ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbaal3g01 |
|---|---|
| Clone Library Name | barley_pub |
>LCFA_SALTY (P63521) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 112 bits (279), Expect = 2e-24 Identities = 62/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P EAK++ DD E G GELC+K P + YW+RP+ T E I G+ TGD +D Sbjct: 385 PSTEAKLVDDDDNEVAPGEAGELCVKGPQVMLGYWQRPDATDE-IIKDGWLHTGDIAVMD 443 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 EDG+ I+ R D++ V G+ + EIE V+++H V E A +G+P + GE + +V Sbjct: 444 EDGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHSGVQEVAAVGVPSGSSGEAVKLFVV 502 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K+ PALT +AL ++ + L YK+P ++ + LP++ +GK+ Sbjct: 503 KKD-----------PALTDDALITFCRRHLTGYKVPKQVEFREELPKSNVGKI 544
>LCFA_SALTI (P63522) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 561 Score = 112 bits (279), Expect = 2e-24 Identities = 62/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P EAK++ DD E G GELC+K P + YW+RP+ T E I G+ TGD +D Sbjct: 385 PSTEAKLVDDDDNEVAPGEAGELCVKGPQVMLGYWQRPDATDE-IIKDGWLHTGDIAVMD 443 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 EDG+ I+ R D++ V G+ + EIE V+++H V E A +G+P + GE + +V Sbjct: 444 EDGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHSGVQEVAAVGVPSGSSGEAVKLFVV 502 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K+ PALT +AL ++ + L YK+P ++ + LP++ +GK+ Sbjct: 503 KKD-----------PALTDDALITFCRRHLTGYKVPKQVEFREELPKSNVGKI 544
>LCFA_ECOLI (P69451) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 110 bits (275), Expect = 4e-24 Identities = 61/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P EAK++ DD E G GELC+K P + YW+RP+ T E I G+ TGD +D Sbjct: 385 PSTEAKLVDDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDE-IIKNGWLHTGDIAVMD 443 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E+G+ I+ R D++ V G+ + EIE V+++H V E A +G+P + GE + +V Sbjct: 444 EEGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVV 502 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K+ P+LT E+L ++ + +L YK+P + D LP++ +GK+ Sbjct: 503 KKD-----------PSLTEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKI 544
>LCFA_ECOL6 (P69452) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 110 bits (275), Expect = 4e-24 Identities = 61/173 (35%), Positives = 97/173 (56%), Gaps = 1/173 (0%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P EAK++ DD E G GELC+K P + YW+RP+ T E I G+ TGD +D Sbjct: 385 PSTEAKLVDDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDE-IIKNGWLHTGDIAVMD 443 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E+G+ I+ R D++ V G+ + EIE V+++H V E A +G+P + GE + +V Sbjct: 444 EEGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVV 502 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K+ P+LT E+L ++ + +L YK+P + D LP++ +GK+ Sbjct: 503 KKD-----------PSLTEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKI 544
>LCFA_ECO57 (Q8XDR6) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) (Acyl-CoA synthetase) Length = 561 Score = 109 bits (273), Expect = 8e-24 Identities = 60/173 (34%), Positives = 97/173 (56%), Gaps = 1/173 (0%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P EAK++ DD E G GELC++ P + YW+RP+ T E I G+ TGD +D Sbjct: 385 PSTEAKLVDDDDNEVSPGQPGELCVRGPQVMLGYWQRPDATDE-IIKNGWLHTGDIAVMD 443 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E+G+ I+ R D++ V G+ + EIE V+++H V E A +G+P + GE + +V Sbjct: 444 EEGFLRIVDRKK-DMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVV 502 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K+ P+LT E+L ++ + +L YK+P + D LP++ +GK+ Sbjct: 503 KKD-----------PSLTEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKI 544
>LCFA_BACSU (P94547) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 560 Score = 106 bits (264), Expect = 8e-23 Identities = 57/153 (37%), Positives = 84/153 (54%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+ +K P + K YW +PE TA DG F TGD +DE+G+F I R DI+ GG Sbjct: 404 GEIIVKGPQVMKGYWNKPEETAAVLRDGWLF-TGDMGYMDEEGFFYIADRKK-DIIIAGG 461 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 Y + E+E L EH+ + E V G+PD GE + A +V K+ A+ E+ Sbjct: 462 YNIYPREVEEALYEHEAIQEIVVAGVPDSYRGETVKAFVVLKKGAKADTEE--------- 512 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L ++++ +LAPYK+P LP+ A+GK+ Sbjct: 513 -LDAFARSRLAPYKVPKAYEFRKELPKTAVGKI 544
>FAT2_SCHPO (O74976) Putative peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 512 Score = 105 bits (261), Expect = 2e-22 Identities = 66/186 (35%), Positives = 96/186 (51%), Gaps = 1/186 (0%) Frame = -1 Query: 715 MVHGKKVQSVNLXPRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFID 539 +VH K SV VE KI+ G E G GE+C++ ++ K Y P SF Sbjct: 323 LVH--KPHSVGKPFGVELKILDQKGNEMPQGKEGEICVRGINVTKGYLNNPAANKSSFTK 380 Query: 538 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 359 FF+TGD +D+DGY I GR +++ GG K+S EI+AVL++H V E +P Sbjct: 381 DRFFRTGDEGKLDKDGYVFITGRIK-ELVNRGGEKISPAEIDAVLMQHPDVSEAVCFAVP 439 Query: 358 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 179 DE YG+ I A I P + +T + L + + K+A +KIP + + D +P+ Sbjct: 440 DEKYGQDIQAAINP----------VAGKTVTPKQLHDYLEQKVAAFKIPKKFYFTDRIPK 489 Query: 178 NAMGKV 161 A GKV Sbjct: 490 TATGKV 495
>DHBE_BACSU (P40871) 2,3-dihydroxybenzoate-AMP ligase (EC 6.3.2.-)| (Dihydroxybenzoic acid-activating enzyme) Length = 539 Score = 103 bits (258), Expect = 4e-22 Identities = 61/181 (33%), Positives = 98/181 (54%), Gaps = 2/181 (1%) Frame = -1 Query: 694 QSVNLXPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 518 Q + P E ++ D + K G G L + P + Y+K E A SF + GF++TG Sbjct: 353 QGKPMSPYDEMRVWDDHDRDVKPGETGHLLTRGPYTIRGYYKAEEHNAASFTEDGFYRTG 412 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D V + DGY ++ GR I + GG K++A E+E LL H V + A++ +PD+ GE Sbjct: 413 DIVRLTRDGYIVVEGRAKDQINR-GGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGER 471 Query: 337 ICAIIVPKEDARERAEQASKPALTLEALTSWSKDK-LAPYKIPTRLHLWDSLPRNAMGKV 161 C I+P+++A + AE L ++ +++ LA YKIP R+ +S P+ +GKV Sbjct: 472 SCVFIIPRDEAPKAAE-----------LKAFLRERGLAAYKIPDRVEFVESFPQTGVGKV 520 Query: 160 N 158 + Sbjct: 521 S 521
>LCFA_YERPE (Q8ZES9) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 99.0 bits (245), Expect = 1e-20 Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 1/173 (0%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P + ++ DDG + + G GEL ++ P + YW+RP+ T + DG + TGD T+D Sbjct: 385 PSTDVRLRDDDGNDVELGKPGELWVRGPQVMLGYWQRPDATDDVLKDG-WLATGDIATMD 443 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 EDG+ I+ R D++ V G+ + EIE V+ H VLE AV+G+P+E GE + + V Sbjct: 444 EDGFLRIVDRKK-DMILVSGFNVYPNEIEEVVALHAKVLESAVIGVPNEVSGEAV-KVFV 501 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K DA +LT E L + + L YK+P + D LP++ +GK+ Sbjct: 502 VKNDA----------SLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSNVGKI 544
>ENTE_ECOLI (P10378) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 97.4 bits (241), Expect = 4e-20 Identities = 59/180 (32%), Positives = 92/180 (51%), Gaps = 1/180 (0%) Frame = -1 Query: 694 QSVNLXPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 518 Q + P E + +G G VG L + P F+ Y+K P+ A +F GF+ +G Sbjct: 355 QGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSG 414 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D +++D +GY + GR I + GG K++A EIE +LL H V+ A++ + DE GE Sbjct: 415 DLISIDPEGYITVQGREKDQINR-GGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEK 473 Query: 337 ICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 CA +V KE P ++ + +A +K+P R+ DSLP A+GKV+ Sbjct: 474 SCAYLVVKE-----------PLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVD 522
>ENTE_ECO57 (Q8XBV3) Enterobactin synthetase component E (Enterochelin synthase| E) [Includes: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) (Dihydroxybenzoic acid-activating enzyme); S-dihydroxybenzoyltransferase (EC 2.3.1.-)] Length = 536 Score = 97.4 bits (241), Expect = 4e-20 Identities = 59/180 (32%), Positives = 92/180 (51%), Gaps = 1/180 (0%) Frame = -1 Query: 694 QSVNLXPRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 518 Q + P E + +G G VG L + P F+ Y+K P+ A +F GF+ +G Sbjct: 355 QGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFYCSG 414 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D +++D +GY + GR I + GG K++A EIE +LL H V+ A++ + DE GE Sbjct: 415 DLISIDPEGYITVQGREKDQINR-GGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEK 473 Query: 337 ICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 CA +V KE P ++ + +A +K+P R+ DSLP A+GKV+ Sbjct: 474 SCAYLVVKE-----------PLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVD 522
>LCFA_HAEIN (P46450) Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (Long-chain| acyl-CoA synthetase) Length = 562 Score = 97.1 bits (240), Expect = 5e-20 Identities = 60/173 (34%), Positives = 90/173 (52%), Gaps = 1/173 (0%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P + KII DDG++ K G GEL +K + + YW+RPE T+E DG + TGD V +D Sbjct: 387 PNTDIKIIKDDGSDAKIGEAGELWVKGDQVMRGYWQRPEATSEVLKDG-WMATGDIVIMD 445 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E I+ R DI+ V G+ + EIE V++ + V E +G+P GE I +V Sbjct: 446 ESYSLRIVDRKK-DIILVSGFNVYPNEIEDVVMLNYKVSEAVAIGVPHAVSGETIKIFVV 504 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K+D +LT + L + + L YK+P + D LP+ +GK+ Sbjct: 505 KKDD-----------SLTRDELRNHCRQYLTGYKVPKEIEFRDELPKTNVGKI 546
>FAT2_YEAST (P38137) Peroxisomal-coenzyme A synthetase (EC 6.-.-.-)| Length = 543 Score = 96.7 bits (239), Expect = 7e-20 Identities = 56/185 (30%), Positives = 97/185 (52%), Gaps = 3/185 (1%) Frame = -1 Query: 706 GKKVQSVNLXPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDG- 536 GK+ P+ +I+DD VGE+ I+ ++ Y P+ E+F Sbjct: 351 GKRKPGTVGQPQGVTVVILDDNDNVLPPGKVGEVSIRGENVTLGYANNPKANKENFTKRE 410 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 +F+TGD D +G+ ++ GR +++ GG K+S +E++ ++L H + E G+PD Sbjct: 411 NYFRTGDQGYFDPEGFLVLTGRIK-ELINRGGEKISPIELDGIMLSHPKIDEAVAFGVPD 469 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + YG+V+ A IV K+ + +T E L ++ K LA +KIPT+++ D LP+ Sbjct: 470 DMYGQVVQAAIVLKKGEK----------MTYEELVNFLKKHLASFKIPTKVYFVDKLPKT 519 Query: 175 AMGKV 161 A GK+ Sbjct: 520 ATGKI 524
>ACSA_BACSU (P39062) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) (Acetyl-CoA synthase) Length = 572 Score = 94.7 bits (234), Expect = 3e-19 Identities = 59/175 (33%), Positives = 88/175 (50%), Gaps = 3/175 (1%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKD-GVGELCIKS--PSLFKEYWKRPEVTAESFIDGGFFKTGDTVT 506 P VEA I+ + G E +G L IK PS+ W PE F+ GG++ +GD+ Sbjct: 384 PGVEAAIVDNQGNELPPYRMGNLAIKKGWPSMMHTIWNNPEKYESYFMPGGWYVSGDSAY 443 Query: 505 VDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI 326 +DE+GYF GR + D++ G ++ E+E+ L+EH + E V+G PD GE+I A Sbjct: 444 MDEEGYFWFQGRVD-DVIMTSGERVGPFEVESKLVEHPAIAEAGVIGKPDPVRGEIIKAF 502 Query: 325 IVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 I RE E + K E + + K LA + P + D LP+ GK+ Sbjct: 503 IA----LREGFEPSDK---LKEEIRLFVKQGLAAHAAPREIEFKDKLPKTRSGKI 550
>ACSA_PASMU (Q9CMW1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 93.6 bits (231), Expect = 6e-19 Identities = 60/179 (33%), Positives = 95/179 (53%), Gaps = 7/179 (3%) Frame = -1 Query: 676 PRVEAKIIMDDGTETK-DGVGELCIKSP--SLFKEYWKRPEVTAESFID----GGFFKTG 518 P + A+++ ++G + + G L IK P S+ + W PE ++ G ++ G Sbjct: 445 PGIMAEVLDENGQKCAVEQGGALAIKRPFPSMLRTIWNDPERYKSTYFPAEYGGKYYIAG 504 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D D+DGYF ILGRT+ D++ V G++L +EIE+ L+ V E AV+G PDE GE Sbjct: 505 DNAHRDKDGYFWILGRTD-DVLNVSGHRLGTMEIESALVASPKVAEAAVVGKPDEIKGEA 563 Query: 337 ICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 I A +V D R E+A + A E L +W +++ P + D+LP+ GK+ Sbjct: 564 IVAFVV-LNDFRPEGEEARQLA---EELKAWVSNEIGKIARPEDIRFADNLPKTRSGKI 618
>CAIC_PROSL (Q8GB18) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 518 Score = 92.4 bits (228), Expect = 1e-18 Identities = 51/157 (32%), Positives = 86/157 (54%), Gaps = 3/157 (1%) Frame = -1 Query: 622 VGELCIKSPS---LFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 VGE+C+K + LFKEY+ RP+ T ++ G+ TGD D++G+F + R+ +++ Sbjct: 367 VGEICVKGEAGKTLFKEYYNRPDATEKALEPDGWLHTGDYGYRDDEGFFYFVDRS-CNMI 425 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 K GG +S +EIE ++ H + + AV+G+PD+ E I A +V Sbjct: 426 KRGGENVSCIEIENIIASHPKIQDVAVIGVPDDIRDEAIKAFVV----------LVDGET 475 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L+ EA ++ + +A +K+P+ + LPRN GKV Sbjct: 476 LSEEAFFAFCEQNMAKFKVPSAVEFKQGLPRNCSGKV 512
>FADK_ECOLI (P38135) Short-chain-fatty-acid--CoA ligase (EC 6.2.1.-) (Acyl-CoA| synthetase) Length = 548 Score = 92.4 bits (228), Expect = 1e-18 Identities = 57/172 (33%), Positives = 93/172 (54%), Gaps = 2/172 (1%) Frame = -1 Query: 670 VEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDED 494 VE K++ D G GE + P++F Y+ PE+TA + + G++ +GD +DE Sbjct: 365 VEIKVVDDARKTLPPGCEGEEASRGPNVFMGYFDEPELTARALDEEGWYYSGDLCRMDEA 424 Query: 493 GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPK 314 GY I GR DI+ GG +S+ E+E +LL+H + + V+ + DE GE CA +V K Sbjct: 425 GYIKITGR-KKDIIVRGGENISSREVEDILLQHPKIHDACVVAMSDERLGERSCAYVVLK 483 Query: 313 EDARERAEQASKPALTLEALTS-WSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A +L+LE + + +S+ ++A YK P + + + LPR GK+ Sbjct: 484 ---------APHHSLSLEEVVAFFSRKRVAKYKYPEHIVVIEKLPRTTSGKI 526
>ACS1_KLULA (O60011) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 707 Score = 92.4 bits (228), Expect = 1e-18 Identities = 55/157 (35%), Positives = 85/157 (54%), Gaps = 4/157 (2%) Frame = -1 Query: 619 GELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIM 452 G L IK P S + WK + ++++ G++ TGD V D+DG+F ILGR + D++ Sbjct: 515 GVLAIKRPWPSFARTIWKNNDRFLDTYLKPYPGYYFTGDGVARDKDGFFWILGRVD-DVV 573 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 V G++LS EIEA ++E D V ECAV+G DE G+ + A +V K + A S+ Sbjct: 574 NVSGHRLSTAEIEAAIIEDDMVAECAVVGFNDELTGQAVAAFVVLKNKSSLTAASESELQ 633 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + L + + P+ P + L D LP+ GK+ Sbjct: 634 DIKKHLIITVRKDIGPFAAPKLIVLVDDLPKTRSGKI 670
>ACSA_RALEU (P31638) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 660 Score = 91.7 bits (226), Expect = 2e-18 Identities = 57/180 (31%), Positives = 95/180 (52%), Gaps = 8/180 (4%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF----IDGGFFKTG 518 P + A I+ + G + +G G + + P++ + W PE +S+ + G + G Sbjct: 452 PGIMAAIVDETGHDVPNGNGGILVVKRPWPAMIRTIWGDPERFRKSYFPEELGGKLYLAG 511 Query: 517 DTVTVDED-GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D D+D GYF I+GR + D++ V G+++ +EIE+ L+ + V E AV+G PD+ GE Sbjct: 512 DGSIRDKDTGYFTIMGRID-DVLNVSGHRMGTMEIESALVSNPLVAEAAVVGRPDDMTGE 570 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ICA +V K +R E+A K A L +W ++ P P + D+LP+ GK+ Sbjct: 571 AICAFVVLKR-SRPTGEEAVKIATELR---NWVGKEIGPIAKPKDIRFGDNLPKTRSGKI 626
>ACSA_NITEU (Q82SI5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 655 Score = 91.3 bits (225), Expect = 3e-18 Identities = 54/180 (30%), Positives = 90/180 (50%), Gaps = 8/180 (4%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGVGE-LCIKSP--SLFKEYWKRPEVTAESFID-----GGFFKT 521 P ++A ++ + G + G G L IK P S+ + W PE +++ G ++ Sbjct: 447 PGIDAAVVDETGHPVEQGKGGFLVIKRPFPSMLRTLWNDPERFRKTYFPTDIAGGRYYLA 506 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 GD+ D+DGYF I+GR + D++ V G++L +EIE+ L+ H V E AV+G P E GE Sbjct: 507 GDSAHRDQDGYFWIMGRVD-DVLNVSGHRLGTMEIESALVAHPLVAEAAVVGKPHEIKGE 565 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 V+ A + RE+ + A L W ++ P + ++LP+ GK+ Sbjct: 566 VVVAFVT----LREKLPDDQRAAEIAATLREWVASEIGAIARPEEIRFGENLPKTRSGKI 621
>ACSA_RALSO (Q8XY11) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 660 Score = 90.9 bits (224), Expect = 4e-18 Identities = 56/180 (31%), Positives = 94/180 (52%), Gaps = 8/180 (4%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF----IDGGFFKTG 518 P + A I+ + G + DG G + + P++ + W PE +S+ + G + G Sbjct: 452 PGIMAAIVDETGQDLPDGQGGILVVKRPWPAMIRTIWGDPERFRKSYFPAELGGKLYLAG 511 Query: 517 D-TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D +V E GYF I+GR + D++ V G+++ +EIE+ L+ + V E AV+G PD+ GE Sbjct: 512 DGSVRDKETGYFTIMGRID-DVLNVSGHRMGTMEIESALVANPLVAEAAVVGRPDDMTGE 570 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ICA +V K R ++A + A L +W ++ P P + D+LP+ GK+ Sbjct: 571 AICAFVVLKR-TRPNGDEARQIATDLR---NWVGKEIGPIAKPKDIRFGDNLPKTRSGKI 626
>MENE_BACSU (P23971) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 486 Score = 90.5 bits (223), Expect = 5e-18 Identities = 55/153 (35%), Positives = 81/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+ +K P++ K Y+ R SF G+ KTGD +D +G+ +L R +D++ GG Sbjct: 334 GEIMVKGPNVMKSYFNRESANEASF-QNGWLKTGDLGYLDNEGFLYVLDR-RSDLIISGG 391 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 + E+E+VLL H V E V G D+ +G+V A +V KP E Sbjct: 392 ENIYPAEVESVLLSHPAVAEAGVSGAEDKKWGKVPHAYLV-----------LHKPVSAGE 440 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 LT + K++LA YKIP + + D LPRNA K+ Sbjct: 441 -LTDYCKERLAKYKIPAKFFVLDRLPRNASNKL 472
>CAIC_SALTY (Q8ZRX4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 90.1 bits (222), Expect = 6e-18 Identities = 56/173 (32%), Positives = 91/173 (52%), Gaps = 4/173 (2%) Frame = -1 Query: 667 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 EA+I D G +GE+CIK ++FKEY+ +PE TA++ G+ TGD+ D Sbjct: 350 EAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAKALEPEGWLHTGDSGYQD 409 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 EDGYF + R +++K GG +S +E+E ++ H + + V+G+ D E I A IV Sbjct: 410 EDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIV 468 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E L+ S+ ++ +A +K+P+ + + LPRN GK+ Sbjct: 469 LNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKI 511
>CAIC_SALTI (Q8Z9L4) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 89.7 bits (221), Expect = 8e-18 Identities = 56/173 (32%), Positives = 90/173 (52%), Gaps = 4/173 (2%) Frame = -1 Query: 667 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 EA+I D G +GE+CIK ++FKEY+ +PE TA + G+ TGD+ D Sbjct: 350 EAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQD 409 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 EDGYF + R +++K GG +S +E+E ++ H + + V+G+ D E I A IV Sbjct: 410 EDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIV 468 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E L+ S+ ++ +A +K+P+ + + LPRN GK+ Sbjct: 469 LNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKI 511
>CAIC_SALPA (Q5PIL0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 89.7 bits (221), Expect = 8e-18 Identities = 56/173 (32%), Positives = 90/173 (52%), Gaps = 4/173 (2%) Frame = -1 Query: 667 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 EA+I D G +GE+CIK ++FKEY+ +PE TA + G+ TGD+ D Sbjct: 350 EAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQD 409 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 EDGYF + R +++K GG +S +E+E ++ H + + V+G+ D E I A IV Sbjct: 410 EDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIV 468 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E L+ S+ ++ +A +K+P+ + + LPRN GK+ Sbjct: 469 LNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKI 511
>MENE_BACCR (Q816I1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 89.4 bits (220), Expect = 1e-17 Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 7/164 (4%) Frame = -1 Query: 631 KDGV-------GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILG 473 KDGV GE+ +K P++ Y+ R + T E+ I G+ TGD +DE+G+ +L Sbjct: 321 KDGVVVPPLVEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDEEGFLYVLD 379 Query: 472 RTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERA 293 R +D++ GG + +IE VLL H V E V+G+ D+ +G+V A +V Sbjct: 380 R-RSDLIISGGENIYPAQIEEVLLSHPAVAEAGVVGMSDDKWGQVPAAFVV--------- 429 Query: 292 EQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A+T E + + ++KLA YK+P + + LPRNA K+ Sbjct: 430 ---KSGAVTEEEILHFCEEKLAKYKVPKKACFLEELPRNASKKL 470
>CAIC_SALCH (Q57TJ0) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 517 Score = 89.0 bits (219), Expect = 1e-17 Identities = 56/173 (32%), Positives = 90/173 (52%), Gaps = 4/173 (2%) Frame = -1 Query: 667 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 EA+I D G +GE+CIK ++FKEY+ +PE TA + G+ TGD+ D Sbjct: 350 EAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAGALEPEGWLHTGDSGYQD 409 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 EDGYF + R +++K GG +S +E+E ++ H + + V+G+ D E I A IV Sbjct: 410 EDGYFYFVDR-RCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIV 468 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E L+ S+ ++ +A +K+P+ + + LPRN GK+ Sbjct: 469 LNEG----------ETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKI 511
>MENE_BACCZ (Q632I5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 88.6 bits (218), Expect = 2e-17 Identities = 54/164 (32%), Positives = 87/164 (53%), Gaps = 7/164 (4%) Frame = -1 Query: 631 KDGV-------GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILG 473 KDGV GE+ +K P++ Y+ R + T E+ I G+ TGD +DE+G+ +L Sbjct: 321 KDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDEEGFLYVLD 379 Query: 472 RTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERA 293 R +D++ GG + +IE VLL H V E V+G+ D+ +G+V A +V + Sbjct: 380 R-RSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWGQVPAAFVVKSGE----- 433 Query: 292 EQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 +T E + + ++KLA YK+P + + LPRNA K+ Sbjct: 434 -------ITEEEILHFCEEKLAKYKVPKKAWFLEELPRNASKKL 470
>MENE_LISMF (Q71YZ5) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 88.6 bits (218), Expect = 2e-17 Identities = 55/153 (35%), Positives = 83/153 (54%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+ +K PS+ Y + T SF+DG +FKTGD +DE+G+ +L R +D++ GG Sbjct: 318 GEILLKGPSITPGYLHNKKATEASFVDG-WFKTGDIGYLDEEGFLFVLER-RSDLIISGG 375 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 + EIE V+ E++ V E AV+G PD+ +G V A IV +E E Sbjct: 376 ENIYPTEIEHVISEYEGVKEVAVIGKPDDKWGSVPVAFIVAEETFDE------------A 423 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L + LA YKIP ++ + + LP+ A GK+ Sbjct: 424 ELRLICETNLAGYKIPKQITIVEKLPKTASGKI 456
>MENE_BACHK (Q6HC29) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 482 Score = 88.2 bits (217), Expect = 2e-17 Identities = 54/164 (32%), Positives = 86/164 (52%), Gaps = 7/164 (4%) Frame = -1 Query: 631 KDGV-------GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILG 473 KDGV GE+ +K P++ Y+ R + T E+ I G+ TGD +DE+G+ +L Sbjct: 321 KDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDEEGFLYVLD 379 Query: 472 RTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERA 293 R +D++ GG + +IE VLL H V E V+G+ D+ +G+V A +V + E Sbjct: 380 R-RSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWGQVPAAFVVKSGEVTE-- 436 Query: 292 EQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E + + ++KLA YK+P + + LPRNA K+ Sbjct: 437 ----------EEILHFCEEKLAKYKVPKKACFLEELPRNASKKL 470
>MENE_BACAN (Q81K97) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 88.2 bits (217), Expect = 2e-17 Identities = 54/164 (32%), Positives = 87/164 (53%), Gaps = 7/164 (4%) Frame = -1 Query: 631 KDGV-------GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILG 473 KDGV GE+ +K P++ Y+ R + T E+ I G+ TGD +DE+G+ +L Sbjct: 320 KDGVVVPPFAEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDLGYLDEEGFLYVLD 378 Query: 472 RTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERA 293 R +D++ GG + +IE VLL H V E V+G+ D+ +G+V A +V + Sbjct: 379 R-RSDLIISGGENIYPAQIEEVLLSHPMVAEAGVVGMTDDKWGQVPAAFVVKSGE----- 432 Query: 292 EQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 +T E + + ++KLA YK+P + + LPRNA K+ Sbjct: 433 -------ITEEEILHFCEEKLAKYKVPKKACFLEELPRNASKKL 469
>ACSA_HELPY (O25686) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 662 Score = 87.8 bits (216), Expect = 3e-17 Identities = 56/181 (30%), Positives = 102/181 (56%), Gaps = 9/181 (4%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRPEVTAESF-----IDGGF-FK 524 P + A+++ +DGT+TK G G LCI P S+ + W + +S+ ++G + + Sbjct: 448 PGIHAEVLNEDGTKTKPGEQGFLCITKPWPSMIRNIWGDEKRYIDSYFSQIKLNGEYVYL 507 Query: 523 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 344 +GD VDE+GY I+GRT+ DI+ V G+++ E+E+ + +H+ V ECAV+G+PD G Sbjct: 508 SGDGAIVDENGYITIIGRTD-DIVNVSGHRIGTAEVESAISKHEMVAECAVVGIPDAIKG 566 Query: 343 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 164 E + A +V + A+ ++ + + + S K+A K+ +++ LP+ GK Sbjct: 567 EGLFAFVVLCDGAKCNLGESLELLKEMNHILSIEIGKIA--KLDNVMYV-PGLPKTRSGK 623 Query: 163 V 161 + Sbjct: 624 I 624
>MENE_LISMO (P58730) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 86.7 bits (213), Expect = 7e-17 Identities = 54/153 (35%), Positives = 83/153 (54%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+ +K PS+ Y + T SF+DG +FKTGD +DE+G+ ++ R +D++ GG Sbjct: 318 GEILLKGPSITPGYLHNKKATEASFVDG-WFKTGDIGYLDEEGFLFVVER-RSDLIISGG 375 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 + EIE V+ E+ V E AV+G PD+ +G V A IV +E E + Sbjct: 376 ENIYPTEIEHVIGEYVAVKEVAVIGQPDDKWGSVPVAFIVAEETFDE------------D 423 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L + LA YKIP ++ + + LP+ A GK+ Sbjct: 424 ELQLICQTNLASYKIPKQIIIVEKLPKTASGKI 456
>MENE_BACC1 (Q72YK9) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 481 Score = 86.7 bits (213), Expect = 7e-17 Identities = 54/164 (32%), Positives = 85/164 (51%), Gaps = 7/164 (4%) Frame = -1 Query: 631 KDGV-------GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILG 473 KDGV GE+ +K P++ Y+ R + T E+ I G+ TGD +DE+G+ +L Sbjct: 320 KDGVVVPAFTEGEIVVKGPNVTGGYFNREDATRET-IQNGWLHTGDIGYLDEEGFLYVLD 378 Query: 472 RTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERA 293 R +D++ GG + +IE VLL H V E V+G+ D+ +G+V A +V + E Sbjct: 379 R-RSDLIISGGENIYPAQIEEVLLSHPAVAEAGVVGMTDDKWGQVPVAFVVKSGEVTE-- 435 Query: 292 EQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E + + + KLA YK+P + + LPRNA K+ Sbjct: 436 ----------EEIIHFCEAKLAKYKVPKKACFLEELPRNASKKL 469
