ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbaal10n02 |
|---|---|
| Clone Library Name | barley_pub |
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 173 bits (439), Expect = 4e-43 Identities = 79/172 (45%), Positives = 116/172 (67%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 PEWQER R+EVL+ FG P+ LN LK ++M+L+E LRLY P + + + D +GS Sbjct: 352 PEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIVHKDTKLGS 411 Query: 467 LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCI 288 +P G +++P ++HR+K +WG+DA EF P+RF +G+ A K L FS GPR C+ Sbjct: 412 YTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVANATKNNVTYLPFSWGPRVCL 471 Query: 287 GQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPLD 132 GQNF++L+AK LA++LQ+F F ++P YVHAP I T++P+FG V + L+ Sbjct: 472 GQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKLE 523
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 97.1 bits (240), Expect = 5e-20 Identities = 66/178 (37%), Positives = 92/178 (51%), Gaps = 2/178 (1%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A PE Q+ R+EV G Q S + L K+ +TM + E RLY P + R+ Sbjct: 329 CMALYPEHQQLCREEVRGILGDQDSFQWDDLAKMTYLTMCMKECFRLYPPVPQVYRQLNK 388 Query: 485 DMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 +T V LP G I + I +HR+ VW D + F PLRF A + P + FS Sbjct: 389 PVTFVDGRSLPAGSLISLHIYALHRNSTVW-PDPEVFDPLRFSPE-NAAGRHPFAFMPFS 446 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 GPR+CIGQ F+M E K AL L +F F+L P + V L+ K G+ ++++PL Sbjct: 447 AGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQLILRSKNGIHLYLKPL 504
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 97.1 bits (240), Expect = 5e-20 Identities = 63/178 (35%), Positives = 95/178 (53%), Gaps = 2/178 (1%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A PE Q+R R+EV + G Q S L K+ +TM + E RLY P + R+ Sbjct: 325 CMALYPEHQQRCREEVREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSK 384 Query: 485 DMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 ++ V LP G I + I +HR+ +VW D + F PLRF + + P+ + FS Sbjct: 385 PVSFVDGRSLPAGSLISLHIYALHRNSDVW-PDPEVFDPLRFSPE-NSSGRHPYAFIPFS 442 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 GPR+CIGQ F+M E K AL L +F F++ P + + L+ K G+ ++++PL Sbjct: 443 AGPRNCIGQQFAMNEMKVVTALCLLRFEFSVDPLRLPIKLPQLVLRSKNGIHLYLKPL 500
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 95.1 bits (235), Expect = 2e-19 Identities = 50/143 (34%), Positives = 86/143 (60%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ F ++P +AL +++ + MV+ ETLRLY A ++R D+ + Sbjct: 325 PDVQQKLQEEIEATFPNKAPPTYDALAQMEYLDMVVNETLRLYPIAARLERACKKDVEIH 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG +V+P+ ++HRD ++W + +EF+P RF P+ L F GPR+C Sbjct: 385 GVFVPKGTVVVVPVFVLHRDPDLW-PEPEEFRPERFSKKHKDTIN-PYTYLPFGTGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F+++ K L +LQ FSF Sbjct: 443 IGMRFALMNMKLALVRVLQNFSF 465
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 93.6 bits (231), Expect = 5e-19 Identities = 64/179 (35%), Positives = 93/179 (51%), Gaps = 3/179 (1%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFG-MQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A P Q+R R+EV + G S + L ++ +TM + E RLY P + R+ Sbjct: 330 CMALYPMHQQRCREEVREILGDRDSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSK 389 Query: 485 DMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK-NGITGAAKVPHGLLAF 312 +T V LP G I + I +HR+ VW D + F PLRF +TG + P + F Sbjct: 390 PVTFVDGRSLPAGSLISLHIYALHRNSAVW-PDPEVFDPLRFSPENMTG--RHPFAFMPF 446 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 S GPR+CIGQ F+M E K AL L +F F+ P + V L+ K G+ ++++PL Sbjct: 447 SAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVPQLILRSKNGIHLYLKPL 505
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 92.8 bits (229), Expect = 9e-19 Identities = 62/178 (34%), Positives = 90/178 (50%), Gaps = 2/178 (1%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A PE Q R R+EV + G Q + L K+ +TM + E+ RLY P + R+ Sbjct: 330 CMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSK 389 Query: 485 DMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 +T V LP G I + I +HR+ VW D + F LRF + + P + FS Sbjct: 390 PVTFVDGRSLPAGSLISMHIYALHRNSAVW-PDPEVFDSLRFSTE-NASKRHPFAFMPFS 447 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 GPR+CIGQ F+M E K A+ L +F F+L P + + L+ K G + ++PL Sbjct: 448 AGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPL 505
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 92.0 bits (227), Expect = 1e-18 Identities = 57/173 (32%), Positives = 91/173 (52%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 P+ Q+R +E + G + + + V+ ETLR+Y F RK + D+ VG Sbjct: 327 PDVQQRAFEEASELEGREK------ESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGK 380 Query: 467 LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCI 288 L +PKG +I I ++HRD + + D + F P RF + P AFS GPR+CI Sbjct: 381 LTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL--VNEKQMHPFAFAAFSAGPRNCI 437 Query: 287 GQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPLDK 129 GQ F+MLE K++LA++L+ + F D+ P+ K G+++ + P D+ Sbjct: 438 GQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSGNGIRLRILPRDE 490
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 91.3 bits (225), Expect = 3e-18 Identities = 47/143 (32%), Positives = 86/143 (60%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ F ++P + L +++ + MV+ ETLR++ A+ + R D+ + Sbjct: 325 PDVQQKLQEEIDATFPNKAPPTYDVLAQMEYLDMVVNETLRMFPIAVRLDRLCKKDVEIH 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG A+ +PI ++HRD ++W + +EF+P RF + P+ L F GPR+C Sbjct: 385 GVSIPKGTAVTVPIFVLHRDPQLW-PEPEEFRPERFSKKNKDSIN-PYVYLPFGTGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F+++ K + +LQ FSF Sbjct: 443 IGMRFAIMNMKLAIVRVLQNFSF 465
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 90.9 bits (224), Expect = 3e-18 Identities = 56/146 (38%), Positives = 79/146 (54%), Gaps = 4/146 (2%) Frame = -1 Query: 590 PDPNALNKLKEMTMVLFETLRLYSPA----LFMQRKTVADMTVGSLKLPKGIAIVIPIPI 423 P + +LK + MVL E LRL+ A L+ + TV G L KG +++ IP Sbjct: 303 PSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLG---GEYPLEKGDELMVLIPQ 359 Query: 422 MHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLAL 243 +HRDK +WGDD +EF+P RF+N +A H F G R+CIGQ F++ EA L + Sbjct: 360 LHRDKTIWGDDVEEFRPERFEN---PSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGM 416 Query: 242 MLQKFSFTLSPDYVHAPVDIFTLKPK 165 ML+ F F +Y + TLKP+ Sbjct: 417 MLKHFDFEDHTNYELDIKETLTLKPE 442
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 90.9 bits (224), Expect = 3e-18 Identities = 50/143 (34%), Positives = 79/143 (55%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQ-RKTVADMTVG 471 PE Q++L++EV +E + L+KLK M V E LRLY F R+ + + +G Sbjct: 346 PEIQKKLQEEVNRECPNPEVTIDQLSKLKYMECVFKEALRLYPLGAFANSRRCMRNTKLG 405 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 ++K+ G I + +H D +WGDDA++FKP R++ + G + F +GPR C Sbjct: 406 NMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQKSGYIPFGLGPRQC 465 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG + +E K L +L+KF+F Sbjct: 466 IGMRLAYMEEKILLVHILRKFTF 488
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 90.1 bits (222), Expect = 6e-18 Identities = 58/154 (37%), Positives = 85/154 (55%), Gaps = 5/154 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFETLRLYSPA-LFMQRKTVAD 483 PE Q++L++EV +E PDP L+KLK + V+ E LRLY A L RK + Sbjct: 346 PEIQKKLQEEVDRE----CPDPEVTFDQLSKLKYLECVVKEALRLYPLASLVHNRKCLKT 401 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 V +++ G I + +H D +VWGDD +EFKP R+++G G L F MG Sbjct: 402 TNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWESG-DELFFAKGGYLPFGMG 460 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYV 201 PR CIG +M+E K L +L+ ++F +P+ V Sbjct: 461 PRICIGMRLAMMEMKMLLTNILKNYTFETTPETV 494
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 90.1 bits (222), Expect = 6e-18 Identities = 50/143 (34%), Positives = 85/143 (59%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ F ++ P +AL +++ + MVL ETLRLY A ++R D+ + Sbjct: 325 PDVQQKLQEEIDATFPNKALPTYDALVQMEYLDMVLNETLRLYPIAGRLERVCKKDVEIS 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG +++P +HRD+ +W + +EF+P RF + P+ L F GPR+C Sbjct: 385 GVFIPKGTVVMVPTFTLHRDQSLW-PEPEEFRPERFSRKNKDSIN-PYTYLPFGTGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F+++ K L +LQ FSF Sbjct: 443 IGMRFAIMNMKLALVRVLQNFSF 465
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 89.7 bits (221), Expect = 7e-18 Identities = 52/146 (35%), Positives = 83/146 (56%), Gaps = 1/146 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQ-RKTVADM 480 A P+ Q +L+ EV KE + L+KLK M V+ E+LRL+ A F R+ + + Sbjct: 337 ALNPKIQSKLQDEVDKECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNT 396 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 +G + G+ ++I +H DK VWG+D +EFKP R+ + +T L+F GP Sbjct: 397 VIGEQIVEAGVDVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLT----PQQAYLSFGAGP 452 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSF 222 R C+G F++LE K L+ +L+K++F Sbjct: 453 RVCLGMRFALLEQKGLLSHILKKYTF 478
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 89.7 bits (221), Expect = 7e-18 Identities = 57/152 (37%), Positives = 84/152 (55%), Gaps = 5/152 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFETLRLYSPA-LFMQRKTVAD 483 PE Q++L++EV +E PDP ++KLK M V+ E LR+Y A L RK + Sbjct: 346 PEIQKKLQEEVDRE----CPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKK 401 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 V +++ +G + + +H D +VWGDDA EFKP R++ G G L F MG Sbjct: 402 TNVLGVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETG-DELFYAKGGYLPFGMG 460 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 PR CIG +M+E K L +L+K++F S + Sbjct: 461 PRICIGMRLAMMEEKLLLTHILKKYTFDTSTE 492
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 89.4 bits (220), Expect = 1e-17 Identities = 64/181 (35%), Positives = 89/181 (49%), Gaps = 2/181 (1%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A PE QER R+EV G S + L ++ TM + ET RL + R Sbjct: 331 CLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSK 390 Query: 485 DMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 +T LP GI +V+ I +H + VW + F PLRF + P+ L FS Sbjct: 391 PLTFPDGCTLPAGITVVLSIWGLHHNPAVW-KNPKVFDPLRFSQE-NSDQRHPYAYLPFS 448 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPLDK 129 G R+CIGQ F+M+E K T+AL+L F T P + F LKPK G+ + ++ L + Sbjct: 449 AGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKLSE 508 Query: 128 C 126 C Sbjct: 509 C 509
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 88.6 bits (218), Expect = 2e-17 Identities = 64/177 (36%), Positives = 97/177 (54%), Gaps = 5/177 (2%) Frame = -1 Query: 647 PEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV LK+ + + + L +L +TM + E+LRL+ PA F+ R D+ Sbjct: 348 PEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIV 407 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKGI +I I +H + VW D + + P RF + + P + FS GP Sbjct: 408 LPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFRF-DPENSKGRSPLAFIPFSAGP 465 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI-FTLKPKFGLQVFVRPLD 132 R+CIGQ F+M E K LALML F F PD+ + ++ + GL + V PL+ Sbjct: 466 RNCIGQAFAMAEMKVVLALMLLHFRFL--PDHTEPRRKLELIMRAEGGLWLRVEPLN 520
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 88.6 bits (218), Expect = 2e-17 Identities = 60/176 (34%), Positives = 90/176 (51%), Gaps = 2/176 (1%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE Q+R RKE+ G S N L+K+ TM + E LR+Y P + R+ + + Sbjct: 336 ATNPEHQQRCRKEIQSLLGDGTSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPV 395 Query: 479 TV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 T LPKGI +++ +H + VW + + F P RF G+++ H L FS G Sbjct: 396 TFPDGRSLPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFA---PGSSRHSHSFLPFSGG 451 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 R+CIG+ F+M E K +AL L +F P V P+ LK K G+ + ++ L Sbjct: 452 ARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVLKSKNGIHLHLKKL 507
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 88.6 bits (218), Expect = 2e-17 Identities = 52/146 (35%), Positives = 84/146 (57%), Gaps = 1/146 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQ-RKTVADMTVG 471 PE Q++L++EV +E + ++KLK M V+ E LR+Y A + RK + + V Sbjct: 346 PEIQKKLQEEVDRECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVL 405 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 +++ KG + + +H D +VWG+DA+EF+P R+++G G L F MGPR C Sbjct: 406 GVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESG-DELFYAKGGYLPFGMGPRIC 464 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLS 213 IG +M+E K L +L+K++F S Sbjct: 465 IGMRLAMMEKKMLLTHILKKYTFETS 490
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 88.2 bits (217), Expect = 2e-17 Identities = 57/172 (33%), Positives = 85/172 (49%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 A P+ ++ + E+ GM+ P + L KL T L E+ R +S + R+ V D Sbjct: 291 ALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDI 350 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + ++ +G +VIPI +H D W D D F P RF T + + L F G R Sbjct: 351 IDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDRPRCAY--LPFGGGRR 407 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVR 141 CIGQ+F+++E A+M Q F+F L+P Y TL+PK G+ V R Sbjct: 408 ICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGR 459
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 88.2 bits (217), Expect = 2e-17 Identities = 57/172 (33%), Positives = 85/172 (49%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 A P+ ++ + E+ GM+ P + L KL T L E+ R +S + R+ V D Sbjct: 291 ALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDI 350 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + ++ +G +VIPI +H D W D D F P RF T + + L F G R Sbjct: 351 IDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTDRPRCAY--LPFGGGRR 407 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVR 141 CIGQ+F+++E A+M Q F+F L+P Y TL+PK G+ V R Sbjct: 408 ICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGR 459
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 88.2 bits (217), Expect = 2e-17 Identities = 48/147 (32%), Positives = 88/147 (59%), Gaps = 5/147 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ F ++P +AL +++ + MV+ ETLR++ A ++R D+ + Sbjct: 36 PDVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERLCKKDVEIH 95 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFSMG 303 + +PKG +++P+ ++H + E W + +EF+P RF K+GI P+ L F G Sbjct: 96 GVSIPKGTTVMVPLFVLHNNPEFW-PEPEEFRPERFSKKNKDGIN-----PYVYLPFGTG 149 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 PR+C+G F+++ K L +LQ FSF Sbjct: 150 PRNCVGMRFALMNIKLALVRILQNFSF 176
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 87.8 bits (216), Expect = 3e-17 Identities = 58/160 (36%), Positives = 89/160 (55%), Gaps = 5/160 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFETLRLYSPALFMQ-RKTVAD 483 PE Q++L++EV +E PDP L+KLK M V+ ETLRLY A + RK + Sbjct: 346 PEIQKKLQEEVDRE----CPDPEVTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKS 401 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 TV +K+ +G + +H D + WG++A+EFKP R+++G A L F +G Sbjct: 402 TTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWESG-DEQAVAKGAYLPFGLG 460 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 183 PR CIG + +E K LA +L+K+S + + H P+ + Sbjct: 461 PRICIGMRLAYMEEKMLLAQILKKYSLETTFE-THIPLKL 499
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 87.8 bits (216), Expect = 3e-17 Identities = 62/181 (34%), Positives = 88/181 (48%), Gaps = 2/181 (1%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A PE Q+R R E+ G S L+++ TM + ETLRL P + R+ Sbjct: 329 CLALNPEHQDRCRTEIRSILGDGSSITWEQLDEIPYTTMCIKETLRLIPPIPSISRELSK 388 Query: 485 DMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 +T+ LP G+ +V+ I +H + VW D F PLRF + P L FS Sbjct: 389 PLTLPDGHSLPAGMTVVLSIWGLHHNPAVW-KDPKVFDPLRFTKE-NSEQRHPCAFLPFS 446 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPLDK 129 GPR+CIGQ F+MLE K +AL L +F A L+PK G+ + ++ L + Sbjct: 447 SGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLRPKHGIYLHLKKLPE 506 Query: 128 C 126 C Sbjct: 507 C 507
>CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450 reductase 2| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1054 Score = 87.4 bits (215), Expect = 4e-17 Identities = 57/180 (31%), Positives = 91/180 (50%), Gaps = 5/180 (2%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPA----LFMQRK 495 C PE ++ ++E + +P+ + +LK + MVL ETLRLY A L+ + Sbjct: 282 CLLTHPEKLKKAQEEADRVLTDDTPEYKQIQQLKYIRMVLNETLRLYPTAPAFSLYAKED 341 Query: 494 TVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVP-HGLL 318 TV G + KG + + IP +HRD+ WG DA++F+P RF++ + +P H Sbjct: 342 TVLG---GEYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERFED----PSSIPHHAYK 394 Query: 317 AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 F G R+CIG F++ EA L L+L+ F Y + T+KP ++ V+P Sbjct: 395 PFGNGQRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIKEALTIKPD-DFKITVKP 453
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 87.4 bits (215), Expect = 4e-17 Identities = 50/146 (34%), Positives = 79/146 (54%), Gaps = 1/146 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 A P+ QE++ +E+ +EFG + L +LK M V+ E LRLY A + RK + Sbjct: 340 AVNPKIQEKVIEEIAREFGTSEVEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTT 399 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 TV +K+ G+ + + +H D E+WG+D EFKP R+ K + L F +GP Sbjct: 400 TVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKPERWSTDEPLEHKGAY--LPFGLGP 457 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSF 222 R CIG +++E K L +L+ ++F Sbjct: 458 RQCIGMRLAIMEQKILLTHLLKNYTF 483
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 87.0 bits (214), Expect = 5e-17 Identities = 55/169 (32%), Positives = 89/169 (52%), Gaps = 8/169 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFETLRLYSPALFMQ-RKTVAD 483 PE Q +L++EV +E PDP L+KLK + V+ ETLRLY RK + + Sbjct: 344 PEIQTKLQEEVDRE----CPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRE 399 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 T+ + +G+ I + +H + +WG+D ++FKP R++NG + + F G Sbjct: 400 TTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSG 459 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---FTLKPK 165 PR CIG + +E K LA +L+++SF + + PV + TL P+ Sbjct: 460 PRQCIGMRLAQMEQKILLAQILKEYSFRTTKN-TQIPVKLVGKLTLSPE 507
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 86.7 bits (213), Expect = 6e-17 Identities = 47/143 (32%), Positives = 82/143 (57%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYS-PALFMQRKTVADMTVG 471 PE Q++L++E+ +E S + L+KLK M ++ ETLRLY + R+ + +G Sbjct: 346 PEVQKKLQEEIERECIEPSISFDHLSKLKYMDCIIKETLRLYPLGTMANSRRCMRATKLG 405 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 ++++ G + + +H D ++WGDDA EFKP R+ + G ++F +GPR C Sbjct: 406 NVEVEVGTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQKGGYISFGLGPRQC 465 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 +G + +E K LA +L+K++F Sbjct: 466 VGMRLAYMEEKMLLAHILRKYTF 488
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 86.7 bits (213), Expect = 6e-17 Identities = 48/143 (33%), Positives = 82/143 (57%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ + ++P + + ++ + MVL ETLRLY +QR D+ + Sbjct: 326 PDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEIN 385 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG ++IP ++H D + W + +EF+P RF G+ P+ L F GPR+C Sbjct: 386 GIYIPKGSTVIIPSYVLHHDPQHW-PEPEEFQPERFSKENKGSID-PYVYLPFGNGPRNC 443 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F+++ K L +LQ FSF Sbjct: 444 IGMRFALMNMKLALIKVLQNFSF 466
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 86.7 bits (213), Expect = 6e-17 Identities = 48/143 (33%), Positives = 83/143 (58%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ + ++P + + +++ + MVL ETLRLY ++R D+ + Sbjct: 326 PDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVCKKDVEIN 385 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG ++IP +HRD + W + +EF+P RF G+ P+ L F GPR+C Sbjct: 386 GVFMPKGSVVMIPSYALHRDPQHW-PEPEEFRPERFSKENKGSID-PYVYLPFGNGPRNC 443 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F+++ K L +LQ FSF Sbjct: 444 IGMRFALMNMKLALTKVLQNFSF 466
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 86.3 bits (212), Expect = 8e-17 Identities = 62/179 (34%), Positives = 93/179 (51%), Gaps = 5/179 (2%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A PE Q+R R E+ + G S L+++ TM + E LRLY+P + + R Sbjct: 329 CLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDK 388 Query: 485 DMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV-PHGLLAF 312 +T LP GI + I I +H + W +D F PLRF + K+ P+ + F Sbjct: 389 PITFPDGRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFSR--ENSEKIHPYAFIPF 445 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI--FTLKPKFGLQVFVR 141 S G R+CIGQ+F+++E K +AL L +F L+PD+ P + LK K G+ VF + Sbjct: 446 SAGLRNCIGQHFAIIECKVAVALTLLRFK--LAPDHSRPPQPVRQVVLKSKNGIHVFAK 502
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 86.3 bits (212), Expect = 8e-17 Identities = 45/143 (31%), Positives = 85/143 (59%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P Q++L++E+ F ++P +AL +++ + MV+ ETLR++ A ++R D+ + Sbjct: 325 PHVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERVCKKDVEIH 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG +++P+ ++H + E+W + +EF+P RF + P+ L F GPR+C Sbjct: 385 GVTIPKGTTVLVPLFVLHNNPELW-PEPEEFRPERFSKNNKDSIN-PYVYLPFGTGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 +G F+++ K L +LQ FSF Sbjct: 443 LGMRFAIMNIKLALVRILQNFSF 465
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 85.9 bits (211), Expect = 1e-16 Identities = 60/173 (34%), Positives = 89/173 (51%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 P+ QER R+E+ G S N L+++ TM + E LRLY P + R+ +T Sbjct: 341 PKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP 400 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LPKGI +++ I +H + +VW + + F P RF G+A+ H L FS G R+ Sbjct: 401 DGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFA---PGSAQHSHAFLPFSGGSRN 456 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K AL L +F P + P+ LK K G+ + +R L Sbjct: 457 CIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRL 509
