ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal11h15 |
|---|---|
| Clone Library Name | barley_pub |
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 109 bits (272), Expect = 9e-24 Identities = 50/119 (42%), Positives = 74/119 (62%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 K+ADFG + +E Q ++ G GT +MAPE++ KPY RK DVYSFGI LWE+ +P Sbjct: 227 KVADFGTSCLETQC-REAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTALLP 285 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 + ++ + AV +N RP +P C A A+++++CW NP KRPD +V ++E D Sbjct: 286 FQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDFSNIVAVLEKYD 344
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 95.5 bits (236), Expect = 1e-19 Identities = 45/123 (36%), Positives = 70/123 (56%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG +R N GT +MAPEV+ P + CD YS+G+ LWE+ ++P Sbjct: 148 KICDFGASRFH--NHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVP 205 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL-- 338 + L V+ VV +N R IP CP +FA ++ +CW+ + KRP +++ ++E++ Sbjct: 206 FKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSN 265 Query: 337 DTS 329 DTS Sbjct: 266 DTS 268
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 94.7 bits (234), Expect = 2e-19 Identities = 42/118 (35%), Positives = 67/118 (56%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG +R N GT +MAPEV+ P + CD YS+G+ LWE+ ++P Sbjct: 148 KICDFGASRFH--NHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVP 205 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 + L V+ VV +N R IP CP +FA ++ +CW+ + KRP +++ ++E++ Sbjct: 206 FKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 94.4 bits (233), Expect = 3e-19 Identities = 41/119 (34%), Positives = 70/119 (58%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI+DFG++R++ + MT + G + YMAPEV G + K DVYS+G+ L+E+ D P Sbjct: 1445 KISDFGLSRLKKEQASQMTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEP 1504 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 D+ ++ +++ RP IP S + I+ +CWD NPD RP +++ ++ ++ Sbjct: 1505 QQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEME 1563
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 92.8 bits (229), Expect = 9e-19 Identities = 50/113 (44%), Positives = 68/113 (60%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KIADFG AR++ N MT GT + APEV+ G+ Y K DV+SFG+ +WE+ P Sbjct: 1502 KIADFGFARIKEDNTT-MTRC-GTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEP 1559 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + + +F VS ++ + RP IP CP FA +++KCW KRP M EVVQ Sbjct: 1560 FAECNFMKVSLDIL-EGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQ 1611 Score = 64.3 bits (155), Expect = 3e-10 Identities = 36/120 (30%), Positives = 67/120 (55%), Gaps = 8/120 (6%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGAT--GTLGYMAPEVLDGKPYNRK--CDVYSFGICLWEIYC 524 K++DFG+ +V+++ K T GT+ ++APE+L+ DVYSFGI LWE+ Sbjct: 923 KVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLT 982 Query: 523 CDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSA----FANIMRKCWDGNPDKRPDMDEVV 356 + PY ++ A ++ +V+ +RP I +A + +++++CW + RP E++ Sbjct: 983 REQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIM 1042
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 92.4 bits (228), Expect = 1e-18 Identities = 47/119 (39%), Positives = 68/119 (57%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG+AR E M+ A GT +MAPEV+ +++ DV+SFG+ LWE+ ++P Sbjct: 264 KITDFGLAR-EWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVP 321 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 Y + V+ V L IP CP FA +M CW +P +RPD ++Q +EAL+ Sbjct: 322 YRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALE 380
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 92.0 bits (227), Expect = 1e-18 Identities = 44/121 (36%), Positives = 69/121 (57%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG+AR + K A GT +MAPEV+ +++ DV+SFG+ LWE+ ++P Sbjct: 245 KITDFGLAREWHKTTK--MSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVP 302 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y ++ V+ V L IP CP FA ++ +CWD +P RPD +++ +E ++ Sbjct: 303 YREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQ 362 Query: 331 S 329 S Sbjct: 363 S 363
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 89.7 bits (221), Expect = 7e-18 Identities = 45/122 (36%), Positives = 69/122 (56%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG+AR E N + M+ A GT +M PEV+ Y++ DV+S+G+ LWE+ + P Sbjct: 287 KITDFGLAR-EMYNTQRMSAA-GTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETP 344 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 Y V+ V L IP+ CP + +M+ CW +P KRP E+++ +E++ Sbjct: 345 YKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIAC 404 Query: 331 SK 326 SK Sbjct: 405 SK 406
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 89.0 bits (219), Expect = 1e-17 Identities = 47/118 (39%), Positives = 66/118 (55%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 K+ DFG++R++A A GT +MAPEVL +P N K DVYSFG+ LWE+ P Sbjct: 691 KVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQP 750 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 + +L+ A V +AV + R +IPR A I+ CW P KRP ++ L+ L Sbjct: 751 WGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 86.7 bits (213), Expect = 6e-17 Identities = 38/112 (33%), Positives = 66/112 (58%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI+DFG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++P Sbjct: 284 KISDFGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 342 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 Y D+ + + V +L +P CP F ++R+CW+ P RP +++ Sbjct: 343 YKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL 394
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 86.7 bits (213), Expect = 6e-17 Identities = 38/112 (33%), Positives = 66/112 (58%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI+DFG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++P Sbjct: 251 KISDFGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 309 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 Y D+ + + V +L +P CP F ++R+CW+ P RP +++ Sbjct: 310 YKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQIL 361
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 85.9 bits (211), Expect = 1e-16 Identities = 44/119 (36%), Positives = 65/119 (54%), Gaps = 1/119 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG A MT G+ +MAPEV +G Y+ KCDV+S+GI LWE+ P Sbjct: 172 KICDFGTA---CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228 Query: 511 YPDLSF-ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 + ++ A VH RP + + P ++M +CW +P +RP M+E+V++M L Sbjct: 229 FDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 85.9 bits (211), Expect = 1e-16 Identities = 44/119 (36%), Positives = 65/119 (54%), Gaps = 1/119 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG A MT G+ +MAPEV +G Y+ KCDV+S+GI LWE+ P Sbjct: 172 KICDFGTA---CDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228 Query: 511 YPDLSF-ADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 + ++ A VH RP + + P ++M +CW +P +RP M+E+V++M L Sbjct: 229 FDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 85.9 bits (211), Expect = 1e-16 Identities = 38/112 (33%), Positives = 66/112 (58%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI+DFG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++P Sbjct: 284 KISDFGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 342 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 Y D+ + + V +L +P CP F ++R+CW+ P RP +++ Sbjct: 343 YKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFRQIL 394
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 85.1 bits (209), Expect = 2e-16 Identities = 48/121 (39%), Positives = 64/121 (52%), Gaps = 6/121 (4%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG+A + N DM G TL YMAPE + Y KCDVYSFGI LWE+ +P Sbjct: 149 KICDFGLATDMSNNKTDMQG---TLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMTRQLP 205 Query: 511 Y-----PDLSFADVSSAVVHQNLRPDIPRC-CPSAFANIMRKCWDGNPDKRPDMDEVVQL 350 Y P+ +A + + + L + R CP +M C D NP+KRP M E+ + Sbjct: 206 YSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKF 265 Query: 349 M 347 + Sbjct: 266 L 266
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 83.2 bits (204), Expect = 7e-16 Identities = 40/121 (33%), Positives = 64/121 (52%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG+AR + K A GT +MAPEV+ +++ DV+S+G+ LWE+ ++P Sbjct: 291 KITDFGLAREWHRTTK--MSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVP 348 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALDT 332 + + V+ V L IP CP FA +M CW+ +P RP ++ + ++ Sbjct: 349 FRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEE 408 Query: 331 S 329 S Sbjct: 409 S 409
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 82.8 bits (203), Expect = 9e-16 Identities = 40/119 (33%), Positives = 66/119 (55%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG+AR + K T GT +MAPEV+ +++ D++S+G+ LWE+ ++P Sbjct: 286 KITDFGLAREWHRTTKMSTA--GTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEVP 343 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 Y + V+ V L IP CP FA +M++CW +P RP +++ + A++ Sbjct: 344 YRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIE 402
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 81.6 bits (200), Expect = 2e-15 Identities = 37/116 (31%), Positives = 65/116 (56%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI+DFG ++ + M+ A GT+ +MAPEV+ +P + K D++SFG+ LWE+ ++P Sbjct: 294 KISDFGTSKELSDKSTKMSFA-GTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 352 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 Y D+ + + V +L +P CP F +M++ W P RP + + ++ Sbjct: 353 YKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLD 408
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 80.9 bits (198), Expect = 3e-15 Identities = 46/145 (31%), Positives = 75/145 (51%), Gaps = 1/145 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 K++DFG+A+ E + K + + + + APE L ++ K DV+SFG+ LWE++ Sbjct: 326 KVSDFGLAKAELR--KGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA 383 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 PYP +S +VS AV + R + P CP +M CW+ P +RP ++V+ + Sbjct: 384 PYPKMSLKEVSEAV-EKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKLGREL 442 Query: 334 TSKGGGMIPDGQSSGCLCFTRARGP 260 S G GQ + TR++ P Sbjct: 443 RSVGVAAPAGGQEAEGSAPTRSQDP 467
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 80.9 bits (198), Expect = 3e-15 Identities = 39/118 (33%), Positives = 58/118 (49%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFG A MT G+ +MAPEV +G Y KCD++S+ I LWE+ P Sbjct: 156 KICDFGTV---ADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQP 212 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 + + A +++ RP + CP ++M CW P+ RP M +V +M + Sbjct: 213 FKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEI 270
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 80.5 bits (197), Expect = 4e-15 Identities = 36/116 (31%), Positives = 65/116 (56%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI+DFG ++ + M+ A GT+ ++APEV+ +P + K D++SFG+ LWE+ ++P Sbjct: 294 KISDFGTSKELSDKSTKMSFA-GTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIP 352 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 Y D+ + + V +L +P CP F +M++ W P RP + + ++ Sbjct: 353 YKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHLD 408
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 79.3 bits (194), Expect = 1e-14 Identities = 46/145 (31%), Positives = 75/145 (51%), Gaps = 1/145 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM- 515 K++DFG+A+ E K + + + + APE L ++ K DV+SFG+ LWE++ Sbjct: 365 KVSDFGLAKAER---KGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA 421 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 PYP +S +VS AV + R + P CP + +M CW+ P +RP ++V+ + Sbjct: 422 PYPKMSLKEVSEAV-EKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGREL 480 Query: 334 TSKGGGMIPDGQSSGCLCFTRARGP 260 S G GQ + TR++ P Sbjct: 481 RSVGVSAPAGGQEAEGSAPTRSQDP 505
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 78.6 bits (192), Expect = 2e-14 Identities = 44/146 (30%), Positives = 78/146 (53%), Gaps = 11/146 (7%) Frame = -2 Query: 688 IADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEIYCCDM 515 +ADFG +R +++ + +MT G L +MAPEV Y K DV+S+ +CLWE+ ++ Sbjct: 602 VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEI 661 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME--- 344 P+ L A ++ + + ++RP I P ++++ + W+ P+ RP+ EVV+ +E Sbjct: 662 PFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRGWNACPEGRPEFSEVVRKLEECL 721 Query: 343 ------ALDTSKGGGMIPDGQSSGCL 284 + +S G + SS CL Sbjct: 722 CNVELMSPASSNSSGSLSPSSSSDCL 747
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 78.6 bits (192), Expect = 2e-14 Identities = 46/155 (29%), Positives = 78/155 (50%), Gaps = 12/155 (7%) Frame = -2 Query: 688 IADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEIYCCDM 515 +ADFG +R +++ + +MT G L +MAPEV Y K DV+S+ +CLWEI ++ Sbjct: 705 VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEI 764 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV------- 356 P+ L A ++ + + ++RP I P ++++ + W+ P+ RP+ EVV Sbjct: 765 PFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECL 824 Query: 355 ---QLMEALDTSKGGGMIPDGQSSGCLCFTRARGP 260 +LM ++ G + P S C GP Sbjct: 825 CNIELMSPASSNSSGSLSPSSSSD---CLVNRGGP 856
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 77.4 bits (189), Expect = 4e-14 Identities = 44/146 (30%), Positives = 77/146 (52%), Gaps = 11/146 (7%) Frame = -2 Query: 688 IADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDG-KPYNRKCDVYSFGICLWEIYCCDM 515 +ADFG +R +++ + +MT G L +MAPEV Y K DV+S+ +CLWE+ ++ Sbjct: 603 VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYSLCLWELLTGEI 662 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME--- 344 P+ L A ++ + + ++RP I P ++++ + W+ P+ RP+ EVV +E Sbjct: 663 PFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVVSKLEECL 722 Query: 343 ------ALDTSKGGGMIPDGQSSGCL 284 + +S G + SS CL Sbjct: 723 CNVELMSPASSNSSGSLSPSSSSDCL 748
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 75.9 bits (185), Expect = 1e-13 Identities = 48/122 (39%), Positives = 66/122 (54%), Gaps = 3/122 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR + G L +MAPE L + Y + DV+SFGI LWEI+ Sbjct: 625 KIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLG 684 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + ++ S ++ + R + P CPS +MR+CW P +RP QL+EA Sbjct: 685 GSPYPGIPVEELFS-LLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFK---QLVEA 740 Query: 340 LD 335 LD Sbjct: 741 LD 742
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 75.5 bits (184), Expect = 1e-13 Identities = 48/122 (39%), Positives = 65/122 (53%), Gaps = 3/122 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR + G L +MAPE L + Y + DV+SFGI LWEI+ Sbjct: 627 KIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLG 686 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + ++ S ++ + R D P CP +MR+CW P +RP QL+EA Sbjct: 687 GSPYPGIPVEELFS-LLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFK---QLVEA 742 Query: 340 LD 335 LD Sbjct: 743 LD 744
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 75.5 bits (184), Expect = 1e-13 Identities = 47/125 (37%), Positives = 62/125 (49%), Gaps = 3/125 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR G L +MAPE L K Y+ K DV+S+GI LWEI Sbjct: 571 KIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYG 630 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + A+ + R + P C +MR+CW N D RP E+V+ M+ Sbjct: 631 QQPYPTIMSAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDK 690 Query: 340 LDTSK 326 L +K Sbjct: 691 LLQTK 695
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 75.1 bits (183), Expect = 2e-13 Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 1/145 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-M 515 K++DFG+A+ E K + + + + APE L + K DV+SFG+ LWE++ Sbjct: 367 KVSDFGLAKAER---KGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRA 423 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 PYP +S +VS A V + R + P CP +M CW+ P +RP ++ + + Sbjct: 424 PYPKMSLKEVSEA-VEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLAREL 482 Query: 334 TSKGGGMIPDGQSSGCLCFTRARGP 260 S G GQ + R++ P Sbjct: 483 RSAGAPASVSGQDADGSTSPRSQEP 507
