ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal10o23 |
|---|---|
| Clone Library Name | barley_pub |
>BAK1_ARATH (Q94F62) BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1| precursor (EC 2.7.11.1) (BRI1-associated receptor kinase 1) (Somatic embryogenesis receptor-like kinase 3) Length = 615 Score = 73.2 bits (178), Expect = 7e-13 Identities = 44/119 (36%), Positives = 73/119 (61%), Gaps = 4/119 (3%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPS-VENQDEVYLPE 468 TA RGT+G+IAPE S G S K+DV+ +G+++LE+++G+R D + + N D+V L + Sbjct: 450 TAVRGTIGHIAPEYLST--GKSSEKTDVFGYGVMLLELITGQRAFDLARLANDDDVMLLD 507 Query: 467 WIYQKVISGHDWELTLEMTAEDK---EKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTG 300 W+ + ++ E +++ + E++ QL V L C Q +P RP M++VV ML G Sbjct: 508 WV-KGLLKEKKLEALVDVDLQGNYKDEEVEQLIQVALLCTQSSPMERPKMSEVVRMLEG 565
>CRI4_MAIZE (O24585) Putative receptor protein kinase CRINKLY4 precursor (EC| 2.7.11.1) Length = 901 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/122 (33%), Positives = 68/122 (55%), Gaps = 2/122 (1%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT+GY+ PE Y ++ ++ KSDVYSFG+++LE++SGR+ D E E + EW Sbjct: 673 GTLGYLDPEYYRLHY--LTTKSDVYSFGVVLLEILSGRKAIDMQFE---EGNIVEWAVPL 727 Query: 452 VISGHDWELTLEMTA--EDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQI 279 + +G + + + + D E +++++ V C++ K+RPSM KV L L L Sbjct: 728 IKAGDIFAILDPVLSPPSDLEALKKIASVACKCVRMRGKDRPSMDKVTTALEHALALLMG 787 Query: 278 PP 273 P Sbjct: 788 SP 789
>RLK5_ARATH (P47735) Receptor-like protein kinase 5 precursor (EC 2.7.11.1)| Length = 999 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/116 (34%), Positives = 72/116 (62%), Gaps = 2/116 (1%) Frame = -2 Query: 647 LTAARGTMGYIAPE-LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLP 471 ++ G+ GYIAPE +Y+ V+ KSD+YSFG+++LE+V+G++ +D + ++D + Sbjct: 855 MSGIAGSCGYIAPEYVYTLR---VNEKSDIYSFGVVLLELVTGKQPTDSELGDKD---MA 908 Query: 470 EWIYQKVIS-GHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 +W+ + G + + ++ + KE++ ++ +GL C P NRPSM KVV ML Sbjct: 909 KWVCTALDKCGLEPVIDPKLDLKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIML 964
>APK1A_ARATH (Q06548) Protein kinase APK1A, chloroplast precursor (EC 2.7.11.1)| Length = 410 Score = 58.9 bits (141), Expect = 1e-08 Identities = 42/123 (34%), Positives = 69/123 (56%), Gaps = 3/123 (2%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D+S V+ T GT GY APE + G ++ KSDVYSFG+++LE++SGRR D + Sbjct: 232 DKSHVS-TRVMGTHGYAAPEYLAT--GHLTTKSDVYSFGVVLLELLSGRRAVDKN-RPSG 287 Query: 485 EVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQ---LSIVGLWCIQWNPKNRPSMTKVV 315 E L EW +++ ++ +D+ M + ++ + L C+ K RP+M++VV Sbjct: 288 ERNLVEWAKPYLVNKRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVV 347 Query: 314 NML 306 + L Sbjct: 348 SHL 350
>TMK1_ARATH (P43298) Putative receptor protein kinase TMK1 precursor (EC| 2.7.11.1) Length = 942 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 5/123 (4%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T GT GY+APE G V+ K DVYSFG++++E+++GR++ D S + ++ ++L W Sbjct: 751 TRIAGTFGYLAPEYAVT--GRVTTKVDVYSFGVILMELITGRKSLDES-QPEESIHLVSW 807 Query: 464 IYQKVISGH-----DWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTG 300 + I+ + T+++ E + ++ + C P RP M VN+L+ Sbjct: 808 FKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSS 867 Query: 299 RLQ 291 ++ Sbjct: 868 LVE 870
>EXS_ARATH (Q9LYN8) Leucine-rich repeat receptor protein kinase EXS precursor| (EC 2.7.11.1) (Extra sporogenous cells protein) (EXCESS MICROSPOROCYTES1 protein) Length = 1192 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/115 (31%), Positives = 59/115 (51%), Gaps = 2/115 (1%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T GT GYI PE Y ++ + K DVYSFG+++LE+V+G+ + P + + L W Sbjct: 1077 TVIAGTFGYIPPE-YGQSARATT-KGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGW 1134 Query: 464 IYQKVISGHDWEL--TLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 QK+ G ++ L ++ K +L + + C+ P RP+M V+ L Sbjct: 1135 AIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKAL 1189
>NAK_ARATH (P43293) Probable serine/threonine-protein kinase NAK (EC 2.7.11.1)| Length = 389 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T GT GY APE + G +S KSDVYSFG+++LE++SGRR D + + E L +W Sbjct: 238 TRVMGTQGYAAPEYLAT--GHLSVKSDVYSFGVVLLELLSGRRAIDKN-QPVGEHNLVDW 294 Query: 464 IYQKVISGHDWELTLEMTAEDKEKMR---QLSIVGLWCIQWNPKNRPSMTKVVNML 306 + + ++ + + + +++++ L CI + K+RP+M ++V + Sbjct: 295 ARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTM 350
>APK1B_ARATH (P46573) Protein kinase APK1B, chloroplast precursor (EC 2.7.11.1)| Length = 412 Score = 57.0 bits (136), Expect = 5e-08 Identities = 41/123 (33%), Positives = 68/123 (55%), Gaps = 3/123 (2%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D+S V+ T GT GY APE + G ++ KSDVYS+G+++LE++SGRR D + Sbjct: 233 DKSHVS-TRIMGTYGYAAPEYLAT--GHLTTKSDVYSYGVVLLEVLSGRRAVDKN-RPPG 288 Query: 485 EVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQ---LSIVGLWCIQWNPKNRPSMTKVV 315 E L EW + + ++ +D+ M + ++ + L C+ + K RP+M +VV Sbjct: 289 EQKLVEWARPLLANKRKLFRVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVV 348 Query: 314 NML 306 + L Sbjct: 349 SHL 351
>CX32_ARATH (P27450) Probable serine/threonine-protein kinase Cx32, chloroplast| precursor (EC 2.7.11.1) Length = 419 Score = 57.0 bits (136), Expect = 5e-08 Identities = 45/153 (29%), Positives = 82/153 (53%), Gaps = 8/153 (5%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 A ++S VT T GT GY APE + G + KSDV++FG+++LE+++G + Sbjct: 245 ADEKSHVT-TRIMGTYGYAAPEYMAT--GHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPR 301 Query: 491 QDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMR---QLSIVGLWCIQWNPKNRPSMTK 321 E L +W+ ++ + H + ++ + + + +++ + L CI+ +PKNRP M + Sbjct: 302 GQES-LVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKE 360 Query: 320 VVNMLTGRLQNLQIPP-----KPFVSSDNRPMP 237 VV +L +Q L + P K V++ +R P Sbjct: 361 VVEVLE-HIQGLNVVPNRSSTKQAVANSSRSSP 392
>SRK6_BRAOE (Q09092) Putative serine/threonine-protein kinase receptor precursor| (EC 2.7.11.1) (S-receptor kinase) (SRK) Length = 849 Score = 56.2 bits (134), Expect = 9e-08 Identities = 43/144 (29%), Positives = 72/144 (50%), Gaps = 10/144 (6%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 RD++ GT GY++PE +G S KSDV+SFG++VLE+VSG++N N Sbjct: 680 RDETEANTMKVVGTYGYMSPEYAM--YGIFSEKSDVFSFGVIVLEIVSGKKNR--GFYNL 735 Query: 488 D-EVYLPEWIYQKVISGHDWE---------LTLEMTAEDKEKMRQLSIVGLWCIQWNPKN 339 D E L +++ + G E L+ + + +++ + +GL C+Q ++ Sbjct: 736 DYENDLLSYVWSRWKEGRALEIVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEH 795 Query: 338 RPSMTKVVNMLTGRLQNLQIPPKP 267 RP+M+ VV M + P P Sbjct: 796 RPAMSSVVWMFGSEATEIPQPKPP 819
>RLCK7_ARATH (Q9LQQ8) Probable serine/threonine-protein kinase RLCKVII (EC| 2.7.11.1) Length = 423 Score = 55.5 bits (132), Expect = 1e-07 Identities = 39/137 (28%), Positives = 67/137 (48%), Gaps = 3/137 (2%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T GT GY AP+ Y+ G +++KSD+YSFG+++LE+++GR+ D + +D+ L W Sbjct: 265 TRVMGTYGYCAPD-YAMT-GQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQ-NLVGW 321 Query: 464 IYQKVISGHDWELTLEMTAEDKEKMR---QLSIVGLWCIQWNPKNRPSMTKVVNMLTGRL 294 ++ ++ + + +R Q + C+Q P RP ++ VV L Sbjct: 322 ARPLFKDRRNFPKMVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLA 381 Query: 293 QNLQIPPKPFVSSDNRP 243 + P P SS P Sbjct: 382 SSKYDPNSPSSSSGKNP 398
>PSKR_DAUCA (Q8LPB4) Phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1021 Score = 54.7 bits (130), Expect = 3e-07 Identities = 36/112 (32%), Positives = 60/112 (53%), Gaps = 3/112 (2%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT+GYI PE + +YK DVYSFG+++LE+++GRR D + + L W+ Q Sbjct: 907 GTLGYIPPEYGQASVA--TYKGDVYSFGVVLLELLTGRRPMD-VCKPRGSRDLISWVLQM 963 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIV---GLWCIQWNPKNRPSMTKVVNML 306 + E+ + DK+ ++ +V C+ NPK RP+ ++V+ L Sbjct: 964 KTEKRESEI-FDPFIYDKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWL 1014
>KPEL_DROME (Q05652) Probable serine/threonine-protein kinase pelle (EC| 2.7.11.1) Length = 501 Score = 52.8 bits (125), Expect = 1e-06 Identities = 38/119 (31%), Positives = 63/119 (52%), Gaps = 4/119 (3%) Frame = -2 Query: 659 SIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 ++V + GT Y+ PE RNF +S DVYSFG+++LE+ +GR+ +D EN+ + Sbjct: 377 AVVEVNKVFGTKIYLPPEF--RNFRQLSTGVDVYSFGIVLLEVFTGRQVTDRVPENETKK 434 Query: 479 YLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSI----VGLWCIQWNPKNRPSMTKVV 315 L +++ Q+ EL + A K + + GL C +P++RPSM V+ Sbjct: 435 NLLDYVKQQWRQNR-MELLEKHLAAPMGKELDMCMCAIEAGLHCTALDPQDRPSMNAVL 492
>PSKR_ARATH (Q9ZVR7) Putative phytosulfokine receptor precursor (EC 2.7.11.1)| (Phytosulfokine LRR receptor kinase) Length = 1008 Score = 51.6 bits (122), Expect = 2e-06 Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 3/112 (2%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT+GYI PE + +YK DVYSFG+++LE+++ +R D + + L W+ + Sbjct: 898 GTLGYIPPEYGQASVA--TYKGDVYSFGVVLLELLTDKRPVD-MCKPKGCRDLISWVVKM 954 Query: 452 VISGHDWEL---TLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 E+ + DKE R L I L C+ NPK RP+ ++V+ L Sbjct: 955 KHESRASEVFDPLIYSKENDKEMFRVLEIACL-CLSENPKQRPTTQQLVSWL 1005
>BRL3_ARATH (Q9LJF3) Serine/threonine-protein kinase BRI1-like 3 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 3) Length = 1164 Score = 50.8 bits (120), Expect = 4e-06 Identities = 38/125 (30%), Positives = 67/125 (53%), Gaps = 4/125 (3%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDE--V 480 ++++ GT GY+ PE Y ++F + K DVYS+G+++LE++SG++ DP +D V Sbjct: 1017 LSVSTLAGTPGYVPPEYY-QSFRCTA-KGDVYSYGVILLELLSGKKPIDPEEFGEDNNLV 1074 Query: 479 YLPEWIYQKVISGH--DWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 + +Y++ D EL + + D E + L I C+ P RP+M +V+ M Sbjct: 1075 GWAKQLYREKRGAEILDPELVTDKSG-DVELLHYLKIAS-QCLDDRPFKRPTMIQVMTMF 1132 Query: 305 TGRLQ 291 +Q Sbjct: 1133 KELVQ 1137
>BRL2_ARATH (Q9ZPS9) Serine/threonine-protein kinase BRI1-like 2 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 2) (Protein VASCULAR HIGHWAY 1) Length = 1143 Score = 50.4 bits (119), Expect = 5e-06 Identities = 43/134 (32%), Positives = 66/134 (49%), Gaps = 18/134 (13%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYL 474 ++++ GT GY+ PE Y ++F + K DVYS G+++LE++SG+R +D E + L Sbjct: 998 LSVSTLAGTPGYVPPEYY-QSFRCTA-KGDVYSIGVVMLEILSGKRPTDK--EEFGDTNL 1053 Query: 473 PEWIYQKVISGH-----DWELTLEMTAED-------------KEKMRQLSIVGLWCIQWN 348 W K G D +L E ++E KE +R L I L C+ Sbjct: 1054 VGWSKMKAREGKHMEVIDEDLLKEGSSESLNEKEGFEGGVIVKEMLRYLEI-ALRCVDDF 1112 Query: 347 PKNRPSMTKVVNML 306 P RP+M +VV L Sbjct: 1113 PSKRPNMLQVVASL 1126
>CLV1_ARATH (Q9SYQ8) Receptor protein kinase CLAVATA1 precursor (EC 2.7.11.1)| Length = 980 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 8/134 (5%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPE 468 +++ G+ GYIAPE Y+ V KSDVYSFG+++LE+++G++ P E + V + Sbjct: 851 MSSIAGSYGYIAPE-YAYTLK-VDEKSDVYSFGVVLLELIAGKK---PVGEFGEGVDIVR 905 Query: 467 WI---YQKVISGHDWELTL-----EMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 W+ +++ D + + +T + + + + C++ RP+M +VV+ Sbjct: 906 WVRNTEEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVH 965 Query: 311 MLTGRLQNLQIPPK 270 MLT PPK Sbjct: 966 MLTN-------PPK 972
>BRI1_ARATH (O22476) BRASSINOSTEROID INSENSITIVE 1 precursor (EC 2.7.11.1)| (AtBRI1) (Brassinosteroid LRR receptor kinase) Length = 1196 Score = 49.3 bits (116), Expect = 1e-05 Identities = 38/120 (31%), Positives = 67/120 (55%), Gaps = 5/120 (4%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSD-PSVENQDEVY 477 ++++ GT GY+ PE Y ++F S K DVYS+G+++LE+++G+R +D P + + Sbjct: 1041 LSVSTLAGTPGYVPPEYY-QSFR-CSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNN--- 1095 Query: 476 LPEWIYQ----KVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNM 309 L W+ Q ++ D EL E A + E ++ L V + C+ RP+M +V+ M Sbjct: 1096 LVGWVKQHAKLRISDVFDPELMKEDPALEIELLQHLK-VAVACLDDRAWRRPTMVQVMAM 1154
>RPK1_IPONI (P93194) Receptor-like protein kinase precursor (EC 2.7.11.1)| Length = 1109 Score = 48.5 bits (114), Expect = 2e-05 Identities = 37/133 (27%), Positives = 69/133 (51%), Gaps = 12/133 (9%) Frame = -2 Query: 665 DQSIVTLTA--ARGTMGYIAPELYSRNFGGV-SYKSDVYSFGMLVLEMVSGRRNSDPSVE 495 DQS ++ + +GT+GY+APE F V S +SDVYS+G+++LE+++ ++ DPS Sbjct: 968 DQSATSIPSNTVQGTIGYMAPE---NAFTTVKSRESDVYSYGVVLLELITRKKALDPSFN 1024 Query: 494 NQDEVYLPEWI---------YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPK 342 + ++ W+ QK++ + ++ + E++ + + L C + Sbjct: 1025 GETDIV--GWVRSVWTQTGEIQKIVDPSLLDELIDSSV--MEQVTEALSLALRCAEKEVD 1080 Query: 341 NRPSMTKVVNMLT 303 RP+M VV LT Sbjct: 1081 KRPTMRDVVKQLT 1093
>BRL1_ARATH (Q9ZWC8) Serine/threonine-protein kinase BRI1-like 1 precursor (EC| 2.7.11.1) (BRASSINOSTEROID INSENSITIVE 1-like protein 1) Length = 1166 Score = 47.8 bits (112), Expect = 3e-05 Identities = 36/119 (30%), Positives = 64/119 (53%), Gaps = 4/119 (3%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDE--V 480 ++++ GT GY+ PE Y ++F + K DVYS+G+++LE++SG++ DP +D V Sbjct: 1019 LSVSTLAGTPGYVPPEYY-QSFRCTA-KGDVYSYGVILLELLSGKKPIDPGEFGEDNNLV 1076 Query: 479 YLPEWIYQKVISGH--DWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNM 309 + +Y++ D EL + + D E L I C+ P RP+M +++ M Sbjct: 1077 GWAKQLYREKRGAEILDPELVTDKSG-DVELFHYLKIAS-QCLDDRPFKRPTMIQLMAM 1133
>PBS1_ARATH (Q9FE20) Serine/threonine-protein kinase PBS1 (EC 2.7.11.1)| (AvrPphB susceptible protein 1) Length = 456 Score = 47.0 bits (110), Expect = 5e-05 Identities = 49/146 (33%), Positives = 66/146 (45%), Gaps = 6/146 (4%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D+S V+ T GT GY APE Y+ G ++ KSDVYSFG++ LE+++GR+ D + + Sbjct: 242 DKSHVS-TRVMGTYGYCAPE-YAMT-GQLTVKSDVYSFGVVFLELITGRKAIDSEMPH-G 297 Query: 485 EVYLPEWI------YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMT 324 E L W +K I D L + Q V CIQ RP + Sbjct: 298 EQNLVAWARPLFNDRRKFIKLADPRLKGRFPT---RALYQALAVASMCIQEQAATRPLIA 354 Query: 323 KVVNMLTGRLQNLQIPPKPFVSSDNR 246 VV L+ L N P S NR Sbjct: 355 DVVTALS-YLANQAYDPSKDDSRRNR 379
