ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal12f06 |
|---|---|
| Clone Library Name | barley_pub |
>PHOT2_ARATH (P93025) Phototropin-2 (EC 2.7.11.1) (Defective in chloroplast| avoidance protein 1) (Non phototropic hypocotyl 1-like protein 1) (NPH1-like 1) (AtKin7) Length = 915 Score = 192 bits (487), Expect = 1e-48 Identities = 92/120 (76%), Positives = 101/120 (84%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +ITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNR+KTF NILHKDLTFPSSIPVSL + Sbjct: 775 IITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRQKTFANILHKDLTFPSSIPVSLVGR 834 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 QLI+ LL RDPSSR+GS GAN+IK+H FF I WPLIR MSPP LD PL +I K+ K Sbjct: 835 QLINTLLNRDPSSRLGSKGGANEIKQHAFFRGINWPLIRGMSPPPLDAPLSIIEKDPNAK 894
>PHOT1_ARATH (O48963) Phototropin-1 (EC 2.7.11.1) (Non-phototropic hypocotyl| protein 1) (Root phototropism protein 1) Length = 996 Score = 167 bits (422), Expect = 3e-41 Identities = 78/125 (62%), Positives = 95/125 (76%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I+GAGHTSA+DWWALGIL+YEMLYG TPFRGK R+KTF N+L KDL FP+SIP SL+ K Sbjct: 863 IISGAGHTSAVDWWALGILMYEMLYGYTPFRGKTRQKTFTNVLQKDLKFPASIPASLQVK 922 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 QLI LLQRDP R+G GAN++K+H FF+ I W LIRC +PPEL+ P+ E+ K Sbjct: 923 QLIFRLLQRDPKKRLGCFEGANEVKQHSFFKGINWALIRCTNPPELETPIFSGEAENGEK 982 Query: 296 VKPEE 282 V E Sbjct: 983 VVDPE 987
>G11A_ORYSA (P47997) Protein kinase G11A (EC 2.7.11.1)| Length = 589 Score = 134 bits (336), Expect = 3e-31 Identities = 57/119 (47%), Positives = 79/119 (66%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G GH SA+DWW GI LYE+L+G+TPF+G + T +N++ + L FP VS A+ Sbjct: 444 IIKGEGHGSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVIGQPLRFPEYPVVSFSAR 503 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 LI GLL ++P R+G GA +IK+HPFFE + W LIRC SPPE+ P+++ QP Sbjct: 504 DLIRGLLVKEPQQRLGCKRGATEIKQHPFFEGVNWALIRCASPPEVPRPVEIERPPKQP 562
>KPK1_PHAVU (P15792) Protein kinase PVPK-1 (EC 2.7.11.1)| Length = 609 Score = 130 bits (327), Expect = 3e-30 Identities = 61/132 (46%), Positives = 84/132 (63%), Gaps = 3/132 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G GH SA+DWW GI LYE+L+GRTPF+G + T +N++ + L FP S VS A+ Sbjct: 476 IIKGEGHGSAVDWWTFGIFLYELLFGRTPFKGSANRATLFNVIGQPLRFPESPTVSFAAR 535 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 LI GLL ++P R+ GA +IK+HPFF+++ W LIRC +PPE VP ++I K Sbjct: 536 DLIRGLLVKEPQHRLAYRRGATEIKQHPFFQNVNWALIRCATPPE--VPRQVINLPQTEK 593 Query: 296 ---VKPEEGVID 270 VKP +D Sbjct: 594 DLGVKPSGNYLD 605
>KAD5_SCHPO (Q09831) Probable serine/threonine-protein kinase C4G8.05 (EC| 2.7.11.1) Length = 566 Score = 127 bits (320), Expect = 2e-29 Identities = 60/107 (56%), Positives = 73/107 (68%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP---SSIPVSL 486 VI G GHTSA+DWW LGIL YEMLY TPF+GKNR TF NILHKD+ FP + +S Sbjct: 393 VIKGCGHTSAVDWWTLGILFYEMLYATTPFKGKNRNMTFSNILHKDVIFPEYADAPSISS 452 Query: 485 EAKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 K LI LL +D + R+GS GA D+K HPFF+++ W L+R PP Sbjct: 453 LCKNLIRKLLVKDENDRLGSQAGAADVKLHPFFKNVQWALLRHTEPP 499
>NRC2_NEUCR (O42626) Serine/threonine-protein kinase nrc-2 (EC 2.7.11.1)| (Nonrepressible conidiation protein 2) Length = 623 Score = 127 bits (319), Expect = 3e-29 Identities = 61/107 (57%), Positives = 74/107 (69%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP---SSIPVSL 486 VI G+GHTSA+DWW LGIL+YEMLYG TPF+GKNR TF NIL +D+ FP + +S Sbjct: 440 VIKGSGHTSAVDWWTLGILIYEMLYGTTPFKGKNRNATFANILREDIPFPDHAGAPQISN 499 Query: 485 EAKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 K LI LL +D + R+G+ GA+DIK HPFF W LIR M PP Sbjct: 500 LCKSLIRKLLIKDENRRLGARAGASDIKTHPFFRTTQWALIRHMKPP 546
>KPK7_ARATH (Q05999) Putative serine/threonine-protein kinase PK7 (EC 2.7.11.1)| Length = 578 Score = 127 bits (318), Expect = 4e-29 Identities = 54/111 (48%), Positives = 75/111 (67%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G GH SA+DWW GI LYE+L+G TPFRG + + T +N++ + L FP VS A+ Sbjct: 427 IIKGEGHGSAVDWWTFGIFLYELLFGITPFRGGDNRATLFNVVGQPLRFPEHPNVSFAAR 486 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLK 324 LI GLL ++P R+ GA +IK+HPFF+ + W LIRC SPP++ P+K Sbjct: 487 DLIRGLLVKEPQHRLAYRRGATEIKQHPFFQSVNWALIRCTSPPQIPQPVK 537
>KIN82_YEAST (P25341) Probable serine/threonine-protein kinase KIN82 (EC| 2.7.11.1) Length = 720 Score = 123 bits (309), Expect = 4e-28 Identities = 56/104 (53%), Positives = 71/104 (68%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI G GHT+A+DWW LGIL+YEML+G TPF+G N +TF NIL KD+ FP VS K Sbjct: 513 VIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCK 572 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 LI LL ++ + R+GS +GA DIK HPFF+ + W +R PP Sbjct: 573 DLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQDPP 616
>KN8R_YEAST (P53739) Probable serine/threonine-protein kinase YNR047W (EC| 2.7.11.1) Length = 893 Score = 122 bits (305), Expect = 1e-27 Identities = 54/108 (50%), Positives = 75/108 (69%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI G GHT+A+DWW LGIL+YEML+G TPF+G N +TF NIL +++FP++ +S K Sbjct: 688 VIRGNGHTAAVDWWTLGILIYEMLFGFTPFKGDNTNETFTNILKNEVSFPNNNEISRTCK 747 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDV 333 LI LL ++ S R+G GA D+K+HPFF+ + W L+R PP + V Sbjct: 748 DLIKKLLTKNESKRLGCKMGAADVKKHPFFKKVQWSLLRNQEPPLIPV 795
>GAD8_SCHPO (Q9P7J8) Serine/threonine-protein kinase gad8 (EC 2.7.11.1)| Length = 569 Score = 98.6 bits (244), Expect = 1e-20 Identities = 56/131 (42%), Positives = 72/131 (54%), Gaps = 1/131 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G G+T +DWW LG+LLYEM+ G PF +N + + IL L FP +I +AK Sbjct: 399 LLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNI--DEKAK 456 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 L+ GLL R P R+GS GA +IK HPFF+DI W KL K+ QP Sbjct: 457 DLLSGLLTRAPEKRLGSG-GAQEIKNHPFFDDIDWK--------------KLCAKKIQPP 501 Query: 296 VKPE-EGVIDT 267 KP E IDT Sbjct: 502 FKPSVESAIDT 512
>YPK2_YEAST (P18961) Serine/threonine-protein kinase YPK2/YKR2 (EC 2.7.11.1)| Length = 677 Score = 94.4 bits (233), Expect = 3e-19 Identities = 53/137 (38%), Positives = 76/137 (55%), Gaps = 6/137 (4%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G G+T +DWW LGILLYEM+ G P+ +N + IL + L FP + AK Sbjct: 513 ILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPA--AK 570 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWP--LIRCMSPPELDVPLKLIG---- 315 L+ GLL RDPS R+G N G ++I+ HPFF+DI W L++ PP + I Sbjct: 571 DLLIGLLSRDPSRRLGVN-GTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANF 629 Query: 314 KESQPKVKPEEGVIDTF 264 + K KP + V+D + Sbjct: 630 DQEFTKEKPIDSVVDEY 646
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 92.0 bits (227), Expect = 1e-18 Identities = 46/106 (43%), Positives = 66/106 (62%), Gaps = 2/106 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G G+T A+DWW LG+LLYEML G P+ ++ K + IL + L FP +AK Sbjct: 516 LLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGF--DRDAK 573 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWP--LIRCMSPP 345 L+ GLL RDP+ R+G N GA++I+ HPFF + W L++ PP Sbjct: 574 DLLIGLLSRDPTRRLGYN-GADEIRNHPFFSQLSWKRLLMKGYIPP 618
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/127 (39%), Positives = 69/127 (54%), Gaps = 1/127 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GHT + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 230 VVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFL--SAEAQ 287 Query: 476 QLIHGLLQRDPSSRIGSNT-GANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P +R+G+ G +IK HPFF I W KL KE +P Sbjct: 288 SLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWN--------------KLYRKEIKP 333 Query: 299 KVKPEEG 279 KP G Sbjct: 334 PFKPAVG 340 Score = 38.1 bits (87), Expect = 0.023 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 6/95 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHK------DLTFPSSIP 495 V+ G+ +A D W+LGILLY ML G TPF T IL + L+ + Sbjct: 582 VLKRQGYDAACDVWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGNWDS 640 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPF 390 +S AK ++ +L DP R+ A + +HP+ Sbjct: 641 ISDAAKDVVSKMLHVDPQQRL----TAVQVLKHPW 671
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 90.5 bits (223), Expect = 4e-18 Identities = 50/130 (38%), Positives = 72/130 (55%), Gaps = 1/130 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GH+ + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 251 VVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFL--SAEAQ 308 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P++R+GS GA +IK HPF+ I W KL +E +P Sbjct: 309 SLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWN--------------KLYRREIKP 354 Query: 299 KVKPEEGVID 270 KP G D Sbjct: 355 PFKPAVGQPD 364 Score = 37.7 bits (86), Expect = 0.030 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 6/95 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSI------P 495 V+ G+ D W+LG+LLY ML G TPF T IL + S+ Sbjct: 602 VLKRQGYDEGCDIWSLGVLLYTMLAGCTPF-ANGPSDTPEEILTRIGGGKFSVNGGNWDT 660 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPF 390 +S AK L+ +L DP R+ A + +HP+ Sbjct: 661 ISDVAKDLVSKMLHVDPHQRL----TAKQVLQHPW 691
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 90.1 bits (222), Expect = 5e-18 Identities = 46/107 (42%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ +GH A+DWW+LG L+Y+ML G PF G+NRKKT IL L P + + EA+ Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYL--TQEAR 321 Query: 476 QLIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDIYWP--LIRCMSPP 345 L+ LL+R+ +SR+G+ G A +++ HPFF I W L R + PP Sbjct: 322 DLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 90.1 bits (222), Expect = 5e-18 Identities = 46/107 (42%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ +GH A+DWW+LG L+Y+ML G PF G+NRKKT IL L P + + EA+ Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYL--TQEAR 321 Query: 476 QLIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDIYWP--LIRCMSPP 345 L+ LL+R+ +SR+G+ G A +++ HPFF I W L R + PP Sbjct: 322 DLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 90.1 bits (222), Expect = 5e-18 Identities = 46/107 (42%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ +GH A+DWW+LG L+Y+ML G PF G+NRKKT IL L P + + EA+ Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYL--TQEAR 321 Query: 476 QLIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDIYWP--LIRCMSPP 345 L+ LL+R+ +SR+G+ G A +++ HPFF I W L R + PP Sbjct: 322 DLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 90.1 bits (222), Expect = 5e-18 Identities = 46/107 (42%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ +GH A+DWW+LG L+Y+ML G PF G+NRKKT IL L P + + EA+ Sbjct: 264 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYL--TQEAR 321 Query: 476 QLIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDIYWP--LIRCMSPP 345 L+ LL+R+ +SR+G+ G A +++ HPFF I W L R + PP Sbjct: 322 DLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPP 368
>KS6AA_XENLA (P10665) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 733 Score = 88.2 bits (217), Expect = 2e-17 Identities = 47/107 (43%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GH+ + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 233 VVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFL--SNEAQ 290 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLI--RCMSPP 345 L+ L +R+P++R+GS GA +IK PFF I W + R MSPP Sbjct: 291 SLLRALFKRNPTNRLGSAMEGAEEIKRQPFFSTIDWNKLFRREMSPP 337 Score = 39.3 bits (90), Expect = 0.010 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 5/80 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFR---GKNRKKTFYNILHKDLTFPSS--IPV 492 V+ G+ D W+LGILLY ML G TPF G ++ I T V Sbjct: 583 VLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTLRGGNWNTV 642 Query: 491 SLEAKQLIHGLLQRDPSSRI 432 S AK L+ +L DP R+ Sbjct: 643 SAAAKDLVSRMLHVDPHKRL 662
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 87.4 bits (215), Expect = 3e-17 Identities = 49/129 (37%), Positives = 70/129 (54%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GH+ + DWW+ G+L++EML G PF+GK+R +T IL L P + S EA+ Sbjct: 244 VVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFL--SAEAQ 301 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 L+ L +R+P++R+GS G +IK H FF +I W KL +E QP Sbjct: 302 SLLRMLFKRNPANRLGSE-GVEEIKRHLFFANIDWD--------------KLYKREVQPP 346 Query: 296 VKPEEGVID 270 KP G D Sbjct: 347 FKPASGKPD 355 Score = 36.2 bits (82), Expect = 0.088 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 6/80 (7%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHK------DLTFPSSIP 495 V+ G+ +A D W+LG+L Y ML G TPF T IL + L+ + Sbjct: 593 VLMQQGYDAACDIWSLGVLFYTMLAGYTPF-ANGPNDTPEEILLRIGNGKFSLSGGNWDN 651 Query: 494 VSLEAKQLIHGLLQRDPSSR 435 +S AK L+ +L DP R Sbjct: 652 ISDGAKDLLSHMLHMDPHQR 671
>PK2_DICDI (P28178) Protein kinase 2 (EC 2.7.11.1)| Length = 479 Score = 87.4 bits (215), Expect = 3e-17 Identities = 43/95 (45%), Positives = 61/95 (64%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ G GH A+DWW+LG LLYEML G PF +N + IL+ +L P+ I S EAK Sbjct: 321 VLNGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYI--SPEAK 378 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 L+ GLL R+ R+G+ G ++K+HP+F++I W Sbjct: 379 SLLEGLLTREVDKRLGTK-GGGEVKQHPWFKNIDW 412
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 87.0 bits (214), Expect = 4e-17 Identities = 49/127 (38%), Positives = 68/127 (53%), Gaps = 1/127 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GHT + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 230 VVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFL--SGEAQ 287 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P +R+G+ G +IK HPFF I W L KE +P Sbjct: 288 SLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWN--------------TLYRKEIKP 333 Query: 299 KVKPEEG 279 KP G Sbjct: 334 PFKPAVG 340 Score = 38.1 bits (87), Expect = 0.023 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 6/95 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHK------DLTFPSSIP 495 V+ G+ +A D W+LGILLY ML G TPF T IL + L+ + Sbjct: 582 VLKRQGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGNWDS 640 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPF 390 +S AK ++ +L DP R+ A + +HP+ Sbjct: 641 ISDAAKDVVSKMLHVDPHQRL----TAMQVLKHPW 671
>KS6AB_XENLA (P10666) Ribosomal protein S6 kinase 2 beta (EC 2.7.11.1)| (Ribosomal protein S6 kinase II beta) (S6KII-beta) (P90-RSK) Length = 629 Score = 87.0 bits (214), Expect = 4e-17 Identities = 45/107 (42%), Positives = 66/107 (61%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GH+ DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 233 VVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFL--SNEAQ 290 Query: 476 QLIHGLLQRDPSSRIGSNT-GANDIKEHPFFEDIYWPLI--RCMSPP 345 L+ L +R+ ++R+GS GA ++K HPFF I W + R +SPP Sbjct: 291 SLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPP 337 Score = 35.4 bits (80), Expect = 0.15 Identities = 16/30 (53%), Positives = 19/30 (63%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF 567 V+ G+ D W+LGILLY ML G TPF Sbjct: 583 VLKRQGYDEGCDIWSLGILLYTMLAGYTPF 612
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 86.7 bits (213), Expect = 6e-17 Identities = 48/124 (38%), Positives = 69/124 (55%), Gaps = 1/124 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GHT + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 233 VVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFL--STEAQ 290 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P++R+GS GA +IK H F+ I W KL +E +P Sbjct: 291 SLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWN--------------KLYRREIKP 336 Query: 299 KVKP 288 KP Sbjct: 337 PFKP 340 Score = 40.0 bits (92), Expect = 0.006 Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHK------DLTFPSSIP 495 V+ G+ D W+LG+LLY ML G TPF T IL + L+ + Sbjct: 585 VLKRQGYDEGCDIWSLGVLLYTMLAGYTPF-ANGPSDTPEEILTRISSGKFTLSGGNWNT 643 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPF 390 VS AK L+ +L DP R+ A + +HP+ Sbjct: 644 VSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 674
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 86.3 bits (212), Expect = 7e-17 Identities = 44/107 (41%), Positives = 62/107 (57%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ GH A+DWW+LG L+Y+ML G PF +NRKKT I+ L P + + +A+ Sbjct: 240 ILVRTGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYL--TPDAR 297 Query: 476 QLIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDIYWP--LIRCMSPP 345 L L+R+P+ RIG G A D++ HPFF I W L R + PP Sbjct: 298 DLAKKFLKRNPTQRIGGGLGDAADVQRHPFFRHINWDDLLARRVDPP 344
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 86.3 bits (212), Expect = 7e-17 Identities = 48/127 (37%), Positives = 68/127 (53%), Gaps = 1/127 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GHT + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 239 VVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFL--SPEAQ 296 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P++R+G+ G +IK H FF I W KL +E P Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWN--------------KLYRREIHP 342 Query: 299 KVKPEEG 279 KP G Sbjct: 343 PFKPATG 349 Score = 39.3 bits (90), Expect = 0.010 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 6/101 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSI------P 495 V+ G+ +A D W+LG+LLY ML G TPF T IL + + S+ Sbjct: 589 VLKRQGYDAACDIWSLGVLLYTMLTGYTPF-ANGPDDTPEEILARIGSGKFSLSGGYWNS 647 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 VS AK L+ +L DP R+ A + HP+ ++W Sbjct: 648 VSDTAKDLVSKMLHVDPHQRL----TAALVLRHPWI--VHW 682