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 74.3 bits (181), Expect = 3e-13 Identities = 43/128 (33%), Positives = 66/128 (51%), Gaps = 3/128 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++P + + L +MAPE + K Y + DV+SFG+ LWEI+ Sbjct: 1052 KICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLG 1111 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + + + R P A +IM+ CW G+P RP ++V+++ Sbjct: 1112 ASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILG- 1170 Query: 340 LDTSKGGG 317 D +GGG Sbjct: 1171 -DLLQGGG 1177
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 74.3 bits (181), Expect = 3e-13 Identities = 43/128 (33%), Positives = 66/128 (51%), Gaps = 3/128 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++P + + L +MAPE + K Y + DV+SFG+ LWEI+ Sbjct: 1052 KICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLG 1111 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + + + R P A +IM+ CW G+P RP ++V+++ Sbjct: 1112 ASPYPGVQINEEFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILG- 1170 Query: 340 LDTSKGGG 317 D +GGG Sbjct: 1171 -DLLQGGG 1177
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 73.9 bits (180), Expect = 4e-13 Identities = 41/120 (34%), Positives = 63/120 (52%), Gaps = 2/120 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWEI M Sbjct: 264 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM 323 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Q E + Sbjct: 324 SPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 382
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 73.9 bits (180), Expect = 4e-13 Identities = 41/120 (34%), Positives = 63/120 (52%), Gaps = 2/120 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWEI M Sbjct: 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM 437 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Q E + Sbjct: 438 SPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 496
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 73.9 bits (180), Expect = 4e-13 Identities = 41/120 (34%), Positives = 63/120 (52%), Gaps = 2/120 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWEI M Sbjct: 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM 437 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Q E + Sbjct: 438 SPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 496
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 73.9 bits (180), Expect = 4e-13 Identities = 43/135 (31%), Positives = 71/135 (52%), Gaps = 17/135 (12%) Frame = -2 Query: 691 KIADFGVARVEAQNPK--DMTGATGTLGYMAPEVL-------------DGK--PYNRKCD 563 K+ADFG+++ + + + + T GT +MAPEV+ DGK Y K D Sbjct: 1151 KVADFGLSKTKDSSTRYSNQTWNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSD 1210 Query: 562 VYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPD 383 VYSFG+ +E+ D+P+P+ + +V + +RPD+P CP ++ CW+ +P Sbjct: 1211 VYSFGMVCYEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPL 1270 Query: 382 KRPDMDEVVQLMEAL 338 KRP + Q ++ L Sbjct: 1271 KRPSFAVICQKLKYL 1285
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 73.9 bits (180), Expect = 4e-13 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 792 KICDFGLAR-DIRNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGILLWELFSL 850 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P C P +IM+ CWD +P +RP ++VQL+E Sbjct: 851 GSSPYPGMPVDSKFYKMIKEGYRMFSPECSPPEMYDIMKSCWDADPLQRPTFKQIVQLIE 910
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 73.2 bits (178), Expect = 7e-13 Identities = 44/114 (38%), Positives = 64/114 (56%), Gaps = 3/114 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 K++DFG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY Sbjct: 329 KVSDFGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFG 383 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 +PYP + DV V + + D P CP+ +M+KCW +P RP ++ Sbjct: 384 RVPYPRIPLKDVVPR-VEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQL 436
>MET_RAT (P97523) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 73.2 bits (178), Expect = 7e-13 Identities = 43/123 (34%), Positives = 67/123 (54%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1220 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1279 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP A +M KCW + RP + E+V + Sbjct: 1280 RGAPPYPDVNTFDITIYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRI 1338 Query: 346 EAL 338 ++ Sbjct: 1339 SSI 1341
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 72.8 bits (177), Expect = 9e-13 Identities = 42/126 (33%), Positives = 62/126 (49%), Gaps = 3/126 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++P + + L +MAPE + K Y + DV+SFG+ LWEI+ Sbjct: 1052 KICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLG 1111 Query: 517 M-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + + + R P A IM CW G+P RP E+V+++ Sbjct: 1112 ASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGD 1171 Query: 340 LDTSKG 323 L +G Sbjct: 1172 LLQGRG 1177
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 72.8 bits (177), Expect = 9e-13 Identities = 47/122 (38%), Positives = 65/122 (53%), Gaps = 3/122 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KIADFG+AR + G L +MAPE L + Y + DV+SF I LWEI+ Sbjct: 624 KIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFTLG 683 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + ++ S ++ + R + P CPS +MR+CW P +RP QL+EA Sbjct: 684 GSPYPGIPVEELFS-LLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFK---QLVEA 739 Query: 340 LD 335 LD Sbjct: 740 LD 741
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 72.8 bits (177), Expect = 9e-13 Identities = 43/123 (34%), Positives = 66/123 (53%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1217 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1276 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP A +M KCW + RP E+V + Sbjct: 1277 RGAPPYPDVNTFDITIYLL-QGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRI 1335 Query: 346 EAL 338 ++ Sbjct: 1336 SSI 1338
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 72.4 bits (176), Expect = 1e-12 Identities = 44/123 (35%), Positives = 65/123 (52%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR+ N GA + + APE ++ + K DV+SFGI L EI Sbjct: 393 KIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR 452 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP +S +V A+ H P P CP NIM +CW P++RP + + +++ Sbjct: 453 IPYPGMSNPEVIRALEHGYRMPR-PDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDF 511 Query: 337 DTS 329 T+ Sbjct: 512 YTA 514
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 72.4 bits (176), Expect = 1e-12 Identities = 44/123 (35%), Positives = 65/123 (52%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+ARV N GA + + APE ++ + K DV+SFGI L EI Sbjct: 395 KIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR 454 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP +S +V A+ + R P CP NIM +CW P++RP + + +++ Sbjct: 455 IPYPGMSNPEVIRAL-ERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDF 513 Query: 337 DTS 329 T+ Sbjct: 514 YTA 516
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1219 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1278 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1279 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337 Query: 346 EAL 338 A+ Sbjct: 1338 SAI 1340
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1219 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1278 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1279 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337 Query: 346 EAL 338 A+ Sbjct: 1338 SAI 1340
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1219 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1278 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1279 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337 Query: 346 EAL 338 A+ Sbjct: 1338 SAI 1340
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1219 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1278 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1279 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337 Query: 346 EAL 338 A+ Sbjct: 1338 SAI 1340
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1219 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMT 1278 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1279 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337 Query: 346 EAL 338 A+ Sbjct: 1338 SAI 1340
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1220 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1279 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1280 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1338 Query: 346 EAL 338 A+ Sbjct: 1339 SAI 1341
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 72.0 bits (175), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1220 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1279 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1280 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1338 Query: 346 EAL 338 A+ Sbjct: 1339 SAI 1341
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 71.6 bits (174), Expect = 2e-12 Identities = 45/123 (36%), Positives = 67/123 (54%), Gaps = 3/123 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 K++DFG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY Sbjct: 329 KVSDFGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFG 383 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 +PYP + DV V + + D P CP A +M+ CW + RP ++ + +E Sbjct: 384 RVPYPRIPLKDVVPR-VEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEH 442 Query: 340 LDT 332 + T Sbjct: 443 IKT 445
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 71.6 bits (174), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1219 KVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1278 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1279 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRI 1337 Query: 346 EAL 338 A+ Sbjct: 1338 SAI 1340
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 71.6 bits (174), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1219 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1278 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1279 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRI 1337 Query: 346 EAL 338 A+ Sbjct: 1338 SAI 1340
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 71.6 bits (174), Expect = 2e-12 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 805 KICDFGLAR-DIRNDSNYVVKGNARLPVKWMAPESIFSCVYTFESDVWSYGIFLWELFSL 863 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P P+ ++M+ CWD +P KRP +VVQL+E Sbjct: 864 GSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIE 923
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 71.6 bits (174), Expect = 2e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + TGA + +MA E L + + K DV+SFG+ LWE+ Sbjct: 1220 KVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMT 1279 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYPD++ D++ ++ Q R P CP +M KCW + RP E+V + Sbjct: 1280 RGAPPYPDVNTFDITVYLL-QGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRI 1338 Query: 346 EAL 338 A+ Sbjct: 1339 SAI 1341
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 822 Score = 71.2 bits (173), Expect = 3e-12 Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI+DFG++R EA +G + + + APE L+ Y+ + DV+SFGI LWE + Sbjct: 698 KISDFGMSREEADGVYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLG 757 Query: 517 M-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+LS V + R P CP A +M +CW P +RP + Q +++ Sbjct: 758 ASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQS 816 Query: 340 L 338 + Sbjct: 817 I 817
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 71.2 bits (173), Expect = 3e-12 Identities = 40/113 (35%), Positives = 59/113 (52%), Gaps = 2/113 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 KI+DFG++R E +G + + APE L+ Y+ + DV+SFGI LWE + + Sbjct: 699 KISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGV 758 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 PYP ++ V + R P+ CP + IM KCWD P+ RP E+ Sbjct: 759 CPYPGMTNQQAREQV-ERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSEL 810
>KIT_FSVHZ (P04048) Tyrosine-protein kinase transforming protein kit (EC| 2.7.10.1) Length = 370 Score = 71.2 bits (173), Expect = 3e-12 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 245 KICDFGLAR-DIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSL 303 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 304 GSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 363
>KIT_CANFA (O97799) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 71.2 bits (173), Expect = 3e-12 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 806 KICDFGLAR-DIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSL 864 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 865 GSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 924
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 71.2 bits (173), Expect = 3e-12 Identities = 45/123 (36%), Positives = 68/123 (55%), Gaps = 3/123 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 K++DFG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY Sbjct: 329 KVSDFGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFG 383 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 +PYP + DV V + + D P CP A ++M+ CW + RP ++ + +E Sbjct: 384 RVPYPRIPLKDVVPR-VEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEH 442 Query: 340 LDT 332 + T Sbjct: 443 IRT 445
>KIT_FELCA (Q28889) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 71.2 bits (173), Expect = 3e-12 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 808 KICDFGLAR-DIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSL 866 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 867 GSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926
>KIT_CAPHI (Q28317) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 978 Score = 71.2 bits (173), Expect = 3e-12 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 809 KICDFGLAR-DIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSL 867 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 868 GSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 927
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 71.2 bits (173), Expect = 3e-12 Identities = 42/121 (34%), Positives = 65/121 (53%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI+DFG++R E TG + + APE L+ Y+ + DV+SFGI LWE + Sbjct: 409 KISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGRYSSESDVWSFGILLWEAFSLG 468 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 +PY +LS A+ Q +R + P CP +M++CW+ +P +RP V Q + A Sbjct: 469 AVPYANLSNQQTREAI-EQGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSFGAVHQDLIA 527 Query: 340 L 338 + Sbjct: 528 I 528
>KIT_BOVIN (P43481) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 977 Score = 71.2 bits (173), Expect = 3e-12 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 808 KICDFGLAR-DIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSL 866 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 867 GSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926
>KIT_HUMAN (P10721) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen) Length = 976 Score = 71.2 bits (173), Expect = 3e-12 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 4/120 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT---GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI DFG+AR + +N + A + +MAPE + Y + DV+S+GI LWE++ Sbjct: 807 KICDFGLAR-DIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSL 865 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ + R P P+ +IM+ CWD +P KRP ++VQL+E Sbjct: 866 GSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 925