>ACS1_YEAST (Q01574) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 713 Score = 86.3 bits (212), Expect = 9e-17 Identities = 52/174 (29%), Positives = 88/174 (50%), Gaps = 8/174 (4%) Frame = -1 Query: 658 IIMDDGT----ETKDGVGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTV 503 +++D T T G L +K+ PS + WK + +++++ G++ TGD Sbjct: 504 VVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAK 563 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 D+DGY ILGR + D++ V G++LS EIEA ++E V ECAV+G D+ G+ + A + Sbjct: 564 DKDGYIWILGRVD-DVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFV 622 Query: 322 VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 V K + + + L + + P+ P + L D LP+ GK+ Sbjct: 623 VLKNKSSWSTATDDELQDIKKHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKI 676
>TYCA_BREPA (P09095) Tyrocidine synthetase 1 (Tyrocidine synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1088 Score = 86.3 bits (212), Expect = 9e-17 Identities = 55/189 (29%), Positives = 92/189 (48%), Gaps = 6/189 (3%) Frame = -1 Query: 706 GKKVQSVNLXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF- 530 GK +Q+ ++ E ++ G+E GELCI L + YW RP++TAE F+D F Sbjct: 338 GKPIQNTHIYIVNEDLQLLPTGSE-----GELCIGGVGLARGYWNRPDLTAEKFVDNPFV 392 Query: 529 -----FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 365 ++TGD DG LGR + + K+ G+++ EIE+VLL H+ + E V+ Sbjct: 393 PGEKMYRTGDLAKWLTDGTIEFLGRIDHQV-KIRGHRIELGEIESVLLAHEHITEAVVIA 451 Query: 364 LPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSL 185 D+ G+ +CA + +++A T L ++ KL Y +P+ D + Sbjct: 452 REDQHAGQYLCAYYISQQEA------------TPAQLRDYAAQKLPAYMLPSYFVKLDKM 499 Query: 184 PRNAMGKVN 158 P K++ Sbjct: 500 PLTPNDKID 508
>GRSA_BREBE (P0C062) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 85.9 bits (211), Expect = 1e-16 Identities = 56/174 (32%), Positives = 87/174 (50%), Gaps = 8/174 (4%) Frame = -1 Query: 655 IMDDGTETKD--GVGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 500 I+D+ + K GELCI L + YWKRPE+T++ F+D F +KTGD Sbjct: 359 IVDENLQLKSVGEAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGEKLYKTGDQARWL 418 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 DG LGR + + K+ G+++ E+E++LL+H + E AV D +CAI V Sbjct: 419 PDGNIEYLGRIDNQV-KIRGHRVELEEVESILLKHMYISETAVSVHKDHQEQPYLCAIFV 477 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 S+ + LE L +S ++L Y IP+ D +P + GK++ Sbjct: 478 ------------SEKHIPLEQLRQFSSEELPTYMIPSYFIQLDKMPLTSNGKID 519
>ACS1_CANGA (Q6FLU2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 704 Score = 85.5 bits (210), Expect = 2e-16 Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 13/179 (7%) Frame = -1 Query: 658 IIMDD--GTETKDGVGE--LCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTV 503 +I+D G E D E L IK P S + WK + +++++ G++ TGD Sbjct: 495 VILDPTTGEEINDSHAEGVLAIKRPWPSFARTIWKNHDRFLDTYLNPYKGYYFTGDGAAR 554 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 D+DGY ILGR + D++ V G++LS EIEA ++E V ECAV+G D+ G+ + A + Sbjct: 555 DKDGYIWILGRVD-DVVNVSGHRLSTAEIEAAIIEDRMVAECAVVGFNDDLTGQAVAAFV 613 Query: 322 VPKE-----DARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 V K+ A E Q K L L + + P+ P + L D LP+ GK+ Sbjct: 614 VLKDKSTWASASEEELQDIKKHLILTV-----RKDIGPFAAPKLIVLVDDLPKTRSGKI 667
>CAIC_SHIFL (Q83MG9) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 85.5 bits (210), Expect = 2e-16 Identities = 54/173 (31%), Positives = 88/173 (50%), Gaps = 4/173 (2%) Frame = -1 Query: 667 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 EA+I D G +GE+CIK ++FKEY+ P+ TA+ G+ TGDT D Sbjct: 355 EAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRD 414 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E+G+F + R +++K GG +S +E+E ++ H + + V+G+ D E I A +V Sbjct: 415 EEGFFYFVDR-RCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVV 473 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E L+ E + + +A +K+P+ L + LPRN GK+ Sbjct: 474 LNEG----------ETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKI 516
>CAIC_ECO57 (Q8XA34) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 85.5 bits (210), Expect = 2e-16 Identities = 49/157 (31%), Positives = 82/157 (52%), Gaps = 3/157 (1%) Frame = -1 Query: 622 VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 +GE+CIK ++FKEY+ P+ TA+ G+ TGDT DE+G+F + R +++ Sbjct: 371 IGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFIDR-RCNMI 429 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 K GG +S +E+E ++ H + + V+G+ D E I A +V E Sbjct: 430 KRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEG----------ET 479 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L+ E + + +A +K+P+ L + LPRN GK+ Sbjct: 480 LSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKI 516
>BACC_BACLI (O68008) Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine Length = 6359 Score = 85.1 bits (209), Expect = 2e-16 Identities = 56/161 (34%), Positives = 80/161 (49%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGELC+ SL + Y RPE+TAE FI F ++TGD DG+ LGR + Sbjct: 1827 VGELCVGGMSLARGYLNRPELTAEKFISHPFASGERLYRTGDLARWLPDGHLEFLGRIDH 1886 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ GY++ EIE LL+ D + E AV+ D+ + + +CA IV KED Sbjct: 1887 QV-KIRGYRIELGEIENQLLKLDKIDEAAVIARKDDDHSDYLCAYIVSKED--------- 1936 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 T ++ W + +L Y IP D LP + KV+ Sbjct: 1937 ---WTSTEISEWLEKELPHYMIPAYFVRLDKLPLTSNDKVD 1974 Score = 77.0 bits (188), Expect = 5e-14 Identities = 53/174 (30%), Positives = 86/174 (49%), Gaps = 8/174 (4%) Frame = -1 Query: 655 IMDDGTETKD-GV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 500 I+D+ E + G+ GEL I + K Y +PE+T+E F+ F ++TGD + Sbjct: 5868 ILDERQEVQPVGIAGELYISGDGVAKGYLNKPELTSEKFLPNPFLPGERMYRTGDLAKMR 5927 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 DG+ LGR + + K+ GY++ EIE LL H + E AV D+ +V+CA +V Sbjct: 5928 PDGHIEYLGRIDHQV-KIRGYRIELGEIEHQLLRHSDIKEAAVAAKTDQNNDQVLCAYVV 5986 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + D +T + + ++ +L Y +P+ L D LP GKV+ Sbjct: 5987 SERD------------ITQKDIKTFLAKELPEYMVPSYLLKLDELPLTPNGKVD 6028 Score = 70.1 bits (170), Expect = 7e-12 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 8/175 (4%) Frame = -1 Query: 658 IIMDD-GTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTV 503 +IMD+ G GV GELCI L K Y R E+TAE FI F +KTGD Sbjct: 781 LIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERLYKTGDLAKW 840 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 DG +GR + + K+ G+++ EIE+ L H+ + E V DE ICA I Sbjct: 841 LPDGNIEFIGRIDHQV-KIRGFRIELGEIESRLEMHEDINETIVTVREDEESRPYICAYI 899 Query: 322 VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + ++L+ L + +KL Y IP D LP GKV+ Sbjct: 900 TANRE------------ISLDELKGFLGEKLPEYMIPAYFVKMDKLPLTKNGKVD 942 Score = 68.9 bits (167), Expect = 1e-11 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELC+ L + Y RP++T E F+ F ++TGD DG LGR + Sbjct: 3333 GELCLSGEGLARGYLNRPDLTLEKFVPNPFAPGESMYRTGDLARFLPDGQIEYLGRIDHQ 3392 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ G+++ EIE LL+ + + AV+ D+A G+ +CA IV A++A+ Sbjct: 3393 V-KIRGFRIELGEIENQLLKIEGIDAAAVMAREDQAGGKYLCAYIV--------ADKAAG 3443 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 A + L +L Y +P+ D LP A GK++ Sbjct: 3444 VADVRKCLLK----ELPDYMVPSYFVKLDQLPLTANGKID 3479 Score = 65.5 bits (158), Expect = 2e-10 Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 6/193 (3%) Frame = -1 Query: 718 CMVHGKKVQSVNLXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFID 539 C V G + + N E ++ +G GELCI + Y RP+ T E FI+ Sbjct: 4348 CPVIGTPIHNTNAYVLDENMKLLPEGV-----YGELCIAGAGVTGGYVNRPDETKEKFIE 4402 Query: 538 GGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC 377 F ++TGD DG + GR + + KV GY++ EI+ LL HD + E Sbjct: 4403 NPFAPHTKMYRTGDLARRLSDGNIELAGRIDTQV-KVRGYRIEPEEIKNRLLAHDDIKEA 4461 Query: 376 AVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHL 197 + D + +CA + L E + ++ +L Y IP+ Sbjct: 4462 FIAAREDHKGAKQLCAYFTADAE------------LPFEDIRTYLMHELPEYMIPSSFVQ 4509 Query: 196 WDSLPRNAMGKVN 158 + +P +A GK++ Sbjct: 4510 IEKMPLSANGKID 4522
>CAIC_ECOL6 (Q8FLA5) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 84.7 bits (208), Expect = 3e-16 Identities = 54/173 (31%), Positives = 88/173 (50%), Gaps = 4/173 (2%) Frame = -1 Query: 667 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 EA+I D G +GE+CIK ++FKEY+ P+ TA+ G+ TGDT D Sbjct: 355 EAEIRDDHNRPLPAGELGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRD 414 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E+G+F + R +++K GG +S +E+E ++ H + + V+G+ D E I A +V Sbjct: 415 EEGFFYFVDR-RCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVV 473 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E L+ E + + +A +K+P+ L + LPRN GK+ Sbjct: 474 LNEG----------ETLSEEEFFCFCEQNMAKFKVPSYLEIRKDLPRNCSGKI 516
>ACS2_DEBHA (Q6BS00) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 679 Score = 84.7 bits (208), Expect = 3e-16 Identities = 50/163 (30%), Positives = 92/163 (56%), Gaps = 7/163 (4%) Frame = -1 Query: 628 DGVGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNA 461 D G L +K PS+ + +K +++++ G++ TGD D DGY+ I GR + Sbjct: 476 DVEGVLAVKDTWPSMARSVYKNHTKYMDTYLNPYPGYYFTGDGAARDHDGYYWIRGRVD- 534 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED--ARERAEQ 287 D++ V G++LS EIEA L+EH+ + E AV+G+ D+ G+ + A + KE A +A++ Sbjct: 535 DVVNVSGHRLSTAEIEAALIEHNAISEAAVVGMNDDLTGQTVVAFVALKEHLIANLKADE 594 Query: 286 ASKPALTL-EALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + AL L + + + ++ P+ P + + + LP+ GK+ Sbjct: 595 SPEEALKLKKEMILQVRTQIGPFAAPKSVIIVEDLPKTRSGKI 637
>GRSA_ANEMI (P0C061) Gramicidin S synthetase 1 (Gramicidin S synthetase I)| [Includes: ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)] Length = 1098 Score = 84.3 bits (207), Expect = 3e-16 Identities = 55/174 (31%), Positives = 86/174 (49%), Gaps = 8/174 (4%) Frame = -1 Query: 655 IMDDGTETKD--GVGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 500 I+D+ + K GELCI L + YWKRPE+T++ F+D F +KTGD Sbjct: 359 IVDENLQLKSVGEAGELCIGGEGLARGYWKRPELTSQKFVDNPFVPGEKLYKTGDQARWL 418 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 DG LGR + + K+ G+++ E+E++LL+H + E AV D +CA V Sbjct: 419 SDGNIEYLGRIDNQV-KIRGHRVELEEVESILLKHMYISETAVSVHKDHQEQPYLCAYFV 477 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 S+ + LE L +S ++L Y IP+ D +P + GK++ Sbjct: 478 ------------SEKHIPLEQLRQFSSEELPTYMIPSYFIQLDKMPLTSNGKID 519
>VIBE_VIBCH (O07899) Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase (EC| 6.3.2.-) (Dihydroxybenzoic acid-activating enzyme) Length = 543 Score = 83.6 bits (205), Expect = 6e-16 Identities = 49/154 (31%), Positives = 80/154 (51%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 G L + P + Y++ + +F GF+ TGD V + +GY I+ GR I + GG Sbjct: 383 GYLLTQGPYTIRGYYRADQHNQRAFNAQGFYITGDKVKLSSEGYVIVTGRAKDQINR-GG 441 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 K++A E+E LL H V + A++ + DE GE CA+IV K + + T++ Sbjct: 442 EKIAAEEVENQLLHHPAVHDAALIAISDEYLGERSCAVIVLKPE---------QSVNTIQ 492 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + LA YKIP ++ D LP+ ++GK++ Sbjct: 493 LKRFLHQAGLADYKIPDQIQFIDQLPKTSVGKID 526
>ACS1_DEBHA (Q6BQF2) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 671 Score = 83.6 bits (205), Expect = 6e-16 Identities = 58/177 (32%), Positives = 92/177 (51%), Gaps = 7/177 (3%) Frame = -1 Query: 670 VEAKIIMD-DGTETK--DGVGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDT 512 ++AKI+ G E K D G LC+KS PS+ + + E+++ + +GD Sbjct: 462 IDAKILDPVSGKELKENDVEGVLCVKSCWPSISRGIYNDYARFIETYLKPYPNHYFSGDG 521 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 332 D DG++ ILGR + D++ V G++LS EIEA L+ H++V ECAV+G DE G+ + Sbjct: 522 AARDVDGFYWILGRVD-DVVNVSGHRLSTAEIEAALILHESVAECAVVGYADELTGQAVA 580 Query: 331 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A + K + E E K L + ++ P+ P + L D LP+ GK+ Sbjct: 581 AYVSLKSNVSEDLEVIKK------ELILTVRKEIGPFATPKTILLVDDLPKTRSGKI 631
>ACSA_PENCH (P36333) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 669 Score = 83.2 bits (204), Expect = 8e-16 Identities = 54/160 (33%), Positives = 84/160 (52%), Gaps = 4/160 (2%) Frame = -1 Query: 628 DGVGELCIKSP--SLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTNA 461 D G L K P S+ + W + +++++ G++ TGD D DGY+ I GR + Sbjct: 478 DVEGVLAFKQPWPSMARTVWGAHKRYMDTYLNVYKGYYFTGDGAGRDHDGYYWIRGRVD- 536 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D++ V G++LS EIEA LLEH +V E AV+G+ DE G+ + A + KE + EQ S Sbjct: 537 DVVNVSGHRLSTAEIEAALLEHPSVAEAAVVGIADELTGQAVNAFVSLKEG--KPTEQIS 594 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K L + + P+ P + + D LP+ GK+ Sbjct: 595 KD------LAMQVRKSIGPFAAPKAVFVVDDLPKTRSGKI 628
>CAIC_ECOLI (P31552) Probable crotonobetaine/carnitine-CoA ligase (EC 6.2.1.-)| Length = 522 Score = 83.2 bits (204), Expect = 8e-16 Identities = 53/173 (30%), Positives = 87/173 (50%), Gaps = 4/173 (2%) Frame = -1 Query: 667 EAKIIMDDGTETKDG-VGELCIKS---PSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 EA+I D G +GE+CIK ++FKEY+ P+ TA+ G+ TGDT D Sbjct: 355 EAEIRDDHNRPLPAGEIGEICIKGIPGKTIFKEYFLNPQATAKVLEADGWLHTGDTGYRD 414 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E+ +F + R +++K GG +S +E+E ++ H + + V+G+ D E I A +V Sbjct: 415 EEDFFYFVDR-RCNMIKRGGENVSCVELENIIAAHPKIQDIVVVGIKDSIRDEAIKAFVV 473 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E L+ E + + +A +K+P+ L + LPRN GK+ Sbjct: 474 LNEG----------ETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKI 516
>ACSA_SCHPO (P78773) Probable acetyl-coenzyme A synthetase (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) Length = 662 Score = 82.4 bits (202), Expect = 1e-15 Identities = 53/163 (32%), Positives = 85/163 (52%), Gaps = 4/163 (2%) Frame = -1 Query: 637 ETKDGVGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGR 470 E D G L I+SP S + W+ + ++++ GF+ TGD T D+DGY I GR Sbjct: 466 EGNDVEGVLAIRSPWPSAARTVWRGHDRYIDTYLKPYPGFYFTGDGATRDKDGYIWIRGR 525 Query: 469 TNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAE 290 + D++ + G++LS EIEA LL HD V E AV+G+ DE G+ + A I+ K E Sbjct: 526 VD-DVVNISGHRLSTAEIEAALLSHDAVAESAVVGVHDELTGQAVNAFILLKPGYEATVE 584 Query: 289 QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + + + + P+ P +L ++ LP+ GK+ Sbjct: 585 LEKELIMAV-------RSTIGPFASPRKL-IFSDLPKTRSGKI 619
>ACSA_METSO (P27095) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 82.4 bits (202), Expect = 1e-15 Identities = 53/183 (28%), Positives = 89/183 (48%), Gaps = 11/183 (6%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF------IDG--GF 530 P + I+ ++G E G G + PS+ + +W E + + + G G Sbjct: 465 PGYDISILDEEGNEVPLGSGGNIVALKPYPSMLRAFWGDKERFMKEYWQFYWDVPGRRGV 524 Query: 529 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 350 + GD D+DGYF I GR + D++ V G++++ E+E+ L+ H + E AV+G PDE Sbjct: 525 YLAGDKAQRDKDGYFFIQGRID-DVLSVAGHRIANAEVESALVAHPKIAEAAVVGKPDEV 583 Query: 349 YGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 170 GE I A ++ R P L +A+ ++ + L P PT +H + LP+ Sbjct: 584 KGESIVAFVI------LRVGNEPSPELAKDAI-AFVRKTLGPVAAPTEVHFVNDLPKTRS 636 Query: 169 GKV 161 GK+ Sbjct: 637 GKI 639
>MENE_OCEIH (Q8ENZ7) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 480 Score = 82.0 bits (201), Expect = 2e-15 Identities = 57/181 (31%), Positives = 91/181 (50%) Frame = -1 Query: 703 KKVQSVNLXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFK 524 KK+ S P A++ + + +GE+ +K P + K Y+KR E E F + + Sbjct: 308 KKIGSAG-KPLFPAQLKIAHNENNPNQIGEILVKGPMVTKGYYKRAETNKEVF-ENNWLH 365 Query: 523 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 344 TGD +DE GY ++ R N D++ GG + EIE VL++ + + E V G P+E +G Sbjct: 366 TGDMGYLDEQGYLYVVDRRN-DLIISGGENIYPSEIENVLVQIEGIEEAGVKGSPNEEWG 424 Query: 343 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 164 V A IV S+P ++ + + + LA YK P +H+ + LPRNA K Sbjct: 425 MVPIAFIV-----------CSRP-ISENEIAAHLEKYLAKYKRPKEIHVVNELPRNAANK 472 Query: 163 V 161 + Sbjct: 473 L 473
>ACS2_ASHGO (Q750T7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 687 Score = 82.0 bits (201), Expect = 2e-15 Identities = 55/179 (30%), Positives = 89/179 (49%), Gaps = 14/179 (7%) Frame = -1 Query: 655 IMDDGTETKDGVGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGY 488 + D E D G L IKSP S+ + W + E+++ G++ TGD D DGY Sbjct: 466 VTGDELEGNDVEGVLAIKSPWPSMARSVWNNHDRYIETYLKPYPGYYFTGDGAGRDHDGY 525 Query: 487 FIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED 308 + I GR + D++ V G++LS EIEA L EH+ V + AV+G+ DE G+ + A + KE Sbjct: 526 YWIRGRVD-DVVNVSGHRLSTAEIEAALSEHEGVSQAAVVGIADELTGQAVVAFVSLKEG 584 Query: 307 ARERAEQASKP------ALTLEA----LTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + P + L+ L + ++ P+ P + + D LP+ GK+ Sbjct: 585 YGRGSSTDTDPESIAPDVVPLDTLRRELVLQVRAEIGPFAAPKSVIVVDDLPKTRSGKI 643
>TYCB_BREPA (O30408) Tyrocidine synthetase 2 (Tyrocidine synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D Length = 3587 Score = 81.6 bits (200), Expect = 2e-15 Identities = 60/191 (31%), Positives = 93/191 (48%), Gaps = 8/191 (4%) Frame = -1 Query: 706 GKKVQSVNLXPRVEAKIIMDDGTETK--DGVGELCIKSPSLFKEYWKRPEVTAESFIDGG 533 GK +Q+ L I+DD + K +GELCI SL + YW RPE+TAE F+D Sbjct: 2851 GKPIQNTKLY-------IVDDQLQLKAPGQMGELCISGLSLARGYWNRPELTAEKFVDNP 2903 Query: 532 F------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAV 371 F ++TGD DG LGR + + K+ G+++ E+E+VLL +DTV E A Sbjct: 2904 FVPGTKMYRTGDLARWLPDGTIEYLGRIDHQV-KIRGHRVELGEVESVLLRYDTVKEAAA 2962 Query: 370 LGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWD 191 + D+ +CA V AE + PA L ++ +++L Y +P + Sbjct: 2963 ITHEDDRGQAYLCAYYV--------AEGEATPA----QLRAYMENELPNYMVPAFFIQLE 3010 Query: 190 SLPRNAMGKVN 158 +P K++ Sbjct: 3011 KMPLTPNDKID 3021 Score = 76.3 bits (186), Expect = 9e-14 Identities = 53/161 (32%), Positives = 75/161 (46%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDG------GFFKTGDTVTVDEDGYFIILGRTNA 461 VGE+CI L + YWK+PE+TAE F+ +KTGD DG +GR + Sbjct: 1841 VGEICIGGHGLARGYWKKPELTAEKFVANPAVPGERMYKTGDLGRWLHDGTIDFIGRVD- 1899 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D +KV GY++ EIEAVLL +D E V+ D+ + A + Sbjct: 1900 DQIKVRGYRIEVGEIEAVLLAYDQTNEAIVVAYQDDRGDSYLAAYV------------TG 1947 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 K A+ L + +L Y +PT L D+ P GKV+ Sbjct: 1948 KTAIEESELRAHLLRELPAYMVPTYLIQLDAFPLTPNGKVD 1988 Score = 72.8 bits (177), Expect = 1e-12 Identities = 51/174 (29%), Positives = 85/174 (48%), Gaps = 8/174 (4%) Frame = -1 Query: 655 IMDDGTETKDG--VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 500 I+D+G + K VGEL I ++ + Y +PE+TAE F+D + ++TGD Sbjct: 793 ILDEGLQLKPEGIVGELYISGANVGRGYLHQPELTAEKFLDNPYQPGERMYRTGDLALWL 852 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 DG LGR + + K+ G+++ EIE+ LL H + E V+ DE G+ +CA +V Sbjct: 853 PDGQLEFLGRIDHQV-KIRGHRIELGEIESRLLNHPAIKEAVVIDRADETGGKFLCAYVV 911 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 ++ AL+ E + ++ L Y IP+ + +P GK + Sbjct: 912 LQK------------ALSDEEMRAYLAQALPEYMIPSFFVTLERIPVTPNGKTD 953
>MENE_LISIN (Q92AY8) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 467 Score = 81.6 bits (200), Expect = 2e-15 Identities = 53/153 (34%), Positives = 81/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+ +K PS+ Y + TA++FID G+FKTGD +DE+G+ +L R +D++ GG Sbjct: 318 GEILLKGPSITPGYLHNEKATAKAFID-GWFKTGDIGYLDEEGFLFVLER-RSDLIISGG 375 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 + EIE V+ ++ V E AV+G D +G V A IV E E Sbjct: 376 ENIYPTEIEHVIGAYEAVEEVAVVGKSDAKWGSVPVAFIVVNEGFDE------------G 423 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L + LA +KIP ++ + + LP+ A GK+ Sbjct: 424 VLKDICQTNLASFKIPKQITIVEHLPKTASGKI 456
>LUCI_LUCMI (Q26304) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 80.9 bits (198), Expect = 4e-15 Identities = 53/182 (29%), Positives = 93/182 (51%), Gaps = 4/182 (2%) Frame = -1 Query: 691 SVNLXPRVEAKIIMDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 S + P + K+I D T+ GV GE+C+K PSL Y PE T E+ + G+ T Sbjct: 364 SGKVVPLFKVKVI-DLDTKKTLGVNRRGEICVKGPSLMLGYSNNPEATRETIDEEGWLHT 422 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 GD DED +F I+ R + ++K GY++ E+E+VLL+H + + V G+PD GE Sbjct: 423 GDIGYYDEDEHFFIVDRLKS-LIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPDAGE 481 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYK-IPTRLHLWDSLPRNAMGK 164 + A++V ++ +T + + + ++ +K + + D +P+ GK Sbjct: 482 LPGAVVVMEKG----------KTMTEKEIVDYVNSQVVNHKRLRGGVRFVDEVPKGLTGK 531 Query: 163 VN 158 ++ Sbjct: 532 ID 533
>ACS2_YEAST (P52910) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 80.5 bits (197), Expect = 5e-15 Identities = 53/168 (31%), Positives = 84/168 (50%), Gaps = 9/168 (5%) Frame = -1 Query: 637 ETKDGVGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGR 470 E D G L +KSP S+ + W + ++++ G + TGD D DGY+ I GR Sbjct: 472 EGNDVEGVLAVKSPWPSMARSVWNHHDRYMDTYLKPYPGHYFTGDGAGRDHDGYYWIRGR 531 Query: 469 TNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE-----DA 305 + D++ V G++LS EIEA + H+ V E AV+G+PDE G+ + A + K+ +A Sbjct: 532 VD-DVVNVSGHRLSTSEIEASISNHENVSEAAVVGIPDELTGQTVVAYVSLKDGYLQNNA 590 Query: 304 RERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E + P L + ++ P+ P + L LPR GK+ Sbjct: 591 TEGDAEHITPDNLRRELILQVRGEIGPFASPKTIILVRDLPRTRSGKI 638
>ACS2_CANGA (Q6FXI2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 683 Score = 80.5 bits (197), Expect = 5e-15 Identities = 53/168 (31%), Positives = 85/168 (50%), Gaps = 9/168 (5%) Frame = -1 Query: 637 ETKDGVGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGR 470 E D G L +KSP S+ + W ++++ G++ TGD D DGY+ I GR Sbjct: 473 EGNDVEGVLAVKSPWPSMARSVWNDHVRYVDTYMKPYPGYYFTGDGAGRDHDGYYWIRGR 532 Query: 469 TNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE-----DA 305 + D++ V G++LS EIEA L+ H+ + E AV+G+ DE G+ + A + KE DA Sbjct: 533 VD-DVVNVSGHRLSTAEIEACLVNHENISETAVVGINDELTGQAVIAFVSLKEGYLQNDA 591 Query: 304 RERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E + P+ L + ++ P+ P + L LP+ GK+ Sbjct: 592 PEGDAEHITPSNLRRELILQVRGEIGPFASPKCIILVRDLPKTRSGKI 639
>ACS1_ASHGO (Q758X0) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 694 Score = 80.5 bits (197), Expect = 5e-15 Identities = 51/162 (31%), Positives = 81/162 (50%), Gaps = 9/162 (5%) Frame = -1 Query: 619 GELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIM 452 G L +K P S + W + +++++ G++ GD D G+ ILGR + D++ Sbjct: 502 GVLAVKQPWPSFTRTIWNNHDRYLDTYLNPYKGYYFAGDGAARDSQGFIWILGRVD-DVV 560 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE-----DARERAEQ 287 V G++LS E+EA +++ V ECAV+G DE G+ I A +V K+ A ER Q Sbjct: 561 NVSGHRLSTAEVEAAIIQESMVAECAVVGFADELTGQAIAAFVVLKQKSSWNTASERELQ 620 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K L L + + P+ P + L D LP+ GK+ Sbjct: 621 EIKKHLILSV-----RRDIGPFAAPKLIVLVDDLPKTRSGKI 657
>ACS2_KLULA (Q9Y7B5) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 684 Score = 80.5 bits (197), Expect = 5e-15 Identities = 56/172 (32%), Positives = 86/172 (50%), Gaps = 11/172 (6%) Frame = -1 Query: 643 GTETK--DGVGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFI 482 G E K D G L +KSP S+ + W E+++ G++ TGD D DGY+ Sbjct: 469 GEELKGNDVEGVLAVKSPWPSMARSVWNNHARYFETYLKPYPGYYFTGDGAGRDHDGYYW 528 Query: 481 ILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPK---- 314 I GR + D++ V G++LS EIEA L EH+ V E AV+G+ DE G+ + A + K Sbjct: 529 IRGRVD-DVVNVSGHRLSTAEIEAALAEHEGVSEAAVVGITDELTGQAVIAFVSLKDGYL 587 Query: 313 -EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 E+A E P L + ++ P+ P + + + LP+ GK+ Sbjct: 588 SENAVEGDSTHISPDNLRRELILQVRGEIGPFAAPKTVVVVNDLPKTRSGKI 639
>ACS2_ZYGBA (Q96VC7) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 675 Score = 80.1 bits (196), Expect = 6e-15 Identities = 50/160 (31%), Positives = 83/160 (51%), Gaps = 4/160 (2%) Frame = -1 Query: 628 DGVGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNA 461 D G L +KS PS+ + W+ ++++ G++ TGD D DGY+ I GR + Sbjct: 475 DVEGVLAVKSSWPSMARSVWQNHHRYVDTYLKPYPGYYFTGDGAGRDHDGYYWIRGRVD- 533 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D++ V G++LS EIEA L HD V E AV+G+ DE G+ + A + K+ + + ++S Sbjct: 534 DVVNVSGHRLSTAEIEASLTNHDNVSESAVVGIADELTGQSVIAFVSLKDGS---SRESS 590 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L + ++ P+ P + L LP+ GK+ Sbjct: 591 AVVAMRRELVLQVRGEIGPFAAPKCVILVKDLPKTRSGKI 630
>GRSB_BREBE (P0C064) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4449 Score = 79.3 bits (194), Expect = 1e-14 Identities = 55/161 (34%), Positives = 80/161 (49%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGELCI L + Y +PE+TA+ F+ F +KTGD DG +GR + Sbjct: 3922 VGELCIGGQGLARGYLNKPELTADKFVVNPFVPGERMYKTGDLAKWRSDGMIEYVGRVDE 3981 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + KV GY++ EIE+ +LE++ + E V+ A +++CA IV +ED Sbjct: 3982 QV-KVRGYRIELGEIESAILEYEKIKEAVVIVSEHTASEQMLCAYIVGEED--------- 4031 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 LTL+ L S+ L Y IP DS+P GKV+ Sbjct: 4032 --VLTLD-LRSYLAKLLPSYMIPNYFIQLDSIPLTPNGKVD 4069 Score = 69.3 bits (168), Expect = 1e-11 Identities = 44/160 (27%), Positives = 74/160 (46%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELC+ + + Y +P +T E F+ F ++TGD DG LGR + Sbjct: 1840 GELCVGGDGVARGYMNQPALTEEKFVPNPFAPGERMYRTGDLARWLPDGTIEYLGRIDQQ 1899 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ GY++ EIE +L++H V E ++ + D + +CA VP+E+ Sbjct: 1900 V-KIRGYRIEPGEIETLLVKHKKVKESVIMVVEDNNGQKALCAYYVPEEE---------- 1948 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +T+ L + +L Y +P + +P GKVN Sbjct: 1949 --VTVSELREYIAKELPVYMVPAYFVQIEQMPLTQNGKVN 1986 Score = 66.2 bits (160), Expect = 1e-10 Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 +GELCI + + Y RP++TAE F+ F ++TGD DG LGR + Sbjct: 2884 IGELCIGGAGVARGYLNRPDLTAEKFVPNPFVPGEKLYRTGDLARWMPDGNVEFLGRNDH 2943 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ G ++ EIEA L +HD++ E V+ D + +CA +V + + Sbjct: 2944 QV-KIRGIRIELGEIEAQLRKHDSIKEATVIAREDHMKEKYLCAYMVTEGE--------- 2993 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + L ++ L IP+ +++P A GK++ Sbjct: 2994 ---VNVAELRAYLATDLPAAMIPSYFVSLEAMPLTANGKID 3031 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/161 (28%), Positives = 70/161 (43%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGEL I ++ + Y E+TAE F F ++TGD DG LGR + Sbjct: 804 VGELYISGANVGRGYLNNQELTAEKFFADPFRPNERMYRTGDLARWLPDGNIEFLGRADH 863 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ G+++ EIEA LL V E V+ D+ G+ +CA +V + + + Sbjct: 864 QV-KIRGHRIELGEIEAQLLNCKGVKEAVVIDKADDKGGKYLCAYVVMEVEVND------ 916 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + L Y IP+ D LP GK++ Sbjct: 917 ------SELREYLGKALPDYMIPSFFVPLDQLPLTPNGKID 951
