>CYTL_TACTR (Q7M429) L-cystatin precursor|
          Length = 133

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 22/56 (39%), Positives = 34/56 (60%)
 Frame = -3

Query: 445 LGAKRGGHEPGWRDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVV 278
           +G   G    GW D  V D  VK+AA  A ++   RSNSL+ ++L++I +A+ +VV
Sbjct: 14  VGVSMGQIPGGWIDANVGDTDVKEAARFATEAQSSRSNSLYHHKLLKIHKARTQVV 69

>CYTC_BOVIN (P01035) Cystatin C precursor (Colostrum thiol proteinase|
           inhibitor)
          Length = 148

 Score = 35.4 bits (80), Expect = 0.085
 Identities = 18/61 (29%), Positives = 32/61 (52%)
 Frame = -3

Query: 442 GAKRGGHEPGWRDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVVEDFAK 263
           G ++G    G  +  V++  V++A S AV    +RSN  +   ++ +VRA+ +VV     
Sbjct: 32  GPRKGRLLGGLMEADVNEEGVQEALSFAVSEFNKRSNDAYQSRVVRVVRARKQVVSGMNY 91

Query: 262 F 260
           F
Sbjct: 92  F 92

>KNT1_RAT (P01048) T-kininogen 1 precursor (T-kininogen I) (Major acute phase|
           protein) (Alpha-1-MAP) (Thiostatin) [Contains:
           T-kininogen 1 heavy chain (T-kininogen I heavy chain);
           T-kinin; T-kininogen 1 light chain (T-kininogen I light
           chain)]
          Length = 430

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 12/44 (27%), Positives = 28/44 (63%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVV 278
           R++PV  P +K+A  H++  +  + N +F +++  + +A ++VV
Sbjct: 268 REIPVDSPELKEALGHSIAQLNAQHNHIFYFKIDTVKKATSQVV 311

>KNT2_RAT (P08932) T-kininogen 2 precursor (T-kininogen II) (Major acute|
           phase protein) (Alpha-1-MAP) (Thiostatin) [Contains:
           T-kininogen 2 heavy chain (T-kininogen II heavy chain);
           T-kinin; T-kininogen 2 light chain (T-kininogen I light
           chain)]
          Length = 430

 Score = 33.5 bits (75), Expect = 0.32
 Identities = 12/44 (27%), Positives = 28/44 (63%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVV 278
           +++PV  P +K+A  H++  +  + N LF +++  + +A ++VV
Sbjct: 268 KNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVV 311

>KNG1_RAT (P08934) Kininogen-1 precursor [Contains: Kininogen-1 heavy chain;|
           Bradykinin; Kininogen-1 light chain]
          Length = 639

 Score = 33.1 bits (74), Expect = 0.42
 Identities = 12/44 (27%), Positives = 27/44 (61%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVV 278
           R++PV  P +K+A  H++  +   +N  F +++  + +A ++VV
Sbjct: 269 RNIPVDSPELKEALGHSIAQLNAENNHTFYFKIDTVKKATSQVV 312

>KNG1_MOUSE (O08677) Kininogen-1 precursor [Contains: Kininogen-1 heavy chain;|
           Bradykinin; Kininogen-1 light chain]
          Length = 661

 Score = 32.3 bits (72), Expect = 0.72
 Identities = 12/44 (27%), Positives = 26/44 (59%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVV 278
           RD+PV  P +K+   H++  +   ++  F Y++  + +A ++VV
Sbjct: 268 RDIPVDSPELKEVLGHSIAQLNAENDHPFYYKIDTVKKATSQVV 311

>CYTM_HUMAN (Q15828) Cystatin M precursor (Cystatin E)|
          Length = 149

 Score = 32.3 bits (72), Expect = 0.72
 Identities = 17/50 (34%), Positives = 28/50 (56%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVVEDFAKF 260
           RD+   DP V+ AA  AV S    SNS++ +    I++A++++V     F
Sbjct: 39  RDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYF 88

>NFM_HUMAN (P07197) Neurofilament triplet M protein (160 kDa neurofilament|
           protein) (Neurofilament medium polypeptide) (NF-M)
           (Neurofilament 3)
          Length = 915

 Score = 32.0 bits (71), Expect = 0.94
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
 Frame = -3

Query: 421 EPGWRDVPVHDPVVKDAASHAVKS-IQERSNSLFPYELIEIVRAKAEVVEDFAKFDIVMK 245
           E G   VP   PV +   S   KS ++E++ S  P   +E  ++KAEV +   K +   +
Sbjct: 649 EKGKSPVP-KSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 707

