ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal6c01 |
|---|---|
| Clone Library Name | barley_pub |
>C72A1_CATRO (Q05047) Cytochrome P450 72A1 (EC 1.3.3.9) (CYPLXXII) (Secologanin| synthase) (SLS) Length = 524 Score = 193 bits (491), Expect = 4e-49 Identities = 89/191 (46%), Positives = 129/191 (67%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G E T +LLTW+ LLS +PEWQER R+EVL+ FG P+ LN LK ++M+L+E LRL Sbjct: 333 GQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLRL 392 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 Y P + + + D +GS +P G +++P ++HR+K +WG+DA EF P+RF +G+ Sbjct: 393 YPPVIDLTKIVHKDTKLGSYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFVDGVAN 452 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPK 164 A K L FS GPR C+GQNF++L+AK LA++LQ+F F ++P YVHAP I T++P+ Sbjct: 453 ATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQ 512 Query: 163 FGLQVFVRPLD 131 FG V + L+ Sbjct: 513 FGSHVIYKKLE 523
>CP4B1_RAT (P15129) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) (P450 L-2) Length = 510 Score = 111 bits (278), Expect = 2e-24 Identities = 70/192 (36%), Positives = 104/192 (54%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W +Y +++YPE Q+ R+EV G Q S + L K+ +TM + E R Sbjct: 315 GHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDSFQWDDLAKMTYLTMCMKECFR 374 Query: 526 LYSPALFMQRKTVADMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ +T V LP G I + I +HR+ VW D + F PLRF Sbjct: 375 LYPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVW-PDPEVFDPLRFSPE- 432 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 A + P + FS GPR+CIGQ F+M E K AL L +F F+L P + V L+ Sbjct: 433 NAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQLILR 492 Query: 169 PKFGLQVFVRPL 134 K G+ ++++PL Sbjct: 493 SKNGIHLYLKPL 504
>CP4B1_RABIT (P15128) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-isozyme| 5) Length = 506 Score = 111 bits (278), Expect = 2e-24 Identities = 67/192 (34%), Positives = 107/192 (55%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W +Y +++YPE Q+R R+EV + G Q S L K+ +TM + E R Sbjct: 311 GHDTTTSGISWFLYCMALYPEHQQRCREEVREILGDQDSFQWEDLAKMTYLTMCMKECFR 370 Query: 526 LYSPALFMQRKTVADMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ ++ V LP G I + I +HR+ +VW D + F PLRF Sbjct: 371 LYPPVPQVYRQLSKPVSFVDGRSLPAGSLISLHIYALHRNSDVW-PDPEVFDPLRFSPE- 428 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + + P+ + FS GPR+CIGQ F+M E K AL L +F F++ P + + L+ Sbjct: 429 NSSGRHPYAFIPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSVDPLRLPIKLPQLVLR 488 Query: 169 PKFGLQVFVRPL 134 K G+ ++++PL Sbjct: 489 SKNGIHLYLKPL 500
>CP4B1_MOUSE (Q64462) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)| Length = 511 Score = 108 bits (269), Expect = 2e-23 Identities = 68/193 (35%), Positives = 105/193 (54%), Gaps = 3/193 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG-MQSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W +Y +++YP Q+R R+EV + G S + L ++ +TM + E R Sbjct: 316 GHDTTTSGISWFLYCMALYPMHQQRCREEVREILGDRDSFQWDDLAQMTYLTMCMKECFR 375 Query: 526 LYSPALFMQRKTVADMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK-NG 353 LY P + R+ +T V LP G I + I +HR+ VW D + F PLRF Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVW-PDPEVFDPLRFSPEN 434 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 +TG + P + FS GPR+CIGQ F+M E K AL L +F F+ P + V L Sbjct: 435 MTG--RHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIKVPQLIL 492 Query: 172 KPKFGLQVFVRPL 134 + K G+ ++++PL Sbjct: 493 RSKNGIHLYLKPL 505
>CP4B1_HUMAN (P13584) Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1) (P450-HP)| Length = 511 Score = 107 bits (267), Expect = 4e-23 Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 GH+ T+ ++W +Y +++YPE Q R R+EV + G Q + L K+ +TM + E+ R Sbjct: 316 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375 Query: 526 LYSPALFMQRKTVADMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ +T V LP G I + I +HR+ VW D + F LRF Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVW-PDPEVFDSLRFSTE- 433 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + + P + FS GPR+CIGQ F+M E K A+ L +F F+L P + + L+ Sbjct: 434 NASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLR 493 Query: 169 PKFGLQVFVRPL 134 K G + ++PL Sbjct: 494 SKNGFHLHLKPL 505
>C13A7_CAEEL (Q27519) Putative cytochrome P450 CYP13A7 (EC 1.14.-.-)| Length = 518 Score = 107 bits (266), Expect = 5e-23 Identities = 66/173 (38%), Positives = 101/173 (58%), Gaps = 5/173 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP----NALNKLKEMTMVLFE 536 G++ T+L L++S YLL+ +PE Q++L++EV +E PDP + L+KLK + V+ E Sbjct: 327 GYDTTALSLSYSSYLLATHPEIQKKLQEEVDRE----CPDPEVTFDQLSKLKYLECVVKE 382 Query: 535 TLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK 359 LRLY A L RK + V +++ G I + +H D +VWGDD +EFKP R++ Sbjct: 383 ALRLYPLASLVHNRKCLKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWE 442 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYV 200 +G G L F MGPR CIG +M+E K L +L+ ++F +P+ V Sbjct: 443 SG-DELFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLTNILKNYTFETTPETV 494
>C13A4_CAEEL (Q27513) Putative cytochrome P450 CYP13A4 (EC 1.14.-.-)| Length = 520 Score = 106 bits (265), Expect = 6e-23 Identities = 65/171 (38%), Positives = 100/171 (58%), Gaps = 5/171 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP----NALNKLKEMTMVLFE 536 G++ T+L L++S YLL+ +PE Q++L++EV +E PDP + ++KLK M V+ E Sbjct: 327 GYDTTALSLSYSSYLLATHPEIQKKLQEEVDRE----CPDPEVTFDQISKLKYMECVVKE 382 Query: 535 TLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK 359 LR+Y A L RK + V +++ +G + + +H D +VWGDDA EFKP R++ Sbjct: 383 ALRMYPLASLVHNRKCMKKTNVLGVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWE 442 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 G G L F MGPR CIG +M+E K L +L+K++F S + Sbjct: 443 TG-DELFYAKGGYLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFDTSTE 492
>CP3AT_PIG (P79401) Cytochrome P450 3A29 (EC 1.14.14.1) (CYPIIIA29)| Length = 503 Score = 106 bits (265), Expect = 6e-23 Identities = 57/162 (35%), Positives = 97/162 (59%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L+ Y L+ +P+ Q++L++E+ F ++P +AL +++ + MV+ ETLR Sbjct: 306 GYETTSSALSLLAYELATHPDVQQKLQEEIEATFPNKAPPTYDALAQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R D+ + + +PKG +V+P+ ++HRD ++W + +EF+P RF Sbjct: 366 LYPIAARLERACKKDVEIHGVFVPKGTVVVVPVFVLHRDPDLW-PEPEEFRPERFSKKHK 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 P+ L F GPR+CIG F+++ K L +LQ FSF Sbjct: 425 DTIN-PYTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFSF 465
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cytochrome| P450(BM-3)) (P450BM-3) [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1048 Score = 106 bits (264), Expect = 8e-23 Identities = 67/184 (36%), Positives = 98/184 (53%), Gaps = 4/184 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE TS LL++++Y L P ++ +E + P + +LK + MVL E LRL Sbjct: 265 GHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRL 324 Query: 523 YSPA----LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 + A L+ + TV G L KG +++ IP +HRDK +WGDD +EF+P RF+N Sbjct: 325 WPTAPAFSLYAKEDTVLG---GEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFEN 381 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 +A H F G R+CIGQ F++ EA L +ML+ F F +Y + T Sbjct: 382 ---PSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLT 438 Query: 175 LKPK 164 LKP+ Sbjct: 439 LKPE 442
>C13A1_CAEEL (Q27520) Putative cytochrome P450 CYP13A1 (EC 1.14.-.-)| Length = 519 Score = 106 bits (264), Expect = 8e-23 Identities = 57/162 (35%), Positives = 93/162 (57%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G + T+L L+++ YLL+ +PE Q++L++EV +E + L+KLK M V E LRL Sbjct: 327 GFDTTALSLSYATYLLATHPEIQKKLQEEVNRECPNPEVTIDQLSKLKYMECVFKEALRL 386 Query: 523 YSPALFMQ-RKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 Y F R+ + + +G++K+ G I + +H D +WGDDA++FKP R++ + Sbjct: 387 YPLGAFANSRRCMRNTKLGNMKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNS 446 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G + F +GPR CIG + +E K L +L+KF+F Sbjct: 447 DQIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTF 488
>CP3AO_SHEEP (Q29496) Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24)| Length = 503 Score = 105 bits (263), Expect = 1e-22 Identities = 54/162 (33%), Positives = 100/162 (61%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++ +Y+L+ +P+ Q++L++E+ F ++P + L +++ + MV+ ETLR Sbjct: 306 GYETTSNTLSFLLYILATHPDVQQKLQEEIDATFPNKAPPTYDVLAQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 ++ A+ + R D+ + + +PKG A+ +PI ++HRD ++W + +EF+P RF Sbjct: 366 MFPIAVRLDRLCKKDVEIHGVSIPKGTAVTVPIFVLHRDPQLW-PEPEEFRPERFSKKNK 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + P+ L F GPR+CIG F+++ K + +LQ FSF Sbjct: 425 DSIN-PYVYLPFGTGPRNCIGMRFAIMNMKLAIVRVLQNFSF 465
>CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450 reductase 2| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1054 Score = 104 bits (260), Expect = 2e-22 Identities = 65/194 (33%), Positives = 104/194 (53%), Gaps = 5/194 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE TS LL++++Y L +PE ++ ++E + +P+ + +LK + MVL ETLRL Sbjct: 268 GHETTSGLLSFAIYCLLTHPEKLKKAQEEADRVLTDDTPEYKQIQQLKYIRMVLNETLRL 327 Query: 523 YSPA----LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 Y A L+ + TV G + KG + + IP +HRD+ WG DA++F+P RF++ Sbjct: 328 YPTAPAFSLYAKEDTVLG---GEYPISKGQPVTVLIPKLHRDQNAWGPDAEDFRPERFED 384 Query: 355 GITGAAKVP-HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIF 179 + +P H F G R+CIG F++ EA L L+L+ F Y + Sbjct: 385 ----PSSIPHHAYKPFGNGQRACIGMQFALQEATMVLGLVLKHFELINHTGYELKIKEAL 440 Query: 178 TLKPKFGLQVFVRP 137 T+KP ++ V+P Sbjct: 441 TIKPD-DFKITVKP 453
>C13A5_CAEEL (Q27514) Putative cytochrome P450 CYP13A5 (EC 1.14.-.-)| Length = 520 Score = 104 bits (260), Expect = 2e-22 Identities = 60/165 (36%), Positives = 99/165 (60%), Gaps = 1/165 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G++ T+L L++S YLL+ +PE Q++L++EV +E + ++KLK M V+ E LR+ Sbjct: 327 GYDTTALSLSYSSYLLARHPEIQKKLQEEVDRECPNPEVTFDQISKLKYMECVVKEALRM 386 Query: 523 YSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 Y A + RK + + V +++ KG + + +H D +VWG+DA+EF+P R+++G Sbjct: 387 YPLASIVHNRKCMKETNVLGVQIEKGTNVQVDTWTLHYDPKVWGEDANEFRPERWESG-D 445 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 212 G L F MGPR CIG +M+E K L +L+K++F S Sbjct: 446 ELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFETS 490
>CP4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (CYPIVS3)| Length = 495 Score = 104 bits (259), Expect = 3e-22 Identities = 64/192 (33%), Positives = 103/192 (53%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GH+ TS + +++ LLS P+ Q+R +E + G + + + V+ ETLR+ Sbjct: 308 GHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEGREK------ESMPYLEAVIKETLRI 361 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 Y F RK + D+ VG L +PKG +I I ++HRD + + D + F P RF + Sbjct: 362 YPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL--VNE 418 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPK 164 P AFS GPR+CIGQ F+MLE K++LA++L+ + F D+ P+ K Sbjct: 419 KQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLAELVTKSG 478 Query: 163 FGLQVFVRPLDK 128 G+++ + P D+ Sbjct: 479 NGIRLRILPRDE 490
>CP132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 103 bits (258), Expect = 4e-22 Identities = 63/188 (33%), Positives = 97/188 (51%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE T+ ++W YL+++ P+ ++ + E+ GM+ P + L KL T L E+ R Sbjct: 275 GHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRY 334 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 +S + R+ V D + ++ +G +VIPI +H D W D D F P RF T Sbjct: 335 FSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTD 393 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPK 164 + + L F G R CIGQ+F+++E A+M Q F+F L+P Y TL+PK Sbjct: 394 RPRCAY--LPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPK 451 Query: 163 FGLQVFVR 140 G+ V R Sbjct: 452 HGVHVIGR 459
>CP132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)| Length = 461 Score = 103 bits (258), Expect = 4e-22 Identities = 63/188 (33%), Positives = 97/188 (51%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE T+ ++W YL+++ P+ ++ + E+ GM+ P + L KL T L E+ R Sbjct: 275 GHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRY 334 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 +S + R+ V D + ++ +G +VIPI +H D W D D F P RF T Sbjct: 335 FSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPR-WWPDPDRFDPGRFLRCPTD 393 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPK 164 + + L F G R CIGQ+F+++E A+M Q F+F L+P Y TL+PK Sbjct: 394 RPRCAY--LPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPK 451 Query: 163 FGLQVFVR 140 G+ V R Sbjct: 452 HGVHVIGR 459
>C13A3_CAEEL (Q27517) Putative cytochrome P450 CYP13A3 (EC 1.14.-.-)| Length = 520 Score = 103 bits (258), Expect = 4e-22 Identities = 66/179 (36%), Positives = 105/179 (58%), Gaps = 5/179 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP----NALNKLKEMTMVLFE 536 G++ T+L L++S YLL+ +PE Q++L++EV +E PDP + L+KLK M V+ E Sbjct: 327 GYDTTALSLSYSSYLLARHPEIQKKLQEEVDRE----CPDPEVTFDQLSKLKYMECVIKE 382 Query: 535 TLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK 359 TLRLY A + RK + TV +K+ +G + +H D + WG++A+EFKP R++ Sbjct: 383 TLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWE 442 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 +G A L F +GPR CIG + +E K LA +L+K+S + + H P+ + Sbjct: 443 SG-DEQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETTFE-THIPLKL 499
>CP3AG_MOUSE (Q64481) Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16)| Length = 504 Score = 103 bits (257), Expect = 5e-22 Identities = 56/162 (34%), Positives = 97/162 (59%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS +L+++VY L+ +P+ Q++L++E+ + ++P + + ++ + MVL ETLR Sbjct: 307 GYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLDMVLNETLR 366 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY +QR D+ + + +PKG ++IP ++H D + W + +EF+P RF Sbjct: 367 LYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHW-PEPEEFQPERFSKENK 425 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G+ P+ L F GPR+CIG F+++ K L +LQ FSF Sbjct: 426 GSID-PYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSF 466
>CP4FC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)| Length = 524 Score = 103 bits (257), Expect = 5e-22 Identities = 71/196 (36%), Positives = 110/196 (56%), Gaps = 5/196 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV LK+ + + + L +L +TM + E+ Sbjct: 329 GHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LRL+ PA F+ R D+ + + +PKGI +I I +H + VW D + + P RF + Sbjct: 389 LRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFRF-D 446 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI-F 179 + P + FS GPR+CIGQ F+M E K LALML F F PD+ + Sbjct: 447 PENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFL--PDHTEPRRKLEL 504 Query: 178 TLKPKFGLQVFVRPLD 131 ++ + GL + V PL+ Sbjct: 505 IMRAEGGLWLRVEPLN 520
>CP3AC_CANFA (P24463) Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12)| (P450-PBD-1) Length = 503 Score = 103 bits (256), Expect = 7e-22 Identities = 57/162 (35%), Positives = 98/162 (60%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G+E TS L++ +Y L+ +P+ Q++L++E+ F ++ P +AL +++ + MVL ETLR Sbjct: 306 GYETTSTSLSFLMYELATHPDVQQKLQEEIDATFPNKALPTYDALVQMEYLDMVLNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R D+ + + +PKG +++P +HRD+ +W + +EF+P RF Sbjct: 366 LYPIAGRLERVCKKDVEISGVFIPKGTVVMVPTFTLHRDQSLW-PEPEEFRPERFSRKNK 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + P+ L F GPR+CIG F+++ K L +LQ FSF Sbjct: 425 DSIN-PYTYLPFGTGPRNCIGMRFAIMNMKLALVRVLQNFSF 465
>CP4Z1_HUMAN (Q86W10) Cytochrome P450 4Z1 (EC 1.14.14.1) (CYPIVZ1)| Length = 505 Score = 102 bits (255), Expect = 9e-22 Identities = 68/193 (35%), Positives = 104/193 (53%), Gaps = 5/193 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 GH+ TS ++W +Y L+ YPE Q+R R E+ + G S L+++ TM + E LR Sbjct: 315 GHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLR 374 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY+P + + R +T LP GI + I I +H + W +D F PLRF Sbjct: 375 LYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFSR-- 431 Query: 349 TGAAKV-PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI--F 179 + K+ P+ + FS G R+CIGQ+F+++E K +AL L +F L+PD+ P + Sbjct: 432 ENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFK--LAPDHSRPPQPVRQV 489 Query: 178 TLKPKFGLQVFVR 140 LK K G+ VF + Sbjct: 490 VLKSKNGIHVFAK 502
>C13A6_CAEEL (Q27515) Putative cytochrome P450 CYP13A6 (EC 1.14.-.-)| Length = 518 Score = 102 bits (254), Expect = 1e-21 Identities = 62/188 (32%), Positives = 103/188 (54%), Gaps = 8/188 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFE 536 G + T+L L+++ YLL+ +PE Q +L++EV +E PDP L+KLK + V+ E Sbjct: 325 GFDTTALSLSYATYLLATHPEIQTKLQEEVDRE----CPDPEIFFDHLSKLKYLECVMKE 380 Query: 535 TLRLYSPALFMQ-RKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK 359 TLRLY RK + + T+ + +G+ I + +H + +WG+D ++FKP R++ Sbjct: 381 TLRLYPLGTTANTRKCMRETTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWE 440 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI- 182 NG + + F GPR CIG + +E K LA +L+++SF + + PV + Sbjct: 441 NGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFRTTKN-TQIPVKLV 499 Query: 181 --FTLKPK 164 TL P+ Sbjct: 500 GKLTLSPE 507
>CP3AJ_CAPAE (P79152) Cytochrome P450 3A19 (EC 1.14.14.1) (CYPIIIA19) (Fragment)| Length = 218 Score = 102 bits (253), Expect = 1e-21 Identities = 55/166 (33%), Positives = 101/166 (60%), Gaps = 5/166 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++ +Y L+ +P+ Q++L++E+ F ++P +AL +++ + MV+ ETLR Sbjct: 17 GYETTSTSLSFIIYELATHPDVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLR 76 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 ++ A ++R D+ + + +PKG +++P+ ++H + E W + +EF+P RF K Sbjct: 77 MFPIAGRLERLCKKDVEIHGVSIPKGTTVMVPLFVLHNNPEFW-PEPEEFRPERFSKKNK 135 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 +GI P+ L F GPR+C+G F+++ K L +LQ FSF Sbjct: 136 DGIN-----PYVYLPFGTGPRNCVGMRFALMNIKLALVRILQNFSF 176
>CP4AB_HUMAN (Q02928) Cytochrome P450 4A11 precursor (EC 1.14.15.3) (CYPIVA11)| (Fatty acid omega-hydroxylase) (P-450 HK omega) (Lauric acid omega-hydroxylase) (CYP4AII) (P450-HL-omega) Length = 519 Score = 101 bits (252), Expect = 2e-21 Identities = 66/192 (34%), Positives = 102/192 (53%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W +Y L+ +P+ QER R+E+ G S N L+++ TM + E LR Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ +T LPKGI +++ I +H + +VW + + F P RF Sbjct: 382 LYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFA--- 437 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 G+A+ H L FS G R+CIG+ F+M E K AL L +F P + P+ LK Sbjct: 438 PGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLK 497 Query: 169 PKFGLQVFVRPL 134 K G+ + +R L Sbjct: 498 SKNGIHLRLRRL 509
>CP4AC_MOUSE (Q91WL5) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12)| Length = 508 Score = 101 bits (251), Expect = 3e-21 Identities = 65/192 (33%), Positives = 100/192 (52%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ PE Q+R RKE+ G S N L+K+ TM + E LR Sbjct: 320 GHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGDGTSITWNDLDKMPYTTMCIKEALR 379 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 +Y P + R+ + +T LPKGI +++ +H + VW + + F P RF Sbjct: 380 IYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFA--- 435 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 G+++ H L FS G R+CIG+ F+M E K +AL L +F P V P+ LK Sbjct: 436 PGSSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVLK 495 Query: 169 PKFGLQVFVRPL 134 K G+ + ++ L Sbjct: 496 SKNGIHLHLKKL 507
>CP4A7_RABIT (P14581) Cytochrome P450 4A7 precursor (EC 1.14.15.3) (CYPIVA7)| (Lauric acid omega-hydroxylase) (P450-KA-2) Length = 511 Score = 100 bits (249), Expect = 4e-21 Identities = 68/192 (35%), Positives = 99/192 (51%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +PE Q R R+E+ G S L+K+ TM + E LR Sbjct: 323 GHDTTASGISWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDKMPYTTMCIKEALR 382 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + K + +T LPKGI I + I +H + +VW + + F P RF Sbjct: 383 LYPPVPGVGSKLSSPVTFPDGRSLPKGIIITLSIYGLHHNPKVW-PNPEVFDPSRFA--- 438 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 G+A+ H L FS G R+CIG+ F+M E K +AL L +F P V P+ LK Sbjct: 439 PGSARHSHAFLPFSGGSRNCIGKQFAMNELKVAVALTLVRFELLPDPTRVPIPITRLVLK 498 Query: 169 PKFGLQVFVRPL 134 K G+ + +R L Sbjct: 499 SKNGIHLRLRKL 510
>C13A2_CAEEL (Q27518) Putative cytochrome P450 CYP13A2 (EC 1.14.-.-)| Length = 515 Score = 100 bits (249), Expect = 4e-21 Identities = 56/162 (34%), Positives = 91/162 (56%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G + T+L L++ YLL++ P+ QE++ +E+ +EFG + L +LK M V+ E LRL Sbjct: 324 GFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGTSEVEFEKLGRLKYMDCVIKEALRL 383 Query: 523 YSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 Y A + RK + TV +K+ G+ + + +H D E+WG+D EFKP R+ Sbjct: 384 YPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKPERWSTDEP 443 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 K + L F +GPR CIG +++E K L +L+ ++F Sbjct: 444 LEHKGAY--LPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTF 483
>C13AA_CAEEL (Q09653) Putative cytochrome P450 CYP13A10 (EC 1.14.-.-)| Length = 519 Score = 100 bits (249), Expect = 4e-21 Identities = 53/162 (32%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G + T+L L+++ +LL+ +PE Q++L++E+ +E S + L+KLK M ++ ETLRL Sbjct: 327 GFDTTALSLSYTTFLLATHPEVQKKLQEEIERECIEPSISFDHLSKLKYMDCIIKETLRL 386 Query: 523 YS-PALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 Y + R+ + +G++++ G + + +H D ++WGDDA EFKP R+ + Sbjct: 387 YPLGTMANSRRCMRATKLGNVEVEVGTMVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNC 446 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G ++F +GPR C+G + +E K LA +L+K++F Sbjct: 447 DQVFQKGGYISFGLGPRQCVGMRLAYMEEKMLLAHILRKYTF 488
>CP3AS_BOVIN (P79102) Cytochrome P450 3A28 (EC 1.14.14.1) (CYPIIIA28)| Length = 507 Score = 100 bits (248), Expect = 6e-21 Identities = 52/162 (32%), Positives = 98/162 (60%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++ +Y L+ +P Q++L++E+ F ++P +AL +++ + MV+ ETLR Sbjct: 306 GYETTSSTLSFIIYELTTHPHVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 ++ A ++R D+ + + +PKG +++P+ ++H + E+W + +EF+P RF Sbjct: 366 MFPIAGRLERVCKKDVEIHGVTIPKGTTVLVPLFVLHNNPELW-PEPEEFRPERFSKNNK 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + P+ L F GPR+C+G F+++ K L +LQ FSF Sbjct: 425 DSIN-PYVYLPFGTGPRNCLGMRFAIMNIKLALVRILQNFSF 465
>C13A8_CAEEL (Q27516) Putative cytochrome P450 CYP13A8 (EC 1.14.-.-)| Length = 509 Score = 100 bits (248), Expect = 6e-21 Identities = 56/162 (34%), Positives = 94/162 (58%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G + T++ L++ Y L++ P+ Q +L+ EV KE + L+KLK M V+ E+LRL Sbjct: 321 GFDTTAISLSYVTYFLALNPKIQSKLQDEVDKECPNDEITFDQLSKLKYMDNVIKESLRL 380 Query: 523 YSPALFMQ-RKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 + A F R+ + + +G + G+ ++I +H DK VWG+D +EFKP R+ + +T Sbjct: 381 FPFASFANSRRCMRNTVIGEQIVEAGVDVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLT 440 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 L+F GPR C+G F++LE K L+ +L+K++F Sbjct: 441 ----PQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKKYTF 478
>CP4X1_HUMAN (Q8N118) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 509 Score = 99.8 bits (247), Expect = 7e-21 Identities = 67/195 (34%), Positives = 99/195 (50%), Gaps = 2/195 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 GH+ + ++W +Y L++ PE QER R+EV G S + L ++ TM + ET R Sbjct: 317 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 376 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L + R +T LP GI +V+ I +H + VW + F PLRF Sbjct: 377 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVW-KNPKVFDPLRFSQE- 434 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + P+ L FS G R+CIGQ F+M+E K T+AL+L F T P + F LK Sbjct: 435 NSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILK 494 Query: 169 PKFGLQVFVRPLDKC 125 PK G+ + ++ L +C Sbjct: 495 PKNGMYLHLKKLSEC 509