>IRAK4_HUMAN (Q9NWZ3) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) (NY-REN-64 antigen) Length = 460 Score = 46.6 bits (109), Expect = 7e-05 Identities = 32/109 (29%), Positives = 54/109 (49%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT Y+APE G ++ KSD+YSFG+++LE+++G D E Q + + E I + Sbjct: 350 GTTAYMAPEALR---GEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDE 406 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 + D+ + +M D + + V C+ RP + KV +L Sbjct: 407 EKTIEDY-IDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLL 454
>SIRK_ARATH (O64483) Senescence-induced receptor-like serine/threonine-protein| kinase precursor (FLG22-induced receptor-like kinase 1) Length = 876 Score = 46.6 bits (109), Expect = 7e-05 Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 4/114 (3%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ--DEVYLP 471 T G++GY+ PE YS ++ KSDVYS G+++LE+++G+ P++ + ++V++ Sbjct: 732 TVVAGSIGYLDPEYYSTR--QMNEKSDVYSLGVVLLEVITGQ----PAIASSKTEKVHIS 785 Query: 470 EWIYQKVISGHDWELTLEMTAE--DKEKMRQLSIVGLWCIQWNPKNRPSMTKVV 315 + + + +G + + E D ++S + L C + RP+M++VV Sbjct: 786 DHVRSILANGDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVV 839
>IRAK4_MOUSE (Q8R4K2) Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1)| (IRAK-4) Length = 459 Score = 46.2 bits (108), Expect = 9e-05 Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 AR V + GT Y+APE G ++ KSD+YSFG+++LE+++G D + E Sbjct: 337 ARLAQTVMTSRIVGTTAYMAPEALR---GEITPKSDIYSFGVVLLELITGLAAVDENREP 393 Query: 491 QDEVYLPEWI--YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 Q + + E I +K I + E +M+ D + + C+ RP + KV Sbjct: 394 QLLLDIKEEIEDEEKTIEDYTDE---KMSDADPASVEAMYSAASQCLHEKKNRRPDIAKV 450 Query: 317 VNML 306 +L Sbjct: 451 QQLL 454
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 2/103 (1%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT+GY+APEL+ S SDVYSFG+L+ +++GR P+ P +Y+ Sbjct: 181 GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTE--------PSLVYEA 232 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWN--PKNRPS 330 V + + E+ E + L + W+ PK+RPS Sbjct: 233 VCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPS 275
>BRI1_LYCPE (Q8L899) Systemin receptor SR160 precursor (EC 2.7.11.1)| (Brassinosteroid LRR receptor kinase) Length = 1207 Score = 45.4 bits (106), Expect = 2e-04 Identities = 35/119 (29%), Positives = 64/119 (53%), Gaps = 4/119 (3%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYL 474 ++++ GT GY+ PE Y ++F S K DVYS+G+++LE+++G++ +D + + L Sbjct: 1046 LSVSTLAGTPGYVPPEYY-QSFR-CSTKGDVYSYGVVLLELLTGKQPTDSADFGDNN--L 1101 Query: 473 PEWI----YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNM 309 W+ K+ D EL E + + E ++ L V C+ RP+M +V+ M Sbjct: 1102 VGWVKLHAKGKITDVFDRELLKEDASIEIELLQHLK-VACACLDDRHWKRPTMIQVMAM 1159
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor (EC 2.7.11.1)| (tBRI1) (Altered brassinolide sensitivity 1) (Systemin receptor SR160) Length = 1207 Score = 45.4 bits (106), Expect = 2e-04 Identities = 35/119 (29%), Positives = 64/119 (53%), Gaps = 4/119 (3%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYL 474 ++++ GT GY+ PE Y ++F S K DVYS+G+++LE+++G++ +D + + L Sbjct: 1046 LSVSTLAGTPGYVPPEYY-QSFR-CSTKGDVYSYGVVLLELLTGKQPTDSADFGDNN--L 1101 Query: 473 PEWI----YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNM 309 W+ K+ D EL E + + E ++ L V C+ RP+M +V+ M Sbjct: 1102 VGWVKLHAKGKITDVFDRELLKEDASIEIELLQHLK-VACACLDDRHWKRPTMIQVMAM 1159
>KPRO_MAIZE (P17801) Putative receptor protein kinase ZmPK1 precursor (EC| 2.7.11.1) Length = 817 Score = 44.7 bits (104), Expect = 3e-04 Identities = 27/64 (42%), Positives = 41/64 (64%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 R S ++ RGT+GYIAPE S ++ K DVYS+G+++LE+++G R S+ V Sbjct: 685 RGGSTQNVSHVRGTLGYIAPEWVSSL--PITAKVDVYSYGVVLLELLTGTRVSE-LVGGT 741 Query: 488 DEVY 477 DEV+ Sbjct: 742 DEVH 745
>NORK_PEA (Q8LKZ1) Nodulation receptor kinase precursor (EC 2.7.11.1)| Length = 924 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/39 (56%), Positives = 29/39 (74%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 RGT GY+ PE Y +S KSDV+SFG+++LE+VSGR Sbjct: 759 RGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGR 795
>NORK_MEDTR (Q8L4H4) Nodulation receptor kinase precursor (EC 2.7.11.1) (Does| not make infections protein 2) (Symbiosis receptor-like kinase) (MtSYMRK) Length = 925 Score = 44.3 bits (103), Expect = 3e-04 Identities = 22/39 (56%), Positives = 29/39 (74%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 RGT GY+ PE Y +S KSDV+SFG+++LE+VSGR Sbjct: 760 RGTAGYLDPEYYKTQ--QLSEKSDVFSFGVVLLEIVSGR 796
>M3LK7_DROME (P83104) Putative mitogen-activated protein kinase kinase kinase| 7-like (EC 2.7.11.25) Length = 393 Score = 42.0 bits (97), Expect = 0.002 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 1/114 (0%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T +GT+ Y+APE + K DVYSFG+++ E+++ R+ +EN + Y Sbjct: 164 TDMQGTLRYMAPEAIKHL--KYTAKCDVYSFGIMLWELMT-RQLPYSHLENPNSQYA--- 217 Query: 464 IYQKVISGHDWELTLEMTAED-KEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 I + + SG +L +E D E ++QL C+ NP+ RPSM ++ L Sbjct: 218 IMKAISSGE--KLPMEAVRSDCPEGIKQLMEC---CMDINPEKRPSMKEIEKFL 266
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 41.2 bits (95), Expect = 0.003 Identities = 34/130 (26%), Positives = 58/130 (44%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 RD + A+ + + APE + N S KSDV++FG+L+ E+ + + P+++ Sbjct: 518 RDDTYTAHAGAKFPIKWTAPEGLAYN--KFSTKSDVWAFGVLLWEIATYGMSPYPAIDLT 575 Query: 488 DEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNM 309 D +Y K+ G+ E E + MRQ C QW+ +RP+ + + Sbjct: 576 D-------VYHKLDKGYRMERPPGCPPEVYDLMRQ-------CWQWDATDRPTFKSIHHA 621 Query: 308 LTGRLQNLQI 279 L Q I Sbjct: 622 LEHMFQESSI 631
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 40.8 bits (94), Expect = 0.004 Identities = 21/38 (55%), Positives = 27/38 (71%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+ Y+APEL N G S SDVYSFG+LV +++GR Sbjct: 184 GTLAYLAPELLD-NDGKASKASDVYSFGVLVWTVLAGR 220
>M3K4_HUMAN (Q9Y6R4) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1) Length = 1607 Score = 40.8 bits (94), Expect = 0.004 Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 1/108 (0%) Frame = -2 Query: 632 GTMGYIAPELYSRNFG-GVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQ 456 GT Y+APE+ +R G G +D++S G +V+EMV+G+R N +Y Sbjct: 1503 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMY------- 1555 Query: 455 KVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 KV GH + ++ E K+ + C++ +PK R + +++++ Sbjct: 1556 KVGMGHKPPIPERLSPEGKDFLSH-------CLESDPKMRWTASQLLD 1596
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 40.0 bits (92), Expect = 0.006 Identities = 36/114 (31%), Positives = 52/114 (45%), Gaps = 2/114 (1%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 + APE SR G S KSDV+SFG+L+ E+ S + P + N + + +V +G Sbjct: 353 WTAPEALSR--GHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHE-------TFLRVDAG 403 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTG--RLQNL 285 + LE + M L C +PK RP + LTG R +NL Sbjct: 404 YRMPCPLECPPNIHKLM-------LSCWSRDPKQRPCFKDLCEKLTGITRYENL 450
>M3K4_MOUSE (O08648) Mitogen-activated protein kinase kinase kinase 4 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) Length = 1597 Score = 39.3 bits (90), Expect = 0.011 Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 1/108 (0%) Frame = -2 Query: 632 GTMGYIAPELYSRNFG-GVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQ 456 GT Y+APE+ +R G G +D++S G +V+EMV+G+R N +Y Sbjct: 1493 GTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMY------- 1545 Query: 455 KVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 KV GH + ++ E K + C++ +PK R + +++++ Sbjct: 1546 KVGMGHKPPIPERLSPEGKAFLSH-------CLESDPKIRWTASQLLD 1586
>MKH1_SCHPO (Q10407) MAP kinase kinase kinase mkh1 (EC 2.7.11.25)| Length = 1116 Score = 39.3 bits (90), Expect = 0.011 Identities = 18/40 (45%), Positives = 29/40 (72%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 +G++ ++APE+ + G S K DV+S G +VLEM++GRR Sbjct: 993 QGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRR 1032
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 39.3 bits (90), Expect = 0.011 Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 11/135 (8%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T R + ++APE F KSDV+S+G+L+ E+++ + P++ + +E Sbjct: 591 TNGRLPIKWMAPESLQEKF--YDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEE------ 642 Query: 464 IYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQ-- 291 +Y ++SG E + + MRQ C +N +RP T++V + LQ Sbjct: 643 LYTYLMSGQRMEKPAKCSMNIYILMRQ-------CWHFNADDRPPFTEIVEYMDKLLQTK 695 Query: 290 ---------NLQIPP 273 NL PP Sbjct: 696 EDYLDVDIANLDTPP 710
>TMKL1_ARATH (P33543) Putative kinase-like protein TMKL1 precursor| Length = 674 Score = 38.9 bits (89), Expect = 0.014 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 5/111 (4%) Frame = -2 Query: 623 GYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVIS 444 GY APEL+ + +SDVY+FG+L+LE++ G++ + V LP + V+ Sbjct: 541 GYKAPELHKMK--KCNPRSDVYAFGILLLEILMGKKPGKSGRNGNEFVDLPSLVKAAVLE 598 Query: 443 G-----HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 D E + + +E + + + C RPSM +VV L Sbjct: 599 ETTMEVFDLEAMKGIRSPMEEGLVHALKLAMGCCAPVTTVRPSMEEVVKQL 649
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 38.9 bits (89), Expect = 0.014 Identities = 28/107 (26%), Positives = 54/107 (50%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT YIAPE+ G S++ D++S G+++ ++ G+ P + +D IY++ Sbjct: 241 GTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIGK----PPFQARD----VNTIYER 292 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 I D+ + D+ K+ I+ L +P RPS+T++++ Sbjct: 293 -IKCRDFSFPRDKPISDEGKILIRDILSL-----DPIERPSLTEIMD 333
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 38.5 bits (88), Expect = 0.019 Identities = 23/70 (32%), Positives = 37/70 (52%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE NFG + KSDV+SFG+L++E+V+ R P + N + Sbjct: 384 DNEYTAREGAKFPIKWTAPEAI--NFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE 441 Query: 485 EVYLPEWIYQ 456 + E Y+ Sbjct: 442 VIRALEHGYR 451
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 38.5 bits (88), Expect = 0.019 Identities = 23/70 (32%), Positives = 37/70 (52%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE NFG + KSDV+SFG+L++E+V+ R P + N + Sbjct: 405 DNEYTAREGAKFPIKWTAPEAI--NFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE 462 Query: 485 EVYLPEWIYQ 456 + E Y+ Sbjct: 463 VIRALEHGYR 472
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 38.5 bits (88), Expect = 0.019 Identities = 28/111 (25%), Positives = 56/111 (50%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPE 468 +T + G + Y+APE++ + S KSDVYS+GM++ E+++ S E Q ++ + Sbjct: 1462 MTQSVGCIPYMAPEVFKGDSN--SEKSDVYSYGMVLFELLT-------SDEPQQDMKPMK 1512 Query: 467 WIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVV 315 + + + L +++ KE + Q C NP +RP+ +++ Sbjct: 1513 MAHLAAYESYRPPIPLTTSSKWKEILTQ-------CWDSNPDSRPTFKQII 1556
>WNK1_HUMAN (Q9H4A3) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein) Length = 2382 Score = 38.1 bits (87), Expect = 0.025 Identities = 31/107 (28%), Positives = 53/107 (49%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ IY++ Sbjct: 385 GTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRR 434 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 V SG ++ + DK + ++ + CI+ N R S+ ++N Sbjct: 435 VTSG------VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>WNK1_MOUSE (P83741) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2377 Score = 38.1 bits (87), Expect = 0.025 Identities = 31/107 (28%), Positives = 53/107 (49%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ IY++ Sbjct: 385 GTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRR 434 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 V SG ++ + DK + ++ + CI+ N R S+ ++N Sbjct: 435 VTSG------VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 38.1 bits (87), Expect = 0.025 Identities = 21/62 (33%), Positives = 34/62 (54%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE NFG + KSDV+SFG+L++E+V+ R P + N + Sbjct: 407 DNEYTAREGAKFPIKWTAPEAI--NFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE 464 Query: 485 EV 480 + Sbjct: 465 VI 466
>IRAK3_HUMAN (Q9Y616) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 596 Score = 38.1 bits (87), Expect = 0.025 Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 3/132 (2%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR--NSDPS-VENQDE 483 + +T++ + PE Y R G +S K+DVYSFG++++E+++G R DP ++ +D Sbjct: 328 INMTSSSSKHLWYMPEEYIRQ-GKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRD- 385 Query: 482 VYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLT 303 L E + ++ + L ++ + +L + C K RPSM +V+N L Sbjct: 386 -LLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLE 444 Query: 302 GRLQNLQIPPKP 267 +L P Sbjct: 445 STQASLYFAEDP 456
>WNK1_RAT (Q9JIH7) Serine/threonine-protein kinase WNK1 (EC 2.7.11.1)| (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) Length = 2126 Score = 38.1 bits (87), Expect = 0.025 Identities = 31/107 (28%), Positives = 53/107 (49%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ IY++ Sbjct: 385 GTPEFMAPEMYEEKY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRR 434 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 V SG ++ + DK + ++ + CI+ N R S+ ++N Sbjct: 435 VTSG------VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLN 475
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 38.1 bits (87), Expect = 0.025 Identities = 33/114 (28%), Positives = 53/114 (46%), Gaps = 3/114 (2%) Frame = -2 Query: 650 TLTAARGT---MGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 T TA GT + + APE S + S KSDV++FG+L+ E+ + + P ++ Sbjct: 341 TYTAHAGTKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVY 398 Query: 479 YLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 L E Y+ +E EK+ +L C QWNP +RP+ ++ Sbjct: 399 ELLEKDYR-----------MERPEGCPEKVYELMRA---CWQWNPSDRPAFAEI 438
