ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbaal19k06 |
|---|---|
| Clone Library Name | barley_pub |
>PM34_HUMAN (O43808) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 108 bits (269), Expect = 2e-23 Identities = 63/167 (37%), Positives = 98/167 (58%), Gaps = 7/167 (4%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 G I A ++ R+ GIS W G P+L++V NP+IQFM YE L ++L KR + Sbjct: 148 GIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKR-------MKL 200 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGR---NAASRYTGTLDAIL----K 261 ++++VF++GA+AK AT VTYPL V+S L+ GR N +R G+L IL + Sbjct: 201 SSLDVFIIGAVAKAIATTVTYPLQTVQSILR----FGRHRLNPENRTLGSLRNILYLLHQ 256 Query: 260 MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSR 120 +R G+ G YKG+ K++Q+V A+++F+V E+L ++ R Sbjct: 257 RVRRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKLTAATFTVMGLKR 303 Score = 46.6 bits (109), Expect = 7e-05 Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 3/164 (1%) Frame = -3 Query: 638 RLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQ 459 RL EK + T + E+ +E G+ ++G P + +C + + K L Sbjct: 34 RLRLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALW 93 Query: 458 SKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRN---AASRY 288 K ++ T + ++G +A + ++T PL VV +RL+ + RN + Y Sbjct: 94 VKG-------QHSTTGKDLVVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNY 146 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 G +DA ++IR EG+ + G ++ VF ++ FM E L Sbjct: 147 KGIIDAFHQIIRDEGISALWNGTFPSLL-LVFNPAIQFMFYEGL 189
>PM34_MOUSE (O70579) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 104 bits (260), Expect = 2e-22 Identities = 59/155 (38%), Positives = 93/155 (60%), Gaps = 7/155 (4%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 G I A ++ R+ GI W G P+L++V NP+IQFM YE L ++L KR + Sbjct: 148 GIIDAFHQIIRDEGILALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKR-------MKL 200 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGR---NAASRYTGTLDAILKMIRY 249 ++++VF++GAIAK AT VTYP+ V+S L+ GR N +R G+L +L ++ Sbjct: 201 SSLDVFIIGAIAKAIATTVTYPMQTVQSILR----FGRHRLNPENRTLGSLRNVLSLLHQ 256 Query: 248 E----GLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 G+ G YKG+ K++Q+V A+++F+V E+L Sbjct: 257 RVKRFGIMGLYKGLEAKLLQTVLTAALMFLVYEKL 291 Score = 44.3 bits (103), Expect = 3e-04 Identities = 42/164 (25%), Positives = 78/164 (47%), Gaps = 3/164 (1%) Frame = -3 Query: 638 RLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQ 459 RL EK + T + E+ +E G+ ++G P + +C + F+ + T + Sbjct: 34 RLRLQVDEKRKSKTTHAVLLEIIKEEGLLAPYRGWFPVISSLCCSN--FVYFYTFNSLKA 91 Query: 458 SKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNA---ASRY 288 G+R + T ++ ++G +A + ++T PL VV +RL+ + RN + Y Sbjct: 92 VWVKGQR----SSTGKDL-VVGFVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIIPTNY 146 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 G +DA ++IR EG+ + G ++ VF ++ FM E L Sbjct: 147 KGIIDAFHQIIRDEGILALWNGTFPSLL-LVFNPAIQFMFYEGL 189
>MFTC_MACFA (Q95J75) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 89.7 bits (221), Expect = 7e-18 Identities = 49/164 (29%), Positives = 88/164 (53%) Frame = -3 Query: 632 AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSK 453 A ++S + G + ++Y+ G+ G +KG +P L + ++QFM YE L +L+ Sbjct: 154 AVINSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELL--KLKYN 211 Query: 452 RSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 273 + R P+ ++ +E + A++K+ A TYP VV++RLQ + Y+G +D Sbjct: 212 QHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMF-------YSGVID 264 Query: 272 AILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 I K R EG+ GFYKG+ +++ A + F+V E + F++ Sbjct: 265 VITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFLL 308
>MFTC_HUMAN (Q9H2D1) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 89.0 bits (219), Expect = 1e-17 Identities = 47/153 (30%), Positives = 83/153 (54%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 G + ++Y+ G+ G +KG +P L + ++QFM YE L +L+ + R P+ + Sbjct: 165 GMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELL--KLKYNQHINRLPEAQL 222 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 + +E + A++K+ A TYP VV++RLQ + Y+G +D I K R EG+ Sbjct: 223 STVEYISVAALSKIFAVAATYPYQVVRARLQDQHMF-------YSGVIDVITKTWRKEGV 275 Query: 239 HGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 GFYKG+ +++ A + F+V E + F++ Sbjct: 276 GGFYKGIAPNLIRVTPACCITFVVYENVSHFLL 308 Score = 55.1 bits (131), Expect = 2e-07 Identities = 38/146 (26%), Positives = 71/146 (48%), Gaps = 3/146 (2%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPY--GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYET 477 ++K R A D + RP G + + +++ G+ G ++G+ P + + + +Y Sbjct: 45 LVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGVTPN---IWGAGLSWGLYFF 101 Query: 476 LSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA 297 ++S ++ R + + A E + A A +T PL V K+RL + + N+ Sbjct: 102 FYNAIKSYKTEGR--AERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSP 159 Query: 296 SR-YTGTLDAILKMIRYEGLHGFYKG 222 R Y G D ++K+ +YEG+ G YKG Sbjct: 160 HRQYKGMFDTLVKIYKYEGVRGLYKG 185 Score = 40.0 bits (92), Expect = 0.007 Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Frame = -3 Query: 632 AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQS 456 A+L + G I I + +R+ G+ GF+KG+ P LI V I F++YE +S L Sbjct: 250 ARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLD 309 Query: 455 KRSGKR 438 R ++ Sbjct: 310 LREKRK 315
>PM47B_CANBO (Q00319) Peroxisomal membrane protein PMP47B| Length = 419 Score = 87.8 bits (216), Expect = 3e-17 Identities = 55/187 (29%), Positives = 88/187 (47%), Gaps = 39/187 (20%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 417 TI+AI + + G + G++P L +V NP IQ+ I+E L + + K+N+T Sbjct: 187 TIEAIIYILKNEGWQKLFTGIVPALFLVLNPIIQYTIFEQLKSFIV------KIKKRNVT 240 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR------------------ 291 ++ LLGA KL AT++TYP + ++SR+ K N S Sbjct: 241 PVDALLLGAFGKLIATIITYPYITLRSRMHVKSMTENNEDSEKERTDSVQSLPEDGSDED 300 Query: 290 ------YTGTLDAIL---------------KMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 Y T++ I+ KM + EG+ FY+G+ K++QS+ A+ LF Sbjct: 301 NSKENPYAETINKIISKLPSPIVSMFIIGYKMYKEEGVSSFYRGLSVKLLQSILNAAFLF 360 Query: 173 MVKEELV 153 KEEL+ Sbjct: 361 YFKEELL 367
>MFTC_MOUSE (Q8BMG8) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 316 Score = 87.4 bits (215), Expect = 4e-17 Identities = 51/160 (31%), Positives = 83/160 (51%), Gaps = 1/160 (0%) Frame = -3 Query: 620 SEKPRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSG 444 S R Y G A+ ++Y+ G+ G +KG +P L + ++QFM YE L +L+ + Sbjct: 157 SPSQRQYKGMFDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELL--KLKYNKHI 214 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 R P+ ++ E + A++K+ A TYP VV++RLQ + Y G D I Sbjct: 215 NRLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARLQDQHV-------SYGGVTDVIT 267 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 K R EG+ GFYKG+ +++ A + F+V E + F+ Sbjct: 268 KTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307 Score = 39.7 bits (91), Expect = 0.009 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Frame = -3 Query: 632 AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQS 456 A+L + G I + +R+ GI GF+KG+ P LI V I F++YE +S L Sbjct: 250 ARLQDQHVSYGGVTDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFLYD 309 Query: 455 KRSGK 441 R K Sbjct: 310 LREKK 314
>PM47A_CANBO (P21245) Peroxisomal membrane protein PMP47A| Length = 423 Score = 84.7 bits (208), Expect = 2e-16 Identities = 57/191 (29%), Positives = 89/191 (46%), Gaps = 43/191 (22%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 417 TI+AI + + G + G++P L +V NP IQ+ I+E L + + K+NIT Sbjct: 187 TIEAIIYILKNEGWQKLFTGIVPALFLVLNPIIQYTIFEQLKSFIV------KIKKRNIT 240 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ--EIGRN-------------------- 303 ++ LLGA KL AT++TYP + ++SR+ K EI + Sbjct: 241 PVDALLLGAFGKLIATIITYPYITLRSRMHVKSMTEISEDVEKERTDSVQSLPEDGSDED 300 Query: 302 ------AASRYTGTLDAILK---------------MIRYEGLHGFYKGMGTKIVQSVFAA 186 A S Y T+ I+ M + EG+ FY+G+ K++QS+ A Sbjct: 301 NLKENSAKSPYAETITKIISKLPSPIVSMFTLGYGMYKEEGVSSFYRGLSVKLLQSILNA 360 Query: 185 SVLFMVKEELV 153 + LF KEEL+ Sbjct: 361 AFLFYFKEELL 371
>ANT1_YEAST (Q06497) Peroxisomal adenine nucleotide transporter 1| Length = 328 Score = 81.6 bits (200), Expect = 2e-15 Identities = 50/167 (29%), Positives = 92/167 (55%), Gaps = 2/167 (1%) Frame = -3 Query: 584 IREVYRESG--ISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM 411 I+++YRE+ I+ FWKGL L + NPSI + ++ L + S +++A+ Sbjct: 167 IKDIYRENNGDITAFWKGLRTGLALTINPSITYASFQRLKEVFFHDHSNDA---GSLSAV 223 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + F+LG ++K+ +T+VT PL+V K+ LQ+ A S++T +A+L + + EGL Sbjct: 224 QNFILGVLSKMISTLVTQPLIVAKAMLQS-------AGSKFTTFQEALLYLYKNEGLKSL 276 Query: 230 YKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSRTLLLTRSNKR 90 +KG+ ++ + V +LF + EL K + L+ + L + +R Sbjct: 277 WKGVLPQLTKGVIVQGLLFAFRGELTKSLKRLIFLYSSFFLKHNGQR 323 Score = 36.2 bits (82), Expect = 0.094 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS---------RYTGTLDAILK 261 +E L GA+A A + YPL + K+ +Q++ + S RY +D ++ Sbjct: 4 LESALTGAVASAMANIAVYPLDLSKTIIQSQVSPSSSEDSNEGKVLPNRRYKNVVDCMIN 63 Query: 260 MIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 + + +G+ G Y+GM V + V F Sbjct: 64 IFKEKGILGLYQGMTVTTVATFVQNFVYF 92
>ANT1_ASHGO (Q75A82) Peroxisomal adenine nucleotide transporter 1| Length = 340 Score = 75.5 bits (184), Expect = 1e-13 Identities = 51/167 (30%), Positives = 85/167 (50%), Gaps = 3/167 (1%) Frame = -3 Query: 581 REVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM--- 411 REV+ E+G GFW GL +L++ NPSI + YE L + L + + + Sbjct: 180 REVHAENGWRGFWAGLKVSLVLTVNPSITYATYERLREALFPTPAAASHLVDSAALLSPG 239 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + F++G ++K+ +TV+T PL++ K+ LQ + S + + + EG Sbjct: 240 QNFVMGVLSKIVSTVLTQPLIIAKASLQ-------RSGSCFQDFHQVLHHLYSTEGPLSL 292 Query: 230 YKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSRTLLLTRSNKR 90 +KG+G +I + V +LFM K EL K + L+ L L RS++R Sbjct: 293 WKGLGPQITKGVLVQGLLFMFKGELTKMLRKLMF---YLALLRSSRR 336 Score = 36.6 bits (83), Expect = 0.072 Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 28/99 (28%) Frame = -3 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQ---------AKQEIGRN------------- 303 + E ++GA A A + YPL + K+ +Q A +E G Sbjct: 2 SFENAVIGATASSLANIAVYPLDLAKTLVQTQLKDEFVEAGEEAGEERAGSRRQNRIKPI 61 Query: 302 ------AASRYTGTLDAILKMIRYEGLHGFYKGMGTKIV 204 AA +Y G LDA+ ++ EG+ G Y+G+G+ V Sbjct: 62 ALRSPQAAEQYKGALDALQRIYGAEGVAGLYRGLGSSTV 100
>YEA6_YEAST (P39953) Putative mitochondrial carrier YEL006W| Length = 335 Score = 73.9 bits (180), Expect = 4e-13 Identities = 47/153 (30%), Positives = 80/153 (52%), Gaps = 1/153 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRL-QSKRSGKRFPKKN 423 GTI R++ ++ G + GL+P L+ + N +IQF +YE L R S+ + + Sbjct: 181 GTIDTFRKIIQQEGAKALYAGLVPALLGMLNVAIQFPLYENLKIRFGYSESTDVSTDVTS 240 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 ++ L ++K+ A+ VTYP ++++R+Q K ++ N R+ L I R EG Sbjct: 241 SNFQKLILASMLSKMVASTVTYPHEILRTRMQLKSDL-PNTVQRH--LLPLIKITYRQEG 297 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 GFY G T +V++V AA V + E K++ Sbjct: 298 FAGFYSGFATNLVRTVPAAVVTLVSFEYSKKYL 330 Score = 53.5 bits (127), Expect = 6e-07 Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 3/122 (2%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI--TAMEV 405 ++++ G +G +KGL PT++ + I F +Y+ K S FP A Sbjct: 91 IFKDEGAAGLYKGLQPTVLGYIPTLMIYFSVYDFCRKY-----SVDIFPHSPFLSNASSA 145 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 GAI+ TV T P+ VVK+RL + IG+ + + Y GT+D K+I+ EG Y Sbjct: 146 ITAGAIS----TVATNPIWVVKTRLMLQTGIGKYS-THYKGTIDTFRKIIQQEGAKALYA 200 Query: 224 GM 219 G+ Sbjct: 201 GL 202 Score = 33.9 bits (76), Expect = 0.47 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 1/98 (1%) Frame = -3 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ-EIGRNAASRYTGTLDAILKMI 255 KKN + GA++ + ++ P V K+RLQA+ + + + Y G + Sbjct: 33 KKNADPRVAAISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFATIF 92 Query: 254 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 + EG G YKG+ ++ + + F V + K+ + Sbjct: 93 KDEGAAGLYKGLQPTVLGYIPTLMIYFSVYDFCRKYSV 130
>TXTP_BOVIN (P79110) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 73.2 bits (178), Expect = 7e-13 Identities = 46/160 (28%), Positives = 81/160 (50%), Gaps = 1/160 (0%) Frame = -3 Query: 620 SEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSG 444 S P+ G +RE+ RE G+ G ++GL T++ N I+F + +L + Sbjct: 156 SASPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQGIRFFVMTSLRNWYRGDN-- 213 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 P K + + + GAIA + PL V+K+R+Q + A +Y TLD L Sbjct: 214 ---PNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLE------AHKYRNTLDCGL 264 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 +++R EGL FYKG ++ + +++F++ +E+VK + Sbjct: 265 QILRNEGLKAFYKGTVPRLGRVCLDVAIVFIIYDEVVKLL 304 Score = 40.0 bits (92), Expect = 0.007 Identities = 24/79 (30%), Positives = 41/79 (51%) Frame = -3 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + L G +A +T+P VK++LQ + R+ RY G D + + +R GL G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDE---RSHPPRYRGIGDCVRQTVRSHGLLGL 83 Query: 230 YKGMGTKIVQSVFAASVLF 174 Y+G+ + + S+ A+V F Sbjct: 84 YRGLSSLLYGSIPKAAVRF 102
>BT1_MAIZE (P29518) Protein brittle-1, chloroplast precursor| Length = 436 Score = 71.2 bits (173), Expect = 3e-12 Identities = 48/150 (32%), Positives = 80/150 (53%), Gaps = 1/150 (0%) Frame = -3 Query: 587 AIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM 411 A ++ R+ G S ++GL P+LI +V + F YETL KRL + +G+R P ++ + Sbjct: 270 AFVKILRDEGPSELYRGLTPSLIGVVPYAACNFYAYETL-KRLYRRATGRR-PGADVGPV 327 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 L+G+ A A+ T+PL V + ++Q GR Y L AI +++ EG G Sbjct: 328 ATLLIGSAAGAIASSATFPLEVARKQMQVGAVGGRQV---YQNVLHAIYCILKKEGAGGL 384 Query: 230 YKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 Y+G+G ++ + AA + FM E K ++ Sbjct: 385 YRGLGPSCIKLMPAAGIAFMCYEACKKILV 414 Score = 47.4 bits (111), Expect = 4e-05 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 1/141 (0%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 399 + + G +G ++G ++ V + +I+ Y+T K L K G PK I + Sbjct: 179 IMQNEGWTGLFRGNAVNVLRVAPSKAIEHFTYDTAKKFLTPK--GDEPPK--IPIPTPLV 234 Query: 398 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 219 GA+A +T+ TYP+ ++K+R+ ++++ Y A +K++R EG Y+G+ Sbjct: 235 AGALAGFASTLCTYPMELIKTRVTIEKDV-------YDNVAHAFVKILRDEGPSELYRGL 287 Query: 218 GTKIVQSVFAASVLFMVKEEL 156 ++ V A+ F E L Sbjct: 288 TPSLIGVVPYAACNFYAYETL 308
>YIA6_YEAST (P40556) Putative mitochondrial carrier YIL006W| Length = 373 Score = 70.9 bits (172), Expect = 3e-12 Identities = 42/147 (28%), Positives = 77/147 (52%), Gaps = 1/147 (0%) Frame = -3 Query: 617 EKPRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGK 441 E P Y GT A R+++ + G + GL+P+L+ + + +I F IYE L R + Sbjct: 212 EHPTHYKGTFDAFRKLFYQEGFKALYAGLVPSLLGLFHVAIHFPIYEDLKVRFHC--YSR 269 Query: 440 RFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILK 261 +I + + +++K+ A+ VTYP ++++R+Q K +I + R + A Sbjct: 270 ENNTNSINLQRLIMASSVSKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYA 329 Query: 260 MIRYEGLHGFYKGMGTKIVQSVFAASV 180 EGL GFY G T +V+++ A+++ Sbjct: 330 Q---EGLKGFYSGFTTNLVRTIPASAI 353 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/156 (28%), Positives = 75/156 (48%), Gaps = 2/156 (1%) Frame = -3 Query: 617 EKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRLQSKRSG 444 E P G + + + R+ G G +KGL+P +++ P+ I F +YE K Sbjct: 115 ENPYYRGIMGTLSTIVRDEGPRGLYKGLVP-IVLGYFPTWMIYFSVYEFSKKFFHG---- 169 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 FP+ + A + A A +T +T P+ VVK+RL + +G + + Y GT DA Sbjct: 170 -IFPQFDFVAQSCAAITAGA--ASTTLTNPIWVVKTRLMLQSNLGEH-PTHYKGTFDAFR 225 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 K+ EG Y G+ ++ +F ++ F + E+L Sbjct: 226 KLFYQEGFKALYAGLVPSLL-GLFHVAIHFPIYEDL 260 Score = 37.7 bits (86), Expect = 0.032 Identities = 28/84 (33%), Positives = 39/84 (46%) Frame = -3 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 222 L GA A + V PL V K+RLQA+ R Y G + + ++R EG G YKG Sbjct: 82 LSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPRGLYKG 141 Query: 221 MGTKIVQSVFAASVLFMVKEELVK 150 + IV F +++ E K Sbjct: 142 L-VPIVLGYFPTWMIYFSVYEFSK 164
>TXTP_RAT (P32089) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 70.1 bits (170), Expect = 6e-12 Identities = 43/160 (26%), Positives = 81/160 (50%), Gaps = 1/160 (0%) Frame = -3 Query: 620 SEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSG 444 S P+ G +RE+ RE G+ G ++GL T++ N +I+F + +L Q Sbjct: 156 SSNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDN-- 213 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 P K + + + GA+A + PL V+K+R+Q + A +Y TLD + Sbjct: 214 ---PNKPMNPLITGVFGAVAGAASVFGNTPLDVIKTRMQGLE------AHKYRNTLDCGV 264 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 ++++ EG FYKG ++ + +++F++ +E+VK + Sbjct: 265 QILKNEGPKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLL 304 Score = 38.1 bits (87), Expect = 0.025 Identities = 25/85 (29%), Positives = 43/85 (50%) Frame = -3 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + L G +A +T+P VK++LQ + R RY G D + + +R G+ G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDE---RANPPRYRGIGDCVRQTVRSHGVLGL 83 Query: 230 YKGMGTKIVQSVFAASVLFMVKEEL 156 Y+G+ + + S+ A+V F + E L Sbjct: 84 YRGLSSLLYGSIPKAAVRFGMFEFL 108
>TXTP_HUMAN (P53007) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 70.1 bits (170), Expect = 6e-12 Identities = 44/160 (27%), Positives = 81/160 (50%), Gaps = 1/160 (0%) Frame = -3 Query: 620 SEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSG 444 S P+ G +RE+ RE G+ G ++GL T++ N +I+F + +L + Sbjct: 156 SPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDN-- 213 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 P K + + + GAIA + PL V+K+R+Q + A +Y T D L Sbjct: 214 ---PNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLE------AHKYRNTWDCGL 264 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 ++++ EGL FYKG ++ + +++F++ +E+VK + Sbjct: 265 QILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLL 304 Score = 39.3 bits (90), Expect = 0.011 Identities = 25/85 (29%), Positives = 44/85 (51%) Frame = -3 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + L G +A +T+P VK++LQ + R+ RY G D + + +R G+ G Sbjct: 27 KAILAGGLAGGIEICITFPTEYVKTQLQLDE---RSHPPRYRGIGDCVRQTVRSHGVLGL 83 Query: 230 YKGMGTKIVQSVFAASVLFMVKEEL 156 Y+G+ + + S+ A+V F + E L Sbjct: 84 YRGLSSLLYGSIPKAAVRFGMFEFL 108
>FLX1_YEAST (P40464) Mitochondrial FAD carrier protein FLX1| Length = 311 Score = 68.9 bits (167), Expect = 1e-11 Identities = 42/167 (25%), Positives = 85/167 (50%), Gaps = 2/167 (1%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTI-QAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETL 474 ++K R+ Y ++ ++++ R G G WKGL+P L V ++ F +Y+TL Sbjct: 148 VIKTRIMSTSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGLVPALFGVSQGALYFAVYDTL 207 Query: 473 SKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS 294 +R + +R + ++T +E + ++ K+ + + YP ++KS LQ+ + A+ Sbjct: 208 KQR-KLRRKRENGLDIHLTNLETIEITSLGKMVSVTLVYPFQLLKSNLQSFR------AN 260 Query: 293 RYTGTLDAILKM-IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 L ++K+ I +G G YKG+ +V+++ + + F V E L Sbjct: 261 EQKFRLFPLIKLIIANDGFVGLYKGLSANLVRAIPSTCITFCVYENL 307 Score = 43.1 bits (100), Expect = 8e-04 Identities = 45/207 (21%), Positives = 90/207 (43%), Gaps = 15/207 (7%) Frame = -3 Query: 671 VNSMDAHILKDRLAKLDSEKPRPYGTIQAIREVYRESGISG------FWKGLIPTLI-MV 513 V+ +D ++ +L+ ++K YG I+E+ R S SG ++GL L Sbjct: 27 VHPLDLLKVRLQLSATSAQKAH-YGPFMVIKEIIRSSANSGRSVTNELYRGLSINLFGNA 85 Query: 512 CNPSIQF--------MIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTY 357 + F +IY++++K +++ G K + ++ GA + L ++T Sbjct: 86 IAWGVYFGLYGVTKELIYKSVAKPGETQLKGVGNDHK-MNSLIYLSAGASSGLMTAILTN 144 Query: 356 PLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVL 177 P+ V+K+R+ + + A YT + + +++R +G G +KG+ L Sbjct: 145 PIWVIKTRIMS---TSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGL----------VPAL 191 Query: 176 FMVKEELVKFVILLVARSRTLLLTRSN 96 F V + + F + + R L R N Sbjct: 192 FGVSQGALYFAVYDTLKQRKLRRKREN 218
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 68.9 bits (167), Expect = 1e-11 Identities = 48/164 (29%), Positives = 78/164 (47%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSK 468 L+ + L + P GTI R+ GI+G ++G+ +I V L K Sbjct: 38 LQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGK 97 Query: 467 RLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY 288 RLQ K P+ +T ++F G ++ + T + P +K LQ + G+N +Y Sbjct: 98 RLQQKS-----PEDELTYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGKN---KY 149 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 +GTLD K+ + G+ GFYKG +++ V A+ + FM E L Sbjct: 150 SGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWL 193 Score = 52.0 bits (123), Expect = 2e-06 Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 2/152 (1%) Frame = -3 Query: 620 SEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSG 444 S K + GT+ +++Y+E GI GF+KG TL+ V + FM YE L + G Sbjct: 144 SGKNKYSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQ--G 201 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAI 267 K +++ V + G + VV P V+KSR Q +Y G D + Sbjct: 202 KSV--HDLSVPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPP------GKYPNGFRDVL 253 Query: 266 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFM 171 ++IR EG+ YKG ++++ A + F+ Sbjct: 254 RELIREEGVTSLYKGFNAVMIRAFPANAACFL 285 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/75 (32%), Positives = 36/75 (48%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 K I+ ++ L G + V +PL VK RLQ + Y+GT+D K + Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFR 65 Query: 248 EGLHGFYKGMGTKIV 204 EG+ G Y+GM I+ Sbjct: 66 EGITGLYRGMAAPII 80
>MCATL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 303 Score = 65.9 bits (159), Expect = 1e-10 Identities = 45/154 (29%), Positives = 80/154 (51%), Gaps = 3/154 (1%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYE 480 + K RL D+ R Y G++ + ++Y G+ G +G++ TL+ PS + F+ Y+ Sbjct: 115 LAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRE-TPSFGVYFLTYD 173 Query: 479 TLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNA 300 L++ L + P + ++ L G + + + + TYP+ VVKSRLQA G Sbjct: 174 ALTRALGCE------PGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQAD---GLRG 224 Query: 299 ASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQS 198 A RY G LD + + R EG F +G+ + ++++ Sbjct: 225 APRYRGILDCVHQSYRAEGWRVFTRGLASTLLRA 258 Score = 54.7 bits (130), Expect = 3e-07 Identities = 44/166 (26%), Positives = 80/166 (48%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSK 468 +K RL EKP+ GT+ + + ++ + G +KGL L+ + I +++ Sbjct: 25 VKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLT--FINALVFGVQGN 82 Query: 467 RLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY 288 L++ G P + FL GA A V+ P+ + K+RLQ Q+ G A Y Sbjct: 83 TLRAL--GHDSP------LNQFLAGAAAGAIQCVICCPMELAKTRLQL-QDAG--PARTY 131 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 G+LD + ++ +EGL G +GM + +++ + V F+ + L + Sbjct: 132 KGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTR 177 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/80 (30%), Positives = 40/80 (50%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 FL G + +V +P VK RLQ + +Y GTL +I+ E + G YK Sbjct: 5 FLAGCAGGVAGVLVGHPFDTVKVRLQVQSV----EKPQYRGTLHCFKSIIKQESVLGLYK 60 Query: 224 GMGTKIVQSVFAASVLFMVK 165 G+G+ ++ F +++F V+ Sbjct: 61 GLGSPLMGLTFINALVFGVQ 80
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (mCAC) (Solute carrier family 25 member 20) Length = 301 Score = 64.7 bits (156), Expect = 2e-10 Identities = 45/164 (27%), Positives = 77/164 (46%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSK 468 L+ + L + P GT+ R+ GI+G ++G+ +I V L K Sbjct: 38 LQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGK 97 Query: 467 RLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY 288 +LQ K P+ ++ ++F G ++ + T + P +K LQ + G N +Y Sbjct: 98 KLQQKS-----PEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGEN---KY 149 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 +GTLD K+ + G+ GFYKG +++ V A+ + FM E L Sbjct: 150 SGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWL 193 Score = 56.2 bits (134), Expect = 9e-08 Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 GT+ +++Y+E GI GF+KG + TL+ V + FM YE L + GK + Sbjct: 151 GTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPE--GKSV--SD 206 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAILKMIRYE 246 ++ + + G A + V P V+KSR Q +Y G D + ++IR E Sbjct: 207 LSVPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPP------GKYPNGFRDVLRELIREE 260 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G+ YKG ++++ A + F+ E +KF+ Sbjct: 261 GVTSLYKGFNAVMIRAFPANAACFLGFEIAMKFL 294 Score = 43.9 bits (102), Expect = 5e-04 Identities = 25/75 (33%), Positives = 35/75 (46%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 K I+ + L G + V +PL VK RLQ + Y+GTLD K + Sbjct: 6 KPISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMR 65 Query: 248 EGLHGFYKGMGTKIV 204 EG+ G Y+GM I+ Sbjct: 66 EGITGLYRGMAAPII 80