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 85.5 bits (210), Expect = 1e-16 Identities = 62/173 (35%), Positives = 87/173 (50%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 PE Q R R+E+ G S L+K+ TM + E LRLY P + K + +T Sbjct: 342 PEHQHRCREEIQGLLGDGASITWEHLDKMPYTTMCIKEALRLYPPVPGVGSKLSSPVTFP 401 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LPKGI I + I +H + +VW + + F P RF G+A+ H L FS G R+ Sbjct: 402 DGRSLPKGIIITLSIYGLHHNPKVW-PNPEVFDPSRFA---PGSARHSHAFLPFSGGSRN 457 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P V P+ LK K G+ + +R L Sbjct: 458 CIGKQFAMNELKVAVALTLVRFELLPDPTRVPIPITRLVLKSKNGIHLRLRKL 510
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 84.3 bits (207), Expect = 3e-16 Identities = 58/179 (32%), Positives = 86/179 (48%), Gaps = 6/179 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNK---LKEMTMVLFETLRLYSPALFMQRKTVA 486 A P+ QE+L +EV +F + P P + L + MVL ETLR+Y PA R+ Sbjct: 359 ATNPDCQEKLLREV-DDFSKKHPSPEHCSLQQGLPYLDMVLSETLRMYPPAFRFTREAAR 417 Query: 485 DMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSM 306 D V ++P G + + + +H D + W + F P RF + P L F Sbjct: 418 DCEVLGQRIPAGTVLEVAVGALHHDPKHW-PHPETFDPERF-TAEAQRLQQPFTYLPFGA 475 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---FTLKPKFGLQVFVRP 138 GPRSC+G +LE K TL +L+KF F P+ P+ + L PK G+ + + P Sbjct: 476 GPRSCLGVQLGLLEIKLTLLHILRKFRFEACPE-TQVPLQLESKSALSPKNGVYIRIVP 533
>C13B1_CAEEL (O17624) Putative cytochrome P450 cyp-13B1 (EC 1.14.-.-)| Length = 527 Score = 84.0 bits (206), Expect = 4e-16 Identities = 46/141 (32%), Positives = 80/141 (56%), Gaps = 1/141 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFM-QRKTVADMTVG 471 PE + ++EV G ++ + + KLK + V+ E+LRLY A F R+ V T+G Sbjct: 340 PEKMKLAQEEVDTVVGSENVSYDDMTKLKYLDAVVRESLRLYPVAWFACSRECVKPTTLG 399 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + + KG+ I + +HR KE+WG++AD+F P R+ + +++ + F GPR C Sbjct: 400 DIYIDKGVKIEADVMSLHRSKEIWGENADDFVPERW---LEPSSRHTMSWIPFGAGPRQC 456 Query: 290 IGQNFSMLEAKSTLALMLQKF 228 +G + EAK+ LA +L+++ Sbjct: 457 VGMRLGLSEAKTALAHLLRRY 477
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 83.6 bits (205), Expect = 5e-16 Identities = 54/155 (34%), Positives = 83/155 (53%), Gaps = 4/155 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE Q+RL++E+ G P L +LK M V+ E+LRL+ P + R D+ Sbjct: 331 PEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVE 390 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + +P G + I ++ RD E + + DEF+P RF + P+ + FS GPR Sbjct: 391 IRGKHIPAGTNFTMGIFVLLRDPEYF-ESPDEFRPERFDADVPQIH--PYAYIPFSAGPR 447 Query: 296 SCIGQNFSMLEAKSTLALMLQKFS-FTLSPDYVHA 195 +CIGQ F+MLE KST++ +L+ F L P+ H+ Sbjct: 448 NCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHS 482
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 83.6 bits (205), Expect = 5e-16 Identities = 49/147 (33%), Positives = 82/147 (55%), Gaps = 5/147 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L +E+ K ++ P + + +++ + MV+ ETLRLY A ++R + D + Sbjct: 325 PDVQKKLHQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLRLYPVANRIERMSKKDFEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFSMG 303 + PKG ++IP +HRD + W + DEF+P RF K I P+ + F G Sbjct: 385 GMSFPKGTLVMIPSFALHRDSKYW-PEPDEFRPERFSKKNKENID-----PYIYMPFGNG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 PR+CIG+ +++ K L +LQ FSF Sbjct: 439 PRNCIGRRMALMNLKLALIRLLQNFSF 465
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 83.6 bits (205), Expect = 5e-16 Identities = 49/146 (33%), Positives = 84/146 (57%), Gaps = 4/146 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L+KE+ ++P +A+ +++ + MV+ ETLRL+ A+ ++R D+ + Sbjct: 325 PDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF---KNGITGAAKVPHGLLAFSMGP 300 + +PKG +VIP +H D + W + +EF+P RF K+ I P+ F GP Sbjct: 385 GVFIPKGSMVVIPTYALHHDPKYW-TEPEEFRPERFSKKKDSID-----PYIYTPFGTGP 438 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSF 222 R+CIG F+++ K L +LQ FSF Sbjct: 439 RNCIGMRFALMNMKLALIRVLQNFSF 464
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 83.6 bits (205), Expect = 5e-16 Identities = 47/148 (31%), Positives = 84/148 (56%), Gaps = 1/148 (0%) Frame = -1 Query: 662 CSAYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 C A P+ Q++L++E+ + ++P + + +++ + MVL ETLRLY ++R Sbjct: 321 CLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKK 380 Query: 485 DMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSM 306 D+ + + +PKG ++IP +H D + W + +EF+P RF G+ P+ + F + Sbjct: 381 DVELNGVYIPKGSTVMIPSYALHHDPQHW-PEPEEFQPERFSKENKGSID-PYLYMPFGI 438 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSF 222 GPR+CIG F+ + K L ++Q FSF Sbjct: 439 GPRNCIGMRFAFMTMKLALTKVMQNFSF 466
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 83.6 bits (205), Expect = 5e-16 Identities = 60/174 (34%), Positives = 88/174 (50%), Gaps = 8/174 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQ-SPDPNALNK-LKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 P+ QERL KEV G +P+ ++L + L + MV+ ETLR+Y PA R+ D V Sbjct: 361 PDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEV 420 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV---PHGLLAFSMG 303 ++P G + I + +H D E W + + F P RF T A++ P L F G Sbjct: 421 LGQRIPAGTVLEIAVGALHHDPEHW-PNPETFDPERF----TAEARLQRRPFTYLPFGAG 475 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---FTLKPKFGLQV 150 PRSC+G +L K T+ +L KF F SP+ P+ + L PK G+ + Sbjct: 476 PRSCLGVRLGLLVVKLTILQVLHKFRFEASPE-TQVPLQLESKSALGPKNGVYI 528
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 82.8 bits (203), Expect = 9e-16 Identities = 46/143 (32%), Positives = 82/143 (57%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L+ E+ + ++P + + +++ + MVL ETLRLY A ++R D+ + Sbjct: 326 PDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVELN 385 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG ++IP +H D + W + +EF+P RF G+ P+ L F GPR+C Sbjct: 386 GVYIPKGSTVMIPSYALHHDPQHW-SEPEEFQPERFSKENKGSID-PYVYLPFGNGPRNC 443 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 +G F+++ K L ++Q FSF Sbjct: 444 LGMRFALMNMKLALTKIMQNFSF 466
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 82.4 bits (202), Expect = 1e-15 Identities = 48/147 (32%), Positives = 81/147 (55%), Gaps = 5/147 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ K ++ P + + +++ + MV+ ETLRLY ++R + D + Sbjct: 325 PDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFSMG 303 + PKG ++IP +HRD + W + DEF+P RF K I P+ + F G Sbjct: 385 GMSFPKGTGVMIPSFALHRDSKYW-PEPDEFRPERFSKKNKENID-----PYIYMPFGNG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 PR+CIG +++ K L +LQ FSF Sbjct: 439 PRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 82.4 bits (202), Expect = 1e-15 Identities = 48/147 (32%), Positives = 81/147 (55%), Gaps = 5/147 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ K ++ P + + +++ + MV+ ETLRLY ++R + D + Sbjct: 325 PDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFSMG 303 + PKG ++IP +HRD + W + DEF+P RF K I P+ + F G Sbjct: 385 GMSFPKGTGVMIPSFALHRDSKYW-PEPDEFRPERFSKKNKENID-----PYIYMPFGNG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 PR+CIG +++ K L +LQ FSF Sbjct: 439 PRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 81.6 bits (200), Expect = 2e-15 Identities = 57/173 (32%), Positives = 88/173 (50%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 P+ Q+R R+EV G S + L+++ TM + E LRLY P + R+ +T Sbjct: 340 PKHQQRCREEVQSVLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFP 399 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LPKGI + + I +H + +VW + + F P RF + + H L FS G R+ Sbjct: 400 DGRSLPKGIQVTLSIYGLHHNPKVW-PNPEVFDPSRFA---PDSPRHSHSFLPFSGGARN 455 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P V P+ LK K G+ ++++ L Sbjct: 456 CIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLVLKSKNGIYLYLKKL 508
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 80.9 bits (198), Expect = 3e-15 Identities = 48/145 (33%), Positives = 82/145 (56%), Gaps = 1/145 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A P Q++L+ E+ + ++P +AL +++ + MV+ E+LRLY A + R + D+ Sbjct: 322 ATRPNVQKKLQNEIDRALPNKAPVTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKDV 381 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKG + IPI +HR+ E W + +EF P RF G+ P+ L F GP Sbjct: 382 EINGVFIPKGTVVTIPIYPLHRNPEYW-LEPEEFNPERFSKENKGSID-PYVYLPFGNGP 439 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFS 225 R+CIG F+++ K + +LQ F+ Sbjct: 440 RNCIGMRFALISMKLAVIGVLQNFN 464
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 80.9 bits (198), Expect = 3e-15 Identities = 53/144 (36%), Positives = 81/144 (56%), Gaps = 4/144 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV + + P+ + L +L +TM + E+LRL+ PA+ + R+ D+ Sbjct: 350 PEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQDIV 409 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKG VI I +H + VW D + F P RF + + P + FS GP Sbjct: 410 LPDGRVIPKGNICVISIFGIHHNPSVW-PDPEVFDPFRFDSE-NRQKRSPLSFIPFSAGP 467 Query: 299 RSCIGQNFSMLEAKSTLALMLQKF 228 R+CIGQ F+M E K +AL L +F Sbjct: 468 RNCIGQTFAMNEMKVVVALTLLRF 491
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 80.9 bits (198), Expect = 3e-15 Identities = 47/145 (32%), Positives = 81/145 (55%), Gaps = 1/145 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A P+ Q++L+ E+ ++P + L +++ + MV+ ETLRLY A ++R D+ Sbjct: 322 AIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDV 381 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + L +PKG ++IP +H+D + W + +EF+P RF + P+ L F GP Sbjct: 382 EINGLFIPKGTVVMIPTFALHKDPKYW-PEPEEFRPERFSKKNQDSIN-PYMYLPFGSGP 439 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFS 225 R+CIG F+++ K L +LQ F+ Sbjct: 440 RNCIGMRFALINMKVALVRVLQNFT 464
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 80.9 bits (198), Expect = 3e-15 Identities = 63/175 (36%), Positives = 83/175 (47%), Gaps = 9/175 (5%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNK---LKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE QERL KEV F + P P N L + MV+ ETLR+Y PA R+ D Sbjct: 361 PECQERLLKEV-DLFMEKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCE 419 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV---PHGLLAFSM 306 V +P G + I + +H D E W + + F P RF T A++ P L F Sbjct: 420 VLGQHIPAGSVLEIAVGALHHDPEHW-PNPETFDPERF----TAEARLQQKPFTYLPFGA 474 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---FTLKPKFGLQV 150 GPRSC+G +L K TL +L KF F P+ P+ + L PK G+ V Sbjct: 475 GPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPE-TQVPLQLESKSALCPKNGVYV 528
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 80.5 bits (197), Expect = 4e-15 Identities = 50/153 (32%), Positives = 84/153 (54%), Gaps = 5/153 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMT---MVLFETLRLYSPALFMQRKTVA 486 A PE+QER +E+ F + ++M ++L E++R+ P + R+T Sbjct: 300 AMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQ 359 Query: 485 DMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGITGAAKVPHGLLAF 312 D+ + + + +PKG+ I I I MHR K++WG DA+ F P F + I K P+ + F Sbjct: 360 DLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQD--KHPYAYIPF 417 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 213 + G R+CIG ++++ AK TLA +L+ + F S Sbjct: 418 TKGIRNCIGWRYALISAKVTLAKLLRNYRFKTS 450
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 80.5 bits (197), Expect = 4e-15 Identities = 53/165 (32%), Positives = 85/165 (51%), Gaps = 4/165 (2%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 A PE Q + +E++ G + P + LN L M + + ETLR+Y + RK + Sbjct: 334 ALYPECQRKCVEEIVSVLGKDTETPVTYDLLNNLNYMDLCIKETLRMYPSVPLLGRKVLQ 393 Query: 485 DMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV-PHGLLAFS 309 + + +P G I I + R +++ + + FKP RF + +T A K+ PH + FS Sbjct: 394 ECEINGKIIPAGTNIGISPLFLGRSEDI-SSEPNTFKPERF-DVVTSAEKLNPHAYIPFS 451 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 174 GPR+CIGQ F+MLE K+ A +L+ + + +PV I L Sbjct: 452 AGPRNCIGQKFAMLEIKAIAANVLRHYEIEFVGNAEESPVLIAEL 496
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 80.5 bits (197), Expect = 4e-15 Identities = 58/173 (33%), Positives = 86/173 (49%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 PE QER R+EV G S + L+++ TM + E LRLYSP + R+ + +T Sbjct: 335 PEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFP 394 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 +PKGI + I I +H + W + F P RF + + H L FS G R+ Sbjct: 395 DGRSIPKGIRVTILIYGLHHNPSYW-PNPKVFDPSRFS---PDSPRHSHAYLPFSGGARN 450 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P + P+ LK K G+ + ++ L Sbjct: 451 CIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKL 503
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 80.5 bits (197), Expect = 4e-15 Identities = 48/143 (33%), Positives = 78/143 (54%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ ++P + + +++ + MVL ETLRLY ++R D+ + Sbjct: 326 PDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNETLRLYPIGNRLERVCKKDIELD 385 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 L +PKG + IP +H D + W +EF P RF G+ P+ L F GPR+C Sbjct: 386 GLFIPKGSVVTIPTYALHHDPQHW-PKPEEFHPERFSKENKGSID-PYVYLPFGNGPRNC 443 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F+++ K L +LQ FSF Sbjct: 444 IGMRFALMNMKLALTKVLQNFSF 466
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 77.8 bits (190), Expect(2) = 5e-15 Identities = 54/144 (37%), Positives = 81/144 (56%), Gaps = 4/144 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE Q ++ +E+ + FG +S P L KLK + V+ ETLR++ R D Sbjct: 349 PEVQRKVDQELDEVFG-RSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCE 407 Query: 476 VGSLKLPKGI-AIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 VG K+ KG AI+IP + HRD + D +EF+P RF + P+ + FS GP Sbjct: 408 VGGYKVTKGTEAIIIPYAL-HRDPRYF-PDPEEFRPERFFPE-NSQGRHPYAYVPFSAGP 464 Query: 299 RSCIGQNFSMLEAKSTLALMLQKF 228 R+CIGQ F+++E K+ LA +L++F Sbjct: 465 RNCIGQKFAVMEEKTILACILRQF 488 Score = 22.7 bits (47), Expect(2) = 5e-15 Identities = 8/17 (47%), Positives = 11/17 (64%) Frame = -3 Query: 681 LTWSVYLLSIYPRMARK 631 + WS+YLL P + RK Sbjct: 338 INWSLYLLGTNPEVQRK 354
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 80.1 bits (196), Expect = 6e-15 Identities = 56/176 (31%), Positives = 86/176 (48%), Gaps = 2/176 (1%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE Q+ RKE+ G S + L+K+ TM + E LR+Y P + R + Sbjct: 336 ATNPEHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTPV 395 Query: 479 TV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 T LPKGI +++ +H + VW + + F P RF +++ H L FS G Sbjct: 396 TFPDGRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRFA---PESSRHSHSFLPFSGG 451 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 R+CIG+ F+M E K +AL L +F P + P+ LK K G+ + ++ L Sbjct: 452 ARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKNGIYLRLKKL 507
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 80.1 bits (196), Expect = 6e-15 Identities = 61/175 (34%), Positives = 90/175 (51%), Gaps = 4/175 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV + + P+ + L +L +TM + E+LRL+ P L + R D+ Sbjct: 348 PEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQDIV 407 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKG VI I +H + VW D + + P RF + + P + FS GP Sbjct: 408 LPDGRVIPKGNICVISIFGVHHNPSVW-PDPEVYNPFRF-DPENPQKRSPLAFIPFSAGP 465 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 R+CIGQ F+M E K LAL L +F L D L+ + GL + V PL Sbjct: 466 RNCIGQTFAMSEIKVALALTLLRFC-VLPDDKEPRRKPELILRAEGGLWLRVEPL 519
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 80.1 bits (196), Expect = 6e-15 Identities = 46/147 (31%), Positives = 84/147 (57%), Gaps = 5/147 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++++KE+ ++P + + +L+ + MV+ ETLRL+ A+ ++R D+ + Sbjct: 325 PDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFSMG 303 + +PKG+ ++IP ++H D + W + ++F P RF K+ I P+ F G Sbjct: 385 GMFIPKGVVVMIPSYVLHHDPKYW-REPEKFLPERFSKKNKDNID-----PYIYTPFGSG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 PR+CIG F+++ K L +LQ FSF Sbjct: 439 PRNCIGMRFALVNMKLALVRVLQNFSF 465
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 80.1 bits (196), Expect = 6e-15 Identities = 59/177 (33%), Positives = 83/177 (46%), Gaps = 8/177 (4%) Frame = -1 Query: 656 AYTPEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A P+ QE+L +EV KE M + L + MV+ ETLR+Y PA R+ D Sbjct: 358 ATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQD 417 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPH---GLLAF 312 V ++P G + + + +H D E W + F P RF T A+ H L F Sbjct: 418 CEVLGQRIPAGAVLEMAVGALHHDPEHW-PSPETFNPERF----TAEARQQHRPFTYLPF 472 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---FTLKPKFGLQV 150 GPRSC+G +LE K TL +L KF F P+ P+ + L PK G+ + Sbjct: 473 GAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPE-TQVPLQLESKSALGPKNGVYI 528
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 79.3 bits (194), Expect = 1e-14 Identities = 62/179 (34%), Positives = 92/179 (51%), Gaps = 5/179 (2%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 A PE+QER R+EV + + P+ + L +L +TM + E+LRL+ P + R Sbjct: 345 ANDPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQ 404 Query: 485 DMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK-NGITGAAKVPHGLLAF 312 D+ + + +PKGI +I I +H + VW D + + P RF I ++ P + F Sbjct: 405 DILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYNPFRFDPENIKDSS--PLAFIPF 461 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 S GPR+CIGQ F+M E K LAL L +F L D L+ + GL + V PL Sbjct: 462 SAGPRNCIGQTFAMSEMKVALALTLLRFRL-LPDDKEPRRQPELILRAEGGLWLRVEPL 519
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 79.3 bits (194), Expect = 1e-14 Identities = 56/173 (32%), Positives = 87/173 (50%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 P+ Q+R R+EV G S + L+++ TM + E LRLY P + R+ +T Sbjct: 340 PDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFP 399 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LPKG+ + + I +H + +VW + + F P RF + + H L FS G R+ Sbjct: 400 DGRSLPKGVQVTLSIYGLHHNPKVW-PNPEVFDPSRFA---PDSPRHSHSFLPFSGGARN 455 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P V P+ LK K G+ + ++ L Sbjct: 456 CIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKKL 508
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 79.3 bits (194), Expect = 1e-14 Identities = 46/142 (32%), Positives = 82/142 (57%), Gaps = 1/142 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L+ E+ + ++P +AL ++ + MV+ E+LRLY A+ ++R + D+ + Sbjct: 325 PDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG ++IPI +HR+ E W + EF P RF G P+ + F GPR+C Sbjct: 385 GVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPERFSKENKGNID-PYIYMPFGNGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFS 225 IG F+++ K + +LQ F+ Sbjct: 443 IGMRFALISIKLAVIGVLQNFT 464
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 79.3 bits (194), Expect = 1e-14 Identities = 59/177 (33%), Positives = 91/177 (51%), Gaps = 8/177 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA---LNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE Q ++ +E+++ G P + L +LK M V+ E+LR+Y P + RK D Sbjct: 287 PEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFK 346 Query: 476 V-----GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAF 312 G +P G I+I I +HR E + + DEF P R +NG A P ++ F Sbjct: 347 YTHSVHGDGVIPAGSEIIIGIFGVHRQPETF-PNPDEFIPERHENGSRVA---PFKMIPF 402 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVR 141 S GPR+CIGQ F+ LE K LA +++++ V V+I L+ + G Q+ +R Sbjct: 403 SAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVNI-VLRSETGFQLGMR 458
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 79.0 bits (193), Expect = 1e-14 Identities = 57/173 (32%), Positives = 85/173 (49%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 PE Q R R+E+ G S L+++ TM + E LRLY P + R+ + +T Sbjct: 341 PEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEALRLYPPVPGVGRQLSSPVTFP 400 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LPKG+ + + I +H + +VW + + F P F G+A+ H L FS GPR+ Sbjct: 401 DGRSLPKGVIVTLSIYALHHNPKVW-PNPEVFDPFPFA---PGSARHSHAFLPFSGGPRN 456 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P V LK G+ + +R L Sbjct: 457 CIGKQFAMNELKVAVALTLVRFELLPDPKRVPDQKPRLVLKSSNGIHLRLRKL 509
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 79.0 bits (193), Expect = 1e-14 Identities = 46/142 (32%), Positives = 79/142 (55%), Gaps = 1/142 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L E+ ++P + L ++ + MV+ E LRLY A ++R + + + Sbjct: 325 PDVQKKLHDEIDSALPNKAPVTYDVLMGMEYLDMVINEGLRLYPIANRLERISKKAVEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 L +PKGI +++P +HRD E W + +EF+P RF G+ P+ + F GPR+C Sbjct: 385 GLFIPKGITVMVPTYPLHRDPEYW-PEPEEFRPERFSKENKGSID-PYVYMPFGNGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFS 225 IG F++L K + +LQ F+ Sbjct: 443 IGMRFALLSMKLAVVSVLQNFT 464
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 79.0 bits (193), Expect = 1e-14 Identities = 52/177 (29%), Positives = 94/177 (53%), Gaps = 4/177 (2%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNA-LNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE ++L+KE+ F ++P L +++ + V+ E+LRLY A ++R A + Sbjct: 323 ATNPEVMKKLQKEIDATFPNKAPVQYVPLMEMEYLDCVVNESLRLYPIAARLERVAKATV 382 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 V L +PK + +++P +HRD E+W + ++FKP RF P+ + F GP Sbjct: 383 EVNGLVIPKDMVVMVPTWPLHRDPELW-PEPEKFKPERFSKENKDTFD-PYTYMPFGAGP 440 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT---LKPKFGLQVFVRP 138 R+CIG F+++ K + +LQ + F++ + P ++ L PK +Q+ + P Sbjct: 441 RNCIGMRFALVMMKLAVVEILQTYDFSVCKE-TEVPFEMDVQGFLAPKRPIQLKLTP 496
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 78.6 bits (192), Expect = 2e-14 Identities = 60/179 (33%), Positives = 89/179 (49%), Gaps = 8/179 (4%) Frame = -1 Query: 647 PEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV L++ + + L +L +TM + E+LRL+ P + R+ D+ Sbjct: 348 PEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIV 407 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVPHGLLAF 312 + + +PKG+ +I I H + VW D D F P K+ + P + F Sbjct: 408 LPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPENIKD------RSPLAFIPF 461 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 S GPR+CIGQ F+M E K LAL L +F L D L+ + GL + V PL Sbjct: 462 SAGPRNCIGQTFAMNEMKVALALTLLRFR-VLPDDKEPRRKPELILRAEGGLWLRVEPL 519