>CHK1_YEAST (P38147) Serine/threonine-protein kinase CHK1 (EC 2.7.11.1)| (Checkpoint kinase 1) Length = 527 Score = 37.7 bits (86), Expect = 0.032 Identities = 19/57 (33%), Positives = 37/57 (64%), Gaps = 1/57 (1%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSD-PSVENQDEVYLPE 468 RG+ Y+APE+ G + ++D++S G+L+ +++G+ + PS+EN+D V+ E Sbjct: 181 RGSPPYMAPEVLYSEEGYYADRTDIWSIGILLFVLLTGQTPWELPSLENEDFVFFIE 237
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 37.7 bits (86), Expect = 0.032 Identities = 21/62 (33%), Positives = 34/62 (54%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE NFG + KSDV+SFG+L++E+V+ R P + N + Sbjct: 385 DNEYTAREGAKFPIKWTAPEAI--NFGSSTIKSDVWSFGILLMEIVTYGRIPYPGMSNPE 442 Query: 485 EV 480 + Sbjct: 443 VI 444
>PKPA_PHYBL (Q01577) Serine/threonine-protein kinase pkpA (EC 2.7.11.1)| Length = 613 Score = 37.4 bits (85), Expect = 0.042 Identities = 17/37 (45%), Positives = 25/37 (67%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 GT ++APE+Y G + K D+Y+FGM +LEM +G Sbjct: 175 GTPEFMAPEMYEEQ--GYNEKVDIYAFGMCLLEMATG 209
>KRAF1_DROME (P11346) Raf homolog serine/threonine-protein kinase dRAF-1 (EC| 2.7.11.1) (Protein pole-hole) Length = 739 Score = 37.4 bits (85), Expect = 0.042 Identities = 29/117 (24%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQ 456 G++ ++APE+ + S++SDVY+FG+++ E+++ + N+D++ Sbjct: 587 GSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYG-HISNKDQILF------ 639 Query: 455 KVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNL 285 + G L +M+ + + L + CI++ PK+RP ++NML L+ L Sbjct: 640 --MVGRGL-LRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTL 693
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 37.4 bits (85), Expect = 0.042 Identities = 30/107 (28%), Positives = 50/107 (46%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 A+ + + APE S + S KSDV++FG+L+ E+ + + P ++ L E Y Sbjct: 285 AKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 342 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 + +E EK+ +L C QWNP +RPS ++ Sbjct: 343 R-----------MERPEGCPEKVYELMRA---CWQWNPSDRPSFAEI 375
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 37.4 bits (85), Expect = 0.042 Identities = 30/107 (28%), Positives = 50/107 (46%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 A+ + + APE S + S KSDV++FG+L+ E+ + + P ++ L E Y Sbjct: 399 AKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 456 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 + +E EK+ +L C QWNP +RPS ++ Sbjct: 457 R-----------MERPEGCPEKVYELMRA---CWQWNPSDRPSFAEI 489
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 37.4 bits (85), Expect = 0.042 Identities = 30/107 (28%), Positives = 50/107 (46%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 A+ + + APE S + S KSDV++FG+L+ E+ + + P ++ L E Y Sbjct: 399 AKFPIKWTAPE--SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 456 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 + +E EK+ +L C QWNP +RPS ++ Sbjct: 457 R-----------MERPEGCPEKVYELMRA---CWQWNPSDRPSFAEI 489
>WNK3_HUMAN (Q9BYP7) Serine/threonine-protein kinase WNK3 (EC 2.7.11.1)| (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 37.0 bits (84), Expect = 0.055 Identities = 31/107 (28%), Positives = 53/107 (49%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y ++ DVY+FGM +LEM + + P E Q+ IY+K Sbjct: 311 GTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 360 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 V SG ++ + +K ++ + CI+ N R S+ ++N Sbjct: 361 VTSG------IKPASFNKVTDPEVKEIIEGCIRQNKSERLSIRDLLN 401
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 36.6 bits (83), Expect = 0.071 Identities = 26/108 (24%), Positives = 59/108 (54%), Gaps = 1/108 (0%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT YIAPE+ + G S++ D++S G+++ ++ G+ P ++++ + IY+K Sbjct: 200 GTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGK----PPFQDKE----VKTIYRK 251 Query: 452 V-ISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 + + + + ++++AE K+ + L + +P RPS+ +V+ Sbjct: 252 IKANSYSFPSNVDISAEAKDLISSL-------LTHDPSIRPSIDDIVD 292
>KPCE_RAT (P09216) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 36.6 bits (83), Expect = 0.071 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVEN- 492 VT T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E+ Sbjct: 562 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 619 Query: 491 -QDEVYLPEWIYQKVIS 444 D+V P W+ ++ +S Sbjct: 620 LHDDVLYPVWLSKEAVS 636
>KPCE_MOUSE (P16054) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 36.6 bits (83), Expect = 0.071 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVEN- 492 VT T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E+ Sbjct: 562 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 619 Query: 491 -QDEVYLPEWIYQKVIS 444 D+V P W+ ++ +S Sbjct: 620 LHDDVLYPVWLSKEAVS 636
>KPCE_HUMAN (Q02156) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 737 Score = 36.6 bits (83), Expect = 0.071 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVEN- 492 VT T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E+ Sbjct: 562 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 619 Query: 491 -QDEVYLPEWIYQKVIS 444 D+V P W+ ++ +S Sbjct: 620 LHDDVLYPVWLSKEAVS 636
>GCN2_SCHPO (Q9HGN1) Serine/threonine-protein kinase gcn2 (EC 2.7.11.1)| Length = 1576 Score = 36.6 bits (83), Expect = 0.071 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 2/128 (1%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSY--KSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYL 474 LT GT Y+APEL SR GV Y K D+YS G+++ EM S + D + Sbjct: 817 LTTGVGTALYVAPELLSRR-NGVRYDAKVDMYSLGIILFEMCMTFSTSMERIRIIDTIRS 875 Query: 473 PEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRL 294 P ++ T + ++ +Q +P RPS ++ L Sbjct: 876 P-------------SISFPSTFPFSRASHEFKVIHC-LLQHDPTKRPSSQEL-------L 914 Query: 293 QNLQIPPK 270 ++ IPPK Sbjct: 915 ESEAIPPK 922 Score = 34.3 bits (77), Expect = 0.35 Identities = 14/34 (41%), Positives = 22/34 (64%) Frame = -2 Query: 623 GYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 G PE+ +F S K+D++ FG+LVL+M+ G Sbjct: 425 GLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCG 458
>KPCE_RABIT (P10830) Protein kinase C epsilon type (EC 2.7.11.13)| (nPKC-epsilon) Length = 736 Score = 36.6 bits (83), Expect = 0.071 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 7/77 (9%) Frame = -2 Query: 653 VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR-----RNSDPSVEN- 492 VT T GT YIAPE+ G S D ++ G+L+ EM++G+ N D E+ Sbjct: 561 VTTTTFCGTPDYIAPEILQELEYGPSV--DWWALGVLMYEMMAGQPPFEADNEDDLFESI 618 Query: 491 -QDEVYLPEWIYQKVIS 444 D+V P W+ ++ +S Sbjct: 619 LHDDVLYPVWLSKEAVS 635
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 36.2 bits (82), Expect = 0.093 Identities = 18/40 (45%), Positives = 27/40 (67%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 RGT+ ++APE+ G S K D++S G +VLEM +G+R Sbjct: 1340 RGTVFWMAPEMVDTK-QGYSAKVDIWSLGCIVLEMFAGKR 1378
>LYN_HUMAN (P07948) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 36.2 bits (82), Expect = 0.093 Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 19/82 (23%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVS-------GRRNSD 507 D A+ + + APE NFG + KSDV+SFG+L+ E+V+ GR N+D Sbjct: 393 DNEYTAREGAKFPIKWTAPEAI--NFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450 Query: 506 -----------PSVEN-QDEVY 477 P VEN DE+Y Sbjct: 451 VMTALSQGYRMPRVENCPDELY 472
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 36.2 bits (82), Expect = 0.093 Identities = 31/108 (28%), Positives = 57/108 (52%), Gaps = 1/108 (0%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSD-PSVENQDEVYLPEWIYQ 456 GT YI+PE+ +R+ G+ +SDV+S G + ++ GR D +V+N Sbjct: 173 GTPNYISPEIATRSAHGL--ESDVWSLGCMFYTLLIGRPPFDTDTVKN---------TLN 221 Query: 455 KVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 KV+ D+E+ ++ E K+ + QL ++ NP +R S++ V++ Sbjct: 222 KVVLA-DYEMPTFLSIEAKDLIHQL-------LRRNPADRLSLSSVLD 261
>STK39_RAT (O88506) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (Pancreatic serine/threonine-protein kinase) (PS/TK) (PSTK1) Length = 553 Score = 36.2 bits (82), Expect = 0.093 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 5/111 (4%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+ + G +K+D++SFG+ +E+ +G Y P + Sbjct: 243 GTPCWMAPEVMEQ-VRGYDFKADMWSFGITAIELATGAA--------PYHKYPPMKVLML 293 Query: 452 VISGHDWELTLEMTAEDKEKMRQL-----SIVGLWCIQWNPKNRPSMTKVV 315 + TLE EDKE M++ ++ L C+Q +P RP+ +++ Sbjct: 294 TLQND--PPTLETGVEDKEMMKKYGKSFRKLLSL-CLQKDPSKRPTAAELL 341
>STK39_MOUSE (Q9Z1W9) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) Length = 556 Score = 36.2 bits (82), Expect = 0.093 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 5/111 (4%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+ + G +K+D++SFG+ +E+ +G Y P + Sbjct: 246 GTPCWMAPEVMEQ-VRGYDFKADMWSFGITAIELATGAA--------PYHKYPPMKVLML 296 Query: 452 VISGHDWELTLEMTAEDKEKMRQL-----SIVGLWCIQWNPKNRPSMTKVV 315 + TLE EDKE M++ ++ L C+Q +P RP+ +++ Sbjct: 297 TLQND--PPTLETGVEDKEMMKKYGKSFRKLLSL-CLQKDPSKRPTAAELL 344
>ST32A_HUMAN (Q8WU08) Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1)| Length = 396 Score = 36.2 bits (82), Expect = 0.093 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%) Frame = -2 Query: 647 LTAARGTMGYIAPELY-SRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 +T GT Y+APE++ SR G S+ D +S G+ E++ GRR Sbjct: 177 ITTMAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRR 221
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 36.2 bits (82), Expect = 0.093 Identities = 15/43 (34%), Positives = 28/43 (65%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 +A RGT+ YI PE++ N + DVYSF +++ E+++ ++ Sbjct: 194 SALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKK 236
>STK39_HUMAN (Q9UEW8) STE20/SPS1-related proline-alanine-rich protein kinase (EC| 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT) Length = 547 Score = 36.2 bits (82), Expect = 0.093 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 5/111 (4%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+ + G +K+D++SFG+ +E+ +G Y P + Sbjct: 236 GTPCWMAPEVMEQ-VRGYDFKADMWSFGITAIELATGAA--------PYHKYPPMKVLML 286 Query: 452 VISGHDWELTLEMTAEDKEKMRQL-----SIVGLWCIQWNPKNRPSMTKVV 315 + TLE EDKE M++ ++ L C+Q +P RP+ +++ Sbjct: 287 TLQND--PPTLETGVEDKEMMKKYGKSFRKLLSL-CLQKDPSKRPTAAELL 334
>RIPK3_MOUSE (Q9QZL0) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3) Length = 486 Score = 35.8 bits (81), Expect = 0.12 Identities = 18/38 (47%), Positives = 25/38 (65%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+ Y+ PEL + S SDVYSFG+LV +++GR Sbjct: 186 GTLAYLDPELLFKVNLKASKASDVYSFGILVWAVLAGR 223
>LCK_MOUSE (P06240) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) Length = 508 Score = 35.8 bits (81), Expect = 0.12 Identities = 23/72 (31%), Positives = 37/72 (51%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R P + N + Sbjct: 390 DNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 447 Query: 485 EVYLPEWIYQKV 450 + E Y+ V Sbjct: 448 VIQNLERGYRMV 459
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 35.8 bits (81), Expect = 0.12 Identities = 23/72 (31%), Positives = 37/72 (51%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R P + N + Sbjct: 390 DNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 447 Query: 485 EVYLPEWIYQKV 450 + E Y+ V Sbjct: 448 VIQNLERGYRMV 459
>LCK_AOTNA (Q5PXS1) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.8 bits (81), Expect = 0.12 Identities = 23/72 (31%), Positives = 37/72 (51%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R P + N + Sbjct: 390 DNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE 447 Query: 485 EVYLPEWIYQKV 450 + E Y+ V Sbjct: 448 VIQNLERGYRMV 459
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 35.8 bits (81), Expect = 0.12 Identities = 24/91 (26%), Positives = 44/91 (48%) Frame = -2 Query: 578 SYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISGHDWELTLEMTAEDK 399 S KSD++SFG+L+ E+V+ P + D + +KV G+ E + + Sbjct: 665 SVKSDIWSFGILMWEIVTLGSTPYPGISAAD-------VMRKVRDGYRLE-------KPE 710 Query: 398 EKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 R+L + +C +P+ RP +++ ML Sbjct: 711 HCRRELYNIMYYCWSHDPQERPLFAEIIQML 741
>M3K6_HUMAN (O95382) Mitogen-activated protein kinase kinase kinase 6 (EC| 2.7.11.25) Length = 1011 Score = 35.8 bits (81), Expect = 0.12 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+ Y+APE+ + G +D++S G V+EM +GR Sbjct: 532 GTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGR 569
>IRAK1_MOUSE (Q62406) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK) Length = 710 Score = 35.8 bits (81), Expect = 0.12 Identities = 16/52 (30%), Positives = 34/52 (65%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 ++ ++ + RGT+ Y+ PE Y + G ++ +D +SFG+++LE ++G+R Sbjct: 373 SQSSTVARTSTVRGTLAYL-PEEYIKT-GRLAVDTDTFSFGVVILETLAGQR 422
>ST32A_MOUSE (Q8BGW6) Serine/threonine-protein kinase 32A (EC 2.7.11.1)| Length = 398 Score = 35.8 bits (81), Expect = 0.12 Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 1/45 (2%) Frame = -2 Query: 647 LTAARGTMGYIAPELY-SRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 +T GT Y+APE++ SR G S+ D +S G+ E++ GRR Sbjct: 177 ITTVAGTKPYMAPEMFTSRKETGYSFAVDWWSLGVTAYELLRGRR 221
>NEK9_XENLA (Q7ZZC8) Serine/threonine-protein kinase Nek9 (EC 2.7.11.1)| (NimA-related protein kinase 9) (XNek9) (Nercc1 kinase) Length = 944 Score = 35.8 bits (81), Expect = 0.12 Identities = 30/134 (22%), Positives = 68/134 (50%), Gaps = 4/134 (2%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSY--KSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 GT+ Y++PE+ GV Y KSD+++ G ++ E+++ R D + P + Sbjct: 195 GTLYYMSPEICQ----GVKYSFKSDIWAVGCVLYELLTLTRTFDAT--------NPLNLC 242 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN--MLTGRLQNL 285 K++ G +W + L+ T +E + + C++ +P+ RP+ +++ +L+ R +++ Sbjct: 243 VKIVQG-NWAVGLDNTVYTQELIEVVHA----CLEQDPEKRPTADEILERPILSWRRRDM 297 Query: 284 QIPPKPFVSSDNRP 243 + S+ +P Sbjct: 298 EEKVSMLNRSNKKP 311
