ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal13b22 |
|---|---|
| Clone Library Name | barley_pub |
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 121 bits (303), Expect = 2e-27 Identities = 58/130 (44%), Positives = 84/130 (64%), Gaps = 7/130 (5%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GTYGYMSPEYA GI+S KSDVFSFGV++LEI+SGK+N F+ + +LL Y W W+ Sbjct: 692 GTYGYMSPEYAMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKE 751 Query: 489 GRCLELLEASVANEVHA-------AEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSV 331 GR LE+++ + + + + E + + L+CVQE A+ RP MS+V+ M S++ Sbjct: 752 GRALEIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMFGSEAT 811 Query: 330 VLPKPNHPAY 301 +P+P P Y Sbjct: 812 EIPQPKPPGY 821
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 70.5 bits (171), Expect = 4e-12 Identities = 39/110 (35%), Positives = 63/110 (57%), Gaps = 1/110 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GTYGY +PEYA G +VKSDV+SFGV+ LE+I+G++ NL+ ++ L+ Sbjct: 252 GTYGYCAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFND 311 Query: 489 GR-CLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 R ++L + + + + A MC+QE A RP +++V+T L+ Sbjct: 312 RRKFIKLADPRLKGRFPTRALYQALAVASMCIQEQAATRPLIADVVTALS 361
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 70.1 bits (170), Expect = 6e-12 Identities = 40/123 (32%), Positives = 70/123 (56%), Gaps = 1/123 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GTYGY +P+YA G + KSD++SFGV+LLE+I+G++ + NL+G++ L++ Sbjct: 269 GTYGYCAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKD 328 Query: 489 GRCL-ELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLPKPN 313 R ++++ + + + + + MCVQE RP +S+V+ LN + PN Sbjct: 329 RRNFPKMVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPN 388 Query: 312 HPA 304 P+ Sbjct: 389 SPS 391
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 70.1 bits (170), Expect = 6e-12 Identities = 40/108 (37%), Positives = 61/108 (56%), Gaps = 1/108 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY + K DV+S+GV+LLE++SGK+ E + NL+G++ QL+ Sbjct: 1024 GTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYRE 1083 Query: 489 GRCLELLEAS-VANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITM 349 R E+L+ V ++ E Y+ A C+ + RPTM V+TM Sbjct: 1084 KRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTM 1131
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 70.1 bits (170), Expect = 6e-12 Identities = 39/115 (33%), Positives = 63/115 (54%), Gaps = 2/115 (1%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHE--HEDFLNLLGYSWQLW 496 GT G+++PEY S G S K+DVF +GV+LLE+I+G+R ++D + LL + L Sbjct: 454 GTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLDWVKGLL 513 Query: 495 EGGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSV 331 + + L++ + E + + AL+C Q +RP MS V+ ML D + Sbjct: 514 KEKKLEALVDVDLQGNYKDEEVEQLIQVALLCTQSSPMERPKMSEVVRMLEGDGL 568
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 67.4 bits (163), Expect = 4e-11 Identities = 44/143 (30%), Positives = 71/143 (49%), Gaps = 1/143 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSW-QLWE 493 GT GY +PEY + G SVKSDV+SFGV+LLE++SG+R ++ NL+ ++ L Sbjct: 242 GTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTN 301 Query: 492 GGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLPKPN 313 R L +++ + + A + AL C+ A RPTM+ ++ K Sbjct: 302 KRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIV-----------KTM 350 Query: 312 HPAYFNLMASKEDESAPCSYNGV 244 + ASKE ++ S + + Sbjct: 351 EELHIQKEASKEQQNPQISIDNI 373
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 66.2 bits (160), Expect = 8e-11 Identities = 36/114 (31%), Positives = 59/114 (51%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY S KSDVFSFGV+LLEI+SG+ + +L+ ++ Sbjct: 760 GTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRA 819 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVV 328 + E+++ + HA R V AL C++ ++ RP M +++ L ++ Sbjct: 820 SKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELEDALII 873
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does not| make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 66.2 bits (160), Expect = 8e-11 Identities = 36/114 (31%), Positives = 59/114 (51%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY S KSDVFSFGV+LLEI+SG+ + +L+ ++ Sbjct: 761 GTAGYLDPEYYKTQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRA 820 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVV 328 + E+++ + HA R V AL C++ ++ RP M +++ L ++ Sbjct: 821 SKVDEIVDPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELEDALII 874
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 65.9 bits (159), Expect = 1e-10 Identities = 36/110 (32%), Positives = 61/110 (55%), Gaps = 2/110 (1%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR--NSSFHEHEDFLNLLGYSWQLW 496 GT+GY+ PEY + K DV+SFGV+LLE+++GK F E E NL+G++ Q Sbjct: 1081 GTFGYIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGG-NLVGWAIQKI 1139 Query: 495 EGGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 G+ +++++ + + R + A++C+ E RP M +V+ L Sbjct: 1140 NQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKAL 1189
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 65.9 bits (159), Expect = 1e-10 Identities = 38/108 (35%), Positives = 60/108 (55%), Gaps = 1/108 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY + K DV+S+GV+LLE++SGK+ E + NL+G++ QL+ Sbjct: 1026 GTPGYVPPEYYQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYRE 1085 Query: 489 GRCLELLEAS-VANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITM 349 R E+L+ V ++ E Y+ A C+ + RPTM ++ M Sbjct: 1086 KRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAM 1133
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/123 (34%), Positives = 60/123 (48%), Gaps = 15/123 (12%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY + K DV+S GV++LEI+SGKR + E D NL+G+S Sbjct: 1005 GTPGYVPPEYYQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGD-TNLVGWSKMKARE 1063 Query: 489 GRCLELLEASVANE---------------VHAAEARRYVNTALMCVQEHADDRPTMSNVI 355 G+ +E+++ + E V E RY+ AL CV + RP M V+ Sbjct: 1064 GKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVV 1123 Query: 354 TML 346 L Sbjct: 1124 ASL 1126
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/113 (30%), Positives = 60/113 (53%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY + + K DV+SFGV+LLE+++G+R + +L+ + Q+ Sbjct: 907 GTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTE 966 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSV 331 R E+ + + ++ HA E + A C+ E+ RPT +++ L + V Sbjct: 967 KRESEIFDPFIYDKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWLENIDV 1019
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/108 (33%), Positives = 57/108 (52%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY + KSDV+SFGV+LLEI+SG++ E N++ ++ L + Sbjct: 673 GTLGYLDPEYYRLHYLTTKSDVYSFGVVLLEILSGRKAIDMQFEEG--NIVEWAVPLIKA 730 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 G +L+ ++ ++ + A CV+ DRP+M V T L Sbjct: 731 GDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTAL 778
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/120 (33%), Positives = 70/120 (58%), Gaps = 7/120 (5%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR--NSSFHEHEDFLNLLGYSWQLW 496 GT GYM+PE A + S +SDV+S+GV+LLE+I+ K+ + SF+ D ++G+ +W Sbjct: 981 GTIGYMAPENAFTTVKSRESDVYSYGVVLLELITRKKALDPSFNGETD---IVGWVRSVW 1037 Query: 495 -EGGRCLELLEASVANEVHAAEARRYV----NTALMCVQEHADDRPTMSNVITMLNSDSV 331 + G ++++ S+ +E+ + V + AL C ++ D RPTM +V+ L S+ Sbjct: 1038 TQTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQLTRWSI 1097
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 63.9 bits (154), Expect = 4e-10 Identities = 31/109 (28%), Positives = 60/109 (55%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY + + K DV+SFGV+LLE+++ KR + + +L+ + ++ Sbjct: 898 GTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHE 957 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 R E+ + + ++ + E R + A +C+ E+ RPT +++ L+ Sbjct: 958 SRASEVFDPLIYSKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWLD 1006
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 62.0 bits (149), Expect = 2e-09 Identities = 36/109 (33%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GTYGY +PEY + G + KSDV+S+GV+LLE++SG+R + L+ ++ L Sbjct: 243 GTYGYAAPEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLAN 302 Query: 489 GRCL-ELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 R L +++ + ++ EA + AL C+ RP M+ V++ L Sbjct: 303 KRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHL 351
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 61.6 bits (148), Expect = 2e-09 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 1/109 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSW-QLWE 493 GT+GY +PEY + G + KSDV+SFGV+LLE++SG+R + NL+ ++ L Sbjct: 242 GTHGYAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVN 301 Query: 492 GGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 + +++ + ++ EA + +L C+ RP MS V++ L Sbjct: 302 KRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHL 350
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 60.8 bits (146), Expect = 4e-09 Identities = 45/122 (36%), Positives = 60/122 (49%), Gaps = 12/122 (9%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRN-SSFHEHEDFLNLLGYSWQLWE 493 G+YGY++PEYA KSDV+SFGV+LLE+I+GK+ F E D + W Sbjct: 856 GSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIAGKKPVGEFGEGVDIVR--------WV 907 Query: 492 GGRCLELLEASVANEVHAAEARRYV-----------NTALMCVQEHADDRPTMSNVITML 346 E+ + S A V A R A+MCV+E A RPTM V+ ML Sbjct: 908 RNTEEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHML 967 Query: 345 NS 340 + Sbjct: 968 TN 969
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 60.5 bits (145), Expect = 5e-09 Identities = 43/145 (29%), Positives = 67/145 (46%), Gaps = 6/145 (4%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG------KRNSSFHEHEDFLNLLGYS 508 GTYGY +PEY + G VKSDVF+FGV+LLEI++G KR D+L Sbjct: 257 GTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRP---- 312 Query: 507 WQLWEGGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVV 328 +L R ++++ + + A L C++ +RP M V+ +L + Sbjct: 313 -ELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQGL 371 Query: 327 LPKPNHPAYFNLMASKEDESAPCSY 253 PN + +A+ S+P Y Sbjct: 372 NVVPNRSSTKQAVAN-SSRSSPHHY 395