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 78.6 bits (192), Expect = 2e-14 Identities = 56/173 (32%), Positives = 84/173 (48%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 PE Q+R R+EV G S + L ++ TM + E LRLY P + + R+ + +T Sbjct: 338 PEHQQRCREEVQSILGDGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTFP 397 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 +PKGI I I +H + W + F P RF ++ H L FS G R+ Sbjct: 398 DGRSIPKGITATISIYGLHHNPRFW-PNPKVFDPSRFA---PDSSHHSHAYLPFSGGSRN 453 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P + P+ LK K G+ + ++ L Sbjct: 454 CIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARLVLKSKNGIHLCLKKL 506
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 78.6 bits (192), Expect = 2e-14 Identities = 61/176 (34%), Positives = 91/176 (51%), Gaps = 5/176 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV + + P+ + L +L +TM + E+LRL+ P + R D+ Sbjct: 348 PEYQERCRQEVQELLRGREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDIL 407 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK-NGITGAAKVPHGLLAFSMG 303 + + +PKGI +I I +H + VW D + + P RF I ++ P + FS G Sbjct: 408 LPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYDPFRFDPENIKDSS--PLAFIPFSAG 464 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 PR+CIGQ F+M E K LAL L +F L D L+ + GL + V PL Sbjct: 465 PRNCIGQTFAMSEMKVALALTLLRFRL-LPDDKEPRRQPELILRAEGGLWLRVEPL 519
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 78.6 bits (192), Expect = 2e-14 Identities = 57/173 (32%), Positives = 85/173 (49%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 PE Q R R+E+ G S L+++ TM + E LRLY P + R+ +T Sbjct: 341 PEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEALRLYPPVPSVTRQLSKPVTFP 400 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LPKG+ + + I +H + +VW + + F P RF +A H L FS G R+ Sbjct: 401 DGRSLPKGVILFLSIYGLHYNPKVW-QNPEVFDPFRFA---PDSAYHSHAFLPFSGGARN 456 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P + P+ LK K G+ + +R L Sbjct: 457 CIGKQFAMRELKVAVALTLVRFELLPDPTRIPIPIARVVLKSKNGIHLRLRKL 509
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 78.2 bits (191), Expect = 2e-14 Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 1/151 (0%) Frame = -1 Query: 632 RLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKLP 456 +L++E+ F ++P AL ++ + VL E+LRLY A ++R + + + +P Sbjct: 335 KLQEEIDTVFPNKAPIQYEALMQMDYLDCVLNESLRLYPIAPRLERVAKKTVEINGIVIP 394 Query: 455 KGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNF 276 K +++P +HRD E+W D +EFKP RF + P+ + F GPR+CIG F Sbjct: 395 KDCIVLVPTWTLHRDPEIW-SDPEEFKPERFSKENKESID-PYTYMPFGAGPRNCIGMRF 452 Query: 275 SMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 183 +++ K + +LQ F+F++ D P+++ Sbjct: 453 ALIMIKLAMVEILQSFTFSVC-DETEIPLEM 482
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 78.2 bits (191), Expect = 2e-14 Identities = 62/176 (35%), Positives = 90/176 (51%), Gaps = 5/176 (2%) Frame = -1 Query: 647 PEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV LK+ + + + L +L +TM L E+LRL+ P R D+ Sbjct: 348 PEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVV 407 Query: 476 V-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + S +PKG I I +H + VW D + + P RF + + P + FS GP Sbjct: 408 LPDSRVIPKGNVCNINIFAIHHNPSVW-PDPEVYDPFRF-DPENAQKRSPMAFIPFSAGP 465 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-APVDIFTLKPKFGLQVFVRPL 135 R+CIGQ F+M E K LAL L + F + PD+ L+ + GL + V PL Sbjct: 466 RNCIGQKFAMAEMKVVLALTLLR--FRILPDHREPRRTPEIVLRAEDGLWLRVEPL 519
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 78.2 bits (191), Expect = 2e-14 Identities = 50/151 (33%), Positives = 83/151 (54%), Gaps = 7/151 (4%) Frame = -1 Query: 647 PEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 P+ Q++L++E+ L + + D L K++ + MV+ ETLRLY A ++R D+ Sbjct: 323 PDVQQKLQEEIDTLLPNKELATYD--TLVKMEYLDMVVNETLRLYPIAGRLERVCKKDVD 380 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFS 309 + +PKG +++P +HRD + W + DEF+P RF K+ I P+ F Sbjct: 381 INGTFIPKGTIVMMPTYALHRDPQHW-TEPDEFRPERFSKKNKDNIN-----PYIYHPFG 434 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 GPR+C+G F+++ K L ++Q FSF L Sbjct: 435 AGPRNCLGMRFALMNIKLALVRLMQNFSFKL 465
>CP56_YEAST (P21595) Cytochrome P450-DIT2 (EC 1.14.14.-) (Cytochrome P450 56)| Length = 489 Score = 78.2 bits (191), Expect = 2e-14 Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 13/181 (7%) Frame = -1 Query: 665 ICSAYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSP-ALFMQRKTV 489 + + Y+ EWQE+LRKEV DP L L + LFE +R+Y P + + R T Sbjct: 308 LLAKYSNEWQEKLRKEV-----NGITDPKGLADLPLLNAFLFEVVRMYPPLSTIINRCTT 362 Query: 488 ADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT------GAAKVP 330 +G+ + +PKG+ + D + WG AD+FKP R+ + I AK Sbjct: 363 KTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNR 422 Query: 329 HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-----APVDIFTLKPK 165 + F G R+C+G+ ++ E + +LA ML++F ++L P++ P+ LK K Sbjct: 423 CAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCPLNLKLK 482 Query: 164 F 162 F Sbjct: 483 F 483
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 77.8 bits (190), Expect = 3e-14 Identities = 60/179 (33%), Positives = 90/179 (50%), Gaps = 14/179 (7%) Frame = -1 Query: 647 PEWQERLRKEV------LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 PE QE + +E+ FG+ PD + KL + V+ ETLRL R+T Sbjct: 317 PEHQEAVFEELNGVFPDAGHFGITYPD---MQKLDYLERVIKETLRLIPAIPITARETKN 373 Query: 485 DMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 D+ + + + +PKG+ I I + HR+ EVWG DAD F P F K P+ + F+ Sbjct: 374 DVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFL-AENMEQKHPYAYIPFA 432 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSF---TLSPDYVHAPVDIFTLK----PKFGLQ 153 G R+CIG ++M+ +K L +L+ + TL D V+ VD T+K P+ LQ Sbjct: 433 RGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKDLVY--VDNMTMKLAEYPRLKLQ 489
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 77.8 bits (190), Expect = 3e-14 Identities = 54/180 (30%), Positives = 90/180 (50%), Gaps = 8/180 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFETLRLYSPALFMQRKTVADMT 477 PE+QER+ +E+ FG P + L +M + + ++LRL+ M R D+ Sbjct: 362 PEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVN 421 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 +G +P G +I +HR+ V+ ++F P F A + P + FS GPR Sbjct: 422 IGGKIVPAGTQAIIMTYALHRNPRVF-PKPEQFNPDNFLPE-NCAGRHPFAYIPFSAGPR 479 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI-----FTLKPKFGLQVFVRPLD 132 +CIGQ F++LE K+ ++ +L+K+ + V D+ L+PK GL+V + P D Sbjct: 480 NCIGQKFAILEEKAVISTVLRKYKI----EAVDRREDLTLLGELILRPKDGLRVKITPRD 535
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 77.8 bits (190), Expect = 3e-14 Identities = 56/173 (32%), Positives = 83/173 (47%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 PE Q R R+E+ G S L+++ TM + E +RLY P + R + +T Sbjct: 342 PEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEAMRLYPPVPAISRDLSSPVTFP 401 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LPKG + + I +H + VW + + F P RF G+A+ H L FS G R+ Sbjct: 402 DGRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDPGRFT---PGSARHSHAFLPFSGGARN 457 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P + P LK G+ + +R L Sbjct: 458 CIGKQFAMNELKVAVALTLVRFELLPDPTRIPKPTARLVLKSNNGIHLRLRKL 510
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 77.8 bits (190), Expect = 3e-14 Identities = 48/148 (32%), Positives = 75/148 (50%), Gaps = 6/148 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 PE QE KEV F P LN + + V+ E+LRL+ ++ R+ D + Sbjct: 329 PEIQEEAYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQDFEL 388 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVPHGLLAFSM 306 G +P G I +P +HR+ E++ + + D F P R N + P+ + FS Sbjct: 389 GGYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVN------RHPYAYIPFSA 442 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSF 222 GPR+CIGQ F++LE K L+ +L+ + F Sbjct: 443 GPRNCIGQRFALLEEKVVLSYLLRHYRF 470
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 77.8 bits (190), Expect = 3e-14 Identities = 46/144 (31%), Positives = 81/144 (56%), Gaps = 3/144 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMT---MVLFETLRLYSPALFMQRKTVADMT 477 P+ Q++L++E+ + + + + +K+ EM MVL ETLRLY ++R D+ Sbjct: 323 PDVQKKLQEEI--DIALPNKARPSYDKVMEMEYLDMVLNETLRLYPIGSRLERVCKQDVE 380 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + + +PKG +++P+ +H D + W + ++F+P RF G+ P+ L F GPR Sbjct: 381 MDGVFVPKGSIVMVPVFALHYDPQYW-PEPEKFRPERFSKENKGSID-PYIFLPFGNGPR 438 Query: 296 SCIGQNFSMLEAKSTLALMLQKFS 225 +CIG F+++ K L +LQ FS Sbjct: 439 NCIGMRFALMNMKLALTKVLQNFS 462
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 77.4 bits (189), Expect = 4e-14 Identities = 60/176 (34%), Positives = 91/176 (51%), Gaps = 5/176 (2%) Frame = -1 Query: 647 PEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV LK+ + + + L L +TM + E+LRL+ P + R D+ Sbjct: 348 PEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIV 407 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKGI +I + H + VW D + + P RF + + P + FS GP Sbjct: 408 LPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF-DPENIKERSPLAFIPFSAGP 465 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-APVDIFTLKPKFGLQVFVRPL 135 R+CIGQ F+M E K LAL L + F + PD+ L+ + GL + V PL Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLR--FRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 77.0 bits (188), Expect = 5e-14 Identities = 47/146 (32%), Positives = 79/146 (54%), Gaps = 1/146 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A P+ Q++L+ E+ ++ + L +++ + MV+ ETLRLY A ++R D+ Sbjct: 322 AIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDV 381 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKG ++IP +H+D W + +EF+P RF P+ L F GP Sbjct: 382 EINGVFIPKGTVVMIPTFALHKDPHYW-PEPEEFRPERFSKKNQDNIN-PYMYLPFGNGP 439 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSF 222 R+CIG F+++ K L +LQ FSF Sbjct: 440 RNCIGMRFALMNMKVALFRVLQNFSF 465
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 77.0 bits (188), Expect = 5e-14 Identities = 46/147 (31%), Positives = 83/147 (56%), Gaps = 5/147 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ ++P + + +++ + MV+ ETLRL+ A+ ++R D+ + Sbjct: 325 PDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFSMG 303 + +PKG ++IP +HRD + W + ++F P RF K+ I P+ F G Sbjct: 385 GMFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPERFSKKNKDNID-----PYIYTPFGSG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 PR+CIG F+++ K L +LQ FSF Sbjct: 439 PRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 77.0 bits (188), Expect = 5e-14 Identities = 46/147 (31%), Positives = 83/147 (56%), Gaps = 5/147 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ ++P + + +++ + MV+ ETLRL+ A+ ++R D+ + Sbjct: 324 PDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN 383 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFSMG 303 + +PKG ++IP +HRD + W + ++F P RF K+ I P+ F G Sbjct: 384 GMFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPERFSKKNKDNID-----PYIYTPFGSG 437 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 PR+CIG F+++ K L +LQ FSF Sbjct: 438 PRNCIGMRFALMNMKLALIRVLQNFSF 464
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 77.0 bits (188), Expect = 5e-14 Identities = 57/173 (32%), Positives = 84/173 (48%), Gaps = 2/173 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 PE QER R+EV G S + L+++ TM + E LRLY P + R+ + +T Sbjct: 338 PEHQERCREEVQSILGDGTSVTWDHLDQIPYTTMCIKEALRLYPPVPSVSRELSSPVTFP 397 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 +PKGI I I +H + W + F P RF + + H L FS G R+ Sbjct: 398 DGRSIPKGITTTILIYGLHHNPSYW-PNPKVFDPSRFS---PDSPRHSHAYLPFSGGARN 453 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 CIG+ F+M E K +AL L +F P + P+ LK K G+ + ++ L Sbjct: 454 CIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLKSKNGIHLRLKKL 506
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 76.3 bits (186), Expect = 8e-14 Identities = 51/161 (31%), Positives = 79/161 (49%), Gaps = 3/161 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE Q++ +E+ G P LN+L + + + ETLR+Y + RK + D Sbjct: 336 PEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCE 395 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + +P G I I + R +E++ + + FKP RF T P+ + FS GPR Sbjct: 396 INGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKLNPYAYIPFSAGPR 454 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 174 +CIGQ F+MLE K+ +A +L+ + D PV I L Sbjct: 455 NCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAEL 495
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 76.3 bits (186), Expect = 8e-14 Identities = 51/161 (31%), Positives = 79/161 (49%), Gaps = 3/161 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE Q++ +E+ G P LN+L + + + ETLR+Y + RK + D Sbjct: 336 PEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCE 395 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + +P G I I + R +E++ + + FKP RF T P+ + FS GPR Sbjct: 396 INGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVVTTAEKLNPYAYIPFSAGPR 454 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 174 +CIGQ F+MLE K+ +A +L+ + D PV I L Sbjct: 455 NCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAEL 495
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 76.3 bits (186), Expect = 8e-14 Identities = 45/144 (31%), Positives = 82/144 (56%), Gaps = 2/144 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ ++P + + +++ + MV+ ETLRL+ A+ ++R D+ + Sbjct: 325 PDVQQKLQEEIDAVLPNKAPATYDTVLQMEYLDMVVNETLRLFPLAMRLERVCKKDVEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGITGAAKVPHGLLAFSMGPRS 294 + +PKG+ ++IP +H D + W + ++F P RF KN P+ F GPR+ Sbjct: 385 GVFIPKGVVVMIPSYALHYDPKYW-TEPEKFLPERFSKNNKDNID--PYIYTPFGTGPRN 441 Query: 293 CIGQNFSMLEAKSTLALMLQKFSF 222 CIG F+++ K L +LQ FSF Sbjct: 442 CIGMRFALMNMKLALIRVLQNFSF 465
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 75.9 bits (185), Expect = 1e-13 Identities = 46/152 (30%), Positives = 86/152 (56%), Gaps = 5/152 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE ++L++E+ F ++P L +++ + V+ E+LRL+ A ++R A + Sbjct: 321 ATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAV 380 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAF 312 + + +PK + ++IP +HRD E+W + + FKP RF K+ I P+ + F Sbjct: 381 EINGIVIPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKKNKDNID-----PYIYMPF 434 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 GPR+CIG F+++ K + +LQ++SF++ Sbjct: 435 GSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 75.9 bits (185), Expect = 1e-13 Identities = 41/143 (28%), Positives = 80/143 (55%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ ++P + + +++ + MV+ ETLR++ A+ ++R D+ + Sbjct: 325 PDVQQKLQEEIDTVLPNKAPPTYDTVLQMEYLDMVVNETLRIFPIAMRLERVCKKDVEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG+ ++IP +H D + W + ++F P RF P+ F GPR+C Sbjct: 385 GIFIPKGVVVMIPSYALHHDPKYW-PEPEKFLPERFSKKNNDNID-PYIYTPFGSGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F+++ K + +LQ FSF Sbjct: 443 IGMRFALMNMKLAIIRVLQNFSF 465
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 75.5 bits (184), Expect = 1e-13 Identities = 46/152 (30%), Positives = 86/152 (56%), Gaps = 5/152 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE ++L++E+ F ++P L +++ + V+ E+LRL+ A ++R A + Sbjct: 321 ATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLRLFPIAARLERVAKAAV 380 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAF 312 + + +PK + ++IP +HRD E+W + + FKP RF K+ I P+ + F Sbjct: 381 EINGVVIPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKKNKDNID-----PYIYMPF 434 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 GPR+CIG F+++ K + +LQ++SF++ Sbjct: 435 GSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 75.5 bits (184), Expect = 1e-13 Identities = 56/176 (31%), Positives = 90/176 (51%), Gaps = 7/176 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN----ALNKLKEMTMVLFETLRLYSPALFMQRKTV 489 A P+ Q RL+ E+ + ++ D A++ +K + MV+ E+LRLY PA+F RK V Sbjct: 351 ATNPDVQNRLQDEI--DQSLEENDGKLTYEAIHSMKYLDMVVSESLRLYPPAIFTDRKCV 408 Query: 488 ADMTVG---SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLL 318 + + S L G A+ IPI +H D + + + ++F P RF + K P L Sbjct: 409 KNYRLPMEPSYTLEPGDAVWIPIYAIHHDPKYY-PNPEKFDPERFSDENKDNIK-PFTYL 466 Query: 317 AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQV 150 F GPR+CIG F+++E+K L +L +F+ + P+ I K F + V Sbjct: 467 PFGSGPRNCIGNRFALMESKIALVHLLCRFNLKV---VSKTPIPIKITKKGFNMTV 519
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 75.1 bits (183), Expect = 2e-13 Identities = 49/149 (32%), Positives = 74/149 (49%), Gaps = 1/149 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 PEWQ+R R E + G D +L +L+ + +V+ E++RL +P + R+TV D + Sbjct: 323 PEWQQRCRDESDRH-GDGPLDIESLEQLESLDLVMNESIRLVTPVQWAMRQTVRDTELLG 381 Query: 467 LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCI 288 LPKG ++ + HR E+W D F P RF + + F G CI Sbjct: 382 YYLPKGTNVIAYPGMNHRLPEIWTDPL-TFDPERFTEPRNEHKRHRYAFTPFGGGVHKCI 440 Query: 287 GQNFSMLEAKSTLALMLQKFSFTLS-PDY 204 G F LE K+ L +L+++ LS PDY Sbjct: 441 GMVFDQLEIKTILHRLLRRYRLELSRPDY 469
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 74.7 bits (182), Expect = 2e-13 Identities = 43/143 (30%), Positives = 80/143 (55%), Gaps = 1/143 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ Q++L++E+ ++P +AL +++ + MV+ ETLRL+ + R D+ + Sbjct: 325 PDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN 384 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 + +PKG+A+++PI +H D + W + ++F P RF + + + + F GPR+C Sbjct: 385 GVFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPERFSKKNKDSIDL-YRYIPFGAGPRNC 442 Query: 290 IGQNFSMLEAKSTLALMLQKFSF 222 IG F++ K + LQ FSF Sbjct: 443 IGMRFALTNIKLAVIRALQNFSF 465
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 74.7 bits (182), Expect = 2e-13 Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 8/179 (4%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + PE + +++KE+ + G ++P N L + + E LR+ A L + K D Sbjct: 319 HNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVLRIRPVAPLLIPHKANIDS 378 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPH-GLLAFSMG 303 ++G +PK ++I + +H DK W D D F P RF + P L F G Sbjct: 379 SIGEFAIPKDTHVIINLWALHHDKNEW-DQPDRFMPERFLDPTGSHLITPTPSYLPFGAG 437 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD-----YVHAPVDIFTLKPKFGLQVFVR 141 PRSCIG+ + E +AL+LQ+F F +S D V P +F + P F +++ VR Sbjct: 438 PRSCIGEALARQELFIFMALLLQRFDFDVSDDKQLPCLVGDPKVVFLIDP-FKVKITVR 495
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 74.3 bits (181), Expect = 3e-13 Identities = 59/176 (33%), Positives = 91/176 (51%), Gaps = 5/176 (2%) Frame = -1 Query: 647 PEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QER R+EV LK+ + + + L +L +TM + E+LRL+ P + R D+ Sbjct: 348 PEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIV 407 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKGI +I + H + VW D + + P RF + + P + FS GP Sbjct: 408 LPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF-DPKNIKERSPLAFIPFSAGP 465 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-APVDIFTLKPKFGLQVFVRPL 135 R+CIGQ F+M E K L L L + F + PD+ L+ + GL + V PL Sbjct: 466 RNCIGQAFAMAEMKVVLGLTLLR--FRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 73.9 bits (180), Expect = 4e-13 Identities = 58/175 (33%), Positives = 89/175 (50%), Gaps = 4/175 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP---DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE+QE+ R+EV + + P + + L +L +TM + E+LRL+ P + R D Sbjct: 348 PEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFV 407 Query: 476 VGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +PKGI +I I +H + VW D + + P RF N + P + FS GP Sbjct: 408 LPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRF-NQENIKERSPLAFIPFSAGP 465 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 R+CIGQ F+M E K LAL L F + ++ L+ + GL + V PL Sbjct: 466 RNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELI-LRAEGGLWLRVEPL 519
>CP52W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2)| Length = 519 Score = 73.9 bits (180), Expect = 4e-13 Identities = 51/165 (30%), Positives = 81/165 (49%), Gaps = 14/165 (8%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTM---VLFETLRLYSPALFMQRKTVADMT 477 PE + LR+ V+ +FG +P +LK+ + V+ E LRL+ R+ +AD T Sbjct: 332 PEVYDELREAVIADFGSADAEPPTFEQLKQCKVLQNVIREVLRLHPNVPLNFREAIADTT 391 Query: 476 VGS---------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG 324 + + +PKG + +M R+ +WG D+ F+P R+ N A Sbjct: 392 FPTGGGPNGDQPIFVPKGQKVFYATYVMQRNAGIWGPDSTSFRPDRW-NEPREALASGWD 450 Query: 323 LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS--FTLSPDYVHA 195 + F+ GPR C+GQ F++ EA TL + Q+FS L PD + A Sbjct: 451 YIPFNGGPRICLGQQFALTEASYTLVRICQEFSRIEVLHPDVITA 495
>CP52C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)| (Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A) (Cytochrome P-450ALK) Length = 522 Score = 73.2 bits (178), Expect = 7e-13 Identities = 56/186 (30%), Positives = 83/186 (44%), Gaps = 15/186 (8%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVLFETLRLYSPALFMQRK 495 A P+ +LR+EV FG+ L K + + VL ETLR+Y R Sbjct: 336 ARNPKIWNKLREEVEVNFGLGDEARVDEISFETLKKCEYLKAVLNETLRMYPSVPINFRT 395 Query: 494 TVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 342 D T+ + +PKG ++V + HR K+ +G+DA EF+P R+ T Sbjct: 396 ATRDTTLPRGGGKDGNSPIFVPKGSSVVYSVYKTHRLKQFYGEDAYEFRPERWFEPST-- 453 Query: 341 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKF 162 K+ L F+ GPR C+GQ F++ EA +A + Q F S D + P L Sbjct: 454 RKLGWAYLPFNGGPRICLGQQFALTEASYVIARLAQMFEHLESKDETYPPNKCIHLTMNH 513 Query: 161 GLQVFV 144 VF+ Sbjct: 514 NEGVFI 519
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 67.8 bits (164), Expect(2) = 8e-13 Identities = 50/173 (28%), Positives = 80/173 (46%), Gaps = 29/173 (16%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 PE + + E+ G P ++ KL+ + +++ E LRL+ + R+T+ T+ Sbjct: 379 PEKIRKAQAEIDAVLGQGPPTYESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPG 438 Query: 467 --------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-----KNGITG------ 345 K+PKG I I + +HR W D+ +F+P RF NGI G Sbjct: 439 GHKGEKEGHKVPKGTDIFISVYNLHRSPYFW-DNPHDFEPERFLRTKESNGIEGWAGFDP 497 Query: 344 ----AAKVPHGLLA------FSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 A P+ ++A F GPR CIG F+++E+ LA++ QKF L Sbjct: 498 SRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVALAMLFQKFDVEL 550 Score = 25.4 bits (54), Expect(2) = 8e-13 Identities = 11/18 (61%), Positives = 13/18 (72%) Frame = -3 Query: 681 LTWSVYLLSIYPRMARKA 628 LTW+V+LLS P RKA Sbjct: 368 LTWAVFLLSQNPEKIRKA 385
