ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal13g13 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 90.9 bits (224), Expect = 2e-18 Identities = 43/91 (47%), Positives = 59/91 (64%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 KPY RKVDVYSFG++LWE+ T +PF+ ++PVQ A+AVA +P P C A+ LI Sbjct: 261 KPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPAS-CQPALAHLI 319 Query: 381 EQCCALQPEKRPDFWQLVKTLEKIQSVMSQG 289 ++C + P KRPDF +V LEK + +G Sbjct: 320 KRCWSENPSKRPDFSNIVAVLEKYDECVKEG 350
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 72.0 bits (175), Expect = 1e-12 Identities = 39/111 (35%), Positives = 64/111 (57%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 +++ DV+SFG+LLWE++TG +P+ + + VAY VA +KL P CP L+ Sbjct: 299 FSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPST-CPEPFAQLMAD 357 Query: 375 CCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSSGHKKGLKHWIQKL 223 C A P +RPDF +++ LE +++ + + D+ S ++G K IQ L Sbjct: 358 CWAQDPHRRPDFASILQQLEALEAQVLREMPRDSFHSM--QEGWKREIQGL 406
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 71.6 bits (174), Expect = 1e-12 Identities = 34/83 (40%), Positives = 51/83 (61%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 +++ DV+SFG+LLWE++TG +P+ + + VAY VA +KL P CP L+E+ Sbjct: 280 FSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPST-CPEPFARLLEE 338 Query: 375 CCALQPEKRPDFWQLVKTLEKIQ 307 C P RPDF ++K LE I+ Sbjct: 339 CWDPDPHGRPDFGSILKRLEVIE 361
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 70.1 bits (170), Expect = 4e-12 Identities = 33/82 (40%), Positives = 50/82 (60%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 Y++ DV+S+G+LLWE++TG P++ P+ VAY VA + L P+ CP L++ Sbjct: 322 YSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKT-CPETWGALMKS 380 Query: 375 CCALQPEKRPDFWQLVKTLEKI 310 C P KRP F +++K LE I Sbjct: 381 CWQTDPHKRPGFKEILKQLESI 402
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 67.0 bits (162), Expect = 3e-11 Identities = 34/82 (41%), Positives = 49/82 (59%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 Y+ KVDVY F L++WE++TG IPF +L Q + VA L+P P +YC ++ L+ Q Sbjct: 287 YSEKVDVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIP-EYCDPELKLLLTQ 345 Query: 375 CCALQPEKRPDFWQLVKTLEKI 310 C P RP F +V L++I Sbjct: 346 CWEADPNDRPPFTYIVNKLKEI 367
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 65.9 bits (159), Expect = 8e-11 Identities = 38/112 (33%), Positives = 59/112 (52%), Gaps = 2/112 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 +++ DV+S+G+LLWE++TG +PF + + VAY VA +KL P CP L+E Sbjct: 326 FSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPST-CPEPFAKLMED 384 Query: 375 CCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSSGH--KKGLKHWIQK 226 C P RP F ++ L I+ + G + + S H + KH IQ+ Sbjct: 385 CWNPDPHSRPSFTNILDQLTTIE----ESGFFEMPKDSFHCLQDNWKHEIQE 432
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 64.3 bits (155), Expect = 2e-10 Identities = 30/85 (35%), Positives = 49/85 (57%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 P + D YS+G++LWEM+T +PF+ L +QVA+ V +K + + CP + L+ Sbjct: 182 PVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLV-VEKNERLTIPSSCPRSFAELLH 240 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQS 304 QC +KRP F Q++ LE + + Sbjct: 241 QCWEADAKKRPSFKQIISILESMSN 265
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 64.3 bits (155), Expect = 2e-10 Identities = 30/85 (35%), Positives = 49/85 (57%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 P + D YS+G++LWEM+T +PF+ L +QVA+ V +K + + CP + L+ Sbjct: 182 PVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLV-VEKNERLTIPSSCPRSFAELLH 240 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQS 304 QC +KRP F Q++ LE + + Sbjct: 241 QCWEADAKKRPSFKQIISILESMSN 265
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 63.2 bits (152), Expect = 5e-10 Identities = 28/82 (34%), Positives = 50/82 (60%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +P + KVD++SFG++LWE++TG IP++++ + + V ++ L P CP + L+ Sbjct: 285 EPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSS-CPDGFKILL 343 Query: 381 EQCCALQPEKRPDFWQLVKTLE 316 QC +P RP F Q++ L+ Sbjct: 344 RQCWNSKPRNRPSFRQILLHLD 365
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 63.2 bits (152), Expect = 5e-10 Identities = 28/82 (34%), Positives = 50/82 (60%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +P + KVD++SFG++LWE++TG IP++++ + + V ++ L P CP + L+ Sbjct: 318 EPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSS-CPDGFKILL 376 Query: 381 EQCCALQPEKRPDFWQLVKTLE 316 QC +P RP F Q++ L+ Sbjct: 377 RQCWNRKPRNRPSFRQILLHLD 398
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 63.2 bits (152), Expect = 5e-10 Identities = 28/82 (34%), Positives = 50/82 (60%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +P + KVD++SFG++LWE++TG IP++++ + + V ++ L P CP + L+ Sbjct: 318 EPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSS-CPDGFKILL 376 Query: 381 EQCCALQPEKRPDFWQLVKTLE 316 QC +P RP F Q++ L+ Sbjct: 377 RQCWNSKPRNRPSFRQILLHLD 398
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 62.8 bits (151), Expect = 6e-10 Identities = 32/81 (39%), Positives = 48/81 (59%) Frame = -1 Query: 549 RKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 R D++SF +LLWE+VT +PF +LS +++ VA + L+P P P + L++ C Sbjct: 371 RSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTVPPGISPHVCK-LMKICM 429 Query: 369 ALQPEKRPDFWQLVKTLEKIQ 307 P KRP F +V LEK+Q Sbjct: 430 NEDPAKRPKFDMIVPILEKMQ 450
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 62.8 bits (151), Expect = 6e-10 Identities = 32/81 (39%), Positives = 48/81 (59%) Frame = -1 Query: 549 RKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 R D++SF +LLWE+VT +PF +LS +++ VA + L+P P P + L++ C Sbjct: 371 RSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCK-LMKICM 429 Query: 369 ALQPEKRPDFWQLVKTLEKIQ 307 P KRP F +V LEK+Q Sbjct: 430 NEDPAKRPKFDMIVPILEKMQ 450
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 62.4 bits (150), Expect = 8e-10 Identities = 35/86 (40%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 K ++ K DV+SFG+LLWE+ + GR+P+ + V V +K MDP D CPA V + Sbjct: 361 KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRV--EKGYKMDPPDGCPAIVYEV 418 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQ 307 +++C L P RP F QL + L I+ Sbjct: 419 MKKCWTLDPGHRPSFHQLREQLVHIK 444
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 62.4 bits (150), Expect = 8e-10 Identities = 30/84 (35%), Positives = 48/84 (57%), Gaps = 5/84 (5%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAV-----ATDKLKPMDPQDYCPAAVR 391 Y K DVYSFG++LWE++T ++P+ +L YA+ + +KL + CP ++ Sbjct: 183 YTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIK 242 Query: 390 PLIEQCCALQPEKRPDFWQLVKTL 319 L+E C + PEKRP ++ K L Sbjct: 243 QLMECCMDINPEKRPSMKEIEKFL 266
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 61.6 bits (148), Expect = 1e-09 Identities = 28/86 (32%), Positives = 50/86 (58%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 +++ D++S+G+LLWE++TG +P+ + + VAY VA +KL P CP L+++ Sbjct: 321 FSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPST-CPEPFAKLMKE 379 Query: 375 CCALQPEKRPDFWQLVKTLEKIQSVM 298 C P RP F +++ L I+ + Sbjct: 380 CWQQDPHIRPSFALILEQLTAIEGAV 405
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 60.8 bits (146), Expect = 2e-09 Identities = 32/80 (40%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K DV+SFG+LLWE+ + GR P+ +S +V+ AV +K M+P D CP V L+ Sbjct: 361 FSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAV--EKGYRMEPPDSCPGPVHTLMG 418 Query: 378 QCCALQPEKRPDFWQLVKTL 319 C +P +RP F ++V+ L Sbjct: 419 SCWEAEPSRRPPFRKIVEKL 438
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 60.8 bits (146), Expect = 2e-09 Identities = 32/80 (40%), Positives = 51/80 (63%), Gaps = 1/80 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K DV+SFG+LLWE+ + GR P+ +S +V+ AV +K M+P D CP +V L+ Sbjct: 399 FSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAV--EKGYRMEPPDGCPGSVHTLMG 456 Query: 378 QCCALQPEKRPDFWQLVKTL 319 C +P +RP F ++V+ L Sbjct: 457 SCWEAEPARRPPFRKIVEKL 476
>ARAF_PIG (O19004) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-Raf-1) Length = 606 Score = 60.5 bits (145), Expect = 3e-09 Identities = 31/87 (35%), Positives = 53/87 (60%), Gaps = 3/87 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY++G++L+E++TG +P+ ++ S Q+ + V L P CP A+R Sbjct: 485 PYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISSNCPKAMRR 544 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQ 307 L+ C Q E+RP F Q++ T+E +Q Sbjct: 545 LLSDCLKFQREERPLFPQILATIELLQ 571
>ARAF_RAT (P14056) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 60.1 bits (144), Expect = 4e-09 Identities = 31/87 (35%), Positives = 55/87 (63%), Gaps = 3/87 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 PY+ + DVY++G++L+E++TG +P+ ++ S Q+ + V L P + + CP A+R Sbjct: 483 PYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRR 542 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQ 307 L+ C Q E+RP F Q++ T+E +Q Sbjct: 543 LLTDCLKFQREERPLFPQILATIELLQ 569
>ARAF_MOUSE (P04627) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) Length = 604 Score = 60.1 bits (144), Expect = 4e-09 Identities = 31/87 (35%), Positives = 55/87 (63%), Gaps = 3/87 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 PY+ + DVY++G++L+E++TG +P+ ++ S Q+ + V L P + + CP A+R Sbjct: 483 PYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRR 542 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQ 307 L+ C Q E+RP F Q++ T+E +Q Sbjct: 543 LLTDCLKFQREERPLFPQILATIELLQ 569
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 59.7 bits (143), Expect = 5e-09 Identities = 31/81 (38%), Positives = 47/81 (58%) Frame = -1 Query: 549 RKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 R D++SF +LLWE+VT +PF +LS +++ VA + L+P P P + L++ C Sbjct: 371 RSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCK-LMKICM 429 Query: 369 ALQPEKRPDFWQLVKTLEKIQ 307 P KR F +V LEK+Q Sbjct: 430 NEDPAKRSKFDMIVPILEKMQ 450
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 59.3 bits (142), Expect = 7e-09 Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 1/87 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + K DV+SFG+LLWE++T G P+ ++ P + + +A + P +YCP ++ +++ Sbjct: 1264 FTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQP--EYCPDSLYQVMQ 1321 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVM 298 QC P RP F LV +E+I S + Sbjct: 1322 QCWEADPAVRPTFRVLVGEVEQIVSAL 1348
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 59.3 bits (142), Expect = 7e-09 Identities = 33/84 (39%), Positives = 48/84 (57%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +P N K DVYSFG++LWE+ T + P+ NL+P QV AV + P++ P V +I Sbjct: 726 EPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNP-QVAAII 784 Query: 381 EQCCALQPEKRPDFWQLVKTLEKI 310 E C +P KRP F ++ L + Sbjct: 785 EGCWTNEPWKRPSFATIMDLLRPL 808
>ARAF_HUMAN (P10398) A-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (A-raf-1) (Proto-oncogene Pks) Length = 606 Score = 58.9 bits (141), Expect = 9e-09 Identities = 30/87 (34%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENLS-PVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY++G++L+E++TG +P+ ++ Q+ + V L P CP A+R Sbjct: 485 PYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRR 544 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQ 307 L+ C Q E+RP F Q++ T+E +Q Sbjct: 545 LLSDCLKFQREERPLFPQILATIELLQ 571
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 K ++ K DV+SFG+LLWE+ + GR+P+ + V V +K MD D CP AV + Sbjct: 361 KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRV--EKGYKMDAPDGCPPAVYDV 418 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 ++ C L RP F QL + LE I++ Sbjct: 419 MKNCSHLDAATRPTFLQLREQLEHIKT 445
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 58.5 bits (140), Expect = 1e-08 Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 K ++ K DV+SFG+LLWE+ + GR+P+ + V V +K MD D CP AV + Sbjct: 361 KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRV--EKGYKMDAPDGCPPAVYEV 418 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 ++ C L RP F QL + LE I++ Sbjct: 419 MKNCWHLDAAMRPSFLQLREQLEHIKT 445