>LUCI_LUCLA (Q01158) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 79.3 bits (194), Expect = 1e-14 Identities = 45/126 (35%), Positives = 71/126 (56%), Gaps = 2/126 (1%) Frame = -1 Query: 691 SVNLXPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 518 S + P +AK+I D +T + GE+C+K P L K Y PE T E + G+ TG Sbjct: 364 SGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWLHTG 423 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D DE+ +F I+ R + ++K GY++ E+E+VLL+H + + V G+PD GE+ Sbjct: 424 DIGYYDEEKHFFIVDRLKS-LIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAGEL 482 Query: 337 ICAIIV 320 A++V Sbjct: 483 PGAVVV 488
>GRSB_ANEMI (P0C063) Gramicidin S synthetase 2 (Gramicidin S synthetase II)| [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine Length = 4450 Score = 79.3 bits (194), Expect = 1e-14 Identities = 55/161 (34%), Positives = 80/161 (49%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGELCI L + Y +PE+TA+ F+ F +KTGD DG +GR + Sbjct: 3923 VGELCIGGQGLARGYLNKPELTADKFVVNPFVPGERMYKTGDLAKWRSDGMIEYVGRVDE 3982 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + KV GY++ EIE+ +LE++ + E V+ A +++CA IV +ED Sbjct: 3983 QV-KVRGYRIELGEIESAILEYEKIKEAVVMVSEHTASEQMLCAYIVGEED--------- 4032 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 LTL+ L S+ L Y IP DS+P GKV+ Sbjct: 4033 --VLTLD-LRSYLAKLLPSYMIPNYFIQLDSIPLTPNGKVD 4070 Score = 69.3 bits (168), Expect = 1e-11 Identities = 44/160 (27%), Positives = 74/160 (46%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELC+ + + Y +P +T E F+ F ++TGD DG LGR + Sbjct: 1840 GELCVGGDGVARGYMNQPALTEEKFVPNPFAPGERMYRTGDLARWLPDGTIEYLGRIDQQ 1899 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ GY++ EIE +L++H V E ++ + D + +CA VP+E+ Sbjct: 1900 V-KIRGYRIEPGEIETLLVKHKKVKESVIMVVEDNNGQKALCAYYVPEEE---------- 1948 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +T+ L + +L Y +P + +P GKVN Sbjct: 1949 --VTVSELREYIAKELPVYMVPAYFVQIEQMPLTQNGKVN 1986 Score = 67.0 bits (162), Expect = 6e-11 Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 16/153 (10%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 +GELCI + + Y RP++TAE F+ F ++TGD DG LGR + Sbjct: 2886 IGELCIGGAGVARGYLNRPDLTAEKFVPNPFVPGEKLYRTGDLARWMPDGNVEFLGRNDH 2945 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED--------- 308 + K+ G ++ EIEA L +HD++ E V+ D + +CA +V + + Sbjct: 2946 QV-KIRGIRIELGEIEAQLRKHDSIKEATVIAREDHMKEKYLCAYMVTEGEVNVAELRAY 3004 Query: 307 -ARERAEQASKPALTLEALTSWSKDKLAPYKIP 212 A +RA ++LEA+ + K+ +P Sbjct: 3005 LANDRAAMIPSYFVSLEAMPLTANGKIDKRSLP 3037 Score = 58.5 bits (140), Expect = 2e-08 Identities = 46/161 (28%), Positives = 70/161 (43%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGEL I ++ + Y E+TAE F F ++TGD DG LGR + Sbjct: 804 VGELYISGANVGRGYLNNQELTAEKFFADPFRPNERMYRTGDLARWLPDGNIEFLGRADH 863 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ G+++ EIEA LL V E V+ D+ G+ +CA +V + + + Sbjct: 864 QV-KIRGHRIELGEIEAQLLNCKGVKEAVVIDKADDKGGKYLCAYVVMEVEVND------ 916 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + L Y IP+ D LP GK++ Sbjct: 917 ------SELREYLGKALPDYMIPSFFVPLDQLPLTPNGKID 951
>LUCI_LUCCR (P13129) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 548 Score = 79.0 bits (193), Expect = 1e-14 Identities = 44/126 (34%), Positives = 72/126 (57%), Gaps = 2/126 (1%) Frame = -1 Query: 691 SVNLXPRVEAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 518 S + P +AK+I D ++ + GE+C+K P L K Y PE T E + G+ TG Sbjct: 364 SGKVVPLFKAKVIDLDTKKSLGPNRRGEVCVKGPMLMKGYVNNPEATKELIDEEGWLHTG 423 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D DE+ +F I+ R + ++K GY++ E+E+VLL+H ++ + V G+PD GE+ Sbjct: 424 DIGYYDEEKHFFIVDRLKS-LIKYKGYQVPPAELESVLLQHPSIFDAGVAGVPDPVAGEL 482 Query: 337 ICAIIV 320 A++V Sbjct: 483 PGAVVV 488
>ACSA_PYRAE (O93730) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 79.0 bits (193), Expect = 1e-14 Identities = 53/177 (29%), Positives = 83/177 (46%), Gaps = 5/177 (2%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDT 512 P E ++ ++G GV G L IK P + W PE +++ G F GD Sbjct: 459 PGFEVDVVDENGNPAPPGVKGYLVIKKPWPGMLHGIWGDPERYIKTYWSRFPGMFYAGDY 518 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 332 D+DGY +LGR + +++KV G++L E+E+ L+ H V E AV+G+PD GEV Sbjct: 519 AIKDKDGYIWVLGRAD-EVIKVAGHRLGTYELESALISHPAVAESAVVGVPDAIKGEVPI 577 Query: 331 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A +V K+ E + L + + P P ++ LP+ GK+ Sbjct: 578 AFVVLKQGVAPSDELRKE-------LREHVRRTIGPIAEPAQIFFVTKLPKTRSGKI 627
>ACSA_COPCI (O13440) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 79.0 bits (193), Expect = 1e-14 Identities = 45/125 (36%), Positives = 70/125 (56%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G+F TGD DEDGY I GR + D++ V G++LS EIE+ L+ H V E AV+G D Sbjct: 502 GYFYTGDGAARDEDGYIWIKGRVD-DVINVSGHRLSTAEIESALITHTGVAETAVIGTAD 560 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 E G+ + A + K + + AE ++ L+ E + K + P+ P R+++ LP+ Sbjct: 561 ELTGQAVYAFVTLKPEFKFDAE--NEAGLSKELILQVRK-IIGPFAAPKRIYIVSDLPKT 617 Query: 175 AMGKV 161 GK+ Sbjct: 618 RSGKI 622
>LGRC_BREPA (Q70LM5) Linear gramicidin synthetase subunit C [Includes:| ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent D-valine adenylase (D-ValA) (D-valine activase); Valine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent tr Length = 7756 Score = 78.6 bits (192), Expect = 2e-14 Identities = 53/162 (32%), Positives = 80/162 (49%), Gaps = 8/162 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTN 464 GEL I SL + Y+KRP++T E F+D F ++TGD V DG +GR++ Sbjct: 7032 GELYIAGSSLARGYYKRPDLTQERFVDNPFTANRGAKMYRTGDLVRYLPDGQIEFIGRSD 7091 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 D + + G+++ EIE+VL +H V E VL D + + A +V ED E+A+ Sbjct: 7092 -DQVSIRGFRVELGEIESVLYQHPAVKEAIVLAREDMPGVKRLAAYVVVAEDDAEQADD- 7149 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + K+KL Y +P +LP GKV+ Sbjct: 7150 ---------LRGYLKEKLPEYMVPAAFVTLKALPLTPNGKVD 7182 Score = 74.7 bits (182), Expect = 3e-13 Identities = 52/161 (32%), Positives = 77/161 (47%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGDTVTVDEDGYFIILGRTNA 461 GEL I L + YW RPE+TAE FI F ++TGD V DG LGR + Sbjct: 3393 GELYIGGKGLARGYWNRPELTAERFIAHPFGAKGERLYRTGDLVRYLPDGNLEFLGRIDT 3452 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ GY++ EIE+ L +H + E V+ A+ + + A +V +A+ AE+ Sbjct: 3453 QV-KIRGYRIELGEIESALSQHPAIQEAVVI-----AWEQRLAAYMVAAGEAQPAAEE-- 3504 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + K+ L Y IP D++P GKV+ Sbjct: 3505 --------LARYLKETLPDYMIPAGFVFMDAIPLTVNGKVD 3537 Score = 66.2 bits (160), Expect = 1e-10 Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 8/162 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTN 464 GEL I L Y PE+TAE F+D F ++TGD V DG +GR + Sbjct: 1872 GELYIGGDGLASGYLNNPELTAERFVDNPFDPQKASRLYRTGDLVRYLPDGAIEFIGRID 1931 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 + K+ G+++ EIE LL H V E ++ D + + A +V Q Sbjct: 1932 NQV-KIRGFRIELGEIETALLRHPAVQEAFLMVREDAPGDKRLAAYLV------FAGGQT 1984 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +P + S+ KDKL Y IP+ DS P GKV+ Sbjct: 1985 VEPV----EMRSYLKDKLPEYMIPSAFVQMDSFPLTPNGKVD 2022 Score = 65.5 bits (158), Expect = 2e-10 Identities = 48/163 (29%), Positives = 77/163 (47%), Gaps = 9/163 (5%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTN 464 GEL I L Y E+TAE F++ F ++TGD V +G +GR + Sbjct: 807 GELYIGGDGLALGYLNNAELTAERFVENPFDPQKGSRLYRTGDLVRYLPNGTIEFIGRID 866 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII-VPKEDARERAEQ 287 + K+ G+++ E+EA L H V E V+ ++ + + A + V K+DA E A+ Sbjct: 867 NQV-KIRGFRIELGEVEAALALHPEVSETVVMARENDRGEKHLTAYVTVAKDDAPEVAD- 924 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L +W K KL Y +P+ D++P A GK++ Sbjct: 925 ----------LQAWLKTKLPEYMVPSAYVFLDAMPLTANGKID 957 Score = 64.3 bits (155), Expect = 4e-10 Identities = 48/161 (29%), Positives = 74/161 (45%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFI-------DGGFFKTGDTVTVDEDGYFIILGRTNA 461 GEL I + + YW RPE+TAE FI D ++TGD V E+G LGR + Sbjct: 5972 GELYIGGKGVARGYWNRPELTAERFIADPFGQADERLYRTGDLVRYLENGELEFLGRID- 6030 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D +K+ GY++ EIE L +H V V+ + A + + A +V ++ ++A Sbjct: 6031 DQVKIRGYRIELGEIENALRQHPAVQNVVVIARQEGAGDKRLAAYLVAA--TGQQPDEAE 6088 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + K L Y +P + +P GKV+ Sbjct: 6089 --------LVRYLKSTLPEYMVPAGYVWLEKIPLTVNGKVD 6121 Score = 63.9 bits (154), Expect = 5e-10 Identities = 51/162 (31%), Positives = 71/162 (43%), Gaps = 8/162 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTN 464 GEL I SL + Y RP++T E FI + +KTGD V DG +GR + Sbjct: 4448 GELYIAGDSLARGYLHRPDLTRERFIANPYGQKAGARMYKTGDLVRYLPDGNIEFIGRAD 4507 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 D + + G+++ EIE L H V E VL D + + A IV +E +A QA Sbjct: 4508 -DQVSIRGFRVELGEIETALYSHPAVKETIVLVREDMPGMKRLVAYIVQREGQEGQAVQA 4566 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 S+ K+ L Y +P LP GKV+ Sbjct: 4567 GD-------FRSYLKELLPEYMVPAAFVFMADLPLTPNGKVD 4601
>ACSA_EMENI (P16928) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 670 Score = 78.6 bits (192), Expect = 2e-14 Identities = 52/160 (32%), Positives = 83/160 (51%), Gaps = 4/160 (2%) Frame = -1 Query: 628 DGVGELCIKSP--SLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTNA 461 D G L K P S+ + W + ++++ G++ TGD D +GY+ I GR + Sbjct: 478 DVEGVLAFKQPWPSMARTVWGAHKRYMDTYLQVYKGYYFTGDGAGRDHEGYYWIRGRVD- 536 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D++ V G++LS EIEA L+EH V E AV+G+ DE G+ + A + KE E +Q Sbjct: 537 DVVNVSGHRLSTAEIEAALIEHPMVAEAAVVGIADELTGQAVNAFVSLKE-GNETNDQVR 595 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K L L+ + + P+ P + + D LP+ GK+ Sbjct: 596 KD-LILQV-----RKSIGPFAAPKAVFVVDDLPKTRSGKI 629
>4CL2_ORYSA (Q42982) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 569 Score = 78.2 bits (191), Expect = 2e-14 Identities = 44/153 (28%), Positives = 82/153 (53%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ P + K Y PE TA + G+ TGD VD+D I+ R +++K G Sbjct: 416 GEICIRGPQIMKGYLNDPEATAATIDVEGWLHTGDIGYVDDDDEVFIVDRVK-ELIKFKG 474 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 +++ E+E++L+ H ++ + AV+ D+ GEV A +V +A+ +T E Sbjct: 475 FQVPPAELESLLIAHPSIADAAVVPQKDDVAGEVPVAFVV----------RAADSDITEE 524 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ + ++ YK ++H ++P++A GK+ Sbjct: 525 SIKEFISKQVVFYKRLHKVHFIHAIPKSASGKI 557
>ACSA_MYCTU (O69635) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 78.2 bits (191), Expect = 2e-14 Identities = 60/185 (32%), Positives = 88/185 (47%), Gaps = 13/185 (7%) Frame = -1 Query: 676 PRVEAKIIMDDG------TETKDGV-GELCIKSP--SLFKEYWKRPEVTAES----FIDG 536 P + AKI+ D G TE V G L + P S+ + W P S F D Sbjct: 442 PGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDK 501 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G++ GD +D DG +LGR + D+M V G+++S E+E+ L+ H V E AV+G+ D Sbjct: 502 GYYFAGDGARIDPDGAIWVLGRID-DVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTD 560 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 E + ICA +V RA A T E L + ++P P +H+ LP+ Sbjct: 561 ETTTQAICAFVV------LRANYAPHDR-TAEELRTEVARVISPIARPRDVHVVPELPKT 613 Query: 175 AMGKV 161 GK+ Sbjct: 614 RSGKI 618
>ACSA_MYCBO (P59871) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 78.2 bits (191), Expect = 2e-14 Identities = 60/185 (32%), Positives = 88/185 (47%), Gaps = 13/185 (7%) Frame = -1 Query: 676 PRVEAKIIMDDG------TETKDGV-GELCIKSP--SLFKEYWKRPEVTAES----FIDG 536 P + AKI+ D G TE V G L + P S+ + W P S F D Sbjct: 442 PGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDK 501 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G++ GD +D DG +LGR + D+M V G+++S E+E+ L+ H V E AV+G+ D Sbjct: 502 GYYFAGDGARIDPDGAIWVLGRID-DVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTD 560 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 E + ICA +V RA A T E L + ++P P +H+ LP+ Sbjct: 561 ETTTQAICAFVV------LRANYAPHDR-TAEELRTEVARVISPIARPRDVHVVPELPKT 613 Query: 175 AMGKV 161 GK+ Sbjct: 614 RSGKI 618
>ACSA_NEUCR (P16929) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 667 Score = 77.8 bits (190), Expect = 3e-14 Identities = 48/160 (30%), Positives = 82/160 (51%), Gaps = 4/160 (2%) Frame = -1 Query: 628 DGVGELCIKSP--SLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTNA 461 D G L K P S+ + W + E+++ G++ TGD D +G++ I GR + Sbjct: 476 DVEGVLAFKQPWPSMARTVWGAHKRYMETYLHVYKGYYFTGDGAARDHEGFYWIRGRVD- 534 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D++ V G++LS EIEA L+EH ++ E AV+G+ DE G+ + A + KE + A Sbjct: 535 DVVNVSGHRLSTAEIEAALIEHHSIAEAAVVGVADELTGQAVNAFVAVKEGT--QINDAL 592 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + L+ S + P+ P +++ LP+ GK+ Sbjct: 593 RKEFVLQVRRS-----IGPFAAPKAIYIVPDLPKTRSGKI 627
>LUCI_PHOPY (P08659) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 550 Score = 77.4 bits (189), Expect = 4e-14 Identities = 43/122 (35%), Positives = 69/122 (56%), Gaps = 3/122 (2%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVT 506 P EAK++ D +T GV GELC++ P + Y PE T G+ +GD Sbjct: 367 PFFEAKVVDLDTGKTL-GVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAY 425 Query: 505 VDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI 326 DED +F I+ R + ++K GY+++ E+E++LL+H + + V GLPD+ GE+ A+ Sbjct: 426 WDEDEHFFIVDRLKS-LIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAV 484 Query: 325 IV 320 +V Sbjct: 485 VV 486
>LGRD_BREPA (Q70LM4) Linear gramicidin synthetase subunit D [Includes:| ATP-dependent tryptophan adenylase (TrpA) (Tryptophan activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-Leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-d Length = 5085 Score = 77.4 bits (189), Expect = 4e-14 Identities = 53/161 (32%), Positives = 80/161 (49%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGDTVTVDEDGYFIILGRTNA 461 GEL I L + YW RPE+TAESFI F ++TGD V +DG LGR + Sbjct: 793 GELYIGGKGLARGYWNRPELTAESFIPHPFGTAGERLYRTGDLVRYRQDGNLEFLGRIDH 852 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ GY++ EIE + +H V E V+ ++A + + A +V A +A Sbjct: 853 QV-KIRGYRIELGEIENAIRQHPAVQEAVVIAREEKAGDKRLAAYLV-------AAGKAQ 904 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 PA E + + K+ L Y +P + D++P GKV+ Sbjct: 905 PPA---EEIALFLKETLPEYMVPAGVVWLDAIPLTVNGKVD 942 Score = 73.2 bits (178), Expect = 8e-13 Identities = 49/161 (30%), Positives = 75/161 (46%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGDTVTVDEDGYFIILGRTNA 461 GEL I L + YW RPE+TAE F+ F ++TGD V DG LGR + Sbjct: 3377 GELYIGGECLARGYWNRPELTAERFVANPFGQPGERLYRTGDLVRYLPDGNVDYLGRFD- 3435 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D +K+ GY++ EI L +H + E VL + + A + A+ Sbjct: 3436 DQVKIRGYRIELGEIAEALRQHAAIREAVVLAREVRPGDKRLAAYLT----------SAA 3485 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + L+++ + W K+KL Y +P ++P N GKV+ Sbjct: 3486 EQELSVDEIKQWLKEKLPDYMVPASYTWLPAIPLNVNGKVD 3526 Score = 68.9 bits (167), Expect = 1e-11 Identities = 49/161 (30%), Positives = 74/161 (45%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGDTVTVDEDGYFIILGRTNA 461 GEL + L + Y RP++TAE F+ F ++TGD V DG +GR + Sbjct: 4432 GELYLSGSGLARGYLHRPDLTAERFVQNPFREPGARMYRTGDLVRYLPDGNLQFVGRVDY 4491 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ GY++ EIE+VL V E +L D + + A IV + D + Sbjct: 4492 QV-KIRGYRIELGEIESVLNRFPGVKEVVLLAREDREGDKCLVAYIVFEADCTSK----- 4545 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + L + DKL Y IP + DSLP+ GK++ Sbjct: 4546 -----IHDLNHFLADKLPAYMIPQHYMILDSLPKTPNGKLD 4581 Score = 49.7 bits (117), Expect = 9e-06 Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 8/162 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTN 464 GEL I SL + Y RP++T E F+ F ++TGD V DG +GR + Sbjct: 1853 GELYIGGSSLARGYLNRPDLTQERFVAHPFTEKAGARLYRTGDLVRSLPDGSIEFIGRAD 1912 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 D + G+++ E+E ++ V E V D+ + + A +V +E A Sbjct: 1913 -DQTSIRGFRVELGEVETAIVALPAVKEAVVTVCTDKQGTKRLAAYLVLEEGA------- 1964 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 AL + K+ L Y +P LP GKV+ Sbjct: 1965 ---ALATGDIRKALKETLPDYMVPAFFTQLAYLPLTPNGKVD 2003
>ACSA_LEPIN (Q8EYG2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 77.0 bits (188), Expect = 5e-14 Identities = 53/177 (29%), Positives = 90/177 (50%), Gaps = 7/177 (3%) Frame = -1 Query: 670 VEAKIIMDDGTETKDG---VGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDT 512 V+ ++ +DG E D G LCIK P S+ + + P+ E++ G++ TGD Sbjct: 453 VQPVLVDNDGKEITDKGEVSGNLCIKGPWPSMMRGVYGDPKRFFETYFSQFKGYYFTGDG 512 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 332 D+DGYF I GR + D++ V G+++ + E+E+ L+E+ +V E AV+G P + G+ I Sbjct: 513 ARRDKDGYFWITGRVD-DVINVSGHRIGSAEVESALVENKSVAEAAVVGFPHDIKGQGIY 571 Query: 331 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A + KE + L E +++ K + P +H LP+ GK+ Sbjct: 572 AYVTVKEGV------TTNDVLKKELISTVEK-MIGKIARPDVIHWAPGLPKTRSGKI 621
>ACSA_LEPIC (Q72LY9) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 661 Score = 77.0 bits (188), Expect = 5e-14 Identities = 53/177 (29%), Positives = 90/177 (50%), Gaps = 7/177 (3%) Frame = -1 Query: 670 VEAKIIMDDGTETKDG---VGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDT 512 V+ ++ +DG E D G LCIK P S+ + + P+ E++ G++ TGD Sbjct: 453 VQPVLVDNDGKEITDKGEVSGNLCIKGPWPSMMRGVYGDPKRFFETYFSQFKGYYFTGDG 512 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 332 D+DGYF I GR + D++ V G+++ + E+E+ L+E+ +V E AV+G P + G+ I Sbjct: 513 ARRDKDGYFWITGRVD-DVINVSGHRIGSAEVESALVENKSVAEAAVVGFPHDIKGQGIY 571 Query: 331 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A + KE + L E +++ K + P +H LP+ GK+ Sbjct: 572 AYVTVKEGV------TTNDVLKKELISTVEK-MIGKIARPDVIHWAPGLPKTRSGKI 621
>4CL1_ARATH (Q42524) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1) (At4CL1)| (4-coumaroyl-CoA synthase 1) Length = 561 Score = 77.0 bits (188), Expect = 5e-14 Identities = 46/171 (26%), Positives = 89/171 (52%), Gaps = 2/171 (1%) Frame = -1 Query: 667 EAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDED 494 E KI+ D ++ ++ GE+CI+ + K Y P TAE+ G+ TGD +D+D Sbjct: 389 EMKIVDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDD 448 Query: 493 GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPK 314 I+ R +++K G++++ E+EA+L+ H + + AV+ + +EA GEV A +V Sbjct: 449 DELFIVDRLK-ELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKS 507 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 +D+ L+ + + + ++ YK ++ +S+P+ GK+ Sbjct: 508 KDSE----------LSEDDVKQFVSKQVVFYKRINKVFFTESIPKAPSGKI 548
>BACA_BACLI (O68006) Bacitracin synthetase 1 (BA1) [Includes: ATP-dependent| isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent cysteine adenylase (CysA) (Cysteine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase); ATP-depe Length = 5255 Score = 77.0 bits (188), Expect = 5e-14 Identities = 52/160 (32%), Positives = 75/160 (46%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELCI + + Y RPE+TAE F+D F +KTGD DG LGR + Sbjct: 3492 GELCIAGEGVARGYVNRPELTAEKFVDHPFEPGKKMYKTGDLAMWLPDGQIEFLGRADHQ 3551 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ GY++ E+E LL H+ + E AV+ D+ +CA I AS Sbjct: 3552 V-KIRGYRIELGEVEQQLLTHEKIKEAAVIAGKDQNGNSYLCAYI------------ASD 3598 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + + + ++ Y IP+ D LPR GKV+ Sbjct: 3599 KELPAADVRQFLEREMPDYMIPSYFVKLDRLPRTPSGKVD 3638 Score = 74.7 bits (182), Expect = 3e-13 Identities = 50/160 (31%), Positives = 74/160 (46%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELCI L + Y RPE+T E FI F ++TGD + DG LGR + Sbjct: 2451 GELCIAGEGLARGYVNRPELTREKFIGNPFVPGERMYRTGDLAKMLPDGNIQFLGRVDQQ 2510 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ GY++ EIE LL+++ + E AV+ D + +CA + K++ Sbjct: 2511 V-KIRGYRIEPGEIENRLLKYEKIEEAAVIAREDGDHDPYLCAYVTVKKEVEP------- 2562 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 E + ++ K L Y IP D LP GKV+ Sbjct: 2563 -----EKIRAFLKKSLPDYMIPQYFVQLDGLPLTVNGKVD 2597 Score = 70.1 bits (170), Expect = 7e-12 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 8/175 (4%) Frame = -1 Query: 658 IIMDD-GTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTV 503 +IMD+ G GV GELCI L K Y R E+TAE FI F +KTGD Sbjct: 4986 LIMDEAGKLLPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERLYKTGDLAKW 5045 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 DG +GR + + K+ G+++ EIE+ L H+ + E V DE ICA I Sbjct: 5046 LPDGNIEFIGRIDHQV-KIRGFRIELGEIESRLEMHEDINETIVTVREDEESRPYICAYI 5104 Query: 322 VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + ++L+ L + +KL Y IP D LP GKV+ Sbjct: 5105 TANRE------------ISLDELKGFLGEKLPDYMIPAYFVKMDKLPLTKNGKVD 5147 Score = 70.1 bits (170), Expect = 7e-12 Identities = 58/175 (33%), Positives = 79/175 (45%), Gaps = 8/175 (4%) Frame = -1 Query: 658 IIMDD-GTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTV 503 +IMD+ G GV GELCI L K Y R E+TAE FI F +KTGD Sbjct: 359 LIMDEAGKLVPIGVPGELCIAGDGLSKGYLNREELTAEKFIPHPFIPGERLYKTGDLAKW 418 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 DG +GR + + K+ G+++ EIE+ L H+ + E V DE ICA I Sbjct: 419 LPDGNIEFIGRIDHQV-KIRGFRIELGEIESRLEMHEDINETIVTVREDEESRPYICAYI 477 Query: 322 VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + ++L+ L + +KL Y IP D LP GKV+ Sbjct: 478 TANRE------------ISLDELKGFLGEKLPEYMIPAYFVKLDKLPLTKNGKVD 520 Score = 53.5 bits (127), Expect = 6e-07 Identities = 45/163 (27%), Positives = 69/163 (42%), Gaps = 9/163 (5%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFID----GGFFKTGDTVTVDEDGYFIILGRTNADIM 452 GEL I + Y E T SFI G +KTGD + EDGY LGR ++ + Sbjct: 1413 GELYIGGAGVASGYIHDQEKTEHSFIQHQELGYIYKTGDYGVLKEDGYVEFLGRKDSQV- 1471 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGL--PD---EAYGEVICAIIVPKEDARERAEQ 287 K+ GY++ EIE L+ H + + +V+ PD Y V+ + + D +E ++ Sbjct: 1472 KIRGYRVEMGEIENTLVSHQEITKASVIDYTSPDGIKNLYAFVVAENAISQLDVKEFLQK 1531 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L Y IP + + +P GKV+ Sbjct: 1532 T-----------------LPDYMIPAKFVQIEEIPLTVNGKVD 1557
>TYCC_BREPA (O30409) Tyrocidine synthetase 3 (Tyrocidine synthetase III)| [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Ty Length = 6486 Score = 76.6 bits (187), Expect = 7e-14 Identities = 52/160 (32%), Positives = 80/160 (50%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFID------GGFFKTGDTVTVDEDGYFIILGRTNAD 458 GELCI L + YW+R E+T SF+D G ++TGD V DG+ LGR + Sbjct: 1837 GELCIAGDGLARGYWQREELTKASFVDNPFEPGGTMYRTGDMVRYLPDGHIEYLGRIDHQ 1896 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ G+++ EIEA LL+H+ V V+ D + A +V ++D + AE + Sbjct: 1897 V-KIRGHRIELGEIEATLLQHEAVKAVVVMARQDGKGQNSLYAYVVAEQDI-QTAELRTY 1954 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + TL A Y +P+ + LP +A GKV+ Sbjct: 1955 LSATLPA-----------YMVPSAFVFLEQLPLSANGKVD 1983 Score = 74.3 bits (181), Expect = 4e-13 Identities = 53/162 (32%), Positives = 79/162 (48%), Gaps = 7/162 (4%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGELCI L + Y +PE+TAE F+ F +KTGD V DG +GR + Sbjct: 5995 VGELCIGGAGLARGYLNKPELTAEKFVANPFRPGERMYKTGDLVKWRTDGTIEYIGRADE 6054 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA-YGEVICAIIVPKEDARERAEQA 284 + KV GY++ EIE+ +L + + + V+ D+A G +CA V Sbjct: 6055 QV-KVRGYRIEIGEIESAVLAYQGIDQAVVVARDDDATAGSYLCAYFV------------ 6101 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + A+++ L S +L Y IP+ D LP +A GKV+ Sbjct: 6102 AATAVSVSGLRSHLAKELPAYMIPSYFVELDQLPLSANGKVD 6143 Score = 69.7 bits (169), Expect = 9e-12 Identities = 54/163 (33%), Positives = 79/163 (48%), Gaps = 9/163 (5%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELC+ + + Y +PE+TAE F+ F ++TGD DG LGR + Sbjct: 3910 GELCVGGDGVARGYVNKPELTAEKFVPNPFAPGETMYRTGDLARWLPDGTIEYLGRIDQQ 3969 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE-VICAIIVPKE--DARERAEQ 287 + K+ GY++ EIE VL + V E AV+ + +EA G+ +CA VP++ DA E E Sbjct: 3970 V-KIRGYRIELGEIETVLSQQAQVKE-AVVAVIEEANGQKALCAYFVPEQAVDAAELREA 4027 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 SK +L Y +P + LP A GKV+ Sbjct: 4028 MSK--------------QLPGYMVPAYYVQMEKLPLTANGKVD 4056 Score = 63.2 bits (152), Expect = 8e-10 Identities = 49/160 (30%), Positives = 73/160 (45%), Gaps = 6/160 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 +GE+ I + K Y+ RPE+T E FID F ++TGD DG GR + Sbjct: 799 LGEMYIAGDGVAKGYFNRPELTKEKFIDNPFRPGTKMYRTGDLAKWLPDGNMEYAGRMDY 858 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ G+++ EIE L +H+ V E V+ DE+ V+ A +V S Sbjct: 859 QV-KIRGHRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVLYAYLV------------S 905 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + LT+ L + L Y IP+ +P A GKV Sbjct: 906 ERELTVAELREFLGRTLPSYMIPSFFIRLAEIPLTANGKV 945 Score = 62.4 bits (150), Expect = 1e-09 Identities = 49/161 (30%), Positives = 72/161 (44%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGELCI + + Y RPE+T E F+ F ++TGD DG LGR + Sbjct: 4953 VGELCIGGAGVARGYLNRPELTEEKFVPNPFAPGERLYRTGDLAKWRADGNVEFLGRNDH 5012 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ G ++ EIE L + D + E V+ D + +CA +V A + + A Sbjct: 5013 QV-KIRGVRIELGEIETQLRKLDGITEAVVVAREDRGQEKELCAYVV----ADHKLDTAE 5067 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 A L+ +L IP D+LP A GKV+ Sbjct: 5068 LRANLLK--------ELPQAMIPAYFVTLDALPLTANGKVD 5100 Score = 62.4 bits (150), Expect = 1e-09 Identities = 47/161 (29%), Positives = 67/161 (41%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGE+CI L + YW +P +T E F+ F +KTGD DG +GR + Sbjct: 2874 VGEICIGGRGLARGYWNKPALTEEKFVSHPFAAGERMYKTGDLGKWLPDGTIEYIGRIDE 2933 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + KV GY++ EIE+ LL + + V+ D+ + A E Sbjct: 2934 QV-KVRGYRIEIGEIESALLAAEKLTAAVVVVYEDQLGQSALAAYFTADEQ--------- 2983 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + L S +L Y IP D LP GKV+ Sbjct: 2984 ---LDVTKLWSHLSKRLPSYMIPAHFVQLDQLPLTPNGKVD 3021
