ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbaal4g19 |
|---|---|
| Clone Library Name | barley_pub |
>DHGY_CUCSA (P13443) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) Length = 382 Score = 251 bits (641), Expect = 1e-66 Identities = 119/145 (82%), Positives = 131/145 (90%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 EADVISLHPVLDKTT+HL+N E L MKK+A+L+N SRGPVIDE ALV+HL+ NPMFRVG Sbjct: 236 EADVISLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVG 295 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 LDVFEDEPYMKPGLA+MKNA++VPHIASASKWTREGMATLAALNVLGKIKGYPVW +PN Sbjct: 296 LDVFEDEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNR 355 Query: 273 VEPFLDEEATPPPACPSIVNAKQLG 199 VEPFLDE +PP A PSIVNAK LG Sbjct: 356 VEPFLDENVSPPAASPSIVNAKALG 380
>GYAR_THELI (Q9C4M5) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 331 Score = 107 bits (267), Expect = 3e-23 Identities = 55/111 (49%), Positives = 72/111 (64%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D ISLH L K TYH+I + L +MK A+L+N SRG V+D AL++ LK + G Sbjct: 204 ESDFISLHVPLTKETYHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAG 263 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDVFE+EPY L ++KN V+ PHI SA+ REGMA L A N++ KG Sbjct: 264 LDVFEEEPYYNEELFKLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKG 314
>GYAR_PYRHO (O58320) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 334 Score = 103 bits (257), Expect = 4e-22 Identities = 55/111 (49%), Positives = 72/111 (64%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D + L L + TYHLIN ERL +MKK A+L+N +RG V+D ALV+ LK + G Sbjct: 204 ESDFVVLAVPLTRETYHLINEERLKLMKKTAILINIARGKVVDTNALVKALKEGWIAGAG 263 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDVFE+EPY L ++ N V+ PHI SAS REGMA L A N++ +G Sbjct: 264 LDVFEEEPYYNEELFKLDNVVLTPHIGSASFGAREGMAELVAKNLIAFKRG 314
>GYAR_PYRAB (Q9UYR1) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 102 bits (254), Expect = 9e-22 Identities = 53/111 (47%), Positives = 72/111 (64%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D + L L+K TYH+IN ERL MMK+ A+L+N +RG VID AL++ LK + G Sbjct: 205 ESDFVVLAVPLNKETYHMINEERLKMMKRTAILINVARGKVIDTKALIKALKEGWIAGAG 264 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDV+E+EPY L + N V+ PHI SA+ REGMA L A N++ +G Sbjct: 265 LDVYEEEPYYNEELFSLDNVVLTPHIGSATFGAREGMAKLVAENLIAFKRG 315
>GYAR_PYRKO (Q5JEZ2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 333 Score = 97.4 bits (241), Expect = 3e-20 Identities = 51/106 (48%), Positives = 69/106 (65%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D + L L K T ++IN ERL +MKK A+LVN +RG V+D AL++ LK + G Sbjct: 204 ESDFVVLAVPLTKETQYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAG 263 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVL 316 LDV+E+EPY L +KN V+ PHI SA+ REGMA L A N++ Sbjct: 264 LDVYEEEPYYNEELFSLKNVVLAPHIGSATYGAREGMAELVARNLI 309
>GYAR_PYRFU (Q8U3Y2) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 336 Score = 92.4 bits (228), Expect = 1e-18 Identities = 50/111 (45%), Positives = 68/111 (61%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D + L L K T ++IN ERL +MK A+LVN +RG V+D AL++ LK + G Sbjct: 204 ESDFVILAVPLTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAG 263 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDVFE+EPY L + N V+ PHI SA+ RE MA L A N++ +G Sbjct: 264 LDVFEEEPYYNEELFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRG 314
>TKRA_ENTAG (P58000) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 323 Score = 89.7 bits (221), Expect = 6e-18 Identities = 49/112 (43%), Positives = 68/112 (60%), Gaps = 1/112 (0%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D + + L + T+H+I E+LA MK A+L+NA RGPV+DE AL+ LK + G Sbjct: 199 ESDFLCISLPLTEQTHHMIGREQLAKMKPSAILINAGRGPVVDEQALIAALKDKTIHAAG 258 Query: 453 LDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDVFE EP + L + N V +PHI SA+ TR GMA A N++ + G Sbjct: 259 LDVFEQEPLPVDSELLTLPNVVALPHIGSATHETRYGMARDAVDNLIAALAG 310
>TKRA_ECOLI (P37666) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 89.4 bits (220), Expect = 8e-18 Identities = 49/112 (43%), Positives = 65/112 (58%), Gaps = 1/112 (0%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ L+ + G Sbjct: 200 ESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAG 259 Query: 453 LDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDVFE EP + L M N V VPHI SA+ TR GMA A N++ ++G Sbjct: 260 LDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQG 311
>TKRA_ECO57 (P58220) 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| (2-ketoaldonate reductase) Length = 324 Score = 89.4 bits (220), Expect = 8e-18 Identities = 49/112 (43%), Positives = 65/112 (58%), Gaps = 1/112 (0%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D + L L T+HL E+ A MK A+ +NA RGPV+DE AL+ L+ + G Sbjct: 200 ESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAG 259 Query: 453 LDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDVFE EP + L M N V VPHI SA+ TR GMA A N++ ++G Sbjct: 260 LDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQG 311
>GYAR_AERPE (Q9YAW4) Glyoxylate reductase (EC 1.1.1.26) (Glycolate reductase)| Length = 335 Score = 86.3 bits (212), Expect = 7e-17 Identities = 49/113 (43%), Positives = 69/113 (61%), Gaps = 2/113 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D++S+H L T HLI L +MKK A+LVN RG ++D ALV+ L+ + Sbjct: 205 ESDILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAA 264 Query: 453 LDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDVFE+EP + P L KN V+ PH ASA++ TR MA +AA N++ +G Sbjct: 265 LDVFEEEP-LNPNHPLTAFKNVVLAPHAASATRETRLRMAMMAAENLVAFAQG 316
>YEAA_SCHPO (O14075) Putative 2-hydroxyacid dehydrogenase UNK4.10 (EC 1.-.-.-)| Length = 334 Score = 81.6 bits (200), Expect = 2e-15 Identities = 42/105 (40%), Positives = 64/105 (60%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++DV+SL+ L+ T H+I MK+ V+VN +RG V+DE ALVE L ++ G Sbjct: 209 KSDVLSLNLPLNAHTRHIIGKPEFQKMKRGIVIVNTARGAVMDEAALVEALDEGIVYSAG 268 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 319 LDVFE+EP + PGL E + +++PH+ + S T+ M +NV Sbjct: 269 LDVFEEEPKIHPGLLENEKVILLPHLGTNSLETQYKMECAVLMNV 313
>YN14_YEAST (P53839) Putative 2-hydroxyacid dehydrogenase YNL274C (EC 1.-.-.-)| Length = 350 Score = 79.0 bits (193), Expect = 1e-14 Identities = 47/137 (34%), Positives = 72/137 (52%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D++S++ L+ T+HLIN E + MK V+VN +RG VIDE A+ + L++ + GL Sbjct: 218 SDIVSVNVPLNHNTHHLINAETIEKMKDGVVIVNTARGAVIDEQAMTDALRSGKIRSAGL 277 Query: 450 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 271 DVFE EP + L M + +PH+ + S TR+ M L N K + G + Sbjct: 278 DVFEYEPKISKELLSMSQVLGLPHMGTHSVETRKKMEELVVENA----KNVILTGKVLTI 333 Query: 270 EPFLDEEATPPPACPSI 220 P L E P + P + Sbjct: 334 VPELQNEDWPNESKPLV 350
>SERA_METJA (Q58424) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 524 Score = 78.6 bits (192), Expect = 1e-14 Identities = 41/110 (37%), Positives = 64/110 (58%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD I+LH L T H+I E++A+MKK A++VN +RG +IDE AL E LK + L Sbjct: 195 ADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRAAAL 254 Query: 450 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 DVFE+EP L + N + PH ++++ ++ T+ A + ++G Sbjct: 255 DVFEEEPPKDNPLLTLDNVIGTPHQGASTEEAQKAAGTIVAEQIKKVLRG 304