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 58.5 bits (140), Expect = 1e-08 Identities = 27/82 (32%), Positives = 49/82 (59%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +P + KVD++SFG++LWE++TG IP++++ + + V ++ L P CP + L+ Sbjct: 328 EPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPST-CPDGFKILM 386 Query: 381 EQCCALQPEKRPDFWQLVKTLE 316 +Q +P RP F Q + L+ Sbjct: 387 KQTWQSKPRNRPSFRQTLMHLD 408
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 58.5 bits (140), Expect = 1e-08 Identities = 27/82 (32%), Positives = 49/82 (59%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +P + KVD++SFG++LWE++TG IP++++ + + V ++ L P CP + L+ Sbjct: 328 EPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPST-CPDGFKILM 386 Query: 381 EQCCALQPEKRPDFWQLVKTLE 316 +Q +P RP F Q + L+ Sbjct: 387 KQTWQSKPRNRPSFRQTLMHLD 408
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 K ++ K DV+SFG+LLWE+ + GR+P+ + V V +K MD D CP AV + Sbjct: 361 KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRV--EKGYKMDAPDGCPPAVYDV 418 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 ++ C L RP F QL + LE I++ Sbjct: 419 MKNCWHLDAATRPTFLQLREQLEHIRT 445
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/82 (37%), Positives = 49/82 (59%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + K DV+SFG+LLWE+ + GR P+ +S +V+ AV +K M+P + CP V L+ Sbjct: 401 FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAV--EKGYRMEPPEGCPGPVHVLMS 458 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C +P +RP F +L + L + Sbjct: 459 SCWEAEPARRPPFRKLAEKLAR 480
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 57.4 bits (137), Expect = 3e-08 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 1/89 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + PV+ +++ + + MD +CP + L+ Sbjct: 666 YTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHR-MDRPPHCPPELYGLMR 723 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 +C P +RP F QLV+ L+K+ +S+ Sbjct: 724 ECWHAAPSQRPTFKQLVEALDKVLLAVSE 752
>ILK_CAVPO (P57044) Integrin-linked protein kinase (EC 2.7.11.1)| (Beta-integrin-linked kinase) Length = 451 Score = 56.6 bits (135), Expect = 5e-08 Identities = 31/81 (38%), Positives = 47/81 (58%) Frame = -1 Query: 549 RKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 R D++SF +LLWE+VT +PF +LS +++ VA + +P P P + L++ C Sbjct: 371 RSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEG-RPTIPPGISPHVCK-LMKICM 428 Query: 369 ALQPEKRPDFWQLVKTLEKIQ 307 P KRP F +V LEK+Q Sbjct: 429 NEDPAKRPKFDMIVPILEKMQ 449
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/84 (32%), Positives = 54/84 (64%), Gaps = 3/84 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY+FG++L+E++TG++P+ N+ + Q+ + V L P + CP A++ Sbjct: 258 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKR 317 Query: 387 LIEQCCALQPEKRPDFWQLVKTLE 316 L+ +C + ++RP F Q++ ++E Sbjct: 318 LMAECLKKKRDERPLFPQILASIE 341
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/84 (32%), Positives = 54/84 (64%), Gaps = 3/84 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY+FG++L+E++TG++P+ N+ + Q+ + V L P + CP A++ Sbjct: 632 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKR 691 Query: 387 LIEQCCALQPEKRPDFWQLVKTLE 316 L+ +C + ++RP F Q++ ++E Sbjct: 692 LMAECLKKKRDERPLFPQILASIE 715
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/84 (32%), Positives = 54/84 (64%), Gaps = 3/84 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY+FG++L+E++TG++P+ N+ + Q+ + V L P + CP A++ Sbjct: 672 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKR 731 Query: 387 LIEQCCALQPEKRPDFWQLVKTLE 316 L+ +C + ++RP F Q++ ++E Sbjct: 732 LMAECLKKKRDERPLFPQILASIE 755
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/84 (32%), Positives = 54/84 (64%), Gaps = 3/84 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY+FG++L+E++TG++P+ N+ + Q+ + V L P + CP A++ Sbjct: 194 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKR 253 Query: 387 LIEQCCALQPEKRPDFWQLVKTLE 316 L+ +C + ++RP F Q++ ++E Sbjct: 254 LMAECLKKKRDERPLFPQILASIE 277
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/84 (32%), Positives = 54/84 (64%), Gaps = 3/84 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY+FG++L+E++TG++P+ N+ + Q+ + V L P + CP A++ Sbjct: 672 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKR 731 Query: 387 LIEQCCALQPEKRPDFWQLVKTLE 316 L+ +C + ++RP F Q++ ++E Sbjct: 732 LMAECLKKKRDERPLFPQILASIE 755
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 56.2 bits (134), Expect = 6e-08 Identities = 27/84 (32%), Positives = 54/84 (64%), Gaps = 3/84 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY+FG++L+E++TG++P+ N+ + Q+ + V L P + CP A++ Sbjct: 242 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKR 301 Query: 387 LIEQCCALQPEKRPDFWQLVKTLE 316 L+ +C + ++RP F Q++ ++E Sbjct: 302 LMAECLKKKRDERPLFPQILASIE 325
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 55.8 bits (133), Expect = 8e-08 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G P+ NLS Q V P + CP AV L+E Sbjct: 737 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCP--ELCPDAVFRLME 794 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQ 307 QC A +P +RP F + + L+ I+ Sbjct: 795 QCWAYEPGQRPSFSTIYQELQSIR 818
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 55.8 bits (133), Expect = 8e-08 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G P+ NLS Q V P + CP AV L+E Sbjct: 735 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCP--ELCPDAVFRLME 792 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQ 307 QC A +P +RP F + + L+ I+ Sbjct: 793 QCWAYEPGQRPSFSAIYQELQSIR 816
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 55.8 bits (133), Expect = 8e-08 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G P+ NLS Q V P + CP AV L+E Sbjct: 524 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCP--ELCPDAVFRLME 581 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQ 307 QC A +P +RP F + + L+ I+ Sbjct: 582 QCWAYEPGQRPSFSAIYQELQSIR 605
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 55.1 bits (131), Expect = 1e-07 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDY-CPAAVRPLIE 379 Y K DV+S+ L LWE++TG IPF +L P A +A ++P P Y P + L+ Sbjct: 641 YTIKADVFSYSLCLWELLTGEIPFAHLKPAAAAADMAYHHIRP--PIGYSIPKPISSLLI 698 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 + PE RP+F ++V LE+ Sbjct: 699 RGWNACPEGRPEFSEVVSKLEE 720
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/84 (39%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G P+ NLS Q V P + CP AV L+E Sbjct: 392 YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCP--ELCPDAVFRLME 449 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQ 307 QC A +P +RP F + L+ I+ Sbjct: 450 QCWAYEPGQRPSFSAFYQELQSIR 473
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 55.1 bits (131), Expect = 1e-07 Identities = 30/89 (33%), Positives = 53/89 (59%), Gaps = 1/89 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + PV+ +++ + + P + CP+ + L+ Sbjct: 664 YTHQSDVWSFGILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPN-CPSELYGLMR 721 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 +C P +RP F QLV+ L+K+ +S+ Sbjct: 722 ECWHAAPSQRPTFKQLVEALDKVLLAVSE 750
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 55.1 bits (131), Expect = 1e-07 Identities = 34/105 (32%), Positives = 54/105 (51%), Gaps = 6/105 (5%) Frame = -1 Query: 540 DVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPA---AVRPLIEQCC 370 DVYSFG++LWE++T P++ ++P +A +V D ++P + A LI+QC Sbjct: 969 DVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCW 1028 Query: 369 ALQPEKRPDFWQLVKTLEKI---QSVMSQGGSLDTLRSSGHKKGL 244 RP F +++ L I S M+ G S +L S G K + Sbjct: 1029 HSDTIIRPTFLEIMTRLSNILGDSSNMTSGTSSSSLSSGGIGKSI 1073 Score = 52.8 bits (125), Expect = 7e-07 Identities = 27/79 (34%), Positives = 48/79 (60%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 Y K DV+SFG+++WE++TG+ PF + ++V+ + + +P+ P D CP LI++ Sbjct: 1537 YCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDI-LEGGRPIIPSD-CPHEFAKLIKK 1594 Query: 375 CCALQPEKRPDFWQLVKTL 319 C + KRP ++V+ L Sbjct: 1595 CWHAKAHKRPTMTEVVQQL 1613
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + K D +SFG+LLWE+ + G +P+ + +V +AT MDP CP V ++ Sbjct: 696 FTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNR--MDPPRNCPGPVYRIMT 753 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQ 307 QC QPE RPDF + LE+IQ Sbjct: 754 QCWQHQPELRPDFGSI---LERIQ 774
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/80 (35%), Positives = 48/80 (60%), Gaps = 1/80 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K DV+SFG+L+WE+ T G +P+ L+ +V + + K K P+ CP+ + L++ Sbjct: 964 FSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEG-CPSRLTKLMQ 1022 Query: 378 QCCALQPEKRPDFWQLVKTL 319 +C A P+ RP F +L L Sbjct: 1023 RCWAPSPKDRPSFSELAAAL 1042
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 54.3 bits (129), Expect = 2e-07 Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 1/73 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G +P+ NLS Q A+ ++ ++P + CP V L++ Sbjct: 788 YSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAI--EQGVRLEPPEQCPEDVYRLMQ 845 Query: 378 QCCALQPEKRPDF 340 +C P +RP F Sbjct: 846 RCWEYDPHRRPSF 858
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 54.3 bits (129), Expect = 2e-07 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDY-CPAAVRPLIE 379 Y K DV+S+ L LWE++TG IPF +L P A +A ++P P Y P + L+ Sbjct: 743 YTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRP--PIGYSIPKPISSLLI 800 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 + PE RP+F ++V LE+ Sbjct: 801 RGWNACPEGRPEFSEVVMKLEE 822
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 54.3 bits (129), Expect = 2e-07 Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 1/73 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G +P+ NLS Q A+ ++ ++P + CP V L++ Sbjct: 448 YSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAI--EQGVRLEPPEQCPEDVYRLMQ 505 Query: 378 QCCALQPEKRPDF 340 +C P +RP F Sbjct: 506 RCWEYDPRRRPSF 518
>TXK_HUMAN (P42681) Tyrosine-protein kinase TXK (EC 2.7.10.2)| Length = 527 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/83 (36%), Positives = 52/83 (62%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ K DV+SFG+L+WE+ T G++PFEN S +QV A+ ++ + P P ++ ++ Sbjct: 443 YSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAI-SEGFRLYRPH-LAPMSIYEVMY 500 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 C +PE RP F +L++ + +I Sbjct: 501 SCWHEKPEGRPTFAELLRAVTEI 523
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 53.9 bits (128), Expect = 3e-07 Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDY-CPAAVRPLIE 379 Y K DV+S+ L LWE++ G IPF +L P A +A ++P P Y P + L+ Sbjct: 640 YTIKADVFSYALCLWELLIGEIPFAHLKPAAAAADMAYHHIRP--PIGYSIPKPISSLLM 697 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 + PE RP+F ++V+ LE+ Sbjct: 698 RGWNACPEGRPEFSEVVRKLEE 719
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 53.9 bits (128), Expect = 3e-07 Identities = 30/111 (27%), Positives = 63/111 (56%), Gaps = 6/111 (5%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 P++ + DVYS+G++L+E++TG +P+ ++ + Q+ + V P + Y CP A++ Sbjct: 524 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKR 583 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVM---SQGGSLDTLRSSGHKKGL 244 L+ C E+RP F Q++ ++E +Q + ++ S +L + H + + Sbjct: 584 LVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDI 634
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 53.9 bits (128), Expect = 3e-07 Identities = 30/111 (27%), Positives = 63/111 (56%), Gaps = 6/111 (5%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 P++ + DVYS+G++L+E++TG +P+ ++ + Q+ + V P + Y CP A++ Sbjct: 524 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKR 583 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVM---SQGGSLDTLRSSGHKKGL 244 L+ C E+RP F Q++ ++E +Q + ++ S +L + H + + Sbjct: 584 LVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDI 634
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 53.9 bits (128), Expect = 3e-07 Identities = 34/78 (43%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ ++ +V V P PQD CPA++ L+ QC Sbjct: 445 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPC-PQD-CPASLHELMLQCW 502 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 503 KKDPEERPTFEYLQAFLE 520
