ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
menu 
| Clone Name | rbaal3a14 |
|---|---|
| Clone Library Name | barley_pub |
>M3K12_MOUSE (Q60700) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 100 bits (249), Expect = 4e-21 Identities = 49/103 (47%), Positives = 68/103 (66%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ VSEKVD++SFG+ LWE+LTGE PY ++ AII G+ +NSL PVP Sbjct: 309 WMAPEVIRNEP--VSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 366 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 +C ++IL+ QCW++ P RPSF ++ L SA + S Q Sbjct: 367 SCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQ 409
>M3K12_HUMAN (Q12852) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 859 Score = 100 bits (249), Expect = 4e-21 Identities = 49/103 (47%), Positives = 68/103 (66%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ VSEKVD++SFG+ LWE+LTGE PY ++ AII G+ +NSL PVP Sbjct: 276 WMAPEVIRNEP--VSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 333 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 +C ++IL+ QCW++ P RPSF ++ L SA + S Q Sbjct: 334 SCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQ 376
>M3K12_RAT (Q63796) Mitogen-activated protein kinase kinase kinase 12 (EC| 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK) Length = 888 Score = 99.8 bits (247), Expect = 6e-21 Identities = 49/103 (47%), Positives = 67/103 (65%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ VSEKVD++SFG+ LWE+LTGE PY ++ AII G+ +NSL PVP Sbjct: 309 WMAPEVIRNEP--VSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 366 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 +C ++IL+ QCW+ P RPSF ++ L SA + S Q Sbjct: 367 SCPDGFKILLRQCWNRKPRNRPSFRQILLHLDIASADVLSTPQ 409
>M3K13_HUMAN (O43283) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase) Length = 966 Score = 97.8 bits (242), Expect = 2e-20 Identities = 48/96 (50%), Positives = 63/96 (65%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ VSEKVD++SFG+ LWE+LTGE PY ++ AII G+ +NSL PVP Sbjct: 319 WMAPEVIRNEP--VSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 376 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSA 361 TC ++ILM+Q W + P RPSF + L SA Sbjct: 377 TCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASA 412
>M3K13_PONPY (Q5R8X7) Mitogen-activated protein kinase kinase kinase 13 (EC| 2.7.11.25) Length = 966 Score = 96.7 bits (239), Expect = 5e-20 Identities = 47/96 (48%), Positives = 63/96 (65%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 W+APE++ VSEKVD++SFG+ LWE+LTGE PY ++ AII G+ +NSL PVP Sbjct: 319 WLAPEVIRNEP--VSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPS 376 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSA 361 TC ++ILM+Q W + P RPSF + L SA Sbjct: 377 TCPDGFKILMKQTWQSKPRNRPSFRQTLMHLDIASA 412
>KYK2_DICDI (P18161) Tyrosine-protein kinase 2 (EC 2.7.10.2) (Fragment)| Length = 410 Score = 92.4 bits (228), Expect = 1e-18 Identities = 41/95 (43%), Positives = 61/95 (64%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 W PEL + SEKVDV+ F + +WEILTGE P++++ + LRPP+PE Sbjct: 275 WRPPELTK-NLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQRSAQVAYAGLRPPIPE 333 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMS 364 CDPE ++L+ QCW A+P+ RP FT + ++L+ +S Sbjct: 334 YCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEIS 368
>M3K11_HUMAN (Q16584) Mitogen-activated protein kinase kinase kinase 11 (EC| 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase) Length = 847 Score = 90.1 bits (222), Expect = 5e-18 Identities = 41/98 (41%), Positives = 59/98 (60%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ S+ S+ DV+SFG+ LWE+LTGE PY + C A+ G+ N L P+P Sbjct: 288 WMAPEVIKAST--FSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPS 345 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 TC + LM CW+ +P RP F + +L A+ A + Sbjct: 346 TCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQV 383
>M3KL4_HUMAN (Q5TCX8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase 4) Length = 1036 Score = 87.4 bits (215), Expect = 3e-17 Identities = 40/102 (39%), Positives = 63/102 (61%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ SS S+ D++S+G+ LWE+LTGE PY + A+ G+ N L P+P Sbjct: 310 WMAPEVIK--SSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTLPIPS 367 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRV 343 TC + LM++CW +P IRPSF + ++L A+ + + + Sbjct: 368 TCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIEGAVMTEM 409
>M3K9_HUMAN (P80192) Mitogen-activated protein kinase kinase kinase 9 (EC| 2.7.11.25) (Mixed lineage kinase 1) Length = 1104 Score = 87.0 bits (214), Expect = 4e-17 Identities = 40/91 (43%), Positives = 58/91 (63%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ +S S+ DV+S+G+ LWE+LTGE P+ + A+ G+ N L P+P Sbjct: 315 WMAPEVIR--ASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPS 372 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 TC + LME CW+ +P RPSFT + D+L Sbjct: 373 TCPEPFAKLMEDCWNPDPHSRPSFTNILDQL 403
>M3K10_HUMAN (Q02779) Mitogen-activated protein kinase kinase kinase 10 (EC| 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST) Length = 954 Score = 84.7 bits (208), Expect = 2e-16 Identities = 42/106 (39%), Positives = 62/106 (58%), Gaps = 2/106 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ S S+ DV+SFG+ LWE+LTGE PY + A+ G+ N L P+P Sbjct: 269 WMAPEVIR--LSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPS 326 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM--SAMLQSRVQA 337 TC + L+E+CW +P RP F + RL + SA+ Q +++ Sbjct: 327 TCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLES 372
>M3KSL_DROME (Q95UN8) Mitogen-activated protein kinase kinase kinase (EC| 2.7.11.25) (Mixed lineage kinase) (dMLK) (Protein slipper) Length = 1161 Score = 84.0 bits (206), Expect = 4e-16 Identities = 37/95 (38%), Positives = 58/95 (61%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WM PE++ S S S+ DV+S+G+ LWE++TGE PY ++ G+ N+L P+P+ Sbjct: 311 WMPPEVI--SVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPK 368 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMS 364 TC W LM+ CW +P RP F E+ +L +++ Sbjct: 369 TCPETWGALMKSCWQTDPHKRPGFKEILKQLESIA 403
>KYK1_DICDI (P18160) Non-receptor tyrosine kinase spore lysis A (EC 2.7.10.2)| (Tyrosine-protein kinase 1) Length = 1584 Score = 82.0 bits (201), Expect = 1e-15 Identities = 38/94 (40%), Positives = 59/94 (62%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 +MAPE+ G S+ SEK DV+S+G+ L+E+LT +EP +M + S RPP+P Sbjct: 1471 YMAPEVFKGDSN--SEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPL 1528 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 T +W+ ++ QCW +NPD RP+F ++ L+ M Sbjct: 1529 TTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEM 1562
>YR831_MIMIV (Q7T6Y2) Putative serine/threonine-protein kinase/receptor R831| precursor (EC 2.7.11.1) Length = 1624 Score = 79.7 bits (195), Expect = 7e-15 Identities = 39/95 (41%), Positives = 58/95 (61%), Gaps = 4/95 (4%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 W+APE+LN S+ DV+SFGI LWE+LT E+PY M AI ++ + +RPP+ + Sbjct: 951 WIAPEILNDSTEVDYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISD 1010 Query: 468 TC----DPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E+ L++QCW ++ IRP+F E+ RL Sbjct: 1011 EAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTRL 1045 Score = 79.0 bits (193), Expect = 1e-14 Identities = 38/102 (37%), Positives = 59/102 (57%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 W APE++ G + EK DVFSFG+ +WE+LTG+EP+A + + I+ RP +P Sbjct: 1526 WTAPEVIRGE--KYCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGG-RPIIPS 1582 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRV 343 C E+ L+++CW A RP+ TEV +L ++ +V Sbjct: 1583 DCPHEFAKLIKKCWHAKAHKRPTMTEVVQQLMLITEQFDHKV 1624
>CTR1_ARATH (Q05609) Serine/threonine-protein kinase CTR1 (EC 2.7.11.1)| Length = 821 Score = 75.5 bits (184), Expect = 1e-13 Identities = 37/105 (35%), Positives = 60/105 (57%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE+L S +EK DV+SFG+ LWE+ T ++P+ N++ ++ + R +P Sbjct: 717 WMAPEVLRDEPS--NEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPR 774 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAP 334 +P+ ++E CW+ P RPSF + D LR +++S V P Sbjct: 775 NLNPQVAAIIEGCWTNEPWKRPSFATIMDLLR---PLIKSAVPPP 816
>HT1_ARATH (Q2MHE4) Serine/threonine-protein kinase HT1 (EC 2.7.11.1) (High| leaf temperature protein 1) Length = 390 Score = 74.7 bits (182), Expect = 2e-13 Identities = 34/87 (39%), Positives = 49/87 (56%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ + KVDV+SFGI LWE+ T P+ M + + RPP+P Sbjct: 252 WMAPEMIK--EKPYTRKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPA 309 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEV 388 +C P L+++CWS NP RP F+ + Sbjct: 310 SCQPALAHLIKRCWSENPSKRPDFSNI 336
>RIPK1_HUMAN (Q13546) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 671 Score = 73.9 bits (180), Expect = 4e-13 Identities = 37/95 (38%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPV-- 475 +MAPE LN +++ +EK DV+SF + LW I +EPY N C + + + RP V Sbjct: 192 YMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDD 251 Query: 474 -PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 E C E LM+ CW ANP+ RP+F + ++ R Sbjct: 252 ITEYCPREIISLMKLCWEANPEARPTFPGIEEKFR 286
>RIPK1_MOUSE (Q60855) Receptor-interacting serine/threonine-protein kinase 1 (EC| 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein) Length = 656 Score = 73.6 bits (179), Expect = 5e-13 Identities = 39/95 (41%), Positives = 54/95 (56%), Gaps = 3/95 (3%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 +MAPE LN +++ +EK DV+SFGI LW I +EPY N+ C + + RP V E Sbjct: 193 YMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEE 252 Query: 468 T---CDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 C E LME+CW A P+ RP+F + + R Sbjct: 253 ILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFR 287
>MLTK_MOUSE (Q9ESL4) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) ( Length = 802 Score = 72.0 bits (175), Expect = 1e-12 Identities = 35/95 (36%), Positives = 54/95 (56%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ S VSE D +S+G+ LWE+LT E P+ + + +V + R +P Sbjct: 172 WMAPEVIQ--SLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPS 229 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMS 364 +C + L+ QCW A+ RPSF ++ L +MS Sbjct: 230 SCPRSFAELLHQCWEADAKKRPSFKQIISILESMS 264