>C81E1_GLYEC (P93147) Cytochrome P450 81E1 (EC 1.14.13.89) (Isoflavone| 2'-hydroxylase) (P450 91A4) (CYP GE-3) Length = 499 Score = 72.8 bits (177), Expect = 9e-13 Identities = 50/146 (34%), Positives = 79/146 (54%), Gaps = 2/146 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 PE ++++ E+ G D + L KL + V+ ETLRLY+PA L + T + + Sbjct: 322 PEVLKKVKDELDTHVGQDRLVDESDLPKLTYLKNVINETLRLYTPAPLLLPHSTSDECNI 381 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 G K+P+ ++I +HRD E+W +A FKP RF+ G + L+AF MG R+ Sbjct: 382 GGYKVPQDTIVLINAWAIHRDPELW-TEATTFKPERFEK--KGELEK---LIAFGMGRRA 435 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTL 216 C G+ ++ TLAL++Q F + L Sbjct: 436 CPGEGLAIRAISMTLALLIQCFDWKL 461
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 72.4 bits (176), Expect = 1e-12 Identities = 50/152 (32%), Positives = 79/152 (51%), Gaps = 4/152 (2%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A P+ QERLR EVL Q +++ ++ + V+ ETLR Y + R++ + Sbjct: 312 ALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKE 371 Query: 482 MTV--GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 + +L L G I+IP+ +H D E++ D ++F P RF+ A+ P L F Sbjct: 372 YQIPNSNLILEPGSKIIIPVHSIHHDPELY-PDPEKFDPSRFEPEEI-KARHPFAYLPFG 429 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 213 GPR+CIG+ F L+ K L +L+ F F+ S Sbjct: 430 EGPRNCIGERFGKLQVKVGLVYLLRDFKFSRS 461
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 72.0 bits (175), Expect = 2e-12 Identities = 55/171 (32%), Positives = 83/171 (48%), Gaps = 1/171 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 PE RL+ EV + G + D L +L+ ++ VL E+LRLY PA R + + Sbjct: 322 PEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLID 381 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 +++P ++ +M R + + +D F P RF GA K FS+G RSC Sbjct: 382 GVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFG---PGAPKPRFTYFPFSLGHRSC 437 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 IGQ F+ +E K +A +LQ+ F L P + TLKP + +RP Sbjct: 438 IGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKPLDPVLCTLRP 488
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 72.0 bits (175), Expect = 2e-12 Identities = 48/143 (33%), Positives = 76/143 (53%), Gaps = 3/143 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 PE QE+ +E+ + N LNKLK + + ET+RL+ M R+T + + Sbjct: 342 PEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFIKETMRLFPSVPAMGRETTRETEL 401 Query: 473 GS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + L LPKG I + + +HR+ E W D +EF+P RF + + + FS G R Sbjct: 402 SNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPE-NSQNRHTYAYIPFSAGQR 459 Query: 296 SCIGQNFSMLEAKSTLALMLQKF 228 +CIGQ F+M E K+ + +L++F Sbjct: 460 NCIGQKFAMQEMKTLMVALLKQF 482
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 71.6 bits (174), Expect = 2e-12 Identities = 55/171 (32%), Positives = 83/171 (48%), Gaps = 1/171 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 PE RL+ EV + G + D L +L+ ++ VL E+LRLY PA R + + Sbjct: 322 PEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLID 381 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 +++P ++ +M R + + +D F P RF GA K FS+G RSC Sbjct: 382 GVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFG---PGAPKPRFTYFPFSLGHRSC 437 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 IGQ F+ +E K +A +LQ+ F L P + TLKP + +RP Sbjct: 438 IGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRP 488
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reductase 1| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1061 Score = 71.6 bits (174), Expect = 2e-12 Identities = 49/162 (30%), Positives = 80/162 (49%), Gaps = 2/162 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 P+ ++ +EV + +P + +L + M+L E+LRL+ A D +G Sbjct: 287 PDKLKKAYEEVDRVLTDAAPTYKQVLELTYIRMILNESLRLWPTAPAFSLYPKEDTVIGG 346 Query: 467 -LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVP-HGLLAFSMGPRS 294 + I + IP +HRD++ WG DA+EF+P RF++ +VP H F G R+ Sbjct: 347 KFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEH----QDQVPHHAYKPFGNGQRA 402 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKP 168 CIG F++ EA L ++L+ F+ +Y TLKP Sbjct: 403 CIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLKP 444
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 71.2 bits (173), Expect = 3e-12 Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 7/177 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA---LNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE Q+R+ +E+ + G + P L LK + V+ ET+RLY P + R ++ Sbjct: 336 PEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELE 395 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KNGITGAAKVPHGLLAFS 309 +G +P +I + + HRD + D F+P RF + G A VP FS Sbjct: 396 IGDKTIPANTSIYLVLYYAHRDANYFPDPL-SFRPERFLEDQEQGHNTFAYVP-----FS 449 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 GP++CIGQ F++LE K ++ +L +F L P+ F L+ G+ V +RP Sbjct: 450 AGPKNCIGQKFAVLEMKVLISKVL-RFYELLPLGEELKPMLNFILRSASGINVGLRP 505
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 71.2 bits (173), Expect = 3e-12 Identities = 54/159 (33%), Positives = 81/159 (50%), Gaps = 11/159 (6%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNK--LKEMT---MVLFETLRLYSPALFMQRKT 492 A P+ Q+RLR+E+ E + + D LN L +MT VL ETLR + + R+T Sbjct: 330 ALQPDIQQRLREEI--ESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRET 387 Query: 491 VADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVP 330 D + + L KGI +IP+ +H D E++ + D F P KN + P Sbjct: 388 TKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKN------RHP 441 Query: 329 HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 213 L F GPR+CIG F ++AK L +L++F F++S Sbjct: 442 MAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVS 480
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 71.2 bits (173), Expect = 3e-12 Identities = 45/150 (30%), Positives = 79/150 (52%), Gaps = 4/150 (2%) Frame = -1 Query: 665 ICSAYTPEWQERLRKEVLKEF---GMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRK 495 I A P++Q+ + +E+ + F G L KL ++ VL ET+RL + R+ Sbjct: 306 ILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQ 365 Query: 494 TVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLL 318 T + + + +P+G+ ++I I HR+K++WG A+ F P F A+ P+ L Sbjct: 366 TSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPE-NKRARPPYSYL 424 Query: 317 AFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 FS G ++C+G S++ AK LA +L+ + Sbjct: 425 PFSKGKKTCLGWKLSLISAKLALAKILRNY 454
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 70.9 bits (172), Expect = 4e-12 Identities = 44/146 (30%), Positives = 81/146 (55%), Gaps = 6/146 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA------LNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 P+ QE + +E++ G PDP+A L +LK + V+ ET+RL+ P + R Sbjct: 336 PKVQECIYEELVSVLG---PDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPE 392 Query: 485 DMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSM 306 D+ +G + +P +I++ ++RD E + D FKP R+ + T + P + FS Sbjct: 393 DLKIGEITIPGNTSILLMPYYVYRDPEYFPDPL-VFKPERWMDMKTTSNTPPLAYIPFSS 451 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKF 228 GP++CIGQ F+ L+ K+ ++ +++ + Sbjct: 452 GPKNCIGQKFANLQMKALISKVIRHY 477
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 69.7 bits (169), Expect(2) = 4e-12 Identities = 46/142 (32%), Positives = 72/142 (50%), Gaps = 2/142 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 PE Q+++ E+ FG L KL+ + V+ ETLRL+ R D V Sbjct: 349 PEVQQKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEV 408 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 ++ KG VI +HRD + + +EF+P RF + P+ + FS GPR+ Sbjct: 409 AGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPE-NAQGRHPYAYVPFSAGPRN 466 Query: 293 CIGQNFSMLEAKSTLALMLQKF 228 CIGQ F+++E K+ L+ +L+ F Sbjct: 467 CIGQKFAVMEEKTILSCILRHF 488 Score = 21.2 bits (43), Expect(2) = 4e-12 Identities = 7/17 (41%), Positives = 11/17 (64%) Frame = -3 Query: 681 LTWSVYLLSIYPRMARK 631 + WS+YLL P + +K Sbjct: 338 INWSLYLLGCNPEVQQK 354
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 69.3 bits (168), Expect(2) = 5e-12 Identities = 46/142 (32%), Positives = 72/142 (50%), Gaps = 2/142 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 PE Q+++ E+ FG L KL+ + V+ ETLRL+ R D V Sbjct: 349 PEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEV 408 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 ++ KG VI +HRD + + +EF+P RF + P+ + FS GPR+ Sbjct: 409 AGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPE-NAQGRHPYAYVPFSAGPRN 466 Query: 293 CIGQNFSMLEAKSTLALMLQKF 228 CIGQ F+++E K+ L+ +L+ F Sbjct: 467 CIGQKFAVMEEKTILSCILRHF 488 Score = 21.2 bits (43), Expect(2) = 5e-12 Identities = 7/17 (41%), Positives = 11/17 (64%) Frame = -3 Query: 681 LTWSVYLLSIYPRMARK 631 + WS+YLL P + +K Sbjct: 338 INWSLYLLGSNPEVQKK 354
>CP52F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)| (Alkane-inducible P450-ALK3) Length = 524 Score = 70.1 bits (170), Expect = 6e-12 Identities = 48/167 (28%), Positives = 77/167 (46%), Gaps = 15/167 (8%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 PE +LR+E+ FG+ +L + + + +L ETLR+Y R Sbjct: 341 PEIWSKLREEIEVNFGVGEESRVEEITFESLKRCEYLKAILNETLRMYPSVPVNSRTATR 400 Query: 485 DMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV 333 D T+ + +PKG + + HR +E +G DAD+F+P R+ T K+ Sbjct: 401 DTTLPRGGGPNGTDPIFIPKGSTVAYIVYKTHRLEEYYGKDADDFRPERWFEPST--KKL 458 Query: 332 PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAP 192 + F+ GPR C+GQ F++ EA + ++Q F SP V P Sbjct: 459 GWAYVPFNGGPRICLGQQFALTEASYVITRLVQMFETVSSPPDVEYP 505
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 70.1 bits (170), Expect = 6e-12 Identities = 47/150 (31%), Positives = 81/150 (54%), Gaps = 9/150 (6%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV-GS 468 Q+R+RKE + G + + ++ + + V+ ETLRLY+ + R+ + D V G Sbjct: 331 QDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGH 390 Query: 467 LK--LPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVPHGLLAFSM 306 K + KG+ ++IP MHRD++++ + + D F P R K + L F Sbjct: 391 PKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKE------RDSVEWLPFGD 444 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 GPR+CIG F ++A+S LAL++ +F F++ Sbjct: 445 GPRNCIGMRFGQMQARSGLALLINRFKFSV 474
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 69.7 bits (169), Expect = 8e-12 Identities = 45/145 (31%), Positives = 74/145 (51%), Gaps = 3/145 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFETLRLYSPALFMQRKTVADMT 477 PE Q+R R+EV G +P ++ +++++ + + ETLR+Y RK A+ T Sbjct: 336 PEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCT 395 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + +PKG ++I M R K+ + D FKP R+ G + + F G R Sbjct: 396 INDFFIPKGSDVIISPIYMGRCKDFFPDPM-VFKPDRWAIGAEPKIEAT-TFIPFMAGAR 453 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSF 222 SC+GQ ++M+ K LA +L+ F F Sbjct: 454 SCMGQRYAMVMLKMVLAHLLRNFLF 478
>C6A17_DROME (Q9V770) Probable cytochrome P450 6a17 (EC 1.14.-.-) (CYPVIA17)| Length = 501 Score = 69.3 bits (168), Expect = 1e-11 Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 4/148 (2%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPD--PNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSL 465 Q++LR+E+ FG + + + ++K + V+ ETLR Y + R T D + Sbjct: 327 QDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDP 386 Query: 464 K--LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 K + KG +VIP +H D +++ + + FKP RF + AA+ L F GPR+C Sbjct: 387 KYFIAKGTIVVIPALGIHYDPDIY-PEPEIFKPERFTDEEI-AARPSCTWLPFGEGPRNC 444 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLSPD 207 IG F M++ LA +++ + F++SP+ Sbjct: 445 IGLRFGMMQTCVGLAYLIRGYKFSVSPE 472
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 69.3 bits (168), Expect = 1e-11 Identities = 56/180 (31%), Positives = 83/180 (46%), Gaps = 3/180 (1%) Frame = -1 Query: 668 CICSAYTPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQR 498 C A PE Q R+ +EV G P L +LK + V+ E+LRL+ + R Sbjct: 328 CYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGR 387 Query: 497 KTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLL 318 D + +P ++I I RD + + D ++F P RF G P Sbjct: 388 YISQDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFSMERKGEIS-PFAYT 445 Query: 317 AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 FS GPR+CIGQ F+MLE KST++ M++ F + V PV L+ G+ ++P Sbjct: 446 PFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQ-PVLNVILRSTTGINCGLKP 504
>CP52B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA2)| (Alkane-inducible P450-ALK2) Length = 522 Score = 68.9 bits (167), Expect = 1e-11 Identities = 50/171 (29%), Positives = 84/171 (49%), Gaps = 16/171 (9%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGM------QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRK 495 A TP +LR+E+ +FG+ + +L + + VL E LRLY R Sbjct: 335 ARTPRVANKLREEIEDKFGLGQDARVEEISFESLKSCEYLKAVLNECLRLYPSVPQNFRV 394 Query: 494 TVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 342 + T+ + + KG ++ + HR+K+++G+DA EF+P R+ T Sbjct: 395 ATRNTTLPRGGGKDGLSPVLVRKGQTVMYSVYAAHRNKQIYGEDALEFRPERWFEPET-- 452 Query: 341 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS-FTLSPDYVHAP 192 K+ L F+ GPR C+GQ F++ EA +LQ+FS T+ P+ ++P Sbjct: 453 KKLGWAFLPFNGGPRICLGQQFALTEASYVTVRLLQEFSHLTMDPNTEYSP 503
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 68.9 bits (167), Expect = 1e-11 Identities = 54/172 (31%), Positives = 85/172 (49%), Gaps = 17/172 (9%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA------LNKLKE-MTMVLFETLRLYSPALFMQRKTV 489 PE +LR+E+ +FG+ PD L KL E + V+ ETLRLY R Sbjct: 335 PEVWSKLREEIGDKFGLD-PDSRIEDISFELLKLCEYLKAVINETLRLYPSVPRNGRFAA 393 Query: 488 ADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAK 336 A+ T+ + + KG ++ + + RD++ +G DA+EF+P R+ K Sbjct: 394 ANTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFE--PEVRK 451 Query: 335 VPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTLSPDYVHAPVDI 183 + L F+ GPR C+GQ F++ EA L ++Q F + LSPD + P + Sbjct: 452 LGWAFLPFNGGPRICLGQQFALTEASYVLVRLIQSFETLELSPDAPYPPAKL 503
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 68.9 bits (167), Expect = 1e-11 Identities = 52/171 (30%), Positives = 83/171 (48%), Gaps = 16/171 (9%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVLFETLRLYSP----ALFMQR 498 PE +LR+E+ +FG+ S L + + VL ETLRLY A F + Sbjct: 335 PEVWSKLRQEIGHKFGLDSYSRVEDISFELLKLCEYLKAVLNETLRLYPSVPRNARFAAK 394 Query: 497 KTVADMTVGS-----LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV 333 T G + + KG ++ + + RD++ +G DA+EF+P R+ K+ Sbjct: 395 NTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKDANEFRPERWFE--PEVRKL 452 Query: 332 PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTLSPDYVHAPVDI 183 L F+ GPR C+GQ F++ EA LA ++Q F + LSP+ + P + Sbjct: 453 GWAFLPFNGGPRICLGQQFALTEASYVLARLIQSFETLELSPEAAYPPAKL 503
>CP17A_RAT (P11715) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 68.9 bits (167), Expect = 1e-11 Identities = 45/152 (29%), Positives = 76/152 (50%), Gaps = 3/152 (1%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + PE +++++KE+ + G ++P N + L + + E LR+ A + + K D Sbjct: 319 HNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDS 378 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVP-HGLLAFSMG 303 ++G +PK +V+ + +H D+ W D D+F P RF + P L F G Sbjct: 379 SIGEFTVPKDTHVVVNLWALHHDENEW-DQPDQFMPERFLDPTGSHLITPTQSYLPFGAG 437 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 PRSCIG+ + E AL+LQ+F +S D Sbjct: 438 PRSCIGEALARQELFVFTALLLQRFDLDVSDD 469
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 68.6 bits (166), Expect = 2e-11 Identities = 53/169 (31%), Positives = 82/169 (48%), Gaps = 3/169 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 PE Q RLRKE+ ++ D +ALN L + ++ E LRLY+ R+T +G Sbjct: 313 PETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGG 372 Query: 467 LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCI 288 G+ + I + + DKE + D FKP R+ A + FS GP CI Sbjct: 373 RTYCAGVTLWINMYGLAHDKEYY-PDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCI 431 Query: 287 GQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---FTLKPKFGLQV 150 G+ +S+L K A ++++F LSP+ AP+ + LK + G+ V Sbjct: 432 GRRYSLLLMKLLTARLVREFQMELSPE--QAPLRLEAQMVLKAQQGINV 478
>CP139_MYCTU (P63719) Putative cytochrome P450 139 (EC 1.14.-.-)| Length = 430 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/172 (28%), Positives = 76/172 (44%), Gaps = 3/172 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 P E EV + G + P + L+ L + V+ ETLRLYSP + R+ + D+ Sbjct: 254 PGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDG 313 Query: 467 LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGITGAAKVPHGLLAFSMGPRSC 291 ++ G ++ + HR E+W + EF+PLR+ N PH + FS G C Sbjct: 314 HRIRAGRLLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRC 372 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLSPDYVH--APVDIFTLKPKFGLQVFVR 141 IG + E LA ++ + L H + L+P GL V +R Sbjct: 373 IGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIR 424
>CP139_MYCBO (P63720) Putative cytochrome P450 139 (EC 1.14.-.-)| Length = 430 Score = 68.2 bits (165), Expect = 2e-11 Identities = 49/172 (28%), Positives = 76/172 (44%), Gaps = 3/172 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 P E EV + G + P + L+ L + V+ ETLRLYSP + R+ + D+ Sbjct: 254 PGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRDLWFDG 313 Query: 467 LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGITGAAKVPHGLLAFSMGPRSC 291 ++ G ++ + HR E+W + EF+PLR+ N PH + FS G C Sbjct: 314 HRIRAGRLLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAADYRKPAPHEFIPFSGGLHRC 372 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLSPDYVH--APVDIFTLKPKFGLQVFVR 141 IG + E LA ++ + L H + L+P GL V +R Sbjct: 373 IGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAALRPWPGLTVEIR 424
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/153 (31%), Positives = 79/153 (51%), Gaps = 5/153 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPD--PNALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A PE Q R+R+EV K + L M V+ ETLR++ ++ R+T+ D Sbjct: 337 ALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLND 396 Query: 482 MTVGSLK---LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAF 312 V L K + ++IP +H D +++ D +EFKP R+ +G + + F Sbjct: 397 YAVPDHPKYILVKELFLIIPTHAIHHDPDIY-PDPEEFKPDRW-SGPRDSLQEQGTWFGF 454 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 213 +G RSCIG F+ L+ + LAL+L ++ F+L+ Sbjct: 455 GVGARSCIGIQFAQLQLRLALALLLSEYEFSLN 487
>CP4P1_DROME (Q9V558) Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)| Length = 513 Score = 68.2 bits (165), Expect = 2e-11 Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 3/143 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFG--MQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 P+ QE +E+ + + + D LNKLK + + ET RL+ M R+ V + + Sbjct: 340 PDKQELCYQEIQEHIDDDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETEL 399 Query: 473 GS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + L LPKG I I + +HR+ + W D +EF+P RF + + + FS G R Sbjct: 400 ANGLILPKGAQITIHVFDIHRNAKYW-DSPEEFRPERFLPE-NVQDRHTYAYVPFSAGQR 457 Query: 296 SCIGQNFSMLEAKSTLALMLQKF 228 +CIG+ ++M E K+ + ++L++F Sbjct: 458 NCIGKKYAMQEMKTLMVVLLKQF 480
>CP52E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)| (Alkane-inducible P450-ALK2-A) (CYP52A3-B) Length = 523 Score = 68.2 bits (165), Expect = 2e-11 Identities = 53/186 (28%), Positives = 81/186 (43%), Gaps = 15/186 (8%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVLFETLRLYSPALFMQRK 495 A P+ +LR+E+ FG+ L K + + VL ETLR+Y R Sbjct: 337 ARNPKIWNKLREEIEVNFGLGEEARVDEISFETLKKCEYLKAVLNETLRMYPSVPVNFRT 396 Query: 494 TVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 342 D T+ + +PKG ++V + HR +E +G DA EF+P R+ T Sbjct: 397 ATRDTTLPRGGGKDGTSPIFVPKGSSVVYTVYKTHRLEEYYGKDAYEFRPERWFEPST-- 454 Query: 341 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKF 162 K+ + F+ GPR C+GQ F++ EA + + Q F S D + P L Sbjct: 455 RKLGWAYVPFNGGPRICLGQQFALTEASYVITRLAQMFEHLESKDETYPPNKCIHLTMNH 514 Query: 161 GLQVFV 144 VF+ Sbjct: 515 NEGVFI 520
>C28C1_DROME (Q9VYT8) Probable cytochrome P450 28c1 (EC 1.14.-.-) (CYPXXVIIIC1)| Length = 505 Score = 67.8 bits (164), Expect = 3e-11 Identities = 48/153 (31%), Positives = 77/153 (50%), Gaps = 7/153 (4%) Frame = -1 Query: 647 PEWQERLRKEV-LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV- 474 P+ Q RL +E+ L G PD +AL L ++ E+LR+Y + + + + Sbjct: 320 PDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLRIYPAGGWASKTCTKEYELR 379 Query: 473 GS-----LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 GS LKL G +++PI +H D +++ + D F+P RF +G K L F Sbjct: 380 GSHHSEPLKLRPGDHVMVPIYALHNDPDLY-PEPDVFRPERFLDGGLKNCKQQGIFLGFG 438 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 GPR C+G + AK+ LA ++Q+F +SP Sbjct: 439 NGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSP 471
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 67.4 bits (163), Expect = 4e-11 Identities = 47/158 (29%), Positives = 77/158 (48%), Gaps = 4/158 (2%) Frame = -1 Query: 665 ICSAYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTM---VLFETLRLYSPALFMQRK 495 I A PE Q+ + +E+ + F + + L+ M V+ ETLRL F R+ Sbjct: 311 ILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRE 370 Query: 494 TVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLL 318 T+ D + S + +PKG+ I I I HR+++ WG D F P F + P+ + Sbjct: 371 TIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPD-NVRDRHPYAYI 429 Query: 317 AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY 204 FS G R+CIG + ++ +K L+ +L+ + S Y Sbjct: 430 PFSKGRRNCIGWKYGLMSSKLALSKILRNCKVSTSFRY 467
