>LEU2_BUCUA (Q9EVG5) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)|
           (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI)
           (Fragment)
          Length = 443

 Score = 37.4 bits (85), Expect = 0.046
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
 Frame = +1

Query: 340 NMEEKILTYKRLSQVIKYHEAKSSS--ILLQSKTYLTNSSLSRIGSSLYTSANSGDL 504
           +++EKI  Y  ++ ++K   AKS+   + LQS TYLTN S+ ++     T+A   DL
Sbjct: 299 SIDEKIPDYNNINSIVKRKSAKSACEYMGLQSNTYLTNISIDKVFIGSCTNARIEDL 355

>LEU2_BUCUS (Q9EVI3) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)|
           (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI)
           (Fragment)
          Length = 442

 Score = 37.4 bits (85), Expect = 0.046
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 6/69 (8%)
 Frame = +1

Query: 340 NMEEKILTYKRLSQVIKYHEAKSSS--ILLQSKTYLTNSSLSRIGSSLYTSANSGDL--- 504
           +++EKI  Y  ++  IK   +KS+   + LQS TYLTN S+ R+     T+A   DL   
Sbjct: 299 SIDEKIPDYNNINSAIKRESSKSACEYMGLQSNTYLTNISIDRVFIGSCTNARIEDLRSA 358

Query: 505 -DMLKSFKI 528
             +LK+ KI
Sbjct: 359 SKILKNKKI 367

>LEU2_BUCUM (Q9EVG8) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)|
           (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI)
           (Fragment)
          Length = 444

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 6/69 (8%)
 Frame = +1

Query: 340 NMEEKILTYKRLSQVIKYHEAKSSS--ILLQSKTYLTNSSLSRIGSSLYTSANSGDL--- 504
           +++EKI  Y  ++ ++K   AKS+   + L+S TYLTN S+ R+     T+A   DL   
Sbjct: 300 SIDEKIPDYNNINSLLKKESAKSACEYMGLKSNTYLTNISIDRVFIGSCTNARIEDLRAA 359

Query: 505 -DMLKSFKI 528
             +LK+ KI
Sbjct: 360 SKILKNRKI 368

>LEU2_BUCUO (Q9EVI0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)|
           (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI)
           (Fragment)
          Length = 443

 Score = 35.0 bits (79), Expect = 0.23
 Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
 Frame = +1

Query: 340 NMEEKILTYKRLSQVIKYHEAKSSS--ILLQSKTYLTNSSLSRIGSSLYTSANSGDL 504
           ++ EKI  Y ++  ++K   AKS+   + L+S TYLTN S+ R+     T+A   DL
Sbjct: 299 SINEKIPDYNKIDSLVKKDAAKSACKYMGLRSDTYLTNISIDRVFIGSCTNARIEDL 355

>LEU2_BUCUD (Q9EVE0) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)|
           (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI)
           (Fragment)
          Length = 444

 Score = 34.3 bits (77), Expect = 0.39
 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
 Frame = +1

Query: 340 NMEEKILTYKRLSQVIKYHEAKSSS--ILLQSKTYLTNSSLSRIGSSLYTSANSGDL 504
           +++EKI  Y  ++  +K   AKS+   + L+S TYLTN S+ ++     T+A   DL
Sbjct: 300 SIDEKIPDYNNINSEVKKDSAKSACKYMGLKSNTYLTNISIDKVFIGSXTNARIEDL 356

>LEU2_BUCUN (Q9EVI6) 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)|
           (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI)
           (Fragment)
          Length = 443

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 6/69 (8%)
 Frame = +1

Query: 340 NMEEKILTYKRLSQVIKYHEAKSSS--ILLQSKTYLTNSSLSRIGSSLYTSANSGDL--- 504
           +++EKI  +  ++  IK   AKS+   + L+S TYLTN S+ ++     T+A   DL   
Sbjct: 299 SIDEKIPDFNDVNSTIKKDSAKSACEYMGLKSNTYLTNISIDKVFIGSCTNARIEDLRSA 358

Query: 505 -DMLKSFKI 528
             +LK+ KI
Sbjct: 359 AGILKNKKI 367

>PDE4D_DROME (Q9W4T0) cAMP-specific 3',5'-cyclic phosphodiesterase, isoform M|
           (EC 3.1.4.17) (Learning/memory process protein) (Protein
           dunce)
          Length = 903

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
 Frame = -3

Query: 545 AGCI-----PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           A CI     P +   F ++ S E AL+Y DE +L+N  L
Sbjct: 601 AACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHL 639