>MLTK_HUMAN (Q9NYL2) Mitogen-activated protein kinase kinase kinase MLT (EC| 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper-and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase Length = 800 Score = 72.0 bits (175), Expect = 1e-12 Identities = 35/95 (36%), Positives = 54/95 (56%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE++ S VSE D +S+G+ LWE+LT E P+ + + +V + R +P Sbjct: 172 WMAPEVIQ--SLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPS 229 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMS 364 +C + L+ QCW A+ RPSF ++ L +MS Sbjct: 230 SCPRSFAELLHQCWEADAKKRPSFKQIISILESMS 264
>M3K7_HUMAN (O43318) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 606 Score = 71.2 bits (173), Expect = 2e-12 Identities = 38/88 (43%), Positives = 52/88 (59%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAI-IGGIVNNSLRPPVP 472 WMAPE+ GS+ SEK DVFS+GI LWE++T +P+ + A I V+N RPP+ Sbjct: 195 WMAPEVFEGSN--YSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLI 252 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 + LM +CWS +P RPS E+ Sbjct: 253 KNLPKPIESLMTRCWSKDPSQRPSMEEI 280
>M3K7_MOUSE (Q62073) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) Length = 579 Score = 71.2 bits (173), Expect = 2e-12 Identities = 38/88 (43%), Positives = 52/88 (59%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAI-IGGIVNNSLRPPVP 472 WMAPE+ GS+ SEK DVFS+GI LWE++T +P+ + A I V+N RPP+ Sbjct: 195 WMAPEVFEGSN--YSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLI 252 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 + LM +CWS +P RPS E+ Sbjct: 253 KNLPKPIESLMTRCWSKDPSQRPSMEEI 280
>PTK7_CHICK (Q91048) Tyrosine-protein kinase-like 7 precursor (Kinase-like| protein) Length = 1051 Score = 70.9 bits (172), Expect = 3e-12 Identities = 35/92 (38%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM PE + S K DV+SFG+ +WE+ T GE PYA + ++ G+ + + P P Sbjct: 953 WMPPEAV--LEDEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQP 1010 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C LM++CW+ +P RPSF+E+ L Sbjct: 1011 EGCPSRLTKLMQRCWAPSPKDRPSFSELAAAL 1042
>TNI3K_RAT (Q7TQP6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 834 Score = 69.7 bits (169), Expect = 7e-12 Identities = 34/91 (37%), Positives = 54/91 (59%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE+ +R + K DVFS+ + LWE+LTGE P+A++ A + + +RPP+ Sbjct: 629 WMAPEVFT-QCTRYTIKADVFSYSLCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGY 687 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 + L+ + W+A P+ RP F+EV +L Sbjct: 688 SIPKPISSLLIRGWNACPEGRPEFSEVVSKL 718
>ZAP70_HUMAN (P43403) Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa| zeta-associated protein) (Syk-related tyrosine kinase) Length = 619 Score = 69.3 bits (168), Expect = 9e-12 Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 1/106 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + S + DV+S+G+ +WE L+ G++PY M G + + R P Sbjct: 505 WYAPECIN--FRKFSSRSDVWSYGVTMWEALSYGQKPYKKMK-GPEVMAFIEQGKRMECP 561 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAP 334 C PE LM CW + RP F V R+RA L S+V+ P Sbjct: 562 PECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGP 607
>TNI3K_HUMAN (Q59H18) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 936 Score = 69.3 bits (168), Expect = 9e-12 Identities = 35/91 (38%), Positives = 54/91 (59%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE+ +R + K DVFS+ + LWEILTGE P+A++ A + + +RPP+ Sbjct: 731 WMAPEVFT-QCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGY 789 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 + L+ + W+A P+ RP F+EV +L Sbjct: 790 SIPKPISSLLIRGWNACPEGRPEFSEVVMKL 820
>FAK1_RAT (O35346) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1055 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE +N R + DV+ FG+ +WEIL G +P+ + +IG I N R P+P Sbjct: 588 WMAPESIN--FRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE-RLPMP 644 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C P LM +CW+ +P RP FTE+ +L Sbjct: 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 676
>FAK1_MOUSE (P34152) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1090 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE +N R + DV+ FG+ +WEIL G +P+ + +IG I N R P+P Sbjct: 626 WMAPESIN--FRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE-RLPMP 682 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C P LM +CW+ +P RP FTE+ +L Sbjct: 683 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 714
>FAK1_XENLA (Q91738) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1068 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE +N R + DV+ FG+ +WEIL G +P+ + +IG I N R P+P Sbjct: 601 WMAPESIN--FRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIENGE-RLPMP 657 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C P LM +CW+ +P RP FTE+ +L Sbjct: 658 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 689
>FAK1_CHICK (Q00944) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| Length = 1053 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE +N R + DV+ FG+ +WEIL G +P+ + +IG I N R P+P Sbjct: 588 WMAPESIN--FRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE-RLPMP 644 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C P LM +CW+ +P RP FTE+ +L Sbjct: 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 676
>FAK1_HUMAN (Q05397) Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK)| (Protein-tyrosine kinase 2) Length = 1052 Score = 68.2 bits (165), Expect = 2e-11 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE +N R + DV+ FG+ +WEIL G +P+ + +IG I N R P+P Sbjct: 588 WMAPESIN--FRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE-RLPMP 644 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C P LM +CW+ +P RP FTE+ +L Sbjct: 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQL 676
>TNI3K_MOUSE (Q5GIG6) Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1)| (TNNI3-interacting kinase) (Cardiac ankyrin repeat kinase) Length = 833 Score = 67.0 bits (162), Expect = 5e-11 Identities = 33/91 (36%), Positives = 53/91 (58%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE+ +R + K DVFS+ + LWE+L GE P+A++ A + + +RPP+ Sbjct: 628 WMAPEVFT-QCTRYTIKADVFSYALCLWELLIGEIPFAHLKPAAAAADMAYHHIRPPIGY 686 Query: 468 TCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 + L+ + W+A P+ RP F+EV +L Sbjct: 687 SIPKPISSLLMRGWNACPEGRPEFSEVVRKL 717
>FGFR1_DROME (Q07407) Fibroblast growth factor receptor homolog 1 precursor (EC| 2.7.10.1) (Protein heartless) Length = 729 Score = 66.6 bits (161), Expect = 6e-11 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L K DV+S+GI LWEI+T G++PY + + + + R P Sbjct: 599 WMAPESLQ--EKFYDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEKP 656 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 C ILM QCW N D RP FTE+ + M +LQ++ Sbjct: 657 AKCSMNIYILMRQCWHFNADDRPPFTEIVE---YMDKLLQTK 695
>M3K7_DROME (Q9V3Q6) Mitogen-activated protein kinase kinase kinase 7 (EC| 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1) Length = 678 Score = 66.2 bits (160), Expect = 8e-11 Identities = 32/83 (38%), Positives = 46/83 (55%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE+ GS + +EK D+FS+ I LWE+L+ ++P+ + I + RPP+ Sbjct: 179 WMAPEVFEGS--KYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLLT 236 Query: 468 TCDPEWRILMEQCWSANPDIRPS 400 TC LM CW P+ RPS Sbjct: 237 TCPKRIEDLMTACWKTVPEDRPS 259
>PHY1_CERPU (P25848) Light-sensor Protein kinase [Includes: Phytochrome; Protein| kinase (EC 2.7.11.1)] Length = 1307 Score = 65.1 bits (157), Expect = 2e-10 Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 13/113 (11%) Frame = -2 Query: 648 WMAPELLN-------------GSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIG 508 WMAPE++N G + K DV+SFG+ +E+LTG+ P+ + Sbjct: 1179 WMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDVPFPEEKNPNNVK 1238 Query: 507 GIVNNSLRPPVPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQS 349 +V +RP +P C E + L+ CW+ +P RPSF + +L+ + +L + Sbjct: 1239 RMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVICQKLKYLKYLLMT 1291
>RIPK3_RAT (Q9Z2P5) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (Homocysteine respondent protein HCYP2) Length = 478 Score = 65.1 bits (157), Expect = 2e-10 Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 8/112 (7%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPV-- 475 ++APELL+ + + S+ DV+SFG+ +W +L G E I G + N RPP+ Sbjct: 188 YLAPELLD-NDGKASKASDVYSFGVLVWTVLAGREAEVVDKTSLIRGAVCNRQRRPPLTE 246 Query: 474 -----PETCDPE-WRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQA 337 PET E + LM CWS+ P RPSF + + + ++Q +V A Sbjct: 247 LPPDSPETPGLEGLKELMTHCWSSEPKDRPSFQDCESKTNNVYILVQDKVDA 298
>ANKK1_HUMAN (Q8NFD2) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288) Length = 765 Score = 64.7 bits (156), Expect = 2e-10 Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 7/114 (6%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 ++ PE+ S+ K DV+SF I +WE+LT ++PY+ + II + +RP + Sbjct: 190 YIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVA-AGMRPSLQP 248 Query: 468 TCDPEWRI-------LMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPGS 328 D +W LM++CW +P RP F ++T + ++LQSRV P S Sbjct: 249 VSD-QWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPES 301
>FES_HUMAN (P07332) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2)| (C-Fes) Length = 822 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/95 (41%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PY N+ V R P P Sbjct: 726 WTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCP 782 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C LMEQCW+ P RPSF+ + L+++ Sbjct: 783 ELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSI 817
>FES_FSVGA (P00542) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 609 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/95 (41%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PY N+ V R P P Sbjct: 513 WTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCP 569 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C LMEQCW+ P RPSF+ + L+++ Sbjct: 570 ELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSI 604
>FES_FELCA (P14238) Proto-oncogene tyrosine-protein kinase FES/FPS (EC| 2.7.10.2) (C-FES) Length = 820 Score = 64.7 bits (156), Expect = 2e-10 Identities = 39/95 (41%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PY N+ V R P P Sbjct: 724 WTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCP 780 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C LMEQCW+ P RPSF+ + L+++ Sbjct: 781 ELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSI 815
>FES_MOUSE (P16879) Proto-oncogene tyrosine-protein kinase Fes/Fps (EC| 2.7.10.2) (C-Fes) Length = 820 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PY N+ V R P P Sbjct: 724 WTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNL-TNQQTREFVEKGHRLPCP 780 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C LMEQCW+ P RPSF+ + L ++ Sbjct: 781 ELCPDAVFRLMEQCWAYEPGQRPSFSIICQELHSI 815