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 67.4 bits (163), Expect = 4e-11 Identities = 51/155 (32%), Positives = 80/155 (51%), Gaps = 8/155 (5%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPAL--FMQRKT 492 A + Q+RLR+EV + F D +AL + + VL ETLR Y + + R+T Sbjct: 322 AQNQQLQDRLREEVNEVFDQFKEDNISYDALMNIPYLDQVLNETLRKYPVGVGSALTRQT 381 Query: 491 VADMTVG---SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL 321 + D V LPKG + IP+ +H D E++ + +EF P RF + + Sbjct: 382 LNDYVVPHNPKYVLPKGTLVFIPVLGIHYDPELY-PNPEEFDPERFSPEMV-KQRDSVDW 439 Query: 320 LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 L F GPR+CIG F ++++ LAL+++ F FT+ Sbjct: 440 LGFGDGPRNCIGMRFGKMQSRLGLALVIRHFRFTV 474
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 67.4 bits (163), Expect = 4e-11 Identities = 50/163 (30%), Positives = 78/163 (47%), Gaps = 14/163 (8%) Frame = -1 Query: 647 PEWQERLRKEVLKEFG---MQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE LR+ VL EFG +++P L + K + V+ E LRL+ R+ + D Sbjct: 332 PEVYAELREAVLSEFGSTDVETPTFEQLKQCKVLQNVIREVLRLHPNVPLNFRQAIVDTK 391 Query: 476 VGS---------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG 324 + + + +PKG + M R ++WG DA F+P R+ N A Sbjct: 392 LPTGGGPNGDQPVFVPKGQNVFYSTYSMQRRTDIWGPDATTFRPDRW-NEPREALASGWD 450 Query: 323 LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS--FTLSPDYV 201 + F+ GPR C+GQ F++ EA T+ + Q+FS L PD + Sbjct: 451 YIPFNGGPRICLGQQFALTEASYTIVRICQEFSRIEVLHPDVI 493
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 67.0 bits (162), Expect = 5e-11 Identities = 51/164 (31%), Positives = 80/164 (48%), Gaps = 4/164 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 PE +++KEV + G L KL ++ VL ETLRL SP + + D +G Sbjct: 286 PEAYSKVQKEVDEVVGRGPVLVEHLTKLPYISAVLRETLRLNSPITAFGLEAIDDTFLGG 345 Query: 467 LKL-PKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAA--KVPHGLLAFSMGPR 297 L KG + + H D V+G+DAD+F P R + + P+ F G R Sbjct: 346 KYLVKKGEIVTALLSRGHVDPVVYGNDADKFIPERMLDDEFARLNKEYPNCWKPFGNGKR 405 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLS-PDYVHAPVDIFTLKP 168 +CIG+ F+ E+ + ++ Q F+FT++ P+Y T+KP Sbjct: 406 ACIGRPFAWQESLLAMVVLFQNFNFTMTDPNYALEIKQTLTIKP 449
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 66.6 bits (161), Expect = 7e-11 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 4/155 (2%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSP---DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 A PE QE + E+ + F + L +L + VL ETLRL F R+T+ Sbjct: 314 AMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLE 373 Query: 485 DMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 D+ + + + +PKG+ I I I R+ + WG +A +F P F + P+ + FS Sbjct: 374 DLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKI-HDRHPYAFIPFS 432 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY 204 G R+CIG + ++ +K L +L+ + S Y Sbjct: 433 KGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPY 467
>CP2J3_RAT (P51590) Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3)| Length = 502 Score = 66.6 bits (161), Expect = 7e-11 Identities = 45/151 (29%), Positives = 72/151 (47%), Gaps = 3/151 (1%) Frame = -1 Query: 665 ICSAYTPEWQERLRKEVLKEFGMQSPDPNALNK--LKEMTMVLFETLRLYSPALF-MQRK 495 +C A PE QE+++ E+ + G Q PN ++ + V+ E R+ + F + R+ Sbjct: 325 LCMALYPEVQEKMQAEIDRVIG-QGRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPRE 383 Query: 494 TVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLA 315 D + LPKG I+ + +HRD + W D F P F G K L Sbjct: 384 VAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATP-DTFNPEHFLEN--GQFKKRESFLP 440 Query: 314 FSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 222 FSMG R+C+G+ + E + ++QKF+F Sbjct: 441 FSMGKRACLGEQLARSELFIFITSLIQKFTF 471
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 66.2 bits (160), Expect = 9e-11 Identities = 44/154 (28%), Positives = 76/154 (49%), Gaps = 8/154 (5%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTV-----AD 483 PE Q+++RKE+ G + +++L + ++ETLRL+SP + ++ A+ Sbjct: 325 PEEQDKVRKEI----GSADLTFDQMSELPHLDACIYETLRLFSPQVAARKLVTEPFEFAN 380 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG---LLAF 312 ++ L G + IP+ +H D + + +D FKP RF G K LAF Sbjct: 381 KNGRTVHLKPGDVVTIPVKALHHDPQYY-EDPLTFKPERFLESNGGGMKSYRDRGVYLAF 439 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 GPR C G F++ + K+ L +L+ F ++P Sbjct: 440 GDGPRHCPGMRFALTQLKAALVEILRNFEIKVNP 473
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 65.5 bits (158), Expect = 1e-10 Identities = 48/156 (30%), Positives = 81/156 (51%), Gaps = 9/156 (5%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A + Q R+RKE + + + N ++ L + V+ ETLRLY+ + R+ + D Sbjct: 325 AQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLED 384 Query: 482 MTV-GSLK--LPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVPHG 324 V G K + KG+ ++IP MHRD++++ + + D F P R K + Sbjct: 385 YEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKE------RDSVE 438 Query: 323 LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 L F GPR+CIG F ++A+ LAL+++ F F++ Sbjct: 439 WLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSV 474
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/153 (28%), Positives = 79/153 (51%), Gaps = 4/153 (2%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + PE +++++KE+ + G ++P N N L + + E LR+ A + + + +DM Sbjct: 320 HNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRIRPVAPMLIPHRANSDM 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSM 306 ++G +PK ++I + +H ++ W D D F P RF + TG+ + L L F Sbjct: 380 SIGEFSIPKFTPVIINLWALHHSEKEW-DQPDRFMPERFLDP-TGSHLITPSLSYLPFGA 437 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 G RSCIG+ + E +A +LQ+F + D Sbjct: 438 GARSCIGEVLARQELFLFMAHLLQRFDLDVPDD 470
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 65.1 bits (157), Expect = 2e-10 Identities = 50/178 (28%), Positives = 78/178 (43%) Frame = -1 Query: 668 CICSAYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTV 489 C+ + +ER+R+E K Q L K+ + VL E LRL P R+ + Sbjct: 267 CLLLGQHSDIRERVRQEQNKLQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELI 326 Query: 488 ADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 D PKG + I H D +++ D ++F P RF + P + F Sbjct: 327 QDCQFQGFHFPKGWLVSYQISQTHADPDLY-PDPEKFDPERFTPDGSATHNPPFAHVPFG 385 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 G R C+G+ F+ LE K ++Q+F +TL P V + +PK L+V + L Sbjct: 386 GGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPKDNLRVKLHSL 443
>C71AM_ARATH (Q9STL1) Cytochrome P450 71A22 (EC 1.14.-.-)| Length = 490 Score = 65.1 bits (157), Expect = 2e-10 Identities = 40/159 (25%), Positives = 78/159 (49%), Gaps = 2/159 (1%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEF-GMQSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + PE RL++EV G S + + + + V+ ET+RL+ P L + ++ D+ Sbjct: 310 HRPECLNRLQEEVRTICKGNSSVSEDDIKDMNYLKAVIKETMRLHPPLPLMVPHESTQDV 369 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 +G +P G ++I + R+ WG DA++F+P R N L+ F G Sbjct: 370 RLGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPERHLNSSVDFRGHNFELIPFGAGR 429 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 183 R C +F+++ + TLA ++ ++ + L +Y+ ++ Sbjct: 430 RICPAISFAVILIEVTLANLVHRYDWRLPEEYIEDQTNV 468
>C6A23_DROME (Q9V771) Probable cytochrome P450 6a23 (EC 1.14.-.-) (CYPVIA23)| Length = 502 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/148 (29%), Positives = 77/148 (52%), Gaps = 4/148 (2%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPD--PNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSL 465 Q++LR E+ + + + ++K + V+ ETLR Y + R T D + Sbjct: 328 QDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDP 387 Query: 464 K--LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 K + KG +VIP +H D E++ + ++FKP RF + AA+ L F GPR+C Sbjct: 388 KYFIAKGTTVVIPALGIHYDPEIY-PEPEKFKPERFTDEAI-AARPSCTWLPFGEGPRNC 445 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLSPD 207 IG F +++A LA +++ + F++S + Sbjct: 446 IGLRFGLMQACVGLAYLIRGYKFSVSTE 473
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 64.7 bits (156), Expect = 3e-10 Identities = 51/178 (28%), Positives = 88/178 (49%), Gaps = 11/178 (6%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFETLRLYSPALFMQRKTVADMTV-- 474 Q+R+ E+ FG S P EM + L ETLR+Y P + R+ D+ + Sbjct: 402 QDRVLAELDSIFG-DSQRPATFQDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNS 460 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVPHGLLAFSM 306 G+ +P+G + + ++HR+ +V+ + D D F P R N + + + FS Sbjct: 461 GNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPERQAN------RHYYAFVPFSA 514 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSF--TLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 GPRSC+G+ ++ML+ K L+ +L+ + L+ DI LK + G +V ++P Sbjct: 515 GPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQADII-LKREEGFRVRLQP 571
>CP6A2_DROME (P33270) Cytochrome P450 6a2 (EC 1.14.-.-) (CYPVIA2) (P450-B1)| Length = 506 Score = 64.3 bits (155), Expect = 3e-10 Identities = 45/148 (30%), Positives = 74/148 (50%), Gaps = 5/148 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A + Q+RLR E+ Q ++ + + V+ ETLRLY+ ++RK + D Sbjct: 327 AQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALND 386 Query: 482 MTVGS---LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAF 312 V L + KG ++IP HRD++++ + + F P RF AA+ L F Sbjct: 387 YVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPERFSPEKV-AARESVEWLPF 444 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKF 228 GPR+CIG F ++A+ LA ++ +F Sbjct: 445 GDGPRNCIGMRFGQMQARIGLAQIISRF 472
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 63.9 bits (154), Expect = 4e-10 Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 7/177 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 PE Q+++ +E+ F +S L +K + V+ E+LRL+ F+ R D + Sbjct: 334 PEIQDKVYEELDHIFQGSDRSTTMRDLADMKYLERVIKESLRLFPSVPFIGRVLKEDTKI 393 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVPHGLLAFSM 306 G +P G + + I +HR+++ + + + D F P R A + P+ + FS Sbjct: 394 GDYLVPAGCMMNLQIYHVHRNQDQYPNPEAFNPDNFLPERV------AKRHPYAYVPFSA 447 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSF-TLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 GPR+CIGQ F+ LE K+ L+ +L+ F ++ ++ L+P+ G++V + P Sbjct: 448 GPRNCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMNELILRPESGIKVELIP 504
>CP17A_PERLE (Q91Z85) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 63.9 bits (154), Expect = 4e-10 Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 9/180 (5%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + PE +++++KE+ + G ++P N N L + + E LR+ A + + K D Sbjct: 318 HNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRIRPVAPMLIPHKANIDS 377 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSM 306 ++G +PK +VI + +H +++ W D D F P RF + TG+ + L L F Sbjct: 378 SIGEFTIPKDTHVVINLWALHHNEKEW-DQPDRFMPERFLDA-TGSHLITPSLSYLPFGA 435 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTL-----SPDYVHAPVDIFTLKPKFGLQVFVR 141 GPR+CIG+ + +A +LQ+F + P P +F + P F ++V VR Sbjct: 436 GPRACIGEVLARQVLFLYVACLLQRFDLDVPDGAPMPCLKGDPKVVFLIDP-FKVKVTVR 494
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 63.9 bits (154), Expect = 4e-10 Identities = 42/142 (29%), Positives = 72/142 (50%), Gaps = 2/142 (1%) Frame = -1 Query: 647 PEWQER--LRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 PE Q+R L + E ++P L++++ M M + E LRLY + RK ++ + Sbjct: 336 PECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRL 395 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 LP G + I HR ++ D ++F+P RF + P+ L FS GPR Sbjct: 396 AKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSPE-NSENRHPYAFLPFSAGPRY 453 Query: 293 CIGQNFSMLEAKSTLALMLQKF 228 CIG F+++E K+ ++ +L+ + Sbjct: 454 CIGNRFAIMEIKTIVSRLLRSY 475
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 63.9 bits (154), Expect = 4e-10 Identities = 49/157 (31%), Positives = 77/157 (49%), Gaps = 8/157 (5%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVAD-- 483 A P+ Q +LR+E+ G +++L + ETLR++SP L RK V + Sbjct: 323 ARNPKEQMKLREEI----GTAELTFEQISELPFTEACIHETLRIFSPVL-AARKVVTEPC 377 Query: 482 ----MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV-PHGLL 318 S+KL G ++IP+ +H D + + ++ FKP RF N GA K GL Sbjct: 378 ELTNKNGVSVKLRPGDVVIIPVNALHHDPQYY-EEPQSFKPERFLNINGGAKKYRDQGLF 436 Query: 317 -AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 F GPR C G FS+ + K+ L +++ F ++P Sbjct: 437 FGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNP 473
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 63.9 bits (154), Expect = 4e-10 Identities = 40/145 (27%), Positives = 66/145 (45%), Gaps = 6/145 (4%) Frame = -1 Query: 644 EWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG- 471 E QE+LR E+L+ + + +N L + E+LRL +P F R + Sbjct: 353 EEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNESLRLTTPIGFFMRICTKPTQINL 412 Query: 470 ----SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 +L L G+ +++P H D +++ +A EF+P RF+NG L F G Sbjct: 413 GDDKTLDLEPGVTVMVPAYQYHHDNDIY-PEASEFRPDRFENGAASVLTKRGCFLPFGDG 471 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKF 228 PR C+G L K+ + +L + Sbjct: 472 PRICLGMRVGQLSVKTAIVHILSNY 496
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 63.5 bits (153), Expect = 6e-10 Identities = 47/160 (29%), Positives = 80/160 (50%), Gaps = 9/160 (5%) Frame = -1 Query: 680 SHGQCICSAYTPEWQERLRKEVL---KEFGMQSPDPNALNKLKEMTMVLFETLRLYSPAL 510 +H C+ P Q+RL +E++ +E Q + L K+K + MV+ E LR + P++ Sbjct: 332 THELCL----NPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSI 387 Query: 509 FMQRKTVADMTVGS------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 348 R+ D+ + KG + IPI +H D E + +D + F P RF +G Sbjct: 388 STDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENF-EDPEFFNPERFADGHA 446 Query: 347 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 ++V + F +GPR+CIG +++E KS + +L F Sbjct: 447 LESRV---YMPFGVGPRNCIGNRMALMELKSIVYQLLLNF 483
>CP52A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA1)| (Alkane-inducible P450-ALK1) Length = 543 Score = 63.5 bits (153), Expect = 6e-10 Identities = 44/155 (28%), Positives = 74/155 (47%), Gaps = 15/155 (9%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM------QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 PE +LR+E+ +FG+ + L + + V+ ETLR+Y R Sbjct: 356 PEIFAKLREEIENKFGLGQDARVEEISFETLKSCEYLKAVINETLRIYPSVPHNFRVATR 415 Query: 485 DMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV 333 + T+ + + KG ++ I HRDK+++G+DA F+P R+ T K+ Sbjct: 416 NTTLPRGGGEGGLSPIAIKKGQVVMYTILATHRDKDIYGEDAYVFRPERWFEPET--RKL 473 Query: 332 PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 + F+ GPR C+GQ F++ EA +LQ+F Sbjct: 474 GWAYVPFNGGPRICLGQQFALTEASYVTVRLLQEF 508
>CP6G2_DROME (Q9V675) Probable cytochrome P450 6g2 (EC 1.14.-.-) (CYPVIG2)| Length = 519 Score = 63.2 bits (152), Expect = 7e-10 Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 9/156 (5%) Frame = -1 Query: 638 QERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG- 471 Q+RLR+E+ L E G Q + L+ M M+L E LR+Y P F+ R+ + Sbjct: 339 QQRLREEIKDALVESGGQVT-LKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSL 397 Query: 470 -----SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSM 306 +PKG+ + IP +H D + + +F P RF P+ + F + Sbjct: 398 APFHKKFVVPKGMPVYIPCYALHMDPQYFPQPR-KFLPERFSPE-NRKLHTPYTYMPFGL 455 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH 198 GP CIG+ F L+AK L +L+ T S H Sbjct: 456 GPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPH 491
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 62.8 bits (151), Expect = 1e-09 Identities = 47/153 (30%), Positives = 75/153 (49%), Gaps = 7/153 (4%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN----ALNKLKEMTMVLFETLRLYSPALFMQRKTV 489 A P+ Q+++R EV E ++ D N LK + VL ETLRLY+ + R Sbjct: 327 AKNPDIQDKVRAEV--EEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAA 384 Query: 488 ADMTVG---SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLL 318 V + + G +++IP +H D ++ + EF+P RF A + L Sbjct: 385 KRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPF-EFRPERFSPE-ESAGRPSVAWL 442 Query: 317 AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFT 219 F GPR+CIG F ++A+ LAL+++ F F+ Sbjct: 443 PFGDGPRNCIGLRFGQMQARIGLALLIRNFKFS 475
>CP310_DROME (Q9VJ71) Probable cytochrome P450 310a1 (EC 1.14.-.-) (CYPCCCXA1)| Length = 492 Score = 62.8 bits (151), Expect = 1e-09 Identities = 46/154 (29%), Positives = 76/154 (49%), Gaps = 9/154 (5%) Frame = -1 Query: 635 ERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLK 462 E+LR E+ KE ++ LN L+ M M L ETLR Y P ++R ++ + K Sbjct: 307 EKLRAEI-KELSNENGQLKFEELNGLRYMDMCLKETLRKYPPLPIIERVCRKSYSLPNSK 365 Query: 461 --LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVP-----HGLLAFSMG 303 + +G +++P+ MHRD++ + + ++KPLRF + + + F +G Sbjct: 366 FTIDEGKTLMVPLLAMHRDEKYFSEPM-KYKPLRFLQTANDVGQCEDKTKSNVFIGFGIG 424 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYV 201 C+GQNF+ L K L +LQ F L + V Sbjct: 425 GSQCVGQNFAKLVIKVALIKLLQNFHLELDANQV 458
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 62.8 bits (151), Expect = 1e-09 Identities = 51/176 (28%), Positives = 80/176 (45%), Gaps = 29/176 (16%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLY-SPALFMQRKTVADM 480 A P ++ + EV G P +L +L+ + +++ E LRLY P L ++R +D+ Sbjct: 370 AQNPSKMKKAQAEVDLVLGTGRPTFESLKELQYIRLIVVEALRLYPQPPLLIRRSLKSDV 429 Query: 479 TVGSLK-------LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----KN----GITG 345 G K +P G + I + +HR W D D+F+P RF KN G G Sbjct: 430 LPGGHKGEKDGYAIPAGTDVFISVYNLHRSPYFW-DRPDDFEPERFLVQNKNEEIEGWAG 488 Query: 344 A--AKVPHGL-----------LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 ++ P L L F GPR C+G F+++E+ L ++LQ F L Sbjct: 489 LDPSRSPGALYPNEVISDFAFLPFGGGPRKCVGDQFALMESTVALTMLLQNFDVEL 544
>CP52L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane hydroxylase| 1) (Alkane-inducible p450alk 1) (DH-ALK2) Length = 519 Score = 62.8 bits (151), Expect = 1e-09 Identities = 47/170 (27%), Positives = 81/170 (47%), Gaps = 15/170 (8%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFG------MQSPDPNALNKLKEMTMVLFETLRLYS--PALFMQ 501 A P+ +L++E+ ++FG ++ +L K + + +L E LRLY P F Sbjct: 333 ARNPQVWLKLKEEIYEKFGKGDDARLEDITFESLKKCEYLKALLNEVLRLYPSVPQNFRV 392 Query: 500 RKTVADMTVGS-------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 342 + + G + + KG + + MHRD++ +G D++ F+P R+ T Sbjct: 393 AQKDTSLPRGGGPNRDQPIFIAKGQTVTYTVYAMHRDEQFYGKDSEVFRPERWFEPET-- 450 Query: 341 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAP 192 K+ L F+ GPR C+GQ F++ EA +A + Q F S D + P Sbjct: 451 RKLGWAFLPFNGGPRICLGQQFALTEASYVIARLAQLFPNLASHDDEYPP 500
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 2/119 (1%) Frame = -1 Query: 578 ALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEV 402 ++ +K + MV+ ETLR Y F+ R+ D + L LP G + IP+ +H D + Sbjct: 350 SIKDMKYLDMVVNETLRKYPAIPFLDRRCQEDYPLTQDLMLPAGTGVYIPVYALHHDSKY 409 Query: 401 WGDDADEFKPLRFKNGITGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 + A +F P RF +PH + F GPR+CIG F ++ K+ L +L F Sbjct: 410 FPSPA-KFDPERFSE--KNKQNIPHFAYMPFGEGPRNCIGMRFGSMQVKAALIHILSNF 465
>CP17A_CAVPO (Q64410) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 62.4 bits (150), Expect = 1e-09 Identities = 46/180 (25%), Positives = 86/180 (47%), Gaps = 8/180 (4%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ ++++++E+ G ++P + N L + + E LR+ A + + K D Sbjct: 320 HNPQVKKKIQEEIDHNVGFSRTPTFSDRNHLLMLEATIREVLRIRPVAPILIPHKANTDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG-LLAFSMG 303 ++G + K +++ + +H +++ W D D+F P RF + VP L F G Sbjct: 380 SIGEFAIDKDTNVLVNLWALHHNEQEW-DRPDQFMPERFLDPTGSQIIVPSSSYLPFGAG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLS-----PDYVHAPVDIFTLKPKFGLQVFVRP 138 PRSC+G+ + E A +LQKF + P P +F + P F +++ VRP Sbjct: 439 PRSCVGEALARQEIFLITAWLLQKFDLEVPEGGQLPSLEGIPKIVFLIDP-FKVKITVRP 497
>CP313_DROME (Q9VHP4) Probable cytochrome P450 313b1 (EC 1.14.-.-)| (CYPCCCXIIIB1) Length = 502 Score = 62.4 bits (150), Expect = 1e-09 Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 6/152 (3%) Frame = -1 Query: 665 ICSAYTPEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETLRLYSPALFMQRKT 492 +C A P +QE+L KE++ E S D N L +L+ MV+ E +RL++P + R Sbjct: 321 LCLAMHPCYQEKLHKELVTELP-PSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSA 379 Query: 491 VADMTV----GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG 324 D+ + G +P+G I I I M RD+ VWG + + P G+ + Sbjct: 380 DQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNP-DAHFGLDSPQRHAFA 438 Query: 323 LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 + F+ G R CIG ++ + K LA + + + Sbjct: 439 FVPFTKGLRMCIGYRYAQMLMKLLLARIFRSY 470
>CP2J2_HUMAN (P51589) Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic| acid epoxygenase) Length = 502 Score = 62.4 bits (150), Expect = 1e-09 Identities = 43/147 (29%), Positives = 67/147 (45%), Gaps = 2/147 (1%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVAD 483 A PE QE+++ E+ + G Q P A + V+ E R+ + L + R+ D Sbjct: 328 ALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVD 387 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 T+ LPKG I+ + +HRD W D F P F G K + FS+G Sbjct: 388 TTLAGYHLPKGTMILTNLTALHRDPTEWATP-DTFNPDHFLEN--GQFKKREAFMPFSIG 444 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 R+C+G+ + E ++QKF+F Sbjct: 445 KRACLGEQLARTELFIFFTSLMQKFTF 471
>CP392_DROME (P82713) Probable cytochrome P450 309a2 (EC 1.14.-.-) (CYPCCCIXA2)| Length = 538 Score = 62.0 bits (149), Expect = 2e-09 Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 8/158 (5%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A P Q++LR E+L + S D L+ L+ + V++E+LRL S L Q V + Sbjct: 357 AENPAVQQKLRVEILSCMASEKSLDFEKLSSLQYLEQVIYESLRLSS--LIPQYTKVCTL 414 Query: 479 TV-------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL 321 SL + G+ I+IP H DK+ + + + FKP RF NG Sbjct: 415 PTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYF-PEPEAFKPERFDNGAYQELMRKGIF 473 Query: 320 LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 L FS GPR C+G +ML KS L +L F D Sbjct: 474 LPFSDGPRICMGVPLAMLTLKSALVHILSNFQVVRGRD 511
>CP53_ASPNG (P17549) Benzoate 4-monooxygenase (EC 1.14.13.12)| (Benzoate-para-hydroxylase) (Cytochrome P450 53) (BpH) Length = 517 Score = 62.0 bits (149), Expect = 2e-09 Identities = 48/174 (27%), Positives = 84/174 (48%), Gaps = 7/174 (4%) Frame = -1 Query: 650 TPEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETLRLYSP-ALFMQRKTVAD- 483 TP E+L K + + + P + + + V++ET+R++S A+ + R+ A Sbjct: 337 TPGVIEKLHKALDEAIPQDVDVPTHAMVKDIPYLQWVIWETMRIHSTSAMGLPREIPAGN 396 Query: 482 --MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG-ITGAAKVPHGLLAF 312 +T+ G + +P +HR KE+WG DA++F P R+ +T K + F Sbjct: 397 PPVTISGHTFYPGDVVSVPSYTIHRSKEIWGPDAEQFVPERWDPARLTPRQKA--AFIPF 454 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQV 150 S GPR+C+G+N + +E + + F F + + + F KP GLQV Sbjct: 455 STGPRACVGRNVAEMELLVICGTVFRLFEFEMQQEGPMETREGFLRKP-LGLQV 507
