Sbjct: 272 ENNSLNMVQLLLLHGANVNAQMYSGSSALHSA 303 Score = 43.5 bits (101), Expect = 6e-04 Identities = 33/101 (32%), Positives = 53/101 (52%), Gaps = 5/101 (4%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEA--GAAVDALDKNKN--TPLHYAAGYGR 310 GA+ D G+ A+H AC + C + LL++ +VD +N T LH A G Sbjct: 182 GASPMALDRHGQTAIHLACEHRSPSCLQALLDSATSGSVDLEVRNYEGLTALHVAVNTGC 241 Query: 309 KECVDLLLKHGAAVMLQNL-DGKTPIEVAKLNSQDEVVKLL 190 +E V LLL+ GA + ++ G++P+ A N+ +V+LL Sbjct: 242 QEAVLLLLERGADIDAVDIKSGRSPLIHAVENNSLNMVQLL 282 Score = 35.4 bits (80), Expect = 0.16 Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 5/75 (6%) Frame = -3 Query: 393 ILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAA----VMLQNLDGKTPIEVA 226 +L+ AGA+ ALD++ T +H A + C+ LL + + ++N +G T + VA Sbjct: 177 LLVTAGASPMALDRHGQTAIHLACEHRSPSCLQALLDSATSGSVDLEVRNYEGLTALHVA 236 Query: 225 -KLNSQDEVVKLLEQ 184 Q+ V+ LLE+ Sbjct: 237 VNTGCQEAVLLLLER 251 Score = 34.3 bits (77), Expect = 0.36 Identities = 33/120 (27%), Positives = 46/120 (38%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GAN + + G ALH A G G L L+ +GA + + +TPL A + + Sbjct: 286 GANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSGLKNCHNDTPLMVARS---RRVI 342 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQDVFL*SKPSDPVLIDPKTLPCF 118 D+L G A + P + E L + S S P L PK P F Sbjct: 343 DIL--RGKASRAASGSQPEPSPDQSATNSPESSSRLSSNGLQSSPSSSPSLSPPKDAPGF 400 Score = 29.6 bits (65), Expect = 8.8 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Frame = -3 Query: 456 DVEGRRALHFACGYGELKCAEILLE----AGAAVDALDKNKNTPLHYAAGYGRKECVDLL 289 D +G LH A + +L VD + + TPLH A + V LL Sbjct: 119 DEDGDTPLHIAVVQNNIAAVYRILSLFKLGSREVDVHNNLRQTPLHLAVITTLPDMVRLL 178 Query: 288 LKHGAAVMLQNLDGKTPIEVA 226 + GA+ M + G+T I +A Sbjct: 179 VTAGASPMALDRHGQTAIHLA 199
>V240_FOWPV (P14360) Putative ankyrin repeat protein FPV240 (BamHI-ORF7)| Length = 410 Score = 49.7 bits (117), Expect = 8e-06 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 3/120 (2%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDV---EGRRALHFACGYGELKCAEILLEAGAA 370 S +H GD +++ LD G K DV +G LH A L +L+ GA Sbjct: 69 SELHEAVEEGDVVKVEELLDSG--KFINDVIYKKGNTPLHLATISKNLDMMRLLIARGAD 126 Query: 369 VDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 D + ++ TPLH A + ++LLL H A +++ G TP+ +A EV ++L Sbjct: 127 TDVPNTDRFTPLHLAVMSKDIKGIELLLDHRACTNIEDCYGCTPLIIAMSKGDTEVCRML 186 Score = 30.8 bits (68), Expect = 4.0 Identities = 22/70 (31%), Positives = 32/70 (45%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ D + + LH A ++K E+LL+ A + D TPL A G E Sbjct: 124 GADTDVPNTDRFTPLHLAVMSKDIKGIELLLDHRACTNIEDCYGCTPLIIAMSKGDTEVC 183 Query: 297 DLLLKHGAAV 268 +LL GA + Sbjct: 184 RMLLDSGANI 193
>V026_FOWPV (Q9J5H5) Putative ankyrin repeat protein FPV026| Length = 436 Score = 49.7 bits (117), Expect = 8e-06 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 6/111 (5%) Frame = -3 Query: 498 LKKALDGGANKDE-----EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKN-KNTP 337 +K L+ G N +E E++ LHFA G ILL AGA V+ +NTP Sbjct: 80 IKILLEYGVNVNENEYYEEELTCYSVLHFAVDIGNKDIVSILLYAGADVNNTRCYLRNTP 139 Query: 336 LHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 LH A + LLL GA + N +G PI++A + +++V +L Q Sbjct: 140 LHLAIQQKNTDIAKLLLDSGADQNITNENGNIPIQIAVTYNDEKMVNILLQ 190 Score = 48.1 bits (113), Expect = 2e-05 Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = -3 Query: 540 SIVHNTASVGDAEGLKKALDGGANKDEEDVEGRRA-LHFACGYGELKCAEILLEAGAAVD 