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/122 (28%), Positives = 68/122 (55%), Gaps = 3/122 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLW-- 496 GT+GY++PEYA G + K DV+SFGV+L+E+I+G+++ + E+ ++L+ + +++ Sbjct: 755 GTFGYLAPEYAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYIN 814 Query: 495 EGGRCLELLEASV-ANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLPK 319 + + ++ ++ +E A A C RP M + + +L+S V L K Sbjct: 815 KEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSS-LVELWK 873 Query: 318 PN 313 P+ Sbjct: 874 PS 875
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 9/120 (7%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHED--------FLNLLG 514 GT GY++PE+ S + K DV+S+GV+LLE+++G R S D + +L Sbjct: 697 GTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLS 756 Query: 513 YSWQLWEGGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVI-TMLNSD 337 + E L++ + V+ +AR + A+ C++E RPTM + + T+L++D Sbjct: 757 AKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSCLEEDRSKRPTMEHAVQTLLSAD 816
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 56.6 bits (135), Expect = 7e-08 Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 2/109 (1%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY S K DV+S+GV+LLE+++GKR + + D NL+G+ Q Sbjct: 1048 GTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGD-NNLVGWVKQ-HAK 1105 Query: 489 GRCLELLEASVANEVHAAEAR--RYVNTALMCVQEHADDRPTMSNVITM 349 R ++ + + E A E +++ A+ C+ + A RPTM V+ M Sbjct: 1106 LRISDVFDPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAM 1154
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 2/109 (1%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY S K DV+S+GV+LLE+++GK+ + + D NL+G+ +L Sbjct: 1053 GTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGD-NNLVGWV-KLHAK 1110 Query: 489 GRCLELLEASVANEVHAAEAR--RYVNTALMCVQEHADDRPTMSNVITM 349 G+ ++ + + E + E +++ A C+ + RPTM V+ M Sbjct: 1111 GKITDVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAM 1159
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 2/109 (1%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY+ PEY S K DV+S+GV+LLE+++GK+ + + D NL+G+ +L Sbjct: 1053 GTPGYVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGD-NNLVGWV-KLHAK 1110 Query: 489 GRCLELLEASVANEVHAAEAR--RYVNTALMCVQEHADDRPTMSNVITM 349 G+ ++ + + E + E +++ A C+ + RPTM V+ M Sbjct: 1111 GKITDVFDRELLKEDASIEIELLQHLKVACACLDDRHWKRPTMIQVMAM 1159
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 53.5 bits (127), Expect = 6e-07 Identities = 32/108 (29%), Positives = 55/108 (50%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 G+ GY+ PEY S + KSDV+S GV+LLE+I+G+ + + E +++ + + Sbjct: 736 GSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTEK-VHISDHVRSILAN 794 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 G +++ + A + AL C + + RPTMS V+ L Sbjct: 795 GDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMEL 842
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 51.2 bits (121), Expect = 3e-06 Identities = 34/108 (31%), Positives = 55/108 (50%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YM+PE A +G + KSD++SFGV+LLEII+G + EH + LL ++ + Sbjct: 350 GTTAYMAPE-ALRGEITPKSDIYSFGVVLLEIITGL--PAVDEHREPQLLLDIKEEIEDE 406 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 + +E N+ + + A C+ E + RP + V +L Sbjct: 407 EKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLL 454
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 3/108 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR-NSSFHEHEDFLNLLGYSWQLWE 493 GT Y+ PE+ + S DV+SFG++LLE+ +G++ E+E NLL Y Q W Sbjct: 386 GTKIYLPPEFRNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKKNLLDYVKQQWR 445 Query: 492 GGRCLELLEASVANEV--HAAEARRYVNTALMCVQEHADDRPTMSNVI 355 R +ELLE +A + + L C DRP+M+ V+ Sbjct: 446 QNR-MELLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVL 492
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 49.7 bits (117), Expect = 8e-06 Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISG-KRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 YM EY QG SVK+DV+SFG++++E+++G K +H +LL + C Sbjct: 353 YMPEEYIRQGRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHVQLRDLLMELMEKRGLDSC 412 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNS 340 L L+ + A+ + + A CV A RPTM V++ L S Sbjct: 413 LSFLDRKIPPCPRNFSAKLF-SLAGRCVATKAKLRPTMDEVLSSLES 458
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 49.7 bits (117), Expect = 8e-06 Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 G+ GY++PEY + KSD++SFGV+LLE+++GK+ + + + W Sbjct: 860 GSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTDSELGDKDM----AKWVCTAL 915 Query: 489 GRC-LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLP 322 +C LE + + E + ++ L+C +RP+M V+ ML S +P Sbjct: 916 DKCGLEPVIDPKLDLKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEVSGAVP 972
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/112 (29%), Positives = 58/112 (51%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YM+PE A +G + KSD++SFGV+LLE+I+G ++ E+ + LL ++ + Sbjct: 350 GTTAYMAPE-ALRGEITPKSDIYSFGVVLLELITGL--AAVDENREPQLLLDIKEEIEDE 406 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDS 334 + +E ++ A + A C+ E + RP ++ V +L S Sbjct: 407 EKTIEDYTDEKMSDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEMS 458
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 46.2 bits (108), Expect = 9e-05 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 1/112 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR-NSSFHEHEDFLNLLGYSWQLWEGGRC 481 YM EY QG S+K+DV+SFG++++E+++G R +H +LL + C Sbjct: 340 YMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSC 399 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVL 325 L L+ V A+ + A C A RP+M V+ L S L Sbjct: 400 LSFLDKKVPPCPRNFSAKLFC-LAGRCAATRAKLRPSMDEVLNTLESTQASL 450
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 42.7 bits (99), Expect = 0.001 Identities = 24/50 (48%), Positives = 31/50 (62%), Gaps = 2/50 (4%) Frame = -3 Query: 663 YGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR--NSSFHEHEDFLNL 520 Y + +PE S+G YS+KSDV+SFGVLL EI S + HE FL + Sbjct: 351 YKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRV 400
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 42.4 bits (98), Expect = 0.001 Identities = 29/108 (26%), Positives = 51/108 (47%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT GY +PE + +Y K D+FS+G++L E++SG+R + H L + +L +G Sbjct: 1449 GTPGYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRPALGHHQ------LQIAKKLSKG 1502 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 R V + + RR + C + RP +V++ + Sbjct: 1503 IR-------PVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQM 1543
>STE7_YEAST (P06784) Serine/threonine-protein kinase STE7 (EC 2.7.12.2)| Length = 515 Score = 42.4 bits (98), Expect = 0.001 Identities = 16/36 (44%), Positives = 27/36 (75%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE +YS+K DV+S G++++E+++G+ Sbjct: 366 GTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGE 401
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 42.4 bits (98), Expect = 0.001 Identities = 20/36 (55%), Positives = 26/36 (72%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GTY +M PE S YS SDV+S+GVLL E+I+G+ Sbjct: 307 GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGE 342
>YS3J_CAEEL (Q19238) Putative tyrosine-protein kinase F09A5.2 in chromosome X (EC| 2.7.10.1) Length = 894 Score = 42.4 bits (98), Expect = 0.001 Identities = 45/147 (30%), Positives = 59/147 (40%), Gaps = 10/147 (6%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 +MS E +S K+DV+SFGVLL EI S G + D L L GGR Sbjct: 694 WMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLE------HLLAGGRL 747 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMS----NVITMLNSDS-----VV 328 + L+ NE+ N C E +DRP + + MLN D + Sbjct: 748 SQPLKC--PNEI--------FNIMQKCWAEKPEDRPEFNEMRGEITVMLNLDDESYGYLS 797 Query: 327 LPKPNHPAYFNLMASKEDESAPCSYNG 247 + P Y L E+APCS G Sbjct: 798 VESQGGPKYTQLTMQDSKETAPCSTPG 824
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 42.4 bits (98), Expect = 0.001 Identities = 33/108 (30%), Positives = 50/108 (46%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT + +PE Y K+DVFSFGV++ E+++GK F E N + S + EG Sbjct: 1522 GTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGK--EPFAE----CNFMKVSLDILEG 1575 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 GR ++ + +E + C A RPTM+ V+ L Sbjct: 1576 GR--PIIPSDCPHE--------FAKLIKKCWHAKAHKRPTMTEVVQQL 1613
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 42.4 bits (98), Expect = 0.001 Identities = 18/36 (50%), Positives = 27/36 (75%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GTY +M+PE ++S SDV+SFGVLL E+++G+ Sbjct: 265 GTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGE 300
>BYR1_SCHPO (P10506) Protein kinase byr1 (EC 2.7.12.2) (MAPK kinase) (MAPKK)| Length = 340 Score = 42.0 bits (97), Expect = 0.002 Identities = 20/51 (39%), Positives = 32/51 (62%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLL 517 GT YMSPE G Y+VKSD++S G+ ++E+ + + SF +D + +L Sbjct: 221 GTSTYMSPERIRGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGIL 271
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 42.0 bits (97), Expect = 0.002 Identities = 18/42 (42%), Positives = 29/42 (69%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFH 544 GT GY +PE + +Y K D+FS+G++L E++SG+R + H Sbjct: 1426 GTPGYQAPEIRPRIVYDEKVDMFSYGMVLYELLSGQRPALGH 1467
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 41.2 bits (95), Expect = 0.003 Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 5/104 (4%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFH-EHEDFLNLLGYSWQLWE 493 GT Y+ EY G +V +D FSFGV++LE ++G+R H +L L + E Sbjct: 386 GTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDL-VEEEAEE 444 Query: 492 GGRCL----ELLEASVANEVHAAEARRYVNTALMCVQEHADDRP 373 G L L+A +A + AA A+ ++H D RP Sbjct: 445 AGVALRSTQSTLQAGLAADAWAAP------IAMQIYKKHLDPRP 482