>INSR_XENLA (Q9PVZ4) Insulin receptor precursor (EC 2.7.10.1) (IR) (Xe-InsR)| (XTK-1b) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1362 Score = 64.3 bits (155), Expect = 3e-10 Identities = 35/94 (37%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Frame = -2 Query: 648 WMAPELL-NGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WM+PE L +G + S DV+SFG+ LWEI + E+PY + ++ +++ Sbjct: 1191 WMSPESLKDGVFTAFS---DVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDH- 1246 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 PE C P LM+ CW NP +RP+F E+ D L+ Sbjct: 1247 PENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLK 1280
>TIE1_BRARE (O73792) Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)| (Fragment) Length = 184 Score = 63.5 bits (153), Expect = 5e-10 Identities = 38/95 (40%), Positives = 50/95 (52%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + K DV+SFG+ LWEI++ G PY M C + + R P Sbjct: 65 WMAIESLNYSV--YTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQG-YRMEQP 121 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 CD E LM QCW P RP F++++ +L M Sbjct: 122 RNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRM 156
>INSRR_HUMAN (P14616) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1297 Score = 63.5 bits (153), Expect = 5e-10 Identities = 33/93 (35%), Positives = 52/93 (55%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L DV+SFG+ LWEI+T E+PY + ++ +++ + + Sbjct: 1158 WMAPESLKDGIFTTHS--DVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL- 1214 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 E C + + LM +CW NP +RPSFT + D ++ Sbjct: 1215 EGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQ 1247
>PTK7_HUMAN (Q13308) Tyrosine-protein kinase-like 7 precursor (Colon carcinoma| kinase 4) (CCK-4) Length = 1070 Score = 63.2 bits (152), Expect = 7e-10 Identities = 33/93 (35%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPE-LLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WM+PE +L G S K DV++ G+ +WE+ T GE P+ ++ + R P Sbjct: 972 WMSPEAILEGD---FSTKSDVWASGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQ 1028 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 PE C + LM++CW+ +P RPSF+E+ L Sbjct: 1029 PEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
>FRK_HUMAN (P42685) Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear| tyrosine protein kinase RAK) Length = 505 Score = 63.2 bits (152), Expect = 7e-10 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + S++ S K DV+SFGI L+EI+T G+ PY+ M +I + N R P P Sbjct: 399 WTAPEAIR--SNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQN-YRLPQP 455 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 C ++ +M +CW+A P RP+F Sbjct: 456 SNCPQQFYNIMLECWNAEPKERPTF 480
>ROS_HUMAN (P08922) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2347 Score = 63.2 bits (152), Expect = 7e-10 Identities = 42/114 (36%), Positives = 61/114 (53%), Gaps = 7/114 (6%) Frame = -2 Query: 648 WMAPE-LLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L++G + S DV+SFGI +WEILT G +PY H + V R Sbjct: 2127 WMAPESLMDGIFTTQS---DVWSFGILIWEILTLGHQPYP-AHSNLDVLNYVQTGGRLEP 2182 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRA-----MSAMLQSRVQAPGS 328 P C + LM QCW+ PD RP+F + ++L+ ++++ Q R +A S Sbjct: 2183 PRNCPDDLWNLMTQCWAQEPDQRPTFHRIQNQLQLFRNFFLNSIYQCRDEANNS 2236
>MATK_RAT (P41243) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase BATK) Length = 467 Score = 63.2 bits (152), Expect = 7e-10 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + R S K DV+SFG+ LWE+ + G PY M + V R P Sbjct: 350 WTAPEALK--NGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEV-SEAVEKGYRMEPP 406 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 ++C LM CW A P RP F ++ ++L Sbjct: 407 DSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKL 438
>FES_FSVST (P00543) Tyrosine-protein kinase transforming protein Fes (EC| 2.7.10.2) Length = 477 Score = 63.2 bits (152), Expect = 7e-10 Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PY N+ V R P P Sbjct: 381 WTAPEALN--YGRYSSESDVWSFGILLWETFSLGASPYPNLS-NQQTREFVEKGGRLPCP 437 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C LMEQCW+ P RPSF+ L+++ Sbjct: 438 ELCPDAVFRLMEQCWAYEPGQRPSFSAFYQELQSI 472
>HCK_MACFA (Q95M30) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 503 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/104 (37%), Positives = 52/104 (50%), Gaps = 1/104 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N SS + K DV+SFGI L EI+T G PY M +I + R P P Sbjct: 400 WTAPEAINFGSSTI--KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL-ERGYRMPRP 456 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 E C E +M +CW P+ RP+F + L +S+ Q Sbjct: 457 ENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQ 500
>SRMS_MOUSE (Q62270) Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70)| Length = 496 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/100 (39%), Positives = 56/100 (56%), Gaps = 2/100 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 W APE N RV S+K DV+SFGI L+E+ T G+ PY M + I + R P Sbjct: 396 WTAPEAAN---YRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQI-SRGYRLPR 451 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 P C E +LM +CW +P+ RP+F + ++L A++ L Sbjct: 452 PAVCPAEVYVLMVECWKGSPEERPTFAILREKLNAINRRL 491
>ZAP70_MOUSE (P43404) Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa| zeta-associated protein) (Syk-related tyrosine kinase) Length = 618 Score = 62.0 bits (149), Expect = 1e-09 Identities = 35/106 (33%), Positives = 50/106 (47%), Gaps = 1/106 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + S + DV+S+G+ +WE + G++PY M G + + R P Sbjct: 504 WYAPECIN--FRKFSSRSDVWSYGVTMWEAFSYGQKPYKKMK-GPQVLDFIKQGKRMECP 560 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAP 334 C PE LM CW + RP F V R+R SR + P Sbjct: 561 PECPPEMYALMSDCWIYKWEDRPDFLTVEQRMRNYYYSPASRAEGP 606
>FAK2_RAT (P70600) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) Length = 1009 Score = 62.0 bits (149), Expect = 1e-09 Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE +N R + DV+ F + +WEIL+ G++P+ + +IG ++ R P P Sbjct: 591 WMSPESIN--FRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIG-VLEKGDRLPKP 647 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 E C P LM +CW +P RP FTE+ Sbjct: 648 ELCPPVLYTLMTRCWDYDPSDRPRFTEL 675
>FAK2_MOUSE (Q9QVP9) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 62.0 bits (149), Expect = 1e-09 Identities = 33/88 (37%), Positives = 50/88 (56%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE +N R + DV+ F + +WEIL+ G++P+ + +IG ++ R P P Sbjct: 591 WMSPESIN--FRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIG-VLEKGDRLPKP 647 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 E C P LM +CW +P RP FTE+ Sbjct: 648 ELCPPVLYTLMTRCWDYDPSDRPRFTEL 675
>TIE1_BOVIN (Q06805) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1136 Score = 62.0 bits (149), Expect = 1e-09 Identities = 38/95 (40%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + K DV+SFG+ LWEI++ G PY M C + + + R P Sbjct: 1017 WMAIESLNYSV--YTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQ-AYRMEQP 1073 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 CD E LM QCW P RP F ++ +L M Sbjct: 1074 RNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1108
>MATK_MOUSE (P41242) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK) Length = 505 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/92 (36%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + R S K DV+SFG+ LWE+ + G PY M + V R P Sbjct: 388 WTAPEALK--NGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEV-SEAVEKGYRMEPP 444 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 + C LM CW A P RP F ++ ++L Sbjct: 445 DGCPGSVHTLMGSCWEAEPARRPPFRKIVEKL 476
>HTK7_HYDAT (Q25197) Putative insulin-like peptide receptor precursor (EC| 2.7.10.1) Length = 1477 Score = 61.6 bits (148), Expect = 2e-09 Identities = 36/89 (40%), Positives = 49/89 (55%), Gaps = 2/89 (2%) Frame = -2 Query: 648 WMAPELL-NGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L +G S S DV+SFG+ LWEI T +PY ++ +++N Sbjct: 1218 WMAPESLKDGIFSTAS---DVWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNG-HLDY 1273 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEV 388 PE CD + R M CW +P +RPSF E+ Sbjct: 1274 PEGCDYQLREFMSLCWHRDPKMRPSFLEI 1302
>TIE1_MOUSE (Q06806) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1134 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/95 (40%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + K DV+SFG+ LWEI++ G PY M C + + R P Sbjct: 1015 WMAIESLNYSV--YTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQG-YRMEQP 1071 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 CD E LM QCW P RP F ++ +L M Sbjct: 1072 RNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1106
>TIE1_HUMAN (P35590) Tyrosine-protein kinase receptor Tie-1 precursor (EC| 2.7.10.1) Length = 1138 Score = 61.6 bits (148), Expect = 2e-09 Identities = 38/95 (40%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + K DV+SFG+ LWEI++ G PY M C + + R P Sbjct: 1019 WMAIESLNYSV--YTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQG-YRMEQP 1075 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 CD E LM QCW P RP F ++ +L M Sbjct: 1076 RNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1110
>INSRR_CAVPO (P14617) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 61.6 bits (148), Expect = 2e-09 Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L DV+SFG+ LWEI+T E+PY + ++ +++ + + Sbjct: 1158 WMAPESLKDGIFTTHS--DVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL- 1214 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 E C + + LM CW NP +RP+FT++ + ++ Sbjct: 1215 EDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQ 1247
>INSR_MOUSE (P15208) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1372 Score = 61.2 bits (147), Expect = 2e-09 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE L S D++SFG+ LWEI + E+PY + ++ +++ P P Sbjct: 1192 WMSPESLKDGVFTASS--DMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP-P 1248 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 + C LM CW NP +RP+F E+ + L+ Sbjct: 1249 DNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1281
>VGFR1_MOUSE (P35969) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2) Length = 1333 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/107 (34%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + S K DV+S+G+ LWEI + G PY + + +R P Sbjct: 1065 WMAPESI--FDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTP 1122 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 E PE +M CW +P RP F E+ ++L +LQ+ VQ G Sbjct: 1123 EYATPEIYQIMLDCWHKDPKERPRFAELVEKL---GDLLQANVQQDG 1166