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 62.0 bits (149), Expect = 2e-09 Identities = 35/120 (29%), Positives = 65/120 (54%), Gaps = 6/120 (5%) Frame = -1 Query: 569 KLKEMTMVLFETLRLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWG 396 ++K + V+ ETLRLY P + R+ D+ + G +PKG +++ +HR +++ Sbjct: 405 EMKYLERVILETLRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYP 464 Query: 395 D----DADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 + D D F P R N + + + FS GPRSC+G+ ++ML+ K L+ +++ + Sbjct: 465 NPTKFDPDNFLPERMAN------RHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNY 518
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 62.0 bits (149), Expect = 2e-09 Identities = 40/119 (33%), Positives = 68/119 (57%), Gaps = 3/119 (2%) Frame = -1 Query: 575 LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVW 399 L+KL + + ET+RLY M R+T+ + + L LPK I I + +HR+ + W Sbjct: 371 LSKLNYLGYFIKETMRLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYW 430 Query: 398 GDDADEFKPLRF--KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 + +EF+P RF +N + + P+ + FS G R+CIGQ ++M E K+ + ++L+ F Sbjct: 431 -ESPEEFRPERFLPQNCLK---RHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHF 485
>CP2J1_RABIT (P52786) Cytochrome P450 2J1 (EC 1.14.14.1) (CYPIIJ1) (P-450IB)| Length = 500 Score = 62.0 bits (149), Expect = 2e-09 Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 2/147 (1%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVAD 483 A PE QE++ E+ G Q P + L V+ E R+ + L + R+ D Sbjct: 326 ALYPEIQEKVHAEIDSVIGQWQQPSMASRESLPYTNAVIHEVQRMGNILPLNVPREVTVD 385 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 T+ LPKG ++ + +H+D E W D F P F G K + FS+G Sbjct: 386 TTLAGYHLPKGTVVLTNLTALHKDPEEWA-TPDTFNPEHFLE--NGQFKKKEAFIPFSIG 442 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 R+C+G+ + E ++QKF+F Sbjct: 443 KRACLGEQLAKSELFIFFTSLMQKFTF 469
>C71AO_ARATH (Q9STK9) Cytochrome P450 71A24 (EC 1.14.-.-)| Length = 486 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/153 (26%), Positives = 72/153 (47%), Gaps = 1/153 (0%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTVGSLK 462 QE +R + G+ D L +K + V+ ETLRL+ P L + ++ D+ + Sbjct: 318 QEEVRMVCKDKSGVSEDD---LQDMKYLKAVIKETLRLHPPLPLMVPHESTHDVKLRDYH 374 Query: 461 LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQ 282 +P G ++I + R+ WG DA+EF+P R N L+ F G R C Sbjct: 375 IPAGTHVMINAWAIGREAATWGPDAEEFRPERHLNSYVDYRGQDTELVPFGAGRRICPAI 434 Query: 281 NFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 183 +F+++ + LA ++ +F +TL + D+ Sbjct: 435 SFAVVLDEVVLANLVHQFDWTLPEESTEYQTDV 467
>CP9B2_DROME (Q9V4I1) Cytochrome P450 9b2 (EC 1.14.-.-) (CYPIXB2)| Length = 505 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/157 (29%), Positives = 75/157 (47%), Gaps = 9/157 (5%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 Y P+ QERL +E+++ + P +A+ K+ M MV+ E+LR ++ A R D Sbjct: 322 YNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKD 381 Query: 482 MTVGS------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL 321 T+ G I IPI +H D + + +F P RF G VP+ Sbjct: 382 YTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPR-KFDPDRFSEERKGDM-VPYTY 439 Query: 320 LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 L F +GPR+CIG +++++ K L +L + SP Sbjct: 440 LPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASP 476
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/152 (27%), Positives = 75/152 (49%), Gaps = 3/152 (1%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ +++L +E+ + G ++P + N+L + + E LRL A + + K D Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPH-GLLAFSMG 303 ++G + KG ++I + +H +++ W D+F P RF N P L F G Sbjct: 380 SIGEFAVDKGTQVIINLWALHHNEKEW-HQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 PRSCIG+ + E +A +LQ+F + D Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 61.6 bits (148), Expect = 2e-09 Identities = 42/152 (27%), Positives = 75/152 (49%), Gaps = 3/152 (1%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ +++L +E+ + G ++P + N+L + + E LRL A + + K D Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPH-GLLAFSMG 303 ++G + KG ++I + +H +++ W D+F P RF N P L F G Sbjct: 380 SIGEFAVDKGTEVIINLWALHHNEKEW-HQPDQFMPERFLNPAGTQLISPSVSYLPFGAG 438 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 PRSCIG+ + E +A +LQ+F + D Sbjct: 439 PRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>C11B1_PIG (Q29552) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 1/144 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN-ALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE Q+ LR+E L S +P A+ +L + L ETLRLY +F+ R +D+ Sbjct: 331 ARNPEVQQALRQESLAAAARISENPQKAITELPLLRAALKETLRLYPVGIFLDRCVTSDL 390 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +P G + + + + R+ V+ + + P R+ + + PH LAF G Sbjct: 391 VLQNYHIPAGTLVKVLLYSLGRNPAVFA-RPERYHPQRWLDNQGSGTRFPH--LAFGFGM 447 Query: 299 RSCIGQNFSMLEAKSTLALMLQKF 228 R C+G+ + +E L +L+ F Sbjct: 448 RQCLGRRLAQVEMLLLLHHVLKNF 471
>CP137_MYCTU (O69653) Putative cytochrome P450 137 (EC 1.14.-.-)| Length = 476 Score = 61.6 bits (148), Expect = 2e-09 Identities = 45/140 (32%), Positives = 68/140 (48%), Gaps = 1/140 (0%) Frame = -1 Query: 554 TMVLFETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFK 375 T V+ ETLR+ PA R +T+G ++ G IV+ I ++R EV+ + EF+ Sbjct: 340 TAVINETLRVRPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVY-EHPHEFR 398 Query: 374 PLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHA 195 P RF G + + F G + C+G NFSM E + L ++L++ FT D Sbjct: 399 PERF----LGTRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPER 454 Query: 194 PV-DIFTLKPKFGLQVFVRP 138 V L P+ G +V RP Sbjct: 455 IVRRSIMLVPRRGTRVRFRP 474
>C86A1_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)| (P450-dependent fatty acid omega-hydroxylase) Length = 513 Score = 61.6 bits (148), Expect = 2e-09 Identities = 44/150 (29%), Positives = 76/150 (50%), Gaps = 5/150 (3%) Frame = -1 Query: 572 NKLKEMTMVLFETLRLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVW 399 ++L + L ETLRLY P++ K V D V +P+G + I + R K +W Sbjct: 359 DRLVYLKAALAETLRLY-PSVPQDFKYVVDDDVLPDGTFVPRGSTVTYSIYSIGRMKTIW 417 Query: 398 GDDADEFKPLRFKNGITGAAKVP---HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 G+D EF+P R+ + P + +AF+ GPR+C+G++ + + KS + +L ++ Sbjct: 418 GEDCLEFRPERWLTADGERFETPKDGYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLLRY 477 Query: 227 SFTLSPDYVHAPVDIFTLKPKFGLQVFVRP 138 P + TL K GL+V+++P Sbjct: 478 RVFPVPGHRVEQKMSLTLFMKNGLRVYLQP 507
>CP1A1_RAT (P00185) Cytochrome P450 1A1 (EC 1.14.14.1) (CYP1A1) (CYPIA1)| (P450-C) (P450MT2) [Contains: Cytochrome P450MT2A; Cytochrome P450MT2B] Length = 524 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/149 (28%), Positives = 74/149 (49%), Gaps = 3/149 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 P Q ++++E+ G + P + +L + + ET R S F + T+ D ++ Sbjct: 341 PRIQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTIRDTSL 400 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAK-VPHGLLAFSMGPR 297 +PKG + + ++ D+E+WGD +EF+P RF K + ++ F +G R Sbjct: 401 NGFYIPKGHCVFVNQWQVNHDQELWGDP-NEFRPERFLTSSGTLDKHLSEKVILFGLGKR 459 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 CIG+ LE LA++LQ+ F +SP Sbjct: 460 KCIGETIGRLEVFLFLAILLQQMEFNVSP 488
>CP1A2_BALAC (Q3LFT9) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 61.2 bits (147), Expect = 3e-09 Identities = 49/176 (27%), Positives = 87/176 (49%), Gaps = 4/176 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 PE Q ++++E+ G + P + ++L + + ET R S F + T+ D T+ Sbjct: 336 PEIQRKIQQELDTVIGRARRPRLSDRSQLPYLEAFILETFRHSSFVPFTIPHSTIRDTTL 395 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KNGITGAAKVPHGLLAFSMGP 300 +PK + + I ++ D ++WGD + EF+P RF + T + + ++ F MG Sbjct: 396 NGFYIPKELCVFINQWQVNHDPKLWGDPS-EFRPERFLTSHDTTISKTLSEKVMLFGMGK 454 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPLD 132 R CIG+ + E LA++LQ+ F++ P VD L P +GL + P + Sbjct: 455 RRCIGEVLAKWEIFLFLAILLQQLEFSVPPG---VKVD---LTPTYGLTMKPAPCE 504
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 61.2 bits (147), Expect = 3e-09 Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 4/145 (2%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A PE Q+RLR E+ + + K+ + MV+ E LR Y P F+ R + D Sbjct: 315 ALHPEIQDRLRTEIQEVTACHGGQVTYEGVKKMSYLDMVVSEVLRKYPPMSFIDRVCLHD 374 Query: 482 MTVGS--LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 + + + KG I + + +HRD ++ D ++F P RF N + P + F Sbjct: 375 YHIPGTDVVIEKGTPIFVSLLGLHRDS-IFYPDPEDFNPERF-NKEKKSGVHPFSYIPFG 432 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQ 234 GPR+CIG ++ K + ++LQ Sbjct: 433 DGPRNCIGLRLGLMSVKLVIIMLLQ 457
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 59.3 bits (142), Expect(2) = 3e-09 Identities = 38/143 (26%), Positives = 71/143 (49%), Gaps = 3/143 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM---QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 P+ Q +L +E + G +S + K+K + + + E R+Y F+ R D Sbjct: 327 PDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYD 386 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + +PKG + + + ++ + ++ D F+P RF+ P L FS GPR Sbjct: 387 INGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEE----EKPAPFEYLPFSAGPR 441 Query: 296 SCIGQNFSMLEAKSTLALMLQKF 228 +CIGQ F++LE K+ ++ +++ F Sbjct: 442 NCIGQKFALLELKTVISKVVRSF 464 Score = 21.6 bits (44), Expect(2) = 3e-09 Identities = 9/17 (52%), Positives = 14/17 (82%) Frame = -3 Query: 681 LTWSVYLLSIYPRMARK 631 +++SVYLLS +P + RK Sbjct: 316 VSFSVYLLSRHPDVQRK 332
>CP301_DROME (Q9V6D6) Probable cytochrome P450 301a1, mitochondrial precursor| (EC 1.14.-.-) (CYPCCCIA1) Length = 553 Score = 60.8 bits (146), Expect = 4e-09 Identities = 43/156 (27%), Positives = 76/156 (48%), Gaps = 9/156 (5%) Frame = -1 Query: 626 RKEVLKEFGMQSPDPNA------LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSL 465 +++V +E PDPN L+++ + + E R+YS + R + D + Sbjct: 383 QQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLMEDSVICGY 442 Query: 464 KLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF---KNGITGAAKVPHGLLAFSMGPRS 294 ++PKG+ V P I+ + E + DA F+P R+ ++G T P L + G R Sbjct: 443 QVPKGVQAVFP-TIVTGNMEEYVTDAATFRPERWLKPQHGGTPGKLHPFASLPYGYGARM 501 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVD 186 C+G+ F+ LE + LA +L+ + +Y H P+D Sbjct: 502 CLGRRFADLEMQILLAKLLRNYKL----EYNHKPLD 533
>C82A1_PEA (Q43068) Cytochrome P450 82A1 (EC 1.14.-.-) (CYPLXXXII) (Fragment)| Length = 544 Score = 60.8 bits (146), Expect = 4e-09 Identities = 54/176 (30%), Positives = 79/176 (44%), Gaps = 6/176 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLRLYSPALFMQ-RKTVADMTV 474 P E+L++E+ G + + + +NKL + ++ ETLRLY PA F R+ D T+ Sbjct: 360 PHVLEKLKEELNTYIGKERCVNESDINKLVYLHAIIKETLRLYPPAPFSSPREFTEDCTI 419 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KNGITGAAKVPHGLLAFSMGP 300 G + KG ++ + +HRD VW D EFKP RF + LL F G Sbjct: 420 GGYHIKKGTRLMPNLWKIHRDPSVWPDPL-EFKPERFLSTHKDVDVRGQNFELLPFGSGR 478 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFS-FTLSPDYVH-APVDIFTLKPKFGLQVFVRP 138 R C G + + LA L F SP+ + V F L+V V+P Sbjct: 479 RMCAGMSLGLHMVHYILANFLHSFEILNPSPESIDVTEVLEFVTTKATPLEVLVKP 534
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 60.8 bits (146), Expect = 4e-09 Identities = 42/153 (27%), Positives = 77/153 (50%), Gaps = 4/153 (2%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ +++L +E+ + G ++P + N+L + + E LR+ A + + K D Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSM 306 ++G + KG ++I + +H +++ W D+F P RF N G + L L F Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP-AGTQLISPSLSYLPFGA 437 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 GPRSCIG+ + E +A +LQ+F + D Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 60.8 bits (146), Expect = 4e-09 Identities = 42/153 (27%), Positives = 77/153 (50%), Gaps = 4/153 (2%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ +++L +E+ + G ++P + N+L + + E LR+ A + + K D Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSM 306 ++G + KG ++I + +H +++ W D+F P RF N G + L L F Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP-AGTQLISPSLSYLPFGA 437 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 GPRSCIG+ + E +A +LQ+F + D Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 60.8 bits (146), Expect = 4e-09 Identities = 42/153 (27%), Positives = 77/153 (50%), Gaps = 4/153 (2%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ +++L +E+ + G ++P + N+L + + E LR+ A + + K D Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSM 306 ++G + KG ++I + +H +++ W D+F P RF N G + L L F Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP-AGTQLISPSLSYLPFGA 437 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 GPRSCIG+ + E +A +LQ+F + D Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 60.8 bits (146), Expect = 4e-09 Identities = 41/144 (28%), Positives = 72/144 (50%), Gaps = 4/144 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 P+ QE+L E G +A ++ +K + + + E RLY F+ R T D Sbjct: 327 PDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLYPSVPFIGRFTEKDY 386 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + +PKG + + + ++ + V+ D +F+P RF G P + FS GP Sbjct: 387 VIDGDIVPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERFDREKPG----PFEYVPFSAGP 441 Query: 299 RSCIGQNFSMLEAKSTLALMLQKF 228 R+CIGQ F++LE K+ ++ +++ F Sbjct: 442 RNCIGQKFALLEIKTVVSKIIRNF 465
>CCD1P_DROME (P82712) Probable cytochrome P450 12d1 proximal, mitochondrial| precursor (EC 1.14.-.-) (CYPXIID1) Length = 521 Score = 60.8 bits (146), Expect = 4e-09 Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 6/172 (3%) Frame = -1 Query: 665 ICSAYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTM---VLFETLRLYSPALFMQRK 495 +C + P+ Q +LR+E+L + N N +K+M V+ ETLR Y L R Sbjct: 339 LCLSKHPDKQAKLREELLSIMPTKDSLLNEEN-MKDMPYLRAVIKETLRYYPNGLGTMRT 397 Query: 494 TVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV---PHG 324 D+ + ++PKG +++ ++ ++ + DEF P R+ K+ P Sbjct: 398 CQNDVILSGYRVPKGTTVLLGSNVLMKEATYY-PRPDEFLPERWLRDPETGKKMQVSPFT 456 Query: 323 LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKP 168 L F GPR CIG+ LE ++T+A +++ F + D +F ++P Sbjct: 457 FLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFVMEP 508
>CP17A_SHEEP (Q29497) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 60.5 bits (145), Expect = 5e-09 Identities = 40/151 (26%), Positives = 77/151 (50%), Gaps = 4/151 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P ++R++ + + G ++P + N+L + + E LR+ A + + K + D ++ Sbjct: 322 PSLKKRIQDSIDQNIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPMLIPHKAIIDSSI 381 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSMGP 300 G L + KG +V+ + +H +++ W D F P RF + TG + L L F GP Sbjct: 382 GDLTIDKGTDVVVNLWALHHNEKEW-QQPDLFMPERFLDP-TGTQLISPSLSYLPFGAGP 439 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 RSC+G+ + E ++ +LQ+F+ + D Sbjct: 440 RSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 60.5 bits (145), Expect = 5e-09 Identities = 42/143 (29%), Positives = 73/143 (51%) Frame = -1 Query: 566 LKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDA 387 L ++ V+ E+LRLY P + R D+ + +P G +V+ + + RD+ ++ D Sbjct: 354 LPYLSCVVKESLRLYPPIPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTDPL 413 Query: 386 DEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 F+P R G P+ + FS GPR+CIGQ F++LE K+ + +++ + Sbjct: 414 -VFQPERHL-GEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGA 471 Query: 206 YVHAPVDIFTLKPKFGLQVFVRP 138 V + I L+ K G+ V +RP Sbjct: 472 DVEPSIKI-VLRSKSGVNVGLRP 493
>C82A3_SOYBN (O49858) Cytochrome P450 82A3 (EC 1.14.-.-) (P450 CP6)| Length = 527 Score = 60.5 bits (145), Expect = 5e-09 Identities = 51/159 (32%), Positives = 72/159 (45%), Gaps = 8/159 (5%) Frame = -1 Query: 575 LNKLKEMTMVLFETLRLYSPALFMQ-RKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVW 399 ++KL + ++ ETLRLY PA F R+ + +G + KG ++ + +HRD VW Sbjct: 368 ISKLVYLQAIVKETLRLYPPAPFSSPREFTENCILGGYHIKKGTRLIHNLWKIHRDPSVW 427 Query: 398 GDDADEFKPLRFKNGITGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 225 D EFKP RF H LL F G R C G + + TLA +L F Sbjct: 428 SDPL-EFKPERFLTTHKDVDLRGHNFELLPFGSGRRVCAGMSLGLNMVHFTLANLLHSFD 486 Query: 224 FTLSPDYVHAPVDI-----FTLKPKFGLQVFVRPLDKCN 123 L+P PVD+ FT L++ V+P N Sbjct: 487 I-LNPS--AEPVDMTEFFGFTNTKATPLEILVKPRQSPN 522
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 60.5 bits (145), Expect = 5e-09 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 3/143 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQ---SPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT 477 PE Q +L +E G + ++ +K + + + E R+Y F+ R T D Sbjct: 327 PEEQRKLYEEQQAVMGNELNRDATFQEISAMKYLDLFIKEAQRVYPSVPFIGRYTDKDYN 386 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + +PKG + + I ++ D V+ ++ F P RF+ G P + FS GPR Sbjct: 387 IHGTIMPKGTTLNLGIIVLGYDDRVF-EEPHRFYPERFEKQKPG----PFEYVPFSAGPR 441 Query: 296 SCIGQNFSMLEAKSTLALMLQKF 228 +CIGQ F++LE K+ ++ +++ F Sbjct: 442 NCIGQKFALLELKTVISKLVRTF 464
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 60.5 bits (145), Expect = 5e-09 Identities = 49/153 (32%), Positives = 75/153 (49%), Gaps = 5/153 (3%) Frame = -1 Query: 575 LNKLKEMTMVLFETLRLYSPALFMQRKTVA--DMTVGSLKLPKGIAIVIPIPIMHRDKEV 402 +++L + L ETLRLY P++ K V D+ +P G ++ I R K Sbjct: 362 VDRLVYLKAALSETLRLY-PSVPEDSKHVVNDDILPDGTFVPAGSSVTYSIYAAGRMKST 420 Query: 401 WGDDADEFKPLRFKNGITGAAKVPHG---LLAFSMGPRSCIGQNFSMLEAKSTLALMLQK 231 WG+D EFKP R+ + G V H +AF+ GPR C+G++ + L+ K+ A +L + Sbjct: 421 WGEDCLEFKPERWISPDDGKF-VNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLR 479 Query: 230 FSFTLSPDYVHAPVDIFTLKPKFGLQVFVRPLD 132 T++P + TL K GL V V D Sbjct: 480 HRLTVAPGHKVEQKMSLTLFMKNGLLVNVHKRD 512
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 60.5 bits (145), Expect = 5e-09 Identities = 46/177 (25%), Positives = 86/177 (48%), Gaps = 8/177 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P+ ++L++E+ + G ++P + N+L + + E LR+ A + K + D ++ Sbjct: 322 PQLYKKLQEEIDQNIGFSRTPTMSDRNQLILLEATIREVLRIRPVAPTLIPHKAIMDSSI 381 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPH-GLLAFSMGPR 297 G + KG ++I + +H +++ W D+F P RF + P L F GPR Sbjct: 382 GEFAVDKGTNVIINLWALHHNEKEWYRP-DQFMPERFLDPTRSQLISPSLSYLPFGAGPR 440 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLS-----PDYVHAPVDIFTLKPKFGLQVFVR 141 SC+G++ + E +A +LQ+F + P P +F + P F ++V VR Sbjct: 441 SCLGESLARQEVFLFMAWLLQRFDLEVPDDGQLPHLEGNPTVVFLIAP-FKVKVKVR 496
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 60.1 bits (144), Expect = 6e-09 Identities = 40/117 (34%), Positives = 62/117 (52%), Gaps = 2/117 (1%) Frame = -1 Query: 572 NKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGD 393 N+L + V+ E+LRL+ A + R + + + L LPK I I I + RD + Sbjct: 363 NELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHF-P 421 Query: 392 DADEFKPLRF--KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 ++F P RF +N + + P + FS GPR+CIGQ F +LE K LA +++ F Sbjct: 422 KPNQFLPERFLPENSVN---RHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNF 475
>CP52H_CANTR (P30610) Cytochrome P450 52A8 (EC 1.14.14.-) (CYPLIIA8)| (Alkane-inducible P450-ALK5) Length = 517 Score = 60.1 bits (144), Expect = 6e-09 Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 16/171 (9%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVLFETLRLYSPALFMQRK 495 A P +LR++V +FG+ +L + + L ETLR+Y R Sbjct: 330 ARNPHIWAKLREDVESQFGLGEQSRIEEITFESLKRCGYLKAFLNETLRVYPSVPRNFRI 389 Query: 494 TVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 342 + T+ + + KG A+ I H D +GDDA EF+P R+ T Sbjct: 390 ATKNTTLPRGGGSDGNSPVLVKKGEAVSYGINSTHLDPVYYGDDAAEFRPERWNEPST-- 447 Query: 341 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTLSPDYVHAP 192 K+ L F+ GPR C+GQ F++ EA L + Q F + L P V+ P Sbjct: 448 RKLGWAYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFDTLELKPPVVYPP 498
>C81D1_ARATH (Q9FG65) Cytochrome P450 81D1 (EC 1.14.-.-)| Length = 502 Score = 60.1 bits (144), Expect = 6e-09 Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 2/144 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA-LNKLKEMTMVLFETLRLY-SPALFMQRKTVADMTV 474 P+ + R E+ G+ A L++L + ++ ETLRL+ + L + D + Sbjct: 326 PDVISKARDEIDNRVGLDRLIEEADLSELPYLKNIVLETLRLHPATPLLVPHMASEDCKI 385 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 GS +P+G +++ +HRD W DD D FKP RF+ + LLAF +G R+ Sbjct: 386 GSYDMPRGTTLLVNAWAIHRDPNTW-DDPDSFKPERFEK-----EEEAQKLLAFGLGRRA 439 Query: 293 CIGQNFSMLEAKSTLALMLQKFSF 222 C G + L ++Q F + Sbjct: 440 CPGSGLAQRIVGLALGSLIQCFEW 463
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 60.1 bits (144), Expect = 6e-09 Identities = 42/146 (28%), Positives = 71/146 (48%), Gaps = 2/146 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEF-GMQSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 PE ++L+ EV + + + + K+ + V+ ET+R ++P L + R D+ V Sbjct: 328 PEIMKKLQSEVRQVVKDKHNITDDDIEKMHYLKAVMKETMRFHTPIPLLVPRVARNDVEV 387 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 +P G ++I + RD W D+ ++F+P RF N + L+ F G R Sbjct: 388 MGYDVPVGTMVMINAWAIGRDPTSW-DEPEKFRPERFLNSSVDFKGLDFELIPFGAGRRG 446 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTL 216 C G F M + TLA ++QKF + L Sbjct: 447 CPGTTFPMATLEFTLANLMQKFDWEL 472
>CP52N_CANTR (P30611) Cytochrome P450 52B1 (EC 1.14.14.-) (CYPLIIB1)| (Alkane-inducible P450-ALK6) Length = 506 Score = 59.7 bits (143), Expect = 8e-09 Identities = 52/166 (31%), Positives = 81/166 (48%), Gaps = 19/166 (11%) Frame = -1 Query: 632 RLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLK 462 +LR+E+ FG++SPD ++L K K + +L ETLR+Y P + KT T Sbjct: 327 KLREEIDANFGLESPDLLTFDSLRKFKYVQAILNETLRMY-PGVPRNMKTAKCTTT---- 381 Query: 461 LPKGIAIVIPIPIM--------------HRDKEV-WGDDADEFKPLRFKNGITGAAKVPH 327 LPKG PI+ H D + +G DA F+P R+ + + + Sbjct: 382 LPKGGGPDGQDPILVKKGQSVGFISIATHLDPVLNFGSDAHVFRPDRWFD--SSMKNLGC 439 Query: 326 GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS-PDYVHAP 192 L F+ GPR+C+GQ ++++EA L + Q + S PD V+ P Sbjct: 440 KYLPFNAGPRTCLGQQYTLIEASYLLVRLAQTYETVESHPDSVYPP 485