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 53.5 bits (127), Expect = 4e-07 Identities = 30/111 (27%), Positives = 63/111 (56%), Gaps = 6/111 (5%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 P++ + DVYS+G++L+E++TG +P+ ++ + Q+ + V P + Y CP A++ Sbjct: 524 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKR 583 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVM---SQGGSLDTLRSSGHKKGL 244 L+ C E+RP F Q++ ++E +Q + ++ S +L + H + + Sbjct: 584 LVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASHTEDI 634
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 53.5 bits (127), Expect = 4e-07 Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G P+ NL+ Q V P + CP AV L+E Sbjct: 735 YSSESDVWSFGILLWETFSLGASPYPNLTNQQTREFVEKGHRLPCP--ELCPDAVFRLME 792 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQ 307 QC A +P +RP F + + L I+ Sbjct: 793 QCWAYEPGQRPSFSIICQELHSIR 816
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 53.1 bits (126), Expect = 5e-07 Identities = 31/83 (37%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+VT G P+ + P ++ + T M+ D C + L+ Sbjct: 929 YTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR--MERPDNCSEEMYRLML 986 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 QC +P+KRP F + K LEK+ Sbjct: 987 QCWKQEPDKRPVFADISKDLEKM 1009
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 53.1 bits (126), Expect = 5e-07 Identities = 31/83 (37%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+VT G P+ + P ++ + T M+ D C + L+ Sbjct: 928 YTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR--MERPDNCSEEMYRLML 985 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 QC +P+KRP F + K LEK+ Sbjct: 986 QCWKQEPDKRPVFADISKDLEKM 1008
>RYK_HUMAN (P34925) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| Length = 604 Score = 52.8 bits (125), Expect = 7e-07 Identities = 29/82 (35%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV++FG+ LWE++T G+ P+ ++ P ++A A D + P + CP + ++ C AL Sbjct: 521 DVWAFGVTLWELMTLGQTPYVDIDPFEMA-AYLKDGYRIAQPIN-CPDELFAVMACCWAL 578 Query: 363 QPEKRPDFWQLVKTLEKIQSVM 298 PE+RP F QLV+ L + + + Sbjct: 579 DPEERPKFQQLVQCLTEFHAAL 600
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 52.8 bits (125), Expect = 7e-07 Identities = 26/83 (31%), Positives = 49/83 (59%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + K DV+SFG+LLWE++T G P+ ++ P +++ +A + P +YCP ++ ++ Sbjct: 1241 FTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQGRRLPQ--PEYCPDSLYHVML 1298 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 +C P RP F LV ++++ Sbjct: 1299 RCWEADPAARPTFRALVLEVKQV 1321
>RYK_MOUSE (Q01887) Tyrosine-protein kinase RYK precursor (EC 2.7.10.1)| (Kinase VIK) (NYK-R) (Met-related kinase) Length = 594 Score = 52.8 bits (125), Expect = 7e-07 Identities = 29/82 (35%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV++FG+ LWE++T G+ P+ ++ P ++A A D + P + CP + ++ C AL Sbjct: 511 DVWAFGVTLWELMTLGQTPYVDIDPFEMA-AYLKDGYRIAQPIN-CPDELFAVMACCWAL 568 Query: 363 QPEKRPDFWQLVKTLEKIQSVM 298 PE+RP F QLV+ L + + + Sbjct: 569 DPEERPKFQQLVQCLTEFHAAL 590
>MOS_XENLA (P12965) Serine/threonine-protein kinase mos (EC 2.7.11.1)| (pp39-mos) Length = 359 Score = 52.8 bits (125), Expect = 7e-07 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 4/96 (4%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKP-MDP---QDYCPAAV 394 +P K D+YSF + LW+MV+ +P+ V YAV L+P M P A Sbjct: 248 EPVTAKADIYSFAITLWQMVSRELPYTG-DRQCVLYAVVAYDLRPEMGPLFSHTEEGRAA 306 Query: 393 RPLIEQCCALQPEKRPDFWQLVKTLEKIQSVMSQGG 286 R +++ C A +P++RP+ QL++ LE+ + M GG Sbjct: 307 RTIVQSCWAARPQERPNAEQLLERLEQ-ECAMCTGG 341
>STE20_YEAST (Q03497) Serine/threonine-protein kinase STE20 (EC 2.7.11.1)| Length = 939 Score = 52.4 bits (124), Expect = 9e-07 Identities = 26/97 (26%), Positives = 51/97 (52%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G+++ EM+ G P+ N +P++ Y +AT+ + + ++++ + Sbjct: 789 KEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFL 848 Query: 381 EQCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLDTL 271 + C ++PE R +L+ E I + SL L Sbjct: 849 DWCLCVEPEDRASATELLHD-EYITEIAEANSSLAPL 884
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 52.4 bits (124), Expect = 9e-07 Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + K D +SFG+LLWE+ + G +P+ + S +V V + MDP CP V ++ Sbjct: 1310 FTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGR--MDPPKNCPGPVYRIMT 1367 Query: 378 QCCALQPEKRPDFWQLVKTLE 316 QC QPE RP+F +++ +E Sbjct: 1368 QCWQHQPEDRPNFAIILERIE 1388
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 52.4 bits (124), Expect = 9e-07 Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + K D +SFG+LLWE+ + G +P+ + S +V V + MDP CP V ++ Sbjct: 1306 FTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGR--MDPPKNCPGPVYRIMT 1363 Query: 378 QCCALQPEKRPDFWQLVKTLE 316 QC QPE RP+F +++ +E Sbjct: 1364 QCWQHQPEDRPNFAIILERIE 1384
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 52.0 bits (123), Expect = 1e-06 Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + K DV+SFG+L+WE++T G P+ + P +A + + P PQ CP + ++ Sbjct: 242 FTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLP-QPQP-CPDTLYGVML 299 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 C A PE+RP F LV LE++ Sbjct: 300 SCWAPTPEERPSFSGLVCELERV 322
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 52.0 bits (123), Expect = 1e-06 Identities = 29/89 (32%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SF +LLWE+ T G P+ + PV+ +++ + + P + CP+ + L+ Sbjct: 663 YTHQSDVWSFEILLWEIFTLGGSPYPGI-PVEELFSLLREGHRMERPPN-CPSELYGLMR 720 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 +C P +RP F QLV+ L+K+ +S+ Sbjct: 721 ECWHAAPSQRPTFKQLVEALDKVLLAVSE 749
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E++T GRIP+ ++ +V V P P CPA++ +EQ Sbjct: 438 KSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPG--CPASLYEAMEQTW 495 Query: 369 ALQPEKRPDFWQLVKTLE 316 L PE+RP F L LE Sbjct: 496 RLDPEERPTFEYLQSFLE 513
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 52.0 bits (123), Expect = 1e-06 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E++T GR+P+ ++ +V V P P CPA++ ++EQ Sbjct: 426 KSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPG--CPASLYEVMEQAW 483 Query: 369 ALQPEKRPDFWQLVKTLE 316 L PE+RP F L LE Sbjct: 484 RLDPEERPTFEYLQSFLE 501
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 52.0 bits (123), Expect = 1e-06 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V AV D P P D CPA + L+ +C Sbjct: 374 DVWSYGIVMWEVMSFGERPYWDMSNQDVMNAVEQDYRLP-PPMD-CPAVLHQLMLECWVK 431 Query: 363 QPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSS 262 + RP F Q+V TL+K + SL L S+ Sbjct: 432 ERNMRPRFGQIVSTLDKF---LRNAASLKVLTST 462
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/87 (29%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 P++ + DVYS+G++L+E++ G +P+ ++ + Q+ + V P + Y CP A++ Sbjct: 199 PFSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAIKR 258 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQ 307 L+ C E+RP F Q++ ++E +Q Sbjct: 259 LVADCVKKVKEERPLFPQILSSIELLQ 285
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/92 (34%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPF-ENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y K DVYSFG++ +E++TG +PF E +P V V + ++P D +CP ++ LI Sbjct: 1205 YPLKSDVYSFGMVCYEVLTGDVPFPEEKNPNNVKRMV-LEGVRP-DLPAHCPIELKALIT 1262 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGS 283 C P KRP F + + L+ ++ ++ G S Sbjct: 1263 DCWNQDPLKRPSFAVICQKLKYLKYLLMTGFS 1294
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/111 (26%), Positives = 62/111 (55%), Gaps = 6/111 (5%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 P++ + DVYS+G++L+E++ G +P+ ++ + Q+ + V P + Y CP A++ Sbjct: 524 PFSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKR 583 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVM---SQGGSLDTLRSSGHKKGL 244 L+ C E+RP F Q++ ++E +Q + ++ S +L + H + + Sbjct: 584 LVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDI 634
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 51.6 bits (122), Expect = 1e-06 Identities = 28/90 (31%), Positives = 47/90 (52%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +PYN K DV+S+G++L E++ + P + + D + M CP+ L Sbjct: 231 EPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD--CPSDFLQLT 288 Query: 381 EQCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 CC + P+ RP F ++ KTLE+I S + + Sbjct: 289 FNCCNMDPKLRPSFEEIGKTLEEIMSRLQE 318
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 51.6 bits (122), Expect = 1e-06 Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ K DV+SFG+L+WE+ T G++PFEN S +QV A+ + + P P + ++ Sbjct: 443 YSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAI-SQGFRLYRPH-LAPMTIYRVMY 500 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 C P+ RP F +L++ L +I Sbjct: 501 SCWHESPKGRPTFAELLQVLTEI 523
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG+++WE++T G P+ LS +V A+ D + P D CP+A+ L+ QC Sbjct: 799 DVWSFGIVMWEVMTYGERPYWELSNHEVMKAI-NDGFRLPTPMD-CPSAIYQLMMQCWQQ 856 Query: 363 QPEKRPDFWQLVKTLEKI 310 + +RP F +V L+K+ Sbjct: 857 ERARRPKFADIVSILDKL 874
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 51.2 bits (121), Expect = 2e-06 Identities = 26/79 (32%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV++FG+L+WE +T G+ P+ LS ++V + V + ++ + CP +R L+ +C A Sbjct: 297 DVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGGR--LESPNNCPDDIRDLMTRCWAQ 354 Query: 363 QPEKRPDFWQLVKTLEKIQ 307 P RP F+ + L++I+ Sbjct: 355 DPHNRPTFFYIQHKLQEIR 373
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 51.2 bits (121), Expect = 2e-06 Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 671 YTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHR-MDKPANCTHDLYMIMR 728 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 +C P +RP F QLV+ L+++ +V S LD Sbjct: 729 ECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLD 762
>MIL_AVIMH (P00531) Serine/threonine-protein kinase transforming protein mil| (EC 2.7.11.1) Length = 380 Score = 51.2 bits (121), Expect = 2e-06 Identities = 29/111 (26%), Positives = 62/111 (55%), Gaps = 6/111 (5%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 P++ + DVYS+G++L+E++TG +P+ ++ + Q+ + V P + Y CP A++ Sbjct: 257 PFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKR 316 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVM---SQGGSLDTLRSSGHKKGL 244 L+ C E+RP F Q++ ++ +Q + ++ S +L + H + + Sbjct: 317 LVADCLKKVREERPLFPQILSSIALLQHSLPKINRSASEPSLHRASHTEDI 367
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 51.2 bits (121), Expect = 2e-06 Identities = 26/79 (32%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV++FG+L+WE +T G+ P+ LS ++V + V + ++ + CP +R L+ +C A Sbjct: 2160 DVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGGR--LESPNNCPDDIRDLMTRCWAQ 2217 Query: 363 QPEKRPDFWQLVKTLEKIQ 307 P RP F+ + L++I+ Sbjct: 2218 DPHNRPTFFYIQHKLQEIR 2236
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 51.2 bits (121), Expect = 2e-06 Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 3/73 (4%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAV---RPL 385 Y+ KVD++S G ++ EM G+ P+ NL V + + K P P+D P R Sbjct: 1357 YSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNF 1416 Query: 384 IEQCCALQPEKRP 346 ++ C + PEKRP Sbjct: 1417 LDACFEINPEKRP 1429
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 50.8 bits (120), Expect = 3e-06 Identities = 31/78 (39%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GRIP+ ++ +V + P D CP + L+ QC Sbjct: 418 KSDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNLERGYRMPQP--DNCPQELYELMMQCW 475 Query: 369 ALQPEKRPDFWQLVKTLE 316 QPE+RP F + LE Sbjct: 476 KEQPEERPTFEYMKSVLE 493
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 50.8 bits (120), Expect = 3e-06 Identities = 32/95 (33%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT--GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 Y + DV+SFG+LLWE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 665 YTHQSDVWSFGVLLWEIFTPGGPSPYPGI-PVEELFKLLKEGHR-MDKPASCTHDLYMIM 722 Query: 381 EQCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 +C P +RP F QLV+ L++I +V S LD Sbjct: 723 RECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLD 757