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 35.4 bits (80), Expect = 0.16 Identities = 29/112 (25%), Positives = 52/112 (46%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 473 Query: 485 EVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPS 330 + ++V G+ + A E M Q C + +P+ RP+ Sbjct: 474 -------VLEQVERGYRMPCPQDCPASLHELMLQ-------CWKKDPEERPT 511
>LRRK1_HUMAN (Q38SD2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2038 Score = 35.4 bits (80), Expect = 0.16 Identities = 29/109 (26%), Positives = 53/109 (48%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT GY APE+ R K D++S+GM++ E++SG+R + + Q I +K Sbjct: 1449 GTPGYQAPEIRPRIV--YDEKVDMFSYGMVLYELLSGQRPALGHHQLQ--------IAKK 1498 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 + G + + ++ + R+L + + C P+ RP VV+ + Sbjct: 1499 LSKG----IRPVLGQPEEVQFRRLQALMMECWDTKPEKRPLALSVVSQM 1543
>SHK1_SCHPO (P50527) Serine/threonine-protein kinase pak1/shk1 (EC 2.7.11.1)| Length = 658 Score = 35.0 bits (79), Expect = 0.21 Identities = 20/52 (38%), Positives = 32/52 (61%), Gaps = 1/52 (1%) Frame = -2 Query: 674 CAR-DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 CA+ D ++ T GT ++APE+ +R G +K DV+S G++ +EMV G Sbjct: 527 CAQIDSNMTKRTTMVGTPYWMAPEVVTRKEYG--FKVDVWSLGIMAIEMVEG 576
>LYN_RAT (Q07014) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.0 bits (79), Expect = 0.21 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 19/82 (23%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVS-------GRRNSD 507 D A+ + + APE NFG + KSDV+SFG+L+ E+V+ GR N+D Sbjct: 393 DNEYTAREGAKFPIKWTAPEAI--NFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450 Query: 506 -----------PSVEN-QDEVY 477 P +EN DE+Y Sbjct: 451 VMTALSQGYRMPRMENCPDELY 472
>LYN_MOUSE (P25911) Tyrosine-protein kinase Lyn (EC 2.7.10.2)| Length = 511 Score = 35.0 bits (79), Expect = 0.21 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 19/82 (23%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVS-------GRRNSD 507 D A+ + + APE NFG + KSDV+SFG+L+ E+V+ GR N+D Sbjct: 393 DNEYTAREGAKFPIKWTAPEAI--NFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD 450 Query: 506 -----------PSVEN-QDEVY 477 P +EN DE+Y Sbjct: 451 VMSALSQGYRMPRMENCPDELY 472
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 35.0 bits (79), Expect = 0.21 Identities = 16/37 (43%), Positives = 27/37 (72%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 GT Y+APE+ SRN G +K+DV+S G+++ +++G Sbjct: 173 GTPAYVAPEVISRN-GYDGFKADVWSCGVILFVLLAG 208
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 35.0 bits (79), Expect = 0.21 Identities = 20/62 (32%), Positives = 33/62 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R P + N + Sbjct: 390 DNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILMTEIVTHGRIPYPGMTNPE 447 Query: 485 EV 480 + Sbjct: 448 VI 449
>IRAK3_MOUSE (Q8K4B2) Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1)| (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) Length = 609 Score = 35.0 bits (79), Expect = 0.21 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 3/137 (2%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR--NSDPS-V 498 + S + +T + PE Y R G +S K+DVYSFG++++E+++G + DP V Sbjct: 336 QQSSTINMTGGGRKHLWYMPEEYIRQ-GRLSVKTDVYSFGIVIMEVLTGCKVVLDDPKHV 394 Query: 497 ENQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 + +D L E + ++ + L ++ + +L + C+ K RP+M +V Sbjct: 395 QLRD--LLMELMEKRGLDSCLSFLDRKIPPCPRNFSAKLFSLAGRCVATKAKLRPTMDEV 452 Query: 317 VNMLTGRLQNLQIPPKP 267 ++ L +L P Sbjct: 453 LSSLESTQPSLYFAEDP 469
>ANPRB_ANGJA (P55202) Atrial natriuretic peptide receptor B precursor (ANP-B)| (ANPRB) (GC-B) (Guanylate cyclase) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor) Length = 1050 Score = 35.0 bits (79), Expect = 0.21 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 2/103 (1%) Frame = -2 Query: 620 YIAPEL--YSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVI 447 + APEL Y R+ + K DVYSFG+++ E+ RN V+ D P+ I QKV Sbjct: 690 WTAPELLIYDRHPPQGTQKGDVYSFGIILQEI--ALRNGPFYVDGMD--LSPKEIVQKVR 745 Query: 446 SGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 +G + T + +LSI+ C +P +RP + + Sbjct: 746 NGQ--KPYFRPTTDTSCHSEELSILMEGCWAEDPADRPDFSYI 786
>GUC2C_PIG (P55204) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) Length = 1073 Score = 35.0 bits (79), Expect = 0.21 Identities = 34/109 (31%), Positives = 55/109 (50%), Gaps = 4/109 (3%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQ----K 453 + APE R VS K DVYS+G++ E++ RR + ++ +D+ E I++ Sbjct: 646 WTAPEHLRR--ASVSQKGDVYSYGIIAQEIIL-RRETFYTLSCRDQ---KEKIFRVENSN 699 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 + +L LE TAE+KE L + W + +P+ RP K+ N L Sbjct: 700 GVKPFRPDLFLE-TAEEKELEVYLLVKNCW--EEDPEKRPDFKKIENTL 745
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 35.0 bits (79), Expect = 0.21 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 3/145 (2%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLE-MVSGRRNSDPSVEN 492 R +++ T + R + APE + FG S SDV+SFG+++ E M G R Sbjct: 796 RSEAVYTTMSGRSPALWAAPE--TLQFGHFSSASDVWSFGIIMWEVMAFGER-------- 845 Query: 491 QDEVYLPEWIY--QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKV 318 P W Q VI + L + +L L C Q +P RP +++ Sbjct: 846 ------PYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLM---LDCWQKDPGERPRFSQI 896 Query: 317 VNMLTGRLQNLQIPPKPFVSSDNRP 243 ++L+ +Q+ + PPK +++ RP Sbjct: 897 HSILSKMVQDPE-PPKCALTTCPRP 920
>PKNB_MYCTU (P0A5S4) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 35.0 bits (79), Expect = 0.21 Identities = 35/136 (25%), Positives = 54/136 (39%) Frame = -2 Query: 659 SIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 S+ A GT Y++PE V +SDVYS G ++ E+++G +P V Sbjct: 169 SVTQTAAVIGTAQYLSPE--QARGDSVDARSDVYSLGCVLYEVLTG----EPPFTGDSPV 222 Query: 479 YLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTG 300 V H E + +A + L V L + NP+NR + Sbjct: 223 --------SVAYQHVREDPIPPSARHEGLSADLDAVVLKALAKNPENRYQTAAEMRADLV 274 Query: 299 RLQNLQIPPKPFVSSD 252 R+ N + P P V +D Sbjct: 275 RVHNGEPPEAPKVLTD 290
>PKNB_MYCBO (P0A5S5) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 626 Score = 35.0 bits (79), Expect = 0.21 Identities = 35/136 (25%), Positives = 54/136 (39%) Frame = -2 Query: 659 SIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 S+ A GT Y++PE V +SDVYS G ++ E+++G +P V Sbjct: 169 SVTQTAAVIGTAQYLSPE--QARGDSVDARSDVYSLGCVLYEVLTG----EPPFTGDSPV 222 Query: 479 YLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTG 300 V H E + +A + L V L + NP+NR + Sbjct: 223 --------SVAYQHVREDPIPPSARHEGLSADLDAVVLKALAKNPENRYQTAAEMRADLV 274 Query: 299 RLQNLQIPPKPFVSSD 252 R+ N + P P V +D Sbjct: 275 RVHNGEPPEAPKVLTD 290
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 35.0 bits (79), Expect = 0.21 Identities = 34/129 (26%), Positives = 59/129 (45%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 ++APE S G + SD++SFG+++ E+ S + N E + + V+ G Sbjct: 1202 WMAPE--SLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSN-------EQVLKFVMDG 1252 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKPFV 261 L+ E++ L + C Q+NPK RP+ ++VN+L L + P F Sbjct: 1253 G----YLDQPDNCPERVTDLMRM---CWQFNPKMRPTFLEIVNLLKDDL-HPSFPEVSFF 1304 Query: 260 SSDNRPMPQ 234 S+ P+ Sbjct: 1305 HSEENKAPE 1313
>GRK5_RAT (Q62833) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 35.0 bits (79), Expect = 0.21 Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 12/68 (17%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG------------RRNSDPSVENQ 489 GT+GY+APE+ + G+S D + G L+ EM+ G R D V Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLET 404 Query: 488 DEVYLPEW 465 +EVY P++ Sbjct: 405 EEVYSPKF 412
>WNK4_RAT (Q7TPK6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 34.7 bits (78), Expect = 0.27 Identities = 24/64 (37%), Positives = 34/64 (53%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ IY+K Sbjct: 335 GTPEFMAPEMYEEKYDEAV---DVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 384 Query: 452 VISG 441 V SG Sbjct: 385 VTSG 388
>WNK4_MOUSE (Q80UE6) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1222 Score = 34.7 bits (78), Expect = 0.27 Identities = 24/64 (37%), Positives = 34/64 (53%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ IY+K Sbjct: 335 GTPEFMAPEMYEEKYDEAV---DVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 384 Query: 452 VISG 441 V SG Sbjct: 385 VTSG 388
>WNK4_HUMAN (Q96J92) Serine/threonine-protein kinase WNK4 (EC 2.7.11.1)| (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 34.7 bits (78), Expect = 0.27 Identities = 24/64 (37%), Positives = 34/64 (53%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y + DVY+FGM +LEM + + P E Q+ IY+K Sbjct: 338 GTPEFMAPEMYEEKYDEAV---DVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 387 Query: 452 VISG 441 V SG Sbjct: 388 VTSG 391
>M3K5_MOUSE (O35099) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1380 Score = 34.7 bits (78), Expect = 0.27 Identities = 13/38 (34%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+ Y+APE+ + G +D++S G ++EM +G+ Sbjct: 848 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 885
>M3K5_HUMAN (Q99683) Mitogen-activated protein kinase kinase kinase 5 (EC| 2.7.11.25) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis signal-regulating kinase 1) (ASK-1) Length = 1374 Score = 34.7 bits (78), Expect = 0.27 Identities = 13/38 (34%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+ Y+APE+ + G +D++S G ++EM +G+ Sbjct: 841 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGK 878
>YRK_CHICK (Q02977) Proto-oncogene tyrosine-protein kinase Yrk (EC 2.7.10.2)| (p60-Yrk) (Yes-related kinase) Length = 535 Score = 34.7 bits (78), Expect = 0.27 Identities = 20/60 (33%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + FG + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 415 DNEYTARQGAKFPIKWTAPE--AALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 472
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 34.7 bits (78), Expect = 0.27 Identities = 20/62 (32%), Positives = 33/62 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE N+G + KSDV+SFG+L+ E+V+ R P + N + Sbjct: 389 DNEYTAREGAKFPIKWTAPEAI--NYGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPE 446 Query: 485 EV 480 + Sbjct: 447 VI 448
>IRAK1_HUMAN (P51617) Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1)| (IRAK-1) Length = 712 Score = 34.7 bits (78), Expect = 0.27 Identities = 17/52 (32%), Positives = 32/52 (61%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 ++ + RGT+ Y+ PE Y + G ++ +D +SFG++VLE ++G+R Sbjct: 373 SQSSMVARTQTVRGTLAYL-PEEYIKT-GRLAVDTDTFSFGVVVLETLAGQR 422
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 34.7 bits (78), Expect = 0.27 Identities = 20/51 (39%), Positives = 31/51 (60%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 AR + + APE + N+ S KSDV+SFG+L+ E+V+ R P + N + Sbjct: 406 ARFPIKWTAPE--AANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAE 454
>PKNB_BIFLO (Q8G6P9) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 690 Score = 34.7 bits (78), Expect = 0.27 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 3/54 (5%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMG---YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 A D S T+T ++G +G Y++PE V +SD+YS G ++ EM++GR Sbjct: 170 ALDDSAATMTQSQGVVGTAQYLSPE--QARGETVDMRSDLYSAGCVLYEMLTGR 221
>FGR_FSVGR (P00544) Tyrosine-protein kinase transforming protein Fgr (EC| 2.7.10.2) Length = 545 Score = 34.7 bits (78), Expect = 0.27 Identities = 19/51 (37%), Positives = 32/51 (62%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 A+ + + APE + FG + KSDV+SFG+L+ E++S R P + N++ Sbjct: 441 AKFPIKWTAPE--AALFGRFTIKSDVWSFGILLTELISKGRVPYPGMNNRE 489
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 34.3 bits (77), Expect = 0.35 Identities = 30/106 (28%), Positives = 47/106 (44%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 + APE + N+G S +SDV+SFG+L+ E S P + NQ E Y+ Sbjct: 726 WTAPE--ALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQ 783 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLT 303 H E +S + + C + P+NRP +++ LT Sbjct: 784 HCPE--------------DISKIMMKCWDYKPENRPKFSELQKELT 815
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 34.3 bits (77), Expect = 0.35 Identities = 29/102 (28%), Positives = 49/102 (48%) Frame = -2 Query: 572 KSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEK 393 KSDV+SFG+ + E+ + + P VEN + IY + G+ L+ A+ + Sbjct: 722 KSDVWSFGVTMWEIATRGQTPYPGVENSE-------IYDYLRQGN----RLKQPADCLDG 770 Query: 392 MRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 267 + L C + NP++RPS T++ L L+ L +P Sbjct: 771 LYALM---SRCWELNPQDRPSFTELREDLENTLKALPPAQEP 809
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 34.3 bits (77), Expect = 0.35 Identities = 30/120 (25%), Positives = 52/120 (43%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 423 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNRE 480 Query: 485 EVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 + ++V G+ E MRQ C + P RP+ + + L Sbjct: 481 -------VLEQVDRGYRMPCPQGCPESLHEMMRQ-------CWKKEPDERPTFEYIQSFL 526
>PKNH_MYCBO (Q7U095) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 596 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/48 (33%), Positives = 30/48 (62%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 D+ + L A GT Y+APE +S + V+Y++D+Y+ ++ E ++G Sbjct: 166 DEKLTQLGTAVGTWKYMAPERFSND--EVTYRADIYALACVLHECLTG 211
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 34.3 bits (77), Expect = 0.35 Identities = 29/108 (26%), Positives = 57/108 (52%), Gaps = 1/108 (0%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSD-PSVENQDEVYLPEWIYQ 456 GT YI+PE+ +R+ G+ +SD++S G + ++ GR D +V+N Sbjct: 173 GTPNYISPEIATRSAHGL--ESDIWSLGCMFYTLLIGRPPFDTDTVKN---------TLN 221 Query: 455 KVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 KV+ D+E+ ++ E ++ + QL ++ NP +R S++ V++ Sbjct: 222 KVVLA-DYEMPAFLSREAQDLIHQL-------LRRNPADRLSLSSVLD 261
>PKNH_MYCTU (Q11053) Probable serine/threonine-protein kinase pknH (EC| 2.7.11.1) Length = 626 Score = 34.3 bits (77), Expect = 0.35 Identities = 16/48 (33%), Positives = 30/48 (62%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 D+ + L A GT Y+APE +S + V+Y++D+Y+ ++ E ++G Sbjct: 166 DEKLTQLGTAVGTWKYMAPERFSND--EVTYRADIYALACVLHECLTG 211
