ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal7g07 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 102 bits (254), Expect = 1e-21 Identities = 47/115 (40%), Positives = 70/115 (60%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG + +E Q ++ G GT +MAPE++ KPY RK DVYSFGI LWE+ +P+ + Sbjct: 231 FGTSCLETQC-REAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLPFQGM 289 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 + + AV +N RP +P C A A+++++CW NP KRPD +V ++E D Sbjct: 290 TPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDFSNIVAVLEKYD 344
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 89.7 bits (221), Expect = 7e-18 Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 2/119 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG +R N GT +MAPEV+ P + CD YS+G+ LWE+ ++P+ L Sbjct: 152 FGASRFH--NHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGL 209 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL--DTS 329 V+ VV +N R IP CP +FA ++ +CW+ + KRP +++ ++E++ DTS Sbjct: 210 EGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTS 268
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 89.0 bits (219), Expect = 1e-17 Identities = 39/114 (34%), Positives = 64/114 (56%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG +R N GT +MAPEV+ P + CD YS+G+ LWE+ ++P+ L Sbjct: 152 FGASRFH--NHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGL 209 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 V+ VV +N R IP CP +FA ++ +CW+ + KRP +++ ++E++ Sbjct: 210 EGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 88.2 bits (217), Expect = 2e-17 Identities = 38/115 (33%), Positives = 66/115 (57%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG++R++ + MT + G + YMAPEV G + K DVYS+G+ L+E+ D P D+ Sbjct: 1449 FGLSRLKKEQASQMTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDM 1508 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 ++ +++ RP IP S + I+ +CWD NPD RP +++ ++ ++ Sbjct: 1509 KPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEME 1563
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 86.7 bits (213), Expect = 6e-17 Identities = 44/115 (38%), Positives = 65/115 (56%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG+AR E M+ A GT +MAPEV+ +++ DV+SFG+ LWE+ ++PY + Sbjct: 268 FGLAR-EWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGI 325 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 V+ V L IP CP FA +M CW +P +RPD ++Q +EAL+ Sbjct: 326 DCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALE 380
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 86.3 bits (212), Expect = 8e-17 Identities = 41/117 (35%), Positives = 66/117 (56%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG+AR + K A GT +MAPEV+ +++ DV+SFG+ LWE+ ++PY ++ Sbjct: 249 FGLAREWHKTTK--MSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREI 306 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 V+ V L IP CP FA ++ +CWD +P RPD +++ +E ++ S Sbjct: 307 DALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQS 363
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 85.5 bits (210), Expect = 1e-16 Identities = 46/109 (42%), Positives = 64/109 (58%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG AR++ N MT GT + APEV+ G+ Y K DV+SFG+ +WE+ P+ + Sbjct: 1506 FGFARIKEDNTT-MTRC-GTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAEC 1563 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 +F VS ++ + RP IP CP FA +++KCW KRP M EVVQ Sbjct: 1564 NFMKVSLDIL-EGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQ 1611 Score = 58.5 bits (140), Expect = 2e-08 Identities = 34/116 (29%), Positives = 63/116 (54%), Gaps = 8/116 (6%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGAT--GTLGYMAPEVLDGKPYNRK--CDVYSFGICLWEIYCCDMP 512 FG+ +V+++ K T GT+ ++APE+L+ DVYSFGI LWE+ + P Sbjct: 927 FGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQP 986 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSA----FANIMRKCWDGNPDKRPDMDEVV 356 Y ++ A ++ +V+ +RP I +A + +++++CW + RP E++ Sbjct: 987 YKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIM 1042
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 84.0 bits (206), Expect = 4e-16 Identities = 42/118 (35%), Positives = 66/118 (55%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG+AR E N + M+ A GT +M PEV+ Y++ DV+S+G+ LWE+ + PY Sbjct: 291 FGLAR-EMYNTQRMSAA-GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGF 348 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 326 V+ V L IP+ CP + +M+ CW +P KRP E+++ +E++ SK Sbjct: 349 DPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSK 406
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 83.6 bits (205), Expect = 5e-16 Identities = 45/114 (39%), Positives = 63/114 (55%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG++R++A A GT +MAPEVL +P N K DVYSFG+ LWE+ P+ +L Sbjct: 695 FGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNL 754 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 + A V +AV + R +IPR A I+ CW P KRP ++ L+ L Sbjct: 755 NPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 81.6 bits (200), Expect = 2e-15 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 1/102 (0%) Frame = -3 Query: 640 MTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSF-ADVSSAVVHQ 464 MT G+ +MAPEV +G Y+ KCDV+S+GI LWE+ P+ ++ A VH Sbjct: 186 MTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHN 245 Query: 463 NLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 RP + + P ++M +CW +P +RP M+E+V++M L Sbjct: 246 GTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 81.6 bits (200), Expect = 2e-15 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 1/102 (0%) Frame = -3 Query: 640 MTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSF-ADVSSAVVHQ 464 MT G+ +MAPEV +G Y+ KCDV+S+GI LWE+ P+ ++ A VH Sbjct: 186 MTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHN 245 Query: 463 NLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 RP + + P ++M +CW +P +RP M+E+V++M L Sbjct: 246 GTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 80.5 bits (197), Expect = 4e-15 Identities = 35/108 (32%), Positives = 62/108 (57%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ Sbjct: 255 FGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDV 313 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + + V +L +P CP F ++R+CW+ P RP +++ Sbjct: 314 DSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL 361
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 80.5 bits (197), Expect = 4e-15 Identities = 35/108 (32%), Positives = 62/108 (57%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ Sbjct: 288 FGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDV 346 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + + V +L +P CP F ++R+CW+ P RP +++ Sbjct: 347 DSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL 394
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 79.7 bits (195), Expect = 7e-15 Identities = 35/108 (32%), Positives = 62/108 (57%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ Sbjct: 288 FGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDV 346 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + + V +L +P CP F ++R+CW+ P RP +++ Sbjct: 347 DSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFRQIL 394
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 79.3 bits (194), Expect = 1e-14 Identities = 45/117 (38%), Positives = 61/117 (52%), Gaps = 6/117 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPY--- 509 FG+A + N DM G TL YMAPE + Y KCDVYSFGI LWE+ +PY Sbjct: 153 FGLATDMSNNKTDMQG---TLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLPYSHL 209 Query: 508 --PDLSFADVSSAVVHQNLRPDIPRC-CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 P+ +A + + + L + R CP +M C D NP+KRP M E+ + + Sbjct: 210 ENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL 266
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 77.4 bits (189), Expect = 4e-14 Identities = 37/117 (31%), Positives = 61/117 (52%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG+AR + K A GT +MAPEV+ +++ DV+S+G+ LWE+ ++P+ + Sbjct: 295 FGLAREWHRTTK--MSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGI 352 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 V+ V L IP CP FA +M CW+ +P RP ++ + ++ S Sbjct: 353 DGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEES 409
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 77.0 bits (188), Expect = 5e-14 Identities = 37/115 (32%), Positives = 63/115 (54%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG+AR + K T GT +MAPEV+ +++ D++S+G+ LWE+ ++PY + Sbjct: 290 FGLAREWHRTTKMSTA--GTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVPYRGI 347 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 V+ V L IP CP FA +M++CW +P RP +++ + A++ Sbjct: 348 DGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIE 402
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 76.3 bits (186), Expect = 8e-14 Identities = 33/101 (32%), Positives = 52/101 (51%) Frame = -3 Query: 640 MTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQN 461 MT G+ +MAPEV +G Y KCD++S+ I LWE+ P+ + A +++ Sbjct: 170 MTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKG 229 Query: 460 LRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 RP + CP ++M CW P+ RP M +V +M + Sbjct: 230 ERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEI 270
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 75.5 bits (184), Expect = 1e-13 Identities = 34/112 (30%), Positives = 61/112 (54%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++PY D+ Sbjct: 298 FGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDV 356 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + + V +L +P CP F +M++ W P RP + + ++ Sbjct: 357 DSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLD 408
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 75.1 bits (183), Expect = 2e-13 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 1/141 (0%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPD 503 FG+A+ E + K + + + + APE L ++ K DV+SFG+ LWE++ PYP Sbjct: 330 FGLAKAELR--KGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPK 387 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 +S +VS AV + R + P CP +M CW+ P +RP ++V+ + S G Sbjct: 388 MSLKEVSEAV-EKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKLGRELRSVG 446 Query: 322 GGMIPDGQSSGCLCFTRARGP 260 GQ + TR++ P Sbjct: 447 VAAPAGGQEAEGSAPTRSQDP 467
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 74.3 bits (181), Expect = 3e-13 Identities = 33/112 (29%), Positives = 61/112 (54%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FG ++ + M+ A GT+ ++APEV+ +P + K D++SFG+ LWE+ ++PY D+ Sbjct: 298 FGTSKELSDKSTKMSFA-GTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDV 356 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + + V +L +P CP F +M++ W P RP + + ++ Sbjct: 357 DSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLD 408
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 73.6 bits (179), Expect = 5e-13 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 1/141 (0%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPD 503 FG+A+ E K + + + + APE L ++ K DV+SFG+ LWE++ PYP Sbjct: 369 FGLAKAER---KGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPK 425 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 +S +VS AV + R + P CP + +M CW+ P +RP ++V+ + S G Sbjct: 426 MSLKEVSEAV-EKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRELRSVG 484 Query: 322 GGMIPDGQSSGCLCFTRARGP 260 GQ + TR++ P Sbjct: 485 VSAPAGGQEAEGSAPTRSQDP 505
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 73.6 bits (179), Expect = 5e-13 Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 11/143 (7%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEIYCCDMPYP 506 FG +R +++ + +MT G L +MAPEV Y K DV+S+ +CLWE+ ++P+ Sbjct: 605 FGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEIPFA 664 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME------ 344 L A ++ + + ++RP I P ++++ + W+ P+ RP+ EVV+ +E Sbjct: 665 HLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRGWNACPEGRPEFSEVVRKLEECLCNV 724 Query: 343 ---ALDTSKGGGMIPDGQSSGCL 284 + +S G + SS CL Sbjct: 725 ELMSPASSNSSGSLSPSSSSDCL 747
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 73.6 bits (179), Expect = 5e-13 Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 12/152 (7%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEIYCCDMPYP 506 FG +R +++ + +MT G L +MAPEV Y K DV+S+ +CLWEI ++P+ Sbjct: 708 FGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFA 767 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV---------- 356 L A ++ + + ++RP I P ++++ + W+ P+ RP+ EVV Sbjct: 768 HLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNI 827 Query: 355 QLMEALDTSKGGGMIPDGQSSGCLCFTRARGP 260 +LM ++ G + P S C GP Sbjct: 828 ELMSPASSNSSGSLSPSSSSD---CLVNRGGP 856
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 72.4 bits (176), Expect = 1e-12 Identities = 42/143 (29%), Positives = 74/143 (51%), Gaps = 11/143 (7%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEIYCCDMPYP 506 FG +R +++ + +MT G L +MAPEV Y K DV+S+ +CLWE+ ++P+ Sbjct: 606 FGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYSLCLWELLTGEIPFA 665 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME------ 344 L A ++ + + ++RP I P ++++ + W+ P+ RP+ EVV +E Sbjct: 666 HLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVSKLEECLCNV 725 Query: 343 ---ALDTSKGGGMIPDGQSSGCL 284 + +S G + SS CL Sbjct: 726 ELMSPASSNSSGSLSPSSSSDCL 748
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 69.7 bits (169), Expect = 8e-12 Identities = 38/94 (40%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE L + Y + DV+SFGI LWEI+ PYP + ++ S ++ + R + P Sbjct: 653 WMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFS-LLREGHRMERPPN 711 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 CPS +MR+CW P +RP QL+EALD Sbjct: 712 CPSELYGLMRECWHAAPSQRPTFK---QLVEALD 742