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE++T G P+ LS +V A+ D + P D CP+A+ L+ QC Sbjct: 800 DVWSYGIVMWEVMTYGERPYWELSNHEVMKAI-NDGFRLPTPMD-CPSAIYQLMMQCWQQ 857 Query: 363 QPEKRPDFWQLVKTLEKI 310 + +RP F +V L+K+ Sbjct: 858 ERSRRPKFADIVSILDKL 875
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 50.8 bits (120), Expect = 3e-06 Identities = 24/71 (33%), Positives = 42/71 (59%), Gaps = 1/71 (1%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATD-KLKPMDPQDYCPAAVRPLI 382 P + + D+YSFG++L+EM TG++P++ +PV +A D + P + P A+ +I Sbjct: 185 PVDCRTDIYSFGIVLYEMATGKVPYDADTPVSIALKHIQDAAVPPNELNKDIPIALNKMI 244 Query: 381 EQCCALQPEKR 349 +C +PE R Sbjct: 245 LRCIEKKPENR 255
>RYK1_DROME (Q27324) Tyrosine-protein kinase Drl precursor (EC 2.7.10.1)| (Protein derailed) Length = 610 Score = 50.8 bits (120), Expect = 3e-06 Identities = 28/89 (31%), Positives = 50/89 (56%), Gaps = 1/89 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 YN DV+SFG+L+WEM T G++P+ + P ++ + + D + P + CP + ++ Sbjct: 522 YNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYL-KDGYRLAQPFN-CPDELFTIMA 579 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 C A P +RP F QL L + + +++ Sbjct: 580 YCWASMPAERPSFSQLQICLSEFHTQITR 608
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 50.4 bits (119), Expect = 3e-06 Identities = 30/108 (27%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+LLWE+ + G P+ + Y + D + P + P + +++ Sbjct: 864 YTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPA-FAPKNIYSIMQ 922 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSSGHKKGLKHW 235 C AL+P +RP F Q+ L+K + + L SS + L+ W Sbjct: 923 ACWALEPTRRPTFQQICSLLQKQAQEDRRVPNYTNLPSSSSSRLLRPW 970
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 50.4 bits (119), Expect = 3e-06 Identities = 29/90 (32%), Positives = 50/90 (55%), Gaps = 1/90 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFE-NLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 + Y+ KVDV+SFG++L E++ GR+ + + P + + + CP + P+ Sbjct: 524 RSYDEKVDVFSFGIVLCEII-GRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPI 582 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQSVMS 295 +CC L PEKRP F +L + LE ++ +S Sbjct: 583 TVRCCDLDPEKRPSFVKLEQWLETLRMHLS 612
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 50.4 bits (119), Expect = 3e-06 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ ++ +V V P PQD CP ++ L+ C Sbjct: 445 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPC-PQD-CPISLHELMIHCW 502 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 503 KKDPEERPTFEYLQSFLE 520
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 50.1 bits (118), Expect = 4e-06 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ D P P D CPAA+ L+ C Sbjct: 724 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLP-PPMD-CPAALHQLMLDCWQK 781 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F ++V TL+K+ Sbjct: 782 DRNSRPRFGEIVNTLDKM 799
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V AV D P P D CP A+ L+ C Sbjct: 820 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLP-PPMD-CPTALHQLMLDCWVR 877 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+K+ Sbjct: 878 DRNLRPKFSQIVNTLDKL 895
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 50.1 bits (118), Expect = 4e-06 Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ K DV+SFG+L+WE+ + G+IP+EN S +V ++T + P+ V ++ Sbjct: 540 YSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTG-FRLYKPR-LASCHVYQIMN 597 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 C +PE RP F QL+ L +I Sbjct: 598 HCWKEKPEDRPPFSQLLSQLAEI 620
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 50.1 bits (118), Expect = 4e-06 Identities = 28/90 (31%), Positives = 46/90 (51%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +PYN K DV+S+G++L E++ + P + + D + M CP L Sbjct: 231 EPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD--CPPDFLQLT 288 Query: 381 EQCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 CC + P+ RP F ++ KTLE+I S + + Sbjct: 289 FNCCNMDPKLRPSFVEIGKTLEEILSRLQE 318
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 50.1 bits (118), Expect = 4e-06 Identities = 23/82 (28%), Positives = 50/82 (60%) Frame = -1 Query: 552 NRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQC 373 + K DVYS+G++L+E++T P +++ P+++A+ A + +P P + + ++ QC Sbjct: 1483 SEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLT-TSSKWKEILTQC 1541 Query: 372 CALQPEKRPDFWQLVKTLEKIQ 307 P+ RP F Q++ L++++ Sbjct: 1542 WDSNPDSRPTFKQIIVHLKEME 1563
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V AV D P P D CP A+ L+ C Sbjct: 815 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLP-PPMD-CPTALHQLMLDCWVR 872 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+K+ Sbjct: 873 DRNLRPKFSQIVNTLDKL 890
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 50.1 bits (118), Expect = 4e-06 Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 677 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHR-MDKPSNCTNELYMMMR 734 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ S LD Sbjct: 735 DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLD 768
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 50.1 bits (118), Expect = 4e-06 Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 677 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHR-MDKPSNCTNELYMMMR 734 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ S LD Sbjct: 735 DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLD 768
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 50.1 bits (118), Expect = 4e-06 Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V AV D P P D CP A+ L+ C Sbjct: 810 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLP-PPMD-CPTALHQLMLDCWVR 867 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+K+ Sbjct: 868 DRNLRPKFAQIVNTLDKL 885
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 50.1 bits (118), Expect = 4e-06 Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 675 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHR-MDKPSNCTNELYMMMR 732 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ S LD Sbjct: 733 DCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEYLD 766
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 49.7 bits (117), Expect = 6e-06 Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 2/81 (2%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLS--PVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 Y+ K DV+S+G++LWE++T R PF+ + ++ +AV P+ P + L+ Sbjct: 206 YSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN--LPKPIESLM 263 Query: 381 EQCCALQPEKRPDFWQLVKTL 319 +C + P +RP ++VK + Sbjct: 264 TRCWSKDPSQRPSMEEIVKIM 284
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ D P P D CPAA+ L+ C Sbjct: 806 DVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP-PPMD-CPAALHQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F ++V TL+K+ Sbjct: 864 DRNSRPRFAEIVNTLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ D P P D CPAA+ L+ C Sbjct: 806 DVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP-PPMD-CPAALHQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F ++V TL+K+ Sbjct: 864 DRNSRPRFAEIVNTLDKM 881
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDFWQLVKTLEKIQSVMS 295 PE+RP F L LE +++ Sbjct: 499 RKDPEERPTFEYLQAFLEDYLGILA 523
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 49.7 bits (117), Expect = 6e-06 Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFE-NLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 + Y+ KVDV+SFG++L E++ GR+ + + P + + + CP + P+ Sbjct: 524 RSYDEKVDVFSFGIVLCEII-GRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPI 582 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQ 307 +CC L PEKRP F +L + LE ++ Sbjct: 583 TVRCCDLDPEKRPSFVKLEQWLETLR 608
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 49.7 bits (117), Expect = 6e-06 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPE--CPESLHDLMSQCW 498 Query: 369 ALQPEKRPDF 340 PE+RP F Sbjct: 499 RRDPEERPTF 508
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/94 (31%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 665 YTHQSDVWSFGVLLWEIFTLGGSPYPGI-PVEELFKLLKEGHR-MDKPANCTHDLYMIMR 722 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 +C P +RP F QLV+ L+++ ++ S LD Sbjct: 723 ECWHAVPSQRPTFKQLVEDLDRVLTMTSTDEYLD 756
>TESK2_MOUSE (Q8VCT9) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 49.7 bits (117), Expect = 6e-06 Identities = 27/86 (31%), Positives = 45/86 (52%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +PYN K DV+S+G++L E++ + P + + D + M CP+ L Sbjct: 231 EPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGD--CPSDFLQLT 288 Query: 381 EQCCALQPEKRPDFWQLVKTLEKIQS 304 CC + P+ RP F ++ KTL++I S Sbjct: 289 FNCCNMDPKLRPSFEEIGKTLKEIMS 314
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 49.7 bits (117), Expect = 6e-06 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ ++ +V V P PQD CP ++ L+ C Sbjct: 445 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPC-PQD-CPISLHELMLNCW 502 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 503 KKDPEERPTFEYLQGFLE 520
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 49.7 bits (117), Expect = 6e-06 Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G++LWE+++ G P+ +S V AV D+ + P CPAA+ L+ C Sbjct: 806 DVWSYGIVLWEVMSYGERPYSQMSNQDVIKAV--DERYRLPPPMDCPAALYQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSS 262 RP F Q+V L+K+ + GSL + S+ Sbjct: 864 DRNNRPKFEQIVSILDKL---IRNPGSLKIITSA 894
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 49.7 bits (117), Expect = 6e-06 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ ++ +V V P PQD CP ++ L+ C Sbjct: 442 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPC-PQD-CPISLHELMIHCW 499 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 500 KKDPEERPTFEYLQGFLE 517
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 49.7 bits (117), Expect = 6e-06 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ ++ +V V P PQD CP ++ L+ C Sbjct: 442 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPC-PQD-CPISLHELMIHCW 499 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 500 KKDPEERPTFEYLQGFLE 517
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 49.7 bits (117), Expect = 6e-06 Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 2/81 (2%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLS--PVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 Y+ K DV+S+G++LWE++T R PF+ + ++ +AV P+ P + L+ Sbjct: 206 YSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKN--LPKPIESLM 263 Query: 381 EQCCALQPEKRPDFWQLVKTL 319 +C + P +RP ++VK + Sbjct: 264 TRCWSKDPSQRPSMEEIVKIM 284
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 444 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 501 Query: 369 ALQPEKRPDFWQLVKTLE 316 +PE+RP F L LE Sbjct: 502 RKEPEERPTFEYLQAFLE 519
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 444 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 501 Query: 369 ALQPEKRPDFWQLVKTLE 316 +PE+RP F L LE Sbjct: 502 RKEPEERPTFEYLQAFLE 519
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 49.7 bits (117), Expect = 6e-06 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 449 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 506 Query: 369 ALQPEKRPDFWQLVKTLE 316 +PE+RP F L LE Sbjct: 507 RKEPEERPTFEYLQAFLE 524
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 49.3 bits (116), Expect = 7e-06 Identities = 30/94 (31%), Positives = 52/94 (55%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P+ + P++ + + + + MD C + +++ Sbjct: 671 YTHQSDVWSFGVLLWEIFTLGGSPYPGV-PMEELFKLLKEGHR-MDKPTNCTNELYMMMK 728 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ S LD Sbjct: 729 DCWHAMPSQRPTFNQLVEDLDRILALSSNQEYLD 762
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 49.3 bits (116), Expect = 7e-06 Identities = 26/77 (33%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+ T P++ LS QV V L +D D CP + L+ C Sbjct: 1194 DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGL--LDKPDNCPDMLFELMRMCWQY 1251 Query: 363 QPEKRPDFWQLVKTLEK 313 P+ RP F +++ ++++ Sbjct: 1252 NPKMRPSFLEIISSIKE 1268