>DNC_MACFA (Q5IS35) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 63.9 bits (154), Expect = 4e-10 Identities = 47/167 (28%), Positives = 84/167 (50%), Gaps = 8/167 (4%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQ-AIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYET 477 +L+ R A +P+ Y T++ A+ +YR G F+KGL PTLI + +QF Y + Sbjct: 141 VLRTRFAA--QGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198 Query: 476 LSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQ------AKQE 315 L + + +N+ + L G+ A + + +TYPL + K RLQ A+ Sbjct: 199 LKHLYKWAMPAEGKKNENLQNL---LCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAA 255 Query: 314 IGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 G+ RY G +D ++++ EG GF+KG+ ++++ + +F Sbjct: 256 FGQ--VRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/97 (27%), Positives = 50/97 (51%), Gaps = 2/97 (2%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE--IGRNAASRYTGTLDAILKMI 255 +N T ++V + G+++ L + P V+K R Q + E R+ ++Y G A +++ Sbjct: 11 RNNTKLQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQIL 70 Query: 254 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 + EGL F+KG + S+ +V F+ E L + V Sbjct: 71 QEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLTELV 107
>DNC_HUMAN (Q9HC21) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) (Mitochondrial uncoupling protein 1) Length = 320 Score = 63.5 bits (153), Expect = 5e-10 Identities = 48/171 (28%), Positives = 85/171 (49%), Gaps = 8/171 (4%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQ-AIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYET 477 +L+ R A +P+ Y T++ A+ +YR G F+KGL PTLI + +QF Y + Sbjct: 141 VLRTRFAA--QGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198 Query: 476 LSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQ------AKQE 315 L + + +N+ + L G+ A + + +TYPL + K RLQ A+ Sbjct: 199 LKHLYKWAIPAEGKKNENLQNL---LCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAA 255 Query: 314 IGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 G+ RY G +D ++++ EG GF+KG+ ++++ + +F E Sbjct: 256 FGQ--VRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>DNC_PONPY (Q5NVC1) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 62.8 bits (151), Expect = 9e-10 Identities = 47/167 (28%), Positives = 83/167 (49%), Gaps = 8/167 (4%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTI-QAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYET 477 +L+ R A +P+ Y T+ A+ +YR G F+KGL PTLI + +QF Y + Sbjct: 141 VLRTRFAA--QGEPKVYNTLCHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198 Query: 476 LSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQ------AKQE 315 L + + +N+ + L G+ A + + +TYPL + K RLQ A+ Sbjct: 199 LKHLYKWAIPAEGKKNENLQNL---LCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAA 255 Query: 314 IGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 G+ RY G +D ++++ EG GF+KG+ ++++ + +F Sbjct: 256 FGQ--VRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMF 300
>ADT_KLULA (P49382) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 305 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 1/144 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + ++ G++G ++G +P+++ +V + F +Y++L L + F Sbjct: 159 GLVDVYKKTLASDGVAGLYRGFLPSVVGIVVYRGLYFGLYDSLKPLLLTGSLENSF---- 214 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + FLLG GA+ +YPL V+ R+ A +Y G DA K++ EG Sbjct: 215 ---LASFLLGWAVTTGASTASYPLDTVRRRMMMTS----GQAVKYDGAFDAFRKIVAAEG 267 Query: 242 LHGFYKGMGTKIVQSVFAASVLFM 171 + +KG G I++ V A V+ M Sbjct: 268 IKSLFKGCGANILRGVAGAGVISM 291 Score = 32.7 bits (73), Expect = 1.0 Identities = 18/85 (21%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILKMIRYEGLHGF 231 FL+G ++ + P+ VK +Q + E+ + + RYTG ++ + EG+ F Sbjct: 14 FLMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKQGSLDRRYTGIVECFKRTAADEGVASF 73 Query: 230 YKGMGTKIVQSVFAASVLFMVKEEL 156 ++G +++ ++ F K+++ Sbjct: 74 WRGNTANVIRYFPTQALNFAFKDKI 98
>ADT2_YEAST (P18239) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 318 Score = 62.8 bits (151), Expect = 9e-10 Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 1/144 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G I ++ + G++G ++G +P+++ +V + F +Y++L L + F Sbjct: 172 GLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSF---- 227 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + FLLG + GA+ +YPL V+ R+ A +Y G D + K++ EG Sbjct: 228 ---LASFLLGWVVTTGASTCSYPLDTVRRRMMMTS----GQAVKYDGAFDCLRKIVAAEG 280 Query: 242 LHGFYKGMGTKIVQSVFAASVLFM 171 + +KG G I++ V A V+ M Sbjct: 281 VGSLFKGCGANILRGVAGAGVISM 304 Score = 37.0 bits (84), Expect = 0.055 Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Frame = -3 Query: 434 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILK 261 PKK + FL+G ++ A P+ VK +Q + E+ + +Y G LD + Sbjct: 17 PKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKR 76 Query: 260 MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 EG+ F++G +++ ++ F K+++ Sbjct: 77 TATQEGVISFWRGNTANVIRYFPTQALNFAFKDKI 111
>TXTP_CAEEL (P34519) Putative tricarboxylate transport protein, mitochondrial| precursor (Citrate transport protein) (CTP) Length = 312 Score = 62.0 bits (149), Expect = 2e-09 Identities = 41/158 (25%), Positives = 78/158 (49%), Gaps = 1/158 (0%) Frame = -3 Query: 614 KPRPYGTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSGKR 438 +P+ G + + + + G+ G +KG+ T+ N +I+F + ETL R G Sbjct: 158 QPKYKGFVHGVGCIVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETLKDWY---RGGDN 214 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM 258 + I+ V L+GA+A + P+ VVK+R+Q + A +Y TLD +++ Sbjct: 215 --TQPISKPIVGLMGAVAGAASVYGNTPIDVVKTRMQGLE------AKKYKNTLDCAMQI 266 Query: 257 IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 + EG FYKG ++ + + FM+ + +++F+ Sbjct: 267 WKKEGFFAFYKGTVPRLSRVCLDVGITFMIYDSIIEFL 304 Score = 40.8 bits (94), Expect = 0.004 Identities = 38/157 (24%), Positives = 66/157 (42%), Gaps = 2/157 (1%) Frame = -3 Query: 620 SEKPRPYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSG 444 S P+ G I +++ G G ++GL L + S +F +E L + +R Sbjct: 59 SATPKFRGPIDCVKQTVNGHGFFGLYRGLSVLLYGSIPKSSFRFGTFEYLKSQAADERG- 117 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTY-PLLVVKSRLQAKQEIGRNAASRYTGTLDAI 267 N++ + L G A L V P+ VK + Q + A +Y G + + Sbjct: 118 ------NLSPVMRLLCGLGAGLSEAVFAVTPMETVKVKFIHDQGL---AQPKYKGFVHGV 168 Query: 266 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 +++ EGL G YKG+ + + ++ F V E L Sbjct: 169 GCIVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETL 205
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrier-like protein| (Protein A BOUT DE SOUFFLE) (Carnitine/acylcarnitine translocase-like protein) (CAC-like protein) Length = 300 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/148 (31%), Positives = 67/148 (45%), Gaps = 2/148 (1%) Frame = -3 Query: 599 GTIQAIREVYR-ESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKK 426 G + R V R E G G +KGL PT V + F YE + L + Sbjct: 155 GPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAGGSDTSSLGQG 214 Query: 425 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 ++ + G +A + YP VVKS LQ + RYTG++DA K+++ E Sbjct: 215 SL-----IMAGGVAGASFWGIVYPTDVVKSVLQ----VDDYKNPRYTGSMDAFRKILKSE 265 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKE 162 G+ G YKG G + +SV A + F+ E Sbjct: 266 GVKGLYKGFGPAMARSVPANAACFLAYE 293 Score = 50.1 bits (118), Expect = 6e-06 Identities = 25/80 (31%), Positives = 40/80 (50%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 G + VV +P +K +LQ++ RYTG +DA+ + + EG G YKGMG Sbjct: 11 GTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMG 70 Query: 215 TKIVQSVFAASVLFMVKEEL 156 + +VLF V+ ++ Sbjct: 71 APLATVAAFNAVLFTVRGQM 90 Score = 31.6 bits (70), Expect = 2.3 Identities = 13/43 (30%), Positives = 24/43 (55%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTL 522 ++K L D + PR G++ A R++ + G+ G +KG P + Sbjct: 236 VVKSVLQVDDYKNPRYTGSMDAFRKILKSEGVKGLYKGFGPAM 278
>ADT3_YEAST (P18238) ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine| nucleotide translocator 3) (ANT 3) Length = 307 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/144 (25%), Positives = 71/144 (49%), Gaps = 1/144 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G ++ + GI+G ++G +P+++ +V + F ++++L + + F Sbjct: 161 GLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSF---- 216 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + FLLG + GA+ +YPL V+ R+ A +Y G +D + K++ EG Sbjct: 217 ---LASFLLGWVVTTGASTCSYPLDTVRRRMMMTS----GQAVKYNGAIDCLKKIVASEG 269 Query: 242 LHGFYKGMGTKIVQSVFAASVLFM 171 + +KG G I++SV A V+ M Sbjct: 270 VGSLFKGCGANILRSVAGAGVISM 293 Score = 35.0 bits (79), Expect = 0.21 Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILKMIRYEGLHGF 231 FL+G ++ A P+ VK +Q + E+ + +Y+G +D + + EGL F Sbjct: 16 FLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISF 75 Query: 230 YKGMGTKIVQSVFAASVLFMVKEEL 156 ++G +++ ++ F K+++ Sbjct: 76 WRGNTANVIRYFPTQALNFAFKDKI 100
>MCATL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 306 Score = 60.8 bits (146), Expect = 4e-09 Identities = 45/167 (26%), Positives = 85/167 (50%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLS 471 I+K RL +EKP+ GT+ + + ++ + G +KGL L+ + I +++ Sbjct: 24 IVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLT--FINALVFGVQG 81 Query: 470 KRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR 291 L++ G+ P + FL GA A V+ P+ + K+RLQ Q +G A Sbjct: 82 NTLRAL--GQDSP------LNQFLAGAAAGAIQCVICCPMELAKTRLQL-QAVG--PART 130 Query: 290 YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 Y G+LD ++++ R+EGL G +GM + +++ + V F+ + + + Sbjct: 131 YKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVMTR 177 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/136 (25%), Positives = 72/136 (52%), Gaps = 2/136 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETLSKRLQSKRSGKRFPKK 426 G++ + ++YR G+ G +G++ TL+ PS + F+ Y+ +++ + + P Sbjct: 133 GSLDCLVQIYRHEGLRGINRGMVSTLLRE-TPSFGVYFLTYDVMTRAMGCE------PGD 185 Query: 425 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 + ++ L G + + + + TYP+ VVKSRLQA G RY G +D + + + E Sbjct: 186 RLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQAD---GLQGTPRYRGIVDCMRQSYQAE 242 Query: 245 GLHGFYKGMGTKIVQS 198 G F +G+ + ++++ Sbjct: 243 GWQVFTRGLASTLLRA 258 Score = 44.3 bits (103), Expect = 3e-04 Identities = 24/80 (30%), Positives = 41/80 (51%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 FL G + +V +P +VK RLQ + +Y GTL +I+ E + G YK Sbjct: 5 FLAGCAGGVAGVIVGHPFDIVKVRLQVQS----TEKPQYRGTLHCFQSIIKQESVLGLYK 60 Query: 224 GMGTKIVQSVFAASVLFMVK 165 G+G+ ++ F +++F V+ Sbjct: 61 GLGSPLMGLTFINALVFGVQ 80
>ADT1_YEAST (P04710) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 309 Score = 60.8 bits (146), Expect = 4e-09 Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 2/153 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + ++ + G+ G ++G +P+++ ++ + F +Y++ L + F Sbjct: 163 GLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSF---- 218 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + FLLG + +GA+ +YPL V+ R+ +Y G LD + K+++ EG Sbjct: 219 ---VASFLLGWVITMGASTASYPLDTVRRRMMMTS----GQTIKYDGALDCLRKIVQKEG 271 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKE-ELVKF 147 + +KG G I + V AA V+ + + +L+ F Sbjct: 272 AYSLFKGCGANIFRGVAAAGVISLYDQLQLIMF 304 Score = 38.1 bits (87), Expect = 0.025 Identities = 35/159 (22%), Positives = 63/159 (39%), Gaps = 2/159 (1%) Frame = -3 Query: 644 KDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSK 468 ++ + K S R G + + GI FW+G ++ ++ F + + Sbjct: 44 QEEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKS 103 Query: 467 RLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR- 291 L R + K A +F GA L V Y L ++RL A ++ + R Sbjct: 104 LLSYDRERDGYAKW--FAGNLFSGGAAGGLSLLFV-YSLDYARTRLAADARGSKSTSQRQ 160 Query: 290 YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 + G LD K ++ +GL G Y+G ++ + + F Sbjct: 161 FNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYF 199 Score = 35.4 bits (80), Expect = 0.16 Identities = 20/85 (23%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA--SRYTGTLDAILKMIRYEGLHGF 231 FL+G ++ A P+ VK +Q ++E+ + + +RY G LD + +EG+ F Sbjct: 17 FLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSF 76 Query: 230 YKGMGTKIVQSVFAASVLFMVKEEL 156 ++G +++ ++ F K+++ Sbjct: 77 WRGNTANVLRYFPTQALNFAFKDKI 101
>CMC2_CAEEL (Q20799) Probable calcium-binding mitochondrial carrier F55A11.4| Length = 588 Score = 60.8 bits (146), Expect = 4e-09 Identities = 51/173 (29%), Positives = 86/173 (49%), Gaps = 8/173 (4%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETL 474 ++K RLA L G I ++Y + GI F+KG +P LI ++ I IYETL Sbjct: 367 VMKTRLA-LRKTGQLDRGIIHFAHKMYTKEGIRCFYKGYLPNLIGIIPYAGIDLAIYETL 425 Query: 473 SKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGAT---VVTYPLLVVKSRLQAKQEIGRN 303 KR+ R+ + N + V L A +T + +YP +V++RLQA Sbjct: 426 ------KRTYVRYYETNSSEPGVLALLACGTCSSTCGQLSSYPFALVRTRLQAL------ 473 Query: 302 AASRYTGTLDAILKMIRY----EGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 + +RY+ D + +Y EG+ GFY+G+ ++ + A S+ ++V E++ Sbjct: 474 SITRYSPQPDTMFGQFKYILQNEGVTGFYRGITPNFLKVIPAVSISYVVYEKV 526
>DNC_MOUSE (Q9DAM5) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 318 Score = 60.8 bits (146), Expect = 4e-09 Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 12/171 (7%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTI-QAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYET 477 +L+ RLA +P+ Y + +AIR +Y+ G F+KGL PT+I + +QF Y + Sbjct: 141 VLRTRLAA--QGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRS 198 Query: 476 LSKRLQ------SKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ- 318 L + K++G KN+ L G + + + TYPL ++K RLQ Sbjct: 199 LKRAYDWLIPPDGKQTGNL---KNL------LCGCGSGVISKTFTYPLDLIKKRLQVGGF 249 Query: 317 EIGRNAASR---YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 E R+A + Y G LD ++++ EG GF+KG+ ++++ + +F Sbjct: 250 EHARSAFGQVRSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMKAALSTGFMF 300 Score = 36.6 bits (83), Expect = 0.072 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 2/92 (2%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE--IGRNAASRYTGTLDAILKMIRYEGL 240 +EV + G+++ + PL V+K R Q + E + ++Y G A ++++ EG Sbjct: 16 LEVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGP 75 Query: 239 HGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 F+KG + S+ +V F+ EEL + + Sbjct: 76 RAFWKGHVPAQILSIGYGAVQFLAFEELTELL 107
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 60.5 bits (145), Expect = 5e-09 Identities = 45/164 (27%), Positives = 75/164 (45%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSK 468 L+ + L + P GT R+ GI+G ++G+ +I V L K Sbjct: 38 LQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGK 97 Query: 467 RLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY 288 +LQ K P+ ++ ++F G ++ + T + P +K LQ + G S+Y Sbjct: 98 KLQQKH-----PEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGE---SKY 149 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 TGTLD K+ + G+ G YKG +++ V A+ + FM E L Sbjct: 150 TGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWL 193 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/154 (29%), Positives = 76/154 (49%), Gaps = 2/154 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 GT+ +++Y+E GI G +KG + TL+ V + FM YE L + GKR + Sbjct: 151 GTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPE--GKRVSE-- 206 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAILKMIRYE 246 ++A + + G IA + V P V+KSR Q +Y G D + ++IR E Sbjct: 207 LSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPP------GKYPNGFRDVLRELIRDE 260 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G+ YKG ++++ A + F+ E +KF+ Sbjct: 261 GVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/75 (32%), Positives = 35/75 (46%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 K I+ ++ L G + V +PL VK RLQ + Y+GT D K + Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFR 65 Query: 248 EGLHGFYKGMGTKIV 204 EG+ G Y+GM I+ Sbjct: 66 EGITGLYRGMAAPII 80
>YG2O_YEAST (P53257) Putative mitochondrial carrier YGR096W| Length = 314 Score = 60.1 bits (144), Expect = 6e-09 Identities = 44/167 (26%), Positives = 80/167 (47%), Gaps = 3/167 (1%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGT--IQAIREVYRESGISGFWKGLIP-TLIMVCNPSIQFMIYET 477 +K RL + +P+G+ ++ R + + GI FWKG IP +L+ V S QF Y Sbjct: 40 IKIRLQLTPANGLKPFGSQVMEVARSMIKNEGIRSFWKGNIPGSLLYVTYGSAQFSSYSL 99 Query: 476 LSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA 297 ++ L P + ++GA A + +++V+YP V+++RL A ++ + Sbjct: 100 FNRYLT--------PFGLEARLHSLVVGAFAGITSSIVSYPFDVLRTRLVANNQMHSMSI 151 Query: 296 SRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 +R + + + EGL GF+KG + AS++F E + Sbjct: 152 TR------EVRDIWKLEGLPGFFKGSIASMTTITLTASIMFGTYETI 192 Score = 47.8 bits (112), Expect = 3e-05 Identities = 43/163 (26%), Positives = 72/163 (44%), Gaps = 3/163 (1%) Frame = -3 Query: 584 IREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNITAME 408 +R++++ G+ GF+KG I ++ + SI F YET+ KK A Sbjct: 155 VRDIWKLEGLPGFFKGSIASMTTITLTASIMFGTYETIRIYCDENEKTTAAHKKWELATL 214 Query: 407 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 228 G I + A ++T+PL ++ R+Q + K R+ ++G Y Sbjct: 215 NHSAGTIGGVIAKIITFPLETIRRRMQFMNS-------------KHLEKFSRHSSVYGSY 261 Query: 227 KGMGTKIVQSVFAASVLFMVKEELVKFVI--LLVARSRTLLLT 105 KG G FA L ++K+E V + +LVA S+T+ T Sbjct: 262 KGYG-------FARIGLQILKQEGVSSLYRGILVALSKTIPTT 297 Score = 36.6 bits (83), Expect = 0.072 Identities = 21/69 (30%), Positives = 35/69 (50%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 +N+ A + L GA++ L A +T P+ +K RLQ G + ++ MI+ Sbjct: 12 QNVAAWKTLLAGAVSGLLARSITAPMDTIKIRLQLTPANGLKPFG--SQVMEVARSMIKN 69 Query: 248 EGLHGFYKG 222 EG+ F+KG Sbjct: 70 EGIRSFWKG 78
>MFRN1_RAT (Q66H23) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 338 Score = 59.7 bits (143), Expect = 8e-09 Identities = 44/185 (23%), Positives = 85/185 (45%), Gaps = 4/185 (2%) Frame = -3 Query: 656 AHILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYE 480 A ++K RL +S+ + IR V+R G+ F++ L M + SI F+ YE Sbjct: 164 AEVVKQRLQMYNSQHQ---SALSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE 220 Query: 479 TLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG--- 309 L +++ P+++ + G +A A T PL V K+ L ++ + Sbjct: 221 FLQEQVN--------PRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSL 272 Query: 308 RNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVA 129 N + R +G +A + + GL G++KG+ +++ + + ++ + V E F+ Sbjct: 273 ANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQL 332 Query: 128 RSRTL 114 +RTL Sbjct: 333 ENRTL 337 Score = 41.2 bits (95), Expect = 0.003 Identities = 42/168 (25%), Positives = 72/168 (42%), Gaps = 4/168 (2%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGL--IPTLIMVCNPS--IQFMIYE 480 +K R+ L+ + Y +I + R GFW+ L + ++M P+ + F YE Sbjct: 69 VKTRMQSLNPDPKARYTSIYGALK--RIMHTEGFWRPLRGLNVMMMGAGPAHAMYFACYE 126 Query: 479 TLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNA 300 + + L F + + + + G++A L V P VVK RLQ Sbjct: 127 NMKRTLNDV-----FSHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYN------ 175 Query: 299 ASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 S++ L I + R EGL FY+ T++ ++ S+ F+ E L Sbjct: 176 -SQHQSALSCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 222
>MCAT_MACFA (Q8HXY2) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 58.9 bits (141), Expect = 1e-08 Identities = 43/162 (26%), Positives = 73/162 (45%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSK 468 L+ + L + P GT R+ GI G ++G+ +I V L K Sbjct: 38 LQTQPPSLPGQPPMYSGTFDCFRKTLFREGIRGLYRGMAAPIIGVTPMFAVCFFGFGLGK 97 Query: 467 RLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY 288 +LQ K P+ ++ ++F G ++ + T + P +K LQ + G ++Y Sbjct: 98 KLQQKH-----PEDVLSYPQLFAAGMLSGIFTTGIMTPGERIKCLLQIQASSGE---TKY 149 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 TGTLD K+ + G+ G YKG +++ V A+ + FM E Sbjct: 150 TGTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYE 191 Score = 53.9 bits (128), Expect = 4e-07 Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 GT+ +++Y+E GI G +KG + TL+ V + FM YE + + GKR + + Sbjct: 151 GTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKNIFTPE--GKRVSELS 208 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY-TGTLDAILKMIRYE 246 + V + G IA + V P V+KSR Q +Y G D + ++I E Sbjct: 209 VP--RVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPP------GKYPNGFRDVLRELIPDE 260 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G+ YKG ++++ A + F+ E +KF+ Sbjct: 261 GVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/75 (32%), Positives = 35/75 (46%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 K I+ ++ L G + V +PL VK RLQ + Y+GT D K + Sbjct: 6 KPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFR 65 Query: 248 EGLHGFYKGMGTKIV 204 EG+ G Y+GM I+ Sbjct: 66 EGIRGLYRGMAAPII 80
>RIM2_YEAST (P38127) Mitochondrial carrier protein RIM2| Length = 377 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/157 (26%), Positives = 81/157 (51%), Gaps = 10/157 (6%) Frame = -3 Query: 584 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRF------PKKN 423 ++ V R G +G +KGL + + +Q+++YE + KRL +RS ++F K Sbjct: 223 LKSVIRNEGFTGLYKGLSASYLGSVEGILQWLLYEQM-KRLIKERSIEKFGYQAEGTKST 281 Query: 422 ITAMEVFLL----GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 255 ++ + +AK A++ TYP VV++RL +Q N +YTG + + +I Sbjct: 282 SEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRL--RQTPKENGKRKYTGLVQSFKVII 339 Query: 254 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 + EGL Y G+ ++++V + ++F E +++ + Sbjct: 340 KEEGLFSMYSGLTPHLMRTVPNSIIMFGTWEIVIRLL 376 Score = 57.4 bits (137), Expect = 4e-08 Identities = 40/135 (29%), Positives = 60/135 (44%), Gaps = 1/135 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKKNI 420 T+ I VY++ G +KGL P L+ V SI F Y T K F Sbjct: 119 TLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMY-----AKAFNNGQE 173 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 T M + A A T P+ ++K+R+Q + G+ + +Y + D + +IR EG Sbjct: 174 TPMIHLMAAATAGWATATATNPIWLIKTRVQL-DKAGKTSVRQYKNSWDCLKSVIRNEGF 232 Query: 239 HGFYKGMGTKIVQSV 195 G YKG+ + SV Sbjct: 233 TGLYKGLSASYLGSV 247 Score = 33.9 bits (76), Expect = 0.47 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 22/99 (22%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQA--------KQEIGRN--------------AASR 291 F+ G I + VVT P +VK+RLQ+ Q + + A + Sbjct: 56 FVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINYVIQAGTH 115 Query: 290 YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 + TL I + + EG +KG+G +V + A S+ F Sbjct: 116 FKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINF 154
>TXTP_YEAST (P38152) Tricarboxylate transport protein (Citrate transport| protein) (CTP) Length = 299 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/150 (22%), Positives = 77/150 (51%), Gaps = 1/150 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIP-TLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G ++ + R+ G SG ++G++P ++ N +++ Y + +Q + K Sbjct: 154 GVVRNYSSLVRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPK--DKP 211 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 +++ FL+GA + + T PL VK+R+Q+ +++Y+ T++ + + EG Sbjct: 212 LSSGLTFLVGAFSGIVTVYSTMPLDTVKTRMQSLD------STKYSSTMNCFATIFKEEG 265 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELV 153 L F+KG ++ + V + ++F + E+++ Sbjct: 266 LKTFWKGATPRLGRLVLSGGIVFTIYEKVL 295 Score = 35.8 bits (81), Expect = 0.12 Identities = 24/87 (27%), Positives = 40/87 (45%) Frame = -3 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 K ++ + FL G++A +TYP K+RLQ + + ASR L I K + Sbjct: 7 KSDVDPLHSFLAGSLAGAAEACITYPFEFAKTRLQLIDKASK--ASR--NPLVLIYKTAK 62 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFM 171 +G+ Y G I+ + A + F+ Sbjct: 63 TQGIGSIYVGCPAFIIGNTAKAGIRFL 89