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 69.3 bits (168), Expect = 1e-11 Identities = 42/141 (29%), Positives = 67/141 (47%), Gaps = 1/141 (0%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPD 503 FG+A+ E K + + + + APE L + K DV+SFG+ LWE++ PYP Sbjct: 371 FGLAKAER---KGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPK 427 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 +S +VS A V + R + P CP +M CW+ P +RP ++ + + S G Sbjct: 428 MSLKEVSEA-VEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAG 486 Query: 322 GGMIPDGQSSGCLCFTRARGP 260 GQ + R++ P Sbjct: 487 APASVSGQDADGSTSPRSQEP 507
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 69.3 bits (168), Expect = 1e-11 Identities = 38/94 (40%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE L + Y + DV+SFGI LWEI+ PYP + ++ S ++ + R D P Sbjct: 655 WMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFS-LLREGHRMDRPPH 713 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 CP +MR+CW P +RP QL+EALD Sbjct: 714 CPPELYGLMRECWHAAPSQRPTFK---QLVEALD 744
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 3/124 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+AR ++P + + L +MAPE + K Y + DV+SFG+ LWEI+ PY Sbjct: 1056 FGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPY 1115 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 P + + + R P A +IM+ CW G+P RP ++V+++ D Sbjct: 1116 PGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILG--DLL 1173 Query: 328 KGGG 317 +GGG Sbjct: 1174 QGGG 1177
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 3/124 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+AR ++P + + L +MAPE + K Y + DV+SFG+ LWEI+ PY Sbjct: 1056 FGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPY 1115 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 P + + + R P A +IM+ CW G+P RP ++V+++ D Sbjct: 1116 PGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILG--DLL 1173 Query: 328 KGGG 317 +GGG Sbjct: 1174 QGGG 1177
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 68.2 bits (165), Expect = 2e-11 Identities = 43/121 (35%), Positives = 58/121 (47%), Gaps = 3/121 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPY 509 FG+AR G L +MAPE L K Y+ K DV+S+GI LWEI PY Sbjct: 575 FGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPY 634 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 P + A+ + R + P C +MR+CW N D RP E+V+ M+ L + Sbjct: 635 PTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQT 694 Query: 328 K 326 K Sbjct: 695 K 695
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 68.2 bits (165), Expect = 2e-11 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P C Sbjct: 820 WMAPESIFNCVYTFESDVWSYGILLWELFSLGSSPYPGMPVDSKFYKMIKEGYRMFSPEC 879 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P +IM+ CWD +P +RP ++VQL+E Sbjct: 880 SPPEMYDIMKSCWDADPLQRPTFKQIVQLIE 910
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 67.4 bits (163), Expect = 4e-11 Identities = 42/110 (38%), Positives = 60/110 (54%), Gaps = 3/110 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY +PY Sbjct: 333 FGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPY 387 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 P + DV V + + D P CP+ +M+KCW +P RP ++ Sbjct: 388 PRIPLKDVVPR-VEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQL 436
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 67.0 bits (162), Expect = 5e-11 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNL 458 GA + + APE L ++ K DV++FG+ LWEI M PYP + + V ++ ++ Sbjct: 398 GAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE-LLEKDY 456 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 R + P CP +MR CW NP RP E+ Q E + Sbjct: 457 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 496
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 67.0 bits (162), Expect = 5e-11 Identities = 39/122 (31%), Positives = 59/122 (48%), Gaps = 3/122 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PY 509 FG+AR ++P + + L +MAPE + K Y + DV+SFG+ LWEI+ PY Sbjct: 1056 FGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPY 1115 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 P + + + R P A IM CW G+P RP E+V+++ L Sbjct: 1116 PGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGDLLQG 1175 Query: 328 KG 323 +G Sbjct: 1176 RG 1177
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 67.0 bits (162), Expect = 5e-11 Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 17/131 (12%) Frame = -3 Query: 679 FGVARVEAQNPK--DMTGATGTLGYMAPEVL-------------DGK--PYNRKCDVYSF 551 FG+++ + + + + T GT +MAPEV+ DGK Y K DVYSF Sbjct: 1155 FGLSKTKDSSTRYSNQTWNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSF 1214 Query: 550 GICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD 371 G+ +E+ D+P+P+ + +V + +RPD+P CP ++ CW+ +P KRP Sbjct: 1215 GMVCYEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPS 1274 Query: 370 MDEVVQLMEAL 338 + Q ++ L Sbjct: 1275 FAVICQKLKYL 1285
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 67.0 bits (162), Expect = 5e-11 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNL 458 GA + + APE L ++ K DV++FG+ LWEI M PYP + + V ++ ++ Sbjct: 284 GAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE-LLEKDY 342 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 R + P CP +MR CW NP RP E+ Q E + Sbjct: 343 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 382
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 67.0 bits (162), Expect = 5e-11 Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNL 458 GA + + APE L ++ K DV++FG+ LWEI M PYP + + V ++ ++ Sbjct: 398 GAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE-LLEKDY 456 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 R + P CP +MR CW NP RP E+ Q E + Sbjct: 457 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 496
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 66.6 bits (161), Expect = 7e-11 Identities = 28/92 (30%), Positives = 49/92 (53%) Frame = -3 Query: 580 YNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKC 401 Y+ K DVY F + +WEI ++P+ DL + S+ V + LRP IP C ++ +C Sbjct: 287 YSEKVDVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPELKLLLTQC 346 Query: 400 WDGNPDKRPDMDEVVQLMEALDTSKGGGMIPD 305 W+ +P+ RP +V ++ + + G + D Sbjct: 347 WEADPNDRPPFTYIVNKLKEISWNNPIGFVSD 378
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 66.6 bits (161), Expect = 7e-11 Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE L + Y + DV+SF I LWEI+ PYP + ++ S ++ + R + P Sbjct: 652 WMAPEALFDRVYTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFS-LLREGHRMERPPN 710 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 CPS +MR+CW P +RP QL+EALD Sbjct: 711 CPSELYGLMRECWHAAPSQRPTFK---QLVEALD 741
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 66.2 bits (160), Expect = 9e-11 Identities = 40/119 (33%), Positives = 63/119 (52%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1224 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP A +M KCW + RP + E+V + ++ Sbjct: 1284 PYPDVNTFDITIYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSI 1341
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/119 (36%), Positives = 63/119 (52%), Gaps = 3/119 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY +PY Sbjct: 333 FGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPY 387 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 P + DV V + + D P CP A +M+ CW + RP ++ + +E + T Sbjct: 388 PRIPLKDVVPR-VEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKT 445
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 65.9 bits (159), Expect = 1e-10 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P Sbjct: 833 WMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEH 892 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P+ ++M+ CWD +P KRP +VVQL+E Sbjct: 893 APAEMYDVMKTCWDADPLKRPTFKQVVQLIE 923
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1221 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1280 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP A +M KCW + RP E+V + ++ Sbjct: 1281 PYPDVNTFDITIYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSI 1338
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 65.9 bits (159), Expect = 1e-10 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -3 Query: 613 YMAPEVLDGKPYN---RKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIP 443 ++APE L KP + R D++SF + LWE+ ++P+ DLS ++ V + LRP IP Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIP 414 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +M+ C + +P KRP D +V ++E + Sbjct: 415 PGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKM 449
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -3 Query: 613 YMAPEVLDGKPYN---RKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIP 443 ++APE L KP + R D++SF + LWE+ ++P+ DLS ++ V + LRP +P Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTVP 414 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +M+ C + +P KRP D +V ++E + Sbjct: 415 PGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKM 449
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P Sbjct: 273 WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH 332 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 333 APAEMYDIMKTCWDADPLKRPTFKQIVQLIE 363
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P Sbjct: 835 WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH 894 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 895 APAEMYDIMKTCWDADPLKRPTFKQIVQLIE 925
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ +G + + APE + + + DV+SFGI +WE+ + P Sbjct: 758 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERP 817 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +LS +V A+ + R P CPSA +M +CW +RP ++V +++ L Sbjct: 818 YWELSNHEVMKAI-NDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P Sbjct: 836 WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH 895 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 896 APAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P Sbjct: 837 WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH 896 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 897 APAEMYDIMKTCWDADPLKRPTFKQIVQLIE 927
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P Sbjct: 834 WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH 893 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 894 APAEMYDIMKTCWDADPLKRPTFKQIVQLIE 924
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/119 (36%), Positives = 64/119 (53%), Gaps = 3/119 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY +PY Sbjct: 333 FGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPY 387 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 P + DV V + + D P CP A ++M+ CW + RP ++ + +E + T Sbjct: 388 PRIPLKDVVPR-VEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRT 445
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 65.5 bits (158), Expect = 1e-10 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWE++ PYP + ++ + R P Sbjct: 836 WMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEH 895 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 896 APAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1224 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1284 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1224 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1284 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/133 (27%), Positives = 67/133 (50%), Gaps = 4/133 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ + P Sbjct: 777 FGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERP 836 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y D+S DV A+ + R P CP+ +M CW + +RP +++V +++ + Sbjct: 837 YWDMSNQDVIKAI-EEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKMIR 895 Query: 331 SKGGGMIPDGQSS 293 + P G S Sbjct: 896 NPSSLKTPLGTCS 908
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/133 (27%), Positives = 66/133 (49%), Gaps = 4/133 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ + P Sbjct: 772 FGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERP 831 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y D+S DV A+ + R P CP+ +M CW +RP +++V +++ + Sbjct: 832 YWDMSNQDVIKAI-EEGYRLPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGILDKMIR 890 Query: 331 SKGGGMIPDGQSS 293 + P G S Sbjct: 891 NPNSLKTPLGTCS 903
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 795 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSYGERP 854 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +++ DV AV + R P CP+A +M CW + + RP DE+V +++ L Sbjct: 855 YWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKL 911
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR+ N GA + + APE ++ + K DV+SFGI L EI +PYP Sbjct: 397 FGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYP 456 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 +S +V A+ H P P CP NIM +CW P++RP + + +++ T+ Sbjct: 457 GMSNPEVIRALEHGYRMPR-PDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTA 514
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/118 (30%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 658 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP 717 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +++ DV AV + R P CP+A +M CW + + RP DE+V +++ L Sbjct: 718 YWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKL 774
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 65.1 bits (157), Expect = 2e-10 Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 3/117 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG++R E TG + + APE L+ Y+ + DV+SFGI LWE + +PY Sbjct: 413 FGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGRYSSESDVWSFGILLWEAFSLGAVPY 472 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +LS A+ Q +R + P CP +M++CW+ +P +RP V Q + A+ Sbjct: 473 ANLSNQQTREAI-EQGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSFGAVHQDLIAI 528
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+ARV N GA + + APE ++ + K DV+SFGI L EI +PYP Sbjct: 399 FGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYP 458 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 +S +V A+ + R P CP NIM +CW P++RP + + +++ T+ Sbjct: 459 GMSNPEVIRAL-ERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTA 516