>PAK1_HUMAN (Q13153) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) Length = 545 Score = 49.3 bits (116), Expect = 7e-06 Identities = 23/79 (29%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EM+ G P+ N +P++ Y +AT+ + + A R + Sbjct: 439 KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFL 498 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + EKR +L++ Sbjct: 499 NRCLEMDVEKRGSAKELLQ 517
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 49.3 bits (116), Expect = 7e-06 Identities = 30/78 (38%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+++ GR+P+ ++ +V V P P CPA++ +EQ Sbjct: 461 KSDVWSFGILLTELISKGRVPYPGMNNREVLEQVEHGYHMPCPPG--CPASLYEAMEQTW 518 Query: 369 ALQPEKRPDFWQLVKTLE 316 L PE+RP F L LE Sbjct: 519 RLDPEERPTFEYLQSFLE 536
>PAK1_RAT (P35465) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P68-PAK) (Alpha-PAK) (Protein kinase MUK2) Length = 544 Score = 49.3 bits (116), Expect = 7e-06 Identities = 23/79 (29%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EM+ G P+ N +P++ Y +AT+ + + A R + Sbjct: 438 KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFL 497 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + EKR +L++ Sbjct: 498 NRCLEMDVEKRGSAKELLQ 516
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 499 RKDPEERPTFEYLQAFLE 516
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 D++SFG++LWE+ + P++ LS QV V +DP D CP + L+ C Sbjct: 1219 DMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGY--LDPPDNCPERLTDLMRMCWQF 1276 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F ++V L+ Sbjct: 1277 NPKMRPTFLEIVNLLK 1292
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 48.9 bits (115), Expect = 1e-05 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFE-NLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 + Y+ KVDV+SFG++L E++ GR+ + + P + + + CP + P+ Sbjct: 524 RSYDEKVDVFSFGIVLCEII-GRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPI 582 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQ 307 +CC L PEKRP F +L LE ++ Sbjct: 583 TVRCCDLDPEKRPSFVKLEHWLETLR 608
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 D++SFG++LWE+ + P++ LS QV V +DP D CP + L+ C Sbjct: 1208 DMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGY--LDPPDNCPERLTDLMRMCWQF 1265 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F ++V L+ Sbjct: 1266 NPKMRPTFLEIVNLLK 1281
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GRIP+ +S +V A+ P D CP + ++ +C Sbjct: 413 KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPR--PDNCPEELYSIMIRCW 470 Query: 369 ALQPEKRPDFWQLVKTLEKIQSVM 298 +PE+RP T E IQSV+ Sbjct: 471 KNRPEERP-------TFEYIQSVL 487
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/78 (34%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ +++ V A+ D P P D CP+A+ L+ C Sbjct: 816 DVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP-PPMD-CPSALHQLMLDCWQK 873 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+K+ Sbjct: 874 DRNHRPKFGQIVNTLDKM 891
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 499 RKDPEERPTFEYLQAFLE 516
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/83 (34%), Positives = 49/83 (59%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ K DV+SFG+L+WE+ + G+IP+EN S +V ++T + P+ V ++ Sbjct: 535 YSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTG-FRLYKPR-LASTHVYQIMN 592 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 C +PE RP F +L++ L +I Sbjct: 593 HCWKERPEDRPAFSRLLRQLAEI 615
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 48.9 bits (115), Expect = 1e-05 Identities = 27/78 (34%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ +++ V A+ D P P D CP+A+ L+ C Sbjct: 808 DVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP-PPMD-CPSALHQLMLDCWQK 865 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+K+ Sbjct: 866 DRNHRPKFGQIVNTLDKM 883
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 499 RKDPEERPTFEYLQAFLE 516
>LIMK2_HUMAN (P53671) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 48.5 bits (114), Expect = 1e-05 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 4/96 (4%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVAT----DKLKPMDPQDYCPAAV 394 K Y+ VD++SFG++L E++ + P + + + +K P D CP A Sbjct: 521 KSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTD----CPPAF 576 Query: 393 RPLIEQCCALQPEKRPDFWQLVKTLEKIQSVMSQGG 286 PL CC L+PE RP F +L + E + + + G Sbjct: 577 FPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELG 612
>PAK1_MOUSE (O88643) Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1)| (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A) Length = 545 Score = 48.5 bits (114), Expect = 1e-05 Identities = 23/79 (29%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EM+ G P+ N +P++ Y +AT+ + + A R + Sbjct: 439 KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFL 498 Query: 381 EQCCALQPEKRPDFWQLVK 325 + C + EKR +L++ Sbjct: 499 QCCLEMDVEKRGSAKELLQ 517
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 48.5 bits (114), Expect = 1e-05 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+ T P++ LS QV V L +D D CP + L+ C Sbjct: 467 DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGL--LDKPDNCPDMLFELMRMCWQY 524 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F +++ +++ Sbjct: 525 NPKMRPSFLEIISSVK 540
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P CP ++ L+ QC Sbjct: 440 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPD--CPESLHDLMFQCW 497 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 498 RKDPEERPTFEYLQAFLE 515
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 48.5 bits (114), Expect = 1e-05 Identities = 30/78 (38%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P CP ++ L+ QC Sbjct: 440 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPD--CPESLHDLMFQCW 497 Query: 369 ALQPEKRPDFWQLVKTLE 316 PE+RP F L LE Sbjct: 498 RKDPEERPTFEYLQAFLE 515
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 48.5 bits (114), Expect = 1e-05 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GRIP+ +S +V A+ P D CP + ++ +C Sbjct: 434 KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPR--PDNCPEELYNIMIRCW 491 Query: 369 ALQPEKRPDFWQLVKTLEKIQSVM 298 +PE+RP T E IQSV+ Sbjct: 492 KNRPEERP-------TFEYIQSVL 508
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 48.1 bits (113), Expect = 2e-05 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFE-NLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 + Y+ KVD++SFG++L E++ GR+ + + P + + CP + P+ Sbjct: 531 RSYDEKVDIFSFGIVLCEII-GRVSADPDYLPRTTDFGLNVRGFLERYCPPACPPSFFPI 589 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQ 307 CC L PEKRP F +L + LE ++ Sbjct: 590 AACCCDLDPEKRPSFSKLEQWLETLR 615
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G++LWE+++ G P+ +S V AV P+ P D CPAA+ L+ C Sbjct: 807 DVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPL-PMD-CPAALYQLMLDCWQK 864 Query: 363 QPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSS 262 RP F Q+V L+K+ + GSL + S+ Sbjct: 865 DRNNRPKFEQIVSILDKL---IRNPGSLKIITSA 895
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+ T P++ LS QV V L +D D CP + L+ C Sbjct: 1196 DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGL--LDKPDNCPDMLFELMRMCWQY 1253 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F +++ +++ Sbjct: 1254 NPKMRPSFLEIIGSIK 1269
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/94 (30%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+L+WE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 682 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHR-MDKPANCTNELYMMMR 739 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ + LD Sbjct: 740 DCWQAVPSQRPTFKQLVEDLDRILTLTTNEEYLD 773
>LIMK2_RAT (P53670) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVAT----DKLKPMDPQDYCPAAV 394 K Y+ VDV+SFG++L E++ + P + + + +K P D CP A Sbjct: 521 KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTD----CPPAF 576 Query: 393 RPLIEQCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 PL CC L+PE RP F +L + E + + + Sbjct: 577 FPLAAICCKLEPESRPAFSKLEDSFEALSLFLGE 610
>LIMK2_MOUSE (O54785) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVAT----DKLKPMDPQDYCPAAV 394 K Y+ VDV+SFG++L E++ + P + + + +K P D CP A Sbjct: 521 KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTD----CPPAF 576 Query: 393 RPLIEQCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 PL CC L+PE RP F +L + E + + + Sbjct: 577 FPLAAICCKLEPESRPAFSKLEDSFEALSLFLGE 610
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.1 bits (113), Expect = 2e-05 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDF 340 PE+RP F Sbjct: 499 RRDPEERPTF 508
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 48.1 bits (113), Expect = 2e-05 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDF 340 PE+RP F Sbjct: 499 RRDPEERPTF 508
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/94 (30%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+L+WE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 680 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHR-MDKPTNCTNELYMMMR 737 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ + LD Sbjct: 738 DCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLD 771
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+VT P++ LS QV V + ++ + CP ++ L+ C Sbjct: 1174 DVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGV--LEELEDCPHQLQELMSSCWQQ 1231 Query: 363 QPEKRPDFWQLVKTLEK 313 P RP F Q++ +++K Sbjct: 1232 NPRLRPTFTQILNSIQK 1248
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+ T P++ LS QV V L +D D CP + L+ C Sbjct: 1195 DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGL--LDKPDNCPDMLFELMRMCWQY 1252 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F +++ +++ Sbjct: 1253 NPKMRPSFLEIIGSIK 1268
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 48.1 bits (113), Expect = 2e-05 Identities = 27/78 (34%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ D P P D CP+A+ L+ C Sbjct: 796 DVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLP-PPMD-CPSALHQLMLDCWLR 853 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V +L+K+ Sbjct: 854 DRNLRPKFSQIVSSLDKL 871
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 9/94 (9%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WEMVT P++ LS +V ++ + M+ + CP + L++ C A Sbjct: 1232 DVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFISDGYI--MELPENCPNEMAYLMQHCWAK 1289 Query: 363 QPEKRPDFWQLVKTL--------EKIQSVMSQGG 286 +P +RP F +++ L EK+ + GG Sbjct: 1290 KPNQRPTFKAIIEYLLPKLKPSFEKVSYFFTSGG 1323
>PAK2_RAT (Q64303) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p62-PAK) Length = 524 Score = 47.8 bits (112), Expect = 2e-05 Identities = 23/79 (29%), Positives = 41/79 (51%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + R + Sbjct: 418 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFL 477 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + EKR +L++ Sbjct: 478 NRCLEMDVEKRGSAKELLQ 496
>PAK2_RABIT (Q29502) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (Gamma-PAK) (p21-activated protein kinase I) (PAKI) Length = 524 Score = 47.8 bits (112), Expect = 2e-05 Identities = 23/79 (29%), Positives = 41/79 (51%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + R + Sbjct: 418 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFL 477 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + EKR +L++ Sbjct: 478 NRCLEMDVEKRGSAKELLQ 496
>PAK2_MOUSE (Q8CIN4) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) Length = 524 Score = 47.8 bits (112), Expect = 2e-05 Identities = 23/79 (29%), Positives = 41/79 (51%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + R + Sbjct: 418 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFL 477 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + EKR +L++ Sbjct: 478 NRCLEMDVEKRGSAKELLQ 496
>PAK2_HUMAN (Q13177) Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1)| (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase) Length = 524 Score = 47.8 bits (112), Expect = 2e-05 Identities = 23/79 (29%), Positives = 41/79 (51%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + R + Sbjct: 418 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFL 477 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + EKR +L++ Sbjct: 478 NRCLEMDVEKRGSAKELLQ 496
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 + + DV+SFG+L+WE++T G P+ S + V V T ++P CP + L+ Sbjct: 2138 FTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGR--LEPPRNCPDDLWNLMT 2195 Query: 378 QCCALQPEKRPDFWQLVKTLE 316 QC A +P++RP F ++ L+ Sbjct: 2196 QCWAQEPDQRPTFHRIQNQLQ 2216