>UCP3_CANFA (Q9N2I9) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 58.5 bits (140), Expect = 2e-08 Identities = 47/152 (30%), Positives = 68/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 432 GT+ A R + RE G+ G WKG +P + I+ C + + I + K L FP Sbjct: 160 GTMDAYRTIAREEGVRGLWKGTLPNITRNAIVNCAEMVTYDIIK--EKLLDYHLLTDNFP 217 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 I+A A ATVV P+ VVK+R + +Y LD +LKM+ Sbjct: 218 CHLISAFG-------AGFCATVVASPVDVVKTRYM------NSPPGQYCSPLDCMLKMVT 264 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 EG FYKG ++ V+F+ E+L Sbjct: 265 QEGPTAFYKGFTPSFLRLGTWNVVMFVTYEQL 296 Score = 45.8 bits (107), Expect = 1e-04 Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 5/159 (3%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + SI+ +Y+++ + K S + Sbjct: 60 GVLGTILTMVRTEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDH----SS 115 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 IT L G A P VVK R QA +G + +Y+GT+DA + R EG Sbjct: 116 ITTR--ILAGCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEG 173 Query: 242 LHGFYKGMGTKIVQSVF---AASVLF-MVKEELVKFVIL 138 + G +KG I ++ A V + ++KE+L+ + +L Sbjct: 174 VRGLWKGTLPNITRNAIVNCAEMVTYDIIKEKLLDYHLL 212 Score = 39.7 bits (91), Expect = 0.009 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 3/89 (3%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR---YTGTLDAILKMIRYEGLHG 234 FL A A ++T+PL K RLQ + E A+R Y G L IL M+R EG Sbjct: 17 FLGAGTAACFADLLTFPLDTAKVRLQIQGENQATQAARRIQYRGVLGTILTMVRTEGPRS 76 Query: 233 FYKGMGTKIVQSVFAASVLFMVKEELVKF 147 Y G+ + + + AS+ + + + +F Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQF 105
>GHC1_PONPY (Q5RD81) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 57.4 bits (137), Expect = 4e-08 Identities = 47/130 (36%), Positives = 66/130 (50%) Frame = -3 Query: 611 PRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFP 432 PRP IQ R++ R GI+G +KGL TL+ S+ +Y L L + G+ Sbjct: 166 PRPTA-IQLTRDLLRSRGIAGLYKGLGATLLRDVPLSV---VYFPLFANLN--QLGRPAS 219 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 ++ FL G +A A V P VVK+RLQ+ Q G N + Y+G LD K++R Sbjct: 220 EEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQR-GVNEDT-YSGILDCARKILR 277 Query: 251 YEGLHGFYKG 222 +EG F KG Sbjct: 278 HEGPSAFLKG 287 Score = 41.6 bits (96), Expect = 0.002 Identities = 24/74 (32%), Positives = 35/74 (47%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 K I+ + G IA L +P+ + K+RLQ +Q N YT D ++K IR Sbjct: 4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQ----NGQRMYTSMSDCLIKTIRS 59 Query: 248 EGLHGFYKGMGTKI 207 EG G Y+G + Sbjct: 60 EGYFGMYRGAAVNL 73 Score = 32.0 bits (71), Expect = 1.8 Identities = 38/157 (24%), Positives = 62/157 (39%), Gaps = 25/157 (15%) Frame = -3 Query: 569 RESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGA 390 R G G ++G L +V P + R Q + G++ +T ++ L G Sbjct: 58 RSEGYFGMYRGAAVNLTLV-TPEKAIKLAANDFFRHQLSKDGQK-----LTLLKEMLAGC 111 Query: 389 IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYT----GTLDA---------------- 270 A +VT P+ ++K +LQ + GR AA R G L A Sbjct: 112 GAGTCQVIVTTPMEMLKIQLQ---DAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRP 168 Query: 269 -----ILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 ++R G+ G YKG+G +++ V + V F Sbjct: 169 TAIQLTRDLLRSRGIAGLYKGLGATLLRDVPLSVVYF 205
>GHC1_HUMAN (Q9H936) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 57.4 bits (137), Expect = 4e-08 Identities = 47/130 (36%), Positives = 66/130 (50%) Frame = -3 Query: 611 PRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFP 432 PRP T Q R++ R GI+G +KGL TL+ S+ +Y L L + G+ Sbjct: 166 PRPTAT-QLTRDLLRSRGIAGLYKGLGATLLRDVPFSV---VYFPLFANLN--QLGRPAS 219 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 ++ FL G +A A V P VVK+RLQ+ Q G N + Y+G LD K++R Sbjct: 220 EEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQR-GVNEDT-YSGILDCARKILR 277 Query: 251 YEGLHGFYKG 222 +EG F KG Sbjct: 278 HEGPSAFLKG 287 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/74 (31%), Positives = 35/74 (47%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 K I+ + G IA L +P+ + K+RLQ +Q N YT D ++K +R Sbjct: 4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQ----NGQRVYTSMSDCLIKTVRS 59 Query: 248 EGLHGFYKGMGTKI 207 EG G Y+G + Sbjct: 60 EGYFGMYRGAAVNL 73 Score = 32.7 bits (73), Expect = 1.0 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 23/155 (14%) Frame = -3 Query: 569 RESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGA 390 R G G ++G L +V P + R Q + G++ +T ++ L G Sbjct: 58 RSEGYFGMYRGAAVNLTLV-TPEKAIKLAANDFFRHQLSKDGQK-----LTLLKEMLAGC 111 Query: 389 IAKLGATVVTYPLLVVKSRLQ-----------------------AKQEIGRNAASRYTGT 279 A +VT P+ ++K +LQ A+ + AA R T T Sbjct: 112 GAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTAT 171 Query: 278 LDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 ++R G+ G YKG+G +++ V + V F Sbjct: 172 -QLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYF 205
>UCP3_HUMAN (P55916) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 312 Score = 57.4 bits (137), Expect = 4e-08 Identities = 48/160 (30%), Positives = 71/160 (44%), Gaps = 5/160 (3%) Frame = -3 Query: 620 SEKPRPY-GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQS 456 S R Y GT+ A R + RE G+ G WKG +P + I+ C + + I + K L Sbjct: 153 SRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILK--EKLLDY 210 Query: 455 KRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL 276 FP ++A A ATVV P+ VVK+R + +Y L Sbjct: 211 HLLTDNFPCHFVSAFG-------AGFCATVVASPVDVVKTRYM------NSPPGQYFSPL 257 Query: 275 DAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 D ++KM+ EG FYKG ++ V+F+ E+L Sbjct: 258 DCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297 Score = 36.6 bits (83), Expect = 0.072 Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Frame = -3 Query: 413 MEVFLLGA-IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR---YTGTLDAILKMIRYE 246 M V LGA A A +VT+PL K RLQ + E +R Y G L IL M+R E Sbjct: 13 MAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTE 72 Query: 245 GLHGFYKGMGTKIVQSVFAASV 180 G Y G+ + + + AS+ Sbjct: 73 GPCSPYNGLVAGLQRQMSFASI 94
>MFRN1_MOUSE (Q920G8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 338 Score = 57.0 bits (136), Expect = 5e-08 Identities = 43/185 (23%), Positives = 84/185 (45%), Gaps = 4/185 (2%) Frame = -3 Query: 656 AHILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYE 480 A ++K RL +S+ + IR V+R G+ F++ L M + SI F+ YE Sbjct: 164 AEVVKQRLQMYNSQHQSAFS---CIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE 220 Query: 479 TLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG--- 309 L +++ P+++ + G +A A T PL V K+ L ++ + Sbjct: 221 FLQEQVN--------PRRDYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENMALSL 272 Query: 308 RNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVA 129 N + R +G +A + + GL G++KG+ +++ + + ++ + V E + Sbjct: 273 ANVSGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYILTKRQL 332 Query: 128 RSRTL 114 +RTL Sbjct: 333 ENRTL 337
>DIF1_CAEEL (Q27257) Protein dif-1| Length = 312 Score = 56.6 bits (135), Expect = 7e-08 Identities = 39/156 (25%), Positives = 69/156 (44%) Frame = -3 Query: 617 EKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKR 438 EKP+ G + ++ + G +KG+ L+ V F + K LQ Sbjct: 42 EKPQFTGALDCVKRTVSKEGFFALYKGMAAPLVGVSPLFAVFFGGCAVGKWLQQTD---- 97 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM 258 P + +T ++ GA+A + T+V P +K LQ +Q + Y G LD + K+ Sbjct: 98 -PSQEMTFIQNANAGALAGVFTTIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKL 156 Query: 257 IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 + G+ Y+G G +++ + A++ V E L K Sbjct: 157 YKQGGISSIYRGTGATLLRDIPASAAYLSVYEYLKK 192 Score = 38.9 bits (89), Expect = 0.015 Identities = 19/67 (28%), Positives = 30/67 (44%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 F+ G + +V +P VK R+Q ++TG LD + + + EG YK Sbjct: 8 FIAGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYK 67 Query: 224 GMGTKIV 204 GM +V Sbjct: 68 GMAAPLV 74
>UCP3_MOUSE (P56501) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 56.6 bits (135), Expect = 7e-08 Identities = 54/174 (31%), Positives = 80/174 (45%), Gaps = 6/174 (3%) Frame = -3 Query: 635 LAKLDSEKPRPY-GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLS 471 + +L + R Y GT+ A R + RE G+ G WKG P + I+ C + + I + Sbjct: 144 MIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIK--E 201 Query: 470 KRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA-S 294 K L+S FP ++A A ATVV P+ VVK+R NA Sbjct: 202 KLLESHLFTDNFPCHFVSAFG-------AGFCATVVASPVDVVKTRYM-------NAPLG 247 Query: 293 RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLV 132 RY L +LKM+ EG FYKG ++ + A +V+ V E +K ++ V Sbjct: 248 RYRSPLHCMLKMVAQEGPTAFYKGFVPSFLR-LGAWNVMMFVTYEQLKRALMKV 300 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 5/155 (3%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + SI+ +Y+++ + K + + Sbjct: 57 GVLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGADH-----S 111 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 A+ + L G A P VVK R QA +G +Y GT+DA + R EG Sbjct: 112 SVAIRI-LAGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEG 170 Query: 242 LHGFYKGMGTKIVQSVF---AASVLF-MVKEELVK 150 + G +KG I ++ A V + ++KE+L++ Sbjct: 171 VRGLWKGTWPNITRNAIVNCAEMVTYDIIKEKLLE 205 Score = 40.4 bits (93), Expect = 0.005 Identities = 27/91 (29%), Positives = 44/91 (48%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 T + FL A A ++T+PL K RLQ + E + +Y G L IL M+R EG Sbjct: 12 TTVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGAQSVQYRGVLGTILTMVRTEGP 71 Query: 239 HGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 Y G+ + + + AS+ + + + +F Sbjct: 72 RSPYSGLVAGLHRQMSFASIRIGLYDSVKQF 102
>UCP3_BOVIN (O77792) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 56.2 bits (134), Expect = 9e-08 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 432 GT+ A R + RE G+ G WKG++P + I+ C + + I + K L FP Sbjct: 160 GTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCGEMVTYDIIK--EKLLDYHLLTDNFP 217 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 ++A A AT+V P+ VVK+R + +Y D +LKM+ Sbjct: 218 CHFVSAFG-------AGFCATLVASPVDVVKTRYM------NSPPGQYHSPFDCMLKMVT 264 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 EG FYKG ++ V+F+ E++ Sbjct: 265 QEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQM 296 Score = 46.6 bits (109), Expect = 7e-05 Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 5/170 (2%) Frame = -3 Query: 632 AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQS 456 A L + + G + I + R G + GL+ L + SI+ +Y+++ + Sbjct: 49 AALAARSAQYRGVLGTILTMVRTEGPRSLYSGLVAGLQRQMSFASIRIGLYDSVKQFYTP 108 Query: 455 KRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL 276 K S + + + L G A P VVK R QA G +Y+GT+ Sbjct: 109 KGSD------HSSIITRILAGCTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTM 162 Query: 275 DAILKMIRYEGLHGFYKGMGTKIVQSVFA----ASVLFMVKEELVKFVIL 138 DA + R EG+ G +KG+ I ++ ++KE+L+ + +L Sbjct: 163 DAYRTIAREEGVRGLWKGILPNITRNAIVNCGEMVTYDIIKEKLLDYHLL 212 Score = 41.6 bits (96), Expect = 0.002 Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 3/89 (3%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR---YTGTLDAILKMIRYEGLHG 234 FL A A ++T+PL K RLQ + E A+R Y G L IL M+R EG Sbjct: 17 FLAAGTAACFADLLTFPLDTAKVRLQIQGENQAALAARSAQYRGVLGTILTMVRTEGPRS 76 Query: 233 FYKGMGTKIVQSVFAASVLFMVKEELVKF 147 Y G+ + + + AS+ + + + +F Sbjct: 77 LYSGLVAGLQRQMSFASIRIGLYDSVKQF 105
>UCP3_PIG (O97649) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 56.2 bits (134), Expect = 9e-08 Identities = 44/152 (28%), Positives = 68/152 (44%), Gaps = 4/152 (2%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRLQSKRSGKRFP 432 GT+ A R + RE G+ G WKG++P + I+ C + + + ++ K Sbjct: 157 GTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCAEMVTYDV-------IKEKVLDYHLL 209 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 N+ V GA ATVV P+ VVK+R + +Y LD +LKM+ Sbjct: 210 TDNLPCHFVSAFGA--GFCATVVASPVDVVKTRYM------NSPPGQYQNPLDCMLKMVT 261 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 EG FYKG ++ V+F+ E+L Sbjct: 262 QEGPTAFYKGFTPSFLRLGSWNVVMFVSYEQL 293 Score = 45.4 bits (106), Expect = 2e-04 Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 5/159 (3%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + SI+ +Y+++ + K S + Sbjct: 57 GVLGTILTMVRNEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDH----SS 112 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 IT L G A P VVK R QA G + +Y+GT+DA + R EG Sbjct: 113 ITTR--ILAGCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEG 170 Query: 242 LHGFYKGMGTKIVQSVF---AASVLF-MVKEELVKFVIL 138 + G +KG+ I ++ A V + ++KE+++ + +L Sbjct: 171 VRGLWKGILPNITRNAIVNCAEMVTYDVIKEKVLDYHLL 209 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = -3 Query: 407 VFLLGA-IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 V LLGA A A ++T+PL K RLQ + E +++Y G L IL M+R EG Sbjct: 15 VKLLGAGTAACFADLLTFPLDTAKVRLQIQGENQAARSAQYRGVLGTILTMVRNEGPRSP 74 Query: 230 YKGMGTKIVQSVFAASV 180 Y G+ + + + AS+ Sbjct: 75 YNGLVAGLQRQMSFASI 91
>ADT_SCHPO (Q09188) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 322 Score = 55.8 bits (133), Expect = 1e-07 Identities = 37/142 (26%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ YR G+ G ++G P+++ +V + F +Y+TL + F Sbjct: 177 GLVDVYRKTYRSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLVGPLEGNF---- 232 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + FLLG G+ V +YPL ++ R+ + A +Y+ + + +++ EG Sbjct: 233 ---LASFLLGWAVTTGSGVASYPLDTIRRRMM----MTSGEAVKYSSSFECGRQILAKEG 285 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 F+KG G I++ V A VL Sbjct: 286 ARSFFKGAGANILRGVAGAGVL 307 Score = 38.9 bits (89), Expect = 0.015 Identities = 34/174 (19%), Positives = 66/174 (37%), Gaps = 5/174 (2%) Frame = -3 Query: 644 KDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSK 468 +D + + R G + + E G+ W+G ++ ++ F + K Sbjct: 58 QDEMIRAGRLSHRYKGIGECFKRTAAEEGVISLWRGNTANVLRYFPTQALNFAFKDKFKK 117 Query: 467 RLQSKRSGKRFPK---KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA 297 K+ + K N+ + G A + + Y L ++RL + + Sbjct: 118 MFGYKKERDGYAKWFAGNLAS------GGAAGAASLLFVYSLDYARTRLANDAKSAKKGG 171 Query: 296 SR-YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 R + G +D K R +GL G Y+G G +V V + F + + L V++ Sbjct: 172 ERQFNGLVDVYRKTYRSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLV 225
>COLT_DROME (Q9VQG4) Congested-like trachea protein| Length = 306 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/154 (25%), Positives = 70/154 (45%) Frame = -3 Query: 617 EKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKR 438 E+P GT + + G+ G +KG+ L V L KRLQ + + Sbjct: 53 EQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFAGYALGKRLQQRGEDAK 112 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM 258 +T ++F+ G+ + L +T++ P +K LQ +Q G+ +Y G +D K+ Sbjct: 113 -----LTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQ--GQGGERKYNGMIDCAGKL 165 Query: 257 IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 + GL +KG +++ + A + F+V E L Sbjct: 166 YKEGGLRSVFKGSCATMLRDLPANGLYFLVYEAL 199 Score = 42.4 bits (98), Expect = 0.001 Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Frame = -3 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 ++ ++ FL G + + +PL +K RLQ Y GT D K I+ Sbjct: 10 ERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIK 69 Query: 251 YEGLHGFYKGMGTKI--VQSVFA 189 EG+ G YKGM + V +FA Sbjct: 70 NEGVRGLYKGMSAPLTGVAPIFA 92
>AGC1_YEAST (Q12482) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 902 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 1/128 (0%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++ ++ G+ G + G+ L+ V +I F Y L K L + + + E+ Sbjct: 672 QIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPNDKTKRNRLKTWELL 731 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 222 GAIA + A +T P V+K+RLQ R ++Y G AI +++ E F+KG Sbjct: 732 TAGAIAGMPAAFLTTPFDVIKTRLQIDP---RKGETKYNGIFHAIRTILKEESFRSFFKG 788 Query: 221 MGTKIVQS 198 G ++++S Sbjct: 789 GGARVLRS 796 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/68 (39%), Positives = 47/68 (69%), Gaps = 1/68 (1%) Frame = -3 Query: 404 FLLGAIAK-LGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 228 F LG+IA +GATVV YP+ +K+R+QA++ + ++Y ++D +LK+I EG+ G Y Sbjct: 534 FSLGSIAGCIGATVV-YPIDFIKTRMQAQRSL-----AQYKNSIDCLLKIISREGIKGLY 587 Query: 227 KGMGTKIV 204 G+G +++ Sbjct: 588 SGLGPQLI 595 Score = 46.2 bits (108), Expect = 9e-05 Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 1/150 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 +I + ++ GI G + GL P LI V +I+ + + + RL K +GK + Sbjct: 570 SIDCLLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTVNDFMRNRLTDK-NGK------L 622 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 + + GA A + T PL +VK RLQ + + + T I+K + GL Sbjct: 623 SLFPEIISGASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQANETATQIVKKL---GL 679 Query: 239 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 G Y G+ +++ V +++ F L K Sbjct: 680 RGLYNGVAACLMRDVPFSAIYFPTYAHLKK 709
>CMC1_YEAST (P48233) Calcium-binding mitochondrial carrier SAL1 (Suppressor of| AAC2 lethality) Length = 545 Score = 55.1 bits (131), Expect = 2e-07 Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 4/182 (2%) Frame = -3 Query: 671 VNSMDAHILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQ 495 V +D + + A LD++ Q ++++RE G+ F++G+ ++ + ++ Sbjct: 365 VYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGLRLFYRGVTVGIVGIFPYAALD 424 Query: 494 FMIYETLSKRLQSKRSGK-RFPKKNITAMEVFLL--GAIAKLGATVVTYPLLVVKSRLQA 324 + L K +K++ P+ +T + +L GA + V YP+ ++++RLQA Sbjct: 425 LGTFSALKKWYIAKQAKTLNLPQDQVTLSNLVVLPMGAFSGTVGASVVYPINLLRTRLQA 484 Query: 323 KQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 + Y G D +LK + EG G +KG+ + + A S+ ++ E L KF+ Sbjct: 485 QGTYAHPYV--YNGFKDVLLKTLEREGYQGLFKGLVPTLAKVCPAVSISYLCYENLKKFM 542 Query: 143 IL 138 L Sbjct: 543 NL 544
>SFC1_YEAST (P33303) Succinate/fumarate mitochondrial transporter (Regulator of| acetyl-CoA synthetase activity) Length = 322 Score = 54.7 bits (130), Expect = 3e-07 Identities = 44/162 (27%), Positives = 75/162 (46%), Gaps = 4/162 (2%) Frame = -3 Query: 617 EKPRPYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGK 441 E +P G I+ R +Y++ G +KGL +I ++ +I+F YE L +K SG Sbjct: 48 EHVKPPGFIKTGRTIYQKEGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESGI 107 Query: 440 RFPKKNITAMEVFLLGAIAKLG-ATVVTYPLLVVKSRLQAKQEIGR--NAASRYTGTLDA 270 ++ F+ G A + A +V P+ VVK RLQA+ NA +Y + A Sbjct: 108 ------VSTGNTFVAGVGAGITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHA 161 Query: 269 ILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 +++ EG+ Y+G+ + F V +L +F+ Sbjct: 162 AYTIVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFL 203 Score = 46.2 bits (108), Expect = 9e-05 Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 1/151 (0%) Frame = -3 Query: 611 PRPYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRF 435 P+ I A + +E G+S ++G+ T N F +Y L + LQ+ Sbjct: 153 PKYNNAIHAAYTIVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMDVL 212 Query: 434 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 255 P + E +G I+ PL +K+RLQ + I S + +++ Sbjct: 213 P-----SWETSCIGLISGAIGPFSNAPLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLL 267 Query: 254 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 + EG YKG+ ++++ +V F V E Sbjct: 268 KEEGFRALYKGITPRVMRVAPGQAVTFTVYE 298
>AGC1_ASHGO (Q75AH6) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 911 Score = 54.7 bits (130), Expect = 3e-07 Identities = 29/109 (26%), Positives = 65/109 (59%), Gaps = 2/109 (1%) Frame = -3 Query: 524 LIMVCNPS-IQFMIYETLSKRLQSK-RSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPL 351 ++ + NP+ + +++ +R++S+ RS + ++ F LG++A +V YP+ Sbjct: 485 IMKIVNPNYLNDLVHHMELRRIESESRSSNLYFYPIFDSIYNFTLGSVAGCIGAMVVYPI 544 Query: 350 LVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIV 204 +VK+R+QA+++ S+Y ++D +LK++ EG+ G Y G+G +++ Sbjct: 545 DMVKTRMQAQRDF-----SKYKNSIDCLLKILSKEGVRGLYSGLGPQLI 588 Score = 46.2 bits (108), Expect = 9e-05 Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 +I + ++ + G+ G + GL P LI V +I+ + + + L + P + I Sbjct: 563 SIDCLLKILSKEGVRGLYSGLGPQLIGVAPEKAIKLTVNDHMRATLAGRDGKLSLPCEII 622 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 + GA A V T PL +VK RLQ K + +AA + I + GL Sbjct: 623 S-------GATAGACQVVFTNPLEIVKIRLQVKSDYVADAARNSVNAISVIKNL----GL 671 Query: 239 HGFYKGMGTKIVQSVFAASVLF 174 G Y+G G +++ + +++ F Sbjct: 672 IGLYRGAGACLLRDIPFSAIYF 693 Score = 45.4 bits (106), Expect = 2e-04 Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 5/156 (3%) Frame = -3 Query: 650 ILKDRL-AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYET 477 I+K RL K D ++ AI V + G+ G ++G L+ + +I F Y Sbjct: 640 IVKIRLQVKSDYVADAARNSVNAI-SVIKNLGLIGLYRGAGACLLRDIPFSAIYFPTYAH 698 Query: 476 LSKRL---QSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGR 306 + + K S KR + ++ + G +A + A +T P V+K+RLQ + G Sbjct: 699 IKSNVFNFDPKDSDKR---NKLNTWQLLVSGGLAGMPAAFLTTPFDVIKTRLQIDPKKGE 755 Query: 305 NAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQS 198 + Y G DA +++ EG+ F+KG ++++S Sbjct: 756 SV---YNGIWDAARTILKEEGIKSFFKGGPARVLRS 788
>GHC1_MOUSE (Q9D6M3) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 54.3 bits (129), Expect = 3e-07 Identities = 48/130 (36%), Positives = 64/130 (49%) Frame = -3 Query: 611 PRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFP 432 PRP T Q R++ R GI+G +KGL TL+ SI +Y L L + G+ Sbjct: 166 PRPTAT-QLTRDLLRNHGIAGLYKGLGATLLRDVPFSI---VYFPLFANLN--QLGRPSS 219 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 ++ FL G +A A V P VVK+RLQ+ E G N Y+G LD K+ R Sbjct: 220 EEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQS-LERGVN-EDTYSGFLDCARKIWR 277 Query: 251 YEGLHGFYKG 222 +EG F KG Sbjct: 278 HEGPSAFLKG 287 Score = 39.7 bits (91), Expect = 0.009 Identities = 23/74 (31%), Positives = 34/74 (45%) Frame = -3 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 K I+ + G IA L +P+ + K+RLQ +Q N Y D ++K IR Sbjct: 4 KQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQ----NGQRMYASMSDCLIKTIRS 59 Query: 248 EGLHGFYKGMGTKI 207 EG G Y+G + Sbjct: 60 EGYFGMYRGAAVNL 73
>UCP3_RAT (P56499) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 53.9 bits (128), Expect = 4e-07 Identities = 50/166 (30%), Positives = 74/166 (44%), Gaps = 6/166 (3%) Frame = -3 Query: 635 LAKLDSEKPRPY-GTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLS 471 + +L + R Y GT+ A R + RE G+ G WKG P + I+ C + + I + Sbjct: 144 MIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIK--E 201 Query: 470 KRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA-S 294 K L S FP ++A A ATVV P+ VVK+R NA Sbjct: 202 KLLDSHLFTDNFPCHFVSAFG-------AGFCATVVASPVDVVKTRYM-------NAPPG 247 Query: 293 RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 RY L +L+M+ EG FYKG ++ ++F+ E+L Sbjct: 248 RYRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQL 293 Score = 42.7 bits (99), Expect = 0.001 Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + SI+ +Y+++ + K + + Sbjct: 57 GVLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDH-----S 111 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 A+ + L G A P VVK R QA +G +Y GT+DA + R EG Sbjct: 112 SVAIRI-LAGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEG 170 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 + G +KG I ++ + MV +++K +L Sbjct: 171 VRGLWKGTWPNITRNAI-VNCAEMVTYDIIKEKLL 204 Score = 40.0 bits (92), Expect = 0.007 Identities = 27/91 (29%), Positives = 44/91 (48%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 T + FL A A ++T+PL K RLQ + E + +Y G L IL M+R EG Sbjct: 12 TTVVKFLGAGTAACFADLLTFPLDTAKVRLQIQGENPGVQSVQYRGVLGTILTMVRTEGP 71 Query: 239 HGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 Y G+ + + + AS+ + + + +F Sbjct: 72 RSPYSGLVAGLHRQMSFASIRIGLYDSVKQF 102
>ADT_CHLKE (P31692) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 339 Score = 53.5 bits (127), Expect = 6e-07 Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 4/139 (2%) Frame = -3 Query: 611 PRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGK--- 441 PR G + V E G++ FW+G + ++ ++ K L K S K Sbjct: 84 PRYTGIVNCFVRVSSEQGVASFWRGNLANVVRYFPTQAFNFAFKDTIKGLFPKYSPKTDF 143 Query: 440 -RFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 RF N+ + G +A G+ ++ YPL ++RL A ++G + +TG +D + Sbjct: 144 WRFFVVNLAS------GGLAGAGSLLIVYPLDFARTRLAA--DVGSGKSREFTGLVDCLS 195 Query: 263 KMIRYEGLHGFYKGMGTKI 207 K+++ G Y+G G + Sbjct: 196 KVVKRGGPMALYQGFGVSV 214 Score = 46.2 bits (108), Expect = 9e-05 Identities = 39/166 (23%), Positives = 76/166 (45%), Gaps = 3/166 (1%) Frame = -3 Query: 632 AKLDSEKPRPY-GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRL- 462 A + S K R + G + + +V + G ++G + ++ F +Y+T L Sbjct: 177 ADVGSGKSREFTGLVDCLSKVVKRGGPMALYQGFGVSVQGIIVYRGAYFGLYDTAKGVLF 236 Query: 461 QSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTG 282 + +R+ F K + + GA V++YP V+ RL + +Y G Sbjct: 237 KDERTANFFAK--------WAVAQAVTAGAGVLSYPFDTVRRRLMMQS----GGERQYNG 284 Query: 281 TLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 T+D K+ + EG+ F+KG + +++ A VL ++ +E+ KF+ Sbjct: 285 TIDCWRKVAQQEGMKAFFKGAWSNVLRGAGGAFVL-VLYDEIKKFI 329