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 86.3 bits (212), Expect = 7e-17 Identities = 48/127 (37%), Positives = 68/127 (53%), Gaps = 1/127 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GHT + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 239 VVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFL--SPEAQ 296 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P++R+G+ G +IK H FF I W KL +E P Sbjct: 297 SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWN--------------KLYRREIHP 342 Query: 299 KVKPEEG 279 KP G Sbjct: 343 PFKPATG 349 Score = 39.3 bits (90), Expect = 0.010 Identities = 33/101 (32%), Positives = 48/101 (47%), Gaps = 6/101 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSI------P 495 V+ G+ +A D W+LG+LLY ML G TPF T IL + + S+ Sbjct: 589 VLKRQGYDAACDIWSLGVLLYTMLTGYTPF-ANGPDDTPEEILARIGSGKFSLSGGYWNS 647 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 VS AK L+ +L DP R+ A + HP+ ++W Sbjct: 648 VSDTAKDLVSKMLHVDPHQRL----TAALVLRHPWI--VHW 682
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 86.3 bits (212), Expect = 7e-17 Identities = 40/96 (41%), Positives = 59/96 (61%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ +GH A+DWW+LG L+Y+ML G PF +NRKKT I+ L P + + +A+ Sbjct: 240 ILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL--TPDAR 297 Query: 476 QLIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDIYW 372 L+ L+R+PS RIG G A D++ HPFF + W Sbjct: 298 DLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNW 333
>PKN2_HUMAN (Q16513) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 984 Score = 85.9 bits (211), Expect = 1e-16 Identities = 42/107 (39%), Positives = 68/107 (63%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+L+YEML G +PF G + ++ F +I++ ++ +P + S EA Sbjct: 828 VLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFL--STEAI 885 Query: 476 QLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++ LL+R+P R+G S A D+K+HPFF I W + + + PP Sbjct: 886 SIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPP 932
>PKN1_HUMAN (Q16512) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha) Length = 942 Score = 85.9 bits (211), Expect = 1e-16 Identities = 43/107 (40%), Positives = 68/107 (63%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+LLYEML G +PF G + ++ F +I++ ++ +P + S EA Sbjct: 786 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFL--SAEAI 843 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWP--LIRCMSPP 345 ++ LL+R+P R+GS+ A D+K+ PFF + W L R + PP Sbjct: 844 GIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPP 890
>PKN1_MOUSE (P70268) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) Length = 946 Score = 85.9 bits (211), Expect = 1e-16 Identities = 43/107 (40%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+LLYEML G +PF G + ++ F +I++ ++ +P + S EA Sbjct: 790 VLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFL--SAEAI 847 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWP--LIRCMSPP 345 ++ LL+R+P R+GS A D+K+ PFF + W L R + PP Sbjct: 848 GIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPP 894
>PCK1_SCHPO (P36582) Protein kinase C-like 1 (EC 2.7.11.13)| Length = 988 Score = 85.5 bits (210), Expect = 1e-16 Identities = 38/90 (42%), Positives = 60/90 (66%), Gaps = 1/90 (1%) Frame = -3 Query: 638 HTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGL 459 ++ +DWWA G+L+Y+ML G++PF+G++ ++ F IL + FP ++P +A L+ GL Sbjct: 841 YSKDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPA--DAVSLLRGL 898 Query: 458 LQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 L RDP+ R+GS AN++ HPFF I W Sbjct: 899 LTRDPNQRLGSGPKDANEVMAHPFFASIVW 928
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 85.5 bits (210), Expect = 1e-16 Identities = 47/124 (37%), Positives = 69/124 (55%), Gaps = 1/124 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GH+ + DWW+ G+L++EML G PF+GK+RK+T IL L P + S EA+ Sbjct: 233 VVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFL--STEAQ 290 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P++R+GS GA +IK H F+ I W KL +E +P Sbjct: 291 SLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWN--------------KLYRREIKP 336 Query: 299 KVKP 288 KP Sbjct: 337 PFKP 340 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHK------DLTFPSSIP 495 V+ G+ D W+LGILLY ML G TPF T IL + L+ + Sbjct: 585 VLKRQGYDEGCDIWSLGILLYTMLAGYTPF-ANGPSDTPEEILTRIGSGKFTLSGGNWNT 643 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPF 390 VS AK L+ +L DP R+ A + +HP+ Sbjct: 644 VSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 674
>KPC3_DROME (P13678) Protein kinase C (EC 2.7.11.13) (PKC) (dPKC98F)| Length = 634 Score = 84.3 bits (207), Expect = 3e-16 Identities = 37/98 (37%), Positives = 62/98 (63%), Gaps = 2/98 (2%) Frame = -3 Query: 632 SAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQ 453 +++DWWALG+L+YEM+ G+ PF N + F +I+H D+ +P + +S EA ++ G L Sbjct: 481 ASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYP--VWLSREAVSILKGFLT 538 Query: 452 RDPSSRIGSNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++P R+G N+I++HPFF + W + R + PP Sbjct: 539 KNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPP 576
>KPK19_ARATH (Q39030) Serine/threonine-protein kinase AtPK19 (EC 2.7.11.1)| (Ribosomal-protein S6 kinase homolog) Length = 471 Score = 84.3 bits (207), Expect = 3e-16 Identities = 49/124 (39%), Positives = 69/124 (55%), Gaps = 1/124 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G GH A DWW++GILLYEML G+ PF G ++ K I+ + P + S EA Sbjct: 308 IVRGKGHDKAADWWSVGILLYEMLTGKPPFLG-SKGKIQQKIVKDKIKLPQFL--SNEAH 364 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ GLLQ++P R+GS +GA +IK+H +F+ I W KL +E QP Sbjct: 365 ALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWK--------------KLEAREVQP 410 Query: 299 KVKP 288 KP Sbjct: 411 SFKP 414
>KPK1_ARATH (P42818) Serine/threonine-protein kinase AtPK1/AtPK6 (EC 2.7.11.1)| Length = 465 Score = 84.3 bits (207), Expect = 3e-16 Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G GH A DWW++GILLYEML G+ PF G ++ K I+ + P + S EA Sbjct: 302 IVRGKGHDKAADWWSVGILLYEMLTGKPPFLG-SKGKIQQKIVKDKIKLPQFL--SNEAH 358 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 ++ GLLQ++P R+GS +GA +IK+H +F+ I W KL +E P Sbjct: 359 AILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWK--------------KLEAREVMP 404 Query: 299 KVKPE 285 KPE Sbjct: 405 SFKPE 409
>SCK2_SCHPO (Q10364) Serine/threonine-protein kinase sck2 (EC 2.7.11.1)| Length = 646 Score = 84.3 bits (207), Expect = 3e-16 Identities = 47/130 (36%), Positives = 72/130 (55%), Gaps = 1/130 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ AG+ +D+W+LG+LLYEM G +PF N ++ + NI+ + FP + +S+EA+ Sbjct: 439 ILDEAGYDMMVDFWSLGVLLYEMTCGWSPFYADNTQQLYKNIVFGKVRFPRGL-LSVEAR 497 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 LI LL R+P R+G++ ++ +HPFF+ I W KL KE P Sbjct: 498 DLIKLLLNRNPKHRLGAHGDVEEVMKHPFFDGIDWK--------------KLAAKEISPP 543 Query: 296 VKP-EEGVID 270 KP EG ID Sbjct: 544 FKPIVEGEID 553
>AKT1_BOVIN (Q01314) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 84.0 bits (206), Expect = 4e-16 Identities = 41/98 (41%), Positives = 64/98 (65%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +++ FP ++ S EAK L+ GLL++ Sbjct: 329 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTL--SPEAKSLLSGLLKK 386 Query: 449 DPSSRIGSNT-GANDIKEHPFFEDIYWPLI--RCMSPP 345 DP R+G + A +I +H FF I W + + +SPP Sbjct: 387 DPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKKLSPP 424
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 84.0 bits (206), Expect = 4e-16 Identities = 38/96 (39%), Positives = 60/96 (62%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V++ + ++DWW+ G+L+YEML G TPF N KT+ NIL+ +L FP +A+ Sbjct: 254 VVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFF--HPDAQ 311 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ L+ RD S R+G+ G+ D+K HP+F ++ W Sbjct: 312 DLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIW 347
>PKN1_RAT (Q63433) Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein| kinase C-like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protease-activated kinase 1) (PAK-1) Length = 946 Score = 84.0 bits (206), Expect = 4e-16 Identities = 42/107 (39%), Positives = 66/107 (61%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+ LYEML G +PF G + ++ F +I++ ++ +P + S EA Sbjct: 790 VLTDTSYTRAVDWWGLGVFLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFL--SAEAI 847 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWP--LIRCMSPP 345 ++ LL+R+P R+GS A D+K+ PFF + W L R + PP Sbjct: 848 GIMRRLLRRNPERRLGSTERDAEDVKKQPFFRTLDWDALLARRLPPP 894
>AKT1_MOUSE (P31750) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto-oncogene) Length = 480 Score = 83.6 bits (205), Expect = 5e-16 Identities = 40/98 (40%), Positives = 65/98 (66%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +++ FP ++ EAK L+ GLL++ Sbjct: 329 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIAFPRTL--GPEAKSLLSGLLKK 386 Query: 449 DPSSRIGSNT-GANDIKEHPFFEDIYWPLI--RCMSPP 345 DP+ R+G + A +I +H FF +I W + + +SPP Sbjct: 387 DPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPP 424
>AKT_MLVAT (P31748) AKT kinase transforming protein (EC 2.7.11.1)| Length = 501 Score = 83.2 bits (204), Expect = 6e-16 Identities = 40/98 (40%), Positives = 65/98 (66%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +++ FP ++ EAK L+ GLL++ Sbjct: 350 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTL--GPEAKSLLSGLLKK 407 Query: 449 DPSSRIGSNT-GANDIKEHPFFEDIYWPLI--RCMSPP 345 DP+ R+G + A +I +H FF +I W + + +SPP Sbjct: 408 DPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPP 445
>AKT1_RAT (P47196) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) Length = 480 Score = 83.2 bits (204), Expect = 6e-16 Identities = 40/98 (40%), Positives = 65/98 (66%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +++ FP ++ EAK L+ GLL++ Sbjct: 329 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTL--GPEAKSLLSGLLKK 386 Query: 449 DPSSRIGSNT-GANDIKEHPFFEDIYWPLI--RCMSPP 345 DP+ R+G + A +I +H FF +I W + + +SPP Sbjct: 387 DPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKLSPP 424
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 83.2 bits (204), Expect = 6e-16 Identities = 39/100 (39%), Positives = 63/100 (63%), Gaps = 5/100 (5%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWALG+L+YEM+ G+ PF N F +ILH D+ +P + +S EA ++ + + Sbjct: 587 SVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTK 644 Query: 449 DPSSRIG---SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 +P R+G + G + IK+HPFF++I W L+ + M PP Sbjct: 645 NPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKMKPP 684
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 83.2 bits (204), Expect = 6e-16 Identities = 48/130 (36%), Positives = 71/130 (54%), Gaps = 3/130 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V++ + +IDWW+ GIL+YEML G TPF N KT+ IL+ +L FP + + K Sbjct: 253 VVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFF--NEDVK 310 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWP--LIRCMSPPELDVPLKLIGKES 306 L+ L+ RD S R+G+ G D+K HP+F+++ W L R + P + G S Sbjct: 311 DLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTS 370 Query: 305 QPKVKPEEGV 276 Q PEE + Sbjct: 371 QFDKYPEEDI 380
>KPCB_RAT (P68403) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 82.8 bits (203), Expect = 8e-16 Identities = 46/125 (36%), Positives = 66/125 (52%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++ +P S +S EA Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAV 568 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P R+G G DIKEH FF I W KL KE QP Sbjct: 569 AICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWE--------------KLERKEIQP 614 Query: 299 KVKPE 285 KP+ Sbjct: 615 PYKPK 619
>KPCB_HUMAN (P05771) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 82.8 bits (203), Expect = 8e-16 Identities = 46/125 (36%), Positives = 66/125 (52%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++ +P S +S EA Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAV 568 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P R+G G DIKEH FF I W KL KE QP Sbjct: 569 AICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWE--------------KLERKEIQP 614 Query: 299 KVKPE 285 KP+ Sbjct: 615 PYKPK 619
>PKN2_MOUSE (Q8BWW9) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) Length = 983 Score = 82.8 bits (203), Expect = 8e-16 Identities = 40/107 (37%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+L+YEML G +PF G + ++ F +I++ ++ +P + S EA Sbjct: 827 VLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFL--STEAI 884 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++ LL+R+P R+G+ A D+K+HPFF W + + + PP Sbjct: 885 SIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALMDKKVKPP 931
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 82.8 bits (203), Expect = 8e-16 Identities = 39/100 (39%), Positives = 63/100 (63%), Gaps = 5/100 (5%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWALG+L+YEM+ G+ PF N F +ILH D+ +P + +S EA ++ + + Sbjct: 587 SVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTK 644 Query: 449 DPSSRIG---SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 +P R+G S G + IK+HPFF++I W L+ + + PP Sbjct: 645 NPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPP 684
>KPCB_MOUSE (P68404) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 82.8 bits (203), Expect = 8e-16 Identities = 46/125 (36%), Positives = 66/125 (52%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++ +P S +S EA Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAV 568 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P R+G G DIKEH FF I W KL KE QP Sbjct: 569 AICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWE--------------KLERKEIQP 614 Query: 299 KVKPE 285 KP+ Sbjct: 615 PYKPK 619
>KPCB_BOVIN (P05126) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 672 Score = 82.8 bits (203), Expect = 8e-16 Identities = 46/125 (36%), Positives = 66/125 (52%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++ +P S +S EA Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAV 568 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P R+G G DIKEH FF I W KL KE QP Sbjct: 569 AICKGLITKHPGKRLGCGPEGERDIKEHAFFRYIDWE--------------KLERKEIQP 614 Query: 299 KVKPE 285 KP+ Sbjct: 615 PYKPK 619
>PKN2_RAT (O08874) Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein| kinase C-like 2) (Protein-kinase C-related kinase 2) (Protease-activated kinase 2) (PAK-2) (Fragment) Length = 842 Score = 82.8 bits (203), Expect = 8e-16 Identities = 41/107 (38%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+L+YEML G +PF G + ++ F +I++ ++ +P + S EA Sbjct: 692 VLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFL--STEAI 749 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWP--LIRCMSPP 345 ++ LL+R+P R+G+ A D+K+HPFF W L + + PP Sbjct: 750 SIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALLDKKVKPP 796
>AKT1_HUMAN (P31749) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT) Length = 480 Score = 82.4 bits (202), Expect = 1e-15 Identities = 40/98 (40%), Positives = 63/98 (64%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +++ FP ++ EAK L+ GLL++ Sbjct: 329 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTL--GPEAKSLLSGLLKK 386 Query: 449 DPSSRIGSNT-GANDIKEHPFFEDIYWPLI--RCMSPP 345 DP R+G + A +I +H FF I W + + +SPP Sbjct: 387 DPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPP 424
>KPC4_DROME (P83099) Putative protein kinase C, delta type homolog (EC| 2.7.11.13) Length = 643 Score = 82.0 bits (201), Expect = 1e-15 Identities = 43/107 (40%), Positives = 67/107 (62%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G + +DWW+ G+LLYEML G++PF G + + F++I ++ FP + +S EA Sbjct: 485 IIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFP--VYISAEAT 542 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++ GLL++D + RIGS + A DI +H FF I W L+ R + PP Sbjct: 543 GILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPP 589
>KPCA_MOUSE (P20444) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 81.6 bits (200), Expect = 2e-15 Identities = 43/125 (34%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++++P S+ S EA Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL--SKEAV 565 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P+ R+G G D++EH FF I W KL +E QP Sbjct: 566 SICKGLMTKQPAKRLGCGPEGERDVREHAFFRRIDWE--------------KLENREIQP 611 Query: 299 KVKPE 285 KP+ Sbjct: 612 PFKPK 616
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 81.6 bits (200), Expect = 2e-15 Identities = 38/100 (38%), Positives = 63/100 (63%), Gaps = 5/100 (5%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWALG+L+YEM+ G+ PF N F +ILH D+ +P + +S EA ++ + + Sbjct: 587 SVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTK 644 Query: 449 DPSSRIG---SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 +P R+G + G + IK+HPFF++I W L+ + + PP Sbjct: 645 NPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPP 684