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 41.2 bits (95), Expect = 0.003 Identities = 18/36 (50%), Positives = 26/36 (72%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GTY +M+PE +S SDV+SFGVLL E+++G+ Sbjct: 284 GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGE 319
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 41.2 bits (95), Expect = 0.003 Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL EI++ GK + D ++ L +++ C Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENC 467 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 + L + MC +E A++RPT + ++L+ Sbjct: 468 PDEL----------------YDIMKMCWKEKAEERPTFDYLQSVLD 497
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 41.2 bits (95), Expect = 0.003 Identities = 16/36 (44%), Positives = 27/36 (75%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GTY +M+PE ++S SD++S+GVLL E+++G+ Sbjct: 306 GTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGE 341
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL EI++ GK + D + L +++ C Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENC 467 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 + L + MC +E A++RPT + ++L+ Sbjct: 468 PDEL----------------YDIMKMCWKESAEERPTFDYLQSVLD 497
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL EI++ GK + D + L +++ C Sbjct: 408 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENC 467 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 + L + MC +E A++RPT + ++L+ Sbjct: 468 PDEL----------------YDIMKMCWKEKAEERPTFDYLQSVLD 497
>MKK1_YEAST (P32490) MAP kinase kinase MKK1/SSP32 (EC 2.7.12.2)| Length = 508 Score = 40.8 bits (94), Expect = 0.004 Identities = 28/105 (26%), Positives = 53/105 (50%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YM+PE YSV SDV+S G+ +LE+ +GK S + N+ + +W Sbjct: 384 GTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGKFPCS--SEKMAANIAPFELLMWIL 441 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVI 355 EL + +N + + + +++ C+++ + +RP+ +I Sbjct: 442 TFTPELKDEPESNIIWSPSFKSFID---YCLKKDSRERPSPRQMI 483
>FLT3_MOUSE (Q00342) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) Length = 992 Score = 40.4 bits (93), Expect = 0.005 Identities = 17/30 (56%), Positives = 25/30 (83%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +GIY++KSDV+S+G+LL EI S Sbjct: 857 WMAPESLFEGIYTIKSDVWSYGILLWEIFS 886
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 40.4 bits (93), Expect = 0.005 Identities = 17/30 (56%), Positives = 25/30 (83%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +GIY++KSDV+S+G+LL EI S Sbjct: 854 WMAPESLFEGIYTIKSDVWSYGILLWEIFS 883
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 40.4 bits (93), Expect = 0.005 Identities = 17/36 (47%), Positives = 27/36 (75%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GTY +M+PE ++S SDV+S+GVLL E+++G+ Sbjct: 311 GTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGE 346
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 40.4 bits (93), Expect = 0.005 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 1/105 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 +M+PE GI++ +SDV+SFG+L+ EI++ G + H + D LN + +L C Sbjct: 2127 WMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNC 2186 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 + L N C + D RPT + L Sbjct: 2187 PDDL----------------WNLMTQCWAQEPDQRPTFHRIQNQL 2215
>FUZ7_USTMA (Q99078) Dual specificity protein kinase FUZ7 (EC 2.7.12.2)| Length = 435 Score = 40.0 bits (92), Expect = 0.006 Identities = 20/46 (43%), Positives = 29/46 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHED 532 GT YMSPE YSVKSDV+S GV ++++ G+ + +E +D Sbjct: 266 GTSTYMSPERIQGDQYSVKSDVWSLGVSIIDVALGRFPFAENEEDD 311
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 40.0 bits (92), Expect = 0.006 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y+ EY G +V +D FSFGV++LE ++G+R Sbjct: 386 GTLAYLPEEYIKTGRLAVDTDTFSFGVVILETLAGQR 422
>JAK3_HUMAN (P52333) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) (Leukocyte janus kinase) (L-JAK) Length = 1124 Score = 39.7 bits (91), Expect = 0.008 Identities = 30/98 (30%), Positives = 45/98 (45%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEGGRCL 478 + +PE S I+S +SDV+SFGV+L E+ + + S +FL ++G + R L Sbjct: 993 WYAPESLSDNIFSRQSDVWSFGVVLYELFT-YCDKSCSPSAEFLRMMGCERDVPALCRLL 1051 Query: 477 ELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMS 364 ELLE A +C DRP+ S Sbjct: 1052 ELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFS 1089
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 39.7 bits (91), Expect = 0.008 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 4/137 (2%) Frame = -3 Query: 660 GYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR-NSSFHEHEDFLNLLGYSWQLWEGGR 484 GY +PE + +SDV++FG+LLLEI+ GK+ S +F++L Sbjct: 541 GYKAPELHKMKKCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLEET 600 Query: 483 CLELLEASVANEVHAAEARRYVNT---ALMCVQEHADDRPTMSNVITMLNSDSVVLPKPN 313 +E+ + + + V+ A+ C RP+M V+ L + P+ N Sbjct: 601 TMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQLEENR---PR-N 656 Query: 312 HPAYFNLMASKEDESAP 262 A ++ ++ D P Sbjct: 657 RSALYSPTETRSDAETP 673
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 39.7 bits (91), Expect = 0.008 Identities = 18/36 (50%), Positives = 25/36 (69%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YM+PE S YS+ +D +SFGVLL E ++G+ Sbjct: 532 GTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQ 567
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 39.7 bits (91), Expect = 0.008 Identities = 20/46 (43%), Positives = 31/46 (67%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGI-YSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE S+G Y +D FSFG +L +++ G +S F +H+ Sbjct: 353 GTHGYMAPEVLSKGTSYDSCADWFSFGCMLYKLLKG--HSPFRQHK 396
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 39.7 bits (91), Expect = 0.008 Identities = 22/50 (44%), Positives = 30/50 (60%), Gaps = 2/50 (4%) Frame = -3 Query: 663 YGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR--NSSFHEHEDFLNL 520 Y + +PE S+G YS KSDV+SFG+LL E+ S + HE FL + Sbjct: 351 YKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRV 400
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 39.3 bits (90), Expect = 0.011 Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE +S+KSDV+SFG+LL EII+ GK S + +L +++L + C Sbjct: 399 WTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNC 458 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNV 358 +++ N L C +RPT + Sbjct: 459 ----------------PQQFYNIMLECWNAEPKERPTFETL 483
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 39.3 bits (90), Expect = 0.011 Identities = 25/106 (23%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL+EI++ G+ + + + L + +++ C Sbjct: 420 WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNC 479 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 E L N + C + ++RPT + ++L+ Sbjct: 480 PEEL----------------YNIMIRCWKNRPEERPTFEYIQSVLD 509
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 38.9 bits (89), Expect = 0.014 Identities = 18/46 (39%), Positives = 31/46 (67%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGI-YSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE ++G+ Y +D FS G +L +++ G +S F +H+ Sbjct: 353 GTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLLKG--HSPFRQHK 396
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 38.9 bits (89), Expect = 0.014 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL EI++ G+ + + + L +++ C Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNC 464 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 E L + ++C +E +DRPT + ++L+ Sbjct: 465 PEEL----------------YHLMMLCWKERPEDRPTFDYLRSVLD 494
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 38.5 bits (88), Expect = 0.019 Identities = 26/105 (24%), Positives = 51/105 (48%), Gaps = 1/105 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL EI++ G+ + + + L +++ C Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNC 464 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 E L + ++C +E +DRPT + ++L Sbjct: 465 PEEL----------------YHLMMLCWKERPEDRPTFDYLRSVL 493
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 38.5 bits (88), Expect = 0.019 Identities = 18/36 (50%), Positives = 22/36 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT GYM+PE Y+ D FSFG LL E+I G+ Sbjct: 471 GTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQ 506
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 38.5 bits (88), Expect = 0.019 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGI-YSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G+ Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 38.5 bits (88), Expect = 0.019 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGI-YSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G+ Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 38.5 bits (88), Expect = 0.019 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGI-YSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G+ Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 38.5 bits (88), Expect = 0.019 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGI-YSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G+ Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 38.5 bits (88), Expect = 0.019 Identities = 18/46 (39%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGI-YSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G+ Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>PKN2_BACSU (O34507) Probable serine/threonine-protein kinase yloP (EC| 2.7.11.1) Length = 648 Score = 38.5 bits (88), Expect = 0.019 Identities = 14/36 (38%), Positives = 27/36 (75%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 G+ Y+SPE A G+ + KSD+++ G++L E+++G+ Sbjct: 172 GSVHYLSPEQARGGLATKKSDIYALGIVLFELLTGR 207