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 34.3 bits (77), Expect = 0.35 Identities = 19/50 (38%), Positives = 31/50 (62%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 AR+ T +A GT ++APE+ + S SDV+SFG+L+ E+++G Sbjct: 252 AREWHKTTKMSAAGTYAWMAPEVIRLSL--FSKSSDVWSFGVLLWELLTG 299
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 33.9 bits (76), Expect = 0.46 Identities = 14/43 (32%), Positives = 27/43 (62%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 +A RG + YI PE++ + K DVYSF +++ E+++ ++ Sbjct: 182 SALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKK 224
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 33.9 bits (76), Expect = 0.46 Identities = 30/96 (31%), Positives = 45/96 (46%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 + APE SR G S KSDV+SFG+L+ EM S + P + N + + +V +G Sbjct: 353 WTAPEALSR--GHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHE-------AFLRVDAG 403 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRP 333 + LE + M + WC +P+ RP Sbjct: 404 YRMPCPLECPPSVHKLM-----LTCWC--RDPEQRP 432
>OXSR1_PONPY (Q5R495) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 33.9 bits (76), Expect = 0.46 Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+ + G +K+D++SFG+ +E+ +G Y P + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAA--------PYHKYPPMKVLML 238 Query: 452 VISGHDWELTLEMTAEDKEKMRQL-----SIVGLWCIQWNPKNRPSMTKVV 315 + +LE +DKE +++ ++ L C+Q +P+ RP+ +++ Sbjct: 239 TLQND--PPSLETGVQDKEMLKKYGKSFRKMISL-CLQKDPEKRPTAAELL 286
>OXSR1_MOUSE (Q6P9R2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 33.9 bits (76), Expect = 0.46 Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+ + G +K+D++SFG+ +E+ +G Y P + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAA--------PYHKYPPMKVLML 238 Query: 452 VISGHDWELTLEMTAEDKEKMRQL-----SIVGLWCIQWNPKNRPSMTKVV 315 + +LE +DKE +++ ++ L C+Q +P+ RP+ +++ Sbjct: 239 TLQND--PPSLETGVQDKEMLKKYGKSFRKMISL-CLQKDPEKRPTAAELL 286
>OXSR1_HUMAN (O95747) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 527 Score = 33.9 bits (76), Expect = 0.46 Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+ + G +K+D++SFG+ +E+ +G Y P + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAA--------PYHKYPPMKVLML 238 Query: 452 VISGHDWELTLEMTAEDKEKMRQL-----SIVGLWCIQWNPKNRPSMTKVV 315 + +LE +DKE +++ ++ L C+Q +P+ RP+ +++ Sbjct: 239 TLQND--PPSLETGVQDKEMLKKYGKSFRKMISL-CLQKDPEKRPTAAELL 286
>M3K8_HUMAN (P41279) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 33.9 bits (76), Expect = 0.46 Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 1/102 (0%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQ 456 RGT Y++PE+ G S K+D+YS G ++ M +G + P V+ P ++Y Sbjct: 288 RGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY- 341 Query: 455 KVISGHDWELTLEMTAED-KEKMRQLSIVGLWCIQWNPKNRP 333 +I H LE A+D MR+L L + NP +RP Sbjct: 342 -II--HKQAPPLEDIADDCSPGMRELIEASL---ERNPNHRP 377
>LRRK1_MOUSE (Q3UHC2) Leucine-rich repeat serine/threonine-protein kinase 1 (EC| 2.7.11.1) Length = 2014 Score = 33.9 bits (76), Expect = 0.46 Identities = 28/109 (25%), Positives = 52/109 (47%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT GY APE+ R K D++S+GM++ E++SG+R + + Q I +K Sbjct: 1426 GTPGYQAPEIRPRIV--YDEKVDMFSYGMVLYELLSGQRPALGHHQLQ--------IVKK 1475 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 + G + + ++ + +L + + C P+ RP VV+ + Sbjct: 1476 LSKG----IRPVLGQPEEVQFHRLQALMMECWDTKPEKRPLALSVVSQM 1520
>KPC1B_CAEEL (P34885) Protein kinase C-like 1B (EC 2.7.11.13) (PKC1B)| Length = 707 Score = 33.9 bits (76), Expect = 0.46 Identities = 21/70 (30%), Positives = 37/70 (52%), Gaps = 7/70 (10%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN-------QDEVYL 474 GT YIAPE+ GVS D ++ G+L+ EM++G+ + E+ D+V Sbjct: 539 GTPDYIAPEILQEMEYGVSV--DWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLY 596 Query: 473 PEWIYQKVIS 444 P W+ ++ ++ Sbjct: 597 PVWLSKEAVN 606
>STE7_CANAL (P46599) Serine/threonine-protein kinase STE7 homolog (EC 2.7.12.2)| Length = 589 Score = 33.9 bits (76), Expect = 0.46 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 9/62 (14%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSY--KSDVYSFGMLVLEMVSG-------RRNSDPSVENQDEV 480 GT Y++PE G+ Y KSDV+S G++++E+ SG N+D +++D+ Sbjct: 411 GTSMYMSPE----RIQGLDYGVKSDVWSTGLMLIELASGVPVWSEDDNNNDDDEDDEDDA 466 Query: 479 YL 474 Y+ Sbjct: 467 YV 468
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 33.9 bits (76), Expect = 0.46 Identities = 19/62 (30%), Positives = 34/62 (54%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE +FG + K+DV+SFG+L++E+V+ R P + N + Sbjct: 385 DSEYTAQEGAKFPIKWTAPEAI--HFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPE 442 Query: 485 EV 480 + Sbjct: 443 VI 444
>PBS2_YEAST (P08018) MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B| resistance protein 2) (Suppressor of fluoride sensitivity 4) Length = 668 Score = 33.9 bits (76), Expect = 0.46 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 3/104 (2%) Frame = -2 Query: 632 GTMGYIAPE-LYSRNFGGVSY--KSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWI 462 G Y+APE + S N +Y +SD++S G+ +LEM GR P E D ++ Sbjct: 521 GCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPP--ETYDNIFSQ--- 575 Query: 461 YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPS 330 ++ G L + + D + L C+Q P+ RP+ Sbjct: 576 LSAIVDGPPPRLPSDKFSSDAQDFVSL------CLQKIPERRPT 613
>OXSR1_PIG (Q863I2) Serine/threonine-protein kinase OSR1 (EC 2.7.11.1)| (Oxidative stress-responsive 1 protein) Length = 529 Score = 33.9 bits (76), Expect = 0.46 Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 5/111 (4%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+ + G +K+D++SFG+ +E+ +G Y P + Sbjct: 188 GTPCWMAPEVMEQ-VRGYDFKADIWSFGITAIELATGAA--------PYHKYPPMKVLML 238 Query: 452 VISGHDWELTLEMTAEDKEKMRQL-----SIVGLWCIQWNPKNRPSMTKVV 315 + +LE +DKE +++ ++ L C+Q +P+ RP+ +++ Sbjct: 239 TLQND--PPSLETGVQDKEMLKKYGKSFRKMISL-CLQKDPEKRPTAAELL 286
>JIL1_DROME (Q9V3I5) Chromosomal serine/threonine-protein kinase JIL-1 (EC| 2.7.11.1) Length = 1207 Score = 33.9 bits (76), Expect = 0.46 Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 7/115 (6%) Frame = -2 Query: 635 RGTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 R T+ Y PE+ + N S D+Y G + M+ G R P +N+D+V Sbjct: 777 RYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHR---PYRQNEDDVD------ 827 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSI------VGLWCIQWNPKNRPSMTKVVN 312 + H+ + ++ MR S + WC+Q +P +RP+++ +++ Sbjct: 828 HSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILD 882
>SSK2_YEAST (P53599) MAP kinase kinase kinase SSK2 (EC 2.7.11.25) (Suppressor of| sensor kinase 2) Length = 1579 Score = 33.5 bits (75), Expect = 0.60 Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 2/108 (1%) Frame = -2 Query: 632 GTMGYIAPE-LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW-IY 459 GT Y+APE + G DV+S G +VLEM++GRR N D EW I Sbjct: 1459 GTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRR----PWANLDN----EWAIM 1510 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVV 315 V +GH T + +D+ + + C+ NP R S +++ Sbjct: 1511 YHVAAGH----TPQFPTKDEVSSAGMKFLER-CLIQNPSKRASAVELL 1553
>AL2S2_MOUSE (Q8K4T3) Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase) Length = 418 Score = 33.5 bits (75), Expect = 0.60 Identities = 13/34 (38%), Positives = 23/34 (67%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 +++PEL ++ G + KSD+YS G+ E+ SG+ Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>AL2S2_HUMAN (Q9C0K7) Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1)| (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP-interacting protein) (CALS-21) Length = 418 Score = 33.5 bits (75), Expect = 0.60 Identities = 13/34 (38%), Positives = 23/34 (67%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 +++PEL ++ G + KSD+YS G+ E+ SG+ Sbjct: 232 WLSPELLRQDLHGYNVKSDIYSVGITACELASGQ 265
>FYN_XENLA (P13406) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 536 Score = 33.5 bits (75), Expect = 0.60 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 473
>FYN_HUMAN (P06241) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) (Protooncogene Syn) (SLK) Length = 536 Score = 33.5 bits (75), Expect = 0.60 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 473
>KOIA_SCHPO (Q9Y7J6) Putative serine/threonine-protein kinase C1778.10c (EC| 2.7.11.1) Length = 550 Score = 33.5 bits (75), Expect = 0.60 Identities = 17/37 (45%), Positives = 24/37 (64%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 GT Y+APEL SR VS SD+++F +V +M+ G Sbjct: 222 GTAEYVAPELLSRQV--VSKSSDLWAFACVVYQMIVG 256
>GRK7_PIG (Q8WP15) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 33.5 bits (75), Expect = 0.60 Identities = 17/43 (39%), Positives = 24/43 (55%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 +T GT GY+APE+ SY D ++ G + EMV+GR Sbjct: 347 VTQRAGTNGYMAPEILMEK-ASYSYPVDWFAMGCSIYEMVAGR 388
>GRK7_HUMAN (Q8WTQ7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 553 Score = 33.5 bits (75), Expect = 0.60 Identities = 17/43 (39%), Positives = 24/43 (55%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 +T GT GY+APE+ SY D ++ G + EMV+GR Sbjct: 347 ITQRAGTNGYMAPEILMEKVS-YSYPVDWFAMGCSIYEMVAGR 388
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 33.5 bits (75), Expect = 0.60 Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 7/64 (10%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRN-SDPSVEN------QDEVYL 474 GT Y+APE+ S+ G K DV+S G+++ +V+G +DP+V N + E Sbjct: 184 GTPAYVAPEILSKK-GYEGAKVDVWSCGIVLFVLVAGYLPFNDPNVMNMYKKIYKGEYRF 242 Query: 473 PEWI 462 P W+ Sbjct: 243 PRWM 246
>TEC_MOUSE (P24604) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 630 Score = 33.5 bits (75), Expect = 0.60 Identities = 31/120 (25%), Positives = 52/120 (43%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D + + A+ + + PE++ N+ S KSDV+SFG+L+ E+ + R N + Sbjct: 515 DDQYTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYE 572 Query: 485 EVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 V + V GH K + L V L C Q P+ RPS+ ++ + Sbjct: 573 VVTM-------VTRGH-------RLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTI 618
>FYN_MOUSE (P39688) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 33.5 bits (75), Expect = 0.60 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 413 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 470
>FYN_CHICK (Q05876) Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2)| (p59-Fyn) Length = 533 Score = 33.5 bits (75), Expect = 0.60 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 413 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNRE 470
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 33.5 bits (75), Expect = 0.60 Identities = 19/50 (38%), Positives = 31/50 (62%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 AR+ T +A GT ++APE+ + S SDV+SFG+L+ E+++G Sbjct: 271 AREWHKTTQMSAAGTYAWMAPEVIKAST--FSKGSDVWSFGVLLWELLTG 318
>GRK7_SPETR (Q9Z2G7) G protein-coupled receptor kinase 7 precursor (EC| 2.7.11.16) (G protein-coupled receptor kinase GRK7) Length = 548 Score = 33.5 bits (75), Expect = 0.60 Identities = 23/77 (29%), Positives = 34/77 (44%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPE 468 +T GT GY+APE+ SY D ++ G + EMV+GR E + L E Sbjct: 342 ITQRAGTNGYMAPEILMDK-ASYSYPVDWFAMGCSIYEMVAGRTPFKDFKEKVSKEDLKE 400 Query: 467 WIYQKVISGHDWELTLE 417 + ++ H T E Sbjct: 401 RTMKDEVAFHHENFTEE 417
>WNK2_HUMAN (Q9Y3S1) Serine/threonine-protein kinase WNK2 (EC 2.7.11.1)| (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2) Length = 2297 Score = 33.5 bits (75), Expect = 0.60 Identities = 23/64 (35%), Positives = 34/64 (53%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT ++APE+Y ++ DVY+FGM +LEM + + P E Q+ IY+K Sbjct: 359 GTPEFMAPEMYEEHY---DESVDVYAFGMCMLEMAT---SEYPYSECQNAAQ----IYRK 408 Query: 452 VISG 441 V G Sbjct: 409 VTCG 412
>SRK2_SPOLA (P42688) Tyrosine-protein kinase SRK2 (EC 2.7.10.2) (Fragment)| Length = 362 Score = 33.5 bits (75), Expect = 0.60 Identities = 29/103 (28%), Positives = 47/103 (45%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 A+ + + APE + F S KSDV+SFG+L+ E+V+ R P + N + Sbjct: 250 AKFPIKWTAPE--AALFNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAE--------- 298 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPS 330 V+ D + E + Q+ L C + NP +RP+ Sbjct: 299 --VLQNLDKGYRMPCPVTTPESLYQIM---LDCWKRNPADRPT 336
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 33.1 bits (74), Expect = 0.79 Identities = 13/38 (34%), Positives = 26/38 (68%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT Y++PE+ S G + SD+++FG ++ +M++G+ Sbjct: 274 GTARYVSPEVLSDKIAGTA--SDIWAFGCILFQMLAGK 309
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 33.1 bits (74), Expect = 0.79 Identities = 33/129 (25%), Positives = 59/129 (45%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 +++PE S G + SD++SFG+++ E+ S + N E + + V+ G Sbjct: 1203 WMSPE--SLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSN-------EQVLKFVMDG 1253 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKPFV 261 L+ E++ L + C Q+NPK RP+ ++VN+L L + P F Sbjct: 1254 G----YLDPPDNCPERLTDLMRM---CWQFNPKMRPTFLEIVNLLKDDL-HPSFPEVSFF 1305 Query: 260 SSDNRPMPQ 234 S+ P+ Sbjct: 1306 YSEENKAPE 1314
>GPRK2_DROME (P32866) G protein-coupled receptor kinase 2 (EC 2.7.11.16)| Length = 714 Score = 33.1 bits (74), Expect = 0.79 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+GY+APE+ ++ D +SFG L+ EM+ G+ Sbjct: 471 GTVGYMAPEVIDNE--KYAFSPDWFSFGCLLYEMIEGQ 506
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 33.1 bits (74), Expect = 0.79 Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 13/109 (11%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVS-------GRRNSD 507 D + T + + + +PE++S F S KSDV+SFG+L+ E+ S R NS+ Sbjct: 509 DDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSE 566 Query: 506 --PSVENQDEVYLPE----WIYQKVISGHDWELTLEMTAEDKEKMRQLS 378 + +Y P +YQ I H W+ E +RQL+ Sbjct: 567 VVEDISTGFRLYKPRLASTHVYQ--IMNHCWKERPEDRPAFSRLLRQLA 613