>CP17A_CHICK (P12394) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 59.7 bits (143), Expect = 8e-09 Identities = 49/173 (28%), Positives = 89/173 (51%), Gaps = 4/173 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRL--YSPALFMQRKTVADMT 477 PE Q+++++E+ ++ G+ + P + L + + E LR+ SP L + ++AD + Sbjct: 325 PEVQKKIQEEMDQKIGLARHPHLSDRPLLPYLEATISEGLRIRPVSP-LLIPHVSLADTS 383 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPH-GLLAFSMGP 300 +G +PKG +VI + +H D++ W D +EF P RF + P L F G Sbjct: 384 IGEYSIPKGARVVINLWSVHHDEKEW-DKPEEFNPGRFLDEQGQHIHSPSPSYLPFGAGI 442 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGLQVFVR 141 R C+G+ + +E LA +LQ+F+ D + +L+ KFG+ + V+ Sbjct: 443 RVCLGEVLAKMELFLFLAWVLQRFTLECPQDQ-----PLPSLEGKFGVVLQVQ 490
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 59.7 bits (143), Expect = 8e-09 Identities = 51/176 (28%), Positives = 80/176 (45%), Gaps = 7/176 (3%) Frame = -1 Query: 656 AYTPEWQERLRKEV----LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTV 489 A PE +RL+ EV K G + D +LNK++ + + + ET+R Y + R+ Sbjct: 335 AQYPELLKRLQDEVDETLAKNDGKITYD--SLNKMEFLDLCVQETIRKYPGLPILNRECT 392 Query: 488 ADMTVGSLK--LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLA 315 D TV +PKG +VI + +H D E + D + + P RF P + Sbjct: 393 QDYTVPDTNHVIPKGTPVVISLYGIHHDAEYF-PDPETYDPERFSEESRNYN--PTAFMP 449 Query: 314 FSMGPRSCIGQNFSMLEAKSTLALMLQKFSF-TLSPDYVHAPVDIFTLKPKFGLQV 150 F GPR CI Q + +K + +LQ F+ +S + L PK G++V Sbjct: 450 FGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIALIPKHGVRV 505
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/141 (27%), Positives = 75/141 (53%), Gaps = 4/141 (2%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 Q +L KE + G +A ++++K + + + E R+Y F+ R T D + Sbjct: 330 QRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVID 389 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 +PKG + + + ++ +++V+ D +F+P RF+ G P + FS GPR+C Sbjct: 390 GDLVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERFELEKPG----PFEYVPFSAGPRNC 444 Query: 290 IGQNFSMLEAKSTLALMLQKF 228 IGQ F++LE K+ ++ +++ F Sbjct: 445 IGQKFALLEIKTVVSKIIRNF 465
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 59.3 bits (142), Expect = 1e-08 Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 4/150 (2%) Frame = -1 Query: 647 PEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 PE ++L+ E+ ++ G + N ++ + V+ E R++ P L + R D+ Sbjct: 318 PECMKKLQNEIRSTIRPHGSYIKEKEVEN-MRYLKAVIKEVFRVHPPLPLILPRLLTEDV 376 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 V + G ++I +HRD +WG DA+EFKP R + + F G Sbjct: 377 KVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHLDSTLDYHGQDLKYIPFGSGR 436 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 R C G N +M + TLA ++ +F +++ P Sbjct: 437 RICPGINLAMGLVEVTLANLVGRFDWSVDP 466
>C6A18_DROME (Q9VB31) Probable cytochrome P450 6a18 (EC 1.14.-.-) (CYPVIA18)| Length = 507 Score = 59.3 bits (142), Expect = 1e-08 Identities = 54/184 (29%), Positives = 90/184 (48%), Gaps = 10/184 (5%) Frame = -1 Query: 656 AYTPEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A P Q+++R E+ + E Q + LK + V+ ETLR Y+ + R Sbjct: 327 AKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKR 386 Query: 482 MTV-GSLK--LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPH-GLLA 315 V G+ K + G +++IP +H D ++ + +EF+P RF +AK P L Sbjct: 387 FVVPGNPKFVIEAGQSVIIPSSAIHHDPSIY-PEPNEFRPERFSP--EESAKRPSVAWLP 443 Query: 314 FSMGPRSCIGQNFSMLEAKSTLALMLQKFSF---TLSPD-YVHAPVDIFTLKPKFGLQVF 147 F GPR+CIG F ++A+ LA++++ F+F + +PD P L K G+Q+ Sbjct: 444 FGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQLK 503 Query: 146 VRPL 135 V + Sbjct: 504 VEAI 507
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/115 (34%), Positives = 61/115 (53%) Frame = -1 Query: 572 NKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGD 393 NKL + V+ E+LR++ F+ R+ V + V + +PK I I I + RD + Sbjct: 363 NKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHF-P 421 Query: 392 DADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 D F+P RF T + P + FS G R+CIGQ F++LE K LA +++ F Sbjct: 422 KPDLFQPDRFLPENT-VNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNF 475
>CP27A_RABIT (P17177) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 535 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/153 (30%), Positives = 72/153 (47%), Gaps = 6/153 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVAD--MT 477 PE Q LRKEV+ Q P + + VL ETLRLY P + + + D + Sbjct: 358 PEIQAALRKEVVGVVAAGQVPQHKDFAHMPLLKAVLKETLRLY-PVIPANSRIIVDKEIE 416 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGITGAAKVPH--GLLAFSM 306 VG PK V + RD + + D F P R+ + G +K H G + F Sbjct: 417 VGGFLFPKNTQFVFCHYVTSRDPSTFSEP-DTFWPYRWLRKGQPETSKTQHPFGSVPFGY 475 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 G R+C+G+ + LE + LA ++Q++ L+P+ Sbjct: 476 GVRACLGRRIAELEMQLLLARLIQRYELMLAPE 508
>CP6G1_DROME (Q9V674) Cytochrome P450 6g1 (EC 1.14.-.-) (CYPVIG1) (Cyp6-like| protein) Length = 524 Score = 58.9 bits (141), Expect = 1e-08 Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 14/155 (9%) Frame = -1 Query: 647 PEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRK--TVADM 480 PE Q+RLR E+ + G S + L+ + MV+ E LR+Y F+ R+ +V Sbjct: 332 PEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQ 391 Query: 479 TVGSLK------LPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKVP 330 SLK L G + IPI +H D + W + D + F P KN I A P Sbjct: 392 PDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKN-IVAMAYQP 450 Query: 329 HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 225 F GP +CIG +L++K L +L+ S Sbjct: 451 -----FGSGPHNCIGSRIGLLQSKLGLVSLLKNHS 480
>CP1A1_RABIT (P05176) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450 isozyme| 6) (P-450 PHPAH1) (P450 LM6) Length = 518 Score = 58.9 bits (141), Expect = 1e-08 Identities = 44/149 (29%), Positives = 72/149 (48%), Gaps = 3/149 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 P Q ++++E+ G + P + +L + V+ ET R S F + T D ++ Sbjct: 341 PRIQRKIQEELDAVVGRARRPRFSDRPQLPYLEAVIMETFRHTSFLPFTIPHSTTRDTSL 400 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAK-VPHGLLAFSMGPR 297 G +PKG + + + D E+WGD + F+P RF K + +L F +G R Sbjct: 401 GGFYIPKGRCVFVNQWQNNHDPELWGDP-EAFRPERFLTPSGAVDKALTEKVLLFGLGKR 459 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 CIG+ LE LA +LQ+ F++SP Sbjct: 460 KCIGETIGRLEVFLFLATLLQQVEFSVSP 488
>CP17A_HORSE (Q95328) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 58.9 bits (141), Expect = 1e-08 Identities = 40/153 (26%), Positives = 79/153 (51%), Gaps = 4/153 (2%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ ++++++E+ + G ++P + N+L + + E LR+ A + + K + D Sbjct: 320 HDPQLKKKIQEEIDQNVGFSRTPTLSDRNRLLLLEATIREVLRIRPVAPMLIPHKALVDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSM 306 ++G + G ++I + +H +++ W D F P RF + TG+ + L L F Sbjct: 380 SIGEFAVDDGTNVIINLWALHHNEKEW-HQPDRFMPERFLDP-TGSQLISPSLSYLPFGA 437 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 GPRSCIG+ + E A +LQ+F+ + D Sbjct: 438 GPRSCIGELLARQELFLFTAWLLQRFNLEVPDD 470
>C97B1_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2)| Length = 552 Score = 58.9 bits (141), Expect = 1e-08 Identities = 50/168 (29%), Positives = 76/168 (45%), Gaps = 29/168 (17%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLY-SPALFMQRKTVADM 480 A P+ ++ + EV GM P L KL+ + +++ ETLRLY P L ++R D+ Sbjct: 379 AQNPDKMKKAQAEVDLVLGMGKPTFELLKKLEYIRLIVVETLRLYPQPPLLIRRSLKPDV 438 Query: 479 TVGSLK-------LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--------KNGITG 345 G K +P G + I + +HR W D ++F+P RF G G Sbjct: 439 LPGGHKGDKDGYTIPAGTDVFISVYNLHRSPYFW-DRPNDFEPERFLVQNNNEEVEGWAG 497 Query: 344 -------AAKVPH------GLLAFSMGPRSCIGQNFSMLEAKSTLALM 240 A P+ L F GPR C+G F+++E ST+AL+ Sbjct: 498 FDPSRSPGALYPNEIISDFAFLPFGGGPRKCVGDQFALME--STVALV 543
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 58.9 bits (141), Expect = 1e-08 Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 16/156 (10%) Frame = -1 Query: 647 PEWQERLRKEVLKEFG------MQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVA 486 P +L++E+ + FG + +L K + + V+ E LRLY P++ + + Sbjct: 337 PRVFNKLKEEIYEAFGKGDDARVSEITFESLKKCEYLKWVMNEMLRLY-PSVPVNFRVAT 395 Query: 485 DMTV----------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAK 336 T + + KG + + HR +E +G DADEFKP R+ + K Sbjct: 396 KRTTLPRGGGPDGNSPIYVGKGTTVAYSVYSTHRMEEYYGKDADEFKPERWAE----SRK 451 Query: 335 VPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 + + F+ GPR C+GQ F++ EA + +LQ F Sbjct: 452 LGWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMF 487
>CCD1D_DROME (Q7KR10) Probable cytochrome P450 12d1 distal, mitochondrial| precursor (EC 1.14.-.-) (CYPXIID1) Length = 521 Score = 58.9 bits (141), Expect = 1e-08 Identities = 45/172 (26%), Positives = 80/172 (46%), Gaps = 6/172 (3%) Frame = -1 Query: 665 ICSAYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTM---VLFETLRLYSPALFMQRK 495 +C + P+ Q +LR+E+L + N N +K+M V+ ETLR Y R Sbjct: 339 LCLSKHPDKQAKLREELLSIMPTKDSLLNEEN-MKDMPYLRAVIKETLRYYPNGFGTMRT 397 Query: 494 TVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKV---PHG 324 D+ + ++PKG +++ ++ ++ + DEF P R+ K+ P Sbjct: 398 CQNDVILSGYRVPKGTTVLLGSNVLMKEATYY-PRPDEFLPERWLRDPETGKKMQVSPFT 456 Query: 323 LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKP 168 L F GPR CIG+ LE ++T+A +++ F + D +F ++P Sbjct: 457 FLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEP 508
>CP17A_CAPHI (Q9N0U7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 58.5 bits (140), Expect = 2e-08 Identities = 40/151 (26%), Positives = 76/151 (50%), Gaps = 4/151 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P ++R++ + + G ++P + N L + + E LR+ A + + K + D ++ Sbjct: 322 PSLKKRIQDSIDQNIGFNRTPTISDRNCLVLLEATIREVLRIRPVAPMLIPHKAIIDSSI 381 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSMGP 300 G L + KG +V+ + +H +++ W D F P RF + TG + L L F GP Sbjct: 382 GDLTIDKGTDVVVNLWALHHNEKEW-QQPDLFMPERFLDP-TGTQLISPSLSYLPFGAGP 439 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 RSC+G+ + E ++ +LQ+F+ + D Sbjct: 440 RSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>CP17A_BOVIN (P05185) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/151 (27%), Positives = 76/151 (50%), Gaps = 4/151 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P ++R++ ++ + G ++P + N+L + + E LR+ A + K V D ++ Sbjct: 322 PSLKKRIQDDIDQIIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSI 381 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSMGP 300 G L + KG +V+ + +H ++ W D F P RF + TG + L L F GP Sbjct: 382 GDLTIDKGTDVVVNLWALHHSEKEW-QHPDLFMPERFLDP-TGTQLISPSLSYLPFGAGP 439 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 RSC+G+ + E ++ +LQ+F+ + D Sbjct: 440 RSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>CP6W1_DROME (Q9V9L1) Probable cytochrome P450 6w1 (EC 1.14.-.-) (CYPVIW1)| Length = 514 Score = 58.5 bits (140), Expect = 2e-08 Identities = 41/150 (27%), Positives = 77/150 (51%), Gaps = 11/150 (7%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPNALNKLKEM---TMVLFETLRLYSPALFMQRKTVADMT--- 477 Q+RLR+E++ FG + D + +++EM + V+ ETLR Y +++R+ Sbjct: 328 QDRLRQEIVDFFGDE--DHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGER 385 Query: 476 -----VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAF 312 +++LP G++I + +HRD + W D +++ P RF + + + F Sbjct: 386 FTLEPFHNMELPHGMSIYMSTVAVHRDPQYW-PDPEKYDPERFNSSNRDNLNMD-AYMPF 443 Query: 311 SMGPRSCIGQNFSMLEAKSTLALMLQKFSF 222 +GPR+CIG +L++K L +L+ F Sbjct: 444 GVGPRNCIGMRLGLLQSKLGLVHILRNHRF 473
>C77A2_SOLME (P37124) Cytochrome P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2)| (P-450EG5) Length = 511 Score = 58.5 bits (140), Expect = 2e-08 Identities = 49/181 (27%), Positives = 82/181 (45%), Gaps = 11/181 (6%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMT-VG 471 P Q +L +E+ K G D + K+ + V+ E LR + P V + +G Sbjct: 335 PNIQSQLYEEIKKTVGENKIDEKDIEKMPYLNAVVKELLRKHPPTYMSLTHAVTEPAKLG 394 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG-----ITGAAKVPHGLLAFSM 306 +P G+ + I +P + D +W + ++F P RF G ITG + V ++ F M Sbjct: 395 GYDIPTGVNVEIFLPGISDDPNLWSEP-EKFDPDRFYLGKEDADITGVSGVK--MIPFGM 451 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI-----FTLKPKFGLQVFVR 141 G R C G N + + LA ++Q+F + D + VD FT+ K L+ ++ Sbjct: 452 GRRICPGLNMATVHVSLMLARLVQEFEWA---DPENTRVDFTEKLEFTVVMKNTLRAKIK 508 Query: 140 P 138 P Sbjct: 509 P 509
>CP6T3_DROME (Q9V676) Probable cytochrome P450 6t3 (EC 1.14.-.-) (CYPVIT3)| Length = 501 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/155 (29%), Positives = 73/155 (47%), Gaps = 12/155 (7%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEF-GMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A P+ QERLR E+ + F + + L L + MV E LRLY A F+ R+ + Sbjct: 317 AKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALRLYPAAAFVNRECTSSA 376 Query: 479 TVG-SLK------LPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRFKNGITGAAKV 333 + G SL+ +P G+ I I +HRD+ W + D + F P R ++ Sbjct: 377 SEGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPERFGPERSRH------IH 430 Query: 332 PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 P + F GP CIG +L+ K + +L+++ Sbjct: 431 PMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQY 465
>CPXN_ANASP (P29980) Probable cytochrome P450 110 (EC 1.14.-.-)| Length = 459 Score = 58.5 bits (140), Expect = 2e-08 Identities = 49/171 (28%), Positives = 86/171 (50%), Gaps = 6/171 (3%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYS--PALFMQRKTVADMTVGSL 465 QE+L++E L G +P+P + +L +T V ETLR+Y P LF R T + + + Sbjct: 284 QEKLQQE-LDRLGA-NPNPMEIAQLPYLTAVSQETLRMYPVLPTLF-PRITKSSINIAGY 340 Query: 464 KLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIG 285 +L ++ I ++H ++++ + +F+P RF P + F G R C+G Sbjct: 341 QLEPDTTLMASIYLIHYREDLY-PNPQQFRPERF----IERQYSPSEYIPFGGGSRRCLG 395 Query: 284 QNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI----FTLKPKFGLQVFV 144 ++LE K +A +L + L+ D PV++ FTL P G++V + Sbjct: 396 YALALLEIKLVIATVLSNYQLALAED---KPVNVQRRGFTLAPDGGVRVIM 443
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 58.2 bits (139), Expect = 2e-08 Identities = 38/152 (25%), Positives = 75/152 (49%), Gaps = 4/152 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 PE Q+++++E+ G + +P + + + + E LR+ + L + +AD ++ Sbjct: 325 PEVQKKIQEEIDSNIGFERTPKMSDKGNMNFLNATIHEILRIQPVSPLLIPHVALADSSI 384 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KNGITGAAKVPHGLLAFSMGP 300 G +PKG ++I + +H D++ W + D F P RF ++G L F G Sbjct: 385 GDYTIPKGTRVIINLWAIHHDEKEW-KNPDAFDPGRFLDEDG-KYVCSSSESYLPFGAGT 442 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY 204 R C+G+ + +E + +LQ+F+ + P Y Sbjct: 443 RVCLGEMLARMELFLFTSWILQRFTVQVPPGY 474
>CP17A_BISBI (Q9GMC7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 58.2 bits (139), Expect = 2e-08 Identities = 41/151 (27%), Positives = 76/151 (50%), Gaps = 4/151 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P ++R++ ++ + G ++P + N+L + + E LR+ A + K V D ++ Sbjct: 322 PSLKKRIQDDIDQIIGFNRTPAISDRNRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSI 381 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSMGP 300 G L + KG +V+ + +H ++ W D F P RF + TG + L L F GP Sbjct: 382 GDLTIDKGTDVVVNLWALHHSEKEW-QHPDLFMPERFLDP-TGTQLISPSLSYLPFGAGP 439 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 RSC+G+ + E ++ +LQ+F+ + D Sbjct: 440 RSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>CP191_CARAU (P79690) Cytochrome P450 19 type 1 (EC 1.14.14.1) (Brain aromatase)| (CYPXIXA1) (Estrogen synthetase) (P-450AROM) Length = 510 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/138 (23%), Positives = 70/138 (50%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKL 459 +E++ +E+ + G + + L KL + + E+LR + F+ R+ + D + ++ Sbjct: 327 EEQIVQEIQSQIGERDVESADLQKLNVLERFIKESLRFHPVVDFIMRRALEDDEIDGYRV 386 Query: 458 PKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQN 279 KG +++ I MH+ + + +EF F+N + P F GPR+C+G++ Sbjct: 387 AKGTNLILNIGRMHKSE--FFQKPNEFNLENFENTVPSRYFQP-----FGCGPRACVGKH 439 Query: 278 FSMLEAKSTLALMLQKFS 225 +M+ K+ L +L +F+ Sbjct: 440 IAMVMTKAILVTLLSRFT 457
>CP6D1_MUSDO (Q27698) Cytochrome P450 6d1 (EC 1.14.-.-) (CYPVID1) (Pyrethroid| resistance cytochrome P450) (Cytochrome P450 Ipr) Length = 516 Score = 58.2 bits (139), Expect = 2e-08 Identities = 44/147 (29%), Positives = 68/147 (46%), Gaps = 2/147 (1%) Frame = -1 Query: 644 EWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSL 465 E E L++ LK G + + A+ +K + + + ET R Y F+ RK D V Sbjct: 347 EVDECLQRHGLKPQGRLTYE--AIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDT 404 Query: 464 KL--PKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 KL PK I+I + +HRD + + D ++P RF + P + F GPR C Sbjct: 405 KLTIPKETGIIISLLGIHRDPQYFPQPED-YRPERFAD--ESKDYDPAAYMPFGEGPRHC 461 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTLSP 210 I Q ++ +K LA +L F+ P Sbjct: 462 IAQRMGVMNSKVALAKILANFNIQPMP 488
>C4AD1_DROME (Q9V4T3) Probable cytochrome P450 4ad1 (EC 1.14.-.-) (CYPIVAD1)| Length = 516 Score = 58.2 bits (139), Expect = 2e-08 Identities = 42/154 (27%), Positives = 76/154 (49%), Gaps = 8/154 (5%) Frame = -1 Query: 644 EWQERLRKEVLKEFGMQ---SPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTV 474 E Q++ +E + FG D L+++ + +++ ETLRLY + R + + Sbjct: 326 EIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI 385 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN-----GITGAAKVPHGLLAFS 309 K+ K +++ + M +++ + DD F+P RF+N GI VP FS Sbjct: 386 NGTKVAKCTTVIMCLIAMGYNEKYF-DDPCTFRPERFENPTGNVGIEAFKSVP-----FS 439 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 GPR CI + F+M + K+ L+ +L++F + D Sbjct: 440 AGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVD 473
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 58.2 bits (139), Expect = 2e-08 Identities = 41/153 (26%), Positives = 76/153 (49%), Gaps = 4/153 (2%) Frame = -1 Query: 653 YTPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADM 480 + P+ +++L + + + G ++P + N+L + + E LR+ A + + K D Sbjct: 320 HNPQVKKKLYEGIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDS 379 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGL--LAFSM 306 ++G + KG ++I + +H +++ W D+F P RF N G + L L F Sbjct: 380 SIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP-AGTQLISPSLSYLPFGA 437 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 GPRSCIG+ + E +A +LQ+F + D Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP52I_CANMA (Q12586) Cytochrome P450 52A9 (EC 1.14.14.-) (CYPLIIA9)| (Alkane-inducible P450-ALK5-A) Length = 521 Score = 58.2 bits (139), Expect = 2e-08 Identities = 49/171 (28%), Positives = 74/171 (43%), Gaps = 16/171 (9%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVLFETLRLYSPALFMQRK 495 A PE RLR+E+ +FG+ +L + + + V+ E LR+Y R Sbjct: 334 ARNPEVWSRLREEIGDKFGLDEDATIEGISFESLKQCEYLKAVVNECLRMYPSVPRNFRI 393 Query: 494 TVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 342 T+ + + KG + I H D +G DA F P R+ T Sbjct: 394 ATKHTTLPRGGGPDGKDPIFIKKGAVVSYGINSTHLDPMYYGPDARLFNPDRWSKPET-- 451 Query: 341 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTLSPDYVHAP 192 K+ L F+ GPR C+GQ F++ EA L M+Q F L+P+ V+ P Sbjct: 452 KKLGWAFLPFNGGPRICLGQQFALTEASYVLVRMIQNFKELELTPNTVYPP 502
>C82A2_SOYBN (O81972) Cytochrome P450 82A2 (EC 1.14.-.-) (P450 CP4)| Length = 522 Score = 57.8 bits (138), Expect = 3e-08 Identities = 44/119 (36%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Frame = -1 Query: 575 LNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVW 399 L+KL + V+ ETLRLY PA L R+ D T+G + KG ++ + +H D VW Sbjct: 363 LSKLTYLQAVVKETLRLYPPAPLSRPREFEEDCTIGGYTVKKGTRLITNLSKIHTDHNVW 422 Query: 398 GDDADEFKPLRFKNGITGA-AKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 + EFKP RF K H LL F G R C G N + + TLA L F Sbjct: 423 SNPL-EFKPERFLTTDKDIDMKGQHFQLLPFGGGRRICPGINLGLQTVRLTLASFLHSF 480
>CP17A_ORYLA (P70085) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 517 Score = 57.8 bits (138), Expect = 3e-08 Identities = 43/167 (25%), Positives = 85/167 (50%), Gaps = 3/167 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 PE Q+++++E+ ++ G+ P + L + + E LR+ A L + ++D ++ Sbjct: 331 PEVQKQIQEELDRKVGVDRPPQLSDRGSLPFLEATIREVLRIRPVAPLLIPHVALSDTSL 390 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG-LLAFSMGPR 297 G + KG +VI + +H D++ W + D F P RF + + +P L F G R Sbjct: 391 GDFTVRKGTRVVINLWSLHHDEKEW-TNPDLFNPGRFLSADGSSLTLPSSSYLPFGAGLR 449 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGL 156 C+G+ + +E L+ +LQ+F+ ++ P + +L+ KFG+ Sbjct: 450 VCLGEALAKMELFLFLSWILQRFTLSVPPSQ-----SLPSLEGKFGV 491
>C81F1_ARATH (O65790) Cytochrome P450 81F1 (EC 1.14.-.-)| Length = 500 Score = 57.8 bits (138), Expect = 3e-08 Identities = 39/144 (27%), Positives = 70/144 (48%), Gaps = 2/144 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPALFM-QRKTVADMTV 474 PE E+ R E+ ++ G D + + L + V+ ET RL+ A F+ R DM + Sbjct: 320 PEVLEKARSEIDEKIGKDRLIDESDIAVLPYLQNVVSETFRLFPVAPFLIPRSPTDDMKI 379 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 G +P+ +++ +HRD E+W ++ ++F P R+ +G G+ + L+ F G R+ Sbjct: 380 GGYDVPRDTIVMVNAWAIHRDPEIW-EEPEKFNPDRYNDG-CGSDYYVYKLMPFGNGRRT 437 Query: 293 CIGQNFSMLEAKSTLALMLQKFSF 222 C G L ++Q F + Sbjct: 438 CPGAGLGQRIVTLALGSLIQCFEW 461
>C71A6_NEPRA (O04164) Cytochrome P450 71A6 (EC 1.14.-.-) (Fragment)| Length = 511 Score = 57.8 bits (138), Expect = 3e-08 Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 7/177 (3%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P + L+KEV G + + + L K+ + V+ E+LRL++P L + R++ D V Sbjct: 331 PRAMKILQKEVRGVAGSKGEIEESDLEKMPYLKAVMKESLRLHAPVPLLVPRESTRDTKV 390 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 + G ++I + RD VW ++++ F P RF + L+ F G R Sbjct: 391 LGYDVASGTRVLINCWAIGRDSSVW-EESETFLPERFLETSIDYRGMHFELIPFGSGRRG 449 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI-----FTLKPKFGLQVFVRP 138 C G F+ + LA ++ KF F L +D+ FT+ KF L V P Sbjct: 450 CPGATFAAAIDELALATLVHKFDFKLPNGVRVEDLDMSEGSGFTIHKKFPLLVVPTP 506
