>IF5_PHAVU (P48724) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 443

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 20/57 (35%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
 Frame = -2

Query: 391 CYEDAKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFV-KALEPFVKWL 224
           C  ++  +K    ++++LYD DVL E+ I+LW++KG     + S + K  +PF+ WL
Sbjct: 377 CKPNSNALKEVALVLKTLYDADVLEEEAIVLWYQKGLKGDNKNSKIWKNAQPFIDWL 433

>IF5Z_ARATH (Q9S825) Probable eukaryotic translation initiation factor 5-2|
           (eIF-5 2)
          Length = 437

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 22/70 (31%), Positives = 43/70 (61%), Gaps = 3/70 (4%)
 Frame = -2

Query: 424 ELELIYKVQTQCYEDA--KLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFV- 254
           ++ L+  + T C ++   + +K    ++++LYDQD++ E+ +L W+ KG     + S V 
Sbjct: 357 QMHLLNSIGTFCGKNGNEEALKEVALVLKALYDQDIIEEEVVLDWYEKGLTGADKSSPVW 416

Query: 253 KALEPFVKWL 224
           K ++PFV+WL
Sbjct: 417 KNVKPFVEWL 426

>IF5_HUMAN (P55010) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 431

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
 Frame = -2

Query: 379 AKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 224
           A+L+   P I++ +YD D+L E+ I+ W  K S +   +   K +    EPF+KWL
Sbjct: 327 AQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWL 382

>IF5_RAT (Q07205) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 429

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
 Frame = -2

Query: 379 AKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 224
           A+L+   P I++ +YD D+L E+ I+ W  K S +   +   K +    EPF+KWL
Sbjct: 325 AQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWL 380

>IF5_MOUSE (P59325) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 429

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
 Frame = -2

Query: 379 AKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 224
           A+L+   P I++ +YD D+L E+ I+ W  K S +   +   K +    EPF+KWL
Sbjct: 325 AQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWL 380

>IF5_CAEEL (Q22918) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 436

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 4/57 (7%)
 Frame = -2

Query: 382 DAKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKAL----EPFVKWL 224
           +A+L+     II+SLYD+DV  ED+++ W  K S++   +SF K +    +P + WL
Sbjct: 313 EAELLSKSAHIIKSLYDEDVCEEDSLISWGEKPSSKYVSKSFAKKIIENSQPVLNWL 369

>IF5Y_ARATH (Q9C8F1) Probable eukaryotic translation initiation factor 5-1|
           (eIF-5 1)
          Length = 439

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 21/68 (30%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
 Frame = -2

Query: 424 ELELIYKVQTQCYE-DAKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKA 248
           ++ L+  +++ C +  A+  K    +I+ LYD+D+L ED I+ W+ KG         +K 
Sbjct: 365 QMGLLNGIESFCMKASAEAAKEVALVIKGLYDEDILDEDVIVEWYNKGVKS---SPVLKN 421

Query: 247 LEPFVKWL 224
           + PF++WL
Sbjct: 422 VTPFIEWL 429

>IF5_MAIZE (P55876) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 451

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 18/49 (36%), Positives = 29/49 (59%)
 Frame = -2

Query: 370 MKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPFVKWL 224
           +K  P ++++LYD D+L E+TI+ W+            VK  +PFV+WL
Sbjct: 391 LKEVPVVLKALYDGDILDEETIVDWYNDAVAAGKDSQVVKNAKPFVEWL 439

>EI2BE_RABIT (P47823) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor)
          Length = 721

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
 Frame = -2

Query: 568 EVVRMLWDVLME-AVQWSGKNQQQNSNSALRQ--VNAWAGLMNAFCTSGKLELELIYKVQ 398
           EV+++L  V++E  +Q      + N   AL    + AW+ +   +       LE +  ++
Sbjct: 591 EVMQVLSHVVLEFPLQQMDSPLEANRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIE 650

Query: 397 TQCYEDAKLMKLFPEIIRSLYDQDVLAEDTILLWF-RKGSNQKGRQ-SFVKALEPFVKWL 224
               E   L     +++   Y  ++LAE+TIL WF ++    KGRQ    + L+ F++WL
Sbjct: 651 EFFLEHEALGTCIAKVLMGFYQLEILAEETILSWFGQRDVTDKGRQLRKNQQLQRFIQWL 710