364 S++H +G+ + + L GA+ + R LH A A++LL++GA + Sbjct: 104 SVLHFAVDIGNKDIVSILLYAGADVNNTRCYLRNTPLHLAIQQKNTDIAKLLLDSGADQN 163 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++N N P+ A Y ++ V++LL++ + + + +G+T + A L+ +V LL Sbjct: 164 ITNENGNIPIQIAVTYNDEKMVNILLQYSPNLEIADYNGRTVLHNAVLDKNINIVSLL 221 Score = 43.1 bits (100), Expect = 8e-04 Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 1/103 (0%) Frame = -3 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 K LD GA+++ + G + A Y + K ILL+ ++ D N T LH A Sbjct: 153 KLLLDSGADQNITNENGNIPIQIAVTYNDEKMVNILLQYSPNLEIADYNGRTVLHNAVLD 212 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDE-VVKLL 190 V LLL++GA V + ++G T I ++ +N D ++K+L Sbjct: 213 KNINIVSLLLENGALVDSKCIEGYT-ILLSSVNRTDPFIIKML 254
>V222_FOWPV (Q9J513) Putative ankyrin repeat protein FPV222| Length = 747 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + + +GR LH AC Y + + L+E+G + +D TPL+YA Y R++ V Sbjct: 388 GASFNLTNRKGRTPLHTACKYNNTEAVKYLIESGCDTNIVDVMSFTPLNYAVYYEREDTV 447 Query: 297 DLLLKHGAA-VMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +LL+ G L + +PI A + ++K+L Sbjct: 448 KILLESGCVDPNLCDYKEVSPIIQAIKRNNKNIIKML 484 Score = 48.5 bits (114), Expect = 2e-05 Identities = 37/112 (33%), Positives = 50/112 (44%), Gaps = 4/112 (3%) Frame = -3 Query: 513 GDAEGLKKALDGGANKDE-EDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTP 337 G E L+ L+ G N D E A+H+A + IL+ A D D+ +NTP Sbjct: 306 GSKELLEILLEYGCNPDICEKTTSTYAMHYAVIRKHYEMLNILIRYDAYTDVKDRQQNTP 365 Query: 336 LHYAAGYGRKEC---VDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 HYA E + LL GA+ L N G+TP+ A + E VK L Sbjct: 366 AHYAVKLPISESCKYLKLLKLAGASFNLTNRKGRTPLHTACKYNNTEAVKYL 417 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/102 (29%), Positives = 48/102 (47%) Frame = -3 Query: 495 KKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGY 316 K + GA + +++ LH A G K E+LL GA +AL T LHY+ Sbjct: 121 KMLIQNGALVNMNNMKNITPLHIASSSGSYKMVELLLLHGANTNALTSYGETSLHYSVSS 180 Query: 315 GRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +LL+++G V + N D T + +A ++V+LL Sbjct: 181 NDLNISELLIENGTNVNVANKDSITALIIAVEIMSIDLVRLL 222 Score = 40.4 bits (93), Expect = 0.005 Identities = 28/91 (30%), Positives = 44/91 (48%) Frame = -3 Query: 405 KCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVA 226 K ++L AGA+ + ++ TPLH A Y E V L++ G + ++ TP+ A Sbjct: 379 KYLKLLKLAGASFNLTNRKGRTPLHTACKYNNTEAVKYLIESGCDTNIVDVMSFTPLNYA 438 Query: 225 KLNSQDEVVKLLEQDVFL*SKPSDPVLIDPK 133 +++ VK+L L S DP L D K Sbjct: 439 VYYEREDTVKIL-----LESGCVDPNLCDYK 464 Score = 39.7 bits (91), Expect = 0.009 Identities = 30/115 (26%), Positives = 54/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H +S G + ++ L GAN + G +LH++ +L +E+L+E G V+ + Sbjct: 141 LHIASSSGSYKMVELLLLHGANTNALTSYGETSLHYSVSSNDLNISELLIENGTNVNVAN 200 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 K+ T L A + V LLL GA L+ + + V + + ++K L Sbjct: 201 KDSITALIIAVEIMSIDLVRLLLDKGADTNAIGLE-RFKLYVTETKQNNNILKYL 254 Score = 39.7 bits (91), Expect = 0.009 Identities = 23/73 (31%), Positives = 40/73 (54%) Frame = -3 Query: 408 LKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEV 229 L+ A++L++ GA V+ + TPLH A+ G + V+LLL HGA G+T + Sbjct: 117 LEIAKMLIQNGALVNMNNMKNITPLHIASSSGSYKMVELLLLHGANTNALTSYGETSLHY 176 Query: 228 AKLNSQDEVVKLL 190 + ++ + +LL Sbjct: 177 SVSSNDLNISELL 189 Score = 32.3 bits (72), Expect = 1.4 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 1/87 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL- 358 +H + E +K ++ G + + DV L++A Y +ILLE+G L Sbjct: 402 LHTACKYNNTEAVKYLIESGCDTNIVDVMSFTPLNYAVYYEREDTVKILLESGCVDPNLC 461 Query: 357 DKNKNTPLHYAAGYGRKECVDLLLKHG 277 D + +P+ A K + +LL G Sbjct: 462 DYKEVSPIIQAIKRNNKNIIKMLLNAG 488