>Y3568_PSEAE (P28812) Hypothetical protein PA3568| Length = 628 Score = 76.3 bits (186), Expect = 9e-14 Identities = 43/125 (34%), Positives = 71/125 (56%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G++ TGD +DEDG+ I+GRT+ D++ V G++LS E+E + +H V ECAV+G+ D Sbjct: 472 GYYHTGDGGYLDEDGFVYIMGRTD-DVINVSGHRLSTGEMEERVAQHQAVAECAVIGVRD 530 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 E G V ++V K+DA AEQ + + L ++++ R+ + LP+ Sbjct: 531 ELKGHVPLGLVVLKDDAGIAAEQLQRELVAL------VREQIGALACFQRVVVVKRLPKT 584 Query: 175 AMGKV 161 GK+ Sbjct: 585 RSGKI 589
>4CL1_TOBAC (O24145) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 547 Score = 76.3 bits (186), Expect = 9e-14 Identities = 44/153 (28%), Positives = 80/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y PE T + G+ TGD +DED I+ R +++K G Sbjct: 391 GEICIRGDQIMKGYLNDPEATTRTIDKEGWLHTGDIGFIDEDDELFIVDRLK-ELIKYKG 449 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ EIEA+LL H + + AV+ + DE GEV A +V +++ A+T + Sbjct: 450 FQVAPAEIEALLLNHPNISDAAVVPMKDEQAGEVPVAFVV----------RSNGSAITED 499 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + ++ YK R+ +++P++ GK+ Sbjct: 500 EVKDFISKQVIFYKRVKRVFFVETVPKSPSGKI 532
>ACSA_YERPE (Q8D1G8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 75.9 bits (185), Expect = 1e-13 Identities = 50/145 (34%), Positives = 76/145 (52%) Frame = -1 Query: 595 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEI 416 +LF ++ +R E T S G +F +GD DEDGY+ I GR + D++ V G++L EI Sbjct: 476 TLFGDH-ERFEQTYFSTFKGMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEI 532 Query: 415 EAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKD 236 E+ L+ H + E AV+G+P G+ I A I + P L E + +W + Sbjct: 533 ESALVAHPKIAEAAVVGVPHNIKGQAIYAYITLNHG------EEPTPELYTE-VRNWVRK 585 Query: 235 KLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ P P LH DSLP+ GK+ Sbjct: 586 EIGPLATPDILHWTDSLPKTRSGKI 610
>4CL_PINTA (P41636) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 537 Score = 75.5 bits (184), Expect = 2e-13 Identities = 46/153 (30%), Positives = 81/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ P + K Y PE TA + + G+ TGD +D+D I+ R +I+K G Sbjct: 386 GEICIRGPEIMKGYINDPESTAATIDEEGWLHTGDVEYIDDDEEIFIVDRVK-EIIKYKG 444 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+L+ H ++ + AV+ E GEV A +V + E +EQ K + + Sbjct: 445 FQVAPAELEALLVAHPSIADAAVVPQKHEEAGEVPVAFVV---KSSEISEQEIKEFVAKQ 501 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + YK R++ D++P++ GK+ Sbjct: 502 VIF---------YKKIHRVYFVDAIPKSPSGKI 525
>4CL2_TOBAC (O24146) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 542 Score = 75.5 bits (184), Expect = 2e-13 Identities = 43/153 (28%), Positives = 80/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y PE TA + G+ TGD +D+D I+ R +++K G Sbjct: 386 GEICIRGDQIMKGYLNDPEATARTIDKEGWLYTGDIGYIDDDDELFIVDRLK-ELIKYKG 444 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+LL H + + AV+ + DE GEV A +V +++ +T + Sbjct: 445 FQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVV----------RSNGSTITED 494 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + ++ YK R+ D++P++ GK+ Sbjct: 495 EVKDFISKQVIFYKRIKRVFFVDAIPKSPSGKI 527
>ACSA_VIBVY (Q7MGU3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 75.1 bits (183), Expect = 2e-13 Identities = 39/125 (31%), Positives = 64/125 (51%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD DEDGY+ I GR + D++ V G+++ EIE+ L+ H + E A++G+P Sbjct: 495 GMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAHPKIAEAAIVGIPH 553 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ I A + AE + + W + ++ P P LH D+LP+ Sbjct: 554 DIKGQAIYAYVTLNAGEYPTAELHKE-------VKDWVRKEIGPIATPDVLHWTDALPKT 606 Query: 175 AMGKV 161 GK+ Sbjct: 607 RSGKI 611
>ACSA_VIBVU (Q8DCZ9) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 75.1 bits (183), Expect = 2e-13 Identities = 39/125 (31%), Positives = 64/125 (51%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD DEDGY+ I GR + D++ V G+++ EIE+ L+ H + E A++G+P Sbjct: 495 GMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAHPKIAEAAIVGIPH 553 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ I A + AE + + W + ++ P P LH D+LP+ Sbjct: 554 DIKGQAIYAYVTLNAGEYPTAELHKE-------VKDWVRKEIGPIATPDVLHWTDALPKT 606 Query: 175 AMGKV 161 GK+ Sbjct: 607 RSGKI 611
>ACSA_VIBPA (Q87KU7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 75.1 bits (183), Expect = 2e-13 Identities = 40/125 (32%), Positives = 64/125 (51%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + T D DEDGY+ I GR + D++ V G+++ EIE+ L+ H + E A++G+P Sbjct: 495 GMYFTSDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAHHKIAEAAIVGIPH 553 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ I A I + AE + + W + ++ P P LH DSLP+ Sbjct: 554 DIKGQAIYAYITLNDGEFPSAELHKE-------VKDWVRKEIGPIATPDVLHWTDSLPKT 606 Query: 175 AMGKV 161 GK+ Sbjct: 607 RSGKI 611
>ALKK_PSEOL (Q00594) Medium-chain-fatty-acid--CoA ligase (EC 6.2.1.-)| (Medium-chain acyl-CoA synthetase) Length = 546 Score = 74.7 bits (182), Expect = 3e-13 Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 3/173 (1%) Frame = -1 Query: 670 VEAKIIMDDGTET-KDG--VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 VE KI+ D+G +DG G L + + K+Y+ S + G+F TGD T+D Sbjct: 366 VELKIVNDEGIRLPEDGRSKGNLMARGHWVIKDYFHSDP---GSTLSDGWFSTGDVATID 422 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 DG+ I R DI+K GG +S +E+E++ + H +++ AV+ E + E I V Sbjct: 423 SDGFMTICDRAK-DIIKSGGEWISTVELESIAIAHPHIVDAAVIAARHEKWDERPLLIAV 481 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ LT + ++ DK+A ++IP + LPRN GK+ Sbjct: 482 KSPNSE----------LTSGEVCNYFADKVARWQIPDAAIFVEELPRNGTGKI 524
>ACS1_CANAL (O94049) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 675 Score = 74.7 bits (182), Expect = 3e-13 Identities = 51/162 (31%), Positives = 82/162 (50%), Gaps = 6/162 (3%) Frame = -1 Query: 628 DGVGELCIKS--PSLFKEYWKRPEVTAESFID--GGFFKTGDTVTVDEDGYFIILGRTNA 461 D G L IKS PS+ + + ++++ ++ +GD D DG++ ILGR + Sbjct: 481 DVEGVLAIKSAWPSITRGIYNDYNRFIDTYLAPYANYYFSGDGAARDRDGFYWILGRVD- 539 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED--ARERAEQ 287 D++ V G++LS EIEA L+EH V E AV+G DE G+ + A + K+D E E Sbjct: 540 DVVNVSGHRLSTAEIEAALIEHPIVGESAVVGYADELTGQAVAAYVSLKKDKAVGEDVEN 599 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K + + ++ P+ P + L D LP+ GK+ Sbjct: 600 IKKEMILT------VRKEIGPFAAPKMILLVDDLPKTRSGKI 635
>ACSA_STRCO (Q9X928) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 74.3 bits (181), Expect = 4e-13 Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 6/191 (3%) Frame = -1 Query: 715 MVHGKKVQSVNLXPRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF 545 + H K + P + A ++ D+ E +G G + + PS+ + W + +++ Sbjct: 430 VTHAKPGSAQRPLPGISATVVDDEANEVPNGGGGYLVLTEPWPSMLRTIWGDDQRFIDTY 489 Query: 544 ---IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECA 374 +G +F GD D+DG +LGR + D+M V G+ +S E+E+ L+ H +V E A Sbjct: 490 WSRFEGKYF-AGDGAKKDDDGDIWLLGRVD-DVMLVSGHNISTTEVESALVSHPSVAEAA 547 Query: 373 VLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLW 194 V+G DE G+ I A ++ + E + ++ L + L P P R+ Sbjct: 548 VVGATDETTGQAIVAFVILRGTTAESEDLVAE-------LRNHVGATLGPIAKPKRILPV 600 Query: 193 DSLPRNAMGKV 161 LP+ GK+ Sbjct: 601 SELPKTRSGKI 611
>ACSA_SYNY3 (Q55404) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 653 Score = 74.3 bits (181), Expect = 4e-13 Identities = 56/186 (30%), Positives = 88/186 (47%), Gaps = 14/186 (7%) Frame = -1 Query: 676 PRVEAKIIMDDGTETK-DGVGELCIKSP--SLFKE-----------YWKRPEVTAESFID 539 P + A+I+ DG + D G L IK P S+ ++ YW+ + ++ Sbjct: 447 PGIVAEIVDLDGNPVESDQGGFLVIKQPWPSMIRDVYGDTDRFRHTYWEHIQPKEGQYL- 505 Query: 538 GGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 359 + GD D+DGYF ++GR + D++ V G++L +EIE+ L+ H V E AV+G P Sbjct: 506 ---YFAGDGARRDKDGYFWVMGRVD-DVINVSGHRLGTMEIESALVSHPLVAEAAVVGRP 561 Query: 358 DEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 179 DE GE I A V E E +E+ K L +++ P + D LP+ Sbjct: 562 DELTGEAIFA-FVSLEGNAEPSEELKKD------LVKHVTEEIGAIARPAEIRFTDVLPK 614 Query: 178 NAMGKV 161 GK+ Sbjct: 615 TRSGKI 620
>ACSA_SYNEL (Q8DKH2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 74.3 bits (181), Expect = 4e-13 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 1/125 (0%) Frame = -1 Query: 532 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 353 F+ GD DEDGYF ++GR + D++ V G++L +EIE+ L+ H V E AV+G PDE Sbjct: 507 FYFAGDGARRDEDGYFWVMGRVD-DVINVSGHRLGTMEIESALVSHPAVAEAAVVGKPDE 565 Query: 352 AYGEVICAIIVPKEDARERAEQASKPALTL-EALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 GE I A ++ E ++ P+ L + L +++ P + D+LP+ Sbjct: 566 VKGEEIVAFVI--------LEGSATPSDALQQELKQHVVNEIGALARPAEIRFTDALPKT 617 Query: 175 AMGKV 161 GK+ Sbjct: 618 RSGKI 622
>4CL2_PETCR (P14913) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 74.3 bits (181), Expect = 4e-13 Identities = 45/153 (29%), Positives = 79/153 (51%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y PE T + + G+ TGD +D+D I+ R +I+K G Sbjct: 387 GEICIRGDQIMKGYLNDPESTRTTIDEEGWLHTGDIGFIDDDDELFIVDRLK-EIIKYKG 445 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+LL H T+ + AV+ + DE GEV A +V + + T E Sbjct: 446 FQVAPAELEALLLTHPTISDAAVVPMIDEKAGEVPVAFVV----------RTNGFTTTEE 495 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + ++ YK R+ D++P++ GK+ Sbjct: 496 EIKQFVSKQVVFYKRIFRVFFVDAIPKSPSGKI 528
>4CL1_PETCR (P14912) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 544 Score = 74.3 bits (181), Expect = 4e-13 Identities = 45/153 (29%), Positives = 79/153 (51%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y PE T + + G+ TGD +D+D I+ R +I+K G Sbjct: 387 GEICIRGDQIMKGYLNDPESTRTTIDEEGWLHTGDIGFIDDDDELFIVDRLK-EIIKYKG 445 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+LL H T+ + AV+ + DE GEV A +V + + T E Sbjct: 446 FQVAPAELEALLLTHPTISDAAVVPMIDEKAGEVPVAFVV----------RTNGFTTTEE 495 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + ++ YK R+ D++P++ GK+ Sbjct: 496 EIKQFVSKQVVFYKRIFRVFFVDAIPKSPSGKI 528
>ACSA_ECOLI (P27550) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 74.3 bits (181), Expect = 4e-13 Identities = 50/145 (34%), Positives = 77/145 (53%) Frame = -1 Query: 595 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEI 416 +LF ++ +R E T S +F +GD DEDGY+ I GR + D++ V G++L EI Sbjct: 476 TLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEI 532 Query: 415 EAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKD 236 E+ L+ H + E AV+G+P G+ I A + E+ S P L E + +W + Sbjct: 533 ESALVAHPKIAEAAVVGIPHNIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRK 585 Query: 235 KLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ P P LH DSLP+ GK+ Sbjct: 586 EIGPLATPDVLHWTDSLPKTRSGKI 610
>ACSA_ECOL6 (Q8FAY8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 74.3 bits (181), Expect = 4e-13 Identities = 50/145 (34%), Positives = 77/145 (53%) Frame = -1 Query: 595 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEI 416 +LF ++ +R E T S +F +GD DEDGY+ I GR + D++ V G++L EI Sbjct: 476 TLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEI 532 Query: 415 EAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKD 236 E+ L+ H + E AV+G+P G+ I A + E+ S P L E + +W + Sbjct: 533 ESALVAHPKIAEAAVVGIPHNIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRK 585 Query: 235 KLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ P P LH DSLP+ GK+ Sbjct: 586 EIGPLATPDVLHWTDSLPKTRSGKI 610
>4CL_VANPL (O24540) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) Length = 553 Score = 74.3 bits (181), Expect = 4e-13 Identities = 45/153 (29%), Positives = 78/153 (50%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y PE TA + G+ TGD +D+D I+ R +++K G Sbjct: 395 GEICIRGDQIMKGYLNDPEATARTIDKEGWLHTGDIGYIDDDDELFIVDRLK-ELIKYKG 453 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+LL H + + AV+ + DEA GEV A +V K + E K ++ + Sbjct: 454 FQVAPAELEALLLTHPCISDAAVVPMKDEAAGEVPVAFVV-KSNGHNITEDEIKQFISKQ 512 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + YK R+ +++P+ GK+ Sbjct: 513 VIF---------YKRINRVFFVEAIPKAPSGKI 536
>MENE_LACLA (Q9CHK3) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 451 Score = 73.9 bits (180), Expect = 5e-13 Identities = 51/156 (32%), Positives = 77/156 (49%), Gaps = 1/156 (0%) Frame = -1 Query: 625 GVGELCIKSPSLFKEYW-KRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMK 449 GVGE+ +KSP L K Y ++P TA F+TGD +D DG+ +L R DI+ Sbjct: 312 GVGEIWLKSPMLMKAYLGQKPYGTA--------FETGDIGYLDTDGFLYLLNRRK-DIII 362 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 GG + EIE ++ + ECA++ PD +G+V + + Sbjct: 363 SGGENIYPKEIEDLVYSLPEIKECALVAKPDAKWGQVPILFVSGN--------------I 408 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + E L ++ +KLA YK P + D LP+NA GK+ Sbjct: 409 SQEKLENFLTEKLAKYKRPQSITFMDELPKNASGKI 444
>ACSA_SALTY (Q8ZKF6) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 73.9 bits (180), Expect = 5e-13 Identities = 50/145 (34%), Positives = 77/145 (53%) Frame = -1 Query: 595 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEI 416 +LF ++ +R E T S +F +GD DEDGY+ I GR + D++ V G++L EI Sbjct: 476 TLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEI 532 Query: 415 EAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKD 236 E+ L+ H + E AV+G+P G+ I A + E+ S P L E + +W + Sbjct: 533 ESALVAHPKIAEAAVVGIPHAIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRK 585 Query: 235 KLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ P P LH DSLP+ GK+ Sbjct: 586 EIGPLATPDVLHWTDSLPKTRSGKI 610
>ACSA_SALTI (Q8Z1R0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 73.9 bits (180), Expect = 5e-13 Identities = 50/145 (34%), Positives = 77/145 (53%) Frame = -1 Query: 595 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEI 416 +LF ++ +R E T S +F +GD DEDGY+ I GR + D++ V G++L EI Sbjct: 476 TLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDGYYWITGRVD-DVLNVSGHRLGTAEI 532 Query: 415 EAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKD 236 E+ L+ H + E AV+G+P G+ I A + E+ S P L E + +W + Sbjct: 533 ESALVAHPKIAEAAVVGIPHAIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRK 585 Query: 235 KLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ P P LH DSLP+ GK+ Sbjct: 586 EIGPLATPDVLHWTDSLPKTRSGKI 610
>LGRB_BREPA (Q70LM6) Linear gramicidin synthetase subunit B [Includes:| ATP-dependent alanine adenylase (AlaA) (Alanine activase); ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine activase); Leucine racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-depende Length = 5162 Score = 73.6 bits (179), Expect = 6e-13 Identities = 51/163 (31%), Positives = 79/163 (48%), Gaps = 9/163 (5%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFI--------DGGFFKTGDTVTVDEDGYFIILGRTN 464 GEL + L + Y KRP++TAE F+ D + TGD V DG LGR + Sbjct: 3371 GELYLGGDGLARGYLKRPKMTAERFLPNPFHPDPDARMYSTGDLVRYLPDGQLEYLGRID 3430 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE-DARERAEQ 287 + K+ GY++ E+EAVL H + E V+ D+ + + A I K+ + +RA Sbjct: 3431 HQV-KIRGYRIELGELEAVLRSHPQIKEAVVVAKEDKLGEKRLVAYITTKDGECGDRA-- 3487 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 LTSW+K KL + +P+ D++P GK++ Sbjct: 3488 ---------VLTSWAKAKLPEFMVPSFFVWLDAMPLTPNGKID 3521 Score = 64.3 bits (155), Expect = 4e-10 Identities = 45/178 (25%), Positives = 76/178 (42%), Gaps = 7/178 (3%) Frame = -1 Query: 670 VEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDT 512 ++ I+ G GV GELCI SL + YW +T E F+ F ++TGD Sbjct: 780 IQTHIVNKHGQLQPVGVPGELCIAGASLARGYWNNEALTNEKFVPHPFAAGQRMYRTGDL 839 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 332 +DG LGR + + K+ GY++ EI A L++ ++ + V+ D +C Sbjct: 840 ARYRQDGNIEYLGRIDHQV-KIRGYRIELDEIRAQLIQEASIRDAVVIARTDHNGQAYLC 898 Query: 331 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 A + + T+ AL + L Y +P+ + P + GK++ Sbjct: 899 AYFIADKQ------------WTVNALREALRQTLPDYMVPSHFIQMEEFPLTSSGKID 944 Score = 63.2 bits (152), Expect = 8e-10 Identities = 47/163 (28%), Positives = 72/163 (44%), Gaps = 8/163 (4%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRT 467 VGEL I SL + Y RP++T SF+ F ++TGD V DG +GR Sbjct: 1855 VGELYIGGKSLARGYRNRPDLTEASFVPNPFSPIEGARMYRTGDLVRYAADGSIEFIGRA 1914 Query: 466 NADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQ 287 + D + + G+++ EIE+ L H V E V+ D G + ER Sbjct: 1915 D-DQVSIRGFRVELGEIESALYAHPAVAESVVIVREDVTPGVKRLVAYAVLHEGEERQTS 1973 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + +L K+ L Y +P+ + L ++LP GKV+ Sbjct: 1974 ELRQSL---------KEMLPDYMVPSAIVLMEALPLTPNGKVD 2007 Score = 61.6 bits (148), Expect = 2e-09 Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 8/162 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------FKTGDTVTVDEDGYFIILGRTN 464 GEL I L + Y RP++TAE F+ F ++TGD V DG +GR + Sbjct: 4431 GELYIGGDGLAEGYLNRPDLTAERFVPNPFATDQAARLYRTGDLVRYLPDGLIEFIGRLD 4490 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 + K+ G+++ E+EAVL +H + V+ +EA + + A V +DA + A Sbjct: 4491 NQV-KIRGFRIELSEVEAVLAKHPAITASVVIVHENEAGMKQLVAYAV--KDAEQELGTA 4547 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L K + Y +P + D+LP GKV+ Sbjct: 4548 E--------LRQHFKAHVPDYMVPAAFVMLDALPLTPNGKVD 4581
>4CL4_ARATH (Q9LU36) 4-coumarate--CoA ligase 4 (EC 6.2.1.12) (4CL 4) (At4CL4)| (4-coumaroyl-CoA synthase 4) (4-coumarate CoA ligase isoform 5) Length = 570 Score = 73.2 bits (178), Expect = 8e-13 Identities = 45/153 (29%), Positives = 78/153 (50%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+C++ L K Y PE TA + G+ TGD VD+D I+ R +++K G Sbjct: 414 GEICVRGHQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLK-ELIKFKG 472 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 Y+++ E+EA+L+ H ++ + AV+ + DE EV A + AR + Q LT + Sbjct: 473 YQVAPAELEALLISHPSIDDAAVVAMKDEVADEVPVAFV-----ARSQGSQ-----LTED 522 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + S+ ++ YK + + +P+ GK+ Sbjct: 523 DVKSYVNKQVVHYKRIKMVFFIEVIPKAVSGKI 555
>4CL3_ARATH (Q9S777) 4-coumarate--CoA ligase 3 (EC 6.2.1.12) (4CL 3) (At4CL3)| (4-coumaroyl-CoA synthase 3) Length = 561 Score = 73.2 bits (178), Expect = 8e-13 Identities = 43/153 (28%), Positives = 80/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + KEY PE T+ + + G+ TGD VDED I+ R +++K G Sbjct: 410 GEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLK-EVIKFKG 468 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 +++ E+E++L+ H ++ + AV+ DE GEV A +V +++ +T E Sbjct: 469 FQVPPAELESLLINHHSIADAAVVPQNDEVAGEVPVAFVV----------RSNGNDITEE 518 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + ++ YK ++ S+P++ GK+ Sbjct: 519 DVKEYVAKQVVFYKRLHKVFFVASIPKSPSGKI 551
>4CL1_SOYBN (P31686) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) (Clone 4CL14) (Fragment) Length = 293 Score = 72.8 bits (177), Expect = 1e-12 Identities = 43/153 (28%), Positives = 76/153 (49%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y E T + G+ TGD +D+D I+ R +++K G Sbjct: 136 GEICIRGDQIMKGYLNDGEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLK-ELIKYKG 194 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+LL H + + AV+ + DEA GEV A +V + E K ++ + Sbjct: 195 FQVAPAELEALLLTHPKISDAAVVPMKDEAAGEVPVAFVVISNGYTDTTEDEIKQFISKQ 254 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + YK R+ D++P++ GK+ Sbjct: 255 VVF---------YKRINRVFFIDAIPKSPSGKI 278
>LUCI_PHOPE (Q27757) Luciferin 4-monooxygenase (EC 1.13.12.7) (Luciferase)| Length = 545 Score = 72.4 bits (176), Expect = 1e-12 Identities = 36/100 (36%), Positives = 57/100 (57%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GEL K + K Y+ E T G+ ++GD D DG+F I+ R + ++K G Sbjct: 387 GELYFKGDMIMKSYYNNEEATKAIINKDGWLRSGDIAYYDNDGHFYIVDRLKS-LIKYKG 445 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 Y+++ EIE +LL+H +++ V G+PDEA GE+ A +V Sbjct: 446 YQVAPAEIEGILLQHPYIVDAGVTGIPDEAAGELPAAGVV 485
>4CL2_SOLTU (P31685) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) Length = 545 Score = 72.0 bits (175), Expect = 2e-12 Identities = 41/153 (26%), Positives = 80/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y PE TA + G+ TGD +D+D I+ R +++K G Sbjct: 389 GEICIRGDQIMKGYLNDPEATARTIEKEGWLHTGDIGFIDDDDELFIVDRLK-ELIKYKG 447 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+L+ H + + AV+ + DE GEV A +V +++ +T + Sbjct: 448 FQVAPAELEALLINHPDISDAAVVPMIDEQAGEVPVAFVV----------RSNGSTITED 497 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + ++ YK R+ +++P++ GK+ Sbjct: 498 EVKDFISKQVIFYKRIKRVFFVETVPKSPSGKI 530
>4CL1_SOLTU (P31684) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 545 Score = 72.0 bits (175), Expect = 2e-12 Identities = 41/153 (26%), Positives = 80/153 (52%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y PE TA + G+ TGD +D+D I+ R +++K G Sbjct: 389 GEICIRGDQIMKGYLNDPEATARTIEKEGWLHTGDIGFIDDDDELFIVDRLK-ELIKYKG 447 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 ++++ E+EA+L+ H + + AV+ + DE GEV A +V +++ +T + Sbjct: 448 FQVAPAELEALLINHPDISDAAVVPMIDEQAGEVPVAFVV----------RSNGSTITED 497 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + ++ YK R+ +++P++ GK+ Sbjct: 498 EVKDFISKQVIFYKRIKRVFFVETVPKSPSGKI 530
>ACSA_ECO57 (Q8X5T5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 72.0 bits (175), Expect = 2e-12 Identities = 49/145 (33%), Positives = 76/145 (52%) Frame = -1 Query: 595 SLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEI 416 +LF ++ +R E T S +F +GD DED Y+ I GR + D++ V G++L EI Sbjct: 476 TLFGDH-ERFEQTYFSTFKNMYF-SGDGARRDEDSYYWITGRVD-DVLNVSGHRLGTAEI 532 Query: 415 EAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKD 236 E+ L+ H + E AV+G+P G+ I A + E+ S P L E + +W + Sbjct: 533 ESALVAHPKIAEAAVVGIPHNIKGQAIYAYV-----TLNHGEEPS-PELYAE-VRNWVRK 585 Query: 235 KLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ P P LH DSLP+ GK+ Sbjct: 586 EIGPLATPDVLHWTDSLPKTRSGKI 610
>ACSA_DEIRA (Q9RRL7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 71.6 bits (174), Expect = 2e-12 Identities = 52/176 (29%), Positives = 87/176 (49%), Gaps = 6/176 (3%) Frame = -1 Query: 670 VEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF---IDGGFFKTGDTV 509 VE ++ DG E D G L + PS+ + + E +S+ I +F GD Sbjct: 450 VEPALMTRDGEEIGDDDGGLLVIKRPWPSMLRTVYGDDERYRKSYWGEIPHVYF-AGDGA 508 Query: 508 TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICA 329 D DGY+ I+GR + D++ V G++L +EIE+ L+ H V E AV+G PD GE + A Sbjct: 509 RRDHDGYYTIVGRVD-DVLNVSGHRLGTMEIESALVAHPDVSEAAVVGRPDPVKGESVVA 567 Query: 328 IIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ ++ + PA AL + ++ P +++ D+LP+ GK+ Sbjct: 568 YVLLQDG------HTADPA----ALRAHVSSEIGALARPDAIYIADALPKTRSGKI 613
>ACS2L_HUMAN (Q9NUB1) Acetyl-coenzyme A synthetase 2-like, mitochondrial| precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (Acyl-CoA synthetase short-chain family member 1) Length = 689 Score = 71.6 bits (174), Expect = 2e-12 Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 7/173 (4%) Frame = -1 Query: 658 IIMDDGTETKDGV---GELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVD 500 ++MD+ +G G LCI P + + + + +++ G++ TGD Sbjct: 479 VLMDEKGSVVEGSNVSGALCISQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRT 538 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E GY+ I GR + D++ + G++L EIE + +H V E AV+G P + GE A IV Sbjct: 539 EGGYYQITGRMD-DVINISGHRLGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIV 597 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K+ A + + ++ L S K+A Y +P + + LP+ GKV Sbjct: 598 VKDSAGD-------SDVVVQELKSMVATKIAKYAVPDEILVVKRLPKTRSGKV 643
>ACSA_STRAW (Q82EL5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 71.6 bits (174), Expect = 2e-12 Identities = 49/178 (27%), Positives = 84/178 (47%), Gaps = 6/178 (3%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGVGELCIKS---PSLFKEYWKRPEVTAESF---IDGGFFKTGD 515 P + A ++ D+ E +G G + + PS+ + W + +++ +G +F GD Sbjct: 443 PGISATVVDDEAREVPNGGGGYLVLTEPWPSMLRTIWGDDQRFLDTYWSRFEGKYF-AGD 501 Query: 514 TVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI 335 DEDG +LGR + D+M V G+ +S E+E+ L+ H +V E AV+G DE G+ I Sbjct: 502 GAKKDEDGDIWLLGRVD-DVMLVSGHNISTTEVESALVSHPSVAEAAVVGAADETTGQAI 560 Query: 334 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A ++ + A + + L + L P P R+ LP+ GK+ Sbjct: 561 VAFVILRGTANAEDDN------LVADLRNHVGTTLGPIAKPKRILPVAELPKTRSGKI 612
>ACSA_VIBCH (Q9KV59) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 649 Score = 71.2 bits (173), Expect = 3e-12 Identities = 39/125 (31%), Positives = 64/125 (51%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD DEDGY+ I GR + D++ V G+++ EIE+ L+ + + E AV+G+P Sbjct: 494 GMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESALVAFNKIAEAAVVGVPH 552 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ I A I + AE + + W + ++ P LH D+LP+ Sbjct: 553 DIKGQAIYAYITLNDGVYPSAELHKE-------VKDWVRKEIGAIATPDVLHWTDALPKT 605 Query: 175 AMGKV 161 GK+ Sbjct: 606 RSGKI 610
>ACSA_RHOCA (O68040) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 656 Score = 70.9 bits (172), Expect = 4e-12 Identities = 49/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%) Frame = -1 Query: 658 IIMDDGTETKDGV----GELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTV 503 +++D T + G G LCI P + W + E++ G++ TGD Sbjct: 452 VVLDPQTAVRIGEVECEGVLCISDSWPGQMRTVWGDHDRFQETYFGQYRGYYFTGDGCRR 511 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 D+DGY+ I GR + D++ V G+++ E+E+ L+ H V E AV+G P + G+ I A + Sbjct: 512 DKDGYYWITGRVD-DVINVSGHRMGTAEVESALVAHPQVAEAAVVGYPHDIKGQGIYAYV 570 Query: 322 V------PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 P ED R + L W + ++ P P + LP+ GK+ Sbjct: 571 TLMNGIEPSEDLR-------------KDLVKWVRTEIGPIASPDLIQWAPGLPKTRSGKI 617
>4CL2_ARATH (Q9S725) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (At4Cl2)| (4-coumaroyl-CoA synthase 2) Length = 556 Score = 70.1 bits (170), Expect = 7e-12 Identities = 43/171 (25%), Positives = 87/171 (50%), Gaps = 2/171 (1%) Frame = -1 Query: 667 EAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDED 494 E KI+ D ++ ++ GE+CI+ + K Y P TA + G+ TGD +D+D Sbjct: 382 EMKILDPDTGDSLPRNKPGEICIRGNQIMKGYLNDPLATASTIDKDGWLHTGDVGFIDDD 441 Query: 493 GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPK 314 I+ R +++K G++++ E+E++L+ H + + AV+ + +E GEV A +V Sbjct: 442 DELFIVDRLK-ELIKYKGFQVAPAELESLLIGHPEINDVAVVAMKEEDAGEVPVAFVVRS 500 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 +D+ ++ + + + ++ YK ++ DS+P+ GK+ Sbjct: 501 KDSN----------ISEDEIKQFVSKQVVFYKRINKVFFTDSIPKAPSGKI 541