>EI2BE_RAT (Q64350) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor)
          Length = 716

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
 Frame = -2

Query: 475 VNAWAGLMNAFCTSGKLELELIYKVQTQCYEDAKLMKLFPEIIRSLYDQDVLAEDTILLW 296
           + AW+ +   +       LE +  ++    E   L+    +++ + Y  ++LAE+TIL W
Sbjct: 620 LKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVPSLAKVLMAFYQLEILAEETILSW 679

Query: 295 F-RKGSNQKGRQ-SFVKALEPFVKWL 224
           F ++    KG+Q    + L+ F++WL
Sbjct: 680 FSQRDITDKGQQLRKNQQLQRFIQWL 705

>IF4G1_HUMAN (Q04637) Eukaryotic translation initiation factor 4 gamma 1|
            (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220)
          Length = 1600

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 2/108 (1%)
 Frame = -2

Query: 541  LMEAVQWSGKNQQQNSNSALRQVNAWAGLMNAFCTSGKLELELIYKVQTQCYEDAKLMKL 362
            LM AV +S    +      +  + A A L+  +    + EL+ +Y +Q       +   L
Sbjct: 1483 LMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNL 1542

Query: 361  FPEIIRSLYDQDVLAEDTILLW--FRKGSNQKGRQSFVKALEPFVKWL 224
                  +LYD+DV+ ED    W   +  + Q+G+   +K++  F KWL
Sbjct: 1543 LRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWL 1590

>EI2BE_HUMAN (Q13144) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor)
          Length = 721

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
 Frame = -2

Query: 475 VNAWAGLMNAFCTSGKLELELIYKVQTQCYEDAKLMKLFPEIIRSLYDQDVLAEDTILLW 296
           + AW+ +   +       LE +  ++    E   L     +++ + Y  ++LAE+TIL W
Sbjct: 625 LKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSW 684

Query: 295 F-RKGSNQKGRQ-SFVKALEPFVKWL 224
           F ++ +  KG+Q    + L+ F++WL
Sbjct: 685 FSQRDTTDKGQQLRKNQQLQRFIQWL 710

>IF4G1_MOUSE (Q6NZJ6) Eukaryotic translation initiation factor 4 gamma 1|
            (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1)
          Length = 1600

 Score = 37.0 bits (84), Expect = 0.057
 Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
 Frame = -2

Query: 463  AGLMNAFCTSGKLELELIYKVQTQCY---EDAKLMKLFPEIIRSLYDQDVLAEDTILLW- 296
            A L+  +    + EL+ +Y +Q       + A L+++F +   +LYD+DV+ ED    W 
Sbjct: 1508 ARLLQKYLCDEQKELQALYALQALVVTLEQPANLLRMFFD---ALYDEDVVKEDAFYSWE 1564

Query: 295  -FRKGSNQKGRQSFVKALEPFVKWL 224
              +  + Q+G+   +K++  F  WL
Sbjct: 1565 SSKDPAEQQGKGVALKSVTAFFNWL 1589

>IF5_YEAST (P38431) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 405

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 17/58 (29%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
 Frame = -2

Query: 385 EDAKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSN----QKGRQSFVKALEPFVKWL 224
           E   L+ L P+I+  LY+ D+++E+ I+ +  K S     ++  +   +A +PF+ WL
Sbjct: 335 EHKDLIPLLPKILVQLYNNDIISEEEIMRFGTKSSKKFVPKEVSKKVRRAAKPFITWL 392

>IF4G3_HUMAN (O43432) Eukaryotic translation initiation factor 4 gamma 3|
            (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II)
            (eIF4GII)
          Length = 1585

 Score = 33.9 bits (76), Expect = 0.48
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
 Frame = -2

Query: 424  ELELIYKVQTQCY---EDAKLMKLFPEIIRSLYDQDVLAEDTILLW--FRKGSNQKGRQS 260
            EL+ +Y +Q       + A L+++F +    LYD++V++ED    W   +  + Q G+  
Sbjct: 1507 ELQALYALQASIVKLDQPANLLRMFFDC---LYDEEVISEDAFYKWESSKDPAEQNGKGV 1563

Query: 259  FVKALEPFVKWL 224
             +K++  F  WL
Sbjct: 1564 ALKSVTAFFTWL 1575