>INSR_RAT (P15127) Insulin receptor precursor (EC 2.7.10.1) (IR) [Contains:| Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1383 Score = 61.2 bits (147), Expect = 2e-09 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE L S D++SFG+ LWEI + E+PY + ++ +++ P P Sbjct: 1203 WMSPESLKDGVFTASS--DMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDP-P 1259 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 + C LM CW NP +RP+F E+ + L+ Sbjct: 1260 DNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1292
>VGFR1_RAT (P53767) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) Length = 1336 Score = 61.2 bits (147), Expect = 2e-09 Identities = 37/107 (34%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + S K DV+S+G+ LWEI + G PY + + +R P Sbjct: 1065 WMAPESI--FDKVYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRTP 1122 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 E PE +M CW +P RP F E+ ++L +LQ+ VQ G Sbjct: 1123 EYATPEIYQIMLDCWHKDPKERPRFAELVEKL---GDLLQANVQQDG 1166
>ABL1_CAEEL (P03949) Tyrosine-protein kinase abl-1 (EC 2.7.10.2)| Length = 1224 Score = 61.2 bits (147), Expect = 2e-09 Identities = 34/88 (38%), Positives = 48/88 (54%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + + S K DV++FG+ LWEI T G PY + + G ++ N R P Sbjct: 474 WTAPEGL--AFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYG-LLENGFRMDGP 530 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 + C P LM QCW+ +P RP F ++ Sbjct: 531 QGCPPSVYRLMLQCWNWSPSDRPRFRDI 558
>TIE2_BRARE (O73791) Tyrosine-protein kinase receptor Tie-2 precursor (EC| 2.7.10.1) Length = 1116 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 1/102 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + DV+S+G+ LWE+++ G PY M C + + R P Sbjct: 996 WMAIESLNYSVYTTNS--DVWSYGVLLWEVVSLGGTPYCGMTCAELYEKLPLG-FRLEKP 1052 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 CD E LM+QCW P RPSF+++ L ++ ML+ R Sbjct: 1053 LNCDDEVYELMQQCWREKPFERPSFSQI---LLSLGRMLEER 1091
>FAK2_HUMAN (Q14289) Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal| adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinas Length = 1009 Score = 60.8 bits (146), Expect = 3e-09 Identities = 32/88 (36%), Positives = 50/88 (56%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE +N R + DV+ F + +WEIL+ G++P+ + +IG ++ R P P Sbjct: 591 WMSPESIN--FRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIG-VLEKGDRLPKP 647 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 + C P LM +CW +P RP FTE+ Sbjct: 648 DLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
>TIE2_MOUSE (Q02858) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen) Length = 1122 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + DV+S+G+ LWEI++ G PY M C + + R P Sbjct: 1002 WMAIESLNYSVYTTNS--DVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQG-YRLEKP 1058 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 CD E LM QCW P RPSF ++ L +++ ML+ R Sbjct: 1059 LNCDDEVYDLMRQCWREKPYERPSFAQI---LVSLNRMLEER 1097
>IGF1R_XENLA (O73798) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (xIGF-1R) (xIGFR) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1358 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE L + DV+SFG+ LWEI T E+PY M ++ ++ L P Sbjct: 1174 WMSPESLKDGVFTTNS--DVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEK-P 1230 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 + C LM CW NP +RPSF E+ ++ Sbjct: 1231 DNCPDMLFELMRMCWQFNPKMRPSFLEIISSIK 1263
>TIE2_BOVIN (Q06807) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (CD202b antigen) Length = 1125 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + DV+S+G+ LWEI++ G PY M C + + R P Sbjct: 1005 WMAIESLNYSVYTTNS--DVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQG-YRLEKP 1061 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 CD E LM QCW P RPSF ++ L +++ ML+ R Sbjct: 1062 LNCDDEVYDLMRQCWREKPYERPSFAQI---LVSLNRMLEER 1100
>ACK1_MOUSE (O54967) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1)| (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2) Length = 1055 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + S D + FG+ LWE+ T G+EP+ ++ I+ I R P P Sbjct: 296 WCAPESLK--TRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRP 353 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C + +M QCW+ P+ RP+F + D L Sbjct: 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
>ACK1_HUMAN (Q07912) Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine| kinase non-receptor protein 2) Length = 1036 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + S D + FG+ LWE+ T G+EP+ ++ I+ I R P P Sbjct: 296 WCAPESLK--TRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRP 353 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C + +M QCW+ P+ RP+F + D L Sbjct: 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
>VGFR1_HUMAN (P17948) Vascular endothelial growth factor receptor 1 precursor (EC| 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1) Length = 1338 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/107 (34%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + S K DV+S+G+ LWEI + G PY + + +R P Sbjct: 1065 WMAPESI--FDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAP 1122 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 E PE +M CW +P RP F E+ ++L +LQ+ VQ G Sbjct: 1123 EYSTPEIYQIMLDCWHRDPKERPRFAELVEKL---GDLLQANVQQDG 1166
>TIE2_HUMAN (Q02763) Angiopoietin-1 receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen) Length = 1124 Score = 60.8 bits (146), Expect = 3e-09 Identities = 39/102 (38%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E LN S + DV+S+G+ LWEI++ G PY M C + + R P Sbjct: 1004 WMAIESLNYSVYTTNS--DVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQG-YRLEKP 1060 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 CD E LM QCW P RPSF ++ L +++ ML+ R Sbjct: 1061 LNCDDEVYDLMRQCWREKPYERPSFAQI---LVSLNRMLEER 1099
>SRMS_HUMAN (Q9H3Y6) Tyrosine-protein kinase Srms (EC 2.7.10.2)| Length = 488 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 W APE N RV S+K DV+SFG+ L E+ T G+ PY M + I+ R P Sbjct: 392 WTAPEAAN---YRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRG-YRLPR 447 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 P C E +LM +CW ++P+ RPSF + ++L A+ Sbjct: 448 PAACPAEVYVLMLECWRSSPEERPSFATLREKLHAI 483
>VGFR2_BRARE (Q8AXB3) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Receptor tyrosine kinase flk-1) Length = 1302 Score = 60.8 bits (146), Expect = 3e-09 Identities = 37/107 (34%), Positives = 51/107 (47%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + DV+SFG+ +WEI + G PY +H + R P Sbjct: 1046 WMAPEAI--FDKIYTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEEFCCRLKEGTRMKAP 1103 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 E E M CW P RP+FTE+ +RL +LQ+ VQ G Sbjct: 1104 EYSSSEIYQTMLDCWHGEPSQRPTFTELVERL---GDLLQASVQQEG 1147
>MATK_HUMAN (P42679) Megakaryocyte-associated tyrosine-protein kinase (EC| 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase) Length = 507 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + + K DV+SFG+ LWE+ + G PY M + V R P Sbjct: 390 WTAPEALK--HGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEV-SEAVEKGYRMEPP 446 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C +LM CW A P RP F ++ ++L Sbjct: 447 EGCPGPVHVLMSSCWEAEPARRPPFRKLAEKL 478
>ACK2_BOVIN (O02742) Activated CDC42 kinase 2 (EC 2.7.10.2) (ACK-2)| Length = 747 Score = 60.8 bits (146), Expect = 3e-09 Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + S D + FG+ LWE+ T G+EP+ ++ I+ I R P P Sbjct: 296 WCAPESLK--TRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRP 353 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C + +M QCW+ P+ RP+F + D L Sbjct: 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
>KSYK_MOUSE (P48025) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 60.5 bits (145), Expect = 4e-09 Identities = 35/93 (37%), Positives = 50/93 (53%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + S K DV+SFG+ +WE + G++PY M G+ + ++ R P Sbjct: 532 WYAPECIN--YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK-GSEVTAMLEKGERMGCP 588 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 C E LM CW+ + + RP FT V RLR Sbjct: 589 AGCPREMYDLMNLCWTYDVENRPGFTAVELRLR 621
>RON_HUMAN (Q04912) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain] Length = 1400 Score = 60.5 bits (145), Expect = 4e-09 Identities = 40/110 (36%), Positives = 60/110 (54%), Gaps = 3/110 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + R + K DV+SFG+ LWE+LT G PY ++ + + R P P Sbjct: 1253 WMALESLQ--TYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGR-RLPQP 1309 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL-RAMSAMLQSR-VQAPGS 328 E C +M+QCW A+P +RP+F + + + +SA+L VQ P + Sbjct: 1310 EYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLPAT 1359
>HCK_HUMAN (P08631) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p59-HCK/p60-HCK) (Hemopoietic cell kinase) Length = 525 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/104 (36%), Positives = 51/104 (49%), Gaps = 1/104 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N S + K DV+SFGI L EI+T G PY M +I + R P P Sbjct: 422 WTAPEAINFGSFTI--KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL-ERGYRMPRP 478 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 E C E +M +CW P+ RP+F + L +S+ Q Sbjct: 479 ENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQ 522
>ANKK1_MOUSE (Q8BZ25) Ankyrin repeat and protein kinase domain-containing| protein 1 (EC 2.7.11.1) Length = 745 Score = 60.1 bits (144), Expect = 6e-09 Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 7/113 (6%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 ++ PE+ ++ + DV+SF I +WEILT ++PYA ++ II + +RP + + Sbjct: 202 YIPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKKPYAGLNMMTIIIRVA-AGMRPSLQD 260 Query: 468 TCDPEWR-------ILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 D EW LM++CW +P RP F V + ++ QS + PG Sbjct: 261 VSD-EWPEEVHQMVNLMKRCWDQDPKKRPCFLNVAVETDMLLSLFQSPMTDPG 312
>KIN15_CAEEL (P34891) Receptor-like tyrosine-protein kinase kin-15 precursor (EC| 2.7.10.1) Length = 488 Score = 60.1 bits (144), Expect = 6e-09 Identities = 30/90 (33%), Positives = 56/90 (62%), Gaps = 1/90 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE++ + +EK DV+S+G++L+E+ + GE PY+N+ + +V + + P+P Sbjct: 364 WMAPEVMR--EGKCTEKSDVWSYGVSLYEMFSLGELPYSNVSNSDVFEHVVQGN-QLPMP 420 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTD 382 + C P+ M+Q W+ + RPSF++ + Sbjct: 421 QYCHPKMYDRMKQFWNFDATFRPSFSKCVE 450