>CP3AD_MOUSE (Q64464) Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13)| Length = 503 Score = 99.4 bits (246), Expect = 1e-20 Identities = 55/161 (34%), Positives = 96/161 (59%), Gaps = 1/161 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++++YLL+I+P+ Q++L+ E+ ++P + L +++ + MV+ ETLR Sbjct: 306 GYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R D+ + L +PKG ++IP +H+D + W + +EF+P RF Sbjct: 366 LYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYW-PEPEEFRPERFSKKNQ 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 224 + P+ L F GPR+CIG F+++ K L +LQ F+ Sbjct: 425 DSIN-PYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFT 464
>CP3A5_HUMAN (P20815) Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (P450-PCN3)| (HLp2) Length = 502 Score = 98.6 bits (244), Expect = 2e-20 Identities = 56/165 (33%), Positives = 99/165 (60%), Gaps = 4/165 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS +L++++Y L+ +P+ Q++L+KE+ ++P +A+ +++ + MV+ ETLR Sbjct: 306 GYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF---KN 356 L+ A+ ++R D+ + + +PKG +VIP +H D + W + +EF+P RF K+ Sbjct: 366 LFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYW-TEPEEFRPERFSKKKD 424 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 I P+ F GPR+CIG F+++ K L +LQ FSF Sbjct: 425 SID-----PYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSF 464
>CP4X1_RAT (Q8K4D6) Cytochrome P450 4X1 (EC 1.14.14.1) (CYPIVX1)| Length = 507 Score = 98.2 bits (243), Expect = 2e-20 Identities = 65/195 (33%), Positives = 99/195 (50%), Gaps = 2/195 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 GH+ ++ ++W +Y L++ PE Q+R R E+ G S L+++ TM + ETLR Sbjct: 315 GHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGSSITWEQLDEIPYTTMCIKETLR 374 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L P + R+ +T+ LP G+ +V+ I +H + VW D F PLRF Sbjct: 375 LIPPIPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVW-KDPKVFDPLRFTKE- 432 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + P L FS GPR+CIGQ F+MLE K +AL L +F A L+ Sbjct: 433 NSEQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFRVAADLTRPPAFSSHTVLR 492 Query: 169 PKFGLQVFVRPLDKC 125 PK G+ + ++ L +C Sbjct: 493 PKHGIYLHLKKLPEC 507
>CP4C3_DROME (Q9VA27) Cytochrome P450 4c3 (EC 1.14.-.-) (CYPIVC3)| Length = 535 Score = 97.4 bits (241), Expect = 4e-20 Identities = 61/199 (30%), Positives = 104/199 (52%), Gaps = 8/199 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFET 533 GH+ TS ++W+++LL +PE+QER+ +E+ FG P + L +M + + ++ Sbjct: 343 GHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDS 402 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LRL+ M R D+ +G +P G +I +HR+ V+ ++F P F Sbjct: 403 LRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVF-PKPEQFNPDNFLPE 461 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI--- 182 A + P + FS GPR+CIGQ F++LE K+ ++ +L+K+ + V D+ Sbjct: 462 -NCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKI----EAVDRREDLTLL 516 Query: 181 --FTLKPKFGLQVFVRPLD 131 L+PK GL+V + P D Sbjct: 517 GELILRPKDGLRVKITPRD 535
>CP3A1_RAT (P04800) Cytochrome P450 3A1 (EC 1.14.14.1) (CYPIIIA1) (P450-PCN1)| Length = 504 Score = 97.4 bits (241), Expect = 4e-20 Identities = 54/162 (33%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++ ++ L+ +P+ Q++L++E+ + ++P + + +++ + MVL ETLR Sbjct: 307 GYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETLR 366 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY ++R D+ + + +PKG ++IP +HRD + W + +EF+P RF Sbjct: 367 LYPIGNRLERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHW-PEPEEFRPERFSKENK 425 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G+ P+ L F GPR+CIG F+++ K L +LQ FSF Sbjct: 426 GSID-PYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSF 466
>CP4V3_MOUSE (Q9DBW0) Cytochrome P450 4V3 (EC 1.14.-.-)| Length = 525 Score = 97.1 bits (240), Expect = 5e-20 Identities = 62/163 (38%), Positives = 93/163 (57%), Gaps = 4/163 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ T+ + WS+YLL PE Q ++ +E+ + FG +S P L KLK + V+ ET Sbjct: 330 GHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFG-RSHRPVTLEDLKKLKYLDCVIKET 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGI-AIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LR++ R D VG K+ KG AI+IP + HRD + D +EF+P RF Sbjct: 389 LRVFPSVPLFARSLSEDCEVGGYKVTKGTEAIIIPYAL-HRDPRYF-PDPEEFRPERFFP 446 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + P+ + FS GPR+CIGQ F+++E K+ LA +L++F Sbjct: 447 E-NSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQF 488
>CP4F5_RAT (P51870) Cytochrome P450 4F5 (EC 1.14.14.1) (CYPIVF5)| Length = 526 Score = 97.1 bits (240), Expect = 5e-20 Identities = 60/163 (36%), Positives = 94/163 (57%), Gaps = 4/163 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV + + P+ + L +L +TM + E+ Sbjct: 331 GHDTTASALSWILYNLARHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKES 390 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LRL+ PA+ + R+ D+ + + +PKG VI I +H + VW D + F P RF + Sbjct: 391 LRLHPPAIDLLRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVW-PDPEVFDPFRFDS 449 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + P + FS GPR+CIGQ F+M E K +AL L +F Sbjct: 450 E-NRQKRSPLSFIPFSAGPRNCIGQTFAMNEMKVVVALTLLRF 491
>CP4F6_RAT (P51871) Cytochrome P450 4F6 (EC 1.14.14.1) (CYPIVF6)| Length = 537 Score = 96.3 bits (238), Expect = 8e-20 Identities = 68/194 (35%), Positives = 103/194 (53%), Gaps = 4/194 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV + + P+ + L +L +TM + E+ Sbjct: 329 GHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LRL+ P L + R D+ + + +PKG VI I +H + VW D + + P RF + Sbjct: 389 LRLHPPVLLISRCCSQDIVLPDGRVIPKGNICVISIFGVHHNPSVW-PDPEVYNPFRF-D 446 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 + P + FS GPR+CIGQ F+M E K LAL L +F L D Sbjct: 447 PENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFC-VLPDDKEPRRKPELI 505 Query: 175 LKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 506 LRAEGGLWLRVEPL 519
>CP4AA_RAT (P08516) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 96.3 bits (238), Expect = 8e-20 Identities = 63/192 (32%), Positives = 100/192 (52%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +P+ Q+R R+EV G S + L+++ TM + E LR Sbjct: 321 GHDTTASGVSWIFYALATHPKHQQRCREEVQSVLGDGSSITWDHLDQIPYTTMCIKEALR 380 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ +T LPKGI + + I +H + +VW + + F P RF Sbjct: 381 LYPPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVW-PNPEVFDPSRFA--- 436 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + + H L FS G R+CIG+ F+M E K +AL L +F P V P+ LK Sbjct: 437 PDSPRHSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLVLK 496 Query: 169 PKFGLQVFVRPL 134 K G+ ++++ L Sbjct: 497 SKNGIYLYLKKL 508
>THAS_MOUSE (P36423) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| (TS) Length = 533 Score = 96.3 bits (238), Expect = 8e-20 Identities = 67/193 (34%), Positives = 100/193 (51%), Gaps = 8/193 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-SPDPNALNK-LKEMTMVLFETL 530 GHE + L++ YLL+ +P+ QERL KEV G +P+ ++L + L + MV+ ETL Sbjct: 342 GHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETL 401 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 R+Y PA R+ D V ++P G + I + +H D E W + + F P RF Sbjct: 402 RMYPPAFRFTREAAQDCEVLGQRIPAGTVLEIAVGALHHDPEHW-PNPETFDPERF---- 456 Query: 349 TGAAKV---PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI- 182 T A++ P L F GPRSC+G +L K T+ +L KF F SP+ P+ + Sbjct: 457 TAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPE-TQVPLQLE 515 Query: 181 --FTLKPKFGLQV 149 L PK G+ + Sbjct: 516 SKSALGPKNGVYI 528
>CP341_MOUSE (Q9JMA7) Cytochrome P450 3A41 (EC 1.14.14.1)| Length = 504 Score = 95.9 bits (237), Expect = 1e-19 Identities = 52/162 (32%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++++Y L+ +P+ Q++L++E+ + ++P + + +++ + MVL ETLR Sbjct: 307 GYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLNETLR 366 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY ++R D+ + + +PKG ++IP +H D + W + +EF+P RF Sbjct: 367 LYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHW-PEPEEFQPERFSKENK 425 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G+ P+ + F +GPR+CIG F+ + K L ++Q FSF Sbjct: 426 GSID-PYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSF 466
>THAS_RAT (P49430) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 95.9 bits (237), Expect = 1e-19 Identities = 71/194 (36%), Positives = 96/194 (49%), Gaps = 9/194 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNK---LKEMTMVLFET 533 GHE T+ L++ YLL+ +PE QERL KEV F + P P N L + MV+ ET Sbjct: 342 GHEITTNTLSFITYLLATHPECQERLLKEV-DLFMEKHPAPEYCNLQEGLPYLDMVVAET 400 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LR+Y PA R+ D V +P G + I + +H D E W + + F P RF Sbjct: 401 LRMYPPAFRFTREAAQDCEVLGQHIPAGSVLEIAVGALHHDPEHW-PNPETFDPERF--- 456 Query: 352 ITGAAKV---PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 T A++ P L F GPRSC+G +L K TL +L KF F P+ P+ + Sbjct: 457 -TAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPE-TQVPLQL 514 Query: 181 ---FTLKPKFGLQV 149 L PK G+ V Sbjct: 515 ESKSALCPKNGVYV 528
>CP3AE_CAVPO (Q64417) Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14)| Length = 503 Score = 95.9 bits (237), Expect = 1e-19 Identities = 55/166 (33%), Positives = 94/166 (56%), Gaps = 5/166 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G+E TS L++ +Y L+ +P+ Q++L++E+ K ++ P + + +++ + MV+ ETLR Sbjct: 306 GYETTSSTLSFIMYSLATHPDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 LY ++R + D + + PKG ++IP +HRD + W + DEF+P RF K Sbjct: 366 LYPVTNRIERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYW-PEPDEFRPERFSKKNK 424 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 I P+ + F GPR+CIG +++ K L +LQ FSF Sbjct: 425 ENID-----PYIYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP4D2_DROME (Q27589) Cytochrome P450 4d2 (EC 1.14.-.-) (CYPIVD2)| Length = 501 Score = 95.9 bits (237), Expect = 1e-19 Identities = 59/174 (33%), Positives = 96/174 (55%), Gaps = 4/174 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ T+ +++ +Y +S +PE Q+RL++E+ G P L +LK M V+ E+ Sbjct: 312 GHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKES 371 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LRL+ P + R D+ + +P G + I ++ RD E + + DEF+P RF Sbjct: 372 LRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-ESPDEFRPERFDAD 430 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS-FTLSPDYVHA 194 + P+ + FS GPR+CIGQ F+MLE KST++ +L+ F L P+ H+ Sbjct: 431 VPQIH--PYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHS 482
>C4D10_DROMT (O18596) Cytochrome P450 4d10 (EC 1.14.-.-) (CYPIVD10)| Length = 513 Score = 95.5 bits (236), Expect = 1e-19 Identities = 59/181 (32%), Positives = 97/181 (53%), Gaps = 4/181 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ TS +T+ Y +++YPE Q + +E++ G + P + LN L M + + ET Sbjct: 318 GHDTTSSGITFFFYNIALYPECQRKCVEEIVSVLGKDTETPVTYDLLNNLNYMDLCIKET 377 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LR+Y + RK + + + +P G I I + R +++ + + FKP RF + Sbjct: 378 LRMYPSVPLLGRKVLQECEINGKIIPAGTNIGISPLFLGRSEDI-SSEPNTFKPERF-DV 435 Query: 352 ITGAAKV-PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 +T A K+ PH + FS GPR+CIGQ F+MLE K+ A +L+ + + +PV I Sbjct: 436 VTSAEKLNPHAYIPFSAGPRNCIGQKFAMLEIKAIAANVLRHYEIEFVGNAEESPVLIAE 495 Query: 175 L 173 L Sbjct: 496 L 496
>CP4A2_RAT (P20816) Cytochrome P450 4A2 precursor (EC 1.14.15.3) (CYPIVA2)| (Lauric acid omega-hydroxylase) (P450-LA-omega 2) (P450 K-5) (P-450 K-2) Length = 504 Score = 95.5 bits (236), Expect = 1e-19 Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +PE QER R+EV G S + L+++ TM + E LR Sbjct: 316 GHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALR 375 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LYSP + R+ + +T +PKGI + I I +H + W + F P RF Sbjct: 376 LYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYW-PNPKVFDPSRFS--- 431 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + + H L FS G R+CIG+ F+M E K +AL L +F P + P+ LK Sbjct: 432 PDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLK 491 Query: 169 PKFGLQVFVRPL 134 K G+ + ++ L Sbjct: 492 SKNGIHLRLKKL 503
>CP3AB_MOUSE (Q64459) Cytochrome P450 3A11 (EC 1.14.14.1) (CYPIIIA11)| (P-450IIIAM1) (P-450UT) Length = 504 Score = 95.5 bits (236), Expect = 1e-19 Identities = 52/162 (32%), Positives = 96/162 (59%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L+++++ L+ +P+ Q++L+ E+ + ++P + + +++ + MVL ETLR Sbjct: 307 GYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLR 366 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R D+ + + +PKG ++IP +H D + W + +EF+P RF Sbjct: 367 LYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHW-SEPEEFQPERFSKENK 425 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G+ P+ L F GPR+C+G F+++ K L ++Q FSF Sbjct: 426 GSID-PYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSF 466
>CP3AH_CAVPO (Q64409) Cytochrome P450 3A17 (EC 1.14.14.1) (CYPIIIA17)| Length = 503 Score = 95.1 bits (235), Expect = 2e-19 Identities = 55/166 (33%), Positives = 93/166 (56%), Gaps = 5/166 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G+E TS L + +Y L+ +P+ Q++L++E+ K ++ P + + +++ + MV+ ETLR Sbjct: 306 GYETTSSTLCFIMYSLATHPDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 LY ++R + D + + PKG ++IP +HRD + W + DEF+P RF K Sbjct: 366 LYPVTNRIERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYW-PEPDEFRPERFSKKNK 424 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 I P+ + F GPR+CIG +++ K L +LQ FSF Sbjct: 425 ENID-----PYIYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSF 465
>CP3A2_RAT (P05183) Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (P450-PCN2)| (P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Length = 504 Score = 94.7 bits (234), Expect = 2e-19 Identities = 55/162 (33%), Positives = 91/162 (56%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++ +Y L+ +P+ Q++L++E+ ++P + + +++ + MVL ETLR Sbjct: 307 GYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNETLR 366 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY ++R D+ + L +PKG + IP +H D + W +EF P RF Sbjct: 367 LYPIGNRLERVCKKDIELDGLFIPKGSVVTIPTYALHHDPQHW-PKPEEFHPERFSKENK 425 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G+ P+ L F GPR+CIG F+++ K L +LQ FSF Sbjct: 426 GSID-PYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSF 466
>CP3A7_HUMAN (P24462) Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (P450-HFLA)| Length = 503 Score = 94.7 bits (234), Expect = 2e-19 Identities = 53/166 (31%), Positives = 98/166 (59%), Gaps = 5/166 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS +L++ +Y L+ +P+ Q++++KE+ ++P + + +L+ + MV+ ETLR Sbjct: 306 GYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 L+ A+ ++R D+ + + +PKG+ ++IP ++H D + W + ++F P RF K Sbjct: 366 LFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYW-REPEKFLPERFSKKNK 424 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + I P+ F GPR+CIG F+++ K L +LQ FSF Sbjct: 425 DNID-----PYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSF 465
>C13B1_CAEEL (O17624) Putative cytochrome P450 cyp-13B1 (EC 1.14.-.-)| Length = 527 Score = 94.7 bits (234), Expect = 2e-19 Identities = 52/160 (32%), Positives = 92/160 (57%), Gaps = 1/160 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G + T+ L ++ YLL+ +PE + ++EV G ++ + + KLK + V+ E+LRL Sbjct: 321 GFDTTANSLAYASYLLAKHPEKMKLAQEEVDTVVGSENVSYDDMTKLKYLDAVVRESLRL 380 Query: 523 YSPALFM-QRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 Y A F R+ V T+G + + KG+ I + +HR KE+WG++AD+F P R+ + Sbjct: 381 YPVAWFACSRECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWGENADDFVPERW---LE 437 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 +++ + F GPR C+G + EAK+ LA +L+++ Sbjct: 438 PSSRHTMSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRY 477
>CP3AF_CAVPO (Q64406) Cytochrome P450 3A15 (EC 1.14.14.1) (CYPIIIA15)| Length = 503 Score = 94.4 bits (233), Expect = 3e-19 Identities = 55/166 (33%), Positives = 94/166 (56%), Gaps = 5/166 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G+E +S L+ +Y L+ +P+ Q++L +E+ K ++ P + + +++ + MV+ ETLR Sbjct: 306 GYETSSSTLSCIMYSLATHPDVQKKLHQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 LY A ++R + D + + PKG ++IP +HRD + W + DEF+P RF K Sbjct: 366 LYPVANRIERMSKKDFEINGMSFPKGTLVMIPSFALHRDSKYW-PEPDEFRPERFSKKNK 424 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 I P+ + F GPR+CIG+ +++ K L +LQ FSF Sbjct: 425 ENID-----PYIYMPFGNGPRNCIGRRMALMNLKLALIRLLQNFSF 465
>CP3A9_RAT (P51538) Cytochrome P450 3A9 (EC 1.14.14.1) (CYPIIIA9) (P450-OLF3)| (Olfactive) (3AH15) Length = 503 Score = 94.4 bits (233), Expect = 3e-19 Identities = 55/162 (33%), Positives = 93/162 (57%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++ +YLL+I+P+ Q++L+ E+ ++ + L +++ + MV+ ETLR Sbjct: 306 GYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R D+ + + +PKG ++IP +H+D W + +EF+P RF Sbjct: 366 LYPIAGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYW-PEPEEFRPERFSKKNQ 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 P+ L F GPR+CIG F+++ K L +LQ FSF Sbjct: 425 DNIN-PYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSF 465
>CP4A6_RABIT (P14580) Cytochrome P450 4A6 precursor (EC 1.14.15.3) (CYPIVA6)| (Lauric acid omega-hydroxylase) (P450-KA-1) Length = 510 Score = 94.0 bits (232), Expect = 4e-19 Identities = 63/192 (32%), Positives = 97/192 (50%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +PE Q R R+E+ G S L+++ TM + E LR Sbjct: 322 GHDTTASGISWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEALR 381 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ + +T LPKG+ + + I +H + +VW + + F P F Sbjct: 382 LYPPVPGVGRQLSSPVTFPDGRSLPKGVIVTLSIYALHHNPKVW-PNPEVFDPFPFA--- 437 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 G+A+ H L FS GPR+CIG+ F+M E K +AL L +F P V LK Sbjct: 438 PGSARHSHAFLPFSGGPRNCIGKQFAMNELKVAVALTLVRFELLPDPKRVPDQKPRLVLK 497 Query: 169 PKFGLQVFVRPL 134 G+ + +R L Sbjct: 498 SSNGIHLRLRKL 509
>CP4AA_MOUSE (O88833) Cytochrome P450 4A10 (EC 1.14.15.3) (CYPIVA10) (Lauric| acid omega-hydroxylase) (P450-LA-omega 1) (P452) Length = 509 Score = 94.0 bits (232), Expect = 4e-19 Identities = 62/192 (32%), Positives = 99/192 (51%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +P+ Q+R R+EV G S + L+++ TM + E LR Sbjct: 321 GHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALR 380 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ +T LPKG+ + + I +H + +VW + + F P RF Sbjct: 381 LYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVW-PNPEVFDPSRFA--- 436 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + + H L FS G R+CIG+ F+M E K +AL L +F P V P+ LK Sbjct: 437 PDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLK 496 Query: 169 PKFGLQVFVRPL 134 K G+ + ++ L Sbjct: 497 SKNGIYLHLKKL 508
>CP3AV_MESAU (O70537) Cytochrome P450 3A31 (EC 1.14.14.1) (CYPIIIA31) (P450| SH3A-1) Length = 501 Score = 93.6 bits (231), Expect = 5e-19 Identities = 53/163 (32%), Positives = 96/163 (58%), Gaps = 3/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMT---MVLFET 533 G++ TS L++++YLL+ +P+ Q++L++E+ + + + + +K+ EM MVL ET Sbjct: 304 GYDTTSSTLSFALYLLATHPDVQKKLQEEI--DIALPNKARPSYDKVMEMEYLDMVLNET 361 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LRLY ++R D+ + + +PKG +++P+ +H D + W + ++F+P RF Sbjct: 362 LRLYPIGSRLERVCKQDVEMDGVFVPKGSIVMVPVFALHYDPQYW-PEPEKFRPERFSKE 420 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 224 G+ P+ L F GPR+CIG F+++ K L +LQ FS Sbjct: 421 NKGSID-PYIFLPFGNGPRNCIGMRFALMNMKLALTKVLQNFS 462
>CP4AE_MOUSE (O35728) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase 3) (P450-LA-omega 3) Length = 507 Score = 93.6 bits (231), Expect = 5e-19 Identities = 62/192 (32%), Positives = 96/192 (50%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +PE Q+R R+EV G S + L ++ TM + E LR Sbjct: 319 GHDTTASGISWIFYALATHPEHQQRCREEVQSILGDGTSVTWDHLGQMPYTTMCIKEALR 378 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + + R+ + +T +PKGI I I +H + W + F P RF Sbjct: 379 LYPPVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPRFW-PNPKVFDPSRFA--- 434 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 ++ H L FS G R+CIG+ F+M E K +AL L +F P + P+ LK Sbjct: 435 PDSSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPIARLVLK 494 Query: 169 PKFGLQVFVRPL 134 K G+ + ++ L Sbjct: 495 SKNGIHLCLKKL 506
>CP4F4_RAT (P51869) Cytochrome P450 4F4 (EC 1.14.14.1) (CYPIVF4)| Length = 522 Score = 93.6 bits (231), Expect = 5e-19 Identities = 67/198 (33%), Positives = 102/198 (51%), Gaps = 8/198 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV L++ + + L +L +TM + E+ Sbjct: 329 GHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGD----DADEFKPL 368 LRL+ P + R+ D+ + + +PKG+ +I I H + VW D D F P Sbjct: 389 LRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPE 448 Query: 367 RFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPV 188 K+ + P + FS GPR+CIGQ F+M E K LAL L +F L D Sbjct: 449 NIKD------RSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFR-VLPDDKEPRRK 501 Query: 187 DIFTLKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 502 PELILRAEGGLWLRVEPL 519
>CP4FE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukotriene-B4| omega-hydroxylase) (Leukotriene-B4 20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14) Length = 524 Score = 93.6 bits (231), Expect = 5e-19 Identities = 68/195 (34%), Positives = 104/195 (53%), Gaps = 5/195 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV + + P+ + L +L +TM + E+ Sbjct: 329 GHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPEEIEWDDLAQLPFLTMCIKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK- 359 LRL+ P + R D+ + + +PKGI +I I +H + VW D + + P RF Sbjct: 389 LRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYDPFRFDP 447 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIF 179 I ++ P + FS GPR+CIGQ F+M E K LAL L +F L D Sbjct: 448 ENIKDSS--PLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRL-LPDDKEPRRQPEL 504 Query: 178 TLKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 505 ILRAEGGLWLRVEPL 519
>CP4F8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)| Length = 520 Score = 93.2 bits (230), Expect = 7e-19 Identities = 69/195 (35%), Positives = 103/195 (52%), Gaps = 5/195 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV LK+ + + + L +L +TM L E+ Sbjct: 329 GHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKES 388 Query: 532 LRLYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LRL+ P R D+ + S +PKG I I +H + VW D + + P RF + Sbjct: 389 LRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVW-PDPEVYDPFRF-D 446 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-APVDIF 179 + P + FS GPR+CIGQ F+M E K LAL L + F + PD+ Sbjct: 447 PENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLR--FRILPDHREPRRTPEI 504 Query: 178 TLKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 505 VLRAEDGLWLRVEPL 519
>CP4A4_RABIT (P10611) Cytochrome P450 4A4 precursor (EC 1.14.14.1) (CYPIVA4)| (Prostaglandin omega-hydroxylase) (P450-P-2) Length = 510 Score = 93.2 bits (230), Expect = 7e-19 Identities = 63/192 (32%), Positives = 97/192 (50%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +PE Q R R+E+ G S L+++ TM + E LR Sbjct: 322 GHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEALR 381 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ +T LPKG+ + + I +H + +VW + + F P RF Sbjct: 382 LYPPVPSVTRQLSKPVTFPDGRSLPKGVILFLSIYGLHYNPKVW-QNPEVFDPFRFA--- 437 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 +A H L FS G R+CIG+ F+M E K +AL L +F P + P+ LK Sbjct: 438 PDSAYHSHAFLPFSGGARNCIGKQFAMRELKVAVALTLVRFELLPDPTRIPIPIARVVLK 497 Query: 169 PKFGLQVFVRPL 134 K G+ + +R L Sbjct: 498 SKNGIHLRLRKL 509
>CP4AC_RAT (P24464) Cytochrome P450 4A12 (EC 1.14.14.1) (CYPIVA12) (CYPIVA8)| (P450-KP1) (P450-PP1) Length = 508 Score = 92.8 bits (229), Expect = 9e-19 Identities = 61/192 (31%), Positives = 96/192 (50%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ PE Q+ RKE+ G S + L+K+ TM + E LR Sbjct: 320 GHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKEALR 379 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 +Y P + R +T LPKGI +++ +H + VW + + F P RF Sbjct: 380 IYPPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRFA--- 435 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 +++ H L FS G R+CIG+ F+M E K +AL L +F P + P+ LK Sbjct: 436 PESSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLK 495 Query: 169 PKFGLQVFVRPL 134 K G+ + ++ L Sbjct: 496 SKNGIYLRLKKL 507