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 71.2 bits (173), Expect = 3e-12 Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ +G + + APE + + + DV+SFGI +WE+ Sbjct: 754 KVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTY 813 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +LS +V A+ + R P CPSA +M +CW +RP ++V +++ Sbjct: 814 GERPYWELSNHEVMKAI-NDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILD 872 Query: 343 AL 338 L Sbjct: 873 KL 874
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 70.9 bits (172), Expect = 4e-12 Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 654 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 713 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +++ DV AV + R P CP+A +M CW + + RP DE+V +++ Sbjct: 714 GERPYWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLD 772 Query: 343 AL 338 L Sbjct: 773 KL 774
>EPHA7_CHICK (O42422) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEPHA7) (Tyrosine-protein kinase receptor CEK11) Length = 993 Score = 70.9 bits (172), Expect = 4e-12 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 4/137 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ Sbjct: 768 KVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 827 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A+ + R P CP+ +M CW +RP +++V +++ Sbjct: 828 GERPYWDMSNQDVIKAI-EEGYRLPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGILD 886 Query: 343 ALDTSKGGGMIPDGQSS 293 + + P G S Sbjct: 887 KMIRNPNSLKTPLGTCS 903
>EPHA7_MOUSE (Q61772) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1) Length = 998 Score = 70.9 bits (172), Expect = 4e-12 Identities = 39/137 (28%), Positives = 71/137 (51%), Gaps = 4/137 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ Sbjct: 773 KVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 832 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A+ + R P CP+ +M CW + +RP +++V +++ Sbjct: 833 GERPYWDMSNQDVIKAI-EEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILD 891 Query: 343 ALDTSKGGGMIPDGQSS 293 + + P G S Sbjct: 892 KMIRNPSSLKTPLGTCS 908
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 70.9 bits (172), Expect = 4e-12 Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 5/118 (4%) Frame = -2 Query: 691 KIADFGVARVEAQN----PKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 +IADFG+AR P+ A + +M+PE D + K DV+SFGICL+EI+ Sbjct: 336 RIADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFT 395 Query: 523 C-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 +PYPD+ + +H R P+ C ++M+ CW P+ RP+ V+ Sbjct: 396 LGQLPYPDVPSERIYE-YMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVE 452
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 70.9 bits (172), Expect = 4e-12 Identities = 44/125 (35%), Positives = 65/125 (52%), Gaps = 2/125 (1%) Frame = -2 Query: 691 KIADFGVARV-EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 K+ADFG+ARV + + + TGA + + APE + K DV+SFG+ L+EI Sbjct: 374 KVADFGLARVIDEEIYEAHTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGR 433 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYP ++ +V + QN R P CP F +IM CW +P RP + + +E Sbjct: 434 FPYPGMTNPEVLEKI-QQNYRMPCPANCPKQFHDIMLDCWREDPASRPTFETLQWQLEEF 492 Query: 337 DTSKG 323 S+G Sbjct: 493 FNSEG 497
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 70.9 bits (172), Expect = 4e-12 Identities = 37/122 (30%), Positives = 66/122 (54%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ +G + + APE + + + DV+S+GI +WE+ Sbjct: 755 KVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTY 814 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +LS +V A+ + R P CPSA +M +CW +RP ++V +++ Sbjct: 815 GERPYWELSNHEVMKAI-NDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILD 873 Query: 343 AL 338 L Sbjct: 874 KL 875
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 70.9 bits (172), Expect = 4e-12 Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 4/133 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTL---GYMAPEVLDGKP-YNRKCDVYSFGICLWEIYC 524 KI+DFG++ E MT G + + PE+ Y+ K DVY F + +WEI Sbjct: 247 KISDFGLS-AEKSREGSMTMTNGGICNPRWRPPELTKNLGHYSEKVDVYCFSLVVWEILT 305 Query: 523 CDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 ++P+ DL + S+ V + LRP IP C ++ +CW+ +P+ RP +V ++ Sbjct: 306 GEIPFSDLDGSQRSAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLK 365 Query: 343 ALDTSKGGGMIPD 305 + + G + D Sbjct: 366 EISWNNPIGFVSD 378
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 70.9 bits (172), Expect = 4e-12 Identities = 42/121 (34%), Positives = 65/121 (53%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI+DFG++R E TG + + APE L+ Y+ + DV+SFGI LWE + Sbjct: 749 KISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYGWYSSESDVWSFGILLWEAFSLG 808 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 +PY +LS A+ Q +R + P CP +M++CW+ +P +RP V Q + A Sbjct: 809 AVPYANLSNQQTREAI-EQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIA 867 Query: 340 L 338 + Sbjct: 868 I 868
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 70.9 bits (172), Expect = 4e-12 Identities = 38/122 (31%), Positives = 66/122 (54%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 791 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSY 850 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +++ DV AV + R P CP+A +M CW + + RP DE+V +++ Sbjct: 851 GERPYWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLD 909 Query: 343 AL 338 L Sbjct: 910 KL 911
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (CD333 antigen) Length = 806 Score = 70.9 bits (172), Expect = 4e-12 Identities = 50/155 (32%), Positives = 73/155 (47%), Gaps = 21/155 (13%) Frame = -2 Query: 691 KIADFGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KIADFG+AR + N K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 632 KIADFGLAR-DVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTL 690 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ ++ + R D P C IMR+CW P +RP ++V+ ++ Sbjct: 691 GGSPYPGIPVEELFK-LLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLD 749 Query: 343 ALDT-----------------SKGGGMIPDGQSSG 290 + T S GG P SSG Sbjct: 750 RVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSG 784
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1)| (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 70.5 bits (171), Expect = 5e-12 Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 22/156 (14%) Frame = -2 Query: 691 KIADFGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC- 524 KIADFG+AR + N K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 626 KIADFGLAR-DVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTP 684 Query: 523 -CDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYP + ++ ++ + R D P C IMR+CW P +RP ++V+ + Sbjct: 685 GGPSPYPGIPVEELFK-LLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDL 743 Query: 346 EALDT-----------------SKGGGMIPDGQSSG 290 + + T S GG P SSG Sbjct: 744 DRILTVTSTDEYLDLSVPFEQYSPGGQDTPSSSSSG 779
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 70.5 bits (171), Expect = 5e-12 Identities = 42/125 (33%), Positives = 68/125 (54%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R +P D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 768 KVSDFGLSRFLEDDPSDPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEV 826 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +AV Q+ R P CP+A +M CW + + RP ++V Sbjct: 827 MSYGERPYWDMSNQDVINAV-EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVN 885 Query: 352 LMEAL 338 ++ L Sbjct: 886 TLDKL 890
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 70.5 bits (171), Expect = 5e-12 Identities = 42/125 (33%), Positives = 68/125 (54%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R +P D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 773 KVSDFGLSRFLEDDPSDPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEV 831 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +AV Q+ R P CP+A +M CW + + RP ++V Sbjct: 832 MSYGERPYWDMSNQDVINAV-EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVN 890 Query: 352 LMEAL 338 ++ L Sbjct: 891 TLDKL 895
>EPHA7_RAT (P54759) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) Length = 998 Score = 70.5 bits (171), Expect = 5e-12 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 4/137 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ Sbjct: 773 KVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 832 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A + + R P CP+ +M CW +RP +++V +++ Sbjct: 833 GERPYWDMSNQDVIKA-IEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILD 891 Query: 343 ALDTSKGGGMIPDGQSS 293 + + P G S Sbjct: 892 KMIRNPSSLKTPLGTCS 908
>EPHA7_HUMAN (Q15375) Ephrin type-A receptor 7 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein-tyrosine kinase HEK11) Length = 998 Score = 70.5 bits (171), Expect = 5e-12 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 4/137 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ + TG + + APE + + + DV+S+GI +WE+ Sbjct: 773 KVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 832 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A + + R P CP+ +M CW +RP +++V +++ Sbjct: 833 GERPYWDMSNQDVIKA-IEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILD 891 Query: 343 ALDTSKGGGMIPDGQSS 293 + + P G S Sbjct: 892 KMIRNPNSLKTPLGTCS 908
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 70.5 bits (171), Expect = 5e-12 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-M 515 KIADFG+AR+ GA + + APE + + K DV+SFG+ L I + Sbjct: 368 KIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMVIVTYGRV 427 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 PYP +S +V ++ H P C P + +I+ +CW G P++RP + + ++E Sbjct: 428 PYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFY 487 Query: 334 TSKGG 320 T+ G Sbjct: 488 TATEG 492
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 70.5 bits (171), Expect = 5e-12 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR+ N GA + + APE ++ + K DV+SFGI L EI Sbjct: 372 KIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR 431 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP +S +V A+ H P P CP +IM +CW P++RP + + +++ Sbjct: 432 IPYPGMSNPEVIRALEHGYRMPR-PDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDF 490 Query: 337 DTS 329 T+ Sbjct: 491 YTA 493
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 70.5 bits (171), Expect = 5e-12 Identities = 52/152 (34%), Positives = 73/152 (48%), Gaps = 17/152 (11%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 638 KIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 697 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDE 362 PYP + ++ ++ + R D P C + +MR CW P +RP D+D Sbjct: 698 GSPYPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDR 756 Query: 361 VVQL---MEALDTS----KGGGMIPDGQSSGC 287 +V L E LD S + PD +SS C Sbjct: 757 IVALTSNQEYLDLSIPLDQYSPSFPDTRSSTC 788
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 70.5 bits (171), Expect = 5e-12 Identities = 52/152 (34%), Positives = 73/152 (48%), Gaps = 17/152 (11%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 638 KIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 697 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDE 362 PYP + ++ ++ + R D P C + +MR CW P +RP D+D Sbjct: 698 GSPYPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDR 756 Query: 361 VVQL---MEALDTS----KGGGMIPDGQSSGC 287 +V L E LD S + PD +SS C Sbjct: 757 IVALTSNQEYLDLSMPLDQYSPSFPDTRSSTC 788
>EPHA5_HUMAN (P54756) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 70.5 bits (171), Expect = 5e-12 Identities = 38/122 (31%), Positives = 65/122 (53%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 815 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +++ DV AV + R P CP+A +M CW + RP DE+V +++ Sbjct: 875 GERPYWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933 Query: 343 AL 338 L Sbjct: 934 KL 935
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 70.1 bits (170), Expect = 6e-12 Identities = 45/135 (33%), Positives = 65/135 (48%), Gaps = 7/135 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++P + A L +MAPE + K Y + DV+SFG+ +WEI+ Sbjct: 1018 KICDFGLARDVYKDPDYVRKGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFSLG 1077 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ---- 353 PYP L + + + R P S M CW G P +RP E+V+ Sbjct: 1078 ASPYPGLHIDEEFCCRLKEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGD 1137 Query: 352 LMEALDTSKGGGMIP 308 L++A +G IP Sbjct: 1138 LLQASVQQEGKHYIP 1152
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 70.1 bits (170), Expect = 6e-12 Identities = 42/123 (34%), Positives = 67/123 (54%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 KIADFG+AR ++ GA + + APE L ++ K DV++FG+ LWEI M Sbjct: 447 KIADFGLARFMKEDTYTAHAGAKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGM 506 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYP + ++V ++ R D P+ CP + +M +CW+ +P RP ++ +E L Sbjct: 507 APYPGVELSNV-YGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENL 565 Query: 337 DTS 329 +S Sbjct: 566 ISS 568
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 70.1 bits (170), Expect = 6e-12 Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 KI+DFG++R E +G + + APE L+ Y+ + DV+SFGI LWE + + Sbjct: 200 KISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGV 259 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYP ++ V + R P+ CP IM KCWD P+ RP ++ + + A+ Sbjct: 260 CPYPGMTNQQAREQV-ERGYRMSAPQNCPEEIFTIMMKCWDYKPENRPKFSDLHKELTAI 318
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC 2.7.10.2)| (C-FES) Length = 820 Score = 70.1 bits (170), Expect = 6e-12 Identities = 41/121 (33%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI+DFG++R EA +G + + APE L+ Y+ + DV+SFGI LWE + Sbjct: 696 KISDFGMSREEADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLG 755 Query: 517 M-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+LS V + R P CP A +M +CW P +RP + Q +++ Sbjct: 756 ASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQS 814 Query: 340 L 338 + Sbjct: 815 I 815
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 70.1 bits (170), Expect = 6e-12 Identities = 38/122 (31%), Positives = 67/122 (54%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P TG + + APE + + ++ DV+SFG+ +WE+ Sbjct: 775 KVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAY 834 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +++ DV S+V + R P CP A +M CW + +RP ++V +++ Sbjct: 835 GERPYWNMTNRDVISSV-EEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLD 893 Query: 343 AL 338 AL Sbjct: 894 AL 895
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 70.1 bits (170), Expect = 6e-12 Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR+ N GA + + APE ++ K DV+SFGI L EI Sbjct: 373 KIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTIKSDVWSFGILLMEIVTYGR 432 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP +S +V A+ + R P CP NIM +CW P++RP + + +++ Sbjct: 433 IPYPGMSNPEVIRAL-ERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDF 491 Query: 337 DTS 329 T+ Sbjct: 492 YTA 494
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 70.1 bits (170), Expect = 6e-12 Identities = 38/127 (29%), Positives = 67/127 (52%), Gaps = 4/127 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + +PE + + + DV+S+GI LWE+ Sbjct: 761 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSY 820 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +S DV AV + P P CP+A +M CW + + RP +++V +++ Sbjct: 821 GERPYSQMSNQDVIKAVDERYRLPP-PMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879 Query: 343 ALDTSKG 323 L + G Sbjct: 880 KLIRNPG 886
>EPHA3_CHICK (P29318) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (CEK4) Length = 983 Score = 70.1 bits (170), Expect = 6e-12 Identities = 37/122 (30%), Positives = 66/122 (54%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + +PE + + + D +S+GI LWE+ Sbjct: 761 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDAWSYGIVLWEVMSY 820 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY ++SF DV AV + R P CP+A +M CW + + RP +++V +++ Sbjct: 821 GERPYWEMSFQDVIKAV-DEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879 Query: 343 AL 338 L Sbjct: 880 KL 881