>POTE8_HUMAN (Q6S8J7) Prostate, ovary, testis expressed protein on chromosome 8| Length = 498 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/96 (30%), Positives = 42/96 (43%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 G ++ D + R ALH AC G + +LL+ + D K T L A EC Sbjct: 89 GPGINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECA 148 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 +LL+HG L ++ G T + A N + K L Sbjct: 149 LMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTL 184 Score = 46.6 bits (109), Expect = 7e-05 Identities = 36/115 (31%), Positives = 53/115 (46%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALD 355 +H + G++E + LD D + R AL A E +CA +LL+ G + D Sbjct: 103 LHLACANGNSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPD 162 Query: 354 KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 NT LHYA K LL +GA + +N G TP+ +A + +VK L Sbjct: 163 MYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFL 217 Score = 39.3 bits (90), Expect = 0.011 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Frame = -3 Query: 435 LHFACGYGELKCAE-ILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQ 259 LH A +GE+ A+ I++ G ++ DK K T LH A G E V LLL + + Sbjct: 69 LHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANGNSEVVSLLLDRQCQLHVF 128 Query: 258 NLDGKTPIEVAKLNSQDEVVKLLEQ 184 + +T + A +DE +L Q Sbjct: 129 DSKKRTALIKAVQCQEDECALMLLQ 153 Score = 38.9 bits (89), Expect = 0.015 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 3/107 (2%) Frame = -3 Query: 486 LDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRK 307 L G + + D+ G ALH+A + A+ LL GA +++ +K TPL A ++ Sbjct: 152 LQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQ 211 Query: 306 ECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ---DVF 175 V L+K A + + G+T + +A +V LL Q DVF Sbjct: 212 RMVKFLIKKKANLNALDRFGRTALILAVRCGSASIVSLLLQQNIDVF 258 Score = 32.0 bits (71), Expect = 1.8 Identities = 25/96 (26%), Positives = 45/96 (46%) Frame = -3 Query: 477 GANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKECV 298 GA+ + ++ G L A + + + L++ A ++ALD+ T L A G V Sbjct: 188 GADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFGRTALILAVRCGSASIV 247 Query: 297 DLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 LLL+ V Q++ G+T + A + + +LL Sbjct: 248 SLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLL 283
>NOTC1_HUMAN (P46531) Neurogenic locus notch homolog protein 1 precursor (Notch 1)| (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain] Length = 2556 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/105 (28%), Positives = 54/105 (51%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 L+ ++ A+ + D G+ ALH+A + A +LL+ GA D + + TPL AA Sbjct: 2012 LEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAR 2071 Query: 318 YGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 G E +LL H A + + + P ++A+ ++V+LL++ Sbjct: 2072 EGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDE 2116 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + ++ D G ALH A Y A+ LLEA A + D TPLH A + Sbjct: 1918 GASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGV 1977 Query: 300 VDLLLKHGAAVMLQNL-DGKTPIEVA 226 +L+++ A + + DG TP+ +A Sbjct: 1978 FQILIRNRATDLDARMHDGTTPLILA 2003 Score = 33.9 bits (76), Expect = 0.47 Identities = 18/70 (25%), Positives = 33/70 (47%) Frame = -3 Query: 399 AEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKL 220 ++ + + + + D+ T LH AA Y R + LL+ A +Q+ G+TP+ A Sbjct: 1912 SDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVS 1971 Query: 219 NSQDEVVKLL 190 V ++L Sbjct: 1972 ADAQGVFQIL 1981