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 822 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 3/117 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PY 509 FG++R EA +G + + + APE L+ Y+ + DV+SFGI LWE + PY Sbjct: 702 FGMSREEADGVYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPY 761 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 P+LS V + R P CP A +M +CW P +RP + Q ++++ Sbjct: 762 PNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSI 817
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 65.1 bits (157), Expect = 2e-10 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 2/109 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYP 506 FG++R E +G + + APE L+ Y+ + DV+SFGI LWE + + PYP Sbjct: 703 FGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYP 762 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 ++ V + R P+ CP + IM KCWD P+ RP E+ Sbjct: 763 GMTNQQAREQV-ERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSEL 810
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAP 1282 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 65.1 bits (157), Expect = 2e-10 Identities = 35/118 (29%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ +G + + APE + + + DV+S+GI +WE+ + P Sbjct: 759 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGERP 818 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +LS +V A+ + R P CPSA +M +CW +RP ++V +++ L Sbjct: 819 YWELSNHEVMKAI-NDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKL 875
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R +P D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 772 FGLSRFLEDDPSDPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYG 830 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +AV Q+ R P CP+A +M CW + + RP ++V ++ Sbjct: 831 ERPYWDMSNQDVINAV-EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDK 889 Query: 340 L 338 L Sbjct: 890 L 890
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/118 (30%), Positives = 61/118 (51%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 819 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP 878 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +++ DV AV + R P CP+A +M CW + RP DE+V +++ L Sbjct: 879 YWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKL 935
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 3/117 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG++R E TG + + APE L+ Y+ + DV+SFGI LWE + +PY Sbjct: 753 FGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGWYSSESDVWSFGILLWEAFSLGAVPY 812 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +LS A+ Q +R + P CP +M++CW+ +P +RP V Q + A+ Sbjct: 813 ANLSNQQTREAI-EQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIAI 868
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 64.7 bits (156), Expect = 2e-10 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 5/114 (4%) Frame = -3 Query: 679 FGVARVEAQN----PKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DM 515 FG+AR P+ A + +M+PE D + K DV+SFGICL+EI+ + Sbjct: 340 FGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFTLGQL 399 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 PYPD+ + +H R P+ C ++M+ CW P+ RP+ V+ Sbjct: 400 PYPDVPSERIYE-YMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVE 452
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 FGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1340
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1223 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1282 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1283 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1340
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Frame = -3 Query: 679 FGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 FG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1224 FGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAP 1283 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + A+ Sbjct: 1284 PYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1341
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 64.7 bits (156), Expect = 2e-10 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R +P D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 777 FGLSRFLEDDPSDPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYG 835 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +AV Q+ R P CP+A +M CW + + RP ++V ++ Sbjct: 836 ERPYWDMSNQDVINAV-EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDK 894 Query: 340 L 338 L Sbjct: 895 L 895
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/133 (27%), Positives = 66/133 (49%), Gaps = 4/133 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ + P Sbjct: 777 FGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERP 836 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y D+S DV A + + R P CP+ +M CW +RP +++V +++ + Sbjct: 837 YWDMSNQDVIKA-IEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIR 895 Query: 331 SKGGGMIPDGQSS 293 + P G S Sbjct: 896 NPSSLKTPLGTCS 908
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/133 (27%), Positives = 66/133 (49%), Gaps = 4/133 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ + P Sbjct: 777 FGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERP 836 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y D+S DV A + + R P CP+ +M CW +RP +++V +++ + Sbjct: 837 YWDMSNQDVIKA-IEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIR 895 Query: 331 SKGGGMIPDGQSS 293 + P G S Sbjct: 896 NPNSLKTPLGTCS 908
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 64.3 bits (155), Expect = 3e-10 Identities = 42/131 (32%), Positives = 62/131 (47%), Gaps = 7/131 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+AR ++P + A L +MAPE + K Y + DV+SFG+ +WEI+ PY Sbjct: 1022 FGLARDVYKDPDYVRKGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFSLGASPY 1081 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ----LMEA 341 P L + + + R P S M CW G P +RP E+V+ L++A Sbjct: 1082 PGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGDLLQA 1141 Query: 340 LDTSKGGGMIP 308 +G IP Sbjct: 1142 SVQQEGKHYIP 1152
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 4/123 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + +PE + + + DV+S+GI LWE+ + P Sbjct: 765 FGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGERP 824 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y +S DV AV + P P CP+A +M CW + + RP +++V +++ L Sbjct: 825 YSQMSNQDVIKAVDERYRLPP-PMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883 Query: 331 SKG 323 + G Sbjct: 884 NPG 886
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/118 (29%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + +PE + + + D +S+GI LWE+ + P Sbjct: 765 FGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDAWSYGIVLWEVMSYGERP 824 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y ++SF DV AV + R P CP+A +M CW + + RP +++V +++ L Sbjct: 825 YWEMSFQDVIKAV-DEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 64.3 bits (155), Expect = 3e-10 Identities = 43/137 (31%), Positives = 63/137 (45%), Gaps = 1/137 (0%) Frame = -3 Query: 640 MTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQ 464 M+G + L + APE L ++ DV+SFGI +WE+ + PY D+S DV AV Sbjct: 804 MSGRSPAL-WAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAV-ED 861 Query: 463 NLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGGGMIPDGQSSGCL 284 R PR CP+ +M CW +P +RP ++ ++ M+ D + C Sbjct: 862 GFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSK--------MVQDPEPPKCA 913 Query: 283 CFTRARGP*TLCTALFS 233 T R P L FS Sbjct: 914 LTTCPRPPTPLADRAFS 930
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P TG + + APE + + ++ DV+SFG+ +WE+ + P Sbjct: 779 FGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERP 838 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +++ DV S+V + R P CP A +M CW + +RP ++V +++AL Sbjct: 839 YWNMTNRDVISSV-EEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDAL 895
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 63.9 bits (154), Expect = 4e-10 Identities = 41/121 (33%), Positives = 61/121 (50%), Gaps = 2/121 (1%) Frame = -3 Query: 679 FGVARV-EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+ARV + + + TGA + + APE + K DV+SFG+ L+EI PYP Sbjct: 378 FGLARVIDEEIYEAHTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGRFPYP 437 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 326 ++ +V + QN R P CP F +IM CW +P RP + + +E S+ Sbjct: 438 GMTNPEVLEKI-QQNYRMPCPANCPKQFHDIMLDCWREDPASRPTFETLQWQLEEFFNSE 496 Query: 325 G 323 G Sbjct: 497 G 497
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC 2.7.10.2)| (C-FES) Length = 820 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PY 509 FG++R EA +G + + APE L+ Y+ + DV+SFGI LWE + PY Sbjct: 700 FGMSREEADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPY 759 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 P+LS V + R P CP A +M +CW P +RP + Q ++++ Sbjct: 760 PNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSI 815
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 63.9 bits (154), Expect = 4e-10 Identities = 37/116 (31%), Positives = 58/116 (50%), Gaps = 2/116 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYP 506 FG++R E +G + + APE L+ Y+ + DV+SFGI LWE + + PYP Sbjct: 204 FGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYP 263 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 ++ V + R P+ CP IM KCWD P+ RP ++ + + A+ Sbjct: 264 GMTNQQAREQV-ERGYRMSAPQNCPEEIFTIMMKCWDYKPENRPKFSDLHKELTAI 318
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/118 (29%), Positives = 62/118 (52%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 821 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERP 880 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +++ DV AV + R P CP+A +M CW + + RP D++V +++ L Sbjct: 881 YWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKL 937
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/93 (37%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MA E L ++ K D++SFGI +WEI PYP +S ADV V R + P Sbjct: 653 WMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKV-RDGYRLEKPEH 711 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 C NIM CW +P +RP E++Q+++ L Sbjct: 712 CRRELYNIMYYCWSHDPQERPLFAEIIQMLDKL 744
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 63.5 bits (153), Expect = 6e-10 Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R +P D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 767 FGLSRFLEDDPADPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYG 825 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +AV Q+ R P CP+A +M CW + + RP ++V ++ Sbjct: 826 ERPYWDMSNQDVINAV-EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTLDK 884 Query: 340 L 338 L Sbjct: 885 L 885
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (CD333 antigen) Length = 806 Score = 63.5 bits (153), Expect = 6e-10 Identities = 46/151 (30%), Positives = 69/151 (45%), Gaps = 21/151 (13%) Frame = -3 Query: 679 FGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG+AR + N K T + +MAPE L + Y + DV+SFG+ LWEI+ P Sbjct: 636 FGLAR-DVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSP 694 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 YP + ++ ++ + R D P C IMR+CW P +RP ++V+ ++ + T Sbjct: 695 YPGIPVEELFK-LLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLT 753 Query: 331 -----------------SKGGGMIPDGQSSG 290 S GG P SSG Sbjct: 754 VTSTDEYLDLSAPFEQYSPGGQDTPSSSSSG 784
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 63.5 bits (153), Expect = 6e-10 Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + +PE + + DV+S+GI LWE+ + P Sbjct: 766 FGLSRVLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFTSASDVWSYGIVLWEVMSYGERP 825 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y ++S DV AV + R +P CP+A +M CW + + RP +++V +++ L Sbjct: 826 YWEMSNQDVIKAV-DEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 884 Query: 331 SKG 323 + G Sbjct: 885 NPG 887
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 2/119 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR+ N GA + + APE ++ + K DV+SFGI L EI +PYP Sbjct: 376 FGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYP 435 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 +S +V A+ H P P CP +IM +CW P++RP + + +++ T+ Sbjct: 436 GMSNPEVIRALEHGYRMPR-PDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTA 493
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 63.2 bits (152), Expect = 7e-10 Identities = 36/121 (29%), Positives = 60/121 (49%), Gaps = 1/121 (0%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPD 503 FG+AR+ GA + + APE + + K DV+SFG+ L I +PYP Sbjct: 372 FGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMVIVTYGRVPYPG 431 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 +S +V ++ H P C P + +I+ +CW G P++RP + + ++E T+ Sbjct: 432 MSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATE 491 Query: 322 G 320 G Sbjct: 492 G 492
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 63.2 bits (152), Expect = 7e-10 Identities = 42/140 (30%), Positives = 67/140 (47%), Gaps = 7/140 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R N D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 331 FGLSRFLDDNSSDPT-YTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFG 389 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +AV Q+ R P CP+ +M +CW + RP ++V ++ Sbjct: 390 ERPYWDMSNQDVMNAV-EQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVSTLDK 448 Query: 340 LDTSKGGGMIPDGQSSGCLC 281 + + SG LC Sbjct: 449 FLRNAASLKVLTSTHSGDLC 468
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 63.2 bits (152), Expect = 7e-10 Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + +PE + + + DV+S+GI LWE+ + P Sbjct: 765 FGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERP 824 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y ++S DV AV + R P CP+A +M CW + + RP +++V +++ L Sbjct: 825 YWEMSNQDVIKAV-DEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883 Query: 331 SKG 323 + G Sbjct: 884 NPG 886
