ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal6b20 |
|---|---|
| Clone Library Name | barley_pub |
>SAPKA_ORYSA (Q75H77) Serine/threonine-protein kinase SAPK10 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 10) Length = 362 Score = 258 bits (658), Expect = 2e-68 Identities = 132/165 (80%), Positives = 138/165 (83%), Gaps = 1/165 (0%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRIL VQYSIPDYVHIS ECRDLIA Sbjct: 198 KIADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPECRDLIA 257 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 +IFV NPATRI+IPEIRNHPWFLKNLPADL+DDS MSSQYEEPEQPMQSMDEIMQILAEA Sbjct: 258 RIFVANPATRISIPEIRNHPWFLKNLPADLMDDSKMSSQYEEPEQPMQSMDEIMQILAEA 317 Query: 314 TIPAAGS-RINQFXXXXXXXXXXXXXXXXXXXXDVESSGEIVYAM 183 TIPAAGS INQF DVESSGEIVYAM Sbjct: 318 TIPAAGSGGINQFLNDGLDLDDDMEDLDSDPDLDVESSGEIVYAM 362
>SAPK9_ORYSA (Q75V57) Serine/threonine-protein kinase SAPK9 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 9) Length = 361 Score = 243 bits (620), Expect = 4e-64 Identities = 118/165 (71%), Positives = 137/165 (83%), Gaps = 1/165 (0%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVGAYPFEDP++PKNFRKTIQ+IL VQYSIPDYVHIS ECRDLI Sbjct: 197 KIADVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECRDLIT 256 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 +IFVGNPA+RIT+PEI+NHPWF+KN+PADL+DD +S+QYEEP+QPMQ+M+EIMQILAEA Sbjct: 257 RIFVGNPASRITMPEIKNHPWFMKNIPADLMDDGMVSNQYEEPDQPMQNMNEIMQILAEA 316 Query: 314 TIPAAG-SRINQFXXXXXXXXXXXXXXXXXXXXDVESSGEIVYAM 183 TIPAAG S INQF D+ESSGEIVYAM Sbjct: 317 TIPAAGTSGINQFLTDSLDLDDDMEDMDSDLDLDIESSGEIVYAM 361
>SAPK8_ORYSA (Q7Y0B9) Serine/threonine-protein kinase SAPK8 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 8) Length = 371 Score = 227 bits (578), Expect = 3e-59 Identities = 113/161 (70%), Positives = 129/161 (80%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGVTLYVM+VGAYPFEDP+EPKNFRKTIQRIL+VQYSIP+ V IS ECR LI++IF Sbjct: 211 DVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTIQRILNVQYSIPENVDISPECRHLISRIF 270 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 VG+P+ RITIPEIR+H WFLKNLPADL+DD +MSSQYEEP+QPMQ+MD+IMQIL EATIP Sbjct: 271 VGDPSLRITIPEIRSHGWFLKNLPADLMDDDSMSSQYEEPDQPMQTMDQIMQILTEATIP 330 Query: 305 AAGSRINQFXXXXXXXXXXXXXXXXXXXXDVESSGEIVYAM 183 A SRIN DV+SSGEIVYAM Sbjct: 331 PACSRINHILTDGLDLDDDMDDLDSDSDIDVDSSGEIVYAM 371
>SAPK2_ORYSA (Q84TC6) Serine/threonine-protein kinase SAPK2 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 2) Length = 339 Score = 182 bits (463), Expect = 6e-46 Identities = 91/164 (55%), Positives = 111/164 (67%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVGAYPFEDPDEP+NFRKTI RILSVQY +PDYV +S ECR L++ Sbjct: 179 KVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLS 238 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 +IFV NP RITIPEI+NHPWFLKNLP ++ D+ MS Q + P Q ++EIM I+ EA Sbjct: 239 RIFVANPEQRITIPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTPSQGLEEIMAIIQEA 298 Query: 314 TIPAAGSRINQFXXXXXXXXXXXXXXXXXXXXDVESSGEIVYAM 183 P GS+ F DVE SG+ V A+ Sbjct: 299 RKPGDGSK---FSGQIPGLGSMELDDVDTDDIDVEDSGDFVCAL 339
>SAPK1_ORYSA (Q75LR7) Serine/threonine-protein kinase SAPK1 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 1) Length = 342 Score = 182 bits (461), Expect = 1e-45 Identities = 87/164 (53%), Positives = 113/164 (68%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVGAYPFEDPD+P+NFRKTI RILSVQYSIPDYV +S++CR L++ Sbjct: 179 KVADVWSCGVTLYVMLVGAYPFEDPDDPRNFRKTITRILSVQYSIPDYVRVSADCRHLLS 238 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 +IFVGNP RITIPEI+NHPWFLKNLP ++ D+ S Q + P QS++E+M I+ EA Sbjct: 239 RIFVGNPEQRITIPEIKNHPWFLKNLPIEMTDEYQRSMQLADMNTPSQSLEEVMAIIQEA 298 Query: 314 TIPAAGSRINQFXXXXXXXXXXXXXXXXXXXXDVESSGEIVYAM 183 P ++ D+E+SG+ V A+ Sbjct: 299 RKPGDAMKLAGAGQVACLGSMDLDDIDDIDDIDIENSGDFVCAL 342
>AAIP_WHEAT (Q02066) Abscisic acid-inducible protein kinase (EC 2.7.11.1)| (Fragment) Length = 332 Score = 174 bits (440), Expect = 3e-43 Identities = 79/123 (64%), Positives = 97/123 (78%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVGAYPFEDPDEP+NFRKTI RILSVQYS+PDYV +S +C L++ Sbjct: 169 KVADVWSCGVTLYVMLVGAYPFEDPDEPRNFRKTITRILSVQYSVPDYVRVSMDCIHLLS 228 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 +IFVGNP RITIPEI+NHPWFLK LP ++ D+ S Q + P QS++E M I+ EA Sbjct: 229 RIFVGNPQQRITIPEIKNHPWFLKRLPVEMTDEYQRSMQLADMNTPSQSLEEAMAIIQEA 288 Query: 314 TIP 306 P Sbjct: 289 QKP 291
>SAPK7_ORYSA (Q7XQP4) Serine/threonine-protein kinase SAPK7 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 7) Length = 359 Score = 169 bits (428), Expect = 7e-42 Identities = 80/128 (62%), Positives = 101/128 (78%), Gaps = 4/128 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGVTLYVMLVGAYPFEDPD+PKNFRKTI RI+S+QY IP+YVH+S +CR L+++IF Sbjct: 182 DVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIF 241 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEE----PEQPMQSMDEIMQILAE 318 V NPA RITI EIRNHPWFLKNLP +L ++ + Y++ P +QS++EIM+I+ E Sbjct: 242 VANPAKRITIREIRNHPWFLKNLPRELT-EAAQAMYYKKDNSAPTYSVQSVEEIMKIVEE 300 Query: 317 ATIPAAGS 294 A P S Sbjct: 301 ARTPPRSS 308
>SAPK6_ORYSA (Q6ZI44) Serine/threonine-protein kinase SAPK6 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 6) Length = 365 Score = 167 bits (423), Expect = 3e-41 Identities = 79/131 (60%), Positives = 101/131 (77%), Gaps = 4/131 (3%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVGAYPFEDPD+PKNFRKTI RI+S+QY IP+YVHIS +CR L++ Sbjct: 179 KMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHISQDCRQLLS 238 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPM----QSMDEIMQI 327 +IFV NPA RITI EIRNHPWF+KNLP +L ++ + Y++ Q++DEIM+I Sbjct: 239 RIFVANPAKRITIREIRNHPWFMKNLPRELT-EAAQAKYYKKDNSARTFSDQTVDEIMKI 297 Query: 326 LAEATIPAAGS 294 + EA P S Sbjct: 298 VQEAKTPPPSS 308
>ASK2_ARATH (P43292) Serine/threonine-protein kinase ASK2 (EC 2.7.11.1)| Length = 353 Score = 166 bits (421), Expect = 5e-41 Identities = 75/121 (61%), Positives = 99/121 (81%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGVTLYVMLVGAYPFEDP++PKNFRKTIQRI++VQY IPDYVHIS EC+ L+++IF Sbjct: 182 DVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHLLSRIF 241 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 V N A RIT+ EI+NHPW+LKNLP +L++ + + + +QS+++IM+I+ EA P Sbjct: 242 VTNSAKRITLKEIKNHPWYLKNLPKELLESAQAAYYKRDTSFSLQSVEDIMKIVGEARNP 301 Query: 305 A 303 A Sbjct: 302 A 302
>SAPK4_ORYSA (Q5N942) Serine/threonine-protein kinase SAPK4 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 4) Length = 360 Score = 162 bits (409), Expect = 1e-39 Identities = 79/131 (60%), Positives = 97/131 (74%), Gaps = 3/131 (2%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 +L +VWSCGVTLYVMLVGAYPFED D+PKN RKTIQRI+SVQY IPDYVHIS+EC+ LIA Sbjct: 179 KLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAECKQLIA 238 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPM---QSMDEIMQIL 324 +IFV NP RIT+ EI++HPWFLKNLP +L + + + P Q+ +EIM+I+ Sbjct: 239 RIFVNNPLRRITMKEIKSHPWFLKNLPRELTETAQAMYYRRDNSVPSFSDQTSEEIMKIV 298 Query: 323 AEATIPAAGSR 291 EA SR Sbjct: 299 QEARTMPKSSR 309
>SAPK3_ORYSA (Q75V63) Serine/threonine-protein kinase SAPK3 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 3) (Protein kinase REK) Length = 334 Score = 161 bits (408), Expect = 1e-39 Identities = 72/123 (58%), Positives = 97/123 (78%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVG+YPFEDP +P+NFRKTI RIL VQYSIPDYV +SS+CR L++ Sbjct: 180 KVADVWSCGVTLYVMLVGSYPFEDPGDPRNFRKTISRILGVQYSIPDYVRVSSDCRRLLS 239 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 +IFV +P+ RITIPEI+ H WFLKNLP ++ + + + P Q+++EIM+I+ EA Sbjct: 240 QIFVADPSKRITIPEIKKHTWFLKNLPKEISEREKADYKDTDAAPPTQAVEEIMRIIQEA 299 Query: 314 TIP 306 +P Sbjct: 300 KVP 302
>ASK1_ARATH (P43291) Serine/threonine-protein kinase ASK1 (EC 2.7.11.1)| Length = 363 Score = 160 bits (404), Expect = 4e-39 Identities = 76/131 (58%), Positives = 102/131 (77%), Gaps = 3/131 (2%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ +VWSCGVTLYVMLVGAYPFED ++PKNFRKTIQ+I++VQY IPDYVHIS +C++L++ Sbjct: 179 KMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCKNLLS 238 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP---MQSMDEIMQIL 324 +IFV N RITI EI+ H WFLKNLP +L + T + Y + E P +Q+++EIM+I+ Sbjct: 239 RIFVANSLKRITIAEIKKHSWFLKNLPRELTE--TAQAAYFKKENPTFSLQTVEEIMKIV 296 Query: 323 AEATIPAAGSR 291 A+A P SR Sbjct: 297 ADAKTPPPVSR 307
>SAPK5_ORYSA (Q7XKA8) Serine/threonine-protein kinase SAPK5 (EC 2.7.11.1)| (Osmotic stress/abscisic acid-activated protein kinase 5) Length = 370 Score = 152 bits (383), Expect = 1e-36 Identities = 76/139 (54%), Positives = 99/139 (71%), Gaps = 16/139 (11%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 +L +VWSCGVTLYVMLVGAYPFEDP +PKNFRKTI RI+SVQY IP+YVH+S CR L++ Sbjct: 179 KLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYVHVSQPCRHLLS 238 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDD---------------STMSSQYEEPEQ 360 +IFV NP RI++ EI++HPWFLKNLP +L ++ S+ SS Sbjct: 239 RIFVANPYKRISMGEIKSHPWFLKNLPRELKEEAQAVYYNRRGADHAASSASSAAAAAAF 298 Query: 359 PMQSMDEIMQILAEA-TIP 306 QS+++IM+I+ EA T+P Sbjct: 299 SPQSVEDIMRIVQEAQTVP 317
>KIN11_ARATH (P92958) SNF1-related protein kinase catalytic alpha subunit KIN11| (EC 2.7.11.1) (AKIN11) (AKIN alpha1) Length = 512 Score = 83.2 bits (204), Expect = 7e-16 Identities = 48/112 (42%), Positives = 65/112 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV LY +L G PF+D + P F+K I Y++P H+SSE RDLI ++ Sbjct: 200 DVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGI----YTLPS--HLSSEARDLIPRML 253 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQ 330 + +P RITIPEIR H WF +LP L S + EQ + +EI+Q Sbjct: 254 IVDPVKRITIPEIRQHRWFQTHLPRYLA-----VSPPDTVEQAKKINEEIVQ 300
>KIN10_ARATH (Q38997) SNF1-related protein kinase catalytic alpha subunit KIN10| (EC 2.7.11.1) (AKIN10) (AKIN alpha2) Length = 535 Score = 80.5 bits (197), Expect = 4e-15 Identities = 40/84 (47%), Positives = 53/84 (63%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV LY +L G PF+D + P F+K I Y++P H+S RDLI ++ Sbjct: 222 DVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGI----YTLPS--HLSPGARDLIPRML 275 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 V +P R+TIPEIR HPWF +LP Sbjct: 276 VVDPMKRVTIPEIRQHPWFQAHLP 299
>SNF1_SCHPO (O74536) SNF1-like protein kinase ssp2 (EC 2.7.11.1)| Length = 576 Score = 76.3 bits (186), Expect = 8e-14 Identities = 40/84 (47%), Positives = 52/84 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCG+ LYVMLVG PF+D P F+K + S Y +PD+ +S + LI ++ Sbjct: 213 DVWSCGIVLYVMLVGRLPFDDEFIPNLFKK----VNSCVYVMPDF--LSPGAQSLIRRMI 266 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 V +P RITI EIR PWF NLP Sbjct: 267 VADPMQRITIQEIRRDPWFNVNLP 290
>RKIN1_SECCE (Q02723) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 502 Score = 74.3 bits (181), Expect = 3e-13 Identities = 38/84 (45%), Positives = 52/84 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV LY +L GA PF+D + P F+K I Y +P +++S RDLI+++ Sbjct: 197 DVWSCGVILYALLCGAVPFDDDNIPNLFKK----IKGGTYILP--IYLSDLVRDLISRML 250 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 + +P RITI EIR H WF LP Sbjct: 251 IVDPMKRITIGEIRKHSWFQNRLP 274
>TRIB1_HUMAN (Q96RU8) Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled| receptor induced protein 2) (GIG-2) Length = 372 Score = 70.9 bits (172), Expect = 3e-12 Identities = 42/101 (41%), Positives = 52/101 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY +LVG YPF D D F K I Q+ IP+ HIS + R LI + Sbjct: 266 DVWSLGVMLYTLLVGRYPFHDSDPSALFSK----IRRGQFCIPE--HISPKARCLIRSLL 319 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPE 363 P+ R+T PEI HPWF L +D +S PE Sbjct: 320 RREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPE 360
>TRIB1_MOUSE (Q8K4K4) Tribbles homolog 1 (TRB-1)| Length = 372 Score = 68.9 bits (167), Expect = 1e-11 Identities = 41/101 (40%), Positives = 52/101 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY +LVG YPF D D F K I Q+ IP+ H+S + R LI + Sbjct: 266 DVWSLGVMLYTLLVGRYPFHDSDPSALFSK----IRRGQFCIPE--HVSPKARCLIRSLL 319 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPE 363 P+ R+T P+I HPWF L VD +S PE Sbjct: 320 RREPSERLTAPQILLHPWFEYVLEPGYVDSEIGTSDQIVPE 360
>KKK1_YEAST (P34244) Probable serine/threonine-protein kinase YKL101W (EC| 2.7.11.1) Length = 1518 Score = 67.8 bits (164), Expect = 3e-11 Identities = 38/90 (42%), Positives = 54/90 (60%), Gaps = 2/90 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCG+ L+ +L G PF D N +K + ++ S +Y +P ++SSE RDLI+KI Sbjct: 297 DVWSCGIVLFALLTGHLPFNDD----NIKKLLLKVQSGKYQMPS--NLSSEARDLISKIL 350 Query: 485 VGNPATRITIPEIRNHPWFLK--NLPADLV 402 V +P RIT EI HP K +LP + V Sbjct: 351 VIDPEKRITTQEILKHPLIKKYDDLPVNKV 380
>IPL1_DEBHA (Q6BVA0) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 412 Score = 66.6 bits (161), Expect = 6e-11 Identities = 33/82 (40%), Positives = 47/82 (57%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS G+ Y LVG PFE+ D+ T +RI V IP + +SSE DLI ++ Sbjct: 329 DIWSLGILCYEFLVGKPPFEEIDK----NSTYKRIAKVDLKIPSF--LSSEATDLILRLL 382 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 +P RIT+ E+ NHPW + N Sbjct: 383 QKSPKKRITLAEVMNHPWIMNN 404
>CIPK1_ORYSA (Q6X4A2) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1)| Length = 449 Score = 66.6 bits (161), Expect = 6e-11 Identities = 36/95 (37%), Positives = 51/95 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LYV+L G PFED N ++I Q++ P + S+ + LI +I Sbjct: 203 DIWSCGVILYVLLAGFLPFED----DNIIALYKKISEAQFTCPSW--FSTGAKKLITRIL 256 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSS 381 NP TRITI +I PWF K + D+ +S Sbjct: 257 DPNPTTRITISQILEDPWFKKGYKPPVFDEKYETS 291
>SN1L1_RAT (Q9R1U5) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (Salt-inducible protein kinase) (Protein kinase KID2) Length = 776 Score = 65.5 bits (158), Expect = 1e-10 Identities = 36/96 (37%), Positives = 54/96 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LYV++ G+ PF+ P+ P QR+L ++ IP ++ S +C LI ++ Sbjct: 206 DIWSLGVVLYVLVCGSLPFDGPNLPT----LRQRVLEGRFRIPFFM--SQDCETLIRRML 259 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQ 378 V +PA RITI +IR H W + DD S Q Sbjct: 260 VVDPAKRITIAQIRQHRWMQADPTLLQQDDPAFSMQ 295
>SNF1_CANTR (O94168) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 619 Score = 65.5 bits (158), Expect = 1e-10 Identities = 47/133 (35%), Positives = 67/133 (50%), Gaps = 11/133 (8%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYVML G PF+D P F+K I + Y++P+Y +S + L+ ++ Sbjct: 231 DVWSSGVILYVMLCGRLPFDDEFIPALFKK----ISNGVYTLPNY--LSPGAKHLLTRML 284 Query: 485 VGNPATRITIPEIRNHPWFLKN-----LPADLVDDSTMSSQYEEPEQPMQSM------DE 339 V NP RITI EI WF ++ LP DL T +E S+ DE Sbjct: 285 VVNPLNRITIHEIMEDEWFKQDMPDYLLPPDLSKIKTSKIDIDEDVISALSVTMGYDRDE 344 Query: 338 IMQILAEATIPAA 300 I+ ++ +A AA Sbjct: 345 IISVIEKANREAA 357
>SNF1_CANAL (P52497) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 620 Score = 65.1 bits (157), Expect = 2e-10 Identities = 35/84 (41%), Positives = 51/84 (60%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYVML G PF+D P F+K I + Y++P+Y +S+ + L+ ++ Sbjct: 233 DVWSAGVILYVMLCGRLPFDDEFIPALFKK----ISNGVYTLPNY--LSAGAKHLLTRML 286 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 V NP RITI EI WF +++P Sbjct: 287 VVNPLNRITIHEIMEDDWFKQDMP 310
>SN1L2_HUMAN (Q9H0K1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 926 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/109 (33%), Positives = 60/109 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LYV++ GA PF+ P P QR+L ++ IP ++ S +C LI ++ Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPI----LRQRVLEGRFRIPYFM--SEDCEHLIRRML 252 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDE 339 V +P+ R+TI +I+ H W L +P V + Q +E E + +E Sbjct: 253 VLDPSKRLTIAQIKEHKWMLIEVP---VQRPVLYPQEQENEPSIGEFNE 298
>SN1L2_PONPY (Q5REX1) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) Length = 925 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/109 (33%), Positives = 60/109 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LYV++ GA PF+ P P QR+L ++ IP ++ S +C LI ++ Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPI----LRQRVLEGRFRIPYFM--SEDCEHLIRRML 252 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDE 339 V +P+ R+TI +I+ H W L +P V + Q +E E + +E Sbjct: 253 VLDPSKRLTIAQIKEHKWMLIEVP---VQRPVLYPQEQENEPSIGEFNE 298