>KPC1_DROME (P05130) Protein kinase C, brain isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(BR)) Length = 679 Score = 81.6 bits (200), Expect = 2e-15 Identities = 42/116 (36%), Positives = 66/116 (56%), Gaps = 1/116 (0%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWA G+LLYEML G+ PF G++ ++ F I ++++P S+ S EAK+ G L + Sbjct: 529 SVDWWAYGVLLYEMLVGQPPFDGEDEEELFAAITDHNVSYPKSL--SKEAKEACKGFLTK 586 Query: 449 DPSSRIG-SNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPKVKPE 285 P+ R+G ++G D++ HPFF I W K+ +E QP KP+ Sbjct: 587 QPNKRLGCGSSGEEDVRLHPFFRRIDWE--------------KIENREVQPPFKPK 628
>SCK1_SCHPO (P50530) Serine/threonine-protein kinase sck1 (EC 2.7.11.1)| Length = 696 Score = 81.6 bits (200), Expect = 2e-15 Identities = 37/101 (36%), Positives = 63/101 (62%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHG 462 G+T +D+W+LG+L++EM G +PF + ++ + NI + FP + +S E + + G Sbjct: 480 GYTKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGV-LSSEGRSFVRG 538 Query: 461 LLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 LL R+P+ R+G+ ++KEHPFF DI W L+ + + PP Sbjct: 539 LLNRNPNHRLGAVADTTELKEHPFFADINWDLLSKKKVQPP 579
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 81.6 bits (200), Expect = 2e-15 Identities = 38/100 (38%), Positives = 63/100 (63%), Gaps = 5/100 (5%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWALG+L+YEM+ G+ PF N F +ILH D+ +P + +S EA ++ + + Sbjct: 586 SVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKAFMTK 643 Query: 449 DPSSRIG---SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 +P R+G + G + IK+HPFF++I W L+ + + PP Sbjct: 644 NPHKRLGCVAAQNGEDAIKQHPFFKEIDWVLLEQKKIKPP 683
>KPCB_RABIT (P05772) Protein kinase C beta type (EC 2.7.11.13) (PKC-beta)| (PKC-B) Length = 670 Score = 81.6 bits (200), Expect = 2e-15 Identities = 45/125 (36%), Positives = 66/125 (52%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++ +P S +S EA Sbjct: 511 IIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKS--MSKEAV 568 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P R+G G DIK+H FF I W KL KE QP Sbjct: 569 AICKGLMTKHPGKRLGCGPEGERDIKDHAFFRYIDWE--------------KLERKEIQP 614 Query: 299 KVKPE 285 KP+ Sbjct: 615 PYKPK 619
>KPCA_RAT (P05696) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 81.3 bits (199), Expect = 2e-15 Identities = 43/125 (34%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++++P S+ S EA Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL--SKEAV 565 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P+ R+G G D++EH FF I W KL +E QP Sbjct: 566 SICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWE--------------KLENREIQP 611 Query: 299 KVKPE 285 KP+ Sbjct: 612 PFKPK 616
>KPCA_RABIT (P10102) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 81.3 bits (199), Expect = 2e-15 Identities = 43/125 (34%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++++P S+ S EA Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL--SKEAV 565 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P+ R+G G D++EH FF I W KL +E QP Sbjct: 566 SICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWE--------------KLENREIQP 611 Query: 299 KVKPE 285 KP+ Sbjct: 612 PFKPK 616
>KPCA_HUMAN (P17252) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 81.3 bits (199), Expect = 2e-15 Identities = 43/125 (34%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++++P S+ S EA Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL--SKEAV 565 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P+ R+G G D++EH FF I W KL +E QP Sbjct: 566 SICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWE--------------KLENREIQP 611 Query: 299 KVKPE 285 KP+ Sbjct: 612 PFKPK 616
>KAPC_ASCSU (P49673) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 337 Score = 81.3 bits (199), Expect = 2e-15 Identities = 45/107 (42%), Positives = 63/107 (58%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI GH +A+DWW+LG+L+YEM+ G PFRGK + + I+ L F S L AK Sbjct: 195 VIGNKGHDTAVDWWSLGVLIYEMMIGIPPFRGKTLDEIYEKIILGKLRFTRSF--DLFAK 252 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCM--SPP 345 L+ LLQ D + R+G+ GA D+ H +F DI W ++ M +PP Sbjct: 253 DLVKKLLQVDRTQRLGNQKDGAADVMNHKWFTDIDWDDVQNMKLTPP 299
>ST38L_HUMAN (Q9Y2H1) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 81.3 bits (199), Expect = 2e-15 Identities = 46/130 (35%), Positives = 71/130 (54%), Gaps = 2/130 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 V G+ DWW+LG+++YEML G PF + ++T+ +++ + L FP +P+S + Sbjct: 294 VFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEK 353 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQ 303 AK LI D +RIG N+G +IK HPFFE + W IR P + + +K I S Sbjct: 354 AKDLILRFC-IDSENRIG-NSGVEEIKGHPFFEGVDWEHIR-ERPAAIPIEIKSIDDTSN 410 Query: 302 PKVKPEEGVI 273 PE ++ Sbjct: 411 FDDFPESDIL 420
>KPCA_BOVIN (P04409) Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha)| (PKC-A) Length = 671 Score = 80.9 bits (198), Expect = 3e-15 Identities = 43/125 (34%), Positives = 67/125 (53%), Gaps = 1/125 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWWA G+LLYEML G+ PF G++ + F +I+ ++++P S+ S EA Sbjct: 508 IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL--SKEAV 565 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 + GL+ + P R+G G D++EH FF I W KL +E QP Sbjct: 566 SICKGLMTKHPGKRLGCGPEGERDVREHAFFRRIDWE--------------KLENREIQP 611 Query: 299 KVKPE 285 KP+ Sbjct: 612 PFKPK 616
>PCK2_SCHPO (P36583) Protein kinase C-like 2 (EC 2.7.11.13)| Length = 1016 Score = 80.9 bits (198), Expect = 3e-15 Identities = 36/90 (40%), Positives = 58/90 (64%), Gaps = 1/90 (1%) Frame = -3 Query: 638 HTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGL 459 +T ++DWWA G+L+Y+ML G++PFRG++ ++ F IL + +P +P ++ ++ L Sbjct: 860 YTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPLYPIHMP--RDSVSILQQL 917 Query: 458 LQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 L RDP R+GS A D+ HPFF +I W Sbjct: 918 LTRDPKKRLGSGPNDAEDVMTHPFFSNINW 947
>AKT2_HUMAN (P31751) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 80.5 bits (197), Expect = 4e-15 Identities = 37/87 (42%), Positives = 58/87 (66%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ ++ F IL +++ FP ++ S EAK L+ GLL++ Sbjct: 330 AVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTL--SPEAKSLLAGLLKK 387 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 DP R+G + A ++ EH FF I W Sbjct: 388 DPKQRLGGGPSDAKEVMEHRFFLSINW 414
>AKT2B_XENLA (Q6IP76) RAC-beta serine/threonine-protein kinase-B (EC 2.7.11.1)| (RAC-PK-beta-B) (Protein kinase Akt-2-B) (Protein kinase B, beta-B) (PKB beta-B) Length = 485 Score = 80.1 bits (196), Expect = 5e-15 Identities = 40/98 (40%), Positives = 61/98 (62%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ ++ F IL ++ FP ++ S EAK L+ GLL++ Sbjct: 334 AVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEETRFPRTL--SPEAKSLLAGLLKK 391 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYWPLI--RCMSPP 345 DP R+G A ++ H FF I W + R +SPP Sbjct: 392 DPKQRLGGGPDDAQEVMSHGFFASINWQDVTERKLSPP 429
>PKN3_MOUSE (Q8K045) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 878 Score = 80.1 bits (196), Expect = 5e-15 Identities = 43/107 (40%), Positives = 60/107 (56%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+LLYEML G PF G ++ F I+ D+ P + S++ Sbjct: 719 VLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSADVPCPHFL--SVQGL 776 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWP--LIRCMSPP 345 +LI LLQ+ P R+G+ A +IK PFF W L R + PP Sbjct: 777 ELIQKLLQKSPEKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQPP 823
>AKT2A_XENLA (Q7ZX15) RAC-beta serine/threonine-protein kinase-A (EC 2.7.11.1)| (RAC-PK-beta-A) (Protein kinase Akt-2-A) (Protein kinase B, beta-A) (PKB beta-A) Length = 486 Score = 80.1 bits (196), Expect = 5e-15 Identities = 39/98 (39%), Positives = 62/98 (63%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ ++ F IL +++ FP ++ S EAK L+ GLL++ Sbjct: 335 AVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTL--SPEAKSLLAGLLKK 392 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYWPLI--RCMSPP 345 DP R+G A ++ H FF I W + R ++PP Sbjct: 393 DPKQRLGGGPNDAQEVMSHRFFVSINWQDVTERKLTPP 430
>AKT3_MOUSE (Q9WUA6) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 479 Score = 80.1 bits (196), Expect = 5e-15 Identities = 37/87 (42%), Positives = 56/87 (64%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +D+ FP ++ S +AK L+ GLL + Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTL--SSDAKSLLSGLLIK 383 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 DP+ R+G A +I H FF + W Sbjct: 384 DPNKRLGGGPDDAKEIMRHSFFSGVNW 410
>AKT3_HUMAN (Q9Y243) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2) Length = 479 Score = 80.1 bits (196), Expect = 5e-15 Identities = 37/87 (42%), Positives = 56/87 (64%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +D+ FP ++ S +AK L+ GLL + Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTL--SSDAKSLLSGLLIK 383 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 DP+ R+G A +I H FF + W Sbjct: 384 DPNKRLGGGPDDAKEIMRHSFFSGVNW 410
>PKN3_HUMAN (Q6P5Z2) Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein| kinase PKN-beta) (Protein-kinase C-related kinase 3) Length = 889 Score = 79.3 bits (194), Expect = 9e-15 Identities = 42/107 (39%), Positives = 60/107 (56%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+T +T A+DWW LG+LLYEML G PF G ++ F I++ D +P + S++ Sbjct: 730 VLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFL--SVQGL 787 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWP--LIRCMSPP 345 + I LLQ+ P R+G+ A +IK PFF W L R + PP Sbjct: 788 EFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPP 834
>KS6A_CAEEL (Q21734) Putative ribosomal protein S6 kinase alpha (EC 2.7.11.1)| Length = 784 Score = 79.3 bits (194), Expect = 9e-15 Identities = 45/131 (34%), Positives = 70/131 (53%), Gaps = 1/131 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI GH+ A D+W+LG+L++EML G PF+G++R T IL L+ P + + EA+ Sbjct: 275 VINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFL--TQEAQ 332 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+ +R+G+ G +IK H FF I + +KL+ KE P Sbjct: 333 SLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDF--------------VKLLNKEIDP 378 Query: 299 KVKPEEGVIDT 267 KP +D+ Sbjct: 379 PFKPALSTVDS 389 Score = 42.4 bits (98), Expect = 0.001 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 6/81 (7%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHK------DLTFPSSIP 495 V+ G+ + D W+LG+LL+ ML G TPF T IL + +T P Sbjct: 622 VLRKQGYDRSCDVWSLGVLLHTMLTGCTPF-AMGPNDTPDQILQRVGDGKISMTHPVWDT 680 Query: 494 VSLEAKQLIHGLLQRDPSSRI 432 +S EAK L+ +L DP+ R+ Sbjct: 681 ISDEAKDLVRKMLDVDPNRRV 701
>AKT1_XENLA (Q98TY9) RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-alpha) (Protein kinase Akt-1) (Protein kinase B, alpha) (PKB alpha) (xAkt) Length = 481 Score = 79.3 bits (194), Expect = 9e-15 Identities = 37/87 (42%), Positives = 56/87 (64%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +++ FP ++ EAK L+ GLL++ Sbjct: 330 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTL--LPEAKSLLSGLLKK 387 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 DP R+G A +I +H FF I W Sbjct: 388 DPKQRLGGGPDDAKEIMQHKFFAGIVW 414
>AKT3_RAT (Q63484) RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) Length = 454 Score = 79.0 bits (193), Expect = 1e-14 Identities = 39/89 (43%), Positives = 58/89 (65%), Gaps = 3/89 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ +K F IL +D+ FP ++ S +AK L+ GLL + Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTL--SSDAKSLLSGLLIK 383 Query: 449 DPSSRIGSNTGANDIKE---HPFFEDIYW 372 DP+ R+G G +D KE H FF + W Sbjct: 384 DPNKRLGG--GPDDPKEIMRHSFFSGVNW 410
>SGK3_HUMAN (Q96BR1) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) Length = 496 Score = 79.0 bits (193), Expect = 1e-14 Identities = 41/105 (39%), Positives = 62/105 (59%), Gaps = 1/105 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI + + +DWW LG +LYEMLYG PF ++ + + NILHK L+ VSL A Sbjct: 332 VIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPG--VSLTAW 389 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW-PLIRCMSPP 345 ++ LL++D +R+G+ +I+ HPFFE + W L++ PP Sbjct: 390 SILEELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPP 434
>AKT2_RAT (P47197) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 79.0 bits (193), Expect = 1e-14 Identities = 36/87 (41%), Positives = 57/87 (65%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ ++ F IL +++ FP ++ EAK L+ GLL++ Sbjct: 330 AVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTL--GPEAKSLLAGLLKK 387 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 DP R+G + A ++ EH FF I W Sbjct: 388 DPKQRLGGGPSDAKEVMEHRFFLSINW 414
>AKT2_MOUSE (Q60823) RAC-beta serine/threonine-protein kinase (EC 2.7.11.1)| (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 79.0 bits (193), Expect = 1e-14 Identities = 36/87 (41%), Positives = 57/87 (65%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG+++YEM+ GR PF ++ ++ F IL +++ FP ++ EAK L+ GLL++ Sbjct: 330 AVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTL--GPEAKSLLAGLLKK 387 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 DP R+G + A ++ EH FF I W Sbjct: 388 DPKQRLGGGPSDAKEVMEHRFFLSINW 414
>KPC1_LYTPI (Q25378) Protein kinase C (EC 2.7.11.13)| Length = 658 Score = 78.6 bits (192), Expect = 2e-14 Identities = 41/98 (41%), Positives = 59/98 (60%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA G+LLYEML G+ PF G++ + F +I+ ++P S +S E+ + G L + Sbjct: 504 AVDWWAFGVLLYEMLAGQPPFDGEDEDELFQSIMEHVPSYPKS--MSRESVTMCKGFLTK 561 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYWPLI--RCMSPP 345 P R+GS TG DI+EH FF I W + R + PP Sbjct: 562 HPGKRLGSGPTGEQDIREHQFFRRIDWEKLANREIQPP 599
>ST38L_MOUSE (Q7TSE6) Serine/threonine-protein kinase 38-like (EC 2.7.11.1)| (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2) Length = 464 Score = 78.6 bits (192), Expect = 2e-14 Identities = 46/130 (35%), Positives = 69/130 (53%), Gaps = 2/130 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNIL--HKDLTFPSSIPVSLE 483 V G+ DWW+LG+++YEML G PF + ++T+ ++ + L FP +PVS + Sbjct: 294 VFMQTGYNKLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKETLAFPPEVPVSEK 353 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQ 303 AK LI D +RIG N G +IK HPFFE + W IR P + + ++ I S Sbjct: 354 AKDLILRFC-TDSENRIG-NGGVEEIKGHPFFEGVDWGHIR-ERPAAIPIEIRSIDDTSN 410 Query: 302 PKVKPEEGVI 273 PE ++ Sbjct: 411 FDDFPESDIL 420
>AKT1_DROME (Q8INB9) RAC serine/threonine-protein kinase (EC 2.7.11.1)| (DRAC-PK) (Akt) (Dakt1) (Protein kinase B) (PKB) Length = 611 Score = 78.6 bits (192), Expect = 2e-14 Identities = 42/109 (38%), Positives = 65/109 (59%), Gaps = 5/109 (4%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ + A+DWW G+++YEM+ GR PF ++ F IL +++ FP +I + EAK Sbjct: 435 VLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNI--TDEAK 492 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKE---HPFFEDIYWP--LIRCMSPP 345 L+ GLL +DP R+G G +D+KE HPFF I W +++ + PP Sbjct: 493 NLLAGLLAKDPKKRLGG--GKDDVKEIQAHPFFASINWTDLVLKKIPPP 539
>SCH9_YEAST (P11792) Serine/threonine-protein kinase SCH9 (EC 2.7.11.1)| Length = 823 Score = 78.2 bits (191), Expect = 2e-14 Identities = 33/94 (35%), Positives = 57/94 (60%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHG 462 G+T +D+W+LG+L++EM G +PF +N +K + I + FP + +S E + + G Sbjct: 587 GYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDV-LSQEGRSFVKG 645 Query: 461 LLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIR 360 LL R+P R+G+ +++ HPFF DI W ++ Sbjct: 646 LLNRNPKHRLGAIDDGRELRAHPFFADIDWEALK 679
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 77.8 bits (190), Expect = 3e-14 Identities = 39/106 (36%), Positives = 64/106 (60%), Gaps = 2/106 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G +T ++DWW+ G+LLYEML G++PF G + + F +I +P I + E+K Sbjct: 519 ILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI--TKESK 576 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++ L +R+P+ R+G +IK HPFF+ I W L+ R + PP Sbjct: 577 DILEKLFEREPTKRLGM---TGNIKIHPFFKTINWTLLEKRRLEPP 619
>KPC2_CAEEL (P90980) Protein kinase C-like 2 (EC 2.7.11.13) (PKC2)| Length = 682 Score = 77.8 bits (190), Expect = 3e-14 Identities = 42/101 (41%), Positives = 61/101 (60%), Gaps = 6/101 (5%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWA G+LL+EML G+ PF G++ + F I ++++P S+ S EA L LL + Sbjct: 527 SVDWWAYGVLLFEMLAGQPPFDGEDEDELFTAITEHNVSYPKSL--SKEAVSLCKALLIK 584 Query: 449 DPSSRIG----SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 +PS R+G + + DIKEHPFF I W I R + PP Sbjct: 585 NPSKRLGCTGDDESASRDIKEHPFFRRIDWFKIETRQIQPP 625
>KS6A5_CHICK (Q5F3L1) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 789 Score = 77.4 bits (189), Expect = 3e-14 Identities = 37/93 (39%), Positives = 55/93 (59%), Gaps = 3/93 (3%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEA--KQLI 468 GH A+DWW++G+L+YE+L G +PF K + I + L P + A K +I Sbjct: 221 GHDKAVDWWSVGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALSKDII 280 Query: 467 HGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 LL +DP R+G T A++IK+HPFF++I W Sbjct: 281 QRLLMKDPKKRLGCGPTDADEIKQHPFFQNINW 313 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 9/79 (11%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH-------KDLTFPSSI--PVS 489 G+ + D W+LG++LY ML G+ PF+ +++ T + L + +F VS Sbjct: 588 GYDESCDLWSLGVILYTMLSGQVPFQSQDKSLTCTSALEIMKKIKKGEFSFEGEAWKNVS 647 Query: 488 LEAKQLIHGLLQRDPSSRI 432 EAK+LI GLL DP+ RI Sbjct: 648 EEAKELIQGLLTVDPNKRI 666