>SERA_ARATH (O04130) D-3-phosphoglycerate dehydrogenase, chloroplast precursor| (EC 1.1.1.95) (3-PGDH) Length = 624 Score = 78.2 bits (191), Expect = 2e-14 Identities = 58/147 (39%), Positives = 78/147 (53%), Gaps = 3/147 (2%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD +SLH L T + N E + MKK L+N +RG VIDE ALV L A + + L Sbjct: 276 ADFVSLHMPLTPATKKVFNDETFSKMKKGVRLINVARGGVIDEDALVRALDAGIVAQAAL 335 Query: 450 DVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 DVF +EP K L + +N V PH+ +++K +EG+A A V G +KG NA Sbjct: 336 DVFCEEPPSKDSRLIQHENVTVTPHLGASTKEAQEGVAIEIAEAVAGALKGELSATAVNA 395 Query: 273 --VEPFLDEEATPPPACPSIVNAKQLG 199 V P + E T P IV A++LG Sbjct: 396 PMVAPEVLSELT-----PYIVLAEKLG 417
>SERA_METTH (O27051) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 77.8 bits (190), Expect = 2e-14 Identities = 56/148 (37%), Positives = 80/148 (54%), Gaps = 3/148 (2%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D++++H L T HLI+ + +MK A +VN +RG +IDE AL LK + Sbjct: 195 ESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALKDGEIAGAA 254 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHI-ASASKWTREGMATLAALNVLGKIKGYPVWGNPN 277 LDVFE+EP L E++N V+ PHI AS S+ R+ AA+ V +IK G P Sbjct: 255 LDVFEEEPPEGSPLLELENVVLTPHIGASTSEAQRD-----AAIIVANEIKTVFQGGAPR 309 Query: 276 AV--EPFLDEEATPPPACPSIVNAKQLG 199 V P +D E T P I A+++G Sbjct: 310 NVLNMPVMDSE-TYKSLKPYIELAEKMG 336
>SERA_BACSU (P35136) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 525 Score = 75.9 bits (185), Expect = 9e-14 Identities = 47/132 (35%), Positives = 68/132 (51%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD+I++H L K T L+N E +A KK L+N +RG +IDE AL+E L+ + L Sbjct: 193 ADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIIDEAALLEALENGHVAGAAL 252 Query: 450 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 271 DVFE EP + L + + PH+ +++K + +A + VL KG PV N Sbjct: 253 DVFEVEPPVDNKLVDHPLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKGLPVMSAINLP 312 Query: 270 EPFLDEEATPPP 235 DE A P Sbjct: 313 AMTKDEFAKIKP 324
>TKRA_BACSU (O32264) Probable 2-ketogluconate reductase (EC 1.1.1.215) (2KR)| Length = 325 Score = 75.9 bits (185), Expect = 9e-14 Identities = 43/112 (38%), Positives = 61/112 (54%), Gaps = 1/112 (0%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++D I L L TYH+I +MK A+ VN SRG +DE AL+ L+ + G Sbjct: 203 QSDFILLITPLTDETYHMIGEREFKLMKNSAIFVNISRGKTVDEKALIRALQEGWIRGAG 262 Query: 453 LDVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDV+E EP + L ++ N ++PHI SA+ R M AA N+L I+G Sbjct: 263 LDVYEKEPVTQDNPLLQLDNVTLLPHIGSATAKVRFNMCKQAAENMLAAIQG 314
>Y1556_HAEIN (P45250) Putative 2-hydroxyacid dehydrogenase HI1556 (EC 1.-.-.-)| Length = 315 Score = 75.5 bits (184), Expect = 1e-13 Identities = 43/95 (45%), Positives = 56/95 (58%), Gaps = 5/95 (5%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+++LH L +TT LIN E L+ MKK A L+N RGP+IDE+ALV+ LK + Sbjct: 196 QADIVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGHLGGAA 255 Query: 453 LDVFEDEPYMKP-----GLAEMKNAVVVPHIASAS 364 LDV EP K M N ++ PHIA AS Sbjct: 256 LDVMVKEPPEKDNPLILAAKTMPNLIITPHIAWAS 290
>DHGY_METEX (Q59516) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) (HPR-A) Length = 313 Score = 73.6 bits (179), Expect = 5e-13 Identities = 42/116 (36%), Positives = 65/116 (56%), Gaps = 3/116 (2%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++DVI+LH L T ++I E+L MK+ A+L+N +RG ++DE AL++ LK + G Sbjct: 192 QSDVITLHVPLTPDTKNMIGAEQLKKMKRSAILINTARGGLVDEAALLQALKDGTIGGAG 251 Query: 453 LDVFEDEPYMKPGL---AEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 295 DV EP + A++ N +V PH+A ASK + +A NV + G P Sbjct: 252 FDVVAQEPPKDGNILCDADLPNLIVTPHVAWASKEAMQILADQLVDNVEAFVAGKP 307
>SERA_ARCFU (O29445) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 527 Score = 73.6 bits (179), Expect = 5e-13 Identities = 43/125 (34%), Positives = 69/125 (55%), Gaps = 3/125 (2%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +DVI++H K T LI + MK ++VNA+RG ++DE AL E +KA + L Sbjct: 194 SDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVDEAALYEAIKAGKVAAAAL 253 Query: 450 DVFEDEPYMKPG-LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPN- 277 DV+E EP L ++ N V PHIA++++ + + + A +++ KG PV N Sbjct: 254 DVYEKEPPSPDNPLLKLDNVVTTPHIAASTREAQLNVGMIIAEDIVNMAKGLPVRNAVNL 313 Query: 276 -AVEP 265 ++EP Sbjct: 314 PSIEP 318
>SERA_SYNY3 (P73821) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 554 Score = 72.0 bits (175), Expect = 1e-12 Identities = 41/113 (36%), Positives = 61/113 (53%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 EAD I+LH T +LIN E LA MK A ++N SRG +IDE ALV ++ + Sbjct: 221 EADFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETAQIGGAA 280 Query: 453 LDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYP 295 LDVF EP + L E N ++ PH+ ++++ + +A A + + G P Sbjct: 281 LDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLGLP 333
>SERA_MYCLE (O33116) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 68.9 bits (167), Expect = 1e-11 Identities = 44/130 (33%), Positives = 67/130 (51%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD IS+H T LI+ E LA K ++VNA+RG ++DEVAL + +++ + GL Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGL 255 Query: 450 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 271 DVF EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 256 DVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVD 315 Query: 270 EPFLDEEATP 241 ++EE P Sbjct: 316 GGVVNEEVAP 325
>PDXB_PHOLL (Q7N2B2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 68.6 bits (166), Expect = 2e-11 Identities = 42/102 (41%), Positives = 62/102 (60%), Gaps = 4/102 (3%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EAD+++ H L+K+ T+HL++ E L+++ +L+NASRG VID AL+ LK Sbjct: 167 EADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLTALKCGKK 226 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 RV LDV+E EP + L E+ + + PHIA +T EG A Sbjct: 227 LRVVLDVWEPEPDLSLPLLELVD-IGTPHIAG---YTLEGKA 264
>GRHPR_HUMAN (Q9UBQ7) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 68.6 bits (166), Expect = 2e-11 Identities = 42/115 (36%), Positives = 63/115 (54%), Gaps = 1/115 (0%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++D I + L T L N + MK+ AV +N SRG V+++ L + L + + G Sbjct: 208 QSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAG 267 Query: 453 LDVFEDEPY-MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPV 292 LDV EP L +KN V++PHI SA+ TR M+ LAA N+L ++G P+ Sbjct: 268 LDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322
>CTBP2_HUMAN (P56545) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 66.2 bits (160), Expect = 7e-11 Identities = 55/171 (32%), Positives = 82/171 (47%), Gaps = 22/171 (12%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + LK + Sbjct: 235 QSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAA 294 Query: 453 LDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLAALNVLGKI----- 307 LDV E EP + + L + N + PH A AS RE AT + G+I Sbjct: 295 LDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLR 354 Query: 306 ----KGYPVWGNPNAVEPFLDEEATPPPA-------CPSIVNAKQLGLPSS 187 K + V P +V +D++A P P IV GLP++ Sbjct: 355 NCVNKEFFVTSAPWSV---IDQQAIHPELNGATYRYPPGIVGVAPGGLPAA 402