>EI2BE_CANAL (P87163) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor) (Guanine nucleotide
           exchange factor subunit GCD6) (GCD complex subunit GCD6)
           (Fragment)
          Length = 189

 Score = 33.5 bits (75), Expect = 0.63
 Identities = 15/42 (35%), Positives = 23/42 (54%)
 Frame = -2

Query: 349 IRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPFVKWL 224
           ++S YD +V+ E+ IL W+  G N + R    K    F+ WL
Sbjct: 136 VKSFYDMEVVEEENILKWWNDGENDEVRTLAAK----FITWL 173

>IF4G3_MOUSE (Q80XI3) Eukaryotic translation initiation factor 4 gamma 3|
            (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II)
            (eIF4GII)
          Length = 1579

 Score = 33.5 bits (75), Expect = 0.63
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 5/72 (6%)
 Frame = -2

Query: 424  ELELIYKVQTQCY---EDAKLMKLFPEIIRSLYDQDVLAEDTILLW--FRKGSNQKGRQS 260
            EL+ +Y +Q       + A L+++F +    LYD++V++ED    W   +  + Q G+  
Sbjct: 1501 ELQALYALQASIVKLDQPANLLRMFFDC---LYDEEVISEDAFYKWESSKDPAEQAGKGV 1557

Query: 259  FVKALEPFVKWL 224
             +K++  F  WL
Sbjct: 1558 ALKSVTAFFTWL 1569

>IF4G1_RABIT (P41110) Eukaryotic translation initiation factor 4 gamma 1|
            (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220)
          Length = 1402

 Score = 33.1 bits (74), Expect = 0.82
 Identities = 17/56 (30%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
 Frame = -2

Query: 385  EDAKLMKLFPEIIRSLYDQDVLAEDTILLW--FRKGSNQKGRQSFVKALEPFVKWL 224
            + A L+++F +   +LYD+DV+ E+    W   +  + Q+G+   +K++  F KWL
Sbjct: 1339 QPANLLRMFFD---ALYDEDVVKEEAFYSWESSKDPAEQQGKGVALKSVTAFFKWL 1391

>EI2BE_YEAST (P32501) Translation initiation factor eIF-2B epsilon subunit|
           (eIF-2B GDP-GTP exchange factor) (Guanine nucleotide
           exchange factor subunit GCD6) (GCD complex subunit GCD6)
          Length = 712

 Score = 32.7 bits (73), Expect = 1.1
 Identities = 19/64 (29%), Positives = 32/64 (50%)
 Frame = -2

Query: 415 LIYKVQTQCYEDAKLMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALEPF 236
           ++ K+  Q ++   L+ LF  ++ SLYD D++ ED I  W+   S         K    +
Sbjct: 639 IMEKIVEQSFDKPDLI-LFSALV-SLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLTVKW 696

Query: 235 VKWL 224
           V+WL
Sbjct: 697 VEWL 700

>TALA_POVJC (P03072) Large T antigen|
          Length = 688

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 13/29 (44%), Positives = 17/29 (58%)
 Frame = -3

Query: 147 GGGGHNILFFTCEHCCHXAVVLRHYCTRI 61
           G GGHNILFF   H  H    + +YC ++
Sbjct: 189 GFGGHNILFFLTPH-RHRVSAINNYCQKL 216

>IF5_DROME (Q9VXK6) Eukaryotic translation initiation factor 5 (eIF-5)|
          Length = 464

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 4/54 (7%)
 Frame = -2

Query: 373 LMKLFPEIIRSLYDQDVLAEDTILLWFRKGSNQKGRQSFVKALE----PFVKWL 224
           LM     I +  YD D+L E  IL W +K S +   ++    +     PFV WL
Sbjct: 352 LMSKVAGIFKLFYDLDILDEAVILEWAQKVSKRHVSKNIAAEIHEKAMPFVLWL 405


  Database: uniprot_sprot.fasta
    Posted date:  May 25, 2006  5:36 PM
  Number of letters in database: 80,573,946
  Number of sequences in database:  219,361
  
Lambda     K      H
   0.318    0.135    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,149,824
Number of Sequences: 219361
Number of extensions: 1669816
Number of successful extensions: 3710
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3631
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3709
length of database: 80,573,946
effective HSP length: 108
effective length of database: 56,882,958
effective search space used: 6882837918
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)