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ +++ V A+ D P P D CP A+ L+ C Sbjct: 809 DVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP-PPMD-CPNALHQLMLDCWQK 866 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+K+ Sbjct: 867 DRNHRPKFGQIVNTLDKM 884
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/84 (38%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GRIP+ +S +V A+ ++ M + CP + ++ +C Sbjct: 414 KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL--ERGYRMPRPENCPEELYNIMMRCW 471 Query: 369 ALQPEKRPDFWQLVKTLEKIQSVM 298 +PE+RP T E IQSV+ Sbjct: 472 KNRPEERP-------TFEYIQSVL 488
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 47.8 bits (112), Expect = 2e-05 Identities = 29/78 (37%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ ++ +V V ++ M CP ++ ++ QC Sbjct: 444 KSDVWSFGILLTELVTKGRVPYPGMNNREVLEQV--ERGYRMQCPGGCPPSLHDVMVQCW 501 Query: 369 ALQPEKRPDFWQLVKTLE 316 +PE+RP F L LE Sbjct: 502 KREPEERPTFEYLQSFLE 519
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 47.8 bits (112), Expect = 2e-05 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+LLWE+ + G P+ + Y + D + P + P + +++ Sbjct: 830 YTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPA-FAPKNIYSIMQ 888 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C AL+P +RP F Q+ L+K Sbjct: 889 ACWALEPTRRPTFQQICSLLQK 910
>RAF1_XENLA (P09560) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (C-RAF) Length = 638 Score = 47.8 bits (112), Expect = 2e-05 Identities = 25/87 (28%), Positives = 52/87 (59%), Gaps = 3/87 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENL-SPVQVAYAVATDKLKPMDPQDY--CPAAVRP 388 P++ + DVYS+G++L+E++TG +P+ ++ Q+ + V + P + Y CP A++ Sbjct: 515 PFSFQSDVYSYGIVLYELMTGELPYSHIRDRDQIIFLVGRGGVVPDLSKLYKNCPKAMKR 574 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQ 307 L+ ++RP F Q++ ++E +Q Sbjct: 575 LVADSIKKLRDERPLFPQILSSIELLQ 601
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 47.8 bits (112), Expect = 2e-05 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+LLWE+ T G P + PV+ + + + + MD C + ++ Sbjct: 677 YTHQSDVWSFGVLLWEIFTLGGSPNPGV-PVEELFKLLKEGHR-MDKPSNCTNELYMMMR 734 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ S LD Sbjct: 735 DCWNAVPSQRPTFKQLVEDLDRIVALTSNQEYLD 768
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 47.8 bits (112), Expect = 2e-05 Identities = 28/87 (32%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 + K DV+SFG+LLWE++T G P+ +++ + + + L+P +YCP A+ + Sbjct: 1258 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLLQP----EYCPDALYEV 1313 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 + +C + E RP F +LV + I S Sbjct: 1314 MLKCWHPKAEMRPSFSELVSRISSIFS 1340
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/84 (38%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GRIP+ +S +V A+ ++ M + CP + ++ +C Sbjct: 436 KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL--ERGYRMPRPENCPEELYNIMMRCW 493 Query: 369 ALQPEKRPDFWQLVKTLEKIQSVM 298 +PE+RP T E IQSV+ Sbjct: 494 KNRPEERP-------TFEYIQSVL 510
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 47.8 bits (112), Expect = 2e-05 Identities = 29/94 (30%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+L+WE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 680 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHR-MDKPANCTNELYMMMR 737 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P +RP F QLV+ L++I ++ + LD Sbjct: 738 DCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLD 771
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 47.8 bits (112), Expect = 2e-05 Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 1/94 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G++LWE+++ G P+ +S V AV D+ + P CPAA+ L+ C Sbjct: 806 DVWSYGIVLWEVMSYGERPYWEMSNQDVIKAV--DEGYRLPPPMDCPAALYQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSS 262 RP F Q+V L+K+ + GSL + S+ Sbjct: 864 DRNNRPKFEQIVSILDKL---IRNPGSLKIITSA 894
>PAK3_RAT (Q62829) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (p65-PAK) Length = 544 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/79 (27%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + A R + Sbjct: 437 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFL 496 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + ++R +L++ Sbjct: 497 NRCLEMDVDRRGSAKELLQ 515
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 47.8 bits (112), Expect = 2e-05 Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 15/124 (12%) Frame = -1 Query: 552 NRKVDVYSFGLLLWEMVTGRIPFENLS----PVQVAYAVATDKLKPMDPQDYCPAA---- 397 ++K DVYSFG++ E++ R F LS ++ D LKP P + A Sbjct: 661 SQKGDVYSFGIIAQEIIMRRETFYTLSCRDQKEKIFRVEHPDGLKPFRPDLFLETAEEKE 720 Query: 396 --VRPLIEQCCALQPEKRPDFWQLVKTLEKIQSV---MSQGGSLDTL--RSSGHKKGLKH 238 V L++ C PEKRPDF ++ TL KI + +DTL R + + L+H Sbjct: 721 LEVFLLVKNCWEEDPEKRPDFKKIENTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEH 780 Query: 237 WIQK 226 +++ Sbjct: 781 LVEE 784
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 47.8 bits (112), Expect = 2e-05 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ +++ V A+ D P P D CP A+ L+ C Sbjct: 826 DVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLP-PPMD-CPNALHQLMLDCWQK 883 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+K+ Sbjct: 884 DRNHRPKFGQIVNTLDKM 901
>PAK3_PONPY (Q7YQL3) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/79 (27%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + A R + Sbjct: 452 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFL 511 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + ++R +L++ Sbjct: 512 NRCLEMDVDRRGSAKELLQ 530
>PAK3_PANTR (Q7YQL4) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) Length = 559 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/79 (27%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + A R + Sbjct: 452 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFL 511 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + ++R +L++ Sbjct: 512 NRCLEMDVDRRGSAKELLQ 530
>PAK3_MOUSE (Q61036) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B) Length = 559 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/79 (27%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + A R + Sbjct: 452 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFL 511 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + ++R +L++ Sbjct: 512 NRCLEMDVDRRGSAKELLQ 530
>PAK3_HUMAN (O75914) Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1)| (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3) Length = 559 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/79 (27%), Positives = 42/79 (53%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVD++S G++ EMV G P+ N +P++ Y +AT+ + + A R + Sbjct: 452 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFL 511 Query: 381 EQCCALQPEKRPDFWQLVK 325 +C + ++R +L++ Sbjct: 512 NRCLEMDVDRRGSAKELLQ 530
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 47.4 bits (111), Expect = 3e-05 Identities = 28/85 (32%), Positives = 49/85 (57%), Gaps = 3/85 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 ++ K DV+SFG+L+WE+ T GR+PFE + +V V +P +Y V + Sbjct: 542 FSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNY----VYEV 597 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKI 310 + +C +PE RP F L++T++++ Sbjct: 598 MLRCWQEKPEGRPSFEDLLRTIDEL 622
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ LWE+ + G P+ + Y + + + + P+ + PA + +++ Sbjct: 284 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE-HAPAEMYDIMK 342 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C P KRP F Q+V+ +EK Sbjct: 343 TCWDADPLKRPTFKQIVQLIEK 364
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ LWE+ + G P+ + Y + + + + P+ + PA + +++ Sbjct: 845 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE-HAPAEMYDIMK 903 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C P KRP F Q+V+ +EK Sbjct: 904 TCWDADPLKRPTFKQIVQLIEK 925
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 47.4 bits (111), Expect = 3e-05 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 K Y+ K DV+S+G+LLWE++T G+ P+ + + Y + M+ C + L Sbjct: 608 KFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQR-MEKPAKCSMNIYIL 666 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKI 310 + QC + RP F ++V+ ++K+ Sbjct: 667 MRQCWHFNADDRPPFTEIVEYMDKL 691
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 47.4 bits (111), Expect = 3e-05 Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ +S +V + P P P R +I +C Sbjct: 414 KADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPR-PDTCPPELYRGVIAECW 472 Query: 369 ALQPEKRPDFWQLVKTLE 316 +PE+RP F L LE Sbjct: 473 RSRPEERPTFEFLQSVLE 490
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ LWE+ + G P+ + Y + + + + P+ + PA + +++ Sbjct: 847 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE-HAPAEMYDIMK 905 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C P KRP F Q+V+ +EK Sbjct: 906 TCWDADPLKRPTFKQIVQLIEK 927
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ LWE+ + G P+ + Y + + + + P+ + PA + +++ Sbjct: 848 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE-HAPAEMYDIMK 906 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C P KRP F Q+V+ +EK Sbjct: 907 TCWDADPLKRPTFKQIVQLIEK 928
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.4 bits (111), Expect = 3e-05 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDF 340 PE+RP F Sbjct: 499 RKDPEERPTF 508
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ + +V V P PQ CP ++ ++ QC Sbjct: 452 KSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGYRMPC-PQG-CPESLHEMMRQCW 509 Query: 369 ALQPEKRPDFWQLVKTLE 316 +P++RP F + LE Sbjct: 510 KKEPDERPTFEYIQSFLE 527
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 47.4 bits (111), Expect = 3e-05 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 438 KSDVWSFGILLTELTTKGRVPYPGMVNGEVLDRVERGYRMPCPPE--CPESLHDLMCQCW 495 Query: 369 ALQPEKRPDF 340 PE+RP F Sbjct: 496 RKDPEERPTF 505
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ LWE+ + G P+ + Y + + + + P+ + PA + +++ Sbjct: 847 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE-HAPAEMYDIMK 905 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C P KRP F Q+V+ +EK Sbjct: 906 TCWDADPLKRPTFKQIVQLIEK 927
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 47.4 bits (111), Expect = 3e-05 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 3/86 (3%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENLS-PVQVAYAVATDKLKP--MDPQDYCPAAVRP 388 PY+ + DVY+FG++++E++ +P+ ++S Q+ + V L+P + P A++ Sbjct: 604 PYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKR 663 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKI 310 L E C P+ RP F L+ LE + Sbjct: 664 LAEDCIKYTPKDRPLFRPLLNMLENM 689
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ LWE+ + G P+ + Y + + + + P+ + PA + +++ Sbjct: 846 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPE-HAPAEMYDIMK 904 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C P KRP F Q+V+ +EK Sbjct: 905 TCWDADPLKRPTFKQIVQLIEK 926
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ D P P D CPAA+ L+ C Sbjct: 806 DVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP-PPMD-CPAALHQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP ++V TL+K+ Sbjct: 864 DRNTRPRLAEIVNTLDKM 881
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQ--DYCPAAVRPLIEQC 373 K DVYSFG++LW + + P+EN+ + +P + +YCP + L+E+C Sbjct: 209 KSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERC 268 Query: 372 CALQPEKRPDF 340 PE RP F Sbjct: 269 WQAIPEDRPTF 279
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 47.0 bits (110), Expect = 4e-05 Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 4/93 (4%) Frame = -1 Query: 555 YNR---KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRP 388 YNR K DV+SFG+L+ E+VT GR+P+ ++ QV AV D+ M + CP + Sbjct: 236 YNRFTIKSDVWSFGVLISEIVTHGRMPYPGMTNRQVLEAV--DRGYRMPCPEGCPDPLYK 293 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVMSQG 289 ++ C +P+ RP F L LE ++G Sbjct: 294 IMLSCWKHEPDDRPTFESLKNLLEDYYVSAAEG 326