>KPC1_APLCA (Q16974) Calcium-dependent protein kinase C (EC 2.7.11.13) (APL I)| Length = 649 Score = 77.4 bits (189), Expect = 3e-14 Identities = 40/98 (40%), Positives = 60/98 (61%), Gaps = 3/98 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWA G+LLYEML G+ PF G++ ++ F +I ++++P ++ S EA L GLL + Sbjct: 499 SVDWWAYGVLLYEMLAGQPPFDGEDEEELFTSITDHNVSYPKAL--SREAVSLCKGLLTK 556 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYWPLI--RCMSPP 345 P+ R+G G DIK+ FF I W I R + PP Sbjct: 557 TPAKRLGCGPNGERDIKDRAFFRPIQWERIELREVQPP 594
>SGK1_HUMAN (O00141) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 77.4 bits (189), Expect = 3e-14 Identities = 38/85 (44%), Positives = 52/85 (61%) Frame = -3 Query: 626 IDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQRD 447 +DWW LG +LYEMLYG PF +N + + NIL+K L +I S A+ L+ GLLQ+D Sbjct: 278 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS--ARHLLEGLLQKD 335 Query: 446 PSSRIGSNTGANDIKEHPFFEDIYW 372 + R+G+ +IK H FF I W Sbjct: 336 RTKRLGAKDDFMEIKSHVFFSLINW 360
>KAPC_DICDI (P34099) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 648 Score = 77.4 bits (189), Expect = 3e-14 Identities = 42/96 (43%), Positives = 55/96 (57%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I GH A+DWWALGIL++EML G PF + + IL +TFP V +AK Sbjct: 502 IIQSKGHGKAVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDV--DAK 559 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 LI LL D + R+G+ GA D+K H +F DI W Sbjct: 560 DLIKRLLTADRTRRLGALKDGALDVKNHRWFSDINW 595
>CBK1_KLULA (P31034) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 718 Score = 77.0 bits (188), Expect = 5e-14 Identities = 39/101 (38%), Positives = 59/101 (58%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLI 468 G+ DWW+LG ++YE L G PF + ++T+ I++ + L FP I +S EA+ LI Sbjct: 546 GYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLI 605 Query: 467 HGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 LL +R+G + GA++IK HPFF + W IR + P Sbjct: 606 RRLLTHS-ENRLGRHGGADEIKAHPFFSGVDWNTIRQVEAP 645
>CEK1_SCHPO (P38938) Serine/threonine-protein kinase cek1 (EC 2.7.11.1)| Length = 1338 Score = 77.0 bits (188), Expect = 5e-14 Identities = 41/111 (36%), Positives = 62/111 (55%), Gaps = 2/111 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSI--PVSLE 483 VI G A DWW+LG +++E L+G PF + + F NIL + + +P+ + S Sbjct: 868 VILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILARRINWPAEVFTAESSV 927 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVP 330 A LI LL +P++R+G+N G +IK HPFF+ + W I PP + P Sbjct: 928 ALDLIDRLLCMNPANRLGAN-GVEEIKAHPFFKSVNWDTILEEDPPFVPKP 977
>SGK1_MOUSE (Q9WVC6) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 77.0 bits (188), Expect = 5e-14 Identities = 38/85 (44%), Positives = 52/85 (61%) Frame = -3 Query: 626 IDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQRD 447 +DWW LG +LYEMLYG PF +N + + NIL+K L +I S A+ L+ GLLQ+D Sbjct: 278 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS--ARHLLEGLLQKD 335 Query: 446 PSSRIGSNTGANDIKEHPFFEDIYW 372 + R+G+ +IK H FF I W Sbjct: 336 RTKRLGAKDDFMEIKSHIFFSLINW 360
>KPCL_MOUSE (P23298) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 77.0 bits (188), Expect = 5e-14 Identities = 37/99 (37%), Positives = 62/99 (62%), Gaps = 4/99 (4%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA+G+LLYEML G PF +N F IL+ ++ +P+ + +A+ ++ + + Sbjct: 534 AVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWL--HEDARGILKSFMTK 591 Query: 449 DPSSRIGSNT--GANDIKEHPFFEDIYWPLI--RCMSPP 345 +P+ R+GS T G ++I HPFF++I W + R + PP Sbjct: 592 NPTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPP 630
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 76.6 bits (187), Expect = 6e-14 Identities = 41/122 (33%), Positives = 68/122 (55%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G + ++DWW+ G+LLYEML G++PF G++ ++ F++I + +P + EAK Sbjct: 550 ILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL--EKEAK 607 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 L+ L R+P R+G DI++HP F +I W + E+D P + PK Sbjct: 608 DLLVKLFVREPEKRLGVR---GDIRQHPLFREINW---EELERKEIDPPFR-------PK 654 Query: 296 VK 291 VK Sbjct: 655 VK 656
>CBK1_YEAST (P53894) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell| wall biosynthesis kinase) Length = 756 Score = 76.6 bits (187), Expect = 6e-14 Identities = 39/101 (38%), Positives = 58/101 (57%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLI 468 G+ DWW+LG ++YE L G PF + ++T+ I++ + L FP I +S EA+ LI Sbjct: 587 GYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLI 646 Query: 467 HGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 LL R+G + GA++IK HPFF + W IR + P Sbjct: 647 RRLLTH-ADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAP 686
>KPCD_CANFA (Q5PU49) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 76.6 bits (187), Expect = 6e-14 Identities = 39/106 (36%), Positives = 64/106 (60%), Gaps = 2/106 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G ++ ++DWW+ G+LLYEML G++PF G + + F +I +P I + E+K Sbjct: 517 ILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI--TKESK 574 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++ LL+RD + R+G +IK HPFF+ I W L+ R + PP Sbjct: 575 DILEKLLERDTTKRLGV---TGNIKIHPFFKTINWTLLEKRAVEPP 617
>SGK3_MOUSE (Q9ERE3) Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like) (Cytokine independent survival kinase) Length = 496 Score = 76.6 bits (187), Expect = 6e-14 Identities = 40/105 (38%), Positives = 61/105 (58%), Gaps = 1/105 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI + + +DWW LG +LYEMLYG PF ++ + + NILHK L VSL A Sbjct: 332 VIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPG--VSLTAW 389 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW-PLIRCMSPP 345 ++ LL+++ +R+G+ +I+ HPFFE + W L++ PP Sbjct: 390 SILEELLEKNRQNRLGAKEDFLEIQNHPFFESLSWTDLVQKKIPP 434
>SGK1_RABIT (Q9XT18) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 431 Score = 76.3 bits (186), Expect = 8e-14 Identities = 37/85 (43%), Positives = 52/85 (61%) Frame = -3 Query: 626 IDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQRD 447 +DWW LG +LYEMLYG PF +N + + NIL+K L +I S A+ L+ GLLQ+D Sbjct: 278 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNS--ARHLLEGLLQKD 335 Query: 446 PSSRIGSNTGANDIKEHPFFEDIYW 372 + R+G+ +I+ H FF I W Sbjct: 336 RTKRLGAKDDFMEIRNHVFFSLINW 360
>CBK1_CANGA (Q6FP74) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 773 Score = 76.3 bits (186), Expect = 8e-14 Identities = 38/101 (37%), Positives = 58/101 (57%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLI 468 G+ DWW+LG ++YE L G PF + ++T+ I++ + L FP + +S EA+ LI Sbjct: 601 GYGQDCDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPEDVHISYEAEDLI 660 Query: 467 HGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 LL + R+G GA++IK HPFF + W IR + P Sbjct: 661 RRLLTHS-NQRLGRQGGADEIKSHPFFRGVDWNTIRQVEAP 700
>SGK1_RAT (Q06226) Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 1) Length = 430 Score = 75.9 bits (185), Expect = 1e-13 Identities = 36/85 (42%), Positives = 52/85 (61%) Frame = -3 Query: 626 IDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQRD 447 +DWW LG +LYEMLYG PF +N + + NIL+K L + ++ A+ L+ GLLQ+D Sbjct: 278 VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKN---ITNSARHLLEGLLQKD 334 Query: 446 PSSRIGSNTGANDIKEHPFFEDIYW 372 + R+G+ +IK H FF I W Sbjct: 335 RTKRLGAKDDFMEIKSHIFFSLINW 359
>CBK1_ASHGO (Q754N7) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 719 Score = 75.9 bits (185), Expect = 1e-13 Identities = 40/101 (39%), Positives = 58/101 (57%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLI 468 G+ DWW+LG ++YE L G PF + ++T+ I++ + L FP I +S EA+ LI Sbjct: 547 GYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLVFPDDIHISYEAEDLI 606 Query: 467 HGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 LL R+G + GAN+IK HPFF + W IR + P Sbjct: 607 RRLLSH-ADERLGRH-GANEIKNHPFFRGVDWETIRQVGAP 645
>MAST1_HUMAN (Q9Y2H9) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 75.9 bits (185), Expect = 1e-13 Identities = 38/96 (39%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 VI G+ +DWWA+GI+LYE L G PF G ++ F ++ D+ +P + EA Sbjct: 558 VILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTEA 617 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 + LI LLQ +P R+G+ GA ++K+H FF D+ W Sbjct: 618 QLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDW 652
>KRAC_DICDI (P54644) RAC-family serine/threonine-protein kinase homolog (EC| 2.7.11.1) Length = 444 Score = 75.9 bits (185), Expect = 1e-13 Identities = 39/95 (41%), Positives = 56/95 (58%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ G G+ +DWW+ G LLYEML G PF ++ ++ + I+ + L+FP I S +A+ Sbjct: 290 VLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMMEKLSFPHFI--SPDAR 347 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 L+ LL+RDP R+ N IK HPFF I W Sbjct: 348 SLLEQLLERDPEKRLAD---PNLIKRHPFFRSIDW 379
>CBK1_PNECA (Q6TGC6) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 507 Score = 75.9 bits (185), Expect = 1e-13 Identities = 41/106 (38%), Positives = 61/106 (57%), Gaps = 2/106 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 + T G+ DWW+LG +++E L G PF +N +T+ I++ ++L FP + +S E Sbjct: 342 IFTQHGYGQECDWWSLGAIMFECLIGWPPFCSENAHETYRKIINWRENLYFPEDLHLSAE 401 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 A+ LI LL R+G GANDIK HPFF + W IR ++ P Sbjct: 402 AEDLIRKLL-TSADQRLG-RYGANDIKLHPFFRGVNWDTIREINAP 445
>SGK2_RAT (Q8R4U9) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) (Fragment) Length = 302 Score = 75.5 bits (184), Expect = 1e-13 Identities = 38/86 (44%), Positives = 49/86 (56%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG +LYEML+G PF + + + NILH+ L P V+ A L+ GLL + Sbjct: 197 AVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVA--ACDLLQGLLHK 254 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYW 372 D R+GS DIK H FF I W Sbjct: 255 DQRQRLGSKEDFLDIKNHMFFSPINW 280
>SGK2_MOUSE (Q9QZS5) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 367 Score = 75.5 bits (184), Expect = 1e-13 Identities = 38/86 (44%), Positives = 49/86 (56%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG +LYEML+G PF + + + NILH+ L P V+ A L+ GLL + Sbjct: 214 AVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVA--ACDLLQGLLHK 271 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYW 372 D R+GS DIK H FF I W Sbjct: 272 DQRQRLGSKEDFLDIKNHMFFSPINW 297
>PRKX_HUMAN (P51817) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (Protein kinase PKX1) Length = 358 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/107 (40%), Positives = 57/107 (53%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI GH A+DWWALGIL++EML G PF N + IL + FP + K Sbjct: 215 VIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHL--DFHVK 272 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLI--RCMSPP 345 LI LL D + R+G+ GAND+K H +F + W + R + PP Sbjct: 273 DLIKKLLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPP 319
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 75.5 bits (184), Expect = 1e-13 Identities = 40/122 (32%), Positives = 68/122 (55%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G + ++DWW+ G+L+YEML G++PF G++ ++ F++I + +P + EAK Sbjct: 550 ILLGQKYNHSVDWWSFGVLVYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL--EREAK 607 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQPK 297 L+ L R+P R+G DI++HP F +I W + E+D P + PK Sbjct: 608 DLLVKLFVREPEKRLGVR---GDIRQHPLFREINW---EELERKEIDPPFR-------PK 654 Query: 296 VK 291 VK Sbjct: 655 VK 656
>KPCL_RAT (Q64617) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 683 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/99 (37%), Positives = 61/99 (61%), Gaps = 4/99 (4%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA+G+LLYEML G PF +N F IL+ ++ +P+ + +A ++ + + Sbjct: 534 AVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWL--HEDATGILKSFMTK 591 Query: 449 DPSSRIGSNT--GANDIKEHPFFEDIYWPLI--RCMSPP 345 +P+ R+GS T G ++I HPFF++I W + R + PP Sbjct: 592 NPTMRLGSLTQGGEHEILRHPFFKEIDWVQLNHRQLEPP 630
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 75.1 bits (183), Expect = 2e-13 Identities = 38/106 (35%), Positives = 63/106 (59%), Gaps = 2/106 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G ++ ++DWW+ G+LLYEML G++PF G + + F +I +P I + E+K Sbjct: 517 ILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI--TKESK 574 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++ L +RDP R+G +I+ HPFF+ I W L+ R + PP Sbjct: 575 DIMEKLFERDPDKRLGV---TGNIRIHPFFKTINWSLLEKRKVEPP 617
>KS6A4_MOUSE (Q9Z2B9) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK) Length = 773 Score = 75.1 bits (183), Expect = 2e-13 Identities = 36/94 (38%), Positives = 56/94 (59%), Gaps = 3/94 (3%) Frame = -3 Query: 644 AGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSL--EAKQL 471 AGH A+DWW+LGILL+E+L G +PF + + T + + L P+ + A+ L Sbjct: 213 AGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIGPVAQDL 272 Query: 470 IHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 + LL +DP R+G+ GA ++K HPFF+ + W Sbjct: 273 LQRLLCKDPKKRLGAGPQGAQEVKSHPFFQGLDW 306 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 9/79 (11%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFR---GKNRKKTFYNILHK------DLTFPSSIPVS 489 G+ + D W+LG++LY ML G+ PF+ G+ + I+ K L + VS Sbjct: 585 GYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVS 644 Query: 488 LEAKQLIHGLLQRDPSSRI 432 EAK+L+ GLL DP+ R+ Sbjct: 645 EEAKELVRGLLTVDPAKRL 663
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 75.1 bits (183), Expect = 2e-13 Identities = 38/106 (35%), Positives = 64/106 (60%), Gaps = 2/106 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G ++ ++DWW+ G+LLYEML G++PF G + + F +I +P I + E+K Sbjct: 517 ILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI--TKESK 574 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 ++ L +RDP+ R+G +I+ HPFF+ I W L+ R + PP Sbjct: 575 DIMEKLFERDPAKRLGV---TGNIRLHPFFKTINWNLLEKRKVEPP 617
>MAST1_MOUSE (Q9R1L5) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1566 Score = 74.7 bits (182), Expect = 2e-13 Identities = 37/96 (38%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 VI G+ +DWWA+GI+LYE L G PF G ++ F ++ D+ +P + +A Sbjct: 559 VILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDA 618 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 + LI LLQ +P R+G+ GA ++K+H FF D+ W Sbjct: 619 QLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDW 653
>STK38_HUMAN (Q15208) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 74.7 bits (182), Expect = 2e-13 Identities = 48/149 (32%), Positives = 74/149 (49%), Gaps = 3/149 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 V G+ DWW+LG+++YEML G PF + ++T+ +++ + LTFP +P+S + Sbjct: 293 VFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEK 352 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQ 303 AK LI + RIG+ G +IK + FFE + W IR P + + +K I S Sbjct: 353 AKDLILRFC-CEWEHRIGA-PGVEEIKSNSFFEGVDWEHIR-ERPAAISIEIKSIDDTSN 409 Query: 302 PKVKPEEGVI-DTF*GGNDARTDCTMSTW 219 PE ++ T N TD W Sbjct: 410 FDEFPESDILKPTVATSNHPETDYKNKDW 438
>MAST1_RAT (Q810W7) Microtubule-associated serine/threonine-protein kinase 1| (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase) Length = 1570 Score = 74.7 bits (182), Expect = 2e-13 Identities = 37/96 (38%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 VI G+ +DWWA+GI+LYE L G PF G ++ F ++ D+ +P + +A Sbjct: 560 VILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDA 619 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 + LI LLQ +P R+G+ GA ++K+H FF D+ W Sbjct: 620 QLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDW 654
>GRK2_CAEEL (Q09639) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 707 Score = 74.7 bits (182), Expect = 2e-13 Identities = 39/107 (36%), Positives = 65/107 (60%), Gaps = 6/107 (5%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFR---GKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 G + S+ DW++LG +LY++L G +PFR K++ + L +D+ P+ +S + + Sbjct: 366 GVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNE-GLSKDCR 424 Query: 476 QLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 L+ GLL+RD R+G G ++KEHPFF+D+ W + R M+PP Sbjct: 425 DLLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPP 471
>KS6A5_MOUSE (Q8C050) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK) Length = 863 Score = 74.7 bits (182), Expect = 2e-13 Identities = 39/94 (41%), Positives = 53/94 (56%), Gaps = 3/94 (3%) Frame = -3 Query: 644 AGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQL 471 +GH A+DWW+LG+L+YE+L G +PF K + I + L P +S AK L Sbjct: 229 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDL 288 Query: 470 IHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 + LL +DP R+G A +IKEH FFE I W Sbjct: 289 LQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKW 322 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 9/84 (10%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKT-------FYNILHKDLTFPSSI 498 ++T G+ + D W+LG++LY ML G+ PF+ +R T I D +F Sbjct: 657 LLTHNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEA 716 Query: 497 --PVSLEAKQLIHGLLQRDPSSRI 432 VS EAK LI GLL DP+ R+ Sbjct: 717 WKNVSQEAKDLIQGLLTVDPNKRL 740