Query: 244 LKRGTKEEKMKAEVHK 197
           +K   KEEK++ +  K
Sbjct: 708 VKEAPKEEKVEKKEEK 723

>KNG2_BOVIN (P01045) Kininogen-2 precursor (Kininogen II) (Thiol proteinase|
           inhibitor) [Contains: Kininogen-2 heavy chain;
           Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II);
           Kininogen-2 light chain]
          Length = 619

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 16/74 (21%), Positives = 37/74 (50%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVVEDFAKFDIVMKLKRGT 230
           + +PV  P +++A +H++  +    +  F +++  + +A  +VV    K+ IV   +  T
Sbjct: 266 KPIPVDSPDLEEALNHSIAKLNAEHDGTFYFKIDTVKKATVQVVGGL-KYSIVFIARETT 324

Query: 229 KEEKMKAEVHKNLE 188
             +    E+ K+ E
Sbjct: 325 CSKGSNEELTKSCE 338

>SC5A6_RAT (O70247) Sodium-dependent multivitamin transporter (Na(+)-dependent|
           multivitamin transporter)
          Length = 634

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
 Frame = +3

Query: 222 SSFVPLFSFMTISNLAKSSTTSAFARTISISSYGKREFDLSWIDFTAW---------LAA 374
           SSF+P       SNL  ++ T+    T+S  +  ++ + LS++ ++A          L  
Sbjct: 491 SSFLP-------SNLTVATVTTLMPSTLSKPTGLQQFYSLSYLWYSAHNSTTVIAVGLIV 543

Query: 375 SLTTGSCTGTSRHPGSCPPLL 437
           SL TG   G S +PG+  P+L
Sbjct: 544 SLLTGGMRGRSLNPGTIYPVL 564

>KNG1_BOVIN (P01044) Kininogen-1 precursor (Kininogen I) (Thiol proteinase|
           inhibitor) [Contains: Kininogen-1 heavy chain;
           Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II);
           Kininogen-1 light chain]
          Length = 621

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 16/74 (21%), Positives = 36/74 (48%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVVEDFAKFDIVMKLKRGT 230
           + +PV  P +++  SH++  +    +  F +++  + +A  +VV    K+ IV   +  T
Sbjct: 268 KPIPVDSPDLEEPLSHSIAKLNAEHDGAFYFKIDTVKKATVQVVAGL-KYSIVFIARETT 326

Query: 229 KEEKMKAEVHKNLE 188
             +    E+ K+ E
Sbjct: 327 CSKGSNEELTKSCE 340

>RPSK_BACSU (P12254) RNA polymerase sigma-K factor precursor (Sigma-27)|
          Length = 294

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
 Frame = -3

Query: 409 RDVPVHDPVVKDAASHAVKSI----QERSNSLFPYEL---IEIVRAKAEVVEDFAKFDIV 251
           +DV +HDP+ +D   + +  I     E  + +   +L   +E V+   ++++D  K  IV
Sbjct: 179 KDVSLHDPIGQDKEGNEISLIDVLKSENEDVIDTIQLNMELEKVKQYIDILDDREKEVIV 238

Query: 250 MKLKRGTKEEKMKAEVHKNL 191
            +     K+EK + E+ K L
Sbjct: 239 GRFGLDLKKEKTQREIAKEL 258

>GLTB1_ARATH (Q9ZNZ7) Ferredoxin-dependent glutamate synthase 1, chloroplast|
           precursor (EC 1.4.7.1) (Fd-GOGAT 1)
          Length = 1648

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 14/38 (36%), Positives = 22/38 (57%)
 Frame = -3

Query: 454 ISDLGAKRGGHEPGWRDVPVHDPVVKDAASHAVKSIQE 341
           I ++  K G    GWR+VPV+ P+V   A   + +IQ+
Sbjct: 224 IENIFEKEGLQVLGWREVPVNVPIVGKNARETMPNIQQ 261

>RL3_MYCPE (Q8EUB3) 50S ribosomal protein L3|
          Length = 310

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 22/90 (24%), Positives = 44/90 (48%)
 Frame = -3

Query: 403 VPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVVEDFAKFDIVMKLKRGTKE 224
           + + DP   +A + A+K  +E++      +  E    KAE  ++  K +++ K K    E
Sbjct: 217 IKLSDP---EAIARAIKEKEEQARLALEAKKAE-AHQKAEAEKEAKKQEMLAKQKAA--E 270