>PKNL_MYCTU (O53510) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 33.1 bits (74), Expect = 0.79 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = -2 Query: 659 SIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 SI + GT Y++PE G +SDVYS G+LV E+++G Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTG 214
>PKNL_MYCBO (Q7TYY6) Probable serine/threonine-protein kinase pknL (EC| 2.7.11.1) Length = 399 Score = 33.1 bits (74), Expect = 0.79 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = -2 Query: 659 SIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 SI + GT Y++PE G +SDVYS G+LV E+++G Sbjct: 171 SITSTGVILGTAAYLSPEQVRD--GNADPRSDVYSVGVLVYELLTG 214
>FGR_MOUSE (P14234) Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2)| (P55-FGR) (C-FGR) Length = 517 Score = 33.1 bits (74), Expect = 0.79 Identities = 17/45 (37%), Positives = 29/45 (64%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 + APE + FG + KSDV+SFG+L+ E+++ R P + N++ Sbjct: 412 WTAPE--AALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNRE 454
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 33.1 bits (74), Expect = 0.79 Identities = 33/129 (25%), Positives = 59/129 (45%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 +++PE S G + SD++SFG+++ E+ S + N E + + V+ G Sbjct: 1192 WMSPE--SLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSN-------EQVLKFVMDG 1242 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKPFV 261 L+ E++ L + C Q+NPK RP+ ++VN+L L + P F Sbjct: 1243 G----YLDPPDNCPERLTDLMRM---CWQFNPKMRPTFLEIVNLLKDDL-HPSFPEVSFF 1294 Query: 260 SSDNRPMPQ 234 S+ P+ Sbjct: 1295 YSEENKAPE 1303
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 33.1 bits (74), Expect = 0.79 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 13/51 (25%) Frame = -2 Query: 635 RGTMGYIAPEL----YSRNFGGVSY---------KSDVYSFGMLVLEMVSG 522 RGT ++APE+ Y G +S+ KSDVYSFGM+ E+++G Sbjct: 1174 RGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTG 1224
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 32.7 bits (73), Expect = 1.0 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 420 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNRE 477
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 32.7 bits (73), Expect = 1.0 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 2/138 (1%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPE-LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 +D V AR + ++APE ++ R + + +SDV+SFG+L+ E+ S + P V+ Sbjct: 1048 KDPDYVRKGDARLPLKWMAPETIFDRVY---TIQSDVWSFGVLLWEIFSLGASPYPGVKI 1104 Query: 491 QDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 +E +++ G T E + M L C +PK RP+ +++V Sbjct: 1105 DEE------FCRRLKEGTRMRAPDYTTPEMYQTM-------LDCWHGDPKQRPTFSELVE 1151 Query: 311 MLTGRLQ-NLQIPPKPFV 261 L LQ N++ K +V Sbjct: 1152 HLGNLLQANVRQDGKDYV 1169
>ST32C_HUMAN (Q86UX6) Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE)| (YANK3) Length = 486 Score = 32.7 bits (73), Expect = 1.0 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 14/79 (17%) Frame = -2 Query: 644 TAARGTMGYIAPELYSR--NFG-GVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDE--- 483 TA GT Y+APE++ N G G S++ D +S G++ E++ G R D N E Sbjct: 248 TALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLV 307 Query: 482 --------VYLPEWIYQKV 450 Y+P W + V Sbjct: 308 QLFSTVSVQYVPTWSKEMV 326
>YES_XENLA (P10936) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 536 Score = 32.7 bits (73), Expect = 1.0 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 416 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVAKGRVPYPGMVNRE 473
>GUC2C_CAVPO (P70106) Heat-stable enterotoxin receptor precursor (GC-C)| (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (Guanylyl cyclase C) Length = 1076 Score = 32.7 bits (73), Expect = 1.0 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 2/93 (2%) Frame = -2 Query: 578 SYKSDVYSFGMLVLEMVSGRRN--SDPSVENQDEVYLPEWIYQKVISGHDWELTLEMTAE 405 S K DVYSFG++ E++ R + + +++++ E + + +L LE TAE Sbjct: 661 SQKGDVYSFGIIAQEIIMRRETFYTLSCRDQKEKIFRVE--HPDGLKPFRPDLFLE-TAE 717 Query: 404 DKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 +KE L + W + +P+ RP K+ N L Sbjct: 718 EKELEVFLLVKNCW--EEDPEKRPDFKKIENTL 748
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 32.7 bits (73), Expect = 1.0 Identities = 19/60 (31%), Positives = 33/60 (55%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+V+ R P + N++ Sbjct: 413 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNRE 470
>TXK_MOUSE (P42682) Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18)| (Resting lymphocyte kinase) Length = 527 Score = 32.7 bits (73), Expect = 1.0 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 2/123 (1%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D ++ + A+ + + PE++ +F S KSDV+SFG+L+ E+ + EN+ Sbjct: 417 DDEYISSSGAKFPVKWCPPEVF--HFNKYSSKSDVWSFGVLMWEVFT---EGKMPFENKS 471 Query: 485 EVYLPEWIYQ--KVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 + + E I Q ++ H +T+ V C +PK RP+ +++ Sbjct: 472 NLQVVEAISQGFRLYRPHLAPMTIYR-------------VMYSCWHESPKGRPTFAELLQ 518 Query: 311 MLT 303 +LT Sbjct: 519 VLT 521
>ST32C_MOUSE (Q8QZV4) Serine/threonine-protein kinase 32C (EC 2.7.11.1)| Length = 488 Score = 32.7 bits (73), Expect = 1.0 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 14/79 (17%) Frame = -2 Query: 644 TAARGTMGYIAPELYSR--NFG-GVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDE--- 483 TA GT Y+APE++ N G G S++ D +S G++ E++ G R D N E Sbjct: 249 TALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLV 308 Query: 482 --------VYLPEWIYQKV 450 Y+P W + V Sbjct: 309 QLFSTVSVQYVPTWSKEMV 327
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 32.7 bits (73), Expect = 1.0 Identities = 27/106 (25%), Positives = 48/106 (45%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 A+ + + APE S + S KSDV++FG+L+ E+ + + P ++ +Y Sbjct: 445 AKFPIKWTAPE--SLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQ-------VY 495 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTK 321 + G+ E + E MR C +W+P +RPS + Sbjct: 496 DLLEKGYRMEQPEGCPPKVYELMRA-------CWKWSPADRPSFAE 534
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 32.7 bits (73), Expect = 1.0 Identities = 27/109 (24%), Positives = 51/109 (46%) Frame = -2 Query: 569 SDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKM 390 SDV+SFG+++ E+ S + N E + + V+ G +L+ ++ Sbjct: 1206 SDVWSFGVVLWEITSLAEQPYQGLSN-------EQVLKFVMDGG----SLDHPENCPPRL 1254 Query: 389 RQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKPFVSSDNRP 243 L + C Q+NPK RP+ ++++ML L+ + S +N+P Sbjct: 1255 HSLMQM---CWQYNPKMRPTFLEIIDMLKDDLRPSFQDVSFYYSDENKP 1300
>GPRK1_DROME (P32865) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 700 Score = 32.7 bits (73), Expect = 1.0 Identities = 18/42 (42%), Positives = 28/42 (66%), Gaps = 2/42 (4%) Frame = -2 Query: 641 AARGTMGYIAPELYSRNFGGVSYKS--DVYSFGMLVLEMVSG 522 A+ GT GY+APE+ S+ G SY S D +SFG ++ +++ G Sbjct: 350 ASVGTHGYMAPEVLSK---GTSYDSCADWFSFGCMLYKLLKG 388
>TESK2_HUMAN (Q96S53) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 571 Score = 32.7 bits (73), Expect = 1.0 Identities = 32/120 (26%), Positives = 55/120 (45%) Frame = -2 Query: 641 AARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWI 462 A G+ ++APE+ + K+DV+S+G+++ E+++ R +DP YLP Sbjct: 215 AVVGSPFWMAPEVLRDE--PYNEKADVFSYGIILCEIIA-RIQADPD-------YLP--- 261 Query: 461 YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQ 282 + G D++ M + QL+ C +PK RPS ++ L L LQ Sbjct: 262 -RTENFGLDYDAFQHMVGDCPPDFLQLTFN---CCNMDPKLRPSFVEIGKTLEEILSRLQ 317
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 32.7 bits (73), Expect = 1.0 Identities = 18/50 (36%), Positives = 31/50 (62%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 AR+ T +A GT ++APE+ + S SDV+S+G+L+ E+++G Sbjct: 298 AREWHRTTKMSAAGTYAWMAPEVIRASM--FSKGSDVWSYGVLLWELLTG 345
>PKN2_COREF (Q8FUI4) Serine/threonine protein kinases drp72 (EC 2.7.11.1)| Length = 520 Score = 32.3 bits (72), Expect = 1.3 Identities = 18/39 (46%), Positives = 25/39 (64%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 GT Y++PE + V+ SDVYS G++ EM+SGRR Sbjct: 186 GTAQYVSPEQAQGH--QVTPASDVYSLGVVGYEMLSGRR 222
>UFO_MOUSE (Q00993) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (Adhesion-related kinase) Length = 888 Score = 32.3 bits (72), Expect = 1.3 Identities = 26/102 (25%), Positives = 46/102 (45%) Frame = -2 Query: 572 KSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEK 393 KSDV+SFG+ + E+ + + P VEN + IY + G+ + ++ Sbjct: 723 KSDVWSFGVTMWEIATRGQTPYPGVENSE-------IYDYLRQGNRLKQPVDFLDGLYSL 775 Query: 392 MRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKP 267 M + C + NP++RPS ++ L L+ L +P Sbjct: 776 MSR-------CWELNPRDRPSFAELREDLENTLKALPPAQEP 810
>M3K8_RAT (Q63562) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (Tumor progression locus 2) (TPL-2) Length = 467 Score = 32.3 bits (72), Expect = 1.3 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQ 456 RGT Y++PE+ G S K+D+YS G ++ M +G + P V+ P ++Y Sbjct: 288 RGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY- 341 Query: 455 KVISGHDWELTLEMTAED-KEKMRQLSIVGLWCIQWNPKNRP 333 +I H LE A D MR+L L + NP +RP Sbjct: 342 -II--HKQAPPLEDIAGDCSPGMRELIEAAL---ERNPNHRP 377
>M3K8_MOUSE (Q07174) Mitogen-activated protein kinase kinase kinase 8 (EC| 2.7.11.25) (COT proto-oncogene serine/threonine-protein kinase) (C-COT) (Cancer Osaka thyroid oncogene) Length = 467 Score = 32.3 bits (72), Expect = 1.3 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = -2 Query: 635 RGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQ 456 RGT Y++PE+ G S K+D+YS G ++ M +G + P V+ P ++Y Sbjct: 288 RGTEIYMSPEVILCR--GHSTKADIYSLGATLIHMQTG---TPPWVKRYPRSAYPSYLY- 341 Query: 455 KVISGHDWELTLEMTAED-KEKMRQLSIVGLWCIQWNPKNRP 333 +I H LE A D MR+L L + NP +RP Sbjct: 342 -II--HKQAPPLEDIAGDCSPGMRELIEAAL---ERNPNHRP 377
>TEC_HUMAN (P42680) Tyrosine-protein kinase Tec (EC 2.7.10.2)| Length = 631 Score = 32.3 bits (72), Expect = 1.3 Identities = 30/120 (25%), Positives = 51/120 (42%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D + + A+ + + PE++ N+ S KSDV+SFG+L+ E+ + R N + Sbjct: 516 DDQYTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYE 573 Query: 485 EVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 V + V GH + K + V L C Q P+ RPS ++ + Sbjct: 574 VVTM-------VTRGH-------RLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTI 619
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 32.3 bits (72), Expect = 1.3 Identities = 30/110 (27%), Positives = 53/110 (48%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 ++APE S G + SDV+SFG+++ E+V+ + N E + + V+ G Sbjct: 1158 WMAPE--SLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSN-------EQVLKFVMDG 1208 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQ 291 E E ++ QL + C Q NP+ RP+ T+++N + L+ Sbjct: 1209 GVLE-------ELEDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQKELR 1251
>ZYG1_CAEEL (Q9GT24) Probable serine/threonine-protein kinase zyg-1 (EC| 2.7.11.1) (Zygote defective protein 1) Length = 706 Score = 32.3 bits (72), Expect = 1.3 Identities = 14/38 (36%), Positives = 25/38 (65%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT G+IAP++Y + + + +DVYS G ++ M++ R Sbjct: 171 GTPGFIAPQVYDQEY---TQSADVYSLGAVLYTMLTAR 205
>RIPK4_HUMAN (P57078) Receptor-interacting serine/threonine-protein kinase 4 (EC| 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase) Length = 832 Score = 32.3 bits (72), Expect = 1.3 Identities = 29/113 (25%), Positives = 52/113 (46%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQK 453 GT+ Y+ PE K DVYSF +++ +++ ++ P + ++ ++ I K Sbjct: 183 GTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKK---PFADEKNILH----IMVK 235 Query: 452 VISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRL 294 V+ GH EL A + + ++ C Q +P+ RP+ N L G L Sbjct: 236 VVKGHRPELPPVCRARPRACSHLIRLMQR-CWQGDPRVRPTFQG--NGLNGEL 285
>KCC2_YEAST (P22517) Calcium/calmodulin-dependent protein kinase II (EC| 2.7.11.17) Length = 447 Score = 32.3 bits (72), Expect = 1.3 Identities = 24/109 (22%), Positives = 53/109 (48%) Frame = -2 Query: 638 ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIY 459 A G++GY+APE+ +++ G D++S G++ ++ G P + E ++ E Sbjct: 209 AAGSLGYVAPEVLTQD--GHGKPCDIWSIGVITYTLLCG---YSPFIAESVEGFMEE--- 260 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 + + +T M D + + L ++ NP +RP+ T++++ Sbjct: 261 ---CTASRYPVTFHMPYWDNISIDVKRFI-LKALRLNPADRPTATELLD 305
>IKKB_HUMAN (O14920) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 756 Score = 32.3 bits (72), Expect = 1.3 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 17/120 (14%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T+ GT+ Y+APEL + V+ D +SFG L E ++G R P + N V Sbjct: 180 TSFVGTLQYLAPELLEQQKYTVTV--DYWSFGTLAFECITGFR---PFLPNWQPVQWHSK 234 Query: 464 IYQK----VISGHDWELTLEMT-------------AEDKEKMRQLSIVGLWCIQWNPKNR 336 + QK ++ D T++ + AE EK QL ++ W+P+ R Sbjct: 235 VRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLM------WHPRQR 288
>GRK5_MOUSE (Q8VEB1) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+GY+APE+ + G+S D + G L+ EM+ G+ Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQ 382
>GRK5_HUMAN (P34947) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+GY+APE+ + G+S D + G L+ EM+ G+ Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQ 382
>GRK5_BOVIN (P43249) G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK5) Length = 590 Score = 32.3 bits (72), Expect = 1.3 Identities = 15/38 (39%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+GY+APE+ + G+S D + G L+ EM+ G+ Sbjct: 347 GTVGYMAPEVLNNQRYGLS--PDYWGLGCLIYEMIEGQ 382
>TYRO3_RAT (P55146) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase SKY) Length = 880 Score = 32.0 bits (71), Expect = 1.8 Identities = 27/97 (27%), Positives = 45/97 (46%) Frame = -2 Query: 569 SDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKM 390 SDV++FG+ + E+++ + +EN + IY +ISG+ + E E + M Sbjct: 703 SDVWAFGVTMWEIMTRGQTPYAGIENAE-------IYNYLISGNRLKQPPECMEEVYDLM 755 Query: 389 RQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQI 279 Q C +PK RPS T + L L +L + Sbjct: 756 YQ-------CWSADPKQRPSFTCLRMELENILGHLSV 785