>NOTC1_RAT (Q07008) Neurogenic locus notch homolog protein 1 precursor (Notch 1)| [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain] Length = 2531 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/105 (28%), Positives = 54/105 (51%) Frame = -3 Query: 498 LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAG 319 L+ ++ A+ + D G+ ALH+A + A +LL+ GA D + + TPL AA Sbjct: 2001 LEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNKEETPLFLAAR 2060 Query: 318 YGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLLEQ 184 G E +LL H A + + + P ++A+ ++V+LL++ Sbjct: 2061 EGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDE 2105 Score = 43.1 bits (100), Expect = 8e-04 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Frame = -3 Query: 480 GGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDALDKNKNTPLHYAAGYGRKEC 301 G + ++ D G ALH A Y A+ LLEA A + D TPLH A + Sbjct: 1907 GASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGV 1966 Query: 300 VDLLLKHGAAVMLQNL-DGKTPIEVA 226 +LL++ A + + DG TP+ +A Sbjct: 1967 FQILLRNRATDLDARMHDGTTPLILA 1992 Score = 33.9 bits (76), Expect = 0.47 Identities = 18/70 (25%), Positives = 33/70 (47%) Frame = -3 Query: 399 AEILLEAGAAVDALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKL 220 ++ + + + + D+ T LH AA Y R + LL+ A +Q+ G+TP+ A Sbjct: 1901 SDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVS 1960 Query: 219 NSQDEVVKLL 190 V ++L Sbjct: 1961 ADAQGVFQIL 1970
>AKR1_GIBZE (Q4I8B6) Palmitoyltransferase AKR1 (EC 2.3.1.-) (Ankyrin| repeat-containing protein AKR1) Length = 702 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/112 (33%), Positives = 53/112 (47%), Gaps = 5/112 (4%) Frame = -3 Query: 531 HNTASVGDAEG----LKKALDGGANKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVD 364 +NT + G L L G D D G AL +A G +C ++ L GA+V Sbjct: 130 YNTLHISTFNGNVLLLVLLLHQGIPVDVIDTFGHTALMWAAYKGFPQCVDLFLRWGASVH 189 Query: 363 ALDKNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAK-LNSQ 211 A D+ T LH+A G C+ L+++GA + GKTP AK LN++ Sbjct: 190 ATDEQGFTALHWALVKGSPGCILKLIEYGADRFAKTQTGKTPSVTAKELNTE 241 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Frame = -3 Query: 534 VHNTASVGDAEGLKKALDGGA-NKDEEDVEGRRALHFACGYGELKCAEILLEAGAAVDAL 358 + A VGD ++K + G + D EG LH+A + + L+E GA ++ Sbjct: 32 IMQVARVGDVPAMEKLFESGEYDATYHDDEGITPLHWAAINNQYAMCKFLIEHGAEINRK 91 Query: 357 D-KNKNTPLHYAAGYGRKECVDLLLKHGAAVMLQNLDGKTPIEVAKLNSQDEVVKLL 190 ++ TPL +AA V+LLL+HGA ++ + G + ++ N ++ LL Sbjct: 92 GGESIATPLQWAAQRCHYYTVNLLLQHGADPLVTDAQGYNTLHISTFNGNVLLLVLL 148 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,856,258 Number of Sequences: 219361 Number of extensions: 1714970 Number of successful extensions: 6782 Number of sequences better than 10.0: 463 Number of HSP's better than 10.0 without gapping: 5000 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6402 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6655306086 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