>CTBP2_MOUSE (P56546) C-terminal-binding protein 2 (CtBP2)| Length = 445 Score = 65.9 bits (159), Expect = 1e-10 Identities = 42/115 (36%), Positives = 62/115 (53%), Gaps = 6/115 (5%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++D +SLH L++ +HLIN + M++ A LVNA+RG ++DE AL + LK + Sbjct: 235 QSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAA 294 Query: 453 LDVFEDEP--YMKPGLAEMKNAVVVPHIA----SASKWTREGMATLAALNVLGKI 307 LDV E EP + + L + N + PH A AS RE AT + G+I Sbjct: 295 LDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRI 349
>SERA_MYCTU (P0A544) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/130 (33%), Positives = 64/130 (49%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + GL Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGL 255 Query: 450 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 271 DVF EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 256 DVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVG 315 Query: 270 EPFLDEEATP 241 ++EE P Sbjct: 316 GGVVNEEVAP 325
>SERA_MYCBO (P0A545) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 528 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/130 (33%), Positives = 64/130 (49%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD IS+H T LI+ E LA K ++VNA+RG ++DE AL + + + GL Sbjct: 196 ADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGL 255 Query: 450 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNAV 271 DVF EP L E+ VV PH+ +++ ++ T A +V + G V N Sbjct: 256 DVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVG 315 Query: 270 EPFLDEEATP 241 ++EE P Sbjct: 316 GGVVNEEVAP 325
>PDXB_VIBVY (Q7MIT6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/91 (41%), Positives = 53/91 (58%), Gaps = 4/91 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL L+ Sbjct: 168 EADVITLHTPITRDGKYPTHHLINKEILNSLRADQILINAARGPVVDNQALKHRLQQADG 227 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 373 F LDVFE EP + L + A PH+A Sbjct: 228 FTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_VIBVU (Q8DB36) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/91 (41%), Positives = 53/91 (58%), Gaps = 4/91 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EADVI+LH + + T+HLIN E L ++ + +L+NA+RGPV+D AL L+ Sbjct: 168 EADVITLHTPITRDGKYPTHHLINEEILNSLRADQILINAARGPVVDNQALKRRLQQADG 227 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 373 F LDVFE EP + L + A PH+A Sbjct: 228 FMAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_PSEAE (Q9I3W9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 65.1 bits (157), Expect = 2e-10 Identities = 42/94 (44%), Positives = 53/94 (56%), Gaps = 4/94 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EADVISLH L++ T HL++ RLA ++ LVNASRG V+D AL L+ Sbjct: 167 EADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRLLEGGAD 226 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 V LDV+E EP P LA + + PHIA S Sbjct: 227 LEVALDVWEGEPQADPELA-ARCLIATPHIAGYS 259
>GRHPR_MOUSE (Q91Z53) Glyoxylate reductase/hydroxypyruvate reductase (EC| 1.1.1.79) Length = 328 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/113 (36%), Positives = 62/113 (54%), Gaps = 2/113 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+D I + L T L + + MK A+ +N SRG V+++ L + L + + G Sbjct: 208 ESDFIVVSCSLTPDTMGLCSKDFFQKMKNTAIFINISRGDVVNQEDLYQALASGQIAAAG 267 Query: 453 LDVFEDEPYMKPG--LAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 LDV EP + P L +KN V++PHI SA+ TR M+ LAA N+L ++G Sbjct: 268 LDVTTPEP-LPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRG 319
>SERA_BOVIN (Q5EAD2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 64.3 bits (155), Expect = 3e-10 Identities = 37/118 (31%), Positives = 59/118 (50%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDSTFAQCKKGVCVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 447 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 VF +EP L +N + PH+ +++K + AL + +KG + G NA Sbjct: 260 VFTEEPPRDRALVNHENVISCPHLGASTKEAQSRCGEEIALQFVDMVKGKALAGVVNA 317
>CTBP_DROME (O46036) C-terminal-binding protein (CtBP protein) (dCtBP)| Length = 476 Score = 63.9 bits (154), Expect = 4e-10 Identities = 45/146 (30%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++D +SLH L++ +HLIN + M+ A LVN +RG ++D+ L LK + Sbjct: 229 QSDCVSLHCTLNEHNHHLINEFTIKQMRPGAFLVNTARGGLVDDETLALALKQGRIRAAA 288 Query: 453 LDVFEDEPY--MKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNP 280 LDV E+EPY + L + N + PH A S + + +AA + I G P Sbjct: 289 LDVHENEPYNVFQGALKDAPNLICTPHAAFFSDASATELREMAATEIRRAIVG----NIP 344 Query: 279 NAVEPFLDEE---ATPPPACPSIVNA 211 + + +++E TPP A V A Sbjct: 345 DVLRNCVNKEYFMRTPPAAAAGGVAA 370
>PDXB_PSEPK (Q88L20) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 63.5 bits (153), Expect = 5e-10 Identities = 41/94 (43%), Positives = 54/94 (57%), Gaps = 4/94 (4%) Frame = -2 Query: 633 EADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 + DVISLH L + T+HL+ +LA ++ A LVNASRGPV+D VAL E L Sbjct: 166 QCDVISLHTPLQRGGQHPTWHLLGQAQLAQLRPGAWLVNASRGPVVDNVALRELLLDRED 225 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 LDV+E EP + LA++ + PHIA S Sbjct: 226 VHAVLDVWEGEPQVDLQLADL-CTLATPHIAGYS 258
>YPRB2_CORML (P0C1E9) Hypothetical protein in proB 3'region (EC 1.-.-.-)| Length = 304 Score = 63.5 bits (153), Expect = 5e-10 Identities = 41/106 (38%), Positives = 53/106 (50%), Gaps = 1/106 (0%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 EADV L L TY ++N E L MK AVLVN RGP+I+ LV+ L + Sbjct: 180 EADVFVLILPLTDATYQIVNAETLGKMKPSAVLVNVGRGPLINTDDLVDALNNGTIAGAA 239 Query: 453 LDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 319 LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 240 LDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>SERA_RAT (O08651) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 447 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_MOUSE (Q61753) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| (A10) Length = 532 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 447 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_HUMAN (O43175) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.5 bits (153), Expect = 5e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 447 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_PONPY (Q5R7M2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 447 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRGRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNA 317
>SERA_MACFA (Q60HD7) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (3-PGDH)| Length = 532 Score = 63.2 bits (152), Expect = 6e-10 Identities = 36/118 (30%), Positives = 60/118 (50%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 D I++H L +T L+N A KK +VN +RG ++DE AL+ L++ LD Sbjct: 200 DFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALD 259 Query: 447 VFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNA 274 VF +EP L + +N + PH+ +++K + A+ + +KG + G NA Sbjct: 260 VFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLAGVVNA 317