>ARG13_NEUCR (Q01356) Amino acid transporter arg-13| Length = 363 Score = 53.5 bits (127), Expect = 6e-07 Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 23/179 (12%) Frame = -3 Query: 614 KPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKR 438 + R I I+E++R G+ GFW G + TLI + F ET SK + R+ + Sbjct: 183 RQRQLKPIPVIKEIFRHEGLRGFWHGQLGTLIREAGGCAAWFGSKETTSKWFRG-RNERA 241 Query: 437 FPKKNITAMEVF-------------LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA 297 K+ + EV + GA A + + +P VKSR+Q IG Sbjct: 242 LLKRGASQEEVVASRERPLPLWQQAIAGASAGMSYNFLFFPADTVKSRMQT-SPIGGGGD 300 Query: 296 SRYTGTLDAILK---------MIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 + G + K + + G+ GFY+G G +++S +++ +FMV + L K+ Sbjct: 301 NGGKGAATMMPKKSFGEEARALWKQAGIKGFYRGCGITVLRSAPSSAFIFMVYDGLKKY 359 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/169 (21%), Positives = 70/169 (41%), Gaps = 2/169 (1%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLS 471 +K RL P Y G + R+ R G G ++G+ L+ + +E + Sbjct: 66 VKVRLQSQPDHLPLRYTGPLDCFRQSIRADGFLGLYRGISAPLVGAALENSSLFFFERIG 125 Query: 470 KRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG-RNAAS 294 + L SG ++ ++ G + +++ P+ +VK ++Q E G A Sbjct: 126 RSLLYS-SGFAPRDSELSLSALWFTGGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQ 184 Query: 293 RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 R + I ++ R+EGL GF+ G +++ + F KE K+ Sbjct: 185 RQLKPIPVIKEIFRHEGLRGFWHGQLGTLIREAGGCAAWFGSKETTSKW 233 Score = 46.6 bits (109), Expect = 7e-05 Identities = 27/81 (33%), Positives = 42/81 (51%) Frame = -3 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 237 A+E + G+ A + + YP VK RLQ++ + + RYTG LD + IR +G Sbjct: 42 ALEDIVYGSAAGIVGKYIEYPFDTVKVRLQSQPD---HLPLRYTGPLDCFRQSIRADGFL 98 Query: 236 GFYKGMGTKIVQSVFAASVLF 174 G Y+G+ +V + S LF Sbjct: 99 GLYRGISAPLVGAALENSSLF 119
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein| Length = 292 Score = 52.8 bits (125), Expect = 1e-06 Identities = 40/156 (25%), Positives = 66/156 (42%), Gaps = 1/156 (0%) Frame = -3 Query: 620 SEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSG 444 S K + + I+ + E G++G W+G T I + F YE + K L+ + S Sbjct: 144 SAKTKHTKVLPTIKAIITERGLAGLWQGQSGTFIRESFGGVAWFATYEIVKKSLKDRHSL 203 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 + E+ + G A L +P VKS +Q + NA + G Sbjct: 204 DDPKRDESKIWELLISGGSAGLAFNASIFPADTVKSVMQTEHISLTNAVKKIFGKF---- 259 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 GL GFY+G+G + ++V A + +F + E L Sbjct: 260 ------GLKGFYRGLGITLFRAVPANAAVFYIFETL 289 Score = 32.0 bits (71), Expect = 1.8 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL-HGFYKGM 219 G+IA V+ +P VK RLQ + A++ + T I + EG+ GF++G+ Sbjct: 20 GSIAGACGKVIEFPFDTVKVRLQTQ------ASNVFPTTWSCIKFTYQNEGIARGFFQGI 73 Query: 218 GTKIVQSVFAASVLFMVKEELVKFV 144 + +V + + LF+ + KF+ Sbjct: 74 ASPLVGACLENATLFVSYNQCSKFL 98
>CMC3_CAEEL (Q19529) Probable calcium-binding mitochondrial carrier F17E5.2| Length = 531 Score = 52.4 bits (124), Expect = 1e-06 Identities = 40/168 (23%), Positives = 78/168 (46%), Gaps = 1/168 (0%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETL 474 ++K RLA L G ++Y + GI F+KG +P L+ ++ I +YE+L Sbjct: 363 VMKTRLA-LRRTGQLDKGMFHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGIDLTVYESL 421 Query: 473 SKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS 294 + P + + G + + +YPL +V++RLQA+ +N+ Sbjct: 422 KSMYTKYYTEHTEPG----VLALLACGTCSSTCGQLASYPLALVRTRLQARAISPKNSTQ 477 Query: 293 RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 T + +++ EG G Y+G+ ++ + A S+ ++V E++ K Sbjct: 478 PDT-MVGQFKHILQTEGFTGLYRGITPNFMKVIPAVSISYVVYEKVRK 524
>ADT1_GOSHI (O22342) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 386 Score = 52.4 bits (124), Expect = 1e-06 Identities = 35/142 (24%), Positives = 68/142 (47%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ + GI+G ++G I + ++ + F +Y++L L + F Sbjct: 236 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVLLTGSMQDSF---- 291 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 F+LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 292 ---FASFVLGWLITNGAALASYPIDTVRRRMMMTS----GKAVKYKSSLDAFSQILKNEG 344 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 +KG G+ I++++ A VL Sbjct: 345 GKSLFKGAGSNILRAIAGAGVL 366
>UCP5_MOUSE (Q9Z2B2) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 52.4 bits (124), Expect = 1e-06 Identities = 41/151 (27%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRL-QSKRSGKRFPKKNITA 414 ++Y++ G G W+G++PT I+V ++ +Y+ K L S G +++ Sbjct: 186 DIYQQEGTRGLWRGVVPTAQRAAIVV---GVELPVYDITKKHLIVSGMLGDTILTHFVSS 242 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 L GA+A + P+ VV++R+ ++ I + Y GTLD ILKM ++EG Sbjct: 243 FTCGLAGALA-------SNPVDVVRTRMMNQRAIVGHV-DLYKGTLDGILKMWKHEGFFA 294 Query: 233 FYKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 YKG ++ + F+ E+L + I Sbjct: 295 LYKGFWPNWLRLGPWNIIFFITYEQLKRLQI 325 Score = 36.2 bits (82), Expect = 0.094 Identities = 21/90 (23%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAK-QEIG-RNAASRYTGTLDAILKMIRYEGLHGF 231 F+ G +A + A T+P+ + K+RLQ + Q I R +Y G A+ ++ + EG+ Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILAL 103 Query: 230 YKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 Y G+ +++ ++ + + L + + Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFV 133
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2| Length = 307 Score = 52.0 bits (123), Expect = 2e-06 Identities = 38/163 (23%), Positives = 73/163 (44%), Gaps = 2/163 (1%) Frame = -3 Query: 629 KLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQS 456 ++ K G + +++ + GI G +KG+ T+ + N +IY+ + + Sbjct: 145 RMQDVKSSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNALWNGGYFGVIYQVRNSMPVA 204 Query: 455 KRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL 276 K G++ + GAI T++ P VVKSR+Q+ + +A +Y L Sbjct: 205 KTKGQK-------TRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVDAVS-SAVKKYNWCL 256 Query: 275 DAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 ++L + R EG YKG K+ + S++ +V ++ F Sbjct: 257 PSLLVIYREEGFRALYKGFVPKVCRLAPGGSLMLVVFTGMMNF 299 Score = 46.6 bits (109), Expect = 7e-05 Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA-----SRYTGTLDAILKMIRYEGL 240 F+ GA+A + V YPL VVK+R Q + AA RY G +D + K+++ EG Sbjct: 16 FISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEGF 75 Query: 239 HGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 Y+G+ + ++ + F ++ K Sbjct: 76 SRLYRGISSPMLMEAPKRATKFACNDQYQK 105 Score = 44.3 bits (103), Expect = 3e-04 Identities = 35/147 (23%), Positives = 60/147 (40%), Gaps = 9/147 (6%) Frame = -3 Query: 632 AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM---------VCNPSIQFMIYE 480 A + + R G I ++++ ++ G S ++G+ ++M CN Y+ Sbjct: 50 AAVGKQVERYNGVIDCLKKIVKKEGFSRLYRGISSPMLMEAPKRATKFACNDQ-----YQ 104 Query: 479 TLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNA 300 + K L F T GA A + V P ++K R+Q + Sbjct: 105 KIFKNL--------FNTNETTQKISIAAGASAGMTEAAVIVPFELIKIRMQ-------DV 149 Query: 299 ASRYTGTLDAILKMIRYEGLHGFYKGM 219 S Y G +D + K I+ EG+ G YKG+ Sbjct: 150 KSSYLGPMDCLKKTIKNEGIMGLYKGI 176
>YD1K_SCHPO (Q10248) Putative mitochondrial carrier C4G9.20c| Length = 302 Score = 52.0 bits (123), Expect = 2e-06 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 4/170 (2%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKG-LIPTLIMVCNPSIQFMIYETLS 471 +K RL + P + ++++ + G++ F+KG ++P L + SIQF +E Sbjct: 41 VKVRLQSQSNVSPIYNNALDCVKKISKNEGLAAFYKGTVLPLLGIGFCVSIQFTTFEYC- 99 Query: 470 KRLQSKRSGKRFPKKN---ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNA 300 KRF ++ +T + ++ GAI+ L + + P+ V+ RLQ + G+N Sbjct: 100 ---------KRFFSRDGTPVTMPQYYVSGAISGLANSFLVGPVEHVRIRLQI--QTGKNV 148 Query: 299 ASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 Y G D I K+ GL G KG + + F+ E LVK Sbjct: 149 L--YHGPWDCIKKISSQYGLSGIMKGYNPTAAREAHGLGMYFLAYEALVK 196 Score = 49.3 bits (116), Expect = 1e-05 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 1/154 (0%) Frame = -3 Query: 602 YGTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKK 426 +G I+++ + G+SG KG PT + + F+ YE L K +K + Sbjct: 151 HGPWDCIKKISSQYGLSGIMKGYNPTAAREAHGLGMYFLAYEALVKNTMAKHH--LTDRS 208 Query: 425 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 ++ + GA A + YP +VKS++Q G + + Y + + Sbjct: 209 QTPGWKLCVFGAGAGYAMWLAAYPFDIVKSKIQTD---GFLSKATYKNSWQCAKGIYTKA 265 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 GL GFY+G +V++ A +V F V E + + + Sbjct: 266 GLRGFYRGFVPVLVRAAPANAVTFYVYETVSQHI 299 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 6/100 (6%) Frame = -3 Query: 428 KNITAMEVF------LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 267 KN+ A+ VF L G + +V P VK RLQ++ N + Y LD + Sbjct: 7 KNLLAILVFSFTKDFLAGVSGGVAQVLVGQPFDCVKVRLQSQS----NVSPIYNNALDCV 62 Query: 266 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 K+ + EGL FYKG ++ F S+ F E +F Sbjct: 63 KKISKNEGLAAFYKGTVLPLLGIGFCVSIQFTTFEYCKRF 102
>YFL5_YEAST (P43617) Putative mitochondrial carrier YFR045W| Length = 285 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/147 (25%), Positives = 70/147 (47%), Gaps = 1/147 (0%) Frame = -3 Query: 593 IQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 417 + A++ +Y+ G + F +G T+ + N SIQF Y + LQ++ N Sbjct: 144 LPAVKHMYQTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQAR---------NDK 194 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 237 A V + G +T P+ VVK+R+ ++ NA + Y TL+ + ++ EG+ Sbjct: 195 ASSV-ITGLATSFTLVAMTQPIDVVKTRMMSQ-----NAKTEYKNTLNCMYRIFVQEGMA 248 Query: 236 GFYKGMGTKIVQSVFAASVLFMVKEEL 156 F+KG + ++ + + F V E++ Sbjct: 249 TFWKGSIFRFMKVGISGGLTFTVYEQV 275
>UCP5_HUMAN (O95258) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/151 (26%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTL----IMVCNPSIQFMIYETLSKRL-QSKRSGKRFPKKNITA 414 ++Y++ G G W+G++PT I+V ++ +Y+ K L S G +++ Sbjct: 186 DIYQQEGTRGLWRGVVPTAQRAAIVV---GVELPVYDITKKHLILSGMMGDTILTHFVSS 242 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 L GA+A + P+ VV++R+ ++ I + Y GT+D ILKM ++EG Sbjct: 243 FTCGLAGALA-------SNPVDVVRTRMMNQRAIVGHV-DLYKGTVDGILKMWKHEGFFA 294 Query: 233 FYKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 YKG ++ + F+ E+L + I Sbjct: 295 LYKGFWPNWLRLGPWNIIFFITYEQLKRLQI 325 Score = 36.2 bits (82), Expect = 0.094 Identities = 19/90 (21%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI--GRNAASRYTGTLDAILKMIRYEGLHGF 231 F+ G +A + A T+P+ + K+RLQ + + R +Y G A+ ++ + EG+ Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103 Query: 230 YKGMGTKIVQSVFAASVLFMVKEELVKFVI 141 Y G+ +++ ++ + + L + + Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFV 133
>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1| Length = 695 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 399 V RE G+ G +KG L+ V +I F Y +K + + + G P + A Sbjct: 486 VVRELGLFGLYKGARACLLRDVPFSAIYFPTYAH-TKAMMADKDGYNHPLTLLAA----- 539 Query: 398 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 219 GAIA + A + P V+K+RLQ + R+ + YTG DA K++ EG F+KG Sbjct: 540 -GAIAGVPAASLVTPADVIKTRLQV---VARSGQTTYTGVWDATKKIMAEEGPRAFWKGT 595 Query: 218 GTKIVQS 198 ++ +S Sbjct: 596 AARVFRS 602 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 1/137 (0%) Frame = -3 Query: 581 REVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEV 405 ++V R G G ++GL+P L+ V +I+ + + + +L K K NI Sbjct: 392 KKVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDK-------KGNIPTWAE 444 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 L G A V T PL +VK RLQ EI +G+ ++R GL G YK Sbjct: 445 VLAGGCAGASQVVFTNPLEIVKIRLQVAGEIA-------SGSKIRAWSVVRELGLFGLYK 497 Query: 224 GMGTKIVQSVFAASVLF 174 G +++ V +++ F Sbjct: 498 GARACLLRDVPFSAIYF 514 Score = 42.0 bits (97), Expect = 0.002 Identities = 24/63 (38%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Frame = -3 Query: 404 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 228 F LG+ A +GATVV YP+ +VK+R+Q ++ Y + D K++R+EG G Y Sbjct: 346 FTLGSFAGAVGATVV-YPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLY 404 Query: 227 KGM 219 +G+ Sbjct: 405 RGL 407
>MFRN_CAEEL (Q23125) Mitoferrin| Length = 312 Score = 51.6 bits (122), Expect = 2e-06 Identities = 52/183 (28%), Positives = 84/183 (45%), Gaps = 11/183 (6%) Frame = -3 Query: 656 AHILKDRLAKLDSEKPRPYGT-IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 A ++K R+ S PYG+ ++ R VY G++ F++ L M V +I FM Y Sbjct: 135 AEVVKQRMQMAFS----PYGSSLECARCVYNREGVAAFYRSYTTQLAMNVPFQAIHFMSY 190 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRN 303 E L + K PK ++ A G +A A +T P+ VK+ L +Q + Sbjct: 191 EFWQHVLNPEH--KYDPKSHLIA------GGLAGGLAAALTTPMDCVKTVLNTQQAAEAD 242 Query: 302 AASR---------YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 A+R Y G DA+ + GL GF G+ +++ V A ++ + V EL K Sbjct: 243 PANRRIFLQARYRYRGISDAVRTIYSQRGLSGFSCGLQARVIFQVPATALSWSV-YELFK 301 Query: 149 FVI 141 F++ Sbjct: 302 FML 304
>ORNT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute carrier| family 25 member 2) Length = 301 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/143 (25%), Positives = 67/143 (46%), Gaps = 2/143 (1%) Frame = -3 Query: 584 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI--YETLSKRLQSKRSGKRFPKKNITAM 411 ++ + ++ G GF+ GL TL+ P F YE S RS K + + Sbjct: 157 VKGILKKDGPLGFYHGLSSTLLQE-GPGYFFFFGGYELSRSFFASGRS-----KDELGPV 210 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + L G +A + ++ +P+ +KSR+Q G+ A G + +L ++R EG+ Sbjct: 211 HLMLSGGVAGICLWLIVFPVDCIKSRIQVLSMYGKQA-----GFIGTLLSVVRNEGIVAL 265 Query: 230 YKGMGTKIVQSVFAASVLFMVKE 162 Y G+ +++++ A LF+ E Sbjct: 266 YSGLKATMIRAIPANGALFVAYE 288 Score = 38.5 bits (88), Expect = 0.019 Identities = 24/75 (32%), Positives = 32/75 (42%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA + P +K ++Q ++ Y G D LK GL GFYKG G Sbjct: 16 GAAGGTACVLTGQPFDTIKVKMQTFPDL-------YKGLTDCFLKTYAQVGLRGFYKGTG 68 Query: 215 TKIVQSVFAASVLFM 171 ++ V SVLFM Sbjct: 69 PALMAYVAENSVLFM 83
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 51.2 bits (121), Expect = 3e-06 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 2/154 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKN 423 G I ++++ G+ G ++G N S+Q +IY + G KN Sbjct: 155 GLGNCITKIFKSDGLRGLYQGF--------NVSVQGIIIYRAAYFGVYDTAKGMLPDPKN 206 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 246 + + +++ A +V+YP V+ R+ + GR A YTGT+D K+ + E Sbjct: 207 VHIIVSWMIAQTVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIAKDE 264 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G F+KG + +++ + A VL ++ +E+ KFV Sbjct: 265 GPKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKFV 297 Score = 43.1 bits (100), Expect = 8e-04 Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 426 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 425 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 264 + G +A GA T YPL ++RL A ++G+ AA R +TG + I Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGAAQREFTGLGNCIT 161 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 168 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGV 193
>ADT1_WHEAT (Q41629) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 331 Score = 50.8 bits (120), Expect = 4e-06 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ + GI+G ++G I + ++ + F +Y++L L + Sbjct: 181 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSLKPVLLTGTL-------Q 233 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 234 VCFFASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEG 289 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 +KG G I++++ A VL Sbjct: 290 AKSLFKGAGANILRAIAGAGVL 311
>ADT1_MOUSE (P48962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (mANC1) Length = 297 Score = 50.8 bits (120), Expect = 4e-06 Identities = 37/154 (24%), Positives = 75/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + ++++ G+ G ++G + ++ + F +Y+T L KN Sbjct: 155 GLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDP--------KN 206 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 246 + + +++ A +V+YP V+ R+ + GR A YTGTLD K+ + E Sbjct: 207 VHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTLDCWRKIAKDE 264 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G + F+KG + +++ + A VL ++ +E+ K+V Sbjct: 265 GANAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 39.7 bits (91), Expect = 0.009 Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 426 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 425 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 264 + G +A GA T YPL ++RL A ++G+ ++ R + G D + Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGSSQREFNGLGDCLT 161 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 168 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGV 193
>M2OM_MOUSE (Q9CR62) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 50.8 bits (120), Expect = 4e-06 Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 5/141 (3%) Frame = -3 Query: 629 KLDSEKPRPYGTI-QAIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQ 459 +L +++ R Y + A+ + RE G+ W+G IPT+ +V N + L+ Q Sbjct: 151 RLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAA-------QLASYSQ 203 Query: 458 SKRS--GKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYT 285 SK+ + NI F I+ L T + P+ +VK+R+Q + I + Y Sbjct: 204 SKQFLLDSGYFSDNILCH--FCASMISGLVTTAASMPVDIVKTRIQNMRMI--DGKPEYK 259 Query: 284 GTLDAILKMIRYEGLHGFYKG 222 LD +LK++RYEG +KG Sbjct: 260 NGLDVLLKVVRYEGFFSLWKG 280 Score = 45.1 bits (105), Expect = 2e-04 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 228 FL G +A +GATV PL +VK+R+Q G A +R Y + A+ +++ EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVKNRMQLS---GEGAKTREYKTSFHALTSILKTEGLKGIY 80 Query: 227 KGMGTKIVQ 201 G+ +++ Sbjct: 81 TGLSAGLLR 89
>ADT1_ARATH (P31167) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 381 Score = 50.4 bits (119), Expect = 5e-06 Identities = 35/142 (24%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ + GI+G ++G I + ++ + F +Y+++ L + F Sbjct: 231 GLVDVYRKTLKTDGIAGLYRGFNISCVGIIVYRGLYFGLYDSVKPVLLTGDLQDSF---- 286 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 287 ---FASFALGWVITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFKQILKNEG 339 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 +KG G I+++V A VL Sbjct: 340 AKSLFKGAGANILRAVAGAGVL 361
>ADT1_SOLTU (P25083) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 386 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 1/159 (0%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETL 474 + DR A + + G + ++ + GI+G ++G I + ++ + F +Y++L Sbjct: 219 LANDRKASKKGGERQFNGLVDVYKKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSL 278 Query: 473 SKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS 294 L + F F LG + GA + +YP+ V+ R+ A Sbjct: 279 KPVLLTGNLQDSF-------FASFGLGWLITNGAGLASYPIDTVRRRMMMTS----GEAV 327 Query: 293 RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVL 177 +Y +LDA ++++ EG +KG G I+++V A VL Sbjct: 328 KYKSSLDAFSQIVKNEGPKSLFKGAGANILRAVAGAGVL 366
>YQ51_CAEEL (Q09461) Putative mitochondrial carrier C16C10.1| Length = 360 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 18/139 (12%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKR-FPKK 426 GT AI ++ R GI W GL PT++M ++ F Y+ LS L+ K +R F + Sbjct: 108 GTADAIVKIARHEGIRSLWSGLSPTMVMALPATVFYFTTYDNLSVWLKKKMCCRRAFSPE 167 Query: 425 NITAME---VFLLGAIAKLGATVVTYPLLVVKSRLQAKQ----EIG---------RNAAS 294 T + + G +A+ A V P+ ++++++Q+K+ EIG + +S Sbjct: 168 KWTPPDWSAAAVAGIVARTIAVTVVSPIEMIRTKMQSKRLTYHEIGHLVRSSMATKGISS 227 Query: 293 RYTGTLDAILKMIRYEGLH 237 Y G +L+ I + G++ Sbjct: 228 FYLGWTPTMLRDIPFSGIY 246 Score = 37.4 bits (85), Expect = 0.042 Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 1/144 (0%) Frame = -3 Query: 629 KLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSK 453 K+ S++ + +R GIS F+ G PT++ + I + Y+ LQ + Sbjct: 201 KMQSKRLTYHEIGHLVRSSMATKGISSFYLGWTPTMLRDIPFSGIYWAGYDLFKTNLQRR 260 Query: 452 RSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 273 + P + F+ GA A + A++ T+P V+K+ Q + IG + Sbjct: 261 QGPDHNP-----FVVSFVSGAAAGVVASIFTHPFDVIKTNCQIR--IGGSIDDMNKSITT 313 Query: 272 AILKMIRYEGLHGFYKGMGTKIVQ 201 I M G+ F G+ ++V+ Sbjct: 314 VIKDMYHSRGISAFSSGLVPRLVK 337 Score = 32.3 bits (72), Expect = 1.4 Identities = 14/45 (31%), Positives = 25/45 (55%) Frame = -3 Query: 290 YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 + GT DAI+K+ R+EG+ + G+ +V ++ A F + L Sbjct: 106 FRGTADAIVKIARHEGIRSLWSGLSPTMVMALPATVFYFTTYDNL 150 Score = 30.8 bits (68), Expect = 4.0 Identities = 15/33 (45%), Positives = 21/33 (63%) Frame = -3 Query: 584 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI 486 I+++Y GIS F GL+P L+ V +PS MI Sbjct: 315 IKDMYHSRGISAFSSGLVPRLVKV-SPSCAIMI 346
>OAC1_YEAST (P32332) Mitochondrial oxaloacetate transport protein| (Mitochondrial carrier protein PMT) Length = 324 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/159 (22%), Positives = 68/159 (42%), Gaps = 1/159 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMV-CNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + +++ G+ G ++G+ ++ S+Q IY T L K P + Sbjct: 173 GVWNGLVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMKDGPALH 232 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 +TA I+ LG VV P V+ +R+ ++ Y G +D ++K +R EG Sbjct: 233 LTA------STISGLGVAVVMNPWDVILTRIYNQK------GDLYKGPIDCLVKTVRIEG 280 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVAR 126 + YKG ++ + + E+ +K V + +R Sbjct: 281 VTALYKGFAAQVFRIAPHTIMCLTFMEQTMKLVYSIESR 319 Score = 48.5 bits (114), Expect = 2e-05 Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 11/159 (6%) Frame = -3 Query: 593 IQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 417 IQ + +++ GI G KGL I + + YE + L + P K + Sbjct: 68 IQGMAVIFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRSSLNQLFFPDQEPHKVQS 127 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE-IGRNAASRYTGTLDAILKMIRYEGL 240 GA + + V+ PL +VK+RLQ+ E I + YTG + ++ + + EG+ Sbjct: 128 VGVNVFSGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKTEGV 187 Query: 239 HGFYKGMGTKIVQSVFAASVL---------FMVKEELVK 150 G ++G+ I+++ +SV +VK +L+K Sbjct: 188 KGLFRGIDAAILRTGAGSSVQLPIYNTAKNILVKNDLMK 226 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/89 (26%), Positives = 44/89 (49%) Frame = -3 Query: 461 QSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTG 282 Q K+ K +K I+ F+ G +A A VT P+ ++K R+Q + E+ +AA Y Sbjct: 8 QDKQIEKTAAQK-ISKFGSFVAGGLAACIAVTVTNPIELIKIRMQLQGEMSASAAKVYKN 66 Query: 281 TLDAILKMIRYEGLHGFYKGMGTKIVQSV 195 + + + + EG+ G KG+ + + Sbjct: 67 PIQGMAVIFKNEGIKGLQKGLNAAYIYQI 95
>MFRN_CAEBR (Q620A6) Mitoferrin| Length = 311 Score = 50.4 bits (119), Expect = 5e-06 Identities = 53/183 (28%), Positives = 83/183 (45%), Gaps = 11/183 (6%) Frame = -3 Query: 656 AHILKDRLAKLDSEKPRPYGT-IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 A ++K R+ S PYG+ ++ R VY G + F++ L M V +I FM Y Sbjct: 134 AEVVKQRMQMAYS----PYGSSLECARCVYNREGFAAFYRSYTTQLAMNVPFQAIHFMGY 189 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQ----- 318 E + L + K PK ++ A G +A A VT P+ VK+ L +Q Sbjct: 190 EFWQQVLNPEH--KYDPKSHLIA------GGLAGGLAAAVTTPMDCVKTVLNTQQAAEAD 241 Query: 317 ----EIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 I A RY G DA+ + G+ GF G+ +++ V A ++ + V EL K Sbjct: 242 PSNRRIFLKARYRYRGISDAVRTIYSQRGMAGFSCGLQARVIFQVPATALSWSV-YELFK 300 Query: 149 FVI 141 F++ Sbjct: 301 FML 303
>ORNT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 50.1 bits (118), Expect = 6e-06 Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 2/143 (1%) Frame = -3 Query: 584 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI--YETLSKRLQSKRSGKRFPKKNITAM 411 ++E++R+ G GF+ GL TL+ P F YE S RS K + + Sbjct: 157 VKEIFRKDGPLGFYHGLSSTLLREV-PGYFFFFGGYELSRSFFASGRS-----KDELGPV 210 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + L G + + YP+ +KSR+Q G+ TG + L +++ EG+ Sbjct: 211 PLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQ-----TGLVRTFLSIVKNEGITAL 265 Query: 230 YKGMGTKIVQSVFAASVLFMVKE 162 Y G+ ++++ A LF+ E Sbjct: 266 YSGLKPTMIRAFPANGALFLAYE 288 Score = 35.0 bits (79), Expect = 0.21 Identities = 21/75 (28%), Positives = 31/75 (41%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA + P +K ++Q ++ Y G D LK G GFYKG Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDL-------YRGLTDCCLKTYSQVGFRGFYKGTS 68 Query: 215 TKIVQSVFAASVLFM 171 ++ ++ SVLFM Sbjct: 69 PALIANIAENSVLFM 83