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 69.7 bits (169), Expect = 8e-12 Identities = 43/124 (34%), Positives = 66/124 (53%), Gaps = 4/124 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KIADFG+AR + N K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 626 KIADFGLAR-DVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTL 684 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ ++ + R D P C IMR+CW P +RP ++V+ ++ Sbjct: 685 GGSPYPGIPVEELFK-LLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLD 743 Query: 343 ALDT 332 + T Sbjct: 744 RVLT 747
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 69.7 bits (169), Expect = 8e-12 Identities = 42/120 (35%), Positives = 62/120 (51%), Gaps = 9/120 (7%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGT--------LGYMAPEVLDGKPYNRKCDVYSFGICLW 536 K+ADFG++R+ MTG T T + + APE L ++ K DV++FG+ LW Sbjct: 327 KVADFGLSRL-------MTGDTYTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLW 379 Query: 535 EIYCCDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 EI M PYP + + V ++ ++ R + P CP +MR CW NP RP E+ Sbjct: 380 EIATYGMSPYPGIDLSQVYE-LLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 69.7 bits (169), Expect = 8e-12 Identities = 42/114 (36%), Positives = 62/114 (54%), Gaps = 5/114 (4%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG----YMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+ARV + +D+ + + + APE + ++ K DV+SFGI L+EI Sbjct: 369 KVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIIT 428 Query: 523 CD-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMD 365 MPY ++ A V + QN R P CP F NIM +CW+ P +RP + Sbjct: 429 YGKMPYSGMTGAQVIQMLA-QNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFE 481
>EPHA5_RAT (P54757) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 69.7 bits (169), Expect = 8e-12 Identities = 37/122 (30%), Positives = 66/122 (54%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 817 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 876 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +++ DV AV + R P CP+A +M CW + + RP D++V +++ Sbjct: 877 GERPYWEMTNQDVIKAV-EEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLD 935 Query: 343 AL 338 L Sbjct: 936 KL 937
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 69.7 bits (169), Expect = 8e-12 Identities = 46/126 (36%), Positives = 66/126 (52%), Gaps = 2/126 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-D 518 KIADFG+ARV N GA + + APE ++ + K DV+SFGI L+EI Sbjct: 381 KIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK 440 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP + ADV SA + Q R CP +IM+ CW ++RP D + +++ Sbjct: 441 IPYPGRTNADVMSA-LSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDF 499 Query: 337 DTSKGG 320 T+ G Sbjct: 500 YTATEG 505
>EPHA3_RAT (O08680) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor REK4) (TYRO-4) Length = 984 Score = 69.3 bits (168), Expect = 1e-11 Identities = 38/127 (29%), Positives = 68/127 (53%), Gaps = 4/127 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + +PE + + DV+S+GI LWE+ Sbjct: 762 KVSDFGLSRVLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFTSASDVWSYGIVLWEVMSY 821 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY ++S DV AV + R +P CP+A +M CW + + RP +++V +++ Sbjct: 822 GERPYWEMSNQDVIKAV-DEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 880 Query: 343 ALDTSKG 323 L + G Sbjct: 881 KLIRNPG 887
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 69.3 bits (168), Expect = 1e-11 Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 K+ADFG AR + + G L +MA E L ++ K D++SFGI +WEI Sbjct: 625 KVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTLG 684 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP +S ADV V R + P C NIM CW +P +RP E++Q+++ Sbjct: 685 STPYPGISAADVMRKV-RDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDK 743 Query: 340 L 338 L Sbjct: 744 L 744
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 69.3 bits (168), Expect = 1e-11 Identities = 42/125 (33%), Positives = 68/125 (54%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R +P D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 763 KVSDFGLSRFLEDDPADPT-YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEV 821 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +AV Q+ R P CP+A +M CW + + RP ++V Sbjct: 822 MSYGERPYWDMSNQDVINAV-EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVN 880 Query: 352 LMEAL 338 ++ L Sbjct: 881 TLDKL 885
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC 2.7.10.1)| (FGFR-1) Length = 812 Score = 69.3 bits (168), Expect = 1e-11 Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 13/154 (8%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 632 KIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 691 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDE 362 PYP + ++ ++ + R D P C + +M+ CW P +RP D+D Sbjct: 692 GSPYPGVPMEELFK-LLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDR 750 Query: 361 VVQL---MEALDTSKGGGMIPDGQSSGCLCFTRA 269 ++ L E LD S +P Q S C TR+ Sbjct: 751 ILALSSNQEYLDLS-----MPVNQYSPCFPDTRS 779
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 68.9 bits (167), Expect = 1e-11 Identities = 43/119 (36%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR Q G L +M PE L + K D +SFG+ LWEI+ Sbjct: 657 KIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEGLFTSKTDSWSFGVLLWEIFSLG 716 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 MPYP + +V + N R D PR CP IM +CW P+ RPD +++ ++ Sbjct: 717 YMPYPGHTNQEVLDFIATGN-RMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSILERIQ 774
>EPHA3_HUMAN (P29320) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4) Length = 983 Score = 68.9 bits (167), Expect = 1e-11 Identities = 38/127 (29%), Positives = 68/127 (53%), Gaps = 4/127 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + +PE + + + DV+S+GI LWE+ Sbjct: 761 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSY 820 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY ++S DV AV + R P CP+A +M CW + + RP +++V +++ Sbjct: 821 GERPYWEMSNQDVIKAV-DEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILD 879 Query: 343 ALDTSKG 323 L + G Sbjct: 880 KLIRNPG 886
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 68.9 bits (167), Expect = 1e-11 Identities = 43/123 (34%), Positives = 67/123 (54%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR+ ++ + GA + + APE + ++ K DV+SFGI L E+ Sbjct: 385 KIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGR 444 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP ++ A+V + V H P P C P + IM +CW +P +RP + + +E Sbjct: 445 IPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLY-EIMLECWHKDPMRRPTFETLQWKLEDF 503 Query: 337 DTS 329 TS Sbjct: 504 YTS 506
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/121 (33%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI+DFG++R EA +G + + APE L+ Y+ + DV+SFGI LWE + Sbjct: 353 KISDFGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLG 412 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+LS + V + R P CP A +M +CW P +RP Q +++ Sbjct: 413 ASPYPNLS-NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQELQS 471 Query: 340 L 338 + Sbjct: 472 I 472
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 68.9 bits (167), Expect = 1e-11 Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 2/120 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ADFG++R+ + GA + + APE L ++ K DV++FG+ LWEI M Sbjct: 424 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGM 483 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PYP + + V ++ + R + P CP +MR CW +P RP E Q E + Sbjct: 484 SPYPGIDLSQVYD-LLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETM 542
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 68.9 bits (167), Expect = 1e-11 Identities = 45/126 (35%), Positives = 67/126 (53%), Gaps = 2/126 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+ARV N GA + + APE ++ + K DV+SFGI L+EI Sbjct: 381 KIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK 440 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP + ADV +A+ Q R CP +IM+ CW + ++RP D + +++ Sbjct: 441 IPYPGRTNADVMTAL-SQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDDF 499 Query: 337 DTSKGG 320 T+ G Sbjct: 500 YTATEG 505
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/126 (34%), Positives = 66/126 (52%), Gaps = 2/126 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-D 518 KIADFG+ARV N GA + + APE ++ + K DV+SFGI L+EI Sbjct: 381 KIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK 440 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP + ADV +A+ P + CP +IM+ CW ++RP D + +++ Sbjct: 441 IPYPGRTNADVMTALSQGYRMPRVEN-CPDELYDIMKMCWKEKAEERPTFDYLQSVLDDF 499 Query: 337 DTSKGG 320 T+ G Sbjct: 500 YTATEG 505
>EPHB3_BRARE (O13147) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK3) (EPH-like kinase 3) (Fragment) Length = 500 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/144 (30%), Positives = 71/144 (49%), Gaps = 7/144 (4%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R N D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 327 KVSDFGLSRFLDDNSSDPT-YTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEV 385 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +AV Q+ R P CP+ +M +CW + RP ++V Sbjct: 386 MSFGERPYWDMSNQDVMNAV-EQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVS 444 Query: 352 LMEALDTSKGGGMIPDGQSSGCLC 281 ++ + + SG LC Sbjct: 445 TLDKFLRNAASLKVLTSTHSGDLC 468
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 68.6 bits (166), Expect = 2e-11 Identities = 51/152 (33%), Positives = 73/152 (48%), Gaps = 17/152 (11%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 638 KIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 697 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP-------DMDE 362 P P + ++ ++ + R D P C + +MR CW+ P +RP D+D Sbjct: 698 GSPNPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDR 756 Query: 361 VVQL---MEALDTS----KGGGMIPDGQSSGC 287 +V L E LD S + PD +SS C Sbjct: 757 IVALTSNQEYLDLSMPLDQDSPSFPDTRSSTC 788
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 3/123 (2%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ +WEI+ Sbjct: 643 KIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG 702 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + ++ ++ + R D P C + +MR CW P +RP ++V+ ++ Sbjct: 703 GSPYPGIPVEELFK-LLKEGHRMDKPANCTNELYMMMRDCWQAVPSQRPTFKQLVEDLDR 761 Query: 340 LDT 332 + T Sbjct: 762 ILT 764
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 677 KVSDFGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEV 735 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP E+V Sbjct: 736 MSYGERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVN 794 Query: 352 LMEAL 338 ++ + Sbjct: 795 TLDKM 799
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 68.6 bits (166), Expect = 2e-11 Identities = 40/125 (32%), Positives = 68/125 (54%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 759 KVSDFGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEV 817 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP + E+V Sbjct: 818 MSFGERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVN 876 Query: 352 LMEAL 338 ++ + Sbjct: 877 TLDKM 881
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 759 KVSDFGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEV 817 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP E+V Sbjct: 818 MSFGERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVN 876 Query: 352 LMEAL 338 ++ + Sbjct: 877 TLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T +LG + APE + + + DV+S+GI +WE+ Sbjct: 759 KVSDFGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEV 817 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +A+ Q+ R P CP+A +M CW + + RP E+V Sbjct: 818 MSFGERPYWDMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVN 876 Query: 352 LMEAL 338 ++ + Sbjct: 877 TLDKM 881
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/124 (30%), Positives = 67/124 (54%), Gaps = 6/124 (4%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG-TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-D 518 K+ADFG+AR + +G T + + PEVL+ ++ K DV+++G+ +WEI+ C Sbjct: 662 KVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGK 721 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD----MDEVVQL 350 MPY L +V V + + + P+ C ++M+ CW P++RP MD++ + Sbjct: 722 MPYGRLKNTEVVER-VQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALV 780 Query: 349 MEAL 338 + L Sbjct: 781 AQTL 784
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 68.2 bits (165), Expect = 2e-11 Identities = 38/122 (31%), Positives = 65/122 (53%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++R +P+ G + + APE + + ++ DV+SFG+ +WE+ Sbjct: 142 KVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAY 201 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +++ DV S+V + R P CP A +M CW + +RP VV ++E Sbjct: 202 GERPYWNMTNQDVISSV-EEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLE 260 Query: 343 AL 338 AL Sbjct: 261 AL 262
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 3/123 (2%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ +WEI+ Sbjct: 641 KIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG 700 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + ++ ++ + R D P C + +MR CW P +RP ++V+ ++ Sbjct: 701 GSPYPGIPVEELFK-LLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDR 759 Query: 340 LDT 332 + T Sbjct: 760 ILT 762
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1)| (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 68.2 bits (165), Expect = 2e-11 Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 3/123 (2%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ +WEI+ Sbjct: 641 KIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG 700 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + ++ ++ + R D P C + +MR CW P +RP ++V+ ++ Sbjct: 701 GSPYPGIPVEELFK-LLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDR 759 Query: 340 LDT 332 + T Sbjct: 760 ILT 762
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/129 (34%), Positives = 62/129 (48%), Gaps = 4/129 (3%) Frame = -2 Query: 691 KIADFGVARV---EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K+ADFG+ARV + NP++ G + + APE + K DV+SFG+ + EI Sbjct: 201 KVADFGLARVIKEDIYNPRE--GTKFPIKWTAPEAALYNRFTIKSDVWSFGVLISEIVTH 258 Query: 520 D-MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 MPYP ++ V AV + R P CP IM CW PD RP + + L+E Sbjct: 259 GRMPYPGMTNRQVLEAV-DRGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPTFESLKNLLE 317 Query: 343 ALDTSKGGG 317 S G Sbjct: 318 DYYVSAAEG 326
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 67.8 bits (164), Expect = 3e-11 Identities = 46/135 (34%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KI DFG+AR +NP + G T L +MAPE + K Y+ K DV+S+G+ LWEI+ Sbjct: 1037 KICDFGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLG 1096 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ---- 353 PYP + + + + + +R P IM CW +P +RP E+V+ Sbjct: 1097 GSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGD 1156 Query: 352 LMEALDTSKGGGMIP 308 L++A G IP Sbjct: 1157 LLQANVQQDGKDYIP 1171
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 761 KVSDFGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEV 819 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D++ DV +A+ Q+ R P CPSA +M CW + + RP ++V Sbjct: 820 MSYGERPYWDMTNQDVINAI-EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVN 878 Query: 352 LMEAL 338 ++ + Sbjct: 879 TLDKM 883
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 67.8 bits (164), Expect = 3e-11 Identities = 46/135 (34%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KI DFG+AR +NP + G T L +MAPE + K Y+ K DV+S+G+ LWEI+ Sbjct: 1037 KICDFGLARDIYKNPDYVRRGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFSLG 1096 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ---- 353 PYP + + + + + +R P IM CW +P +RP E+V+ Sbjct: 1097 GSPYPGVQMDEDFCSRLKEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGD 1156 Query: 352 LMEALDTSKGGGMIP 308 L++A G IP Sbjct: 1157 LLQANVQQDGKDYIP 1171
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 67.8 bits (164), Expect = 3e-11 Identities = 40/121 (33%), Positives = 61/121 (50%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI+DFG++R A +G + + APE L+ Y+ + DV+SFGI LWE + Sbjct: 485 KISDFGMSREAADGIYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLG 544 Query: 517 M-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+LS V + R P CP A +M +CW P +RP + Q +++ Sbjct: 545 ASPYPNLSNQQTRE-FVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQS 603 Query: 340 L 338 + Sbjct: 604 I 604