>ACSA2_PSEAE (Q9HV66) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 645 Score = 70.1 bits (170), Expect = 7e-12 Identities = 50/172 (29%), Positives = 84/172 (48%), Gaps = 6/172 (3%) Frame = -1 Query: 658 IIMDDGTETKDGVGE--LCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDE 497 +++D+ + DG G L IK+ PS + + + +++ G++ +GD DE Sbjct: 444 VLLDEKGKEIDGAGSGVLAIKASWPSQIRSVYGDHQRMIDTYFKPYPGYYFSGDGARRDE 503 Query: 496 DGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 DGY+ I GR + D++ V G+++ E+E+ L+ HD V E AV+G P + G+ I A + Sbjct: 504 DGYYWITGRVD-DVINVSGHRIGTAEVESALVLHDAVAEAAVVGCPHDVKGQAIYAFVT- 561 Query: 316 KEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A AL E L K+ + + P L SLP+ GK+ Sbjct: 562 -----LMAGSQPSEALQQELLALVGKE-IGSFAKPDHLQWAPSLPKTRSGKI 607
>ACSA_PHYBL (Q01576) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 672 Score = 70.1 bits (170), Expect = 7e-12 Identities = 46/157 (29%), Positives = 79/157 (50%), Gaps = 4/157 (2%) Frame = -1 Query: 619 GELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIM 452 G L I+ P S+ + + E+++ G++ TGD D+DGY I GR + D++ Sbjct: 478 GVLAIRKPRPSMARSVYNNHSRFVETYLKPYPGYYFTGDGALRDDDGYIWIRGRVD-DVI 536 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 V G++LS EIE+ L+ H+ V E AV+G D+ G+ I A + K + + Sbjct: 537 NVSGHRLSTSEIESALVNHEAVAESAVVGAHDDLTGQCIHAFVSLKPHI--QIADGLEKV 594 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 LTL+ + + P+ P R+++ P+ GK+ Sbjct: 595 LTLQV-----RKTIGPFAAPRRIYIVSDHPKTRSGKI 626
>MENE_STAES (Q8CS21) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 70.1 bits (170), Expect = 7e-12 Identities = 43/155 (27%), Positives = 77/155 (49%) Frame = -1 Query: 625 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKV 446 G GEL IK ++ Y P+ ++F + G+F+TGD +D++GY II R D++ Sbjct: 316 GHGELLIKGENVMNGYLY-PKYLKDTFDNDGYFQTGDIAEIDDEGYVIIYDR-RKDLIIS 373 Query: 445 GGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALT 266 GG + +IE + + + + + +G+ D+ +G+V V +D + Sbjct: 374 GGENIYPYQIETIAKDFEGIEDAVCVGISDDTWGQVPILYYVTNQDINQ----------- 422 Query: 265 LEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L ++ LA YKIP + + +SLP + GK+ Sbjct: 423 -NELIEHFENHLARYKIPKKYYQVESLPYTSTGKL 456
>ACSA_BRAJA (Q89WV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 648 Score = 69.7 bits (169), Expect = 9e-12 Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 12/182 (6%) Frame = -1 Query: 670 VEAKIIMDDGTETK-DGVGELCIKS--PSLFKEYW---KRPEVTAESFIDGGFFKTGDTV 509 V +I+ DG + + G LC+ P + + + R E T S G +F TGD Sbjct: 441 VVPEIVDADGKVLEGETTGNLCLTRAWPGMMRTVYGDHARFEQTYFSTYKGKYF-TGDGC 499 Query: 508 TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICA 329 D DGY+ I GR + D++ V G+++ E+E+ L+ H+ V E AV+G P + G+ I A Sbjct: 500 RRDADGYYWITGRVD-DVINVSGHRMGTAEVESALVAHEKVSEAAVVGFPHDIKGQGIYA 558 Query: 328 IIV------PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMG 167 + P ED R+ L +W + ++ P P ++ LP+ G Sbjct: 559 YVTLMAGVQPTEDLRKE-------------LVTWVRKEIGPIASPDQIQFAPGLPKTRSG 605 Query: 166 KV 161 K+ Sbjct: 606 KI 607
>MENE_ENTFA (Q838K1) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 485 Score = 69.7 bits (169), Expect = 9e-12 Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 1/171 (0%) Frame = -1 Query: 670 VEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDED 494 ++ KI+ + G E + VGE+ +K P++ Y + + E + G+FKTGD +D Sbjct: 314 MQIKIVDELGQEQPEKQVGEILLKGPNVVSGYLNQRQ--PEKWTADGWFKTGDMGYLDAQ 371 Query: 493 GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPK 314 Y ++ R + I+ GG + E+E VL + AV+G PD +G V A ++ Sbjct: 372 SYLYLVSRLSELIIS-GGENIYPTEVEQVLQAITGIKAAAVVGEPDAQWGAVPVAYVISD 430 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ +TL + KLA YK P R++ S P+ A GK+ Sbjct: 431 QE------------ITLAQIQDQCSRKLAKYKRPKRIYFCHSFPQTASGKI 469
>ACSA_CAUCR (Q9A2I0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 69.7 bits (169), Expect = 9e-12 Identities = 42/125 (33%), Positives = 65/125 (52%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD D DGY+ I GR + D++ V G++L EIE+ L+ H+TV E AV+G P Sbjct: 493 GKYFTGDGCRRDADGYYWITGRVD-DVINVSGHRLGTAEIESALVAHETVAEAAVVGYPH 551 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ + A + K A A A + L L W + ++ P+ P + LP+ Sbjct: 552 DIKGQGVYAYVTLK--AGIEATDALRKDLVL-----WVRHEIGPFAAPDVIQWAPGLPKT 604 Query: 175 AMGKV 161 GK+ Sbjct: 605 RSGKI 609
>BAIB_EUBSP (P19409) Bile acid-coenzyme A ligase (EC 6.-.-.-)| Length = 520 Score = 68.6 bits (166), Expect = 2e-11 Identities = 51/159 (32%), Positives = 77/159 (48%), Gaps = 4/159 (2%) Frame = -1 Query: 622 VGELCIKSPS--LFKEY--WKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADI 455 +GE+ + +P+ L EY W+ EV +GGF GD VDE GY R +D+ Sbjct: 367 IGEIYMTAPASYLVTEYINWEPLEVK-----EGGFRSVGDIGYVDEQGYLYFSDR-RSDM 420 Query: 454 MKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKP 275 + GG + A E+E LL + +L+ V+G+PDE G + A+I E +E Sbjct: 421 LVSGGENVFATEVETALLRYKDILDAVVVGIPDEDLGRRLHAVI---ETGKE-------- 469 Query: 274 ALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + E L ++ + L PYKIP S+ R GK + Sbjct: 470 -IPAEELKTFLRKYLTPYKIPKTFEFVRSIRRGDNGKAD 507
>ACSA_HUMAN (Q9NR19) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 68.6 bits (166), Expect = 2e-11 Identities = 41/125 (32%), Positives = 63/125 (50%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G++ TGD D+DGY+ I GR + D++ V G+ LS E+E+ L+EH+ V E AV+G P Sbjct: 546 GYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPH 604 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 GE + + + P LT E L ++K+ P P + LP+ Sbjct: 605 PVKGECLYCFVTLCDG------HTFSPKLT-EELKKQIREKIGPIATPDYIQNAPGLPKT 657 Query: 175 AMGKV 161 GK+ Sbjct: 658 RSGKI 662
>ACSA_CHLTE (Q8KBY0) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 659 Score = 68.6 bits (166), Expect = 2e-11 Identities = 54/183 (29%), Positives = 85/183 (46%), Gaps = 11/183 (6%) Frame = -1 Query: 676 PRVEAKIIMDDGT--ETKDGVGELCIKSP--SLFKEYW---KRPEVTAESFIDGGFFKTG 518 P + ++ DGT +G G L +K P S+ + + +R E T S G +F TG Sbjct: 454 PGIMVDVVRKDGTPCNANEG-GYLVVKRPWPSMLRTIYGDNERYEKTYWSEFPGMYF-TG 511 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D D+DGY I+GR + D++ V G++L E+E+ L+ H+ V E AV+ PDE G Sbjct: 512 DGARKDDDGYIWIMGRVD-DVVNVSGHRLGTSEVESALVSHEAVAEAAVVSRPDEIKGNA 570 Query: 337 ICAIIVPKE----DARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAM 170 + A + K+ DA+ R A + A+ P + LP+ Sbjct: 571 LVAFVTLKDGYEGDAKLRDSLGKHVAKEIGAIAK-----------PDEIRWAKGLPKTRS 619 Query: 169 GKV 161 GK+ Sbjct: 620 GKI 622
>MENE_STAEQ (Q5HNB2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 474 Score = 68.6 bits (166), Expect = 2e-11 Identities = 43/155 (27%), Positives = 76/155 (49%) Frame = -1 Query: 625 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKV 446 G GEL IK ++ Y P+ ++F + G+F+TGD +D++GY II R D++ Sbjct: 316 GHGELLIKGENVMNGYLY-PKYLKDTFDNDGYFQTGDIAEIDDEGYVIIYDR-RKDLIIS 373 Query: 445 GGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALT 266 GG + +IE + + + + + +G+ D+ +G+V V +D + Sbjct: 374 GGENIYPYQIETIAKDFEGIEDAVCVGISDDTWGQVPILYYVTNQDINQ----------- 422 Query: 265 LEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L ++ LA YKIP + + SLP + GK+ Sbjct: 423 -TELIEHFENHLARYKIPKKYYQVKSLPYTSTGKL 456
>ACSA1_PSEPK (Q88EH6) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 653 Score = 68.2 bits (165), Expect = 3e-11 Identities = 42/125 (33%), Positives = 66/125 (52%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD DEDGY+ I GR + D++ V G+++ EIE+ ++ H V E AV+G+P Sbjct: 494 GMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESAMVAHSKVAEAAVVGVPH 552 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ I + V E +EQ L LE L +W + ++ P P + LP+ Sbjct: 553 DIKGQGI-YVYVTLNAGIEASEQ-----LRLE-LKNWVRKEIGPIASPDVIQWAPGLPKT 605 Query: 175 AMGKV 161 GK+ Sbjct: 606 RSGKI 610
>ACSA_DROME (Q9VP61) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) Length = 670 Score = 68.2 bits (165), Expect = 3e-11 Identities = 49/175 (28%), Positives = 83/175 (47%), Gaps = 5/175 (2%) Frame = -1 Query: 670 VEAKIIMDDGTETK-DGVGELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVT 506 V+ ++ + G E K +G G L P + + + E +++ G++ TGD Sbjct: 465 VKPTLLDECGIEIKGEGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGAR 524 Query: 505 VDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI 326 D DGY I GR + D++ V G+ +S E+E+VL EH V E AV+ P GE + Sbjct: 525 RDADGYLWITGRVD-DMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCF 583 Query: 325 IVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 I P E+ E +Q + L ++++ P+ +P + LP+ GK+ Sbjct: 584 ITPNEN--EVFDQK-----LISDLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKI 631
>MENE_STAAW (Q8NVZ4) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 68.2 bits (165), Expect = 3e-11 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 K+G GEL IK ++ Y ++T + G+F TGD +D +GY +I R D++ Sbjct: 343 KEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR-RKDLI 399 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 GG + +IE V + + + +G PD+ +G+V V + D Sbjct: 400 ISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESD------------ 447 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L ++ LA YK+P D+LP + GK+ Sbjct: 448 ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAU (Q53634) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 68.2 bits (165), Expect = 3e-11 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 K+G GEL IK ++ Y ++T + G+F TGD +D +GY +I R D++ Sbjct: 343 KEGHGELMIKGANVMNVYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR-RKDLI 399 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 GG + +IE V + + + +G PD+ +G+V V + D Sbjct: 400 ISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESD------------ 447 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L ++ LA YK+P D+LP + GK+ Sbjct: 448 ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAS (Q6G8D6) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 68.2 bits (165), Expect = 3e-11 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 K+G GEL IK ++ Y ++T + G+F TGD +D +GY +I R D++ Sbjct: 343 KEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR-RKDLI 399 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 GG + +IE V + + + +G PD+ +G+V V + D Sbjct: 400 ISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESD------------ 447 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L ++ LA YK+P D+LP + GK+ Sbjct: 448 ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAC (Q5HEY2) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 68.2 bits (165), Expect = 3e-11 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 K+G GEL IK ++ Y ++T + G+F TGD +D +GY +I R D++ Sbjct: 343 KEGHGELMIKGANVMNVYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR-RKDLI 399 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 GG + +IE V + + + +G PD+ +G+V V + D Sbjct: 400 ISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESD------------ 447 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L ++ LA YK+P D+LP + GK+ Sbjct: 448 ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>ACS2L_MOUSE (Q99NB1) Acetyl-coenzyme A synthetase 2-like, mitochondrial| precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) Length = 682 Score = 68.2 bits (165), Expect = 3e-11 Identities = 47/173 (27%), Positives = 84/173 (48%), Gaps = 7/173 (4%) Frame = -1 Query: 658 IIMDDGTETKDG---VGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVD 500 ++MD+ +G G LCI P + + + + +++ G++ TGD Sbjct: 472 VLMDEKGNVLEGGDVSGALCISQAWPGMARTIYGDHQRFVDAYFRAYPGYYFTGDGAHRT 531 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 E GY+ I GR + D++ + G++L EIE + +H V E AV+G P + GE A IV Sbjct: 532 EGGYYQITGRMD-DVINISGHRLGTAEIEDAMADHPAVPETAVIGYPHDIKGEAAFAFIV 590 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 K++ + ++ L++ K+A Y +P ++ + LP+ GKV Sbjct: 591 LKDNISDENMVVNELKLSVAT-------KIAKYAVPDQILVVKRLPKTRSGKV 636
>ACSA_SHEON (Q8EDK3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 650 Score = 68.2 bits (165), Expect = 3e-11 Identities = 38/125 (30%), Positives = 60/125 (48%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD DEDGY+ I GR + D++ V G++L E+E+ L+ H+ V E AV+G P Sbjct: 494 GMYFTGDGARRDEDGYYWITGRVD-DVINVSGHRLGTAEVESALVSHELVAEAAVVGYPH 552 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ I A + E E + L W + ++ P + LP+ Sbjct: 553 DIKGQGIYAYVTLTRGTEESEE-------LRQELRQWVRKEIGALATPDLIQWATGLPKT 605 Query: 175 AMGKV 161 GK+ Sbjct: 606 RSGKI 610
>ACSA_BRUSU (Q8FYQ3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 67.8 bits (164), Expect = 3e-11 Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 6/172 (3%) Frame = -1 Query: 658 IIMDDGTETKDGV--GELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDE 497 +++D+ ++GV G LCI P + + + E++ G + +GD DE Sbjct: 447 VLVDNEGNVQEGVADGNLCISDSWPGQMRTVYGDHKRFIETYFSTYKGMYFSGDGCRRDE 506 Query: 496 DGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 DGY+ I GR + D++ + G++L EIE+ L+ H +V E AV+G P G+ I + Sbjct: 507 DGYYWITGRVD-DVLNISGHRLGTAEIESALVSHHSVSEAAVVGYPHPIKGQGIYCYVTL 565 Query: 316 KEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A A P + L + ++ P P ++ LP+ GK+ Sbjct: 566 MTGA-----DAQDPDELRKELVQHVRKEIGPIATPDKIQFAPGLPKTRSGKI 612
>ACSA_BRUME (Q8YJ48) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 67.8 bits (164), Expect = 3e-11 Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 6/172 (3%) Frame = -1 Query: 658 IIMDDGTETKDGV--GELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDE 497 +++D+ ++GV G LCI P + + + E++ G + +GD DE Sbjct: 447 VLVDNEGNVQEGVADGNLCISDSWPGQMRTVYGDHKRFIETYFSTYKGMYFSGDGCRRDE 506 Query: 496 DGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 DGY+ I GR + D++ + G++L EIE+ L+ H +V E AV+G P G+ I + Sbjct: 507 DGYYWITGRVD-DVLNISGHRLGTAEIESALVSHHSVSEAAVVGYPHPIKGQGIYCYVTL 565 Query: 316 KEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A A P + L + ++ P P ++ LP+ GK+ Sbjct: 566 MTGA-----DAQDPDELRKELVQHVRKEIGPIATPDKIQFAPGLPKTRSGKI 612
>MENE_STAAN (P63526) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 K+G GEL IK ++ Y ++T + G+F TGD +D +GY +I R D++ Sbjct: 343 KEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR-RKDLI 399 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 GG + +IE V + + + +G PD+ +G+V V + D Sbjct: 400 ISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESD------------ 447 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L ++ LA YK+P D+LP + GK+ Sbjct: 448 ISKAQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKL 484
>MENE_STAAM (P63525) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 67.8 bits (164), Expect = 3e-11 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 K+G GEL IK ++ Y ++T + G+F TGD +D +GY +I R D++ Sbjct: 343 KEGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR-RKDLI 399 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 GG + +IE V + + + +G PD+ +G+V V + D Sbjct: 400 ISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESD------------ 447 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L ++ LA YK+P D+LP + GK+ Sbjct: 448 ISKAQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKL 484
>ACSA_XANAC (Q8PF09) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/131 (30%), Positives = 61/131 (46%), Gaps = 6/131 (4%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD D DGY+ I GR + D++ V G+++ E+E+ L+ H V E AV+G P Sbjct: 493 GSYFTGDGCRRDADGYYWITGRVD-DVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPH 551 Query: 355 EAYGEVICAII------VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLW 194 + G+ I A + P ED + L SW + ++ P P L Sbjct: 552 DVKGQGIYAYVTLIAGQTPSEDLHKE-------------LVSWVRKEIGPIASPDHLQWA 598 Query: 193 DSLPRNAMGKV 161 LP+ GK+ Sbjct: 599 PGLPKTRSGKI 609
>ACSA_CAMJE (Q9PMD2) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 657 Score = 67.0 bits (162), Expect = 6e-11 Identities = 51/181 (28%), Positives = 89/181 (49%), Gaps = 9/181 (4%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSP--SLFKEYWKRPEVTAESFI-----DG-GFFK 524 P + A++I ++G + +G G LCI P S+ + W E ES+ DG + Sbjct: 442 PGIFAEVIDEEGNKKDEGEDGLLCITKPWPSMIRGIWGNDERYIESYFSQAKKDGKAVYF 501 Query: 523 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 344 +GD D++GY I GRT+ D++ V G+++ EIE+ + +H +V E AV+ + D G Sbjct: 502 SGDGAFYDKNGYITITGRTD-DVVNVAGHRIGTAEIESAIAKHPSVAESAVVSILDTIKG 560 Query: 343 EVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGK 164 E + A +V + A + TL+ L + ++ P ++ LP+ GK Sbjct: 561 ESLFAFVVLSPASSCDLGGAIE---TLKELNDILRVEIGPIAKIEKILYTPGLPKTRSGK 617 Query: 163 V 161 + Sbjct: 618 I 618
>MENE_STAAR (Q6GFR0) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 492 Score = 67.0 bits (162), Expect = 6e-11 Identities = 43/157 (27%), Positives = 73/157 (46%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 K G GEL IK ++ Y ++T + G+F TGD +D +GY +I R D++ Sbjct: 343 KKGHGELMIKGANVMNGYLYPTDLTGT--FENGYFNTGDIAEIDHEGYVMIYDR-RKDLI 399 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPA 272 GG + +IE V + +++ +G PD+ +G+V V S+ Sbjct: 400 ISGGENIYPYQIETVAKQFPGIIDAVCVGHPDDTWGQVPKLYFV------------SESN 447 Query: 271 LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L ++ LA YK+P D+LP + GK+ Sbjct: 448 ISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKL 484
>SRFAA_BACSU (P27206) Surfactin synthetase subunit 1| Length = 3588 Score = 67.0 bits (162), Expect = 6e-11 Identities = 50/162 (30%), Positives = 72/162 (44%), Gaps = 8/162 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELC+ L K Y+ RPE+T E F+ F +KTGD +G +GR + Sbjct: 1843 GELCVTGEGLVKGYYNRPELTEEKFVPHPFTSGERMYKTGDLARWLPNGTIEFIGRIDHQ 1902 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED--ARERAEQA 284 + K+ G + EIE L HD V E VL + A +++CA V + D ++E E A Sbjct: 1903 V-KIRGQAIELGEIEHQLQTHDRVQESVVLAVDQGAGDKLLCAYYVGEGDISSQEMREHA 1961 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +K L Y +P D LP GK++ Sbjct: 1962 AK--------------DLPAYMVPAVFIQMDELPLTGNGKID 1989 Score = 62.4 bits (150), Expect = 1e-09 Identities = 54/174 (31%), Positives = 77/174 (44%), Gaps = 7/174 (4%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 500 I+ G +GV GEL I + + Y PE+T E F+ F ++TGD V Sbjct: 790 ILDQKGRLQPEGVAGELYIAGDGVGRGYLHLPELTEEKFLQDPFVPGDRMYRTGDVVRWL 849 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 DG LGR + D +KV GY++ EIEAV+ + V + VL PDE +CA +V Sbjct: 850 PDGTIEYLGRED-DQVKVRGYRIELGEIEAVIQQAPDVAKAVVLARPDEQGNLEVCAYVV 908 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 K + PA L + +L Y +P +P GKV+ Sbjct: 909 QKPGSE------FAPA----GLREHAARQLPDYMVPAYFTEVTEIPLTPSGKVD 952 Score = 61.2 bits (147), Expect = 3e-09 Identities = 53/174 (30%), Positives = 80/174 (45%), Gaps = 8/174 (4%) Frame = -1 Query: 655 IMDDGTETK-DGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 500 I+ +G + + +GV GELC+ L + Y R + TA+ F+ F ++TGD V Sbjct: 2863 ILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVKWT 2922 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 G I GR + + KV GY++ EIE L + V + AV + D+ I A + Sbjct: 2923 GGGIEYI-GRIDQQV-KVRGYRIELSEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYVT 2980 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 P+ + +EAL S K+ L Y IP + LP A GKV+ Sbjct: 2981 PE-------------SADIEALKSALKETLPDYMIPAFWVTLNELPVTANGKVD 3021
>ACSA_PSESM (Q885K7) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 66.6 bits (161), Expect = 7e-11 Identities = 39/125 (31%), Positives = 63/125 (50%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD DEDGY+ I GR + D++ V G+++ EIE+ ++ H V E AV+G+P Sbjct: 494 GMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEIESAMVAHPKVAEAAVVGVPH 552 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 + G+ I + A + AL E L +W + ++ P P + LP+ Sbjct: 553 DLKGQGIYVYVT------LNAGEEPSDALRTE-LRNWVRKEIGPIASPDFIQWAPGLPKT 605 Query: 175 AMGKV 161 GK+ Sbjct: 606 RSGKI 610
>4CL1_ORYSA (P17814) 4-coumarate--CoA ligase 1 (EC 6.2.1.12) (4CL 1)| (4-coumaroyl-CoA synthase 1) Length = 564 Score = 66.2 bits (160), Expect = 1e-10 Identities = 48/171 (28%), Positives = 80/171 (46%), Gaps = 2/171 (1%) Frame = -1 Query: 667 EAKIIMDDGTET--KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDED 494 E KII D ++ ++ GE+CI+ + K Y PE T + G+ TGD VD+D Sbjct: 388 ELKIIDPDTGKSLGRNLPGEICIRGQQIMKGYLNNPEATKNTIDAEGWLHTGDIGYVDDD 447 Query: 493 GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPK 314 I+ R +I+K G++++ E+EA+L+ H ++ + AV+G E I V K Sbjct: 448 DEIFIVDRLK-EIIKYRGFQVAPAELEALLITHPSIADAAVVGKQIEPEIGEIPVAFVAK 506 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + E +E K + E + YK + D +P+ GK+ Sbjct: 507 TEGSELSEDDVKQFVAKEVIY---------YKKIREVFFVDKIPKAPSGKI 548
>DHBF_BACSU (P45745) Dimodular nonribosomal peptide synthetase| Length = 2378 Score = 65.9 bits (159), Expect = 1e-10 Identities = 43/161 (26%), Positives = 76/161 (47%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGDTVTVDEDGYFIILGRTNA 461 GEL + L + Y RP +T+E FI F ++TGD + DG +GR + Sbjct: 1871 GELYVSGAGLARGYLGRPGLTSERFIADPFGPPGTRMYRTGDVARLRADGSLDYVGRADH 1930 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 + K+ G+++ EIEA L++H + + AV+ D+ + + A ++P E+ + AE Sbjct: 1931 QV-KIRGFRIELGEIEAALVQHPQLEDAAVIVREDQPGDKRLAAYVIPSEETFDTAE--- 1986 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L ++ ++L Y +P LP GK++ Sbjct: 1987 --------LRRYAAERLPDYMVPAAFVTMKELPLTPNGKLD 2019 Score = 58.9 bits (141), Expect = 2e-08 Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 7/162 (4%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF-------FKTGDTVTVDEDGYFIILGRTN 464 VGEL I L + Y+ RP++TAE F+ + ++TGD DG +GR + Sbjct: 796 VGELYIAGTGLARGYFHRPDLTAERFVADPYGPPGTRMYRTGDQARWRADGSLDYIGRAD 855 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 I K+ G+++ EI+AVL H + + AV+ D+ + + A +V Sbjct: 856 HQI-KIRGFRIELGEIDAVLANHPHIEQAAVVVREDQPGDKRLAAYVV------------ 902 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + A+ L + L Y +P+ D LP GK++ Sbjct: 903 ADAAIDTAELRRYMGASLPDYMVPSAFVEMDELPLTPNGKLD 944
>4CL2_SOYBN (P31687) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2)| (4-coumaroyl-CoA synthase 2) (Clone 4CL16) Length = 562 Score = 65.9 bits (159), Expect = 1e-10 Identities = 41/153 (26%), Positives = 77/153 (50%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CI+ + K Y TA + G+ TGD VD+D I+ R +++K G Sbjct: 404 GEICIRGQQIMKGYLNDEAATASTIDSEGWLHTGDVGYVDDDDEIFIVDRVK-ELIKYKG 462 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLE 260 +++ E+E +L+ H ++ + AV+ D A GEV A +V +++ LT E Sbjct: 463 FQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVV----------RSNGFDLTEE 512 Query: 259 ALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A+ + ++ YK +++ ++P++ GK+ Sbjct: 513 AVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKI 545
>ACSA_XANCP (Q8P3L1) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 65.9 bits (159), Expect = 1e-10 Identities = 39/127 (30%), Positives = 61/127 (48%), Gaps = 2/127 (1%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD D DGY+ I GR + D++ V G+++ E+E+ L+ H V E AV+G P Sbjct: 493 GSYFTGDGCRRDADGYYWITGRVD-DVINVSGHRIGTAEVESALVSHPKVAEAAVVGFPH 551 Query: 355 EAYGEVICAII--VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 182 + G+ I A + + E E + L SW + ++ P P L LP Sbjct: 552 DVKGQGIYAYVTLIAGETPSEELH---------KELVSWVRKEIGPIASPDHLQWAPGLP 602 Query: 181 RNAMGKV 161 + GK+ Sbjct: 603 KTRSGKI 609
>ACSA2_RHIME (Q92KX2) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 649 Score = 65.5 bits (158), Expect = 2e-10 Identities = 48/177 (27%), Positives = 84/177 (47%), Gaps = 7/177 (3%) Frame = -1 Query: 670 VEAKIIMDDGTETKDGV--GELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTV 509 V+ +I+ DG + DG G LCI P + + E +++ G + TGD Sbjct: 444 VQPQIVDSDG-KVVDGAADGNLCITDSWPGQMRTVYGDHERFIQTYFSTYKGKYFTGDGC 502 Query: 508 TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE-VIC 332 DEDGY+ I GR + D++ V G++L E+E+ L+ H+ V E AV+G P G+ + C Sbjct: 503 RRDEDGYYWITGRVD-DVLNVSGHRLGTAEVESALVSHNLVSEAAVVGYPHPIKGQGIYC 561 Query: 331 AIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + + + + +AL + ++ P P ++ LP+ GK+ Sbjct: 562 YVSLMAGEVGDDELR--------QALVKHVRSEIGPIATPDKIQFAPGLPKTRSGKI 610
>ACSA_AGRT5 (Q8UBV5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 65.1 bits (157), Expect = 2e-10 Identities = 49/160 (30%), Positives = 80/160 (50%), Gaps = 7/160 (4%) Frame = -1 Query: 619 GELCI------KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNAD 458 G LCI +S S++ ++ + + T S G +F TGD DEDGY+ I GR + D Sbjct: 462 GNLCIIDSWPGQSRSVYGDHQRFVD-TYFSTYKGKYF-TGDGCRRDEDGYYWITGRVD-D 518 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE-VICAIIVPKEDARERAEQAS 281 ++ V G++L E+E+ L+ H V E AV+G P G+ + C + + A Q+ Sbjct: 519 VLNVSGHRLGTAEVESALVSHHQVSEAAVVGYPHPIKGQGIYCYVTL-------MAGQSG 571 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 AL E L ++++ P P ++ LP+ GK+ Sbjct: 572 DYALR-EELVKHVRNEIGPVATPDKIQFAPGLPKTRSGKI 610
>PRPE_ECOLI (P77495) Propionate--CoA ligase (EC 6.2.1.17) (Propionyl-CoA| synthetase) Length = 628 Score = 64.3 bits (155), Expect = 4e-10 Identities = 45/143 (31%), Positives = 66/143 (46%), Gaps = 1/143 (0%) Frame = -1 Query: 586 KEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAV 407 K YW S + T D D DGY ILGRT+ D++ V G++L EIE Sbjct: 463 KTYW--------SLFSRPVYATFDWGIRDADGYHFILGRTD-DVINVAGHRLGTREIEES 513 Query: 406 LLEHDTVLECAVLGLPDEAYGEVICAIIVPKE-DARERAEQASKPALTLEALTSWSKDKL 230 + H V E AV+G+ D G+V A ++PKE D+ E + A + AL ++ Sbjct: 514 ISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALVD---SQI 570 Query: 229 APYKIPTRLHLWDSLPRNAMGKV 161 + P + LP+ GK+ Sbjct: 571 GNFGRPAHVWFVSQLPKTRSGKM 593