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 63.2 bits (152), Expect = 7e-10 Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE L + K D +SFG+ LWEI+ MPYP + +V + N R D PR Sbjct: 685 WMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGN-RMDPPRN 743 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 CP IM +CW P+ RPD +++ ++ Sbjct: 744 CPGPVYRIMTQCWQHQPELRPDFGSILERIQ 774
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 63.2 bits (152), Expect = 7e-10 Identities = 44/135 (32%), Positives = 64/135 (47%), Gaps = 15/135 (11%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ LWEI+ PYP + ++ ++ Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFK-LL 713 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDEVVQL---MEALDTS--- 329 + R D P C + +MR CW P +RP D+D +V L E LD S Sbjct: 714 KEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSIPL 773 Query: 328 -KGGGMIPDGQSSGC 287 + PD +SS C Sbjct: 774 DQYSPSFPDTRSSTC 788
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 63.2 bits (152), Expect = 7e-10 Identities = 44/135 (32%), Positives = 64/135 (47%), Gaps = 15/135 (11%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ LWEI+ PYP + ++ ++ Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFK-LL 713 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDEVVQL---MEALDTS--- 329 + R D P C + +MR CW P +RP D+D +V L E LD S Sbjct: 714 KEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPL 773 Query: 328 -KGGGMIPDGQSSGC 287 + PD +SS C Sbjct: 774 DQYSPSFPDTRSSTC 788
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 63.2 bits (152), Expect = 7e-10 Identities = 46/152 (30%), Positives = 69/152 (45%), Gaps = 22/152 (14%) Frame = -3 Query: 679 FGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC--CDM 515 FG+AR + N K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 630 FGLAR-DVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPS 688 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 PYP + ++ ++ + R D P C IMR+CW P +RP ++V+ ++ + Sbjct: 689 PYPGIPVEELFK-LLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRIL 747 Query: 334 T-----------------SKGGGMIPDGQSSG 290 T S GG P SSG Sbjct: 748 TVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSG 779
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 62.8 bits (151), Expect = 9e-10 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 3/95 (3%) Frame = -3 Query: 613 YMAPEVLDGKPYN---RKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIP 443 ++APE L KP + R D++SF + LWE+ ++P+ DLS ++ V + LRP IP Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIP 414 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +M+ C + +P KR D +V ++E + Sbjct: 415 PGISPHVCKLMKICMNEDPAKRSKFDMIVPILEKM 449
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 62.8 bits (151), Expect = 9e-10 Identities = 39/110 (35%), Positives = 58/110 (52%), Gaps = 5/110 (4%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG----YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-M 515 FG+ARV + +D+ + + + APE + ++ K DV+SFGI L+EI M Sbjct: 373 FGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKM 432 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMD 365 PY ++ A V + QN R P CP F NIM +CW+ P +RP + Sbjct: 433 PYSGMTGAQVIQMLA-QNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFE 481
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 62.8 bits (151), Expect = 9e-10 Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 9/116 (7%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGT--------LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 FG++R+ MTG T T + + APE L ++ K DV++FG+ LWEI Sbjct: 331 FGLSRL-------MTGDTYTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIAT 383 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 M PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Sbjct: 384 YGMSPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 62.8 bits (151), Expect = 9e-10 Identities = 39/119 (32%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR+ N GA + + APE ++ K DV+SFGI L EI +PYP Sbjct: 377 FGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIPYP 436 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 +S +V A+ + R P CP NIM +CW P++RP + + +++ T+ Sbjct: 437 GMSNPEVIRAL-ERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTA 494
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 681 FGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYG 739 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP E+V ++ Sbjct: 740 ERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDK 798 Query: 340 L 338 + Sbjct: 799 M 799
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 2/119 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYP 506 FG+AR ++ GA + + APE L ++ K DV++FG+ LWEI M PYP Sbjct: 451 FGLARFMKEDTYTAHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYP 510 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 + ++V ++ R D P+ CP + +M +CW+ +P RP ++ +E L +S Sbjct: 511 GVELSNV-YGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISS 568
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/121 (31%), Positives = 64/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 763 FGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFG 821 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP + E+V ++ Sbjct: 822 ERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDK 880 Query: 340 L 338 + Sbjct: 881 M 881
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG++R EA +G + + APE L+ Y+ + DV+SFGI LWE + PY Sbjct: 357 FGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPY 416 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 P+LS + V + R P CP A +M +CW P +RP Q ++++ Sbjct: 417 PNLS-NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQELQSI 472
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/118 (30%), Positives = 61/118 (51%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++R +P+ G + + APE + + ++ DV+SFG+ +WE+ + P Sbjct: 146 FGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERP 205 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +++ DV S+V + R P CP A +M CW + +RP VV ++EAL Sbjct: 206 YWNMTNQDVISSV-EEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEAL 262
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/120 (32%), Positives = 62/120 (51%), Gaps = 4/120 (3%) Frame = -3 Query: 679 FGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG+AR + N K T + +MAPE L + Y + DV+SFG+ LWEI+ P Sbjct: 630 FGLAR-DVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSP 688 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 YP + ++ ++ + R D P C IMR+CW P +RP ++V+ ++ + T Sbjct: 689 YPGIPVEELFK-LLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLT 747
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 62.4 bits (150), Expect = 1e-09 Identities = 42/122 (34%), Positives = 62/122 (50%), Gaps = 2/122 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYP 506 FG+ARV N GA + + APE ++ + K DV+SFGI L+EI +PYP Sbjct: 385 FGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 444 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 326 + ADV SA + Q R CP +IM+ CW ++RP D + +++ T+ Sbjct: 445 GRTNADVMSA-LSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTAT 503 Query: 325 GG 320 G Sbjct: 504 EG 505
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 763 FGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFG 821 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP E+V ++ Sbjct: 822 ERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDK 880 Query: 340 L 338 + Sbjct: 881 M 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 763 FGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFG 821 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP E+V ++ Sbjct: 822 ERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDK 880 Query: 340 L 338 + Sbjct: 881 M 881
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 62.0 bits (149), Expect = 2e-09 Identities = 43/131 (32%), Positives = 65/131 (49%), Gaps = 7/131 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPY 509 FG+AR +NP + G T L +MAPE + K Y+ K DV+S+G+ LWEI+ PY Sbjct: 1041 FGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPY 1100 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ----LMEA 341 P + + + + + +R P IM CW +P +RP E+V+ L++A Sbjct: 1101 PGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQA 1160 Query: 340 LDTSKGGGMIP 308 G IP Sbjct: 1161 NVQQDGKDYIP 1171
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 62.0 bits (149), Expect = 2e-09 Identities = 40/115 (34%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +MAPE L + D++SFG+ LWEI + PY Sbjct: 1178 FGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPY 1237 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 LS V V+ D P CP ++MR CW NP RP E+V L++ Sbjct: 1238 QGLSNEQVLKFVMDGGYL-DQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK 1291
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 62.0 bits (149), Expect = 2e-09 Identities = 35/90 (38%), Positives = 45/90 (50%), Gaps = 6/90 (6%) Frame = -3 Query: 625 GTLGYMAPEVLD---GKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLR 455 GTL YMAPE L+ KP K DVYSF + LW I+ PY + + R Sbjct: 188 GTLYYMAPEHLNDVNAKP-TEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNR 246 Query: 454 PD---IPRCCPSAFANIMRKCWDGNPDKRP 374 PD I CP ++M+ CW+ NP+ RP Sbjct: 247 PDVDDITEYCPREIISLMKLCWEANPEARP 276
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 773 FGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYG 831 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D++ DV +A+ Q+ R P CPSA +M CW + + RP ++V ++ Sbjct: 832 ERPYWDMTNQDVINAI-EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDK 890 Query: 340 L 338 + Sbjct: 891 M 891
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 62.0 bits (149), Expect = 2e-09 Identities = 43/131 (32%), Positives = 65/131 (49%), Gaps = 7/131 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPY 509 FG+AR +NP + G T L +MAPE + K Y+ K DV+S+G+ LWEI+ PY Sbjct: 1041 FGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPY 1100 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ----LMEA 341 P + + + + + +R P IM CW +P +RP E+V+ L++A Sbjct: 1101 PGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQA 1160 Query: 340 LDTSKGGGMIP 308 G IP Sbjct: 1161 NVQQDGKDYIP 1171
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC 2.7.10.1)| (FGFR-1) Length = 812 Score = 62.0 bits (149), Expect = 2e-09 Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 11/137 (8%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ LWEI+ PYP + ++ ++ Sbjct: 649 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFK-LL 707 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDEVVQL---MEALDTSKGG 320 + R D P C + +M+ CW P +RP D+D ++ L E LD S Sbjct: 708 KEGHRMDKPTNCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRILALSSNQEYLDLS--- 764 Query: 319 GMIPDGQSSGCLCFTRA 269 +P Q S C TR+ Sbjct: 765 --MPVNQYSPCFPDTRS 779
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 62.0 bits (149), Expect = 2e-09 Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 765 FGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYG 823 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D++ DV +A+ Q+ R P CPSA +M CW + + RP ++V ++ Sbjct: 824 ERPYWDMTNQDVINAI-EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDK 882 Query: 340 L 338 + Sbjct: 883 M 883
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 62.0 bits (149), Expect = 2e-09 Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNL 458 GA + + APE L ++ K DV++FG+ LWEI M PYP + + V ++ + Sbjct: 444 GAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD-LLEKGY 502 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 R + P CP +MR CW +P RP E Q E + Sbjct: 503 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETM 542
>YS3J_CAEEL (Q19238) Putative tyrosine-protein kinase F09A5.2 in chromosome X (EC| 2.7.10.1) Length = 894 Score = 62.0 bits (149), Expect = 2e-09 Identities = 40/131 (30%), Positives = 65/131 (49%), Gaps = 4/131 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPD 503 FG+ R G + +M+ E L ++ K DV+SFG+ L+EI+ D+PYP Sbjct: 672 FGLCRYMDSALYTAKGGRLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGDVPYPT 731 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV---VQLMEALDT 332 + D+ ++ R P CP+ NIM+KCW P+ RP+ +E+ + +M LD Sbjct: 732 IQQVDMLEHLLAGG-RLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEITVMLNLDD 790 Query: 331 SKGGGMIPDGQ 299 G + + Q Sbjct: 791 ESYGYLSVESQ 801
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 6/120 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-----GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-D 518 FG++R +N D T G ++ + APE + + + D +S+GI +WE+ + Sbjct: 759 FGLSRFLEENSSDPTYTSSLGGKISIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGE 818 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PY D+S DV +A+ Q+ R P CP++ +M CW + + RP +VV ++ + Sbjct: 819 RPYWDMSNQDVINAI-EQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/122 (33%), Positives = 63/122 (51%), Gaps = 2/122 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+ARV N GA + + APE ++ + K DV+SFGI L+EI +PYP Sbjct: 385 FGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 444 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 326 + ADV +A+ Q R CP +IM+ CW + ++RP D + +++ T+ Sbjct: 445 GRTNADVMTAL-SQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDDFYTAT 503 Query: 325 GG 320 G Sbjct: 504 EG 505
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 61.6 bits (148), Expect = 2e-09 Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 2/122 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYP 506 FG+ARV N GA + + APE ++ + K DV+SFGI L+EI +PYP Sbjct: 385 FGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYP 444 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 326 + ADV +A+ P + CP +IM+ CW ++RP D + +++ T+ Sbjct: 445 GRTNADVMTALSQGYRMPRVEN-CPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTAT 503 Query: 325 GG 320 G Sbjct: 504 EG 505