>YS3J_CAEEL (Q19238) Putative tyrosine-protein kinase F09A5.2 in chromosome X (EC| 2.7.10.1) Length = 894 Score = 67.8 bits (164), Expect = 3e-11 Identities = 42/135 (31%), Positives = 69/135 (51%), Gaps = 4/135 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DM 515 K++DFG+ R G + +M+ E L ++ K DV+SFG+ L+EI+ D+ Sbjct: 668 KVSDFGLCRYMDSALYTAKGGRLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGDV 727 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV---VQLME 344 PYP + D+ ++ R P CP+ NIM+KCW P+ RP+ +E+ + +M Sbjct: 728 PYPTIQQVDMLEHLLAGG-RLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNEMRGEITVML 786 Query: 343 ALDTSKGGGMIPDGQ 299 LD G + + Q Sbjct: 787 NLDDESYGYLSVESQ 801
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 67.8 bits (164), Expect = 3e-11 Identities = 39/125 (31%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 769 KVSDFGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEV 827 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D++ DV +A+ Q+ R P CPSA +M CW + + RP ++V Sbjct: 828 MSYGERPYWDMTNQDVINAI-EQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVN 886 Query: 352 LMEAL 338 ++ + Sbjct: 887 TLDKM 891
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/119 (36%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +MAPE L + D++SFG+ LWEI Sbjct: 1174 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLA 1233 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY LS V V+ D P CP ++MR CW NP RP E+V L++ Sbjct: 1234 EQPYQGLSNEQVLKFVMDGGYL-DQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK 1291
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 67.8 bits (164), Expect = 3e-11 Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARV--EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR K T + +MAPE L + Y + DV+SFG+ LWEI+ Sbjct: 636 KIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 695 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + ++ ++ + R D P C + +MR CW P +RP ++V+ ++ Sbjct: 696 GSPYPGVPVEELFK-LLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDR 754 Query: 340 L 338 + Sbjct: 755 I 755
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 67.4 bits (163), Expect = 4e-11 Identities = 41/125 (32%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 749 KVSDFGLSRFLENSRSDPT-YTSALGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEV 807 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +A+ Q+ R P CPSA +M CW + + RP ++V Sbjct: 808 MSYGERPYWDMSNQDVINAI-EQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQIVS 866 Query: 352 LMEAL 338 ++ L Sbjct: 867 SLDKL 871
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 67.4 bits (163), Expect = 4e-11 Identities = 46/135 (34%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KI DFG+AR +NP + G T L +MAPE + K Y+ K DV+S+G+ LWEI+ Sbjct: 1037 KICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLG 1096 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ---- 353 PYP + + + + + +R P IM CW +P +RP E+V+ Sbjct: 1097 GSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGD 1156 Query: 352 LMEALDTSKGGGMIP 308 L++A G IP Sbjct: 1157 LLQANVQQDGKDYIP 1171
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/125 (32%), Positives = 69/125 (55%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARV---EAQNPKDMTGATGT---LGYMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R +A NP TGA G + + APE + + + DV+S+GI +WE+ Sbjct: 777 KVSDFGLSRFLEDDASNPT-YTGALGCKIPIRWTAPEAVQYRKFTSSSDVWSYGIVMWEV 835 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +A + Q+ R P CP+ +M CW + +RP +++V Sbjct: 836 MSYGERPYWDMSNQDVINA-IDQDYRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIVS 894 Query: 352 LMEAL 338 ++ + Sbjct: 895 ALDKM 899
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/121 (33%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KIADFG+AR + + + T + +MAPE L K Y+ + DV+S+G+ LWEI Sbjct: 879 KIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYG 938 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 D PYP + A+ + + R + P C +MR+CW RP E+V+ + Sbjct: 939 DQPYPHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELVESFDG 998 Query: 340 L 338 + Sbjct: 999 I 999
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 67.4 bits (163), Expect = 4e-11 Identities = 37/124 (29%), Positives = 66/124 (53%), Gaps = 6/124 (4%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-----GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIY 527 K++DFG++R +N D T G ++ + APE + + + D +S+GI +WE+ Sbjct: 755 KVSDFGLSRFLEENSSDPTYTSSLGGKISIRWTAPEAIAFRKFTSASDAWSYGIVMWEVM 814 Query: 526 CC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQL 350 + PY D+S DV +A+ Q+ R P CP++ +M CW + + RP +VV Sbjct: 815 SFGERPYWDMSNQDVINAI-EQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSA 873 Query: 349 MEAL 338 ++ + Sbjct: 874 LDKM 877
>EPA4B_XENLA (Q91694) Ephrin type-A receptor 4-B precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor PAG) (Pagliaccio) Length = 985 Score = 67.0 bits (162), Expect = 5e-11 Identities = 37/122 (30%), Positives = 63/122 (51%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 760 KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 819 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A+ + R P CP A +M CW + RP ++V +++ Sbjct: 820 GERPYWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSMLD 878 Query: 343 AL 338 L Sbjct: 879 KL 880
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 67.0 bits (162), Expect = 5e-11 Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + D++SFG+ LWEI Sbjct: 1175 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLA 1234 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY LS V V+ D P CP ++MR CW NP RP E+V L++ Sbjct: 1235 EQPYQGLSNEQVLKFVMDGGYL-DPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1292
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 67.0 bits (162), Expect = 5e-11 Identities = 44/114 (38%), Positives = 57/114 (50%), Gaps = 3/114 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR +N G L +MAPE L + + DV+SFGI +WEI Sbjct: 2099 KIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLG 2158 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 PYP S DV + V R + PR CP N+M +CW PD+RP + Sbjct: 2159 HQPYPAHSNLDVLN-YVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 67.0 bits (162), Expect = 5e-11 Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + D++SFG+ LWEI Sbjct: 1164 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITSLA 1223 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY LS V V+ D P CP ++MR CW NP RP E+V L++ Sbjct: 1224 EQPYQGLSNEQVLKFVMDGGYL-DPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1281
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 67.0 bits (162), Expect = 5e-11 Identities = 39/125 (31%), Positives = 67/125 (53%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R +N D T T +LG + APE + + + D +S+GI +WE+ Sbjct: 755 KVSDFGLSRFLEENSSDPT-YTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEV 813 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D+S DV +A+ Q+ R P CP++ +M CW + + RP +VV Sbjct: 814 MSFGERPYWDMSNQDVINAI-EQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVS 872 Query: 352 LMEAL 338 ++ + Sbjct: 873 ALDKM 877
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/130 (32%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ Sbjct: 591 KIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM 650 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 +PY +++ D +V + L PD+ + CP A +M +C D+RP ++ Sbjct: 651 TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQI 710 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 711 LASIELLARS 720
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/130 (32%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ Sbjct: 217 KIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM 276 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 +PY +++ D +V + L PD+ + CP A +M +C D+RP ++ Sbjct: 277 TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQI 336 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 337 LASIELLARS 346
>PGFRB_RAT (Q05030) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1097 Score = 66.6 bits (161), Expect = 7e-11 Identities = 43/121 (35%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++ ++ G+T L +MAPE + Y DV+SFGI LWEI+ Sbjct: 840 KICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLG 899 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+L D + + R P IM+KCW+ + RP ++V L+E Sbjct: 900 GTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLER 959 Query: 340 L 338 L Sbjct: 960 L 960
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/130 (32%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ Sbjct: 201 KIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM 260 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 +PY +++ D +V + L PD+ + CP A +M +C D+RP ++ Sbjct: 261 TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQI 320 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 321 LASIELLARS 330
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/130 (32%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ Sbjct: 153 KIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM 212 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 +PY +++ D +V + L PD+ + CP A +M +C D+RP ++ Sbjct: 213 TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQI 272 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 273 LASIELLARS 282
>PGFRB_MOUSE (P05622) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1098 Score = 66.6 bits (161), Expect = 7e-11 Identities = 43/121 (35%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++ ++ G+T L +MAPE + Y DV+SFGI LWEI+ Sbjct: 840 KICDFGLARDIMRDSNYISKGSTYLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLG 899 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+L D + + R P IM+KCW+ + RP ++V L+E Sbjct: 900 GTPYPELPMNDQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPFSQLVLLLER 959 Query: 340 L 338 L Sbjct: 960 L 960
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 66.6 bits (161), Expect = 7e-11 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 766 KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVISY 825 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY ++S DV AV + R P CP +M CW+ N RP ++V ++ Sbjct: 826 GERPYWEMSNQDVIKAV-DEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLD 884 Query: 343 AL 338 L Sbjct: 885 RL 886
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 66.6 bits (161), Expect = 7e-11 Identities = 38/131 (29%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Frame = -2 Query: 691 KIADFGVARVEAQNP------KDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFG 548 K++DFG++RV ++P +++TG + G + APE + + + DV+S+G Sbjct: 135 KVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYRKFTSASDVWSYG 194 Query: 547 ICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPD 371 I +WE+ + PY D+S DV A+ + R P CP + +M CW +RP Sbjct: 195 IVMWEVMSYGERPYWDMSNQDVIKAI-EEGYRLPPPMDCPVSLHQLMLDCWQKERAERPK 253 Query: 370 MDEVVQLMEAL 338 ++V +++ L Sbjct: 254 FSQIVNMLDKL 264
>EPHA4_MOUSE (Q03137) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (MPK-3) Length = 986 Score = 66.6 bits (161), Expect = 7e-11 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 761 KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 820 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A+ + R P CP A +M CW RP ++V +++ Sbjct: 821 GERPYWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879 Query: 343 AL 338 L Sbjct: 880 KL 881
>EPHA4_HUMAN (P54764) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8) Length = 986 Score = 66.6 bits (161), Expect = 7e-11 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 761 KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 820 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A+ + R P CP A +M CW RP ++V +++ Sbjct: 821 GERPYWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879 Query: 343 AL 338 L Sbjct: 880 KL 881
>EPHA4_CHICK (Q07496) Ephrin type-A receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK8) Length = 986 Score = 66.6 bits (161), Expect = 7e-11 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 761 KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 820 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A+ + R P CP A +M CW RP ++V +++ Sbjct: 821 GERPYWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879 Query: 343 AL 338 L Sbjct: 880 KL 881
>EPA4A_XENLA (Q91845) Ephrin type-A receptor 4-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor SEK-1) (xSEK-1) Length = 986 Score = 66.6 bits (161), Expect = 7e-11 Identities = 37/122 (30%), Positives = 62/122 (50%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ G + + APE + + + DV+S+GI +WE+ Sbjct: 760 KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 819 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY D+S DV A+ + R P CP A +M CW RP ++V +++ Sbjct: 820 GERPYWDMSNQDVIKAI-EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSMLD 878 Query: 343 AL 338 L Sbjct: 879 KL 880
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/130 (32%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ Sbjct: 631 KIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM 690 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 +PY +++ D +V + L PD+ + CP A +M +C D+RP ++ Sbjct: 691 TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQI 750 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 751 LASIELLARS 760
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 66.6 bits (161), Expect = 7e-11 Identities = 38/125 (30%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 762 KVSDFGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEV 820 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D++ DV +A+ Q+ R P CP+A +M CW + + RP ++V Sbjct: 821 MSYGERPYWDMTNQDVINAI-EQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVN 879 Query: 352 LMEAL 338 ++ + Sbjct: 880 TLDKM 884
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 66.6 bits (161), Expect = 7e-11 Identities = 38/125 (30%), Positives = 66/125 (52%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T LG + APE + + + DV+S+GI +WE+ Sbjct: 779 KVSDFGLSRFLEDDTSDPT-YTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEV 837 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY D++ DV +A+ Q+ R P CP+A +M CW + + RP ++V Sbjct: 838 MSYGERPYWDMTNQDVINAI-EQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVN 896 Query: 352 LMEAL 338 ++ + Sbjct: 897 TLDKM 901
>SPK1_DUGTI (P42687) Tyrosine-protein kinase SPK-1 (EC 2.7.10.2)| Length = 497 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/126 (33%), Positives = 59/126 (46%), Gaps = 8/126 (6%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYM--APEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 K+ADFG+ + + D T Y APE K + K DV+S+GI ++EI Sbjct: 357 KVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILTWA 416 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPR-----CCPSAFANIMRKCWDGNPDKRPDMDEVV 356 PYPD+ +V V P+ + CCP IM CWD NP+KRP + Sbjct: 417 SSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQ 476 Query: 355 QLMEAL 338 + M+ L Sbjct: 477 EKMDLL 482
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 66.6 bits (161), Expect = 7e-11 Identities = 42/130 (32%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ +G++ +MAPEV+ D PY+ + DVY+FGI L+E+ Sbjct: 631 KIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM 690 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 +PY +++ D +V + L PD+ + CP A +M +C D+RP ++ Sbjct: 691 TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQI 750 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 751 LASIELLARS 760