>THAS_PIG (P47787) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 534 Score = 92.4 bits (228), Expect = 1e-18 Identities = 63/195 (32%), Positives = 96/195 (49%), Gaps = 6/195 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNK---LKEMTMVLFET 533 G+E + L++ YLL+ P+ QE+L +EV +F + P P + L + MVL ET Sbjct: 343 GYEIITNTLSFVTYLLATNPDCQEKLLREV-DDFSKKHPSPEHCSLQQGLPYLDMVLSET 401 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LR+Y PA R+ D V ++P G + + + +H D + W + F P RF Sbjct: 402 LRMYPPAFRFTREAARDCEVLGQRIPAGTVLEVAVGALHHDPKHW-PHPETFDPERF-TA 459 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI--- 182 + P L F GPRSC+G +LE K TL +L+KF F P+ P+ + Sbjct: 460 EAQRLQQPFTYLPFGAGPRSCLGVQLGLLEIKLTLLHILRKFRFEACPE-TQVPLQLESK 518 Query: 181 FTLKPKFGLQVFVRP 137 L PK G+ + + P Sbjct: 519 SALSPKNGVYIRIVP 533
>CP4A5_RABIT (P14579) Cytochrome P450 4A5 precursor (EC 1.14.15.3) (CYPIVA5)| (Lauric acid omega-hydroxylase) Length = 511 Score = 92.4 bits (228), Expect = 1e-18 Identities = 62/192 (32%), Positives = 95/192 (49%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +PE Q R R+E+ G S L+++ TM + E +R Sbjct: 323 GHDTTASGVSWIFYALATHPEHQHRCREEIQGLLGDGASITWEHLDQMPYTTMCIKEAMR 382 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R + +T LPKG + + I +H + VW + + F P RF Sbjct: 383 LYPPVPAISRDLSSPVTFPDGRSLPKGFTVTLSIYGLHHNPNVW-PNPEVFDPGRFT--- 438 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 G+A+ H L FS G R+CIG+ F+M E K +AL L +F P + P LK Sbjct: 439 PGSARHSHAFLPFSGGARNCIGKQFAMNELKVAVALTLVRFELLPDPTRIPKPTARLVLK 498 Query: 169 PKFGLQVFVRPL 134 G+ + +R L Sbjct: 499 SNNGIHLRLRKL 510
>CP4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)| Length = 501 Score = 92.4 bits (228), Expect = 1e-18 Identities = 54/167 (32%), Positives = 86/167 (51%), Gaps = 6/167 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETL 530 GH+ S +TW ++ L +PE QE KEV F P LN + + V+ E+L Sbjct: 310 GHDTVSAAMTWLLFELGHHPEIQEEAYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESL 369 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRF 362 RL+ ++ R+ D +G +P G I +P +HR+ E++ + + D F P R Sbjct: 370 RLHPSVIYFVREAHQDFELGGYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRV 429 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 N + P+ + FS GPR+CIGQ F++LE K L+ +L+ + F Sbjct: 430 VN------RHPYAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRF 470
>CP4F2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 92.4 bits (228), Expect = 1e-18 Identities = 67/195 (34%), Positives = 104/195 (53%), Gaps = 5/195 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV LK+ + + + L L +TM + E+ Sbjct: 329 GHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LRL+ P + R D+ + + +PKGI +I + H + VW D + + P RF + Sbjct: 389 LRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF-D 446 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-APVDIF 179 + P + FS GPR+CIGQ F+M E K LAL L + F + PD+ Sbjct: 447 PENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLR--FRVLPDHTEPRRKPEL 504 Query: 178 TLKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 505 VLRAEGGLWLRVEPL 519
>CP4F1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (P450-A3)| Length = 524 Score = 92.0 bits (227), Expect = 2e-18 Identities = 68/195 (34%), Positives = 103/195 (52%), Gaps = 5/195 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ PE+QER R+EV + + P+ + L +L +TM + E+ Sbjct: 329 GHDTTASGLSWILYNLANDPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK- 359 LRL+ P + R D+ + + +PKGI +I I +H + VW D + + P RF Sbjct: 389 LRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYNPFRFDP 447 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIF 179 I ++ P + FS GPR+CIGQ F+M E K LAL L +F L D Sbjct: 448 ENIKDSS--PLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRL-LPDDKEPRRQPEL 504 Query: 178 TLKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 505 ILRAEGGLWLRVEPL 519
>CP3A6_RABIT (P11707) Cytochrome P450 3A6 (EC 1.14.14.1) (CYPIIIA6) (P450-3C)| Length = 501 Score = 92.0 bits (227), Expect = 2e-18 Identities = 57/170 (33%), Positives = 97/170 (57%), Gaps = 7/170 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 G+E TS L++ ++LL+ +P+ Q++L++E+ L + + D L K++ + MV+ ET Sbjct: 304 GYETTSSTLSFIMHLLATHPDVQQKLQEEIDTLLPNKELATYD--TLVKMEYLDMVVNET 361 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--- 362 LRLY A ++R D+ + +PKG +++P +HRD + W + DEF+P RF Sbjct: 362 LRLYPIAGRLERVCKKDVDINGTFIPKGTIVMMPTYALHRDPQHW-TEPDEFRPERFSKK 420 Query: 361 -KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 K+ I P+ F GPR+C+G F+++ K L ++Q FSF L Sbjct: 421 NKDNIN-----PYIYHPFGAGPRNCLGMRFALMNIKLALVRLMQNFSFKL 465
>CP4AE_RAT (P20817) Cytochrome P450 4A14 precursor (EC 1.14.15.3) (CYPIVA14)| (Lauric acid omega-hydroxylase) (P450-LA-omega 3) Length = 507 Score = 92.0 bits (227), Expect = 2e-18 Identities = 63/192 (32%), Positives = 96/192 (50%), Gaps = 2/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 GH+ T+ ++W Y L+ +PE QER R+EV G S + L+++ TM + E LR Sbjct: 319 GHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQIPYTTMCIKEALR 378 Query: 526 LYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY P + R+ + +T +PKGI I I +H + W + F P RF Sbjct: 379 LYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYW-PNPKVFDPSRFS--- 434 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 + + H L FS G R+CIG+ F+M E K +AL L +F P + P+ LK Sbjct: 435 PDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLVLK 494 Query: 169 PKFGLQVFVRPL 134 K G+ + ++ L Sbjct: 495 SKNGIHLRLKKL 506
>CP4D8_DROME (Q9VS79) Cytochrome P450 4d8 (EC 1.14.-.-) (CYPIVD8)| Length = 463 Score = 91.3 bits (225), Expect = 3e-18 Identities = 65/196 (33%), Positives = 104/196 (53%), Gaps = 8/196 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA---LNKLKEMTMVLFET 533 GH+ T+ L++ ++ LS +PE Q ++ +E+++ G P + L +LK M V+ E+ Sbjct: 268 GHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKES 327 Query: 532 LRLYSPALFMQRKTVADMTV-----GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 LR+Y P + RK D G +P G I+I I +HR E + + DEF P Sbjct: 328 LRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETF-PNPDEFIPE 386 Query: 367 RFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPV 188 R +NG A P ++ FS GPR+CIGQ F+ LE K LA +++++ V V Sbjct: 387 RHENGSRVA---PFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIV 443 Query: 187 DIFTLKPKFGLQVFVR 140 +I L+ + G Q+ +R Sbjct: 444 NI-VLRSETGFQLGMR 458
>CP56_YEAST (P21595) Cytochrome P450-DIT2 (EC 1.14.14.-) (Cytochrome P450 56)| Length = 489 Score = 91.3 bits (225), Expect = 3e-18 Identities = 66/195 (33%), Positives = 99/195 (50%), Gaps = 14/195 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYP-EWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLR 527 GHEN LL S+YLL+ Y EWQE+LRKEV DP L L + LFE +R Sbjct: 294 GHENPQLLFNSSLYLLAKYSNEWQEKLRKEV-----NGITDPKGLADLPLLNAFLFEVVR 348 Query: 526 LYSP-ALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 +Y P + + R T +G+ + +PKG+ + D + WG AD+FKP R+ + Sbjct: 349 MYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSD 408 Query: 352 IT------GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-- 197 I AK + F G R+C+G+ ++ E + +LA ML++F ++L P++ Sbjct: 409 IETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKL 468 Query: 196 ---APVDIFTLKPKF 161 P+ LK KF Sbjct: 469 TPAGPLCPLNLKLKF 483
>CP3A4_HUMAN (P08684) Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine| 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) (Taurochenodeoxycholate 6-alpha-hydroxylase) (EC 1.14.13.97) (NF-25) (P450-PCN1) Length = 502 Score = 90.9 bits (224), Expect = 3e-18 Identities = 53/166 (31%), Positives = 97/166 (58%), Gaps = 5/166 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS +L++ +Y L+ +P+ Q++L++E+ ++P + + +++ + MV+ ETLR Sbjct: 305 GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLR 364 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 L+ A+ ++R D+ + + +PKG ++IP +HRD + W + ++F P RF K Sbjct: 365 LFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPERFSKKNK 423 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + I P+ F GPR+CIG F+++ K L +LQ FSF Sbjct: 424 DNID-----PYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSF 464
>C97B3_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)| Length = 580 Score = 90.9 bits (224), Expect = 3e-18 Identities = 61/192 (31%), Positives = 95/192 (49%), Gaps = 29/192 (15%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE T+ +LTW+V+LLS PE + + E+ G P ++ KL+ + +++ E LRL Sbjct: 360 GHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLGQGPPTYESMKKLEYIRLIVVEVLRL 419 Query: 523 YSPALFMQRKTVADMTV--------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 + + R+T+ T+ K+PKG I I + +HR W D+ +F+P Sbjct: 420 FPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPYFW-DNPHDFEPE 478 Query: 367 RF-----KNGITG----------AAKVPHGLLA------FSMGPRSCIGQNFSMLEAKST 251 RF NGI G A P+ ++A F GPR CIG F+++E+ Sbjct: 479 RFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFALMESTVA 538 Query: 250 LALMLQKFSFTL 215 LA++ QKF L Sbjct: 539 LAMLFQKFDVEL 550
>CP3A3_HUMAN (P05184) Cytochrome P450 3A3 (EC 1.14.14.1) (CYPIIIA3) (HLp)| Length = 503 Score = 90.9 bits (224), Expect = 3e-18 Identities = 53/166 (31%), Positives = 97/166 (58%), Gaps = 5/166 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS +L++ +Y L+ +P+ Q++L++E+ ++P + + +++ + MV+ ETLR Sbjct: 306 GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 L+ A+ ++R D+ + + +PKG ++IP +HRD + W + ++F P RF K Sbjct: 366 LFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYW-TEPEKFLPERFSKKNK 424 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + I P+ F GPR+CIG F+++ K L +LQ FSF Sbjct: 425 DNID-----PYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP3A8_MACFA (P33268) Cytochrome P450 3A8 (EC 1.14.14.1) (CYPIIIA8) (P450-MKNF2)| (P-450-MK2) Length = 503 Score = 90.5 bits (223), Expect = 4e-18 Identities = 48/162 (29%), Positives = 94/162 (58%), Gaps = 1/162 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS +L++ +Y L+ +P+ Q++L++E+ ++P + + +++ + MV+ ETLR Sbjct: 306 GYETTSSVLSFIIYELATHPDVQQKLQEEIDTVLPNKAPPTYDTVLQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 ++ A+ ++R D+ + + +PKG+ ++IP +H D + W + ++F P RF Sbjct: 366 IFPIAMRLERVCKKDVEINGIFIPKGVVVMIPSYALHHDPKYW-PEPEKFLPERFSKKNN 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 P+ F GPR+CIG F+++ K + +LQ FSF Sbjct: 425 DNID-PYIYTPFGSGPRNCIGMRFALMNMKLAIIRVLQNFSF 465
>C340_ORYLA (Q98T91) Cytochrome P450 3A40 (EC 1.14.14.1)| Length = 502 Score = 90.5 bits (223), Expect = 4e-18 Identities = 59/193 (30%), Positives = 104/193 (53%), Gaps = 4/193 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA-LNKLKEMTMVLFETLR 527 G+E TS LT+ Y L+ PE ++L+KE+ F ++P L +++ + V+ E+LR Sbjct: 307 GYETTSSSLTFLAYNLATNPEVMKKLQKEIDATFPNKAPVQYVPLMEMEYLDCVVNESLR 366 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R A + V L +PK + +++P +HRD E+W + ++FKP RF Sbjct: 367 LYPIAARLERVAKATVEVNGLVIPKDMVVMVPTWPLHRDPELW-PEPEKFKPERFSKENK 425 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT--- 176 P+ + F GPR+CIG F+++ K + +LQ + F++ + P ++ Sbjct: 426 DTFD-PYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSVCKE-TEVPFEMDVQGF 483 Query: 175 LKPKFGLQVFVRP 137 L PK +Q+ + P Sbjct: 484 LAPKRPIQLKLTP 496
>CP3AA_MESAU (Q64148) Cytochrome P450 3A10 (EC 1.14.13.94) (CYPIIIA10)| (Lithocholate 6-beta-hydroxylase) (6 beta-hydroxylase) Length = 503 Score = 89.7 bits (221), Expect = 8e-18 Identities = 52/161 (32%), Positives = 91/161 (56%), Gaps = 1/161 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E+TS + +Y L+ +P+ Q++L E+ ++P + L ++ + MV+ E LR Sbjct: 306 GYESTSTSICLVLYELATHPDVQKKLHDEIDSALPNKAPVTYDVLMGMEYLDMVINEGLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R + + + L +PKGI +++P +HRD E W + +EF+P RF Sbjct: 366 LYPIANRLERISKKAVEINGLFIPKGITVMVPTYPLHRDPEYW-PEPEEFRPERFSKENK 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 224 G+ P+ + F GPR+CIG F++L K + +LQ F+ Sbjct: 425 GSID-PYVYMPFGNGPRNCIGMRFALLSMKLAVVSVLQNFT 464
>CP4F3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)| (Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB-omega) Length = 520 Score = 89.4 bits (220), Expect = 1e-17 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 5/195 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QER R+EV LK+ + + + L +L +TM + E+ Sbjct: 329 GHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LRL+ P + R D+ + + +PKGI +I + H + VW D + + P RF + Sbjct: 389 LRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF-D 446 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH-APVDIF 179 + P + FS GPR+CIGQ F+M E K L L L + F + PD+ Sbjct: 447 PKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLR--FRVLPDHTEPRRKPEL 504 Query: 178 TLKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 505 VLRAEGGLWLRVEPL 519
>THAS_HUMAN (P24557) Thromboxane-A synthase (EC 5.3.99.5) (TXA synthase) (TXS)| Length = 533 Score = 89.4 bits (220), Expect = 1e-17 Identities = 64/193 (33%), Positives = 94/193 (48%), Gaps = 8/193 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETL 530 G+E + L+++ YLL+ P+ QE+L +EV KE M + L + MV+ ETL Sbjct: 342 GYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETL 401 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 R+Y PA R+ D V ++P G + + + +H D E W + F P RF Sbjct: 402 RMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHW-PSPETFNPERF---- 456 Query: 349 TGAAKVPH---GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI- 182 T A+ H L F GPRSC+G +LE K TL +L KF F P+ P+ + Sbjct: 457 TAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPE-TQVPLQLE 515 Query: 181 --FTLKPKFGLQV 149 L PK G+ + Sbjct: 516 SKSALGPKNGVYI 528
>CP3AL_CALJA (O18993) Cytochrome P450 3A21 (EC 1.14.14.1) (CYPIIIA21) (P450| CM3A-10) Length = 503 Score = 89.4 bits (220), Expect = 1e-17 Identities = 52/163 (31%), Positives = 95/163 (58%), Gaps = 2/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G+E TS L++ +Y L+ +P+ Q++L++E+ ++P + + +++ + MV+ ETLR Sbjct: 306 GYETTSSTLSFIMYELATHPDVQQKLQEEIDAVLPNKAPATYDTVLQMEYLDMVVNETLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGI 350 L+ A+ ++R D+ + + +PKG+ ++IP +H D + W + ++F P RF KN Sbjct: 366 LFPLAMRLERVCKKDVEINGVFIPKGVVVMIPSYALHYDPKYW-TEPEKFLPERFSKNNK 424 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 P+ F GPR+CIG F+++ K L +LQ FSF Sbjct: 425 DNID--PYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSF 465
>CP3AI_RAT (Q64581) Cytochrome P450 3A18 (EC 1.14.14.1) (CYPIIIA18)| (P450(6)beta-2) Length = 497 Score = 89.4 bits (220), Expect = 1e-17 Identities = 52/161 (32%), Positives = 93/161 (57%), Gaps = 1/161 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G++ TS +++ +Y L+ P Q++L+ E+ + ++P +AL +++ + MV+ E+LR Sbjct: 306 GYDATSTSISFIMYELATRPNVQKKLQNEIDRALPNKAPVTYDALMEMEYLDMVVNESLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A + R + D+ + + +PKG + IPI +HR+ E W + +EF P RF Sbjct: 366 LYPIATRLDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYW-LEPEEFNPERFSKENK 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 224 G+ P+ L F GPR+CIG F+++ K + +LQ F+ Sbjct: 425 GSID-PYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFN 464
>CP52W_CANAP (Q12573) Cytochrome P450 52E2 (EC 1.14.14.-) (CYPLIIE2)| Length = 519 Score = 89.4 bits (220), Expect = 1e-17 Identities = 58/184 (31%), Positives = 93/184 (50%), Gaps = 14/184 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKE---MTMVLFET 533 G + T+ LL+++ Y L YPE + LR+ V+ +FG +P +LK+ + V+ E Sbjct: 313 GRDTTAALLSFTTYYLGAYPEVYDELREAVIADFGSADAEPPTFEQLKQCKVLQNVIREV 372 Query: 532 LRLYSPALFMQRKTVADMTVGS---------LKLPKGIAIVIPIPIMHRDKEVWGDDADE 380 LRL+ R+ +AD T + + +PKG + +M R+ +WG D+ Sbjct: 373 LRLHPNVPLNFREAIADTTFPTGGGPNGDQPIFVPKGQKVFYATYVMQRNAGIWGPDSTS 432 Query: 379 FKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS--FTLSPD 206 F+P R+ N A + F+ GPR C+GQ F++ EA TL + Q+FS L PD Sbjct: 433 FRPDRW-NEPREALASGWDYIPFNGGPRICLGQQFALTEASYTLVRICQEFSRIEVLHPD 491 Query: 205 YVHA 194 + A Sbjct: 492 VITA 495
>CP4FB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)| Length = 524 Score = 89.0 bits (219), Expect = 1e-17 Identities = 65/194 (33%), Positives = 102/194 (52%), Gaps = 4/194 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP---DPNALNKLKEMTMVLFET 533 GH+ T+ L+W +Y L+ +PE+QE+ R+EV + + P + + L +L +TM + E+ Sbjct: 329 GHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKES 388 Query: 532 LRLYSPALFMQRKTVADMTVGSLK-LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 LRL+ P + R D + + +PKGI +I I +H + VW D + + P RF N Sbjct: 389 LRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRF-N 446 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 + P + FS GPR+CIGQ F+M E K LAL L F + ++ Sbjct: 447 QENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELI- 505 Query: 175 LKPKFGLQVFVRPL 134 L+ + GL + V PL Sbjct: 506 LRAEGGLWLRVEPL 519
>CP4V2_PONPY (Q5RCN6) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 89.0 bits (219), Expect = 1e-17 Identities = 54/161 (33%), Positives = 84/161 (52%), Gaps = 2/161 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETL 530 GH+ T+ + WS+YLL PE Q+++ E+ FG L KL+ + V+ ETL Sbjct: 330 GHDTTAAAINWSLYLLGCNPEVQQKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETL 389 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 RL+ R D V ++ KG VI +HRD + + +EF+P RF Sbjct: 390 RLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPE- 447 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + P+ + FS GPR+CIGQ F+++E K+ L+ +L+ F Sbjct: 448 NAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHF 488
>CP134_DROME (Q9VG40) Probable cytochrome P450 313a4 (EC 1.14.-.-)| (CYPCCCXIIIA4) Length = 478 Score = 88.6 bits (218), Expect = 2e-17 Identities = 53/167 (31%), Positives = 95/167 (56%), Gaps = 5/167 (2%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMT---MVLFETLR 527 E T+ + +++ LL+++PE+QER +E+ F + ++M ++L E++R Sbjct: 286 ETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMR 345 Query: 526 LYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNG 353 + P + R+T D+ + + + +PKG+ I I I MHR K++WG DA+ F P F + Sbjct: 346 VIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHN 405 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 212 I K P+ + F+ G R+CIG ++++ AK TLA +L+ + F S Sbjct: 406 IQD--KHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTS 450
>CP3AP_MOUSE (O09158) Cytochrome P450 3A25 (EC 1.14.14.1) (CYPIIIA25)| Length = 503 Score = 88.6 bits (218), Expect = 2e-17 Identities = 51/161 (31%), Positives = 94/161 (58%), Gaps = 1/161 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLR 527 G++ TS ++ +Y L+ +P+ Q++L+ E+ + ++P +AL ++ + MV+ E+LR Sbjct: 306 GYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLR 365 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A+ ++R + D+ + + +PKG ++IPI +HR+ E W + EF P RF Sbjct: 366 LYPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPERFSKENK 424 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 224 G P+ + F GPR+CIG F+++ K + +LQ F+ Sbjct: 425 GNID-PYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFT 464
>CP4V2_HUMAN (Q6ZWL3) Cytochrome P450 4V2 (EC 1.14.-.-)| Length = 525 Score = 88.2 bits (217), Expect = 2e-17 Identities = 54/161 (33%), Positives = 84/161 (52%), Gaps = 2/161 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETL 530 GH+ T+ + WS+YLL PE Q+++ E+ FG L KL+ + V+ ETL Sbjct: 330 GHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETL 389 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 RL+ R D V ++ KG VI +HRD + + +EF+P RF Sbjct: 390 RLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERFFPE- 447 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + P+ + FS GPR+CIGQ F+++E K+ L+ +L+ F Sbjct: 448 NAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHF 488
>CP4D1_DROSI (O16805) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 88.2 bits (217), Expect = 2e-17 Identities = 57/180 (31%), Positives = 90/180 (50%), Gaps = 3/180 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ TS L + Y ++ +PE Q++ +E+ G P LN+L + + + ET Sbjct: 317 GHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKET 376 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LR+Y + RK + D + +P G I I + R +E++ + + FKP RF Sbjct: 377 LRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVV 435 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 T P+ + FS GPR+CIGQ F+MLE K+ +A +L+ + D PV I L Sbjct: 436 TTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAEL 495
>CP4D1_DROME (P33269) Cytochrome P450 4d1 (EC 1.14.-.-) (CYPIVD1)| Length = 512 Score = 88.2 bits (217), Expect = 2e-17 Identities = 57/180 (31%), Positives = 90/180 (50%), Gaps = 3/180 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ TS L + Y ++ +PE Q++ +E+ G P LN+L + + + ET Sbjct: 317 GHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKET 376 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LR+Y + RK + D + +P G I I + R +E++ + + FKP RF Sbjct: 377 LRMYPSVPLLGRKVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEP-NSFKPERFDVV 435 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 T P+ + FS GPR+CIGQ F+MLE K+ +A +L+ + D PV I L Sbjct: 436 TTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAEL 495
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reductase 1| [Includes: Cytochrome P450 102 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1061 Score = 88.2 bits (217), Expect = 2e-17 Identities = 58/181 (32%), Positives = 93/181 (51%), Gaps = 2/181 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE TS LL+++ Y L +P+ ++ +EV + +P + +L + M+L E+LRL Sbjct: 268 GHETTSGLLSFATYFLLKHPDKLKKAYEEVDRVLTDAAPTYKQVLELTYIRMILNESLRL 327 Query: 523 YSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 + A D +G + I + IP +HRD++ WG DA+EF+P RF++ Sbjct: 328 WPTAPAFSLYPKEDTVIGGKFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEH--- 384 Query: 346 GAAKVP-HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLK 170 +VP H F G R+CIG F++ EA L ++L+ F+ +Y TLK Sbjct: 385 -QDQVPHHAYKPFGNGQRACIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLK 443 Query: 169 P 167 P Sbjct: 444 P 444
>CP131_DROME (Q9VFJ0) Probable cytochrome P450 313a1 (EC 1.14.-.-)| (CYPCCCXIIIA1) Length = 492 Score = 87.4 bits (215), Expect = 4e-17 Identities = 64/198 (32%), Positives = 104/198 (52%), Gaps = 14/198 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV------LKEFGMQSPDPNALNKLKEMTMVL 542 G++ ++L + +++LL+ +PE QE + +E+ FG+ PD + KL + V+ Sbjct: 298 GYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPD---MQKLDYLERVI 354 Query: 541 FETLRLYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLR 365 ETLRL R+T D+ + + + +PKG+ I I + HR+ EVWG DAD F P Sbjct: 355 KETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDN 414 Query: 364 FKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF---TLSPDYVHA 194 F K P+ + F+ G R+CIG ++M+ +K L +L+ + TL D V+ Sbjct: 415 FL-AENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKDLVY- 472 Query: 193 PVDIFTLK----PKFGLQ 152 VD T+K P+ LQ Sbjct: 473 -VDNMTMKLAEYPRLKLQ 489
>C356_FUNHE (Q8AXY5) Cytochrome P450 3A56 (EC 1.14.14.1) (CYPIIIA56)| Length = 496 Score = 85.9 bits (211), Expect = 1e-16 Identities = 52/168 (30%), Positives = 96/168 (57%), Gaps = 5/168 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 G+E +S LT+ Y L+ PE ++L++E+ F ++P L +++ + V+ E+LR Sbjct: 305 GYETSSSSLTFLAYNLATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLR 364 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 L+ A ++R A + + + +PK + ++IP +HRD E+W + + FKP RF K Sbjct: 365 LFPIAARLERVAKAAVEINGIVIPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKKNK 423 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 + I P+ + F GPR+CIG F+++ K + +LQ++SF++ Sbjct: 424 DNID-----PYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>C330_FUNHE (Q9PVE8) Cytochrome P450 3A30 (EC 1.14.14.1) (CYPIIIA30)| Length = 496 Score = 85.5 bits (210), Expect = 1e-16 Identities = 52/168 (30%), Positives = 96/168 (57%), Gaps = 5/168 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 G+E +S LT+ Y L+ PE ++L++E+ F ++P L +++ + V+ E+LR Sbjct: 305 GYETSSSSLTFLAYNLATNPEVMKKLQEEIDATFPNKAPVHYQPLMEMEYLDCVINESLR 364 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF----K 359 L+ A ++R A + + + +PK + ++IP +HRD E+W + + FKP RF K Sbjct: 365 LFPIAARLERVAKAAVEINGVVIPKDMVVMIPTWPLHRDPEIW-PEPEAFKPERFSKKNK 423 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 + I P+ + F GPR+CIG F+++ K + +LQ++SF++ Sbjct: 424 DNID-----PYIYMPFGSGPRNCIGMRFALVLIKLAVVEILQQYSFSV 466
>CP4P3_DROME (Q9V559) Probable cytochrome P450 4p3 (EC 1.14.-.-) (CYPIVP3)| Length = 515 Score = 84.7 bits (208), Expect = 2e-16 Identities = 54/162 (33%), Positives = 89/162 (54%), Gaps = 3/162 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETL 530 G++ TS+ L + + +S+YPE QE+ +E+ + N LNKLK + + ET+ Sbjct: 323 GYDTTSIGLMFGLMNMSLYPEEQEKCYQEIQANIDDELNILNIGQLNKLKNLEYFIKETM 382 Query: 529 RLYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 RL+ M R+T + + + L LPKG I + + +HR+ E W D +EF+P RF Sbjct: 383 RLFPSVPAMGRETTRETELSNGLILPKGSQIFVHVFDIHRNPEYW-DSPEEFRPERFLPE 441 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + + + FS G R+CIGQ F+M E K+ + +L++F Sbjct: 442 -NSQNRHTYAYIPFSAGQRNCIGQKFAMQEMKTLMVALLKQF 482