>LRRK2_HUMAN (Q5S007) Leucine-rich repeat serine/threonine-protein kinase 2 (EC| 2.7.11.1) (Dardarin) Length = 2527 Score = 32.0 bits (71), Expect = 1.8 Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 9/123 (7%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSY--KSDVYSFGMLVLEM-------VSGRRNSDPSVE 495 + + GT G+ APE+ G V Y ++DVYSFG+L+ ++ V G + + E Sbjct: 2029 IKTSEGTPGFRAPEVAR---GNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPNEFDE 2085 Query: 494 NQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVV 315 + + LP+ + K W + ++ + C++ NP+ RP+ +V Sbjct: 2086 LEIQGKLPDPV--KEYGCAPWPMVEKLIKQ--------------CLKENPQERPTSAQVF 2129 Query: 314 NML 306 ++L Sbjct: 2130 DIL 2132
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 822 Score = 32.0 bits (71), Expect = 1.8 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 + APE + N+G S +SDV+SFG+L+ E S + P++ NQ Sbjct: 726 WTAPE--ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQ 767
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 32.0 bits (71), Expect = 1.8 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 + APE + N+G S +SDV+SFG+L+ E S + P++ NQ Sbjct: 513 WTAPE--ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQ 554
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 32.0 bits (71), Expect = 1.8 Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 4/40 (10%) Frame = -2 Query: 632 GTMGYIAPE-LYSRNF---GGVSYKSDVYSFGMLVLEMVS 525 GTMGY+APE L S+N GG K D++S G ++ M++ Sbjct: 331 GTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLT 370
>PKNA_MYCTU (P65726) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 32.0 bits (71), Expect = 1.8 Identities = 24/53 (45%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Frame = -2 Query: 671 ARDQSIVTLTA-ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 A D + VT T GT YIAPE + S SDVYS G++ E VSG+R Sbjct: 165 AVDAAPVTQTGMVMGTAQYIAPEQALGH--DASPASDVYSLGVVGYEAVSGKR 215
>PKNA_MYCBO (P65727) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 431 Score = 32.0 bits (71), Expect = 1.8 Identities = 24/53 (45%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Frame = -2 Query: 671 ARDQSIVTLTA-ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 A D + VT T GT YIAPE + S SDVYS G++ E VSG+R Sbjct: 165 AVDAAPVTQTGMVMGTAQYIAPEQALGH--DASPASDVYSLGVVGYEAVSGKR 215
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 32.0 bits (71), Expect = 1.8 Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Frame = -2 Query: 611 PELYSRNFGGVSYKSDVYSFGMLVLEMVSGR---RNSDPSVENQDEVY------LPEWIY 459 PEL ++N G S K DVY F ++V E+++G + D S + Y +PE+ Sbjct: 278 PEL-TKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPEYC- 335 Query: 458 QKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 D EL L +T C + +P +RP T +VN L Sbjct: 336 -------DPELKLLLTQ---------------CWEADPNDRPPFTYIVNKL 364
>SKM1_YEAST (Q12469) Serine/threonine-protein kinase SKM1 (EC 2.7.11.1)| (Protein kinase 75490 D) Length = 655 Score = 32.0 bits (71), Expect = 1.8 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 3/46 (6%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR---RNSDP 504 GT ++APE+ ++ G K DV+S G++++EM+ G N DP Sbjct: 544 GTPYWMAPEIVNQK--GYDEKVDVWSLGIMLIEMIEGEPPYLNEDP 587
>PKNA_MYCLE (P54743) Probable serine/threonine-protein kinase pknA (EC| 2.7.11.1) Length = 437 Score = 32.0 bits (71), Expect = 1.8 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Frame = -2 Query: 671 ARDQSIVTLTA-ARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 A D + VT T GT YIAPE + + SDVYS G++ E+VSG+R Sbjct: 165 AVDAAPVTQTGMVMGTAQYIAPEQALGH--DATPASDVYSLGVIGYEVVSGKR 215
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 32.0 bits (71), Expect = 1.8 Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 2/138 (1%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPE-LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 +D V AR + ++APE ++ R + + +SDV+SFG+L+ E+ S + P V+ Sbjct: 1053 KDPDYVRKGDARLPLKWMAPETIFDRVY---TIQSDVWSFGVLLWEIFSLGASPYPGVKI 1109 Query: 491 QDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 +E +++ G T E + M L C +P RPS +++V Sbjct: 1110 DEE------FCRRLKEGTRMRAPDYTTPEMYQTM-------LDCWHEDPNQRPSFSELVE 1156 Query: 311 MLTGRLQ-NLQIPPKPFV 261 L LQ N Q K ++ Sbjct: 1157 HLGNLLQANAQQDGKDYI 1174
>PKNB_MYCLE (P54744) Probable serine/threonine-protein kinase pknB (EC| 2.7.11.1) Length = 622 Score = 32.0 bits (71), Expect = 1.8 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 1/49 (2%) Frame = -2 Query: 665 DQSIVTLTAAR-GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 D + VT TAA GT Y++PE V +SDVYS G ++ E+++G Sbjct: 165 DSTSVTQTAAVIGTAQYLSPE--QARGDSVDARSDVYSLGCVLYEILTG 211
>PKNA2_BIFLO (Q8G4G1) Probable serine/threonine-protein kinase pknA2 (EC| 2.7.11.1) Length = 757 Score = 32.0 bits (71), Expect = 1.8 Identities = 14/38 (36%), Positives = 24/38 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT Y+APE+ N + + D+YS G++ EM++G+ Sbjct: 178 GTAAYLAPEMIENN--QATAQGDLYSVGIMAWEMLTGK 213
>TESK2_RAT (Q924U5) Dual specificity testis-specific protein kinase 2 (EC| 2.7.12.1) (Testicular protein kinase 2) Length = 570 Score = 32.0 bits (71), Expect = 1.8 Identities = 31/120 (25%), Positives = 55/120 (45%) Frame = -2 Query: 641 AARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWI 462 A G+ ++APE+ + K+DV+S+G+++ E+++ R +DP YLP Sbjct: 215 AVVGSPFWMAPEVLRDE--PYNEKADVFSYGIILCEIIA-RIQADPD-------YLP--- 261 Query: 461 YQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQ 282 + G D++ M + QL+ C +PK RPS ++ L + LQ Sbjct: 262 -RTENFGLDYDAFQHMVGDCPSDFLQLTFN---CCNMDPKLRPSFEEIGKTLEEIMSRLQ 317
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 32.0 bits (71), Expect = 1.8 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 + APE + N+G S +SDV+SFG+L+ E S + P++ NQ Sbjct: 381 WTAPE--ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQ 422
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 32.0 bits (71), Expect = 1.8 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 + APE + N+G S +SDV+SFG+L+ E S + P++ NQ Sbjct: 724 WTAPE--ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQ 765
>YES_MOUSE (Q04736) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 540 Score = 31.6 bits (70), Expect = 2.3 Identities = 19/60 (31%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L E+V+ R P + N++ Sbjct: 420 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNRE 477
>GRK4_RAT (P70507) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 575 Score = 31.6 bits (70), Expect = 2.3 Identities = 14/37 (37%), Positives = 23/37 (62%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 GT+GY+APE+ S ++ D + G L+ EM++G Sbjct: 347 GTVGYMAPEIISHE--KYTFSPDWWGLGCLIYEMIAG 381
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 31.6 bits (70), Expect = 2.3 Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 1/127 (0%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPE-LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 +D V +AR + ++APE ++ + + + +SDV+SFG+L+ E+ S + P V+ Sbjct: 1064 KDPDYVRKGSARLPLKWMAPESIFDKVY---TTQSDVWSFGVLLWEIFSLGASPYPGVQI 1120 Query: 491 QDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 +E Q++ G T + M L C +PK RP+ +++V Sbjct: 1121 NEE------FCQRLRDGTRMRAPELATPAIRRIM-------LNCWSGDPKARPAFSELVE 1167 Query: 311 MLTGRLQ 291 +L LQ Sbjct: 1168 ILGDLLQ 1174
>TOPK_HUMAN (Q96KB5) T-lymphokine-activated killer cell-originated protein| kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3) Length = 322 Score = 31.6 bits (70), Expect = 2.3 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 7/116 (6%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEM-------VSGRRNSDPSVENQDEVYL 474 GT + E N G ++ K+D+++FG+ + EM ++ + D + DE Sbjct: 208 GTEPWKPKEAVEEN-GVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDF 266 Query: 473 PEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNML 306 + Y + G + +E E +K+ +L V C +PK+RPS +V L Sbjct: 267 DDEAYYAAL-GTRPPINMEELDESYQKVIELFSV---CTNEDPKDRPSAAHIVEAL 318
>STE20_CANAL (Q92212) Serine/threonine-protein kinase STE20 homolog (EC 2.7.11.1)| Length = 1230 Score = 31.6 bits (70), Expect = 2.3 Identities = 16/37 (43%), Positives = 25/37 (67%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 GT ++APE+ SR G K DV+S G++++EM+ G Sbjct: 1110 GTPYWMAPEIVSRKEYGP--KVDVWSLGIMIIEMLEG 1144
>RMIL_AVEVR (P27966) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 450 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/52 (28%), Positives = 37/52 (71%), Gaps = 1/52 (1%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 G++ ++APE+ ++ S++SDVY+FG+++ E+++G+ ++ N+D++ Sbjct: 241 GSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQI 291
>GRK4_MOUSE (O70291) G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G| protein-coupled receptor kinase GRK4) Length = 574 Score = 31.6 bits (70), Expect = 2.3 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 12/64 (18%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG------------RRNSDPSVENQ 489 GT+GY+APE+ N ++ D + G L+ EM++G R + V+N+ Sbjct: 347 GTVGYMAPEII--NHEKYTFSPDWWGLGCLIYEMIAGHSPFRKYKEKVNREELERRVKNE 404 Query: 488 DEVY 477 E Y Sbjct: 405 TEEY 408
>SSK22_YEAST (P25390) Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP| kinase kinase kinase SSK22) (Suppressor of sensor kinase 22) Length = 1331 Score = 31.6 bits (70), Expect = 2.3 Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Frame = -2 Query: 650 TLTAARGTMGYIAPELYSRN-FGGVSYKSDVYSFGMLVLEMVSGRR 516 +L GT Y+APE S + G DV++ G +VLEM +GRR Sbjct: 1205 SLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRR 1250
>SRC_RSVH1 (P25020) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 31.6 bits (70), Expect = 2.3 Identities = 20/70 (28%), Positives = 36/70 (51%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 469 Query: 485 EVYLPEWIYQ 456 + E Y+ Sbjct: 470 VLDQVERAYR 479
>NEK4_MOUSE (Q9Z1J2) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) Length = 792 Score = 31.6 bits (70), Expect = 2.3 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVS 525 GT Y++PEL+S +YKSDV++ G V EM + Sbjct: 168 GTPYYMSPELFSNK--PYNYKSDVWALGCCVYEMAT 201
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 31.6 bits (70), Expect = 2.3 Identities = 17/47 (36%), Positives = 28/47 (59%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVS 525 D + T + + + +PE++S F S KSDV+SFG+L+ E+ S Sbjct: 514 DDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFGVLMWEVFS 558
>YES_HUMAN (P07947) Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2)| (p61-Yes) (c-Yes) Length = 542 Score = 31.6 bits (70), Expect = 2.3 Identities = 19/60 (31%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L E+V+ R P + N++ Sbjct: 422 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNRE 479
>GRK1_CAEEL (Q09537) G protein-coupled receptor kinase 1 (EC 2.7.11.16)| Length = 642 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/38 (39%), Positives = 22/38 (57%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT+GY+APE+ SY D + G L+ EM+ G+ Sbjct: 364 GTVGYMAPEIVKNE--RYSYGVDWWGVGCLIYEMIEGK 399
>BRAF1_HUMAN (P15056) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1) Length = 766 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/52 (28%), Positives = 37/52 (71%), Gaps = 1/52 (1%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 G++ ++APE+ ++ S++SDVY+FG+++ E+++G+ ++ N+D++ Sbjct: 615 GSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQI 665
>STLK_DROME (P83098) Putative serine/threonine-protein kinase STE20-like (EC| 2.7.11.1) Length = 346 Score = 31.6 bits (70), Expect = 2.3 Identities = 13/33 (39%), Positives = 20/33 (60%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 + APE+ +N G + K D+YS G+ EM +G Sbjct: 179 WTAPEVLYQNLSGYTEKIDIYSIGITCCEMANG 211
>PKNE_MYCTU (P72001) Serine/threonine-protein kinase pknE (EC 2.7.11.1)| Length = 566 Score = 31.6 bits (70), Expect = 2.3 Identities = 14/48 (29%), Positives = 29/48 (60%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 D+ + L GT+ Y+APE +S + +Y++D+Y+ ++ E ++G Sbjct: 166 DEKLTQLGNTVGTLYYMAPERFSESH--ATYRADIYALTCVLYECLTG 211
>PKNE_MYCBO (Q7TZN3) Serine/threonine-protein kinase pknE (EC 2.7.11.1)| Length = 566 Score = 31.6 bits (70), Expect = 2.3 Identities = 14/48 (29%), Positives = 29/48 (60%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 D+ + L GT+ Y+APE +S + +Y++D+Y+ ++ E ++G Sbjct: 166 DEKLTQLGNTVGTLYYMAPERFSESH--ATYRADIYALTCVLYECLTG 211
>BRAF1_MOUSE (P28028) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Fragment) Length = 328 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/52 (28%), Positives = 37/52 (71%), Gaps = 1/52 (1%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 G++ ++APE+ ++ S++SDVY+FG+++ E+++G+ ++ N+D++ Sbjct: 177 GSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQI 227
>RMIL_AVII1 (P10533) Serine/threonine-protein kinase transforming protein Rmil| (EC 2.7.11.1) Length = 367 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/52 (28%), Positives = 37/52 (71%), Gaps = 1/52 (1%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 G++ ++APE+ ++ S++SDVY+FG+++ E+++G+ ++ N+D++ Sbjct: 225 GSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQI 275
>IKKB_RAT (Q9QY78) Inhibitor of nuclear factor kappa B kinase beta subunit| (EC 2.7.11.1) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) Length = 757 Score = 31.6 bits (70), Expect = 2.3 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 17/120 (14%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEW 465 T+ GT+ Y+APEL + V+ D +SFG L E ++G R P + N V Sbjct: 180 TSFVGTLQYLAPELLEQQKYTVTV--DYWSFGTLAFECITGFR---PFLPNWQPVQWHSK 234 Query: 464 IYQK----VISGHDWELTLEMT-------------AEDKEKMRQLSIVGLWCIQWNPKNR 336 + QK ++ D T++ + AE EK QL + W P+ R Sbjct: 235 VRQKSEVDIVVSEDLNGTVKFSSSSPFPNNLNSVLAERLEKWLQLMLT------WQPRQR 288