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 66.2 bits (160), Expect = 9e-11 Identities = 37/122 (30%), Positives = 65/122 (53%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++R +P+ G + + APE + + ++ DV+SFG+ +WE+ Sbjct: 774 KVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAY 833 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY +++ DV S+V + R P CP A +M CW + +RP VV +++ Sbjct: 834 GERPYWNMTNQDVISSV-EEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLD 892 Query: 343 AL 338 AL Sbjct: 893 AL 894
>CSK_MOUSE (P41241) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase MPK-2) (p50CSK) Length = 450 Score = 66.2 bits (160), Expect = 9e-11 Identities = 44/123 (35%), Positives = 67/123 (54%), Gaps = 3/123 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 K++DFG+ + EA + +D TG L + APE L K ++ K DV+SFGI LWEIY Sbjct: 329 KVSDFGLTK-EASSTQD----TGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFG 383 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 +PYP + DV V + + D P CP A ++M+ C + RP ++ + +E Sbjct: 384 RVPYPRIPLKDVVPR-VEKGYKMDAPDGCPPAVYDVMKNCSHLDAATRPTFLQLREQLEH 442 Query: 340 LDT 332 + T Sbjct: 443 IKT 445
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 66.2 bits (160), Expect = 9e-11 Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDM-TGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ADFG+AR+ + GA + + APE L ++ K DV++FG+ LWEI M Sbjct: 507 KVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGM 566 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + DV + + R + P CP ++MR+CW + RP + +E Sbjct: 567 SPYPAIDLTDVYHK-LDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALE 623
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 66.2 bits (160), Expect = 9e-11 Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 4/124 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KIADFG+AR + N K + + +MAPE L + Y + DV+SFG+ +WEI+ Sbjct: 631 KIADFGLAR-DVNNIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL 689 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP + ++ ++ + R D P C + +MR CW P RP ++V+ ++ Sbjct: 690 GGSPYPGIPVEELFK-LLKEGHRMDKPANCTNELYMMMRDCWHAIPSHRPTFKQLVEDLD 748 Query: 343 ALDT 332 + T Sbjct: 749 RILT 752
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 65.9 bits (159), Expect = 1e-10 Identities = 42/115 (36%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + DV+SFG+ LWEI Sbjct: 1152 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLA 1211 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + PY LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 1212 EQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1265
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 65.9 bits (159), Expect = 1e-10 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -2 Query: 613 YMAPEVLDGKPYN---RKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIP 443 ++APE L KP + R D++SF + LWE+ ++P+ DLS ++ V + LRP IP Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIP 414 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +M+ C + +P KRP D +V ++E + Sbjct: 415 PGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKM 449
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 65.9 bits (159), Expect = 1e-10 Identities = 42/115 (36%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + DV+SFG+ LWEI Sbjct: 1151 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLA 1210 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + PY LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 1211 EQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1264
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 65.9 bits (159), Expect = 1e-10 Identities = 45/132 (34%), Positives = 67/132 (50%), Gaps = 4/132 (3%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE ++ + K DV+SFGI L EI Sbjct: 378 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR 437 Query: 517 MPYPDLSFADVSSAVV--HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ +V + ++ +RPD CP +MR CW P+ RP D + ++E Sbjct: 438 IPYPGMTNPEVIQNLERGYRMVRPDN---CPEELYQLMRLCWKERPEDRPTFDYLRSVLE 494 Query: 343 ALDTSKGGGMIP 308 T+ G P Sbjct: 495 DFFTATEGQYQP 506
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 65.9 bits (159), Expect = 1e-10 Identities = 42/115 (36%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + DV+SFG+ LWEI Sbjct: 423 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLA 482 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + PY LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 483 EQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 536
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/95 (32%), Positives = 53/95 (55%), Gaps = 3/95 (3%) Frame = -2 Query: 613 YMAPEVLDGKPYN---RKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIP 443 ++APE L KP + R D++SF + LWE+ ++P+ DLS ++ V + LRP +P Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTVP 414 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +M+ C + +P KRP D +V ++E + Sbjct: 415 PGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKM 449
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CDM 515 KI+DFG++R E + + + APE L+ Y CDV+S+GI +WEI+ D Sbjct: 1200 KISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDT 1259 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 PY ++ + + R P+ P +M +CW + + RP DE+ +++AL Sbjct: 1260 PYSGMTNSRARER-IDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDAL 1317
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/115 (36%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + DV+SFG+ LWEI Sbjct: 1150 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLA 1209 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + PY LS V V+ L D P CP +MR CW NP RP E++ Sbjct: 1210 EQPYQGLSNEQVLRFVMEGGLL-DKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1263
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 65.5 bits (158), Expect = 1e-10 Identities = 43/130 (33%), Positives = 64/130 (49%), Gaps = 2/130 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE ++ + K DV+SFGI + EI Sbjct: 378 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILMTEIVTHGR 437 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP ++ +V + + R P CP +M +CW PD RP D + ++E Sbjct: 438 IPYPGMTNPEVIQNL-ERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDF 496 Query: 337 DTSKGGGMIP 308 T+ G P Sbjct: 497 FTATEGQYQP 506
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 65.5 bits (158), Expect = 1e-10 Identities = 35/122 (28%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ TG + + APE + + ++ DV+S+GI +WE+ Sbjct: 812 KVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSYGIVMWEVMSY 871 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY ++S DV + + + R P CP + +M CW + RP ++V ++ Sbjct: 872 GERPYWEMSNQDVILS-IEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLD 930 Query: 343 AL 338 L Sbjct: 931 KL 932
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/124 (35%), Positives = 63/124 (50%), Gaps = 2/124 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DM 515 KIADFG++R E K G + +MA E L+ Y K DV+SFG+ LWEI Sbjct: 40 KIADFGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGT 98 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEAL 338 PY ++ A++ + Q R + PR C +MR+CW P +RP ++ VQL Sbjct: 99 PYCGMTCAELYEK-LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQ 157 Query: 337 DTSK 326 + K Sbjct: 158 EARK 161
>ALK_HUMAN (Q9UM73) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1620 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR + G L +M PE + K D +SFG+ LWEI+ Sbjct: 1267 KIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLG 1326 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 MPYP S +V V R D P+ CP IM +CW P+ RP+ +++ +E Sbjct: 1327 YMPYPSKSNQEVLEFVTSGG-RMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIE 1384
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 411 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 470 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP + +V V + R P+ CP + +MR+CW PD+RP + + +E Sbjct: 471 VPYPGMVNREVLEQV-DRGYRMPCPQGCPESLHEMMRQCWKKEPDERPTFEYIQSFLE 527
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 2/124 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DM 515 KIADFG++R E K G + +MA E L+ Y K DV+SFG+ LWEI Sbjct: 990 KIADFGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGT 1048 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEAL 338 PY ++ A++ + Q R + PR C +MR+CW P +RP ++ +QL L Sbjct: 1049 PYCGMTCAELYEK-LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRML 1107 Query: 337 DTSK 326 + K Sbjct: 1108 EARK 1111
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 65.1 bits (157), Expect = 2e-10 Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD-M 515 KIADFG+AR+ GA + + APE + + K DV+SFG+ L E+ + Sbjct: 374 KIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRV 433 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEALD 335 PYP +S +V + P C P + ++ +CW P++RP + + ++E Sbjct: 434 PYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFY 493 Query: 334 TS 329 T+ Sbjct: 494 TA 495
>ALK_MOUSE (P97793) ALK tyrosine kinase receptor precursor (EC 2.7.10.1)| (Anaplastic lymphoma kinase) (CD246 antigen) Length = 1621 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR + G L +M PE + K D +SFG+ LWEI+ Sbjct: 1271 KIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLG 1330 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 MPYP S +V V R D P+ CP IM +CW P+ RP+ +++ +E Sbjct: 1331 YMPYPSKSNQEVLEFVTSGG-RMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIE 1388
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 2/124 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DM 515 KIADFG++R E K G + +MA E L+ Y K DV+SFG+ LWEI Sbjct: 994 KIADFGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGT 1052 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEAL 338 PY ++ A++ + Q R + PR C +MR+CW P +RP ++ +QL L Sbjct: 1053 PYCGMTCAELYEK-LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRML 1111 Query: 337 DTSK 326 + K Sbjct: 1112 EARK 1115
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 64.7 bits (156), Expect = 3e-10 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 2/126 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE ++ + K DV+SFGI L EI Sbjct: 377 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGR 436 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP ++ +V + + R P CP +M +CW P++RP + + ++E Sbjct: 437 IPYPGMTNPEVIQNL-ERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDF 495 Query: 337 DTSKGG 320 T+ G Sbjct: 496 FTATEG 501
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 64.7 bits (156), Expect = 3e-10 Identities = 43/126 (34%), Positives = 59/126 (46%), Gaps = 20/126 (15%) Frame = -2 Query: 691 KIADFGVARVEA---------QNPKDMTGAT-----GTLGYMAPEVLD---GKPYNRKCD 563 KIAD GVA + K+++ T GTL YMAPE L+ KP K D Sbjct: 153 KIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKP-TEKSD 211 Query: 562 VYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIPRC---CPSAFANIMRKCWDG 392 VYSFGI LW I+ PY ++ + + RP++ CP ++M +CW Sbjct: 212 VYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQA 271 Query: 391 NPDKRP 374 P+ RP Sbjct: 272 IPEDRP 277
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 820 Score = 64.7 bits (156), Expect = 3e-10 Identities = 39/121 (32%), Positives = 60/121 (49%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI+DFG++R EA + + APE L+ Y+ + DV+SFGI LWE + Sbjct: 696 KISDFGMSREEADGIYAACSGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLG 755 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+L+ + V + R P CP A +M +CW P +RP + Q + + Sbjct: 756 ASPYPNLT-NQQTREFVEKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSIICQELHS 814 Query: 340 L 338 + Sbjct: 815 I 815
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 64.7 bits (156), Expect = 3e-10 Identities = 34/122 (27%), Positives = 64/122 (52%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ TG + + APE + + ++ D +S+GI +WE+ Sbjct: 812 KVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSY 871 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY ++S DV ++ + R P CP++ +M CW + RP ++V ++ Sbjct: 872 GERPYWEMSNQDVILSI-EEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLD 930 Query: 343 AL 338 L Sbjct: 931 KL 932
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 64.7 bits (156), Expect = 3e-10 Identities = 49/162 (30%), Positives = 72/162 (44%), Gaps = 9/162 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKD--------MTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLW 536 KI+ FG + P+D M+G + L + APE L ++ DV+SFGI +W Sbjct: 785 KISGFG------RGPRDRSEAVYTTMSGRSPAL-WAAPETLQFGHFSSASDVWSFGIIMW 837 Query: 535 EIYCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 E+ + PY D+S DV AV R PR CP+ +M CW +P +RP ++ Sbjct: 838 EVMAFGERPYWDMSGQDVIKAV-EDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQI 896 Query: 358 VQLMEALDTSKGGGMIPDGQSSGCLCFTRARGP*TLCTALFS 233 ++ M+ D + C T R P L FS Sbjct: 897 HSILSK--------MVQDPEPPKCALTTCPRPPTPLADRAFS 930
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 64.3 bits (155), Expect = 3e-10 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 404 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVAKGR 463 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP + +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 464 VPYPGMVNREVLEQV-ERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFLE 520
>PGFRB_HUMAN (P09619) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) (CD140b antigen) Length = 1106 Score = 64.3 bits (155), Expect = 3e-10 Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KI DFG+AR ++ ++ G+T L +MAPE + Y DV+SFGI LWEI+ Sbjct: 841 KICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLG 900 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+L + + + R P IM+KCW+ + RP ++V L+E Sbjct: 901 GTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLER 960 Query: 340 L 338 L Sbjct: 961 L 961
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 64.3 bits (155), Expect = 3e-10 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPK-DMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC-CD 518 KI+DFG+AR + +GA + + PEV Y+ K DV+SFG+ +WE++ Sbjct: 405 KISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGK 464 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 MP+ + S V A + Q R P P +M CW +P RP E++Q++ Sbjct: 465 MPFENKSNLQVVEA-ISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVL 520
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 64.3 bits (155), Expect = 3e-10 Identities = 41/119 (34%), Positives = 58/119 (48%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR A + A + +M PE + K D +SFG+ LWEI+ Sbjct: 661 KIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLG 720 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 MPYP + +V VV R D PR CP IM +CW P+ RP +++ ++ Sbjct: 721 YMPYPGRTNQEVLDFVVGGG-RMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQ 778
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/122 (27%), Positives = 63/122 (51%), Gaps = 4/122 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATG---TLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K++DFG++RV +P+ TG + + APE + + ++ D +S+GI +WE+ Sbjct: 812 KVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSY 871 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY ++S DV ++ + R P CP + +M CW + RP ++V ++ Sbjct: 872 GERPYWEMSNQDVILSI-EEGYRLPAPMGCPPSLQQLMLHCWQKERNHRPKFTDIVSFLD 930 Query: 343 AL 338 L Sbjct: 931 KL 932
>PGFRB_CANFA (Q6QNF3) Beta platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-beta) Length = 1103 Score = 64.3 bits (155), Expect = 3e-10 Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT-GATGT-LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KI DFG+AR ++ ++ G+T L +MAPE + Y DV+SFGI LWEI+ Sbjct: 841 KICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLG 900 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP+L + + + R P IM+KCW+ + RP ++V L+E Sbjct: 901 GTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLER 960 Query: 340 L 338 L Sbjct: 961 L 961