>PTXD_PSEST (O69054) Phosphonate dehydrogenase (EC 1.20.1.1) (NAD-dependent| phosphite dehydrogenase) Length = 336 Score = 62.8 bits (151), Expect = 8e-10 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 8/118 (6%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D I L L+ T HL+N E LA+++ A+LVN RG V+DE A++ L+ + Sbjct: 201 SDFILLALPLNADTQHLVNAELLALVRPGALLVNPCRGSVVDEAAVLAALERGQLGGYAA 260 Query: 450 DVFEDEPYMK--------PGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 DVFE E + + P L N + PHI SA + R + AA N++ + G Sbjct: 261 DVFEMEDWARADRPRLIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAAQNIIQVLAG 318
>SERA_HAEIN (P43885) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 410 Score = 62.8 bits (151), Expect = 8e-10 Identities = 40/116 (34%), Positives = 62/116 (53%), Gaps = 6/116 (5%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 DV+SLH +T +L+N R+A +K+ A+L+NA+RG V+D AL + LK + +D Sbjct: 206 DVVSLHVPELPSTKNLMNVARIAQLKQGAILINAARGTVVDIDALAQALKDGKLQGAAID 265 Query: 447 VFEDEP------YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 298 VF EP ++ P L E N ++ PHI ++ +E + V GK Y Sbjct: 266 VFPVEPASINEEFISP-LREFDNVILTPHIGGSTAEAQENI----GFEVAGKFVKY 316
>Y2355_CORGL (P0C1E8) Hypothetical protein Cgl2355/cg2587 (EC 1.-.-.-)| Length = 304 Score = 62.4 bits (150), Expect = 1e-09 Identities = 40/106 (37%), Positives = 53/106 (50%), Gaps = 1/106 (0%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 EADV L L TY ++N E L MK AV+VN RGP+I+ LV+ L + Sbjct: 180 EADVFVLILPLTDATYQIVNAETLGKMKPSAVVVNVGRGPLINTDDLVDALNNGTIAGAA 239 Query: 453 LDVFEDEPYM-KPGLAEMKNAVVVPHIASASKWTREGMATLAALNV 319 LDV + EP L EM N V+ PH A+ ++ R L N+ Sbjct: 240 LDVTDPEPLPDSHPLWEMDNVVITPHTANTNERIRALTGELTLRNI 285
>PDXB_VIBCH (Q9KQ92) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 381 Score = 62.0 bits (149), Expect = 1e-09 Identities = 45/129 (34%), Positives = 65/129 (50%), Gaps = 6/129 (4%) Frame = -2 Query: 633 EADVISLHPVLDK----TTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 +ADVI+LH + + T+HLI+ L ++ + +L+NA+RGPV+D AL L+ Sbjct: 168 QADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALKARLQQGDG 227 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA--TLAALNVLGKIKGYPV 292 F LDVFE EP + L + A PHIA + EG A T N + G Sbjct: 228 FTAVLDVFEFEPQVDMELLPLL-AFATPHIAG---YGLEGKARGTTMIFNSYCEFLGSAH 283 Query: 291 WGNPNAVEP 265 NP ++ P Sbjct: 284 CANPASLLP 292
>PDXB_PSESM (Q884R9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 380 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/92 (41%), Positives = 55/92 (59%), Gaps = 4/92 (4%) Frame = -2 Query: 627 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 460 DVISLH LDK+ T+HL++ RL +++ A L+NASRG V+D AL + + + Sbjct: 168 DVISLHTPLDKSGQSPTWHLLDEARLRQLRQGAWLINASRGAVVDNRALHDVMLEREDLQ 227 Query: 459 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 LDV+E EP + LA++ + PHIA S Sbjct: 228 AVLDVWEGEPQVNVALADL-CVIGTPHIAGYS 258
>SERA_SHIFL (P0A9T3) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 450 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 298 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECOLI (P0A9T0) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 450 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 298 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECOL6 (P0A9T1) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 450 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 298 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>SERA_ECO57 (P0A9T2) D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (PGDH)| Length = 409 Score = 61.6 bits (148), Expect = 2e-09 Identities = 37/117 (31%), Positives = 65/117 (55%), Gaps = 6/117 (5%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +DV+SLH + +T +++ + +++MK ++L+NASRG V+D AL + L + + + Sbjct: 203 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 262 Query: 450 DVFEDE------PYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGY 298 DVF E P+ P L E N ++ PHI +++ +E + L V GK+ Y Sbjct: 263 DVFPTEPATNSDPFTSP-LCEFDNVLLTPHIGGSTQEAQENI----GLEVAGKLIKY 314
>LDHD_LACDE (P26297) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 60.8 bits (146), Expect = 3e-09 Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 14/125 (11%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +ADVISLH H+IN + +A MK++ V+VN SRGP++D A++ L + +F Sbjct: 198 QADVISLHVPDVPANVHMINDKSIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKVFGYA 257 Query: 453 LDVFEDE-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVL 316 +DV+E E + LA++ N +V PH A + M A N L Sbjct: 258 MDVYEGEVGVFNEDREGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDNNL 317 Query: 315 GKIKG 301 ++G Sbjct: 318 ELVEG 322
>CTBPA_XENLA (Q9YHU0) C-terminal-binding protein A (CtBP)| Length = 440 Score = 60.5 bits (145), Expect = 4e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 230 SDCVTLHCGLNEHNHHLINDFTIKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 289 Query: 450 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 290 DVHESEPFSFTQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>CTBP1_MOUSE (O88712) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 230 SDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 289 Query: 450 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 290 DVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>CTBP1_HUMAN (Q13363) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| Length = 440 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 230 SDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 289 Query: 450 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 290 DVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 341
>LDHD_ECOLI (P52643) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| (Fermentative lactate dehydrogenase) Length = 329 Score = 60.1 bits (144), Expect = 5e-09 Identities = 30/67 (44%), Positives = 41/67 (61%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 E+DVISLH L YHL+N MK ++VN SRG +ID A +E LK + +G Sbjct: 197 ESDVISLHCPLTPENYHLLNEAAFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLG 256 Query: 453 LDVFEDE 433 +DV+E+E Sbjct: 257 MDVYENE 263
>CTBP1_RAT (Q9Z2F5) C-terminal-binding protein 1 (EC 1.1.1.-) (CtBP1)| (C-terminal-binding protein 3) (CtBP3) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) Length = 430 Score = 60.1 bits (144), Expect = 5e-09 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D ++LH L++ +HLIN + M++ A LVN +RG ++DE AL + LK + L Sbjct: 219 SDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 278 Query: 450 DVFEDEP--YMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKG 301 DV E EP + + L + N + PH A S+ M AA + I G Sbjct: 279 DVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITG 330
>PDXB_VIBPA (Q87MN8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 377 Score = 59.7 bits (143), Expect = 7e-09 Identities = 34/91 (37%), Positives = 53/91 (58%), Gaps = 4/91 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 ++D+I+LH + K T+HLI+ + L ++ + +L+NA+RGPV+D AL + L Sbjct: 168 QSDIITLHTPITKDGLHPTHHLIDEKVLNGLRGDQILINAARGPVVDNQALKQRLMKQDG 227 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 373 F LDVFE EP + L + A PH+A Sbjct: 228 FTAALDVFEFEPEVDMELLPLL-AFATPHVA 257