>SRFAB_BACSU (Q04747) Surfactin synthetase subunit 2| Length = 3587 Score = 64.3 bits (155), Expect = 4e-10 Identities = 49/160 (30%), Positives = 77/160 (48%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 G+L I L + Y RP++TAE F++ + +KTGD V DG +GR + D Sbjct: 1846 GQLYITGQGLARGYLNRPQLTAERFVENPYSPGSLMYKTGDVVRRLSDGTLAFIGRAD-D 1904 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 +K+ GY++ EIE V+L + E VL + + E +CA +D E+AE + Sbjct: 1905 QVKIRGYRIELGEIETVMLSLSGIQEAVVLAVSEGGLQE-LCAYYTSDQDI-EKAELRYQ 1962 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +LTL + + IP D++P A GK + Sbjct: 1963 LSLTLPS-----------HMIPAFFVQVDAIPLTANGKTD 1991 Score = 58.9 bits (141), Expect = 2e-08 Identities = 53/174 (30%), Positives = 79/174 (45%), Gaps = 8/174 (4%) Frame = -1 Query: 655 IMDDGTETK-DGV-GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVD 500 I+ +G + + +GV GELC+ L + Y R + TA+ F+ F ++TGD V Sbjct: 2862 ILGEGNQVQPEGVAGELCVAGRGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVKWV 2921 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV 320 G I GR + + KV GY++ EIE L + V + AV + D+ I A + Sbjct: 2922 NGGIEYI-GRIDQQV-KVRGYRIELSEIEVQLAQLSEVEDRAVTRVKDKGGNTAIAAYVT 2979 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 P+ +EAL S K+ L Y IP + LP A GKV+ Sbjct: 2980 PE-------------TADIEALKSTLKETLPDYMIPAFWVTLNELPVTANGKVD 3020 Score = 58.2 bits (139), Expect = 3e-08 Identities = 45/160 (28%), Positives = 68/160 (42%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELC+ + + Y PE+T + F++ F ++TGD DG LGR + Sbjct: 801 GELCVGGIGVARGYVNLPELTEKQFLEDPFRPGERIYRTGDLARWLPDGNIEFLGRIDNQ 860 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + KV G+++ EIE L + V E AV+ ++A ICA + Sbjct: 861 V-KVRGFRIELGEIETKLNMAEHVTEAAVIIRKNKADENEICAYFTADRE---------- 909 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + L L Y +P L DSLP GK+N Sbjct: 910 --VAVSELRKTLSQSLPDYMVPAHLIQMDSLPLTPNGKIN 947
>ACSA_MOUSE (Q9QXG4) Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1)| (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) Length = 701 Score = 64.3 bits (155), Expect = 4e-10 Identities = 40/125 (32%), Positives = 62/125 (49%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G++ TGD D+DGY+ I GR + D++ V G+ LS E+E+ L+EH+ V E AV+G P Sbjct: 546 GYYVTGDGCRRDQDGYYWITGRID-DMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPH 604 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRN 176 GE + + + P LT E L ++K+ P P + L + Sbjct: 605 PVKGECLYCFVTLCDG------HTFSPTLT-EELKKQIREKIGPIATPDYIQNAPGLLKP 657 Query: 175 AMGKV 161 GK+ Sbjct: 658 RSGKI 662
>ACS2_CANAL (Q8NJN3) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) (Fragment) Length = 581 Score = 63.9 bits (154), Expect = 5e-10 Identities = 38/103 (36%), Positives = 59/103 (57%), Gaps = 4/103 (3%) Frame = -1 Query: 637 ETKDGVGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGR 470 E D G L IK PS+ + +K +++++ G++ TGD D DGY+ I GR Sbjct: 473 EGNDAEGVLAIKDHWPSMARTVYKNHTKYMDTYMNPYPGYYFTGDGAARDHDGYYWIRGR 532 Query: 469 TNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 + D++ V G++LS EIEA L+E V E AV+G+ D+ G+ Sbjct: 533 VD-DVVNVSGHRLSTAEIEAALIEDKKVSEAAVVGIHDDITGQ 574
>ACSA_RHOBA (P59872) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 671 Score = 63.5 bits (153), Expect = 6e-10 Identities = 35/107 (32%), Positives = 57/107 (53%), Gaps = 4/107 (3%) Frame = -1 Query: 619 GELCIKSP--SLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNADIM 452 G+LCI P + + + E E + + TGD D DGY+ I+GR + D++ Sbjct: 490 GKLCISQPWPGMLRGIYGDEERFVEQYWSDVPDKYLTGDNARCDTDGYYWIMGRID-DVI 548 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE 311 V G++LS +E+E+ L+ H V E AV+G P + G+ I A + + Sbjct: 549 NVSGHRLSTIEVESALVSHPDVCEAAVVGRPHDLKGQAIAAFVTSND 595
>LGRA_BREPA (Q70LM7) Linear gramicidin synthetase subunit A [Includes:| ATP-dependent valine/leucine adenylase (Val/LeuA) (Valine/leucine activase); ATP-dependent glycine adenylase (GlyA) (Glycine activase)] Length = 2273 Score = 63.2 bits (152), Expect = 8e-10 Identities = 50/180 (27%), Positives = 80/180 (44%), Gaps = 7/180 (3%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESF----IDGG--FFKTG 518 P II G GV GELCI SL + Y P +T E F ++ G ++TG Sbjct: 1539 PNYRMYIINRHGQLQPIGVPGELCIAGASLARGYLNNPALTEEKFTPHPLEKGERIYRTG 1598 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D EDG LGR + + K+ GY++ EI + L++ +T+ + V+ D+ Sbjct: 1599 DLARYREDGNIEYLGRMDHQV-KIRGYRIELDEIRSKLIQEETIQDAVVVARNDQNGQAY 1657 Query: 337 ICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +CA ++ +++ T+ L + +L Y IP L P A GK++ Sbjct: 1658 LCAYLLSEQE------------WTVGQLRELLRRELPEYMIPAHFVLLKQFPLTANGKLD 1705 Score = 55.8 bits (133), Expect = 1e-07 Identities = 47/161 (29%), Positives = 72/161 (44%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFI-----DGGFFKTGDTVTVDEDGYFIILGRTNADI 455 GEL I L + Y RPE+TAE FI ++TGD DG LGR + ++ Sbjct: 528 GELFIVGEGLGRGYLNRPELTAEKFIVHPQTGERMYRTGDRARFLPDGNIEFLGRLD-NL 586 Query: 454 MKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE--VICAIIVPKEDARERAEQAS 281 +K+ GY++ EIE L+ H ++E + ++A G ++ + P+E Sbjct: 587 VKIRGYRIEPGEIEPFLMNH-PLIELTTVLAKEQADGRKYLVGYYVAPEE---------- 635 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + L W + L Y IPT + P A GKV+ Sbjct: 636 ---IPHGELREWLGNDLPDYMIPTYFVHMKAFPLTANGKVD 673
>VRAA_STAAW (Q7A1Q0) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = -1 Query: 697 VQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 V+SV L P VE K D +G+G +CIKS +F Y V+ + + +F T Sbjct: 288 VESVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVT 338 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G+ Sbjct: 339 NDNGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQ 396 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 397 I--GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAU (Q9KWK5) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = -1 Query: 697 VQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 V+SV L P VE K D +G+G +CIKS +F Y V+ + + +F T Sbjct: 288 VESVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVT 338 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G+ Sbjct: 339 NDNGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQ 396 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 397 I--GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAS (Q6GBR2) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = -1 Query: 697 VQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 V+SV L P VE K D +G+G +CIKS +F Y V+ + + +F T Sbjct: 288 VESVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVT 338 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G+ Sbjct: 339 NDNGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQ 396 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 397 I--GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAN (Q7A769) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = -1 Query: 697 VQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 V+SV L P VE K D +G+G +CIKS +F Y V+ + + +F T Sbjct: 288 VESVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVT 338 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G+ Sbjct: 339 NDNGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQ 396 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 397 I--GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAM (Q99W34) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = -1 Query: 697 VQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 V+SV L P VE K D +G+G +CIKS +F Y V+ + + +F T Sbjct: 288 VESVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVT 338 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G+ Sbjct: 339 NDNGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQ 396 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 397 I--GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>VRAA_STAAC (Q5HIA1) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 62.8 bits (151), Expect = 1e-09 Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = -1 Query: 697 VQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 V+SV L P VE K D +G+G +CIKS +F Y V+ + + +F T Sbjct: 288 VESVGVLFPNVELKTTNHD----HNGIGTICIKSNMMFSGY-----VSEQCINNDEWFVT 338 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D V E Y + GR D++ +GG + +E +L + ++ E ++G+P+E +G+ Sbjct: 339 NDNGYVKEQ-YLYLTGRQQ-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQ 396 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + +++ D LT + + + K K+ Y+IP+ +H + + A GK+ Sbjct: 397 I--GVLLYSGDV----------TLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKI 444
>ACSA_CRYPV (Q27549) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 694 Score = 62.0 bits (149), Expect = 2e-09 Identities = 49/178 (27%), Positives = 83/178 (46%), Gaps = 8/178 (4%) Frame = -1 Query: 670 VEAKIIMDDGTETKDGVGE--LCIKS--PSLFKEYWKRP---EVTAESFIDGGFFKTGDT 512 +E I+ D + DG G LCIK+ P +F+ + E+ + F ++ TGD Sbjct: 480 IEPAILDPDTGKEIDGPGSGVLCIKNSWPGMFRGIFGAHYLHEIYTKPFPK--YYFTGDG 537 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 332 V D+DGY I GR + D + V G++LS+ EIE L H + E A + + + G + Sbjct: 538 VLRDQDGYLWITGRID-DTINVSGHRLSSKEIEDALTNHFGIAEAAAVAIDHDVKGNALV 596 Query: 331 AIIVPKEDARERAE-QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 +V K+ + S P L + ++ P P + + +++P+ GKV Sbjct: 597 CFVVLKDSGNRTFDLNNSSPHPFEYELRMCVRTQIGPVATPDHIIVVENIPKTRSGKV 654
>ACSA1_PSEAE (Q9I558) Acetyl-coenzyme A synthetase 1 (EC 6.2.1.1) (Acetate--CoA| ligase 1) (Acyl-activating enzyme 1) Length = 651 Score = 62.0 bits (149), Expect = 2e-09 Identities = 35/126 (27%), Positives = 61/126 (48%), Gaps = 1/126 (0%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD DEDGY+ I GR + D++ V G+++ E+E+ ++ H V E AV+G+ Sbjct: 494 GMYFTGDGARRDEDGYYWITGRVD-DVLNVSGHRMGTAEVESAMVAHPKVAEAAVVGMQH 552 Query: 355 EAYGEVICAIIVPKEDARERAEQASKPALTL-EALTSWSKDKLAPYKIPTRLHLWDSLPR 179 + G+ I + +P+ L + L W + ++ P P + LP+ Sbjct: 553 DIKGQGIYVYVT--------LNSGVEPSEALRQELKQWVRREIGPIATPDVIQWAPGLPK 604 Query: 178 NAMGKV 161 GK+ Sbjct: 605 TRSGKI 610
>PKSJ_BACSU (P40806) Putative polyketide synthase pksJ (PKS)| Length = 5045 Score = 61.6 bits (148), Expect = 2e-09 Identities = 45/160 (28%), Positives = 72/160 (45%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELCI + K Y+K+ E+T FID F ++TGD G +GR + Sbjct: 1493 GELCIAGDGVAKGYYKKEELTDSRFIDNPFEPGSKLYRTGDMARWLTGGRIEYIGRIDNQ 1552 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ G+++ +IE+ L EH +LEC V+ D + A K + Sbjct: 1553 V-KIRGFRIELGDIESRLSEHPGILECVVVADMDN-----LAAYYTAKH---------AN 1597 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +LT L + K+ L Y +P+ D +P GK++ Sbjct: 1598 ASLTARELRHFVKNALPAYMVPSYFIQLDHMPLTPNGKID 1637 Score = 40.4 bits (93), Expect = 0.006 Identities = 40/178 (22%), Positives = 78/178 (43%), Gaps = 6/178 (3%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVD 500 P +I+ D ++G +G + S+ Y++RP++ F + G+F+TGD + Sbjct: 381 PGFSMRIVNDHNELVEEGEIGRFQVSGLSVTSGYYQRPDLNESVFTEDGWFETGDLGFL- 439 Query: 499 EDGYFIILGRTNADIMKVGGYKLSALEIEAVL-----LEHDTVLECAVLGLPDEAYGEVI 335 +G I GRT D + + G + IE+ + +E CAV L + ++ Sbjct: 440 RNGRLTITGRTK-DAIIINGINYYSHAIESAVEELPEIETSYTAACAV-RLGQNSTDQLA 497 Query: 334 CAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + A+ EQ S+ +++ S Y +P + + +P+ A+GK+ Sbjct: 498 IFFVT---SAKLNDEQMSQLLRNIQSHVSQVIGVTPEYLLPVQK---EEIPKTAIGKI 549
>SRFAC_BACSU (Q08787) Surfactin synthetase subunit 3| Length = 1274 Score = 61.2 bits (147), Expect = 3e-09 Identities = 48/161 (29%), Positives = 71/161 (44%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGELCI + K Y R ++T E FI+ F ++TGD DG GR + Sbjct: 803 VGELCISGMGVSKGYVNRADLTKEKFIENPFKPGETLYRTGDLARWLPDGTIEYAGRID- 861 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D +K+ G+++ EIE L E+ V + V+ E+ DA A + Sbjct: 862 DQVKIRGHRIELEEIEKQLQEYPGVKDAVVVADRHES------------GDASINAYLVN 909 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + L+ E + + K +L Y +P D LP GKVN Sbjct: 910 RTQLSAEDVKAHLKKQLPAYMVPQTFTFLDELPLTTNGKVN 950
>BACB_BACLI (O68007) Bacitracin synthetase 2 (BA2) [Includes: ATP-dependent| lysine adenylase (LysA) (Lysine activase); ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine activase); Ornithine racemase (EC 5.1.1.12)] Length = 2607 Score = 61.2 bits (147), Expect = 3e-09 Identities = 43/160 (26%), Positives = 70/160 (43%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFID------GGFFKTGDTVTVDEDGYFIILGRTNAD 458 GEL I + + Y +PE+T E F+ G +KTGD DG LGR + Sbjct: 1894 GELYIGGEGIARGYLNKPELTKERFVPNRFAAGGNMYKTGDLARWLPDGNVEFLGRIDHQ 1953 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ G+++ EIE LLE+ + E V+ D+ + +CA IV ++ Sbjct: 1954 V-KIRGFRIETGEIETKLLENQNISEAVVIDREDKKGHKYLCAYIV------------AR 2000 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + D L Y +P+ + +P GK++ Sbjct: 2001 AKTNTNELREYLSDHLPDYMLPSYFIQINKMPLTPNGKID 2040 Score = 50.8 bits (120), Expect = 4e-06 Identities = 43/161 (26%), Positives = 69/161 (42%), Gaps = 7/161 (4%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFI--DGG--FFKTGDTVTVDEDGYFIILGRTNADIM 452 GEL I + + Y +T +F+ + G ++TGD DG LGR ++ + Sbjct: 852 GELLIGGEGVARGYLNHETLTKAAFVVDESGERVYRTGDLARWLSDGNIEFLGRIDSQV- 910 Query: 451 KVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIV---PKEDARERAEQAS 281 K+ GY++ EIE LL +D + E V+ D+ + +CA I D + E+ + Sbjct: 911 KIRGYRIELEEIEHRLLMNDNINEAIVVAKEDQENSKYLCAYIAFNNKNADIEQVQERLA 970 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 K L Y IP+ D +PR GK + Sbjct: 971 K--------------DLPEYMIPSCFIKLDQIPRTINGKAD 997
>DLTA_STRP6 (Q5XBN5) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 61.2 bits (147), Expect = 3e-09 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 491 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ ED Sbjct: 334 IIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDN 393 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 314 + GR + I K GY++ ++ L + V AV E + + A IV K Sbjct: 394 ILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVK 452 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + +ER ++ + +A+ + KD + Y +P++ DSLP GK++ Sbjct: 453 DGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKID 501
>DLTA_STRP3 (Q8K744) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 61.2 bits (147), Expect = 3e-09 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 491 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ ED Sbjct: 334 IIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDN 393 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 314 + GR + I K GY++ ++ L + V AV E + + A IV K Sbjct: 394 ILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVK 452 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + +ER ++ + +A+ + KD + Y +P++ DSLP GK++ Sbjct: 453 DGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKID 501
>DLTA_STRP1 (Q99ZA6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 61.2 bits (147), Expect = 3e-09 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 491 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ ED Sbjct: 334 IIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDN 393 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 314 + GR + I K GY++ ++ L + V AV E + + A IV K Sbjct: 394 ILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVK 452 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + +ER ++ + +A+ + KD + Y +P++ DSLP GK++ Sbjct: 453 DGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKID 501
>ACSA_XYLFT (Q87C00) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 61.2 bits (147), Expect = 3e-09 Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 8/139 (5%) Frame = -1 Query: 553 ESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 392 + FID F + TGD D DGY+ I GR + D++ + G+++ EIE+ L+ H Sbjct: 481 QRFIDTYFRTYPNTYFTGDGCRRDADGYYWITGRVD-DVINISGHRIGTAEIESTLVAHP 539 Query: 391 TVLECAVLGLPDEAYGEVICAII--VPKEDARERAEQASKPALTLEALTSWSKDKLAPYK 218 V E AV+G P G+ I A + + E E Q L +W + ++ Sbjct: 540 KVAEAAVVGFPHPIKGQGIYAYVTLITGETPSEALHQ---------ELLTWVRKEIGAIA 590 Query: 217 IPTRLHLWDSLPRNAMGKV 161 IP + +LP+ GK+ Sbjct: 591 IPDHVQWASNLPKTRSGKI 609
>PPS2_BACSU (P39846) Peptide synthetase 2| Length = 2560 Score = 60.8 bits (146), Expect = 4e-09 Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GEL I + + Y R E+TA+ F+ + ++TGD +G LGR + Sbjct: 1840 GELYIGGEGVARGYLNRDELTADRFVSNPYLPGDRLYRTGDLAKRLSNGELEYLGRIDEQ 1899 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + KV G+++ EI+A LL++ + E AV+ DE I A +V K+ + Sbjct: 1900 V-KVRGHRIELGEIQAALLQYPMIKEAAVITRADEQGQTAIYAYMVIKD----------Q 1948 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 A + + ++ K+ L + +P R+ DS+P GK++ Sbjct: 1949 QAANISDIRTYLKNALPDFMLPARMIQIDSIPVTVNGKLD 1988 Score = 60.1 bits (144), Expect = 7e-09 Identities = 48/160 (30%), Positives = 73/160 (45%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELCI L + Y+K+ E+T ++F D F ++TGD DG +GR + D Sbjct: 802 GELCISGAGLARGYYKQQELTQKAFSDHPFLEGERLYRTGDAGRFLPDGTIEYIGRFD-D 860 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 +K+ GY++ EIE VL + V E AVL A + + A IVP++ Sbjct: 861 QVKIRGYRIELREIETVLRQAPGVKEAAVLARDVSAEEKELVAYIVPEK----------- 909 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +L L L Y IP + +P + GK++ Sbjct: 910 -GNSLPDLYQHLAGTLPSYMIPASIINISQMPLTSSGKLD 948
>VRAA_STAAR (Q6GJ94) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 458 Score = 60.8 bits (146), Expect = 4e-09 Identities = 46/180 (25%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = -1 Query: 697 VQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKT 521 V+SV L P VE K D +G+G +C+KS +F Y V+ + + +F T Sbjct: 288 VESVGVLFPNVELKTTNHD----HNGIGTICVKSNMMFSGY-----VSEQCINNDEWFVT 338 Query: 520 GDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE 341 D V E Y + GR + D++ +GG + +E +L + ++ E ++G+P+E +G+ Sbjct: 339 NDNGYVKEQ-YLYLTGRQH-DMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQ 396 Query: 340 VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + +++ D LT + + + K+ Y+IP+ +H + + A GK+ Sbjct: 397 I--GVLLYSGDV----------TLTHKNVKQFLNKKVKRYEIPSMIHHVEKMYYTASGKI 444
>DLTA_STRP8 (Q8P0J9) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 512 Score = 60.8 bits (146), Expect = 4e-09 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 491 II +DG E G GE+ + P++ K Y PE TAE+F + TGD ++ ED Sbjct: 334 IIDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDN 393 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 314 + GR + I K GY++ ++ L + V AV E + + A IV K Sbjct: 394 ILLYGGRLDFQI-KYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVK 452 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + +ER ++ + +A+ + KD + Y +P++ DSLP GK++ Sbjct: 453 DGVKERFDRELE---LTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKID 501
>PRPE_SALTY (P55912) Propionate--CoA ligase (EC 6.2.1.17) (Propionyl-CoA| synthetase) Length = 628 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/142 (26%), Positives = 68/142 (47%) Frame = -1 Query: 586 KEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAV 407 K YW S + + T D D +GY+ ILGRT+ D++ + G++L EIE Sbjct: 463 KTYW--------SLFNRQVYATFDWGIRDAEGYYFILGRTD-DVINIAGHRLGTREIEES 513 Query: 406 LLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLA 227 + + V E AV+G+ D G+V A ++PK+ +A++ A+ + +++ Sbjct: 514 ISSYPNVAEVAVVGIKDALKGQVAVAFVIPKQSDTLADREAARD--EENAIMALVDNQIG 571 Query: 226 PYKIPTRLHLWDSLPRNAMGKV 161 + P + LP+ GK+ Sbjct: 572 HFGRPAHVWFVSQLPKTRSGKM 593
>ACSA_RHILO (Q98ET8) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 651 Score = 60.1 bits (144), Expect = 7e-09 Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 6/131 (4%) Frame = -1 Query: 535 GFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 G + TGD D DGY+ I GR + D++ V G+++ E+E+ L+ HD V E AV+G P Sbjct: 495 GKYFTGDGCRRDADGYYWITGRVD-DVINVSGHRMGTAEVESALVSHDKVSEAAVVGYPH 553 Query: 355 EAYGEVICAIIV------PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLW 194 + G+ I + + P ED R+ L + + ++ P ++ Sbjct: 554 DIKGQGIYSYVTLMKGEEPTEDLRKE-------------LIAHVRKEIGAIASPDKIQFA 600 Query: 193 DSLPRNAMGKV 161 LP+ GK+ Sbjct: 601 PGLPKTRSGKI 611
>ACSA_AGRRH (Q9KWA3) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 652 Score = 60.1 bits (144), Expect = 7e-09 Identities = 46/162 (28%), Positives = 77/162 (47%), Gaps = 9/162 (5%) Frame = -1 Query: 619 GELCI------KSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNAD 458 G LCI ++ S++ ++ +R T S +G +F TGD D DGY+ I GR + D Sbjct: 462 GNLCIADSWPGQARSVYGDH-ERFIQTYFSTYEGKYF-TGDGCRRDADGYYWITGRVD-D 518 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVI---CAIIVPKEDARERAEQ 287 ++ V G++L E+E+ L+ H V E AV+G P G+ I ++ E + E +Q Sbjct: 519 VLNVSGHRLGTAEVESALVSHHLVSEAAVVGYPHNIKGQGIYCYVTLMAGSEGSEELRQQ 578 Query: 286 ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L + ++ P P ++ LP+ GK+ Sbjct: 579 ----------LVKHVRAEIGPIASPDKIQFAPGLPKTRSGKI 610
>PPS3_BACSU (P39847) Peptide synthetase 3| Length = 2555 Score = 58.9 bits (141), Expect = 2e-08 Identities = 47/161 (29%), Positives = 71/161 (44%), Gaps = 6/161 (3%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNA 461 VGELC+ + + Y RP++T E F+ F ++TGD DG +GR + Sbjct: 1839 VGELCVGGDGVARGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLSDGTIEYVGRID- 1897 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 D +KV GY++ EIE L + D V E AVL + + + I + Sbjct: 1898 DQVKVRGYRVELGEIETALRQIDGVKEAAVLARTAQTGSKELFGYI------------SV 1945 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 K E + S L Y IP + ++LP + GK+N Sbjct: 1946 KAGTNAEQVRSLLARSLPNYMIPAYIIEMETLPLTSNGKLN 1986 Score = 53.1 bits (126), Expect = 8e-07 Identities = 40/116 (34%), Positives = 56/116 (48%), Gaps = 6/116 (5%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFF------KTGDTVTVDEDGYFIILGRTNAD 458 GEL I + + Y RP +T E F++ F+ KTGD DG LGRT+ D Sbjct: 807 GELYIAGAGVARGYLNRPALTEERFLEDPFYLGERMYKTGDVARWLPDGNVEFLGRTD-D 865 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAE 290 +K+ GY++ EIEA L + V E AV D E +CA + + RA+ Sbjct: 866 QVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPE-LCAYVEGLQRNEVRAQ 920
>ACSA_XYLFA (Q9PB89) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 647 Score = 58.9 bits (141), Expect = 2e-08 Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 8/139 (5%) Frame = -1 Query: 553 ESFIDGGF------FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHD 392 + FID F + TGD D DGY+ I GR + D++ + G+++ EIE+ L+ H Sbjct: 481 QRFIDTYFRTYPNTYFTGDGCRRDADGYYWITGRVD-DVINISGHRIGTAEIESTLVAHP 539 Query: 391 TVLECAVLGLPDEAYGEVICAII--VPKEDARERAEQASKPALTLEALTSWSKDKLAPYK 218 V E AV+G P G+ I A + + E E Q L +W + ++ Sbjct: 540 KVAEAAVVGFPHPIKGQGIYAYVTLITGETPSEALHQ---------ELLTWVRKEIGAIA 590 Query: 217 IPTRLHLWDSLPRNAMGKV 161 P + +LP+ GK+ Sbjct: 591 TPDHVQWAPNLPKTRSGKI 609
>ACSA2_PSEPK (Q88DW6) Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA| ligase 2) (Acyl-activating enzyme 2) Length = 644 Score = 58.5 bits (140), Expect = 2e-08 Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 4/159 (2%) Frame = -1 Query: 625 GVGELCIKS--PSLFKEYWKRPEVTAESFIDG--GFFKTGDTVTVDEDGYFIILGRTNAD 458 G G L IK+ P + + + +++ G++ TGD D DG + I GR + D Sbjct: 456 GAGVLAIKASWPGQIRSVYGDHQRMVDTYFKPLPGYYFTGDGARRDADGDYWITGRID-D 514 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 ++ V G+++ E+E+ L+ HD+V E AV+G P + G+ + A + Sbjct: 515 VINVSGHRIGTAEVESALVLHDSVAEAAVVGYPHDLKGQGVYAFVTTMNGV------TPD 568 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 L E L SK+ + + P + +LP+ GK+ Sbjct: 569 DTLKAELLALVSKE-IGSFAKPELIQWAPALPKTRSGKI 606
>PPS1_BACSU (P39845) Peptide synthetase 1| Length = 2561 Score = 57.8 bits (138), Expect = 3e-08 Identities = 51/160 (31%), Positives = 74/160 (46%), Gaps = 6/160 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 GELCI + K Y +P++T F + F ++TGD +G +LGR + Sbjct: 1845 GELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGRMDYQ 1904 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 + K+ GY++ EIE+VLL+ V E AV D+ + A IVP D A +A Sbjct: 1905 V-KINGYRIETEEIESVLLQTGLVREAAVAVQHDKNGQAGLAAYIVP-SDVNTNALRA-- 1960 Query: 277 PALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 ALT E L Y IP L ++P GK++ Sbjct: 1961 -ALTKE---------LPAYMIPAYLIPLVNMPLTLNGKLD 1990 Score = 53.1 bits (126), Expect = 8e-07 Identities = 40/116 (34%), Positives = 56/116 (48%), Gaps = 6/116 (5%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFF------KTGDTVTVDEDGYFIILGRTNAD 458 GEL I + + Y RP +T E F++ F+ KTGD DG LGRT+ D Sbjct: 801 GELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTD-D 859 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAE 290 +K+ GY++ EIEA L + V E AV D E +CA + + RA+ Sbjct: 860 QVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPE-LCAYVEGLQRNEVRAQ 914
>DLTA_LACRH (P35854) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 506 Score = 57.4 bits (137), Expect = 4e-08 Identities = 48/181 (26%), Positives = 82/181 (45%), Gaps = 8/181 (4%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDGG---FFKTGDTV 509 P ++ + G + G GEL I PS+ K Y P+ TA +F G +++GD V Sbjct: 326 PDTNVYVVDEQGEQVSAGTEGELMIVGPSVSKGYLNNPDKTAAAFFKAGNQRGYRSGDLV 385 Query: 508 TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGE---V 338 T+ DG GRT+ + K+ GY++ +++ L + + + + + D+ + + Sbjct: 386 TMTADGMVFYRGRTDFQV-KLHGYRIELEDVDHNLNQVSYIKQASTVPRYDKDHKVAQLI 444 Query: 337 ICAIIVPKE-DARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 A+ P + D+ + QA K L + Y IP R+ D LP A GKV Sbjct: 445 AFAVAKPNDFDSEMKLTQAIKAEL---------GKMVMEYMIPQRIIYRDQLPLTANGKV 495 Query: 160 N 158 + Sbjct: 496 D 496
>DLTA_LACPL (Q88VM6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 508 Score = 57.0 bits (136), Expect = 6e-08 Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESF--IDG-GFFKTGDTVTVDEDG 491 ++ ++G +G GEL I PS+ K Y E TA++F +DG + +GD T+D DG Sbjct: 333 VVDENGEAVPNGTEGELIIAGPSVSKGYLNNSEKTAKAFFELDGQPAYHSGDIGTMDADG 392 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV-ICAIIVPK 314 F GR + I K+ GY++ E++ L + + + + D+ + + A +VPK Sbjct: 393 LFRYRGRVDFQI-KMHGYRIELEEVDHFLAQQQHIKQAVAVPKYDKEHKVTQMIAYVVPK 451 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + E S ALT A+ + + Y IP R SLP GK++ Sbjct: 452 PNDFE-----SDFALT-TAIKKDLQGMMMEYMIPQRFVYQTSLPLTPNGKID 497