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/154 (24%), Positives = 73/154 (47%), Gaps = 2/154 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKN 423 G + ++++ G+ G ++G N S+Q +IY + G KN Sbjct: 155 GLGNCLTKIFKSDGLRGLYQGF--------NVSVQGIIIYRAAYFGVYDTAKGMLPDPKN 206 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 246 + + +++ A +V+YP V+ R+ + GR A YTGT+D K+ + E Sbjct: 207 VHIIVSWMIAQTVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWKKIAKDE 264 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G F+KG + +++ + A VL ++ +E+ K+V Sbjct: 265 GAKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 40.8 bits (94), Expect = 0.004 Identities = 36/152 (23%), Positives = 65/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 426 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 425 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 264 + G +A GA T YPL ++RL A ++G+ AA R ++G + + Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGAAQREFSGLGNCLT 161 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 168 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGV 193
>ADT1_HUMAN (P12235) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) Length = 297 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/155 (25%), Positives = 73/155 (47%), Gaps = 2/155 (1%) Frame = -3 Query: 602 YGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKK 426 +G I ++++ G+ G ++G N S+Q +IY + G K Sbjct: 154 HGLGDCIIKIFKSDGLRGLYQGF--------NVSVQGIIIYRAAYFGVYDTAKGMLPDPK 205 Query: 425 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRY 249 N+ +++ A +V+YP V+ R+ + GR A YTGT+D K+ + Sbjct: 206 NVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIAKD 263 Query: 248 EGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 EG F+KG + +++ + A VL ++ +E+ K+V Sbjct: 264 EGAKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 43.5 bits (101), Expect = 6e-04 Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 6/150 (4%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRL-----QSKRSGKRF 435 G I + + +E G FW+G + +I ++ K+L + R+ Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRY 111 Query: 434 PKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKM 258 N+ + G A + YPL ++RL A ++G+ AA R + G D I+K+ Sbjct: 112 FAGNLAS------GGAAGATSLCFVYPLDFARTRLAA--DVGKGAAQREFHGLGDCIIKI 163 Query: 257 IRYEGLHGFYKGMGTKIVQSVFAASVLFMV 168 + +GL G Y+G + + + F V Sbjct: 164 FKSDGLRGLYQGFNVSVQGIIIYRAAYFGV 193
>ADT_ORYSA (P31691) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 382 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ + GI+G ++G I + ++ + F +Y++L + + F Sbjct: 232 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVVLTGSLQDNF---- 287 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 F LG + GA + +YP+ V+ R+ A +Y ++DA ++++ EG Sbjct: 288 ---FASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSMDAFSQILKNEG 340 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 +KG G I++++ A VL Sbjct: 341 AKSLFKGAGANILRAIAGAGVL 362
>ADT1_MAIZE (P04709) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 387 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ + GI+G ++G I + ++ + F +Y+++ + + F Sbjct: 237 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGNLQDNF---- 292 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 293 ---FASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEG 345 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 +KG G I++++ A VL Sbjct: 346 PKSLFKGAGANILRAIAGAGVL 367 Score = 35.4 bits (80), Expect = 0.16 Identities = 36/184 (19%), Positives = 69/184 (37%), Gaps = 7/184 (3%) Frame = -3 Query: 671 VNSMDAHILKDRLAKLDSEKPRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ 495 + + D I RL++ PY G + + ++ G S W+G +I Sbjct: 115 IQNQDEMIKSGRLSE-------PYKGIVDCFKRTIKDEGFSSLWRGNTANVIRYFPTQAL 167 Query: 494 FMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGAT-----VVTYPLLVVKSRL 330 ++ KRL + KK+ + G +A GA Y L ++RL Sbjct: 168 NFAFKDYFKRLFNF-------KKDRDGYWKWFAGNLASGGAAGASSLFFVYSLDYARTRL 220 Query: 329 QAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELV 153 + + R + G +D K ++ +G+ G Y+G V + + F + + + Sbjct: 221 ANDAKAAKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIK 280 Query: 152 KFVI 141 V+ Sbjct: 281 PVVL 284
>UCP1_CANFA (Q9GMZ1) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 309 Score = 49.3 bits (116), Expect = 1e-05 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 7/172 (4%) Frame = -3 Query: 650 ILKDRL---AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 ++K RL + L KPR GT A R + G++G WKG P L+ V + + Y Sbjct: 138 VVKVRLQAQSHLHGRKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRNVIINCTELVTY 197 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 + + + L K ++ A ++ FL +A TV++ P+ VVK+R Sbjct: 198 DLMKEAL---------VKNHLLADDLPCHFLSALVAGFCTTVLSSPVDVVKTRFV----- 243 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 + +YT + + M+ EG F+KG ++ ++F+ E+L Sbjct: 244 -NSVPEQYTSVPNCAMTMLTKEGPLAFFKGFVPSFLRLGSWNVIMFVCFEQL 294 Score = 36.6 bits (83), Expect = 0.072 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 3/68 (4%) Frame = -3 Query: 374 ATVVTYPLLVVKSRLQAKQEIGRNA---ASRYTGTLDAILKMIRYEGLHGFYKGMGTKIV 204 A ++T+PL K RLQ + E G+ A RY G L + + R EGL Y G+ + Sbjct: 27 ADMITFPLDTAKVRLQIQGE-GQGQPPRAPRYRGVLGTVATLARTEGLQKLYSGLPAGLQ 85 Query: 203 QSVFAASV 180 + V AS+ Sbjct: 86 RQVGFASL 93
>CG69_MOUSE (Q9D8K8) Mitochondrial carrier protein CGI-69 homolog| Length = 359 Score = 49.3 bits (116), Expect = 1e-05 Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 3/166 (1%) Frame = -3 Query: 638 RLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRL 462 R A + R GT+ A ++ R G W GL TL+M V +I F Y+ L L Sbjct: 93 RCATWFQDPTRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152 Query: 461 --QSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRY 288 QS S P + GA+A++G V PL +V+++LQA+ R AS Sbjct: 153 CGQSLTSDLYAP---------MVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELAS-- 201 Query: 287 TGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 ++ + G + G G ++ V S L+ ELVK Sbjct: 202 -----SVQAAVTQGGWRSLWLGWGPTALRDV-PFSALYWFNYELVK 241 Score = 43.1 bits (100), Expect = 8e-04 Identities = 18/51 (35%), Positives = 33/51 (64%) Frame = -3 Query: 296 SRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 +R+TGTLDA +K++R+EG + G+ +V +V A ++ F ++L F+ Sbjct: 102 TRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
>ADT2_MAIZE (P12857) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 387 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ + GI+G ++G I + ++ + F +Y+++ + + F Sbjct: 237 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGSLQDNF---- 292 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 F LG + GA + +YP+ V+ R+ A +Y +LDA ++++ EG Sbjct: 293 ---FASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQILKKEG 345 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 +KG G I++++ A VL Sbjct: 346 PKSLFKGAGANILRAIAGAGVL 367
>ADT_CHLRE (P27080) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 308 Score = 49.3 bits (116), Expect = 1e-05 Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ GI+G ++G I + +V + F +Y++L + F Sbjct: 158 GLVDVYRKTIASDGIAGLYRGFNISCVGIVVYRGLYFGMYDSLKPVVLVGPLANNF---- 213 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + FLLG +GA + +YP+ ++ R+ +A +Y + ++++ EG Sbjct: 214 ---LAAFLLGWGITIGAGLASYPIDTIRRRMMMTS----GSAVKYNSSFHCFQEIVKNEG 266 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 + +KG G I+++V A VL Sbjct: 267 MKSLFKGAGANILRAVAGAGVL 288
>M2OM_RAT (P97700) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 48.9 bits (115), Expect = 1e-05 Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%) Frame = -3 Query: 629 KLDSEKPRPYGTI-QAIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQ 459 +L +++ R Y + A+ + RE G+ W+G IPT+ +V N + L+ Q Sbjct: 151 RLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAA-------QLASYSQ 203 Query: 458 SKRS--GKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYT 285 SK+ + NI F I+ L T + P+ +VK+R+Q + I Y Sbjct: 204 SKQFLLDSGYFSDNILCH--FCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKP--EYK 259 Query: 284 GTLDAILKMIRYEGLHGFYKG 222 LD +LK++RYEG +KG Sbjct: 260 NGLDVLLKVVRYEGFFSLWKG 280 Score = 43.1 bits (100), Expect = 8e-04 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 228 FL G +A +GATV PL +V +R+Q G A +R Y + A+ +++ EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVXNRMQLS---GEGAKTREYKTSFHALTSILKAEGLRGIY 80 Query: 227 KGMGTKIVQ 201 G+ +++ Sbjct: 81 TGLSAGLLR 89
>ADT_NEUCR (P02723) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 313 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ GI+G ++G P++ +V + F +Y+++ L F Sbjct: 163 GLVDVYRKTIASDGIAGLYRGFGPSVAGIVVYRGLYFGLYDSIKPVLLVGDLKNNF---- 218 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + F LG A + +YPL ++ R+ A +Y + DA +++ EG Sbjct: 219 ---LASFALGWCVTTAAGIASYPLDTIRRRMMMTS----GEAVKYKSSFDAASQIVAKEG 271 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 + +KG G I++ V A VL Sbjct: 272 VKSLFKGAGANILRGVAGAGVL 293 Score = 38.5 bits (88), Expect = 0.019 Identities = 40/175 (22%), Positives = 72/175 (41%), Gaps = 7/175 (4%) Frame = -3 Query: 638 RLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQ 459 R +LD R G I + + G+ W+G +I ++ + L+ + Sbjct: 49 RAGRLDR---RYNGIIDCFKRTTADEGVMALWRGNTANVI-------RYFPTQALNFAFR 98 Query: 458 SKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS----- 294 K KK++ ++ G +A GA T LL V S A+ + +A S Sbjct: 99 DKFKKMFGYKKDVDGYWKWMAGNLASGGAAGAT-SLLFVYSLDYARTRLANDAKSAKKGG 157 Query: 293 --RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILL 135 ++ G +D K I +G+ G Y+G G + V + F + + +K V+L+ Sbjct: 158 ERQFNGLVDVYRKTIASDGIAGLYRGFGPSVAGIVVYRGLYFGLYDS-IKPVLLV 211
>MFRN_DROME (Q9VAY3) Mitoferrin| Length = 379 Score = 48.9 bits (115), Expect = 1e-05 Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 2/170 (1%) Frame = -3 Query: 665 SMDAHILKDRLAKLDSEKPRPY-GTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQF 492 S ++K R+ +S PY + +R++Y+ G F++ L+M + +I F Sbjct: 125 SSPTDVIKQRMQMYNS----PYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHF 180 Query: 491 MIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 YE ++ +R K P ++ A GA A A VT PL V+K+ L QE Sbjct: 181 TTYEFFQNKMNLER--KYNPPVHMAA------GAAAGACAAAVTTPLDVIKTLLNT-QET 231 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 G G ++A K+ G GF++G +++ S+ A ++ + E Sbjct: 232 GLT-----RGMIEASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYE 276 Score = 38.5 bits (88), Expect = 0.019 Identities = 29/114 (25%), Positives = 52/114 (45%) Frame = -3 Query: 503 SIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA 324 S+ F YE ++K L +K + R + + GA+A L ++ P V+K R+Q Sbjct: 86 SLYFAAYE-MTKELTAKFTSVR-------NLNYVISGAVATLIHDAISSPTDVIKQRMQM 137 Query: 323 KQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 S YT + + + + EG FY+ GT++V ++ ++ F E Sbjct: 138 YN-------SPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYE 184 Score = 29.6 bits (65), Expect = 8.8 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GAIA + VV YPL VK+R+Q+ +N + + MI EGL +G Sbjct: 21 GAIAGVLEHVVMYPLDSVKTRMQSLSPPTKN-----MNIVSTLRTMITREGLLRPIRGAS 75 Query: 215 TKIVQSVFAASVLF----MVKEELVKF 147 ++ + A S+ F M KE KF Sbjct: 76 AVVLGAGPAHSLYFAAYEMTKELTAKF 102
>ADT2_WHEAT (Q41630) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 331 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/142 (23%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + R+ + GI+G ++G I + ++ + F +Y++L L + Sbjct: 181 GLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSLKPVLLTGTL-------Q 233 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + + F LG + GA + +YP+ V+ R+ A +Y +LDA ++ EG Sbjct: 234 VCSFASFALGWLITNGAGLASYPIDTVRRRMMMTS----GEAVKYKSSLDAFQQIPAKEG 289 Query: 242 LHGFYKGMGTKIVQSVFAASVL 177 +KG G I++++ A VL Sbjct: 290 AKSLFKGAGANILRAIAGAGVL 311
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier| Length = 327 Score = 48.9 bits (115), Expect = 1e-05 Identities = 36/144 (25%), Positives = 70/144 (48%), Gaps = 3/144 (2%) Frame = -3 Query: 593 IQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN--I 420 IQA + + +E GI+ +KG + TL S + +SK + R ++ K+ + Sbjct: 178 IQAAKTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPV 237 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKM-IRYEG 243 + V L G IA + + +P+ +K++LQ A+S L A ++ ++ G Sbjct: 238 NILNVCLAGGIAGMSMWLAVFPIDTIKTKLQ--------ASSTRQNMLSATKEIYLQRGG 289 Query: 242 LHGFYKGMGTKIVQSVFAASVLFM 171 + GF+ G+G +++S A + F+ Sbjct: 290 IKGFFPGLGPALLRSFPANAATFL 313 Score = 32.3 bits (72), Expect = 1.4 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 13/120 (10%) Frame = -3 Query: 635 LAKLDSEKPRPYGTIQAIREVYRES-----------GISGFWKGLIPTLIMVCNP--SIQ 495 L K+ + + T+ AI + +E+ + GF+KG+IP L+ V P ++ Sbjct: 58 LIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVKGFYKGVIPPLLGV-TPIFAVS 116 Query: 494 FMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE 315 F Y+ + K+L + + K+ +T ++ G I+ + T+VT P VK LQ + Sbjct: 117 FWGYD-VGKKLVT-FNNKQGGSNELTMGQMAAAGFISAIPTTLVTAPTERVKVVLQTSSK 174
>ADT1_RAT (Q05962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) Length = 297 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/154 (23%), Positives = 74/154 (48%), Gaps = 2/154 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + ++++ G+ G ++G + ++ + F +Y+T L KN Sbjct: 155 GLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDP--------KN 206 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYE 246 + + +++ A +V+YP V+ R+ + GR A YTGT+D K+ + E Sbjct: 207 VHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIAKDE 264 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G F+KG + +++ + A VL ++ +E+ K+V Sbjct: 265 GRKAFFKGAWSNVLRGMGGAFVL-VLYDEIKKYV 297 Score = 39.7 bits (91), Expect = 0.009 Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 8/152 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKR--LQSKRSGKRFPKK 426 G I + + +E G FW+G + +I ++ K+ L K+F + Sbjct: 52 GIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWR- 110 Query: 425 NITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR-YTGTLDAIL 264 + G +A GA T YPL ++RL A ++G+ ++ R + G D + Sbjct: 111 -------YFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DVGKGSSQREFNGLGDCLT 161 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 168 K+ + +GL G Y+G + + + F V Sbjct: 162 KIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGV 193
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor| Length = 329 Score = 48.5 bits (114), Expect = 2e-05 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Frame = -3 Query: 551 GFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLG 375 G +GL PT+I + F++YE L R G + I ++ L GA + Sbjct: 197 GLMRGLFPTMIRAGHGLGTYFLVYEALVAR----EIGTGLTRNEIPPWKLCLFGAFSGTM 252 Query: 374 ATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI-RYEGLHGFYKGMGTKIVQS 198 + YPL VVKS +Q ++ + +Y ++ + K I EG+ F+KG G +V+S Sbjct: 253 LWLTVYPLDVVKSIIQ-NDDLRK---PKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRS 308 Query: 197 VFAASVLFMVKEELVKFV 144 F+ E +++F+ Sbjct: 309 APVNGATFLTFELVMRFL 326 Score = 39.7 bits (91), Expect = 0.009 Identities = 29/99 (29%), Positives = 44/99 (44%) Frame = -3 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 KR N ++F G I + +V P K RLQ A+ T TL+ + Sbjct: 26 KRELSSNRVLKDIFA-GTIGGIAQVLVGQPFDTTKVRLQT--------ATTRTTTLEVLR 76 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 +++ EG+ FYKG T ++ SV F V E + +F Sbjct: 77 NLVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAMKRF 115
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 48.1 bits (113), Expect = 2e-05 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 2/146 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++Y+ GI G ++G N S+Q +IY + G KN + Sbjct: 162 KIYKSDGIRGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGAKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKEELVKF 147 G + +++ + A VL ++ +E+ KF Sbjct: 272 GAWSNVLRGMGGAFVL-VLYDEIKKF 296
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1| Length = 310 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 8/85 (9%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI--------GRNAASRYTGTLDAILKMIRY 249 F GAIA + +V YPL VVK+R+Q + + A YTG +D + K+++ Sbjct: 15 FTAGAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKK 74 Query: 248 EGLHGFYKGMGTKIVQSVFAASVLF 174 EG YKG+ + I+ ++ F Sbjct: 75 EGFSHLYKGITSPILMEAPKRAIKF 99
>UCP1_HUMAN (P25874) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 47.8 bits (112), Expect = 3e-05 Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 7/172 (4%) Frame = -3 Query: 650 ILKDRL---AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIY 483 ++K RL + L KPR GT A R + G++G WKG P L+ V + + Y Sbjct: 136 VVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTY 195 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 + + + F K NI A +V + IA AT ++ P+ VVK+R Sbjct: 196 DLMK---------EAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVKTRFI----- 241 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 + +Y + +K+ EG F+KG+ ++ ++F+ E+L Sbjct: 242 -NSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQL 292 Score = 43.9 bits (102), Expect = 5e-04 Identities = 26/90 (28%), Positives = 48/90 (53%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 +++F G A L A V+T+PL K RLQ + E ++ RY G L I +++ EG Sbjct: 15 VQLFSAGIAACL-ADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMK 73 Query: 233 FYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 Y G+ + + + +AS+ + + + +F+ Sbjct: 74 LYSGLPAGLQRQISSASLRIGLYDTVQEFL 103
>M2OM_BOVIN (P22292) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/69 (37%), Positives = 41/69 (59%), Gaps = 1/69 (1%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 228 FL G +A +GATV PL +VK+R+Q G A +R Y + A++ ++R EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVKNRMQLS---GEGAKTREYKTSFHALISILRAEGLRGIY 80 Query: 227 KGMGTKIVQ 201 G+ +++ Sbjct: 81 TGLSAGLLR 89 Score = 47.4 bits (111), Expect = 4e-05 Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 5/141 (3%) Frame = -3 Query: 629 KLDSEKPRPYGTI-QAIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQ 459 +L ++ R Y + A+ + +E G+ W+G IPT+ +V N + L+ Q Sbjct: 151 RLPVDQRRGYKNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAA-------QLASYSQ 203 Query: 458 SKRS--GKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYT 285 SK+ + NI F I+ L T + P+ +VK+R+Q + I + Y Sbjct: 204 SKQFLLDSGYFSDNILCH--FCASMISGLVTTAASMPVDIVKTRIQNMRMI--DGKPEYK 259 Query: 284 GTLDAILKMIRYEGLHGFYKG 222 LD ++K++RYEG +KG Sbjct: 260 NGLDVLVKVVRYEGFFSLWKG 280
>CMC1_CAEEL (Q21153) Probable calcium-binding mitochondrial carrier K02F3.2| Length = 707 Score = 47.4 bits (111), Expect = 4e-05 Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 1/68 (1%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFY 228 FLLG++A YP+ +VK+R+Q ++ G Y +LD K++++EGL G Y Sbjct: 373 FLLGSVAGACGATAVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLY 432 Query: 227 KGMGTKIV 204 +G+ +IV Sbjct: 433 RGLLPQIV 440 Score = 39.3 bits (90), Expect = 0.011 Identities = 37/152 (24%), Positives = 60/152 (39%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLL 396 V +E G G +KG + S + +K + G P +F Sbjct: 514 VLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAHAKLASADEDGMNSPGT------LFAS 567 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 IA + A + P V+K+RLQ G+ Y G +D K+I+ EG +KG Sbjct: 568 AFIAGVPAAGLVTPADVIKTRLQVAARAGQTT---YNGVIDCARKLIKEEGPMSLWKGTA 624 Query: 215 TKIVQSVFAASVLFMVKEELVKFVILLVARSR 120 ++ +S +V + E L + + A SR Sbjct: 625 ARVCRSSPQFAVTLLTYEVLQRLFYVDFAGSR 656 Score = 36.2 bits (82), Expect = 0.094 Identities = 31/143 (21%), Positives = 62/143 (43%), Gaps = 2/143 (1%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSK--RSGKRFPKKN 423 ++ ++V + G+ G ++GL+P ++ V I T++ ++ K + GK Sbjct: 415 SLDCFKKVVKFEGLLGLYRGLLPQIVGVAPEKA---IKLTMNDYMRDKFTKDGK------ 465 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 I + G + V T PL +VK RLQ E+ + G + +++ G Sbjct: 466 IPLYGEIIAGGTGGMCQVVFTNPLEIVKIRLQTAGEV------QQAGKKIGVFTVLKELG 519 Query: 242 LHGFYKGMGTKIVQSVFAASVLF 174 G YKG ++ + +++ F Sbjct: 520 FLGLYKGSRACFLRDIPFSAIYF 542
>ADT2_ANOGA (Q7PQV7) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 300 Score = 47.4 bits (111), Expect = 4e-05 Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 6/149 (4%) Frame = -3 Query: 635 LAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQS 456 ++K +E R G + + RE G S FW+G + +I ++ K++ Sbjct: 43 ISKQIAEADRYKGMVDCFVRIPREQGFSAFWRGNLANVIRYFPTQALNFAFKDKYKQVFL 102 Query: 455 KRSGKRFPKKNITAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASR 291 K T + +G +A G T YPL ++RL A ++G+ A +R Sbjct: 103 GGVDKN------TQFTRYFIGNLASGGMAGATSLCFVYPLDFARTRLAA--DVGKGAEAR 154 Query: 290 -YTGTLDAILKMIRYEGLHGFYKGMGTKI 207 + G D I K+ + +GL G Y+G G + Sbjct: 155 EFKGLGDCISKIFKTDGLVGLYRGFGVSV 183 Score = 35.0 bits (79), Expect = 0.21 Identities = 33/152 (21%), Positives = 63/152 (41%), Gaps = 6/152 (3%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G I ++++ G+ G ++G + ++ + F Y+T L + ++ + Sbjct: 158 GLGDCISKIFKTDGLVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPNPKTTPWYVSWA 217 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRL-----QAKQEIGRNAASRYTGTLDAILKM 258 I + G +V+YP V+ R+ +AK EI Y GTL + Sbjct: 218 IAQCVTTVAG--------IVSYPFDTVRRRMMMQSGRAKSEIV------YKGTLHCWATI 263 Query: 257 IRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 + EG F+KG + +++ A VL + E Sbjct: 264 AKQEGTGAFFKGAFSNVLRGTGGAFVLVLYDE 295
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++Y+ GI G ++G N S+Q +IY + G KN + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGSKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++Y+ GI G ++G N S+Q +IY + G KN + + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGGKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>M2OM_HUMAN (Q02978) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 47.4 bits (111), Expect = 4e-05 Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 5/141 (3%) Frame = -3 Query: 629 KLDSEKPRPYGTI-QAIREVYRESGISGFWKGLIPTLI--MVCNPSIQFMIYETLSKRLQ 459 +L +++ R Y + A+ + RE G+ W+G IPT+ +V N + L+ Q Sbjct: 151 RLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAA-------QLASYSQ 203 Query: 458 SKRS--GKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYT 285 SK+ + NI F I+ L T + P+ + K+R+Q + I + Y Sbjct: 204 SKQFLLDSGYFSDNILCH--FCASMISGLVTTAASMPVDIAKTRIQNMRMI--DGKPEYK 259 Query: 284 GTLDAILKMIRYEGLHGFYKG 222 LD + K++RYEG +KG Sbjct: 260 NGLDVLFKVVRYEGFFSLWKG 280 Score = 45.4 bits (106), Expect = 2e-04 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASR-YTGTLDAILKMIRYEGLHGFY 228 FL G +A +GATV PL +VK+R+Q G A +R Y + A+ +++ EGL G Y Sbjct: 24 FLFGGLAGMGATVFVQPLDLVKNRMQLS---GEGAKTREYKTSFHALTSILKAEGLRGIY 80 Query: 227 KGMGTKIVQ 201 G+ +++ Sbjct: 81 TGLSAGLLR 89
>CMC1_PONPY (Q5RBC8) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/127 (27%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 399 V R+ GI G +KG + + +I F +Y K L + +G ++ + + Sbjct: 471 VLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHC-KLLLADENG------HVGGLNLLA 523 Query: 398 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 219 GA+A + A + P V+K+RLQ G+ Y+G +D K++R EG F+KG Sbjct: 524 AGAMAGVPAASLVTPADVIKTRLQVAARAGQTT---YSGVIDCFRKILREEGPSAFWKGT 580 Query: 218 GTKIVQS 198 ++ +S Sbjct: 581 AARVFRS 587 Score = 44.7 bits (104), Expect = 3e-04 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 1/144 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 + ++V R G G ++GLIP LI V +I+ + + + + + P + Sbjct: 372 SFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAE-- 429 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 L G A + T PL +VK RLQ EI TG + L ++R G+ Sbjct: 430 -----VLAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALNVLRDLGI 477 Query: 239 HGFYKGMGTKIVQSVFAASVLFMV 168 G YKG ++ + +++ F V Sbjct: 478 FGLYKGAKACFLRDIPFSAIYFPV 501 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Frame = -3 Query: 404 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 231 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 330 FTLGSVAGAVGATAV-YPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388 Query: 230 YKGMGTKIV 204 Y+G+ +++ Sbjct: 389 YRGLIPQLI 397