>PDXB_SALTY (P60802) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.3 bits (142), Expect = 9e-09 Identities = 40/102 (39%), Positives = 54/102 (52%), Gaps = 4/102 (3%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ L A Sbjct: 167 EADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQP 226 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + L E + + HIA +T EG A Sbjct: 227 LSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>PDXB_SALTI (P60801) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 59.3 bits (142), Expect = 9e-09 Identities = 40/102 (39%), Positives = 54/102 (52%), Gaps = 4/102 (3%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EADV++ H L K T HL + + +K A+L+NA RGPV+D AL+ L A Sbjct: 167 EADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQP 226 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + L E + + HIA +T EG A Sbjct: 227 LSVVLDVWEGEPDLNVALLEAVD-IGTSHIAG---YTLEGKA 264
>PDXB_WIGBR (Q8D2P6) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/93 (39%), Positives = 54/93 (58%), Gaps = 4/93 (4%) Frame = -2 Query: 630 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 463 +D+I+LH L + T+HLIN + L +K +L+N SRG VID +L+ LK Sbjct: 167 SDIITLHVPLTYSGKYPTWHLINKKILLDLKDNCILINTSRGSVIDNNSLLNILKEGKPI 226 Query: 462 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 RV LDV+E+EP + L + + + PHIA S Sbjct: 227 RVVLDVWENEPLICSKLLSLID-IGTPHIAGHS 258
>PDXB_YERPS (Q668W7) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 57.8 bits (138), Expect = 3e-08 Identities = 40/103 (38%), Positives = 57/103 (55%), Gaps = 5/103 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EADV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ L+ Sbjct: 167 EADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKK 226 Query: 465 FRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 227 LSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_YERPE (Q8D0U3) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 375 Score = 57.8 bits (138), Expect = 3e-08 Identities = 40/103 (38%), Positives = 57/103 (55%), Gaps = 5/103 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EADV++ H L+KT + H+ + E LA + +L+NA RG V+D AL+ L+ Sbjct: 167 EADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKK 226 Query: 465 FRVGLDVFEDEPYMK-PGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + P LA + + PHIA +T EG A Sbjct: 227 LSVVLDVWEPEPDLSLPLLARVD--IGTPHIAG---YTLEGKA 264
>PDXB_COXBU (Q83AR8) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 366 Score = 57.4 bits (137), Expect = 3e-08 Identities = 41/93 (44%), Positives = 54/93 (58%), Gaps = 4/93 (4%) Frame = -2 Query: 627 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 460 D++ LH L KT TYHLI+ L M+K +VL+NA RG VID AL L+ + + Sbjct: 169 DLVCLHTPLVKTGNFPTYHLIDNRFLKMLKPGSVLLNAGRGAVIDNNAL---LQCDHVIT 225 Query: 459 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASASK 361 LDV+E+EP + L E K + PHIA SK Sbjct: 226 C-LDVWENEPTVNLQLLE-KTTIATPHIAGYSK 256
>DHGY_HYPME (P36234) Glycerate dehydrogenase (EC 1.1.1.29) (NADH-dependent| hydroxypyruvate reductase) (HPR) (GDH) (Hydroxypyruvate dehydrogenase) (Glyoxylate reductase) Length = 321 Score = 57.0 bits (136), Expect = 5e-08 Identities = 30/93 (32%), Positives = 48/93 (51%) Frame = -2 Query: 618 SLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 439 SL+ T + N + + + A++VN +RG ++D +V L+A + G DVF Sbjct: 208 SLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFA 267 Query: 438 DEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 EP + G ++ N + PHI SA+ RE MA Sbjct: 268 GEPNINEGYYDLPNTFLFPHIGSAATQAREDMA 300
>CTBPB_XENLA (Q9W758) C-terminal-binding protein B (TCF-3 corepressor CtBP)| (XCtBP) Length = 437 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 2/88 (2%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D I+LH L++ +HLIN + M++ LVN +RG ++DE AL + LK + L Sbjct: 233 SDCITLHCNLNEHNHHLINDFTIKQMRQGCFLVNTARGGLVDEKALAQALKDGRIRGAAL 292 Query: 450 DVFEDEP--YMKPGLAEMKNAVVVPHIA 373 DV E EP + + L + N + PH A Sbjct: 293 DVHESEPFSFSQGPLKDAPNLICTPHTA 320
>LDHD_TREPA (O83080) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 56.6 bits (135), Expect = 6e-08 Identities = 38/110 (34%), Positives = 53/110 (48%), Gaps = 14/110 (12%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +DVISLH K ++HLIN + +A MK LVN +RG VID AL++ L + L Sbjct: 199 SDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVIDSQALLDSLDKGKIAGAAL 258 Query: 450 DVFEDE-PYMKPG-------------LAEMKNAVVVPHIASASKWTREGM 343 D +E E PY+ L + + PHIA ++ E M Sbjct: 259 DAYEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETAIENM 308
>DDH_ZYMMO (P30799) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/66 (43%), Positives = 41/66 (62%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D+ISLH L +H+IN E LA KK LVN SRG ++D A+++ LKA + Sbjct: 200 SDIISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVDTKAVIKSLKAKHLGGYAA 259 Query: 450 DVFEDE 433 DV+E+E Sbjct: 260 DVYEEE 265
>YGDH_SCHPO (O94574) Putative 2-hydroxyacid dehydrogenase C1773.17c (EC| 1.-.-.-) Length = 340 Score = 55.8 bits (133), Expect = 1e-07 Identities = 29/92 (31%), Positives = 49/92 (53%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +DVIS++ L T+ LI+ + MK ++N +RG +I+E A ++ +K+ + R GL Sbjct: 215 SDVISINCPLTPATHDLISTKEFEKMKDGVYIINTARGAIINEDAFIKAIKSGKVARAGL 274 Query: 450 DVFEDEPYMKPGLAEMKNAVVVPHIASASKWT 355 DVF +EP E + PH + +T Sbjct: 275 DVFLNEPTPNKFWLECDKVTIQPHCGVYTNFT 306
>PDXB_SHEON (Q8ECR2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 376 Score = 55.8 bits (133), Expect = 1e-07 Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 4/94 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 EAD+ISLH + +T T HL + RL +K L+N RG VID AL++ + Sbjct: 168 EADIISLHVPITRTGEHKTLHLFDEARLMSLKANIWLINCCRGDVIDNQALIKVKQQRDD 227 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 ++ LDV+E EP P L PHIA S Sbjct: 228 LKLVLDVWEGEPNPMPELVPFAE-FATPHIAGYS 260
>VANH_ENTFC (Q05709) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin resistance protein vanH) Length = 322 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 14/100 (14%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D+++LH L+ T+++I+ E++ MK+ A L+N RGP++D LV+ L+ + L Sbjct: 195 SDIVTLHVPLNTDTHYIISHEQIQRMKQGAFLINTGRGPLVDTYELVKALENGKLGGAAL 254 Query: 450 DVFEDEP-------YMKP-------GLAEMKNAVVVPHIA 373 DV E E KP L M N ++ PH A Sbjct: 255 DVLEGEEEFFYSDCTQKPIDNQFLLKLQRMPNVIITPHTA 294
>LDHD_LACHE (P30901) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 336 Score = 55.1 bits (131), Expect = 2e-07 Identities = 40/125 (32%), Positives = 58/125 (46%), Gaps = 14/125 (11%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +ADVISLH H+IN + +A MK V+VN SRG ++D A++ L + +F Sbjct: 198 QADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFV 257 Query: 453 LDVFEDE-----------PYMKPGLAEM---KNAVVVPHIASASKWTREGMATLAALNVL 316 +D +EDE + LA++ N +V PH A + M A N L Sbjct: 258 MDTYEDEVGVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNL 317 Query: 315 GKIKG 301 I G Sbjct: 318 KLING 322
>DDH_HAEIN (P44501) 2-hydroxyacid dehydrogenase homolog (EC 1.1.1.-)| Length = 331 Score = 54.3 bits (129), Expect = 3e-07 Identities = 27/67 (40%), Positives = 41/67 (61%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++ VI+LH YHL+N E A MK ++VN SRG +ID A ++ LK + +G Sbjct: 197 KSHVITLHCPATPENYHLLNCEAFAKMKDGVMIVNTSRGSLIDTQAAIDALKQRKIGALG 256 Query: 453 LDVFEDE 433 +DV+E+E Sbjct: 257 MDVYENE 263