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 57/117 (48%), Gaps = 3/117 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PY 509 FG++R A +G + + APE L+ Y+ + DV+SFGI LWE + PY Sbjct: 489 FGMSREAADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPY 548 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 P+LS V + R P CP A +M +CW P +RP + Q ++++ Sbjct: 549 PNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSI 604
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/121 (31%), Positives = 65/121 (53%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARV---EAQNPKDMTGATGT---LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R +A NP TGA G + + APE + + + DV+S+GI +WE+ Sbjct: 781 FGLSRFLEDDASNPT-YTGALGCKIPIRWTAPEAVQYRKFTSSSDVWSYGIVMWEVMSYG 839 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +A + Q+ R P CP+ +M CW + +RP +++V ++ Sbjct: 840 ERPYWDMSNQDVINA-IDQDYRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIVSALDK 898 Query: 340 L 338 + Sbjct: 899 M 899
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 61.6 bits (148), Expect = 2e-09 Identities = 43/131 (32%), Positives = 65/131 (49%), Gaps = 7/131 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPY 509 FG+AR +NP + G T L +MAPE + K Y+ K DV+S+G+ LWEI+ PY Sbjct: 1041 FGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPY 1100 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ----LMEA 341 P + + + + + +R P IM CW +P +RP E+V+ L++A Sbjct: 1101 PGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQA 1160 Query: 340 LDTSKGGGMIP 308 G IP Sbjct: 1161 NVQQDGKDYIP 1171
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 753 FGLSRFLENSRSDPT-YTSALGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMSYG 811 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +A+ Q+ R P CPSA +M CW + + RP ++V ++ Sbjct: 812 ERPYWDMSNQDVINAI-EQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDK 870 Query: 340 L 338 L Sbjct: 871 L 871
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 2/119 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR+ ++ + GA + + APE + ++ K DV+SFGI L E+ +PYP Sbjct: 389 FGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYP 448 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 ++ A+V + V H P P C P + IM +CW +P +RP + + +E TS Sbjct: 449 GMTNAEVLTQVEHGYRMPQPPNCEPRLY-EIMLECWHKDPMRRPTFETLQWKLEDFYTS 506
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/121 (30%), Positives = 63/121 (52%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R +N D T T +LG + APE + + + D +S+GI +WE+ Sbjct: 759 FGLSRFLEENSSDPT-YTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFG 817 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D+S DV +A+ Q+ R P CP++ +M CW + + RP +VV ++ Sbjct: 818 ERPYWDMSNQDVINAI-EQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDK 876 Query: 340 L 338 + Sbjct: 877 M 877
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 764 FGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 823 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y D+S DV A+ + R P CP A +M CW + RP ++V +++ L Sbjct: 824 YWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSMLDKL 880
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/95 (35%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -3 Query: 619 LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIP 443 L +MAPE + Y DV+SFGI LWEI+ PYP+L D + + R P Sbjct: 866 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQP 925 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 IM+KCW+ + RP ++V L+E L Sbjct: 926 AHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERL 960
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 61.2 bits (147), Expect = 3e-09 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + D++SFG+ LWEI + PY Sbjct: 1179 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPY 1238 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 LS V V+ D P CP ++MR CW NP RP E+V L++ Sbjct: 1239 QGLSNEQVLKFVMDGGYL-DPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1292
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Frame = -3 Query: 625 GTLGYMAPEVLD---GKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLR 455 GTL YMAPE L+ KP K DVYSFGI LW I+ PY ++ + + R Sbjct: 189 GTLYYMAPEHLNDINAKP-TEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNR 247 Query: 454 PDIPRC---CPSAFANIMRKCWDGNPDKRP 374 P++ CP ++M +CW P+ RP Sbjct: 248 PNVEEILEYCPREIISLMERCWQAIPEDRP 277
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/95 (35%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -3 Query: 619 LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIP 443 L +MAPE + Y DV+SFGI LWEI+ PYP+L D + + R P Sbjct: 866 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRMAQP 925 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 IM+KCW+ + RP ++V L+E L Sbjct: 926 AHASDEIYEIMQKCWEEKFETRPPFSQLVLLLERL 960
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/120 (29%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG-TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYP 506 FG+AR + +G T + + PEVL+ ++ K DV+++G+ +WEI+ C MPY Sbjct: 666 FGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYG 725 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD----MDEVVQLMEAL 338 L +V V + + + P+ C ++M+ CW P++RP MD++ + + L Sbjct: 726 RLKNTEVVER-VQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTL 784
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/110 (37%), Positives = 54/110 (49%), Gaps = 3/110 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+AR +N G L +MAPE L + + DV+SFGI +WEI PY Sbjct: 2103 FGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPY 2162 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 P S DV + V R + PR CP N+M +CW PD+RP + Sbjct: 2163 PAHSNLDVLN-YVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 61.2 bits (147), Expect = 3e-09 Identities = 43/135 (31%), Positives = 64/135 (47%), Gaps = 15/135 (11%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ LWEI+ P P + ++ ++ Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPNPGVPVEELFK-LL 713 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDEVVQL---MEALDTS--- 329 + R D P C + +MR CW+ P +RP D+D +V L E LD S Sbjct: 714 KEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPL 773 Query: 328 -KGGGMIPDGQSSGC 287 + PD +SS C Sbjct: 774 DQDSPSFPDTRSSTC 788
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 61.2 bits (147), Expect = 3e-09 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ +WEI+ PYP + ++ ++ Sbjct: 660 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LL 718 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 + R D P C + +MR CW P +RP ++V+ ++ + T Sbjct: 719 KEGHRMDKPANCTNELYMMMRDCWQAVPSQRPTFKQLVEDLDRILT 764
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 61.2 bits (147), Expect = 3e-09 Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 2/89 (2%) Frame = -3 Query: 619 LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNL-RPDI 446 + + APE ++ + DV++FG+CLWE++ P+ L+ + A+ N R + Sbjct: 304 IAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAIDAPNYQRLEQ 363 Query: 445 PRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 P CCPS + +M KCW + KRP E+ Sbjct: 364 PDCCPSEYYTLMMKCWQDDAAKRPRFGEI 392
>MOS_XENLA (P12965) Serine/threonine-protein kinase mos (EC 2.7.11.1)| (pp39-mos) Length = 359 Score = 61.2 bits (147), Expect = 3e-09 Identities = 33/99 (33%), Positives = 54/99 (54%), Gaps = 5/99 (5%) Frame = -3 Query: 625 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDI 446 GT + APE+L G+P K D+YSF I LW++ ++PY V AVV +LRP++ Sbjct: 235 GTYTHRAPELLKGEPVTAKADIYSFAITLWQMVSRELPYTG-DRQCVLYAVVAYDLRPEM 293 Query: 445 PRCCP-----SAFANIMRKCWDGNPDKRPDMDEVVQLME 344 A I++ CW P +RP+ +++++ +E Sbjct: 294 GPLFSHTEEGRAARTIVQSCWAARPQERPNAEQLLERLE 332
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 61.2 bits (147), Expect = 3e-09 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + D++SFG+ LWEI + PY Sbjct: 1168 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPY 1227 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 LS V V+ D P CP ++MR CW NP RP E+V L++ Sbjct: 1228 QGLSNEQVLKFVMDGGYL-DPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1281
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/125 (33%), Positives = 58/125 (46%), Gaps = 4/125 (3%) Frame = -3 Query: 679 FGVARV---EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MP 512 FG+ARV + NP++ G + + APE + K DV+SFG+ + EI MP Sbjct: 205 FGLARVIKEDIYNPRE--GTKFPIKWTAPEAALYNRFTIKSDVWSFGVLISEIVTHGRMP 262 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 YP ++ V AV + R P CP IM CW PD RP + + L+E Sbjct: 263 YPGMTNRQVLEAV-DRGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPTFESLKNLLEDYYV 321 Query: 331 SKGGG 317 S G Sbjct: 322 SAAEG 326
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 60.8 bits (146), Expect = 4e-09 Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 766 FGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYG 824 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D++ DV +A+ Q+ R P CP+A +M CW + + RP ++V ++ Sbjct: 825 ERPYWDMTNQDVINAI-EQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDK 883 Query: 340 L 338 + Sbjct: 884 M 884
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 60.8 bits (146), Expect = 4e-09 Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 783 FGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYG 841 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY D++ DV +A+ Q+ R P CP+A +M CW + + RP ++V ++ Sbjct: 842 ERPYWDMTNQDVINAI-EQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDK 900 Query: 340 L 338 + Sbjct: 901 M 901
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ + Sbjct: 595 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQL 654 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY +++ D +V + L PD+ + CP A +M +C D+RP +++ + Sbjct: 655 PYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASI 714 Query: 346 EALDTS 329 E L S Sbjct: 715 ELLARS 720
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ + Sbjct: 157 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQL 216 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY +++ D +V + L PD+ + CP A +M +C D+RP +++ + Sbjct: 217 PYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASI 276 Query: 346 EALDTS 329 E L S Sbjct: 277 ELLARS 282
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ + Sbjct: 635 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQL 694 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY +++ D +V + L PD+ + CP A +M +C D+RP +++ + Sbjct: 695 PYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASI 754 Query: 346 EALDTS 329 E L S Sbjct: 755 ELLARS 760
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ + Sbjct: 635 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQL 694 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY +++ D +V + L PD+ + CP A +M +C D+RP +++ + Sbjct: 695 PYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASI 754 Query: 346 EALDTS 329 E L S Sbjct: 755 ELLARS 760
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 765 FGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 824 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y D+S DV A+ + R P CP A +M CW RP ++V +++ L Sbjct: 825 YWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 765 FGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 824 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y D+S DV A+ + R P CP A +M CW RP ++V +++ L Sbjct: 825 YWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 765 FGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 824 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y D+S DV A+ + R P CP A +M CW RP ++V +++ L Sbjct: 825 YWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 764 FGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERP 823 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y D+S DV A+ + R P CP A +M CW RP ++V +++ L Sbjct: 824 YWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSMLDKL 880
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 60.8 bits (146), Expect = 4e-09 Identities = 34/98 (34%), Positives = 48/98 (48%), Gaps = 6/98 (6%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPYPDLSFADVSSAVVHQNLRPDIPR- 440 + APE K + K DV+S+GI ++EI PYPD+ +V V P+ + Sbjct: 385 WTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSKGYRMPNPEKF 444 Query: 439 ----CCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CCP IM CWD NP+KRP + + M+ L Sbjct: 445 ITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMDLL 482
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ + Sbjct: 221 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQL 280 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY +++ D +V + L PD+ + CP A +M +C D+RP +++ + Sbjct: 281 PYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASI 340 Query: 346 EALDTS 329 E L S Sbjct: 341 ELLARS 346
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 60.8 bits (146), Expect = 4e-09 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ G + + APE + + + DV+S+GI +WE+ + P Sbjct: 770 FGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVISYGERP 829 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y ++S DV AV + R P CP +M CW+ N RP ++V ++ L Sbjct: 830 YWEMSNQDVIKAV-DEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRL 886
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 60.8 bits (146), Expect = 4e-09 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ +WEI+ PYP + ++ ++ Sbjct: 658 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LL 716 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 + R D P C + +MR CW P +RP ++V+ ++ + T Sbjct: 717 KEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILT 762