>CMC1_HUMAN (O75746) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/127 (27%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 399 V R+ GI G +KG + + +I F +Y K L + +G ++ + + Sbjct: 471 VLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHC-KLLLADENG------HVGGLNLLA 523 Query: 398 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 219 GA+A + A + P V+K+RLQ G+ Y+G +D K++R EG F+KG Sbjct: 524 AGAMAGVPAASLVTPADVIKTRLQVAARAGQTT---YSGVIDCFRKILREEGPSAFWKGT 580 Query: 218 GTKIVQS 198 ++ +S Sbjct: 581 AARVFRS 587 Score = 44.7 bits (104), Expect = 3e-04 Identities = 37/144 (25%), Positives = 62/144 (43%), Gaps = 1/144 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 + ++V R G G ++GLIP LI V +I+ + + + + + P + Sbjct: 372 SFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAE-- 429 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 L G A + T PL +VK RLQ EI TG + L ++R G+ Sbjct: 430 -----VLAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALNVLRDLGI 477 Query: 239 HGFYKGMGTKIVQSVFAASVLFMV 168 G YKG ++ + +++ F V Sbjct: 478 FGLYKGAKACFLRDIPFSAIYFPV 501 Score = 44.3 bits (103), Expect = 3e-04 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Frame = -3 Query: 404 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 231 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 330 FTLGSVAGAVGATAV-YPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGL 388 Query: 230 YKGMGTKIV 204 Y+G+ +++ Sbjct: 389 YRGLIPQLI 397
>ORNT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 46.6 bits (109), Expect = 7e-05 Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 2/143 (1%) Frame = -3 Query: 584 IREVYRESGISGFWKGLIPTLIMVCNPSIQFMI--YETLSKRLQSKRSGKRFPKKNITAM 411 I+ + R+ G GF+ GL TL+ P F YE S RS K + + Sbjct: 157 IKSILRKDGPLGFYHGLSSTLLREV-PGYFFFFGGYELSRSFFASGRS-----KDELGPV 210 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 + L G + + + YP+ +KSR+Q G+ A G + + +++ EG+ Sbjct: 211 PLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQA-----GFIRTFINVVKNEGITAL 265 Query: 230 YKGMGTKIVQSVFAASVLFMVKE 162 Y G+ ++++ A LF+ E Sbjct: 266 YSGLKPTMIRAFPANGALFLAYE 288 Score = 35.0 bits (79), Expect = 0.21 Identities = 21/75 (28%), Positives = 31/75 (41%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA + P +K ++Q ++ Y G D LK G GFYKG Sbjct: 16 GAAGGTACVLTGQPFDTMKVKMQTFPDL-------YRGLTDCCLKTYSQVGFRGFYKGTS 68 Query: 215 TKIVQSVFAASVLFM 171 ++ ++ SVLFM Sbjct: 69 PALIANIAENSVLFM 83
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 46.6 bits (109), Expect = 7e-05 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++Y+ GI G ++G N S+Q +IY + G KN + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGGKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>UCP2_CYPCA (Q9W725) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 46.2 bits (108), Expect = 9e-05 Identities = 40/155 (25%), Positives = 69/155 (44%), Gaps = 1/155 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 62 GVFGTISTMVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 114 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + + G A + P VVK R QA+ G N RY GT+DA + + EG Sbjct: 115 VGIGSRLMAGCTTGAMAVALAQPTDVVKVRFQAQNSAGAN--KRYHGTMDAYRTIAKEEG 172 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 G +KG G I ++ + +V +L+K +L Sbjct: 173 FRGLWKGTGPNITRNAI-VNCTELVTYDLIKDALL 206 Score = 45.1 bits (105), Expect = 2e-04 Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 5/156 (3%) Frame = -3 Query: 608 RPYGTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSG 444 R +GT+ A R + +E G G WKG P + I+ C + + +I + L L+S Sbjct: 156 RYHGTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVNCTELVTYDLIKDAL---LKSSLMT 212 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 P +A A TV+ P+ VVK+R +A +Y L+ + Sbjct: 213 DDLPCHFTSAFG-------AGFCTTVIASPVDVVKTRYM------NSAPGQYCSALNCAV 259 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 M+ EG FYKG ++ V+F+ E+L Sbjct: 260 AMLTKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQL 295 Score = 33.9 bits (76), Expect = 0.47 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 5/96 (5%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE--IGRNAAS---RYTGTLDAILKMI 255 TA F+ A A + T+PL K RLQ + E I N +Y G I M+ Sbjct: 12 TATVKFIGAGTAACIADLFTFPLDTAKVRLQIQGESKIPVNTGHGPVKYRGVFGTISTMV 71 Query: 254 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 R EG Y G+ + + + ASV + + + +F Sbjct: 72 RVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQF 107
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 675 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/144 (25%), Positives = 63/144 (43%), Gaps = 1/144 (0%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 399 V R+ G G +KG + + +I F Y + ++ ++ + L Sbjct: 473 VVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG-------QVSPGSLLL 525 Query: 398 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 219 GAIA + A + P V+K+RLQ G+ Y+G +D K++R EG +KG Sbjct: 526 AGAIAGMPAASLVTPADVIKTRLQVAARAGQTT---YSGVIDCFRKILREEGPKALWKGA 582 Query: 218 GTKIVQSVFAASVLFMVKEELVKF 147 G ++ +S V + E L ++ Sbjct: 583 GARVFRSSPQFGVTLLTYELLQRW 606 Score = 43.9 bits (102), Expect = 5e-04 Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Frame = -3 Query: 404 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 231 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 332 FGLGSVAGAVGATAV-YPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390 Query: 230 YKGM 219 Y+G+ Sbjct: 391 YRGL 394 Score = 42.0 bits (97), Expect = 0.002 Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 1/142 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 + ++V R G G ++GL+P L+ V +I+ + + + + K ++ Sbjct: 374 SFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG-------SV 426 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 L G A + T PL +VK RLQ EI TG + L ++R G Sbjct: 427 PLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALSVVRDLGF 479 Query: 239 HGFYKGMGTKIVQSVFAASVLF 174 G YKG ++ + +++ F Sbjct: 480 FGIYKGAKACFLRDIPFSAIYF 501
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor| Length = 307 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/151 (26%), Positives = 72/151 (47%), Gaps = 5/151 (3%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNP-SIQFMIYETLSKRLQSKRSGKRFPKKN 423 G ++ I+++ + +GL PT++ + F++YE L +KR G +K+ Sbjct: 162 GPLECIKKLRHNKALL---RGLTPTILREGHGCGTYFLVYEALIANQMNKRRG--LERKD 216 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA----KQEIGRNAASRYTGTLDAILKMI 255 I A ++ + GA++ ++ YPL V+KS +Q K + G N+ S TL A Sbjct: 217 IPAWKLCIFGALSGTALWLMVYPLDVIKSVMQTDNLQKPKFG-NSISSVAKTLYA----- 270 Query: 254 RYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 G+ F+KG G ++++ A F E Sbjct: 271 -NGGIGAFFKGFGPTMLRAAPANGATFATFE 300 Score = 36.6 bits (83), Expect = 0.072 Identities = 25/93 (26%), Positives = 40/93 (43%) Frame = -3 Query: 425 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 N ++ L G + +V P K RLQ +S T ++ + K++ E Sbjct: 22 NARVVKDLLAGTAGGIAQVLVGQPFDTTKVRLQT--------SSTPTTAMEVVRKLLANE 73 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 G GFYKG T ++ S+ F V E + +F Sbjct: 74 GPRGFYKGTLTPLIGVGACVSLQFGVNEAMKRF 106
>UCP1_BOVIN (P10861) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) (Fragment) Length = 288 Score = 45.8 bits (107), Expect = 1e-04 Identities = 47/178 (26%), Positives = 82/178 (46%), Gaps = 11/178 (6%) Frame = -3 Query: 650 ILKDRL---AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 ++K RL + L KPR GT A R + G++G WKG P L V + + Y Sbjct: 118 VVKVRLQAQSHLHGPKPRYTGTYNAYRIIATTEGLTGLWKGTSPNLTTNVIINCTELVTY 177 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 + + + L K + A +V F+ +A TV++ P+ VVK+R Sbjct: 178 DLMKEAL---------VKNKLLADDVPCHFVSAVVAGFCTTVLSSPVDVVKTRF-VNSSP 227 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFM----VKEELVK 150 G+N T + + M+ EG F+KG ++ + + +++F+ +K+EL+K Sbjct: 228 GQN-----TSVPNCAMMMLTREGPSAFFKGFVPSFLR-LGSWNIMFVCFERLKQELMK 279 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/81 (28%), Positives = 42/81 (51%) Frame = -3 Query: 389 IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTK 210 +A A ++T+PL K RLQ + E ++A RY G L I+ + + EG Y G+ Sbjct: 6 VAACVADIITFPLDTAKVRLQIQGECLISSAIRYKGVLGTIITLAKTEGPVKLYSGLPAG 65 Query: 209 IVQSVFAASVLFMVKEELVKF 147 + + + AS+ + + + +F Sbjct: 66 LQRQISLASLRIGLYDTVQEF 86
>ADT3_HUMAN (P12236) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) Length = 297 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 2/141 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGL-IPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++ + GI G ++G + ++ + F +Y+T L KN + + Sbjct: 162 KITKSDGIRGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDP--------KNTHIVVSW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A VV+YP V+ R+ + GR A YTGT+D K+ R EG F+K Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQS--GRKGADIMYTGTVDCWRKIFRDEGGKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 45.8 bits (107), Expect = 1e-04 Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++Y+ GI G ++G N S+Q +IY + G KN + + Sbjct: 162 KIYKSDGIKGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A + +YP V+ R+ + GR YTGTLD K+ R EG F+K Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQS--GRKGTDIMYTGTLDCWRKIARDEGGKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G + +++ + A L + E Sbjct: 272 GAWSNVLRGMGGAFALVLYDE 292
>CMC1_MOUSE (Q8BH59) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 677 Score = 45.4 bits (106), Expect = 2e-04 Identities = 39/143 (27%), Positives = 60/143 (41%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 417 + ++V R G G ++GLIP LI V + + +KR G +I Sbjct: 372 SFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTKRDG------SIP 425 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 237 L G A + T PL +VK RLQ EI TG + L +++ GL Sbjct: 426 LPAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALNVLQDLGLF 478 Query: 236 GFYKGMGTKIVQSVFAASVLFMV 168 G YKG ++ + +++ F V Sbjct: 479 GLYKGAKACFLRDIPFSAIYFPV 501 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 1/127 (0%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 399 V ++ G+ G +KG + + +I F +Y K L + +G+ + + + Sbjct: 471 VLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHC-KLLLADENGR------VGGINLLT 523 Query: 398 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 219 GA+A + A + P V+K+RLQ G+ Y+G +D K++R EG F+KG Sbjct: 524 AGALAGVPAASLVTPADVIKTRLQVAARAGQTT---YSGVVDCFRKILREEGPSAFWKGT 580 Query: 218 GTKIVQS 198 ++ +S Sbjct: 581 AARVFRS 587 Score = 44.7 bits (104), Expect = 3e-04 Identities = 25/69 (36%), Positives = 42/69 (60%), Gaps = 2/69 (2%) Frame = -3 Query: 404 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 231 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 330 FTLGSVAGAVGATAV-YPIDLVKTRMQNQRGTGSVVGELMYKNSFDCFKKVLRYEGFFGL 388 Query: 230 YKGMGTKIV 204 Y+G+ +++ Sbjct: 389 YRGLIPQLI 397
>UCP2_RAT (P56500) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 45.4 bits (106), Expect = 2e-04 Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 8/159 (5%) Frame = -3 Query: 608 RPYGTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSG 444 R T++A + + RE GI G WKG P + I+ C + + +I +TL K Sbjct: 155 RYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCTELVTYDLIKDTLLKA------- 207 Query: 443 KRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 273 N+ ++ F A TV+ P+ VVK+R +A +Y Sbjct: 208 ------NLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYM------NSALGQYHSAGH 255 Query: 272 AILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 L M+R EG FYKG ++ V+F+ E+L Sbjct: 256 CALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQL 294 Score = 45.4 bits (106), Expect = 2e-04 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE---IGRNAAS-RYTGTLDAILKMIR 252 TA FL A A ++T+PL K RLQ + E + R AAS +Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVR 71 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106 Score = 40.0 bits (92), Expect = 0.007 Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 61 GVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 113 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 L G+ A V P VVK R QA+ G RY T++A + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--GGRRYQSTVEAYKTIAREEG 171 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 + G +KG + ++ + +V +L+K +L Sbjct: 172 IRGLWKGTSPNVARNAI-VNCTELVTYDLIKDTLL 205
>CG69_HUMAN (Q9BZJ4) Mitochondrial carrier protein CGI-69| Length = 359 Score = 45.1 bits (105), Expect = 2e-04 Identities = 42/163 (25%), Positives = 68/163 (41%) Frame = -3 Query: 638 RLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQ 459 R A + R GT+ A ++ R G W GL TL+M + IY T +L+ Sbjct: 93 RCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATA---IYFTAYDQLK 149 Query: 458 SKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGT 279 + G+ M + GA+A+LG V PL +++++LQA+ R + Sbjct: 150 AFLCGRALTSDLYAPM---VAGALARLGTVTVISPLELMRTKLQAQHVSYRELGA----- 201 Query: 278 LDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 + + G + G G ++ V S L+ ELVK Sbjct: 202 --CVRTAVAQGGWRSLWLGWGPTALRDV-PFSALYWFNYELVK 241 Score = 42.4 bits (98), Expect = 0.001 Identities = 17/51 (33%), Positives = 33/51 (64%) Frame = -3 Query: 296 SRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 +R+TGT+DA +K++R+EG + G+ +V +V A ++ F ++L F+ Sbjct: 102 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
>UCP2_MOUSE (P70406) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 45.1 bits (105), Expect = 2e-04 Identities = 46/171 (26%), Positives = 73/171 (42%), Gaps = 8/171 (4%) Frame = -3 Query: 608 RPYGTIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSG 444 R T++A + + RE GI G WKG P + I+ C + + +I +TL K Sbjct: 155 RYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLLKA------- 207 Query: 443 KRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 273 N+ ++ F A TV+ P+ VVK+R +A +Y Sbjct: 208 ------NLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYM------NSALGQYHSAGH 255 Query: 272 AILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARSR 120 L M+R EG FYKG ++ V+F+ E+L K ++ +SR Sbjct: 256 CALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQL-KRALMAAYQSR 305 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE---IGRNAAS-RYTGTLDAILKMIR 252 TA FL A A ++T+PL K RLQ + E + R AAS +Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVR 71 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106 Score = 40.0 bits (92), Expect = 0.007 Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 61 GVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 113 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 L G+ A V P VVK R QA+ G RY T++A + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--GGRRYQSTVEAYKTIAREEG 171 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 + G +KG + ++ + +V +L+K +L Sbjct: 172 IRGLWKGTSPNVARNAI-VNCAELVTYDLIKDTLL 205
>ADT3_BOVIN (P32007) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) (ANT 2) Length = 297 Score = 44.7 bits (104), Expect = 3e-04 Identities = 36/141 (25%), Positives = 63/141 (44%), Gaps = 2/141 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++ + GI G ++G N S+Q +IY + G KN + + Sbjct: 162 KITKSDGIRGLYQGF--------NVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVVSW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A VV+YP V+ R+ + GR A Y GT+D K+++ EG F+K Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQS--GRKGADIMYKGTVDCWRKILKDEGGKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>CMC2_MOUSE (Q9QXX4) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 676 Score = 44.3 bits (103), Expect = 3e-04 Identities = 26/64 (40%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Frame = -3 Query: 404 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 231 F LG+IA +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 333 FGLGSIAGAVGATAV-YPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 391 Query: 230 YKGM 219 Y+G+ Sbjct: 392 YRGL 395 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 1/144 (0%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFL 399 V R+ G G +KG + + +I F Y + ++ ++ + L Sbjct: 474 VVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG-------QVSPGSLLL 526 Query: 398 LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGM 219 GAIA + A + P V+K+RLQ G+ Y G D K++R EG +KG+ Sbjct: 527 AGAIAGMPAASLVTPADVIKTRLQVAARAGQTT---YNGVTDCFRKILREEGPKALWKGV 583 Query: 218 GTKIVQSVFAASVLFMVKEELVKF 147 ++ +S V + E L ++ Sbjct: 584 AARVFRSSPQFGVTLLTYELLQRW 607 Score = 41.6 bits (96), Expect = 0.002 Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 1/142 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 + ++V R G G ++GL+P L+ V +I+ + + + + K ++ Sbjct: 375 SFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG-------SV 427 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 + G A + T PL +VK RLQ EI TG + L ++R G Sbjct: 428 PLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALSVVRDLGF 480 Query: 239 HGFYKGMGTKIVQSVFAASVLF 174 G YKG ++ + +++ F Sbjct: 481 FGIYKGAKACFLRDIPFSAIYF 502
>DIC_HUMAN (Q9UBX3) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 44.3 bits (103), Expect = 3e-04 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 1/144 (0%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETL 474 +LK L K R G A+R V R GI + GL +L S+ +F IYET+ Sbjct: 29 LLKVHLQTQQEVKLRMTG--MALR-VVRTDGILALYSGLSASLCRQMTYSLTRFAIYETV 85 Query: 473 SKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS 294 R+ G + E LLG+++ L V P +V R+Q ++ + Sbjct: 86 RDRVAKGSQGP------LPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRR 139 Query: 293 RYTGTLDAILKMIRYEGLHGFYKG 222 Y LD + ++ R EGL + G Sbjct: 140 NYAHALDGLYRVAREEGLRRLFSG 163 Score = 37.0 bits (84), Expect = 0.055 Identities = 22/78 (28%), Positives = 39/78 (50%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 G +A GA T+PL ++K LQ +QE+ R TG L+++R +G+ Y G+ Sbjct: 13 GGLASCGAACCTHPLDLLKVHLQTQQEV----KLRMTG---MALRVVRTDGILALYSGLS 65 Query: 215 TKIVQSVFAASVLFMVKE 162 + + + + F + E Sbjct: 66 ASLCRQMTYSLTRFAIYE 83
>UCP2_HUMAN (P55851) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 43.9 bits (102), Expect = 5e-04 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE----IGRNAASRYTGTLDAILKMIR 252 TA FL A A ++T+PL K RLQ + E + A+++Y G + IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVR 71 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQF 106
>MFRN1_HUMAN (Q9NYZ2) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 347 Score = 43.9 bits (102), Expect = 5e-04 Identities = 45/169 (26%), Positives = 75/169 (44%), Gaps = 5/169 (2%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQ-AIREVYRESGISGFWKGL--IPTLIMVCNPS--IQFMIY 483 +K R+ L + Y +I A++++ R G FW+ L + +IM P+ + F Y Sbjct: 69 VKTRMQSLSPDPKAQYTSIYGALKKIMRTEG---FWRPLRGVNVMIMGAGPAHAMYFACY 125 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRN 303 E + + L F + + + + G++A L V P VVK RLQ R+ Sbjct: 126 ENMKRTLNDV-----FHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRS 180 Query: 302 AASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 A S I + R EGL FY+ T++ ++ S+ F+ E L Sbjct: 181 AIS-------CIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 222 Score = 31.6 bits (70), Expect = 2.3 Identities = 22/80 (27%), Positives = 42/80 (52%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA+A + V YP+ VK+R+Q+ + + ++YT A+ K++R EG +G+ Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQS---LSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108 Query: 215 TKIVQSVFAASVLFMVKEEL 156 I+ + A ++ F E + Sbjct: 109 VMIMGAGPAHAMYFACYENM 128
>CMC2_MACFA (Q8HXW2) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 674 Score = 43.9 bits (102), Expect = 5e-04 Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 2/64 (3%) Frame = -3 Query: 404 FLLGAIA-KLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGF 231 F LG++A +GAT V YP+ +VK+R+Q ++ G Y + D K++RYEG G Sbjct: 332 FGLGSVAGAVGATAV-YPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGL 390 Query: 230 YKGM 219 Y+G+ Sbjct: 391 YRGL 394 Score = 42.0 bits (97), Expect = 0.002 Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 1/142 (0%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTLIMVC-NPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 + ++V R G G ++GL+P L+ V +I+ + + + + K ++ Sbjct: 374 SFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDG-------SV 426 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 L G A + T PL +VK RLQ EI TG + L ++R G Sbjct: 427 PLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEI-------TTGPRVSALSVVRDLGF 479 Query: 239 HGFYKGMGTKIVQSVFAASVLF 174 G YKG ++ + +++ F Sbjct: 480 FGIYKGAKACFLRDIPFSAIYF 501 Score = 39.7 bits (91), Expect = 0.009 Identities = 22/62 (35%), Positives = 34/62 (54%) Frame = -3 Query: 407 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 228 + L GAIA + A + P V+K+RLQ G+ + Y+G +D K++R EG + Sbjct: 523 LLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQ---TTYSGVIDCFKKILREEGPKALW 579 Query: 227 KG 222 KG Sbjct: 580 KG 581
>GDC_HUMAN (P16260) Grave disease carrier protein (GDC) (Grave disease| autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 43.9 bits (102), Expect = 5e-04 Identities = 43/180 (23%), Positives = 77/180 (42%), Gaps = 12/180 (6%) Frame = -3 Query: 650 ILKDRLAKLDSEKPRPYGTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYET 477 +++ RLA + R G I A + +Y +E G GF++GL+PT++ M + F + T Sbjct: 153 MVRVRLAFQVKGEHRYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGT 212 Query: 476 LS----KRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQ--- 327 L + N+ ++ L G +A+ A ++YP V + R+Q Sbjct: 213 LKSVGLSHAPTLLGSPSSDNPNVLVLKTHVNLLCGGVARAIAQTISYPFDVTRRRMQLGT 272 Query: 326 AKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 E + R T D IR G Y+G+ ++ + + +V F E + +F Sbjct: 273 VLPEFEKCLTMRDTMKYDYGHHGIR----KGLYRGLSLNYIRCIPSQAVAFTTYELMKQF 328
>MTCH2_PONPY (Q5R5M0) Mitochondrial carrier homolog 2| Length = 303 Score = 43.5 bits (101), Expect = 6e-04 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -3 Query: 560 GISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT---------AME 408 G G + GL P L C+ + +++ + + Q G+ N+ ++ Sbjct: 66 GRRGLFTGLTPRL---CSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIK 122 Query: 407 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 228 IA+ AT++T+P V+ R Q IGR S+Y G D+I+ + R EG+ GF+ Sbjct: 123 ETTREMIARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIITIYREEGILGFF 179 Query: 227 KGMGTKIVQSVFA 189 G+ +++ + + Sbjct: 180 AGLVPRLLGDILS 192 Score = 34.7 bits (78), Expect = 0.27 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 438 G +I +YRE GI GF+ GL+P L + +CN + L + + K Sbjct: 161 GLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKS 220 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 309 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>MTCH2_HUMAN (Q9Y6C9) Mitochondrial carrier homolog 2 (Met-induced mitochondrial| protein) Length = 303 Score = 43.5 bits (101), Expect = 6e-04 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 9/133 (6%) Frame = -3 Query: 560 GISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT---------AME 408 G G + GL P L C+ + +++ + + Q G+ N+ ++ Sbjct: 66 GRRGLFTGLTPRL---CSGVLGTVVHGKVLQHYQESDKGEELGPGNVQKEVSSSFDHVIK 122 Query: 407 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 228 IA+ AT++T+P V+ R Q IGR S+Y G D+I+ + R EG+ GF+ Sbjct: 123 ETTREMIARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIITIYREEGILGFF 179 Query: 227 KGMGTKIVQSVFA 189 G+ +++ + + Sbjct: 180 AGLVPRLLGDILS 192 Score = 34.7 bits (78), Expect = 0.27 Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 438 G +I +YRE GI GF+ GL+P L + +CN + L + + K Sbjct: 161 GLCDSIITIYREEGILGFFAGLVPRLLGDILSLWLCNSLAYLVNTYALDSGVSTMNEMKS 220 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 309 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>MRS4_YEAST (P23500) Mitochondrial RNA-splicing protein MRS4| Length = 304 Score = 43.5 bits (101), Expect = 6e-04 Identities = 42/169 (24%), Positives = 65/169 (38%), Gaps = 2/169 (1%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETL 474 LK R+ K G I I ++ G WKG + ++I+ P+ + F YE Sbjct: 47 LKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKG-VQSVILGAGPAHAVYFGTYEFC 105 Query: 473 SKRLQSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS 294 RL S + M+ L G IA + A + P VK RLQ + Sbjct: 106 KARLISPED-----MQTHQPMKTALSGTIATIAADALMNPFDTVKQRLQLDTNLR----- 155 Query: 293 RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 + ++ + EG FY T + ++ A+ FM+ E KF Sbjct: 156 ----VWNVTKQIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKF 200