>CBK1_YARLI (Q6CFS5) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 588 Score = 74.3 bits (181), Expect = 3e-13 Identities = 37/101 (36%), Positives = 59/101 (58%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLI 468 G+ DWW+LG +++E L G PF + ++T++ I++ + L FP + +S E++ LI Sbjct: 432 GYGQECDWWSLGAIMFECLVGWPPFCSEQPRETYHKIINWRETLQFPDDVHLSPESEDLI 491 Query: 467 HGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 LL +R+G GAN+IK HPFF + W IR + P Sbjct: 492 RRLL-TSSENRLGRIGGANEIKSHPFFRGVDWSSIREFNAP 531
>KS6A5_PONPY (Q5R4K3) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1)| Length = 802 Score = 74.3 bits (181), Expect = 3e-13 Identities = 39/94 (41%), Positives = 54/94 (57%), Gaps = 3/94 (3%) Frame = -3 Query: 644 AGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQL 471 +GH A+DWW+LG+L+YE+L G +PF K + I + L P +S AK L Sbjct: 230 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDL 289 Query: 470 IHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 I LL +DP R+G A++IKEH FF+ I W Sbjct: 290 IQHLLMKDPKKRLGCGPRDADEIKEHLFFQKINW 323 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/79 (37%), Positives = 41/79 (51%), Gaps = 9/79 (11%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKT-------FYNILHKDLTFPSSI--PVS 489 G+ + D W+LG++LY ML G+ PF+ +R T I D +F VS Sbjct: 598 GYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVS 657 Query: 488 LEAKQLIHGLLQRDPSSRI 432 EAK LI GLL DP+ R+ Sbjct: 658 QEAKDLIQGLLTVDPNKRL 676
>KS6A5_HUMAN (O75582) Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL) Length = 802 Score = 74.3 bits (181), Expect = 3e-13 Identities = 39/94 (41%), Positives = 54/94 (57%), Gaps = 3/94 (3%) Frame = -3 Query: 644 AGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQL 471 +GH A+DWW+LG+L+YE+L G +PF K + I + L P +S AK L Sbjct: 230 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDL 289 Query: 470 IHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 I LL +DP R+G A++IKEH FF+ I W Sbjct: 290 IQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINW 323 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/79 (37%), Positives = 41/79 (51%), Gaps = 9/79 (11%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKT-------FYNILHKDLTFPSSI--PVS 489 G+ + D W+LG++LY ML G+ PF+ +R T I D +F VS Sbjct: 598 GYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVS 657 Query: 488 LEAKQLIHGLLQRDPSSRI 432 EAK LI GLL DP+ R+ Sbjct: 658 QEAKDLIQGLLTVDPNKRL 676
>MRCKA_RAT (O54874) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) Length = 1732 Score = 73.9 bits (180), Expect = 4e-13 Identities = 46/104 (44%), Positives = 62/104 (59%), Gaps = 6/104 (5%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSI-PVSLEAKQLIHGLLQ 453 DWW+LG+ +YEMLYG TPF ++ +T+ I+ HK+ FP+ + VS AK LI L+ Sbjct: 264 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPTQVTDVSENAKDLIRRLI- 322 Query: 452 RDPSSRIGSNTGANDIKEHPFFEDIYWPLIR-CMSP--PELDVP 330 R+G N G D K+HPFF I W IR C +P PE+ P Sbjct: 323 CSREHRLGQN-GIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSP 365
>MRCKA_HUMAN (Q5VT25) Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1)| (CDC42-binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha Length = 1732 Score = 73.9 bits (180), Expect = 4e-13 Identities = 46/104 (44%), Positives = 62/104 (59%), Gaps = 6/104 (5%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSI-PVSLEAKQLIHGLLQ 453 DWW+LG+ +YEMLYG TPF ++ +T+ I+ HK+ FP+ + VS AK LI L+ Sbjct: 264 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLI- 322 Query: 452 RDPSSRIGSNTGANDIKEHPFFEDIYWPLIR-CMSP--PELDVP 330 R+G N G D K+HPFF I W IR C +P PE+ P Sbjct: 323 CSREHRLGQN-GIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSP 365
>KAPB_SCHPO (P40376) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) Length = 512 Score = 73.9 bits (180), Expect = 4e-13 Identities = 42/100 (42%), Positives = 59/100 (59%), Gaps = 2/100 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSI-PVSLEA 480 +I+ + A DWW+LGIL++EML G PF +N K + NIL + +PS P S++ Sbjct: 368 IISLKPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYENILEGKVNYPSYFSPASID- 426 Query: 479 KQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLI 363 L+ LLQRD + R G+ G+ DI HP+F DI W I Sbjct: 427 --LLSHLLQRDITCRYGNLKDGSMDIIMHPWFRDISWDKI 464
>KPCL_HUMAN (P24723) Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta)| (PKC-L) Length = 682 Score = 73.9 bits (180), Expect = 4e-13 Identities = 37/99 (37%), Positives = 60/99 (60%), Gaps = 4/99 (4%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA+G+LLYEML G PF +N F IL+ ++ +P+ + +A ++ + + Sbjct: 533 AVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWL--HEDATGILKSFMTK 590 Query: 449 DPSSRIGSNT--GANDIKEHPFFEDIYWPLI--RCMSPP 345 +P+ R+GS T G + I HPFF++I W + R + PP Sbjct: 591 NPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPP 629
>KPC1_CANAL (P43057) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1097 Score = 73.9 bits (180), Expect = 4e-13 Identities = 35/105 (33%), Positives = 63/105 (60%), Gaps = 2/105 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++ G + ++DWWA G+LL++ML ++PF+G + F I + ++ +P I +S + Sbjct: 941 IVAGKAYDRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIENDEVKYP--INLSRQTV 998 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDI-YWPLIRCMSP 348 ++ LL +DPS R+GS A +I EHP+F D+ + ++ C P Sbjct: 999 LVLQALLTKDPSQRLGSGPKDAEEIMEHPYFHDVNFDDVLNCRIP 1043
>SGK2_HUMAN (Q9HBY8) Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1)| (Serum/glucocorticoid-regulated kinase 2) Length = 427 Score = 73.6 bits (179), Expect = 5e-13 Identities = 36/86 (41%), Positives = 49/86 (56%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW LG +LYEML+G PF ++ + + NILH+ L P V+ A L+ LL + Sbjct: 274 AVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVA--ACDLLQSLLHK 331 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYW 372 D R+GS +IK H FF I W Sbjct: 332 DQRQRLGSKADFLEIKNHVFFSPINW 357
>AKT2_CAEEL (Q9XTG7) Serine/threonine-protein kinase akt-2 (EC 2.7.11.1)| (Protein kinase B akt-2) (PKB akt-2) Length = 528 Score = 73.6 bits (179), Expect = 5e-13 Identities = 37/96 (38%), Positives = 56/96 (58%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI + ++DWW +G+++YEM+ GR PF K K F I DL FP+ + S EA Sbjct: 349 VIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRL--SPEAV 406 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 L+ GLL+R P+ R+G+ A ++ FF+D+ W Sbjct: 407 TLLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDW 442
>KPCG_HUMAN (P05129) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 73.2 bits (178), Expect = 7e-13 Identities = 37/105 (35%), Positives = 59/105 (56%), Gaps = 1/105 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWW+ G+LLYEML G+ PF G++ ++ F I+ + +T+P S+ S EA Sbjct: 526 IIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSL--SREAV 583 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPP 345 + G L + P R+GS G I+ H FF I W + + P Sbjct: 584 AICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIP 628
>MRCKB_RAT (Q7TT49) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 73.2 bits (178), Expect = 7e-13 Identities = 41/96 (42%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD--LTFPSSI-PVSLEAKQLIHGLLQ 453 DWW+LG+ +YEMLYG TPF ++ +T+ I++ + FPS + VS EAK LI L+ Sbjct: 263 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI- 321 Query: 452 RDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 R+G N G D K+H FFE + W IR + P Sbjct: 322 CSRERRLGQN-GIEDFKKHAFFEGLNWENIRNLEAP 356
>MRCKB_MOUSE (Q7TT50) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1713 Score = 73.2 bits (178), Expect = 7e-13 Identities = 41/96 (42%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD--LTFPSSI-PVSLEAKQLIHGLLQ 453 DWW+LG+ +YEMLYG TPF ++ +T+ I++ + FPS + VS EAK LI L+ Sbjct: 263 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI- 321 Query: 452 RDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 R+G N G D K+H FFE + W IR + P Sbjct: 322 CSRERRLGQN-GIEDFKKHAFFEGLNWENIRNLEAP 356
>MRCKB_HUMAN (Q9Y5S2) Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1)| (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta) Length = 1711 Score = 73.2 bits (178), Expect = 7e-13 Identities = 41/96 (42%), Positives = 57/96 (59%), Gaps = 3/96 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD--LTFPSSI-PVSLEAKQLIHGLLQ 453 DWW+LG+ +YEMLYG TPF ++ +T+ I++ + FPS + VS EAK LI L+ Sbjct: 263 DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLI- 321 Query: 452 RDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 R+G N G D K+H FFE + W IR + P Sbjct: 322 CSRERRLGQN-GIEDFKKHAFFEGLNWENIRNLEAP 356
>KPC2_APLCA (Q16975) Calcium-independent protein kinase C (EC 2.7.11.13) (APL| II) Length = 743 Score = 73.2 bits (178), Expect = 7e-13 Identities = 39/104 (37%), Positives = 61/104 (58%), Gaps = 6/104 (5%) Frame = -3 Query: 638 HTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGL 459 + +++DWWALG+L+YEM+ G+ PF N F +ILH D+ +P + +S EA ++ G Sbjct: 579 YDASVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP--VWLSKEAVSILKGF 636 Query: 458 LQRDPSSRIGSNTG---ANDIKEHPFF-EDIYWPLI--RCMSPP 345 + ++P+ R+G T I HPFF E I W + R + PP Sbjct: 637 MTKNPAKRLGCVTTQGCEKAILVHPFFHEKIDWEALEQRKVKPP 680
>PRKX_MOUSE (Q922R0) Serine/threonine-protein kinase PRKX (EC 2.7.11.1)| (PKA-related protein kinase) Length = 355 Score = 73.2 bits (178), Expect = 7e-13 Identities = 43/107 (40%), Positives = 57/107 (53%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VI GH A+DWWALGIL++EML G PF N + IL + FP + +K Sbjct: 212 VIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILACKIDFPRQL--DFTSK 269 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLI--RCMSPP 345 LI LL D + R+G+ GA DIK H +F + W + R + PP Sbjct: 270 DLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLKPP 316
>KPCG_BOVIN (P05128) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (Fragment) Length = 682 Score = 72.8 bits (177), Expect = 9e-13 Identities = 36/96 (37%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWW+ G+LLYEML G+ PF G++ ++ F I+ + +T+P S+ S EA Sbjct: 511 IIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSL--SREAV 568 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 + G L + P+ R+GS G I+ H FF I W Sbjct: 569 AICKGFLTKHPAKRLGSGPDGEPTIRAHGFFRWIDW 604
>AKT1_CAEEL (Q17941) Serine/threonine-protein kinase akt-1 (EC 2.7.11.1)| (Protein kinase B akt-1) (PKB akt-1) Length = 541 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/86 (41%), Positives = 52/86 (60%), Gaps = 1/86 (1%) Frame = -3 Query: 626 IDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQRD 447 +DWW +G+++YEM+ GR PF K+ K F I+ DL FPS + S EA+ L+ GLL +D Sbjct: 372 VDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKL--SQEARTLLTGLLVKD 429 Query: 446 PSSRIGSN-TGANDIKEHPFFEDIYW 372 P+ R+G A +I FF + W Sbjct: 430 PTQRLGGGPEDALEICRADFFRTVDW 455
>KAPB_YEAST (P06245) cAMP-dependent protein kinase type 2 (EC 2.7.11.11) (PKA| 2) Length = 380 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/96 (37%), Positives = 55/96 (57%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 VIT + ++DWW+LG+L+YEML G TPF KT+ IL + +P + Sbjct: 236 VITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYF--HPDVV 293 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ L+ D + RIG+ +G+ DIK HP+F ++ W Sbjct: 294 DLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVW 329
>KPCG_RAT (P63319) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWW+ G+LLYEML G+ PF G++ ++ F I+ + +T+P S+ S EA Sbjct: 526 IIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSL--SREAV 583 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 + G L + P R+GS G I+ H FF I W Sbjct: 584 AICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPCG_RABIT (P10829) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| (PKC-delta) Length = 697 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWW+ G+LLYEML G+ PF G++ ++ F I+ + +T+P S+ S EA Sbjct: 526 IIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSL--SREAV 583 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 + G L + P R+GS G I+ H FF I W Sbjct: 584 AICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPCG_MOUSE (P63318) Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma)| Length = 697 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + ++DWW+ G+LLYEML G+ PF G++ ++ F I+ + +T+P S+ S EA Sbjct: 526 IIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSL--SREAV 583 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 + G L + P R+GS G I+ H FF I W Sbjct: 584 AICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDW 619
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/100 (36%), Positives = 58/100 (58%), Gaps = 5/100 (5%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 ++DWWALG+L+YEM+ G+ PF N F IL+ D+ +P + +S EA ++ + + Sbjct: 557 SVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYP--VWLSKEAVNILKAFMTK 614 Query: 449 DPSSRIG---SNTGANDIKEHPFFEDIYWPLI--RCMSPP 345 + R+G S G + I+ HPFF +I W + R + PP Sbjct: 615 NAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPP 654
>KPCZ_RABIT (O19111) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 591 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 9/107 (8%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF-------RGKNRKKTFYNILHKDLTFPSSI 498 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P + Sbjct: 421 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 480 Query: 497 PVSLEAKQLIHGLLQRDPSSRIG--SNTGANDIKEHPFFEDIYWPLI 363 S++A ++ G L +DP R+G TG +DIK H FF I W L+ Sbjct: 481 --SVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 525
>KPCZ_RAT (P09217) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 9/107 (8%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF-------RGKNRKKTFYNILHKDLTFPSSI 498 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P + Sbjct: 422 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 481 Query: 497 PVSLEAKQLIHGLLQRDPSSRIG--SNTGANDIKEHPFFEDIYWPLI 363 S++A ++ G L +DP R+G TG +DIK H FF I W L+ Sbjct: 482 --SVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 526
>KPCZ_MOUSE (Q02956) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 9/107 (8%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF-------RGKNRKKTFYNILHKDLTFPSSI 498 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P + Sbjct: 422 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 481 Query: 497 PVSLEAKQLIHGLLQRDPSSRIG--SNTGANDIKEHPFFEDIYWPLI 363 S++A ++ G L +DP R+G TG +DIK H FF I W L+ Sbjct: 482 --SVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 526
>KPCZ_HUMAN (Q05513) Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)| Length = 592 Score = 72.4 bits (176), Expect = 1e-12 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 9/107 (8%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF-------RGKNRKKTFYNILHKDLTFPSSI 498 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P + Sbjct: 422 ILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFL 481 Query: 497 PVSLEAKQLIHGLLQRDPSSRIG--SNTGANDIKEHPFFEDIYWPLI 363 S++A ++ G L +DP R+G TG +DIK H FF I W L+ Sbjct: 482 --SVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLL 526
>STK38_MOUSE (Q91VJ4) Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1| protein kinase) (Nuclear Dbf2-related kinase 1) Length = 465 Score = 72.0 bits (175), Expect = 1e-12 Identities = 45/133 (33%), Positives = 71/133 (53%), Gaps = 5/133 (3%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 V G+ DWW+LG+++YEML G PF + ++T+ +++ + LTFP +PVS + Sbjct: 293 VFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPVSEK 352 Query: 482 AKQLIHGLLQR---DPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGK 312 AK GL+ R + RIG+ G +IK + FFE + W IR P + + +K I Sbjct: 353 AK----GLILRFCCEWEHRIGA-PGVEEIKNNLFFEGVDWEHIR-ERPAAISIEIKSIDD 406 Query: 311 ESQPKVKPEEGVI 273 S PE ++ Sbjct: 407 TSNFDEFPESDIL 419
>KS6A4_HUMAN (O75676) Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear| mitogen-and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB) Length = 772 Score = 72.0 bits (175), Expect = 1e-12 Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 3/102 (2%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQLI 468 GH A+DWW+LGILL+E+L G +PF + + T + + L P + A+ L+ Sbjct: 214 GHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLL 273 Query: 467 HGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPP 345 LL +DP R+G+ GA +++ HPFF+ + W + P Sbjct: 274 QRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIP 315 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 9/79 (11%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFR---GKNRKKTFYNILHK------DLTFPSSIPVS 489 G+ + D W+LG++LY ML G+ PF+ G+ + I+ K L + VS Sbjct: 585 GYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVS 644 Query: 488 LEAKQLIHGLLQRDPSSRI 432 EAK+L+ GLL DP+ R+ Sbjct: 645 EEAKELVRGLLTVDPAKRL 663