>SNRK_HUMAN (Q9NRH2) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 765 Score = 64.7 bits (156), Expect = 2e-10 Identities = 27/78 (34%), Positives = 50/78 (64%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV L++++ G PF++ ++ + T+ I+ +Y++P H+S EC+DLI ++ Sbjct: 197 DIWSLGVILFMLVCGQPPFQEANDSE----TLTMIMDCKYTVPS--HVSKECKDLITRML 250 Query: 485 VGNPATRITIPEIRNHPW 432 +P R ++ EI NHPW Sbjct: 251 QRDPKRRASLEEIENHPW 268
>SN1L1_MOUSE (Q60670) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1-like kinase) Length = 779 Score = 64.3 bits (155), Expect = 3e-10 Identities = 33/78 (42%), Positives = 49/78 (62%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYV++ G+ PF+ P+ P QR+L ++ IP ++ S +C LI ++ Sbjct: 206 DVWSLGVVLYVLVCGSLPFDGPNLPT----LRQRVLEGRFRIPFFM--SQDCETLIRRML 259 Query: 485 VGNPATRITIPEIRNHPW 432 V +PA RITI +IR H W Sbjct: 260 VVDPAKRITIAQIRQHRW 277
>SN1L1_HUMAN (P57059) Serine/threonine-protein kinase SNF1-like kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) Length = 783 Score = 64.3 bits (155), Expect = 3e-10 Identities = 32/78 (41%), Positives = 49/78 (62%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LYV++ G+ PF+ P+ P QR+L ++ IP ++ S +C LI ++ Sbjct: 206 DIWSLGVVLYVLVCGSLPFDGPNLPT----LRQRVLEGRFRIPFFM--SQDCESLIRRML 259 Query: 485 VGNPATRITIPEIRNHPW 432 V +PA RITI +IR H W Sbjct: 260 VVDPARRITIAQIRQHRW 277
>KCC4_YEAST (P25389) Probable serine/threonine-protein kinase KCC4 (EC| 2.7.11.1) Length = 1037 Score = 63.5 bits (153), Expect = 5e-10 Identities = 32/81 (39%), Positives = 48/81 (59%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV L+ +L G PF++ E N R + ++ Q+ +P+ IS + +DLI KI Sbjct: 209 DVWSCGVILFALLTGRLPFDE--ENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKIL 266 Query: 485 VGNPATRITIPEIRNHPWFLK 423 V +P RI I +I +HP K Sbjct: 267 VVDPRQRIKIRDILSHPLLKK 287
>CDPK_SOYBN (P28583) Calcium-dependent protein kinase SK5 (EC 2.7.11.1) (CDPK)| Length = 508 Score = 63.2 bits (152), Expect = 7e-10 Identities = 37/117 (31%), Positives = 61/117 (52%), Gaps = 1/117 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY++L G PF EP FR+ + + + + + IS +DLI K+ Sbjct: 216 DVWSAGVILYILLSGVPPFWAESEPGIFRQIL--LGKLDFHSEPWPSISDSAKDLIRKML 273 Query: 485 VGNPATRITIPEIRNHPWFL-KNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAE 318 NP TR+T E+ HPW + N+ D DS + S+ ++ + ++++AE Sbjct: 274 DQNPKTRLTAHEVLRHPWIVDDNIAPDKPLDSAVLSRLKQFSAMNKLKKMALRVIAE 330
>STK6_XENLA (Q91820) Serine/threonine-protein kinase Eg2 (EC 2.7.11.1) (pEg2)| (p46Eg265) Length = 407 Score = 63.2 bits (152), Expect = 7e-10 Identities = 34/96 (35%), Positives = 49/96 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV Y LVG PFE + +R RI V++ P YV S E RDL++K+ Sbjct: 318 DLWSLGVLCYEFLVGKPPFETDTHQETYR----RISKVEFQYPPYV--SEEARDLVSKLL 371 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQ 378 NP R+ + + HPW +KN D+ +Q Sbjct: 372 KHNPNHRLPLKGVLEHPWIIKNSQLKKKDEPLPGAQ 407
>IPL1_ASHGO (Q755C4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 367 Score = 63.2 bits (152), Expect = 7e-10 Identities = 32/84 (38%), Positives = 48/84 (57%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GV Y +LVG+ PFE+ + T +RIL PD H+ +E R LI+++ Sbjct: 288 DVWALGVLTYELLVGSPPFEEESK----ELTYKRILKRNLIFPD--HVDTEARHLISRLL 341 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 +P RI + E++ HPW KN P Sbjct: 342 EYDPGDRIPLKEVKKHPWIEKNKP 365
>KCC2A_MOUSE (P11798) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 63.2 bits (152), Expect = 7e-10 Identities = 29/78 (37%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ + +++ R + + P++ ++ E +DLI K+ Sbjct: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQIKAR--AYDFPSPEWDTVTPEAKDLINKML 252 Query: 485 VGNPATRITIPEIRNHPW 432 NP+ RIT E HPW Sbjct: 253 TINPSKRITAAEALKHPW 270
>SN1L2_MOUSE (Q8CFH6) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Salt-inducible kinase 2) Length = 931 Score = 62.8 bits (151), Expect = 9e-10 Identities = 36/109 (33%), Positives = 60/109 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LYV++ GA PF+ P P QR+L ++ IP + +S +C LI ++ Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLP----ILRQRVLEGRFRIPYF--MSEDCEHLIRRML 252 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDE 339 V +P+ R++I +I+ H W L +P V + Q +E E + +E Sbjct: 253 VLDPSKRLSIAQIKEHKWMLIEVP---VQRPILYPQEQENEPSIGEFNE 298
>KIN1_SCHPO (P22987) Protein kinase kin1 (EC 2.7.11.1)| Length = 891 Score = 62.8 bits (151), Expect = 9e-10 Identities = 29/82 (35%), Positives = 48/82 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G+ LYV++ G PF+D +N +I P Y +SS+C+ L++++ Sbjct: 323 DVWSFGIVLYVLVCGKVPFDD----QNMSALHAKIKKGTVEYPSY--LSSDCKGLLSRML 376 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 V +P R T+ E+ NHPW ++N Sbjct: 377 VTDPLKRATLEEVLNHPWMIRN 398
>KCC2D_RAT (P15791) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 533 Score = 62.8 bits (151), Expect = 9e-10 Identities = 29/78 (37%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ + +++ + + + P++ ++ E +DLI K+ Sbjct: 196 DMWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYDFPSPEWDTVTPEAKDLINKML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT E HPW Sbjct: 254 TINPAKRITASEALKHPW 271
>KCC2D_HUMAN (Q13557) Calcium/calmodulin-dependent protein kinase type II delta| chain (EC 2.7.11.17) (CaM-kinase II delta chain) (CaM kinase II delta subunit) (CaMK-II delta subunit) Length = 499 Score = 62.8 bits (151), Expect = 9e-10 Identities = 29/78 (37%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ + +++ + + + P++ ++ E +DLI K+ Sbjct: 196 DMWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYDFPSPEWDTVTPEAKDLINKML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT E HPW Sbjct: 254 TINPAKRITASEALKHPW 271
>CPK24_ARATH (Q9LDI3) CBL-interacting serine/threonine-protein kinase 24 (EC| 2.7.11.1) (SNF1-related kinase 3.11) (SALT OVERLY SENSITIVE 2 protein) Length = 446 Score = 62.4 bits (150), Expect = 1e-09 Identities = 34/82 (41%), Positives = 48/82 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV L+V+L G PF + D P +RK I + ++S P + S+E + LI +I Sbjct: 192 DIWSCGVILFVILAGYLPFSETDLPGLYRK----INAAEFSCPPW--FSAEVKFLIHRIL 245 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 NP TRI I I+ PWF N Sbjct: 246 DPNPKTRIQIQGIKKDPWFRLN 267
>SNF1_CANGA (Q00372) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 612 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/111 (35%), Positives = 58/111 (52%), Gaps = 1/111 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV LYVML PF+D P F+ I + Y++P + +S DLI ++ Sbjct: 218 DVWSCGVILYVMLCRRLPFDDESIPVLFK----NISNGVYTLPKF--LSPGASDLIKRML 271 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLV-DDSTMSSQYEEPEQPMQSMDEI 336 + NP RI+I EI WF +L LV D Q+ + ++++EI Sbjct: 272 IVNPLNRISIHEIMQDEWFKVDLAEYLVPQDLKQQEQFNKKSGNEENVEEI 322
>KKCC1_HUMAN (Q8N5S9) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 62.4 bits (150), Expect = 1e-09 Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 1/107 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQR-ILSVQYSIPDYVHISSECRDLIAKI 489 +VW+ GVTLY + G PF D +F + R I + P+ IS E +DLI K+ Sbjct: 335 DVWATGVTLYCFVYGKCPFID-----DFILALHRKIKNEPVVFPEEPEISEELKDLILKM 389 Query: 488 FVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQS 348 NP TRI +P+I+ HPW KN L + S E E+ +++ Sbjct: 390 LDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 436
>PLO1_SCHPO (P50528) Serine/threonine-protein kinase plo1 (EC 2.7.11.21)| Length = 683 Score = 62.4 bits (150), Expect = 1e-09 Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV +Y +L+G PF+D + +RK I + YS P V IS+E +DLI+ + Sbjct: 222 DLWSAGVVMYALLIGKPPFQDKEVKTIYRK----IKANSYSFPSNVDISAEAKDLISSLL 277 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEP-EQPMQSMDEIMQILAEAT 312 +P+ R +I +I +H +F A + D + S P Q S + +A A+ Sbjct: 278 THDPSIRPSIDDIVDHEFFHTGYMASTLPDEILHSMPIWPSSQSKSSFQRNLDFVASAS 336
>SN1L2_CHICK (Q9IA88) Serine/threonine-protein kinase SNF1-like kinase 2 (EC| 2.7.11.1) (Qin-induced kinase) Length = 798 Score = 61.6 bits (148), Expect = 2e-09 Identities = 30/78 (38%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LYV++ G+ PF+ P+ P QR+L ++ IP + +S +C LI ++ Sbjct: 205 DIWSLGVVLYVLVCGSLPFDGPNLP----TLRQRVLEGRFRIPYF--MSEDCETLIRRML 258 Query: 485 VGNPATRITIPEIRNHPW 432 V +P RITI +I+ H W Sbjct: 259 VVDPTKRITISQIKQHKW 276
>AAPK2_RAT (Q09137) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 11/112 (9%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY +L G PF+D P F+K I + IP+Y++ S L+ + Sbjct: 196 DIWSCGVILYALLCGTLPFDDEHVPTLFKK----IRGGVFYIPEYLNRS--IATLLMHML 249 Query: 485 VGNPATRITIPEIRNHPWFLKNLP-----------ADLVDDSTMSSQYEEPE 363 +P R TI +IR H WF ++LP A+++DD + E+ E Sbjct: 250 QVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFE 301
>AAPK2_PONPY (Q5RD00) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 11/112 (9%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY +L G PF+D P F+K I + IP+Y++ S L+ + Sbjct: 196 DIWSCGVILYALLCGTLPFDDEHVPTLFKK----IRGGVFYIPEYLNRS--VATLLMHML 249 Query: 485 VGNPATRITIPEIRNHPWFLKNLP-----------ADLVDDSTMSSQYEEPE 363 +P R TI +IR H WF ++LP A+++DD + E+ E Sbjct: 250 QVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFE 301
>AAPK2_PIG (Q28948) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 11/112 (9%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY +L G PF+D P F+K I + IP+Y++ S L+ + Sbjct: 196 DIWSCGVILYALLCGTLPFDDEHVPTLFKK----IRGGVFYIPEYLNRS--VATLLMHML 249 Query: 485 VGNPATRITIPEIRNHPWFLKNLP-----------ADLVDDSTMSSQYEEPE 363 +P R TI +IR H WF ++LP A+++DD + E+ E Sbjct: 250 QVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFE 301
>AAPK2_HUMAN (P54646) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMPK alpha-2 chain) Length = 552 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 11/112 (9%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY +L G PF+D P F+K I + IP+Y++ S L+ + Sbjct: 196 DIWSCGVILYALLCGTLPFDDEHVPTLFKK----IRGGVFYIPEYLNRS--VATLLMHML 249 Query: 485 VGNPATRITIPEIRNHPWFLKNLP-----------ADLVDDSTMSSQYEEPE 363 +P R TI +IR H WF ++LP A+++DD + E+ E Sbjct: 250 QVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKFE 301
>KCC2A_RAT (P11275) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 61.6 bits (148), Expect = 2e-09 Identities = 28/78 (35%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ + +++ + + + P++ ++ E +DLI K+ Sbjct: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYDFPSPEWDTVTPEAKDLINKML 252 Query: 485 VGNPATRITIPEIRNHPW 432 NP+ RIT E HPW Sbjct: 253 TINPSKRITAAEALKHPW 270
>KCC2A_PONPY (Q5RCC4) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 61.6 bits (148), Expect = 2e-09 Identities = 28/78 (35%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ + +++ + + + P++ ++ E +DLI K+ Sbjct: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYDFPSPEWDTVTPEAKDLINKML 252 Query: 485 VGNPATRITIPEIRNHPW 432 NP+ RIT E HPW Sbjct: 253 TINPSKRITAAEALKHPW 270
>KCC2A_HUMAN (Q9UQM7) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) (CaM kinase II alpha subunit) (CaMK-II alpha subunit) Length = 478 Score = 61.6 bits (148), Expect = 2e-09 Identities = 28/78 (35%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ + +++ + + + P++ ++ E +DLI K+ Sbjct: 195 DLWACGVILYILLVGYPPFWDEDQHRLYQQI--KAGAYDFPSPEWDTVTPEAKDLINKML 252 Query: 485 VGNPATRITIPEIRNHPW 432 NP+ RIT E HPW Sbjct: 253 TINPSKRITAAEALKHPW 270
>CPK11_ARATH (O22932) CBL-interacting serine/threonine-protein kinase 11 (EC| 2.7.11.1) (SOS2-like protein kinase PKS5) (SOS-interacting protein 4) (SNF1-related kinase 3.22) Length = 435 Score = 61.2 bits (147), Expect = 3e-09 Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 6/104 (5%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCG+ L+V++ G PF DP N ++I +Y P + +S + + ++++ Sbjct: 205 DVWSCGIVLFVLVAGYLPFNDP----NVMNMYKKIYKGEYRFPRW--MSPDLKRFVSRLL 258 Query: 485 VGNPATRITIPEIRNHPWFLK------NLPADLVDDSTMSSQYE 372 NP TRITI EI PWF++ D ++D + S E Sbjct: 259 DINPETRITIDEILKDPWFVRGGFKQIKFHDDEIEDQKVESSLE 302
>TRIB2_PONPY (Q5R669) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/79 (43%), Positives = 45/79 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY MLVG YPF D + F K I Q++IP+ + ++C LI I Sbjct: 236 DVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRGQFNIPETLSPKAKC--LIRSIL 289 Query: 485 VGNPATRITIPEIRNHPWF 429 P+ R+T EI +HPWF Sbjct: 290 RREPSERLTSQEILDHPWF 308
>TRIB2_MOUSE (Q8K4K3) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/79 (43%), Positives = 45/79 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY MLVG YPF D + F K I Q++IP+ + ++C LI I Sbjct: 236 DVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRGQFNIPETLSPKAKC--LIRSIL 289 Query: 485 VGNPATRITIPEIRNHPWF 429 P+ R+T EI +HPWF Sbjct: 290 RREPSERLTSQEILDHPWF 308
>TRIB2_HUMAN (Q92519) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/79 (43%), Positives = 45/79 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY MLVG YPF D + F K I Q++IP+ + ++C LI I Sbjct: 236 DVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRGQFNIPETLSPKAKC--LIRSIL 289 Query: 485 VGNPATRITIPEIRNHPWF 429 P+ R+T EI +HPWF Sbjct: 290 RREPSERLTSQEILDHPWF 308
>TRIB2_CANFA (Q28283) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/79 (43%), Positives = 45/79 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY MLVG YPF D + F K I Q++IP+ + ++C LI I Sbjct: 236 DVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRGQFNIPETLSPKAKC--LIRSIL 289 Query: 485 VGNPATRITIPEIRNHPWF 429 P+ R+T EI +HPWF Sbjct: 290 RREPSERLTSQEILDHPWF 308
>TRIB2_BOVIN (Q5GLH2) Tribbles homolog 2 (TRB-2)| Length = 343 Score = 61.2 bits (147), Expect = 3e-09 Identities = 34/79 (43%), Positives = 45/79 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY MLVG YPF D + F K I Q++IP+ + ++C LI I Sbjct: 236 DVWSLGVMLYTMLVGRYPFHDIEPSSLFSK----IRRGQFNIPETLSPKAKC--LIRSIL 289 Query: 485 VGNPATRITIPEIRNHPWF 429 P+ R+T EI +HPWF Sbjct: 290 RREPSERLTSQEILDHPWF 308
>STK6L_XENLA (Q91819) Serine/threonine-protein kinase Eg2-like (EC 2.7.11.1)| (p46XlEg22) Length = 408 Score = 61.2 bits (147), Expect = 3e-09 Identities = 31/82 (37%), Positives = 45/82 (54%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV Y LVG PFE + +R RI V++ P YV S E +DL++K+ Sbjct: 318 DLWSLGVLCYEFLVGKPPFETDTHQETYR----RISKVEFQYPPYV--SEEAKDLVSKLL 371 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 NP R+ + + HPW +KN Sbjct: 372 KHNPNHRLPLKGVLEHPWIVKN 393
>KKCC2_MOUSE (Q8C078) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 4/133 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GVTLY + G PF D + +I S PD I+ + +DLI ++ Sbjct: 372 DVWAMGVTLYCFVFGQCPFMD----ERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRML 427 Query: 485 VGNPATRITIPEIRNHPWFLKN----LPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAE 318 NP +RI +PEI+ HPW ++ LP++ + + + EE E ++ + + ++ Sbjct: 428 DKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILV 487 Query: 317 ATIPAAGSRINQF 279 T+ S N F Sbjct: 488 KTMIRKRSFGNPF 500
>KKCC2_HUMAN (Q96RR4) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 588 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 4/133 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GVTLY + G PF D + +I S PD I+ + +DLI ++ Sbjct: 372 DVWAMGVTLYCFVFGQCPFMD----ERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRML 427 Query: 485 VGNPATRITIPEIRNHPWFLKN----LPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAE 318 NP +RI +PEI+ HPW ++ LP++ + + + EE E ++ + + ++ Sbjct: 428 DKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILV 487 Query: 317 ATIPAAGSRINQF 279 T+ S N F Sbjct: 488 KTMIRKRSFGNPF 500
>KKCC2_RAT (O88831) Calcium/calmodulin-dependent protein kinase kinase 2 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-kinase kinase beta) (CaM-KK beta) (CaMKK beta) Length = 587 Score = 61.2 bits (147), Expect = 3e-09 Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 4/133 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GVTLY + G PF D + +I S PD I+ + +DLI ++ Sbjct: 371 DVWAMGVTLYCFVFGQCPFMD----ERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRML 426 Query: 485 VGNPATRITIPEIRNHPWFLKN----LPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAE 318 NP +RI +PEI+ HPW ++ LP++ + + + EE E ++ + + ++ Sbjct: 427 DKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILV 486 Query: 317 ATIPAAGSRINQF 279 T+ S N F Sbjct: 487 KTMIRKRSFGNPF 499