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 60.8 bits (146), Expect = 4e-09 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ +WEI+ PYP + ++ ++ Sbjct: 658 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LL 716 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 + R D P C + +MR CW P +RP ++V+ ++ + T Sbjct: 717 KEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILT 762
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ + Sbjct: 205 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQL 264 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY +++ D +V + L PD+ + CP A +M +C D+RP +++ + Sbjct: 265 PYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASI 324 Query: 346 EALDTS 329 E L S Sbjct: 325 ELLARS 330
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 60.8 bits (146), Expect = 4e-09 Identities = 36/127 (28%), Positives = 64/127 (50%), Gaps = 13/127 (10%) Frame = -3 Query: 679 FGVARVEAQNP------KDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLW 536 FG++RV ++P +++TG + G + APE + + + DV+S+GI +W Sbjct: 139 FGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMW 198 Query: 535 EIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 E+ + PY D+S DV A+ + R P CP + +M CW +RP ++ Sbjct: 199 EVMSYGERPYWDMSNQDVIKAI-EEGYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQI 257 Query: 358 VQLMEAL 338 V +++ L Sbjct: 258 VNMLDKL 264
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 60.5 bits (145), Expect = 5e-09 Identities = 32/104 (30%), Positives = 54/104 (51%), Gaps = 1/104 (0%) Frame = -3 Query: 646 KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVV 470 K T + +MAPE L + Y + DV+SFG+ LWEI+ PYP + ++ ++ Sbjct: 653 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFK-LL 711 Query: 469 HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 + R D P C + +MR CW P +RP ++V+ ++ + Sbjct: 712 KEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 755
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 60.5 bits (145), Expect = 5e-09 Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++R +P+ G + + APE + + ++ DV+SFG+ +WE+ + P Sbjct: 778 FGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERP 837 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y +++ DV S+V + R P CP A +M CW + +RP VV +++AL Sbjct: 838 YWNMTNQDVISSV-EEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLDAL 894
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 60.5 bits (145), Expect = 5e-09 Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 1/88 (1%) Frame = -3 Query: 619 LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIP 443 L +M PE + ++ K DV+SFG+ +WE++ +MPY L+ +V + + + P Sbjct: 951 LRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQP 1010 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEV 359 CPS +M++CW +P RP E+ Sbjct: 1011 EGCPSRLTKLMQRCWAPSPKDRPSFSEL 1038
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 60.5 bits (145), Expect = 5e-09 Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 3/119 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY +PY Sbjct: 333 FGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPY 387 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 P + DV V + + D P CP A ++M+ C + RP ++ + +E + T Sbjct: 388 PRIPLKDVVPR-VEKGYKMDAPDGCPPAVYDVMKNCSHLDAATRPTFLQLREQLEHIKT 445
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 60.1 bits (144), Expect = 6e-09 Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 3/117 (2%) Frame = -3 Query: 679 FGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPY 509 FG+AR + + + T + +MAPE L K Y+ + DV+S+G+ LWEI D PY Sbjct: 883 FGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPY 942 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 P + A+ + + R + P C +MR+CW RP E+V+ + + Sbjct: 943 PHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDGI 999
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/111 (35%), Positives = 51/111 (45%), Gaps = 3/111 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + DV+SFG+ LWEI + PY Sbjct: 427 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPY 486 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 487 QGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 536
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 60.1 bits (144), Expect = 6e-09 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + K D +SFG+ LWEI+ MPYP S +V V R D P+ Sbjct: 1295 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGG-RMDPPKN 1353 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 CP IM +CW P+ RP+ +++ +E Sbjct: 1354 CPGPVYRIMTQCWQHQPEDRPNFAIILERIE 1384
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/111 (35%), Positives = 51/111 (45%), Gaps = 3/111 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + DV+SFG+ LWEI + PY Sbjct: 1155 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPY 1214 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 1215 QGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1264
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 60.1 bits (144), Expect = 6e-09 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + K D +SFG+ LWEI+ MPYP S +V V R D P+ Sbjct: 1299 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGG-RMDPPKN 1357 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 CP IM +CW P+ RP+ +++ +E Sbjct: 1358 CPGPVYRIMTQCWQHQPEDRPNFAIILERIE 1388
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/111 (35%), Positives = 51/111 (45%), Gaps = 3/111 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + DV+SFG+ LWEI + PY Sbjct: 1156 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPY 1215 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 1216 QGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1265
>EPHB6_RAT (P0C0K7) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) Length = 1013 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 5/122 (4%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNL 458 G++ L + APEV+ Y DV+SFGI +WE+ + PY D+S +V +A + Q Sbjct: 812 GSSSLLRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMSDQEVLNA-IEQEF 870 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL----DTSKGGGMIPDGQSSG 290 R P CP+ +M W + +RP D++V + + DT + G D S Sbjct: 871 RLPPPPGCPTGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGSSGDRPSQA 930 Query: 289 CL 284 L Sbjct: 931 LL 932
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 59.7 bits (143), Expect = 8e-09 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 3/95 (3%) Frame = -3 Query: 613 YMAPEVLDGKPYN---RKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIP 443 ++APE L KP + R D++SF + LWE+ ++P+ DLS ++ V + RP IP Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEG-RPTIP 413 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +M+ C + +P KRP D +V ++E + Sbjct: 414 PGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKM 448
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 59.7 bits (143), Expect = 8e-09 Identities = 39/111 (35%), Positives = 51/111 (45%), Gaps = 3/111 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + DV+SFG+ LWEI + PY Sbjct: 1154 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPY 1213 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 1214 QGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1263
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 59.7 bits (143), Expect = 8e-09 Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ TG + + APE + + ++ DV+S+GI +WE+ + P Sbjct: 816 FGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSYGIVMWEVMSYGERP 875 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y ++S DV + + + R P CP + +M CW + RP ++V ++ L Sbjct: 876 YWEMSNQDVILS-IEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKL 932
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 59.7 bits (143), Expect = 8e-09 Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE L + Y + DV+SFG+ +WEI+ PYP + ++ ++ + R D P Sbjct: 659 WMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDKPAN 717 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 C + +MR CW P RP ++V+ ++ + T Sbjct: 718 CTNELYMMMRDCWHAIPSHRPTFKQLVEDLDRILT 752
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 59.3 bits (142), Expect = 1e-08 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYP 506 FG+AR+ + GA + + APE L ++ K DV++FG+ LWEI M PYP Sbjct: 511 FGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYP 570 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + DV + + R + P CP ++MR+CW + RP + +E Sbjct: 571 AIDLTDVYHK-LDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALE 623
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 59.3 bits (142), Expect = 1e-08 Identities = 32/91 (35%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + K D +SFG+ LWEI+ MPYP + +V VV R D PR Sbjct: 689 WMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGG-RMDPPRG 747 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 CP IM +CW P+ RP +++ ++ Sbjct: 748 CPGPVYRIMTQCWQHEPELRPSFASILERLQ 778
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 59.3 bits (142), Expect = 1e-08 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPYPDLSFADVSSAVVHQNLRPDIPRC 437 + APE L+ Y CDV+S+GI +WEI+ D PY ++ + + R P+ Sbjct: 1226 WTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARER-IDTGYRMPTPKS 1284 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 P +M +CW + + RP DE+ +++AL Sbjct: 1285 TPEEMYRLMLQCWAADAESRPHFDEIYNVVDAL 1317
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 + APE L+ Y+ + DV+SFGI LWE + PYP+L+ + V + R P Sbjct: 724 WTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLT-NQQTREFVEKGHRLPCPEL 782 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP A +M +CW P +RP + Q + ++ Sbjct: 783 CPDAVFRLMEQCWAYEPGQRPSFSIICQELHSI 815
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 58.9 bits (141), Expect = 1e-08 Identities = 33/95 (34%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -3 Query: 619 LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIP 443 L +MAPE + Y DV+SFGI LWEI+ PYP+L + + + R P Sbjct: 867 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQP 926 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 IM+KCW+ + RP ++V L+E L Sbjct: 927 AHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERL 961
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 58.9 bits (141), Expect = 1e-08 Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ TG + + APE + + ++ D +S+GI +WE+ + P Sbjct: 816 FGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERP 875 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y ++S DV ++ + R P CP++ +M CW + RP ++V ++ L Sbjct: 876 YWEMSNQDVILSI-EEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKL 932
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 58.9 bits (141), Expect = 1e-08 Identities = 33/95 (34%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -3 Query: 619 LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIP 443 L +MAPE + Y DV+SFGI LWEI+ PYP+L + + + R P Sbjct: 867 LKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQP 926 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 IM+KCW+ + RP ++V L+E L Sbjct: 927 AHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERL 961
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/93 (34%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNL 458 G + + APE ++ ++ K DV+S+GI LWE++ D+PY +++ +V S + H Sbjct: 645 GGRWPVRWYAPESINYGTFSTKSDVWSYGITLWEMFTFGDLPYGEMTGNEVVSFLEHCG- 703 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 R + P CP +IM CW +P+KRP +E+ Sbjct: 704 RLEKPDECPIHTYSIMLSCWHIDPNKRPTFNEL 736
>MOS_MSVMM (P00537) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 376 Score = 58.5 bits (140), Expect = 2e-08 Identities = 36/105 (34%), Positives = 55/105 (52%), Gaps = 6/105 (5%) Frame = -3 Query: 625 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDI 446 GT + APE+L G+ K D+YSFGI LW++ ++PY V AVV NLRP + Sbjct: 269 GTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLRPSL 327 Query: 445 PRCCPSA------FANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 +A NI++ CW+ +RP + + + ++AL S Sbjct: 328 AGAVFTASLTGKTLQNIIQSCWEARALQRPGAELLQRDLKALADS 372
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/128 (32%), Positives = 63/128 (49%), Gaps = 4/128 (3%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE ++ + K DV+SFGI L EI +PYP Sbjct: 382 FGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 441 Query: 505 DLSFADVSSAVV--HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 ++ +V + ++ +RPD CP +MR CW P+ RP D + ++E T Sbjct: 442 GMTNPEVIQNLERGYRMVRPDN---CPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFT 498 Query: 331 SKGGGMIP 308 + G P Sbjct: 499 ATEGQYQP 506
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/118 (27%), Positives = 59/118 (50%), Gaps = 4/118 (3%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMP 512 FG++RV +P+ TG + + APE + + ++ D +S+GI +WE+ + P Sbjct: 816 FGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGERP 875 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 Y ++S DV ++ + R P CP + +M CW + RP ++V ++ L Sbjct: 876 YWEMSNQDVILSI-EEGYRLPAPMGCPPSLQQLMLHCWQKERNHRPKFTDIVSFLDKL 932
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 58.2 bits (139), Expect = 2e-08 Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 3/111 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + DV+SFG+ LWEI + PY Sbjct: 1150 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPY 1209 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 +S V V+ L + P CP +MR CW NP RP E++ Sbjct: 1210 QGMSNEQVLRFVMEGGLL-EKPDNCPDMLFELMRMCWQFNPKMRPSFLEII 1259
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 58.2 bits (139), Expect = 2e-08 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 2/126 (1%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE ++ + K DV+SFGI + EI +PYP Sbjct: 382 FGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILMTEIVTHGRIPYP 441 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 326 ++ +V + + R P CP +M +CW PD RP D + ++E T+ Sbjct: 442 GMTNPEVIQNL-ERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDFFTAT 500 Query: 325 GGGMIP 308 G P Sbjct: 501 EGQYQP 506