>SERA_SCHPO (P87228) Putative D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)| (3-PGDH) Length = 466 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 13/103 (12%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD +SLH T ++I+ + A MK+ + L+NASRG V+D ALV+ K+ + + Sbjct: 248 ADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIPALVDASKSGKIAGAAI 307 Query: 450 DVFEDEP-------------YMKPGLAEMKNAVVVPHIASASK 361 DV+ EP L KN ++ PHI +++ Sbjct: 308 DVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTE 350
>PDXB_ECOL6 (Q8FFH2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.9 bits (128), Expect = 4e-07 Identities = 37/101 (36%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Frame = -2 Query: 630 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 463 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 462 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + L + K + PHIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELLK-KVDIGTPHIAG---YTLEGKA 264
>LDHD_STAES (Q8CN22) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 53.9 bits (128), Expect = 4e-07 Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 15/102 (14%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + + Sbjct: 198 DADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNNGTLSGAA 257 Query: 453 LDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 373 +D +E D+P + L +N +V PHIA Sbjct: 258 IDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>LDHD_STAEQ (Q5HLA0) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 53.9 bits (128), Expect = 4e-07 Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 15/102 (14%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K ++HL + +KK AVLVNA+RG VI+ L+E + + Sbjct: 198 DADIISLHVPANKDSFHLFDNNMFKNVKKGAVLVNAARGAVINTPDLIEAVNNGTLSGAA 257 Query: 453 LDVFE---------------DEPYMKPGLAEMKNAVVVPHIA 373 +D +E D+P + L +N +V PHIA Sbjct: 258 IDTYENEANYFTFDCSNQTIDDPILL-DLIRNENILVTPHIA 298
>VANH_ENTFA (Q47748) D-specific alpha-keto acid dehydrogenase (EC 1.1.1.-)| (Vancomycin B-type resistance protein vanHB) Length = 323 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 15/101 (14%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 +D+++LH L T HLI ++ MK+ A L+N RG ++D +LVE L + + L Sbjct: 196 SDIVTLHVPLCADTRHLIGQRQIGEMKQGAFLINTGRGALVDTGSLVEALGSGKLGGAAL 255 Query: 450 DVFE---------------DEPYMKPGLAEMKNAVVVPHIA 373 DV E D P++ L M N ++ PH A Sbjct: 256 DVLEGEDQFVYTDCSQKVLDHPFLSQ-LLRMPNVIITPHTA 295
>PDXB_SHIFL (Q83QR1) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Frame = -2 Query: 630 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 463 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 462 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + L K + PHIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>PDXB_ECO57 (Q8XCR0) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 53.1 bits (126), Expect = 7e-07 Identities = 37/101 (36%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Frame = -2 Query: 630 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 463 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 462 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + L K + PHIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELL-TKVDIGTPHIAG---YTLEGKA 264
>LDHD_STAAR (Q6GDS2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 53.1 bits (126), Expect = 7e-07 Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L++ + + Sbjct: 198 DADIISLHVPANKESYHLFDKTMFDHVKKGAILVNAARGAVINTPDLIDAVNDGTLLGAA 257 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 373 +D +E+E L E + +V PHIA Sbjct: 258 IDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>PDXB_PHOPR (Q6LNU2) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 391 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/96 (36%), Positives = 53/96 (55%), Gaps = 9/96 (9%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKAN-- 472 + DVI++H + K T+HLIN + ++ +A+L+NA+RGPV D AL + L+ + Sbjct: 168 QCDVITVHTPITKDGEYPTHHLINEAFIDALQPDAILINAARGPVTDNQALKKALQLSQS 227 Query: 471 ---PMFRVGLDVFEDEPYMKPGLAEMKNAVVVPHIA 373 LDVFE EP++ L + A PHIA Sbjct: 228 GLGKKLTAVLDVFEFEPHVDLELLPLL-AFATPHIA 262
>LDHD_LEUMC (P51011) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 52.8 bits (125), Expect = 9e-07 Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD ISL+ +HLIN + +A MK V++NA+RG ++D A+++ L + + G Sbjct: 198 QADAISLYVPGVPENHHLINADAIAKMKDGVVIMNAARGNLMDIDAIIDGLNSGKISDFG 257 Query: 453 LDVFEDEP--YMKPGLAE------------MKNAVVVPHIA 373 +DV+E+E MK GL + +N ++ PH A Sbjct: 258 MDVYENEVACSMKIGLVKNSPDAKIADLIARENVMITPHTA 298
>PDXB_ERWCT (Q6D2N5) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 52.8 bits (125), Expect = 9e-07 Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 4/102 (3%) Frame = -2 Query: 633 EADVISLHPVL----DKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 +AD+++LH L T+HL++ L +L+NA RGPV+D AL+E L+ Sbjct: 167 DADILTLHTPLYLDGPYRTHHLVDATVLNAFADGRILINACRGPVVDNAALLEALQQGKK 226 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + L + + HIA +T EG A Sbjct: 227 LSVILDVWEPEPGLSTDLLARVD-IGTAHIAG---YTLEGKA 264
>SERA_YEAST (P40054) D-3-phosphoglycerate dehydrogenase 1 (EC 1.1.1.95) (3-PGDH| 1) Length = 469 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 14/105 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++D ++LH T +++ + A MK A ++NASRG V+D +L++ +KAN + Sbjct: 250 KSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAA 309 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 361 LDV+ EP K G L + N ++ PHI +++ Sbjct: 310 LDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>SER33_YEAST (P40510) D-3-phosphoglycerate dehydrogenase 2 (EC 1.1.1.95) (3-PGDH| 2) Length = 469 Score = 52.4 bits (124), Expect = 1e-06 Identities = 31/105 (29%), Positives = 54/105 (51%), Gaps = 14/105 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++D ++LH T +++ + A MK A ++NASRG V+D +L++ +KAN + Sbjct: 250 KSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAA 309 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIASASK 361 LDV+ EP K G L + N ++ PHI +++ Sbjct: 310 LDVYPHEP-AKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTE 353
>LDHD_STAAW (Q8NUT2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + Sbjct: 198 DADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAA 257 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 373 +D +E+E L E + +V PHIA Sbjct: 258 IDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAU (P72357) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + Sbjct: 198 DADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAA 257 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 373 +D +E+E L E + +V PHIA Sbjct: 258 IDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAS (Q6G6F1) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + Sbjct: 198 DADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAA 257 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 373 +D +E+E L E + +V PHIA Sbjct: 258 IDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAN (P99116) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + Sbjct: 198 DADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAA 257 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 373 +D +E+E L E + +V PHIA Sbjct: 258 IDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAM (P63940) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + Sbjct: 198 DADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAA 257 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 373 +D +E+E L E + +V PHIA Sbjct: 258 IDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>LDHD_STAAC (Q5HD29) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 14/101 (13%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+ISLH +K +YHL + +KK A+LVNA+RG VI+ L+ + + Sbjct: 198 DADIISLHVPANKESYHLFDKAMFDHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAA 257 Query: 453 LDVFEDEPYMKPG--------------LAEMKNAVVVPHIA 373 +D +E+E L E + +V PHIA Sbjct: 258 IDTYENEAAYFTNDWTNKDIDDKTLLELIEHERILVTPHIA 298