>IPL1_YARLI (Q6C3J2) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 371 Score = 60.8 bits (146), Expect = 4e-09 Identities = 31/84 (36%), Positives = 48/84 (57%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G+ +Y L GA PFE EP + T +RI+ + IP YV S++ DLI ++ Sbjct: 277 DVWSLGILMYEFLCGAPPFE---EPGGAQATYRRIVKLDLRIPPYV--SADAADLIKRML 331 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 +PA R + ++ HPW ++ P Sbjct: 332 TLDPAKRFKLKDMHKHPWIVRLRP 355
>KCC2B_RAT (P08413) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 60.8 bits (146), Expect = 4e-09 Identities = 28/78 (35%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ K +++ + + + P++ ++ E ++LI ++ Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT E HPW Sbjct: 254 TINPAKRITAHEALKHPW 271
>KCC2B_MOUSE (P28652) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 542 Score = 60.8 bits (146), Expect = 4e-09 Identities = 28/78 (35%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ K +++ + + + P++ ++ E ++LI ++ Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT E HPW Sbjct: 254 TINPAKRITAHEALKHPW 271
>BRSK1_HUMAN (Q8TDC3) BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1| kinase) (SAD1A) Length = 794 Score = 60.8 bits (146), Expect = 4e-09 Identities = 27/83 (32%), Positives = 50/83 (60%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 R ++WSCGV L+ +LVGA PF+D N R+ ++++ + +P + I +C+ L+ Sbjct: 226 RRADMWSCGVILFALLVGALPFDD----DNLRQLLEKVKRGVFHMPHF--IPPDCQSLLR 279 Query: 494 KIFVGNPATRITIPEIRNHPWFL 426 + P R+++ +I+ HPW+L Sbjct: 280 GMIEVEPEKRLSLEQIQKHPWYL 302
>KCC2B_HUMAN (Q13554) Calcium/calmodulin-dependent protein kinase type II beta| chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II beta subunit) (CaMK-II beta subunit) Length = 664 Score = 60.8 bits (146), Expect = 4e-09 Identities = 28/78 (35%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ K +++ + + + P++ ++ E ++LI ++ Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT E HPW Sbjct: 254 TINPAKRITAHEALKHPW 271
>CDR1_SCHPO (P07334) Mitosis inducer protein kinase cdr1 (EC 2.7.11.1) (Protein| kinase nim1) Length = 593 Score = 60.8 bits (146), Expect = 4e-09 Identities = 39/116 (33%), Positives = 59/116 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV LY +L PF + + K I Y +P ISS +DL+ ++ Sbjct: 186 DVWSCGVILYSLLSNKLPFGGQNTDVIYNK----IRHGAYDLPS--SISSAAQDLLHRML 239 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAE 318 NP+TRITIPE+ +HP+ + +D +T P P S+DEI ++ + Sbjct: 240 DVNPSTRITIPEVFSHPFLMGCTSLSSMDSTT-------PPTPSLSIDEIDPLVVD 288
>IPL1_CANGA (Q6FV07) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 358 Score = 60.8 bits (146), Expect = 4e-09 Identities = 30/84 (35%), Positives = 49/84 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GV Y ++VG PFE+ + T +RIL + P+ IS + +DLI+K+ Sbjct: 279 DVWALGVLAYELVVGVPPFEENSK----ELTYKRILKCDLNFPE--SISKDAKDLISKLL 332 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 V + R+++ ++ HPW LKN P Sbjct: 333 VTDTTQRLSLTGVKTHPWILKNKP 356
>AAPK1_CAEEL (P45894) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMP-activated kinase 1) Length = 589 Score = 60.5 bits (145), Expect = 5e-09 Identities = 32/84 (38%), Positives = 46/84 (54%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY ML G PF+D + P F K I S +Y++P + + DLI+ + Sbjct: 204 DLWSCGVILYAMLCGTLPFDDQNVPTLFAK----IKSGRYTVP--YSMEKQAADLISTML 257 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 +P R + I NH WF +LP Sbjct: 258 QVDPVKRADVKRIVNHSWFRIDLP 281
>ARK1_SCHPO (O59790) Serine/threonine-protein kinase ark1 (EC 2.7.11.1)| (Aurora-related kinase 1) Length = 355 Score = 60.5 bits (145), Expect = 5e-09 Identities = 31/81 (38%), Positives = 45/81 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV Y LVGA PFED T +RI V IP +V + RDLI+++ Sbjct: 267 DLWSLGVLTYEFLVGAPPFEDMS---GHSATYKRIAKVDLKIPSFV--PPDARDLISRLL 321 Query: 485 VGNPATRITIPEIRNHPWFLK 423 NP R+++ ++ HPW +K Sbjct: 322 QHNPEKRMSLEQVMRHPWIVK 342
>STK6_RAT (P59241) Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-A)| (ratAurA) Length = 397 Score = 60.5 bits (145), Expect = 5e-09 Identities = 30/82 (36%), Positives = 48/82 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV Y LVG PFE +++T +RI V+++ PD+V + RDLI+++ Sbjct: 304 DLWSLGVLCYEFLVGMPPFE----AHTYQETYRRISRVEFTFPDFV--TEGARDLISRLL 357 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 N + R+T+ E+ HPW N Sbjct: 358 KHNSSQRLTLAEVLEHPWIKAN 379
>STK6_MOUSE (P97477) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1) Length = 395 Score = 60.5 bits (145), Expect = 5e-09 Identities = 30/82 (36%), Positives = 48/82 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV Y LVG PFE +++T +RI V+++ PD+V + RDLI+++ Sbjct: 302 DLWSLGVLCYEFLVGMPPFE----AHTYQETYRRISRVEFTFPDFV--TEGARDLISRLL 355 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 N + R+T+ E+ HPW N Sbjct: 356 KHNASQRLTLAEVLEHPWIKAN 377
>KCC2G_MOUSE (Q923T9) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 529 Score = 60.1 bits (144), Expect = 6e-09 Identities = 27/78 (34%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ K +++ + + + P++ ++ E ++LI ++ Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT + HPW Sbjct: 254 TINPAKRITADQALKHPW 271
>SNF1_YEAST (P06782) Carbon catabolite derepressing protein kinase (EC| 2.7.11.1) Length = 633 Score = 60.1 bits (144), Expect = 6e-09 Identities = 37/101 (36%), Positives = 51/101 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV LYVML PF+D P F+ I + Y++P + +S LI ++ Sbjct: 234 DVWSCGVILYVMLCRRLPFDDESIPVLFK----NISNGVYTLPKF--LSPGAAGLIKRML 287 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPE 363 + NP RI+I EI WF +LP L+ EE E Sbjct: 288 IVNPLNRISIHEIMQDDWFKVDLPEYLLPPDLKPHPEEENE 328
>KCC2G_HUMAN (Q13555) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 558 Score = 60.1 bits (144), Expect = 6e-09 Identities = 27/78 (34%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ K +++ + + + P++ ++ E ++LI ++ Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT + HPW Sbjct: 254 TINPAKRITADQALKHPW 271
>KCC2G_RAT (P11730) Calcium/calmodulin-dependent protein kinase type II gamma| chain (EC 2.7.11.17) (CaM-kinase II gamma chain) (CaM kinase II gamma subunit) (CaMK-II gamma subunit) Length = 527 Score = 60.1 bits (144), Expect = 6e-09 Identities = 27/78 (34%), Positives = 48/78 (61%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ K +++ + + + P++ ++ E ++LI ++ Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHKLYQQI--KAGAYDFPSPEWDTVTPEAKNLINQML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NPA RIT + HPW Sbjct: 254 TINPAKRITADQALKHPW 271
>BRSK2_HUMAN (Q8IWQ3) BR serine/threonine-protein kinase 2 (EC 2.7.11.1)| (Serine/threonine-protein kinase 29) (SAD1B) Length = 736 Score = 59.7 bits (143), Expect = 8e-09 Identities = 36/118 (30%), Positives = 61/118 (51%), Gaps = 2/118 (1%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 R +VWSCGV L+ +LVGA PF+D N R+ ++++ + +P + I +C+ L+ Sbjct: 195 RKADVWSCGVILFALLVGALPFDD----DNLRQLLEKVKRGVFHMPHF--IPPDCQSLLR 248 Query: 494 KIFVGNPATRITIPEIRNHPWFL--KNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQI 327 + + A R+T+ I+ H W++ KN P EPEQP+ +I + Sbjct: 249 GMSEVDAARRLTLEHIQKHIWYIGGKNEP--------------EPEQPIPRKVQIRSL 292
>TSSK3_MOUSE (Q9D2E1) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 59.7 bits (143), Expect = 8e-09 Identities = 30/78 (38%), Positives = 46/78 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYVML + PF+D D PK + + + S P ++ IS+EC+DL+ ++ Sbjct: 192 DVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGV-----SFPTHLGISTECQDLLKRLL 246 Query: 485 VGNPATRITIPEIRNHPW 432 + R +I E+ HPW Sbjct: 247 EPDMILRPSIEEVSWHPW 264
>STK6_HUMAN (O14965) Serine/threonine-protein kinase 6 (EC 2.7.11.1)| (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase) Length = 403 Score = 59.7 bits (143), Expect = 8e-09 Identities = 30/82 (36%), Positives = 47/82 (57%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV Y LVG PFE +++T +RI V+++ PD+V + RDLI+++ Sbjct: 311 DLWSLGVLCYEFLVGKPPFE----ANTYQETYKRISRVEFTFPDFV--TEGARDLISRLL 364 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 NP+ R + E+ HPW N Sbjct: 365 KHNPSQRPMLREVLEHPWITAN 386
>KCC2A_DROME (Q00168) Calcium/calmodulin-dependent protein kinase type II alpha| chain (EC 2.7.11.17) (CaM-kinase II alpha chain) Length = 530 Score = 58.9 bits (141), Expect = 1e-08 Identities = 27/78 (34%), Positives = 46/78 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV LY++LVG PF D D+ + + + + + Y P++ ++ E ++LI ++ Sbjct: 196 DIWACGVILYILLVGYPPFWDEDQHRLYSQI--KAGAYDYPSPEWDTVTPEAKNLINQML 253 Query: 485 VGNPATRITIPEIRNHPW 432 NP RIT E HPW Sbjct: 254 TVNPNKRITAAEALKHPW 271
>GIN4_YEAST (Q12263) Serine/threonine-protein kinase GIN4 (EC 2.7.11.1)| Length = 1142 Score = 58.9 bits (141), Expect = 1e-08 Identities = 30/81 (37%), Positives = 44/81 (54%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV L+ +L G PF++ D N R + ++ ++ +P IS E +DLI KI Sbjct: 213 DVWSCGVILFALLTGRLPFDEEDG--NIRTLLLKVQKGEFEMPSDDEISREAQDLIRKIL 270 Query: 485 VGNPATRITIPEIRNHPWFLK 423 +P RI +I HP K Sbjct: 271 TVDPERRIKTRDILKHPLLQK 291
>TSSK3_HUMAN (Q96PN8) Testis-specific serine/threonine-protein kinase 3 (EC| 2.7.11.1) (TSSK-3) (Testis-specific kinase 3) (TSK-3) (Serine/threonine-protein kinase 22C) Length = 268 Score = 58.9 bits (141), Expect = 1e-08 Identities = 29/78 (37%), Positives = 46/78 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYVML + PF+D D PK + + + S P ++ IS++C+DL+ ++ Sbjct: 192 DVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGV-----SFPTHLSISADCQDLLKRLL 246 Query: 485 VGNPATRITIPEIRNHPW 432 + R +I E+ HPW Sbjct: 247 EPDMILRPSIEEVSWHPW 264
>AAPK2_CAEEL (Q95ZQ4) 5'-AMP-activated protein kinase catalytic subunit alpha-2| (EC 2.7.11.1) (AMP-activated kinase 2) Length = 626 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/84 (38%), Positives = 45/84 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV LY +L G PF+D P FRK I S + PD+ + +L+ + Sbjct: 267 DVWSCGVILYALLCGTLPFDDEHVPSLFRK----IKSGVFPTPDF--LERPIVNLLHHML 320 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 +P R TI ++ H WF K+LP Sbjct: 321 CVDPMKRATIKDVIAHEWFQKDLP 344
>SNRK_RAT (Q63553) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 746 Score = 58.2 bits (139), Expect = 2e-08 Identities = 25/78 (32%), Positives = 49/78 (62%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV L++++ G PF++ ++ + T+ I+ +Y++P +S+ CRDLI ++ Sbjct: 197 DIWSLGVILFMLVCGQPPFQEANDSE----TLTMIMDCKYTVPP--RVSAGCRDLITRML 250 Query: 485 VGNPATRITIPEIRNHPW 432 +P R ++ EI +HPW Sbjct: 251 QRDPKRRASLEEIESHPW 268
>SSP1_SCHPO (P50526) Serine/threonine-protein kinase ssp1 (EC 2.7.11.1)| Length = 652 Score = 58.2 bits (139), Expect = 2e-08 Identities = 39/127 (30%), Positives = 61/127 (48%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GVTL+ +L G PF E + F K + L++ S PD I E RDL+ ++ Sbjct: 335 DVWALGVTLFCLLFGRCPFNASMEYELFDKIVNERLNIP-STPD---IGEEGRDLLKRLL 390 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 +P RIT+ E++ HPW L L ++PE+ +Q+ D E + Sbjct: 391 CKDPEQRITLVEVKLHPWTLDGL--------------KDPEKWLQNTDPSTVSRVEVSTD 436 Query: 305 AAGSRIN 285 S I+ Sbjct: 437 EVASAIS 443
>SNRK_MOUSE (Q8VDU5) SNF-related serine/threonine-protein kinase (EC 2.7.11.1)| (SNF1-related kinase) Length = 748 Score = 58.2 bits (139), Expect = 2e-08 Identities = 25/78 (32%), Positives = 49/78 (62%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV L++++ G PF++ ++ + T+ I+ +Y++P +S+ CRDLI ++ Sbjct: 197 DIWSLGVILFMLVCGQPPFQEANDSE----TLTMIMDCKYTVPP--RVSAGCRDLITRML 250 Query: 485 VGNPATRITIPEIRNHPW 432 +P R ++ EI +HPW Sbjct: 251 QRDPKRRASLEEIESHPW 268
>KK31_SCHPO (Q9HFF4) Probable serine/threonine-protein kinase C110.01 (EC| 2.7.11.1) Length = 1023 Score = 58.2 bits (139), Expect = 2e-08 Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPF-EDPDEP--KNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++WSCGV LY ML G PF +DP P +N + + I S P++ S+ RD++ Sbjct: 695 DIWSCGVILYAMLAGYLPFDDDPHNPNGENVPRLYRYICSTPLIFPEF--FKSKARDILK 752 Query: 494 KIFVGNPATRITIPEIRNHPW 432 KI V +PA R+ + I NH + Sbjct: 753 KILVPDPAKRVRMSAIMNHAY 773
>CSKP_HUMAN (O14936) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog) Length = 926 Score = 57.4 bits (137), Expect = 4e-08 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIAK 492 +VW CGV L+++L G PF E + + I+ +Y + + HIS +DL+ + Sbjct: 201 DVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKGKYKMNPRQWSHISESAKDLVRR 255 Query: 491 IFVGNPATRITIPEIRNHPW 432 + + +PA RIT+ E NHPW Sbjct: 256 MLMLDPAERITVYEALNHPW 275
>CSKP_MOUSE (O70589) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 924 Score = 57.4 bits (137), Expect = 4e-08 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIAK 492 +VW CGV L+++L G PF E + + I+ +Y + + HIS +DL+ + Sbjct: 201 DVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKGKYKMNPRQWSHISESAKDLVRR 255 Query: 491 IFVGNPATRITIPEIRNHPW 432 + + +PA RIT+ E NHPW Sbjct: 256 MLMLDPAERITVYEALNHPW 275
>STK11_XENLA (Q91604) Serine/threonine-protein kinase 11 (EC 2.7.11.1)| (Serine/threonine-protein kinase XEEK1) (Egg and embryo kinase 1) Length = 432 Score = 57.4 bits (137), Expect = 4e-08 Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 4/88 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GVTLY + G YPFE N K + I YSIP+ EC L++ + Sbjct: 240 DIWSAGVTLYNITTGLYPFEG----DNIYKLFENIGKGDYSIPE------ECGPLLSDLL 289 Query: 485 VG----NPATRITIPEIRNHPWFLKNLP 414 G +PA R +I +IR H WF K P Sbjct: 290 RGMLEYDPAKRFSIQQIRQHNWFRKKHP 317
>CSKP_RAT (Q62915) Peripheral plasma membrane protein CASK (EC 2.7.11.1)| (Calcium/calmodulin-dependent serine protein kinase) Length = 909 Score = 57.4 bits (137), Expect = 4e-08 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 2/80 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIAK 492 +VW CGV L+++L G PF E + + I+ +Y + + HIS +DL+ + Sbjct: 201 DVWGCGVILFILLSGCLPFYGTKE-----RLFEGIIKGKYKMNPRQWSHISESAKDLVRR 255 Query: 491 IFVGNPATRITIPEIRNHPW 432 + + +PA RIT+ E NHPW Sbjct: 256 MLMLDPAERITVYEALNHPW 275
>CIPK1_ARATH (Q8RWC9) CBL-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (SOS2-like protein kinase PKS13) (SNF1-related kinase 3.16) Length = 444 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 1/91 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LYV+L G PF+D +N Q+I IP + +S R +I ++ Sbjct: 203 DIWSCGVILYVILTGCLPFDD----RNLAVLYQKICKGDPPIPRW--LSPGARTMIKRML 256 Query: 485 VGNPATRITIPEIRNHPWF-LKNLPADLVDD 396 NP TRIT+ I+ WF L+ +P+ DD Sbjct: 257 DPNPVTRITVVGIKASEWFKLEYIPSIPDDD 287
>AAPK1_RAT (P54645) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/128 (28%), Positives = 60/128 (46%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY +L G PF+D P F+K I + P Y++ S L+ + Sbjct: 196 DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI----FYTPQYLNPS--VISLLKHML 249 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 +P R TI +IR H WF ++LP L + S ++ ++ + E + E + Sbjct: 250 QVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 309 Query: 305 AAGSRINQ 282 +R +Q Sbjct: 310 CLYNRNHQ 317
>AAPK1_PONPY (Q5RDH5) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/128 (28%), Positives = 60/128 (46%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY +L G PF+D P F+K I + P Y++ S L+ + Sbjct: 198 DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI----FYTPQYLNPS--VISLLKHML 251 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 +P R TI +IR H WF ++LP L + S ++ ++ + E + E + Sbjct: 252 QVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 311 Query: 305 AAGSRINQ 282 +R +Q Sbjct: 312 CLYNRNHQ 319
>AAPK1_HUMAN (Q13131) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 550 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/128 (28%), Positives = 60/128 (46%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY +L G PF+D P F+K I + P Y++ S L+ + Sbjct: 198 DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI----FYTPQYLNPS--VISLLKHML 251 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 +P R TI +IR H WF ++LP L + S ++ ++ + E + E + Sbjct: 252 QVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 311 Query: 305 AAGSRINQ 282 +R +Q Sbjct: 312 CLYNRNHQ 319