>CP3AR_ONCMY (O42563) Cytochrome P450 3A27 (EC 1.14.14.1) (CYPIIIA27)| Length = 518 Score = 84.7 bits (208), Expect = 2e-16 Identities = 51/175 (29%), Positives = 94/175 (53%), Gaps = 1/175 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 G+E +S +++ Y L+ +L++E+ F ++P AL ++ + VL E+LR Sbjct: 311 GYETSSSTMSFLAYNLATNHHVMTKLQEEIDTVFPNKAPIQYEALMQMDYLDCVLNESLR 370 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY A ++R + + + +PK +++P +HRD E+W D +EFKP RF Sbjct: 371 LYPIAPRLERVAKKTVEINGIVIPKDCIVLVPTWTLHRDPEIW-SDPEEFKPERFSKENK 429 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 + P+ + F GPR+CIG F+++ K + +LQ F+F++ D P+++ Sbjct: 430 ESID-PYTYMPFGAGPRNCIGMRFALIMIKLAMVEILQSFTFSVC-DETEIPLEM 482
>CP139_MYCTU (P63719) Putative cytochrome P450 139 (EC 1.14.-.-)| Length = 430 Score = 84.3 bits (207), Expect = 3e-16 Identities = 57/191 (29%), Positives = 87/191 (45%), Gaps = 3/191 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G+E TS L W++Y L P E EV + G + P + L+ L + V+ ETLRL Sbjct: 235 GYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRL 294 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGIT 347 YSP + R+ + D+ ++ G ++ + HR E+W + EF+PLR+ N Sbjct: 295 YSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAAD 353 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH--APVDIFTL 173 PH + FS G CIG + E LA ++ + L H + L Sbjct: 354 YRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAAL 413 Query: 172 KPKFGLQVFVR 140 +P GL V +R Sbjct: 414 RPWPGLTVEIR 424
>CP139_MYCBO (P63720) Putative cytochrome P450 139 (EC 1.14.-.-)| Length = 430 Score = 84.3 bits (207), Expect = 3e-16 Identities = 57/191 (29%), Positives = 87/191 (45%), Gaps = 3/191 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G+E TS L W++Y L P E EV + G + P + L+ L + V+ ETLRL Sbjct: 235 GYETTSGALAWAIYALLTVPGTWESAASEVARVLGGRVPAADDLSALTYLNGVVHETLRL 294 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KNGIT 347 YSP + R+ + D+ ++ G ++ + HR E+W + EF+PLR+ N Sbjct: 295 YSPGVISARRVLRDLWFDGHRIRAGRLLIFSAYVTHRLPEIW-PEPTEFRPLRWDPNAAD 353 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH--APVDIFTL 173 PH + FS G CIG + E LA ++ + L H + L Sbjct: 354 YRKPAPHEFIPFSGGLHRCIGAVMATTEMTVILARLVARAMLQLPAQRTHRIRAANFAAL 413 Query: 172 KPKFGLQVFVR 140 +P GL V +R Sbjct: 414 RPWPGLTVEIR 424
>CP343_HUMAN (Q9HB55) Cytochrome P450 3A43 (EC 1.14.14.1)| Length = 503 Score = 84.0 bits (206), Expect = 4e-16 Identities = 48/161 (29%), Positives = 91/161 (56%), Gaps = 1/161 (0%) Frame = -1 Query: 700 HENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRL 524 ++ TS L + +Y L+ +P+ Q++L++E+ ++P +AL +++ + MV+ ETLRL Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 + + R D+ + + +PKG+A+++PI +H D + W + ++F P RF Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYW-TEPEKFCPERFSKKNKD 425 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + + + + F GPR+CIG F++ K + LQ FSF Sbjct: 426 SIDL-YRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 465
>CP9E2_BLAGE (Q964T2) Cytochrome P450 9e2 (EC 1.14.-.-) (CYPIXE2)| Length = 533 Score = 83.6 bits (205), Expect = 5e-16 Identities = 61/192 (31%), Positives = 99/192 (51%), Gaps = 7/192 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPN----ALNKLKEMTMVLFE 536 G + S LL + +LL+ P+ Q RL+ E+ + ++ D A++ +K + MV+ E Sbjct: 335 GFDTASTLLCFMSHLLATNPDVQNRLQDEI--DQSLEENDGKLTYEAIHSMKYLDMVVSE 392 Query: 535 TLRLYSPALFMQRKTVADMTVG---SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLR 365 +LRLY PA+F RK V + + S L G A+ IPI +H D + + + ++F P R Sbjct: 393 SLRLYPPAIFTDRKCVKNYRLPMEPSYTLEPGDAVWIPIYAIHHDPKYY-PNPEKFDPER 451 Query: 364 FKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVD 185 F + K P L F GPR+CIG F+++E+K L +L +F+ + P+ Sbjct: 452 FSDENKDNIK-PFTYLPFGSGPRNCIGNRFALMESKIALVHLLCRFNLKV---VSKTPIP 507 Query: 184 IFTLKPKFGLQV 149 I K F + V Sbjct: 508 IKITKKGFNMTV 519
>CP17A_MOUSE (P27786) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 83.6 bits (205), Expect = 5e-16 Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 8/196 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E TS +L W + L PE + +++KE+ + G ++P N L + + E LR Sbjct: 302 GIETTSSVLNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVLR 361 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A L + K D ++G +PK ++I + +H DK W D D F P RF + Sbjct: 362 IRPVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEW-DQPDRFMPERFLDPT 420 Query: 349 TGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD-----YVHAPV 188 P L F GPRSCIG+ + E +AL+LQ+F F +S D V P Sbjct: 421 GSHLITPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDVSDDKQLPCLVGDPK 480 Query: 187 DIFTLKPKFGLQVFVR 140 +F + P F +++ VR Sbjct: 481 VVFLIDP-FKVKITVR 495
>C97B2_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)| Length = 576 Score = 83.6 bits (205), Expect = 5e-16 Identities = 60/192 (31%), Positives = 93/192 (48%), Gaps = 29/192 (15%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE T+ +LTW+V+LL+ P ++ + EV G P +L +L+ + +++ E LRL Sbjct: 354 GHETTAAVLTWAVFLLAQNPSKMKKAQAEVDLVLGTGRPTFESLKELQYIRLIVVEALRL 413 Query: 523 Y-SPALFMQRKTVADMTVGSLK-------LPKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 Y P L ++R +D+ G K +P G + I + +HR W D D+F+P Sbjct: 414 YPQPPLLIRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNLHRSPYFW-DRPDDFEPE 472 Query: 367 RF----KN----GITG-------AAKVPH------GLLAFSMGPRSCIGQNFSMLEAKST 251 RF KN G G A P+ L F GPR C+G F+++E+ Sbjct: 473 RFLVQNKNEEIEGWAGLDPSRSPGALYPNEVISDFAFLPFGGGPRKCVGDQFALMESTVA 532 Query: 250 LALMLQKFSFTL 215 L ++LQ F L Sbjct: 533 LTMLLQNFDVEL 544
>CP136_MYCTU (P95099) Putative cytochrome P450 136 (EC 1.14.-.-)| Length = 492 Score = 83.2 bits (204), Expect = 7e-16 Identities = 53/167 (31%), Positives = 83/167 (49%), Gaps = 1/167 (0%) Frame = -1 Query: 700 HENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLY 521 H+ ++ T Y L+ +PEWQ+R R E + G D +L +L+ + +V+ E++RL Sbjct: 305 HDTSTSTATTMAYQLAAHPEWQQRCRDESDRH-GDGPLDIESLEQLESLDLVMNESIRLV 363 Query: 520 SPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 341 +P + R+TV D + LPKG ++ + HR E+W D F P RF Sbjct: 364 TPVQWAMRQTVRDTELLGYYLPKGTNVIAYPGMNHRLPEIWTDPL-TFDPERFTEPRNEH 422 Query: 340 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS-PDY 203 + + F G CIG F LE K+ L +L+++ LS PDY Sbjct: 423 KRHRYAFTPFGGGVHKCIGMVFDQLEIKTILHRLLRRYRLELSRPDY 469
>C81E1_GLYEC (P93147) Cytochrome P450 81E1 (EC 1.14.13.89) (Isoflavone| 2'-hydroxylase) (P450 91A4) (CYP GE-3) Length = 499 Score = 82.0 bits (201), Expect = 2e-15 Identities = 55/165 (33%), Positives = 91/165 (55%), Gaps = 2/165 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G +++++ L WS+ L +PE ++++ E+ G D + L KL + V+ ETLR Sbjct: 303 GTDSSAVTLEWSMSNLLNHPEVLKKVKDELDTHVGQDRLVDESDLPKLTYLKNVINETLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY+PA L + T + +G K+P+ ++I +HRD E+W +A FKP RF+ Sbjct: 363 LYTPAPLLLPHSTSDECNIGGYKVPQDTIVLINAWAIHRDPELW-TEATTFKPERFEK-- 419 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 G + L+AF MG R+C G+ ++ TLAL++Q F + L Sbjct: 420 KGELEK---LIAFGMGRRACPGEGLAIRAISMTLALLIQCFDWKL 461
>CP46A_MOUSE (Q9WVK8) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 81.6 bits (200), Expect = 2e-15 Identities = 62/190 (32%), Positives = 94/190 (49%), Gaps = 1/190 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 GHE ++ L ++V LS PE RL+ EV + G + D L +L+ ++ VL E+LR Sbjct: 303 GHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLR 362 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY PA R + + +++P ++ +M R + + +D F P RF Sbjct: 363 LYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFG---P 418 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKP 167 GA K FS+G RSCIGQ F+ +E K +A +LQ+ F L P + TLKP Sbjct: 419 GAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKP 478 Query: 166 KFGLQVFVRP 137 + +RP Sbjct: 479 LDPVLCTLRP 488
>CP4C1_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)| Length = 511 Score = 81.3 bits (199), Expect = 3e-15 Identities = 56/196 (28%), Positives = 103/196 (52%), Gaps = 7/196 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETL 530 GH+ TS + W+++LL +PE Q+++ +E+ F +S L +K + V+ E+L Sbjct: 315 GHDTTSAGICWALFLLGSHPEIQDKVYEELDHIFQGSDRSTTMRDLADMKYLERVIKESL 374 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKPLRF 362 RL+ F+ R D +G +P G + + I +HR+++ + + + D F P R Sbjct: 375 RLFPSVPFIGRVLKEDTKIGDYLVPAGCMMNLQIYHVHRNQDQYPNPEAFNPDNFLPERV 434 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF-TLSPDYVHAPVD 185 A + P+ + FS GPR+CIGQ F+ LE K+ L+ +L+ F ++ ++ Sbjct: 435 ------AKRHPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMN 488 Query: 184 IFTLKPKFGLQVFVRP 137 L+P+ G++V + P Sbjct: 489 ELILRPESGIKVELIP 504
>CP46A_HUMAN (Q9Y6A2) Cytochrome p450 46A1 (EC 1.14.13.98) (Cholesterol| 24-hydroxylase) (CH24H) Length = 500 Score = 81.3 bits (199), Expect = 3e-15 Identities = 62/190 (32%), Positives = 94/190 (49%), Gaps = 1/190 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 GHE ++ L ++V LS PE RL+ EV + G + D L +L+ ++ VL E+LR Sbjct: 303 GHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLR 362 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 LY PA R + + +++P ++ +M R + + +D F P RF Sbjct: 363 LYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGR-MDTYFEDPLTFNPDRFG---P 418 Query: 346 GAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKP 167 GA K FS+G RSCIGQ F+ +E K +A +LQ+ F L P + TLKP Sbjct: 419 GAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKP 478 Query: 166 KFGLQVFVRP 137 + +RP Sbjct: 479 LDPVLCTLRP 488
>C4D14_DROME (O46051) Probable cytochrome P450 4d14 (EC 1.14.-.-) (CYPIVD14)| Length = 507 Score = 81.3 bits (199), Expect = 3e-15 Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 3/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 GH+ T+ + ++ YLL+ +PE Q R+ +EV G P L +LK + V+ E+ Sbjct: 316 GHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKES 375 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LRL+ + R D + +P ++I I RD + + D ++F P RF Sbjct: 376 LRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFSME 434 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 G P FS GPR+CIGQ F+MLE KST++ M++ F + V PV L Sbjct: 435 RKGEIS-PFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQ-PVLNVIL 492 Query: 172 KPKFGLQVFVRP 137 + G+ ++P Sbjct: 493 RSTTGINCGLKP 504
>CP317_DROME (Q9V776) Probable cytochrome P450 317a1 (EC 1.14.-.-)| (CYPCCCXVIIA1) Length = 518 Score = 80.9 bits (198), Expect = 4e-15 Identities = 53/169 (31%), Positives = 92/169 (54%), Gaps = 5/169 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPD--PNALNKLKEMTMVLFETL 530 G+E T+ L++ +Y L+++PE Q R+R+EV K + L M V+ ETL Sbjct: 321 GYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETL 380 Query: 529 RLYSPALFMQRKTVADMTVGSLK---LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK 359 R++ ++ R+T+ D V L K + ++IP +H D +++ D +EFKP R+ Sbjct: 381 RMHPITPYILRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIY-PDPEEFKPDRW- 438 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 212 +G + + F +G RSCIG F+ L+ + LAL+L ++ F+L+ Sbjct: 439 SGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLN 487
>CP52C_CANMA (P16496) Cytochrome P450 52A3 (EC 1.14.14.-) (CYPLIIA3)| (Alkane-inducible P450-ALK1-A) (P450-CM1) (CYP52A3-A) (Cytochrome P-450ALK) Length = 522 Score = 80.9 bits (198), Expect = 4e-15 Identities = 60/202 (29%), Positives = 95/202 (47%), Gaps = 15/202 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVL 542 G + T+ LL+++++ L+ P+ +LR+EV FG+ L K + + VL Sbjct: 320 GRDTTAGLLSFAMFELARNPKIWNKLREEVEVNFGLGDEARVDEISFETLKKCEYLKAVL 379 Query: 541 FETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDD 389 ETLR+Y R D T+ + +PKG ++V + HR K+ +G+D Sbjct: 380 NETLRMYPSVPINFRTATRDTTLPRGGGKDGNSPIFVPKGSSVVYSVYKTHRLKQFYGED 439 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 A EF+P R+ T K+ L F+ GPR C+GQ F++ EA +A + Q F S Sbjct: 440 AYEFRPERWFEPST--RKLGWAYLPFNGGPRICLGQQFALTEASYVIARLAQMFEHLESK 497 Query: 208 DYVHAPVDIFTLKPKFGLQVFV 143 D + P L VF+ Sbjct: 498 DETYPPNKCIHLTMNHNEGVFI 519
>CP52V_CANAP (P43083) Cytochrome P450 52E1 (EC 1.14.14.-) (CYPLIIE1)| Length = 519 Score = 80.5 bits (197), Expect = 5e-15 Identities = 57/182 (31%), Positives = 89/182 (48%), Gaps = 14/182 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG---MQSPDPNALNKLKEMTMVLFET 533 G + T+ LL++ Y L YPE LR+ VL EFG +++P L + K + V+ E Sbjct: 313 GRDTTAGLLSFITYYLGAYPEVYAELREAVLSEFGSTDVETPTFEQLKQCKVLQNVIREV 372 Query: 532 LRLYSPALFMQRKTVADMTVGS---------LKLPKGIAIVIPIPIMHRDKEVWGDDADE 380 LRL+ R+ + D + + + +PKG + M R ++WG DA Sbjct: 373 LRLHPNVPLNFRQAIVDTKLPTGGGPNGDQPVFVPKGQNVFYSTYSMQRRTDIWGPDATT 432 Query: 379 FKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS--FTLSPD 206 F+P R+ N A + F+ GPR C+GQ F++ EA T+ + Q+FS L PD Sbjct: 433 FRPDRW-NEPREALASGWDYIPFNGGPRICLGQQFALTEASYTIVRICQEFSRIEVLHPD 491 Query: 205 YV 200 + Sbjct: 492 VI 493
>CP52F_CANTR (P30608) Cytochrome P450 52A6 (EC 1.14.14.-) (CYPLIIA6)| (Alkane-inducible P450-ALK3) Length = 524 Score = 80.1 bits (196), Expect = 6e-15 Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 15/186 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVL 542 G + T+ LL+++++ L+ +PE +LR+E+ FG+ +L + + + +L Sbjct: 322 GRDTTAGLLSFAMFELARHPEIWSKLREEIEVNFGVGEESRVEEITFESLKRCEYLKAIL 381 Query: 541 FETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDD 389 ETLR+Y R D T+ + +PKG + + HR +E +G D Sbjct: 382 NETLRMYPSVPVNSRTATRDTTLPRGGGPNGTDPIFIPKGSTVAYIVYKTHRLEEYYGKD 441 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 AD+F+P R+ T K+ + F+ GPR C+GQ F++ EA + ++Q F SP Sbjct: 442 ADDFRPERWFEPST--KKLGWAYVPFNGGPRICLGQQFALTEASYVITRLVQMFETVSSP 499 Query: 208 DYVHAP 191 V P Sbjct: 500 PDVEYP 505
>C6A13_DROME (Q9V4U9) Probable cytochrome P450 6a13 (EC 1.14.-.-) (CYPVIA13)| Length = 493 Score = 80.1 bits (196), Expect = 6e-15 Identities = 53/168 (31%), Positives = 90/168 (53%), Gaps = 4/168 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETL 530 G + +S +++ +Y L++ P+ QERLR EVL Q +++ ++ + V+ ETL Sbjct: 296 GFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETL 355 Query: 529 RLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 R Y + R++ + + +L L G I+IP+ +H D E++ D ++F P RF+ Sbjct: 356 RKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELY-PDPEKFDPSRFEP 414 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 212 A+ P L F GPR+CIG+ F L+ K L +L+ F F+ S Sbjct: 415 EEI-KARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRS 461
>C97B1_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2)| Length = 552 Score = 79.7 bits (195), Expect = 8e-15 Identities = 59/184 (32%), Positives = 90/184 (48%), Gaps = 29/184 (15%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE T+ +LTW+V+LL+ P+ ++ + EV GM P L KL+ + +++ ETLRL Sbjct: 363 GHETTAAVLTWAVFLLAQNPDKMKKAQAEVDLVLGMGKPTFELLKKLEYIRLIVVETLRL 422 Query: 523 Y-SPALFMQRKTVADMTVGSLK-------LPKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 Y P L ++R D+ G K +P G + I + +HR W D ++F+P Sbjct: 423 YPQPPLLIRRSLKPDVLPGGHKGDKDGYTIPAGTDVFISVYNLHRSPYFW-DRPNDFEPE 481 Query: 367 RF--------KNGITG-------AAKVPH------GLLAFSMGPRSCIGQNFSMLEAKST 251 RF G G A P+ L F GPR C+G F+++E ST Sbjct: 482 RFLVQNNNEEVEGWAGFDPSRSPGALYPNEIISDFAFLPFGGGPRKCVGDQFALME--ST 539 Query: 250 LALM 239 +AL+ Sbjct: 540 VALV 543
>C505_FUSOX (Q9Y8G7) Bifunctional P-450:NADPH-P450 reductase (Fatty acid| omega-hydroxylase) (P450foxy) [Includes: Cytochrome P450 505 (EC 1.14.14.1); NADPH--cytochrome P450 reductase (EC 1.6.2.4)] Length = 1066 Score = 79.7 bits (195), Expect = 8e-15 Identities = 59/183 (32%), Positives = 92/183 (50%), Gaps = 4/183 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE TS L++++Y L PE +++KEV + G L KL ++ VL ETLRL Sbjct: 267 GHETTSGTLSFAMYQLLKNPEAYSKVQKEVDEVVGRGPVLVEHLTKLPYISAVLRETLRL 326 Query: 523 YSPALFMQRKTVADMTVGSLKL-PKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGIT 347 SP + + D +G L KG + + H D V+G+DAD+F P R + Sbjct: 327 NSPITAFGLEAIDDTFLGGKYLVKKGEIVTALLSRGHVDPVVYGNDADKFIPERMLDDEF 386 Query: 346 GA--AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS-PDYVHAPVDIFT 176 + P+ F G R+CIG+ F+ E+ + ++ Q F+FT++ P+Y T Sbjct: 387 ARLNKEYPNCWKPFGNGKRACIGRPFAWQESLLAMVVLFQNFNFTMTDPNYALEIKQTLT 446 Query: 175 LKP 167 +KP Sbjct: 447 IKP 449
>C6A14_DROME (Q9V4U7) Probable cytochrome P450 6a14 (EC 1.14.-.-) (CYPVIA14)| Length = 509 Score = 79.3 bits (194), Expect = 1e-14 Identities = 58/175 (33%), Positives = 91/175 (52%), Gaps = 11/175 (6%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNK--LKEMT---MVLF 539 G E +S ++ +Y L++ P+ Q+RLR+E+ E + + D LN L +MT VL Sbjct: 314 GFETSSSTMSLCLYELALQPDIQQRLREEI--ESVLANVDGGELNYDVLAQMTYLDQVLS 371 Query: 538 ETLRLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEF 377 ETLR + + R+T D + + L KGI +IP+ +H D E++ + D F Sbjct: 372 ETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRF 431 Query: 376 KPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 212 P KN + P L F GPR+CIG F ++AK L +L++F F++S Sbjct: 432 DPEEVKN------RHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVS 480
>C4D20_DROME (Q9W011) Probable cytochrome P450 4d20 (EC 1.14.-.-) (CYPIVD20)| Length = 510 Score = 79.0 bits (193), Expect = 1e-14 Identities = 59/196 (30%), Positives = 99/196 (50%), Gaps = 7/196 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA---LNKLKEMTMVLFET 533 G + TS ++ ++Y ++ +PE Q+R+ +E+ + G + P L LK + V+ ET Sbjct: 317 GDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKET 376 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--- 362 +RLY P + R ++ +G +P +I + + HRD + D F+P RF Sbjct: 377 MRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPL-SFRPERFLED 435 Query: 361 -KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVD 185 + G A VP FS GP++CIGQ F++LE K ++ +L +F L P+ Sbjct: 436 QEQGHNTFAYVP-----FSAGPKNCIGQKFAVLEMKVLISKVL-RFYELLPLGEELKPML 489 Query: 184 IFTLKPKFGLQVFVRP 137 F L+ G+ V +RP Sbjct: 490 NFILRSASGINVGLRP 505
>CP6A9_DROME (Q27594) Cytochrome P450 6a9 (EC 1.14.-.-) (CYPVIA9)| Length = 504 Score = 78.6 bits (192), Expect = 2e-14 Identities = 52/172 (30%), Positives = 94/172 (54%), Gaps = 9/172 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETL 530 G E +S + +++Y L+ + + Q+R+RKE + G + + ++ + + V+ ETL Sbjct: 309 GFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETL 368 Query: 529 RLYSPALFMQRKTVADMTV-GSLK--LPKGIAIVIPIPIMHRDKEVWGD----DADEFKP 371 RLY+ + R+ + D V G K + KG+ ++IP MHRD++++ + + D F P Sbjct: 369 RLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSP 428 Query: 370 LRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 R K + L F GPR+CIG F ++A+S LAL++ +F F++ Sbjct: 429 ERVKE------RDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSV 474
>CP2J3_RAT (P51590) Cytochrome P450 2J3 (EC 1.14.14.1) (CYPIIJ3)| Length = 502 Score = 78.6 bits (192), Expect = 2e-14 Identities = 50/164 (30%), Positives = 81/164 (49%), Gaps = 3/164 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNK--LKEMTMVLFETL 530 G E TS L W++ +++YPE QE+++ E+ + G Q PN ++ + V+ E Sbjct: 312 GTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIG-QGRQPNLADRDSMPYTNAVIHEVQ 370 Query: 529 RLYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 R+ + F + R+ D + LPKG I+ + +HRD + W D F P F Sbjct: 371 RIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWA-TPDTFNPEHFLE- 428 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G K L FSMG R+C+G+ + E + ++QKF+F Sbjct: 429 -NGQFKKRESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTF 471
>CP312_DROME (Q9VVN6) Probable cytochrome P450 312a1 (EC 1.14.-.-) (CYPCCCXIIA1)| Length = 510 Score = 78.6 bits (192), Expect = 2e-14 Identities = 49/164 (29%), Positives = 86/164 (52%), Gaps = 3/164 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFET 533 G + T+ L + +Y ++++PE Q+R R+EV G +P ++ +++++ + + ET Sbjct: 317 GFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKET 376 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LR+Y RK A+ T+ +PKG ++I M R K+ + D FKP R+ G Sbjct: 377 LRMYPSGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPM-VFKPDRWAIG 435 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + + F G RSC+GQ ++M+ K LA +L+ F F Sbjct: 436 AEPKIEAT-TFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLF 478
>CP2J2_HUMAN (P51589) Cytochrome P450 2J2 (EC 1.14.14.1) (CYPIIJ2) (Arachidonic| acid epoxygenase) Length = 502 Score = 78.2 bits (191), Expect = 2e-14 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 2/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E TS L W++ +++YPE QE+++ E+ + G Q P A + V+ E R Sbjct: 312 GTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQR 371 Query: 526 LYS-PALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + + L + R+ D T+ LPKG I+ + +HRD W D F P F Sbjct: 372 MGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWA-TPDTFNPDHFLE-- 428 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G K + FS+G R+C+G+ + E ++QKF+F Sbjct: 429 NGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTF 471
>CP52K_CANMA (Q12589) Cytochrome P450 52A11 (EC 1.14.14.-) (CYPLIIA11)| (Alkane-inducible P450-ALK8) Length = 519 Score = 78.2 bits (191), Expect = 2e-14 Identities = 60/191 (31%), Positives = 97/191 (50%), Gaps = 17/191 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA------LNKLKE-MTMV 545 G + T+ LL+++V+ L PE +LR+E+ +FG+ PD L KL E + V Sbjct: 316 GRDTTAGLLSFAVFELGRNPEVWSKLREEIGDKFGLD-PDSRIEDISFELLKLCEYLKAV 374 Query: 544 LFETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGD 392 + ETLRLY R A+ T+ + + KG ++ + + RD++ +G Sbjct: 375 INETLRLYPSVPRNGRFAAANTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGK 434 Query: 391 DADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTL 215 DA+EF+P R+ K+ L F+ GPR C+GQ F++ EA L ++Q F + L Sbjct: 435 DANEFRPERWFE--PEVRKLGWAFLPFNGGPRICLGQQFALTEASYVLVRLIQSFETLEL 492 Query: 214 SPDYVHAPVDI 182 SPD + P + Sbjct: 493 SPDAPYPPAKL 503
>CP52J_CANMA (Q12588) Cytochrome P450 52A10 (EC 1.14.14.-) (CYPLIIA10)| (Alkane-inducible P450-ALK7) Length = 519 Score = 78.2 bits (191), Expect = 2e-14 Identities = 58/190 (30%), Positives = 95/190 (50%), Gaps = 16/190 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVL 542 G + T+ LL+++V+ L PE +LR+E+ +FG+ S L + + VL Sbjct: 316 GRDTTAGLLSFAVFELGRNPEVWSKLRQEIGHKFGLDSYSRVEDISFELLKLCEYLKAVL 375 Query: 541 FETLRLYSP----ALFMQRKTVADMTVGS-----LKLPKGIAIVIPIPIMHRDKEVWGDD 389 ETLRLY A F + T G + + KG ++ + + RD++ +G D Sbjct: 376 NETLRLYPSVPRNARFAAKNTTLPHGGGPDGMSPILVRKGQTVMYSVYALQRDEKYYGKD 435 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTLS 212 A+EF+P R+ K+ L F+ GPR C+GQ F++ EA LA ++Q F + LS Sbjct: 436 ANEFRPERWFE--PEVRKLGWAFLPFNGGPRICLGQQFALTEASYVLARLIQSFETLELS 493 Query: 211 PDYVHAPVDI 182 P+ + P + Sbjct: 494 PEAAYPPAKL 503
>CP4P1_DROME (Q9V558) Cytochrome P450 4p1 (EC 1.14.-.-) (CYPIVP1)| Length = 513 Score = 77.4 bits (189), Expect = 4e-14 Identities = 50/162 (30%), Positives = 89/162 (54%), Gaps = 3/162 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG--MQSPDPNALNKLKEMTMVLFETL 530 G++ TS+ L + + +S+ P+ QE +E+ + + + D LNKLK + + ET Sbjct: 321 GYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSNLDVGQLNKLKYLEYFMKETT 380 Query: 529 RLYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 RL+ M R+ V + + + L LPKG I I + +HR+ + W D +EF+P RF Sbjct: 381 RLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYW-DSPEEFRPERFLPE 439 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + + + FS G R+CIG+ ++M E K+ + ++L++F Sbjct: 440 -NVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQF 480
>CP311_DROME (Q9VYQ7) Probable cytochrome P450 311a1 (EC 1.14.-.-) (CYPCCCXIA1)| Length = 483 Score = 77.4 bits (189), Expect = 4e-14 Identities = 57/188 (30%), Positives = 94/188 (50%), Gaps = 3/188 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G + T+ +++ +Y L+ +PE Q RLRKE+ ++ D +ALN L + ++ E LRL Sbjct: 294 GVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVLRL 353 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 Y+ R+T +G G+ + I + + DKE + D FKP R+ Sbjct: 354 YTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYY-PDPYAFKPERWLPEDGA 412 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---FTL 173 A + FS GP CIG+ +S+L K A ++++F LSP+ AP+ + L Sbjct: 413 VAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE--QAPLRLEAQMVL 470 Query: 172 KPKFGLQV 149 K + G+ V Sbjct: 471 KAQQGINV 478