>VRAA_STAEQ (Q5HRH4) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 453 Score = 55.8 bits (133), Expect = 1e-07 Identities = 44/174 (25%), Positives = 83/174 (47%) Frame = -1 Query: 682 LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTV 503 L P VE +++ D D VG L ++S +F Y +S +G + KTGD + Sbjct: 290 LFPHVETRLLNQDD----DAVGLLAVRSEMVFSGY------VGQSNQEGSWIKTGDFAYI 339 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 F++ GR +D + VGG + IE+++++ + + E V+G+P +GE+ AI+ Sbjct: 340 KNQHLFLV-GR-ESDRIIVGGINVYPTAIESLIMDIEGIDEALVIGIPHAKFGEI--AIL 395 Query: 322 VPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 + + K L + S+ +L+ ++P++L D + GK+ Sbjct: 396 L----------YSGKVQLNYRQIKSFLMKQLSRQEVPSKLKKIDHMIYTESGKI 439
>DLTA_STRR6 (P0A399) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 54.7 bits (130), Expect = 3e-07 Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 7/174 (4%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 491 II ++G + +G GE+ + P++ K Y PE TAE+F D + TGD T+ ++G Sbjct: 338 IIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEG 397 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP---DEAYGEVICAIIV 320 + GR + I K GY++ LE + L +E AV +P + + + A ++ Sbjct: 398 LLLYGGRMDFQI-KFNGYRIE-LEDVSQNLNKSRFIESAV-AVPRYNKDHKVQNLLAYVI 454 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 K+ RE+ E + +A+ D + Y +P++ DSLP GK++ Sbjct: 455 LKDGVREQFE---RDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKID 505
>DLTA_STRPN (P0A398) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 54.7 bits (130), Expect = 3e-07 Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 7/174 (4%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDEDG 491 II ++G + +G GE+ + P++ K Y PE TAE+F D + TGD T+ ++G Sbjct: 338 IIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGTMTDEG 397 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP---DEAYGEVICAIIV 320 + GR + I K GY++ LE + L +E AV +P + + + A ++ Sbjct: 398 LLLYGGRMDFQI-KFNGYRIE-LEDVSQNLNKSRFIESAV-AVPRYNKDHKVQNLLAYVI 454 Query: 319 PKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 K+ RE+ E + +A+ D + Y +P++ DSLP GK++ Sbjct: 455 LKDGVREQFE---RDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKID 505
>DLTA_BACSU (P39581) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 503 Score = 54.7 bits (130), Expect = 3e-07 Identities = 50/177 (28%), Positives = 83/177 (46%), Gaps = 4/177 (2%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI--DGGF-FKTGDTV 509 P + I+ ++G +G GE+ I PS+ + Y PE+T ++F +G + ++TGD Sbjct: 325 PDMNIFIMDEEGQPLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFFSHEGQWAYRTGDAG 384 Query: 508 TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICA 329 + +DG GR + I K+ GY++ EIE + + V V+ E + A Sbjct: 385 FI-QDGQIFCQGRLDFQI-KLHGYRMELEEIEFHVRQSQYVRSAVVIPYQPNGTVEYLIA 442 Query: 328 IIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 IVP+E E+ Q + A+ E S L Y IP + D + A GK++ Sbjct: 443 AIVPEEHEFEKEFQLTS-AIKKELAAS-----LPAYMIPRKFIYQDHIQMTANGKID 493
>ACSA_PRB01 (Q9F7R5) Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA| ligase) (Acyl-activating enzyme) Length = 641 Score = 53.9 bits (128), Expect = 5e-07 Identities = 28/67 (41%), Positives = 39/67 (58%) Frame = -1 Query: 523 TGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG 344 TGD DEDGYF I GR + D++ V G++L EIE+ L+ H + E AV+G G Sbjct: 491 TGDGARRDEDGYFWITGRVD-DVLNVSGHRLGTAEIESALVLHPKIAEAAVVGFDHPIKG 549 Query: 343 EVICAII 323 + I A + Sbjct: 550 QGIYAFV 556
>DLTA_STAAW (P68878) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAU (P68877) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAS (Q6GAZ4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAR (Q6GIF6) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAN (P99107) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAM (P68876) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>DLTA_STAAC (Q5HHF2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 53.9 bits (128), Expect = 5e-07 Identities = 46/157 (29%), Positives = 71/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESF-IDGGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K + TAE F D G + TGD E+G + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKF-ENGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + IVP + + AE Sbjct: 386 LNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKN--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + + K +L Y IP + + LP + GK++ Sbjct: 443 ----IKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKID 475
>SID2_USTMA (O43103) Ferrichrome siderophore peptide synthetase (EC 6.-.-.-)| Length = 3947 Score = 53.9 bits (128), Expect = 5e-07 Identities = 42/166 (25%), Positives = 72/166 (43%), Gaps = 8/166 (4%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFID----GGFFKTGDTVTVDEDGYFIILGRTN 464 K VGEL + P L + Y P TA+ F G ++TGD V ++ F LGR + Sbjct: 603 KGAVGELVLGGPQLARGYVGDPVKTADKFFPHPQLGRVYRTGDLVRQLDNQEFEYLGRID 662 Query: 463 ADIMKVGGYKLSALEIEAVLLE-HDTVLECAVLGLP---DEAYGEVICAIIVPKEDARER 296 D +K+ G ++ LEI A + HD + + + +E+ ++I +P + + Sbjct: 663 -DQVKINGIRIELLEINAAIKNSHDKIKDSETMAFSKKDNESEQQIINFSALPGGEPGQL 721 Query: 295 AEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L + +KD L Y +P + PR + K++ Sbjct: 722 LRTDQDAIAVARELQANAKDSLPSYMVPNLFVILSHFPRTSSAKID 767 Score = 40.4 bits (93), Expect = 0.006 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 10/148 (6%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFI---DG-GFFKTGDTVTVDEDGYFIILGRTNAD- 458 +GEL + P L Y+ R E+TAE FI DG ++TGD D LGR +D Sbjct: 2822 IGELAVGGPQLADCYYGREELTAEKFILLEDGTRVYRTGDLGRFLVDDTVECLGRIGSDR 2881 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYG--EVICAIIVPKEDARERAEQA 284 +KV G ++ E+ +V+ V + V L + G +++ + + A++ Sbjct: 2882 QVKVNGQRMELDEVCSVISAQAGVYDADVQYLKHPSMGSKQLVAFVAAAETQAKQGDMDV 2941 Query: 283 SKPALTLE---ALTSWSKDKLAPYKIPT 209 ++ L + +LA Y +PT Sbjct: 2942 RDDDKAIDLCIRLEQEAAKRLATYMVPT 2969 Score = 35.0 bits (79), Expect = 0.24 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGG-FFKTGDTVTVDEDGYFIILGRTNADIMKVG 443 GEL I + K Y RP+ ++ G ++TGD V + LGR + +KV Sbjct: 1745 GELYIGGEQVAKGYLNRPDSSSFITYQGQQIYRTGDMVRLHPSDEAEYLGRIDGSQVKVR 1804 Query: 442 GYKLSALEIEAVL 404 G +L E++A L Sbjct: 1805 GARLELAEVDAAL 1817
>HTS1_COCCA (Q01886) HC-toxin synthetase (EC 6.3.2.-) (HTS)| Length = 5218 Score = 53.1 bits (126), Expect = 8e-07 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 26/181 (14%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDG----------------GFFKTGDTVTVDEDG 491 +GEL I+S L +Y RP+ T +F+ F++TGD V +DG Sbjct: 547 IGELLIESGHLADKYLNRPDRTEAAFLSDLPWIPNYEGDSVRRGRRFYRTGDLVRYCDDG 606 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVL---GLPDEAYGEVICAIIV 320 I +GR++ I K+ G ++ ++EA L T + AV+ P EA +I ++ Sbjct: 607 SLICVGRSDTQI-KLAGQRVELGDVEAHLQSDPTTSQAAVVFPRSGPLEA--RLIALLVT 663 Query: 319 PKEDARERAEQA-SKPALT------LEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 +D +Q+ KPA ++ TS + +L Y +P+ D LP + GK+ Sbjct: 664 GNKDGTPHNQQSLPKPAFAQCPPDLVKYATSSLQQRLPSYMVPSVWLGIDFLPMSVSGKL 723 Query: 160 N 158 + Sbjct: 724 D 724 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESF----IDG-------GFFKTGDTVTVDEDGYFIIL 476 VGELCI++PSL + Y PE T SF +D ++TGD V DG L Sbjct: 3317 VGELCIEAPSLARCYLANPERTEYSFPSTVLDNWQTKKGTRVYRTGDLVRYASDGTLDFL 3376 Query: 475 GRTNADIMKVGGYKLSALEIE 413 GR + I K+ G ++ EIE Sbjct: 3377 GRKDGQI-KLRGQRIELGEIE 3396 Score = 42.7 bits (99), Expect = 0.001 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 11/84 (13%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFI-----------DGGFFKTGDTVTVDEDGYFIIL 476 VGEL I+ L + Y PE TAE FI + +KTGD V DG I + Sbjct: 2165 VGELIIEGSILCRGYLNDPERTAEVFIRSPSWLHDLRPNSTLYKTGDLVRYSADGKIIFI 2224 Query: 475 GRTNADIMKVGGYKLSALEIEAVL 404 GR + + K+ G + E+E L Sbjct: 2225 GRKDTQV-KMNGQRFELGEVEHAL 2247 Score = 31.6 bits (70), Expect = 2.6 Identities = 30/126 (23%), Positives = 52/126 (41%), Gaps = 34/126 (26%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDG-----GF-----------FKTGDTVTVDEDGY 488 GEL I+ P++ + Y +T+++FI G+ +KTGD V Sbjct: 4462 GELYIQGPTVARGYLHDDVLTSKAFIVDPQWLTGYKTNENQWSRRAYKTGDLVFWGPQSN 4521 Query: 487 FIILGRTNADIMKVGGYKLSALEIEAVLLEH------------------DTVLECAVLGL 362 + R ++ +K+ G ++ EIE V+ +H ++ AVLG+ Sbjct: 4522 LYYVRRKDSSQVKIRGQRVELAEIEEVIRQHIPPDVTVCVDLLSSDDQNTRIILGAVLGI 4581 Query: 361 PDEAYG 344 D A G Sbjct: 4582 GDRALG 4587
>FAD11_MYCTU (Q10776) Putative fatty-acid--CoA ligase fadD11 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 571 Score = 52.4 bits (124), Expect = 1e-06 Identities = 30/94 (31%), Positives = 43/94 (45%) Frame = -1 Query: 682 LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTV 503 L P ++ KI D GE ++ P + K Y K P TAE+ G+ TGD + Sbjct: 354 LLPGLQGKIAED---------GEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDVFDI 404 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLL 401 D DGY ++ R I+ G +S IE +L Sbjct: 405 DSDGYLRVVDRKKELIINAAGKNMSPANIENTIL 438
>DLTA_STAEQ (Q5HQN0) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 52.4 bits (124), Expect = 1e-06 Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 5/159 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAE--SFIDG-GFFKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K E TA +F DG + TGD + EDG + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNEEKTAAVFNFEDGVRTYHTGDKAKI-EDGLWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI--IVPKEDARERAEQASKP 275 + GY++ EIE L + V E V +P G+V+ I +VP E + ++ Sbjct: 386 LNGYRMELEEIETQLRQSKHVREAVV--VPVYKNGKVVHLIGAVVPTESVEDNLAMTTQI 443 Query: 274 ALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L K +L Y IP + + LP GK++ Sbjct: 444 KHEL-------KSRLPEYMIPRKFEWMERLPLTLNGKLD 475
>LCFH_HAEIN (P44446) Putative long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase) (LACS) Length = 607 Score = 52.0 bits (123), Expect = 2e-06 Identities = 38/128 (29%), Positives = 60/128 (46%) Frame = -1 Query: 682 LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTV 503 L P+ E KI ++ E+ ++ + K Y+K+PE TA++F + GF KTGD Sbjct: 405 LMPKAEVKIGENN---------EILVRGGMVMKGYYKKPEETAQAFTEDGFLKTGDAGEF 455 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAII 323 DE G I R ++MK K A + + D +E + + Y + A+I Sbjct: 456 DEQGNLFITDRIK-ELMKTSNGKYIAPQYIESKIGKDKFIEQIAIIADAKKY---VSALI 511 Query: 322 VPKEDARE 299 VP D+ E Sbjct: 512 VPCFDSLE 519
>DLTA_STAHJ (Q4L4U5) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 52.0 bits (123), Expect = 2e-06 Identities = 46/157 (29%), Positives = 72/157 (45%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAE--SFIDG-GFFKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL IK S+ Y E T +F DG + TGD +++DG + I GR + I K Sbjct: 328 GELVIKGNSVSLGYLDNKEKTDAVFNFEDGLRIYHTGDKA-IEKDGQWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ EIE L + + V E V+ + + +VP E+ R+ E + Sbjct: 386 LNGYRMELEEIETQLRQSEFVRETVVVPVYKNNKVIHLIGAVVPTEEVRDDLEMTRQ--- 442 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + S K +L Y IP + LP + GK++ Sbjct: 443 ----IKSELKSRLPEYMIPRKFVWMKQLPLTSNGKLD 475
>VRAA_STAES (Q8CQ67) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 411 Score = 51.2 bits (121), Expect = 3e-06 Identities = 33/115 (28%), Positives = 59/115 (51%) Frame = -1 Query: 682 LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTV 503 L P VE +++ D D VG L ++S +F Y +S +G + KTGD + Sbjct: 290 LFPHVETRLLNQDD----DAVGLLAVRSEMVFSGY------VGQSNQEGAWIKTGDFAYI 339 Query: 502 DEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 F++ GR +D + VGG + IE+++++ + + E V+G+P +GE+ Sbjct: 340 KNQHLFLV-GR-ESDRIIVGGINVYPTAIESLIMDIEGIDEALVIGIPHAKFGEI 392
>DLTA_LISMF (Q721J2) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 51.2 bits (121), Expect = 3e-06 Identities = 41/157 (26%), Positives = 74/157 (47%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GE+ + S+ K Y PE T + F D G+ ++TGD+ + +DGY GR + I K Sbjct: 352 GEIVLIGASVSKGYLNEPEKTDQVFFDYKGYQAYRTGDSGII-KDGYLFFQGRLDFQI-K 409 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ +IE L + + CA++ + +++ A ++P E+ Q S Sbjct: 410 LHGYRIELEDIENNLKKVSYIQNCAIIPKMKDEKVDMLVAQVIPTNHDFEKEYQLS---- 465 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 A+ + K+ + Y IP + P GK++ Sbjct: 466 --AAIKNELKEFMPAYMIPRKWIYKTEFPLTMNGKID 500
>ANGR_VIBAN (P19828) Protein angR| Length = 1048 Score = 51.2 bits (121), Expect = 3e-06 Identities = 51/177 (28%), Positives = 80/177 (45%), Gaps = 4/177 (2%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESF--IDG-GFFKTGDTV 509 PR + +++ D G + D V GEL I + Y+ T F IDG +++TGD Sbjct: 775 PRQQYRVVDDLGRDCPDWVAGELWIGGDGIALGYFDDELKTQAQFLHIDGHAWYRTGDMG 834 Query: 508 TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICA 329 DG LGR + + KVGGY++ EIE L V + + ++ + + A Sbjct: 835 CYWPDGTLEFLGRRDKQV-KVGGYRIELGEIEVALNNIPGVQRAVAIAVGNK--DKTLAA 891 Query: 328 IIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 IV E+A + P L E + +L Y +P R+ ++ P A GKV+ Sbjct: 892 FIVMDS---EQAPIVTAP-LDAEEVQLLLNKQLPNYMVPKRIIFLETFPLTANGKVD 944
>DLTA_STAES (Q8CT93) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 485 Score = 51.2 bits (121), Expect = 3e-06 Identities = 50/159 (31%), Positives = 72/159 (45%), Gaps = 5/159 (3%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAE--SFIDG-GFFKTGDTVTVDEDGYFIILGRTNADIMK 449 GEL I+ S+ Y K E T +F DG + TGD + EDG + I GR + I K Sbjct: 328 GELVIEGQSVSLGYLKNEEKTTAVFNFEDGVRTYHTGDKAKI-EDGLWFIQGRIDFQI-K 385 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI--IVPKEDARERAEQASKP 275 + GY++ EIE L + V E V +P G+VI I +VP E + + Sbjct: 386 LNGYRMELEEIETQLRQSKHVREAVV--VPVYKNGKVIHLIGAVVPTEPVEDNLAMTTHI 443 Query: 274 ALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 L K +L Y IP + + LP + GK++ Sbjct: 444 KHEL-------KSRLPEYMIPRKFEWMEQLPLTSNGKLD 475
>DLTA_LISIN (Q92D47) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 50.8 bits (120), Expect = 4e-06 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GE+ + S+ K Y PE T + F D G+ + TGD+ + +DGY GR + I K Sbjct: 352 GEIILIGASVSKGYLNEPEKTDQVFFDYKGYQAYHTGDSGVI-KDGYLFFQGRLDFQI-K 409 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ +IE L + + CA++ + +++ A ++P E+ Q S Sbjct: 410 LHGYRIELEDIENNLKKVSYIQNCAIIPKMKDEKVDMLVAQVIPSSHDFEKEYQLS---- 465 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 A+ + K+ + Y IP + P GK++ Sbjct: 466 --AAIKNELKEFMPAYMIPRKWIYKTEFPLTMNGKID 500
>ACSL1_CAVPO (Q9JID6) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase) Length = 698 Score = 50.8 bits (120), Expect = 4e-06 Identities = 37/116 (31%), Positives = 55/116 (47%) Frame = -1 Query: 625 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKV 446 G GE+C+K P++FK Y K P TAE+ G+ TGD +G I+ R Sbjct: 504 GEGEVCVKGPNVFKGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 563 Query: 445 GGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASK 278 G ++ +IE + + + V + V G E+ + AI+VP DA A A K Sbjct: 564 QGEYIAPEKIENIYVRSEPVAQVFVHG---ESLQAFLIAIVVP--DAESLASWARK 614
>ACVS_NOCLA (P27743) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3649 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 10/99 (10%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----------FKTGDTVTVDEDGYFIILG 473 VGEL + + + Y RPE+T E F+ F ++TGD V DG LG Sbjct: 2735 VGELYLAGDCVTEGYLHRPELTRERFLPNPFAAESGRFPMIYRTGDVVRRGPDGELQYLG 2794 Query: 472 RTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 R +A + K+ G ++ E+EA L V +CAV+ D Sbjct: 2795 RNDAQV-KINGLRIEPGEVEAALAGCSGVRQCAVVAGAD 2832 Score = 48.1 bits (113), Expect = 3e-05 Identities = 40/170 (23%), Positives = 71/170 (41%), Gaps = 14/170 (8%) Frame = -1 Query: 625 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGY 488 G+GEL I + + Y R ++TA+ F++ F +KTGD V +G Sbjct: 1684 GIGELYIGGIGVTRGYLNREDLTADRFVENPFQTAEERRLGENGRLYKTGDLVRWLPNGE 1743 Query: 487 FIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKED 308 LGRT+ + K+ G ++ E+EA L + V+ V+ + + V +++ Sbjct: 1744 VEYLGRTDLQV-KIRGQRVELGEVEAALSSYPGVVRSLVVAREHAVGQKYLVGFYVGEQE 1802 Query: 307 ARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 E + L W + KL +P R+ +P GK++ Sbjct: 1803 FDE------------QDLKQWMRKKLPESVVPARVLRITDIPVTPSGKLD 1840 Score = 45.1 bits (105), Expect = 2e-04 Identities = 45/169 (26%), Positives = 71/169 (42%), Gaps = 14/169 (8%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFI--------------DGGFFKTGDTVTVDEDGYF 485 +GEL I + Y R ++TAE F +G ++TGD V +G Sbjct: 597 IGELYIGGCGVAPGYLNRDDLTAERFTANPFQTEEEKARGRNGRLYRTGDLARVLLNGEV 656 Query: 484 IILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDA 305 +GR + + K+ G ++ EIEA E V +C V+ + A G+ ED Sbjct: 657 EFMGRADFQL-KLNGVRVEPGEIEAQATEFPGVKKCVVVA-KENATGDRHLVGYYLVEDG 714 Query: 304 RERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 E AE L ++ + +L +P R+ S+P N GKV+ Sbjct: 715 AEVAEAD---------LIAFLEQRLIRIMVPARMVRLTSIPVNVNGKVD 754
>DLTA_LISMO (Q8Y8D4) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 510 Score = 50.4 bits (119), Expect = 5e-06 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 3/157 (1%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFID-GGF--FKTGDTVTVDEDGYFIILGRTNADIMK 449 GE+ + S+ K Y PE T + F D G+ ++TGD+ + +DGY GR + I K Sbjct: 352 GEIVLIGASVSKGYLNEPEKTDQVFFDYKGYQAYRTGDSGII-KDGYLFFQGRLDFQI-K 409 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPAL 269 + GY++ +IE L + + CA++ + +++ A ++P E+ Q S Sbjct: 410 LHGYRIELEDIENNLKKVSYIQNCAIIPKMKDEKVDMLVAQVIPTTHDFEKEYQLS---- 465 Query: 268 TLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 A+ K+ + Y IP + P GK++ Sbjct: 466 --AAIKKELKEFMPAYMIPRKWIYKTDFPLTMNGKID 500
>LCF4_YEAST (P47912) Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 4) (Fatty acid activator 4) Length = 694 Score = 49.7 bits (117), Expect = 9e-06 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 2/95 (2%) Frame = -1 Query: 685 NLXPRVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDT 512 +L + AK++ D G K+ GEL K + EY+K PE TA +F D G+F+TGD Sbjct: 476 DLVGTITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKNPEETAAAFTDDGWFRTGDI 535 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAV 407 G I+ R + + G ++ ++E++ Sbjct: 536 AEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESI 570
>ACVS2_PENCH (P26046) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3791 Score = 49.3 bits (116), Expect = 1e-05 Identities = 49/190 (25%), Positives = 79/190 (41%), Gaps = 23/190 (12%) Frame = -1 Query: 658 IIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FK 524 ++ +D T G VGEL + + + Y R +VTAE FI F +K Sbjct: 1746 VLNEDMKRTPIGAVGELYLGGEGVVRGYHNRADVTAERFIPNPFQSEEDKREGRNSRLYK 1805 Query: 523 TGDTV--TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 350 TGD V G LGR + + K+ G ++ EIEA+L + + + V+ Sbjct: 1806 TGDLVRWIPGSSGEVEYLGRNDFQV-KIRGLRIELGEIEAILSSYHGIKQSVVIA----- 1859 Query: 349 YGEVICAIIVPKEDARERAEQ------ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 188 +D RE A++ + AL A+ + + +L Y +P+RL L Sbjct: 1860 ------------KDCREGAQKFLVGYYVADAALPSAAIRRFMQSRLPGYMVPSRLILVSK 1907 Query: 187 LPRNAMGKVN 158 P GK++ Sbjct: 1908 FPVTPSGKLD 1917 Score = 47.0 bits (110), Expect = 6e-05 Identities = 49/173 (28%), Positives = 68/173 (39%), Gaps = 19/173 (10%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFI 482 GEL I + K Y RPE+T FI F +KTGD +G Sbjct: 670 GELHIGGLGISKGYLNRPELTPHRFIPNPFQTDCEKQLGINSLMYKTGDLARWLPNGEVE 729 Query: 481 ILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL-----PDEAYGEVICAIIVP 317 LGR + I K+ G ++ EIE +L + V V+ P+E E + V Sbjct: 730 YLGRADFQI-KLRGIRIEPGEIETMLAMYPRVRTSLVVSKKLRNGPEETTNEHLVGYYVC 788 Query: 316 KEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + A+ L S+ + KL Y IPTRL +P N GK + Sbjct: 789 DSASVSEAD-----------LLSFLEKKLPRYMIPTRLVQLSQIPVNVNGKAD 830
>ACVS1_PENCH (P19787) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3746 Score = 49.3 bits (116), Expect = 1e-05 Identities = 49/190 (25%), Positives = 79/190 (41%), Gaps = 23/190 (12%) Frame = -1 Query: 658 IIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FK 524 ++ +D T G VGEL + + + Y R +VTAE FI F +K Sbjct: 1714 VLNEDMKRTPIGSVGELYLGGEGVVRGYHNRADVTAERFIPNPFQSEEDKREGRNSRLYK 1773 Query: 523 TGDTV--TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 350 TGD V G LGR + + K+ G ++ EIEA+L + + + V+ Sbjct: 1774 TGDLVRWIPGSSGEVEYLGRNDFQV-KIRGLRIELGEIEAILSSYHGIKQSVVIA----- 1827 Query: 349 YGEVICAIIVPKEDARERAEQ------ASKPALTLEALTSWSKDKLAPYKIPTRLHLWDS 188 +D RE A++ + AL A+ + + +L Y +P+RL L Sbjct: 1828 ------------KDCREGAQKFLVGYYVADAALPSAAIRRFMQSRLPGYMVPSRLILVSK 1875 Query: 187 LPRNAMGKVN 158 P GK++ Sbjct: 1876 FPVTPSGKLD 1885 Score = 47.0 bits (110), Expect = 6e-05 Identities = 49/173 (28%), Positives = 68/173 (39%), Gaps = 19/173 (10%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFI 482 GEL I + K Y RPE+T FI F +KTGD +G Sbjct: 640 GELHIGGLGISKGYLNRPELTPHRFIPNPFQTDCEKQLGINSLMYKTGDLARWLPNGEVE 699 Query: 481 ILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGL-----PDEAYGEVICAIIVP 317 LGR + I K+ G ++ EIE +L + V V+ P+E E + V Sbjct: 700 YLGRADFQI-KLRGIRIEPGEIETMLAMYPRVRTSLVVSKKLRNGPEETTNEHLVGYYVC 758 Query: 316 KEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + A+ L S+ + KL Y IPTRL +P N GK + Sbjct: 759 DSASVSEAD-----------LLSFLEKKLPRYMIPTRLVQLSQIPVNVNGKAD 800
>AAS_YERPS (Q667F1) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 48.9 bits (115), Expect = 2e-05 Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 10/151 (6%) Frame = -1 Query: 700 KVQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------TAE 551 KV +V + P +EA++I G G L ++ P++ + Y + P V A+ Sbjct: 529 KVNTVGRILPGMEARLINVPGIAQG---GRLQLRGPNIMRGYLRVENPGVLEQPSAENAQ 585 Query: 550 SFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAV 371 +D ++ TGD VT+DE G+ I GR K+ G +S +E + + + A Sbjct: 586 GELDANWYDTGDIVTLDEQGFCAIRGRVKR-FAKLAGEMVSLESVEQLAISLSPEGQHAA 644 Query: 370 LGLPDEAYGEVICAIIVPKEDARERAEQASK 278 D A GE + E RER +A++ Sbjct: 645 AAKTDSAKGEALVLFTTDSEITRERLIKAAR 675
>LCF3_YEAST (P39002) Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 3) (Fatty acid activator 3) Length = 694 Score = 48.5 bits (114), Expect = 2e-05 Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 2/125 (1%) Frame = -1 Query: 685 NLXPRVEAKII--MDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDT 512 +L V AK++ D G K+ GEL +K + EY+K P TA SF G+F+TGD Sbjct: 476 DLVGSVTAKLVDVKDLGYYAKNNQGELLLKGAPVCSEYYKNPIETAVSFTYDGWFRTGDI 535 Query: 511 VTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVIC 332 V G I+ R + + G ++ ++E+V + V V DE+ + + Sbjct: 536 VEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYA--DESRVKPV- 592 Query: 331 AIIVP 317 I+VP Sbjct: 593 GIVVP 597
>ACSL1_HUMAN (P33121) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Acyl-CoA synthetase 1) (ACS1) (Pa Length = 698 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/104 (29%), Positives = 51/104 (49%) Frame = -1 Query: 628 DGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMK 449 +G GE+C+K P++F+ Y K P TAE+ G+ TGD +G I+ R Sbjct: 503 EGEGEVCVKGPNVFQGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKL 562 Query: 448 VGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 G ++ +IE + + + V + V G E+ + AI+VP Sbjct: 563 AQGEYIAPEKIENIYMRSEPVAQVFVHG---ESLQAFLIAIVVP 603
>DLTA_STRA5 (P59591) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 48.5 bits (114), Expect = 2e-05 Identities = 45/172 (26%), Positives = 80/172 (46%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDG 491 +I ++G + +G GE+ I P++ K Y PE TAE+F + TGD ++ ++G Sbjct: 334 VIDEEGHKLPNGEQGEIIIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEG 393 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 314 + GR + I K GY++ ++ L + V AV + + + A IV K Sbjct: 394 LLLYGGRMDFQI-KFNGYRIELEDVSQNLNKSQYVKSAVAVPRYNKDHKVQNLLAYIVLK 452 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 E R+ E + +A+ KD + Y +P++ + LP GK++ Sbjct: 453 EGVRDDFE---RDLDLTKAIKEDLKDIMMDYMMPSKFIYREDLPLTPNGKID 501
>DLTA_STRA3 (Q8VM67) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 511 Score = 48.5 bits (114), Expect = 2e-05 Identities = 45/172 (26%), Positives = 80/172 (46%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDG 491 +I ++G + +G GE+ I P++ K Y PE TAE+F + TGD ++ ++G Sbjct: 334 VIDEEGHKLPNGEQGEIIIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEG 393 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 314 + GR + I K GY++ ++ L + V AV + + + A IV K Sbjct: 394 LLLYGGRMDFQI-KFNGYRIELEDVSQNLNKSQYVKSAVAVPRYNKDHKVQNLLAYIVLK 452 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 E R+ E + +A+ KD + Y +P++ + LP GK++ Sbjct: 453 EGVRDDFE---RDLDLTKAIKEDLKDIMMDYMMPSKFIYREDLPLTPNGKID 501
>MENE_ECOLI (P37353) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 451 Score = 47.8 bits (112), Expect = 4e-05 Identities = 38/154 (24%), Positives = 74/154 (48%) Frame = -1 Query: 643 GTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 464 G E K E+ +++ S+ + YW+ ++ + D G++ T D + +G I+GR + Sbjct: 295 GREVKIVNNEVWLRAASMAEGYWRNGQLVS-LVNDEGWYATRDRGEM-HNGKLTIVGRLD 352 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 ++ GG + E+E V+ H VL+ ++ + D+ +G A++ ++ + Sbjct: 353 -NLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGHRPVAVMEYDHESVD----- 406 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 182 L+ W KDKLA ++ P R W +LP Sbjct: 407 ---------LSEWVKDKLARFQQPVR---WLTLP 428
>ACSL1_RAT (P18163) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain-fatty-acid--CoA ligase, liver isozyme) Length = 699 Score = 47.8 bits (112), Expect = 4e-05 Identities = 33/113 (29%), Positives = 52/113 (46%) Frame = -1 Query: 655 IMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIIL 476 + D + G GE+C+K ++FK Y K P TAE+ G+ TGD +G I+ Sbjct: 495 VEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKII 554 Query: 475 GRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 R G ++ +IE + L + V + V G E+ + AI+VP Sbjct: 555 DRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHG---ESLQAFLIAIVVP 604