>ICL1_KLULA (Q6CWQ4) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 361 Score = 56.6 bits (135), Expect = 7e-08 Identities = 28/82 (34%), Positives = 46/82 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GV Y +LVG+ PFE+ + +R RIL P +++S + RDLI ++ Sbjct: 279 DVWALGVLTYELLVGSPPFEEDTKEMTYR----RILRCDLKFP--LNVSPQARDLIVRLL 332 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 P+ RI + E+++H W N Sbjct: 333 QFEPSKRIPLSEVKSHAWIANN 354
>KKCC1_RAT (P97756) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (alpha CaMKK) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 56.6 bits (135), Expect = 7e-08 Identities = 35/106 (33%), Positives = 52/106 (49%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GVTLY + G PF D RK I + P+ +S E +DLI K+ Sbjct: 335 DVWATGVTLYCFVYGKCPFIDEYILALHRK----IKNEAVVFPEEPEVSEELKDLILKML 390 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQS 348 NP TRI + +I+ HPW K+ L + S E E+ +++ Sbjct: 391 DKNPETRIGVSDIKLHPWVTKHGEEPLPSEEEHCSVVEVTEEEVKN 436
>KIN4_YEAST (Q01919) Serine/threonine-protein kinase KIN4 (EC 2.7.11.1)| Length = 800 Score = 56.2 bits (134), Expect = 9e-08 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDE---PKNFRKTIQRILSVQYSIPDYVHISSECRD 504 R +VWSCGV LY ML G P++D E + + + I P+Y I+ RD Sbjct: 231 RKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEY--ITPIPRD 288 Query: 503 LIAKIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP 357 L+ +I V NP RI + I+ H W LK A L ++ + E+P Sbjct: 289 LLRRILVPNPRRRINLQTIKRHVW-LKPHEAFLSIQPNYWDEHLQKERP 336
>PLK4_HUMAN (O00444) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 970 Score = 55.8 bits (133), Expect = 1e-07 Identities = 30/98 (30%), Positives = 52/98 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G Y +L+G PF D D KN T+ +++ Y +P ++ I E +DLI ++ Sbjct: 193 DVWSLGCMFYTLLIGRPPF-DTDTVKN---TLNKVVLADYEMPTFLSI--EAKDLIHQLL 246 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYE 372 NPA R+++ + +HP+ +N D T+ + Sbjct: 247 RRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSID 284
>YP141_YEAST (Q03002) Putative serine/threonine-protein kinase YPL141C (EC| 2.7.11.1) Length = 865 Score = 55.5 bits (132), Expect = 1e-07 Identities = 30/84 (35%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPF-EDPDEPK--NFRKTIQRILSVQYSIPDYVHISSECRD 504 R ++WSCGV LY +L G P+ +DP+ P+ + + I S PDY I RD Sbjct: 231 RKADIWSCGVILYAILAGYLPWDDDPNNPEGSDIGRLYNYINSTPLKFPDY--ILPIPRD 288 Query: 503 LIAKIFVGNPATRITIPEIRNHPW 432 L+ ++ V +P RI + +I+ H W Sbjct: 289 LLRRMLVSDPKKRINLKQIKKHEW 312
>AURKB_MOUSE (O70126) Serine/threonine-protein kinase 12 (EC 2.7.11.1)| (Aurora-related kinase 2) (Serine/threonine-protein kinase 5) (STK-1) (Aurora-B) Length = 345 Score = 55.5 bits (132), Expect = 1e-07 Identities = 27/82 (32%), Positives = 43/82 (52%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W GV Y ++VG PFE P + +R+ ++ L S+P S +DLI+K+ Sbjct: 260 DLWCIGVLCYELMVGNPPFESPSHSETYRRIVKVDLKFPSSVP------SGAQDLISKLL 313 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 NP R+ + E+ HPW N Sbjct: 314 KHNPWQRLPLAEVAAHPWVRAN 335
>KKCC1_MOUSE (Q8VBY2) Calcium/calmodulin-dependent protein kinase kinase 1 (EC| 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase) Length = 505 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/107 (29%), Positives = 56/107 (52%), Gaps = 1/107 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI-PDYVHISSECRDLIAKI 489 +VW+ GVTLY + G PF D ++ T+ R + + + P+ +S + +DLI ++ Sbjct: 335 DVWATGVTLYCFVYGKCPFID-----DYILTLHRKIKNEAVVFPEEPEVSEDLKDLILRM 389 Query: 488 FVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQS 348 NP TRI + +I+ HPW K+ L + S E E+ +++ Sbjct: 390 LDKNPETRIGVSDIKLHPWVTKHGEEPLPSEEEHCSVVEVTEEEVKN 436
>TSSK1_MOUSE (Q61241) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 364 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/107 (31%), Positives = 58/107 (54%), Gaps = 4/107 (3%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKT-IQRILSVQYSIPDYVHISSECRDLI 498 ++ ++WS GV LY+M+ G+ P++D N +K IQ+ V + P H++ EC+DLI Sbjct: 195 KVYDIWSLGVILYIMVCGSMPYDD----SNIKKLRIQKEHRVNF--PRSKHLTGECKDLI 248 Query: 497 AKIFVGNPATRITIPEIRNHPWF---LKNLPADLVDDSTMSSQYEEP 366 ++ + R+ I EI NH W + L + ++ SS+ EP Sbjct: 249 YRMLQPDVNRRLHIDEILNHCWVQPKARGLSSGAINKEGESSRATEP 295
>CDPK2_ORYSA (P53683) Calcium-dependent protein kinase, isoform 2 (EC 2.7.11.1)| (CDPK 2) Length = 533 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/99 (30%), Positives = 48/99 (48%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY++L G PF E F +Q + + + IS +DL+ K+ Sbjct: 267 DVWSAGVILYILLSGVPPFWAETEKGIFDAILQG--EIDFESQPWPSISESAKDLVRKML 324 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEE 369 +P RIT ++ HPW +D DS + S+ ++ Sbjct: 325 TQDPKKRITSAQVLQHPWLRDGEASDKPIDSAVLSRMKQ 363
>IPL1_YEAST (P38991) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) (Increase-in-ploidy protein 1) Length = 367 Score = 55.1 bits (131), Expect = 2e-07 Identities = 29/84 (34%), Positives = 50/84 (59%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 + W+ GV + +L GA PFE+ E K+ T +RI ++ +P +IS + +DLI K+ Sbjct: 283 DAWALGVLAFELLTGAPPFEE--EMKD--TTYKRIAALDIKMPS--NISQDAQDLILKLL 336 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 +P R+ + +++ HPW L+N P Sbjct: 337 KYDPKDRMRLGDVKMHPWILRNKP 360
>AAPK1_MOUSE (Q5EG47) 5'-AMP-activated protein kinase catalytic subunit alpha-1| (EC 2.7.11.1) (AMPK alpha-1 chain) Length = 548 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/128 (27%), Positives = 59/128 (46%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY +L G PF+D P F+K I + P Y++ S L+ + Sbjct: 196 DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGI----FYTPQYLNPS--VISLLKHML 249 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 +P R I +IR H WF ++LP L + S ++ ++ + E + E + Sbjct: 250 QVDPMKRAAIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS 309 Query: 305 AAGSRINQ 282 +R +Q Sbjct: 310 CLYNRNHQ 317
>PLK4_MOUSE (Q64702) Serine/threonine-protein kinase PLK4 (EC 2.7.11.21)| (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine-protein kinase 18) Length = 925 Score = 54.7 bits (130), Expect = 3e-07 Identities = 27/82 (32%), Positives = 48/82 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS G Y +L+G PF D D KN T+ +++ Y +P + +S E +DLI ++ Sbjct: 193 DIWSLGCMFYTLLIGRPPF-DTDTVKN---TLNKVVLADYEMPAF--LSREAQDLIHQLL 246 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 NPA R+++ + +HP+ +N Sbjct: 247 RRNPADRLSLSSVLDHPFMSRN 268
>MARK2_MOUSE (Q05512) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 776 Score = 54.7 bits (130), Expect = 3e-07 Identities = 27/78 (34%), Positives = 47/78 (60%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y IP Y+ S++C +L+ K Sbjct: 232 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRIPFYM--STDCENLLKKFL 285 Query: 485 VGNPATRITIPEIRNHPW 432 + NP+ R T+ +I W Sbjct: 286 ILNPSKRGTLEQIMKDRW 303
>MARK2_RAT (O08679) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1) Length = 722 Score = 54.7 bits (130), Expect = 3e-07 Identities = 27/78 (34%), Positives = 47/78 (60%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y IP Y+ S++C +L+ K Sbjct: 232 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRIPFYM--STDCENLLKKFL 285 Query: 485 VGNPATRITIPEIRNHPW 432 + NP+ R T+ +I W Sbjct: 286 ILNPSKRGTLEQIMKDRW 303
>TSSK1_HUMAN (Q9BXA7) Testis-specific serine/threonine-protein kinase 1 (EC| 2.7.11.1) (TSSK-1) (Testis-specific kinase 1) (TSK-1) (Serine/threonine-protein kinase 22A) Length = 367 Score = 54.7 bits (130), Expect = 3e-07 Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 3/106 (2%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ ++WS GV LY+M+ G+ P++D N +K ++ + + P H++ EC+DLI Sbjct: 195 KVYDIWSLGVILYIMVCGSMPYDD----SNIKKMLRIQKEHRVNFPRSKHLTGECKDLIY 250 Query: 494 KIFVGNPATRITIPEIRNHPWF---LKNLPADLVDDSTMSSQYEEP 366 + + R+ I EI +H W + P+ ++ SS+ EP Sbjct: 251 HMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEP 296
>MARK2_HUMAN (Q7KZI7) Serine/threonine-protein kinase MARK2 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog) Length = 788 Score = 54.7 bits (130), Expect = 3e-07 Identities = 27/78 (34%), Positives = 47/78 (60%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y IP Y+ S++C +L+ K Sbjct: 232 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRIPFYM--STDCENLLKKFL 285 Query: 485 VGNPATRITIPEIRNHPW 432 + NP+ R T+ +I W Sbjct: 286 ILNPSKRGTLEQIMKDRW 303
>IPL1_CANAL (Q59S66) Spindle assembly checkpoint kinase (EC 2.7.11.1) (Aurora| kinase) Length = 530 Score = 54.3 bits (129), Expect = 3e-07 Identities = 28/84 (33%), Positives = 46/84 (54%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ G+ Y +LVG PFE N T ++I V P + + + DLI+K+ Sbjct: 445 DIWALGILCYELLVGKPPFE----AINRNITYEKIAKVDIKYPSNLDV--DAIDLISKLV 498 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 V +P R+++ E+ NH W +KN P Sbjct: 499 VKDPNKRLSLKEVLNHNWIIKNKP 522
>DUN1_YEAST (P39009) DNA damage response protein kinase DUN1 (EC 2.7.11.1)| Length = 513 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/79 (39%), Positives = 40/79 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LYV L G PF D P + ++ I + YS P + I LI+ + Sbjct: 403 DLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYS-PYWDKIDDSVLHLISNLL 461 Query: 485 VGNPATRITIPEIRNHPWF 429 V NP R I E NHPWF Sbjct: 462 VLNPDERYNIDEALNHPWF 480
>MARK4_MOUSE (Q8CIP4) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| Length = 752 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/102 (28%), Positives = 53/102 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY ++ G+ PF+ N ++ +R+L +Y +P Y+ S++C ++ + Sbjct: 238 DIWSLGVILYTLVSGSLPFDG----HNLKELRERVLRGKYRVPFYM--STDCESILRRFL 291 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQ 360 V NPA R T+ +I W ++ + Y EPE+ Sbjct: 292 VLNPAKRCTLEQIMKDKWI------NIGYEGEELKPYTEPEE 327
>MARK4_HUMAN (Q96L34) MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase-like 1) Length = 752 Score = 54.3 bits (129), Expect = 3e-07 Identities = 29/102 (28%), Positives = 53/102 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY ++ G+ PF+ N ++ +R+L +Y +P Y+ S++C ++ + Sbjct: 238 DIWSLGVILYTLVSGSLPFDG----HNLKELRERVLRGKYRVPFYM--STDCESILRRFL 291 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQ 360 V NPA R T+ +I W ++ + Y EPE+ Sbjct: 292 VLNPAKRCTLEQIMKDKWI------NIGYEGEELKPYTEPEE 327
>AURKB_RAT (O55099) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora-B) Length = 343 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/82 (31%), Positives = 44/82 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W GV Y ++VG PFE P + +R RI+ V P + + + +DLI+K+ Sbjct: 258 DLWCIGVLCYELMVGNPPFESPSHSETYR----RIVKVDLKFPSSMPLGA--KDLISKLL 311 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 NP+ R+ + ++ HPW N Sbjct: 312 KHNPSQRLPLEQVSAHPWVRAN 333
>CDPK_DAUCA (P28582) Calcium-dependent protein kinase (EC 2.7.11.1) (CDPK)| Length = 532 Score = 53.9 bits (128), Expect = 4e-07 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 1/118 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY++L G PF +E F ++ + + + + +S+ +DL+ K+ Sbjct: 263 DIWSAGVILYILLSGVPPFWAENEKGIFDAILEGV--IDFESEPWPSVSNSAKDLVRKML 320 Query: 485 VGNPATRITIPEIRNHPWFLKNLPA-DLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 +P RIT ++ +HPW + A D DS + S+ ++ + ++++AE+ Sbjct: 321 TQDPRRRITSAQVLDHPWMREGGEASDKPIDSAVLSRMKQFRAMNKLKQLALKVIAES 378
>WIS1_SCHPO (P33886) Protein kinase wis1 (EC 2.7.12.2) (Protein kinase sty2)| Length = 605 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 4/91 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSV----QYSIPDYVHISSECRDLI 498 +VWS G+T+ M +GAYP+ P+++ ++ ++ S+PD S E RD + Sbjct: 503 DVWSLGLTILEMALGAYPYP----PESYTSIFAQLSAICDGDPPSLPD--SFSPEARDFV 556 Query: 497 AKIFVGNPATRITIPEIRNHPWFLKNLPADL 405 K NP+ R E+ NHPW LK AD+ Sbjct: 557 NKCLNKNPSLRPDYHELANHPWLLKYQNADV 587
>MARK1_RAT (O08678) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 793 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/110 (28%), Positives = 56/110 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y +P Y +S++C +L+ K+ Sbjct: 239 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRVPFY--MSTDCENLLKKLL 292 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEI 336 V NP R ++ +I W ++ + Y EPE + I Sbjct: 293 VLNPIKRGSLEQIMKDRWM------NVGHEEEELKPYSEPELDLNDAKRI 336
>MARK1_MOUSE (Q8VHJ5) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) (ELKL motif serine/threonine-protein kinase 3) Length = 795 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/110 (28%), Positives = 56/110 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y +P Y +S++C +L+ K+ Sbjct: 239 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRVPFY--MSTDCENLLKKLL 292 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEI 336 V NP R ++ +I W ++ + Y EPE + I Sbjct: 293 VLNPIKRGSLEQIMKDRWM------NVGHEEEELKPYSEPELDLNDAKRI 336
>MKNK1_BOVIN (Q58D94) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 420 Score = 53.9 bits (128), Expect = 4e-07 Identities = 47/152 (30%), Positives = 68/152 (44%), Gaps = 36/152 (23%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFE---------DPDEPKNF--RKTIQRILSVQYSIPD--YVH 525 ++WS GV LY+ML G PF D E K + I +Y PD + H Sbjct: 230 DLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCTVCQNKLFESIQKGKYEFPDKDWAH 289 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFL-----KNLPADLV---DDSTMS----- 384 IS+E +DLI+K+ V + R++ ++ HPW + LP V + STM Sbjct: 290 ISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPERGLPTPQVLQRNSSTMDLTLFA 349 Query: 383 ----------SQYEEPEQPMQSMDEIMQILAE 318 SQ+EE EQ + E ++LAE Sbjct: 350 AEAIALNRQLSQHEENEQ--NKLAEESEVLAE 379
>TSSK2_HUMAN (Q96PF2) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) (DiGeorge syndrome protein G) Length = 358 Score = 53.9 bits (128), Expect = 4e-07 Identities = 28/81 (34%), Positives = 49/81 (60%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ ++WS GV LY+M+ G+ P++D D K R IQ+ V + P +++ EC+DLI Sbjct: 195 KVYDIWSLGVILYIMVCGSMPYDDSDIRKMLR--IQKEHRVDF--PRSKNLTCECKDLIY 250 Query: 494 KIFVGNPATRITIPEIRNHPW 432 ++ + + R+ I EI +H W Sbjct: 251 RMLQPDVSQRLHIDEILSHSW 271
>MARK3_MOUSE (Q03141) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (MPK-10) (ELKL motif kinase 2) Length = 753 Score = 53.5 bits (127), Expect = 6e-07 Identities = 27/78 (34%), Positives = 46/78 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y IP Y +S++C +L+ + Sbjct: 235 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRIPFY--MSTDCENLLKRFL 288 Query: 485 VGNPATRITIPEIRNHPW 432 V NP R T+ +I W Sbjct: 289 VLNPVKRGTLEQIMKDRW 306
>MYLK_DICDI (P25323) Myosin light chain kinase (EC 2.7.11.18) (MLCK)| Length = 295 Score = 53.5 bits (127), Expect = 6e-07 Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 2/104 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPD--YVHISSECRDLIAK 492 ++WS GV Y++L G PF P+ F ++I+ Y P+ + IS E +D I K Sbjct: 189 DMWSIGVITYILLCGFPPFYGDTVPEIF----EQIMEANYEFPEEYWGGISKEAKDFIGK 244 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQ 360 + V + + R+ NHPW N + +D M E ++ Sbjct: 245 LLVVDVSKRLNATNALNHPWLKSNNSNNTIDTVKMKEYIVERQK 288
>ST17A_RABIT (Q9GM70) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Length = 397 Score = 53.5 bits (127), Expect = 6e-07 Identities = 34/126 (26%), Positives = 54/126 (42%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV YVML G PF ++ + F Q +++ YS ++ +S D I K+ Sbjct: 228 DMWSIGVLTYVMLTGISPFLGDNKQETFLNISQ--MNLSYSEEEFDTVSESAVDFIKKLL 285 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEATIP 306 V P R T E HPW + + + D + E +Q D + +I + P Sbjct: 286 VKKPEDRATAEECLKHPWLTQ---SSIQDPVLRVKEALEEANALQKGDSVPEISSATEKP 342 Query: 305 AAGSRI 288 I Sbjct: 343 GTEESI 348
>MARK3_RAT (Q8VHF0) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| Length = 797 Score = 53.5 bits (127), Expect = 6e-07 Identities = 27/78 (34%), Positives = 46/78 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y IP Y +S++C +L+ + Sbjct: 235 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRIPFY--MSTDCENLLKRFL 288 Query: 485 VGNPATRITIPEIRNHPW 432 V NP R T+ +I W Sbjct: 289 VLNPVKRGTLEQIMKDRW 306
>MKNK1_HUMAN (Q9BUB5) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 465 Score = 53.5 bits (127), Expect = 6e-07 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 13/97 (13%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDP-------DEPKNFR----KTIQRILSVQYSIPD--YVH 525 ++WS GV LY+ML G PF D + R K + I +Y PD + H Sbjct: 283 DLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAH 342 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFLKNLP 414 ISSE +DLI+K+ V + R++ ++ HPW P Sbjct: 343 ISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAP 379