>C4D21_DROME (Q9VLZ7) Probable cytochrome P450 4d21 (EC 1.14.-.-) (CYPIVD21)| Length = 511 Score = 76.6 bits (187), Expect = 7e-14 Identities = 47/165 (28%), Positives = 93/165 (56%), Gaps = 6/165 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA------LNKLKEMTMVL 542 G + T+ ++ +++ +S +P+ QE + +E++ G PDP+A L +LK + V+ Sbjct: 317 GDDTTTSGVSHALHAISRHPKVQECIYEELVSVLG---PDPDASVTQTKLLELKYLDCVI 373 Query: 541 FETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 ET+RL+ P + R D+ +G + +P +I++ ++RD E + D FKP R+ Sbjct: 374 KETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPL-VFKPERW 432 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + T + P + FS GP++CIGQ F+ L+ K+ ++ +++ + Sbjct: 433 MDMKTTSNTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHY 477
>CP4E3_DROME (Q9VL92) Cytochrome P450 4e3 (EC 1.14.-.-) (CYPIVE3)| Length = 526 Score = 76.6 bits (187), Expect = 7e-14 Identities = 47/162 (29%), Positives = 86/162 (53%), Gaps = 3/162 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM---QSPDPNALNKLKEMTMVLFET 533 GH+ T+ +++SVYLLS +P+ Q +L +E + G +S + K+K + + + E Sbjct: 308 GHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEA 367 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 R+Y F+ R D + +PKG + + + ++ + ++ D F+P RF+ Sbjct: 368 QRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIF-KDPHHFRPERFEE- 425 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 P L FS GPR+CIGQ F++LE K+ ++ +++ F Sbjct: 426 ---EKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
>CP17A_RAT (P11715) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 507 Score = 76.6 bits (187), Expect = 7e-14 Identities = 51/169 (30%), Positives = 84/169 (49%), Gaps = 3/169 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ +L W + L PE +++++KE+ + G ++P N + L + + E LR Sbjct: 302 GIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLR 361 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K D ++G +PK +V+ + +H D+ W D D+F P RF + Sbjct: 362 IRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEW-DQPDQFMPERFLDPT 420 Query: 349 TGAAKVP-HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 P L F GPRSCIG+ + E AL+LQ+F +S D Sbjct: 421 GSHLITPTQSYLPFGAGPRSCIGEALARQELFVFTALLLQRFDLDVSDD 469
>C6A17_DROME (Q9V770) Probable cytochrome P450 6a17 (EC 1.14.-.-) (CYPVIA17)| Length = 501 Score = 76.3 bits (186), Expect = 9e-14 Identities = 51/170 (30%), Positives = 91/170 (53%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPD--PNALNKLKEMTMVLFETL 530 G E +S + +++Y L+ + Q++LR+E+ FG + + + ++K + V+ ETL Sbjct: 305 GFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETL 364 Query: 529 RLYSPALFMQRKTVADMTVGSLK--LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 R Y + R T D + K + KG +VIP +H D +++ + + FKP RF + Sbjct: 365 RKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIY-PEPEIFKPERFTD 423 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 AA+ L F GPR+CIG F M++ LA +++ + F++SP+ Sbjct: 424 EEI-AARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPE 472
>CP52E_CANMA (P24458) Cytochrome P450 52A5 (EC 1.14.14.-) (CYPLIIA5)| (Alkane-inducible P450-ALK2-A) (CYP52A3-B) Length = 523 Score = 75.9 bits (185), Expect = 1e-13 Identities = 57/202 (28%), Positives = 93/202 (46%), Gaps = 15/202 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVL 542 G + T+ LL+++++ L+ P+ +LR+E+ FG+ L K + + VL Sbjct: 321 GRDTTAGLLSFAMFELARNPKIWNKLREEIEVNFGLGEEARVDEISFETLKKCEYLKAVL 380 Query: 541 FETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDD 389 ETLR+Y R D T+ + +PKG ++V + HR +E +G D Sbjct: 381 NETLRMYPSVPVNFRTATRDTTLPRGGGKDGTSPIFVPKGSSVVYTVYKTHRLEEYYGKD 440 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 A EF+P R+ T K+ + F+ GPR C+GQ F++ EA + + Q F S Sbjct: 441 AYEFRPERWFEPST--RKLGWAYVPFNGGPRICLGQQFALTEASYVITRLAQMFEHLESK 498 Query: 208 DYVHAPVDIFTLKPKFGLQVFV 143 D + P L VF+ Sbjct: 499 DETYPPNKCIHLTMNHNEGVFI 520
>CP4E1_DROME (Q9V4T5) Probable cytochrome P450 4e1 (EC 1.14.-.-) (CYPIVE1)| Length = 531 Score = 75.9 bits (185), Expect = 1e-13 Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 4/163 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFE 536 GH+ T+ + ++VYLLS +P+ QE+L E G +A ++ +K + + + E Sbjct: 308 GHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKE 367 Query: 535 TLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 RLY F+ R T D + +PKG + + + ++ + V+ D +F+P RF Sbjct: 368 AQRLYPSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVF-KDPHKFQPERFDR 426 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 G P + FS GPR+CIGQ F++LE K+ ++ +++ F Sbjct: 427 EKPG----PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>CP6J1_BLAGE (Q964R1) Cytochrome P450 6j1 (EC 1.14.-.-) (CYPVIJ1)| Length = 501 Score = 74.7 bits (182), Expect = 3e-13 Identities = 49/163 (30%), Positives = 81/163 (49%), Gaps = 4/163 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETL 530 G +S+ LT+++Y LS++ + Q R E+ + E + ++ +K + MV+ ETL Sbjct: 306 GFHTSSMTLTFALYELSVHQDIQTTARTEIKDVLEHHKKKVTYYSIKDMKYLDMVVNETL 365 Query: 529 RLYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 R Y F+ R+ D + L LP G + IP+ +H D + + A +F P RF Sbjct: 366 RKYPAIPFLDRRCQEDYPLTQDLMLPAGTGVYIPVYALHHDSKYFPSPA-KFDPERFSE- 423 Query: 352 ITGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 +PH + F GPR+CIG F ++ K+ L +L F Sbjct: 424 -KNKQNIPHFAYMPFGEGPRNCIGMRFGSMQVKAALIHILSNF 465
>C28D2_DROME (Q9VMT6) Probable cytochrome P450 28d2 (EC 1.14.-.-) (CYPXXVIIID2)| Length = 501 Score = 74.7 bits (182), Expect = 3e-13 Identities = 50/173 (28%), Positives = 86/173 (49%), Gaps = 8/173 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G E T+L+L + +L PE Q+++RKE+ G + +++L + ++ETLRL Sbjct: 306 GFETTALVLAHIMLMLGRNPEEQDKVRKEI----GSADLTFDQMSELPHLDACIYETLRL 361 Query: 523 YSPALFMQRKTV-----ADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK 359 +SP + ++ A+ ++ L G + IP+ +H D + + +D FKP RF Sbjct: 362 FSPQVAARKLVTEPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYY-EDPLTFKPERFL 420 Query: 358 NGITGAAKVPHG---LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 G K LAF GPR C G F++ + K+ L +L+ F ++P Sbjct: 421 ESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNP 473
>CP4E2_DROME (Q27606) Cytochrome P450 4e2 (EC 1.14.-.-) (CYPIVE2)| Length = 526 Score = 74.7 bits (182), Expect = 3e-13 Identities = 47/163 (28%), Positives = 91/163 (55%), Gaps = 4/163 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA----LNKLKEMTMVLFE 536 GH+ T+ ++++VYLLS + + Q +L KE + G +A ++++K + + + E Sbjct: 308 GHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKE 367 Query: 535 TLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 R+Y F+ R T D + +PKG + + + ++ +++V+ D +F+P RF+ Sbjct: 368 AQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERFEL 426 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 G P + FS GPR+CIGQ F++LE K+ ++ +++ F Sbjct: 427 EKPG----PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF 465
>CP135_DROME (Q9VGB5) Probable cytochrome P450 313a5 (EC 1.14.-.-)| (CYPCCCXIIIA5) Length = 487 Score = 74.7 bits (182), Expect = 3e-13 Identities = 45/161 (27%), Positives = 87/161 (54%), Gaps = 4/161 (2%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF---GMQSPDPNALNKLKEMTMVLFETLR 527 + S+ + + L++++P++Q+ + +E+ + F G L KL ++ VL ET+R Sbjct: 295 DTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMR 354 Query: 526 LYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L + R+T + + + +P+G+ ++I I HR+K++WG A+ F P F Sbjct: 355 LIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPE- 413 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 A+ P+ L FS G ++C+G S++ AK LA +L+ + Sbjct: 414 NKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNY 454
>CP17A_MESAU (P70687) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 511 Score = 73.9 bits (180), Expect = 4e-13 Identities = 50/170 (29%), Positives = 88/170 (51%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ +L+W + L PE +++++KE+ + G ++P N N L + + E LR Sbjct: 303 GIETTASVLSWIIAFLLHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + + +DM++G +PK ++I + +H ++ W D D F P RF + Sbjct: 363 IRPVAPMLIPHRANSDMSIGEFSIPKFTPVIINLWALHHSEKEW-DQPDRFMPERFLDP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 TG+ + L L F G RSCIG+ + E +A +LQ+F + D Sbjct: 421 TGSHLITPSLSYLPFGAGARSCIGEVLARQELFLFMAHLLQRFDLDVPDD 470
>C4G15_DROME (Q9VYY4) Cytochrome P450 4g15 (EC 1.14.-.-) (CYPIVG15)| Length = 574 Score = 73.9 bits (180), Expect = 4e-13 Identities = 56/200 (28%), Positives = 101/200 (50%), Gaps = 11/200 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFET 533 GH+ T+ ++ + L+ I+ + Q+R+ E+ FG S P EM + L ET Sbjct: 380 GHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFG-DSQRPATFQDTLEMKYLERCLMET 438 Query: 532 LRLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKP 371 LR+Y P + R+ D+ + G+ +P+G + + ++HR+ +V+ + D D F P Sbjct: 439 LRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLP 498 Query: 370 LRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF--TLSPDYVH 197 R N + + + FS GPRSC+G+ ++ML+ K L+ +L+ + L+ Sbjct: 499 ERQAN------RHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFK 552 Query: 196 APVDIFTLKPKFGLQVFVRP 137 DI LK + G +V ++P Sbjct: 553 LQADII-LKREEGFRVRLQP 571
>CP27A_RABIT (P17177) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 535 Score = 73.9 bits (180), Expect = 4e-13 Identities = 56/172 (32%), Positives = 84/172 (48%), Gaps = 6/172 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + TS LTW++Y LS PE Q LRKEV+ Q P + + VL ETLR Sbjct: 339 GVDTTSNTLTWALYHLSKNPEIQAALRKEVVGVVAAGQVPQHKDFAHMPLLKAVLKETLR 398 Query: 526 LYSPALFMQRKTVAD--MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-KN 356 LY P + + + D + VG PK V + RD + + D F P R+ + Sbjct: 399 LY-PVIPANSRIIVDKEIEVGGFLFPKNTQFVFCHYVTSRDPSTFSEP-DTFWPYRWLRK 456 Query: 355 GITGAAKVPH--GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 G +K H G + F G R+C+G+ + LE + LA ++Q++ L+P+ Sbjct: 457 GQPETSKTQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQRYELMLAPE 508
>CP6L1_BLAGE (Q9GQM9) Cytochrome P450 6l1 (EC 1.14.-.-) (CYPVIL1)| Length = 503 Score = 73.9 bits (180), Expect = 4e-13 Identities = 47/161 (29%), Positives = 81/161 (50%), Gaps = 4/161 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP--NALNKLKEMTMVLFETL 530 G E TS + +++Y L+++PE Q+RLR E+ + + K+ + MV+ E L Sbjct: 299 GFETTSSAMAFAMYELALHPEIQDRLRTEIQEVTACHGGQVTYEGVKKMSYLDMVVSEVL 358 Query: 529 RLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 R Y P F+ R + D + + + KG I + + +HRD ++ D ++F P RF N Sbjct: 359 RKYPPMSFIDRVCLHDYHIPGTDVVIEKGTPIFVSLLGLHRD-SIFYPDPEDFNPERF-N 416 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQ 233 + P + F GPR+CIG ++ K + ++LQ Sbjct: 417 KEKKSGVHPFSYIPFGDGPRNCIGLRLGLMSVKLVIIMLLQ 457
>CP17A_CHICK (P12394) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 73.9 bits (180), Expect = 4e-13 Identities = 57/192 (29%), Positives = 100/192 (52%), Gaps = 4/192 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ +L W+V L YPE Q+++++E+ ++ G+ + P + L + + E LR Sbjct: 306 GVETTTTVLKWAVLYLLHYPEVQKKIQEEMDQKIGLARHPHLSDRPLLPYLEATISEGLR 365 Query: 526 L--YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 + SP L + ++AD ++G +PKG +VI + +H D++ W D +EF P RF + Sbjct: 366 IRPVSP-LLIPHVSLADTSIGEYSIPKGARVVINLWSVHHDEKEW-DKPEEFNPGRFLDE 423 Query: 352 ITGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 P L F G R C+G+ + +E LA +LQ+F+ D + + Sbjct: 424 QGQHIHSPSPSYLPFGAGIRVCLGEVLAKMELFLFLAWVLQRFTLECPQDQ-----PLPS 478 Query: 175 LKPKFGLQVFVR 140 L+ KFG+ + V+ Sbjct: 479 LEGKFGVVLQVQ 490
>C82A1_PEA (Q43068) Cytochrome P450 82A1 (EC 1.14.-.-) (CYPLXXXII) (Fragment)| Length = 544 Score = 73.6 bits (179), Expect = 6e-13 Identities = 61/195 (31%), Positives = 91/195 (46%), Gaps = 6/195 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G + T+ LTW++ LL +P E+L++E+ G + + + +NKL + ++ ETLR Sbjct: 341 GSDTTAGTLTWAMCLLLKHPHVLEKLKEELNTYIGKERCVNESDINKLVYLHAIIKETLR 400 Query: 526 LYSPALFMQ-RKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KN 356 LY PA F R+ D T+G + KG ++ + +HRD VW D EFKP RF + Sbjct: 401 LYPPAPFSSPREFTEDCTIGGYHIKKGTRLMPNLWKIHRDPSVWPDPL-EFKPERFLSTH 459 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS-FTLSPDYVH-APVDI 182 LL F G R C G + + LA L F SP+ + V Sbjct: 460 KDVDVRGQNFELLPFGSGRRMCAGMSLGLHMVHYILANFLHSFEILNPSPESIDVTEVLE 519 Query: 181 FTLKPKFGLQVFVRP 137 F L+V V+P Sbjct: 520 FVTTKATPLEVLVKP 534
>C4AE1_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)| Length = 496 Score = 73.6 bits (179), Expect = 6e-13 Identities = 54/192 (28%), Positives = 98/192 (51%), Gaps = 3/192 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNK---LKEMTMVLFET 533 GH+ T+ +++ +YLLS + Q++L +E+ +G L+ L ++ V+ E+ Sbjct: 305 GHDTTTSAVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKES 364 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LRLY P + R D+ + +P G +V+ + + RD+ ++ D F+P R G Sbjct: 365 LRLYPPIPAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTDPL-VFQPERHL-G 422 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 P+ + FS GPR+CIGQ F++LE K+ + +++ + V + I L Sbjct: 423 EEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPSIKI-VL 481 Query: 172 KPKFGLQVFVRP 137 + K G+ V +RP Sbjct: 482 RSKSGVNVGLRP 493
>C6A23_DROME (Q9V771) Probable cytochrome P450 6a23 (EC 1.14.-.-) (CYPVIA23)| Length = 502 Score = 73.6 bits (179), Expect = 6e-13 Identities = 49/170 (28%), Positives = 90/170 (52%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPD--PNALNKLKEMTMVLFETL 530 G E +S + +++Y L++ + Q++LR E+ + + + ++K + V+ ETL Sbjct: 306 GFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETL 365 Query: 529 RLYSPALFMQRKTVADMTVGSLK--LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 R Y + R T D + K + KG +VIP +H D E++ + ++FKP RF + Sbjct: 366 RKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIY-PEPEKFKPERFTD 424 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 AA+ L F GPR+CIG F +++A LA +++ + F++S + Sbjct: 425 EAI-AARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTE 473
>CP6A1_MUSDO (P13527) Cytochrome P450 6A1 (EC 1.14.14.1) (CYPVIA1)| Length = 509 Score = 73.6 bits (179), Expect = 6e-13 Identities = 55/171 (32%), Positives = 90/171 (52%), Gaps = 8/171 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFET 533 G E +S + +++Y L+ + Q+RLR+EV + F D +AL + + VL ET Sbjct: 306 GFETSSSTMGFALYELAQNQQLQDRLREEVNEVFDQFKEDNISYDALMNIPYLDQVLNET 365 Query: 532 LRLYSPAL--FMQRKTVADMTVG---SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 LR Y + + R+T+ D V LPKG + IP+ +H D E++ + +EF P Sbjct: 366 LRKYPVGVGSALTRQTLNDYVVPHNPKYVLPKGTLVFIPVLGIHYDPELY-PNPEEFDPE 424 Query: 367 RFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 RF + + L F GPR+CIG F ++++ LAL+++ F FT+ Sbjct: 425 RFSPEMV-KQRDSVDWLGFGDGPRNCIGMRFGKMQSRLGLALVIRHFRFTV 474
>CP4E5_DROMT (O44221) Cytochrome P450 4e5, mitochondrial precursor (EC 1.14.-.-)| (CYPIVE5) Length = 522 Score = 73.2 bits (178), Expect = 7e-13 Identities = 46/162 (28%), Positives = 84/162 (51%), Gaps = 3/162 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ---SPDPNALNKLKEMTMVLFET 533 GH+ T+ + ++ Y+LS +PE Q +L +E G + ++ +K + + + E Sbjct: 308 GHDTTTSGVAFAGYILSRFPEEQRKLYEEQQAVMGNELNRDATFQEISAMKYLDLFIKEA 367 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 R+Y F+ R T D + +PKG + + I ++ D V+ ++ F P RF+ Sbjct: 368 QRVYPSVPFIGRYTDKDYNIHGTIMPKGTTLNLGIIVLGYDDRVF-EEPHRFYPERFEKQ 426 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 G P + FS GPR+CIGQ F++LE K+ ++ +++ F Sbjct: 427 KPG----PFEYVPFSAGPRNCIGQKFALLELKTVISKLVRTF 464
>CP132_DROME (Q9VGB4) Probable cytochrome P450 313a2 (EC 1.14.-.-)| (CYPCCCXIIIA2) Length = 493 Score = 73.2 bits (178), Expect = 7e-13 Identities = 48/169 (28%), Positives = 86/169 (50%), Gaps = 4/169 (2%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP---DPNALNKLKEMTMVLFETLR 527 E ++ + +++ LL+++PE QE + E+ + F + L +L + VL ETLR Sbjct: 300 ETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLR 359 Query: 526 LYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L F R+T+ D+ + + + +PKG+ I I I R+ + WG +A +F P F Sbjct: 360 LMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEK 419 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY 203 + P+ + FS G R+CIG + ++ +K L +L+ + S Y Sbjct: 420 I-HDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPY 467
>CP2J6_MOUSE (O54750) Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic| acid epoxygenase) Length = 501 Score = 72.8 bits (177), Expect = 1e-12 Identities = 46/163 (28%), Positives = 75/163 (46%), Gaps = 2/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G E TS L W++ +++YPE QE+++ E+ + G + A + T + +R Sbjct: 311 GTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVRR 370 Query: 523 YSP--ALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L + R+ D + LPKG ++ + +HRD + W D F P F Sbjct: 371 MGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWA-TPDVFNPEHFLE-- 427 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G K L FSMG R+C+G+ + E ++QKF+F Sbjct: 428 NGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTF 470
>CP133_DROME (Q9VGB3) Probable cytochrome P450 313a3 (EC 1.14.-.-)| (CYPCCCXIIIA3) Length = 492 Score = 72.8 bits (177), Expect = 1e-12 Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 4/169 (2%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTM---VLFETLR 527 E T + ++ LL+++PE Q+ + +E+ + F + + L+ M V+ ETLR Sbjct: 300 ETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLR 359 Query: 526 LYSPALFMQRKTVADMTVGS-LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L F R+T+ D + S + +PKG+ I I I HR+++ WG D F P F Sbjct: 360 LIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPD- 418 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY 203 + P+ + FS G R+CIG + ++ +K L+ +L+ + S Y Sbjct: 419 NVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKVSTSFRY 467
>CP52B_CANTR (P30607) Cytochrome P450 52A2 (EC 1.14.14.-) (CYPLIIA2)| (Alkane-inducible P450-ALK2) Length = 522 Score = 72.8 bits (177), Expect = 1e-12 Identities = 53/187 (28%), Positives = 93/187 (49%), Gaps = 16/187 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM------QSPDPNALNKLKEMTMVL 542 G + T+ LL++ + L+ P +LR+E+ +FG+ + +L + + VL Sbjct: 319 GRDTTAGLLSFVFFELARTPRVANKLREEIEDKFGLGQDARVEEISFESLKSCEYLKAVL 378 Query: 541 FETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDD 389 E LRLY R + T+ + + KG ++ + HR+K+++G+D Sbjct: 379 NECLRLYPSVPQNFRVATRNTTLPRGGGKDGLSPVLVRKGQTVMYSVYAAHRNKQIYGED 438 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS-FTLS 212 A EF+P R+ T K+ L F+ GPR C+GQ F++ EA +LQ+FS T+ Sbjct: 439 ALEFRPERWFEPET--KKLGWAFLPFNGGPRICLGQQFALTEASYVTVRLLQEFSHLTMD 496 Query: 211 PDYVHAP 191 P+ ++P Sbjct: 497 PNTEYSP 503
>CP17A_PERLE (Q91Z85) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 72.4 bits (176), Expect = 1e-12 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 9/197 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ +L W V L PE +++++KE+ + G ++P N N L + + E LR Sbjct: 301 GIETTTSVLCWIVAFLLHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLR 360 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K D ++G +PK +VI + +H +++ W D D F P RF + Sbjct: 361 IRPVAPMLIPHKANIDSSIGEFTIPKDTHVVINLWALHHNEKEW-DQPDRFMPERFLDA- 418 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL-----SPDYVHAP 191 TG+ + L L F GPR+CIG+ + +A +LQ+F + P P Sbjct: 419 TGSHLITPSLSYLPFGAGPRACIGEVLARQVLFLYVACLLQRFDLDVPDGAPMPCLKGDP 478 Query: 190 VDIFTLKPKFGLQVFVR 140 +F + P F ++V VR Sbjct: 479 KVVFLIDP-FKVKVTVR 494
>C6A21_DROME (Q9V774) Probable cytochrome P450 6a21 (EC 1.14.-.-) (CYPVIA21)| Length = 504 Score = 72.0 bits (175), Expect = 2e-12 Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 9/172 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETL 530 G E +S + +++Y L+ + Q R+RKE + + + N ++ L + V+ ETL Sbjct: 309 GFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETL 368 Query: 529 RLYSPALFMQRKTVADMTV-GSLK--LPKGIAIVIPIPIMHRDKEVWGD----DADEFKP 371 RLY+ + R+ + D V G K + KG+ ++IP MHRD++++ + + D F P Sbjct: 369 RLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSP 428 Query: 370 LRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 R K + L F GPR+CIG F ++A+ LAL+++ F F++ Sbjct: 429 ERVKE------RDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSV 474
>CP4P2_DROME (Q9V557) Probable cytochrome P450 4p2 (EC 1.14.-.-) (CYPIVP2)| Length = 520 Score = 72.0 bits (175), Expect = 2e-12 Identities = 49/164 (29%), Positives = 91/164 (55%), Gaps = 5/164 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETL 530 G++ TS+ L + + +S+Y QE +E+ + + + + + L+KL + + ET+ Sbjct: 326 GYDTTSIGLVFGLMNMSLYAAEQELCYQEIQEHILDDLSNLNLSQLSKLNYLGYFIKETM 385 Query: 529 RLYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--K 359 RLY M R+T+ + + L LPK I I + +HR+ + W + +EF+P RF + Sbjct: 386 RLYPSIPIMGRQTLQETELENGLILPKRSQINIHVFDIHRNPKYW-ESPEEFRPERFLPQ 444 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 N + + P+ + FS G R+CIGQ ++M E K+ + ++L+ F Sbjct: 445 NCLK---RHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHF 485
>C28D1_DROME (Q9VMT5) Probable cytochrome P450 28d1 (EC 1.14.-.-) (CYPXXVIIID1)| Length = 502 Score = 72.0 bits (175), Expect = 2e-12 Identities = 54/173 (31%), Positives = 87/173 (50%), Gaps = 8/173 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G E T+ +LT ++ L+ P+ Q +LR+E+ G +++L + ETLR+ Sbjct: 307 GFETTAQVLTHTLLFLARNPKEQMKLREEI----GTAELTFEQISELPFTEACIHETLRI 362 Query: 523 YSPALFMQRKTVAD------MTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 +SP L RK V + S+KL G ++IP+ +H D + + ++ FKP RF Sbjct: 363 FSPVL-AARKVVTEPCELTNKNGVSVKLRPGDVVIIPVNALHHDPQYY-EEPQSFKPERF 420 Query: 361 KNGITGAAKV-PHGLL-AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 N GA K GL F GPR C G FS+ + K+ L +++ F ++P Sbjct: 421 LNINGGAKKYRDQGLFFGFGDGPRICPGMRFSLTQIKAALVEIVRNFDIKVNP 473
>CP391_DROME (Q9VQD2) Probable cytochrome P450 309a1 (EC 1.14.-.-) (CYPCCCIXA1)| Length = 529 Score = 72.0 bits (175), Expect = 2e-12 Identities = 46/165 (27%), Positives = 76/165 (46%), Gaps = 6/165 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 G E + +L +Y LS + E QE+LR E+L+ + + +N L + E+LR Sbjct: 333 GFETSGAVLYHMLYSLSEHHEEQEKLRSEILEALASEGQISYDQINNLPYLDQCFNESLR 392 Query: 526 LYSPALFMQRKTVADMTVG-----SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 L +P F R + +L L G+ +++P H D +++ +A EF+P RF Sbjct: 393 LTTPIGFFMRICTKPTQINLGDDKTLDLEPGVTVMVPAYQYHHDNDIY-PEASEFRPDRF 451 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 +NG L F GPR C+G L K+ + +L + Sbjct: 452 ENGAASVLTKRGCFLPFGDGPRICLGMRVGQLSVKTAIVHILSNY 496
>C28C1_DROME (Q9VYT8) Probable cytochrome P450 28c1 (EC 1.14.-.-) (CYPXXVIIIC1)| Length = 505 Score = 72.0 bits (175), Expect = 2e-12 Identities = 53/172 (30%), Positives = 85/172 (49%), Gaps = 7/172 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV-LKEFGMQSPDPNALNKLKEMTMVLFETLR 527 G + TS + + LL P+ Q RL +E+ L G PD +AL L ++ E+LR Sbjct: 301 GLDTTSNSIAHCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLR 360 Query: 526 LYSPALFMQRKTVADMTV-GS-----LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLR 365 +Y + + + + GS LKL G +++PI +H D +++ + D F+P R Sbjct: 361 IYPAGGWASKTCTKEYELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLY-PEPDVFRPER 419 Query: 364 FKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 F +G K L F GPR C+G + AK+ LA ++Q+F +SP Sbjct: 420 FLDGGLKNCKQQGIFLGFGNGPRQCVGMRLGLAMAKAALAAIVQRFEVVVSP 471
>CP27A_RAT (P17178) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 71.6 bits (174), Expect = 2e-12 Identities = 55/171 (32%), Positives = 83/171 (48%), Gaps = 6/171 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETL 530 G + TS LTW++Y LS PE QE L KEV + FG + P + + V+ ETL Sbjct: 338 GVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVVPFG-KVPQNKDFAHMPLLKAVIKETL 396 Query: 529 RLYSPALFMQRK-TVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP---LRF 362 RLY R T + + PK V+ ++ RD V+ + + F+P LR Sbjct: 397 RLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPSVF-PEPESFQPHRWLRK 455 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 + + P G + F G RSC+G+ + LE + L+ ++QK+ LSP Sbjct: 456 REDDNSGIQHPFGSVPFGYGVRSCLGRRIAELEMQLLLSRLIQKYEVVLSP 506