>NEK9_HUMAN (Q8TD19) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8) Length = 979 Score = 38.1 bits (87), Expect = 0.024 Identities = 26/105 (24%), Positives = 49/105 (46%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YMSPE Y+ KSD+++ G ++ E+++ KR D N L ++ +G Sbjct: 213 GTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTF------DATNPLNLCVKIVQG 266 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVI 355 R +E+ + + E+ + C+ + + RPT ++ Sbjct: 267 IRAMEVDSSQYSLEL--------IQMVHSCLDQDPEQRPTADELL 303
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 38.1 bits (87), Expect = 0.024 Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 1/131 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 +M+PE G+++ SD++SFGV+L EI S ++ +E L + L + C Sbjct: 1202 WMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNC 1261 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLPKPNHPAY 301 E R + MC Q + RPT ++ +L D + P ++ Sbjct: 1262 PE----------------RVTDLMRMCWQFNPKMRPTFLEIVNLLKDD--LHPSFPEVSF 1303 Query: 300 FNLMASKEDES 268 F+ +K ES Sbjct: 1304 FHSEENKAPES 1314
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 38.1 bits (87), Expect = 0.024 Identities = 23/49 (46%), Positives = 28/49 (57%), Gaps = 2/49 (4%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS--GKRNSSFHEHEDFLNLL 517 +M+PE IYS KSDV+S+GVLL EI S G EDF + L Sbjct: 1065 WMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRL 1113
>TNK1_MOUSE (Q99ML2) Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2)| (Kinase of embryonic stem cells) Length = 666 Score = 38.1 bits (87), Expect = 0.024 Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 4/110 (3%) Frame = -3 Query: 663 YGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEGGR 484 Y + +PE QG +S SDV+ FGV L E+ SG + W G Sbjct: 287 YAWCAPESLRQGAFSSASDVWMFGVTLWEMFSGGE------------------EPWAGVP 328 Query: 483 CLELLEASVANEVHAAE----ARRYVNTALMCVQEHADDRPTMSNVITML 346 +L+ + + +R + AL C H DRP+ SN+ +L Sbjct: 329 PYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLL 378
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 38.1 bits (87), Expect = 0.024 Identities = 15/36 (41%), Positives = 26/36 (72%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YM+PE + Y++ SD++SFG+ L+E++ G+ Sbjct: 230 GTRSYMAPERLTGSHYTISSDIWSFGLSLVELLIGR 265
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 37.7 bits (86), Expect = 0.032 Identities = 34/119 (28%), Positives = 52/119 (43%), Gaps = 5/119 (4%) Frame = -3 Query: 669 GTYGYMSPEYASQG-IYSVKSDVFSFGVLLLEII-SGKR---NSSFHEHEDFLNLLGYSW 505 GT G+ +PE A IY+ ++DV+SFG+LL +I+ +G R F D L + G Sbjct: 2034 GTPGFRAPEVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDELEIQGKL- 2092 Query: 504 QLWEGGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVV 328 E A C++E+ +RPT + V +LNS +V Sbjct: 2093 -------------PDPVKEYGCAPWPMVEKLIKQCLKENPQERPTSAQVFDILNSAELV 2138
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 37.7 bits (86), Expect = 0.032 Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 2/49 (4%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS--GKRNSSFHEHEDFLNLL 517 +M+PE +YS KSDV+S+GVLL EI S G EDF + L Sbjct: 1065 WMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRL 1113
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 37.7 bits (86), Expect = 0.032 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+L+ EI++ G+ + + + L +++ C Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILMTEIVTHGRIPYPGMTNPEVIQNLERGYRMPRPDNC 464 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 E L + C +E DDRPT + ++L Sbjct: 465 PEEL----------------YKLMMQCWRERPDDRPTFDYLRSVL 493
>STE7_CANAL (P46599) Serine/threonine-protein kinase STE7 homolog (EC 2.7.12.2)| Length = 589 Score = 37.7 bits (86), Expect = 0.032 Identities = 19/35 (54%), Positives = 24/35 (68%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 GT YMSPE Y VKSDV+S G++L+E+ SG Sbjct: 411 GTSMYMSPERIQGLDYGVKSDVWSTGLMLIELASG 445
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 37.7 bits (86), Expect = 0.032 Identities = 37/144 (25%), Positives = 58/144 (40%), Gaps = 1/144 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 +MSPE G+++ SDV+SFGV+L EI S ++ +E L + L C Sbjct: 1191 WMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDHPENC 1250 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLPKPNHPAY 301 L + + MC Q + RPT +I ML D P++ Sbjct: 1251 PPRLHSLMQ----------------MCWQYNPKMRPTFLEIIDMLKDDL-------RPSF 1287 Query: 300 FNLMASKEDESAPCSYNGVTITVE 229 ++ DE+ P + + I E Sbjct: 1288 QDVSFYYSDENKPPETDDLEIDFE 1311
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 37.7 bits (86), Expect = 0.032 Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 2/49 (4%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS--GKRNSSFHEHEDFLNLL 517 +M+PE +YS KSDV+S+GVLL EI S G EDF + L Sbjct: 1065 WMAPESIFDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRL 1113
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 37.4 bits (85), Expect = 0.041 Identities = 29/105 (27%), Positives = 48/105 (45%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YMSPE YS KSD+++ G +L E+++ R D N L ++ +G Sbjct: 195 GTLYYMSPEICQGVKYSFKSDIWAVGCVLYELLTLTRTF------DATNPLNLCVKIVQG 248 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVI 355 + L N V+ E V+ C+++ + RPT ++ Sbjct: 249 NWAVGL-----DNTVYTQELIEVVHA---CLEQDPEKRPTADEIL 285
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 37.4 bits (85), Expect = 0.041 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL+EI++ G+ + + + L +++ C Sbjct: 422 WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENC 481 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 E L N + C + ++RPT + ++L+ Sbjct: 482 PEEL----------------YNIMMRCWKNRPEERPTFEYIQSVLD 511
>CCAMK_PEA (Q6RET6) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (PsCCaMK) (Ps-SYM9) (Fragment) Length = 527 Score = 37.4 bits (85), Expect = 0.041 Identities = 17/35 (48%), Positives = 25/35 (71%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 G+ Y+SPE SQG + KSD++S GV+L ++SG Sbjct: 218 GSIDYVSPEALSQGKITTKSDMWSLGVILYILLSG 252
>LIN2_CAEEL (P54936) Protein lin-2 (Abnormal cell lineage protein 2)| Length = 961 Score = 37.4 bits (85), Expect = 0.041 Identities = 32/133 (24%), Positives = 62/133 (46%), Gaps = 23/133 (17%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK-----RNSSFHEH--EDFLNLLGY 511 G +M+PE + S SD++S GV+L +++G+ S +E + +++ GY Sbjct: 187 GVPQFMAPEIVRKDRVSCSSDIWSSGVVLFLLLAGRLPFSGSTSDIYERIMQTDVDVDGY 246 Query: 510 SWQLWEGGRCL--ELLEASVANEVHAAEA--------------RRYVNTALMCVQEHADD 379 + E R L +L A + + A EA R+++N + ++ + + Sbjct: 247 MPNISESARNLVRRMLNADPSKRISAKEALNHEWIRDKEHMASRKHMNDVIDQMRRYNES 306 Query: 378 RPTMSNVITMLNS 340 R SNV++ +NS Sbjct: 307 RKLKSNVLSAVNS 319
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 37.4 bits (85), Expect = 0.041 Identities = 24/106 (22%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G +++KSDV+SFG+LL+EI++ G+ + + + L + +++ C Sbjct: 399 WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNC 458 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 E L + + C + ++RPT + ++L+ Sbjct: 459 PEEL----------------YSIMIRCWKNRPEERPTFEYIQSVLD 488
>CCAMK_MEDTR (Q6RET7) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase DMI-3 (EC 2.7.11.17) (Does not make infections protein 3) (CCaMK DMI3) (MtCCaMK) Length = 523 Score = 37.4 bits (85), Expect = 0.041 Identities = 17/35 (48%), Positives = 25/35 (71%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 G+ Y+SPE SQG + KSD++S GV+L ++SG Sbjct: 210 GSIDYVSPEALSQGKITTKSDMWSLGVILYILLSG 244
>MP2K2_CYPCA (Q90321) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 397 Score = 37.0 bits (84), Expect = 0.054 Identities = 18/36 (50%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SDV+S G+ L+E+ G+ Sbjct: 226 GTRSYMSPERLQGTHYSVQSDVWSMGLSLVELAIGR 261
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 37.0 bits (84), Expect = 0.054 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQG-IYSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 37.0 bits (84), Expect = 0.054 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQG-IYSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 37.0 bits (84), Expect = 0.054 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQG-IYSVKSDVFSFGVLLLEIISGKRNSSFHEHE 535 GT+GYM+PE +G Y +D FS G +L +++ G +S F +H+ Sbjct: 352 GTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRG--HSPFRQHK 395
>PKN1_THETN (Q8R9T6) Probable serine/threonine-protein kinase Sps1 (EC| 2.7.11.1) Length = 625 Score = 37.0 bits (84), Expect = 0.054 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT Y SPE A I ++D++S G++L E+++GK Sbjct: 172 GTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLTGK 207
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 37.0 bits (84), Expect = 0.054 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 1/108 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 +MSPE G+++ SD++SFGV+L EI S ++ +E L + L C Sbjct: 1203 WMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNC 1262 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSD 337 E R + MC Q + RPT ++ +L D Sbjct: 1263 PE----------------RLTDLMRMCWQFNPKMRPTFLEIVNLLKDD 1294
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 37.0 bits (84), Expect = 0.054 Identities = 33/141 (23%), Positives = 56/141 (39%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 G+ +M+PE YS K DVFS+G++L E+I+ R F E W + G Sbjct: 191 GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVIT--RRKPFDEIGG--PAFRIMWAVHNG 246 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLPKPNH 310 R L ++ + + R C + RP+M ++ ++ P + Sbjct: 247 TR--PPLIKNLPKPIESLMTR--------CWSKDPSQRPSMEEIVKIMTHLMRYFPGADE 296 Query: 309 PAYFNLMASKEDESAPCSYNG 247 P + S E +S + G Sbjct: 297 PLQYPCQYSDEGQSNSATSTG 317
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 37.0 bits (84), Expect = 0.054 Identities = 30/106 (28%), Positives = 44/106 (41%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEGGRCL 478 +M+PE +Y+++SDV+SFGVLL EI S L Y + C Sbjct: 1069 WMAPETIFDRVYTIQSDVWSFGVLLWEIFS-------------LGASPYPGVKIDEEFCR 1115 Query: 477 ELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNS 340 L E + Y T L C E + RP+ S ++ L + Sbjct: 1116 RLKEGTRMRAPDYTTPEMY-QTMLDCWHEDPNQRPSFSELVEHLGN 1160