>MARK1_HUMAN (Q9P0L2) Serine/threonine-protein kinase MARK1 (EC 2.7.11.1)| (MAP/microtubule affinity-regulating kinase 1) Length = 795 Score = 53.5 bits (127), Expect = 6e-07 Identities = 27/78 (34%), Positives = 47/78 (60%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y IP Y +S++C +L+ K+ Sbjct: 239 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRIPFY--MSTDCENLLKKLL 292 Query: 485 VGNPATRITIPEIRNHPW 432 V NP R ++ +I W Sbjct: 293 VLNPIKRGSLEQIMKDRW 310
>KS6B1_RAT (P67999) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 53.5 bits (127), Expect = 6e-07 Identities = 37/122 (30%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS G +Y ML GA PF +N +KTI +IL + ++P Y ++ E RDL+ K+ Sbjct: 277 WSLGALMYDMLTGAPPFTG----ENRKKTIDKILKCKLNLPPY--LTQEARDLLKKLLKR 330 Query: 479 NPATRI-----TIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP-MQSMDEIMQILAE 318 N A+R+ E++ HP+F + + ++ + E P +P +QS +++ Q ++ Sbjct: 331 NAASRLGAGPGDAGEVQAHPFF-----RHINWEELLARKVEPPFKPLLQSEEDVSQFDSK 385 Query: 317 AT 312 T Sbjct: 386 FT 387
>KS6B1_RABIT (P67998) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 53.5 bits (127), Expect = 6e-07 Identities = 37/122 (30%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS G +Y ML GA PF +N +KTI +IL + ++P Y ++ E RDL+ K+ Sbjct: 277 WSLGALMYDMLTGAPPFTG----ENRKKTIDKILKCKLNLPPY--LTQEARDLLKKLLKR 330 Query: 479 NPATRI-----TIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP-MQSMDEIMQILAE 318 N A+R+ E++ HP+F + + ++ + E P +P +QS +++ Q ++ Sbjct: 331 NAASRLGAGPGDAGEVQAHPFF-----RHINWEELLARKVEPPFKPLLQSEEDVSQFDSK 385 Query: 317 AT 312 T Sbjct: 386 FT 387
>KS6B1_MOUSE (Q8BSK8) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (p70-S6K) Length = 525 Score = 53.5 bits (127), Expect = 6e-07 Identities = 37/122 (30%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS G +Y ML GA PF +N +KTI +IL + ++P Y ++ E RDL+ K+ Sbjct: 277 WSLGALMYDMLTGAPPFTG----ENRKKTIDKILKCKLNLPPY--LTQEARDLLKKLLKR 330 Query: 479 NPATRI-----TIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP-MQSMDEIMQILAE 318 N A+R+ E++ HP+F + + ++ + E P +P +QS +++ Q ++ Sbjct: 331 NAASRLGAGPGDAGEVQAHPFF-----RHINWEELLARKVEPPFKPLLQSEEDVSQFDSK 385 Query: 317 AT 312 T Sbjct: 386 FT 387
>KS6B1_HUMAN (P23443) Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1)| (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (p70-alpha) Length = 525 Score = 53.5 bits (127), Expect = 6e-07 Identities = 37/122 (30%), Positives = 65/122 (53%), Gaps = 6/122 (4%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS G +Y ML GA PF +N +KTI +IL + ++P Y ++ E RDL+ K+ Sbjct: 277 WSLGALMYDMLTGAPPFTG----ENRKKTIDKILKCKLNLPPY--LTQEARDLLKKLLKR 330 Query: 479 NPATRI-----TIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP-MQSMDEIMQILAE 318 N A+R+ E++ HP+F + + ++ + E P +P +QS +++ Q ++ Sbjct: 331 NAASRLGAGPGDAGEVQAHPFF-----RHINWEELLARKVEPPFKPLLQSEEDVSQFDSK 385 Query: 317 AT 312 T Sbjct: 386 FT 387
>CDR2_SCHPO (P87050) Mitosis inducer protein kinase cdr2 (EC 2.7.11.1)| Length = 775 Score = 53.1 bits (126), Expect = 7e-07 Identities = 24/78 (30%), Positives = 46/78 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCG+ + +L G PF+D N R + ++ Q+ +P +IS + + L+ ++ Sbjct: 190 DIWSCGIIFFALLTGKLPFDD----DNIRSLLLKVCQGQFEMPS--NISPQAQHLLYRML 243 Query: 485 VGNPATRITIPEIRNHPW 432 + +TRIT+ +IR HP+ Sbjct: 244 DVDSSTRITMEQIREHPF 261
>PAK1_YEAST (P38990) Serine/threonine-protein kinase PAK1 (EC 2.7.11.1)| Length = 1142 Score = 53.1 bits (126), Expect = 7e-07 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 12/111 (10%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRK---------TIQRILSVQYSIPDYVHISSE 513 ++W+ GVTLY +L G PF E K F K T + I S + S Sbjct: 361 DIWAVGVTLYCLLFGMLPFFSDFELKLFEKIVNDPLKFPTFKEIQSNKVSKVSCEEEYEM 420 Query: 512 CRDLIAKIFVGNPATRITIPEIRNHP---WFLKNLPADLVDDSTMSSQYEE 369 +DL+ K+ NP R+TIP I+ HP W ++P + D+ +SS E+ Sbjct: 421 AKDLLLKLLEKNPQKRMTIPAIKKHPFVSWDFDHVPEN--DEKLLSSVLEQ 469
>MARK3_HUMAN (P27448) MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1)| (Cdc25C-associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10) Length = 776 Score = 53.1 bits (126), Expect = 7e-07 Identities = 27/78 (34%), Positives = 46/78 (58%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LY ++ G+ PF+ +N ++ +R+L +Y IP Y +S++C +L+ + Sbjct: 258 DVWSLGVILYTLVSGSLPFDG----QNLKELRERVLRGKYRIPFY--MSTDCENLLKRFL 311 Query: 485 VGNPATRITIPEIRNHPW 432 V NP R T+ +I W Sbjct: 312 VLNPIKRGTLEQIMKDRW 329
>STK11_HUMAN (Q15831) Serine/threonine-protein kinase 11 (EC 2.7.11.1)| (Serine/threonine-protein kinase LKB1) (NY-REN-19 antigen) Length = 433 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/84 (36%), Positives = 40/84 (47%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GVTLY + G YPFE N K + I Y+IP DL+ + Sbjct: 237 DIWSAGVTLYNITTGLYPFEG----DNIYKLFENIGKGSYAIPG--DCGPPLSDLLKGML 290 Query: 485 VGNPATRITIPEIRNHPWFLKNLP 414 PA R +I +IR H WF K P Sbjct: 291 EYEPAKRFSIRQIRQHSWFRKKHP 314
>MKNK1_RAT (Q4G050) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 413 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 13/97 (13%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFE---------DPDEPKNF--RKTIQRILSVQYSIPD--YVH 525 ++WS GV LY+ML G PF D E K + I +Y PD + H Sbjct: 230 DLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYEFPDKDWAH 289 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFLKNLP 414 IS+E +DLI+K+ V + R++ ++ HPW P Sbjct: 290 ISTEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAP 326
>MKNK1_MOUSE (O08605) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 427 Score = 52.8 bits (125), Expect = 1e-06 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 13/97 (13%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFE---------DPDEPKNF--RKTIQRILSVQYSIPD--YVH 525 ++WS GV LY+ML G PF D E K + I +Y PD + H Sbjct: 242 DLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYEFPDKDWAH 301 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFLKNLP 414 IS+E +DLI+K+ V + R++ ++ HPW P Sbjct: 302 ISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAP 338
>KSG1_SCHPO (Q12701) Serine/threonine-protein kinase ksg1 (EC 2.7.11.1)| Length = 592 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/79 (39%), Positives = 42/79 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ G L+ ML G PF +E F Q IL + Y IP IS DLI K+ Sbjct: 294 DIWAFGCILFQMLAGKPPFVAGNEYLTF----QSILHLSYEIPP--DISDVASDLIKKLL 347 Query: 485 VGNPATRITIPEIRNHPWF 429 V +P R+T+ EI HP+F Sbjct: 348 VLDPKDRLTVDEIHQHPFF 366
>CDPK1_ARATH (Q06850) Calcium-dependent protein kinase, isoform AK1 (EC| 2.7.11.1) (CDPK) Length = 610 Score = 52.0 bits (123), Expect = 2e-06 Identities = 32/118 (27%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV +Y++L G PF E F + + L +S + IS +DL+ K+ Sbjct: 332 DVWSAGVIVYILLSGVPPFWAETEQGIFEQVLHGDLD--FSSDPWPSISESAKDLVRKML 389 Query: 485 VGNPATRITIPEIRNHPWF-LKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEA 315 V +P R+T ++ HPW + + D DS + S+ ++ + ++++AE+ Sbjct: 390 VRDPKKRLTAHQVLCHPWVQVDGVAPDKPLDSAVLSRMKQFSAMNKFKKMALRVIAES 447
>CCAMK_LILLO (Q43531) Calcium and calcium/calmodulin-dependent| serine/threonine-protein kinase (EC 2.7.11.17) (LlCCaMK) Length = 520 Score = 52.0 bits (123), Expect = 2e-06 Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 2/82 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYV--HISSECRDLIAK 492 ++WS GV LY++L G PF P R+ QRIL+ +S ++ I+S +DLI+ Sbjct: 226 DMWSLGVILYILLSGCPPFHAPSN----REKQQRILAGDFSFEEHTWKTITSSAKDLISS 281 Query: 491 IFVGNPATRITIPEIRNHPWFL 426 + +P R T ++ HPW + Sbjct: 282 LLSVDPYKRPTANDLLKHPWVI 303
>TSSK2_MOUSE (O54863) Testis-specific serine/threonine-protein kinase 2 (EC| 2.7.11.1) (TSSK-2) (Testis-specific kinase 2) (TSK-2) (Serine/threonine-protein kinase 22B) Length = 357 Score = 52.0 bits (123), Expect = 2e-06 Identities = 28/81 (34%), Positives = 47/81 (58%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 ++ ++WS GV LY+M+ G+ P++D D K IQ+ V + P +++ EC+DLI Sbjct: 195 KVYDIWSLGVILYIMVCGSMPYDDSDIKK---LRIQKEHRVDF--PRSKNLTGECKDLIY 249 Query: 494 KIFVGNPATRITIPEIRNHPW 432 +I + R+ I EI +H W Sbjct: 250 RILQPDVNRRLHIDEILSHSW 270
>CPK15_ARATH (P92937) CBL-interacting serine/threonine-protein kinase 15 (EC| 2.7.11.1) (Serine/threonine-protein kinase ATPK10) (SOS2-like protein kinase PKS3) (SOS-interacting protein 2) (SNF1-related kinase 3.1) Length = 421 Score = 52.0 bits (123), Expect = 2e-06 Identities = 27/87 (31%), Positives = 46/87 (52%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCGV L+V+L G PF D N + ++I + P++ ++ + L+ +I Sbjct: 194 DVWSCGVILFVLLAGYLPFRD----SNLMELYKKIGKAEVKFPNW--LAPGAKRLLKRIL 247 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADL 405 NP TR++ +I WF K L ++ Sbjct: 248 DPNPNTRVSTEKIMKSSWFRKGLQEEV 274
>MAPK5_HUMAN (Q8IW41) MAP kinase-activated protein kinase 5 (EC 2.7.11.1)| (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (p38-regulated/activated protein kinase) Length = 473 Score = 51.6 bits (122), Expect = 2e-06 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 3/81 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQR-ILSVQYSIPD--YVHISSECRDLIA 495 ++WS GV +YVML G PF + K ++R I++ + P+ + IS +D++ Sbjct: 223 DLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRRKIMTGSFEFPEEEWSQISEMAKDVVR 282 Query: 494 KIFVGNPATRITIPEIRNHPW 432 K+ P R+TI + +HPW Sbjct: 283 KLLKVKPEERLTIEGVLDHPW 303
>TSSK4_MOUSE (Q9D411) Testis-specific serine/threonine-protein kinase 4 (EC| 2.7.11.1) (TSSK-4) (Testis-specific kinase 4) (TSK-4) Length = 328 Score = 51.6 bits (122), Expect = 2e-06 Identities = 29/86 (33%), Positives = 46/86 (53%) Frame = -2 Query: 671 LRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAK 492 L + WS GV LY ++V PF+D + K R+T + + + P + IS EC++LI + Sbjct: 219 LSDTWSMGVILYTLVVARLPFDDTNLKKLLRETQKEV-----TFPANLTISQECKNLILQ 273 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLP 414 + + R TI ++ PW LK P Sbjct: 274 L-LRQSTKRATILDVLRDPWMLKFQP 298
>OBSCN_HUMAN (Q5VST9) Obscurin (Obscurin-myosin light chain kinase)| (Obscurin-MLCK) (Obscurin-RhoGEF) Length = 7968 Score = 51.6 bits (122), Expect = 2e-06 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 2/88 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILS--VQYSIPDYVHISSECRDLIAK 492 ++W+ GV Y+ L + PF + R T+ +L V +S P H+S + +D I Sbjct: 6645 DIWAMGVISYLSLTCSSPFAGESD----RATLLNVLEGRVSWSSPMAAHLSEDAKDFIKA 6700 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPAD 408 P R + + +HPWFLK++PA+ Sbjct: 6701 TLQRAPQARPSAAQCLSHPWFLKSMPAE 6728
>MELK_HUMAN (Q14680) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (hMELK) (Protein kinase PK38) (hPK38) Length = 651 Score = 51.6 bits (122), Expect = 2e-06 Identities = 31/123 (25%), Positives = 62/123 (50%), Gaps = 10/123 (8%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G+ LYV++ G PF+D N ++I+ +Y +P ++ SS L+ ++ Sbjct: 191 DVWSMGILLYVLMCGFLPFDD----DNVMALYKKIMRGKYDVPKWLSPSSIL--LLQQML 244 Query: 485 VGNPATRITIPEIRNHPWFLK--NLPADL--------VDDSTMSSQYEEPEQPMQSMDEI 336 +P RI++ + NHPW ++ N P + +DD ++ Q+M+++ Sbjct: 245 QVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDL 304 Query: 335 MQI 327 + + Sbjct: 305 ISL 307
>AURKB_HUMAN (Q96GD4) Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-| and Ipl1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (Aurora-related kinase 2) (STK-1) (Aurora-B) Length = 344 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/82 (30%), Positives = 43/82 (52%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W GV Y +LVG PFE + +R+ ++ L S+P + +DLI+K+ Sbjct: 255 DLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVP------TGAQDLISKLL 308 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 NP+ R+ + ++ HPW N Sbjct: 309 RHNPSERLPLAQVSAHPWVRAN 330
>CDPK4_PLAYO (Q7RJG2) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/78 (32%), Positives = 40/78 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY++L G PF +E +K + +P + IS + +DLI K+ Sbjct: 251 DIWSCGVILYILLSGCPPFNGSNEYDILKKV--ETGKYTFDLPQFKKISDKAKDLIKKML 308 Query: 485 VGNPATRITIPEIRNHPW 432 + A RI+ + H W Sbjct: 309 MYTSAVRISARDALEHEW 326
>CDPK4_PLAF7 (Q8IBS5) Calcium-dependent protein kinase 4 (EC 2.7.11.1)| Length = 527 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/78 (32%), Positives = 40/78 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY++L G PF +E +K + +P + IS + +DLI K+ Sbjct: 251 DIWSCGVILYILLSGCPPFNGSNEYDILKKV--EAGKYTFDLPQFKKISDKAKDLIKKML 308 Query: 485 VGNPATRITIPEIRNHPW 432 + A RI+ + H W Sbjct: 309 MYTSAVRISARDALEHEW 326
>CDPK4_PLABA (P62345) Calcium-dependent protein kinase 4 (EC 2.7.11.1) (PbCDPK4)| Length = 527 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/78 (32%), Positives = 40/78 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WSCGV LY++L G PF +E +K + +P + IS + +DLI K+ Sbjct: 251 DIWSCGVILYILLSGCPPFNGSNEYDILKKV--ETGKYTFDLPQFKKISDKAKDLIKKML 308 Query: 485 VGNPATRITIPEIRNHPW 432 + A RI+ + H W Sbjct: 309 MYTSAVRISARDALEHEW 326
>MAPK2_MOUSE (P49138) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 386 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 2/117 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPD--EPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAK 492 ++WS GV +Y++L G PF KT R+ ++ P++ +S E + LI Sbjct: 231 DMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRN 290 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILA 321 + P R+TI E NHPW +++ T E+ E+ +E+ LA Sbjct: 291 LLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALA 347
>MAPK2_HUMAN (P49137) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2) Length = 400 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 2/117 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPD--EPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAK 492 ++WS GV +Y++L G PF KT R+ ++ P++ +S E + LI Sbjct: 245 DMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRN 304 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILA 321 + P R+TI E NHPW +++ T E+ E+ +E+ LA Sbjct: 305 LLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALA 361
>CAKI_DROME (Q24210) Calcium/calmodulin-dependent protein kinase (EC 2.7.11.17)| (CAKI) (Peripheral plasma membrane protein CaMGUK) Length = 898 Score = 51.2 bits (121), Expect = 3e-06 Identities = 25/78 (32%), Positives = 44/78 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW GV L+V+L G PF ++++ R + + P++ IS+ +DL+ K+ Sbjct: 203 DVWGAGVMLHVLLSGRLPFLGSGV--RLQQSVARG-RLSFEAPEWKSISANAKDLVMKML 259 Query: 485 VGNPATRITIPEIRNHPW 432 NP R++I E+ +HPW Sbjct: 260 AANPHHRLSITEVLDHPW 277
>YP150_YEAST (Q12152) Putative serine/threonine-protein kinase YPL150W (EC| 2.7.11.1) Length = 901 Score = 51.2 bits (121), Expect = 3e-06 Identities = 26/78 (33%), Positives = 42/78 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY ++ G PF+D DE K K + +Y D I + RDLI+++ Sbjct: 214 DIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNE--EPKY---DAKVIPDDARDLISRLL 268 Query: 485 VGNPATRITIPEIRNHPW 432 NP R ++ ++ HP+ Sbjct: 269 AKNPGERPSLSQVLRHPF 286
>MAPK2_CRILO (P49136) MAP kinase-activated protein kinase 2 (EC 2.7.11.1)| (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (P45-54 HSP27 kinase) (Fragment) Length = 329 Score = 51.2 bits (121), Expect = 3e-06 Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 2/117 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPD--EPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAK 492 ++WS GV +Y++L G PF KT R+ ++ P++ +S E + LI Sbjct: 174 DMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRN 233 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILA 321 + P R+TI E NHPW +++ T E+ E+ +E+ LA Sbjct: 234 LLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALA 290
>TSSK6_MOUSE (Q925K9) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 51.2 bits (121), Expect = 3e-06 Identities = 26/78 (33%), Positives = 43/78 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYVM+ G PF+D D R+ + +L PD + +S C+ LIA++ Sbjct: 194 DVWSLGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVL-----YPDGLELSERCKSLIAELL 248 Query: 485 VGNPATRITIPEIRNHPW 432 +P+ R + ++ + W Sbjct: 249 QFSPSARPSAGQVARNGW 266