>FPS_AVISP (P00541) Tyrosine-protein kinase transforming protein Fps (EC| 2.7.10.2) Length = 533 Score = 60.1 bits (144), Expect = 6e-09 Identities = 38/95 (40%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PYAN+ + +R P Sbjct: 437 WTAPEALN--YGRYSSESDVWSFGILLWEAFSLGAVPYANLS-NQQTREAIEQGVRLEPP 493 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C + LM++CW +P RPSF V L A+ Sbjct: 494 EQCPEDVYRLMQRCWEYDPRRRPSFGAVHQDLIAI 528
>INSRR_MOUSE (Q9WTL4) Insulin receptor-related protein precursor (EC 2.7.10.1)| (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] Length = 1300 Score = 60.1 bits (144), Expect = 6e-09 Identities = 31/93 (33%), Positives = 51/93 (54%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L DV+SFG+ LWEI+T E+PY + ++ +++ + + Sbjct: 1158 WMAPESLKDGIFTTHS--DVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL- 1214 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 E C + + LM CW +P +RP+F + DR++ Sbjct: 1215 ENCPIQLQELMRLCWQHSPRLRPTFVHILDRIQ 1247
>KIN16_CAEEL (P34892) Receptor-like tyrosine-protein kinase kin-16 precursor (EC| 2.7.10.1) Length = 495 Score = 60.1 bits (144), Expect = 6e-09 Identities = 33/90 (36%), Positives = 53/90 (58%), Gaps = 1/90 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE + + + +EK DV+SFGI L+EI T G+ PY ++ I +++ R P P Sbjct: 366 WMSPEAFD--TMKFTEKSDVWSFGICLYEIFTLGQLPYPDVPSERIYE-YMHSGRRCPQP 422 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTD 382 + C E LM+ CW P++RP+F+ + Sbjct: 423 QHCHVELYDLMKLCWHEKPELRPNFSNCVE 452
>ABL_MLVAB (P00521) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 746 Score = 59.7 bits (143), Expect = 7e-09 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + ++ S K DV++FG+ LWEI T G PY + + ++ R P Sbjct: 291 WTAPESL--AYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE-LLEKDYRMERP 347 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C + LM CW NP RPSF E+ M Sbjct: 348 EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 382
>ABL1_HUMAN (P00519) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1130 Score = 59.7 bits (143), Expect = 7e-09 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + ++ S K DV++FG+ LWEI T G PY + + ++ R P Sbjct: 405 WTAPESL--AYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE-LLEKDYRMERP 461 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C + LM CW NP RPSF E+ M Sbjct: 462 EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 496
>ABL1_MOUSE (P00520) Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2)| (p150) (c-ABL) (Abelson murine leukemia viral oncogene homolog 1) Length = 1123 Score = 59.7 bits (143), Expect = 7e-09 Identities = 35/95 (36%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + ++ S K DV++FG+ LWEI T G PY + + ++ R P Sbjct: 405 WTAPESL--AYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE-LLEKDYRMERP 461 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C + LM CW NP RPSF E+ M Sbjct: 462 EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETM 496
>FGFR4_HUMAN (P22455) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (CD334 antigen) Length = 802 Score = 59.3 bits (142), Expect = 9e-09 Identities = 37/93 (39%), Positives = 49/93 (52%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFGI LWEI T G PY + + ++ R Sbjct: 655 WMAPEAL---FDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFS-LLREGHRMDR 710 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C PE LM +CW A P RP+F ++ + L Sbjct: 711 PPHCPPELYGLMRECWHAAPSQRPTFKQLVEAL 743
>BTKL_DROME (P08630) Tyrosine-protein kinase Btk29A (EC 2.7.10.2) (Dsrc28C)| Length = 786 Score = 59.3 bits (142), Expect = 9e-09 Identities = 32/99 (32%), Positives = 55/99 (55%), Gaps = 1/99 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W PE+LN +R S K DV+++G+ +WEI T G+ PY + ++ + + P Sbjct: 689 WAPPEVLN--YTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEK-P 745 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 ++C E +M+ CWS P+ RP+F + D+L ++ L Sbjct: 746 KSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTL 784
>VGFR3_RAT (Q91ZT1) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 59.3 bits (142), Expect = 9e-09 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + DV+SFG+ LWEI + G PY + + + R P Sbjct: 1080 WMAPESI--FDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAP 1137 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E P R +M+ CWS +P RP+F+++ + L Sbjct: 1138 ELATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169
>VGFR3_MOUSE (P35917) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1363 Score = 59.3 bits (142), Expect = 9e-09 Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + DV+SFG+ LWEI + G PY + + + R P Sbjct: 1080 WMAPESI--FDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAP 1137 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E P R +M+ CWS +P RP+F+++ + L Sbjct: 1138 ELATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169
>HCK_RAT (P50545) Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK)| (Hemopoietic cell kinase) Length = 502 Score = 59.3 bits (142), Expect = 9e-09 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N S + K DV+SFGI L EI+T G PY M +I + + R P P Sbjct: 399 WTAPEAINFGSFTI--KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL-EHGYRMPRP 455 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 + C E +M +CW P+ RP+F + L +S+ Q Sbjct: 456 DNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQYQ 499
>TYRO3_RAT (P55146) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase SKY) Length = 880 Score = 59.3 bits (142), Expect = 9e-09 Identities = 35/86 (40%), Positives = 49/86 (56%), Gaps = 1/86 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W+A E L + V DV++FG+ +WEI+T G+ PYA + I +++ + P Sbjct: 688 WLALESLADNLYTVHS--DVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLISGNRLKQPP 745 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFT 394 E C E LM QCWSA+P RPSFT Sbjct: 746 E-CMEEVYDLMYQCWSADPKQRPSFT 770
>FPS_DROME (P18106) Tyrosine-protein kinase Fps85D (EC 2.7.10.2) (dFer)| Length = 1325 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN + + DV+S+GI +WEI + G+ PY+ M + ++ R P P Sbjct: 1226 WTAPEALN--FGKYTSLCDVWSYGILMWEIFSKGDTPYSGM-TNSRARERIDTGYRMPTP 1282 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQS 349 ++ E LM QCW+A+ + RP F E+ + + A+ L + Sbjct: 1283 KSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDN 1323
>INSR_HUMAN (P06213) Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220| antigen) [Contains: Insulin receptor alpha subunit; Insulin receptor beta subunit] Length = 1382 Score = 58.9 bits (141), Expect = 1e-08 Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L S D++SFG+ LWEI + E+PY + ++ +++ P Sbjct: 1202 WMAPESLKDGVFTTSS--DMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQ-P 1258 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 + C LM CW NP +RP+F E+ + L+ Sbjct: 1259 DNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK 1291
>LCK_SAISC (Q95KR7) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) Length = 508 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/85 (41%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + + K DV+SFGI + EI+T G PY M +I + R P P Sbjct: 405 WTAPEAINYGTFTI--KSDVWSFGILMTEIVTHGRIPYPGMTNPEVIQNL-ERGYRMPRP 461 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 + C E LM QCW PD RP+F Sbjct: 462 DNCPEELYKLMMQCWRERPDDRPTF 486
>IGF1R_HUMAN (P08069) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 recepto Length = 1367 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 2/94 (2%) Frame = -2 Query: 648 WMAPELL-NGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WM+PE L +G + S DV+SFG+ LWEI T E+PY + ++ ++ L Sbjct: 1178 WMSPESLKDGVFTTYS---DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK- 1233 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 P+ C LM CW NP +RPSF E+ ++ Sbjct: 1234 PDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK 1267
>KSYK_PIG (Q00655) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) [Contains: 72 kDa tyrosine-protein kinase SYK; 40 kDa tyrosine-protein kinase SYK] Length = 628 Score = 58.9 bits (141), Expect = 1e-08 Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + S K DV+SFG+ +WE + G++PY M G+ + ++ R P Sbjct: 531 WYAPECIN--YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK-GSEVSAMLEKGERMGCP 587 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 C E LM CW+ + + RP F V RLR Sbjct: 588 PGCPREMYELMTLCWTYDVENRPGFVAVELRLR 620
>LCK_CHICK (P42683) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (Protein-tyrosine kinase C-TKL) (p56tk1) Length = 507 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/85 (41%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + + K DV+SFGI L EI+T G PY M +I + R P P Sbjct: 404 WTAPEAINYGTFTI--KSDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNL-ERGYRMPQP 460 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 + C E LM QCW P+ RP+F Sbjct: 461 DNCPQELYELMMQCWKEQPEERPTF 485
>EPHA2_HUMAN (P29317) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) Length = 976 Score = 58.9 bits (141), Expect = 1e-08 Identities = 36/108 (33%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + S + + DV+SFGI +WE++T GE PY + ++ I N+ R P P Sbjct: 783 WTAPEAI--SYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAI-NDGFRLPTP 839 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPGS 328 C LM QCW RP F ++ ++L ++AP S Sbjct: 840 MDCPSAIYQLMMQCWQQERARRPKFADIV-------SILDKLIRAPDS 880
>HCK_MOUSE (P08103) Tyrosine-protein kinase HCK (EC 2.7.10.2)| (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK) Length = 523 Score = 58.9 bits (141), Expect = 1e-08 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N S + K DV+SFGI L EI+T G PY M +I + + R P P Sbjct: 420 WTAPEAINFGSFTI--KSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRAL-EHGYRMPRP 476 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 + C E +M +CW P+ RP+F + L +S+ Q Sbjct: 477 DNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQYQ 520
>TYRO3_MOUSE (P55144) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3) Length = 880 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/86 (40%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W+A E L + V DV++FG+ +WEI+T G+ PYA + I ++ + P Sbjct: 688 WLALESLADNLYTVHS--DVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPP 745 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFT 394 E C E LM QCWSA+P RPSFT Sbjct: 746 E-CMEEVYDLMYQCWSADPKQRPSFT 770
>INSR_AEDAE (Q93105) Insulin-like receptor precursor (EC 2.7.10.1) (MIR)| [Contains: Insulin-like receptor alpha chain; Insulin-like receptor beta chain] Length = 1390 Score = 58.5 bits (140), Expect = 2e-08 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L S DVFS+G+ LWE+ T +PY + ++ +++ + P Sbjct: 1205 WMAPESLKDGI--FSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMER-P 1261 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C LM +CW P RP+F E+ L Sbjct: 1262 ENCPDNLYNLMRRCWQHRPTARPTFMEIISEL 1293