>UCP2_PIG (O97562) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 43.1 bits (100), Expect = 8e-04 Identities = 43/163 (26%), Positives = 72/163 (44%), Gaps = 5/163 (3%) Frame = -3 Query: 596 TIQAIREVYRESGISGFWKGLIPTL----IMVCNPSIQF-MIYETLSKRLQSKRSGKRFP 432 T+ A + + RE G+ G WKG P + I+ C + + +I +TL L++ P Sbjct: 159 TVDAYKTIAREEGLRGLWKGTSPNVARNAIVNCAELVTYDLIKDTL---LKADLMTDDLP 215 Query: 431 KKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIR 252 +A A TV+ P+ VVK+R +A +Y+ L M++ Sbjct: 216 CHFTSAFG-------AGFCTTVIASPVDVVKTRYM------NSAPGQYSSAGHCALTMLQ 262 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVILLVARS 123 EG FYKG ++ V+F+ E+L + L+ AR+ Sbjct: 263 KEGPRAFYKGFTPSFLRLGSWNVVMFVTYEQLKR--ALMAARA 303 Score = 43.1 bits (100), Expect = 8e-04 Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 4/84 (4%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE----IGRNAASRYTGTLDAILKMIR 252 TA FL A A ++T+PL K RLQ + E + A+++Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGERRGPVQAAASAQYRGVLGTILTMVR 71 Query: 251 YEGLHGFYKGMGTKIVQSVFAASV 180 EG Y G+ + + + ASV Sbjct: 72 NEGPRSLYNGLVAGLQRQMSFASV 95 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + S++ +Y+++ K +K S ++ Sbjct: 61 GVLGTILTMVRNEGPRSLYNGLVAGLQRQMSFASVRIGLYDSV-KHFYTKGS------EH 113 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 L G+ A V P VVK R QA+ G RY T+DA + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--GGRRYRSTVDAYKTIAREEG 171 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 L G +KG + ++ + +V +L+K +L Sbjct: 172 LRGLWKGTSPNVARNAI-VNCAELVTYDLIKDTLL 205
>UCP2_CANFA (Q9N2J1) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 43.1 bits (100), Expect = 8e-04 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQE----IGRNAASRYTGTLDAILKMIR 252 TA FL A A ++T+PL K RLQ + E + A+++Y G L IL M+R Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGERQGPVRAAASAQYRGVLCTILTMVR 71 Query: 251 YEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 EG Y G+ + + + ASV + + + +F Sbjct: 72 TEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQF 106 Score = 40.8 bits (94), Expect = 0.004 Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G + I + R G + GL+ L + S++ +Y+++ K+ +K S ++ Sbjct: 61 GVLCTILTMVRTEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGS------EH 113 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 L G+ A V P VVK R QA+ G + RY T+DA + R EG Sbjct: 114 AGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAG--SGRRYQSTVDAYKTIAREEG 171 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 G +KG + ++ + +V +L+K +L Sbjct: 172 FRGLWKGTSPNVARNAI-VNCAELVTYDLIKDALL 205
>UCP1_PHOSU (Q9ER18) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 42.7 bits (99), Expect = 0.001 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 15 VKIFSAGVAACL-ADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGLPK 73 Query: 233 FYKGMGTKIVQSVFAASV 180 Y G+ I + + AS+ Sbjct: 74 LYSGLPAGIQRQISFASL 91 Score = 36.6 bits (83), Expect = 0.072 Identities = 42/174 (24%), Positives = 68/174 (39%), Gaps = 7/174 (4%) Frame = -3 Query: 650 ILKDRL---AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 ++K RL + L KPR GT A R + +S WKG P L+ V + + Y Sbjct: 136 VVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESLSTLWKGTTPNLLRNVIINCTELVTY 195 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 + + L + + I A +V L +A T + P VVK+R Sbjct: 196 DLMKGALVNNQ---------ILADDVPCHLLSALVAGFCTTFLASPADVVKTRFI----- 241 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 + +Y + M EG F+KG ++ ++F+ E+L K Sbjct: 242 -NSLPGQYPSVPSCAMTMFTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKK 294
>UCP1_RAT (P04633) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 14 VKIFSAGVSACL-ADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPK 72 Query: 233 FYKGMGTKIVQSVFAASV 180 Y G+ I + + AS+ Sbjct: 73 LYSGLPAGIQRQISFASL 90 Score = 37.0 bits (84), Expect = 0.055 Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 4/159 (2%) Frame = -3 Query: 614 KPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKR 438 KPR GT A R + +S WKG P L+ V + + Y+ + L + Sbjct: 150 KPRYTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVN------ 203 Query: 437 FPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 267 +I A +V L +A T++ P+ VVK+R + +Y Sbjct: 204 ---HHILADDVPCHLLSALVAGFCTTLLASPVDVVKTRFI------NSLPGQYPSVPSCA 254 Query: 266 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 + M EG F+KG ++ ++F+ E+L K Sbjct: 255 MTMYTKEGPAAFFKGFAPSFLRLGSWNVIMFVCFEQLKK 293
>UCP1_MOUSE (P12242) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 14 VKIFSAGVSACL-ADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPK 72 Query: 233 FYKGMGTKIVQSVFAASV 180 Y G+ I + + AS+ Sbjct: 73 LYSGLPAGIQRQISFASL 90 Score = 37.4 bits (85), Expect = 0.042 Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 4/159 (2%) Frame = -3 Query: 614 KPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKR 438 KPR GT A R + +S WKG P L+ V + + Y+ + L + + Sbjct: 150 KPRYTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVNNK---- 205 Query: 437 FPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 267 I A +V L +A T++ P+ VVK+R + +Y Sbjct: 206 -----ILADDVPCHLLSALVAGFCTTLLASPVDVVKTRFI------NSLPGQYPSVPSCA 254 Query: 266 LKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 + M EG F+KG ++ ++F+ E+L K Sbjct: 255 MSMYTKEGPTAFFKGFVASFLRLGSWNVIMFVCFEQLKK 293
>UCP1_MESAU (P04575) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/78 (33%), Positives = 41/78 (52%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 +++F G A L A ++T+PL K RLQ + E ++ RY G L I + + EGL Sbjct: 14 VKIFSAGVAACL-ADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGLPK 72 Query: 233 FYKGMGTKIVQSVFAASV 180 Y G+ I + + AS+ Sbjct: 73 LYSGLPAGIQRQISFASL 90 Score = 37.7 bits (86), Expect = 0.032 Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 7/174 (4%) Frame = -3 Query: 650 ILKDRL---AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 ++K RL + L KPR GT A R + S WKG P L+ V ++ + Y Sbjct: 135 VVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLLRNVIINCVELVTY 194 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 + + L + + I A +V L +A T + P VVK+R Sbjct: 195 DLMKGALVNNQ---------ILADDVPCHLLSAFVAGFCTTFLASPADVVKTRFI----- 240 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 + +Y + M+ EG F+KG ++ ++F+ E+L K Sbjct: 241 -NSLPGQYPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKK 293
>UCP2_BRARE (Q9W720) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 42.0 bits (97), Expect = 0.002 Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 1/155 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKKN 423 G I + R G + GL+ L + S++ +Y+++ K+ +K S Sbjct: 62 GVFGTISTMVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSV-KQFYTKGSDHAGIGSR 120 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + A G A V P V+K R QA+ G A+ RY T+DA + + EG Sbjct: 121 LMA------GCTTGAMAVAVAQPTDVLKVRFQAQVSAG--ASKRYHSTMDAYRTIAKEEG 172 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEELVKFVIL 138 G +KG G I ++ + +V +L+K +L Sbjct: 173 FRGLWKGTGPNITRNAI-VNCTELVTYDLIKDALL 206 Score = 36.2 bits (82), Expect = 0.094 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS--------RYTGTLDAIL 264 TA F+ A A + T+PL K RLQ + G N AS +Y G I Sbjct: 12 TATVKFIGAGTAACIADLFTFPLDTAKVRLQIQ---GENKASTNMGRGPVKYRGVFGTIS 68 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 M+R EG Y G+ + + + ASV + + + +F Sbjct: 69 TMVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQF 107
>ADT1_ANOGA (Q27238) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 301 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/147 (21%), Positives = 61/147 (41%), Gaps = 1/147 (0%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKN 423 G + +++ + GI G ++G N S+Q +IY G KN Sbjct: 158 GLLDCLKKTVKSDGIIGLYRGF--------NVSVQGIIIYRAAYFGCFDTAKGMLPDPKN 209 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + + + + + +++YP V+ R+ + ++ Y TLD +K+ + EG Sbjct: 210 TSIFVSWAIAQVVTTASGIISYPFDTVRRRMMMQSGRAKSEVM-YKNTLDCWVKIGKQEG 268 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKE 162 F+KG + +++ A VL E Sbjct: 269 SGAFFKGAFSNVLRGTGGALVLVFYDE 295
>ADT_DROME (Q26365) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) (Stress sensitive B protein) Length = 312 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/136 (22%), Positives = 56/136 (41%), Gaps = 5/136 (3%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 G + + +E G S FW+G + +I ++ K++ K Sbjct: 68 GMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKN------ 121 Query: 419 TAMEVFLLGAIAKLGATVVT-----YPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI 255 T + G +A GA T YPL ++RL A + G+ +TG + + K+ Sbjct: 122 TQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAA--DTGKGGQREFTGLGNCLTKIF 179 Query: 254 RYEGLHGFYKGMGTKI 207 + +G+ G Y+G G + Sbjct: 180 KSDGIVGLYRGFGVSV 195
>MPCP_RAT (P16036) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 356 Score = 41.6 bits (96), Expect = 0.002 Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 7/164 (4%) Frame = -3 Query: 611 PRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKR 438 P+ Y G +E G+ G KG PTLI + +F YE K L S G+ Sbjct: 91 PQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVF-KALYSNILGEE 149 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILK 261 T++ + A A+ A + P+ K R+Q + Y TL +A+ K Sbjct: 150 NTYLWRTSLYL-AASASAEFFADIALAPMEAAKVRIQTQPG--------YANTLREAVPK 200 Query: 260 MIRYEGLHGFYKGMG----TKIVQSVFAASVLFMVKEELVKFVI 141 M + EGL+ FYKG+ +I ++ + E L KFV+ Sbjct: 201 MYKEEGLNAFYKGVAPVWMRQIPYTMMKFACFERTVEALYKFVV 244 Score = 34.7 bits (78), Expect = 0.27 Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 5/134 (3%) Frame = -3 Query: 590 QAIREVYRESGISGFWKGLIPT-LIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITA 414 +A+ ++Y+E G++ F+KG+ P + + ++F +E + L K P+ T Sbjct: 196 EAVPKMYKEEGLNAFYKGVAPVWMRQIPYTMMKFACFERTVEALYKFVVPK--PRSECTK 253 Query: 413 ME----VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 E F+ G IA + +V++P V S L +E G A+ ++++ Sbjct: 254 AEQLVVTFVAGYIAGVFCAIVSHPADSVVSVL--NKEKGSTAS-----------QVLQRL 300 Query: 245 GLHGFYKGMGTKIV 204 G G +KG+ +I+ Sbjct: 301 GFRGVWKGLFARII 314
>ADT3_PIG (Q6QRN9) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) Length = 297 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 2/141 (1%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSIQ-FMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 ++ + GI G ++G N S+Q +IY + G +N + + Sbjct: 162 KITKSDGIRGLYQGF--------NVSVQGIIIYRAAYFGVYGTAKGMLPDPRNTHIVVSW 213 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAAS-RYTGTLDAILKMIRYEGLHGFYK 225 ++ A V +YP V+ R+ + GR A Y GTLD K+ + EG F+K Sbjct: 214 MIAQTVTAVAGVFSYPFDTVRRRMMMQS--GRKGADIMYKGTLDCWRKIFKDEGGKAFFK 271 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G + +++ + A VL + E Sbjct: 272 GAWSNVLRGMGGAFVLVLYDE 292
>MFN2B_XENLA (Q68F18) Mitoferrin-2B (Mitochondrial iron transporter 2-B) (Solute| carrier family 25 member 28-B) Length = 186 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/92 (31%), Positives = 49/92 (53%) Frame = -3 Query: 425 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 N+TA L GA+A + + YP+ VK+R+Q+ Q + A+RY +DA+ K++R E Sbjct: 76 NVTAH--MLAGAVAGVMEHCLMYPVDCVKTRMQSLQP---DPAARYRNVMDALSKIVRTE 130 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 G +G+ + A ++ F E+L K Sbjct: 131 GFWRPLRGLNVTATGAGPAHALYFACYEKLKK 162
>MFN2A_XENLA (Q6GLJ0) Mitoferrin-2A (Mitochondrial iron transporter 2-A) (Solute| carrier family 25 member 28-A) Length = 186 Score = 41.6 bits (96), Expect = 0.002 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 7/139 (5%) Frame = -3 Query: 545 WKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPK-------KNITAMEVFLLGAI 387 W P+++ S + +E+ S R+ S P+ N+T L GA+ Sbjct: 29 WSAAGPSVLESEGGSGGPLAFESTSSRILELASKDNEPEYEALPDGSNVTTH--MLAGAV 86 Query: 386 AKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKI 207 A + + YP+ VK+R+Q+ Q + A+RY +DA+ K++R EG +G+ Sbjct: 87 AGVMEHCLMYPVDCVKTRMQSLQP---DPAARYRNVMDALSKIVRTEGFWRPLRGLNVTA 143 Query: 206 VQSVFAASVLFMVKEELVK 150 + A ++ F E+L K Sbjct: 144 TGAGPAHALYFACYEKLKK 162
>MTCH2_MOUSE (Q791V5) Mitochondrial carrier homolog 2| Length = 303 Score = 41.2 bits (95), Expect = 0.003 Identities = 23/67 (34%), Positives = 40/67 (59%) Frame = -3 Query: 389 IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTK 210 IA+ AT++T+P V+ R Q IGR S+Y G D+I+ + R EG+ GF+ G+ + Sbjct: 129 IARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIVTIYREEGIVGFFAGLIPR 185 Query: 209 IVQSVFA 189 ++ + + Sbjct: 186 LLGDIIS 192 Score = 35.0 bits (79), Expect = 0.21 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 438 G +I +YRE GI GF+ GLIP L + +CN + L + + K Sbjct: 161 GLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINTYALDSGVSTMNEMKS 220 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 309 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>MPCP_MOUSE (Q8VEM8) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 357 Score = 41.2 bits (95), Expect = 0.003 Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 7/164 (4%) Frame = -3 Query: 611 PRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKR 438 P+ Y G +E G+ G KG PTLI + +F YE K L S G+ Sbjct: 92 PQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVF-KALYSNILGEE 150 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILK 261 T++ + A A+ A + P+ K R+Q + Y TL +A+ K Sbjct: 151 NTYLWRTSLYL-ASSASAEFFADIALAPMEAAKVRIQTQPG--------YANTLREAVPK 201 Query: 260 MIRYEGLHGFYKGMG----TKIVQSVFAASVLFMVKEELVKFVI 141 M + EGL+ FYKG+ +I ++ + E L KFV+ Sbjct: 202 MYKEEGLNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVV 245 Score = 34.3 bits (77), Expect = 0.36 Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 5/134 (3%) Frame = -3 Query: 590 QAIREVYRESGISGFWKGLIPT-LIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITA 414 +A+ ++Y+E G++ F+KG+ P + + ++F +E + L K P+ T Sbjct: 197 EAVPKMYKEEGLNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPK--PRSECTK 254 Query: 413 ME----VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 E F+ G IA + +V++P V S L +E G A+ ++++ Sbjct: 255 AEQLVVTFVAGYIAGVFCAIVSHPADSVVSVL--NKEKGSTAS-----------QVLQRL 301 Query: 245 GLHGFYKGMGTKIV 204 G G +KG+ +I+ Sbjct: 302 GFRGVWKGLFARII 315
>YM39_YEAST (Q03829) Putative mitochondrial carrier YMR166C| Length = 368 Score = 40.8 bits (94), Expect = 0.004 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 17/157 (10%) Frame = -3 Query: 587 AIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAM 411 AI+ V +E G + G TL + ++QF YE ++L K K ++ Sbjct: 199 AIKTVIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKF-RQLAFKIEQKDGRDGELSIP 257 Query: 410 EVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEI----------------GRNAASRYTGT 279 L GA A A ++T P+ VVK+R+Q +Q GR AA + + Sbjct: 258 NEILTGACAGGLAGIITTPMDVVKTRVQTQQPPSQSNKSYSVTHPHVTNGRPAALSNSIS 317 Query: 278 LDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMV 168 L ++ + + EG+ GF+ G+G + V + +S++ ++ Sbjct: 318 L-SLRTVYQSEGVLGFFSGVGPRFVWTSVQSSIMLLL 353
>MFRN2_HUMAN (Q96A46) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) Length = 364 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/82 (32%), Positives = 45/82 (54%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA+A + V YP+ VK+R+Q+ Q + A+RY L+A+ ++IR EGL +G+ Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQP---DPAARYRNVLEALWRIIRTEGLWRPMRGLN 135 Query: 215 TKIVQSVFAASVLFMVKEELVK 150 + A ++ F E+L K Sbjct: 136 VTATGAGPAHALYFACYEKLKK 157
>GDC_RAT (P16261) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) (Fragment) Length = 322 Score = 40.4 bits (93), Expect = 0.005 Identities = 36/152 (23%), Positives = 68/152 (44%), Gaps = 10/152 (6%) Frame = -3 Query: 599 GTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQS------KRSG 444 G I A + +Y +E G GF++GL+PT++ M S+ F + TL S R Sbjct: 173 GIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYASVSFFTFGTLKSVGLSYAPTLLGRPS 232 Query: 443 KRFPKKNITAMEVFLL-GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 267 P + + LL G +A+ A ++YP V + R+Q + + + + Sbjct: 233 SDNPNVLVLKTHINLLCGGVARAIAQTISYPFDVTRRRMQLGAVLPE--FEKCLTMRETM 290 Query: 266 LKMIRYEGL-HGFYKGMGTKIVQSVFAASVLF 174 + + G+ G Y+G+ ++ + + +V F Sbjct: 291 KYVYGHHGIRRGLYRGLSLNYIRCIPSQAVAF 322
>GDC_BOVIN (Q01888) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) Length = 330 Score = 40.0 bits (92), Expect = 0.007 Identities = 38/161 (23%), Positives = 70/161 (43%), Gaps = 10/161 (6%) Frame = -3 Query: 599 GTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQS------KRSG 444 G I A + +Y +E G GF++GL+PT++ M + F + TL S R Sbjct: 168 GIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPTLLGRPS 227 Query: 443 KRFPKKNITAMEVFLL-GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 267 P + + LL G +A A ++YP V + R+Q + + + + Sbjct: 228 SDNPNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLPE--FEKCLTMRETM 285 Query: 266 LKMIRYEGLH-GFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 + + G+ G Y+G+ ++ V + +V F E + +F Sbjct: 286 KYVYGHHGIRKGLYRGLSLNYIRCVPSQAVAFTTYELMKQF 326
>ODC_HUMAN (Q9BQT8) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 40.0 bits (92), Expect = 0.007 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 7/132 (5%) Frame = -3 Query: 593 IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 417 + + R +++ G+ GF+KG++P ++ +++F +E K L Sbjct: 57 VDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLL------------GYV 104 Query: 416 AMEVFLLGAIAKLGA----TVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 ++ L AIA LG+ +V P VVK LQA RN + T+ ++I+ Sbjct: 105 SLSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQA----NRNTFAEQPSTVGYARQIIKK 160 Query: 248 E--GLHGFYKGM 219 E GL G KG+ Sbjct: 161 EGWGLQGLNKGL 172 Score = 36.6 bits (83), Expect = 0.072 Identities = 26/91 (28%), Positives = 42/91 (46%) Frame = -3 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 237 A + G A L + +PL VVK+R Q ++ + Y +D+ + + EGL Sbjct: 13 ASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQR--CATDPNSYKSLVDSFRMIFQMEGLF 70 Query: 236 GFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 GFYKG+ I+ +V F E+ K + Sbjct: 71 GFYKGILPPILAETPKRAVKFFTFEQYKKLL 101 Score = 34.3 bits (77), Expect = 0.36 Identities = 22/81 (27%), Positives = 40/81 (49%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 F +G ++ A+V+ P V KSR+Q Q + +Y + + + EG+ YK Sbjct: 211 FGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEI--KYRTCFKTMATVYQEEGILALYK 268 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G+ KI++ +V+ +V E Sbjct: 269 GLLPKIMRLGPGGAVMLLVYE 289
>YE08_SCHPO (O13805) Putative mitochondrial carrier C17H9.08| Length = 326 Score = 40.0 bits (92), Expect = 0.007 Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 1/120 (0%) Frame = -3 Query: 602 YGTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKRFPKK 426 +G +AI+ +Y G+ G ++G TL V I+F+ YE Q +R R P+ Sbjct: 60 HGLYKAIKHIYHVYGLHGLYQGHTATLYRVFPYAGIKFVAYE------QVRRVLIRDPEH 113 Query: 425 NITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 A FL G++A + TYPL +++ RL G+N TL + K I +E Sbjct: 114 ETHARR-FLSGSLAGTCSVFFTYPLELIRVRLAYITNTGKNP------TLTQVTKDIFHE 166 Score = 30.0 bits (66), Expect = 6.7 Identities = 24/87 (27%), Positives = 35/87 (40%) Frame = -3 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 222 + G A A V PL VK Q R A G AI + GLHG Y+G Sbjct: 22 IAGGTAGCVAKSVVAPLDRVKILYQTNHASYRGYAYSRHGLYKAIKHIYHVYGLHGLYQG 81 Query: 221 MGTKIVQSVFAASVLFMVKEELVKFVI 141 + + A + F+ E++ + +I Sbjct: 82 HTATLYRVFPYAGIKFVAYEQVRRVLI 108
>MFRN1_BRARE (Q287T7) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Protein frascati) Length = 332 Score = 39.7 bits (91), Expect = 0.009 Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 4/166 (2%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQ-AIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYET 477 +K R+ L + Y ++ A++ + R G+ +GL T ++ P+ + F YE Sbjct: 57 VKTRMQSLQPDPKAQYRSVYGALKRIVRTEGLLRPLRGLNIT-VLGAGPAHALYFACYER 115 Query: 476 LSKRLQSK-RSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNA 300 + + L ++G N A G++A + V P VVK R+Q Sbjct: 116 IKRSLSDVIQNGGNSHIANGVA------GSVATVLHDAVMNPAEVVKQRMQMYN------ 163 Query: 299 ASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 S Y D +L + R EGL FY+ T++ ++ +V F+ E Sbjct: 164 -SPYRSLYDCVLMVSRKEGLAAFYRSYSTQLTMNIPFQAVHFITYE 208 Score = 32.3 bits (72), Expect = 1.4 Identities = 21/80 (26%), Positives = 42/80 (52%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA+A + V YP+ VK+R+Q+ Q + ++Y A+ +++R EGL +G+ Sbjct: 40 GAVAGILEHTVMYPVDSVKTRMQSLQP---DPKAQYRSVYGALKRIVRTEGLLRPLRGLN 96 Query: 215 TKIVQSVFAASVLFMVKEEL 156 ++ + A ++ F E + Sbjct: 97 ITVLGAGPAHALYFACYERI 116
>ODC_MOUSE (Q8BZ09) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 39.7 bits (91), Expect = 0.009 Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 6/137 (4%) Frame = -3 Query: 611 PRPYGTIQ-AIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRL--QSKRSG 444 P+ Y T++ + + ++R G+ GF+KG+IP ++ +++F +E K L S G Sbjct: 49 PQSYRTVRGSFQMIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPG 108 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 F + G + L VV P VVK LQ + RN T Sbjct: 109 LTF----------LIAGLGSGLTEAVVVNPFEVVKVGLQ----VNRNLFKEQPSTFAYAR 154 Query: 263 KMIRYEGL--HGFYKGM 219 ++I+ EGL G KG+ Sbjct: 155 QIIKKEGLGFQGLNKGL 171 Score = 35.8 bits (81), Expect = 0.12 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI-RYEGLHGFYKGM 219 G A L + +PL VVK+R Q ++ + + R T+ +MI R EGL GFYKG+ Sbjct: 19 GGSAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYR---TVRGSFQMIFRTEGLFGFYKGI 75 Query: 218 GTKIVQSVFAASVLFMVKEELVKFV 144 I+ +V F E KF+ Sbjct: 76 IPPILAETPKRAVKFSTFELYKKFL 100 Score = 35.0 bits (79), Expect = 0.21 Identities = 34/149 (22%), Positives = 62/149 (41%), Gaps = 4/149 (2%) Frame = -3 Query: 596 TIQAIREVYRESGIS--GFWKGLIPTLIM--VCNPSIQFMIYETLSKRLQSKRSGKRFPK 429 T R++ ++ G+ G KGL TL + N + F Y + + S + Sbjct: 149 TFAYARQIIKKEGLGFQGLNKGLTATLGRHGIFN-MVYFGFYHNVKNIIPSSKD------ 201 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 + + F +G ++ +V P V KSR+Q Q + +Y + + R Sbjct: 202 PTLEFLRKFGIGFVSGTMGSVFNIPFDVAKSRIQGPQPVPGEI--KYRSCFKTMEMIYRE 259 Query: 248 EGLHGFYKGMGTKIVQSVFAASVLFMVKE 162 EG+ YKG+ K+++ V+ +V E Sbjct: 260 EGILALYKGLVPKVMRLGPGGGVMLLVYE 288
>MTCH2_BOVIN (Q9N285) Mitochondrial carrier homolog 2| Length = 303 Score = 39.7 bits (91), Expect = 0.009 Identities = 33/133 (24%), Positives = 66/133 (49%), Gaps = 9/133 (6%) Frame = -3 Query: 560 GISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQ----SKRSGKRFPKKNITA-----ME 408 G G + GL P L C+ + +++ + + Q ++ SG +K +++ ++ Sbjct: 66 GKRGLFTGLTPRL---CSGILGTVVHGKVLQHYQECDKAEESGSGNVQKEVSSSFDRVIK 122 Query: 407 VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFY 228 +A+ AT++T+P V+ R Q IGR S+Y G D+I + R EG+ GF+ Sbjct: 123 ETTREMMARSAATLITHPFHVITLRSMV-QFIGRE--SKYCGLCDSIATIYREEGILGFF 179 Query: 227 KGMGTKIVQSVFA 189 G+ +++ + + Sbjct: 180 AGLIPRLLGDIIS 192 Score = 35.8 bits (81), Expect = 0.12 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFMIYETLSKRLQSKRSGKR 438 G +I +YRE GI GF+ GLIP L + +CN + L + + K Sbjct: 161 GLCDSIATIYREEGILGFFAGLIPRLLGDIISLWLCNSLAYLVNTYALDSGVSTMNEMKS 220 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG 309 + + A+ A+++TYP ++V S L A G Sbjct: 221 YSQ------------AVTGFFASMLTYPFVLV-SNLMAVNNCG 250
>MFRN2_MOUSE (Q8R0Z5) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) Length = 364 Score = 39.7 bits (91), Expect = 0.009 Identities = 26/82 (31%), Positives = 45/82 (54%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA+A + V YP+ VK+R+Q+ Q + A+RY L+A+ +++R EGL +G+ Sbjct: 79 GAVAGILEHCVMYPIDCVKTRMQSLQP---DPAARYRNVLEALWRIMRTEGLWRPMRGLN 135 Query: 215 TKIVQSVFAASVLFMVKEELVK 150 + A ++ F E+L K Sbjct: 136 VTATGAGPAHALYFACYEKLKK 157
>UCP4_HUMAN (O95847) Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier| family 25 member 27) Length = 323 Score = 39.3 bits (90), Expect = 0.011 Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = -3 Query: 629 KLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSK 453 KL+ + R G A ++ E GI G W G +P + ++ Y+T+ L Sbjct: 162 KLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLN 221 Query: 452 RSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 273 + NI M L + L A+++ P V+KSR+ + + Y + D Sbjct: 222 TP----LEDNI--MTHGLSSLCSGLVASILGTPADVIKSRIMNQPRDKQGRGLLYKSSTD 275 Query: 272 AILKMIRYEGLHGFYKG 222 +++ ++ EG YKG Sbjct: 276 CLIQAVQGEGFMSLYKG 292 Score = 33.5 bits (75), Expect = 0.61 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 7/94 (7%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI-------GRNAASRYTGTLDAILKMIRYE 246 FLL A A + T+PL + K+RLQ + E G ++ Y G + L +I E Sbjct: 23 FLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEE 82 Query: 245 GLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 G ++G+ I + V + + E L + V Sbjct: 83 GFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVV 116
>GDC_MOUSE (Q8C0K5) Grave disease carrier protein homolog (GDC) (Mitochondrial| solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 39.3 bits (90), Expect = 0.011 Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 13/164 (7%) Frame = -3 Query: 599 GTIQAIREVY-RESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQS------KRSG 444 G I A + +Y +E G GF++GL+PT++ M + F + TL S R Sbjct: 170 GIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALLGRPS 229 Query: 443 KRFPKKNITAMEVFLL-GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAI 267 P + + LL G +A A ++YP V + R+Q + + L Sbjct: 230 SDNPNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVL-----PEFEKCLTMR 284 Query: 266 LKMIRYEGLH----GFYKGMGTKIVQSVFAASVLFMVKEELVKF 147 M G H G Y+G+ ++ + + +V F E + +F Sbjct: 285 ETMKYVYGQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQF 328