>KPSH1_PINFU (Q4KTY1) Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1)| Length = 415 Score = 51.2 bits (121), Expect = 3e-06 Identities = 22/82 (26%), Positives = 46/82 (56%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ GV Y++L G PF+D ++ + +R ++ S Y+ + +S++ +D I K+ Sbjct: 258 DMWAVGVITYILLSGTMPFDDENKTRLYRLILKAKYS--YAGEHWKDVSAQAKDFIDKLL 315 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 V +P R++ + H W + N Sbjct: 316 VVSPGDRLSAADALKHQWLISN 337
>KPCD_RAT (P09215) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 673 Score = 50.8 bits (120), Expect = 4e-06 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 2/79 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVH-ISSECRDLIAKIFV 483 WS GV LY ML+G PF DE + F S++ P Y I+ E +D++ K+F Sbjct: 530 WSFGVLLYEMLIGQSPFHGDDEDELFE-------SIRVDTPHYPRWITKESKDIMEKLFE 582 Query: 482 GNPATRITIP-EIRNHPWF 429 +PA R+ + IR HP+F Sbjct: 583 RDPAKRLGVTGNIRLHPFF 601
>ST17A_HUMAN (Q9UEE5) Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP| kinase-related apoptosis-inducing protein kinase 1) Length = 414 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/82 (32%), Positives = 40/82 (48%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV YVML G PF D+ + F Q +++ YS ++ +S D I + Sbjct: 245 DMWSIGVLTYVMLTGISPFLGNDKQETFLNISQ--MNLSYSEEEFDVLSESAVDFIRTLL 302 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 V P R T E HPW ++ Sbjct: 303 VKKPEDRATAEECLKHPWLTQS 324
>CHK1_RAT (Q91ZN7) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/83 (34%), Positives = 43/83 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCG+ L ML G P+ D+P + + + + + I S L+ KI Sbjct: 190 DVWSCGIVLTAMLAGELPW---DQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 485 VGNPATRITIPEIRNHPWFLKNL 417 V NP+ RITIP+I+ W+ K L Sbjct: 247 VENPSARITIPDIKKDRWYNKPL 269
>CHK1_HUMAN (O14757) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/83 (34%), Positives = 43/83 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCG+ L ML G P+ D+P + + + + + I S L+ KI Sbjct: 190 DVWSCGIVLTAMLAGELPW---DQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 485 VGNPATRITIPEIRNHPWFLKNL 417 V NP+ RITIP+I+ W+ K L Sbjct: 247 VENPSARITIPDIKKDRWYNKPL 269
>MAPK5_MOUSE (O54992) MAP kinase-activated protein kinase 5 (EC 2.7.11.1)| (MAPK-activated protein kinase 5) (MAPKAP kinase 5) Length = 473 Score = 50.8 bits (120), Expect = 4e-06 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDE----PKNFRKTIQRILSVQYSIPDYVHISSECRDLI 498 ++WS GV +YVML G PF PK+ RK I S ++ ++ IS +D++ Sbjct: 223 DLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRKKIMTG-SFEFPEEEWSQISEMAKDVV 281 Query: 497 AKIFVGNPATRITIPEIRNHPW 432 K+ P R+TI + +HPW Sbjct: 282 RKLLKVKPEERLTIEGVLDHPW 303
>MAPK3_MOUSE (Q3UMW7) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 50.8 bits (120), Expect = 4e-06 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 2/85 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIAK 492 ++WS GV +Y++L G PF +RI QYS P +++ +S + + LI Sbjct: 226 DMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRL 285 Query: 491 IFVGNPATRITIPEIRNHPWFLKNL 417 + +P R+TI + NHPW +++ Sbjct: 286 LLKTDPTERLTIMQFMNHPWINQSM 310
>KAPA_YEAST (P06244) cAMP-dependent protein kinase type 1 (EC 2.7.11.11) (PKA| 1) (CDC25-suppressing protein kinase) (PK-25) Length = 397 Score = 50.8 bits (120), Expect = 4e-06 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 5/106 (4%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS G+ +Y ML G PF D N KT ++IL+ + P + + + +DL++++ Sbjct: 266 WSFGILIYEMLAGYTPFYD----SNTMKTYEKILNAELRFPPF--FNEDVKDLLSRLITR 319 Query: 479 NPATRIT-----IPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP 357 + + R+ +++NHPWF ++V + +S E P +P Sbjct: 320 DLSQRLGNLQNGTEDVKNHPWF-----KEVVWEKLLSRNIETPYEP 360
>CDPK2_PLAF7 (Q8ICR0) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 508 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV +Y +L G PF + + +K + + D+ ISS+ ++LI K+ Sbjct: 249 DIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYEN--DWGSISSDAKNLITKLL 306 Query: 485 VGNPATRITIPEIRNHPW 432 NP R TI E NHPW Sbjct: 307 TYNPNERCTIEEALNHPW 324
>CDPK2_PLAFK (O15865) Calcium-dependent protein kinase 2 (EC 2.7.11.1) (PfCDPK2)| Length = 512 Score = 50.8 bits (120), Expect = 4e-06 Identities = 27/78 (34%), Positives = 41/78 (52%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV +Y +L G PF + + +K + + D+ ISS+ ++LI K+ Sbjct: 249 DIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYEN--DWGSISSDAKNLITKLL 306 Query: 485 VGNPATRITIPEIRNHPW 432 NP R TI E NHPW Sbjct: 307 TYNPNERCTIEEALNHPW 324
>PLK3_MOUSE (Q60806) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) Length = 631 Score = 50.4 bits (119), Expect = 5e-06 Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G +Y +L G+ PFE D ++T + I V Y++P +S R L+A I Sbjct: 243 DVWSLGCVMYTLLCGSPPFETAD----LKETYRCIKQVHYTLP--ASLSLPARQLLAAIL 296 Query: 485 VGNPATRITIPEIRNHPWFLKNLPAD-LVDDSTMSSQYEEPEQPMQSM 345 +P R +I +I H +F K D L S ++ P P +S+ Sbjct: 297 RASPRDRPSIEQILRHDFFTKGYTPDRLPVSSCVTVPDLTPPNPARSL 344
>PLK1_RAT (Q62673) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) Length = 603 Score = 50.4 bits (119), Expect = 5e-06 Identities = 34/88 (38%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G +Y +LVG PF E ++T RI +YSIP HI+ LI K+ Sbjct: 233 DVWSIGCIMYTLLVGKPPF----ETSCLKETYLRIKKNEYSIPK--HINPVAASLIQKML 286 Query: 485 VGNPATRITIPEIRNHPWFLKN-LPADL 405 +PA R TI E+ N +F +PA L Sbjct: 287 QTDPAARPTIHELLNDEFFTSGYIPARL 314
>MKNK1_XENTR (Q66JF3) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 417 Score = 50.4 bits (119), Expect = 5e-06 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 13/97 (13%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDP-------DEPKNFR----KTIQRILSVQYSIP--DYVH 525 ++WS GV LY+ML G PF D + R K + I +Y P D+ H Sbjct: 230 DLWSLGVILYIMLSGYPPFVGNCGADCGWDRGEMCRVCQNKLFESIQEGKYEFPEKDWSH 289 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFLKNLP 414 IS+ +DLI+K+ V + R++ ++ HPW + P Sbjct: 290 ISNSAKDLISKLLVRDAKERLSAAQVLQHPWLQGDAP 326
>KPCT_HUMAN (Q04759) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 706 Score = 50.4 bits (119), Expect = 5e-06 Identities = 30/79 (37%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVH-ISSECRDLIAKIFV 483 WS GV LY ML+G PF DE + F S++ P Y + E +DL+ K+FV Sbjct: 563 WSFGVLLYEMLIGQSPFHGQDEEELFH-------SIRMDNPFYPRWLEKEAKDLLVKLFV 615 Query: 482 GNPATRITI-PEIRNHPWF 429 P R+ + +IR HP F Sbjct: 616 REPEKRLGVRGDIRQHPLF 634
>TRIB3_RAT (Q9WTQ6) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) Length = 349 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/114 (28%), Positives = 52/114 (45%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 R +VWS GV L+ ML G YPF+D + F K I +++P+ + S+ C LI Sbjct: 235 RAADVWSLGVALFTMLAGRYPFQDSEPALLFGK----IRRGTFALPEGLSASARC--LIR 288 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIM 333 + P+ R+ I HPW ++ SQ P + MD+++ Sbjct: 289 CLLRREPSERLVALGILLHPWLRED-----------CSQVSPPRSDRREMDQVV 331
>PLK3_HUMAN (Q9H4B4) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Proliferation-related kinase) Length = 646 Score = 50.4 bits (119), Expect = 5e-06 Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G +Y +L G+ PFE D ++T + I V Y++P +S R L+A I Sbjct: 242 DVWSLGCVMYTLLCGSPPFETAD----LKETYRCIKQVHYTLP--ASLSLPARQLLAAIL 295 Query: 485 VGNPATRITIPEIRNHPWFLKNLPAD-LVDDSTMSSQYEEPEQPMQSM 345 +P R +I +I H +F K D L S ++ P P +S+ Sbjct: 296 RASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVPDLTPPNPARSL 343
>PLK3_RAT (Q9R011) Serine/threonine-protein kinase PLK3 (EC 2.7.11.21)| (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Fragment) Length = 615 Score = 50.4 bits (119), Expect = 5e-06 Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G +Y +L G+ PFE D ++T + I V Y++P +S R L+A I Sbjct: 211 DVWSLGCVMYTLLCGSPPFETAD----LKETYRCIKQVHYTLP--ASLSLPARQLLAAIL 264 Query: 485 VGNPATRITIPEIRNHPWFLKNLPAD-LVDDSTMSSQYEEPEQPMQSM 345 +P R +I +I H +F K D L S ++ P P +S+ Sbjct: 265 RASPRDRPSIEQILRHDFFTKGYTPDRLPVSSCVTVPDLTPPNPARSL 312
>MELK_MOUSE (Q61846) Maternal embryonic leucine zipper kinase (EC 2.7.11.1)| (Protein kinase PK38) (mPK38) Length = 643 Score = 50.1 bits (118), Expect = 6e-06 Identities = 25/82 (30%), Positives = 47/82 (57%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G+ LYV++ G PF+D N ++I+ +Y +P ++ SS L+ ++ Sbjct: 191 DVWSMGILLYVLMCGFLPFDD----DNVMALYKKIMRGKYEVPKWLSPSSIL--LLQQML 244 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 +P RI++ + NHPW +++ Sbjct: 245 QVDPKKRISMRNLLNHPWVMQD 266
>KPSH1_HUMAN (P11801) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 50.1 bits (118), Expect = 6e-06 Identities = 23/78 (29%), Positives = 43/78 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ GV Y++L G PFED + + +R+ ++ S YS + +S+ +D I ++ Sbjct: 278 DMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS--YSGEPWPSVSNLAKDFIDRLL 335 Query: 485 VGNPATRITIPEIRNHPW 432 +P R+T + HPW Sbjct: 336 TVDPGARMTALQALRHPW 353
>KCC4_HUMAN (Q16566) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 473 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 2/126 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAK 492 ++WS G+ Y++L G PF D + + +RIL+ +Y P + +S +DL+ K Sbjct: 223 DMWSVGIITYILLCGFEPFYDE---RGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRK 279 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEAT 312 + V +P R+T + HPW + A+ V T + +E + + ++A + Sbjct: 280 LIVLDPKKRLTTFQALQHPW-VTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSR 338 Query: 311 IPAAGS 294 + +A S Sbjct: 339 LGSASS 344
>CHK2_MOUSE (Q9Z265) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1)| Length = 546 Score = 50.1 bits (118), Expect = 6e-06 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYS-IPD-YVHISSECRDL 501 R + WS GV L++ L G PF + + + +I S +Y+ IP+ + +S E DL Sbjct: 410 RAVDCWSLGVILFICLSGYPPFSEHKTQVSLK---DQITSGKYNFIPEVWTDVSEEALDL 466 Query: 500 IAKIFVGNPATRITIPEIRNHPW 432 + K+ V +P R+T E NHPW Sbjct: 467 VKKLLVVDPKARLTTEEALNHPW 489
>MKNK2_XENTR (Q66I46) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 466 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/97 (32%), Positives = 46/97 (47%), Gaps = 13/97 (13%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFE---------DPDE--PKNFRKTIQRILSVQYSIP--DYVH 525 ++WS GV LY+ML G PF D E P I +Y P D+ H Sbjct: 276 DLWSLGVILYIMLSGYPPFVGHCGSDCGWDRGEACPACQNMLFVSIQEGKYEFPEKDWAH 335 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFLKNLP 414 ISS +DLI+K+ + + R++ ++ HPW N P Sbjct: 336 ISSGAKDLISKLLLRDAKKRLSAAQVLQHPWVQGNAP 372
>PIM3_XENLA (Q91822) Serine/threonine-protein kinase Pim-3 (EC 2.7.11.1)| (Pim-1) Length = 323 Score = 50.1 bits (118), Expect = 6e-06 Identities = 30/84 (35%), Positives = 39/84 (46%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIA 495 R VWS GV LY M+ G PFE +E R +R IS+EC+ LI Sbjct: 222 RSATVWSLGVLLYDMVYGDIPFEQDEEIVRVRLCFRR------------RISTECQQLIK 269 Query: 494 KIFVGNPATRITIPEIRNHPWFLK 423 P+ R T+ +I +HPW K Sbjct: 270 WCLSLRPSDRPTLEQIFDHPWMCK 293
>KCC4_RAT (P13234) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) (Calspermin) Length = 474 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 2/126 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAK 492 ++WS G+ Y++L G PF D + + +RIL+ +Y P + +S +DL+ K Sbjct: 219 DMWSVGIITYILLCGFEPFYDE---RGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKK 275 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEAT 312 + V +P R+T + HPW + A+ V T + +E + + ++A + Sbjct: 276 LIVLDPKKRLTTFQALQHPW-VTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSR 334 Query: 311 IPAAGS 294 + +A S Sbjct: 335 LGSASS 340
>KCC4_MOUSE (P08414) Calcium/calmodulin-dependent protein kinase type IV (EC| 2.7.11.17) (CAM kinase-GR) (CaMK IV) Length = 469 Score = 50.1 bits (118), Expect = 6e-06 Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 2/126 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAK 492 ++WS G+ Y++L G PF D + + +RIL+ +Y P + +S +DL+ K Sbjct: 219 DMWSVGIITYILLCGFEPFYDE---RGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKK 275 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAEAT 312 + V +P R+T + HPW + A+ V T + +E + + ++A + Sbjct: 276 LIVLDPKKRLTTFQALQHPW-VTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSR 334 Query: 311 IPAAGS 294 + +A S Sbjct: 335 LGSASS 340
>KS6A2_MOUSE (Q9WUT3) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase-activated protein kinase 1c) (M Length = 733 Score = 50.1 bits (118), Expect = 6e-06 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 3/83 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIA 495 +VWS G+ LY ML G PF + PD+ + + RI S +Y++ ++ IS +D+++ Sbjct: 593 DVWSLGILLYTMLAGFTPFANGPDDTPE--EILARIGSGKYALSGGNWDSISDAAKDVVS 650 Query: 494 KIFVGNPATRITIPEIRNHPWFL 426 K+ +P R+T ++ HPW + Sbjct: 651 KMLHVDPQQRLTAVQVLKHPWIV 673 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/83 (31%), Positives = 46/83 (55%), Gaps = 5/83 (6%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G+ PF+ D ++T+ IL + +P + +S+E + L+ +F Sbjct: 243 WSFGVLMFEMLTGSLPFQGKDR----KETMALILKAKLGMPQF--LSAEAQSLLRALFKR 296 Query: 479 NPATRI-----TIPEIRNHPWFL 426 NP R+ + EI+ HP+F+ Sbjct: 297 NPCNRLGAGVDGVEEIKRHPFFV 319
>KCC1A_RAT (Q63450) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAKIF 486 WS GV Y++L G PF D ++ K F ++IL +Y P + IS +D I + Sbjct: 202 WSIGVIAYILLCGYPPFYDENDAKLF----EQILKAEYEFDSPYWDDISDSAKDFIRHLM 257 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEE 369 +P R T + HPW + D ++S Q ++ Sbjct: 258 EKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKK 296
>KCC1A_MOUSE (Q91YS8) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 374 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAKIF 486 WS GV Y++L G PF D ++ K F ++IL +Y P + IS +D I + Sbjct: 202 WSIGVIAYILLCGYPPFYDENDAKLF----EQILKAEYEFDSPYWDDISDSAKDFIRHLM 257 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEE 369 +P R T + HPW + D ++S Q ++ Sbjct: 258 EKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKK 296
>KCC1A_HUMAN (Q14012) Calcium/calmodulin-dependent protein kinase type 1 (EC| 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) Length = 370 Score = 49.7 bits (117), Expect = 8e-06 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAKIF 486 WS GV Y++L G PF D ++ K F ++IL +Y P + IS +D I + Sbjct: 202 WSIGVIAYILLCGYPPFYDENDAKLF----EQILKAEYEFDSPYWDDISDSAKDFIRHLM 257 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEE 369 +P R T + HPW + D ++S Q ++ Sbjct: 258 EKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKK 296
>AURKC_MOUSE (O88445) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 1) (Aurora-C) Length = 282 Score = 49.7 bits (117), Expect = 8e-06 Identities = 25/78 (32%), Positives = 42/78 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W GV Y +LVG PFE + +R RI V + P V ++ DLI+K+ Sbjct: 194 DLWCIGVLCYELLVGKPPFESSTSSETYR----RIRQVDFKFPSSVPAGAQ--DLISKLL 247 Query: 485 VGNPATRITIPEIRNHPW 432 +P+ R+++ ++ HPW Sbjct: 248 RYHPSERLSLAQVLKHPW 265
>UNC89_CAEEL (O01761) Muscle M-line assembly protein unc-89 (Uncoordinated protein| 89) Length = 8081 Score = 49.3 bits (116), Expect = 1e-05 Identities = 23/78 (29%), Positives = 40/78 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV YV+L G PF ++ +T+ + S Q+ + S + D + K+ Sbjct: 6804 DMWSTGVLTYVLLTGLSPFHGDND----NETLANVDSCQFDSSPLGNFSYDAGDFVKKLL 6859 Query: 485 VGNPATRITIPEIRNHPW 432 P +R+T+ E +HPW Sbjct: 6860 TEIPVSRLTVDEALDHPW 6877 Score = 30.8 bits (68), Expect = 4.0 Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPF-EDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKI 489 ++W GV + +L G +PF + D + ++ + + IP V+ S EC Sbjct: 7958 DMWGMGVVTFCLLAGFHPFTSEYDREEEIKENVINVKCDPNLIP--VNASQECLSFATWA 8015 Query: 488 FVGNPATRITIPEIRNHPWFLKNLPA 411 +P R+ E +H FL + P+ Sbjct: 8016 LKKSPVRRMRTDEALSHK-FLSSDPS 8040
>MAPK3_HUMAN (Q16644) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) (Chromosome 3p kinase) (3pK) Length = 382 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 2/117 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIAK 492 ++WS GV +Y++L G PF +RI QY P ++ +S + + LI Sbjct: 224 DMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRL 283 Query: 491 IFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILA 321 + +P R+TI + NHPW +++ T E+ + + +E+ LA Sbjct: 284 LLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSALA 340