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/124 (35%), Positives = 64/124 (51%), Gaps = 2/124 (1%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DM 515 KIADFG++R E K G + +MA E L+ Y K DV+SFG+ LWEI Sbjct: 992 KIADFGLSRGEEVYVKKTMGRL-PVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGT 1050 Query: 514 PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEAL 338 PY ++ A++ + Q R + PR C +MR+CW P +RP ++ +QL L Sbjct: 1051 PYCGMTCAELYEK-LPQAYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRML 1109 Query: 337 DTSK 326 + K Sbjct: 1110 EARK 1113
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 401 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 460 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP + +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 461 VPYPGMVNREVLEQV-ERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLE 517
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 408 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 467 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP + +V V + R P+ CP + +M+ CW +PD+RP + + +E Sbjct: 468 VPYPGMVNREVLEQV-ERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLE 524
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/115 (34%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + DV+SFG+ LWEI Sbjct: 1146 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLA 1205 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 + PY +S V V+ L + P CP +MR CW NP RP E++ Sbjct: 1206 EQPYQGMSNEQVLRFVMEGGLL-EKPDNCPDMLFELMRMCWQFNPKMRPSFLEII 1259
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 63.9 bits (154), Expect = 4e-10 Identities = 44/132 (33%), Positives = 67/132 (50%), Gaps = 4/132 (3%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE ++ + K DV+SFGI L EI Sbjct: 378 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR 437 Query: 517 MPYPDLSFADVSSAVV--HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ +V + ++ +RPD CP ++M CW P+ RP D + ++E Sbjct: 438 IPYPGMTNPEVIQNLERGYRMVRPDN---CPEELYHLMMLCWKERPEDRPTFDYLRSVLE 494 Query: 343 ALDTSKGGGMIP 308 T+ G P Sbjct: 495 DFFTATEGQYQP 506
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 63.9 bits (154), Expect = 4e-10 Identities = 38/115 (33%), Positives = 64/115 (55%), Gaps = 4/115 (3%) Frame = -2 Query: 691 KIADFGVARVEAQNP---KDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KI+DFG++R + G + + APE ++ ++ K DV+S+GI LWE++ Sbjct: 623 KISDFGLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYGTFSTKSDVWSYGITLWEMFTF 682 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 D+PY +++ +V S + H R + P CP +IM CW +P+KRP +E+ Sbjct: 683 GDLPYGEMTGNEVVSFLEHCG-RLEKPDECPIHTYSIMLSCWHIDPNKRPTFNEL 736
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 63.5 bits (153), Expect = 6e-10 Identities = 38/116 (32%), Positives = 57/116 (49%), Gaps = 3/116 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++P + A L +MAPE + + Y + DV+SFG+ LWEI+ Sbjct: 1036 KICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLG 1095 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 PYP + + + + R P M CW G+P +RP E+V+ Sbjct: 1096 ASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTFSELVE 1151
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 63.5 bits (153), Expect = 6e-10 Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 3/116 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++P + A L +MAPE + + Y + DV+SFG+ LWEI+ Sbjct: 1043 KICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLG 1102 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 PYP + + + + R P M CW G P +RP E+V+ Sbjct: 1103 ASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVE 1158
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 63.5 bits (153), Expect = 6e-10 Identities = 40/119 (33%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +M+PE L + DV+SFG+ LWEI Sbjct: 1163 KIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLA 1222 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY LS V V+ D P CP ++M+ CW NP RP E++ +++ Sbjct: 1223 EQPYQGLSNEQVLKFVMDGGSL-DHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLK 1280
>RAF_MSV36 (P00532) Serine/threonine-protein kinase transforming protein raf| (EC 2.7.11.1) Length = 323 Score = 63.2 bits (152), Expect = 7e-10 Identities = 40/130 (30%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ Sbjct: 158 KIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELM 217 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 ++PY ++ D +V + PD+ R CP A ++ C ++RP ++ Sbjct: 218 AGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAIKRLVADCVKKVKEERPLFPQI 277 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 278 LSSIELLQHS 287
>RAF1_RAT (P11345) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 63.2 bits (152), Expect = 7e-10 Identities = 40/130 (30%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ Sbjct: 483 KIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELM 542 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 ++PY ++ D +V + PD+ R CP A ++ C ++RP ++ Sbjct: 543 TGELPYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQI 602 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 603 LSSIELLQHS 612
>RAF1_MOUSE (Q99N57) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 63.2 bits (152), Expect = 7e-10 Identities = 40/130 (30%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ Sbjct: 483 KIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELM 542 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 ++PY ++ D +V + PD+ R CP A ++ C ++RP ++ Sbjct: 543 AGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKEERPLFPQI 602 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 603 LSSIELLQHS 612
>KRAF1_CAEEL (Q07292) Raf homolog serine/threonine-protein kinase (EC 2.7.11.1)| (Abnormal cell lineage protein 45) Length = 813 Score = 63.2 bits (152), Expect = 7e-10 Identities = 42/124 (33%), Positives = 66/124 (53%), Gaps = 11/124 (8%) Frame = -2 Query: 691 KIADFGVARVEAQ----NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWE 533 KI DFG+A V+ + + TG++ +MAPEV+ D PY + DVYSFGIC++E Sbjct: 618 KIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYE 677 Query: 532 IYCCDMPYPDLSFADVSSAVVHQN-LRPD---IPRCCPSAFANIMRKCWDGNPDKRPDMD 365 I +PY +++ D +V + LRPD I P + + C + ++RP Sbjct: 678 ILSSHLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFG 737 Query: 364 EVVQ 353 EV++ Sbjct: 738 EVLE 741
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 63.2 bits (152), Expect = 7e-10 Identities = 43/125 (34%), Positives = 57/125 (45%), Gaps = 19/125 (15%) Frame = -2 Query: 691 KIADFGVARV---------EAQNPKDMTGAT----GTLGYMAPEVLD---GKPYNRKCDV 560 KIAD G+A E +++ G GTL YMAPE L+ KP K DV Sbjct: 153 KIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKP-TEKSDV 211 Query: 559 YSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPD---IPRCCPSAFANIMRKCWDGN 389 YSF + LW I+ PY + + RPD I CP ++M+ CW+ N Sbjct: 212 YSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEAN 271 Query: 388 PDKRP 374 P+ RP Sbjct: 272 PEARP 276
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 63.2 bits (152), Expect = 7e-10 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 7/118 (5%) Frame = -2 Query: 691 KIADFGVARV-----EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIY 527 KI+DFG++R + + + APE ++ + DV++FG+CLWE++ Sbjct: 275 KISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMF 334 Query: 526 CCDM-PYPDLSFADVSSAVVHQNL-RPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV 359 P+ L+ + A+ N R + P CCPS + +M KCW + KRP E+ Sbjct: 335 SYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEI 392
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 62.8 bits (151), Expect = 1e-09 Identities = 44/128 (34%), Positives = 62/128 (48%), Gaps = 3/128 (2%) Frame = -2 Query: 691 KIADFGVARV-EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 K+ADFG+ARV + + + GA + + APE + K DV+SFGI L+E+ Sbjct: 374 KVADFGLARVIDEEIYEAKLGAKFPIKWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGR 433 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV-QLMEA 341 PYP ++ A V + Q+ R P CP IM CW +P RP + + QL E Sbjct: 434 FPYPGMTNAQVLEQI-QQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTFETLSWQLEEF 492 Query: 340 LDTSKGGG 317 T G Sbjct: 493 FTTGDDAG 500
>ILK2_HUMAN (P57043) Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2)| Length = 452 Score = 62.8 bits (151), Expect = 1e-09 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 3/95 (3%) Frame = -2 Query: 613 YMAPEVLDGKPYN---RKCDVYSFGICLWEIYCCDMPYPDLSFADVSSAVVHQNLRPDIP 443 ++APE L KP + R D++SF + LWE+ ++P+ DLS ++ V + LRP IP Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIP 414 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +M+ C + +P KR D +V ++E + Sbjct: 415 PGISPHVCKLMKICMNEDPAKRSKFDMIVPILEKM 449
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 62.8 bits (151), Expect = 1e-09 Identities = 43/132 (32%), Positives = 67/132 (50%), Gaps = 4/132 (3%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE ++ + K DV+SFGI L EI Sbjct: 378 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR 437 Query: 517 MPYPDLSFADVSSAVV--HQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ +V + ++ +RPD CP ++M CW P+ RP D + +++ Sbjct: 438 IPYPGMTNPEVIQNLERGYRMVRPDN---CPEELYHLMMLCWKERPEDRPTFDYLRSVLD 494 Query: 343 ALDTSKGGGMIP 308 T+ G P Sbjct: 495 DFFTATEGQYQP 506
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 62.8 bits (151), Expect = 1e-09 Identities = 38/115 (33%), Positives = 55/115 (47%), Gaps = 3/115 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYC-C 521 KI DFG+ R + G G L +MAPE L ++ DV+S+G+ LWE+ Sbjct: 1177 KIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLA 1236 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 PY L+ V V+ + + P CP N+MR+CW P RP E++ Sbjct: 1237 SQPYQGLTNDQVLRYVIDGGVM-ERPENCPDNLYNLMRRCWQHRPTARPTFMEII 1290
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/118 (33%), Positives = 62/118 (52%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 404 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 463 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ +V V + R P+ CP++ +M +CW +P++RP + + +E Sbjct: 464 VPYPGMNNREVLEQV-ERGYRMPCPQDCPASLHELMLQCWKKDPEERPTFEYLQAFLE 520
>NEK11_MOUSE (Q8C0Q4) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 628 Score = 62.4 bits (150), Expect = 1e-09 Identities = 36/113 (31%), Positives = 58/113 (51%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFGV+R+ + + T TGT YM+PE L + Y+ K D++S L+E+ C D Sbjct: 173 KIGDFGVSRLLMGSCELATTLTGTPHYMSPEALKHQGYDAKSDIWSLACILYEMCCLDHA 232 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + SF V +V + P +P P IM + + +P RP ++++ Sbjct: 233 FAGSSFLSVVLNIV-EGKTPSLPDRYPRELNTIMERMLNKSPSLRPSAADILK 284
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/125 (30%), Positives = 65/125 (52%), Gaps = 7/125 (5%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG------YMAPEVLDGKPYNRKCDVYSFGICLWEI 530 K++DFG++R + D T T +LG + A E + + + DV+S+GI +WE+ Sbjct: 760 KVSDFGLSRYLQDDTSDPT-YTSSLGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEV 818 Query: 529 YCC-DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 + PY +S DV +A+ Q+ R P CP+A +M CW + + RP + E+V Sbjct: 819 MSYGERPYWTMSNQDVINAI-EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVN 877 Query: 352 LMEAL 338 + + Sbjct: 878 TLRPM 882
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/130 (30%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ Sbjct: 483 KIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELM 542 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 ++PY ++ D +V + PD+ + CP A ++ C ++RP ++ Sbjct: 543 TGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQI 602 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 603 LSSIELLQHS 612
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/129 (30%), Positives = 64/129 (49%), Gaps = 5/129 (3%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + A + +MA E L + + K DV+SFG+ +WE+ Sbjct: 201 KVADFGLARDVFGKEYYSIRQHRHAKLPVRWMALESLQTQKFTTKSDVWSFGVLMWELLT 260 Query: 523 CDM-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLM 347 PYP++ D++ ++ P P+ CP +M CW P++RP +V + Sbjct: 261 RGASPYPEVDPYDMARYLLRGRRLPQ-PQPCPDTLYGVMLSCWAPTPEERPSFSGLVCEL 319 Query: 346 EALDTSKGG 320 E + S G Sbjct: 320 ERVLASLEG 328
>MOS_XENLA (P12965) Serine/threonine-protein kinase mos (EC 2.7.11.1)| (pp39-mos) Length = 359 Score = 62.0 bits (149), Expect = 2e-09 Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 14/130 (10%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGAT---------GTLGYMAPEVLDGKPYNRKCDVYSFGICL 539 KI DFG ++ + + G GT + APE+L G+P K D+YSF I L Sbjct: 204 KIGDFGCSQRLREGDEAAGGEPCCTQLRHVGGTYTHRAPELLKGEPVTAKADIYSFAITL 263 Query: 538 WEIYCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCP-----SAFANIMRKCWDGNPDKRP 374 W++ ++PY V AVV +LRP++ A I++ CW P +RP Sbjct: 264 WQMVSRELPYTG-DRQCVLYAVVAYDLRPEMGPLFSHTEEGRAARTIVQSCWAARPQERP 322 Query: 373 DMDEVVQLME 344 + +++++ +E Sbjct: 323 NAEQLLERLE 332
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/117 (32%), Positives = 58/117 (49%), Gaps = 5/117 (4%) Frame = -2 Query: 691 KIADFGVAR----VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYC 524 K+ADFG+AR E + + A + +MA E L + K DV+SFG+ LWE+ Sbjct: 1200 KVADFGLARGVLDKEYYSVRQHRHARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLT 1259 Query: 523 CDMP-YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVV 356 P YP + D+S + P P CP + ++M +CW+ +P RP +V Sbjct: 1260 RGAPPYPHIDPFDLSHFLAQGRRLPQ-PEYCPDSLYHVMLRCWEADPAARPTFRALV 1315
>RAF1_HUMAN (P04049) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Raf-1) (C-RAF) (cRaf) Length = 648 Score = 62.0 bits (149), Expect = 2e-09 Identities = 39/130 (30%), Positives = 71/130 (54%), Gaps = 9/130 (6%) Frame = -2 Query: 691 KIADFGVARVEAQ--NPKDMTGATGTLGYMAPEVL---DGKPYNRKCDVYSFGICLWEIY 527 KI DFG+A V+++ + + TG++ +MAPEV+ D P++ + DVYS+GI L+E+ Sbjct: 483 KIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELM 542 Query: 526 CCDMPYPDLSFADVSSAVVHQN-LRPDIPRC---CPSAFANIMRKCWDGNPDKRPDMDEV 359 ++PY ++ D +V + PD+ + CP A ++ C ++RP ++ Sbjct: 543 TGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQI 602 Query: 358 VQLMEALDTS 329 + +E L S Sbjct: 603 LSSIELLQHS 612
>NEK11_MACFA (Q8WNU8) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 637 Score = 62.0 bits (149), Expect = 2e-09 Identities = 35/114 (30%), Positives = 57/114 (50%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFGV+R+ + T TGT YM+PE L + Y+ K D++S L+E+ C + Sbjct: 172 KIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHA 231 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQL 350 + +F + +V + P +P P IM + NP RP E++++ Sbjct: 232 FAGSNFLSIVLKIVEGD-TPSLPERYPKELNTIMESMLNKNPSLRPSAIEILKI 284
>CSF1R_MOUSE (P09581) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 977 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR + N A + +MAPE + Y + DV+S+GI LWEI+ Sbjct: 791 KIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLG 850 Query: 517 M-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PYP + + +V + P P +IM+ CWD P +RP ++ L++ Sbjct: 851 LNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQ 909
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 61.6 bits (148), Expect = 2e-09 Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 403 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGR 462 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ +V V + R P CP + ++M +CW P++RP + + +E Sbjct: 463 VPYPGMNNREVLEQV-ERGYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLE 519
>EGL15_CAEEL (Q10656) Myoblast growth factor receptor egl-15 precursor (EC| 2.7.10.1) (Egg-laying defective protein 15) Length = 1040 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KI+DFG++R N G L +MA E LD Y + DV+S+G+ LWEI Sbjct: 812 KISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLLWEIMTLG 871 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PYP ++ ++ A + + R + P CP ++M CW ++RP +V ++ Sbjct: 872 GTPYPTIAMPEL-YANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLD 929
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 3/116 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMT--GATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR ++P + A L +MAPE + + Y + DV+SFG+ LWEI+ Sbjct: 1041 KICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLG 1100 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ 353 PYP + + + + R P M CW +P++RP E+V+ Sbjct: 1101 ASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPSFSELVE 1156