>MFRN2_BRARE (Q7T292) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) Length = 376 Score = 38.9 bits (89), Expect = 0.015 Identities = 25/84 (29%), Positives = 45/84 (53%) Frame = -3 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 222 L GA+A + + +P+ VK+R+Q+ Q A+RY +DA+ +++R EG+ +G Sbjct: 82 LAGAVAGIMEHCLMFPIDCVKTRMQSLQP---EPAARYRNVMDALWRIMRTEGIWRPIRG 138 Query: 221 MGTKIVQSVFAASVLFMVKEELVK 150 + V + A ++ F E L K Sbjct: 139 LNITAVGAGPAHALYFACYERLKK 162
>ODC_RAT (Q99JD3) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 38.9 bits (89), Expect = 0.015 Identities = 27/84 (32%), Positives = 39/84 (46%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 G A L + +PL VVK+R Q ++ + Y D+ + R EGL GFYKG+ Sbjct: 19 GGCAGLVEICLMHPLDVVKTRFQVQRSV--TDPQSYKSLRDSFQVIFRTEGLFGFYKGII 76 Query: 215 TKIVQSVFAASVLFMVKEELVKFV 144 I+ +V F E KF+ Sbjct: 77 PPILAETPKRAVKFSTFELYKKFL 100 Score = 38.5 bits (88), Expect = 0.019 Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 6/136 (4%) Frame = -3 Query: 611 PRPYGTIQ-AIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRL--QSKRSG 444 P+ Y +++ + + ++R G+ GF+KG+IP ++ +++F +E K L S G Sbjct: 49 PQSYKSLRDSFQVIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPG 108 Query: 443 KRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 FP + G + L VV P VVK LQ + RN + T Sbjct: 109 LTFP----------IAGLGSGLTEAVVVNPFEVVKVGLQ----VNRNMFTEQPSTFAYAR 154 Query: 263 KMIRYE--GLHGFYKG 222 ++I+ E G G KG Sbjct: 155 QIIKKEGWGFQGLNKG 170 Score = 34.7 bits (78), Expect = 0.27 Identities = 22/81 (27%), Positives = 38/81 (46%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 F +G ++ +V P V KSR+Q Q + +Y G + + R EG+ YK Sbjct: 210 FGIGFVSGTVGSVFNIPFDVAKSRIQGPQPVPGEI--KYRGCFKTMETVYREEGILALYK 267 Query: 224 GMGTKIVQSVFAASVLFMVKE 162 G+ K+++ V+ +V E Sbjct: 268 GLLPKVMRLGPGGGVMLLVYE 288 Score = 30.0 bits (66), Expect = 6.7 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNP--SIQFMIYE 480 G + + VYRE GI +KGL+P +M P + ++YE Sbjct: 248 GCFKTMETVYREEGILALYKGLLPK-VMRLGPGGGVMLLVYE 288
>MPCP_HUMAN (Q00325) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 38.9 bits (89), Expect = 0.015 Identities = 45/164 (27%), Positives = 67/164 (40%), Gaps = 7/164 (4%) Frame = -3 Query: 611 PRPY-GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKR 438 P+ Y G +E G+ G KG PT + + +F YE K L S G+ Sbjct: 97 PQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVF-KVLYSNMLGEE 155 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILK 261 T++ + A A+ A + P+ K R+Q + Y TL DA K Sbjct: 156 NTYLWRTSLYL-AASASAEFFADIALAPMEAAKVRIQTQPG--------YANTLRDAAPK 206 Query: 260 MIRYEGLHGFYKGMG----TKIVQSVFAASVLFMVKEELVKFVI 141 M + EGL FYKG+ +I ++ + E L KFV+ Sbjct: 207 MYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVV 250
>UCP1_DICGR (Q8K404) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 38.5 bits (88), Expect = 0.019 Identities = 25/78 (32%), Positives = 39/78 (50%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 ++ F G A L A ++T+PL K RLQ + E ++ RY G L I + + EG Sbjct: 15 VKTFSAGISACL-ADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGWPK 73 Query: 233 FYKGMGTKIVQSVFAASV 180 Y G+ I + + AS+ Sbjct: 74 LYSGLPAGIQRQISFASL 91 Score = 36.2 bits (82), Expect = 0.094 Identities = 42/174 (24%), Positives = 68/174 (39%), Gaps = 7/174 (4%) Frame = -3 Query: 650 ILKDRL---AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 ++K RL + L KPR GT A R + S WKG P L+ V + + Y Sbjct: 136 VVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLMRNVIINRTELVTY 195 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 + + L + + I A +V L +A T + P VVK+R Sbjct: 196 DLMKGALVNNQ---------ILADDVPCHLLSALVAGFCTTFLASPADVVKTRFI----- 241 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVK 150 + +Y + M+ EG F+KG ++ ++F+ E+L K Sbjct: 242 -NSLPGQYPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASWNVIMFVCFEQLKK 294
>MRS3_YEAST (P10566) Mitochondrial RNA-splicing protein MRS3| Length = 314 Score = 38.5 bits (88), Expect = 0.019 Identities = 40/171 (23%), Positives = 70/171 (40%), Gaps = 3/171 (1%) Frame = -3 Query: 647 LKDRLAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCNPS--IQFMIYETL 474 LK R+ +++ + I + G WKG + ++I+ P+ + F YE Sbjct: 57 LKTRIQSANAKSLSAKNMLSQISHISTSEGTLALWKG-VQSVILGAGPAHAVYFGTYEFC 115 Query: 473 SKRL-QSKRSGKRFPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAA 297 K L S + P K + GA A + + P +K R+Q +A Sbjct: 116 KKNLIDSSDTQTHHPFKTAIS------GACATTASDALMNPFDTIKQRIQLN-----TSA 164 Query: 296 SRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 S + T ++ + EGL FY T +V ++ A+ F++ E KF+ Sbjct: 165 SVWQTTK----QIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYESSTKFL 211
>YDE9_SCHPO (Q10442) Putative mitochondrial carrier C12B10.09| Length = 345 Score = 38.1 bits (87), Expect = 0.025 Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Frame = -3 Query: 434 PKKNITAMEVF-LLGA--IAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAIL 264 P K +AM F LGA A L + +P+ +K+RLQAK +N Sbjct: 73 PSKRHSAMSFFEALGAGICAGLAVDLSLFPIDTLKTRLQAKGGFVKNG------------ 120 Query: 263 KMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 G HG Y+G+G+ +V S AS+ F E + Sbjct: 121 ------GFHGVYRGLGSILVGSAPGASLFFTTYENM 150
>GHC2_HUMAN (Q9H1K4) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 37.7 bits (86), Expect = 0.032 Identities = 18/63 (28%), Positives = 31/63 (49%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 G +A L +P+ + K+RLQ ++ + Y G +D ++K R EG G Y+G Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQ-----NQHGKAMYKGMIDCLMKTARAEGFFGMYRGAA 69 Query: 215 TKI 207 + Sbjct: 70 VNL 72 Score = 31.6 bits (70), Expect = 2.3 Identities = 36/162 (22%), Positives = 67/162 (41%), Gaps = 20/162 (12%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI 420 G I + + R G G ++G L +V + +RL + +R K + Sbjct: 47 GMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEM 106 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIG---RNAAS--------------- 294 A G A + VVT P+ ++K +LQ + + +AS Sbjct: 107 LA------GCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSAST 160 Query: 293 --RYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 R + TL A +++R +GL G Y+G+G +++ + + + F Sbjct: 161 HRRPSATLIA-WELLRTQGLAGLYRGLGATLLRDIPFSIIYF 201
>UCP1_RABIT (P14271) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 37.7 bits (86), Expect = 0.032 Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 7/172 (4%) Frame = -3 Query: 650 ILKDRL---AKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIY 483 ++K RL + L KPR GT A R + ++ WKG P L+ V + + Y Sbjct: 135 VVKVRLQAQSHLHGLKPRYTGTYNAYRIIATTESLTSLWKGTTPNLLRNVIINCTELVTY 194 Query: 482 ETLSKRLQSKRSGKRFPKKNITAMEV---FLLGAIAKLGATVVTYPLLVVKSRLQAKQEI 312 + + L + I A +V F+ IA T+++ P+ VVK+R Sbjct: 195 DLMKGAL---------VRNEILADDVPCHFVSALIAGFCTTLLSSPVDVVKTRFI----- 240 Query: 311 GRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 + +Y + + M EG F+KG ++ ++F+ E+L Sbjct: 241 -NSPPGQYASVPNCAMTMFTKEGPTAFFKGFVPSFLRLGSWNVIMFVCFEKL 291 Score = 37.7 bits (86), Expect = 0.032 Identities = 25/89 (28%), Positives = 43/89 (48%) Frame = -3 Query: 413 MEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHG 234 +++F G A L A V+T+PL K R Q + E + RY G L I + + EG Sbjct: 15 VKIFSAGVAACL-ADVITFPLDTAKVRQQIQGEFPITSGIRYKGVLGTITTLAKTEGPLK 73 Query: 233 FYKGMGTKIVQSVFAASVLFMVKEELVKF 147 Y G+ + + + AS+ + + + +F Sbjct: 74 LYSGLPAGLQRQISFASLRIGLYDTVQEF 102
>MPCP_BOVIN (P12234) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 37.4 bits (85), Expect = 0.042 Identities = 46/164 (28%), Positives = 67/164 (40%), Gaps = 7/164 (4%) Frame = -3 Query: 611 PRPYGTI-QAIREVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKR 438 P+ Y +I +E G G KG PT I + +F YE K L S G+ Sbjct: 97 PQKYKSIFNGFSVTLKEDGFRGLAKGWAPTFIGYSLQGLCKFGFYEVF-KVLYSNMLGEE 155 Query: 437 FPKKNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTL-DAILK 261 T++ + A A+ A + P+ K R+Q + Y TL DA K Sbjct: 156 NAYLWRTSLYL-AASASAEFFADIALAPMEAAKVRIQTQPG--------YANTLRDAAPK 206 Query: 260 MIRYEGLHGFYKGMG----TKIVQSVFAASVLFMVKEELVKFVI 141 M + EGL FYKG+ +I ++ + E L KFV+ Sbjct: 207 MYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVV 250
>DIC_MOUSE (Q9QZD8) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 37.4 bits (85), Expect = 0.042 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 1/120 (0%) Frame = -3 Query: 578 EVYRESGISGFWKGLIPTLIMVCNPSI-QFMIYETLSKRLQSKRSGKRFPKKNITAMEVF 402 +V R G + GL +L S+ +F IYET+ + G + Sbjct: 49 QVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGP------LPFYNKV 102 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 222 LLG I+ L V P +V R+Q ++ + Y+ LD + ++ R E L + G Sbjct: 103 LLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSG 162 Score = 36.2 bits (82), Expect = 0.094 Identities = 22/80 (27%), Positives = 39/80 (48%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 G +A GA T+PL ++K LQ +QE+ R TG L+++R +G Y G+ Sbjct: 12 GGLASCGAACCTHPLDLLKVHLQTQQEV----KLRMTG---MALQVVRTDGFLALYNGLS 64 Query: 215 TKIVQSVFAASVLFMVKEEL 156 + + + + F + E + Sbjct: 65 ASLCRQMTYSLTRFAIYETM 84
>DIC1_YEAST (Q06143) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) (DTP) Length = 298 Score = 37.0 bits (84), Expect = 0.055 Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 8/147 (5%) Frame = -3 Query: 611 PRPYGTI-QAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKRSGKR 438 P P T+ + + + G+ G + GL ++ C +++F Y+ L + + Sbjct: 45 PMPKPTLFRMLESILANEGVVGLYSGLSAAVLRQCTYTTVRFGAYDLLKENV-------- 96 Query: 437 FPKKNITAMEVFL-----LGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLD 273 P++ +T M L GAI L VV R+Q + Y +D Sbjct: 97 IPREQLTNMAYLLPCSMFSGAIGGLAGNFAD----VVNIRMQNDSALEAAKRRNYKNAID 152 Query: 272 AILKMIRYE-GLHGFYKGMGTKIVQSV 195 + K+ RYE GL + G +V+ + Sbjct: 153 GVYKIYRYEGGLKTLFTGWKPNMVRGI 179 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILK-MIRYEGLHGFYKGM 219 G A + AT+VT+PL + K RLQ AA TL +L+ ++ EG+ G Y G+ Sbjct: 20 GGAAGIFATMVTHPLDLAKVRLQ--------AAPMPKPTLFRMLESILANEGVVGLYSGL 71 Query: 218 GTKIVQSVFAASVLF----MVKEELV 153 +++ +V F ++KE ++ Sbjct: 72 SAAVLRQCTYTTVRFGAYDLLKENVI 97
>ODC_PONPY (Q5RFB7) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 36.6 bits (83), Expect = 0.072 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%) Frame = -3 Query: 593 IQAIREVYRESGISGFWKGLIPTLIM-VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNIT 417 + + R +++ + GF+KG++P ++ +++F +E K L Sbjct: 57 VDSFRMIFQTERLFGFYKGILPPILAETPKRAVKFFTFEQYKKLL------------GYV 104 Query: 416 AMEVFLLGAIAKLGA----TVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 ++ L IA LG+ +V P VVK LQA RN ++ T+ ++I+ Sbjct: 105 SLSPALTFTIAGLGSGLTEAIVVNPFEVVKVGLQA----NRNTFAKQPSTVGYARQIIKK 160 Query: 248 E--GLHGFYKGM 219 E GL G KG+ Sbjct: 161 EGWGLQGLNKGL 172 Score = 36.2 bits (82), Expect = 0.094 Identities = 34/147 (23%), Positives = 66/147 (44%), Gaps = 2/147 (1%) Frame = -3 Query: 596 TIQAIREVYRESG--ISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKN 423 T+ R++ ++ G + G KGL TL + M+Y +++ + P Sbjct: 150 TVGYARQIIKKEGWGLQGLNKGLTATL---GRHGVFNMVYFGFYYNVKNMIPVNKDP--T 204 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 + + F +G ++ A+V+ P V KSR+Q Q + +Y + + + EG Sbjct: 205 LEFLRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEI--KYRTCFKTMATVYQEEG 262 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKE 162 + YKG+ KI++ +V+ +V E Sbjct: 263 ILALYKGLLPKIMRLGPGGAVMLLVYE 289 Score = 33.1 bits (74), Expect = 0.80 Identities = 25/91 (27%), Positives = 41/91 (45%) Frame = -3 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 237 A + G A L + +PL VVK+R Q ++ + Y +D+ + + E L Sbjct: 13 ASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQR--CATDPNSYKSLVDSFRMIFQTERLF 70 Query: 236 GFYKGMGTKIVQSVFAASVLFMVKEELVKFV 144 GFYKG+ I+ +V F E+ K + Sbjct: 71 GFYKGILPPILAETPKRAVKFFTFEQYKKLL 101
>GHC2_MOUSE (Q9DB41) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) (Fragment) Length = 312 Score = 36.6 bits (83), Expect = 0.072 Identities = 21/63 (33%), Positives = 32/63 (50%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 G IA L +P+ + K+RLQ +Q G++ Y G D ++K R EG G Y+G Sbjct: 12 GGIAGLVGVTCVFPIDLAKTRLQNQQ--GKDV---YRGMTDCLMKTARAEGFLGMYRGAA 66 Query: 215 TKI 207 + Sbjct: 67 VNL 69
>YAD8_SCHPO (Q09834) Putative mitochondrial carrier C4G8.08| Length = 271 Score = 36.2 bits (82), Expect = 0.094 Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -3 Query: 572 YRESGISGFWKGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAMEVFLLG 393 ++ + +++GL +L ++ + + LS +++KR K P A+ + G Sbjct: 38 FKTMPLKAYYRGLPISLTLITPATCLY-----LSTYVEAKRRFK--PSVGEGAILYSICG 90 Query: 392 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG--M 219 A++ ++ V PL V+K+R Q Q+ ++ I + R EGL GFY+G M Sbjct: 91 MTAEVVSSFVWTPLEVIKARTQISQK---------GSVINTISTLARSEGLKGFYRGYWM 141 Query: 218 GTKI 207 G I Sbjct: 142 GVAI 145
>PET8_ASHGO (O60029) Putative mitochondrial carrier protein PET8| Length = 271 Score = 36.2 bits (82), Expect = 0.094 Identities = 24/88 (27%), Positives = 38/88 (43%) Frame = -3 Query: 419 TAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGL 240 T + + GA A VV +P+ +K+RLQAK N G Sbjct: 4 TFLASLVSGAAAGTSTDVVFFPIDTLKTRLQAKGGFFHNG------------------GY 45 Query: 239 HGFYKGMGTKIVQSVFAASVLFMVKEEL 156 G Y+G+G+ +V S AS+ F+ + + Sbjct: 46 RGIYRGLGSAVVASAPGASLFFVTYDSM 73
>GHC2_RAT (Q505J6) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 36.2 bits (82), Expect = 0.094 Identities = 21/63 (33%), Positives = 32/63 (50%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 G IA L +P+ + K+RLQ +Q G++ Y G D ++K R EG G Y+G Sbjct: 15 GGIAGLVGVTCVFPIDLAKTRLQNQQ--GKDV---YKGMTDCLVKTARAEGFLGMYRGAA 69 Query: 215 TKI 207 + Sbjct: 70 VNL 72
>YG5F_YEAST (P53320) Putative mitochondrial carrier YGR257C| Length = 366 Score = 35.4 bits (80), Expect = 0.16 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTLIMVCNPS-IQFMIYETLSKRLQSKRSGKRFPKKN 423 GT++A ++ GI+ W+G+ TL+M + + F YE + +P N Sbjct: 104 GTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIR---DVSPIASTYPTLN 160 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQA 324 GAIA++ A PL +VK++LQ+ Sbjct: 161 -----PLFCGAIARVFAATSIAPLELVKTKLQS 188 Score = 31.2 bits (69), Expect = 3.0 Identities = 12/45 (26%), Positives = 27/45 (60%) Frame = -3 Query: 308 RNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLF 174 +N++ ++ GTL+A K+ EG+ ++G+ ++ ++ A V F Sbjct: 96 KNSSLKFNGTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYF 140
>MTCH1_MOUSE (Q791T5) Mitochondrial carrier homolog 1 (Mitochondrial| carrier-like protein 1) Length = 389 Score = 35.4 bits (80), Expect = 0.16 Identities = 33/126 (26%), Positives = 63/126 (50%), Gaps = 7/126 (5%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-----VCNPSIQFMIYETLSKRLQSKRSGKRFPKKNI--T 417 + + G G ++GL P L+ V S++ + +++ +K K KK + T Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTSLKKVVKET 198 Query: 416 AMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLH 237 + E+ + + + ++ +PL V+ R Q +GR A +Y+G L +I K+ + EGL Sbjct: 199 SYEMMM-----QCVSRMLAHPLHVISMRCMV-QFVGREA--KYSGVLSSIGKIFKEEGLL 250 Query: 236 GFYKGM 219 GF+ G+ Sbjct: 251 GFFVGL 256 Score = 32.0 bits (71), Expect = 1.8 Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 15/101 (14%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFM--------IYETLSKRL 462 G + +I ++++E G+ GF+ GLIP L + CN F+ + +T Sbjct: 235 GVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLG 294 Query: 461 QSKRSGKRFPKK-NITAMEVFLLGAIAKLGATVVTYPLLVV 342 + G +F + I + F++G + +++TYP L+V Sbjct: 295 NDQNPGSQFSQALAIRSYTKFVMG----IAVSMLTYPFLLV 331
>MTCH1_HUMAN (Q9NZJ7) Mitochondrial carrier homolog 1 (Presenilin-associated| protein) Length = 389 Score = 35.4 bits (80), Expect = 0.16 Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 9/128 (7%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIM-----VCNPSIQFMI----YETLSKRLQSKRSGKRFPKKN 423 + + G G ++GL P L+ V S++ + E +S + K S K+ K+ Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKE- 197 Query: 422 ITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEG 243 T+ E+ + + + ++ +PL V+ R Q +GR A +Y+G L +I K+ + EG Sbjct: 198 -TSYEMMM-----QCVSRMLAHPLHVISMRCMV-QFVGREA--KYSGVLSSIGKIFKEEG 248 Query: 242 LHGFYKGM 219 L GF+ G+ Sbjct: 249 LLGFFVGL 256 Score = 32.0 bits (71), Expect = 1.8 Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 15/101 (14%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFWKGLIPTL------IMVCNPSIQFM--------IYETLSKRL 462 G + +I ++++E G+ GF+ GLIP L + CN F+ + +T Sbjct: 235 GVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLG 294 Query: 461 QSKRSGKRFPKK-NITAMEVFLLGAIAKLGATVVTYPLLVV 342 + G +F + I + F++G + +++TYP L+V Sbjct: 295 NDQNPGSQFSQALAIRSYTKFVMG----IAVSMLTYPFLLV 331
>PET8_YEAST (P38921) Putative mitochondrial carrier protein PET8| Length = 284 Score = 34.7 bits (78), Expect = 0.27 Identities = 23/77 (29%), Positives = 34/77 (44%) Frame = -3 Query: 401 LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 222 L GA A +V +P+ +K+RLQAK N G G Y+G Sbjct: 9 LSGAAAGTSTDLVFFPIDTIKTRLQAKGGFFANG------------------GYKGIYRG 50 Query: 221 MGTKIVQSVFAASVLFM 171 +G+ +V S AS+ F+ Sbjct: 51 LGSAVVASAPGASLFFI 67
>MPCP_CAEEL (P40614) Phosphate carrier protein, mitochondrial precursor (PTP)| Length = 340 Score = 33.9 bits (76), Expect = 0.47 Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 5/129 (3%) Frame = -3 Query: 575 VYRESGISGFWKGLIPT-LIMVCNPSIQFMIYETLSKRLQSKRSGKRFPKKNITAME--- 408 +Y+ G++GF+KGL P + + ++F +E + L K P+ + E Sbjct: 185 IYKAEGLTGFYKGLPPLWMRQIPYTMMKFACFEKTVEALYQYVVPK--PRAECSKAEQLV 242 Query: 407 -VFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGF 231 F+ G IA + +V++P V S+L + T ILK + G G Sbjct: 243 VTFVAGYIAGVFCAIVSHPADTVVSKLNQDSQ----------ATAGGILKKL---GFAGV 289 Query: 230 YKGMGTKIV 204 +KG+ +I+ Sbjct: 290 WKGLVPRII 298 Score = 33.5 bits (75), Expect = 0.61 Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Frame = -3 Query: 575 VYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQSKR 450 + ++ G +G WKGL+P +IM+ ++Q+ IY+++ L R Sbjct: 280 ILKKLGFAGVWKGLVPRIIMIGTLTALQWFIYDSVKVALNLPR 322
>GLR27_ARATH (Q8LGN0) Glutamate receptor 2.7 precursor (Ligand-gated ion channel| 2.7) Length = 949 Score = 33.5 bits (75), Expect = 0.61 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 11/118 (9%) Frame = -3 Query: 473 SKRLQSKRSG--KRFPKK-NITAMEVFLLGAIAKLGATVVTYPLLVVKSRL--------Q 327 SK+L++ R K FPKK N M +F L A + A + +KS Sbjct: 292 SKKLKNFRLRWEKMFPKKGNDEEMNIFALRAYDSITALAMAVEKTNIKSLRYDHPIASGN 351 Query: 326 AKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVFAASVLFMVKEELV 153 K +G SRY +L L +R+ GL G ++ + ++ SVF + +E ++ Sbjct: 352 NKTNLGTLGVSRYGPSLLKALSNVRFNGLAGEFELINGQLESSVFDVINIIGSEERII 409
>YHM2_YEAST (Q04013) Mitochondrial DNA replication protein YHM2| Length = 314 Score = 32.3 bits (72), Expect = 1.4 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 5/153 (3%) Frame = -3 Query: 605 PYGTIQAIREVYRESGISGFWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSGKRFPK 429 P + + +Y++ GI G KG+ I + N +F + + ++ K +GK Sbjct: 152 PQSSWSVFKNIYKKEGIRGINKGVNAVAIRQMTNWGSRFGLSRLVEDGIR-KITGKTNKD 210 Query: 428 KNITAMEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRY 249 + E A+ G + P+ V++ +Q+K+E + G + + Sbjct: 211 DKLNPFEKIGASALGG-GLSAWNQPIEVIRVEMQSKKEDPNRPKNLTVG--KTFKYIYQS 267 Query: 248 EGLHGFYKG----MGTKIVQSVFAASVLFMVKE 162 GL G Y+G +G I Q+VF M KE Sbjct: 268 NGLKGLYRGVTPRIGLGIWQTVFMVGFGDMAKE 300
>GLR21_ARATH (O04660) Glutamate receptor 2.1 precursor (Ligand-gated ion channel| 2.1) (AtGLR3) Length = 901 Score = 32.3 bits (72), Expect = 1.4 Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 9/107 (8%) Frame = -3 Query: 485 YETLSKRLQSKRSG--KRFPKKNITAMEVF-------LLGAIAKLGATVVTYPLLVVKSR 333 Y SK L++ RS KRFP ++ ++ L AI + G + +T+ + K Sbjct: 283 YVPRSKELENFRSRWTKRFPISDLNVYGLWAYDATTALALAIEEAGTSNLTFVKMDAKRN 342 Query: 332 LQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMGTKIVQSVF 192 + Q +G S+Y L L +R++GL G ++ + ++ SVF Sbjct: 343 VSELQGLG---VSQYGPKLLQTLSRVRFQGLAGDFQFINGELQPSVF 386
>MFRN1_BOVIN (Q3ZBJ8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 171 Score = 32.0 bits (71), Expect = 1.8 Identities = 22/80 (27%), Positives = 41/80 (51%) Frame = -3 Query: 395 GAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKGMG 216 GA+A + V YP+ VK+R+Q+ + + + YT A+ K+IR EG +G+ Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQS---LNPDPKAHYTSVYGALKKIIRTEGFWRPLRGLN 108 Query: 215 TKIVQSVFAASVLFMVKEEL 156 ++ + A ++ F E + Sbjct: 109 VMMMGAGPAHAMYFACYENM 128
>MPCP_CHOFU (O61703) Phosphate carrier protein, mitochondrial precursor| (Phosphate transport protein) (PTP) Length = 349 Score = 31.6 bits (70), Expect = 2.3 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = -3 Query: 635 LAKLDSEKPRPYGTIQAIREVYRESGISGFWKGLIPTLIMVCN-PSIQFMIYETLSKRLQ 459 ++KL+ +K G+I + G +G WKGL P +IM+ ++Q+ IY+ + L+ Sbjct: 273 VSKLNQDKTATVGSIVG------KLGFAGVWKGLGPRIIMIGTLTALQWFIYDAVKVWLR 326 Query: 458 SKR 450 R Sbjct: 327 MPR 329
>LEU5_YEAST (P38702) Mitochondrial carrier protein LEU5| Length = 357 Score = 31.6 bits (70), Expect = 2.3 Identities = 28/149 (18%), Positives = 60/149 (40%), Gaps = 18/149 (12%) Frame = -3 Query: 548 FWKGLIPTLI-MVCNPSIQFMIYETLSKRLQSKRSG-------------KRFPKKNITAM 411 F++G +PT++ M+ + F ++ L L+S +R KK + Sbjct: 203 FYRGYVPTVLGMIPYAGVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPL 262 Query: 410 EVF---LLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMI-RYEG 243 + + G +A + + YP +++ RLQ + ++ I +I + G Sbjct: 263 RTWAELISGGLAGMASQTAAYPFEIIRRRLQVSALSPKTMYDHKFQSISEIAHIIFKERG 322 Query: 242 LHGFYKGMGTKIVQSVFAASVLFMVKEEL 156 + GF+ G+ ++ + F V E + Sbjct: 323 VRGFFVGLSIGYIKVTPMVACSFFVYERM 351
>MOEA1_MYCTU (O05577) Molybdopterin biosynthesis protein moeA 1| Length = 426 Score = 30.8 bits (68), Expect = 4.0 Identities = 15/65 (23%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Frame = -3 Query: 599 GTIQAIREVYRESGISGFW---KGLIPTLIMVCNPSIQFMIYETLSKRLQSKRSGKRFPK 429 G ++ +R + GF + +PT ++ NP +++E + + L GKR P Sbjct: 282 GEMEVVRVAMHPGSVQGFGQLGRDGVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRHPM 341 Query: 428 KNITA 414 + I + Sbjct: 342 RRIVS 346
>YHM1_YEAST (P38988) Putative mitochondrial carrier protein YHM1/SHM1| Length = 300 Score = 30.4 bits (67), Expect = 5.2 Identities = 18/67 (26%), Positives = 36/67 (53%) Frame = -3 Query: 404 FLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYK 225 F+ + + +V+ PL V+K+R+Q RN + +G L + ++ EG+ F+K Sbjct: 214 FISSIVGACSSLIVSAPLDVIKTRIQ-----NRNFDNPESG-LRIVKNTLKNEGVTAFFK 267 Query: 224 GMGTKIV 204 G+ K++ Sbjct: 268 GLTPKLL 274
>MNCP_OXYFA (P15798) Macronuclear solute carrier homolog CR-MSC| Length = 371 Score = 30.0 bits (66), Expect = 6.7 Identities = 16/49 (32%), Positives = 27/49 (55%) Frame = -3 Query: 392 AIAKLGATVVTYPLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYE 246 A+A TVV+ P ++++RL + + N Y G +D K+I+YE Sbjct: 225 AVAVAIGTVVSMPFDMIRTRLHTMRPLP-NGQMPYNGMIDCFNKIIKYE 272
>MIAA_BARQU (Q6FZ96) tRNA delta(2)-isopentenylpyrophosphate transferase (EC| 2.5.1.8) (IPP transferase) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPTase) (IPPT) Length = 295 Score = 30.0 bits (66), Expect = 6.7 Identities = 15/46 (32%), Positives = 23/46 (50%) Frame = -2 Query: 495 VYDI*NAVKASPVEAVWKAIPQEEHHCYGGIFIRCNSKAGSYCCDL 358 VYD+ N + A P EA +P H+ YG + + G + CD+ Sbjct: 40 VYDVLNILTARPTEADTAIVP---HYLYGYVSPALHYSVGQWLCDV 82
>PIC2_YEAST (P40035) Mitochondrial phosphate carrier protein 2 (Phosphate| transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2) Length = 300 Score = 29.6 bits (65), Expect = 8.8 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Frame = -3 Query: 398 LGAIAKLGATVVTY-PLLVVKSRLQAKQEIGRNAASRYTGTLDAILKMIRYEGLHGFYKG 222 LG I G T + PL +VK RLQ ++ YT L K+I EG Y G Sbjct: 23 LGGIIACGPTHSSITPLDLVKCRLQVNPKL-------YTSNLQGFRKIIANEGWKKVYTG 75 Query: 221 MGTKIV 204 G V Sbjct: 76 FGATFV 81 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 90,961,300 Number of Sequences: 219361 Number of extensions: 1776194 Number of successful extensions: 4736 Number of sequences better than 10.0: 184 Number of HSP's better than 10.0 without gapping: 4239 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4530 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6655306086 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