>CP2J1_RABIT (P52786) Cytochrome P450 2J1 (EC 1.14.14.1) (CYPIIJ1) (P-450IB)| Length = 500 Score = 71.6 bits (174), Expect = 2e-12 Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 2/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E TS + W + +++YPE QE++ E+ G Q P + L V+ E R Sbjct: 311 GTETTSDM-RWGLLFMALYPEIQEKVHAEIDSVIGQWQQPSMASRESLPYTNAVIHEVQR 369 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + + L + R+ D T+ LPKG ++ + +H+D E W D F P F Sbjct: 370 MGNILPLNVPREVTVDTTLAGYHLPKGTVVLTNLTALHKDPEEWA-TPDTFNPEHFLE-- 426 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G K + FS+G R+C+G+ + E ++QKF+F Sbjct: 427 NGQFKKKEAFIPFSIGKRACLGEQLAKSELFIFFTSLMQKFTF 469
>CP137_MYCTU (O69653) Putative cytochrome P450 137 (EC 1.14.-.-)| Length = 476 Score = 71.6 bits (174), Expect = 2e-12 Identities = 58/190 (30%), Positives = 89/190 (46%), Gaps = 1/190 (0%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE T+ L W+ LL +P+ R+R E + G ++ T V+ ETLR+ Sbjct: 302 GHETTATTLAWAFDLLLHHPDALRRVRAEAVG--GGEA----------FTTAVINETLRV 349 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 PA R +T+G ++ G IV+ I ++R EV+ + EF+P RF G Sbjct: 350 RPPAPLTARVAAQPLTIGGYRVEAGTRIVVHIIAINRSAEVY-EHPHEFRPERF----LG 404 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPV-DIFTLKP 167 + + F G + C+G NFSM E + L ++L++ FT D V L P Sbjct: 405 TRPQTYAWVPFGGGVKRCLGANFSMRELITVLHVLLREGEFTAVDDEPERIVRRSIMLVP 464 Query: 166 KFGLQVFVRP 137 + G +V RP Sbjct: 465 RRGTRVRFRP 474
>CP2R1_HUMAN (Q6VVX0) Cytochrome P450 2R1 (EC 1.14.14.-) (Vitamin D| 25-hydroxylase) Length = 501 Score = 71.2 bits (173), Expect = 3e-12 Identities = 53/196 (27%), Positives = 95/196 (48%), Gaps = 3/196 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLR 527 G E T+ +L W++ +++YP Q +++KE+ G P + K+ VL E LR Sbjct: 311 GTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLR 370 Query: 526 LYS-PALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + L + T D V +PKG ++ + +H D++ W D + F P RF + Sbjct: 371 FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYW-RDPEVFHPERFLDS- 428 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIF-TL 173 +G L+ FS+G R C+G++ + +E +LQ+F ++H P ++ L Sbjct: 429 SGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF-------HLHFPHELVPDL 481 Query: 172 KPKFGLQVFVRPLDKC 125 KP+ G+ + +P C Sbjct: 482 KPRLGMTLQPQPYLIC 497
>CP120_SYNY3 (Q59990) Putative cytochrome P450 120 (EC 1.14.-.-)| Length = 444 Score = 71.2 bits (173), Expect = 3e-12 Identities = 55/190 (28%), Positives = 85/190 (44%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE + L+ LL + + +ER+R+E K Q L K+ + VL E LRL Sbjct: 255 GHETLTSALSSFCLLLGQHSDIRERVRQEQNKLQLSQELTAETLKKMPYLDQVLQEVLRL 314 Query: 523 YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITG 344 P R+ + D PKG + I H D +++ D ++F P RF + Sbjct: 315 IPPVGGGFRELIQDCQFQGFHFPKGWLVSYQISQTHADPDLY-PDPEKFDPERFTPDGSA 373 Query: 343 AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTLKPK 164 P + F G R C+G+ F+ LE K ++Q+F +TL P V + +PK Sbjct: 374 THNPPFAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPK 433 Query: 163 FGLQVFVRPL 134 L+V + L Sbjct: 434 DNLRVKLHSL 443
>CP6A2_DROME (P33270) Cytochrome P450 6a2 (EC 1.14.-.-) (CYPVIA2) (P450-B1)| Length = 506 Score = 71.2 bits (173), Expect = 3e-12 Identities = 49/164 (29%), Positives = 84/164 (51%), Gaps = 5/164 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPN--ALNKLKEMTMVLFETL 530 G E +S +++ +Y L+ + Q+RLR E+ Q ++ + + V+ ETL Sbjct: 311 GFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETL 370 Query: 529 RLYSPALFMQRKTVADMTVGS---LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK 359 RLY+ ++RK + D V L + KG ++IP HRD++++ + + F P RF Sbjct: 371 RLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLY-PNPETFDPERFS 429 Query: 358 NGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 AA+ L F GPR+CIG F ++A+ LA ++ +F Sbjct: 430 PEKV-AARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRF 472
>CP52L_DEBHA (Q9Y757) Cytochrome P450 52A12 (EC 1.14.14.-) (Alkane hydroxylase| 1) (Alkane-inducible p450alk 1) (DH-ALK2) Length = 519 Score = 71.2 bits (173), Expect = 3e-12 Identities = 52/186 (27%), Positives = 92/186 (49%), Gaps = 15/186 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG------MQSPDPNALNKLKEMTMVL 542 G + T+ LL+++ Y L+ P+ +L++E+ ++FG ++ +L K + + +L Sbjct: 317 GRDTTAGLLSFTFYELARNPQVWLKLKEEIYEKFGKGDDARLEDITFESLKKCEYLKALL 376 Query: 541 FETLRLYS--PALFMQRKTVADMTVGS-------LKLPKGIAIVIPIPIMHRDKEVWGDD 389 E LRLY P F + + G + + KG + + MHRD++ +G D Sbjct: 377 NEVLRLYPSVPQNFRVAQKDTSLPRGGGPNRDQPIFIAKGQTVTYTVYAMHRDEQFYGKD 436 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 ++ F+P R+ T K+ L F+ GPR C+GQ F++ EA +A + Q F S Sbjct: 437 SEVFRPERWFEPET--RKLGWAFLPFNGGPRICLGQQFALTEASYVIARLAQLFPNLASH 494 Query: 208 DYVHAP 191 D + P Sbjct: 495 DDEYPP 500
>CP17A_ORYLA (P70085) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 517 Score = 71.2 bits (173), Expect = 3e-12 Identities = 50/186 (26%), Positives = 97/186 (52%), Gaps = 3/186 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ +L W++ L YPE Q+++++E+ ++ G+ + P + L + + E LR Sbjct: 312 GVETTTTVLKWAITYLIHYPEVQKQIQEELDRKVGVDRPPQLSDRGSLPFLEATIREVLR 371 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A L + ++D ++G + KG +VI + +H D++ W + D F P RF + Sbjct: 372 IRPVAPLLIPHVALSDTSLGDFTVRKGTRVVINLWSLHHDEKEW-TNPDLFNPGRFLSAD 430 Query: 349 TGAAKVP-HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 + +P L F G R C+G+ + +E L+ +LQ+F+ ++ P + +L Sbjct: 431 GSSLTLPSSSYLPFGAGLRVCLGEALAKMELFLFLSWILQRFTLSVPPSQ-----SLPSL 485 Query: 172 KPKFGL 155 + KFG+ Sbjct: 486 EGKFGV 491
>CP52A_CANTR (P10615) Cytochrome P450 52A1 (EC 1.14.14.-) (CYPLIIA1)| (Alkane-inducible P450-ALK1) Length = 543 Score = 71.2 bits (173), Expect = 3e-12 Identities = 50/174 (28%), Positives = 85/174 (48%), Gaps = 15/174 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM------QSPDPNALNKLKEMTMVL 542 G + T+ LL++ + LS PE +LR+E+ +FG+ + L + + V+ Sbjct: 337 GRDTTAGLLSFLFFELSRNPEIFAKLREEIENKFGLGQDARVEEISFETLKSCEYLKAVI 396 Query: 541 FETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDD 389 ETLR+Y R + T+ + + KG ++ I HRDK+++G+D Sbjct: 397 NETLRIYPSVPHNFRVATRNTTLPRGGGEGGLSPIAIKKGQVVMYTILATHRDKDIYGED 456 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 A F+P R+ T K+ + F+ GPR C+GQ F++ EA +LQ+F Sbjct: 457 AYVFRPERWFEPET--RKLGWAYVPFNGGPRICLGQQFALTEASYVTVRLLQEF 508
>CP27A_HUMAN (Q02318) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 531 Score = 71.2 bits (173), Expect = 3e-12 Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + TS LTW++Y LS PE QE L +EV+ Q P + + VL ETLR Sbjct: 336 GVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLR 395 Query: 526 LYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP---LRFKN 356 LY R ++ V PK V ++ RD + + + F+P LR Sbjct: 396 LYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEP-ESFQPHRWLRNSQ 454 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 T + P G + F G R+C+G+ + LE + LA ++QK+ L+P+ Sbjct: 455 PATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPE 504
>CP17A_FELCA (Q9GMC8) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 71.2 bits (173), Expect = 3e-12 Identities = 52/196 (26%), Positives = 97/196 (49%), Gaps = 8/196 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W+V L +P+ ++L++E+ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVRWTVAFLLHHPQLYKKLQEEIDQNIGFSRTPTMSDRNQLILLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + K + D ++G + KG ++I + +H +++ W D+F P RF + Sbjct: 363 IRPVAPTLIPHKAIMDSSIGEFAVDKGTNVIINLWALHHNEKEWYRP-DQFMPERFLDPT 421 Query: 349 TGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS-----PDYVHAPV 188 P L F GPRSC+G++ + E +A +LQ+F + P P Sbjct: 422 RSQLISPSLSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRFDLEVPDDGQLPHLEGNPT 481 Query: 187 DIFTLKPKFGLQVFVR 140 +F + P F ++V VR Sbjct: 482 VVFLIAP-FKVKVKVR 496
>CP2R1_MOUSE (Q6VVW9) Cytochrome P450 2R1 (EC 1.14.14.-) (Vitamin D| 25-hydroxylase) Length = 501 Score = 70.9 bits (172), Expect = 4e-12 Identities = 54/196 (27%), Positives = 92/196 (46%), Gaps = 3/196 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG-MQSPDPNALNKLKEMTMVLFETLR 527 G E T+ +L W++ +++YP Q ++ KE+ G + P K+ VL E LR Sbjct: 311 GTETTTNVLRWAILFMALYPNIQGQVHKEIDLIVGHNRRPSWEYKCKMPYTEAVLHEVLR 370 Query: 526 LYS-PALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + L + T D V +PKG ++ + +H D++ W D D F P RF + Sbjct: 371 FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYW-KDPDMFYPERFLDS- 428 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIF-TL 173 G L+ FS+G R C+G+ + +E +LQ+F ++H P ++ L Sbjct: 429 NGYFTKKEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQF-------HLHFPHELVPNL 481 Query: 172 KPKFGLQVFVRPLDKC 125 KP+ G+ + +P C Sbjct: 482 KPRLGMTLQPQPYLIC 497
>C86A2_ARATH (O23066) Cytochrome P450 86A2 (EC 1.14.-.-)| Length = 553 Score = 70.9 bits (172), Expect = 4e-12 Identities = 57/207 (27%), Positives = 101/207 (48%), Gaps = 16/207 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLK--------EFGMQSPDP---NALNKLKE 557 G + +S+ L+W +L++ +P ++++ +E+ + + +P + +++L Sbjct: 308 GRDTSSVALSWFFWLITTHPTVEDKIVREICSVLIETRGTDVSSWTAEPLEFDEVDRLVY 367 Query: 556 MTMVLFETLRLYSPALFMQRKTVA--DMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDAD 383 + L ETLRLY P++ K V D+ +P G ++ I R K WG+D Sbjct: 368 LKAALSETLRLY-PSVPEDSKHVVNDDILPDGTFVPAGSSVTYSIYAAGRMKSTWGEDCL 426 Query: 382 EFKPLRFKNGITGAAKVPHG---LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 212 EFKP R+ + G V H +AF+ GPR C+G++ + L+ K+ A +L + T++ Sbjct: 427 EFKPERWISPDDGKF-VNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVA 485 Query: 211 PDYVHAPVDIFTLKPKFGLQVFVRPLD 131 P + TL K GL V V D Sbjct: 486 PGHKVEQKMSLTLFMKNGLLVNVHKRD 512
>CP6D4_DROME (Q9VCW1) Probable cytochrome P450 6d4 (EC 1.14.-.-) (CYPVID4)| Length = 515 Score = 70.9 bits (172), Expect = 4e-12 Identities = 56/192 (29%), Positives = 89/192 (46%), Gaps = 7/192 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV----LKEFGMQSPDPNALNKLKEMTMVLFE 536 G E T +++Y L+ YPE +RL+ EV K G + D +LNK++ + + + E Sbjct: 319 GQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYD--SLNKMEFLDLCVQE 376 Query: 535 TLRLYSPALFMQRKTVADMTVGSLK--LPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 T+R Y + R+ D TV +PKG +VI + +H D E + D + + P RF Sbjct: 377 TIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYF-PDPETYDPERF 435 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF-TLSPDYVHAPVD 185 P + F GPR CI Q + +K + +LQ F+ +S + Sbjct: 436 SEESRNYN--PTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFENS 493 Query: 184 IFTLKPKFGLQV 149 L PK G++V Sbjct: 494 GIALIPKHGVRV 505
>C4AA1_DROME (Q9V7G5) Probable cytochrome P450 4aa1 (EC 1.14.-.-) (CYPIVAA1)| Length = 514 Score = 70.9 bits (172), Expect = 4e-12 Identities = 45/161 (27%), Positives = 83/161 (51%), Gaps = 2/161 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQER--LRKEVLKEFGMQSPDPNALNKLKEMTMVLFETL 530 G ++ + ++++LL+ PE Q+R L + E ++P L++++ M M + E L Sbjct: 317 GQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEAL 376 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 RLY + RK ++ + LP G + I HR ++ D ++F+P RF Sbjct: 377 RLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIY-PDPEKFQPERFSPE- 434 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + P+ L FS GPR CIG F+++E K+ ++ +L+ + Sbjct: 435 NSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSY 475
>CPXN_ANASP (P29980) Probable cytochrome P450 110 (EC 1.14.-.-)| Length = 459 Score = 70.5 bits (171), Expect = 5e-12 Identities = 55/193 (28%), Positives = 96/193 (49%), Gaps = 6/193 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 GHE T+ + W+ Y + QE+L++E L G +P+P + +L +T V ETLR+ Sbjct: 262 GHETTATTIAWAFYQILKNVNVQEKLQQE-LDRLG-ANPNPMEIAQLPYLTAVSQETLRM 319 Query: 523 YS--PALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 Y P LF R T + + + +L ++ I ++H ++++ + +F+P RF Sbjct: 320 YPVLPTLF-PRITKSSINIAGYQLEPDTTLMASIYLIHYREDLY-PNPQQFRPERF---- 373 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI---- 182 P + F G R C+G ++LE K +A +L + L+ D PV++ Sbjct: 374 IERQYSPSEYIPFGGGSRRCLGYALALLEIKLVIATVLSNYQLALAED---KPVNVQRRG 430 Query: 181 FTLKPKFGLQVFV 143 FTL P G++V + Sbjct: 431 FTLAPDGGVRVIM 443
>CP6D1_MUSDO (Q27698) Cytochrome P450 6d1 (EC 1.14.-.-) (CYPVID1) (Pyrethroid| resistance cytochrome P450) (Cytochrome P450 Ipr) Length = 516 Score = 70.5 bits (171), Expect = 5e-12 Identities = 50/173 (28%), Positives = 83/173 (47%), Gaps = 8/173 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDP---NALNKLKEMTMVL 542 G E T+ ++++Y L++YPE ++ + EV L+ G++ A+ +K + + + Sbjct: 319 GSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCV 378 Query: 541 FETLRLYSPALFMQRKTVADMTVGSLKL--PKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 ET R Y F+ RK D V KL PK I+I + +HRD + + D ++P Sbjct: 379 METTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPED-YRPE 437 Query: 367 RFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 RF + P + F GPR CI Q ++ +K LA +L F+ P Sbjct: 438 RFAD--ESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMP 488
>C82A3_SOYBN (O49858) Cytochrome P450 82A3 (EC 1.14.-.-) (P450 CP6)| Length = 527 Score = 70.5 bits (171), Expect = 5e-12 Identities = 61/203 (30%), Positives = 94/203 (46%), Gaps = 9/203 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA-LNKLKEMTMVLFETLR 527 G ++T++ LTW++ LL P + ++E+ + G + ++KL + ++ ETLR Sbjct: 324 GTDSTAVTLTWALSLLLRNPLALGKAKEEIDMQIGKDEYIRESDISKLVYLQAIVKETLR 383 Query: 526 LYSPALFMQ-RKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 LY PA F R+ + +G + KG ++ + +HRD VW D EFKP RF Sbjct: 384 LYPPAPFSSPREFTENCILGGYHIKKGTRLIHNLWKIHRDPSVWSDPL-EFKPERFLTTH 442 Query: 349 TGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI-- 182 H LL F G R C G + + TLA +L F L+P PVD+ Sbjct: 443 KDVDLRGHNFELLPFGSGRRVCAGMSLGLNMVHFTLANLLHSFDI-LNPS--AEPVDMTE 499 Query: 181 ---FTLKPKFGLQVFVRPLDKCN 122 FT L++ V+P N Sbjct: 500 FFGFTNTKATPLEILVKPRQSPN 522
>CP6G2_DROME (Q9V675) Probable cytochrome P450 6g2 (EC 1.14.-.-) (CYPVIG2)| Length = 519 Score = 70.5 bits (171), Expect = 5e-12 Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 9/178 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 G E++S + +++Y L+ + Q+RLR+E+ L E G Q + L+ M M+L E Sbjct: 317 GFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVT-LKMIESLEFMQMILLEV 375 Query: 532 LRLYSPALFMQRKTVADMTVG------SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP 371 LR+Y P F+ R+ + +PKG+ + IP +H D + + +F P Sbjct: 376 LRMYPPLPFLDRECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPR-KFLP 434 Query: 370 LRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVH 197 RF P+ + F +GP CIG+ F L+AK L +L+ T S H Sbjct: 435 ERFSPE-NRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPH 491
>C71A8_MENPI (Q42716) Cytochrome P450 71A8 (EC 1.14.-.-)| Length = 502 Score = 70.1 bits (170), Expect = 6e-12 Identities = 47/165 (28%), Positives = 83/165 (50%), Gaps = 2/165 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF-GMQSPDPNALNKLKEMTMVLFETLR 527 G + T+++L W++ L +PE ++L+ EV + + + + K+ + V+ ET+R Sbjct: 309 GTDTTAVVLEWAMTELLRHPEIMKKLQSEVRQVVKDKHNITDDDIEKMHYLKAVMKETMR 368 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 ++P L + R D+ V +P G ++I + RD W D+ ++F+P RF N Sbjct: 369 FHTPIPLLVPRVARNDVEVMGYDVPVGTMVMINAWAIGRDPTSW-DEPEKFRPERFLNSS 427 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 + L+ F G R C G F M + TLA ++QKF + L Sbjct: 428 VDFKGLDFELIPFGAGRRGCPGTTFPMATLEFTLANLMQKFDWEL 472
>C71AM_ARATH (Q9STL1) Cytochrome P450 71A22 (EC 1.14.-.-)| Length = 490 Score = 70.1 bits (170), Expect = 6e-12 Identities = 44/176 (25%), Positives = 86/176 (48%), Gaps = 2/176 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF-GMQSPDPNALNKLKEMTMVLFETLR 527 G + + L+ W++ L PE RL++EV G S + + + + V+ ET+R Sbjct: 293 GTDTSYALMEWAMTELLHRPECLNRLQEEVRTICKGNSSVSEDDIKDMNYLKAVIKETMR 352 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L+ P L + ++ D+ +G +P G ++I + R+ WG DA++F+P R N Sbjct: 353 LHPPLPLMVPHESTQDVRLGDYHIPAGTQVMINAWAIGREAATWGPDAEKFRPERHLNSS 412 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 L+ F G R C +F+++ + TLA ++ ++ + L +Y+ ++ Sbjct: 413 VDFRGHNFELIPFGAGRRICPAISFAVILIEVTLANLVHRYDWRLPEEYIEDQTNV 468
>CP17A_SHEEP (Q29497) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 70.1 bits (170), Expect = 6e-12 Identities = 46/170 (27%), Positives = 87/170 (51%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L +P ++R++ + + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISDRNRLVLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K + D ++G L + KG +V+ + +H +++ W D F P RF + Sbjct: 363 IRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKEW-QQPDLFMPERFLDP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 TG + L L F GPRSC+G+ + E ++ +LQ+F+ + D Sbjct: 421 TGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>C4AC3_DROME (Q9VMS7) Probable cytochrome P450 4ac3 (EC 1.14.-.-) (CYPIVAC3)| Length = 509 Score = 70.1 bits (170), Expect = 6e-12 Identities = 52/163 (31%), Positives = 86/163 (52%), Gaps = 4/163 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETL 530 G++ TS L +++ LL+++ + QER +E+ L E + N+L + V+ E+L Sbjct: 318 GYDTTSTSLIFTLLLLALHADVQERCYEELQDLPE-DIDEVSMFQFNELIHLECVIKESL 376 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KN 356 RL+ A + R + + + L LPK I I I + RD + ++F P RF +N Sbjct: 377 RLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHF-PKPNQFLPERFLPEN 435 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 + + P + FS GPR+CIGQ F +LE K LA +++ F Sbjct: 436 SVN---RHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNF 475
>CP308_DROME (Q9VWR2) Probable cytochrome P450 308a1 (EC 1.14.-.-)| (CYPCCCVIIIA1) Length = 490 Score = 69.7 bits (169), Expect = 8e-12 Identities = 52/179 (29%), Positives = 88/179 (49%), Gaps = 13/179 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLR---KEVLKEFGMQSPDPNALNKLKEMTMVLFET 533 G+E +++LL +++Y L++ + Q RL EV + DP AL +L+ L E Sbjct: 288 GYETSAMLLAFALYELALNEDAQRRLHIELDEVAQRHAGNLIDPVALGELRYSEAALLEA 347 Query: 532 LRLYSPALFMQRK-----TVADMTVGS---LKLPKGIAIVIPIPIMHRDKEVWGDDADEF 377 LRL+ +Q++ T+ D G+ LK+ G +V+P+ +H D ++ ++F Sbjct: 348 LRLHPAMQALQKRCTKTFTLPDQKSGASSELKVHLGTVLVLPVQAIHLDPALY-PAPNQF 406 Query: 376 KPLRFKNGITGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 +P RF N + P G L F GPR C G +L+ K+ L +LQ L+ + Sbjct: 407 RPERFLN------QPPMGCRFLGFGAGPRMCPGMRLGLLQTKAALTTLLQDHCVQLADE 459
>C4AD1_DROME (Q9V4T3) Probable cytochrome P450 4ad1 (EC 1.14.-.-) (CYPIVAD1)| Length = 516 Score = 69.7 bits (169), Expect = 8e-12 Identities = 47/174 (27%), Positives = 89/174 (51%), Gaps = 8/174 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ---SPDPNALNKLKEMTMVLFET 533 GH+ + +++++Y LS + E Q++ +E + FG D L+++ + +++ ET Sbjct: 306 GHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRET 365 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN- 356 LRLY + R + + K+ K +++ + M +++ + DD F+P RF+N Sbjct: 366 LRLYPSVPLIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYF-DDPCTFRPERFENP 424 Query: 355 ----GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 GI VP FS GPR CI + F+M + K+ L+ +L++F + D Sbjct: 425 TGNVGIEAFKSVP-----FSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVD 473
>CP27A_MOUSE (Q9DBG1) Cytochrome P450 27, mitochondrial precursor (EC| 1.14.13.15) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) Length = 533 Score = 69.7 bits (169), Expect = 8e-12 Identities = 55/171 (32%), Positives = 82/171 (47%), Gaps = 6/171 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV--LKEFGMQSPDPNALNKLKEMTMVLFETL 530 G + TS LTW++Y LS PE QE L KEV + FG + P + + V+ ETL Sbjct: 338 GVDTTSNTLTWALYHLSKSPEIQEALHKEVTGVVPFG-KVPQHKDFAHMPLLKAVIKETL 396 Query: 529 RLYSPALFMQRK-TVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP---LRF 362 RLY R T + + PK V+ ++ RD V+ + + F+P LR Sbjct: 397 RLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPSVF-PEPNSFQPHRWLRK 455 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 K P G + F G RSC+G+ + LE + L+ ++QK+ L+P Sbjct: 456 KEADNPGILHPFGSVPFGYGVRSCLGRRIAELEMQLMLSRLVQKYEIALAP 506
>CP1A1_RAT (P00185) Cytochrome P450 1A1 (EC 1.14.14.1) (CYP1A1) (CYPIA1)| (P450-C) (P450MT2) [Contains: Cytochrome P450MT2A; Cytochrome P450MT2B] Length = 524 Score = 69.3 bits (168), Expect = 1e-11 Identities = 46/168 (27%), Positives = 83/168 (49%), Gaps = 3/168 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L P Q ++++E+ G + P + +L + + ET R Sbjct: 322 GFDTITTAISWSLMYLVTNPRIQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFR 381 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T+ D ++ +PKG + + ++ D+E+WGD +EF+P RF Sbjct: 382 HSSFVPFTIPHSTIRDTSLNGFYIPKGHCVFVNQWQVNHDQELWGDP-NEFRPERFLTSS 440 Query: 349 TGAAK-VPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 K + ++ F +G R CIG+ LE LA++LQ+ F +SP Sbjct: 441 GTLDKHLSEKVILFGLGKRKCIGETIGRLEVFLFLAILLQQMEFNVSP 488
>CP6A8_DROME (Q27593) Cytochrome P450 6a8 (EC 1.14.-.-) (CYPVIA8)| Length = 506 Score = 69.3 bits (168), Expect = 1e-11 Identities = 51/169 (30%), Positives = 85/169 (50%), Gaps = 7/169 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPN----ALNKLKEMTMVLFE 536 G E +S + +++Y L+ P+ Q+++R EV E ++ D N LK + VL E Sbjct: 311 GFETSSSTMGFALYELAKNPDIQDKVRAEV--EEVIEQHDQNFTYECTKDLKYLNQVLDE 368 Query: 535 TLRLYSPALFMQRKTVADMTVG---SLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLR 365 TLRLY+ + R V + + G +++IP +H D ++ + EF+P R Sbjct: 369 TLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPF-EFRPER 427 Query: 364 FKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFT 218 F A + L F GPR+CIG F ++A+ LAL+++ F F+ Sbjct: 428 FSPE-ESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFS 475
>CP17A_PANTR (Q8HYN1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 68.9 bits (167), Expect = 1e-11 Identities = 47/169 (27%), Positives = 84/169 (49%), Gaps = 3/169 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W++ L P+ +++L +E+ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L A + + K D ++G + KG ++I + +H +++ W D+F P RF N Sbjct: 363 LRPVAPMLIPHKANVDSSIGEFAVDKGTQVIINLWALHHNEKEW-HQPDQFMPERFLNPA 421 Query: 349 TGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 P L F GPRSCIG+ + E +A +LQ+F + D Sbjct: 422 GTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP17A_HUMAN (P05093) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 68.9 bits (167), Expect = 1e-11 Identities = 47/169 (27%), Positives = 84/169 (49%), Gaps = 3/169 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W++ L P+ +++L +E+ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L A + + K D ++G + KG ++I + +H +++ W D+F P RF N Sbjct: 363 LRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW-HQPDQFMPERFLNPA 421 Query: 349 TGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 P L F GPRSCIG+ + E +A +LQ+F + D Sbjct: 422 GTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP17A_CAVPO (Q64410) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 68.9 bits (167), Expect = 1e-11 Identities = 51/197 (25%), Positives = 94/197 (47%), Gaps = 8/197 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E +S ++ W + L P+ ++++++E+ G ++P + N L + + E LR Sbjct: 303 GVETSSSVVLWVIAFLLHNPQVKKKIQEEIDHNVGFSRTPTFSDRNHLLMLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K D ++G + K +++ + +H +++ W D D+F P RF + Sbjct: 363 IRPVAPILIPHKANTDSSIGEFAIDKDTNVLVNLWALHHNEQEW-DRPDQFMPERFLDPT 421 Query: 349 TGAAKVPHG-LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS-----PDYVHAPV 188 VP L F GPRSC+G+ + E A +LQKF + P P Sbjct: 422 GSQIIVPSSSYLPFGAGPRSCVGEALARQEIFLITAWLLQKFDLEVPEGGQLPSLEGIPK 481 Query: 187 DIFTLKPKFGLQVFVRP 137 +F + P F +++ VRP Sbjct: 482 IVFLIDP-FKVKITVRP 497
>CP11A_ONCMY (Q07217) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) Length = 514 Score = 68.6 bits (166), Expect = 2e-11 Identities = 55/194 (28%), Positives = 95/194 (48%), Gaps = 4/194 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFET 533 G + TS+ L W++Y L+ +P+ QE LR EV QS + L LK + +V L ET Sbjct: 325 GVDTTSITLLWTLYELARHPDLQEELRAEVA--VARQSTQGDMLQMLKMIPLVKGALKET 382 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LRL+ A+ +QR ++ + + +P G + + + M RD +V+ +++ P R+ Sbjct: 383 LRLHPVAVSLQRYITEEIVIQNYHIPCGTLVQLGLYAMGRDPDVF-PRPEKYLPSRWLR- 440 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY-VHAPVDIFT 176 L F GPR C+G+ + E + L ML+ F VH+ ++ Sbjct: 441 ---TENQYFRSLGFGFGPRQCLGRRIAETEMQLFLIHMLENFRVDKQRQVEVHSTFELIL 497 Query: 175 LKPKFGLQVFVRPL 134 L P+ + + ++PL Sbjct: 498 L-PEKPILLTLKPL 510