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/113 (30%), Positives = 55/113 (48%), Gaps = 2/113 (1%) Frame = -3 Query: 679 FGVARVEAQNPK-DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPYP 506 FG+AR + +GA + + PEV Y+ K DV+SFG+ +WE++ MP+ Sbjct: 409 FGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFE 468 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 + S V A + Q R P P +M CW +P RP E++Q++ Sbjct: 469 NKSNLQVVEA-ISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVL 520
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE + K DV+SFGI L E+ +PYP Sbjct: 415 FGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 474 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + +V V + R P+ CP + +MR+CW PD+RP + + +E Sbjct: 475 GMVNREVLEQV-DRGYRMPCPQGCPESLHEMMRQCWKKEPDERPTFEYIQSFLE 527
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 57.8 bits (138), Expect = 3e-08 Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 1/118 (0%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPD 503 FG+AR+ GA + + APE + + K DV+SFG+ L E+ +PYP Sbjct: 378 FGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPG 437 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTS 329 +S +V + P C P + ++ +CW P++RP + + ++E T+ Sbjct: 438 MSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTA 495
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 57.8 bits (138), Expect = 3e-08 Identities = 40/120 (33%), Positives = 60/120 (50%), Gaps = 2/120 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPD 503 FG++R E K G + +MA E L+ Y K DV+SFG+ LWEI PY Sbjct: 998 FGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCG 1056 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 ++ A++ + Q R + PR C +MR+CW P +RP ++ +QL L+ K Sbjct: 1057 MTCAELYEK-LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARK 1115
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 57.8 bits (138), Expect = 3e-08 Identities = 40/120 (33%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPD 503 FG++R E K G + +MA E L+ Y K DV+SFG+ LWEI PY Sbjct: 44 FGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCG 102 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 ++ A++ + Q R + PR C +MR+CW P +RP ++ VQL + K Sbjct: 103 MTCAELYEK-LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARK 161
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 57.8 bits (138), Expect = 3e-08 Identities = 35/112 (31%), Positives = 53/112 (47%), Gaps = 3/112 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+AR ++P + A L +MAPE + + Y + DV+SFG+ LWEI+ PY Sbjct: 1047 FGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPY 1106 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 P + + + + R P M CW G P +RP E+V+ Sbjct: 1107 PGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVE 1158
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/115 (32%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +M+PE L + DV+SFG+ LWEI + PY Sbjct: 1167 FGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPY 1226 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 LS V V+ D P CP ++M+ CW NP RP E++ +++ Sbjct: 1227 QGLSNEQVLKFVMDGGSL-DHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLK 1280
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 57.8 bits (138), Expect = 3e-08 Identities = 40/120 (33%), Positives = 60/120 (50%), Gaps = 2/120 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPD 503 FG++R E K G + +MA E L+ Y K DV+SFG+ LWEI PY Sbjct: 994 FGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCG 1052 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 ++ A++ + Q R + PR C +MR+CW P +RP ++ +QL L+ K Sbjct: 1053 MTCAELYEK-LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARK 1111
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 57.8 bits (138), Expect = 3e-08 Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 3/112 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+AR ++P + A L +MAPE + + Y + DV+SFG+ LWEI+ PY Sbjct: 1040 FGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPY 1099 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 P + + + + R P M CW G+P +RP E+V+ Sbjct: 1100 PGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTFSELVE 1151
>MOS_MSVMT (P32593) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 354 Score = 57.4 bits (137), Expect = 4e-08 Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 6/107 (5%) Frame = -3 Query: 625 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDI 446 GT + APE+L G+ K D+YSFGI LW++ ++PY V AVV NLRP + Sbjct: 249 GTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLRPSL 307 Query: 445 ------PRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 A NI++ CW+ +RP + + + ++A + G Sbjct: 308 AGAVFTASLTGKALQNIIQSCWEARGLQRPSAELLQRDLKAFRGTLG 354
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/122 (30%), Positives = 60/122 (49%), Gaps = 2/122 (1%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE ++ + K DV+SFGI L EI +PYP Sbjct: 381 FGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRIPYP 440 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSK 326 ++ +V + + R P CP +M +CW P++RP + + ++E T+ Sbjct: 441 GMTNPEVIQNL-ERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDFFTAT 499 Query: 325 GG 320 G Sbjct: 500 EG 501
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 57.4 bits (137), Expect = 4e-08 Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 6/107 (5%) Frame = -3 Query: 625 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDI 446 GT + APE+L G+ K D+YSFGI LW++ ++PY V AVV NLRP + Sbjct: 269 GTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLRPSL 327 Query: 445 ------PRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 A NI++ CW+ +RP + + + ++A + G Sbjct: 328 AGAVFTASLTGKALQNIIQSCWEARGLQRPSAELLQRDLKAFRGTLG 374
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/126 (29%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++ Sbjct: 162 FGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGEL 221 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY ++ D +V + PD+ R CP A ++ C ++RP +++ + Sbjct: 222 PYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAIKRLVADCVKKVKEERPLFPQILSSI 281 Query: 346 EALDTS 329 E L S Sbjct: 282 ELLQHS 287
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/126 (29%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++ Sbjct: 487 FGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGEL 546 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY ++ D +V + PD+ R CP A ++ C ++RP +++ + Sbjct: 547 PYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSI 606 Query: 346 EALDTS 329 E L S Sbjct: 607 ELLQHS 612
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/126 (29%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++ Sbjct: 487 FGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGEL 546 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY ++ D +V + PD+ R CP A ++ C ++RP +++ + Sbjct: 547 PYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSI 606 Query: 346 EALDTS 329 E L S Sbjct: 607 ELLQHS 612
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 57.4 bits (137), Expect = 4e-08 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE ++ + + DV+ FG+C+WEI + P+ + DV + + P P C Sbjct: 601 WMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIENGERLPMPPNC 660 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 661 PPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 697
>KRAF1_CAEEL (Q07292) Raf homolog serine/threonine-protein kinase (EC 2.7.11.1)| (Abnormal cell lineage protein 45) Length = 813 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 11/120 (9%) Frame = -3 Query: 679 FGVARVEAQ----NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCC 521 FG+A V+ + + TG++ +MAPEV+ D PY + DVYSFGIC++EI Sbjct: 622 FGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSS 681 Query: 520 DMPYPDLSFADVSSAVVHQN-LRPD---IPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 +PY +++ D +V + LRPD I P + + C + ++RP EV++ Sbjct: 682 HLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLE 741
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE ++ + + DV+ FG+C+WEI + P+ + DV + + P P C Sbjct: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 647 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 648 PPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE + K DV+SFGI L E+ +PYP Sbjct: 408 FGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVAKGRVPYP 467 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 468 GMVNREVLEQV-ERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFLE 520
>MOS_MSVMH (P07331) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 6/107 (5%) Frame = -3 Query: 625 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDI 446 GT + APE+L G+ K D+YSFGI LW++ ++PY V AVV NLRP + Sbjct: 269 GTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLRPSL 327 Query: 445 PRCCPSA------FANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 +A NI++ CW+ +RP + + + ++A + G Sbjct: 328 AGAVFTASLTGKTLQNIIQSCWEARALQRPGAELLQRDLKAFRGALG 374
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE ++ + + DV+ FG+C+WEI + P+ + DV + + P P C Sbjct: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 647 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 648 PPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE ++ + + DV+ FG+C+WEI + P+ + DV + + P P C Sbjct: 626 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 685 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 686 PPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 722
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 57.0 bits (136), Expect = 5e-08 Identities = 40/120 (33%), Positives = 60/120 (50%), Gaps = 2/120 (1%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPD 503 FG++R E K G + +MA E L+ Y K DV+SFG+ LWEI PY Sbjct: 996 FGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCG 1054 Query: 502 LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 ++ A++ + Q R + PR C +MR+CW P +RP ++ +QL L+ K Sbjct: 1055 MTCAELYEK-LPQAYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARK 1113
>MOS_MSVTS (P10421) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 342 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 6/107 (5%) Frame = -3 Query: 625 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDI 446 GT + APE+L G+ K D+YSFGI LW++ ++PY V AVV NLRP + Sbjct: 237 GTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLRPSL 295 Query: 445 PRCCPSA------FANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKG 323 +A NI++ CW+ +RP + + + ++A + G Sbjct: 296 TGAVFTASLTRKTLQNIIQNCWEARALQRPGAELLQRDLKAFRGALG 342
>EPHB6_MOUSE (O08644) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) (MEP) Length = 1014 Score = 57.0 bits (136), Expect = 5e-08 Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNL 458 G++ L + APEV+ Y DV+SFGI +WE+ + PY D++ +V +A + Q Sbjct: 813 GSSSLLRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMNEQEVLNA-IEQEF 871 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL----DTSKGGGMIPDGQSSG 290 R P CP +M W + +RP D++V + + DT + G D S Sbjct: 872 RLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGGSGDRPSQA 931 Query: 289 CL 284 L Sbjct: 932 LL 933
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/111 (31%), Positives = 52/111 (46%), Gaps = 3/111 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDMPY 509 FG+ R + G G L +MAPE L ++ DV+S+G+ LWE+ PY Sbjct: 1181 FGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLASQPY 1240 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 L+ V V+ + + P CP N+MR+CW P RP E++ Sbjct: 1241 QGLTNDQVLRYVIDGGVM-ERPENCPDNLYNLMRRCWQHRPTARPTFMEII 1290
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 57.0 bits (136), Expect = 5e-08 Identities = 31/98 (31%), Positives = 52/98 (53%), Gaps = 2/98 (2%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE ++ + + DV+ FG+C+WEI + P+ + DV + + P P C Sbjct: 588 WMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNC 647 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEALDTSK 326 P+ + ++M KCW +P +RP E+ QL L+ K Sbjct: 648 PPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTILEEEK 684
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 56.6 bits (135), Expect = 7e-08 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE + K DV+SFGI L E+ +PYP Sbjct: 412 FGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 471 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 472 GMVNREVLEQV-ERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLE 524
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 56.6 bits (135), Expect = 7e-08 Identities = 36/121 (29%), Positives = 61/121 (50%), Gaps = 7/121 (5%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 FG++R + D T T +LG + A E + + + DV+S+GI +WE+ Sbjct: 764 FGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYG 822 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 + PY +S DV +A+ Q+ R P CP+A +M CW + + RP + E+V + Sbjct: 823 ERPYWTMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRP 881 Query: 340 L 338 + Sbjct: 882 M 882
>NEK11_MOUSE (Q8C0Q4) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 628 Score = 56.6 bits (135), Expect = 7e-08 Identities = 33/109 (30%), Positives = 55/109 (50%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FGV+R+ + + T TGT YM+PE L + Y+ K D++S L+E+ C D + Sbjct: 177 FGVSRLLMGSCELATTLTGTPHYMSPEALKHQGYDAKSDIWSLACILYEMCCLDHAFAGS 236 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 SF V +V + P +P P IM + + +P RP ++++ Sbjct: 237 SFLSVVLNIV-EGKTPSLPDRYPRELNTIMERMLNKSPSLRPSAADILK 284
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 56.6 bits (135), Expect = 7e-08 Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + + + DV+SFG+ LWEI+ P+ LS +V + + + PR Sbjct: 724 WMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVL-ERPRV 782 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP +IM CW P +R ++ E+ +++ AL Sbjct: 783 CPKEVYDIMLGCWQREPQQRLNIKEIYKILHAL 815