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 1/84 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ + DV+SFG+LLWE + G P+ ++ Q V ++ M +CP + ++ Sbjct: 737 YSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQV--ERGYRMSAPQHCPEDISKIMM 794 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQ 307 +C +PE RP F +L K L I+ Sbjct: 795 KCWDYKPENRPKFSELQKELTIIK 818
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+ T GR+P+ + +V V P P+ CP ++ L+ QC Sbjct: 441 KSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERAYRMPCPPE--CPESLHDLMCQCW 498 Query: 369 ALQPEKRPDF 340 PE+RP F Sbjct: 499 RKDPEERPTF 508
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 47.0 bits (110), Expect = 4e-05 Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+ T P++ +S QV V L ++ D CP + L+ C Sbjct: 1190 DVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGL--LEKPDNCPDMLFELMRMCWQF 1247 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F +++ +++ Sbjct: 1248 NPKMRPSFLEIISSIK 1263
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 2/82 (2%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVA-YAVATDKLKPMDPQDYCPAAVRPLI 382 + K D +SFG+LLWE+ + G +P+ + +V + V + MDP CP V ++ Sbjct: 700 FTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGR---MDPPRGCPGPVYRIM 756 Query: 381 EQCCALQPEKRPDFWQLVKTLE 316 QC +PE RP F +++ L+ Sbjct: 757 TQCWQHEPELRPSFASILERLQ 778
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 47.0 bits (110), Expect = 4e-05 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 D++SFG++LWE+ + P++ LS QV V +D D CP V L+ C Sbjct: 1218 DMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGY--LDQPDNCPERVTDLMRMCWQF 1275 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F ++V L+ Sbjct: 1276 NPKMRPTFLEIVNLLK 1291
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 46.6 bits (109), Expect = 5e-05 Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 18/125 (14%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+V+ G P+ ++ V AV P P D CPAA+ L+ C Sbjct: 699 DVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLP-SPMD-CPAALYQLMLDCWQK 756 Query: 363 QPEKRPDFWQLVKTLEK-----------------IQSVMSQGGSLDTLRSSGHKKGLKHW 235 RP F ++V L+K + +++++ GSL SG + + W Sbjct: 757 DRNSRPKFDEIVNMLDKLIRNPSSLKTLVNASSRVSTLLAEHGSL----GSGAYRSVGEW 812 Query: 234 IQKLK 220 ++ +K Sbjct: 813 LEAIK 817
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 46.6 bits (109), Expect = 5e-05 Identities = 23/83 (27%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K D++SFG+L+WE+VT G P+ +S V V ++ ++C + ++ Sbjct: 664 FSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDG--YRLEKPEHCRRELYNIMY 721 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 C + P++RP F ++++ L+K+ Sbjct: 722 YCWSHDPQERPLFAEIIQMLDKL 744
>LIMK2_CHICK (P53666) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 642 Score = 46.6 bits (109), Expect = 5e-05 Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 4/92 (4%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVAT----DKLKPMDPQDYCPAAVRP 388 Y+ VD++SFG++L E++ + P + + + +K P D CP A P Sbjct: 523 YDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPAD----CPPAFFP 578 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVMSQ 292 L CC L+PE RP F +L + E + + + Sbjct: 579 LAAICCRLEPESRPPFSKLEDSFEALSLYLGE 610
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+SFG+L+WE+ T G P+ + PV+ + + + + MD C + ++ Sbjct: 670 YTHQSDVWSFGVLMWEIFTLGGSPYPGI-PVEELFKLLKEGHR-MDKPANCTNELYMMMR 727 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD 277 C P RP F QLV+ L++I ++ + LD Sbjct: 728 DCWHAIPSHRPTFKQLVEDLDRILTLTTNEEYLD 761
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 46.6 bits (109), Expect = 5e-05 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 1/90 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 +++K DV+SFG+LL+E+ T G+ P+E ++ + ++ P CPA V L+ Sbjct: 407 FSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPRPA--VCPAEVYVLMV 464 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQG 289 +C PE+RP F L + L I + G Sbjct: 465 ECWKGSPEERPTFAILREKLNAINRRLHLG 494
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 46.6 bits (109), Expect = 5e-05 Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVTGRIPFENLSPVQVAYA-VATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 D+YS G++L+++VTGR+PF+ SP+ +AYA V + P P AV L+ + Sbjct: 211 DLYSVGIMLFQLVTGRLPFDADSPLAIAYAHVQEQPVAPSAVNRALPPAVDALVARALKK 270 Query: 363 QPEKR 349 P +R Sbjct: 271 NPNER 275
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 46.2 bits (108), Expect = 6e-05 Identities = 23/78 (29%), Positives = 41/78 (52%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVDV+S G+++ EM+ G P+ N +P++ Y +AT+ + + +R + Sbjct: 1123 KEYGPKVDVWSLGIMIIEMLEGEPPYLNETPLRALYLIATNGTPKLKDPESLSYDIRKFL 1182 Query: 381 EQCCALQPEKRPDFWQLV 328 C + KR D +L+ Sbjct: 1183 AWCLQVDFNKRADADELL 1200
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+L+ E+VT GRIP+ ++ +V + P D CP + L+ QC Sbjct: 419 KSDVWSFGILMTEIVTHGRIPYPGMTNPEVIQNLERGYRMPRP--DNCPEELYKLMMQCW 476 Query: 369 ALQPEKRPDFWQLVKTLE 316 +P+ RP F L LE Sbjct: 477 RERPDDRPTFDYLRSVLE 494
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 46.2 bits (108), Expect = 6e-05 Identities = 22/79 (27%), Positives = 41/79 (51%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 K Y KVDV+S G++ EMV G P+ N +P++ Y +AT + + + + Sbjct: 555 KEYGFKVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATIGTPKISRPELLSSVFHDFL 614 Query: 381 EQCCALQPEKRPDFWQLVK 325 + + P++RP +L++ Sbjct: 615 SKSLTVNPKQRPSSGELLR 633
>KIN31_CAEEL (P34265) Probable tyrosine-protein kinase kin-31 (EC 2.7.10.2)| Length = 437 Score = 46.2 bits (108), Expect = 6e-05 Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 552 NRKVDVYSFGLLLWEMV-TGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQ 376 ++K DV+++G+L WE+ G P+ L+ +VA V TD + M P V+ L+ + Sbjct: 300 SQKTDVWAYGILCWEIFNNGAEPYPGLTANEVAKQV-TDGYR-MPPHQLAAPEVQALMTR 357 Query: 375 CCALQPEKRPDFWQLVKTLEKI 310 CCA P RP + + L+++ Sbjct: 358 CCAENPNDRPTMSDVAQILQRV 379
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 46.2 bits (108), Expect = 6e-05 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 + + DV+S+G+++WE+++ G P+ ++S V A+ D P P CP + L Sbjct: 817 RKFTSSSDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIDQDYRLPPPPD--CPTVLHLL 874 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKI 310 + C +RP F Q+V L+K+ Sbjct: 875 MLDCWQKDRVQRPKFEQIVSALDKM 899
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 46.2 bits (108), Expect = 6e-05 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ DV+SFG++LWEM T P++ LS QV V + M+ + CP + L++ Sbjct: 1573 YSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGV--MERPENCPDFLHKLMQ 1630 Query: 378 QCCALQPEKRPDFWQLVKTLE 316 +C + RP F ++ LE Sbjct: 1631 RCWHHRSSARPSFLDIIAYLE 1651
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 46.2 bits (108), Expect = 6e-05 Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K DV+SFG+LL+E++T G++P+ ++ QV +A + P CP ++ Sbjct: 410 FSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSN--CPQQFYNIML 467 Query: 378 QCCALQPEKRPDFWQLVKTLE 316 +C +P++RP F L LE Sbjct: 468 ECWNAEPKERPTFETLRWKLE 488
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 46.2 bits (108), Expect = 6e-05 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K DV++ G+L+WE+ T G +P + +V + K + P+ CP+ + L++ Sbjct: 983 FSTKSDVWASGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEG-CPSKLYRLMQ 1041 Query: 378 QCCALQPEKRPDFWQLVKTL 319 +C AL P+ RP F ++ L Sbjct: 1042 RCWALSPKDRPSFSEIASAL 1061
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 46.2 bits (108), Expect = 6e-05 Identities = 24/82 (29%), Positives = 45/82 (54%), Gaps = 1/82 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ LWE+ + G P+ + Y + + + + P+ + PA + +++ Sbjct: 844 YTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPE-HAPAEMYDVMK 902 Query: 378 QCCALQPEKRPDFWQLVKTLEK 313 C P KRP F Q+V+ +EK Sbjct: 903 TCWDADPLKRPTFKQVVQLIEK 924
>BMR1A_MOUSE (P36895) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) Length = 532 Score = 45.8 bits (107), Expect = 8e-05 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 19/96 (19%) Frame = -1 Query: 540 DVYSFGLLLWEM----VTG------RIPFENLSPVQVAY-----AVATDKLKPMDP---- 418 D+YSFGL++WEM +TG ++P+ N+ P +Y V +L+P+ Sbjct: 429 DIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWN 488 Query: 417 QDYCPAAVRPLIEQCCALQPEKRPDFWQLVKTLEKI 310 D C AV L+ +C A P R ++ KTL K+ Sbjct: 489 SDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKM 524
>BMR1A_HUMAN (P36894) Bone morphogenetic protein receptor type IA precursor (EC| 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen) Length = 532 Score = 45.8 bits (107), Expect = 8e-05 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 19/96 (19%) Frame = -1 Query: 540 DVYSFGLLLWEM----VTG------RIPFENLSPVQVAY-----AVATDKLKPMDP---- 418 D+YSFGL++WEM +TG ++P+ N+ P +Y V +L+P+ Sbjct: 429 DIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWN 488 Query: 417 QDYCPAAVRPLIEQCCALQPEKRPDFWQLVKTLEKI 310 D C AV L+ +C A P R ++ KTL K+ Sbjct: 489 SDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKM 524
>PKN1_COREF (Q8FUI5) Probable serine/threonine protein kinase CE0033 (EC| 2.7.11.1) Length = 660 Score = 45.8 bits (107), Expect = 8e-05 Identities = 23/51 (45%), Positives = 32/51 (62%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDY 409 KP + + DVY+ G +L+E+VTGR PFE SP VAY + +P P +Y Sbjct: 189 KPADARSDVYAAGCVLYELVTGRPPFEGESPFAVAYQHVQE--EPTPPSEY 237
>CSF1R_RAT (Q00495) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 978 Score = 45.8 bits (107), Expect = 8e-05 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 1/104 (0%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+LLWE+ + G P+ + Y + D + P + P + +++ Sbjct: 830 YTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPV-FAPKNIYSIMQ 888 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSSGHKKG 247 C L+P +RP F Q+ L++ + + L SSG G Sbjct: 889 SCWDLEPTRRPTFQQICFLLQEQARLERRDQDYANLPSSGGSSG 932
>EPHB6_MOUSE (O08644) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) (MEP) Length = 1014 Score = 45.8 bits (107), Expect = 8e-05 Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 5/98 (5%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y DV+SFG+L+WE+++ G P+ +++ +V A+ + P P CP + L+ Sbjct: 831 YTTSSDVWSFGILMWEVMSYGERPYWDMNEQEVLNAIEQEFRLP--PPPGCPPGLHLLML 888 Query: 378 QCCALQPEKRPDFWQLV----KTLEKIQSVMSQGGSLD 277 +RP F QLV K + K ++ ++GGS D Sbjct: 889 DTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGGSGD 926
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 45.8 bits (107), Expect = 8e-05 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 1/104 (0%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+LLWE+ + G P+ + Y + D + P + P + +++ Sbjct: 830 YTVQSDVWSYGILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPV-FAPKNIYSIMQ 888 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSSGHKKG 247 C L+P +RP F Q+ L++ + + L SSG G Sbjct: 889 SCWDLEPTRRPTFQQICFLLQEQARLERRDQDYANLPSSGGSSG 932
>PKAA_STRCO (P54739) Serine/threonine protein kinase pkaA (EC 2.7.11.1)| Length = 543 Score = 45.4 bits (106), Expect = 1e-04 Identities = 28/84 (33%), Positives = 43/84 (51%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLI 382 +P VDVY G+LL+E+VTGR PF S ++V + + +P P P + +I Sbjct: 196 RPQTSAVDVYGAGILLYELVTGRPPFGGGSALEVLHQHLS--AEPRRPST-VPDPLWTVI 252 Query: 381 EQCCALQPEKRPDFWQLVKTLEKI 310 E+C P+ RP L + L + Sbjct: 253 ERCLRKNPDDRPSAENLARGLRVV 276
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 45.4 bits (106), Expect = 1e-04 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GRIP+ ++ +V + ++ M D CP + L+ C Sbjct: 419 KSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL--ERGYRMVRPDNCPEELYQLMRLCW 476 Query: 369 ALQPEKRPDFWQLVKTLE 316 +PE RP F L LE Sbjct: 477 KERPEDRPTFDYLRSVLE 494
>EPHA1_MOUSE (Q60750) Ephrin type-A receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ESK) Length = 977 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG+++WE+++ G P+ +S +V ++ P P CPA + L++ C A Sbjct: 809 DVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLP--PPVDCPAPLYELMKNCWAY 866 Query: 363 QPEKRPDFWQLVKTLEKI 310 +RP F QL LE++ Sbjct: 867 DRARRPHFLQLQAHLEQL 884