>CP2L1_PANAR (Q27712) Cytochrome P450 2L1 (EC 1.14.14.1) (CYPIIL1)| Length = 492 Score = 68.6 bits (166), Expect = 2e-11 Identities = 47/164 (28%), Positives = 80/164 (48%), Gaps = 2/164 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G E TS ++ W++ L YPE Q ++++E+ + P +KL + E R Sbjct: 299 GTETTSTMIRWTILYLMKYPEVQAKIQREIDAAVPRGTLPSLEHKDKLAYFEATIHEVHR 358 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + S L + T D + +LPKG ++ + HRD W + +EF P F + Sbjct: 359 IVSLVPLGVSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYW-EKPNEFYPEHFLDDQ 417 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFT 218 K H L+ FS+G R C+G++ + +E L+ +LQ F+F+ Sbjct: 418 GKFVKREH-LVNFSVGRRVCVGESLARMELFVFLSAILQNFTFS 460
>CP2J5_MOUSE (O54749) Cytochrome P450 2J5 (EC 1.14.14.1) (CYPIIJ5) (Arachidonic| acid epoxygenase) Length = 501 Score = 68.6 bits (166), Expect = 2e-11 Identities = 47/163 (28%), Positives = 74/163 (45%), Gaps = 2/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG-MQSPDPNALNKLKEMTMVLFETLR 527 G E TS L W++ +S YPE QE ++ E+ + G + + + V+ E R Sbjct: 311 GTETTSSTLRWALLYMSSYPEIQENVQAEIDRVIGHKRQVSLSDRESMPYTNAVIHEVQR 370 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + + L R+ D LPKG I+ + +HRD + W + F P F Sbjct: 371 MGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATP-EVFNPEHFLEN- 428 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G K L FSMG R+C+G+ + E + ++QKF+F Sbjct: 429 -GQFKKRESFLPFSMGKRACLGEQLAKSELFIFFSALMQKFTF 470
>CP1A2_BALAC (Q3LFT9) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 68.6 bits (166), Expect = 2e-11 Identities = 53/195 (27%), Positives = 96/195 (49%), Gaps = 4/195 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L PE Q ++++E+ G + P + ++L + + ET R Sbjct: 317 GFDPITTAISWSLLYLVTNPEIQRKIQQELDTVIGRARRPRLSDRSQLPYLEAFILETFR 376 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KN 356 S F + T+ D T+ +PK + + I ++ D ++WGD + EF+P RF + Sbjct: 377 HSSFVPFTIPHSTIRDTTLNGFYIPKELCVFINQWQVNHDPKLWGDPS-EFRPERFLTSH 435 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 T + + ++ F MG R CIG+ + E LA++LQ+ F++ P VD Sbjct: 436 DTTISKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPG---VKVD--- 489 Query: 175 LKPKFGLQVFVRPLD 131 L P +GL + P + Sbjct: 490 LTPTYGLTMKPAPCE 504
>CP17A_PAPCY (Q8HYN0) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/170 (28%), Positives = 85/170 (50%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L P+ +++L +E+ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K D ++G + KG ++I + +H +++ W D+F P RF N Sbjct: 363 IRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 G + L L F GPRSCIG+ + E +A +LQ+F + D Sbjct: 421 AGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP17A_MACMU (Q8HYM9) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/170 (28%), Positives = 85/170 (50%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L P+ +++L +E+ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K D ++G + KG ++I + +H +++ W D+F P RF N Sbjct: 363 IRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 G + L L F GPRSCIG+ + E +A +LQ+F + D Sbjct: 421 AGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP17A_MACFA (Q2XVA1) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/170 (28%), Positives = 85/170 (50%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L P+ +++L +E+ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K D ++G + KG ++I + +H +++ W D+F P RF N Sbjct: 363 IRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 G + L L F GPRSCIG+ + E +A +LQ+F + D Sbjct: 421 AGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>CP6G1_DROME (Q9V674) Cytochrome P450 6g1 (EC 1.14.-.-) (CYPVIG1) (Cyp6-like| protein) Length = 524 Score = 68.2 bits (165), Expect = 2e-11 Identities = 53/174 (30%), Positives = 84/174 (48%), Gaps = 14/174 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF--GMQSPDPNALNKLKEMTMVLFETL 530 G E +S +++++Y ++ +PE Q+RLR E+ + G S + L+ + MV+ E L Sbjct: 313 GFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVL 372 Query: 529 RLYSPALFMQR--KTVADMTVGSLK------LPKGIAIVIPIPIMHRDKEVWGD----DA 386 R+Y F+ R ++V SLK L G + IPI +H D + W + D Sbjct: 373 RMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDP 432 Query: 385 DEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 224 + F P KN I A P F GP +CIG +L++K L +L+ S Sbjct: 433 ERFSPANRKN-IVAMAYQP-----FGSGPHNCIGSRIGLLQSKLGLVSLLKNHS 480
>CP313_DROME (Q9VHP4) Probable cytochrome P450 313b1 (EC 1.14.-.-)| (CYPCCCXIIIB1) Length = 502 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 6/163 (3%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA--LNKLKEMTMVLFETLRL 524 E TS L +++ L+++P +QE+L KE++ E S D N L +L+ MV+ E +RL Sbjct: 310 ETTSTALYFTILCLAMHPCYQEKLHKELVTELP-PSGDINLEQLQRLEYTEMVINEAMRL 368 Query: 523 YSPALFMQRKTVADMTV----GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 ++P + R D+ + G +P+G I I I M RD+ VWG + + P Sbjct: 369 FAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNP-DAHF 427 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 G+ + + F+ G R CIG ++ + K LA + + + Sbjct: 428 GLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSY 470
>CP52M_DEBHA (Q9Y758) Cytochrome P450 52A13 (EC 1.14.14.-) (Alkane hydroxylase| 2) (Alkane-inducible p450alk 2) (DH-ALK2) Length = 519 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/175 (27%), Positives = 86/175 (49%), Gaps = 16/175 (9%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG------MQSPDPNALNKLKEMTMVL 542 G + T+ LL+++ + L+ +P +L++E+ + FG + +L K + + V+ Sbjct: 318 GRDTTAGLLSFTFFELARHPRVFNKLKEEIYEAFGKGDDARVSEITFESLKKCEYLKWVM 377 Query: 541 FETLRLYSPALFMQRKTVADMTV----------GSLKLPKGIAIVIPIPIMHRDKEVWGD 392 E LRLY P++ + + T + + KG + + HR +E +G Sbjct: 378 NEMLRLY-PSVPVNFRVATKRTTLPRGGGPDGNSPIYVGKGTTVAYSVYSTHRMEEYYGK 436 Query: 391 DADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 DADEFKP R+ + K+ + F+ GPR C+GQ F++ EA + +LQ F Sbjct: 437 DADEFKPERWAE----SRKLGWAYVPFNGGPRICLGQQFALTEASYIVTRLLQMF 487
>CP17A_CAPHI (Q9N0U7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 68.2 bits (165), Expect = 2e-11 Identities = 46/170 (27%), Positives = 86/170 (50%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L +P ++R++ + + G ++P + N L + + E LR Sbjct: 303 GVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISDRNCLVLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K + D ++G L + KG +V+ + +H +++ W D F P RF + Sbjct: 363 IRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKEW-QQPDLFMPERFLDP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 TG + L L F GPRSC+G+ + E ++ +LQ+F+ + D Sbjct: 421 TGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>CP17A_BOVIN (P05185) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 68.2 bits (165), Expect = 2e-11 Identities = 47/170 (27%), Positives = 86/170 (50%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L +P ++R++ ++ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPTISDRNRLVLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + K V D ++G L + KG +V+ + +H ++ W D F P RF + Sbjct: 363 IRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKEW-QHPDLFMPERFLDP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 TG + L L F GPRSC+G+ + E ++ +LQ+F+ + D Sbjct: 421 TGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>C4AC1_DROME (Q9VMS9) Probable cytochrome P450 4ac1 (EC 1.14.-.-) (CYPIVAC1)| Length = 509 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/161 (31%), Positives = 86/161 (53%), Gaps = 2/161 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNAL--NKLKEMTMVLFETL 530 G++ TS L +++ +L+++ + Q++ +EV + S D + NKL + V+ E+L Sbjct: 318 GYDTTSTCLIFTLLMLALHEDVQKKCYEEV-ENLPEDSDDISMFQFNKLVYLECVIKESL 376 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 R++ F+ R+ V + V + +PK I I I + RD + D F+P RF Sbjct: 377 RMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHF-PKPDLFQPDRFLPEN 435 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 T + P + FS G R+CIGQ F++LE K LA +++ F Sbjct: 436 T-VNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNF 475
>CP392_DROME (P82713) Probable cytochrome P450 309a2 (EC 1.14.-.-) (CYPCCCIXA2)| Length = 538 Score = 68.2 bits (165), Expect = 2e-11 Identities = 55/174 (31%), Positives = 82/174 (47%), Gaps = 8/174 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLR 527 G++ + L ++Y L+ P Q++LR E+L + S D L+ L+ + V++E+LR Sbjct: 341 GYDTSGTALLHALYYLAENPAVQQKLRVEILSCMASEKSLDFEKLSSLQYLEQVIYESLR 400 Query: 526 LYSPALFMQRKTVADMTV-------GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 L S L Q V + SL + G+ I+IP H DK+ + + + FKP Sbjct: 401 LSS--LIPQYTKVCTLPTVIRLSESKSLDVEVGMTIMIPNYQFHHDKQYF-PEPEAFKPE 457 Query: 367 RFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 RF NG L FS GPR C+G +ML KS L +L F D Sbjct: 458 RFDNGAYQELMRKGIFLPFSDGPRICMGVPLAMLTLKSALVHILSNFQVVRGRD 511
>CP1A1_CHACA (Q92039) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 68.2 bits (165), Expect = 2e-11 Identities = 52/187 (27%), Positives = 88/187 (47%), Gaps = 4/187 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + S L+WSV L YP+ QERL +E+ G+ ++P + +K+ + + E R Sbjct: 323 GFDTVSTALSWSVMYLVAYPDIQERLFQEIKDNVGLDRTPLLSDRSKVPYLEAFILELFR 382 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFK--N 356 S F + + D ++ +PK + I ++RD E+W D F P RF N Sbjct: 383 HSSFLPFTIPHCSAKDTSLNGYFIPKDTCVFINQWQINRDPELW-KDPSSFNPDRFLSCN 441 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 G + ++ F MG R CIG+ + E LA+++Q+ F P ++ Sbjct: 442 GTEVNKQEGEKVMVFGMGKRRCIGEVIARNEVYRGLAILIQRLQFH------EMPGELLD 495 Query: 175 LKPKFGL 155 + P++GL Sbjct: 496 MTPEYGL 502
>CP1A3_ONCMY (Q92109) Cytochrome P450 1A3 (EC 1.14.14.1) (CYP1A3) (CYP1A1)| Length = 522 Score = 67.8 bits (164), Expect = 3e-11 Identities = 55/187 (29%), Positives = 88/187 (47%), Gaps = 4/187 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + S L+W+V L YPE QERL +E+ ++ GM ++P + L + + E R Sbjct: 323 GFDTISTALSWAVVYLVAYPETQERLHQELKEKVGMIRTPRLSDKINLPLLEAFILEIFR 382 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T+ D ++ +PK + I ++ D E+W + F P RF + Sbjct: 383 HSSFLPFTIPHCTIKDTSLNGYFIPKDTCVFINQWQVNHDPELW-KEPSSFNPDRFLSAD 441 Query: 349 TGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 G +L F MG R CIG+ E LA++LQ+ F P + P+D Sbjct: 442 GTELNKLEGEKVLVFGMGKRRCIGEAIGRNEVYLFLAILLQRLRFQEKPGH---PLD--- 495 Query: 175 LKPKFGL 155 + P++GL Sbjct: 496 MTPEYGL 502
>CP17A_BISBI (Q9GMC7) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 67.8 bits (164), Expect = 3e-11 Identities = 47/170 (27%), Positives = 86/170 (50%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L +P ++R++ ++ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPAISDRNRLVLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + K V D ++G L + KG +V+ + +H ++ W D F P RF + Sbjct: 363 IRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKEW-QHPDLFMPERFLDP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 TG + L L F GPRSC+G+ + E ++ +LQ+F+ + D Sbjct: 421 TGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDD 470
>C71AO_ARATH (Q9STK9) Cytochrome P450 71A24 (EC 1.14.-.-)| Length = 486 Score = 67.8 bits (164), Expect = 3e-11 Identities = 48/177 (27%), Positives = 85/177 (48%), Gaps = 5/177 (2%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLK----EFGMQSPDPNALNKLKEMTMVLFETL 530 + T LL W++ L + E +RL++EV + G+ D L +K + V+ ETL Sbjct: 294 DTTYTLLEWAMTELLCHHECLDRLQEEVRMVCKDKSGVSEDD---LQDMKYLKAVIKETL 350 Query: 529 RLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 RL+ P L + ++ D+ + +P G ++I + R+ WG DA+EF+P R N Sbjct: 351 RLHPPLPLMVPHESTHDVKLRDYHIPAGTHVMINAWAIGREAATWGPDAEEFRPERHLNS 410 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 L+ F G R C +F+++ + LA ++ +F +TL + D+ Sbjct: 411 YVDYRGQDTELVPFGAGRRICPAISFAVVLDEVVLANLVHQFDWTLPEESTEYQTDV 467
>CP17A_ONCMY (P30437) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 514 Score = 67.8 bits (164), Expect = 3e-11 Identities = 52/186 (27%), Positives = 92/186 (49%), Gaps = 3/186 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E TS +L W++ L +P+ Q+R+++E+ G ++P + L + + E LR Sbjct: 310 GVETTSTVLKWAIAYLIHHPQVQQRIQEELDSVVGGDRTPQLSDRGSLPYLEATIREVLR 369 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A L + D ++G + KG I+I + +H D++ W + + F P RF N Sbjct: 370 IRPVAPLLIPHVAQTDTSIGKFTVRKGARIIINLWSLHHDEKEW-KNPEMFDPGRFLNEE 428 Query: 349 -TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 TG L F G R C+G+ + +E L+ +LQ+ + T+SP + +L Sbjct: 429 GTGLCIPSPSYLPFGAGVRVCLGEALAKMEIFLFLSWILQRLTMTVSPGQ-----PLPSL 483 Query: 172 KPKFGL 155 + KFG+ Sbjct: 484 EGKFGV 489
>STCS_EMENI (Q00714) Probable sterigmatocystin biosynthesis P450 monooxygenase| stcS (EC 1.14.-.-) (Cytochrome P450 59) Length = 505 Score = 67.8 bits (164), Expect = 3e-11 Identities = 58/180 (32%), Positives = 84/180 (46%), Gaps = 13/180 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP--------DPNALNKLKEMTM 548 G + TS L ++ YLLS +PE ++R E + FG D LN+L T Sbjct: 286 GRDTTSSTLLYAFYLLSRHPEALAKVRLEHDQVFGPYHQQVHEKIHQDAKLLNQLPYTTA 345 Query: 547 VLFETLRLYSPALFMQRK----TVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADE 380 VL ETLRL+ P+ M+ + D G + G + +H + W + A+ Sbjct: 346 VLKETLRLFPPSASMREGGPGVEITDDN-GQVYPTAGCNVWTLTVALHHNSAHWAE-AES 403 Query: 379 FKPLRFKNGITGAAKVPHGLL-AFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY 203 F P R+ G G AF GPRSCIGQ +MLE + LA+ L++F ++P Y Sbjct: 404 FIPERWLVGSDHPLYPAKGAWRAFEFGPRSCIGQTLAMLELRVALAMTLREFD--IAPAY 461
>CP6T3_DROME (Q9V676) Probable cytochrome P450 6t3 (EC 1.14.-.-) (CYPVIT3)| Length = 501 Score = 67.4 bits (163), Expect = 4e-11 Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 12/171 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEF-GMQSPDPNALNKLKEMTMVLFETLR 527 G E +S L+ +++Y L+ P+ QERLR E+ + F + + L L + MV E LR Sbjct: 301 GFETSSALMGFTLYELAKAPDIQERLRSELREAFISTATLSYDTLMTLPYLKMVCLEALR 360 Query: 526 LYSPALFMQRKTVADMTVG-SLK------LPKGIAIVIPIPIMHRDKEVWGD----DADE 380 LY A F+ R+ + + G SL+ +P G+ I I +HRD+ W + D + Sbjct: 361 LYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAYISILGLHRDERFWPEPCVFDPER 420 Query: 379 FKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 F P R ++ P + F GP CIG +L+ K + +L+++ Sbjct: 421 FGPERSRH------IHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQY 465
>CP1A1_RABIT (P05176) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450 isozyme| 6) (P-450 PHPAH1) (P450 LM6) Length = 518 Score = 67.4 bits (163), Expect = 4e-11 Identities = 48/168 (28%), Positives = 81/168 (48%), Gaps = 3/168 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L P Q ++++E+ G + P + +L + V+ ET R Sbjct: 322 GFDTVTTAISWSLMYLVTKPRIQRKIQEELDAVVGRARRPRFSDRPQLPYLEAVIMETFR 381 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D ++G +PKG + + + D E+WGD + F+P RF Sbjct: 382 HTSFLPFTIPHSTTRDTSLGGFYIPKGRCVFVNQWQNNHDPELWGDP-EAFRPERFLTPS 440 Query: 349 TGAAK-VPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 K + +L F +G R CIG+ LE LA +LQ+ F++SP Sbjct: 441 GAVDKALTEKVLLFGLGKRKCIGETIGRLEVFLFLATLLQQVEFSVSP 488
>CP52H_CANTR (P30610) Cytochrome P450 52A8 (EC 1.14.14.-) (CYPLIIA8)| (Alkane-inducible P450-ALK5) Length = 517 Score = 67.4 bits (163), Expect = 4e-11 Identities = 54/187 (28%), Positives = 87/187 (46%), Gaps = 16/187 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVL 542 G + ++ LL+++V+ L+ P +LR++V +FG+ +L + + L Sbjct: 314 GRDTSAGLLSFAVFELARNPHIWAKLREDVESQFGLGEQSRIEEITFESLKRCGYLKAFL 373 Query: 541 FETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDD 389 ETLR+Y R + T+ + + KG A+ I H D +GDD Sbjct: 374 NETLRVYPSVPRNFRIATKNTTLPRGGGSDGNSPVLVKKGEAVSYGINSTHLDPVYYGDD 433 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTLS 212 A EF+P R+ T K+ L F+ GPR C+GQ F++ EA L + Q F + L Sbjct: 434 AAEFRPERWNEPST--RKLGWAYLPFNGGPRICLGQQFALTEAGYVLVRLAQSFDTLELK 491 Query: 211 PDYVHAP 191 P V+ P Sbjct: 492 PPVVYPP 498
>CP2D1_RAT (P10633) Cytochrome P450 2D1 (EC 1.14.14.1) (CYPIID1) (P450-DB1)| (P450-CMF1A) (P450-UT-7) (Debrisoquine 4-hydroxylase) Length = 504 Score = 67.4 bits (163), Expect = 4e-11 Identities = 45/165 (27%), Positives = 82/165 (49%), Gaps = 2/165 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG-MQSPDPNALNKLKEMTMVLFETLR 527 G T+ LTW++ L+ +YP+ Q R+++E+ + G ++ P+ + V+ E R Sbjct: 309 GMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQR 368 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 A L + R T D+ V +PKG ++I + + +D+ VW + F P F + Sbjct: 369 FGDIAPLNLPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVW-EKPHRFHPEHFLDAQ 427 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 K + FS G R+C+G+ + +E +LQ+FSF++ Sbjct: 428 GNFVK-HEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSV 471
>CP4G1_DROME (Q9V3S0) Cytochrome P450 4g1 (EC 1.14.-.-) (CYPIVG1)| Length = 556 Score = 67.4 bits (163), Expect = 4e-11 Identities = 44/168 (26%), Positives = 87/168 (51%), Gaps = 9/168 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG---MQSPDPNALNKLKEMTMVLFET 533 GH+ TS ++++ ++ I+ + Q ++ E FG ++ ++K + V+ ET Sbjct: 357 GHDTTSAGSSFALCMMGIHKDIQAKVFAEQKAIFGDNMLRDCTFADTMEMKYLERVILET 416 Query: 532 LRLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWGD----DADEFKP 371 LRLY P + R+ D+ + G +PKG +++ +HR +++ + D D F P Sbjct: 417 LRLYPPVPLIARRLDYDLKLASGPYTVPKGTTVIVLQYCVHRRPDIYPNPTKFDPDNFLP 476 Query: 370 LRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 R N + + + FS GPRSC+G+ ++ML+ K L+ +++ + Sbjct: 477 ERMAN------RHYYSFIPFSAGPRSCVGRKYAMLKLKVLLSTIVRNY 518
>C81D1_ARATH (Q9FG65) Cytochrome P450 81D1 (EC 1.14.-.-)| Length = 502 Score = 67.0 bits (162), Expect = 5e-11 Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 2/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA-LNKLKEMTMVLFETLR 527 G +++ L W++ L +P+ + R E+ G+ A L++L + ++ ETLR Sbjct: 307 GTNTSAVTLEWALSNLLNHPDVISKARDEIDNRVGLDRLIEEADLSELPYLKNIVLETLR 366 Query: 526 LY-SPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L+ + L + D +GS +P+G +++ +HRD W DD D FKP RF+ Sbjct: 367 LHPATPLLVPHMASEDCKIGSYDMPRGTTLLVNAWAIHRDPNTW-DDPDSFKPERFEK-- 423 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 + LLAF +G R+C G + L ++Q F + Sbjct: 424 ---EEEAQKLLAFGLGRRACPGSGLAQRIVGLALGSLIQCFEW 463
>C4AC2_DROME (Q9VMS8) Probable cytochrome P450 4ac2 (EC 1.14.-.-) (CYPIVAC2)| Length = 497 Score = 67.0 bits (162), Expect = 5e-11 Identities = 50/161 (31%), Positives = 86/161 (53%), Gaps = 2/161 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNAL--NKLKEMTMVLFETL 530 G++ TS L +++ +L+++ + Q++ +E+ K S D + N+L M V+ E+L Sbjct: 305 GYDTTSTCLIFTLLMLALHEDVQKKCYEEI-KYLPDDSDDISVFQFNELVYMECVIKESL 363 Query: 529 RLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 RL+ F+ R+ V + V L +PK I I + + RD + + F+P RF Sbjct: 364 RLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARHFSNPK-MFQPDRFFPEN 422 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 T + P + FS G R+CIGQ F++LE K LA +++ F Sbjct: 423 T-VNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNF 462
>CP9H1_DROME (Q9V6H1) Probable cytochrome P450 9h1 (EC 1.14.-.-) (CYPIXH1)| Length = 518 Score = 67.0 bits (162), Expect = 5e-11 Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 9/168 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVL---KEFGMQSPDPNALNKLKEMTMVLFET 533 G E S L + + L + P Q+RL +E++ +E Q + L K+K + MV+ E Sbjct: 320 GFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEA 379 Query: 532 LRLYSPALFMQRKTVADMTVGS------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKP 371 LR + P++ R+ D+ + KG + IPI +H D E + +D + F P Sbjct: 380 LRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENF-EDPEFFNP 438 Query: 370 LRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 RF +G ++V + F +GPR+CIG +++E KS + +L F Sbjct: 439 ERFADGHALESRV---YMPFGVGPRNCIGNRMALMELKSIVYQLLLNF 483
>CP17A_SQUAC (Q92113) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 509 Score = 67.0 bits (162), Expect = 5e-11 Identities = 43/171 (25%), Positives = 83/171 (48%), Gaps = 4/171 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-SPDPNALNKLKEMTMVLFETLR 527 G E +S W + L +PE Q+++++E+ G + +P + + + + E LR Sbjct: 306 GVETSSTAFAWMIIYLIHHPEVQKKIQEEIDSNIGFERTPKMSDKGNMNFLNATIHEILR 365 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KN 356 + + L + +AD ++G +PKG ++I + +H D++ W + D F P RF ++ Sbjct: 366 IQPVSPLLIPHVALADSSIGDYTIPKGTRVIINLWAIHHDEKEW-KNPDAFDPGRFLDED 424 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDY 203 G L F G R C+G+ + +E + +LQ+F+ + P Y Sbjct: 425 G-KYVCSSSESYLPFGAGTRVCLGEMLARMELFLFTSWILQRFTVQVPPGY 474
>CP21A_CANFA (Q8WNW0) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 492 Score = 66.6 bits (161), Expect = 7e-11 Identities = 53/173 (30%), Positives = 88/173 (50%), Gaps = 8/173 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG-------MQSPDPNALNKLKEMTMV 545 G E T+ L+W+V L +PE Q+RL++E+ +E G + DP +L ++ Sbjct: 290 GTETTATTLSWAVAFLLHHPEIQQRLQEELDRELGPGASGSRIPYRDP---TRLPLLSAT 346 Query: 544 LFETLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPL 368 + E LRL L + T ++ +P+G+ ++ + H D+ VW + EF+P Sbjct: 347 VAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGMVVIPNLQGAHLDETVW-ERPQEFRPD 405 Query: 367 RFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 RF + GA+ +LAF G R C+G+ + LE LA +L+ +FTL P Sbjct: 406 RFL--VPGASP---RVLAFGCGARVCLGEPLARLELLVVLAQLLR--AFTLMP 451
>C90B1_ARATH (O64989) Cytochrome P450 90B1 (EC 1.14.-.-) (Steroid| 22-alpha-hydroxylase) (Dwarf4) (Dwarf protein 4) Length = 513 Score = 66.6 bits (161), Expect = 7e-11 Identities = 49/180 (27%), Positives = 82/180 (45%), Gaps = 14/180 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVL------KEFGMQSPDPNALNKLKEMTMVL 542 GHE +S+ + +++ L P+ E LR+E L KE G + + K+ V+ Sbjct: 312 GHETSSVAIALAIFFLQACPKAVEELREEHLEIARAKKELGESELNWDDYKKMDFTQCVI 371 Query: 541 FETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 ETLRL + F+ RK + D+ +P G ++ I +H D + D + F P R+ Sbjct: 372 NETLRLGNVVRFLHRKALKDVRYKGYDIPSGWKVLPVISAVHLDNSRY-DQPNLFNPWRW 430 Query: 361 KNGITGAAKVPHG--------LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 + GA+ G + F GPR C G + LE + ++ KF++ L+ D Sbjct: 431 QQQNNGASSSGSGSFSTWGNNYMPFGGGPRLCAGSELAKLEMAVFIHHLVLKFNWELAED 490
>KO1_ARATH (Q93ZB2) Ent-kaurene oxidase (EC 1.14.13.78) (AtKO1) (Cytochrome| P450 701A3) Length = 509 Score = 66.6 bits (161), Expect = 7e-11 Identities = 50/162 (30%), Positives = 80/162 (49%), Gaps = 2/162 (1%) Frame = -1 Query: 694 NTSLLLT-WSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRLYS 518 +T+L+ T W++Y L+ +P Q+RL KE+ G + L+++ + V ETLR YS Sbjct: 319 DTTLVTTEWAIYELAKHPSVQDRLCKEIQNVCGGEKFKEEQLSQVPYLNGVFHETLRKYS 378 Query: 517 PA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 341 PA L R D +G +P G I I I + DK+ W + +++ P RF + Sbjct: 379 PAPLVPIRYAHEDTQIGGYHVPAGSEIAINIYGCNMDKKRW-ERPEDWWPERFLDDGKYE 437 Query: 340 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 H +AF G R C G + L A + ++Q+F + L Sbjct: 438 TSDLHKTMAFGAGKRVCAGALQASLMAGIAIGRLVQEFEWKL 479
>C94A1_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dependent fatty| acid omega-hydroxylase) Length = 514 Score = 66.6 bits (161), Expect = 7e-11 Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 10/169 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMV---LFET 533 G + TS LTW +LL P +E + E+ K+ + D ++KEM L E+ Sbjct: 316 GKDTTSAALTWFFWLLWKNPRVEEEIVNELSKKSELMVYD-----EVKEMVYTHAALSES 370 Query: 532 LRLYSPALFMQRKTVADMTV-GSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF-- 362 +RLY P ++ V D + + KG + + M R K +WGDD EF+P R+ Sbjct: 371 MRLYPPVPMDSKEAVNDDVLPDGWVVKKGTIVTYHVYAMGRMKSLWGDDWAEFRPERWLE 430 Query: 361 KNGITG----AAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF 227 K+ + G + + F GPR C+G+ + ++ K +A ++ KF Sbjct: 431 KDEVNGKWVFVGRDSYSYPVFQAGPRVCLGKEMAFMQMKRIVAGIVGKF 479
>CP1A1_STECH (Q92116) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 66.2 bits (160), Expect = 9e-11 Identities = 57/187 (30%), Positives = 86/187 (45%), Gaps = 4/187 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + S L+WSV L YPE QERL +E+ + G ++P + KL + + ET R Sbjct: 323 GFDTISTALSWSVMYLVAYPEIQERLYQEMNETVGPDRTPCLSDKPKLPFLEAFILETFR 382 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D ++ +PK + I ++ D E+W D F P RF N Sbjct: 383 HSSFLPFTIPHCTSKDTSLNGYFIPKDTCVFINQWQINHDAELW-KDPSSFNPDRFLNAD 441 Query: 349 TGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 G ++ F MG R CIG+ + E LA+++Q F P P+D Sbjct: 442 GTEVNKLEGEKMMVFGMGKRRCIGEVIARSEVFLFLAILVQNLRFHSMPG---EPLD--- 495 Query: 175 LKPKFGL 155 + P++GL Sbjct: 496 MTPEYGL 502
>CP9B2_DROME (Q9V4I1) Cytochrome P450 9b2 (EC 1.14.-.-) (CYPIXB2)| Length = 505 Score = 66.2 bits (160), Expect = 9e-11 Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 9/172 (5%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP---NALNKLKEMTMVLFETLR 527 EN S L+ + Y L P+ QERL +E+++ + P +A+ K+ M MV+ E+LR Sbjct: 307 ENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLR 366 Query: 526 LYSPALFMQRKTVADMTVGS------LKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLR 365 ++ A R D T+ G I IPI +H D + + +F P R Sbjct: 367 KWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPR-KFDPDR 425 Query: 364 FKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 F G VP+ L F +GPR+CIG +++++ K L +L + SP Sbjct: 426 FSEERKGDM-VPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASP 476