>IGF1R_MOUSE (Q60751) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1373 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE L DV+SFG+ LWEI T E+PY + ++ ++ L P Sbjct: 1180 WMSPESLKDGVFTTHS--DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-P 1236 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 + C LM CW NP +RPSF E+ ++ Sbjct: 1237 DNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIK 1269
>KSYK_HUMAN (P43405) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 635 Score = 58.5 bits (140), Expect = 2e-08 Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + S K DV+SFG+ +WE + G++PY M G+ + ++ R P Sbjct: 538 WYAPECIN--YYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK-GSEVTAMLEKGERMGCP 594 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 C E LM CW+ + + RP F V RLR Sbjct: 595 AGCPREMYDLMNLCWTYDVENRPGFAAVELRLR 627
>RIPK3_HUMAN (Q9Y572) Receptor-interacting serine/threonine-protein kinase 3 (EC| 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) Length = 518 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/112 (31%), Positives = 54/112 (48%), Gaps = 8/112 (7%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPV-- 475 ++APEL + + S DV+SFGI +W +L G E + + N RP + Sbjct: 185 YLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAE 244 Query: 474 -----PETCDPE-WRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQA 337 PET E + LM+ CWS+ P RPSF E + + M+++ + A Sbjct: 245 LPQAGPETPGLEGLKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNA 296
>VGFR3_HUMAN (P35916) Vascular endothelial growth factor receptor 3 precursor (EC| 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4) Length = 1298 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/92 (34%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + DV+SFG+ LWEI + G PY + + + R P Sbjct: 1080 WMAPESI--FDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLRDGTRMRAP 1137 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E P R +M CWS +P RP+F+E+ + L Sbjct: 1138 ELATPAIRRIMLNCWSGDPKARPAFSELVEIL 1169
>IGF1R_RAT (P24062) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] Length = 1370 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE L DV+SFG+ LWEI T E+PY + ++ ++ L P Sbjct: 1179 WMSPESLKDGVFTTHS--DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-P 1235 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 + C LM CW NP +RPSF E+ ++ Sbjct: 1236 DNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIK 1268
>ROR1_MOUSE (Q9Z139) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1) Length = 937 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM PE + + S D++SFG+ LWEI + G +PY +I + L P Sbjct: 658 WMPPEAI--MYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLP-CS 714 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAM 358 E C P LM +CW+ P RP F ++ RLR+ + Sbjct: 715 EDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGL 752
>ROR1_HUMAN (Q01973) Tyrosine-protein kinase transmembrane receptor ROR1| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) Length = 937 Score = 58.5 bits (140), Expect = 2e-08 Identities = 33/98 (33%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM PE + + S D++SFG+ LWEI + G +PY +I + L P Sbjct: 658 WMPPEAI--MYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLP-CS 714 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAM 358 E C P LM +CW+ P RP F ++ RLR+ + Sbjct: 715 EDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGL 752
>EPHA2_MOUSE (Q03145) Ephrin type-A receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2) Length = 977 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/108 (32%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + S + + DV+S+GI +WE++T GE PY + ++ I N+ R P P Sbjct: 784 WTAPEAI--SYRKFTSASDVWSYGIVMWEVMTYGERPYWELSNHEVMKAI-NDGFRLPTP 840 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPGS 328 C LM QCW RP F ++ ++L ++AP S Sbjct: 841 MDCPSAIYQLMMQCWQQERSRRPKFADIV-------SILDKLIRAPDS 881
>ABL2_HUMAN (P42684) Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine| leukemia viral oncogene homolog 2) (Tyrosine kinase ARG) Length = 1182 Score = 58.5 bits (140), Expect = 2e-08 Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + + S K DV++FG+ LWEI T G PY + + ++ R P Sbjct: 451 WTAPESL--AYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYD-LLEKGYRMEQP 507 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C P+ LM CW +P RPSF E M Sbjct: 508 EGCPPKVYELMRACWKWSPADRPSFAETHQAFETM 542
>LIMK2_RAT (P53670) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 58.5 bits (140), Expect = 2e-08 Identities = 40/101 (39%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHC---GAIIGGIVNNSLRPP 478 WMAPE+LNG S E VDVFSFGI L EI+ + YA+ C G V Sbjct: 512 WMAPEMLNGKS--YDETVDVFSFGIVLCEIIG--QVYADPDCLPRTLDFGLNVKLFWEKF 567 Query: 477 VPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 VP C P + L C P+ RP+F+++ D A+S L Sbjct: 568 VPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFL 608
>LIMK2_MOUSE (O54785) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 58.5 bits (140), Expect = 2e-08 Identities = 40/101 (39%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHC---GAIIGGIVNNSLRPP 478 WMAPE+LNG S E VDVFSFGI L EI+ + YA+ C G V Sbjct: 512 WMAPEMLNGKS--YDETVDVFSFGIVLCEIIG--QVYADPDCLPRTLDFGLNVKLFWEKF 567 Query: 477 VPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 VP C P + L C P+ RP+F+++ D A+S L Sbjct: 568 VPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEALSLFL 608
>EPHB3_XENLA (Q91735) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor TCK) Length = 974 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 4/110 (3%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + S + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 780 WTAPEAI--SYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLPP-P 836 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVT---DRLRAMSAMLQSRVQAPG 331 C LM CW + ++RP F+++ D+L +A L +V +PG Sbjct: 837 MDCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDKLIRNAASL--KVTSPG 884
>IGF1R_BOVIN (Q05688) Insulin-like growth factor 1 receptor precursor (EC| 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (F Length = 640 Score = 58.5 bits (140), Expect = 2e-08 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE L DV+SFG+ LWEI T E+PY + ++ ++ L P Sbjct: 451 WMSPESLKDGVFTTHS--DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-P 507 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 + C LM CW NP +RPSF E+ ++ Sbjct: 508 DNCPDMLFELMRMCWQYNPKMRPSFLEIISSVK 540
>TYRO3_HUMAN (Q06418) Tyrosine-protein kinase receptor TYRO3 precursor (EC| 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase DTK) (Protein-tyrosine kinase byk) Length = 890 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 1/86 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W+A E L + V DV++FG+ +WEI+T G+ PYA + I ++ + P Sbjct: 698 WLALESLADNLYTVQS--DVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPP 755 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFT 394 E C + LM QCWSA+P RPSFT Sbjct: 756 E-CMEDVYDLMYQCWSADPKQRPSFT 780
>EPHAA_HUMAN (Q5JZY3) Ephrin type-A receptor 10 precursor (EC 2.7.10.1)| Length = 1008 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L S DV+SFGI +WE++ GE PY +M +I V + R P P Sbjct: 812 WAAPETLQ--FGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKA-VEDGFRLPPP 868 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW +P RP F+++ L M Sbjct: 869 RNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKM 903
>EPHA6_RAT (P54758) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 58.2 bits (139), Expect = 2e-08 Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + S DV+S+GI +WE+++ GE PY M +I I R P P Sbjct: 841 WTAPEAI--AYRKFSSASDVWSYGIVMWEVMSYGERPYWEMSNQDVILSI-EEGYRLPAP 897 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C P LM CW + RP FT++ L Sbjct: 898 MGCPPSLHQLMLHCWQKERNHRPKFTDIVSFL 929
>EPHB3_MOUSE (P54754) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4) Length = 993 Score = 58.2 bits (139), Expect = 2e-08 Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 4/109 (3%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY +M +I + + PP P Sbjct: 799 WTAPEAI--AYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPP-P 855 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVT---DRLRAMSAMLQSRVQAP 334 C LM CW + ++RP F+++ D+L +A L+ AP Sbjct: 856 MDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVTASAP 904
>ROR2_HUMAN (Q01974) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) Length = 943 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + S D++S+G+ LWE+ + G +PY ++ I N + P P Sbjct: 658 WMAPEAI--MYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLP-CP 714 Query: 471 ETCDPEW-RILMEQCWSANPDIRPSFTEVTDRLRA 370 + C P W LM +CW+ P RP F ++ RLRA Sbjct: 715 DDC-PAWVYALMIECWNEFPSRRPRFKDIHSRLRA 748
>FGFR1_XENLA (P22182) Fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) Length = 812 Score = 57.8 bits (138), Expect = 3e-08 Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 5/101 (4%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L R+ + + DV+SFG+ LWEI T G PY + + ++ R Sbjct: 660 WMAPEAL---FDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFK-LLKEGHRMDK 715 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVT---DRLRAMSA 361 P C E ++M+ CW A P RP+F ++ DR+ A+S+ Sbjct: 716 PTNCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRILALSS 756
>ERBB3_RAT (Q62799) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) Length = 1339 Score = 57.8 bits (138), Expect = 3e-08 Identities = 33/113 (29%), Positives = 61/113 (53%), Gaps = 6/113 (5%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E ++ + + + DV+S+G+ +WE++T G EPYA + A I ++ R P Sbjct: 875 WMALESIH--FGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRL-AEIPDLLEKGERLAQP 931 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSA-----MLQSRVQAPGS 328 + C + ++M +CW + +IRP+F E+ + M+ ++ R PG+ Sbjct: 932 QICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRASGPGT 984
>FGFR1_CHICK (P21804) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) Length = 819 Score = 57.8 bits (138), Expect = 3e-08 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 2/103 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L R+ + + DV+SFG+ LWEI T G PY + + ++ R Sbjct: 664 WMAPEAL---FDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFK-LLKEGHRMDK 719 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 P C E ++M CW A P RP+F ++ + L + AM ++ Sbjct: 720 PSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQ 762