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y+ K DV+SFG+LL EM + G++P+ +S + V P + CP +V L+ Sbjct: 364 YSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLE--CPPSVHKLML 421 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQS 304 C PE+RP F L + L S Sbjct: 422 TCWCRDPEQRPCFKALRERLSSFTS 446
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 45.4 bits (106), Expect = 1e-04 Identities = 22/72 (30%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDP-QDYCPAAVRPL 385 K +R+VDVY+ G++L+E++TG+ PF+ + V V A+ + P+ + P A++ + Sbjct: 194 KAMDRRVDVYALGVVLYELLTGKRPFDATTDVSVMQAILFESFIPVSARRPDVPVALQQV 253 Query: 384 IEQCCALQPEKR 349 +++ A E+R Sbjct: 254 LDKALAKDRERR 265
>XMRK_XIPMA (P13388) Melanoma receptor tyrosine-protein kinase precursor (EC| 2.7.10.1) Length = 1167 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y + DV+S+G+ +WE++T G P++ + ++A + + P P C V +I Sbjct: 889 YTHQSDVWSYGVTVWELMTFGSKPYDGIPAKEIASVLENGERLPQPP--ICTIEVYMIIL 946 Query: 378 QCCALQPEKRPDFWQLV 328 +C + P RP F +LV Sbjct: 947 KCWMIDPSSRPRFRELV 963
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ P P D CP A+ L+ C Sbjct: 806 DVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP-PPMD-CPIALHQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKI 310 + RP F Q+V L+K+ Sbjct: 864 ERSDRPKFGQIVNMLDKL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ P P D CP A+ L+ C Sbjct: 806 DVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP-PPMD-CPIALHQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKI 310 + RP F Q+V L+K+ Sbjct: 864 ERSDRPKFGQIVNMLDKL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ P P D CP A+ L+ C Sbjct: 806 DVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP-PPMD-CPIALHQLMLDCWQK 863 Query: 363 QPEKRPDFWQLVKTLEKI 310 + RP F Q+V L+K+ Sbjct: 864 ERSDRPKFGQIVNMLDKL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 45.4 bits (106), Expect = 1e-04 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ P P D CP A+ L+ C Sbjct: 805 DVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP-PPMD-CPIALHQLMLDCWQK 862 Query: 363 QPEKRPDFWQLVKTLEKI 310 + RP F Q+V L+K+ Sbjct: 863 ERSDRPKFGQIVSMLDKL 880
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/78 (34%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+V+ G P+ ++ V AV P P D CPAA+ L+ C Sbjct: 860 DVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLP-SPMD-CPAALYQLMLDCWQK 917 Query: 363 QPEKRPDFWQLVKTLEKI 310 + RP F ++V L+K+ Sbjct: 918 ERNSRPKFDEIVNMLDKL 935
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 + K DV+SFG+LLWE++T G P+ +++ + + + L+P +YCP + + Sbjct: 1260 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP----EYCPDPLYEV 1315 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 + +C + E RP F +LV + I S Sbjct: 1316 MLKCWHPKAEMRPSFSELVSRISAIFS 1342
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 + K DV+SFG+LLWE++T G P+ +++ + + + L+P +YCP + + Sbjct: 1260 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP----EYCPDPLYEV 1315 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 + +C + E RP F +LV + I S Sbjct: 1316 MLKCWHPKAEMRPSFSELVSRISAIFS 1342
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 + K DV+SFG+LLWE++T G P+ +++ + + + L+P +YCP + + Sbjct: 1260 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP----EYCPDPLYEV 1315 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 + +C + E RP F +LV + I S Sbjct: 1316 MLKCWHPKAEMRPSFSELVSRISAIFS 1342
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 + K DV+SFG+LLWE++T G P+ +++ + + + L+P +YCP + + Sbjct: 1260 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP----EYCPDPLYEV 1315 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 + +C + E RP F +LV + I S Sbjct: 1316 MLKCWHPKAEMRPSFSELVSRISAIFS 1342
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 + K DV+SFG+LLWE++T G P+ +++ + + + L+P +YCP + + Sbjct: 1261 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP----EYCPDPLYEV 1316 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 + +C + E RP F +LV + I S Sbjct: 1317 MLKCWHPKAEMRPSFSELVSRISAIFS 1343
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 45.4 bits (106), Expect = 1e-04 Identities = 27/87 (31%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDK--LKPMDPQDYCPAAVRPL 385 + K DV+SFG+LLWE++T G P+ +++ + + + L+P +YCP + + Sbjct: 1261 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQP----EYCPDPLYEV 1316 Query: 384 IEQCCALQPEKRPDFWQLVKTLEKIQS 304 + +C + E RP F +LV + I S Sbjct: 1317 MLKCWHPKAEMRPSFSELVSRISAIFS 1343
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ + +V V P PQ CP ++ L++ C Sbjct: 449 KSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPC-PQG-CPESLHELMKLCW 506 Query: 369 ALQPEKRPDFWQLVKTLE 316 P++RP F + LE Sbjct: 507 KKDPDERPTFEYIQSFLE 524
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 45.4 bits (106), Expect = 1e-04 Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCC 370 K DV+SFG+LL E+VT GR+P+ + +V V P PQ CP ++ L++ C Sbjct: 442 KSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPC-PQG-CPESLHELMKLCW 499 Query: 369 ALQPEKRPDFWQLVKTLE 316 P++RP F + LE Sbjct: 500 KKDPDERPTFEYIQSFLE 517
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 45.4 bits (106), Expect = 1e-04 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Frame = -1 Query: 546 KVDVYSFGLLLWEMVTGRIPFEN-LSPVQVAYAVATDKLKPMDP-QDYCPAAVRPLIEQC 373 K DVYSF ++LW + + P+EN + Q+ + + +D +YCP + L++ C Sbjct: 208 KSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLC 267 Query: 372 CALQPEKRPDF 340 PE RP F Sbjct: 268 WEANPEARPTF 278
>PGFRA_MOUSE (P26618) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1089 Score = 45.1 bits (105), Expect = 1e-04 Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y DV+S+G+LLWE+ + G P+ + Y + P D+ + V ++ Sbjct: 872 YTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKP-DHATSEVYEIMV 930 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 QC +PEKRP F+ L + +E + Sbjct: 931 QCWNSEPEKRPSFYHLSEIVENL 953
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+ + P++ LS QV V +D + CP + L++ C Sbjct: 1207 DVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGG--SLDHPENCPPRLHSLMQMCWQY 1264 Query: 363 QPEKRPDFWQLVKTLE 316 P+ RP F +++ L+ Sbjct: 1265 NPKMRPTFLEIIDMLK 1280
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 45.1 bits (105), Expect = 1e-04 Identities = 34/93 (36%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Frame = -1 Query: 555 YNR---KVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRP 388 YNR K DV+SFG+L+ E+VT GRIP+ ++ Q V P+ P CP + Sbjct: 410 YNRFTIKSDVWSFGILMAEIVTKGRIPYPGMTNAQTIAEVEKGYRMPIMPG--CPEPLYN 467 Query: 387 LIEQCCALQPEKRPDFWQLVKTLEKIQSVMSQG 289 ++ Q PE RP F L LE QG Sbjct: 468 IMLQTWNKDPENRPTFDYLQGVLEDYFVSTEQG 500
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/92 (30%), Positives = 50/92 (54%), Gaps = 5/92 (5%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ ++S V A+ P P D CP ++ L+ C Sbjct: 189 DVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP-PPMD-CPVSLHQLMLDCWQK 246 Query: 363 QPEKRPDFWQLVKTLEKI----QSVMSQGGSL 280 + +RP F Q+V L+K+ S+ GG + Sbjct: 247 ERAERPKFSQIVNMLDKLIRNPNSLKRTGGEI 278
>ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.10.2) (ACK-2)| Length = 747 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 1/75 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 + ++ D + FG+ LWEM T G+ P+ L+ Q+ + + + + P+D CP + + Sbjct: 305 RTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPED-CPQDIYNV 363 Query: 384 IEQCCALQPEKRPDF 340 + QC A +PE RP F Sbjct: 364 MVQCWAHKPEDRPTF 378
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+S+G+++WE+++ G P+ +S V AV P P D CP + L+ C Sbjct: 811 DVWSYGIVMWEVISYGERPYWEMSNQDVIKAVDEGYRLPA-PMD-CPVVLHQLMLDCWEK 868 Query: 363 QPEKRPDFWQLVKTLEKI 310 RP F Q+V TL+++ Sbjct: 869 NRSDRPKFGQIVNTLDRL 886
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Frame = -1 Query: 540 DVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIEQCCAL 364 DV+SFG++LWE+VT P++ LS QV V + ++ + CP ++ L+ +C Sbjct: 1174 DVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGV--LEELEGCPLQLQELMSRCWQP 1231 Query: 363 QPEKRPDFWQLVKTLEK 313 P RP F ++ ++++ Sbjct: 1232 NPRLRPSFTHILDSIQE 1248
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 +++K DV+SFG+LL E+ T G+ P+E ++ + + P CPA V L+ Sbjct: 403 FSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAA--CPAEVYVLML 460 Query: 378 QCCALQPEKRPDFWQLVKTLEKI 310 +C PE+RP F L + L I Sbjct: 461 ECWRSSPEERPSFATLREKLHAI 483
>TYRO3_HUMAN (Q06418) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase DTK) (Protein-tyrosine kinase byk) Length = 890 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVA-YAVATDKLKPMDPQDYCPAAVRPLI 382 Y + DV++FG+ +WE++T G+ P+ + ++ Y + ++LK P + C V L+ Sbjct: 709 YTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLK--QPPE-CMEDVYDLM 765 Query: 381 EQCCALQPEKRPDFWQLVKTLEKIQSVMS 295 QC + P++RP F L LE I +S Sbjct: 766 YQCWSADPKQRPSFTCLRMELENILGQLS 794
>EPHB6_RAT (P0C0K7) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) Length = 1013 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 5/98 (5%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 Y DV+SFG+L+WE+++ G P+ ++S +V A+ + P P CP + L+ Sbjct: 830 YTTSSDVWSFGILMWEVMSYGERPYWDMSDQEVLNAIEQEFRLP--PPPGCPTGLHLLML 887 Query: 378 QCCALQPEKRPDFWQLV----KTLEKIQSVMSQGGSLD 277 +RP F QLV K + K ++ ++G S D Sbjct: 888 DTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGSSGD 925
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 45.1 bits (105), Expect = 1e-04 Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 2/82 (2%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQV-AYAVATDKLKPMDPQDYCPAAVRPLI 382 Y K DV+SFG+ +WE+ T G+ P+ + ++ Y ++LK P D C + L+ Sbjct: 719 YTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLK--QPAD-CLDGLYALM 775 Query: 381 EQCCALQPEKRPDFWQLVKTLE 316 +C L P+ RP F +L + LE Sbjct: 776 SRCWELNPQDRPSFTELREDLE 797
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 1/112 (0%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K DV++FG+LLWE+ T G P+ + QV + D M+ + CP V L+ Sbjct: 416 FSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKD--YRMERPEGCPEKVYELMR 473 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLDTLRSSGHKKGLKHWIQKL 223 C P RP F ++ + E ++ + D + K+G++ + L Sbjct: 474 ACWQWNPSDRPSFAEIHQAFE---TMFQESSISDEVEKELGKQGVRGAVSTL 522
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 45.1 bits (105), Expect = 1e-04 Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Frame = -1 Query: 555 YNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 ++ K DV++FG+LLWE+ T G P+ + V Y + + + MD CP +V L+ Sbjct: 485 FSSKSDVWAFGVLLWEIATYGMAPYPGVELSNV-YGLLENGFR-MDGPQGCPPSVYRLML 542 Query: 378 QCCALQPEKRPDFWQLVKTLEKIQSVMSQGGSLD-TLRSSGHKK 250 QC P RP F + LE + S S + L+ + KK Sbjct: 543 QCWNWSPSDRPRFRDIHFNLENLISSNSLNDEVQKQLKKNNDKK 586
>NEK1_CAEEL (P84199) Serine/threonine-protein kinase D1044.8 (EC 2.7.11.1)| Length = 959 Score = 45.1 bits (105), Expect = 1e-04 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 5/111 (4%) Frame = -1 Query: 558 PYNRKVDVYSFGLLLWEMVTGRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPLIE 379 PY K D++SFG ++EM + F + + + +A + K P++ + +R LI Sbjct: 618 PYGEKADIWSFGCCIYEMCQLQPVFHSTNMLTLAMQIVEAKYDPLN--EMWSDDLRFLIT 675 Query: 378 QCCALQPEKRPDFWQL-----VKTLEKIQSVMSQGGSLDTLRSSGHKKGLK 241 C A P RPD ++ V+ LE + V Q S + +S +K Sbjct: 676 SCLAPDPSARPDILKVSGMCGVRLLEYLDDVARQQASTSDMTASQSSYNIK 726
>ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1)| (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2) Length = 1055 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 1/75 (1%) Frame = -1 Query: 561 KPYNRKVDVYSFGLLLWEMVT-GRIPFENLSPVQVAYAVATDKLKPMDPQDYCPAAVRPL 385 + ++ D + FG+ LWEM T G+ P+ L+ Q+ + + + + P+D CP + + Sbjct: 305 RTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPED-CPQDIYNV 363 Query: 384 IEQCCALQPEKRPDF 340 + QC A +PE RP F Sbjct: 364 MVQCWAHKPEDRPTF 378 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 81,038,188 Number of Sequences: 219361 Number of extensions: 1653025 Number of successful extensions: 5624 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5062 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5243 length of database: 80,573,946 effective HSP length: 106 effective length of database: 57,321,680 effective search space used: 4585734400 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