>KS6A1_RAT (Q63531) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 49.3 bits (116), Expect = 1e-05 Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLI 498 ++WS GV LY ML G PF + D P+ + RI S ++++ ++ +S +DL+ Sbjct: 596 DIWSLGVLLYTMLAGYTPFANGPSDTPEEI---LTRISSGKFTLSGGNWNTVSETAKDLV 652 Query: 497 AKIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQ 378 +K+ +P R+T ++ HPW + D + S +S Q Sbjct: 653 SKMLHVDPHQRLTAKQVLQHPWITQK---DKLPQSQLSHQ 689 Score = 43.5 bits (101), Expect = 6e-04 Identities = 22/66 (33%), Positives = 38/66 (57%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G+ PF+ D ++T+ IL + +P + +S+E + L+ +F Sbjct: 246 WSYGVLMFEMLTGSLPFQGKDR----KETMTLILKAKLGMPQF--LSTEAQSLLRALFKR 299 Query: 479 NPATRI 462 NPA R+ Sbjct: 300 NPANRL 305
>CHK1_XENLA (Q6DE87) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (xChk1| protein) Length = 474 Score = 49.3 bits (116), Expect = 1e-05 Identities = 26/80 (32%), Positives = 44/80 (55%), Gaps = 1/80 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEP-KNFRKTIQRILSVQYSIPDYVHISSECRDLIAKI 489 +VWSCG+ L ML G P++ P+E + + ++ + + + IS+ L+ K+ Sbjct: 190 DVWSCGIVLTAMLAGELPWDQPNEVCQEYCDWKEK----NHYLTPWKKISATPLALLCKM 245 Query: 488 FVGNPATRITIPEIRNHPWF 429 NP +RITIP+I+ WF Sbjct: 246 LTENPQSRITIPDIKKDRWF 265
>DAPK1_HUMAN (P53355) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1432 Score = 49.3 bits (116), Expect = 1e-05 Identities = 25/80 (31%), Positives = 44/80 (55%), Gaps = 2/80 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPD--YVHISSECRDLIAK 492 ++WS GV Y++L GA PF + ++T+ + +V Y D + + S+ +D I + Sbjct: 199 DMWSIGVITYILLSGASPFLGDTK----QETLANVSAVNYEFEDEYFSNTSALAKDFIRR 254 Query: 491 IFVGNPATRITIPEIRNHPW 432 + V +P R+TI + HPW Sbjct: 255 LLVKDPKKRMTIQDSLQHPW 274
>KS6A2_HUMAN (Q15349) Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1)| (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C) Length = 733 Score = 48.9 bits (115), Expect = 1e-05 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 3/81 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIA 495 ++WS G+ LY ML G PF + PD+ + + RI S +Y++ ++ IS +D+++ Sbjct: 593 DIWSLGILLYTMLAGFTPFANGPDDTPE--EILARIGSGKYALSGGNWDSISDAAKDVVS 650 Query: 494 KIFVGNPATRITIPEIRNHPW 432 K+ +P R+T ++ HPW Sbjct: 651 KMLHVDPHQRLTAMQVLKHPW 671 Score = 48.5 bits (114), Expect = 2e-05 Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 5/83 (6%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G+ PF+ D ++T+ IL + +P + +S E + L+ +F Sbjct: 243 WSFGVLMFEMLTGSLPFQGKDR----KETMALILKAKLGMPQF--LSGEAQSLLRALFKR 296 Query: 479 NPATRI-----TIPEIRNHPWFL 426 NP R+ + EI+ HP+F+ Sbjct: 297 NPCNRLGAGIDGVEEIKRHPFFV 319
>KPCT_MOUSE (Q02111) Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)| Length = 707 Score = 48.9 bits (115), Expect = 1e-05 Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVH-ISSECRDLIAKIFV 483 WS GV +Y ML+G PF DE + F S++ P Y + E +DL+ K+FV Sbjct: 563 WSFGVLVYEMLIGQSPFHGQDEEELFH-------SIRMDNPFYPRWLEREAKDLLVKLFV 615 Query: 482 GNPATRITI-PEIRNHPWF 429 P R+ + +IR HP F Sbjct: 616 REPEKRLGVRGDIRQHPLF 634
>PHKG2_RAT (P31325) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/79 (31%), Positives = 44/79 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV L+ +L G+ PF + R ++ Q+S P++ S+ +DLIAK+ Sbjct: 215 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEG--QYQFSSPEWDDRSNTVKDLIAKLL 272 Query: 485 VGNPATRITIPEIRNHPWF 429 +P R+T + HP+F Sbjct: 273 QVDPNARLTAEQALQHPFF 291
>MAPK3_RAT (Q66H84) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIAK 492 ++WS GV +Y++L G PF +RI QY P ++ +S + + LI Sbjct: 226 DMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPKPEWADVSEDAKQLIRL 285 Query: 491 IFVGNPATRITIPEIRNHPWFLKNL 417 + +P R+TI + NHPW +++ Sbjct: 286 LLKTDPTERLTIMQFMNHPWINQSM 310
>MAPK3_BOVIN (Q3SYZ2) MAP kinase-activated protein kinase 3 (EC 2.7.11.1)| (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAPK-3) Length = 384 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 2/85 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLIAK 492 ++WS GV +Y++L G PF +RI QY P ++ +S + + LI Sbjct: 226 DMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPSPEWSEVSEDAKQLIRL 285 Query: 491 IFVGNPATRITIPEIRNHPWFLKNL 417 + +P R+TI + NHPW +++ Sbjct: 286 LLKTDPTERLTITQFMNHPWINQSM 310
>CDPK1_ORYSA (P53682) Calcium-dependent protein kinase, isoform 1 (EC 2.7.11.1)| (CDPK 1) Length = 534 Score = 48.9 bits (115), Expect = 1e-05 Identities = 24/82 (29%), Positives = 39/82 (47%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ GV LYV+L G PF + + K + + + + IS +DLI K+ Sbjct: 255 DIWTAGVILYVLLTGVPPFWADTQSGIYEKVLDG--RIDFKSNRWPRISDSAKDLIKKML 312 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 P+ R+ E+ HPW N Sbjct: 313 CPYPSERLKAHEVLKHPWICDN 334
>CDPK3_ORYSA (P53684) Calcium-dependent protein kinase, isoform 11 (EC 2.7.11.1)| (CDPK 11) Length = 542 Score = 48.9 bits (115), Expect = 1e-05 Identities = 31/117 (26%), Positives = 56/117 (47%), Gaps = 1/117 (0%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYV+L G PF + F ++ + + + IS +DLI K+ Sbjct: 261 DVWSAGVILYVLLSGVPPFWAETQQGIFDAVLKG--HIDFQSDPWPKISDSAKDLIRKML 318 Query: 485 VGNPATRITIPEIRNHPWFLKN-LPADLVDDSTMSSQYEEPEQPMQSMDEIMQILAE 318 P+ R+ E+ HPW +N + D D ++ S+ ++ + ++++AE Sbjct: 319 SHCPSERLKAHEVLRHPWICENGVATDQALDPSVISRLKQFSAMNKLKKLALRVIAE 375
>PLK1_MOUSE (Q07832) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 1/88 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G +Y +LVG PF E ++T RI +YSIP HI+ LI K+ Sbjct: 233 DVWSIGCIMYTLLVGKPPF----ETSCLKETYLRIKKNEYSIPK--HINPVAASLIQKML 286 Query: 485 VGNPATRITIPEIRNHPWFLKN-LPADL 405 +P R TI E+ N +F +PA L Sbjct: 287 QTDPTARPTIHELLNDEFFTSGYIPARL 314
>PLK1_HUMAN (P53350) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) Length = 603 Score = 48.9 bits (115), Expect = 1e-05 Identities = 33/88 (37%), Positives = 45/88 (51%), Gaps = 1/88 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS G +Y +LVG PF E ++T RI +YSIP HI+ LI K+ Sbjct: 233 DVWSIGCIMYTLLVGKPPF----ETSCLKETYLRIKKNEYSIPK--HINPVAASLIQKML 286 Query: 485 VGNPATRITIPEIRNHPWFLKN-LPADL 405 +P R TI E+ N +F +PA L Sbjct: 287 QTDPTARPTINELLNDEFFTSGYIPARL 314
>KS6B2_HUMAN (Q9UBS0) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2)| (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serin Length = 482 Score = 48.5 bits (114), Expect = 2e-05 Identities = 32/116 (27%), Positives = 61/116 (52%), Gaps = 6/116 (5%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS G +Y ML G+ PF +N +KT+ +I+ + ++P Y ++ + RDL+ K Sbjct: 253 WSLGALMYDMLTGSPPF----TAENRKKTMDKIIRGKLALPPY--LTPDARDLVKKFLKR 306 Query: 479 NPATRI-----TIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP-MQSMDEIMQ 330 NP+ RI +++ HP+F + D ++ + + P +P +QS +++ Q Sbjct: 307 NPSQRIGGGPGDAADVQRHPFF-----RHMNWDDLLAWRVDPPFRPCLQSEEDVSQ 357
>CHK1_MOUSE (O35280) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/83 (33%), Positives = 42/83 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWSCG+ L ML G P+ D+P + + + + + I S L+ KI Sbjct: 190 DVWSCGIVLTAMLAGELPW---DQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKIL 246 Query: 485 VGNPATRITIPEIRNHPWFLKNL 417 V P+ RITIP+I+ W+ K L Sbjct: 247 VETPSARITIPDIKKDRWYNKPL 269
>CHK1_CHICK (Q8AYC9) Serine/threonine-protein kinase Chk1 (EC 2.7.11.1)| Length = 476 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDP-DEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKI 489 +VW+CGV L ML G P++ P D + + +R + + + I S L+ KI Sbjct: 190 DVWACGVVLTAMLAGELPWDQPSDSCQEYSDWKER----KTYLAPWRKIDSAPLALLHKI 245 Query: 488 FVGNPATRITIPEIRNHPWFLKNL 417 NP RITIP+I+ W+ + L Sbjct: 246 LTENPTARITIPDIKKDRWYCRPL 269
>KAPC_YEAST (P05986) cAMP-dependent protein kinase type 3 (EC 2.7.11.11) (PKA| 3) Length = 398 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 5/106 (4%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV +Y ML G PF + N KT + IL+ + P + H + +DL+ K+ Sbjct: 267 WSFGVLIYEMLAGYTPFYN----SNTMKTYENILNAELKFPPFFH--PDAQDLLKKLITR 320 Query: 479 NPATRIT-----IPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP 357 + + R+ +++NHPWF +++ + ++ E P +P Sbjct: 321 DLSERLGNLQNGSEDVKNHPWF-----NEVIWEKLLARYIETPYEP 361
>TSSK6_HUMAN (Q9BXA6) Testis-specific serine/threonine-protein kinase 6 (EC| 2.7.11.1) (TSSK-6) (Small serine/threonine kinase) (Serine/threonine-protein kinase SSTK) Length = 273 Score = 48.5 bits (114), Expect = 2e-05 Identities = 25/78 (32%), Positives = 43/78 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV LYVM+ G PF+D D R+ + +L P+ + +S C+ LIA++ Sbjct: 194 DVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVL-----YPEGLELSERCKALIAELL 248 Query: 485 VGNPATRITIPEIRNHPW 432 +P+ R + ++ + W Sbjct: 249 QFSPSARPSAGQVARNCW 266
>TRIB3_HUMAN (Q96RU7) Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible| putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK) Length = 358 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/78 (37%), Positives = 40/78 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV L+ ML G YPF+D + F K I Y++P +S+ R L+ + Sbjct: 243 DVWSLGVALFTMLAGHYPFQDSEPVLLFGK----IRRGAYALP--AGLSAPARCLVRCLL 296 Query: 485 VGNPATRITIPEIRNHPW 432 PA R+T I HPW Sbjct: 297 RREPAERLTATGILLHPW 314
>CRK_DAUCA (P53681) CDPK-related protein kinase (EC 2.7.11.1) (PK421)| Length = 602 Score = 48.5 bits (114), Expect = 2e-05 Identities = 27/82 (32%), Positives = 44/82 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV Y++L G+ PF E FR ++ LS + P + +SSE +D + ++ Sbjct: 334 DVWSIGVISYILLCGSRPFWARTESGIFRAVLKANLS--FDEPPWPSVSSEAKDFVKRLL 391 Query: 485 VGNPATRITIPEIRNHPWFLKN 420 +P R+T + H W +KN Sbjct: 392 NKDPRKRMTAAQALCHSW-IKN 412
>KPCD_MOUSE (P28867) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 674 Score = 48.5 bits (114), Expect = 2e-05 Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVH-ISSECRDLIAKIFV 483 WS GV LY ML+G PF DE + F S++ P Y I+ E +D++ K+F Sbjct: 530 WSFGVLLYEMLIGQSPFHGDDEDELFE-------SIRVDTPHYPRWITKESKDIMEKLFE 582 Query: 482 GNPATRITIP-EIRNHPWF 429 +P R+ + IR HP+F Sbjct: 583 RDPDKRLGVTGNIRIHPFF 601
>PIM1_BOVIN (Q9N0P9) Proto-oncogene serine/threonine-protein kinase pim-1 (EC| 2.7.11.1) Length = 313 Score = 48.1 bits (113), Expect = 2e-05 Identities = 28/77 (36%), Positives = 37/77 (48%) Frame = -2 Query: 662 VWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFV 483 VWS G+ LY M+ G PFE +E V+ + +SSEC+ LI Sbjct: 225 VWSLGILLYDMVCGDIPFEHDEE------------IVRGQVFFRQRVSSECQHLIRWCLA 272 Query: 482 GNPATRITIPEIRNHPW 432 P+ R T EI+NHPW Sbjct: 273 LRPSDRPTFEEIQNHPW 289
>KCC1D_MOUSE (Q8BW96) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) (mCKLiK) Length = 385 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAKIF 486 WS GV Y++L G PF D ++ K F ++IL +Y P + IS +D I + Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLF----EQILKAEYEFDSPYWDDISDSAKDFIRNLM 260 Query: 485 VGNPATRITIPEIRNHPW 432 +P R T + HPW Sbjct: 261 EKDPNKRYTCEQAARHPW 278
>KCC1D_HUMAN (Q8IU85) Calcium/calmodulin-dependent protein kinase type 1D (EC| 2.7.11.17) (CaM kinase ID) (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI delta) (Camk1D) (CamKI-like protein kinase) (CKLiK) Length = 385 Score = 48.1 bits (113), Expect = 2e-05 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI--PDYVHISSECRDLIAKIF 486 WS GV Y++L G PF D ++ K F ++IL +Y P + IS +D I + Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLF----EQILKAEYEFDSPYWDDISDSAKDFIRNLM 260 Query: 485 VGNPATRITIPEIRNHPW 432 +P R T + HPW Sbjct: 261 EKDPNKRYTCEQAARHPW 278
>PHKG2_HUMAN (P15735) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) (PSK-C3) Length = 406 Score = 48.1 bits (113), Expect = 2e-05 Identities = 24/79 (30%), Positives = 44/79 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV L+ +L G+ PF + R ++ Q+S P++ SS +DLI+++ Sbjct: 215 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEG--QYQFSSPEWDDRSSTVKDLISRLL 272 Query: 485 VGNPATRITIPEIRNHPWF 429 +P R+T + HP+F Sbjct: 273 QVDPEARLTAEQALQHPFF 291
>YPK1_YEAST (P12688) Serine/threonine-protein kinase YPK1 (EC 2.7.11.1)| Length = 680 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 W+ GV LY ML G P+ D D PK ++K +Q L PD + +DL+ + Sbjct: 529 WTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLV----FPD--GFDRDAKDLLIGLLSR 582 Query: 479 NPATRITI---PEIRNHPWF 429 +P R+ EIRNHP+F Sbjct: 583 DPTRRLGYNGADEIRNHPFF 602
>KS6A1_MOUSE (P18653) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 724 Score = 48.1 bits (113), Expect = 2e-05 Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLI 498 ++WS G+ LY ML G PF + D P+ + RI S ++++ ++ +S +DL+ Sbjct: 585 DIWSLGILLYTMLAGYTPFANGPSDTPEEI---LTRIGSGKFTLSGGNWNTVSETAKDLV 641 Query: 497 AKIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQ 378 +K+ +P R+T ++ HPW + D + S +S Q Sbjct: 642 SKMLHVDPHQRLTAKQVLQHPWITQK---DKLPQSQLSHQ 678
>PIM1_HUMAN (P11309) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 404 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/77 (35%), Positives = 37/77 (48%) Frame = -2 Query: 662 VWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFV 483 VWS G+ LY M+ G PFE +E ++ + +SSEC+ LI Sbjct: 316 VWSLGILLYDMVCGDIPFEHDEE------------IIRGQVFFRQRVSSECQHLIRWCLA 363 Query: 482 GNPATRITIPEIRNHPW 432 P+ R T EI+NHPW Sbjct: 364 LRPSDRPTFEEIQNHPW 380
>KS6B2_MOUSE (Q9Z1M4) Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta| 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2) Length = 485 Score = 47.8 bits (112), Expect = 3e-05 Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 6/122 (4%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS G +Y ML G+ PF +N +KT+ +I+ + +P Y ++ + RDL K Sbjct: 253 WSLGALMYDMLTGSPPF----TAENRKKTMDKIIKGKLVLPPY--LTPDARDLAKKFLKR 306 Query: 479 NPATRI-----TIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP-MQSMDEIMQILAE 318 NP RI +++ HP+F + D ++ + + P +P +QS +++ Q A Sbjct: 307 NPTQRIGGGLGDAADVQRHPFF-----RHINWDDLLARRVDPPFRPSLQSEEDVSQFDAR 361 Query: 317 AT 312 T Sbjct: 362 FT 363
>KPSH1_MOUSE (Q91YA2) Serine/threonine-protein kinase H1 (EC 2.7.11.1) (PSK-H1)| Length = 423 Score = 47.8 bits (112), Expect = 3e-05 Identities = 22/78 (28%), Positives = 42/78 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ GV Y++L G PFED + + +R+ ++ S Y + +S+ +D I ++ Sbjct: 278 DMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYS--YLGEPWPSVSNLAKDFIDRLL 335 Query: 485 VGNPATRITIPEIRNHPW 432 +P R+T + HPW Sbjct: 336 TVDPGARMTALQALRHPW 353
>MKNK1_XENLA (Q9YGW0) MAP kinase-interacting serine/threonine-protein kinase 1| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (Mnk1) Length = 418 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 13/97 (13%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDP-------DEPKNFR----KTIQRILSVQYSIP--DYVH 525 ++WS GV LY+ML G PF D + R K + I +Y P D+ H Sbjct: 230 DLWSLGVILYIMLSGYPPFVGNCGTDCGWDRGEVCRVCQNKLFESIQEGKYEFPEKDWSH 289 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFLKNLP 414 IS +DLI+K+ V + R++ ++ HPW + P Sbjct: 290 ISISAKDLISKLLVRDAKERLSAFQVLQHPWLQGDAP 326
>PLK2_HUMAN (Q9NYY3) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 685 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/91 (28%), Positives = 47/91 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ G +Y ML+G PF E N ++T + I +Y++P + + + LIA + Sbjct: 262 DIWALGCVMYTMLLGRPPF----ETTNLKETYRCIREARYTMPS--SLLAPAKHLIASML 315 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDS 393 NP R ++ +I H +FL+ D + S Sbjct: 316 SKNPEDRPSLDDIIRHDFFLQGFTPDRLSSS 346
>PKH1_YEAST (Q03407) Serine/threonine-protein kinase PKH1 (EC 2.7.11.1)| (3-phosphoinositide-dependent protein kinase 1) Length = 766 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 6/130 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ G LY ML G PF+ +E T Q+++ +QY+ +DL+ K+ Sbjct: 319 DIWAFGCILYQMLAGKPPFKAANE----YLTFQKVMKIQYAFT--AGFPQIVKDLVKKLL 372 Query: 485 VGNPATRITIPEIRNHPWF--LKNLPADLVDDSTMSSQ----YEEPEQPMQSMDEIMQIL 324 V +P R+TI +I+ H +F + + DD+ Q E +P+Q + E + Sbjct: 373 VRDPNDRLTIKQIKAHLFFHEVNFEDGSVWDDNPPEIQPYKINAEAMKPLQKVSESDTTV 432 Query: 323 AEATIPAAGS 294 A + AG+ Sbjct: 433 KMANLQLAGN 442
>PHKG2_MOUSE (Q9DB30) Phosphorylase b kinase gamma catalytic chain, testis/liver| isoform (EC 2.7.11.19) (PHK-gamma-T) (Phosphorylase kinase gamma subunit 2) Length = 406 Score = 47.8 bits (112), Expect = 3e-05 Identities = 23/79 (29%), Positives = 44/79 (55%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+CGV L+ +L G+ PF + R ++ Q++ P++ S+ +DLI+K+ Sbjct: 215 DLWACGVILFTLLAGSPPFWHRRQILMLRMIMEG--QYQFTSPEWDDCSNTVKDLISKLL 272 Query: 485 VGNPATRITIPEIRNHPWF 429 +P R+T + HP+F Sbjct: 273 QVDPEARLTAEQALQHPFF 291