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 37.0 bits (84), Expect = 0.054 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 2/106 (1%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS--GKRNSSFHEHEDFLNLLGYSWQLWEGGR 484 +M+PE IY+ +SDV+SFGVL+ EI S H E+F Sbjct: 1046 WMAPEAIFDKIYTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEEF--------------- 1090 Query: 483 CLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 C L E + + + Y T L C RPT + ++ L Sbjct: 1091 CCRLKEGTRMKAPEYSSSEIY-QTMLDCWHGEPSQRPTFTELVERL 1135
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 37.0 bits (84), Expect = 0.054 Identities = 29/108 (26%), Positives = 45/108 (41%), Gaps = 1/108 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 +MSPE G+++ SD++SFGV+L EI S ++ +E L + L C Sbjct: 1192 WMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNC 1251 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSD 337 E R + MC Q + RPT ++ +L D Sbjct: 1252 PE----------------RLTDLMRMCWQFNPKMRPTFLEIVNLLKDD 1283
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 37.0 bits (84), Expect = 0.054 Identities = 33/141 (23%), Positives = 56/141 (39%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 G+ +M+PE YS K DVFS+G++L E+I+ R F E W + G Sbjct: 191 GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVIT--RRKPFDEIGG--PAFRIMWAVHNG 246 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVVLPKPNH 310 R L ++ + + R C + RP+M ++ ++ P + Sbjct: 247 TR--PPLIKNLPKPIESLMTR--------CWSKDPSQRPSMEEIVKIMTHLMRYFPGADE 296 Query: 309 PAYFNLMASKEDESAPCSYNG 247 P + S E +S + G Sbjct: 297 PLQYPCQYSDEGQSNSATSTG 317
>MP2K2_RAT (P36506) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 36.6 bits (83), Expect = 0.071 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 229 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGR 264
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 36.6 bits (83), Expect = 0.071 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE + G +++KSDV+SFG+LL EI++ R Sbjct: 405 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR 437
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 36.6 bits (83), Expect = 0.071 Identities = 19/58 (32%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRN-SSFHEHEDFLNLLGYSWQL 499 GT Y+SPE S I SD+++FG +L ++++GK + +E+ F ++L S+++ Sbjct: 274 GTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEI 331
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 36.6 bits (83), Expect = 0.071 Identities = 16/35 (45%), Positives = 23/35 (65%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 GT Y+SPE G +SDV+S GVL+ E+++G Sbjct: 180 GTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 36.6 bits (83), Expect = 0.071 Identities = 16/35 (45%), Positives = 23/35 (65%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 GT Y+SPE G +SDV+S GVL+ E+++G Sbjct: 180 GTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTG 214
>NEK9_MOUSE (Q8K1R7) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) Length = 984 Score = 36.6 bits (83), Expect = 0.071 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 8/118 (6%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YMSPE Y+ KSD+++ G ++ E+++ KR D N L ++ +G Sbjct: 213 GTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLTLKRTF------DATNPLNLCVKIVQG 266 Query: 489 GRCLELLEASVANE----VHAA----EARRYVNTALMCVQEHADDRPTMSNVITMLNS 340 R +E+ + + E VHA +R AL+ + R M +T+LN+ Sbjct: 267 IRAMEVDSSQYSLELIQLVHACLDQDPEQRPAADALLDLPLLRTRRREMEEKVTLLNA 324
>MP2K2_MOUSE (Q63932) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 401 Score = 36.6 bits (83), Expect = 0.071 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 229 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGR 264
>SKH1_SCHPO (Q9Y884) MAP kinase kinase skh1/pek1 (EC 2.7.12.2)| Length = 363 Score = 36.6 bits (83), Expect = 0.071 Identities = 15/32 (46%), Positives = 23/32 (71%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEI 574 GT YM+PE S G Y++ SD++S G+ L+E+ Sbjct: 241 GTSYYMAPERISGGSYTISSDIWSLGLTLMEV 272
>IKKB_DROME (Q9VEZ5) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (DmIKK-beta) (Immune response deficient protein 5) (IKK-like protein) (Lipopolysaccharide-activated kinase) (DLAK) (Cactus kinase IKK) Length = 751 Score = 36.6 bits (83), Expect = 0.071 Identities = 17/51 (33%), Positives = 29/51 (56%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLL 517 GT Y +PE G Y+ D++SFGV+ E+++G+ F H+ N++ Sbjct: 224 GTRHYYAPEVVENGFYNSTVDLWSFGVIAYELVTGE--LPFIPHQTLKNII 272
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 36.6 bits (83), Expect = 0.071 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+IS R Sbjct: 447 WTAPEAALFGRFTIKSDVWSFGILLTELISKGR 479
>MP2K2_CHICK (Q90891) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 398 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 227 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGR 262
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 36.2 bits (82), Expect = 0.092 Identities = 18/49 (36%), Positives = 30/49 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLN 523 GT GYM+PE S Y+ D + G L+ E+I+G +S F ++++ +N Sbjct: 347 GTVGYMAPEIISHEKYTFSPDWWGLGCLIYEMIAG--HSPFRKYKEKVN 393
>MP2K1_CRIGR (Q63980) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 393 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 225 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 260
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 36.2 bits (82), Expect = 0.092 Identities = 24/109 (22%), Positives = 50/109 (45%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 G+ +M+PE Y+ K D+FS+ ++L E++S K+ + N W++++G Sbjct: 175 GSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQ-----PFKGIDNAYTIQWKIYKG 229 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 R L +R + C + +DRP+M ++ +++ Sbjct: 230 ERPPLLTTC----------PKRIEDLMTACWKTVPEDRPSMQYIVGVMH 268
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 36.2 bits (82), Expect = 0.092 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+++SDV+SFGVLL EI S Sbjct: 1064 WMAPETIFDRVYTIQSDVWSFGVLLWEIFS 1093
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 36.2 bits (82), Expect = 0.092 Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 8/66 (12%) Frame = -3 Query: 669 GTYGYMSPE--YASQGIYSVKSDVFSFGVLLLEIISGKRNSSFH--EHEDFLNLL----G 514 G+ YM+PE Y+ +G Y+ ++D++S G+LL +++G+ E+EDF+ + Sbjct: 182 GSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIENDGN 241 Query: 513 YSWQLW 496 +W W Sbjct: 242 LNWGPW 247
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 36.2 bits (82), Expect = 0.092 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI--ISGKRNSSFHEHEDFLNLLGYSWQLWEGGR 484 +M+PE +Y+ SDV+SFG+LL EI + G +E F N + +++ Sbjct: 869 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRM----- 923 Query: 483 CLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 A HA++ C +E + RP S ++ +L Sbjct: 924 ---------AQPAHASD--EIYEIMQKCWEEKFEIRPPFSQLVLLL 958
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 36.2 bits (82), Expect = 0.092 Identities = 13/30 (43%), Positives = 25/30 (83%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE G++++K+DV+SFGVLL+E+++ Sbjct: 400 WTAPEAIHFGVFTIKADVWSFGVLLMEVVT 429
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 36.2 bits (82), Expect = 0.092 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI--ISGKRNSSFHEHEDFLNLLGYSWQLWEGGR 484 +M+PE +Y+ SDV+SFG+LL EI + G +E F N + +++ Sbjct: 869 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRM----- 923 Query: 483 CLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 A HA++ C +E + RP S ++ +L Sbjct: 924 ---------AQPAHASD--EIYEIMQKCWEEKFEIRPPFSQLVLLL 958
>MP2K1_RAT (Q01986) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>MP2K1_RABIT (P29678) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>MP2K1_MOUSE (P31938) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>MP2K1_HUMAN (Q02750) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 392 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR 259
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 36.2 bits (82), Expect = 0.092 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+++SDV+SFGVLL EI S Sbjct: 1071 WMAPETIFDRVYTIQSDVWSFGVLLWEIFS 1100
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 36.2 bits (82), Expect = 0.092 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE + G +++KSDV+SFG+LL EI++ Sbjct: 404 WTAPEAINYGTFTIKSDVWSFGILLTEIVT 433
>MP2K1_SERCA (Q91447) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) (Fragment) Length = 388 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 218 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAIGR 253
>MP2K1_XENLA (Q05116) Dual specificity mitogen-activated protein kinase kinase 1| (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK 1) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK1) Length = 394 Score = 36.2 bits (82), Expect = 0.092 Identities = 17/36 (47%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YMSPE YSV+SD++S G+ L+E+ G+ Sbjct: 224 GTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAIGR 259
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI--ISGKRNSSFHEHEDFLNLLGYSWQLWEGGR 484 +M+PE +Y+ SDV+SFG+LL EI + G ++ F N + +++ Sbjct: 868 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRM----- 922 Query: 483 CLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 A HA++ C +E + RP S ++ +L Sbjct: 923 ---------AQPAHASD--EIYEIMQKCWEEKFETRPPFSQLVLLL 957
>NEK7_HUMAN (Q8TDX7) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 35.8 bits (81), Expect = 0.12 Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 3/107 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YMSPE + Y+ KSD++S G LL E+ + S F + D +NL YS Sbjct: 198 GTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA--LQSPF--YGDKMNL--YS------ 245 Query: 489 GRCLELLEAS---VANEVHAAEARRYVNTALMCVQEHADDRPTMSNV 358 C ++ + + ++ ++ E R+ VN MC+ + RP ++ V Sbjct: 246 -LCKKIEQCDYPPLPSDHYSEELRQLVN---MCINPDPEKRPDVTYV 288