>NEK4_HUMAN (P51957) Serine/threonine-protein kinase Nek4 (EC 2.7.11.1)| (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2) Length = 841 Score = 31.6 bits (70), Expect = 2.3 Identities = 16/36 (44%), Positives = 23/36 (63%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVS 525 GT Y++PEL+S +YKSDV++ G V EM + Sbjct: 168 GTPYYMSPELFSNK--PYNYKSDVWALGCCVYEMAT 201
>BRAF1_COTJA (P34908) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RMIL serine/threonine-protein kinase) (c-RMIL) Length = 807 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/52 (28%), Positives = 37/52 (71%), Gaps = 1/52 (1%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 G++ ++APE+ ++ S++SDVY+FG+++ E+++G+ ++ N+D++ Sbjct: 655 GSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQI 705
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 31.6 bits (70), Expect = 2.3 Identities = 18/44 (40%), Positives = 28/44 (63%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 + APE + N+G S +SDV+SFG+L+ E S + P++ NQ Sbjct: 724 WTAPE--ALNYGRYSSESDVWSFGILLWETFSLGASPYPNLTNQ 765
>BRAF1_CHICK (Q04982) B-Raf proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (Rmil serine/threonine-protein kinase) (c-Rmil) Length = 806 Score = 31.6 bits (70), Expect = 2.3 Identities = 15/52 (28%), Positives = 37/52 (71%), Gaps = 1/52 (1%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 G++ ++APE+ ++ S++SDVY+FG+++ E+++G+ ++ N+D++ Sbjct: 655 GSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYS-NINNRDQI 705
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 31.2 bits (69), Expect = 3.0 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 1/128 (0%) Frame = -2 Query: 671 ARDQSI-VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVE 495 +R Q + V T R + ++A E S N+ + SDV+S+G+L+ E+VS + Sbjct: 986 SRGQEVYVKKTMGRLPVRWMAIE--SLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMT 1043 Query: 494 NQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVV 315 + +Y+K+ G+ E L E + MRQ C + P RPS +++ Sbjct: 1044 CAE-------LYEKLPQGYRLEKPLNCDDEVYDLMRQ-------CWREKPYERPSFAQIL 1089 Query: 314 NMLTGRLQ 291 L L+ Sbjct: 1090 VSLNRMLE 1097
>SRC_MOUSE (P05480) Neuronal proto-oncogene tyrosine-protein kinase Src (EC| 2.7.10.2) (p60-Src) (c-Src) (pp60c-src) Length = 540 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 420 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 477
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 31.2 bits (69), Expect = 3.0 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 1/128 (0%) Frame = -2 Query: 671 ARDQSI-VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVE 495 +R Q + V T R + ++A E S N+ + SDV+S+G+L+ E+VS + Sbjct: 984 SRGQEVYVKKTMGRLPVRWMAIE--SLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMT 1041 Query: 494 NQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVV 315 + +Y+K+ G+ E L E + MRQ C + P RPS +++ Sbjct: 1042 CAE-------LYEKLPQGYRLEKPLNCDDEVYDLMRQ-------CWREKPYERPSFAQIL 1087 Query: 314 NMLTGRLQ 291 L L+ Sbjct: 1088 VSLNRMLE 1095
>SRC_AVIS2 (P15054) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 586 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 469
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 31.2 bits (69), Expect = 3.0 Identities = 32/123 (26%), Positives = 55/123 (44%) Frame = -2 Query: 647 LTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPE 468 L ++R + + APE G S KSDV+SFG+L+ E+ S R P + ++ Sbjct: 341 LDSSRLPVKWTAPEALKN--GRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKE------ 392 Query: 467 WIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQN 288 + + V G+ M D +++G C + P RP K+V L L++ Sbjct: 393 -VSEAVEKGY------RMEPPDSCPGPVHTLMGS-CWEAEPSRRPPFRKIVEKLGRELRS 444 Query: 287 LQI 279 + + Sbjct: 445 VGV 447
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 31.2 bits (69), Expect = 3.0 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 1/127 (0%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPE-LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 +D V +AR + ++APE ++ + + + +SDV+SFG+L+ E+ S + P V+ Sbjct: 1064 KDPDYVRKGSARLPLKWMAPESIFDKVY---TTQSDVWSFGVLLWEIFSLGASPYPGVQI 1120 Query: 491 QDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 +E Q++ G T + M+ C +PK RP+ + +V Sbjct: 1121 NEE------FCQRLKDGTRMRAPELATPAIRHIMQS-------CWSGDPKARPAFSDLVE 1167 Query: 311 MLTGRLQ 291 +L LQ Sbjct: 1168 ILGDLLQ 1174
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 31.2 bits (69), Expect = 3.0 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 1/127 (0%) Frame = -2 Query: 668 RDQSIVTLTAARGTMGYIAPE-LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 +D V +AR + ++APE ++ + + + +SDV+SFG+L+ E+ S + P V+ Sbjct: 1064 KDPDYVRKGSARLPLKWMAPESIFDKVY---TTQSDVWSFGVLLWEIFSLGASPYPGVQI 1120 Query: 491 QDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVN 312 +E Q++ G T + M+ C +PK RP+ + +V Sbjct: 1121 NEE------FCQRLKDGTRMRAPELATPAIRHIMQS-------CWSGDPKARPAFSDLVE 1167 Query: 311 MLTGRLQ 291 +L LQ Sbjct: 1168 ILGDLLQ 1174
>SRC_AVIST (P14085) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 556 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 469
>PKSC_STRCO (Q9S2C0) Serine/threonine protein kinase pksC (EC 2.7.11.1)| Length = 556 Score = 31.2 bits (69), Expect = 3.0 Identities = 15/38 (39%), Positives = 25/38 (65%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT Y++PE GV +SD+YS G+++ ++V+GR Sbjct: 191 GTPQYLSPEQALGR--GVDARSDLYSVGIMLFQLVTGR 226
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 31.2 bits (69), Expect = 3.0 Identities = 32/126 (25%), Positives = 54/126 (42%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 +++PE S G + SDV+SFG+++ E+ + + N E + + V+ G Sbjct: 1174 WMSPE--SLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSN-------EQVLRFVMEG 1224 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLTGRLQNLQIPPKPFV 261 E E MR C Q+NPK RPS ++++ + L F Sbjct: 1225 GLLEKPDNCPDMLFELMRM-------CWQFNPKMRPSFLEIISSIKDELDPGFKEVSFFY 1277 Query: 260 SSDNRP 243 S +N+P Sbjct: 1278 SEENKP 1283
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 31.2 bits (69), Expect = 3.0 Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 1/128 (0%) Frame = -2 Query: 671 ARDQSI-VTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVE 495 +R Q + V T R + ++A E S N+ + SDV+S+G+L+ E+VS + Sbjct: 987 SRGQEVYVKKTMGRLPVRWMAIE--SLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMT 1044 Query: 494 NQDEVYLPEWIYQKVISGHDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVV 315 + +Y+K+ G+ E L E + MRQ C + P RPS +++ Sbjct: 1045 CAE-------LYEKLPQGYRLEKPLNCDDEVYDLMRQ-------CWREKPYERPSFAQIL 1090 Query: 314 NMLTGRLQ 291 L L+ Sbjct: 1091 VSLNRMLE 1098
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 31.2 bits (69), Expect = 3.0 Identities = 19/58 (32%), Positives = 30/58 (51%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVEN 492 D AR + + APE + +G + KSDV+SFG+L+ E+ + R P + N Sbjct: 409 DNEYTARPGARFPVKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN 464
>SRC_RSVP (P00526) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 469
>SRC_CHICK (P00523) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 532 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 469
>SRC_AVISS (P14084) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 567 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 412 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 469
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 31.2 bits (69), Expect = 3.0 Identities = 16/50 (32%), Positives = 30/50 (60%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSG 522 AR+ T + GT ++APE+ + S SD++S+G+L+ E+++G Sbjct: 293 AREWHRTTKMSTAGTYAWMAPEVIKSSL--FSKGSDIWSYGVLLWELLTG 340
>SRC_RAT (Q9WUD9) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 415 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 472
>SRC_HUMAN (P12931) Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2)| (p60-Src) (c-Src) (pp60c-src) Length = 535 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 415 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 472
>SRC2_XENLA (P13116) Tyrosine-protein kinase Src-2 (EC 2.7.10.2) (p60-Src-2)| Length = 531 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 411 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 468
>SRC1_XENLA (P13115) Tyrosine-protein kinase Src-1 (EC 2.7.10.2) (p60-Src-1)| Length = 531 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/60 (30%), Positives = 32/60 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE + +G + KSDV+SFG+L+ E+ + R P + N++ Sbjct: 411 DNEYTARQGAKFPIKWTAPE--AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE 468
>PKN2_CLOAB (Q97IC2) Probable serine/threonine protein kinase CAC1728 (EC| 2.7.11.1) Length = 657 Score = 31.2 bits (69), Expect = 3.0 Identities = 15/51 (29%), Positives = 29/51 (56%) Frame = -2 Query: 671 ARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 + + +I T G+ Y++PE V ++D+YSFG+++ EM +G+ Sbjct: 158 SNESTITTTNKVVGSAHYLSPE--QAQGIPVDCRTDIYSFGIVLYEMATGK 206
>MEK2_CAEEL (Q10664) Dual specificity mitogen-activated protein kinase kinase| mek-2 (EC 2.7.12.2) (MAP kinase kinase mek-2) Length = 387 Score = 31.2 bits (69), Expect = 3.0 Identities = 15/38 (39%), Positives = 26/38 (68%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT Y+APE + + +S SD++SFG+ ++E++ GR Sbjct: 230 GTRSYMAPERLTGSHYTIS--SDIWSFGLSLVELLIGR 265
>IKKA_MOUSE (Q60680) Inhibitor of nuclear factor kappa-B kinase alpha subunit| (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor N Length = 745 Score = 31.2 bits (69), Expect = 3.0 Identities = 16/43 (37%), Positives = 25/43 (58%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 T+ GT+ Y+APEL+ + D +SFG +V E ++G R Sbjct: 179 TSFVGTLQYLAPELFENK--PYTATVDYWSFGTMVFECIAGYR 219
>IKKA_HUMAN (O15111) Inhibitor of nuclear factor kappa-B kinase alpha subunit| (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop-helix ubiquitous kinase) (Nuclear factor N Length = 745 Score = 31.2 bits (69), Expect = 3.0 Identities = 16/43 (37%), Positives = 25/43 (58%) Frame = -2 Query: 644 TAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRR 516 T+ GT+ Y+APEL+ + D +SFG +V E ++G R Sbjct: 179 TSFVGTLQYLAPELFENK--PYTATVDYWSFGTMVFECIAGYR 219
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 31.2 bits (69), Expect = 3.0 Identities = 15/38 (39%), Positives = 25/38 (65%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT YIAPE+ S+ G S++ DV+S G ++ ++ G+ Sbjct: 213 GTPNYIAPEVLSKK--GHSFEVDVWSIGCIMYTLLVGK 248
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 31.2 bits (69), Expect = 3.0 Identities = 15/38 (39%), Positives = 25/38 (65%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT YIAPE+ S+ G S++ DV+S G ++ ++ G+ Sbjct: 213 GTPNYIAPEVLSKK--GHSFEVDVWSIGCIMYTLLVGK 248
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 31.2 bits (69), Expect = 3.0 Identities = 15/38 (39%), Positives = 25/38 (65%) Frame = -2 Query: 632 GTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGR 519 GT YIAPE+ S+ G S++ DV+S G ++ ++ G+ Sbjct: 213 GTPNYIAPEVLSKK--GHSFEVDVWSIGCIMYTLLVGK 248
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 31.2 bits (69), Expect = 3.0 Identities = 18/62 (29%), Positives = 33/62 (53%) Frame = -2 Query: 665 DQSIVTLTAARGTMGYIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQD 486 D A+ + + APE +FG + K+DV+SFG+L++ +V+ R P + N + Sbjct: 379 DSEYTAQEGAKFPIKWTAPEAI--HFGVFTIKADVWSFGVLLMVIVTYGRVPYPGMSNPE 436 Query: 485 EV 480 + Sbjct: 437 VI 438
>Y103_ENCCU (Q8STG1) Hypothetical protein| ECU01_0030/ECU01_1580/ECU04_0040/ECU05_0010/ ECU08_2140/ECU10_1890 Length = 123 Score = 31.2 bits (69), Expect = 3.0 Identities = 29/98 (29%), Positives = 40/98 (40%), Gaps = 13/98 (13%) Frame = -3 Query: 598 LGTLEGCLTSQMCTVLECWCWKW*ADGGTQIQVLRTRTRCISLSGST----RK*SVGMIG 431 + T GC+ +MC W+ DGGT+ Q + R R + L R +G +G Sbjct: 33 MATRLGCIQREMCEGAVSGLWEEGEDGGTRTQ-MGKRAREVGLEEGVLLLWRTLDLGGVG 91 Query: 430 ---------SLLWK*QQRTRRR*DS*VLWGCGASSGTR 344 SL +QR+ R WGCG SS R Sbjct: 92 GRKLGSEGQSLSENSEQRSLMR------WGCGGSSERR 123
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 30.8 bits (68), Expect = 3.9 Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 2/46 (4%) Frame = -2 Query: 620 YIAPE--LYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQ 489 + APE LY+R + KSDV+SFG+L+ E+V+ R P + N+ Sbjct: 228 WTAPEAALYNR----FTIKSDVWSFGVLISEIVTHGRMPYPGMTNR 269
>RAF1_CHICK (P05625) RAF proto-oncogene serine/threonine-protein kinase (EC| 2.7.11.1) (RAF-1) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (C-MIL) Length = 647 Score = 30.8 bits (68), Expect = 3.9 Identities = 15/52 (28%), Positives = 35/52 (67%), Gaps = 1/52 (1%) Frame = -2 Query: 632 GTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEV 480 G++ ++APE+ ++ S++SDVYS+G+++ E+++G + N+D++ Sbjct: 507 GSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYS-HINNRDQI 557
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 30.8 bits (68), Expect = 3.9 Identities = 29/106 (27%), Positives = 50/106 (47%) Frame = -2 Query: 620 YIAPELYSRNFGGVSYKSDVYSFGMLVLEMVSGRRNSDPSVENQDEVYLPEWIYQKVISG 441 + APE + N+G S +SDV+SFG+L+ E S P + NQ ++V G Sbjct: 227 WTAPE--ALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQ-------AREQVERG 277 Query: 440 HDWELTLEMTAEDKEKMRQLSIVGLWCIQWNPKNRPSMTKVVNMLT 303 + M+A + ++ + + C + P+NRP + + LT Sbjct: 278 Y------RMSA-PQNCPEEIFTIMMKCWDYKPENRPKFSDLHKELT 316
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 30.8 bits (68), Expect = 3.9 Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Frame = -2 Query: 650 TLTAARGTMGYIAPELYS-RNFGGVSYKSDVYSFGMLVLEMVSG 522 TL GT Y+APEL R + G +K D++S G+++ +++G Sbjct: 187 TLETVCGTTVYMAPELIERRTYDG--FKIDIWSLGVILYTLITG 228 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 104,005,104 Number of Sequences: 219361 Number of extensions: 2404124 Number of successful extensions: 7182 Number of sequences better than 10.0: 330 Number of HSP's better than 10.0 without gapping: 6769 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7102 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6598423128 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