>LCF2_YEAST (P39518) Long-chain-fatty-acid--CoA ligase 2 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 2) (Fatty acid activator 2) Length = 744 Score = 47.8 bits (112), Expect = 4e-05 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 1/135 (0%) Frame = -1 Query: 631 KDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIM 452 KD GEL I+ P +F+ Y+K P T+++ G+F TGD +D G ++ R Sbjct: 536 KDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRISVIDRVKNFFK 595 Query: 451 KVGGYKLSALEIEAVLLEH-DTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKP 275 G ++ +IE + L + + V G P + + + I+ DA + A P Sbjct: 596 LAHGEYIAPEKIENIYLSSCPYITQIFVFGDPLKTF---LVGIVGVDVDAAQPILAAKHP 652 Query: 274 ALTLEALTSWSKDKL 230 + +W+K+ L Sbjct: 653 -----EVKTWTKEVL 662
>ORA_PLAFN (P16405) Octapeptide-repeat antigen (ORA) (Fragment)| Length = 701 Score = 47.8 bits (112), Expect = 4e-05 Identities = 22/51 (43%), Positives = 32/51 (62%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRT 467 GEL IKS S+F Y+ E T +F + G+FKTGD V ++++G L R+ Sbjct: 436 GELLIKSDSMFSGYFLEKESTEHAFTNDGYFKTGDIVQINDNGSLTFLDRS 486
>AAS_YERPE (Q74RZ6) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 718 Score = 47.4 bits (111), Expect = 5e-05 Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 10/145 (6%) Frame = -1 Query: 700 KVQSVN-LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------TAE 551 KV +V + P +EA++I G G L ++ P++ + Y + P V A+ Sbjct: 529 KVNTVGRILPGMEARLINVPGIAQG---GRLQLRGPNIMRGYLRVENPGVLEQPSAENAQ 585 Query: 550 SFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAV 371 +D ++ TGD VT+DE G+ I GR K+ G +S +E + + + A Sbjct: 586 GELDANWYDTGDIVTLDEQGFCAIRGRVKR-FAKLAGEMVSLESVEQLAISLSPEGQHAA 644 Query: 370 LGLPDEAYGEVICAIIVPKEDARER 296 D A GE + E RER Sbjct: 645 AAKTDSAKGEALVLFTTDSEITRER 669
>DLTA_STRMU (Q53526) D-alanine--poly(phosphoribitol) ligase subunit 1 (EC| 6.1.1.13) (D-alanine-activating enzyme) (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL) Length = 516 Score = 46.6 bits (109), Expect = 8e-05 Identities = 42/172 (24%), Positives = 80/172 (46%), Gaps = 5/172 (2%) Frame = -1 Query: 658 IIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFIDG---GFFKTGDTVTVDEDG 491 II + G + +G GE+ + P++ K Y PE TA +F + + TGD ++ ++G Sbjct: 338 IIDESGHKLANGQQGEIIVSGPAVSKGYLNNPERTAAAFFEFEGLPAYHTGDLGSMTDEG 397 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLEC-AVLGLPDEAYGEVICAIIVPK 314 + GR + I K GY++ E+ L + + AV + + + A +V K Sbjct: 398 LLLYGGRMDFQI-KFNGYRIELEEVSQNLNKSQYIASAVAVPRYNKDHKVQNLLAYVVLK 456 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 + E+ E+A +A+ + +D + Y +P++ LP GK++ Sbjct: 457 DGVEEQFERALD---ITKAIKADLQDVMMDYMMPSKFLYRKDLPLTPNGKID 505
>ACSL1_MOUSE (P41216) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (LACS 1) Length = 699 Score = 46.6 bits (109), Expect = 8e-05 Identities = 31/103 (30%), Positives = 49/103 (47%) Frame = -1 Query: 625 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKV 446 G GE+C+K ++FK Y K P TAE+ G+ TGD +G I+ R Sbjct: 505 GEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLA 564 Query: 445 GGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 G ++ +IE + L + V + V G E+ + A++VP Sbjct: 565 QGEYIAPEKIENIYLRSEAVAQVFVHG---ESLQAFLIAVVVP 604
>ACSL5_HUMAN (Q9ULC5) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 46.2 bits (108), Expect = 1e-04 Identities = 34/121 (28%), Positives = 54/121 (44%) Frame = -1 Query: 670 VEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDG 491 V+ + + D T + GE+CIK ++FK Y K PE T E+ G+ TGD +G Sbjct: 474 VKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNG 533 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKE 311 I+ R G ++ +IE + VL+ V G E+ + ++VP Sbjct: 534 TLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHG---ESLRSSLVGVVVPDT 590 Query: 310 D 308 D Sbjct: 591 D 591
>LYS2_ASHGO (Q75BB3) L-aminoadipate-semialdehyde dehydrogenase large subunit (EC| 1.2.1.31) (Alpha-aminoadipate reductase) (Alpha-AR) Length = 1385 Score = 45.8 bits (107), Expect = 1e-04 Identities = 44/199 (22%), Positives = 80/199 (40%), Gaps = 44/199 (22%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----------------------------F 527 VGE+ +++ L + Y PE+ E FID F + Sbjct: 619 VGEIYVRAGGLSEGYRGLPEINKEKFIDNWFVDAGHWGGLDLSGDEPWRNYWLGVRDRLY 678 Query: 526 KTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAY 347 +TGD +G GR + D +K+ G+++ EI+ + ++ E L D+ Sbjct: 679 RTGDLGRYLPNGDCECCGRAD-DQVKIRGFRIELGEIDTNISQYPLCRENITLLRKDQNG 737 Query: 346 GEVICAIIVPKEDARERAE--QASKPALTLEALTS--------------WSKDKLAPYKI 215 + + +VP+ D + A A ++ E++ + K +LA Y I Sbjct: 738 ESTLISYLVPRSDQKALASFISAVPESIATESIAGSLIKYHKLINDIRGFLKKRLAGYAI 797 Query: 214 PTRLHLWDSLPRNAMGKVN 158 PT + + + LP N GK++ Sbjct: 798 PTLIMVMERLPLNPNGKID 816
>PCL_ECTHA (P42516) 4-coumarate--CoA ligase (EC 6.2.1.12) (4CL)| (4-coumaroyl-CoA synthase) (Fragment) Length = 391 Score = 45.8 bits (107), Expect = 1e-04 Identities = 32/100 (32%), Positives = 46/100 (46%) Frame = -1 Query: 460 DIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQAS 281 DI+++GG +S + L H+ V CAV E + A IVP A + Sbjct: 299 DIIQIGGVNVSPGHVARRLESHEAVAACAVRS-HGEGSRRRLKAFIVP-------ARSDA 350 Query: 280 KPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 P + L +W + L + PT L + LPRNAMGK+ Sbjct: 351 DPETLRQTLENWIWEHLPAVERPTDLRIGTELPRNAMGKL 390
>FAD28_MYCBO (Q02278) Putative fatty-acid--CoA ligase fadD28 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 580 Score = 45.8 bits (107), Expect = 1e-04 Identities = 42/138 (30%), Positives = 67/138 (48%), Gaps = 14/138 (10%) Frame = -1 Query: 682 LXPRVEAKIIMDDGT--ETKDG-VGELCIKSPSLFKEYWKRPEVTAESF----------- 545 + PR I+D T E DG VGE+ + ++ YW++P+ + +F Sbjct: 377 MLPRSPIVRIVDSDTCIECPDGTVGEIWVHGDNVANGYWQKPDESERTFGGKIVTPSPGT 436 Query: 544 IDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG 365 +G + +TGD+ V DG I+GR D++ V G S +IEA + E T CA + Sbjct: 437 PEGPWLRTGDSGFV-TDGKMFIIGRIK-DLLIVYGRNHSPDDIEATIQE-ITRGRCAAIS 493 Query: 364 LPDEAYGEVICAIIVPKE 311 +P + E + AII K+ Sbjct: 494 VPGDRSTEKLVAIIELKK 511
>ACVS_EMENI (P27742) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3770 Score = 45.8 bits (107), Expect = 1e-04 Identities = 47/172 (27%), Positives = 73/172 (42%), Gaps = 17/172 (9%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTV--TVDEDG 491 VGEL + + + Y RPEVTAE F+ F ++TGD V +G Sbjct: 1753 VGELYLGGEGVARGYHNRPEVTAERFLRNPFQTDSERQNGRNSRLYRTGDLVRWIPGSNG 1812 Query: 490 YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP-DEAYGEVICAIIVPK 314 LGR + + K+ G ++ EIEAV+ H + + V+ E + + V Sbjct: 1813 EIEYLGRNDFQV-KIRGLRIELGEIEAVMSSHPDIKQSVVIAKSGKEGDQKFLVGYFV-- 1869 Query: 313 EDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 AS P L+ A+ + + +L Y IP+ SLP GK++ Sbjct: 1870 ---------ASSP-LSPGAIRRFMQSRLPGYMIPSSFIPISSLPVTPSGKLD 1911 Score = 42.4 bits (98), Expect = 0.001 Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 21/178 (11%) Frame = -1 Query: 628 DGVGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDG 491 + VGEL + + + Y +P +T + FI F ++TGD D Sbjct: 2829 NAVGELYLAGDCVARGYLNQPVLTGDRFIQNPFQTEQDIACGSYPRLYRTGDLFRCRLDR 2888 Query: 490 ----YFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD--EAYGEVICA 329 Y LGR + + K+ GY++ E++ VL V ECAV+ + +AY + Sbjct: 2889 QHQPYLEYLGRADLQV-KIRGYRIEPSEVQNVLASCPGVRECAVVAKYENTDAYSRIAKF 2947 Query: 328 IIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRL-HLWDSLPRNAMGKVN 158 ++ E +S + + K KL Y +P L L LP GK++ Sbjct: 2948 LVGYYTPDTETVSDSS--------ILAHMKSKLPAYMVPKYLCRLEGGLPVTINGKLD 2997 Score = 42.0 bits (97), Expect = 0.002 Identities = 49/188 (26%), Positives = 73/188 (38%), Gaps = 17/188 (9%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFI 482 GEL I + K Y RP++T + FI F +KTGD +G Sbjct: 667 GELHIGGLGISKGYLNRPDLTPQRFIPNPFQTDHEKELGLNQLMYKTGDLARWLPNGEIE 726 Query: 481 ILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDAR 302 LGR + I K+ G ++ EIE+ L + V V+ +GE KE Sbjct: 727 YLGRADFQI-KLRGIRIEPGEIESTLAGYPGVRTSLVVS-KRLRHGE--------KETTN 776 Query: 301 ERA---EQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVNXXXXXXXXE 131 E +++ AL + + KL Y IPTRL +P GK + Sbjct: 777 EHLVGYYVGDNTSVSETALLQFLELKLPRYMIPTRLVRVSQIPVTVNGKADLRALPSVDL 836 Query: 130 V*PRLH*C 107 + P++ C Sbjct: 837 IQPKVSSC 844
>ACSL6_RAT (P33124) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) (Long-chain-fatty-acid--CoA ligase, brain isozyme) Length = 697 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/106 (28%), Positives = 50/106 (47%) Frame = -1 Query: 634 TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADI 455 T G GE+C+K P++FK Y K + T E+ G+ TGD +G I+ R Sbjct: 501 TSKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIF 560 Query: 454 MKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 G ++ +IE + + + V + V G +A+ + I+VP Sbjct: 561 KLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAF---LVGIVVP 603
>HMWP2_YEREN (P48633) High-molecular-weight protein 2 (HMWP2)| Length = 2035 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/123 (27%), Positives = 63/123 (51%), Gaps = 4/123 (3%) Frame = -1 Query: 661 KIIMDDGTETKDGV-GELCIKSPSLFKEYWKRPEVTAESFI---DGGFFKTGDTVTVDED 494 +++ + G + D V GEL I + + Y+ + + F+ D +++TGD D Sbjct: 891 RVVDERGRDCPDWVSGELWIGGIGVAEGYFNDSLRSEQQFLTLPDERWYRTGDLGCYWPD 950 Query: 493 GYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPK 314 G LGR + + KVGGY++ EIE+ L + V + VL + ++ + + A +VP+ Sbjct: 951 GTIEFLGRRDKQV-KVGGYRIELGEIESALSQLAGVKQATVLAIGEKE--KTLAAYVVPQ 1007 Query: 313 EDA 305 +A Sbjct: 1008 SEA 1010
>AAS_ERWCT (Q6D107) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 738 Score = 44.3 bits (103), Expect = 4e-04 Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 10/144 (6%) Frame = -1 Query: 700 KVQSVNLX-PRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------TAE 551 K+ SV L P +E+++I G G L ++ P++ K Y + P V AE Sbjct: 529 KIHSVGLLLPEMESRLITVPGITRG---GRLQLRGPNIMKGYLRVENPGVLETPAAENAE 585 Query: 550 SFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAV 371 + G++ TGD V +DE G+ I+GR K+ G +S +E + ++ + A Sbjct: 586 GELQQGWYDTGDIVELDERGFCTIIGRVKR-FAKLAGEMVSLESVEQLAVKVSPEAQHAA 644 Query: 370 LGLPDEAYGEVICAIIVPKEDARE 299 D + GE + + R+ Sbjct: 645 SAKSDSSKGEALVLFTTDSQITRD 668
>ACSL6_MOUSE (Q91WC3) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 43.9 bits (102), Expect = 5e-04 Identities = 30/106 (28%), Positives = 50/106 (47%) Frame = -1 Query: 634 TKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADI 455 T G GE+C+K P++FK Y K + T E+ G+ TGD +G I+ R Sbjct: 501 TCKGEGEICVKGPNVFKGYLKDEDRTKEALDSDGWLHTGDIGKWLPEGTLKIIDRKKHIF 560 Query: 454 MKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 G ++ +IE + + + V + V G +A+ + I+VP Sbjct: 561 KLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAF---LVGIVVP 603
>ENTF_SHIFL (P29698) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1281 Score = 43.5 bits (101), Expect = 7e-04 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 G+L + L + Y RP++TA FI F ++TGD ++G LGR++ D Sbjct: 804 GDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRSD-D 862 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARE----RAE 290 +K+ G ++ EI+ V+ V + + VI DAR+ Sbjct: 863 QLKIRGQRIELGEIDRVMQALPDVKQAV-------THACVINQAAATGGDARQLVGYLVS 915 Query: 289 QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 Q+ P L AL + ++ L P+ +P L LP +A GK++ Sbjct: 916 QSGLP-LDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLD 958
>LCF1_YEAST (P30624) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 700 Score = 43.5 bits (101), Expect = 7e-04 Identities = 24/91 (26%), Positives = 46/91 (50%) Frame = -1 Query: 643 GTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 464 G K+ GE+ I ++ EY+K E T+++ G+FKTGD + +G+ I+ R Sbjct: 496 GYFAKNNQGEVWITGANVTPEYYKNEEETSQALTSDGWFKTGDIGEWEANGHLKIIDRKK 555 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAV 371 + + G ++ ++E+V ++ V V Sbjct: 556 NLVKTMNGEYIALEKLESVYRSNEYVANICV 586
>ACSL5_MOUSE (Q8JZR0) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 43.5 bits (101), Expect = 7e-04 Identities = 32/105 (30%), Positives = 47/105 (44%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CIK ++FK Y K PE T E G+ TGD +G I+ R G Sbjct: 491 GEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKIVDRKKNIFKLAQG 550 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDA 305 ++ +IE V VL+ V G E+ + ++VP D+ Sbjct: 551 EYIAPEKIENVYSRSRPVLQVFVHG---ESLRSFLIGVVVPDPDS 592
>ACSL6_HUMAN (Q9UKU0) Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 6) (LACS 6) Length = 697 Score = 43.1 bits (100), Expect = 9e-04 Identities = 29/103 (28%), Positives = 48/103 (46%) Frame = -1 Query: 625 GVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKV 446 G GE+C++ P++FK Y K P+ T E+ G+ TGD G I+ R Sbjct: 504 GEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLA 563 Query: 445 GGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 G ++ +IE + + V + V G +A+ + I+VP Sbjct: 564 QGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAF---LVGIVVP 603
>MENE_HAEIN (P44565) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 452 Score = 43.1 bits (100), Expect = 9e-04 Identities = 37/135 (27%), Positives = 70/135 (51%) Frame = -1 Query: 616 ELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGGY 437 E+ +K L YWK ++ + + G+ +T D + ++G +I+GR + ++ GG Sbjct: 298 EIWLKGAGLAMGYWKDRQIVPLTN-NQGWIQTKDK-GIWQEGELVIIGRLD-NMFISGGE 354 Query: 436 KLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQASKPALTLEA 257 + EIE V+++H +V + VL ++ +G+ A++ + E SK A +E Sbjct: 355 NIQPEEIEQVIIQHSSVNQVFVLPQKNKEFGQRPVALV-------DFNEPFSKSA--VEN 405 Query: 256 LTSWSKDKLAPYKIP 212 L + +DKLA +K P Sbjct: 406 LMFFLQDKLARFKQP 420
>ENTF_ECOLI (P11454) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 43.1 bits (100), Expect = 9e-04 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 G+L + L + Y RP++TA FI F ++TGD ++G LGR++ D Sbjct: 800 GDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRSD-D 858 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARE----RAE 290 +K+ G ++ EI+ V+ V + + VI DAR+ Sbjct: 859 QLKIRGQRIELGEIDRVMQALPDVEQAV-------THACVINQAAATGGDARQLVGYLVS 911 Query: 289 QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 Q+ P L AL + ++ L P+ +P L LP +A GK++ Sbjct: 912 QSGLP-LDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLD 954
>ACVS_STRCL (Q01757) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) (Fragment) Length = 805 Score = 42.7 bits (99), Expect = 0.001 Identities = 41/171 (23%), Positives = 71/171 (41%), Gaps = 16/171 (9%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYF 485 +GEL I + Y R ++TAE F+ + ++TGD + G Sbjct: 612 IGELYIGGCGVAPGYLNRDDLTAERFLTNPYASEQDRARGTNARIYRTGDLARMLPSGEV 671 Query: 484 IILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDA 305 +GR++ + K+ G ++ EIEA E+ V +C V+ G D Sbjct: 672 EFMGRSDFQL-KLNGVRVEPGEIEAQATEYAGVRKCVVIAREGAGGGS----------DR 720 Query: 304 RERAEQASKPA--LTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 ++P +T L S+ + +L +P R+ +S+P N GKV+ Sbjct: 721 HLVGYYLTEPGAGVTEAELLSFLERRLIRIMVPARMVRLESIPVNVNGKVD 771
>MENE_SALTY (P37418) 2-succinylbenzoate--CoA ligase (EC 6.2.1.26) (OSB-CoA| synthetase) (o-succinylbenzoyl-CoA synthetase) Length = 455 Score = 42.4 bits (98), Expect = 0.001 Identities = 40/154 (25%), Positives = 71/154 (46%) Frame = -1 Query: 643 GTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTN 464 G E + E+ +++ S+ + YW+ ++ D G+F T D ++ G I GR + Sbjct: 295 GREIRIVDNEVWLRAASMAEGYWRDGKLIP-LVNDEGWFATRDRGELNH-GRLTIAGRLD 352 Query: 463 ADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARERAEQA 284 ++ GG + E+E V+ H V + V+ + D+ +G A++ E A QA Sbjct: 353 -NLFFSGGEGIQPEEVERVINAHPLVQQAFVVPVEDKEFGHRPVAVV-------EYASQA 404 Query: 283 SKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLP 182 L W +DKLA ++ P R W ++P Sbjct: 405 GDVNLA-----EWVRDKLARFQQPVR---WLTMP 430
>ACVS_CEPAC (P25464) N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase| (EC 6.3.2.26) (Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase) (ACV synthetase) (ACVS) Length = 3712 Score = 42.4 bits (98), Expect = 0.001 Identities = 46/187 (24%), Positives = 77/187 (41%), Gaps = 20/187 (10%) Frame = -1 Query: 658 IIMDDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FK 524 ++ DD G VGEL + + + Y RP++TA+ F F +K Sbjct: 1688 VLNDDMKRVPIGAVGELYLGGDGVARGYHNRPDLTADRFPANPFQTEQERLEGRNARLYK 1747 Query: 523 TGDTV----TVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPD 356 TGD V + DG LGR + + K+ G ++ EIEAVL + + + VL Sbjct: 1748 TGDLVRWIHNANGDGEIEYLGRNDFQV-KIRGQRIELGEIEAVLSSYPGIKQSVVLAKDR 1806 Query: 355 EAYGE-VICAIIVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPR 179 + G+ + V +S +L+ +A+ + L Y +P +L P Sbjct: 1807 KNDGQKYLVGYFV-----------SSAGSLSAQAIRRFMLTSLPDYMVPAQLVPIAKFPV 1855 Query: 178 NAMGKVN 158 GK++ Sbjct: 1856 TVSGKLD 1862 Score = 37.0 bits (84), Expect = 0.062 Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 25/179 (13%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF--------------FKTGDTVTVDEDGYFI 482 GEL I + + Y R E+T + F+ + +KTGD G Sbjct: 610 GELHIGGLGISRGYMNREELTRQKFLPNPYQTDKERQRGVNSTMYKTGDLARWLPSGEVE 669 Query: 481 ILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLG----------LPDEAYGEVIC 332 LGR + I K+ G ++ EIE+ L + + V+ + D G +C Sbjct: 670 YLGRADFQI-KLRGIRIEPGEIESTLAMYPGIRASIVVSKKLLSQGQETIQDHLVGYYVC 728 Query: 331 AI-IVPKEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 +P+ D L S+ + KL Y +PTRL +P N GK + Sbjct: 729 DEGHIPEGD-----------------LLSFLEKKLPRYMVPTRLVQLAQIPTNINGKAD 770
>LYS2_CANAL (Q12572) L-aminoadipate-semialdehyde dehydrogenase large subunit (EC| 1.2.1.31) (Alpha-aminoadipate reductase) (Alpha-AR) Length = 1391 Score = 42.4 bits (98), Expect = 0.001 Identities = 45/204 (22%), Positives = 80/204 (39%), Gaps = 49/204 (24%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESFIDGGF----------------------------- 530 VGE+ +++ L + Y P++ A FI + Sbjct: 614 VGEIYVRAAGLAEGYRGLPDLNAAKFITNWYVNPDKWIEQDEANKKSSETSERTWSVKPR 673 Query: 529 ---FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 359 +++GD DG GR + D +K+ G+++ EI+ L +H V E L Sbjct: 674 DRMYRSGDLGRYFSDGNVECCGRAD-DQVKIRGFRIELGEIDTHLSQHPLVRENVTLVRR 732 Query: 358 DEAYGEVICAIIVPKEDARERA---------EQASKPALT--------LEALTSWSKDKL 230 D+ + + IVPK+ + ++++ P + ++ + + K KL Sbjct: 733 DKNEEPTLISYIVPKDSPELKTFFADVDFPLKKSNDPIVKGLVAYRELIKDIKGYLKKKL 792 Query: 229 APYKIPTRLHLWDSLPRNAMGKVN 158 A Y IPT + LP N GKV+ Sbjct: 793 ASYAIPTIIVPLVKLPLNPNGKVD 816
>ACSL5_RAT (O88813) Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 5) (LACS 5) Length = 683 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/105 (28%), Positives = 47/105 (44%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDEDGYFIILGRTNADIMKVGG 440 GE+CIK ++FK Y K PE T E G+ TGD +G I+ R G Sbjct: 491 GEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQG 550 Query: 439 YKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDA 305 ++ +IE V +L+ V G E+ + ++VP ++ Sbjct: 551 EYIAPEKIENVYSRSRPILQVFVHG---ESLRSFLIGVVVPDPES 592
>LCF1_SCHPO (O60135) Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3)| (Long-chain acyl-CoA synthetase 1) (Fatty acid activator 1) Length = 676 Score = 42.0 bits (97), Expect = 0.002 Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 4/129 (3%) Frame = -1 Query: 685 NLXPRVEAKII-MDDGTETKDGV---GELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTG 518 +L P E K++ ++G G GE+ ++ PSL + Y R + ESF G+F+TG Sbjct: 458 SLLPCTEMKLVDCEEGNYNSHGHPPRGEIWLRGPSLTRGYLNRDKENKESFTPDGWFRTG 517 Query: 517 DTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEV 338 D + +G I+ R + G ++ ++E+ V V D+ + Sbjct: 518 DVGELTPEGLLRIIDRKKNLVKTQNGEYIALEKLESRYRTSSLVSNICVYA--DQTKVKP 575 Query: 337 ICAIIVPKE 311 + AIIVP E Sbjct: 576 L-AIIVPNE 583
>VRAA_STAHJ (Q4L3Q0) Putative long chain fatty acid CoA ligase vraA (EC| 6.2.1.-) (Acyl-CoA synthetase) Length = 461 Score = 42.0 bits (97), Expect = 0.002 Identities = 40/172 (23%), Positives = 72/172 (41%) Frame = -1 Query: 676 PRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWKRPEVTAESFIDGGFFKTGDTVTVDE 497 P V K+ D + +G L ++S ++ Y V S+I+ TGD + Sbjct: 297 PNVSIKLEAQDNRK----IGLLKVQSNMIYSGYVDVGVVQPHSWIE-----TGDYAYIQN 347 Query: 496 DGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVP 317 + +++ ++ D + +GG + IE + D + E V+G P +GE+ I V Sbjct: 348 NQLYLVSRKS--DRLIIGGKNIYPNVIEQQVKSLDGIEEAVVVGEPHRRFGEIAVLIYVG 405 Query: 316 KEDARERAEQASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKV 161 ++ L L + + L+ Y+IP++L LP GKV Sbjct: 406 NQE------------LDYTTLRRYLRQTLSRYEIPSKLVRVKDLPFTNSGKV 445
>ENTF_ECO57 (Q8XBV9) Enterobactin synthetase component F (EC 2.7.7.-)| (Enterochelin synthase F) (Serine-activating enzyme) (Seryl-AMP ligase) Length = 1293 Score = 41.6 bits (96), Expect = 0.003 Identities = 44/164 (26%), Positives = 72/164 (43%), Gaps = 10/164 (6%) Frame = -1 Query: 619 GELCIKSPSLFKEYWKRPEVTAESFIDGGF------FKTGDTVTVDEDGYFIILGRTNAD 458 G+L + L + Y RP++TA FI F ++TGD ++G LGR++ D Sbjct: 800 GDLYLTGIQLAQGYLGRPDLTASRFIADPFVPGERMYRTGDVARWLDNGAVEYLGRSD-D 858 Query: 457 IMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARE----RAE 290 +K+ G ++ EI+ V+ V + + VI DAR+ Sbjct: 859 QLKIRGQRIELGEIDRVMQALPDVEQAV-------THACVINQAAATGGDARQLVGYLVS 911 Query: 289 QASKPALTLEALTSWSKDKLAPYKIPTRLHLWDSLPRNAMGKVN 158 Q+ P L AL + ++ L P+ P L LP +A GK++ Sbjct: 912 QSGLP-LDTSALQAQLRETLPPHMAPVVLLQLPQLPLSANGKLD 954
>S27A3_MOUSE (O88561) Long-chain fatty acid transport protein 3 (EC 6.2.1.-)| (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3) Length = 667 Score = 40.0 bits (92), Expect = 0.007 Identities = 37/119 (31%), Positives = 51/119 (42%), Gaps = 3/119 (2%) Frame = -1 Query: 532 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDE 353 FF TGD + DE G+ RT D ++ G ++ E+ VL D + E + G Sbjct: 507 FFNTGDLLVCDEQGFLHFHDRT-GDTIRWKGENVATTEVAEVLETLDFLQEVNIYG---- 561 Query: 352 AYGEVICAIIVPKEDARE-RAEQASKP--ALTLEALTSWSKDKLAPYKIPTRLHLWDSL 185 + VP + R A A +P AL L L S + L PY P L L +SL Sbjct: 562 --------VTVPGHEGRAGMAALALRPPQALNLVQLYSHVSENLPPYARPRFLRLQESL 612
>AAS_SALTI (Q8Z406) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 39.7 bits (91), Expect = 0.010 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 9/144 (6%) Frame = -1 Query: 682 LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------TAESFIDGGF 530 + P ++A+++ G E G L +K P++ Y + +P V A + G+ Sbjct: 536 ILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGW 592 Query: 529 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 350 + TGD V DE+G+ I GR K+ G +S +E + L A D + Sbjct: 593 YDTGDIVRFDENGFVQIQGRAKR-FAKIAGEMVSLEMVEQLALGVSAEKMHATAIKSDAS 651 Query: 349 YGEVICAIIVPKEDARERAEQASK 278 GE + E RE+ + ++ Sbjct: 652 KGEALVLFTTDSELTREKLQHYAR 675
>S27A5_MOUSE (Q4LDG0) Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid| CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) Length = 689 Score = 39.3 bits (90), Expect = 0.012 Identities = 21/58 (36%), Positives = 32/58 (55%) Frame = -1 Query: 532 FFKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLP 359 +F TGD +T+D++G+F R D + G +S E+E VL D + E V G+P Sbjct: 529 YFNTGDVLTLDQEGFFYFQDRL-GDTFRWKGENVSTGEVECVLSSLDFLEEVNVYGVP 585
>AAS_SALPA (Q5PEN7) AAS bifunctional protein [Includes:| 2-acylglycerophosphoethanolamine acyltransferase (EC 2.3.1.40) (Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase) (2-acyl-GPE acyltransferase); Acyl-[acyl-carrier-protein] synthetase (EC 6 Length = 719 Score = 39.3 bits (90), Expect = 0.012 Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 9/144 (6%) Frame = -1 Query: 682 LXPRVEAKIIMDDGTETKDGVGELCIKSPSLFKEYWK--RPEV-------TAESFIDGGF 530 + P ++A+++ G E G L +K P++ Y + +P V A + G+ Sbjct: 536 ILPGMDARLLAVPGIENG---GRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGW 592 Query: 529 FKTGDTVTVDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEA 350 + TGD V DE+G+ I GR K+ G +S +E + L A D + Sbjct: 593 YDTGDIVRFDENGFVQIQGRAKR-FAKIAGEMVSLEMVEQLALGVSADKMHATAIKSDAS 651 Query: 349 YGEVICAIIVPKEDARERAEQASK 278 GE + E RE+ + ++ Sbjct: 652 KGEALVLFTTDSELTREKLQHYAR 675
>FAD26_MYCTU (Q10976) Putative fatty-acid--CoA ligase fadD26 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 39.3 bits (90), Expect = 0.012 Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 11/134 (8%) Frame = -1 Query: 622 VGELCIKSPSLFKEYWKRPEVTAESF-----------IDGGFFKTGDTVTVDEDGYFIIL 476 VGE+ + + YW++P+ TA+ F +G + +TGD + V DG I+ Sbjct: 402 VGEIWVHGDHVTMGYWQKPKQTAQVFDAKLVDPAPAAPEGPWLRTGD-LGVISDGELFIM 460 Query: 475 GRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAIIVPKEDARER 296 GR D++ V G +IEA + E T A + +PD+ +++ I + + R Sbjct: 461 GRIK-DLLIVDGRNHYPDDIEATIQE-ITGGRAAAIAVPDDITEQLVAII-----EFKRR 513 Query: 295 AEQASKPALTLEAL 254 A + L L ++ Sbjct: 514 GSTAEEVMLKLRSV 527
>FAD25_MYCTU (Q50586) Putative fatty-acid--CoA ligase fadD25 (EC 6.2.1.-)| (Acyl-CoA synthetase) Length = 583 Score = 39.3 bits (90), Expect = 0.012 Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 12/126 (9%) Frame = -1 Query: 649 DDGTETKDG-VGELCIKSPSLFKEYWKRPEVTAESFI-----------DGGFFKTGDTVT 506 D G E G +GE+ + ++ YW++PE T +F G + +TGD+ Sbjct: 394 DTGIERPAGTIGEIWVHGDNVAIGYWQKPEATERTFSATIVNPSEGTPAGPWLRTGDSGF 453 Query: 505 VDEDGYFIILGRTNADIMKVGGYKLSALEIEAVLLEHDTVLECAVLGLPDEAYGEVICAI 326 + E G I+GR D++ V G S +IEA ++ + CA + + + +++ I Sbjct: 454 LSE-GELFIMGRIK-DLLIVYGRNHSPDDIEAT-IQTISPGRCAAIAVSEHGAEKLVAII 510 Query: 325 IVPKED 308 + K+D Sbjct: 511 ELKKKD 516 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 101,530,039 Number of Sequences: 219361 Number of extensions: 2102883 Number of successful extensions: 5782 Number of sequences better than 10.0: 278 Number of HSP's better than 10.0 without gapping: 5177 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5405 length of database: 80,573,946 effective HSP length: 109 effective length of database: 56,663,597 effective search space used: 7479594804 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