>LRRK2_MOUSE (Q5S006) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) Length = 2527 Score = 35.8 bits (81), Expect = 0.12 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 2/116 (1%) Frame = -3 Query: 669 GTYGYMSPEYASQG-IYSVKSDVFSFGVLLLEI-ISGKRNSSFHEHEDFLNLLGYSWQLW 496 GT G+ +PE A IY+ ++DV+SFG+LL +I +G R + + L +L Sbjct: 2034 GTPGFRAPEVARGNVIYNQQADVYSFGLLLHDIWTTGSRIMEGLRFPNEFDELAIQGKL- 2092 Query: 495 EGGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNSDSVV 328 E A C++E+ +RPT + V +LNS ++ Sbjct: 2093 ----------PDPVKEYGCAPWPMVEKLITKCLKENPQERPTSAQVFDILNSAELI 2138
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 467
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/32 (46%), Positives = 23/32 (71%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEI 574 GTY +M+PE + Y+ K DV+SFG++L E+ Sbjct: 248 GTYRWMAPEMIKEKPYTRKVDVYSFGIVLWEL 279
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVAKGR 463
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 460
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 463
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 463
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 431 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 463
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 35.8 bits (81), Expect = 0.12 Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 8/132 (6%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 +M+ E I+SVKSD++SFG+L+ EI++ G D + + ++L + C Sbjct: 653 WMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHC 712 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNS------DSVVLPK 319 R N C +RP + +I ML+ D + L + Sbjct: 713 ----------------RRELYNIMYYCWSHDPQERPLFAEIIQMLDKLLHTEMDYIELER 756 Query: 318 -PNHPAYFNLMA 286 P+H Y+N+++ Sbjct: 757 FPDH-NYYNIVS 767
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 438 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 470
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 35.8 bits (81), Expect = 0.12 Identities = 22/49 (44%), Positives = 30/49 (61%), Gaps = 1/49 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFH-EHEDFL 526 GT Y+SPE +Y+ D +SFGVL+ E++ G+ S FH E ED L Sbjct: 537 GTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQ--SPFHGEGEDEL 583
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE GI++ SDV+SFGV+L EI++ Sbjct: 1158 WMAPESLKDGIFTTHSDVWSFGVVLWEIVT 1187
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE GI++ SDV+SFGV+L EI++ Sbjct: 1158 WMAPESLKDGIFTTHSDVWSFGVVLWEIVT 1187
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 460
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 428 WTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 460
>PKN2_MYXXA (P54736) Serine/threonine-protein kinase pkn2 (EC 2.7.11.1)| Length = 830 Score = 35.8 bits (81), Expect = 0.12 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT Y+SPE A +SD++SFGVL ++SG+ Sbjct: 179 GTPEYLSPEQAVGAKVDTRSDLYSFGVLTYRVLSGR 214
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 35.8 bits (81), Expect = 0.12 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI--ISGKRNSSFHEHEDFLNLLGYSWQLWEGGR 484 +M+PE +Y+ SDV+SFG+LL EI + G ++ F N + +++ Sbjct: 868 WMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQFYNAIKRGYRM----- 922 Query: 483 CLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 A HA++ C +E + RP S ++ +L Sbjct: 923 ---------AQPAHASD--EIYEIMQKCWEEKFETRPPFSQLVLLL 957
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 35.8 bits (81), Expect = 0.12 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G ++VKSDV+SFG+LL E+I+ R Sbjct: 412 WTAPEAALFGRFTVKSDVWSFGILLTELITKGR 444
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE GI++ SDV+SFGV+L EI++ Sbjct: 1158 WMAPESLKDGIFTTHSDVWSFGVVLWEIVT 1187
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/28 (57%), Positives = 20/28 (71%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +M PE G+YS SDVFSFGV+L E+ Sbjct: 1562 WMPPESLRDGVYSSASDVFSFGVVLWEM 1589
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+ E + +Y+ KSDV+SFGVLL EI+S Sbjct: 1015 WMAIESLNYSVYTTKSDVWSFGVLLWEIVS 1044
>MP2K2_HUMAN (P36507) Dual specificity mitogen-activated protein kinase kinase 2| (EC 2.7.12.2) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2) Length = 400 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/36 (44%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YM+PE YSV+SD++S G+ L+E+ G+ Sbjct: 229 GTRSYMAPERLQGTHYSVQSDIWSMGLSLVELAVGR 264
>KPK2_PLAFK (Q02595) Probable serine/threonine-protein kinase 2 (EC 2.7.11.1)| Length = 510 Score = 35.4 bits (80), Expect = 0.16 Identities = 15/35 (42%), Positives = 21/35 (60%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 G+ GY++PE Y K D+FS GV+L I+ G Sbjct: 268 GSPGYVAPEILKCASYGTKVDIFSLGVILFNILCG 302
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+ E + +Y+ KSDV+SFGVLL EI+S Sbjct: 65 WMAIESLNYSVYTTKSDVWSFGVLLWEIVS 94
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 35.4 bits (80), Expect = 0.16 Identities = 15/34 (44%), Positives = 23/34 (67%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 GT YM+PE Y+ K DV+SFG++L E+++ Sbjct: 168 GTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMT 201
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 35.4 bits (80), Expect = 0.16 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 1/106 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + +PE + G ++KSDV+SFG+LL+EI++ G+ + + + L +++ C Sbjct: 400 WTAPEAINFGSSTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENC 459 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLN 343 E L N + C + ++RPT + ++L+ Sbjct: 460 PEEL----------------YNIMMRCWKNRPEERPTFEYIQSVLD 489
>EPHB6_MOUSE (O08644) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) (MEP) Length = 1014 Score = 35.4 bits (80), Expect = 0.16 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQL 499 + +PE + G Y+ SDV+SFG+L+ E++S G+R ++ LN + ++L Sbjct: 820 WAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMNEQEVLNAIEQEFRL 873
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 35.4 bits (80), Expect = 0.16 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +MSPE G+++ SDV+SFGV+L EI Sbjct: 1174 WMSPESLKDGVFTTNSDVWSFGVVLWEI 1201
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/28 (57%), Positives = 21/28 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +M+PE GI+S SDV+SFGV+L EI Sbjct: 1218 WMAPESLKDGIFSTASDVWSFGVVLWEI 1245
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 35.4 bits (80), Expect = 0.16 Identities = 14/30 (46%), Positives = 24/30 (80%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE A+ +S+KSDV+SFG+LL E+++ Sbjct: 412 WTAPEAANYSKFSIKSDVWSFGILLTELVT 441
>DSOR1_DROME (Q24324) Dual specificity mitogen-activated protein kinase kinase| dSOR1 (EC 2.7.12.2) (Downstream of RAF) (MAPKK) Length = 396 Score = 35.4 bits (80), Expect = 0.16 Identities = 17/35 (48%), Positives = 23/35 (65%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 GT YMSPE YSV+SD++S G+ L+E+ G Sbjct: 244 GTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIG 278
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+ E + +Y+ KSDV+SFGVLL EI+S Sbjct: 1019 WMAIESLNYSVYTTKSDVWSFGVLLWEIVS 1048
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+ E + +Y+ KSDV+SFGVLL EI+S Sbjct: 1017 WMAIESLNYSVYTTKSDVWSFGVLLWEIVS 1046
>KCCS_MALDO (Q07250) Calcium/calmodulin-dependent serine/threonine-protein| kinase (EC 2.7.11.17) Length = 415 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/35 (45%), Positives = 25/35 (71%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 G+ Y+SPE SQG + KSD+++ GV+L ++SG Sbjct: 212 GSIDYVSPEALSQGQVTSKSDMWALGVILYILLSG 246
>FGR_HUMAN (P09769) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 529 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/33 (48%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+I+ R Sbjct: 424 WTAPEAALFGRFTIKSDVWSFGILLTELITKGR 456
>STK25_MOUSE (Q9Z2W1) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK-RNSSFH 544 GT +M+PE Q Y K+D++S G+ +E+ G+ NS H Sbjct: 177 GTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLH 219
>STK25_HUMAN (O00506) Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile| 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase) Length = 426 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK-RNSSFH 544 GT +M+PE Q Y K+D++S G+ +E+ G+ NS H Sbjct: 177 GTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLH 219
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 35.0 bits (79), Expect = 0.21 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +MSPE G+++ SDV+SFGV+L EI Sbjct: 451 WMSPESLKDGVFTTHSDVWSFGVVLWEI 478
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+ +SDV+SFGVLL EI S Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEIFS 1109
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 35.0 bits (79), Expect = 0.21 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +MSPE G+++ SDV+SFGV+L EI Sbjct: 1179 WMSPESLKDGVFTTHSDVWSFGVVLWEI 1206
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/49 (34%), Positives = 30/49 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLN 523 GT GYM+PE + Y+ D + G L+ E+I+G +S F ++++ +N Sbjct: 347 GTVGYMAPEIINHEKYTFSPDWWGLGCLIYEMIAG--HSPFRKYKEKVN 393
>EPHB6_RAT (P0C0K7) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) Length = 1013 Score = 35.0 bits (79), Expect = 0.21 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 1/54 (1%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQL 499 + +PE + G Y+ SDV+SFG+L+ E++S G+R ++ LN + ++L Sbjct: 819 WAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMSDQEVLNAIEQEFRL 872
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M PE +GI++ K+D +SFGVLL EI S Sbjct: 1295 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFS 1324
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+ +SDV+SFGVLL EI S Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEIFS 1109
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+ +SDV+SFGVLL EI S Sbjct: 1080 WMAPESIFDKVYTTQSDVWSFGVLLWEIFS 1109