>ABL_FSVHY (P10447) Tyrosine-protein kinase transforming protein Abl (EC| 2.7.10.2) (V-abl) Length = 439 Score = 57.8 bits (138), Expect = 3e-08 Identities = 33/88 (37%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + ++ S K DV++FG+ LWEI T G PY + + ++ R P Sbjct: 354 WTAPESL--AYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYE-LLEKDYRMERP 410 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 E C + LM CW NP RP+F E+ Sbjct: 411 EGCPEKVYELMRACWQWNPSDRPAFAEI 438
>BLK_HUMAN (P51451) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 504 Score = 57.8 bits (138), Expect = 3e-08 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 2/86 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE ++ + K DV+SFG+ L E++T G PY M +I + R P P Sbjct: 400 WTAPEAIHFGVFTI--KADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNL-ERGYRMPRP 456 Query: 471 ETCDPE-WRILMEQCWSANPDIRPSF 397 +TC PE +R ++ +CW + P+ RP+F Sbjct: 457 DTCPPELYRGVIAECWRSRPEERPTF 482
>KSYK_RAT (Q64725) Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine| kinase) Length = 629 Score = 57.4 bits (137), Expect = 4e-08 Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + S K DV+SFG+ +WE + G++PY M G+ + ++ R P Sbjct: 532 WYAPECIN--YFKFSSKSDVWSFGVLMWEAFSYGQKPYRGMK-GSEVTAMLEKGERMGCP 588 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 C E LM CW+ + + RP F V RLR Sbjct: 589 PGCPREMYDLMFLCWTYDVENRPGFAAVELRLR 621
>ERBB3_MOUSE (Q61526) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Glial growth factor receptor) Length = 1339 Score = 57.4 bits (137), Expect = 4e-08 Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 6/112 (5%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E ++ + + + DV+S+G+ +WE++T G EPYA + A I ++ R P Sbjct: 875 WMALESIH--FGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRL-AEIPDLLEKGERLAQP 931 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSA-----MLQSRVQAPG 331 + C + ++M +CW + +IRP+F E+ + M+ ++ R PG Sbjct: 932 QICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRASGPG 983
>LIMK2_HUMAN (P53671) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 638 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/101 (38%), Positives = 51/101 (50%), Gaps = 3/101 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHC---GAIIGGIVNNSLRPP 478 WMAPE+LNG S E VD+FSFGI L EI+ + YA+ C G V Sbjct: 512 WMAPEMLNGKS--YDETVDIFSFGIVLCEIIG--QVYADPDCLPRTLDFGLNVKLFWEKF 567 Query: 477 VPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 VP C P + L C P+ RP+F+++ D A+S L Sbjct: 568 VPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYL 608
>FPS_FUJSV (P00530) Tyrosine-protein kinase transforming protein FPS (EC| 2.7.10.2) Length = 873 Score = 57.4 bits (137), Expect = 4e-08 Identities = 37/95 (38%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN S + DV+SFGI LWE + G PYAN+ + +R P Sbjct: 777 WTAPEALN--YGWYSSESDVWSFGILLWEAFSLGAVPYANLS-NQQTREAIEQGVRLEPP 833 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C + LM++CW +P RPSF V L A+ Sbjct: 834 EQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIAI 868
>MET_HUMAN (P08581) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1249 WMALESLQ--TQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1305 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1306 EYCPDPLYEVMLK-CWHPKAEMRPSFSELVSRISAI 1340
>FGFR4_RAT (Q498D6) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) Length = 800 Score = 57.0 bits (136), Expect = 5e-08 Identities = 36/93 (38%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFGI LWEI T G PY + + ++ R Sbjct: 653 WMAPEAL---FDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFS-LLREGHRMER 708 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C E LM +CW A P RP+F ++ + L Sbjct: 709 PPNCPSELYGLMRECWHAAPSQRPTFKQLVEAL 741
>MET_CANFA (Q75ZY9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1250 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1306 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1307 EYCPDPLYEVMLK-CWHPRAELRPSFSELVSRISAI 1341
>EPHA6_MOUSE (Q62413) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/92 (34%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + S D +S+GI +WE+++ GE PY M +I I R P P Sbjct: 841 WTAPEAI--AYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSI-EEGYRLPAP 897 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C P + LM CW + RP FT++ L Sbjct: 898 MGCPPSLQQLMLHCWQKERNHRPKFTDIVSFL 929
>VGFR2_MOUSE (P35918) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) Length = 1367 Score = 57.0 bits (136), Expect = 5e-08 Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + DV+SFG+ LWEI + G PY + + R P Sbjct: 1069 WMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1126 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 + PE M CW +P+ RPSF+E+ + L +LQ+ Q G Sbjct: 1127 DYTTPEMYQTMLDCWHEDPNQRPSFSELVEHL---GNLLQANAQQDG 1170
>EPHB1_RAT (P09759) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (ELK) Length = 984 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 790 WTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPP-P 846 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP F E+ + L M Sbjct: 847 MDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>EPHB1_HUMAN (P54762) Ephrin type-B receptor 1 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK) Length = 984 Score = 57.0 bits (136), Expect = 5e-08 Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 790 WTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPP-P 846 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP F E+ + L M Sbjct: 847 MDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
>FGFR2_DROME (Q09147) Fibroblast growth factor receptor homolog 2 precursor (EC| 2.7.10.1) (Protein breathless) (dFGF-R1) Length = 1052 Score = 57.0 bits (136), Expect = 5e-08 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L + + DV+S+G+ LWEI+T G++PY ++ + + R P Sbjct: 907 WMAPESLQ--EKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKP 964 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTD 382 C ++M QCW RP+F E+ + Sbjct: 965 AKCSLNIYVVMRQCWHFESCARPTFAELVE 994
>MET_PIG (Q2QLE0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1249 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1305 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1306 EYCPDPLYEVMLK-CWHPRAELRPSFSELVSRISAI 1340
>MET_HORSE (Q2QLA9) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1249 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1305 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1306 EYCPDPLYEVMLK-CWHPKAELRPSFSELVSRISAI 1340
>MIPR_LYMST (Q25410) Putative molluscan insulin-related peptide(s) receptor| precursor (EC 2.7.10.1) [Contains: Putative molluscan insulin-related peptide(s) receptor alpha chain; Putative molluscan insulin-related peptide(s) receptor beta chain] Length = 1607 Score = 56.6 bits (135), Expect = 6e-08 Identities = 31/93 (33%), Positives = 53/93 (56%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELL-NGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L +G + +S DV+S+G+ +WE++T +PY + ++ I + + + Sbjct: 1216 WMAPESLKDGVFTSLS---DVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFISDGYIME-L 1271 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 PE C E LM+ CW+ P+ RP+F + + L Sbjct: 1272 PENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYL 1304
>MET_PONPY (Q2IBD8) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1249 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1305 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1306 EYCPDPLYEVMLK-CWHPKAEMRPSFSELVSRISAI 1340
>MET_PANTR (Q2QLF1) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1390 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1249 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1305 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1306 EYCPDPLYEVMLK-CWHPKAEMRPSFSELVSRISAI 1340
>FGFR1_MOUSE (P16092) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/103 (33%), Positives = 53/103 (51%), Gaps = 2/103 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L R+ + + DV+SFG+ LWEI T G PY + + ++ R Sbjct: 666 WMAPEAL---FDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFK-LLKEGHRMDK 721 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 P C E ++M CW A P RP+F ++ + L + A+ ++ Sbjct: 722 PSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ 764
>FGFR1_HUMAN (P11362) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen) Length = 822 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/103 (33%), Positives = 53/103 (51%), Gaps = 2/103 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L R+ + + DV+SFG+ LWEI T G PY + + ++ R Sbjct: 666 WMAPEAL---FDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFK-LLKEGHRMDK 721 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 P C E ++M CW A P RP+F ++ + L + A+ ++ Sbjct: 722 PSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ 764
>SRC42_DROME (Q9V9J3) Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Dsrc41)| Length = 517 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/85 (40%), Positives = 46/85 (54%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE N S+ S K DV+SFGI L E++T G PY M ++ V + R P P Sbjct: 412 WTAPEAAN--YSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQ-VEHGYRMPQP 468 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 C+P +M +CW +P RP+F Sbjct: 469 PNCEPRLYEIMLECWHKDPMRRPTF 493
>MET_OTOGA (Q2QLH6) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1250 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1306 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1307 EYCPDPLYEVMLK-CWHPKAEMRPSFSELVSRISAI 1341
>MET_MICMU (Q2QL89) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1382 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1250 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1306 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1307 EYCPDPLYEVMLK-CWHPKAEMRPSFSELVSRISAI 1341
>EPHA8_RAT (P29321) Ephrin type-A receptor 8 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EEK) (EPH- and ELK-related kinase) (Fragment) Length = 372 Score = 56.6 bits (135), Expect = 6e-08 Identities = 35/95 (36%), Positives = 45/95 (47%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + S DV+SFG+ +WE+L GE PY NM +I V R P P Sbjct: 171 WTAPEAI--AFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISS-VEEGYRLPAP 227 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + RP F+ V L A+ Sbjct: 228 MGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEAL 262