>DHD2_LACPA (P17584) D-2-hydroxyisocaproate dehydrogenase (EC 1.1.1.-)| (D-HICDH) Length = 333 Score = 51.6 bits (122), Expect = 2e-06 Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 15/102 (14%) Frame = -2 Query: 633 EADVISLH-PVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRV 457 ++DVI LH P +++ T H+IN +MK A+++N +R +ID A++ +LK+ + V Sbjct: 197 QSDVIDLHVPGIEQNT-HIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGV 255 Query: 456 GLDVFEDEPYMKPGLAE--------------MKNAVVVPHIA 373 G+D +E E LA+ M N V+ PHIA Sbjct: 256 GIDTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIA 297
>PDXB_SHESP (Q56731) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 51.2 bits (121), Expect = 2e-06 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = -2 Query: 627 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 460 DVISLH + KT T++L + RL +K+ L+N RG VID AL++ P + Sbjct: 56 DVISLHVPITKTGEHKTWYLFDEARLNSLKQGTWLLNCCRGEVIDNQALIKVKLERPDIK 115 Query: 459 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 + LDV+E EP L + + PHIA S Sbjct: 116 LVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>PDXB_BACTN (Q8A2E4) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 348 Score = 51.2 bits (121), Expect = 2e-06 Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 15/157 (9%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 E D+I+ H L K TYHL + ++++ V++N SRG VI+ AL+E + + Sbjct: 168 ECDIITFHVPLYKEGKYKTYHLADGNFFRSLQRKPVVINTSRGEVIETNALLEAINNGII 227 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWG 286 +DV+E EP + L E K + PHIA GY G Sbjct: 228 SDAVIDVWEHEPEINRELLE-KVLIGTPHIA-----------------------GYSADG 263 Query: 285 NPNAVEPFLDE-----------EATPPPACPSIVNAK 208 NA LD E TPP ++ AK Sbjct: 264 KANATRMSLDSICRFFHLSATYEITPPAPSSPLIEAK 300
>PDXB_ECOLI (P05459) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 378 Score = 50.8 bits (120), Expect = 3e-06 Identities = 36/101 (35%), Positives = 52/101 (51%), Gaps = 4/101 (3%) Frame = -2 Query: 630 ADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMF 463 AD+++ H L K T HL + + + +K A+L+NA RG V+D AL+ L Sbjct: 168 ADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKL 227 Query: 462 RVGLDVFEDEPYMKPGLAEMKNAVVVPHIASASKWTREGMA 340 V LDV+E EP + L + K + HIA +T EG A Sbjct: 228 SVVLDVWEGEPELNVELLK-KVDIGTSHIAG---YTLEGKA 264
>PDXB_SHEVI (Q56733) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| (Fragment) Length = 274 Score = 50.4 bits (119), Expect = 4e-06 Identities = 35/92 (38%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Frame = -2 Query: 627 DVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFR 460 DVISLH + KT T++L + RL +K L+N RG VID AL++ + P + Sbjct: 56 DVISLHVPIIKTGEHKTWYLFDETRLNSLKPGTWLLNCCRGEVIDNRALIKVKQQRPDIK 115 Query: 459 VGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 + LDV+E EP L + + PHIA S Sbjct: 116 LVLDVWEGEPNPMHELIPLVE-LATPHIAGYS 146
>YGT5_YEAST (P53100) Putative 2-hydroxyacid dehydrogenase YGL185C (EC 1.-.-.-)| Length = 379 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Frame = -2 Query: 591 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPYMKPGL 412 T HLIN + L +LVN RG ++D A+ + L + +GLDVF EP + + Sbjct: 270 TEHLINRKFLEHCNPGLILVNLGRGKILDLRAVSDALVTGRINHLGLDVFNKEPEIDEKI 329 Query: 411 AEMKNAV-VVPHIASASKWTREGMATLAALNVLGKIKG 301 + PH+ SA+K E LA +L + G Sbjct: 330 RSSDRLTSITPHLGSATKDVFEQSCELALTRILRVVSG 367
>LDHD_LACPL (Q88VJ2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH)| Length = 332 Score = 48.5 bits (114), Expect = 2e-05 Identities = 24/67 (35%), Positives = 39/67 (58%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +ADVI+LH K YH++N + + MK A ++N +RG +ID L++ L + + Sbjct: 198 QADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAA 257 Query: 453 LDVFEDE 433 LD +E E Sbjct: 258 LDTYEYE 264
>PDXB_BLOFL (Q7VRU9) Erythronate-4-phosphate dehydrogenase (EC 1.1.1.-)| Length = 372 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Frame = -2 Query: 633 EADVISLHPVLDKT----TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPM 466 ++D+++LH L T T+H+IN + L + ++L+N SRG V++ L+ L+ Sbjct: 168 KSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVVNNDDLLAILRCGKK 227 Query: 465 FRVGLDVFEDEPYMKPGLAEMKNAVVVPHIASAS 364 V LDV+E EP + L + + HIA S Sbjct: 228 INVILDVWESEPKLSLPLLSYVD-IGTAHIAGYS 260
>YP113_YEAST (Q02961) Putative 2-hydroxyacid dehydrogenase YPL113C (EC 1.-.-.-)| Length = 396 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Frame = -2 Query: 630 ADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGL 451 AD+I L +T ++IN + LA K +VN RG IDE L++ L++ + GL Sbjct: 277 ADLIILALPSTASTNNIINRKSLAWCKDGVRIVNVGRGTCIDEDVLLDALESGKVASCGL 336 Query: 450 DVFE-DEPYMKPGLAEMKNAVVVPHIAS 370 DVF+ +E +K L + +PHI S Sbjct: 337 DVFKNEETRVKQELLRRWDVTALPHIGS 364
>FDH1_ORYSA (Q9SXP2) Formate dehydrogenase 1, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 1) (FDH 1) Length = 376 Score = 47.8 bits (112), Expect = 3e-05 Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 + DVI ++ L + T + N ER+A MKK ++VN +RG ++D A+ + + + G Sbjct: 245 KCDVIVINTPLTEKTRGMFNKERIAKMKKGVIIVNNARGAIMDTQAVADACSSGQVAGYG 304 Query: 453 LDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 364 DV+ +P K M N + PHI+ + Sbjct: 305 GDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 335
>LDHD_PEDAC (Q59642) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 331 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 14/118 (11%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +A+VI+LH K YH+++ + M+ ++N +RG ++D AL++ L + + Sbjct: 197 QANVITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAA 256 Query: 453 LDVFE-----------DEPYMKP---GLAEMKNAVVVPHIASASKWTREGMATLAALN 322 LD +E D+P P L +N ++ PH A ++ + M +A N Sbjct: 257 LDTYENEVGIFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALDN 314
>LDHD_STRP1 (Q99ZM2) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 47.0 bits (110), Expect = 5e-05 Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 1/71 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD++SLH HL N + KK A+L+N +RG VI+ L++ L A + G Sbjct: 198 DADLVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAG 257 Query: 453 LDVFEDE-PYM 424 +D +E E PY+ Sbjct: 258 IDTYEFEGPYI 268
>FDH_HORVU (Q9ZRI8) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 377 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 + DV+ ++ L + T + N E++A MKK ++VN +RG ++D A+ + + + G Sbjct: 246 KCDVVVINTPLTEKTRGMFNKEKIAKMKKGVIIVNNARGAIMDTQAVADACSSGHIAGYG 305 Query: 453 LDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 364 DV+ +P K M N + PHI+ + Sbjct: 306 GDVWFPQPAPKDHPWRYMPNHAMTPHISGTT 336