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 56.6 bits (135), Expect = 7e-08 Identities = 36/126 (28%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++ Sbjct: 487 FGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGEL 546 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY ++ D +V + PD+ + CP A ++ C ++RP +++ + Sbjct: 547 PYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSI 606 Query: 346 EALDTS 329 E L S Sbjct: 607 ELLQHS 612
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 56.6 bits (135), Expect = 7e-08 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 4/128 (3%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE ++ + K DV+SFGI L EI +PYP Sbjct: 382 FGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 441 Query: 505 DLSFADVSSAVV--HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 ++ +V + ++ +RPD CP ++M CW P+ RP D + ++E T Sbjct: 442 GMTNPEVIQNLERGYRMVRPDN---CPEELYHLMMLCWKERPEDRPTFDYLRSVLEDFFT 498 Query: 331 SKGGGMIP 308 + G P Sbjct: 499 ATEGQYQP 506
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 56.6 bits (135), Expect = 7e-08 Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 2/114 (1%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE + K DV+SFGI L E+ +PYP Sbjct: 405 FGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYP 464 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 465 GMVNREVLEQV-ERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLE 517
>MOS_MOUSE (P00536) Proto-oncogene serine/threonine-protein kinase mos (EC| 2.7.11.1) (c-mos) (Oocyte maturation factor mos) Length = 390 Score = 56.6 bits (135), Expect = 7e-08 Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 6/90 (6%) Frame = -3 Query: 625 GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDI 446 GT + APE+L G+ K D+YSFGI LW++ ++PY V AVV NLRP + Sbjct: 285 GTYTHQAPEILKGEIATPKADIYSFGITLWQMTTREVPYSG-EPQYVQYAVVAYNLRPSL 343 Query: 445 PRCCPSA------FANIMRKCWDGNPDKRP 374 +A NI++ CW+ +RP Sbjct: 344 AGAVFTASLTGKTLQNIIQSCWEARALQRP 373
>NEK11_MACFA (Q8WNU8) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 637 Score = 56.2 bits (134), Expect = 9e-08 Identities = 32/110 (29%), Positives = 54/110 (49%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FGV+R+ + T TGT YM+PE L + Y+ K D++S L+E+ C + + Sbjct: 176 FGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGS 235 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQL 350 +F + +V + P +P P IM + NP RP E++++ Sbjct: 236 NFLSIVLKIVEGD-TPSLPERYPKELNTIMESMLNKNPSLRPSAIEILKI 284
>NTRK3_RAT (Q03351) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 864 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + + + DV+SFG+ LWEI+ P+ LS +V + + + PR Sbjct: 761 WMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVL-ERPRV 819 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP ++M CW P +R ++ E+ +++ AL Sbjct: 820 CPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 852
>NTRK3_HUMAN (Q16288) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 839 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + + + DV+SFG+ LWEI+ P+ LS +V + + + PR Sbjct: 736 WMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVL-ERPRV 794 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP ++M CW P +R ++ E+ +++ AL Sbjct: 795 CPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 827
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 56.2 bits (134), Expect = 9e-08 Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y + DV+S+GI LWEI+ + PYP + + +V + P Sbjct: 819 WMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVF 878 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 P +IM+ CWD P +RP ++ L++ Sbjct: 879 APKNIYSIMQSCWDLEPTRRPTFQQICFLLQ 909
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 56.2 bits (134), Expect = 9e-08 Identities = 36/126 (28%), Positives = 68/126 (53%), Gaps = 9/126 (7%) Frame = -3 Query: 679 FGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIYCCDM 515 FG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ ++ Sbjct: 487 FGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGEL 546 Query: 514 PYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PY ++ D +V + PD+ + CP A ++ C ++RP +++ + Sbjct: 547 PYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSI 606 Query: 346 EALDTS 329 E L S Sbjct: 607 ELLQHS 612
>NTRK3_SAIBB (Q5IS82) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + + + DV+SFG+ LWEI+ P+ LS +V + + + PR Sbjct: 722 WMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVL-ERPRV 780 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP ++M CW P +R ++ E+ +++ AL Sbjct: 781 CPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
>NTRK3_PIG (P24786) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C) Length = 825 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + + + DV+SFG+ LWEI+ P+ LS +V + + + PR Sbjct: 722 WMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVL-ERPRV 780 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP ++M CW P +R ++ E+ +++ AL Sbjct: 781 CPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
>NTRK3_PANTR (Q5IS37) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + + + DV+SFG+ LWEI+ P+ LS +V + + + PR Sbjct: 722 WMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVL-ERPRV 780 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP ++M CW P +R ++ E+ +++ AL Sbjct: 781 CPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
>NTRK3_MACFA (Q5IFJ9) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) Length = 825 Score = 56.2 bits (134), Expect = 9e-08 Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + + + DV+SFG+ LWEI+ P+ LS +V + + + PR Sbjct: 722 WMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVL-ERPRV 780 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP ++M CW P +R ++ E+ +++ AL Sbjct: 781 CPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 56.2 bits (134), Expect = 9e-08 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y DV+SFGI LWEI+ PYP + + R P Sbjct: 861 WMAPESIFDNLYTTLSDVWSFGILLWEIFSLGGTPYPGMIVDSTFYNKIKSGYRMAKPDH 920 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +IM KCW+ P+KRP + ++E+L Sbjct: 921 ATHEVYDIMVKCWNSEPEKRPSFRHLSDIVESL 953
>PGFRA_HUMAN (P16234) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) (CD140a antigen) Length = 1089 Score = 56.2 bits (134), Expect = 9e-08 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MAPE + Y DV+S+GI LWEI+ PYP + + R P Sbjct: 861 WMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDH 920 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 S IM KCW+ P+KRP + +++E L Sbjct: 921 ATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENL 953
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 1/99 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRC 437 +MA E L + + K DV+SFG+ +WE+ PYP++ D++ ++ P P+ Sbjct: 231 WMALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQ-PQP 289 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGG 320 CP +M CW P++RP +V +E + S G Sbjct: 290 CPDTLYGVMLSCWAPTPEERPSFSGLVCELERVLASLEG 328
>EPHB6_HUMAN (O15197) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) (HEP) Length = 1006 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/111 (31%), Positives = 55/111 (49%), Gaps = 5/111 (4%) Frame = -3 Query: 634 GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNL 458 G + L + APEV+ + DV+SFGI +WE+ + PY D+S +V +A + Q Sbjct: 805 GPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNA-IEQEF 863 Query: 457 RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL----DTSKGGG 317 R P CP +M W + +RP D++V + + DT + GG Sbjct: 864 RLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGG 914
>NTRK1_RAT (P35739) High affinity nerve growth factor receptor precursor (EC| 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (p140-TrkA) (Slow nerve growth factor receptor) (Trk-A) Length = 799 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYPDLSFADVSSAVVHQNLRPDIPRC 437 +M PE + + ++ + DV+SFG+ LWEI+ P+ LS + + Q + PR Sbjct: 696 WMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECIT-QGRELERPRA 754 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP IMR CW P +R M +V ++AL Sbjct: 755 CPPDVYAIMRGCWQREPQQRLSMKDVHARLQAL 787
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 3/112 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPY 509 FG+AR ++P + A L +MAPE + + Y + DV+SFG+ LWEI+ PY Sbjct: 1045 FGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPY 1104 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 P + + + + R P M CW +P++RP E+V+ Sbjct: 1105 PGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPSFSELVE 1156
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPD-LSFADVSSAVVHQNLRPDIPRC 437 +MAPE+++G+ Y+ K D++SFGI L EI PD L V L P Sbjct: 522 WMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPRTTDFGLNVRGFLERYCPPA 581 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 CP +F I C D +P+KRP ++ Q +E L Sbjct: 582 CPPSFFPIAACCCDLDPEKRPSFSKLEQWLETL 614
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 55.8 bits (133), Expect = 1e-07 Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 3/124 (2%) Frame = -3 Query: 679 FGVARV-EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+ARV + + + GA + + APE + K DV+SFGI L+E+ PYP Sbjct: 378 FGLARVIDEEIYEAKLGAKFPIKWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGRFPYP 437 Query: 505 DLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV-QLMEALDTS 329 ++ A V + Q+ R P CP IM CW +P RP + + QL E T Sbjct: 438 GMTNAQVLEQI-QQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTFETLSWQLEEFFTTG 496 Query: 328 KGGG 317 G Sbjct: 497 DDAG 500
>EGL15_CAEEL (Q10656) Myoblast growth factor receptor egl-15 precursor (EC| 2.7.10.1) (Egg-laying defective protein 15) Length = 1040 Score = 55.8 bits (133), Expect = 1e-07 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Frame = -3 Query: 613 YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRC 437 +MA E LD Y + DV+S+G+ LWEI PYP ++ ++ A + + R + P Sbjct: 840 WMALEALDSNVYTVESDVWSYGVLLWEIMTLGGTPYPTIAMPEL-YANLKEGYRMEPPHL 898 Query: 436 CPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 CP ++M CW ++RP +V ++ Sbjct: 899 CPQEVYHLMCSCWREKLEERPSFKTIVDYLD 929
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 55.8 bits (133), Expect = 1e-07 Identities = 41/144 (28%), Positives = 64/144 (44%), Gaps = 12/144 (8%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWE-IYCCDMPY 509 FG+ R + G G L +MAPE L + DV+S+G+ +WE + PY Sbjct: 1192 FGMTRDIYETDYYRKGGKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLAAQPY 1251 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ-LMEALDT 332 LS +V + + ++P CP+ A +M+ CW P++RP +++ L+ L Sbjct: 1252 QGLSNEEVVKFISDGYIM-ELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYLLPKLKP 1310 Query: 331 S--------KGGGMIPDGQSSGCL 284 S GG DG G L Sbjct: 1311 SFEKVSYFFTSGGGHTDGAGEGTL 1334
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 55.5 bits (132), Expect = 2e-07 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 3/115 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIY-CCDMPY 509 FG+ R + G G L +MAPE L + DV+SFG+ LWEI + PY Sbjct: 1134 FGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPY 1193 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 LS V V+ + ++ CP +M CW NP RP +++ ++ Sbjct: 1194 QGLSNEQVLKFVMDGGVLEEL-EDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQ 1247
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 55.5 bits (132), Expect = 2e-07 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 3/115 (2%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIY-CCDMPY 509 FG+ R + G G L +MAPE L + DV+SFG+ LWEI + PY Sbjct: 1134 FGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPY 1193 Query: 508 PDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 LS V V+ + ++ CP +M +CW NP RP ++ ++ Sbjct: 1194 QGLSNEQVLKFVMDGGVLEEL-EGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQ 1247
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 55.5 bits (132), Expect = 2e-07 Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 4/128 (3%) Frame = -3 Query: 679 FGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-MPYP 506 FG+AR +E GA + + APE ++ + K DV+SFGI L EI +PYP Sbjct: 382 FGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYP 441 Query: 505 DLSFADVSSAVV--HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 ++ +V + ++ +RPD CP ++M CW P+ RP D + +++ T Sbjct: 442 GMTNPEVIQNLERGYRMVRPDN---CPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFT 498 Query: 331 SKGGGMIP 308 + G P Sbjct: 499 ATEGQYQP 506
>NEK11_HUMAN (Q8NG66) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 645 Score = 55.5 bits (132), Expect = 2e-07 Identities = 32/110 (29%), Positives = 54/110 (49%) Frame = -3 Query: 679 FGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDL 500 FGV+R+ + T TGT YM+PE L + Y+ K D++S L+E+ C + + Sbjct: 176 FGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGS 235 Query: 499 SFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQL 350 +F + +V + P +P P IM + NP RP E++++ Sbjct: 236 NFLSIVLKIVEGD-TPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKI 284
>LIMK1_DROME (Q8IR79) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (dLIMK)| Length = 1257 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/120 (28%), Positives = 52/120 (43%) Frame = -3 Query: 667 RVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMPYPDLSFAD 488 R +++ + G +MAPE++ G Y+ K DV+SFGI L EI PD + Sbjct: 580 RSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGRVEADPDFMPRN 639 Query: 487 VSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDTSKGGGMIP 308 ++ Q R CP F + C D NPD RP + + ++ L +P Sbjct: 640 SDFSLNQQEFREKFCAQCPEPFVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAADRVP 699 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 106,161,135 Number of Sequences: 219361 Number of extensions: 2354056 Number of successful extensions: 8980 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 7932 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8430 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6712189044 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