>PKNB_LACLA (Q9CEF5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 627 Score = 35.0 bits (79), Expect = 0.21 Identities = 13/36 (36%), Positives = 26/36 (72%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 G+ Y+SPE A +V+SD+++ G++L E+++G+ Sbjct: 174 GSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQ 209
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 35.0 bits (79), Expect = 0.21 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 1/105 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + SPE S YS KSDV+SFGVL+ E+ S GK + + + + ++L++ Sbjct: 524 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLA 583 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 H + + C +E +DRP S ++ L Sbjct: 584 ----------STHVYQIMNH------CWKERPEDRPAFSRLLRQL 612
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M PE +GI++ K+D +SFGVLL EI S Sbjct: 1299 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFS 1328
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 35.0 bits (79), Expect = 0.21 Identities = 15/33 (45%), Positives = 25/33 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+++ R Sbjct: 430 WTAPEAALFGKFTIKSDVWSFGILLTELVTKGR 462
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 35.0 bits (79), Expect = 0.21 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +MSPE G+++ SDV+SFGV+L EI Sbjct: 1180 WMSPESLKDGVFTTHSDVWSFGVVLWEI 1207
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT Y+SPE A +SDV+S G +L EI++G+ Sbjct: 177 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEILTGE 212
>PKN5_MYXXA (P54737) Serine/threonine-protein kinase pkn5 (EC 2.7.11.1)| Length = 380 Score = 35.0 bits (79), Expect = 0.21 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GTY YM+PE ++D++S GV+L E++SG+ Sbjct: 283 GTYRYMAPEQILGEPLDGRADLYSLGVILYELLSGR 318
>IKKB_RAT (Q9QY78) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 22/37 (59%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y++PE Q Y+V D +SFG L E I+G R Sbjct: 184 GTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFR 220
>IKKB_MOUSE (O88351) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 22/37 (59%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y++PE Q Y+V D +SFG L E I+G R Sbjct: 184 GTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFR 220
>IKKB_HUMAN (O14920) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 756 Score = 35.0 bits (79), Expect = 0.21 Identities = 17/37 (45%), Positives = 22/37 (59%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y++PE Q Y+V D +SFG L E I+G R Sbjct: 184 GTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFR 220
>Y31E_CAEEL (Q8MYQ1) Putative serine/threonine-protein kinase F31E3.2 (EC| 2.7.11.1) Length = 441 Score = 34.7 bits (78), Expect = 0.27 Identities = 18/35 (51%), Positives = 23/35 (65%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISG 565 GT YMSP+ AS G YS D +S GVLL +++G Sbjct: 289 GTLQYMSPDVASGGTYSHYVDWWSLGVLLHILLTG 323
>MKK2_YEAST (P32491) MAP kinase kinase MKK2/SSP33 (EC 2.7.12.2)| Length = 506 Score = 34.7 bits (78), Expect = 0.27 Identities = 17/36 (47%), Positives = 22/36 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YM+PE YSV DV+S G+ LLE+ G+ Sbjct: 377 GTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGR 412
>CSF1R_FELCA (P13369) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 980 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+V+SDV+S+G+LL EI S Sbjct: 819 WMAPESIFDCVYTVQSDVWSYGILLWEIFS 848
>MST4_MOUSE (Q99JT2) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 34.7 bits (78), Expect = 0.27 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK-RNSSFH 544 GT +M+PE Q Y K+D++S G+ +E+ G+ NS H Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMH 223
>MST4_HUMAN (Q9P289) Serine/threonine-protein kinase MST4 (EC 2.7.11.1)| (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase) Length = 416 Score = 34.7 bits (78), Expect = 0.27 Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK-RNSSFH 544 GT +M+PE Q Y K+D++S G+ +E+ G+ NS H Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMH 223
>CSF1R_HUMAN (P07333) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) (CD115 antigen) Length = 972 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+V+SDV+S+G+LL EI S Sbjct: 821 WMAPESIFDCVYTVQSDVWSYGILLWEIFS 850
>BTK_HUMAN (Q06187) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) Length = 658 Score = 34.7 bits (78), Expect = 0.27 Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 5/110 (4%) Frame = -3 Query: 648 PEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRCLEL 472 PE +S KSD+++FGVL+ EI S GK +E F N S + L L Sbjct: 565 PEVLMYSKFSSKSDIWAFGVLMWEIYSLGKM-----PYERFTN----SETAEHIAQGLRL 615 Query: 471 LEASVANEVHAAEARRYVNTALMCVQEHADDRPT----MSNVITMLNSDS 334 +A+E + C E AD+RPT +SN++ +++ +S Sbjct: 616 YRPHLASE-------KVYTIMYSCWHEKADERPTFKILLSNILDVMDEES 658
>E2AK3_HUMAN (Q9NZJ5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK) Length = 1115 Score = 34.7 bits (78), Expect = 0.27 Identities = 16/33 (48%), Positives = 21/33 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEII 571 GT YMSPE YS K D+FS G++L E++ Sbjct: 985 GTKLYMSPEQIHGNSYSHKVDIFSLGLILFELL 1017
>TYK2_MOUSE (Q9R117) Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)| Length = 1180 Score = 34.7 bits (78), Expect = 0.27 Identities = 28/106 (26%), Positives = 47/106 (44%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEGGRCL 478 + +PE + + SDV+SFGV L E+++ +S+ H F L+G++ R Sbjct: 1060 WYAPECLKECKFYYASDVWSFGVTLYELLT-YCDSNQSPHTKFTELIGHTQGQMTVLRLT 1118 Query: 477 ELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNS 340 ELLE + C + A RPT N++ +L + Sbjct: 1119 ELLERGERLPRPDRCPCEIYHLMKNCWETEASFRPTFQNLVPILQT 1164
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +M+PE GI+S SDVFS+GV+L E+ Sbjct: 1205 WMAPESLKDGIFSSSSDVFSYGVVLWEM 1232
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEI 574 +MSPE G+++ SDV+SFGV+L EI Sbjct: 1178 WMSPESLKDGVFTTYSDVWSFGVVLWEI 1205
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 34.7 bits (78), Expect = 0.27 Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRC 481 + SPE S YS KSDV+SFGVL+ E+ S GK + + + + ++L++ Sbjct: 529 WASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYK---- 584 Query: 480 LELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 + + + +N C +E +DRP S +++ L Sbjct: 585 ---------PRLASCHVYQIMN---HCWKEKPEDRPPFSQLLSQL 617
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+V+SDV+S+G+LL EI S Sbjct: 819 WMAPESIFDCVYTVQSDVWSYGILLWEIFS 848
>KFMS_FSVMD (P00545) Tyrosine-protein kinase transforming protein fms (EC| 2.7.10.1) Length = 978 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+V+SDV+S+G+LL EI S Sbjct: 853 WMAPESIFDCVYTVQSDVWSYGILLWEIFS 882
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT Y+SPE A +SDV+S G +L E+++G+ Sbjct: 178 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGE 213
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT Y+SPE A +SDV+S G +L E+++G+ Sbjct: 178 GTAQYLSPEQARGDSVDARSDVYSLGCVLYEVLTGE 213
>JAK3_RAT (Q63272) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1100 Score = 34.7 bits (78), Expect = 0.27 Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 10/116 (8%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEGGRCL 478 + +PE S I+S +SDV+SFGV+L E+ + + S +FL ++G EG Sbjct: 989 WYAPESLSDNIFSRQSDVWSFGVVLYELFT-YSDKSCSPSTEFLRMIGPE---REGSPLC 1044 Query: 477 ELLEASVANEVHAAEARRYVNTAL----------MCVQEHADDRPTMSNVITMLNS 340 LLE AE RR + +C + DRP + L++ Sbjct: 1045 HLLEL-------LAEGRRLPPPSTCPTEVQELMQLCWSPNPQDRPAFDTLSPQLDA 1093
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 34.7 bits (78), Expect = 0.27 Identities = 15/51 (29%), Positives = 31/51 (60%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLL 517 GT YM+PE ++ +S +D +S+GVL+ E+++G + + +N++ Sbjct: 235 GTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMI 285
>E2AK1_MOUSE (Q9Z2R9) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor Length = 619 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/32 (50%), Positives = 20/32 (62%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEI 574 GT Y SPE Y KSD++S GV+LLE+ Sbjct: 489 GTCLYASPEQLEGSQYDAKSDMYSLGVILLEL 520
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 34.3 bits (77), Expect = 0.35 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE A+ ++S KSDV+SFG+LL E+ + Sbjct: 396 WTAPEAANYRVFSQKSDVWSFGILLYEVFT 425
>ROR2_MOUSE (Q9Z138) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2) Length = 944 Score = 34.3 bits (77), Expect = 0.35 Identities = 14/30 (46%), Positives = 22/30 (73%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +MSPE G +S+ SD++S+GV+L E+ S Sbjct: 658 WMSPEAVMYGKFSIDSDIWSYGVVLWEVFS 687
>NEK7_MOUSE (Q9ES74) Serine/threonine-protein kinase Nek7 (EC 2.7.11.1)| (NimA-related protein kinase 7) Length = 302 Score = 34.3 bits (77), Expect = 0.35 Identities = 32/107 (29%), Positives = 54/107 (50%), Gaps = 3/107 (2%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 GT YMSPE + Y+ KSD++S G LL E+ + S F + D +NL YS Sbjct: 198 GTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA--LQSPF--YGDKMNL--YS------ 245 Query: 489 GRCLELLEAS---VANEVHAAEARRYVNTALMCVQEHADDRPTMSNV 358 C ++ + + ++ ++ E R+ VN +C+ + RP ++ V Sbjct: 246 -LCKKIEQCDYPPLPSDHYSEELRQLVN---ICINPDPEKRPDIAYV 288
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 34.3 bits (77), Expect = 0.35 Identities = 24/108 (22%), Positives = 40/108 (37%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEG 490 G YM+PE S KSDV+S+G++L E+++ + +L Y Sbjct: 1467 GCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYE------ 1520 Query: 489 GRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 S + + ++ C + D RPT +I L Sbjct: 1521 ---------SYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHL 1559
>VGFR2_RAT (O08775) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) Length = 1343 Score = 34.3 bits (77), Expect = 0.35 Identities = 30/106 (28%), Positives = 42/106 (39%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEGGRCL 478 +M+PE IY+++S V+SFGVLL EI S L Y + C Sbjct: 1067 WMAPETIFDRIYTIQSGVWSFGVLLWEIFS-------------LGASPYPGVKIDEKFCR 1113 Query: 477 ELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITMLNS 340 L E + Y T L C E + RP S ++ L + Sbjct: 1114 RLKEGTRMRAPDYTTPEMY-QTMLDCWHEDPNQRPAFSELVEHLGN 1158