>KPC1_YEAST (P24583) Protein kinase C-like 1 (EC 2.7.11.13) (PKC 1)| Length = 1151 Score = 72.0 bits (175), Expect = 1e-12 Identities = 35/88 (39%), Positives = 55/88 (62%), Gaps = 1/88 (1%) Frame = -3 Query: 638 HTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGL 459 +T A+DWWA G+LLY+ML ++PF G + + F IL + +P I ++ E Q+ GL Sbjct: 1001 YTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYP--IDMAGEIVQIFQGL 1058 Query: 458 LQRDPSSRIGSN-TGANDIKEHPFFEDI 378 L +DP R+G+ A+++ E PFF +I Sbjct: 1059 LTKDPEKRLGAGPRDADEVMEEPFFRNI 1086
>KPC1_NEUCR (P87253) Protein kinase C-like (EC 2.7.11.13)| Length = 1142 Score = 71.2 bits (173), Expect = 2e-12 Identities = 37/100 (37%), Positives = 60/100 (60%), Gaps = 3/100 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA G+L+Y+ML ++PFRG++ + + IL + +P +P ++ ++ LL R Sbjct: 997 AVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMP--RDSVSILQKLLTR 1054 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYWPLI--RCMSPPEL 339 +P R+GS T A +I PFF +I W I + + PP L Sbjct: 1055 EPDQRLGSGPTDAQEIMSQPFFRNINWDDIYHKRVQPPFL 1094
>ORB6_SCHPO (O13310) Serine/threonine-protein kinase orb6 (EC 2.7.11.1)| Length = 469 Score = 71.2 bits (173), Expect = 2e-12 Identities = 39/101 (38%), Positives = 60/101 (59%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLI 468 G+ DWW+LG +++E L G PF +N +T+ I++ + LTFP+ I +S+EA+ L+ Sbjct: 308 GYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLM 367 Query: 467 HGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 L+ D R+G GA +I +HPFF I W IR + P Sbjct: 368 DRLM-TDSEHRLGRG-GAIEIMQHPFFTGIDWDHIRETAAP 406
>KPCI_PONPY (Q5R4K9) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| Length = 587 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/109 (33%), Positives = 60/109 (55%), Gaps = 11/109 (10%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF---------RGKNRKKTFYNILHKDLTFPS 504 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P Sbjct: 415 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 474 Query: 503 SIPVSLEAKQLIHGLLQRDPSSRIGSN--TGANDIKEHPFFEDIYWPLI 363 S+ S++A ++ L +DP R+G + TG DI+ HPFF ++ W ++ Sbjct: 475 SL--SVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMM 521
>KPCI_HUMAN (P41743) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota) Length = 587 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/109 (33%), Positives = 60/109 (55%), Gaps = 11/109 (10%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF---------RGKNRKKTFYNILHKDLTFPS 504 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P Sbjct: 415 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 474 Query: 503 SIPVSLEAKQLIHGLLQRDPSSRIGSN--TGANDIKEHPFFEDIYWPLI 363 S+ S++A ++ L +DP R+G + TG DI+ HPFF ++ W ++ Sbjct: 475 SL--SVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMM 521
>KPCI_MOUSE (Q62074) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) Length = 586 Score = 71.2 bits (173), Expect = 2e-12 Identities = 36/109 (33%), Positives = 60/109 (55%), Gaps = 11/109 (10%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF---------RGKNRKKTFYNILHKDLTFPS 504 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P Sbjct: 414 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 473 Query: 503 SIPVSLEAKQLIHGLLQRDPSSRIGSN--TGANDIKEHPFFEDIYWPLI 363 S+ S++A ++ L +DP R+G + TG DI+ HPFF ++ W ++ Sbjct: 474 SL--SVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMM 520
>ARBK1_RAT (P26817) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 71.2 bits (173), Expect = 2e-12 Identities = 41/110 (37%), Positives = 63/110 (57%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSL--EAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E + Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTMAVELPDSFSPELRS 423 Query: 473 LIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD + R+G GA +IKE PFF + W ++ PP L P Sbjct: 424 LLEGLLQRDVNRRLGCLGRGAQEIKESPFFRSLDWQMVFLQKYPPPLIPP 473
>ARBK1_MOUSE (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/110 (36%), Positives = 63/110 (57%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSL--EAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E + Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTMAVELPDSFSPELRS 423 Query: 473 LIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD + R+G GA ++KE PFF + W ++ PP L P Sbjct: 424 LLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPP 473
>ARBK1_MESAU (Q64682) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/110 (36%), Positives = 63/110 (57%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSL--EAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E + Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTMAVELPDSFSPELRS 423 Query: 473 LIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD + R+G GA ++KE PFF + W ++ PP L P Sbjct: 424 LLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPP 473
>ARBK1_BOVIN (P21146) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein-coupled receptor kinase 2) Length = 689 Score = 70.9 bits (172), Expect = 3e-12 Identities = 40/110 (36%), Positives = 63/110 (57%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSL--EAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E + Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTMAVELPDSFSPELRS 423 Query: 473 LIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD + R+G GA ++KE PFF + W ++ PP L P Sbjct: 424 LLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPP 473
>KPC2_DROME (P13677) Protein kinase C, eye isozyme (EC 2.7.11.13) (PKC)| (dPKC53E(EY)) (Protein INAC) (Inactivation no after-potential C protein) (Photoreceptor-specific PKC) (Eye-PKC) Length = 700 Score = 70.9 bits (172), Expect = 3e-12 Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Frame = -3 Query: 638 HTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGL 459 ++ A DWW+ G+LL+E + G+ PF G + F NI K FP S+EA +I Sbjct: 547 YSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHF--SVEAMDIITSF 604 Query: 458 LQRDPSSRIGSNTGA-NDIKEHPFFEDIYWPLIRC--MSPP 345 L + P++R+G+ A +I HPFF ++ W M PP Sbjct: 605 LTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPP 645
>MASTL_HUMAN (Q96GX5) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 879 Score = 70.9 bits (172), Expect = 3e-12 Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 1/110 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 ++ G H A+DWWALG+ L+E L G PF + ++ F NIL +D+ +P +S A Sbjct: 749 LLLGRAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNA 808 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVP 330 + + LL D + R G ++K HP F D+ W ++ + P + P Sbjct: 809 QSAVEILLTIDDTKR----AGMKELKRHPLFSDVDWENLQHQTMPFIPQP 854
>KPC1_TRIRE (Q99014) Protein kinase C-like (EC 2.7.11.13)| Length = 1139 Score = 70.9 bits (172), Expect = 3e-12 Identities = 36/100 (36%), Positives = 60/100 (60%), Gaps = 3/100 (3%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA G+L+Y+ML ++PFRG++ + + IL + +P +P ++ ++ LL R Sbjct: 994 AVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMP--RDSVSILQKLLTR 1051 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYWPLI--RCMSPPEL 339 +P R+GS T A ++ PFF +I W I + + PP L Sbjct: 1052 EPDQRLGSGPTDAQEVMSQPFFRNINWDDIYHKRVQPPFL 1091
>ARBK2_HUMAN (P35626) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 70.5 bits (171), Expect = 4e-12 Identities = 41/110 (37%), Positives = 64/110 (58%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E K Sbjct: 365 GTAYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTVNVELPDTFSPELKS 423 Query: 473 LIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD S R+G + G+ ++KEH FF+ + W + PP L P Sbjct: 424 LLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPP 473
>KAPCA_CANFA (Q8MJ44) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 349 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 208 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 265 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 266 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 301
>KPC1_COCHE (O42632) Protein kinase C-like (EC 2.7.11.13)| Length = 1174 Score = 70.5 bits (171), Expect = 4e-12 Identities = 33/87 (37%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA G+L+Y+ML ++PFRG++ + + IL + +P +P ++ ++ LL R Sbjct: 1029 AVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMP--RDSVSILQKLLTR 1086 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 +P R+GS T A +I H FF +I W Sbjct: 1087 EPEMRLGSGPTDAQEIMSHAFFRNINW 1113
>ROCK2_HUMAN (O75116) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 70.5 bits (171), Expect = 4e-12 Identities = 44/124 (35%), Positives = 67/124 (54%), Gaps = 4/124 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ LYEML G TPF + T+ I+ HK+ L FP +S AK LI L Sbjct: 276 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFL-T 334 Query: 449 DPSSRIGSNTGANDIKEHPFF--EDIYWPLIRCMSPPELDVPLKLIGKESQPKVKPEEGV 276 D R+G N G +I++HPFF + +W IR + P + I + ++ ++G Sbjct: 335 DREVRLGRN-GVEEIRQHPFFKNDQWHWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGD 393 Query: 275 IDTF 264 ++TF Sbjct: 394 VETF 397
>MASTL_MOUSE (Q8C0P0) Microtubule-associated serine/threonine-protein kinase-like| (EC 2.7.11.1) Length = 865 Score = 70.5 bits (171), Expect = 4e-12 Identities = 36/110 (32%), Positives = 59/110 (53%), Gaps = 1/110 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 ++ G H A+DWWALG+ L+E L G PF + ++ F NIL +D+ +P +S A Sbjct: 735 LLLGTAHGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDNA 794 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVP 330 + + LL D S R G ++K+HP F ++ W ++ + P + P Sbjct: 795 QSAMDMLLTIDDSKR----AGMRELKQHPLFSEVDWENLQHQTMPFVPQP 840
>KAPCA_SHEEP (Q9MZD9) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 302
>KAPCA_RAT (P27791) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 302
>KAPCA_PIG (P36887) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 302
>KAPCA_MOUSE (P05132) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 302
>KAPCA_HUMAN (P17612) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 302
>KAPCA_CRIGR (P25321) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 302
>KAPCA_BOVIN (P00517) cAMP-dependent protein kinase, alpha-catalytic subunit (EC| 2.7.11.11) (PKA C-alpha) Length = 350 Score = 70.5 bits (171), Expect = 4e-12 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 302
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 70.1 bits (170), Expect = 6e-12 Identities = 37/99 (37%), Positives = 59/99 (59%), Gaps = 5/99 (5%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFR---GKNRKKTFYNILHKDL-TFPSSIPVSLEAKQ 474 GH SA+DWW++G+L +E+L G +PF G+ ++ + K+ PSS S A+ Sbjct: 443 GHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSF--SANARD 500 Query: 473 LIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIR 360 + +L+++P R+G N A++IKEHPFF I W +R Sbjct: 501 FVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELR 539 Score = 30.0 bits (66), Expect = 6.3 Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 11/79 (13%) Frame = -3 Query: 638 HTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDL-------TFPSSI----PV 492 ++ A+D + LG LY ML G P+R H +L TF Sbjct: 796 YSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESA 855 Query: 491 SLEAKQLIHGLLQRDPSSR 435 S + L+ LQRDP+ R Sbjct: 856 SPAFRHLVSWCLQRDPADR 874
>MRCKG_HUMAN (Q6DT37) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 70.1 bits (170), Expect = 6e-12 Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 4/105 (3%) Frame = -3 Query: 647 GAGHTSA-IDWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIP-VSLEA 480 G GH DWW+LG+ YE+L+G TPF ++ +T+ I+ H+D L FP +P V A Sbjct: 249 GKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASA 308 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 + LI LL R R+G G +D + HPFFE + W + + P Sbjct: 309 QDLIRQLLCRQ-EERLGRG-GLDDFRNHPFFEGVDWERLASSTAP 351
>KGP1A_RABIT (O77676) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 6/110 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 +I GH + D+W+LGIL+YE+L G PF G + KT YNI+ + + FP I + Sbjct: 528 IILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKT-YNIILRGIDMIEFPKKI--AK 584 Query: 485 EAKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIR--CMSPP 345 A LI L + +PS R+G+ G DI++H +FE W +R ++PP Sbjct: 585 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 634
>KGP1A_HUMAN (Q13976) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 6/110 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 +I GH + D+W+LGIL+YE+L G PF G + KT YNI+ + + FP I + Sbjct: 528 IILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKT-YNIILRGIDMIEFPKKI--AK 584 Query: 485 EAKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIR--CMSPP 345 A LI L + +PS R+G+ G DI++H +FE W +R ++PP Sbjct: 585 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 634
>KGP1A_BOVIN (P00516) cGMP-dependent protein kinase 1, alpha isozyme (EC| 2.7.11.12) (CGK 1 alpha) (cGKI-alpha) Length = 670 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 6/110 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 +I GH + D+W+LGIL+YE+L G PF G + KT YNI+ + + FP I + Sbjct: 528 IILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKT-YNIILRGIDMIEFPKKI--AK 584 Query: 485 EAKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIR--CMSPP 345 A LI L + +PS R+G+ G DI++H +FE W +R ++PP Sbjct: 585 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 634
>KGP1B_MOUSE (Q9Z0Z0) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 6/110 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 +I GH + D+W+LGIL+YE+L G PF G + KT YNI+ + + FP I + Sbjct: 544 IILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKT-YNIILRGIDMIEFPKKI--AK 600 Query: 485 EAKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIR--CMSPP 345 A LI L + +PS R+G+ G DI++H +FE W +R ++PP Sbjct: 601 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 650
>KGP1B_HUMAN (P14619) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 6/110 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 +I GH + D+W+LGIL+YE+L G PF G + KT YNI+ + + FP I + Sbjct: 544 IILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKT-YNIILRGIDMIEFPKKI--AK 600 Query: 485 EAKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIR--CMSPP 345 A LI L + +PS R+G+ G DI++H +FE W +R ++PP Sbjct: 601 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 650
>KGP1B_BOVIN (P21136) cGMP-dependent protein kinase 1, beta isozyme (EC| 2.7.11.12) (cGK 1 beta) (cGKI-beta) Length = 686 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 6/110 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 +I GH + D+W+LGIL+YE+L G PF G + KT YNI+ + + FP I + Sbjct: 544 IILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKT-YNIILRGIDMIEFPKKI--AK 600 Query: 485 EAKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIR--CMSPP 345 A LI L + +PS R+G+ G DI++H +FE W +R ++PP Sbjct: 601 NAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPP 650
>KGP2_RAT (Q64595) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 70.1 bits (170), Expect = 6e-12 Identities = 47/135 (34%), Positives = 71/135 (52%), Gaps = 8/135 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 VI GH ++D+W+LGIL+YE+L G PF G ++ T+ IL + + FP I + Sbjct: 621 VILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKI--TRR 678 Query: 482 AKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMSPP-----ELDVPLKL 321 + LI L +++P+ R+G+ G NDIK+H + W ++ S P EL P Sbjct: 679 PEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGP--- 735 Query: 320 IGKESQPKVKPEEGV 276 I K PE+GV Sbjct: 736 IDHSYFDKYPPEKGV 750
>KGP2_MOUSE (Q61410) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 70.1 bits (170), Expect = 6e-12 Identities = 47/135 (34%), Positives = 71/135 (52%), Gaps = 8/135 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 VI GH ++D+W+LGIL+YE+L G PF G ++ T+ IL + + FP I + Sbjct: 621 VILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKI--TRR 678 Query: 482 AKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMSPP-----ELDVPLKL 321 + LI L +++P+ R+G+ G NDIK+H + W ++ S P EL P Sbjct: 679 PEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGP--- 735 Query: 320 IGKESQPKVKPEEGV 276 I K PE+GV Sbjct: 736 IDHSYFDKYPPEKGV 750
>MAST3_HUMAN (O60307) Microtubule-associated serine/threonine-protein kinase 3| (EC 2.7.11.1) Length = 1309 Score = 69.7 bits (169), Expect = 7e-12 Identities = 33/96 (34%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 VI G+ +DWWA+G++LYE L G PF G ++ F ++ ++ +P + +A Sbjct: 551 VIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADA 610 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 + LI LL++ P R+G+ G +++K+HPFF + W Sbjct: 611 QDLITRLLRQSPLDRLGTG-GTHEVKQHPFFLALDW 645
>KPC1_ASPNG (Q00078) Protein kinase C-like (EC 2.7.11.13)| Length = 1096 Score = 69.7 bits (169), Expect = 7e-12 Identities = 32/87 (36%), Positives = 54/87 (62%), Gaps = 1/87 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWWA G+L+Y+ML ++PFRG++ + + IL + +P +P ++ ++ LL R Sbjct: 951 AVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMP--RDSVSILQKLLTR 1008 Query: 449 DPSSRIGSN-TGANDIKEHPFFEDIYW 372 +P R+GS T A ++ H FF +I W Sbjct: 1009 EPELRLGSGPTDAQEVMSHAFFRNINW 1035
>KAPCG_HUMAN (P22612) cAMP-dependent protein kinase, gamma-catalytic subunit (EC| 2.7.11.11) (PKA C-gamma) Length = 350 Score = 69.7 bits (169), Expect = 7e-12 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS + S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKL--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G DIK H +F W Sbjct: 267 HLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSW 302