>PDE4A_DROME (Q9W4T4) cAMP-specific 3',5'-cyclic phosphodiesterase, isoform I (EC|
            3.1.4.17) (Learning/memory process protein) (Protein
            dunce)
          Length = 1209

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
 Frame = -3

Query: 545  AGCI-----PSILKDFNISKSPEFALVYRDEPILDNEEL 444
            A CI     P +   F ++ S E AL+Y DE +L+N  L
Sbjct: 907  AACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHL 945

>PDE4E_DROME (Q8IRU4) cAMP-specific 3',5'-cyclic phosphodiesterase, isoform F|
           (EC 3.1.4.17) (Learning/memory process protein) (Protein
           dunce)
          Length = 662

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
 Frame = -3

Query: 545 AGCI-----PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           A CI     P +   F ++ S E AL+Y DE +L+N  L
Sbjct: 360 AACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHL 398

>PDE4C_DROME (Q9W4S9) cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G|
           (EC 3.1.4.17) (Learning/memory process protein) (Protein
           dunce)
          Length = 983

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
 Frame = -3

Query: 545 AGCI-----PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           A CI     P +   F ++ S E AL+Y DE +L+N  L
Sbjct: 681 AACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHL 719

>PDE4B_DROME (P12252) cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms|
           II/III/IV/V/VI/VII (EC 3.1.4.17) (Learning/memory
           process protein) (Protein dunce)
          Length = 1070

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
 Frame = -3

Query: 545 AGCI-----PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           A CI     P +   F ++ S E AL+Y DE +L+N  L
Sbjct: 768 AACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHL 806

>UPPS_BACCR (Q819Y1) Undecaprenyl pyrophosphate synthetase (EC 2.5.1.31) (UPP|
           synthetase) (Di-trans,poly-cis-decaprenylcistransferase)
           (Undecaprenyl diphosphate synthase) (UDS)
          Length = 258

 Score = 30.4 bits (67), Expect = 5.6
 Identities = 12/32 (37%), Positives = 21/32 (65%)
 Frame = +3

Query: 69  NFAIXEQIYDEYYTSNIFINSAKEKHLLNGIT 164
           NF + +  Y E++ ++++    KE+HLLN IT
Sbjct: 215 NFMLWQIAYSEFWFTDVYWPDFKEEHLLNAIT 246

>PDE4A_RAT (P54748) cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC|
           3.1.4.17) (DPDE2)
          Length = 844

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = -3

Query: 533 PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           P +   F I+ + E AL+Y DE +L+N  L
Sbjct: 464 PGVSNQFLINTNSELALMYNDESVLENHHL 493

>PDE4A_MOUSE (O89084) cAMP-dependent 3',5'-cyclic phosphodiesterase 4A (EC|
           3.1.4.17)
          Length = 844

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = -3

Query: 533 PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           P +   F I+ + E AL+Y DE +L+N  L
Sbjct: 464 PGVSNQFLINTNSELALMYNDESVLENHHL 493

>PDE4A_HUMAN (P27815) cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC|
           3.1.4.17) (DPDE2) (PDE46)
          Length = 886

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = -3

Query: 533 PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           P +   F I+ + E AL+Y DE +L+N  L
Sbjct: 478 PGVSNQFLINTNSELALMYNDESVLENHHL 507

>PDE4B_HUMAN (Q07343) cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC|
           3.1.4.17) (DPDE4) (PDE32)
          Length = 736

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = -3

Query: 533 PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           P +   F I+ + E AL+Y DE +L+N  L
Sbjct: 451 PGVSNQFLINTNSELALMYNDESVLENHHL 480

>PDE4B_RAT (P14646) cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC|
           3.1.4.17) (DPDE4)
          Length = 721

 Score = 29.6 bits (65), Expect = 9.6
 Identities = 12/30 (40%), Positives = 18/30 (60%)
 Frame = -3

Query: 533 PSILKDFNISKSPEFALVYRDEPILDNEEL 444
           P +   F I+ + E AL+Y DE +L+N  L
Sbjct: 436 PGVSNQFLINTNSELALMYNDESVLENHHL 465


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,486,271
Number of Sequences: 219361
Number of extensions: 1594583
Number of successful extensions: 3040
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 2996
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3038
length of database: 80,573,946
effective HSP length: 109
effective length of database: 56,663,597
effective search space used: 7252940416
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)