>CP21A_BOVIN (P00191) Cytochrome P450 21 (EC 1.14.99.10) (Cytochrome P450 XXI)| (Steroid 21-hydroxylase) (21-OHase) (P450-C21) (P-450c21) Length = 496 Score = 66.2 bits (160), Expect = 9e-11 Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 6/195 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNK----LKEMTMVLFE 536 G E T+ L+W+V L +PE Q RL++E+ +E G + K L + + E Sbjct: 291 GTETTASTLSWAVAFLLHHPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAE 350 Query: 535 TLRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF- 362 LRL L + +T ++ +P+G+ ++ + H D+ VW + EF+P RF Sbjct: 351 VLRLRPVVPLALPHRTTRPSSIFGYDIPEGMVVIPNLQGAHLDETVW-EQPHEFRPDRFL 409 Query: 361 KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 + G +A LAF G R C+G++ + LE L +LQ +FTL P V A + Sbjct: 410 EPGANPSA------LAFGCGARVCLGESLARLELFVVLLRLLQ--AFTLLPPPVGA-LPS 460 Query: 181 FTLKPKFGLQVFVRP 137 P G+ + V+P Sbjct: 461 LQPDPYCGVNLKVQP 475
>C71A1_PERAE (P24465) Cytochrome P450 71A1 (EC 1.14.-.-) (CYPLXXIA1) (ARP-2)| Length = 471 Score = 66.2 bits (160), Expect = 9e-11 Identities = 45/165 (27%), Positives = 85/165 (51%), Gaps = 2/165 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 G + T++ L W++ L +P+ E+ ++EV + G ++ + L++L + +++ ETLR Sbjct: 305 GTDTTAVTLEWAMAELIKHPDVMEKAQQEVRRVVGKKAKVEEEDLHQLHYLKLIIKETLR 364 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L+ A L + R++ D+ + +P + I + RD + W ++A+EF P RF N Sbjct: 365 LHPVAPLLVPRESTRDVVIRGYHIPAKTRVFINAWAIGRDPKSW-ENAEEFLPERFVNNS 423 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 L+ F G R C G F + + +LA +L F++ L Sbjct: 424 VDFKGQDFQLIPFGAGRRGCPGIAFGISSVEISLANLLYWFNWEL 468
>CP17A_HORSE (Q95328) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 66.2 bits (160), Expect = 9e-11 Identities = 46/170 (27%), Positives = 87/170 (51%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L P+ ++++++E+ + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVKWIVAFLLHDPQLKKKIQEEIDQNVGFSRTPTLSDRNRLLLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K + D ++G + G ++I + +H +++ W D F P RF + Sbjct: 363 IRPVAPMLIPHKALVDSSIGEFAVDDGTNVIINLWALHHNEKEW-HQPDRFMPERFLDP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 TG+ + L L F GPRSCIG+ + E A +LQ+F+ + D Sbjct: 421 TGSQLISPSLSYLPFGAGPRSCIGELLARQELFLFTAWLLQRFNLEVPDD 470
>CP52I_CANMA (Q12586) Cytochrome P450 52A9 (EC 1.14.14.-) (CYPLIIA9)| (Alkane-inducible P450-ALK5-A) Length = 521 Score = 65.9 bits (159), Expect = 1e-10 Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 16/187 (8%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP------NALNKLKEMTMVL 542 G + T+ LL+++++ L+ PE RLR+E+ +FG+ +L + + + V+ Sbjct: 318 GRDTTAGLLSFALFELARNPEVWSRLREEIGDKFGLDEDATIEGISFESLKQCEYLKAVV 377 Query: 541 FETLRLYSPALFMQRKTVADMTV---------GSLKLPKGIAIVIPIPIMHRDKEVWGDD 389 E LR+Y R T+ + + KG + I H D +G D Sbjct: 378 NECLRMYPSVPRNFRIATKHTTLPRGGGPDGKDPIFIKKGAVVSYGINSTHLDPMYYGPD 437 Query: 388 ADEFKPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKF-SFTLS 212 A F P R+ T K+ L F+ GPR C+GQ F++ EA L M+Q F L+ Sbjct: 438 ARLFNPDRWSKPET--KKLGWAFLPFNGGPRICLGQQFALTEASYVLVRMIQNFKELELT 495 Query: 211 PDYVHAP 191 P+ V+ P Sbjct: 496 PNTVYPP 502
>CP1A2_HUMAN (P05177) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450-P3)| (P(3)450) (P450 4) Length = 514 Score = 65.9 bits (159), Expect = 1e-10 Identities = 47/169 (27%), Positives = 80/169 (47%), Gaps = 4/169 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQS-PDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L PE Q +++KE+ G + P + +L + + ET R Sbjct: 317 GFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFR 376 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D T+ +PK + + ++ D E+W +D EF+P RF Sbjct: 377 HSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELW-EDPSEFRPERFLTAD 435 Query: 349 TGAAKVP--HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 A P ++ F MG R CIG+ + E LA++LQ+ F++ P Sbjct: 436 GTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPP 484
>CP11A_DASAM (Q92045) Cytochrome P450 11A1, mitochondrial precursor (EC| 1.14.15.6) (CYPXIA1) (P450(SCC)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) (Fragment) Length = 514 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/164 (26%), Positives = 77/164 (46%), Gaps = 1/164 (0%) Frame = -1 Query: 697 ENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDP-NALNKLKEMTMVLFETLRLY 521 + TS + W +Y L+ +P Q+ +R E+++ DP L + + V+ ETLRLY Sbjct: 330 DTTSTTVHWMMYELAKHPHIQKNVRSEIMEAHQKTEGDPVKMLKSVPLLKCVVKETLRLY 389 Query: 520 SPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGITGA 341 A+ +QR D + + +P G + + + M R+ +++ + +++ P R+ G Sbjct: 390 PVAISIQRYLNEDTVLQNYHIPAGTLVQLGLYAMGRNPKIF-KNPEQYNPERWLKG---- 444 Query: 340 AKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 L F GPR CIG+ + + + MLQ F P Sbjct: 445 EDTHFRHLGFGFGPRQCIGRRIAETQMVLLMIHMLQNFKIETDP 488
>C76A2_SOLME (P37122) Cytochrome P450 76A2 (EC 1.14.-.-) (CYPLXXVIA2) (P-450EG7)| Length = 505 Score = 65.9 bits (159), Expect = 1e-10 Identities = 52/175 (29%), Positives = 80/175 (45%), Gaps = 7/175 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA------LNKLKEMTMVL 542 G E TS + W++ L +PE +++ E+ Q+ +PN + L M VL Sbjct: 310 GTETTSSSVEWALTELLRHPEAMAKVKTEI-----SQAIEPNRKFEDSDIENLPYMQAVL 364 Query: 541 FETLRLYSPALFM-QRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLR 365 E+LRL+ P F+ R+T+ D +PK +++ + RD E W DD FKP R Sbjct: 365 KESLRLHPPLPFLIPRETIQDTKFMGYDVPKDTQVLVNAWAIGRDPECW-DDPMSFKPER 423 Query: 364 FKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYV 200 F +GL+ F G R C+G L +L++F + L PD V Sbjct: 424 FLGSKIDVKGQHYGLIPFGAGRRMCVGLPLGHRMMHFALGSLLREFEWEL-PDGV 477
>C76A1_SOLME (P37121) Cytochrome P450 76A1 (EC 1.14.-.-) (CYPLXXVIA1) (P-450EG8)| (Fragment) Length = 467 Score = 65.9 bits (159), Expect = 1e-10 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 2/165 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA-LNKLKEMTMVLFETLR 527 G E TS + W++ L +P+ +++ E+L+ G ++ L M VL E LR Sbjct: 272 GTETTSSSVEWALTELLRHPQAMAKVKLEILQVIGPNKKFEECDIDSLPYMQAVLKEQLR 331 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L+ P L + RK + D +PKG +++ + RD E W D+ EFKP RF Sbjct: 332 LHPPLPLLIPRKAIQDTKFMGYDIPKGTQVLVNAWAIGRDPEYW-DNPFEFKPERFLESK 390 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 + L+ F G R C+G T +L +F + L Sbjct: 391 VDVKGQNYELIPFGAGRRMCVGLPLGHRMMHFTFGSLLHEFDWEL 435
>C86A1_ARATH (P48422) Cytochrome P450 86A1 (EC 1.14.-.-) (CYPLXXXVI)| (P450-dependent fatty acid omega-hydroxylase) Length = 513 Score = 65.9 bits (159), Expect = 1e-10 Identities = 55/205 (26%), Positives = 98/205 (47%), Gaps = 16/205 (7%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKE---VLKEFGMQSPDP--------NALNKLKE 557 G + +S+ L+W +L+ E + ++ E VLKE + + ++L Sbjct: 304 GRDTSSVALSWFFWLVMNNREVETKIVNELSMVLKETRGNDQEKWTEEPLEFDEADRLVY 363 Query: 556 MTMVLFETLRLYSPALFMQRKTVADMTV--GSLKLPKGIAIVIPIPIMHRDKEVWGDDAD 383 + L ETLRLY P++ K V D V +P+G + I + R K +WG+D Sbjct: 364 LKAALAETLRLY-PSVPQDFKYVVDDDVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCL 422 Query: 382 EFKPLRFKNGITGAAKVP---HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLS 212 EF+P R+ + P + +AF+ GPR+C+G++ + + KS + +L ++ Sbjct: 423 EFRPERWLTADGERFETPKDGYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPV 482 Query: 211 PDYVHAPVDIFTLKPKFGLQVFVRP 137 P + TL K GL+V+++P Sbjct: 483 PGHRVEQKMSLTLFMKNGLRVYLQP 507
>CP1A2_RABIT (P00187) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (P450 isozyme| 4) (P450-PM4) (P450 LM4) Length = 515 Score = 65.9 bits (159), Expect = 1e-10 Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 4/187 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + L+WS+ L P Q ++++E+ G + P + +L + + E R Sbjct: 317 GFDTITTALSWSLMYLVTNPRRQRKIQEELDAVVGRARQPRLSDRPQLPYLEAFILELFR 376 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D T+ +PK I I ++ D ++WGD +EF+P RF Sbjct: 377 HTSFVPFTIPHSTTRDTTLNGFHIPKECCIFINQWQINHDPQLWGDP-EEFRPERFLTAD 435 Query: 349 TGAAKVP--HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 A P + F +G R CIG+ + E LA++LQ+ F++ P PVD Sbjct: 436 GAAINKPLSEKVTLFGLGKRRCIGETLARWEVFLFLAILLQRLEFSVPPG---VPVD--- 489 Query: 175 LKPKFGL 155 L P +GL Sbjct: 490 LTPIYGL 496
>CP1A2_CALJA (O77810) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 65.9 bits (159), Expect = 1e-10 Identities = 53/187 (28%), Positives = 87/187 (46%), Gaps = 4/187 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L PE Q +++KE+ G + P + +L + + ET R Sbjct: 317 GFDTITTAISWSLMYLVTKPEIQRKIQKELDTVIGRGRRPRLSDRPQLPYLEAFILETFR 376 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D T+ +PK + I ++ D ++WGD + EF+P RF Sbjct: 377 HSSFVPFTIPHSTTRDTTLKGFYIPKECCVFINQWQVNHDPQLWGDPS-EFRPERFLTAK 435 Query: 349 TGAAKVP--HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 A P +L F +G R CIG+ E LA++LQ+ F++ P +D Sbjct: 436 GTALNKPLSEKILLFGLGKRRCIGEVLGKWEVFLFLAILLQQLEFSVPPG---VQID--- 489 Query: 175 LKPKFGL 155 L P +GL Sbjct: 490 LTPTYGL 496
>CP6D5_DROME (Q9VFP1) Probable cytochrome P450 6d5 (EC 1.14.-.-) (CYPVID5)| Length = 508 Score = 65.9 bits (159), Expect = 1e-10 Identities = 58/196 (29%), Positives = 92/196 (46%), Gaps = 11/196 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVL----KEFGMQSPDPNALNKLKEMTMVLFE 536 G+E T+ ++++Y L+ PE E+ +++V K G + D A++ +K + + E Sbjct: 315 GYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYD--AISDMKYLEACILE 372 Query: 535 TLRLYSPALFMQRKTVADMTVGSLKL--PKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 T R Y + R D V KL KG I+I + MHRD+E + D +KP R+ Sbjct: 373 TARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPL-AYKPERY 431 Query: 361 -KNG--ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAP 191 +NG T AA +P F GPR CIG + K +A +L F + + Sbjct: 432 LENGKDYTQAAYLP-----FGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIE 486 Query: 190 VDIF--TLKPKFGLQV 149 ++ L PK G+ V Sbjct: 487 FGVYGIPLMPKSGVPV 502
>CP1A1_MOUSE (P00184) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P450-P1)| Length = 524 Score = 65.9 bits (159), Expect = 1e-10 Identities = 45/168 (26%), Positives = 81/168 (48%), Gaps = 3/168 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L P Q ++++E+ G + P + +L + + ET R Sbjct: 322 GFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRDRQPRLSDRPQLPYLEAFILETFR 381 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D ++ +PKG + + ++ D+E+WGD +EF+P RF Sbjct: 382 HSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDP-NEFRPERFLTPS 440 Query: 349 -TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 T ++ + F +G R CIG+ E LA++LQ+ F +SP Sbjct: 441 GTLDKRLSEKVTLFGLGKRKCIGETIGRSEVFLFLAILLQQIEFKVSP 488
>CP1A1_MESAU (Q00557) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) (P-450MC)| Length = 524 Score = 65.9 bits (159), Expect = 1e-10 Identities = 47/168 (27%), Positives = 83/168 (49%), Gaps = 3/168 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L P Q ++++E+ G + P ++L + + ET R Sbjct: 322 GFDTVTTAISWSLMYLVTNPGVQRKIQEELDTVIGRSRRPRLCDRSQLPYLEAFILETFR 381 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D ++ +PKG + + ++ ++E+WGD ++F+P RF Sbjct: 382 HSSFLPFTIPHSTTRDTSLCGFYIPKGHCVFVNQWQINHNQELWGDP-NKFRPERFLTSS 440 Query: 349 TGAAKVPHGLLA-FSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 KV G + F +G R CIG+ LE LA++LQ+ FT+SP Sbjct: 441 GTLDKVLSGKVTLFGLGKRKCIGETIGRLEVFLFLAILLQQIEFTVSP 488
>CP2DA_RAT (P12939) Cytochrome P450 2D10 (EC 1.14.14.1) (CYPIID10) (P450-DB5)| (P450-CMF1B) (Debrisoquine 4-hydroxylase) Length = 504 Score = 65.5 bits (158), Expect = 2e-10 Identities = 47/169 (27%), Positives = 81/169 (47%), Gaps = 6/169 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG-MQSPDPNALNKLKEMTMVLFETLR 527 G T+ LTW++ L+ +YP+ Q R+++E+ + G ++ P+ + V+ E R Sbjct: 309 GMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQR 368 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN-- 356 A L + R T D+ V +PKG ++I + + +D+ VW KPLRF Sbjct: 369 FGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWE------KPLRFHPEH 422 Query: 355 --GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTL 215 G + FS G R+C+G+ + +E +LQ FSF++ Sbjct: 423 FLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQHFSFSV 471
>CP17A_PAPHU (Q9GLD2) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 508 Score = 65.5 bits (158), Expect = 2e-10 Identities = 47/170 (27%), Positives = 84/170 (49%), Gaps = 4/170 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ ++ W V L P+ +++L + + + G ++P + N+L + + E LR Sbjct: 303 GVETTTSVVKWIVAFLLHNPQVKKKLYEGIDQNVGFSRTPTISDRNRLLLLEATIREVLR 362 Query: 526 LYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 + A + + K D ++G + KG ++I + +H +++ W D+F P RF N Sbjct: 363 IRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEW-HQPDQFMPERFLNP- 420 Query: 349 TGAAKVPHGL--LAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPD 206 G + L L F GPRSCIG+ + E +A +LQ+F + D Sbjct: 421 AGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>C77A2_SOLME (P37124) Cytochrome P450 77A2 (EC 1.14.-.-) (CYPLXXVIIA2)| (P-450EG5) Length = 511 Score = 65.5 bits (158), Expect = 2e-10 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 11/200 (5%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTMVLFETLRL 524 G + T+ + W++ L P Q +L +E+ K G D + K+ + V+ E LR Sbjct: 316 GTDTTATAIEWAIGRLIENPNIQSQLYEEIKKTVGENKIDEKDIEKMPYLNAVVKELLRK 375 Query: 523 YSPALFMQRKTVADMT-VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG-- 353 + P V + +G +P G+ + I +P + D +W + ++F P RF G Sbjct: 376 HPPTYMSLTHAVTEPAKLGGYDIPTGVNVEIFLPGISDDPNLWSEP-EKFDPDRFYLGKE 434 Query: 352 ---ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 ITG + V ++ F MG R C G N + + LA ++Q+F + D + VD Sbjct: 435 DADITGVSGVK--MIPFGMGRRICPGLNMATVHVSLMLARLVQEFEWA---DPENTRVDF 489 Query: 181 -----FTLKPKFGLQVFVRP 137 FT+ K L+ ++P Sbjct: 490 TEKLEFTVVMKNTLRAKIKP 509
>C71AI_ARATH (Q9SAB6) Cytochrome P450 71A18 (EC 1.14.-.-)| Length = 497 Score = 65.5 bits (158), Expect = 2e-10 Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 4/169 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEV---LKEFGMQSPDPNALNKLKEMTMVLFET 533 G +S LL W + L PE ++L+ E+ ++ G + N ++ + V+ E Sbjct: 299 GISTSSTLLEWIMTELIRNPECMKKLQNEIRSTIRPHGSYIKEKEVEN-MRYLKAVIKEV 357 Query: 532 LRLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKN 356 R++ P L + R D+ V + G ++I +HRD +WG DA+EFKP R + Sbjct: 358 FRVHPPLPLILPRLLTEDVKVKGYDIAAGTEVLINAWSIHRDPAIWGPDAEEFKPERHLD 417 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 + F G R C G N +M + TLA ++ +F +++ P Sbjct: 418 STLDYHGQDLKYIPFGSGRRICPGINLAMGLVEVTLANLVGRFDWSVDP 466
>C71AE_ARATH (P58045) Cytochrome P450 71A14 (EC 1.14.-.-)| Length = 497 Score = 65.5 bits (158), Expect = 2e-10 Identities = 50/188 (26%), Positives = 85/188 (45%), Gaps = 3/188 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFG--MQSPDPNALNKLKEMTMVLFETL 530 G E T LL W + L +PE ++L+ E+ + + + +K + V+ E L Sbjct: 300 GTETTYALLEWIMTELIRHPECMKKLQDEIRAKATKLILYISEEDVEDMKYLKAVVKEVL 359 Query: 529 RLYSPA-LFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 RL+ P L + R+ D+ + + G ++I + RD WG DA+EF+P R + Sbjct: 360 RLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEEFRPERHLDS 419 Query: 352 ITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFTL 173 + + F G R C G F+M + TLA ++ +F++ + V D + L Sbjct: 420 LVDFRGTNFEFIPFGSGRRICPGIGFAMALVEVTLANLVNRFNWRME---VQHSGDEYDL 476 Query: 172 KPKFGLQV 149 GL V Sbjct: 477 AESTGLDV 484
>CCD1P_DROME (P82712) Probable cytochrome P450 12d1 proximal, mitochondrial| precursor (EC 1.14.-.-) (CYPXIID1) Length = 521 Score = 65.5 bits (158), Expect = 2e-10 Identities = 51/185 (27%), Positives = 89/185 (48%), Gaps = 6/185 (3%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEMTM---VLFET 533 G + T+ LL+ + LS +P+ Q +LR+E+L + N N +K+M V+ ET Sbjct: 326 GVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEEN-MKDMPYLRAVIKET 384 Query: 532 LRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 LR Y L R D+ + ++PKG +++ ++ ++ + DEF P R+ Sbjct: 385 LRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYY-PRPDEFLPERWLRD 443 Query: 352 ITGAAKV---PHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDI 182 K+ P L F GPR CIG+ LE ++T+A +++ F + D + Sbjct: 444 PETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTM 503 Query: 181 FTLKP 167 F ++P Sbjct: 504 FVMEP 508
>C81F1_ARATH (O65790) Cytochrome P450 81F1 (EC 1.14.-.-)| Length = 500 Score = 65.1 bits (157), Expect = 2e-10 Identities = 44/163 (26%), Positives = 80/163 (49%), Gaps = 2/163 (1%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSP-DPNALNKLKEMTMVLFETLR 527 G E +++ L W++ L PE E+ R E+ ++ G D + + L + V+ ET R Sbjct: 301 GTETSAVTLEWAMANLLRNPEVLEKARSEIDEKIGKDRLIDESDIAVLPYLQNVVSETFR 360 Query: 526 LYSPALFM-QRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 L+ A F+ R DM +G +P+ +++ +HRD E+W ++ ++F P R+ +G Sbjct: 361 LFPVAPFLIPRSPTDDMKIGGYDVPRDTIVMVNAWAIHRDPEIW-EEPEKFNPDRYNDG- 418 Query: 349 TGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 G+ + L+ F G R+C G L ++Q F + Sbjct: 419 CGSDYYVYKLMPFGNGRRTCPGAGLGQRIVTLALGSLIQCFEW 461
>CP1A2_MACFA (O77809) Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2)| Length = 515 Score = 65.1 bits (157), Expect = 2e-10 Identities = 46/169 (27%), Positives = 81/169 (47%), Gaps = 4/169 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + + ++WS+ L PE Q +++KE+ G + P + +L + + ET R Sbjct: 317 GFDTIATAISWSLMYLVTKPEIQRKIQKELDAVIGRGRRPRLSDRPQLPYLEAFILETFR 376 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF--KN 356 S F + T D T+ +P+ + I ++ D ++WGD + EF+P RF Sbjct: 377 HSSFVPFTIPHSTTRDTTLNGFYIPRECCVFINQWQVNHDPQLWGDPS-EFRPERFLTAE 435 Query: 355 GITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSP 209 G T + ++ F +G R CIG+ E LA++LQ+ F++ P Sbjct: 436 GTTINKPLSEKIMLFGLGKRRCIGEVLGKWEVFLFLAILLQQLEFSVPP 484
>CP1A1_LIMLI (O42430) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 65.1 bits (157), Expect = 2e-10 Identities = 56/191 (29%), Positives = 86/191 (45%), Gaps = 8/191 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-----SPDPNALNKLKEMTMVLF 539 G + S L+WSV L +PE QERL +E+ + G+ S PN L + + Sbjct: 323 GFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPN----LPFLEAFIL 378 Query: 538 ETLRLYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 E LR S F + T D ++ +PK + I ++ D E+W D F P RF Sbjct: 379 EILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPEMW-KDPSSFNPDRF 437 Query: 361 KNGITGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPV 188 + G ++AF MG R CIG+ + E LA+++QK F + P Sbjct: 438 LSADGSEVNKLDGEKVMAFGMGKRRCIGEVIARNEVYLFLAILIQKLHF------LPIPG 491 Query: 187 DIFTLKPKFGL 155 + + P++GL Sbjct: 492 EKLDMTPEYGL 502
>CP6W1_DROME (Q9V9L1) Probable cytochrome P450 6w1 (EC 1.14.-.-) (CYPVIW1)| Length = 514 Score = 65.1 bits (157), Expect = 2e-10 Identities = 46/172 (26%), Positives = 88/172 (51%), Gaps = 11/172 (6%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNALNKLKEM---TMVLFET 533 G E ++ +T ++Y L+ Q+RLR+E++ FG + D + +++EM + V+ ET Sbjct: 306 GFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDE--DHISYERIQEMPYLSQVVNET 363 Query: 532 LRLYSPALFMQRKTVADMT--------VGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEF 377 LR Y +++R+ +++LP G++I + +HRD + W D +++ Sbjct: 364 LRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYW-PDPEKY 422 Query: 376 KPLRFKNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSF 221 P RF + + + F +GPR+CIG +L++K L +L+ F Sbjct: 423 DPERFNSSNRDNLNMD-AYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRF 473
>CP17A_ICTPU (O73853) Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17)| (P450c17) (Steroid 17-alpha-hydroxylase/17,20 lyase) Length = 514 Score = 65.1 bits (157), Expect = 2e-10 Identities = 45/164 (27%), Positives = 82/164 (50%), Gaps = 4/164 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G E T+ +L WS+ L +P+ Q ++++E+ + G + P N L + + E LR Sbjct: 306 GVETTTTVLKWSILYLIHHPQVQRKIQEELDAKIGRDRHPQVNDRGNLPYLEATIREVLR 365 Query: 526 L--YSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNG 353 + SP L + ++D +G + KG +++ + +H D++ W + + F P RF N Sbjct: 366 IRPVSP-LLIPHVALSDANIGEYTVQKGTRVIVNLWSLHHDEKEW-KNPELFNPERFLNE 423 Query: 352 ITGAAKVPH-GLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFS 224 + P L F G R C+G+ + LE L+ +LQ+F+ Sbjct: 424 EGNSLCCPSLSYLPFGAGVRVCLGEALAKLELFLFLSWILQRFT 467
>CP1A1_PLEPL (Q92100) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 64.7 bits (156), Expect = 3e-10 Identities = 56/191 (29%), Positives = 86/191 (45%), Gaps = 8/191 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-----SPDPNALNKLKEMTMVLF 539 G + S L+WSV L +PE QERL +E+ + G+ S PN L + + Sbjct: 323 GFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPN----LPFLEAFIL 378 Query: 538 ETLRLYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 E LR S F + T D ++ +PK + I ++ D E+W D F P RF Sbjct: 379 EILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPELW-KDPSSFNPDRF 437 Query: 361 KNGITGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPV 188 + G ++AF MG R CIG+ + E LA+++QK F + P Sbjct: 438 LSADGSEVNKLDGEKVMAFGMGKRRCIGEVIARNEVYLFLAIIIQKLHF------LPIPG 491 Query: 187 DIFTLKPKFGL 155 + + P++GL Sbjct: 492 EKLDMTPEYGL 502
>CP1A1_PLAFE (Q9YH64) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 64.7 bits (156), Expect = 3e-10 Identities = 56/191 (29%), Positives = 86/191 (45%), Gaps = 8/191 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQ-----SPDPNALNKLKEMTMVLF 539 G + S L+WSV L +PE QERL +E+ + G+ S PN L + + Sbjct: 323 GFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPN----LPFLEAFIL 378 Query: 538 ETLRLYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 E LR S F + T D ++ +PK + I ++ D E+W D F P RF Sbjct: 379 EILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPELW-KDPSSFNPDRF 437 Query: 361 KNGITGAAKVPHG--LLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPV 188 + G ++AF MG R CIG+ + E LA+++QK F + P Sbjct: 438 LSADGSEVNKLDGEKVMAFGMGKRRCIGEVIARNEVYLFLAIIIQKLHF------LPIPG 491 Query: 187 DIFTLKPKFGL 155 + + P++GL Sbjct: 492 EKLDMTPEYGL 502
>CP1A1_LIZAU (O42231) Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1)| Length = 521 Score = 64.7 bits (156), Expect = 3e-10 Identities = 54/187 (28%), Positives = 88/187 (47%), Gaps = 4/187 (2%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGM-QSPDPNALNKLKEMTMVLFETLR 527 G + S L+WSV L YPE QERL +E+ + G+ ++P + N L + + E R Sbjct: 323 GLDTISTALSWSVMYLVAYPEIQERLYQELKENVGLDRTPVLSDRNNLPLLEAFILEIFR 382 Query: 526 LYSPALF-MQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRFKNGI 350 S F + T D ++ +PK + I ++ D E+W + F P RF + Sbjct: 383 HSSFLPFTIPHCTTKDTSLNGYYIPKDTCVFINQWQINHDPELW-KEPSSFNPDRFLSAD 441 Query: 349 -TGAAKVP-HGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAPVDIFT 176 T KV ++ F +G R CIG+ + E LA+++QK F + P + Sbjct: 442 GTEVNKVDGEKVMVFGLGKRRCIGEVIARNEVYMFLAILIQKLHF------YNLPGEPLD 495 Query: 175 LKPKFGL 155 + P++GL Sbjct: 496 MTPEYGL 502
>CP301_DROME (Q9V6D6) Probable cytochrome P450 301a1, mitochondrial precursor| (EC 1.14.-.-) (CYPCCCIA1) Length = 553 Score = 64.7 bits (156), Expect = 3e-10 Identities = 48/182 (26%), Positives = 88/182 (48%), Gaps = 9/182 (4%) Frame = -1 Query: 703 GHENTSLLLTWSVYLLSIYPEWQERLRKEVLKEFGMQSPDPNA------LNKLKEMTMVL 542 G + S+ + +Y L+ P Q+++ +E+ + PDPN L+++ + + Sbjct: 361 GIDTISMAVCSMLYQLATRPVDQQKVHEELKRLL----PDPNTPLTIPLLDQMHHLKGFI 416 Query: 541 FETLRLYSPALFMQRKTVADMTVGSLKLPKGIAIVIPIPIMHRDKEVWGDDADEFKPLRF 362 E R+YS + R + D + ++PKG+ V P I+ + E + DA F+P R+ Sbjct: 417 KEVFRMYSTVIGNGRTLMEDSVICGYQVPKGVQAVFP-TIVTGNMEEYVTDAATFRPERW 475 Query: 361 ---KNGITGAAKVPHGLLAFSMGPRSCIGQNFSMLEAKSTLALMLQKFSFTLSPDYVHAP 191 ++G T P L + G R C+G+ F+ LE + LA +L+ + +Y H P Sbjct: 476 LKPQHGGTPGKLHPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKL----EYNHKP 531 Query: 190 VD 185 +D Sbjct: 532 LD 533 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 105,589,731 Number of Sequences: 219361 Number of extensions: 2238166 Number of successful extensions: 6243 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5490 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5685 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7026286028 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