>DMPK_MOUSE (P54265) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 631 Score = 69.7 bits (169), Expect = 7e-12 Identities = 43/105 (40%), Positives = 59/105 (56%), Gaps = 4/105 (3%) Frame = -3 Query: 647 GAG-HTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFP-SSIPVSLEA 480 GAG + DWWALG+ YEM YG+TPF + +T+ I+H + L+ P + V EA Sbjct: 251 GAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEA 310 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 + LI GLL R+G GA D ++HPFF + W +R PP Sbjct: 311 QDLIRGLL-CPAEIRLGRG-GAGDFQKHPFFFGLDWEGLRDSVPP 353
>ARBK2_BOVIN (P26818) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 69.3 bits (168), Expect = 9e-12 Identities = 42/110 (38%), Positives = 62/110 (56%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E K Sbjct: 365 GTAYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTMNVELPDVFSPELKS 423 Query: 473 LIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD S R+G + G A ++K H FF I W + PP L P Sbjct: 424 LLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPP 473
>ARBK1_HUMAN (P25098) Beta-adrenergic receptor kinase 1 (EC 2.7.11.15)| (Beta-ARK-1) (G-protein coupled receptor kinase 2) Length = 689 Score = 69.3 bits (168), Expect = 9e-12 Identities = 40/110 (36%), Positives = 62/110 (56%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSL--EAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E Sbjct: 365 GVAYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTMAVELPDSFSPELHS 423 Query: 473 LIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD + R+G GA ++KE PFF + W ++ PP L P Sbjct: 424 LLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQRYPPPLIPP 473
>KGP2_HUMAN (Q13237) cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2)| (cGKII) (Type II cGMP-dependent protein kinase) Length = 762 Score = 69.3 bits (168), Expect = 9e-12 Identities = 46/132 (34%), Positives = 71/132 (53%), Gaps = 5/132 (3%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 VI GH ++D+W+LGIL+YE+L G PF G ++ T+ IL + + FP I + Sbjct: 621 VILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKI--TRR 678 Query: 482 AKQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMS-PPELDVPLK-LIGK 312 + LI L +++P+ R+G+ G NDIK+H + W ++ S P L LK I Sbjct: 679 PEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDH 738 Query: 311 ESQPKVKPEEGV 276 K PE+G+ Sbjct: 739 SYFDKYPPEKGM 750
>KPCI_BRARE (Q90XF2) Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota)| (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (Heart and soul protein) Length = 588 Score = 69.3 bits (168), Expect = 9e-12 Identities = 36/109 (33%), Positives = 59/109 (54%), Gaps = 11/109 (10%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF---------RGKNRKKTFYNILHKDLTFPS 504 ++ G + ++DWWALG+L++EM+ GR+PF F IL K + P Sbjct: 416 ILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPR 475 Query: 503 SIPVSLEAKQLIHGLLQRDPSSRIGSN--TGANDIKEHPFFEDIYWPLI 363 S+ S++A ++ G L ++ R+G + TG DI HPFF ++ W L+ Sbjct: 476 SL--SVKAASVLKGFLNKESKERLGCHPQTGFADIMAHPFFRNVDWDLM 522
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 69.3 bits (168), Expect = 9e-12 Identities = 34/89 (38%), Positives = 50/89 (56%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHG 462 GH+ +D W+ G+++Y +L G+ PF+ K K + I +FPS++ +S EAK LI Sbjct: 216 GHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISS 275 Query: 461 LLQRDPSSRIGSNTGANDIKEHPFFEDIY 375 LL DPS R +DI +H FF Y Sbjct: 276 LLTHDPSIR----PSIDDIVDHEFFHTGY 300
>KPC1_CAEEL (P34722) Protein kinase C-like 1 (EC 2.7.11.13) (PKC)| (Tetradecanoyl phorbol acetate resistant protein 1) Length = 704 Score = 69.3 bits (168), Expect = 9e-12 Identities = 34/96 (35%), Positives = 58/96 (60%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G + A+D+W+ G+L+YEML G++PF G+ + F +IL++ FP +I S EA Sbjct: 546 IIKGQLYNEAVDFWSFGVLMYEMLVGQSPFHGEGEDELFDSILNERPYFPKTI--SKEAA 603 Query: 476 QLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIYW 372 + + L R+P++R+G I++H FF + W Sbjct: 604 KCLSALFDRNPNTRLGMPECPDGPIRQHCFFRGVDW 639
>KDC2_DROME (P16912) Protein kinase DC2 (EC 2.7.11.1)| Length = 583 Score = 69.3 bits (168), Expect = 9e-12 Identities = 37/97 (38%), Positives = 55/97 (56%), Gaps = 2/97 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSI-PVSLEA 480 +I GH A+DWWALG+L+YEML G PF + + IL + + + P+ A Sbjct: 440 IIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPI---A 496 Query: 479 KQLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 K LI LL D + R+G+ GA+D+K H +F+ + W Sbjct: 497 KDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNW 533
>PDPK1_DROME (Q9W0V1) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (dPDK-1) (Serine/threonine-protein kinase 61C) (dSTPK61) Length = 836 Score = 68.9 bits (167), Expect = 1e-11 Identities = 38/102 (37%), Positives = 53/102 (51%), Gaps = 3/102 (2%) Frame = -3 Query: 635 TSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLL 456 T A D WALG ++Y+M+ G PFRG N F IL + FP +A+ L+ LL Sbjct: 488 TPAADLWALGCIVYQMIAGLPPFRGSNDYVIFKEILDCAVDFPQGF--DKDAEDLVRKLL 545 Query: 455 QRDPSSRIGSNTG---ANDIKEHPFFEDIYWPLIRCMSPPEL 339 + DP R+G+ I+ HPFF I W +R +PP + Sbjct: 546 RVDPRDRLGAQDEFGYYESIRAHPFFAGIDWQTLRQQTPPPI 587
>MAST2_MOUSE (Q60592) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1734 Score = 68.9 bits (167), Expect = 1e-11 Identities = 33/96 (34%), Positives = 57/96 (59%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 VI G+ +DWWA+GI+LYE L G PF G ++ F ++ ++ +P + +A Sbjct: 637 VILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDDALPPDA 696 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 + L LL ++P R+G+++ A ++K+HPFF + W Sbjct: 697 QDLTSKLLHQNPLERLGTSS-AYEVKQHPFFMGLDW 731
>KPC3_CAEEL (Q19266) Protein kinase C-like 3 (EC 2.7.11.13) (Atypical protein| kinase C-3) (aPKC3) Length = 597 Score = 68.9 bits (167), Expect = 1e-11 Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 15/119 (12%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF--------RGKNRKKTFYNILHKDLTFPSS 501 ++ G + ++DWWALG+L++EM+ GR+PF F IL + + P S Sbjct: 423 ILRGDEYGFSVDWWALGVLMFEMMAGRSPFDIVGMQNSEENTEDYLFQIILERQIRIPRS 482 Query: 500 IPVSLEAKQLIHGLLQRDPSSRIGS----NTGANDIKEHPFFED-IYWPLI--RCMSPP 345 + S+ A ++ G L +DP+ R+G N G D+KEH FF I W + + ++PP Sbjct: 483 L--SVRASGILKGFLNKDPTERLGCKLDINEGLRDMKEHQFFRGFIDWEALEQKAVAPP 539
>ROCK2_MOUSE (P70336) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/124 (35%), Positives = 67/124 (54%), Gaps = 4/124 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ L+EML G TPF + T+ I+ HK+ L FP +S AK LI L Sbjct: 276 DWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFL-T 334 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIY--WPLIRCMSPPELDVPLKLIGKESQPKVKPEEGV 276 D R+G N G +IK+HPFF++ W IR + P + I + ++ ++G Sbjct: 335 DREVRLGRN-GVEEIKQHPFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGD 393 Query: 275 IDTF 264 ++TF Sbjct: 394 VETF 397
>ROCK2_BOVIN (Q28021) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) Length = 1388 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/124 (35%), Positives = 67/124 (54%), Gaps = 4/124 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ L+EML G TPF + T+ I+ HK+ L FP +S AK LI L Sbjct: 276 DWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFL-T 334 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIY--WPLIRCMSPPELDVPLKLIGKESQPKVKPEEGV 276 D R+G N G +IK+HPFF++ W IR + P + I + ++ ++G Sbjct: 335 DREVRLGRN-GVEEIKQHPFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGD 393 Query: 275 IDTF 264 ++TF Sbjct: 394 VETF 397
>MAST2_HUMAN (Q6P0Q8) Microtubule-associated serine/threonine-protein kinase 2| (EC 2.7.11.1) Length = 1798 Score = 68.9 bits (167), Expect = 1e-11 Identities = 33/96 (34%), Positives = 56/96 (58%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFP-SSIPVSLEA 480 VI G+ +DWWA+GI+LYE L G PF G ++ F ++ ++ +P + +A Sbjct: 696 VILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDEALPPDA 755 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 + L LL ++P R+G+ + A ++K+HPFF + W Sbjct: 756 QDLTSKLLHQNPLERLGTGS-AYEVKQHPFFTGLDW 790
>CBK1_DEBHA (Q6BLJ9) Serine/threonine-protein kinase CBK1 (EC 2.7.11.1)| Length = 716 Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 2/101 (1%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLI 468 G+ DWW+LG +++E L G PF + +T+ IL+ + L P I +S E++ LI Sbjct: 549 GYGQECDWWSLGAIMFECLIGWPPFCSETPHETYRKILNWQETLQIPDDIHLSPESEDLI 608 Query: 467 HGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 LL + +R+G GA+++K HPFF + W IR + P Sbjct: 609 RKLL-TNAENRLGRYNGADELKLHPFFRGVDWDTIRKVDAP 648
>ARBK2_RAT (P26819) Beta-adrenergic receptor kinase 2 (EC 2.7.11.15)| (Beta-ARK-2) (G-protein-coupled receptor kinase 3) Length = 688 Score = 68.6 bits (166), Expect = 2e-11 Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 4/110 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQ 474 G + S+ DW++LG +L+++L G +PFR +++ K + I LT +P S E + Sbjct: 365 GTCYDSSADWFSLGCMLFKLLRGHSPFR-QHKTKDKHEIDRMTLTVNVQLPDAFSPELRS 423 Query: 473 LIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLIRCMS-PPELDVP 330 L+ GLLQRD S R+G GA ++KEH FF+ I W + PP L P Sbjct: 424 LLEGLLQRDVSQRLGCYGGGARELKEHIFFKGIDWQYVYLRKYPPPLIPP 473
>KAPC_CAEEL (P21137) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 404 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/107 (37%), Positives = 56/107 (52%), Gaps = 3/107 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S E K Sbjct: 247 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHF--SNELK 304 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYWPLI--RCMSPP 345 L+ LLQ D + R G+ G DIK H +F W I + ++PP Sbjct: 305 DLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITPP 351
>KAPB2_BOVIN (P24256) cAMP-dependent protein kinase, beta-2-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-2) Length = 397 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 256 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 313 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G +DIK H +F W Sbjct: 314 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 349
>MRCKG_MOUSE (Q80UW5) Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1)| (CDC42-binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma Length = 1551 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/105 (38%), Positives = 60/105 (57%), Gaps = 4/105 (3%) Frame = -3 Query: 647 GAGHTSA-IDWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSI-PVSLEA 480 G GH DWW+LG+ YE+L+G TPF ++ +T+ I+ H+D L FP+ + V A Sbjct: 249 GKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPADVTDVPASA 308 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 + LI LL R R+G G +D ++HPFFE + W + + P Sbjct: 309 QDLIRQLLCRQ-EERLGRG-GLDDFRKHPFFEGVDWERLATSTAP 351
>KAPCB_RAT (P68182) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G +DIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 302
>KAPCB_PIG (P05383) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G +DIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 302
>KAPCB_MOUSE (P68181) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G +DIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 302
>KAPCB_HUMAN (P22694) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G +DIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 302
>KAPCB_CRIGR (P68180) cAMP-dependent protein kinase, beta-catalytic subunit (EC| 2.7.11.11) (PKA C-beta) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G +DIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 302
>KAPB1_BOVIN (P05131) cAMP-dependent protein kinase, beta-1-catalytic subunit| (EC 2.7.11.11) (PKA C-beta-1) Length = 350 Score = 68.2 bits (165), Expect = 2e-11 Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS S + K Sbjct: 209 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF--SSDLK 266 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G +DIK H +F W Sbjct: 267 DLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDW 302
>LATS1_HUMAN (O95835) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) (h-warts) Length = 1130 Score = 67.8 bits (164), Expect = 3e-11 Identities = 37/95 (38%), Positives = 55/95 (57%), Gaps = 2/95 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 V+ G+T DWW++G++L+EML G+ PF + +T +++ L P +S E Sbjct: 921 VLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPE 980 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDI 378 A LI L R P R+G N GA++IK HPFF+ I Sbjct: 981 ASDLIIKLC-RGPEDRLGKN-GADEIKAHPFFKTI 1013
>ROCK1_RABIT (O77819) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (cAMP-dependent protein kinase ROCK-I) (CePKA) (Corneal epithelial Rho-associated-Ser/Thr kinase 1) (HEB Length = 1354 Score = 67.4 bits (163), Expect = 4e-11 Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ LYEML G TPF + T+ I+ HK+ LTFP +S EAK LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYW 372 D R+G N G +IK H FF++ W Sbjct: 319 DREVRLGRN-GVEEIKRHLFFKNDQW 343
>ROCK1_MOUSE (P70335) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 67.4 bits (163), Expect = 4e-11 Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ LYEML G TPF + T+ I+ HK+ LTFP +S EAK LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYW 372 D R+G N G +IK H FF++ W Sbjct: 319 DREVRLGRN-GVEEIKRHLFFKNDQW 343
>ROCK1_HUMAN (Q13464) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen) Length = 1354 Score = 67.4 bits (163), Expect = 4e-11 Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ LYEML G TPF + T+ I+ HK+ LTFP +S EAK LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYW 372 D R+G N G +IK H FF++ W Sbjct: 319 DREVRLGRN-GVEEIKRHLFFKNDQW 343
>ROCK1_RAT (Q63644) Rho-associated protein kinase 1 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (p150 RhoA-binding kinase ROK beta) (Liver regeneration-related protein LRRG199) Length = 1369 Score = 67.4 bits (163), Expect = 4e-11 Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ LYEML G TPF + T+ I+ HK+ LTFP +S EAK LI L Sbjct: 260 DWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFL-T 318 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYW 372 D R+G N G +IK H FF++ W Sbjct: 319 DREVRLGRN-GVEEIKRHLFFKNDQW 343
>KGP25_DROME (P32023) cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 (EC| 2.7.11.12) (CGK) (Foraging protein) Length = 934 Score = 67.0 bits (162), Expect = 5e-11 Identities = 40/118 (33%), Positives = 66/118 (55%), Gaps = 5/118 (4%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 VI GH + D+W+LG+L++E+L G PF G + +T YNI+ K + FP +I + Sbjct: 792 VILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRT-YNIILKGIDAIEFPRNI--TR 848 Query: 485 EAKQLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIY-WPLIRCMSPPELDVPLKLI 318 A LI L + +P+ R+G G ++I++H +F+ Y W L C P + +K + Sbjct: 849 NASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSV 906
>KGP24_DROME (Q03043) cGMP-dependent protein kinase, isozyme 2 forms| cD4/T1/T3A/T3B (EC 2.7.11.12) (CGK) (Foraging protein) Length = 1088 Score = 67.0 bits (162), Expect = 5e-11 Identities = 40/118 (33%), Positives = 66/118 (55%), Gaps = 5/118 (4%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 VI GH + D+W+LG+L++E+L G PF G + +T YNI+ K + FP +I + Sbjct: 946 VILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRT-YNIILKGIDAIEFPRNI--TR 1002 Query: 485 EAKQLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIY-WPLIRCMSPPELDVPLKLI 318 A LI L + +P+ R+G G ++I++H +F+ Y W L C P + +K + Sbjct: 1003 NASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSV 1060
>GRK6_MOUSE (O70293) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 67.0 bits (162), Expect = 5e-11 Identities = 37/96 (38%), Positives = 56/96 (58%), Gaps = 3/96 (3%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF--RGKNRKKTFYNILHKDLTFPSSIPVSLE 483 V+ +T + DWWALG LLYEM+ G++PF R K K+ L K++ + S + Sbjct: 356 VVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQ 415 Query: 482 AKQLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDI 378 A+ L LL +DP+ R+G GA ++KEHP F+ + Sbjct: 416 ARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKL 451
>DMPK_HUMAN (Q09013) Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy| protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK) Length = 639 Score = 66.6 bits (161), Expect = 6e-11 Identities = 39/96 (40%), Positives = 53/96 (55%), Gaps = 3/96 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFP-SSIPVSLEAKQLIHGLLQ 453 DWWALG+ YEM YG+TPF + +T+ I+H + L+ P V EA+ I LL Sbjct: 270 DWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLL- 328 Query: 452 RDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 P +R+G GA D + HPFF + W +R PP Sbjct: 329 CPPETRLGRG-GAGDFRTHPFFFGLDWDGLRDSVPP 363
>GRK6_HUMAN (P43250) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/96 (39%), Positives = 56/96 (58%), Gaps = 3/96 (3%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF--RGKNRKKTFYNILHKDLTFPSSIPVSLE 483 V+ +T + DWWALG LLYEM+ G++PF R K K+ L K++ S S + Sbjct: 356 VVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQ 415 Query: 482 AKQLIHGLLQRDPSSRIGSNTG-ANDIKEHPFFEDI 378 A+ L LL +DP+ R+G G A ++KEHP F+ + Sbjct: 416 ARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKL 451