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/30 (53%), Positives = 21/30 (70%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE G +S KSDV+SFGVLL E+ S Sbjct: 388 WTAPEALKNGRFSSKSDVWSFGVLLWEVFS 417
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 435 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 467
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>MP2K5_RAT (Q62862) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YM+PE S Y + SDV+S G+ +E+ G+ Sbjct: 318 GTNAYMAPERISGEQYGIHSDVWSLGISFMELALGR 353
>MP2K5_MOUSE (Q9WVS7) Dual specificity mitogen-activated protein kinase kinase 5| (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5) Length = 448 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT YM+PE S Y + SDV+S G+ +E+ G+ Sbjct: 318 GTNAYMAPERISGEQYGIHSDVWSLGISFMELALGR 353
>BTK_MOUSE (P35991) Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton's| tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) Length = 658 Score = 34.3 bits (77), Expect = 0.35 Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 5/110 (4%) Frame = -3 Query: 648 PEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLLGYSWQLWEGGRCLEL 472 PE +S KSD+++FGVL+ EI S GK +E F N S + L L Sbjct: 565 PEVLMYSKFSSKSDIWAFGVLMWEIYSLGKM-----PYERFTN----SETAEHIAQGLRL 615 Query: 471 LEASVANEVHAAEARRYVNTALMCVQEHADDRPT----MSNVITMLNSDS 334 +A+E R C E AD+RP+ +SN++ +++ +S Sbjct: 616 YRPHLASE-------RVYTIMYSCWHEKADERPSFKILLSNILDVMDEES 658
>PK1_STRTO (Q9KIG4) Serine/threonine-protein kinase PK-1 (EC 2.7.11.1)| (stoPK-1) Length = 641 Score = 34.3 bits (77), Expect = 0.35 Identities = 13/37 (35%), Positives = 24/37 (64%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y++PE G + DV++ G+LL E+++G++ Sbjct: 178 GTVSYLAPEQIEHGTADPRVDVYACGILLYEMLTGEK 214
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 424 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 456
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>NRKA_TRYBB (Q08942) Putative serine/threonine-protein kinase A (EC 2.7.11.1)| Length = 431 Score = 34.3 bits (77), Expect = 0.35 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y++PE + Y+ K+DV+S GVLL EI+ K+ Sbjct: 186 GTPYYLAPELWNNKRYNKKADVWSLGVLLYEIMGMKK 222
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/30 (53%), Positives = 21/30 (70%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE G +S KSDV+SFGVLL E+ S Sbjct: 350 WTAPEALKNGRFSSKSDVWSFGVLLWEVFS 379
>E2AK1_RAT (Q63185) Eukaryotic translation initiation factor 2-alpha kinase 1| (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor) (Heme-controlled repressor) (HCR) (Hemin-sensitive initiation factor 2- Length = 620 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/32 (50%), Positives = 20/32 (62%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEI 574 GT Y SPE Y KSD++S GV+LLE+ Sbjct: 490 GTCLYASPEQLEGSEYDAKSDMYSLGVILLEL 521
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 34.3 bits (77), Expect = 0.35 Identities = 17/37 (45%), Positives = 24/37 (64%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y++PE A + SDV+S GV+ E++SGKR Sbjct: 179 GTAQYIAPEQALGHDATPASDVYSLGVIGYEVVSGKR 215
>GCY_STRPU (P16065) Speract receptor precursor (Guanylate cyclase) (EC 4.6.1.2)| Length = 1125 Score = 34.3 bits (77), Expect = 0.35 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 1/93 (1%) Frame = -3 Query: 621 SVKSDVFSFGVLLLEIISGKRNSSFHEHE-DFLNLLGYSWQLWEGGRCLELLEASVANEV 445 S + D++SF ++L E+ S R FHE+E D +++G + G + N V Sbjct: 755 SPQGDIYSFAIILTELYS--RQEPFHENEMDLADIIGRV----KSGEVPPY--RPILNAV 806 Query: 444 HAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 +AA ++ C E DRP + V TML Sbjct: 807 NAAAPDCVLSAIRACWPEDPADRPNIMAVRTML 839
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 427 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 459
>E2AK3_MOUSE (Q9Z2B5) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1114 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/33 (48%), Positives = 21/33 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEII 571 GT YMSPE YS K D+FS G++L E++ Sbjct: 984 GTKLYMSPEQIHGNNYSHKVDIFSLGLILFELL 1016
>CSF1R_RAT (Q00495) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 978 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+V+SDV+S+G+LL EI S Sbjct: 819 WMAPESILYCVYTVQSDVWSYGILLWEIFS 848
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 430 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 462
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 430 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 462
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 426 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 458
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/33 (45%), Positives = 24/33 (72%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 + +PE A G +++KSDV+SFG+LL E+ + R Sbjct: 426 WTAPEAALYGRFTIKSDVWSFGILLTELTTKGR 458
>E2AK3_RAT (Q9Z1Z1) Eukaryotic translation initiation factor 2-alpha kinase 3| precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) Length = 1108 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/33 (48%), Positives = 21/33 (63%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEII 571 GT YMSPE YS K D+FS G++L E++ Sbjct: 978 GTKLYMSPEQIHGNNYSHKVDIFSLGLILFELL 1010
>TNK1_HUMAN (Q13470) Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2)| (CD38 negative kinase 1) Length = 666 Score = 34.3 bits (77), Expect = 0.35 Identities = 29/106 (27%), Positives = 41/106 (38%) Frame = -3 Query: 663 YGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKRNSSFHEHEDFLNLLGYSWQLWEGGR 484 Y + +PE G +S SDV+ FGV L E+ SG W Sbjct: 287 YAWCAPESLRHGAFSSASDVWMFGVTLWEMFSGGEE---------------PWAGVPPYL 331 Query: 483 CLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 L+ LE +R + AL C H DRP+ S++ +L Sbjct: 332 ILQRLEDRARLPRPPLCSRALYSLALRCWAPHPADRPSFSHLEGLL 377
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor| (EC 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/30 (50%), Positives = 21/30 (70%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M+PE +Y+ SDV+SFG+LL EI S Sbjct: 861 WMAPESIFDNLYTTLSDVWSFGILLWEIFS 890
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/34 (44%), Positives = 24/34 (70%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 G+ +M+PE Y+ K+DVFS+G++L EII+ Sbjct: 218 GSPFWMAPEVLRDEPYNEKADVFSYGIILCEIIA 251
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT +M+PE S K D++SFGV+L E+++G+ Sbjct: 305 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE 340
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT +M+PE S K D++SFGV+L E+++G+ Sbjct: 305 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE 340
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 33.9 bits (76), Expect = 0.46 Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 1/48 (2%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-GKRNSSFHEHEDFLNLL 517 +M PE +G+++ K+D +SFGVLL EI S G H +++ L+ + Sbjct: 685 WMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFI 732
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 33.9 bits (76), Expect = 0.46 Identities = 13/30 (43%), Positives = 24/30 (80%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE G++++K+DV+SFGVLL+ I++ Sbjct: 394 WTAPEAIHFGVFTIKADVWSFGVLLMVIVT 423
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 33.9 bits (76), Expect = 0.46 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 7/111 (6%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS-------GKRNSSFHEHEDFLNLLGYSWQL 499 + +PE A +++KSDV+SFGVL+ EI++ G N E D GY Sbjct: 228 WTAPEAALYNRFTIKSDVWSFGVLISEIVTHGRMPYPGMTNRQVLEAVD----RGYRMPC 283 Query: 498 WEGGRCLELLEASVANEVHAAEARRYVNTALMCVQEHADDRPTMSNVITML 346 EG C + L L C + DDRPT ++ +L Sbjct: 284 PEG--CPDPL----------------YKIMLSCWKHEPDDRPTFESLKNLL 316
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 33.9 bits (76), Expect = 0.46 Identities = 17/37 (45%), Positives = 24/37 (64%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGKR 559 GT Y+SPE A + SDV+S GV+ E++SG+R Sbjct: 186 GTAQYVSPEQAQGHQVTPASDVYSLGVVGYEMLSGRR 222
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT GYM+PE Y+ D ++ G LL E+I+G+ Sbjct: 347 GTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQ 382
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/36 (41%), Positives = 22/36 (61%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT GYM+PE Y+ D ++ G LL E+I+G+ Sbjct: 347 GTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQ 382
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 + +PE A +++KSDV+SFGV+L EII+ Sbjct: 401 WTAPEAAMYNRFTIKSDVWSFGVVLYEIIT 430
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 33.9 bits (76), Expect = 0.46 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +M PE +GI++ K+D +SFGVLL EI S Sbjct: 689 WMPPEAFLEGIFTSKTDSWSFGVLLWEIFS 718
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT +M+PE S K D++SFGV+L E+++G+ Sbjct: 272 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE 307
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 33.9 bits (76), Expect = 0.46 Identities = 15/36 (41%), Positives = 24/36 (66%) Frame = -3 Query: 669 GTYGYMSPEYASQGIYSVKSDVFSFGVLLLEIISGK 562 GT +M+PE S K D++SFGV+L E+++G+ Sbjct: 315 GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGE 350
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 33.9 bits (76), Expect = 0.46 Identities = 14/30 (46%), Positives = 23/30 (76%) Frame = -3 Query: 657 YMSPEYASQGIYSVKSDVFSFGVLLLEIIS 568 +MSPE G+++ +SDV++FGVL EI++ Sbjct: 2393 WMSPESLVDGLFTTQSDVWAFGVLCWEILT 2422 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,019,324 Number of Sequences: 219361 Number of extensions: 1757254 Number of successful extensions: 4965 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 4764 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4928 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6541540170 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