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 57.8 bits (138), Expect = 3e-08 Identities = 51/170 (30%), Positives = 77/170 (45%), Gaps = 7/170 (4%) Frame = -1 Query: 638 QERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKL 459 +E +R + K G + D A++ +K + + ET R Y + R D V KL Sbjct: 341 KEDVRSAIEKHGGKLTYD--AISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKL 398 Query: 458 --PKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNG--ITGAAKVPHGLLAFSMGPRS 294 KG I+I + MHRD+E + D +KP R+ +NG T AA +P F GPR Sbjct: 399 VIQKGTPIIISLIGMHRDEEYFPDPL-AYKPERYLENGKDYTQAAYLP-----FGEGPRM 452 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIF--TLKPKFGLQV 150 CIG + K +A +L F + + ++ L PK G+ V Sbjct: 453 CIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPV 502
>CP1A2_CALJA (O77810) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 57.8 bits (138), Expect = 3e-08 Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 4/168 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 PE Q +++KE+ G + P + +L + + ET R S F + T D T+ Sbjct: 336 PEIQRKIQKELDTVIGRGRRPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTTL 395 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVP--HGLLAFSMGP 300 +PK + I ++ D ++WGD + EF+P RF A P +L F +G Sbjct: 396 KGFYIPKECCVFINQWQVNHDPQLWGDPS-EFRPERFLTAKGTALNKPLSEKILLFGLGK 454 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGL 156 R CIG+ E LA++LQ+ F++ P +D L P +GL Sbjct: 455 RRCIGEVLGKWEVFLFLAILLQQLEFSVPPG---VQID---LTPTYGL 496
>C71AJ_ARATH (Q9T0K0) Cytochrome P450 71A19 (EC 1.14.-.-)| Length = 490 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/119 (30%), Positives = 58/119 (48%), Gaps = 1/119 (0%) Frame = -1 Query: 569 KLKEMTMVLFETLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGD 393 K+ + V+ E LRL PA L + R D+T+ +P G ++I + RD WG Sbjct: 340 KMDYLQAVIKEALRLRPPAPLMVPRVFSEDVTLKGYNIPAGTQVIINAWAIQRDTTTWGI 399 Query: 392 DADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 DA+EF+P R + I + F G R C G F+ TLA ++++F++ + Sbjct: 400 DAEEFRPERHLDSILDFQGQDFKFIPFGSGKRICPGIGFTSALIGVTLANIVKRFNWRM 458
>CP1A2_HUMAN (P05177) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450-P3)| (P(3)450) (P450 4) Length = 514 Score = 57.4 bits (137), Expect = 4e-08 Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 4/150 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 PE Q +++KE+ G + P + +L + + ET R S F + T D T+ Sbjct: 336 PEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTL 395 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVP--HGLLAFSMGP 300 +PK + + ++ D E+W +D EF+P RF A P ++ F MG Sbjct: 396 NGFYIPKKCCVFVNQWQVNHDPELW-EDPSEFRPERFLTADGTAINKPLSEKMMLFGMGK 454 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 R CIG+ + E LA++LQ+ F++ P Sbjct: 455 RRCIGEVLAKWEIFLFLAILLQQLEFSVPP 484
>CP1A1_MOUSE (P00184) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1)| Length = 524 Score = 57.4 bits (137), Expect = 4e-08 Identities = 41/149 (27%), Positives = 72/149 (48%), Gaps = 3/149 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 P Q ++++E+ G + P + +L + + ET R S F + T D ++ Sbjct: 341 PRVQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTSL 400 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI-TGAAKVPHGLLAFSMGPR 297 +PKG + + ++ D+E+WGD +EF+P RF T ++ + F +G R Sbjct: 401 NGFYIPKGCCVFVNQWQVNHDRELWGDP-NEFRPERFLTPSGTLDKRLSEKVTLFGLGKR 459 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 CIG+ E LA++LQ+ F +SP Sbjct: 460 KCIGETIGRSEVFLFLAILLQQIEFKVSP 488
>CP1A1_MESAU (Q00557) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P-450MC)| Length = 524 Score = 57.4 bits (137), Expect = 4e-08 Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 2/123 (1%) Frame = -1 Query: 572 NKLKEMTMVLFETLRLYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWG 396 ++L + + ET R S F + T D ++ +PKG + + ++ ++E+WG Sbjct: 367 SQLPYLEAFILETFRHSSFLPFTIPHSTTRDTSLCGFYIPKGHCVFVNQWQINHNQELWG 426 Query: 395 DDADEFKPLRFKNGITGAAKVPHGLLA-FSMGPRSCIGQNFSMLEAKSTLALMLQKFSFT 219 D ++F+P RF KV G + F +G R CIG+ LE LA++LQ+ FT Sbjct: 427 DP-NKFRPERFLTSSGTLDKVLSGKVTLFGLGKRKCIGETIGRLEVFLFLAILLQQIEFT 485 Query: 218 LSP 210 +SP Sbjct: 486 VSP 488
>C71AE_ARATH (P58045) Cytochrome P450 71A14 (EC 1.14.-.-)| Length = 497 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 1/140 (0%) Frame = -1 Query: 566 LKEMTMVLFETLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDD 390 +K + V+ E LRL+ P L + R+ D+ + + G ++I + RD WG D Sbjct: 348 MKYLKAVVKEVLRLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGID 407 Query: 389 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 A+EF+P R + + + F G R C G F+M + TLA ++ +F++ + Sbjct: 408 AEEFRPERHLDSLVDFRGTNFEFIPFGSGRRICPGIGFAMALVEVTLANLVNRFNWRME- 466 Query: 209 DYVHAPVDIFTLKPKFGLQV 150 V D + L GL V Sbjct: 467 --VQHSGDEYDLAESTGLDV 484
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 57.4 bits (137), Expect = 4e-08 Identities = 40/115 (34%), Positives = 61/115 (53%) Frame = -1 Query: 572 NKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGD 393 N+L M V+ E+LRL+ F+ R+ V + V L +PK I I + + RD + + Sbjct: 350 NELVYMECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARHFSN 409 Query: 392 DADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 F+P RF T + P + FS G R+CIGQ F++LE K LA +++ F Sbjct: 410 PK-MFQPDRFFPENT-VNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNF 462
>T13H_TAXCU (Q8W4T9) Taxane 13-alpha-hydroxylase (EC 1.14.13.77) (Cytochrome| P450 725A2) Length = 485 Score = 57.4 bits (137), Expect = 4e-08 Identities = 48/148 (32%), Positives = 70/148 (47%), Gaps = 7/148 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP----DPNALNKLKEMT---MVLFETLRLYSPALFMQRKTV 489 PE E++ +E +FG+ S + A LKEM V+ ETLR+Y P RK + Sbjct: 312 PESYEKVAQE---QFGILSTKMEGEEIAWKDLKEMKYSWQVVQETLRMYPPIFGTFRKAI 368 Query: 488 ADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 D+ +PKG + + + KE + DAD+FKP RF+ G P+ L F Sbjct: 369 TDIHYNGYTIPKGWKL-LWTTYSTQTKEEYFKDADQFKPSRFEE--EGKHVTPYTYLPFG 425 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFS 225 G R C G F+ +E L ++ FS Sbjct: 426 GGMRVCPGWEFAKMETLLFLHHFVKAFS 453
>C71D8_SOYBN (O81974) Cytochrome P450 71D8 (EC 1.14.-.-) (P450 CP7)| Length = 504 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 1/145 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEF-GMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 P+ +E+ + E+ + F G + L +L + V+ ETLRL+ P+ + R+ + + Sbjct: 326 PKVKEKAQAELRQIFKGKEIIRETDLEELSYLKSVIKETLRLHPPSQLIPRECIISTNID 385 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 ++P ++I + RD + W D AD F P RF + + F G R C Sbjct: 386 GYEIPIKTKVMINTWAIGRDPQYWSD-ADRFIPERFNDSSIDFKGNSFEYIPFGAGRRMC 444 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTL 216 G F + LAL+L F++ L Sbjct: 445 PGMTFGLASITLPLALLLYHFNWEL 469
>C76A2_SOLME (P37122) Cytochrome P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7)| Length = 505 Score = 57.0 bits (136), Expect = 5e-08 Identities = 46/156 (29%), Positives = 70/156 (44%), Gaps = 7/156 (4%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA------LNKLKEMTMVLFETLRLYSPALFM-QRKTV 489 PE +++ E+ Q+ +PN + L M VL E+LRL+ P F+ R+T+ Sbjct: 329 PEAMAKVKTEI-----SQAIEPNRKFEDSDIENLPYMQAVLKESLRLHPPLPFLIPRETI 383 Query: 488 ADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFS 309 D +PK +++ + RD E W DD FKP RF +GL+ F Sbjct: 384 QDTKFMGYDVPKDTQVLVNAWAIGRDPECW-DDPMSFKPERFLGSKIDVKGQHYGLIPFG 442 Query: 308 MGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYV 201 G R C+G L +L++F + L PD V Sbjct: 443 AGRRMCVGLPLGHRMMHFALGSLLREFEWEL-PDGV 477
>C76A1_SOLME (P37121) Cytochrome P450 76A1 (EC 1.14.-.-) (CYPLXXVIA1) (P-450EG8)| (Fragment) Length = 467 Score = 57.0 bits (136), Expect = 5e-08 Identities = 41/146 (28%), Positives = 64/146 (43%), Gaps = 2/146 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNA-LNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P+ +++ E+L+ G ++ L M VL E LRL+ P L + RK + D Sbjct: 291 PQAMAKVKLEILQVIGPNKKFEECDIDSLPYMQAVLKEQLRLHPPLPLLIPRKAIQDTKF 350 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 +PKG +++ + RD E W D+ EFKP RF + L+ F G R Sbjct: 351 MGYDIPKGTQVLVNAWAIGRDPEYW-DNPFEFKPERFLESKVDVKGQNYELIPFGAGRRM 409 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTL 216 C+G T +L +F + L Sbjct: 410 CVGLPLGHRMMHFTFGSLLHEFDWEL 435
>CP2J6_MOUSE (O54750) Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic| acid epoxygenase) Length = 501 Score = 57.0 bits (136), Expect = 5e-08 Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 2/147 (1%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPA--LFMQRKTVAD 483 A PE QE+++ E+ + G + A + T + +R L + R+ D Sbjct: 327 ALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVRRMGNIIPLNVPREVAMD 386 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMG 303 + LPKG ++ + +HRD + W D F P F G K L FSMG Sbjct: 387 TNLNGFHLPKGTMVLTNLTALHRDPKEWATP-DVFNPEHFLEN--GQFKKRESFLPFSMG 443 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKFSF 222 R+C+G+ + E ++QKF+F Sbjct: 444 KRACLGEQLARSELFIFFTSLMQKFTF 470
>CP1A2_RABIT (P00187) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450 isozyme| 4) (P450-PM4) (P450 LM4) Length = 515 Score = 57.0 bits (136), Expect = 5e-08 Identities = 48/168 (28%), Positives = 77/168 (45%), Gaps = 4/168 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 P Q ++++E+ G + P + +L + + E R S F + T D T+ Sbjct: 336 PRRQRKIQEELDAVVGRARQPRLSDRPQLPYLEAFILELFRHTSFVPFTIPHSTTRDTTL 395 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVP--HGLLAFSMGP 300 +PK I I ++ D ++WGD +EF+P RF A P + F +G Sbjct: 396 NGFHIPKECCIFINQWQINHDPQLWGDP-EEFRPERFLTADGAAINKPLSEKVTLFGLGK 454 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPKFGL 156 R CIG+ + E LA++LQ+ F++ P PVD L P +GL Sbjct: 455 RRCIGETLARWEVFLFLAILLQRLEFSVPPG---VPVD---LTPIYGL 496
>CP1A2_MACFU (Q4H4C3) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 57.0 bits (136), Expect = 5e-08 Identities = 42/150 (28%), Positives = 72/150 (48%), Gaps = 4/150 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 PE Q +++KE+ G + P + +L + + ET R S F + T D T+ Sbjct: 336 PEIQRKIQKELDAVIGRGRRPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTTL 395 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KNGITGAAKVPHGLLAFSMGP 300 +P+ + I ++ D ++WGD + EF+P RF G T + ++ F +G Sbjct: 396 NGFYIPRECCVFINQWQVNHDPQLWGDPS-EFRPERFLTAEGTTINKPLSEKIMLFGLGK 454 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 R CIG+ E LA++LQ+ F++ P Sbjct: 455 RRCIGEVLGKWEVFLFLAILLQQLEFSVPP 484
>CP1A2_MACFA (O77809) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 57.0 bits (136), Expect = 5e-08 Identities = 42/150 (28%), Positives = 72/150 (48%), Gaps = 4/150 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALF-MQRKTVADMTV 474 PE Q +++KE+ G + P + +L + + ET R S F + T D T+ Sbjct: 336 PEIQRKIQKELDAVIGRGRRPRLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTTL 395 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KNGITGAAKVPHGLLAFSMGP 300 +P+ + I ++ D ++WGD + EF+P RF G T + ++ F +G Sbjct: 396 NGFYIPRECCVFINQWQVNHDPQLWGDPS-EFRPERFLTAEGTTINKPLSEKIMLFGLGK 454 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 R CIG+ E LA++LQ+ F++ P Sbjct: 455 RRCIGEVLGKWEVFLFLAILLQQLEFSVPP 484
>C71A1_PERAE (P24465) Cytochrome P450 71A1 (EC 1.14.-.-) (CYPLXXIA1) (ARP-2)| Length = 471 Score = 57.0 bits (136), Expect = 5e-08 Identities = 40/146 (27%), Positives = 74/146 (50%), Gaps = 2/146 (1%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTV 474 P+ E+ ++EV + G ++ + L++L + +++ ETLRL+ A L + R++ D+ + Sbjct: 324 PDVMEKAQQEVRRVVGKKAKVEEEDLHQLHYLKLIIKETLRLHPVAPLLVPRESTRDVVI 383 Query: 473 GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRS 294 +P + I + RD + W ++A+EF P RF N L+ F G R Sbjct: 384 RGYHIPAKTRVFINAWAIGRDPKSW-ENAEEFLPERFVNNSVDFKGQDFQLIPFGAGRRG 442 Query: 293 CIGQNFSMLEAKSTLALMLQKFSFTL 216 C G F + + +LA +L F++ L Sbjct: 443 CPGIAFGISSVEISLANLLYWFNWEL 468
>C71B8_ARATH (P58048) Cytochrome P450 71B8 (EC 1.14.-.-)| Length = 506 Score = 56.6 bits (135), Expect = 7e-08 Identities = 41/147 (27%), Positives = 68/147 (46%), Gaps = 3/147 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSP--DPNALNKLKEMTMVLFETLRLYSPALFM-QRKTVADMT 477 P ++LR+E+ G L K++ + +V+ ET RL+ P F+ R+ ++D+ Sbjct: 323 PRVMKKLREEIRATLGPNKERITEEDLEKVEYLKLVIKETFRLHPPGPFLLPRQVMSDIE 382 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPR 297 + +PK I I + RD + W + +EF P RF N + LL F G R Sbjct: 383 IQGYHIPKNAHIKISTYAIGRDPKCW-TNPEEFNPERFANTSINYKGQHYELLPFGAGRR 441 Query: 296 SCIGQNFSMLEAKSTLALMLQKFSFTL 216 SC G + + L +L F ++L Sbjct: 442 SCPGMTLGITILELGLLNILYYFDWSL 468
>C94A1_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 514 Score = 56.6 bits (135), Expect = 7e-08 Identities = 40/145 (27%), Positives = 72/145 (49%), Gaps = 10/145 (6%) Frame = -1 Query: 632 RLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFETLRLYSPALFMQRKTVADMTV-GSL 465 R+ +E++ E +S + +++KEM L E++RLY P ++ V D + Sbjct: 336 RVEEEIVNELSKKS-ELMVYDEVKEMVYTHAALSESMRLYPPVPMDSKEAVNDDVLPDGW 394 Query: 464 KLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KNGITG----AAKVPHGLLAFSMG 303 + KG + + M R K +WGDD EF+P R+ K+ + G + + F G Sbjct: 395 VVKKGTIVTYHVYAMGRMKSLWGDDWAEFRPERWLEKDEVNGKWVFVGRDSYSYPVFQAG 454 Query: 302 PRSCIGQNFSMLEAKSTLALMLQKF 228 PR C+G+ + ++ K +A ++ KF Sbjct: 455 PRVCLGKEMAFMQMKRIVAGIVGKF 479
>CP27A_HUMAN (Q02318) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 531 Score = 56.6 bits (135), Expect = 7e-08 Identities = 44/151 (29%), Positives = 68/151 (45%), Gaps = 4/151 (2%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVG 471 PE QE L +EV+ Q P + + VL ETLRLY R ++ V Sbjct: 355 PEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVD 414 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP---LRFKNGITGAAKVPHGLLAFSMGP 300 PK V ++ RD + + + F+P LR T + P G + F G Sbjct: 415 GFLFPKNTQFVFCHYVVSRDPTAFSEP-ESFQPHRWLRNSQPATPRIQHPFGSVPFGYGV 473 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 207 R+C+G+ + LE + LA ++QK+ L+P+ Sbjct: 474 RACLGRRIAELEMQLLLARLIQKYKVVLAPE 504
>CP308_DROME (Q9VWR2) Probable cytochrome P450 308a1 (EC 1.14.-.-)| (CYPCCCVIIIA1) Length = 490 Score = 56.6 bits (135), Expect = 7e-08 Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 10/137 (7%) Frame = -1 Query: 587 DPNALNKLKEMTMVLFETLRLYSPALFMQRK-----TVADMTVGS---LKLPKGIAIVIP 432 DP AL +L+ L E LRL+ +Q++ T+ D G+ LK+ G +V+P Sbjct: 330 DPVALGELRYSEAALLEALRLHPAMQALQKRCTKTFTLPDQKSGASSELKVHLGTVLVLP 389 Query: 431 IPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAK 258 + +H D ++ ++F+P RF N + P G L F GPR C G +L+ K Sbjct: 390 VQAIHLDPALY-PAPNQFRPERFLN------QPPMGCRFLGFGAGPRMCPGMRLGLLQTK 442 Query: 257 STLALMLQKFSFTLSPD 207 + L +LQ L+ + Sbjct: 443 AALTTLLQDHCVQLADE 459
>C11B1_SHEEP (P51663) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 56.6 bits (135), Expect = 7e-08 Identities = 40/144 (27%), Positives = 72/144 (50%), Gaps = 1/144 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN-ALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE Q+ LR+E L S +P A +L + L ETLRLY + ++R+ +D+ Sbjct: 331 ARNPEVQQALRQESLVAEARISENPQRATTELPLLRAALKETLRLYPVGITLERQVSSDL 390 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +P G + + + + R+ V+ + + P R+ + ++ PH LAF G Sbjct: 391 VLQNYHIPAGTLVKVLLYSLGRNPAVFA-RPESYHPQRWLDRQGSGSRFPH--LAFGFGM 447 Query: 299 RSCIGQNFSMLEAKSTLALMLQKF 228 R C+G+ + +E L +L+ F Sbjct: 448 RQCLGRRVAEVEMLLLLHHVLKNF 471
>C11B1_BOVIN (P15150) Cytochrome P450 11B1, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB1) (P450C11) (Steroid 11-beta-hydroxylase) Length = 503 Score = 56.6 bits (135), Expect = 7e-08 Identities = 39/144 (27%), Positives = 73/144 (50%), Gaps = 1/144 (0%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPN-ALNKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A PE Q+ +R+E L S +P A+ +L + L ETLRLY + ++R+ +D+ Sbjct: 331 ARNPEVQQAVRQESLVAEARISENPQRAITELPLLRAALKETLRLYPVGITLEREVSSDL 390 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +P G + + + + R+ V+ + + P R+ + ++ PH LAF G Sbjct: 391 VLQNYHIPAGTLVKVLLYSLGRNPAVFA-RPESYHPQRWLDRQGSGSRFPH--LAFGFGV 447 Query: 299 RSCIGQNFSMLEAKSTLALMLQKF 228 R C+G+ + +E L +L+ F Sbjct: 448 RQCLGRRVAEVEMLLLLHHVLKNF 471
>C49A1_DROME (Q9V5L3) Probable cytochrome P450 49a1 (EC 1.14.-.-) (CYPXLIXA1)| Length = 589 Score = 56.6 bits (135), Expect = 7e-08 Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 10/153 (6%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPD--PNALNKLKEMTMVLFETLRLYSPALFMQRKTVAD 483 A P+ Q++L E+ K F + D N L ++ + + ETLR+ + R +D Sbjct: 406 AKNPDKQKKLFDELQKVFPHREADINQNVLEQMPYLRACVKETLRMRPVVIANGRSLQSD 465 Query: 482 MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHG------- 324 + +PKG ++ P ++ D + + F P R+ T AA PH Sbjct: 466 AVINGYHVPKGTHVIFPHLVVSND-PAYFPEPKRFLPERWLKQSTDAAGCPHANQKIHPF 524 Query: 323 -LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 L F G R C+G+ F+ +E + LA + +K+ Sbjct: 525 VSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKY 557
>CP27A_RAT (P17178) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 56.6 bits (135), Expect = 7e-08 Identities = 46/152 (30%), Positives = 71/152 (46%), Gaps = 6/152 (3%) Frame = -1 Query: 647 PEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRK-TVADMT 477 PE QE L KEV + FG + P + + V+ ETLRLY R T + Sbjct: 357 PEIQEALHKEVTGVVPFG-KVPQNKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETE 415 Query: 476 VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP---LRFKNGITGAAKVPHGLLAFSM 306 + PK V+ ++ RD V+ + + F+P LR + + P G + F Sbjct: 416 INGFLFPKNTQFVLCHYVVSRDPSVF-PEPESFQPHRWLRKREDDNSGIQHPFGSVPFGY 474 Query: 305 GPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 210 G RSC+G+ + LE + L+ ++QK+ LSP Sbjct: 475 GVRSCLGRRIAELEMQLLLSRLIQKYEVVLSP 506
>KO1_ARATH (Q93ZB2) Ent-kaurene oxidase (EC 1.14.13.78) (AtKO1) (Cytochrome| P450 701A3) Length = 509 Score = 56.2 bits (134), Expect = 9e-08 Identities = 44/145 (30%), Positives = 67/145 (46%), Gaps = 1/145 (0%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTVG 471 P Q+RL KE+ G + L+++ + V ETLR YSPA L R D +G Sbjct: 336 PSVQDRLCKEIQNVCGGEKFKEEQLSQVPYLNGVFHETLRKYSPAPLVPIRYAHEDTQIG 395 Query: 470 SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSC 291 +P G I I I + DK+ W + +++ P RF + H +AF G R C Sbjct: 396 GYHVPAGSEIAINIYGCNMDKKRW-ERPEDWWPERFLDDGKYETSDLHKTMAFGAGKRVC 454 Query: 290 IGQNFSMLEAKSTLALMLQKFSFTL 216 G + L A + ++Q+F + L Sbjct: 455 AGALQASLMAGIAIGRLVQEFEWKL 479
>CP11B_RANCA (Q92104) Cytochrome P450 11B, mitochondrial precursor (EC| 1.14.15.4) (CYPXIB) (P450C11) (Steroid 11-beta-hydroxylase) (P-450(11 beta,aldo)) Length = 517 Score = 56.2 bits (134), Expect = 9e-08 Identities = 51/176 (28%), Positives = 76/176 (43%), Gaps = 2/176 (1%) Frame = -1 Query: 656 AYTPEWQERLRKEVLKEFGMQSPDPNAL-NKLKEMTMVLFETLRLYSPALFMQRKTVADM 480 A P Q LR+E+ K D N L N L + + ETLRLY + +QR + D+ Sbjct: 348 ARNPSVQRELREEIRKAEAQNPNDLNQLLNSLPLLKGAIKETLRLYPVGITVQRHLIKDI 407 Query: 479 TVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGP 300 + + +P G + + + M R ++ DA + P R+ K LAF G Sbjct: 408 VLHNYHIPAGTLVQVGLYPMGRSPLLF-QDALRYDPARWLKREDTNFKA----LAFGFGS 462 Query: 299 RSCIGQNFSMLEAKSTLALMLQKFSF-TLSPDYVHAPVDIFTLKPKFGLQVFVRPL 135 R CIG+ + E L ML+ F T+S D + + K L F RP+ Sbjct: 463 RQCIGRRIAETEITLFLMHMLKNFQIDTVSKDDIKTVFGFILMPEKPPLLTF-RPI 517
>CP19A_ANGJA (Q6QHT9) Cytochrome P450 19A1 (EC 1.14.14.1) (Aromatase) (CYPXIX)| (Estrogen synthetase) (P-450AROM) Length = 511 Score = 56.2 bits (134), Expect = 9e-08 Identities = 38/141 (26%), Positives = 70/141 (49%) Frame = -1 Query: 647 PEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGS 468 PE ++ + KE+ G + + + L L M + E+LR + F RK++ D + Sbjct: 339 PEVEQEILKELDTVIGDKKAENSNLQHLIIMESFINESLRYHPVVDFTMRKSLEDDVIEG 398 Query: 467 LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCI 288 K+ KG I++ + MH+ + + +EF F+ + P F GPRSC+ Sbjct: 399 YKVFKGTNIILNVGRMHKCE--FFSKPNEFSLENFEKTVPNRFFQP-----FGSGPRSCV 451 Query: 287 GQNFSMLEAKSTLALMLQKFS 225 G++ SM+ K+ LA +L +++ Sbjct: 452 GKHISMVMMKAILATLLSRYT 472
>CP316_DROME (Q9VS78) Probable cytochrome P450 316a1 (EC 1.14.-.-) (CYPCCCXVIA1)| Length = 478 Score = 55.8 bits (133), Expect = 1e-07 Identities = 47/146 (32%), Positives = 70/146 (47%) Frame = -1 Query: 575 LNKLKEMTMVLFETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWG 396 L KL + VL ET+RLY P + + R+ D + +LP G I I + + R+ EV Sbjct: 342 LEKLNYLDAVLHETMRLYPPQVIVGRQLKKDFPYNA-ELPCGSEIYINLYELQRN-EVRY 399 Query: 395 DDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 216 A+ F RF + P LL++S+GPR C + FSM K+ LA +L F Sbjct: 400 PKANHFDAQRFLDS-------PPELLSYSLGPRCCPARKFSMQLLKTLLAPILANFEVLP 452 Query: 215 SPDYVHAPVDIFTLKPKFGLQVFVRP 138 D V + + L G Q+ ++P Sbjct: 453 YGDEVRLDLRL-VLGSSNGFQLALKP 477
>C71D7_SOLCH (P93531) Cytochrome P450 71D7 (EC 1.14.-.-)| Length = 500 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 1/125 (0%) Frame = -1 Query: 587 DPNALNKLKEMTMVLFETLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRD 411 D N + +LK + +V+ ET+RL++P L + R+ + + +P +++ + + RD Sbjct: 343 DENDVEELKYLKLVIKETMRLHAPVPLLVPRECREETEINGYTIPVKTKVMVNVWALGRD 402 Query: 410 KEVWGDDADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQK 231 + W DDA+ FKP RF+ L F G R C G +F + LA +L Sbjct: 403 PKYW-DDAESFKPERFEQCSIDFIGNNFEYLPFGGGRRICPGISFGLANVYLPLAQLLYH 461 Query: 230 FSFTL 216 F + L Sbjct: 462 FDWKL 466
>C12A2_MUSDO (O18635) Cytochrome P450 CYP12A2 (EC 1.14.-.-) (CYPXIIA2)| Length = 537 Score = 55.8 bits (133), Expect = 1e-07 Identities = 42/162 (25%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Frame = -1 Query: 674 GQCICSAYTPEWQERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETLRLYSPALFMQ 501 G +C A PE Q++LR+E+++ + + N + + + E+LR+Y + Sbjct: 344 GLLLCLAKNPEKQKKLREEIMQLLPQKDSEFNEAVFKNMPYLRACIKESLRVYPLTVGNA 403 Query: 500 RKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP---LRFKNGITGAAKVP 330 R D+ + ++PKG I + + +D + A EF P LR +A+ P Sbjct: 404 RTQANDVVISGYRVPKGTLISMNSVTLIKD-DAHYPRASEFLPERWLRASKENEKSAECP 462 Query: 329 HGL--------LAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 228 H L L F G RSCIG+ + +E + +A +++ F Sbjct: 463 HALKASSPFVYLPFGFGSRSCIGRRIAEMELELGIARLIRNF 504 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 101,576,310 Number of Sequences: 219361 Number of extensions: 2120385 Number of successful extensions: 5678 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5121 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5288 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6769072002 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