Query: 223 EKMKAEVHKNLEGAFVLNQMQPEHDESSSQ 134
           EK KAE  KN +      +   + D+++++
Sbjct: 271 EKQKAEAEKNEQPTATAEEAPAKTDDNATE 300

>OS9_HUMAN (Q13438) Protein OS-9 precursor (Amplified in osteosarcoma 9)|
          Length = 667

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 20/95 (21%), Positives = 42/95 (44%)
 Frame = -3

Query: 418 PGWRDVPVHDPVVKDAASHAVKSIQERSNSLFPYELIEIVRAKAEVVEDFAKFDIVMKLK 239
           PG  +VP  +   +D +  A  S     N       ++++R+ A+++        + +LK
Sbjct: 323 PGGEEVPAEE---QDPSPEAADSASGAPNDFQNNVQVKVIRSPADLIR------FIEELK 373

Query: 238 RGTKEEKMKAEVHKNLEGAFVLNQMQPEHDESSSQ 134
            GTK+ K      + ++ A  + Q +PE +    +
Sbjct: 374 GGTKKGKPNIGQEQPVDDAAEVPQREPEKERGDPE 408

>FIT1_YEAST (Q04433) Facilitator of iron transport 1 precursor|
          Length = 528

 Score = 29.6 bits (65), Expect = 4.7
 Identities = 19/48 (39%), Positives = 25/48 (52%)
 Frame = +3

Query: 174 STKAPSRFLCTSAFIFSSFVPLFSFMTISNLAKSSTTSAFARTISISS 317
           S +A S    +SA   SS VP FS  T  N + S +TSA   + + SS
Sbjct: 383 SVQASSPIETSSAAKTSSVVPTFSSTTTENSSNSKSTSAVVASTTTSS 430

>HMDH1_ORYSA (P48019) 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (EC|
           1.1.1.34) (HMG-CoA reductase 1)
          Length = 509

 Score = 29.3 bits (64), Expect = 6.1
 Identities = 15/41 (36%), Positives = 24/41 (58%)
 Frame = -3

Query: 298 RAKAEVVEDFAKFDIVMKLKRGTKEEKMKAEVHKNLEGAFV 176
           R K+ V E   K D+V K+ + T E+ ++  + KNL G+ V
Sbjct: 331 RGKSVVCEAIIKGDVVQKVLKTTVEKLVELNIIKNLAGSAV 371

>LYST_MOUSE (P97412) Lysosomal trafficking regulator (Beige protein) (CHS1|
            homolog)
          Length = 3788

 Score = 29.3 bits (64), Expect = 6.1
 Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
 Frame = +2

Query: 134  LAARFVMLRLHLVQHKSSLKVLM--HLGFHFLLLCPSLQFH 250
            LAA  V++R+   Q + ++K L+  H+  HFLL C  LQ H
Sbjct: 1930 LAALEVLIRVEHHQQQFNIKQLLNAHVVHHFLLTCQVLQEH 1970

>SYEC_YEAST (P46655) Glutamyl-tRNA synthetase, cytoplasmic (EC 6.1.1.17)|
           (Glutamate--tRNA ligase) (GluRS) (P85)
          Length = 724

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 20/81 (24%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
 Frame = -3

Query: 412 WRDVPVHD---PVVK--DAASHAVKSIQERSNSLFPYELIEIVRAKAEVVEDFAKFDIVM 248
           W+  P +D   P+V   +  +HA+++I+ R  +     +++ +R +   + DFA+ + V 
Sbjct: 392 WKIYPTYDFCVPIVDAIEGVTHALRTIEYRDRNAQYDWMLQALRLRKVHIWDFARINFVR 451

Query: 247 KLKRGTKEEKMKAEVHKNLEG 185
            L     + K++  V K+L G
Sbjct: 452 TL---LSKRKLQWMVDKDLVG 469

>ATG2_MAGGR (Q51ZN8) Autophagy-related protein 2|
          Length = 2077

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 22/59 (37%), Positives = 27/59 (45%)
 Frame = +3

Query: 321 GKREFDLSWIDFTAWLAASLTTGSCTGTSRHPGSCPPLLAPRSEMVKEVASPVWRNSCS 497
           GKR   L   D TA+L +     S   T     S PP L+P+S     + SPV R S S
Sbjct: 261 GKRLVSLQ--DITAFLISEANVFS---TFERTTSVPPSLSPQSSAASALRSPVSRESTS 314


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,697,047
Number of Sequences: 219361
Number of extensions: 1151288
Number of successful extensions: 3474
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 3380
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3474
length of database: 80,573,946
effective HSP length: 104
effective length of database: 57,760,402
effective search space used: 3523384522
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)