>PLK2_RAT (Q9R012) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/91 (28%), Positives = 47/91 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ G +Y ML+G PF E N ++T + I +Y++P + + + LIA + Sbjct: 259 DIWALGCVMYTMLLGRPPF----ETTNLKETYRCIREARYTMPS--SLLAPAKHLIASML 312 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDS 393 NP R ++ +I H +FL+ D + S Sbjct: 313 SKNPEDRPSLDDIIRHDFFLQGFTPDRLSSS 343
>PLK2_MOUSE (P53351) Serine/threonine-protein kinase PLK2 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Length = 682 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/91 (28%), Positives = 47/91 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W+ G +Y ML+G PF E N ++T + I +Y++P + + + LIA + Sbjct: 259 DIWALGCVMYTMLLGRPPF----ETTNLKETYRCIREARYTMPS--SLLAPAKHLIASML 312 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDS 393 NP R ++ +I H +FL+ D + S Sbjct: 313 SKNPEDRPSLDDIIRHDFFLQGFTPDRLSSS 343
>PIM1_BRARE (Q9YHZ5) Serine/threonine-protein kinase Pim-1 (EC 2.7.11.1)| Length = 310 Score = 47.8 bits (112), Expect = 3e-05 Identities = 25/81 (30%), Positives = 38/81 (46%) Frame = -2 Query: 662 VWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFV 483 VWS GV LY M+ G PFE + + + + IS++CR LI Sbjct: 225 VWSLGVLLYDMVCGDIPFEQDTDIVKAKPSFNK------------RISNDCRSLICSCLS 272 Query: 482 GNPATRITIPEIRNHPWFLKN 420 NP R ++ +I HPW +++ Sbjct: 273 YNPGDRPSLEQILQHPWMMES 293
>KS6A1_HUMAN (Q15418) Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1)| (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A) Length = 735 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/100 (29%), Positives = 53/100 (53%), Gaps = 4/100 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLI 498 ++WS G+ LY ML G PF + D P+ + RI S ++++ ++ +S +DL+ Sbjct: 596 DIWSLGILLYTMLAGYTPFANGPSDTPEEI---LTRIGSGKFTLSGGNWNTVSETAKDLV 652 Query: 497 AKIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQ 378 +K+ +P R+T ++ HPW + D + S +S Q Sbjct: 653 SKMLHVDPHQRLTAKQVLQHPWVTQK---DKLPQSQLSHQ 689 Score = 43.9 bits (102), Expect = 5e-04 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 5/82 (6%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G+ PF+ D ++T+ IL + +P + +S+E + L+ +F Sbjct: 246 WSYGVLMFEMLTGSLPFQGKDR----KETMTLILKAKLGMPQF--LSTEAQSLLRALFKR 299 Query: 479 NPATRI-----TIPEIRNHPWF 429 NPA R+ EI+ H ++ Sbjct: 300 NPANRLGSGPDGAEEIKRHVFY 321
>PLK1_XENLA (P70032) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/79 (35%), Positives = 42/79 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS G +Y +LVG PF E ++T RI +YSIP HI+ LI K+ Sbjct: 224 DIWSIGCIMYTLLVGKPPF----ETSCLKETYMRIKKNEYSIPK--HINPVAAALIQKML 277 Query: 485 VGNPATRITIPEIRNHPWF 429 +P +R TI ++ N +F Sbjct: 278 RSDPTSRPTIDDLLNDEFF 296
>PIM1_MOUSE (P06803) Proto-oncogene serine/threonine-protein kinase Pim-1 (EC| 2.7.11.1) Length = 397 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Frame = -2 Query: 662 VWSCGVTLYVMLVGAYPFEDPDEPKN----FRKTIQRILSVQYSIPDYVHISSECRDLIA 495 VWS G+ LY M+ G PFE +E FR+T+ SSEC+ LI Sbjct: 309 VWSLGILLYDMVCGDIPFEHDEEIIKGQVFFRQTV----------------SSECQHLIK 352 Query: 494 KIFVGNPATRITIPEIRNHPWFLKNL 417 P+ R + EIRNHPW +L Sbjct: 353 WCLSLRPSDRPSFEEIRNHPWMQGDL 378
>KS6AA_CHICK (P18652) Ribosomal protein S6 kinase 2 alpha (EC 2.7.11.1)| (Ribosomal protein S6 kinase II alpha) (S6KII-alpha) (P90-RSK) (MAP kinase-activated protein kinase 1) (MAPK-activated protein kinase 1) (MAPKAP kinase 1) (MAPKAPK-1) Length = 752 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 4/82 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLI 498 ++WS GV LY ML G PF + D P+ + RI ++S+ ++ IS +DL+ Sbjct: 613 DIWSLGVLLYTMLAGCTPFANGPSDTPEEI---LTRIGGGKFSVNGGNWDTISDVAKDLV 669 Query: 497 AKIFVGNPATRITIPEIRNHPW 432 +K+ +P R+T ++ HPW Sbjct: 670 SKMLHVDPHQRLTAKQVLQHPW 691 Score = 47.4 bits (111), Expect = 4e-05 Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 5/82 (6%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G+ PF+ D ++T+ IL + +P + +S+E + L+ +F Sbjct: 264 WSYGVLMFEMLTGSLPFQGKDR----KETMTLILKAKLGMPQF--LSAEAQSLLRALFKR 317 Query: 479 NPATRI-----TIPEIRNHPWF 429 NPA R+ EI+ HP++ Sbjct: 318 NPANRLGSGPDGAEEIKRHPFY 339
>MKNK2_XENLA (Q6P431) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 467 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 13/97 (13%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFE---------DPDE--PKNFRKTIQRILSVQYSIP--DYVH 525 ++WS GV LY+ML G PF D E P I +Y P D+ H Sbjct: 276 DLWSLGVILYIMLSGYPPFVGHCGSDCGWDRGEACPACQNMLFVSIQEGKYEFPEKDWAH 335 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPWFLKNLP 414 IS +DLI+K+ + + R++ ++ HPW N P Sbjct: 336 ISYGAKDLISKLLLRDAKKRLSAAQVLQHPWVQGNAP 372
>KS6A3_MOUSE (P18654) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B) Length = 740 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 3/83 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTIQRILSVQYSIPD--YVHISSECRDLIA 495 ++WS GV LY ML G PF + PD+ + + RI S ++S+ + +S +DL++ Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDDTPE--EILARIGSGKFSLSGGYWNSVSDTAKDLVS 657 Query: 494 KIFVGNPATRITIPEIRNHPWFL 426 K+ +P R+T + HPW + Sbjct: 658 KMLHVDPHQRLTAALVLRHPWIV 680 Score = 46.2 bits (108), Expect = 9e-05 Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G PF+ D ++T+ IL + +P + +S E + L+ +F Sbjct: 252 WSFGVLMFEMLTGTLPFQGKDR----KETMTMILKAKLGMPQF--LSPEAQSLLRMLFKR 305 Query: 479 NPATRI-----TIPEIRNHPWF 429 NPA R+ + EI+ H +F Sbjct: 306 NPANRLGAGPDGVEEIKRHSFF 327
>KS6A3_HUMAN (P51812) Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1)| (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protei Length = 740 Score = 47.8 bits (112), Expect = 3e-05 Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 3/83 (3%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED-PDEPKNFRKTIQRILSVQYSIPD--YVHISSECRDLIA 495 ++WS GV LY ML G PF + PD+ + + RI S ++S+ + +S +DL++ Sbjct: 600 DIWSLGVLLYTMLTGYTPFANGPDDTPE--EILARIGSGKFSLSGGYWNSVSDTAKDLVS 657 Query: 494 KIFVGNPATRITIPEIRNHPWFL 426 K+ +P R+T + HPW + Sbjct: 658 KMLHVDPHQRLTAALVLRHPWIV 680 Score = 46.2 bits (108), Expect = 9e-05 Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G PF+ D ++T+ IL + +P + +S E + L+ +F Sbjct: 252 WSFGVLMFEMLTGTLPFQGKDR----KETMTMILKAKLGMPQF--LSPEAQSLLRMLFKR 305 Query: 479 NPATRI-----TIPEIRNHPWF 429 NPA R+ + EI+ H +F Sbjct: 306 NPANRLGAGPDGVEEIKRHSFF 327
>CDS1_SCHPO (Q09170) Serine/threonine-protein kinase cds1 (EC 2.7.11.1)| (Checkpoint kinase cds1) Length = 460 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVH--ISSECRDLIAK 492 ++WS G LYVML + PF + K I+ I Y I + IS E DLI + Sbjct: 357 DIWSLGCVLYVMLTASIPFASSSQAK----CIELISKGAYPIEPLLENEISEEGIDLINR 412 Query: 491 IFVGNPATRITIPEIRNHPWF 429 + NP RI+ E HPWF Sbjct: 413 MLEINPEKRISESEALQHPWF 433
>CDC5_YEAST (P32562) Cell cycle serine/threonine-protein kinase CDC5/MSD2 (EC| 2.7.11.21) Length = 705 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/96 (31%), Positives = 48/96 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS GV LY +L+G PF + ++ +RI +S P IS E + LI I Sbjct: 263 DIWSLGVMLYALLIGKPPF----QARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDIL 318 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQ 378 +P R ++ EI ++ WF P + ST+ S+ Sbjct: 319 SLDPIERPSLTEIMDYVWFRGTFPPSI--PSTVMSE 352
>DAPK2_MOUSE (Q8VDF3) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 47.4 bits (111), Expect = 4e-05 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 2/80 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPD--YVHISSECRDLIAK 492 ++WS GV Y++L GA PF + ++T+ I +V Y + + S +D I K Sbjct: 209 DMWSIGVITYILLSGASPFLGDTK----QETLANITAVSYDFDEEFFSQTSELAKDFIRK 264 Query: 491 IFVGNPATRITIPEIRNHPW 432 + V R+TI E HPW Sbjct: 265 LLVKETRKRLTIQEALRHPW 284
>DAPK2_HUMAN (Q9UIK4) Death-associated protein kinase 2 (EC 2.7.11.1) (DAP| kinase 2) (DAP-kinase-related protein 1) (DRP-1) Length = 370 Score = 47.4 bits (111), Expect = 4e-05 Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 2/80 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPD--YVHISSECRDLIAK 492 ++WS GV Y++L GA PF + ++T+ I +V Y + + S +D I K Sbjct: 209 DMWSIGVITYILLSGASPFLGDTK----QETLANITAVSYDFDEEFFSQTSELAKDFIRK 264 Query: 491 IFVGNPATRITIPEIRNHPW 432 + V R+TI E HPW Sbjct: 265 LLVKETRKRLTIQEALRHPW 284
>KIN2_YEAST (P13186) Serine/threonine-protein kinase KIN2 (EC 2.7.11.1)| Length = 1147 Score = 47.4 bits (111), Expect = 4e-05 Identities = 24/78 (30%), Positives = 41/78 (52%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS G+ LYV++ G PF+D +N ++I + P H+S E L+ ++ Sbjct: 305 DIWSFGIVLYVLVCGKVPFDD----ENSSILHEKIKKGKVDYPS--HLSIEVISLLTRMI 358 Query: 485 VGNPATRITIPEIRNHPW 432 V +P R T+ + HPW Sbjct: 359 VVDPLRRATLKNVVEHPW 376
>KPCD_HUMAN (Q05655) Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta)| Length = 676 Score = 47.4 bits (111), Expect = 4e-05 Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVH-ISSECRDLIAKIFV 483 WS GV LY ML+G PF DE + F S++ P Y I+ E +D++ K+F Sbjct: 532 WSFGVLLYEMLIGQSPFHGDDEDELFE-------SIRVDTPHYPRWITKESKDILEKLFE 584 Query: 482 GNPATRITIP-EIRNHPWF 429 P R+ + I+ HP+F Sbjct: 585 REPTKRLGMTGNIKIHPFF 603
>MKNK2_HUMAN (Q9HBH9) MAP kinase-interacting serine/threonine-protein kinase 2| (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (Mnk2) Length = 465 Score = 47.4 bits (111), Expect = 4e-05 Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 13/91 (14%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFE---------DPDE--PKNFRKTIQRILSVQYSIPD--YVH 525 ++WS GV LY++L G PF D E P + I +Y PD + H Sbjct: 277 DLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESIQEGKYEFPDKDWAH 336 Query: 524 ISSECRDLIAKIFVGNPATRITIPEIRNHPW 432 IS +DLI+K+ V + R++ ++ HPW Sbjct: 337 ISCAAKDLISKLLVRDAKQRLSAAQVLQHPW 367
>DAPK1_MOUSE (Q80YE7) Death-associated protein kinase 1 (EC 2.7.11.1) (DAP| kinase 1) Length = 1442 Score = 47.4 bits (111), Expect = 4e-05 Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 2/80 (2%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPD--YVHISSECRDLIAK 492 ++WS GV Y++L GA PF + ++T+ + +V Y + + + S+ +D I + Sbjct: 199 DMWSIGVITYILLSGASPFLGDTK----QETLANVSAVNYDFEEEFFRNTSTLAKDFIRR 254 Query: 491 IFVGNPATRITIPEIRNHPW 432 + V +P R+TI + HPW Sbjct: 255 LLVKDPKKRMTIQDSLQHPW 274
>KS6A6_HUMAN (Q9UK32) Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1)| (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4) Length = 745 Score = 47.0 bits (110), Expect = 5e-05 Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 3/104 (2%) Frame = -2 Query: 659 WSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIFVG 480 WS GV ++ ML G PF+ D +T+ IL + +P + +S+E + L+ +F Sbjct: 257 WSYGVLMFEMLTGTLPFQGKDR----NETMNMILKAKLGMPQF--LSAEAQSLLRMLFKR 310 Query: 479 NPATRI---TIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQP 357 NPA R+ + EI+ H +F A++ D + + P +P Sbjct: 311 NPANRLGSEGVEEIKRHLFF-----ANIDWDKLYKREVQPPFKP 349 Score = 39.7 bits (91), Expect = 0.009 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 4/82 (4%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFED--PDEPKNFRKTIQRILSVQYSIP--DYVHISSECRDLI 498 ++WS GV Y ML G PF + D P+ + + RI + ++S+ ++ +IS +DL+ Sbjct: 604 DIWSLGVLFYTMLAGYTPFANGPNDTPE---EILLRIGNGKFSLSGGNWDNISDGAKDLL 660 Query: 497 AKIFVGNPATRITIPEIRNHPW 432 + + +P R T +I H W Sbjct: 661 SHMLHMDPHQRYTAEQILKHSW 682
>CHK2_HUMAN (O96017) Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1)| Length = 543 Score = 47.0 bits (110), Expect = 5e-05 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 2/121 (1%) Frame = -2 Query: 674 RLRNVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYS-IPD-YVHISSECRDL 501 R + WS GV L++ L G PF + + + +I S +Y+ IP+ + +S + DL Sbjct: 406 RAVDCWSLGVILFICLSGYPPFSEHRTQVSLK---DQITSGKYNFIPEVWAEVSEKALDL 462 Query: 500 IAKIFVGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEEPEQPMQSMDEIMQILA 321 + K+ V +P R T E HPW + D M ++++ + Q+LA Sbjct: 463 VKKLLVVDPKARFTTEEALRHPW---------LQDEDMKRKFQDLLSEENESTALPQVLA 513 Query: 320 E 318 + Sbjct: 514 Q 514
>PLK1_XENTR (P62205) Serine/threonine-protein kinase PLK1 (EC 2.7.11.21)| (Polo-like kinase 1) (PLK-1) (Plx1) Length = 598 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/79 (34%), Positives = 41/79 (51%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++WS G +Y +LVG PF E ++T RI +YS+P HI+ LI K+ Sbjct: 224 DIWSIGCIMYTLLVGKPPF----ETSCLKETYMRIKKNEYSVPK--HINPMATALIQKML 277 Query: 485 VGNPATRITIPEIRNHPWF 429 P +R TI ++ N +F Sbjct: 278 RSEPTSRPTIDDLLNDEFF 296
>KIN1_YEAST (P13185) Protein kinase KIN1 (EC 2.7.11.1)| Length = 1064 Score = 47.0 bits (110), Expect = 5e-05 Identities = 26/81 (32%), Positives = 43/81 (53%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VWS GV L+V++ G PF+D + K Q V+Y H+S E L++K+ Sbjct: 326 DVWSFGVVLFVLVCGKVPFDDENSSVLHEKIKQG--KVEYP----QHLSIEVISLLSKML 379 Query: 485 VGNPATRITIPEIRNHPWFLK 423 V +P R T+ ++ H W ++ Sbjct: 380 VVDPKRRATLKQVVEHHWMVR 400
>KCC1B_RAT (O70150) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 47.0 bits (110), Expect = 5e-05 Identities = 26/99 (26%), Positives = 47/99 (47%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GV Y++L G PF D +P+ F + ++ S ++ P + IS +D I + Sbjct: 194 DVWALGVISYILLCGYPPFYDESDPELFSQILR--ASYEFDSPFWDDISESAKDFIRHLL 251 Query: 485 VGNPATRITIPEIRNHPWFLKNLPADLVDDSTMSSQYEE 369 +P R T + H W + D ++S Q ++ Sbjct: 252 ERDPQKRFTCQQALQHLWISGDAALDRDILGSVSEQIQK 290
>AURKC_HUMAN (Q9UQB9) Serine/threonine-protein kinase 13 (EC 2.7.11.1)| (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C) Length = 309 Score = 47.0 bits (110), Expect = 5e-05 Identities = 26/78 (33%), Positives = 39/78 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 ++W GV Y +LVG PFE + +R RIL V P + + RDLI+++ Sbjct: 221 DLWCIGVLCYELLVGYPPFESASHSETYR----RILKVDVRFP--LSMPLGARDLISRLL 274 Query: 485 VGNPATRITIPEIRNHPW 432 P R+ + +I HPW Sbjct: 275 RYQPLERLPLAQILKHPW 292
>KCC1B_MOUSE (Q9QYK9) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 46.6 bits (109), Expect = 7e-05 Identities = 23/78 (29%), Positives = 39/78 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GV Y++L G PF D +P+ F + ++ S ++ P + IS +D I + Sbjct: 194 DVWALGVISYILLCGYPPFYDESDPELFSQILR--ASYEFDSPFWDDISESAKDFIRHLL 251 Query: 485 VGNPATRITIPEIRNHPW 432 +P R T + H W Sbjct: 252 ERDPQKRFTCQQALQHLW 269
>KCC1B_HUMAN (Q6P2M8) Calcium/calmodulin-dependent protein kinase type 1B (EC| 2.7.11.17) (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase) Length = 343 Score = 46.6 bits (109), Expect = 7e-05 Identities = 23/78 (29%), Positives = 39/78 (50%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYVHISSECRDLIAKIF 486 +VW+ GV Y++L G PF D +P+ F + ++ S ++ P + IS +D I + Sbjct: 194 DVWALGVISYILLCGYPPFYDESDPELFSQILR--ASYEFDSPFWDDISESAKDFIRHLL 251 Query: 485 VGNPATRITIPEIRNHPW 432 +P R T + H W Sbjct: 252 ERDPQKRFTCQQALRHLW 269
>KOK0_YEAST (Q12236) Probable serine/threonine-protein kinase YOL100W (EC| 2.7.11.1) Length = 1081 Score = 46.6 bits (109), Expect = 7e-05 Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSI-PDYVHISSECRDLIAKI 489 ++W+ G L+ M+ G PF+ +E F Q+++ VQY+ P + I RDL+ KI Sbjct: 371 DIWAFGCILFQMIAGKPPFKATNEYLTF----QKVMKVQYAFTPGFPLI---IRDLVKKI 423 Query: 488 FVGNPATRITIPEIRNHPWF 429 V N R+TI +I+ H +F Sbjct: 424 LVKNLDRRLTISQIKEHHFF 443
>LIN2_CAEEL (P54936) Protein lin-2 (Abnormal cell lineage protein 2)| Length = 961 Score = 46.6 bits (109), Expect = 7e-05 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Frame = -2 Query: 665 NVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILSVQYSIPDYV-HISSECRDLIAKI 489 ++WS GV L+++L G PF + +RI+ + Y+ +IS R+L+ ++ Sbjct: 207 DIWSSGVVLFLLLAGRLPFSG-----STSDIYERIMQTDVDVDGYMPNISESARNLVRRM 261 Query: 488 FVGNPATRITIPEIRNHPW 432 +P+ RI+ E NH W Sbjct: 262 LNADPSKRISAKEALNHEW 280 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,118,117 Number of Sequences: 219361 Number of extensions: 1536845 Number of successful extensions: 6138 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 5597 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5856 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6655306086 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