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 61.6 bits (148), Expect = 2e-09 Identities = 44/148 (29%), Positives = 67/148 (45%), Gaps = 12/148 (8%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWE-IYCC 521 KI DFG+ R + G G L +MAPE L + DV+S+G+ +WE + Sbjct: 1188 KIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLA 1247 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQ-LME 344 PY LS +V + + ++P CP+ A +M+ CW P++RP +++ L+ Sbjct: 1248 AQPYQGLSNEEVVKFISDGYIM-ELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYLLP 1306 Query: 343 ALDTS--------KGGGMIPDGQSSGCL 284 L S GG DG G L Sbjct: 1307 KLKPSFEKVSYFFTSGGGHTDGAGEGTL 1334
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 3/125 (2%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ DFG++R +E + + +MAPE ++ + + DV+ FG+C+WEI + Sbjct: 574 KLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGV 633 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEA 341 P+ + DV + + P P C P+ + ++M KCW +P +RP E+ QL Sbjct: 634 KPFQGVKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTI 692 Query: 340 LDTSK 326 L+ K Sbjct: 693 LEEEK 697
>TOR_DROME (P18475) Tyrosine-protein kinase receptor torso precursor (EC| 2.7.10.1) Length = 923 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/110 (36%), Positives = 59/110 (53%), Gaps = 4/110 (3%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 KIADFG++R V +N +G +G L ++A E L + Y + DV+SFG+ L+EI Sbjct: 756 KIADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTL 815 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP 374 MPYP +S +D+ ++ Q R P C ++M CW P RP Sbjct: 816 GGMPYPSVSPSDLLQ-LLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRP 864
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIY-CC 521 KI DFG+ R + G G L +MAPE L + DV+SFG+ LWEI Sbjct: 1130 KIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLA 1189 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY LS V V+ + ++ CP +M +CW NP RP ++ ++ Sbjct: 1190 EQPYQGLSNEQVLKFVMDGGVLEEL-EGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQ 1247
>PGFRA_HUMAN (P16234) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) (CD140a antigen) Length = 1089 Score = 61.2 bits (147), Expect = 3e-09 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR + ++ + L +MAPE + Y DV+S+GI LWEI+ Sbjct: 833 KICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLG 892 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + + R P S IM KCW+ P+KRP + +++E Sbjct: 893 GTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVEN 952 Query: 340 L 338 L Sbjct: 953 L 953
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIY-CC 521 KI DFG+ R + G G L +MAPE L + DV+SFG+ LWEI Sbjct: 1130 KIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLA 1189 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PY LS V V+ + ++ CP +M CW NP RP +++ ++ Sbjct: 1190 EQPYQGLSNEQVLKFVMDGGVLEEL-EDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQ 1247
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 61.2 bits (147), Expect = 3e-09 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCC- 521 KI DFG+AR + ++ + L +MAPE + Y DV+SFGI LWEI+ Sbjct: 833 KICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSFGILLWEIFSLG 892 Query: 520 DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 PYP + + R P +IM KCW+ P+KRP + ++E+ Sbjct: 893 GTPYPGMIVDSTFYNKIKSGYRMAKPDHATHEVYDIMVKCWNSEPEKRPSFRHLSDIVES 952 Query: 340 L 338 L Sbjct: 953 L 953
>NEK11_HUMAN (Q8NG66) Serine/threonine-protein kinase Nek11 (EC 2.7.11.1)| (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11) Length = 645 Score = 61.2 bits (147), Expect = 3e-09 Identities = 35/114 (30%), Positives = 57/114 (50%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDMP 512 KI DFGV+R+ + T TGT YM+PE L + Y+ K D++S L+E+ C + Sbjct: 172 KIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHA 231 Query: 511 YPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQL 350 + +F + +V + P +P P IM + NP RP E++++ Sbjct: 232 FAGSNFLSIVLKIVEGD-TPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKI 284
>MOS_MSVMO (P00538) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 374 Score = 60.8 bits (146), Expect = 4e-09 Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 13/136 (9%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGAT-------GTLGYMAPEVLDGKPYNRKCDVYSFGICLWE 533 KI+DFG + Q +D+ G GT + APE+L G+ K D+YSFGI LW+ Sbjct: 244 KISDFGCS----QKLQDLRGRQASPPHIGGTYTHQAPEILKGEIATPKADIYSFGITLWQ 299 Query: 532 IYCCDMPYPDLSFADVSSAVVHQNLRPDI------PRCCPSAFANIMRKCWDGNPDKRPD 371 + ++PY V AVV NLRP + A NI++ CW+ +RP Sbjct: 300 MTTREVPYSG-EPQYVQYAVVAYNLRPSLAGAVFTASLTGKALQNIIQSCWEARGLQRPS 358 Query: 370 MDEVVQLMEALDTSKG 323 + + + ++A + G Sbjct: 359 AELLQRDLKAFRGTLG 374
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI E+ Sbjct: 408 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR 467 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP + +V V + R P+ CP + +M CW +PD+RP + + +E Sbjct: 468 VPYPGMVNREVLEQV-ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 524
>CSF1R_RAT (Q00495) Macrophage colony-stimulating factor 1 receptor precursor| (CSF-1-R) (EC 2.7.10.1) (Fms proto-oncogene) (c-fms) Length = 978 Score = 60.8 bits (146), Expect = 4e-09 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 3/119 (2%) Frame = -2 Query: 691 KIADFGVAR--VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG+AR + N A + +MAPE + Y + DV+S+GI LWEI+ Sbjct: 791 KIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESILYCVYTVQSDVWSYGILLWEIFSLG 850 Query: 517 M-PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 + PYP + + +V + P P +IM+ CWD P +RP ++ L++ Sbjct: 851 LNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQ 909
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 60.8 bits (146), Expect = 4e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 3/125 (2%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ DFG++R +E + + +MAPE ++ + + DV+ FG+C+WEI + Sbjct: 561 KLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGV 620 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEA 341 P+ + DV + + P P C P+ + ++M KCW +P +RP E+ QL Sbjct: 621 KPFQGVKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTI 679 Query: 340 LDTSK 326 L+ K Sbjct: 680 LEEEK 684
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 60.8 bits (146), Expect = 4e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 3/125 (2%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ DFG++R +E + + +MAPE ++ + + DV+ FG+C+WEI + Sbjct: 561 KLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGV 620 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEA 341 P+ + DV + + P P C P+ + ++M KCW +P +RP E+ QL Sbjct: 621 KPFQGVKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTI 679 Query: 340 LDTSK 326 L+ K Sbjct: 680 LEEEK 684
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 60.8 bits (146), Expect = 4e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 3/125 (2%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ DFG++R +E + + +MAPE ++ + + DV+ FG+C+WEI + Sbjct: 599 KLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGV 658 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEA 341 P+ + DV + + P P C P+ + ++M KCW +P +RP E+ QL Sbjct: 659 KPFQGVKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTI 717 Query: 340 LDTSK 326 L+ K Sbjct: 718 LEEEK 722
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 60.8 bits (146), Expect = 4e-09 Identities = 37/125 (29%), Positives = 64/125 (51%), Gaps = 3/125 (2%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ DFG++R +E + + +MAPE ++ + + DV+ FG+C+WEI + Sbjct: 561 KLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGV 620 Query: 514 -PYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEV-VQLMEA 341 P+ + DV + + P P C P+ + ++M KCW +P +RP E+ QL Sbjct: 621 KPFQGVKNNDVIGRIENGERLPMPPNCPPTLY-SLMTKCWAYDPSRRPRFTELKAQLSTI 679 Query: 340 LDTSK 326 L+ K Sbjct: 680 LEEEK 684
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI E+ Sbjct: 410 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR 469 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP + +V V + R P+ CP + +M CW +PD+RP + + +E Sbjct: 470 VPYPGMVNREVLEQV-ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 526
>NTRK3_CHICK (Q91044) NT-3 growth factor receptor precursor (EC 2.7.10.1)| (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (Trk-C) Length = 827 Score = 60.5 bits (145), Expect = 5e-09 Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 3/121 (2%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGATGTLG--YMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD 518 KI DFG++R G L +M PE + + + + DV+SFG+ LWEI+ Sbjct: 696 KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYG 755 Query: 517 -MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEA 341 P+ LS +V + + + PR CP +IM CW P +R ++ E+ +++ A Sbjct: 756 KQPWFQLSNTEVIECITQGRVL-ERPRVCPKEVYDIMLGCWQREPQQRLNIKEIYKILHA 814 Query: 340 L 338 L Sbjct: 815 L 815
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 60.5 bits (145), Expect = 5e-09 Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 404 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 463 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ +V V + R P+ CP + +M CW +P++RP + + +E Sbjct: 464 VPYPGMNNREVLEQV-ERGYRMPCPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLE 520
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 60.5 bits (145), Expect = 5e-09 Identities = 39/118 (33%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI L E+ Sbjct: 404 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR 463 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ +V V + R P+ CP + +M CW +P++RP + + +E Sbjct: 464 VPYPGMNNREVLEQV-ERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLE 520
>STK_HYDAT (P17713) Tyrosine-protein kinase STK (EC 2.7.10.2) (P57-STK)| Length = 509 Score = 60.5 bits (145), Expect = 5e-09 Identities = 41/118 (34%), Positives = 61/118 (51%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 K+ADFG+AR +E GA + + APE + K DV+SFGI + EI Sbjct: 375 KVADFGLARLIEDDEYTAHEGAKFPIKWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGR 434 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP ++ A + A V + R I CP NIM + W+ +P+ RP D + ++E Sbjct: 435 IPYPGMTNAQ-TIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTFDYLQGVLE 491
>YES_CANFA (Q28923) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 538 Score = 60.5 bits (145), Expect = 5e-09 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 2/118 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E GA + + APE + K DV+SFGI E+ Sbjct: 406 KIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGR 465 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 +PYP + +V V + R P+ CP + +M CW +PD+RP + + +E Sbjct: 466 VPYPGMVNREVLEQV-ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 522
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 60.5 bits (145), Expect = 5e-09 Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 1/88 (1%) Frame = -2 Query: 619 LGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC-DMPYPDLSFADVSSAVVHQNLRPDIP 443 L +M PE + ++ K DV+SFG+ +WE++ +MPY L+ +V + + + P Sbjct: 951 LRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQP 1010 Query: 442 RCCPSAFANIMRKCWDGNPDKRPDMDEV 359 CPS +M++CW +P RP E+ Sbjct: 1011 EGCPSRLTKLMQRCWAPSPKDRPSFSEL 1038
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 60.5 bits (145), Expect = 5e-09 Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 15/132 (11%) Frame = -2 Query: 688 IADFGVARV---EAQNPKDMTG-----------ATGTLGYMAPEVLDGKPYNRKCDVYSF 551 +ADFG+AR+ E P+ + G +MAPE+++G+ Y+ K D++SF Sbjct: 483 VADFGLARLMVDEKNQPEHLQNLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDIFSF 542 Query: 550 GICLWEIYCCDMPYPD-LSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRP 374 GI L EI PD L V L P CP +F I C D +P+KRP Sbjct: 543 GIVLCEIIGRVSADPDYLPRTTDFGLNVRGFLERYCPPACPPSFFPIAACCCDLDPEKRP 602 Query: 373 DMDEVVQLMEAL 338 ++ Q +E L Sbjct: 603 SFSKLEQWLETL 614
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 60.5 bits (145), Expect = 5e-09 Identities = 35/123 (28%), Positives = 69/123 (56%), Gaps = 4/123 (3%) Frame = -2 Query: 691 KIADFGVARV---EAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCC 521 K+ADFG+AR+ + +P +G+ + + APE + + +++K DV+SFGI L+E++ Sbjct: 369 KVADFGLARLLKDDVYSPS--SGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTY 426 Query: 520 -DMPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLME 344 PY ++ + + + R P CP+ +M +CW G+P++RP + + + Sbjct: 427 GQCPYEGMTNHETLQQ-ISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFAILREKLN 485 Query: 343 ALD 335 A++ Sbjct: 486 AIN 488
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 60.1 bits (144), Expect = 6e-09 Identities = 40/123 (32%), Positives = 61/123 (49%), Gaps = 2/123 (1%) Frame = -2 Query: 691 KIADFGVAR-VEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCD- 518 KIADFG+AR +E G + + APE + K DV+SFGI L E+ Sbjct: 385 KIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGR 444 Query: 517 MPYPDLSFADVSSAVVHQNLRPDIPRCCPSAFANIMRKCWDGNPDKRPDMDEVVQLMEAL 338 +PYP ++ +V V H P P CP++ +M + W +P++RP + + +E Sbjct: 445 VPYPGMNNREVLEQVEHGYHMP-CPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDY 503 Query: 337 DTS 329 TS Sbjct: 504 FTS 506
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 60.1 bits (144), Expect = 6e-09 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 11/117 (9%) Frame = -2 Query: 691 KIADFGVARVEA---QNPKDMTGATGTLGYMAPEVLDGKP--YNRKCDVYSFGICLWEIY 527 KI+DFG+A+ + M G GT+ Y+ PE + K ++ K DVYSF I +W + Sbjct: 158 KISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVL 217 Query: 526 CCDMPYPDLSFADVSSAVVHQNLRPDIPRCCP------SAFANIMRKCWDGNPDKRP 374 P+ D V + RP++P C S +M++CW G+P RP Sbjct: 218 TQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRP 274
>MOS_MSVMM (P00537) Serine/threonine-protein kinase transforming protein mos| (EC 2.7.11.1) Length = 376 Score = 60.1 bits (144), Expect = 6e-09 Identities = 43/133 (32%), Positives = 66/133 (49%), Gaps = 12/133 (9%) Frame = -2 Query: 691 KIADFGVA------RVEAQNPKDMTGATGTLGYMAPEVLDGKPYNRKCDVYSFGICLWEI 530 KI+DFG + R +P + G T + APE+L G+ K D+YSFGI LW++ Sbjct: 244 KISDFGCSQKLQDLRCRQASPHHIGG---TYTHQAPEILKGEIATPKADIYSFGITLWQM 300 Query: 529 YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPSA------FANIMRKCWDGNPDKRPDM 368 ++PY V AVV NLRP + +A NI++ CW+ +RP Sbjct: 301 TTREVPYSG-EPQYVQYAVVAYNLRPSLAGAVFTASLTGKTLQNIIQSCWEARALQRPGA 359 Query: 367 DEVVQLMEALDTS 329 + + + ++AL S Sbjct: 360 ELLQRDLKALADS 372
>PKN6_MYXXA (P54738) Serine/threonine-protein kinase pkn6 (EC 2.7.11.1)| Length = 710 Score = 60.1 bits (144), Expect = 6e-09 Identities = 30/90 (33%), Positives = 49/90 (54%), Gaps = 7/90 (7%) Frame = -2 Query: 691 KIADFGVARVEAQNPKDMTGAT-GTLGYMAPEVLDGKPYNRKCDVYSFGICLWEIYCCDM 515 K+ DFG+A+V Q + +TG G + YM PE L K +R+ DVY+ G+ L+E+ Sbjct: 158 KVVDFGIAKVAGQGHRTLTGVVKGKVAYMPPEQLQAKAMDRRVDVYALGVVLYELLTGKR 217 Query: 514 PYPDLSFADVSSAVVHQNL------RPDIP 443 P+ + V A++ ++ RPD+P Sbjct: 218 PFDATTDVSVMQAILFESFIPVSARRPDVP 247
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 60.1 bits (144), Expect = 6e-09 Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 12/118 (10%) Frame = -2 Query: 691 KIADFGVARVEAQNPK----DMTGATGTLGYMAPEVL--DGKPYNRKCDVYSFGICLWEI 530 KI+DFG+++ Q+ + + + GTL Y+ PE+ + K + DVYSF I +WEI Sbjct: 172 KISDFGLSKWMEQSTQKQYIERSALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEI 231 Query: 529 YCCDMPYPDLSFADVSSAVVHQNLRPDIPRCCPS------AFANIMRKCWDGNPDKRP 374 PY L+ + V +RP + N+M++CWD +P KRP Sbjct: 232 LTQKKPYAGLNMMTIIIRVA-AGMRPSLQDVSDEWPEEVHQMVNLMKRCWDQDPKKRP 288 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 107,056,290 Number of Sequences: 219361 Number of extensions: 2379657 Number of successful extensions: 9289 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 8084 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8604 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 6856295237 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