>LDHD_STRA5 (Q8E0N5) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 45.4 bits (106), Expect = 1e-04 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 EAD++SLH HL N + KK A+L+N +RG +++ L+E L + G Sbjct: 198 EADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAG 257 Query: 453 LDVFEDE-PYM 424 +D +E E PY+ Sbjct: 258 IDTYEFEGPYI 268
>LDHD_LACPE (P26298) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 332 Score = 45.1 bits (105), Expect = 2e-04 Identities = 23/67 (34%), Positives = 38/67 (56%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +ADVI+LH K YH++N + + MK A ++N +RG +ID L++ L + + Sbjct: 198 QADVITLHVPALKDNYHMLNADAFSKMKDGAYILNFARGTLIDSEDLIKALDSGKVAGAA 257 Query: 453 LDVFEDE 433 L +E E Sbjct: 258 LVTYEYE 264
>LDHD_STRA3 (Q8E6A9) D-lactate dehydrogenase (EC 1.1.1.28) (D-LDH) (D-specific| D-2-hydroxyacid dehydrogenase) Length = 330 Score = 43.9 bits (102), Expect = 4e-04 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD++SLH HL N + KK A+L+N +RG +++ L+E L + G Sbjct: 198 KADLVSLHMPPTAENTHLFNLDMFKQFKKGAILMNMARGALVETKDLLEALDQGLLEGAG 257 Query: 453 LDVFEDE-PYM 424 +D +E E PY+ Sbjct: 258 IDTYEFEGPYI 268
>FDH2_ORYSA (Q67U69) Formate dehydrogenase 2, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase 2) (FDH 2) Length = 378 Score = 43.1 bits (100), Expect = 7e-04 Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 + DV+ ++ L + T + N ER+A MKK +VN +RG ++D A+ + + + G Sbjct: 247 KCDVVVINMPLTEKTRGMFNKERIAKMKKGVTIVNNARGAIMDTQAVADACASGHVAGYG 306 Query: 453 LDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 364 DV+ +P K M N + PH + + Sbjct: 307 GDVWFPQPAPKDHPWRYMPNHAMTPHCSGTT 337
>FDH_SOLTU (Q07511) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 381 Score = 42.7 bits (99), Expect = 9e-04 Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 + D++ ++ L + T + + ER+A +KK ++VN +RG ++D A+V+ + + Sbjct: 250 KCDIVVINTPLTEKTKGMFDKERIAKLKKGVLIVNNARGAIMDTQAVVDACNSGHIAGYS 309 Query: 453 LDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 364 DV+ +P K M N + PHI+ + Sbjct: 310 GDVWYPQPAPKDHPWRYMPNQAMTPHISGTT 340
>FDH_NEUCR (Q07103) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 375 Score = 42.0 bits (97), Expect = 0.002 Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 6/96 (6%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 + DV++++ L + T L N E ++ MKK + LVN +RG ++ + + E LK+ + G Sbjct: 222 QCDVVTINCPLHEKTQGLFNKELISKMKKGSWLVNTARGAIVVKEDVAEALKSGHLRGYG 281 Query: 453 LDVFEDEPYMKP-GLAEMKNA-----VVVPHIASAS 364 DV+ +P + L KN +VPH++ S Sbjct: 282 GDVWFPQPAPQDHPLRYAKNPFGGGNAMVPHMSGTS 317
>FDH_PSESR (P33160) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 400 Score = 42.0 bits (97), Expect = 0.002 Identities = 23/69 (33%), Positives = 38/69 (55%) Frame = -2 Query: 627 DVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLD 448 DV++L+ L T H+IN E L + K+ A +VN +RG + D A+ L++ + D Sbjct: 249 DVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGD 308 Query: 447 VFEDEPYMK 421 V+ +P K Sbjct: 309 VWFPQPAPK 317
>FDH_ARATH (Q9S7E4) Formate dehydrogenase, mitochondrial precursor (EC| 1.2.1.2) (NAD-dependent formate dehydrogenase) (FDH) Length = 384 Score = 40.0 bits (92), Expect = 0.006 Identities = 23/91 (25%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 + DVI ++ L + T + N E + +KK ++VN +RG +++ A+V+ +++ + Sbjct: 253 KCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVESGHIGGYS 312 Query: 453 LDVFEDEPYMKP-GLAEMKNAVVVPHIASAS 364 DV++ +P K M N + PH + + Sbjct: 313 GDVWDPQPAPKDHPWRYMPNQAMTPHTSGTT 343
>FDH2_YEAST (Q08987) Formate dehydrogenase 2 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 2) Length = 376 Score = 38.5 bits (88), Expect = 0.017 Identities = 21/71 (29%), Positives = 40/71 (56%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++DV++++ L K + L N + ++ MK A LVN +RG + + E +K+ + G Sbjct: 235 QSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYG 294 Query: 453 LDVFEDEPYMK 421 DV++ +P K Sbjct: 295 GDVWDKQPAPK 305
>FDH1_YEAST (Q08911) Formate dehydrogenase 1 (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase 1) Length = 376 Score = 38.5 bits (88), Expect = 0.017 Identities = 21/71 (29%), Positives = 40/71 (56%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 ++DV++++ L K + L N + ++ MK A LVN +RG + + E +K+ + G Sbjct: 235 QSDVVTINCPLHKDSRGLFNKKLISHMKDGAYLVNTARGAICVAEDVAEAVKSGKLAGYG 294 Query: 453 LDVFEDEPYMK 421 DV++ +P K Sbjct: 295 GDVWDKQPAPK 305
>FDH_PICAN (P33677) Formate dehydrogenase (EC 1.2.1.2) (NAD-dependent formate| dehydrogenase) (FDH) Length = 361 Score = 34.3 bits (77), Expect = 0.32 Identities = 21/71 (29%), Positives = 37/71 (52%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVG 454 +AD+++++ L + L+N E L KK A LVN +RG + + +K+ + G Sbjct: 220 QADIVTINCPLHAGSKGLVNAELLKHFKKGAWLVNTARGAICVAEDVAAAVKSGQLRGYG 279 Query: 453 LDVFEDEPYMK 421 DV+ +P K Sbjct: 280 GDVWFPQPAPK 290
>YCDW_ECOLI (P75913) Putative 2-hydroxyacid dehydrogenase ycdW (EC 1.-.-.-)| Length = 325 Score = 32.3 bits (72), Expect = 1.2 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Frame = -2 Query: 591 TYHLINPERLAMMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFEDEPY-MKPG 415 T +IN + L + A L+N +RG + E L+ L + + LDVF EP + Sbjct: 217 TVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESP 276 Query: 414 LAEMKNAVVVPHIASASK 361 L + + PH+A+ ++ Sbjct: 277 LWQHPRVTITPHVAAITR 294
>NIP7_YEAST (Q08962) 60S ribosome subunit biogenesis protein NIP7| Length = 181 Score = 31.2 bits (69), Expect = 2.7 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Frame = -2 Query: 429 YMKPGLAEMKNAVVVPHIASAS----KWTREGMATL--AALNVLGKIKGYPVWGNPNAVE 268 Y+ +A++ +V P++ S K+T+ G L +L VL K Y +W PN Sbjct: 46 YVPDHVAKLATSVARPNLMSLGICLGKFTKTGKFRLHITSLTVLAKHAKYKIWIKPNGEM 105 Query: 267 PFL 259 PFL Sbjct: 106 PFL 108
>FDH_EMENI (Q03134) Probable formate dehydrogenase (EC 1.2.1.2) (NAD-dependent| formate dehydrogenase) (FDH) Length = 377 Score = 30.4 bits (67), Expect = 4.6 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 17/88 (19%) Frame = -2 Query: 633 EADVISLHPVLDKTTYHLINPERLAMMK-----------------KEAVLVNASRGPVID 505 + DV++++ L + T L N E ++ MK K + LVN +RG ++ Sbjct: 217 QCDVVTINCPLHEKTRGLFNKELISKMKPGKSALLYLIIPMLMYHKGSWLVNTARGAIVV 276 Query: 504 EVALVEHLKANPMFRVGLDVFEDEPYMK 421 + + E LK+ + G DV+ +P K Sbjct: 277 KEDVAEALKSGHLRGYGGDVWFPQPAPK 304
>NUOL_BUCAI (P57262) NADH-quinone oxidoreductase chain L (EC 1.6.99.5) (NADH| dehydrogenase I, chain L) (NDH-1, chain L) Length = 614 Score = 29.6 bits (65), Expect = 7.8 Identities = 13/50 (26%), Positives = 24/50 (48%) Frame = +2 Query: 473 LALRCSTSATSSITGPRLAFTSTASFFIIASRSGFIRWYVVLSSTGCRLI 622 ++ R S + I L T +F+++ + +G++RWYV G I Sbjct: 555 ISKRLSADPLNKIINYFLKVTQIFNFYLLKTSNGYVRWYVASMILGINFI 604 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,198,259 Number of Sequences: 219361 Number of extensions: 1775461 Number of successful extensions: 5508 Number of sequences better than 10.0: 119 Number of HSP's better than 10.0 without gapping: 5267 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5486 length of database: 80,573,946 effective HSP length: 107 effective length of database: 57,102,319 effective search space used: 5881538857 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