>PDPK1_RAT (O55173) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (Protein kinase B kinase) (PkB kinase) Length = 559 Score = 65.9 bits (159), Expect = 1e-10 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++T + D WALG ++Y+++ G PFR N F I+ + FP +A+ Sbjct: 256 LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKF--FPKAR 313 Query: 476 QLIHGLLQRDPSSRIGSN--TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQ 303 L+ LL D + R+G G +K HPFFE I W + +PP+L L + ++ + Sbjct: 314 DLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESITWENLHQQTPPKLTAYLPAMSEDDE 373
>KGP1_DROME (Q03042) cGMP-dependent protein kinase, isozyme 1 (EC 2.7.11.12)| (CGK) Length = 768 Score = 65.9 bits (159), Expect = 1e-10 Identities = 41/99 (41%), Positives = 56/99 (56%), Gaps = 4/99 (4%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKD---LTFPSSIPVSL 486 +I GH A+D+WALGIL++E+L G PF + +T YN++ K + FP I S Sbjct: 627 IILNKGHDRAVDYWALGILIHELLNGTPPFSAPDPMQT-YNLILKGIDMIAFPKHI--SR 683 Query: 485 EAKQLIHGLLQRDPSSRIGSNTGA-NDIKEHPFFEDIYW 372 A QLI L + PS R+G TG DIK+H +F W Sbjct: 684 WAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWFLGFDW 722
>KAPC_DROME (P12370) cAMP-dependent protein kinase catalytic subunit (EC| 2.7.11.11) (PKA C) Length = 352 Score = 65.9 bits (159), Expect = 1e-10 Identities = 36/96 (37%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G+ A+DWWALG+L+YEM G PF + + I+ + FPS L K Sbjct: 211 IILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDL--K 268 Query: 476 QLIHGLLQRDPSSRIGS-NTGANDIKEHPFFEDIYW 372 L+ LLQ D + R G+ G NDIK +F W Sbjct: 269 DLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDW 304
>RK_BOVIN (P28327) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 561 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/111 (32%), Positives = 60/111 (54%), Gaps = 7/111 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGK----NRKKTFYNILHKDLTFPSSIPVS 489 ++ G + ++D++ALG+ LYEM+ R PFR + K+ +L + +T+P S Sbjct: 360 LLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKF--S 417 Query: 488 LEAKQLIHGLLQRDPSSRIGSNTGAND-IKEHPFFEDIYWPLIRC--MSPP 345 +K LLQ+DP R+G G+ D ++ HP F DI W + ++PP Sbjct: 418 PASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPP 468
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 1/124 (0%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 V+ GHT + DWW+ G+L+ GK+RK+T IL L P + S EA+ Sbjct: 233 VVNRQGHTHSADWWSYGVLM-----------GKDRKETMTLILKAKLGMPQFL--STEAQ 279 Query: 476 QLIHGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQP 300 L+ L +R+P++R+GS GA +IK H F+ I W KL +E +P Sbjct: 280 SLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWN--------------KLYRREIKP 325 Query: 299 KVKP 288 KP Sbjct: 326 PFKP 329 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/95 (33%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHK------DLTFPSSIP 495 V+ G+ D W+LGILLY ML G TPF T IL + L+ + Sbjct: 574 VLKRQGYDEGCDIWSLGILLYTMLAGYTPF-ANGPSDTPEEILTRIGSGKFTLSGGNWNT 632 Query: 494 VSLEAKQLIHGLLQRDPSSRIGSNTGANDIKEHPF 390 VS AK L+ +L DP R+ A + +HP+ Sbjct: 633 VSETAKDLVSKMLHVDPHQRL----TAKQVLQHPW 663
>LATS1_MOUSE (Q8BYR2) Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large| tumor suppressor homolog 1) (WARTS protein kinase) Length = 1129 Score = 65.5 bits (158), Expect = 1e-10 Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 2/95 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNIL--HKDLTFPSSIPVSLE 483 V+ G+T DWW++G++L EML G+ PF + +T ++ L P +S E Sbjct: 920 VLLRTGYTQLCDWWSVGVILCEMLVGQPPFLAQTPLETQMKVIIWQTSLHIPPQAKLSPE 979 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDI 378 A LI L R P R+G N GA++IK HPFF+ I Sbjct: 980 ASDLIIKLC-RGPEDRLGKN-GADEIKAHPFFKTI 1012
>PDPK1_HUMAN (O15530) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (hPDK1) Length = 556 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++T + D WALG ++Y+++ G PFR N F I+ + FP +A+ Sbjct: 253 LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKF--FPKAR 310 Query: 476 QLIHGLLQRDPSSRIGSN--TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQ 303 L+ LL D + R+G G +K HPFFE + W + +PP+L L + ++ + Sbjct: 311 DLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDE 370
>KAPC_ENCCU (Q8SRK8) Probable cAMP-dependent protein kinase catalytic subunit| (EC 2.7.11.11) Length = 322 Score = 65.5 bits (158), Expect = 1e-10 Identities = 38/102 (37%), Positives = 59/102 (57%), Gaps = 2/102 (1%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A D+W LG+++YEML G PF + ++ IL ++ FP VS A+ LI GLL + Sbjct: 184 ASDYWGLGVMIYEMLCGDPPFYDSSADAIYHKILESNVVFPHY--VSPVARCLITGLLDK 241 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIYWPLI--RCMSPPELDVP 330 + ++R+G+ G +I HPFF+ I W + R + PP + P Sbjct: 242 NRATRLGTK-GICEIMGHPFFKGIDWHEVESRRIEPPFIPNP 282
>PDPK1_CAEEL (Q9Y1J3) 3-phophoinositide-dependent protein kinase 1 (EC 2.7.11.1)| (Pdk-class protein kinase protein 1) Length = 636 Score = 65.5 bits (158), Expect = 1e-10 Identities = 41/120 (34%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQRDP 444 D W LG +L++ L G+ PFR N+ I D +FP P EA ++I +L RDP Sbjct: 292 DIWGLGCILFQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPE--EASEIIAKILVRDP 349 Query: 443 SSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELD--VPLKLIGKESQPKVKPEEGVID 270 S+RI S ++ H FFE++ W I + PP L +P E + P E +D Sbjct: 350 STRITS----QELMAHKFFENVDWVNIANIKPPVLHAYIPATFGEPEYYSNIGPVEPGLD 405
>PDPK1_MOUSE (Q9Z2A0) 3-phosphoinositide-dependent protein kinase 1 (EC| 2.7.11.1) (mPDK1) Length = 559 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 ++T + D WALG ++Y+++ G PFR N F I+ + FP +A+ Sbjct: 256 LLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYHFPEKF--FPKAR 313 Query: 476 QLIHGLLQRDPSSRIGSN--TGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLIGKESQ 303 L+ LL D + R+G G +K HPFFE I W + +PP+L L + ++ + Sbjct: 314 DLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFETITWENLHQQTPPKLTAYLPAMSEDDE 373
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 64.7 bits (156), Expect = 2e-10 Identities = 31/75 (41%), Positives = 45/75 (60%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G H +D W +G+L YE++ G PF + +T+ I+ DL FPSS+P L AK Sbjct: 247 MIEGRMHNEMVDLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSMP--LGAK 304 Query: 476 QLIHGLLQRDPSSRI 432 LI LL+ +PS R+ Sbjct: 305 DLISKLLKHNPSQRL 319
>PKD1_DICDI (P34100) Developmentally-regulated protein kinase 1 (EC 2.7.11.1)| (Fragment) Length = 416 Score = 64.7 bits (156), Expect = 2e-10 Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 5/113 (4%) Frame = -3 Query: 641 GHTSAIDWWALGILLYEMLYGRTPFRGK-----NRKKTFYNILHKDLTFPSSIPVSLEAK 477 GH +DWWALG+++YE++ G+ PF NRK F L F +S +S E K Sbjct: 210 GHGKPVDWWALGVVVYELVTGKLPFSNSKESLLNRKADF------QLIFQNSY-LSDEIK 262 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPPELDVPLKLI 318 I LL DPS R+G+ + I+ H +F DI W + S ++D PL + Sbjct: 263 DFIFQLLSVDPSKRLGTFDSCS-IRNHKWFSDINW--LHLESKYQIDGPLSTL 312
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/95 (40%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Frame = -3 Query: 647 GAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLEAKQ 474 G + S DW++ G +LY++L G +PFR +++ K I LT +P SLE K Sbjct: 366 GTSYDSCADWFSFGCMLYKLLKGHSPFR-QHKTKDKLEIDKMTLTMNVELPESFSLELKN 424 Query: 473 LIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIYW 372 L+ LLQRD S R+G GA+++K H FF I W Sbjct: 425 LLEMLLQRDVSKRLGCMGNGADEVKMHNFFCGIDW 459
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/91 (37%), Positives = 52/91 (57%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I + +D WALG+L YE+L G PF ++++ T+ IL ++L FP V EA+ Sbjct: 277 LIRSREYNEKVDVWALGVLTYELLVGSPPFEEESKELTYKRILKRNLIFPDH--VDTEAR 334 Query: 476 QLIHGLLQRDPSSRIGSNTGANDIKEHPFFE 384 LI LL+ DP RI ++K+HP+ E Sbjct: 335 HLISRLLEYDPGDRI----PLKEVKKHPWIE 361
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 63.9 bits (154), Expect = 4e-10 Identities = 41/115 (35%), Positives = 62/115 (53%), Gaps = 6/115 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH---KDLTFPSSIPVSL 486 +I +T + DWW LG L+YEM+ G +PFR K ++K L K+ T S S Sbjct: 356 IINHEKYTFSPDWWGLGCLIYEMIAGHSPFR-KYKEKVNREELERRVKNETEEYSERFSE 414 Query: 485 EAKQLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIYWPLIRC--MSPPELDVP 330 +AK + LL +DPS R+G G + +K+HP F+DI + + + PP + P Sbjct: 415 DAKSICSMLLIKDPSKRLGCQRDGVSAVKQHPIFKDINFSRLEANMLDPPFIPDP 469
>LATS2_HUMAN (Q9NRM7) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase) Length = 1088 Score = 63.9 bits (154), Expect = 4e-10 Identities = 35/95 (36%), Positives = 54/95 (56%), Gaps = 2/95 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 V+ G+T DWW++G++L+EML G+ PF +T +++ L P+ + +S E Sbjct: 884 VLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPE 943 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDI 378 A+ LI L R+G N GA+D+K HPFF I Sbjct: 944 ARDLITKLC-CSADHRLGRN-GADDLKAHPFFSAI 976
>GRK6_RAT (P97711) G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK6) Length = 576 Score = 63.9 bits (154), Expect = 4e-10 Identities = 36/96 (37%), Positives = 55/96 (57%), Gaps = 3/96 (3%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPF--RGKNRKKTFYNILHKDLTFPSSIPVSLE 483 V+ +T + DWWALG LLYEM+ G++PF R K K+ L K++ + S + Sbjct: 356 VVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSPQ 415 Query: 482 AKQLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDI 378 A+ L L +DP+ R+G GA ++KEHP F+ + Sbjct: 416 ARSLCSQLPNKDPAERLGCRGGGAREVKEHPLFKKL 451
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/110 (36%), Positives = 61/110 (55%), Gaps = 6/110 (5%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH---KDLTFPSSIPVSL 486 +I+ +T + DWW LG L+YEM+ G +PFR K ++K + K T S S Sbjct: 356 IISHEKYTFSPDWWGLGCLIYEMIAGHSPFR-KYKEKVNREEMERRVKTETEEYSERFSE 414 Query: 485 EAKQLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDIYWPLIRC--MSPP 345 AK + LL +DPS R+G + GA+ +K+HP F+DI + + + PP Sbjct: 415 NAKSICSMLLTKDPSKRLGCQSDGASAVKQHPIFKDINFSRLEANMLDPP 464
>COT1_NEUCR (P38679) Serine/threonine-protein kinase cot-1 (EC 2.7.11.1)| (Colonial temperature-sensitive 1) Length = 598 Score = 63.5 bits (153), Expect = 5e-10 Identities = 34/106 (32%), Positives = 60/106 (56%), Gaps = 2/106 (1%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 + TG G++ DWW+LG +++E L G PF ++ T+ I++ L FP I + ++ Sbjct: 429 IFTGHGYSFDCDWWSLGTIMFECLVGWPPFCAEDSHDTYRKIVNWRHSLYFPDDITLGVD 488 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 A+ LI L+ + +R+G GA++IK H FF + + +R + P Sbjct: 489 AENLIRSLI-CNTENRLGRG-GAHEIKSHAFFRGVEFDSLRRIRAP 532
>GRK4_HUMAN (P32298) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) (ITI1) Length = 578 Score = 62.8 bits (151), Expect = 9e-10 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 3/96 (3%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLE 483 V+ +T + DWW LG L+YEM+ G +PF+ K + + K+ T S S + Sbjct: 357 VVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSED 416 Query: 482 AKQLIHGLLQRDPSSRIG-SNTGANDIKEHPFFEDI 378 AK + LL ++PS R+G GA +K+HP F+DI Sbjct: 417 AKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDI 452
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 62.8 bits (151), Expect = 9e-10 Identities = 29/75 (38%), Positives = 44/75 (58%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAK 477 +I G H +D W +G+L YE+L G PF + +T+ I+ DL FP+S+P A+ Sbjct: 244 MIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTG--AQ 301 Query: 476 QLIHGLLQRDPSSRI 432 LI LL+ +PS R+ Sbjct: 302 DLISKLLRHNPSERL 316
>LATS2_MOUSE (Q7TSJ6) Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large| tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) Length = 1042 Score = 62.8 bits (151), Expect = 9e-10 Identities = 34/95 (35%), Positives = 55/95 (57%), Gaps = 2/95 (2%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLT--FPSSIPVSLE 483 V+ G+T DWW++G++L+EML G+ PF +T +++ + T P+ + +S E Sbjct: 842 VLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWESTLHIPTQVRLSAE 901 Query: 482 AKQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDI 378 A+ LI L R+G + GA+D+K HPFF I Sbjct: 902 ARDLITKLCCA-ADCRLGRD-GADDLKAHPFFNTI 934
>RK_HUMAN (Q15835) Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G| protein-coupled receptor kinase 1) Length = 563 Score = 62.8 bits (151), Expect = 9e-10 Identities = 35/123 (28%), Positives = 62/123 (50%), Gaps = 5/123 (4%) Frame = -3 Query: 656 VITGAGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP--VSLE 483 ++ G + ++D++ALG+ LYEM+ R PFR + K + H+ ++ P P S Sbjct: 363 LLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFSQA 422 Query: 482 AKQLIHGLLQRDPSSRIGSNTGAND-IKEHPFFEDIYWPLIRC--MSPPELDVPLKLIGK 312 +K LL++DP R+G D ++ HP F+D+ W + + PP + + K Sbjct: 423 SKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVYAK 482 Query: 311 ESQ 303 + Q Sbjct: 483 DIQ 485
>PSK1_SCHPO (Q12706) Serine/threonine-protein kinase psk1 (EC 2.7.11.22)| Length = 436 Score = 62.8 bits (151), Expect = 9e-10 Identities = 32/109 (29%), Positives = 58/109 (53%), Gaps = 13/109 (11%) Frame = -3 Query: 629 AIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLLQR 450 A+DWW++GIL++++L G PF N K+ I P V+ +A+ +I+ L++ Sbjct: 269 AVDWWSMGILIFDLLTGSPPFTANNHKRIMEKITRAKPNIP--FYVTSDARDIINKFLKK 326 Query: 449 DPSSRIGSN---TGANDIKEHPFFEDIYW----------PLIRCMSPPE 342 +P R+G++ G + IK+H + I W P++ C++ PE Sbjct: 327 NPKQRLGADGPEKGYDAIKKHRIYRRIDWNKLEKRMLPPPIVPCITNPE 375
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 7/112 (6%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGK----NRKKTFYNILHKDLTFPSSIPVSLEAKQLIHGLL 456 D+W LG L+YEM+ G++PFRG+ R++ +L + + S S EAK + + LL Sbjct: 367 DYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSSKF--SEEAKSICNMLL 424 Query: 455 QRDPSSRIG-SNTGANDIKEHPFFEDIYWPLIRC--MSPPELDVPLKLIGKE 309 +D R+G GA ++K HPFF ++ + + + PP + P + K+ Sbjct: 425 TKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKD 476
>ROCK2_RAT (Q62868) Rho-associated protein kinase 2 (EC 2.7.11.1)| (Rho-associated, coiled-coil-containing protein kinase 2) (p164 ROCK-2) (RhoA-binding kinase 2) (p150 ROK-alpha) (ROKalpha) Length = 1379 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/124 (33%), Positives = 64/124 (51%), Gaps = 4/124 (3%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNIL-HKD-LTFPSSIPVSLEAKQLIHGLLQR 450 DWW++G+ L+EML G TPF + T+ I+ HK+ L FP +S AK LI L Sbjct: 267 DWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDTEISKHAKNLICAFL-T 325 Query: 449 DPSSRIGSNTGANDIKEHPFFEDIY--WPLIRCMSPPELDVPLKLIGKESQPKVKPEEGV 276 D R+G N G +IK FF++ W IR + P + I + ++ ++G Sbjct: 326 DREVRLGRN-GVEEIKSASFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDDKGD 384 Query: 275 IDTF 264 ++TF Sbjct: 385 VETF 388
>KS6C1_MOUSE (Q8BLK9) Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa| ribosomal protein S6 kinase) Length = 1056 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/93 (40%), Positives = 48/93 (51%), Gaps = 5/93 (5%) Frame = -3 Query: 635 TSAIDWWALGILLYEMLYGRTPFR----GKNRKKTFYNILHKDLTFPSSIPVSLEAKQLI 468 T A DWW+LG +L+E+L G+T G N H L P VS EA+ LI Sbjct: 969 TEACDWWSLGAVLFELLTGKTLVECHPAGIN--------THTTLNMPGC--VSEEARSLI 1018 Query: 467 HGLLQRDPSSRIGSN-TGANDIKEHPFFEDIYW 372 LLQ +P R+G+ G DIK HPFF + W Sbjct: 1019 QQLLQFNPMERLGAGVAGVEDIKSHPFFTPVDW 1051
>GRK7_SPETR (Q9Z2G7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 548 Score = 60.8 bits (146), Expect = 3e-09 Identities = 34/119 (28%), Positives = 62/119 (52%), Gaps = 7/119 (5%) Frame = -3 Query: 644 AGHTSAIDWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP-----VSLEA 480 A ++ +DW+A+G +YEM+ GRTPF+ K + ++ K+ T + + E Sbjct: 361 ASYSYPVDWFAMGCSIYEMVAGRTPFKDFKEKVSKEDL--KERTMKDEVAFHHENFTEET 418 Query: 479 KQLIHGLLQRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRC--MSPPELDVPLKLIGKE 309 K + L + P R+GS A+D ++HPFF+ + +P + + PP + P + K+ Sbjct: 419 KDICRLFLAKKPEQRLGSREKADDPRKHPFFQTVNFPRLEAGLVEPPFVPDPSVVYAKD 477
>RIM15_YEAST (P43565) Serine/threonine-protein kinase RIM15 (EC 2.7.11.1)| Length = 1770 Score = 60.8 bits (146), Expect = 3e-09 Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 7/91 (7%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNILHKDLTFPSSIP-------VSLEAKQLIH 465 DWW++G + +E+L G PF + F IL + +P ++ EAK LI Sbjct: 1170 DWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIE 1229 Query: 464 GLLQRDPSSRIGSNTGANDIKEHPFFEDIYW 372 LL DP+ R+G+ G +IK+HP+F+++ W Sbjct: 1230 KLLVVDPAKRLGAK-GIQEIKDHPYFKNVDW 1259
>CTRO_HUMAN (O14578) Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK)| (Rho-interacting, serine/threonine-protein kinase 21) Length = 2027 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/97 (38%), Positives = 51/97 (52%), Gaps = 4/97 (4%) Frame = -3 Query: 623 DWWALGILLYEMLYGRTPFRGKNRKKTFYNILH--KDLTFPSSIPVSLEAKQLIHGLL-- 456 DWW++G++ YEM+YGR+PF +TF NI++ + L FP VS + LI LL Sbjct: 285 DWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCG 344 Query: 455 QRDPSSRIGSNTGANDIKEHPFFEDIYWPLIRCMSPP 345 Q++ G + HPFF I W IR PP Sbjct: 345 QKERLKFEG-------LCCHPFFSKIDWNNIRNSPPP 374 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 101,052,005 Number of Sequences: 219361 Number of extensions: 2203231 Number of successful extensions: 6862 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6225 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6450 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6257125380 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