>CSK_HUMAN (P41240) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| (Protein-tyrosine kinase CYL) Length = 450 Score = 56.6 bits (135), Expect = 6e-08 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + S K DV+SFGI LWEI + G PY + ++ V + P Sbjct: 352 WTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPR-VEKGYKMDAP 408 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 + C P +M+ CW + +RPSF ++ ++L Sbjct: 409 DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQL 440
>CAD96_DROME (Q9VBW3) Tyrosine kinase receptor Cad96Ca precursor (EC 2.7.10.1)| (Cadherin 96Ca) (Tyrosine kinase receptor HD-14) Length = 773 Score = 56.6 bits (135), Expect = 6e-08 Identities = 35/92 (38%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + V K D++SFGI +WEI+T G PY + ++ V + R P Sbjct: 653 WMATESLYDNIFSV--KSDIWSFGILMWEIVTLGSTPYPGISAADVMRK-VRDGYRLEKP 709 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C E +M CWS +P RP F E+ L Sbjct: 710 EHCRRELYNIMYYCWSHDPQERPLFAEIIQML 741
>PGFRA_XENLA (P26619) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1087 Score = 56.6 bits (135), Expect = 6e-08 Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 1/102 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + DV+SFGI LWEI + G PY M + + + R P Sbjct: 861 WMAPESI--FDNLYTTLSDVWSFGILLWEIFSLGGTPYPGMIVDSTFYNKIKSGYRMAKP 918 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 + E +M +CW++ P+ RPSF ++D + ++ M R Sbjct: 919 DHATHEVYDIMVKCWNSEPEKRPSFRHLSDIVESLLPMEYKR 960
>RET_MOUSE (P35546) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1115 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/102 (36%), Positives = 52/102 (50%), Gaps = 1/102 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + DV+SFG+ LWEI+T G PY + + ++ R P Sbjct: 918 WMAIESL--FDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFN-LLKTGHRMERP 974 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 + C E LM QCW PD RP F +++ L M M++SR Sbjct: 975 DNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM--MVKSR 1014
>MET_CALMO (Q2QLC0) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1249 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1305 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1306 EYCPDPLYEVMLK-CWHPKAEMRPSFSELVSRISAI 1340
>MET_CALJA (Q2QLG5) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1381 Score = 56.6 bits (135), Expect = 6e-08 Identities = 34/96 (35%), Positives = 57/96 (59%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1249 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGR-RLLQP 1305 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C DP + ++++ CW ++RPSF+E+ R+ A+ Sbjct: 1306 EYCPDPLYEVMLK-CWHPKAEMRPSFSELVSRISAI 1340
>7LESS_DROVI (P20806) Protein sevenless (EC 2.7.10.1)| Length = 2594 Score = 56.6 bits (135), Expect = 6e-08 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 2/101 (1%) Frame = -2 Query: 648 WMAPE-LLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMA E L++G S S DV++FG+ WEI T G++PYA + ++ + R Sbjct: 2404 WMALESLVDGLFSTQS---DVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGG-RLQQ 2459 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQ 352 PE C + L+ QCW + P RPSF L+A+S+ L+ Sbjct: 2460 PERCPEKLYALLLQCWRSEPWERPSFKRCLSTLQALSSDLR 2500
>LIMK2_CHICK (P53666) LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2)| Length = 642 Score = 56.6 bits (135), Expect = 6e-08 Identities = 39/101 (38%), Positives = 50/101 (49%), Gaps = 3/101 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHC---GAIIGGIVNNSLRPP 478 WMAPE+LNG S E VD+FSFGI L EI+ + YA+ C G V Sbjct: 512 WMAPEMLNGQS--YDETVDIFSFGIVLCEIIG--QVYADPDCLPRTLDFGLNVKLFWEKF 567 Query: 477 VPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 VP C P + L C P+ RP F+++ D A+S L Sbjct: 568 VPADCPPAFFPLAAICCRLEPESRPPFSKLEDSFEALSLYL 608
>ERBB3_PONPY (Q5RB22) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) Length = 1342 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/96 (30%), Positives = 55/96 (57%), Gaps = 1/96 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E ++ + + + DV+S+G+ +WE++T G EPYA + A + ++ R P Sbjct: 877 WMALESIH--FGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRL-AEVPDLLEKGERLAQP 933 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMS 364 + C + ++M +CW + +IRP+F E+ + M+ Sbjct: 934 QICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMA 969
>ERBB3_HUMAN (P21860) Receptor tyrosine-protein kinase erbB-3 precursor (EC| 2.7.10.1) (c-erbB3) (Tyrosine kinase-type cell surface receptor HER3) Length = 1342 Score = 56.6 bits (135), Expect = 6e-08 Identities = 29/96 (30%), Positives = 55/96 (57%), Gaps = 1/96 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E ++ + + + DV+S+G+ +WE++T G EPYA + A + ++ R P Sbjct: 877 WMALESIH--FGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRL-AEVPDLLEKGERLAQP 933 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMS 364 + C + ++M +CW + +IRP+F E+ + M+ Sbjct: 934 QICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMA 969
>EPHA8_HUMAN (P29322) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3) Length = 1005 Score = 56.2 bits (134), Expect = 8e-08 Identities = 34/95 (35%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + S DV+SFG+ +WE+L GE PY NM +I V R P P Sbjct: 804 WTAPEAI--AFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISS-VEEGYRLPAP 860 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + RP F+++ L A+ Sbjct: 861 MGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDAL 895
>LTK_HUMAN (P29376) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| (Protein tyrosine kinase 1) Length = 864 Score = 56.2 bits (134), Expect = 8e-08 Identities = 34/94 (36%), Positives = 47/94 (50%), Gaps = 2/94 (2%) Frame = -2 Query: 648 WMAPE-LLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WM PE L G + K D +SFG+ LWEI + G PY ++ +V P Sbjct: 689 WMPPEAFLEGI---FTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPP 745 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 P +RI M QCW P++RPSF + +RL+ Sbjct: 746 RGCPGPVYRI-MTQCWQHEPELRPSFASILERLQ 778
>FLK_RAT (P09760) Tyrosine-protein kinase FLK (EC 2.7.10.2) (Fragment)| Length = 323 Score = 56.2 bits (134), Expect = 8e-08 Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PY M V R P Sbjct: 227 WTAPEALN--YGRYSSESDVWSFGILLWETFSLGVCPYPGM-TNQQAREQVERGYRMSAP 283 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 + C E +M +CW P+ RP F+++ L A+ Sbjct: 284 QNCPEEIFTIMMKCWDYKPENRPKFSDLHKELTAI 318
>EPHB3_HUMAN (P54753) Ephrin type-B receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HEK-2) Length = 998 Score = 56.2 bits (134), Expect = 8e-08 Identities = 29/92 (31%), Positives = 50/92 (54%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY +M +I + + PP P Sbjct: 804 WTAPEAI--AYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPP-P 860 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C LM CW + ++RP F+++ + L Sbjct: 861 MDCPTALHQLMLDCWVRDRNLRPKFSQIVNTL 892
>KIT_CHICK (Q08156) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 960 Score = 56.2 bits (134), Expect = 8e-08 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 1/105 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + + DV+S+GI LWE+ + G PY M + ++ R P Sbjct: 820 WMAPESI--FNCVYTFESDVWSYGILLWELFSLGSSPYPGMPVDSKFYKMIKEGYRMFSP 877 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQA 337 E PE +M+ CW A+P RP+F ++ + + RV A Sbjct: 878 ECSPPEMYDIMKSCWDADPLQRPTFKQIVQLIEQQLSDNAPRVYA 922
>BLK_MOUSE (P16277) Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte| kinase) (p55-BLK) Length = 498 Score = 56.2 bits (134), Expect = 8e-08 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE ++ + K DV+SFG+ L I+T G PY M +I + + R P P Sbjct: 394 WTAPEAIHFGVFTI--KADVWSFGVLLMVIVTYGRVPYPGMSNPEVIRSL-EHGYRMPCP 450 Query: 471 ETCDPE-WRILMEQCWSANPDIRPSF 397 ETC PE + ++ +CW P+ RP+F Sbjct: 451 ETCPPELYNDIITECWRGRPEERPTF 476
>EPHB3_CHICK (Q07498) Ephrin type-B receptor 3 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor CEK10) (Fragment) Length = 988 Score = 55.8 bits (133), Expect = 1e-07 Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY +M +I + + PP P Sbjct: 794 WTAPEAI--AYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPP-P 850 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C LM CW + ++RP F ++ + L Sbjct: 851 MDCPTALHQLMLDCWVRDRNLRPKFAQIVNTL 882
>SRC_RSVSE (P63185) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 55.8 bits (133), Expect = 1e-07 Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E+ T G PY M G ++ V R P P Sbjct: 427 WTAPEA--ALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDR-VERGYRMPCP 483 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 C LM QCW +P+ RP+F Sbjct: 484 PECPESLHDLMSQCWRRDPEERPTF 508
>RON_MOUSE (Q62190) Macrophage-stimulating protein receptor precursor (EC| 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating prote Length = 1378 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/99 (35%), Positives = 52/99 (52%), Gaps = 1/99 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + R + K DV+SFG+ LWE+LT G PY ++ + + R P P Sbjct: 1230 WMALESLQ--TYRFTTKSDVWSFGVLLWELLTRGAPPYPHID-PFDLSHFLAQGRRLPQP 1286 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 E C +M +CW A+P RP+F + ++ + A L Sbjct: 1287 EYCPDSLYHVMLRCWEADPAARPTFRALVLEVKQVVASL 1325
>EPB1B_XENLA (Q91736) Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein| kinase receptor XELK) (Fragment) Length = 902 Score = 55.8 bits (133), Expect = 1e-07 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 708 WTAPEAIR--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLPP-P 764 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP F E+ + L M Sbjct: 765 MDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKM 799
>EPHB4_MOUSE (P54761) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK-1) Length = 987 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + D +S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 786 WTAPEAI--AFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 843 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 + C LM CW + + RP F +V L M Sbjct: 844 D-CPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
>EPHB4_HUMAN (P54760) Ephrin type-B receptor 4 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor HTK) Length = 987 Score = 55.8 bits (133), Expect = 1e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + D +S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 786 WTAPEAI--AFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 843 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 + C LM CW + + RP F +V L M Sbjct: 844 D-CPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
>VGFR2_COTJA (P52583) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1) Length = 1348 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + DV+SFG+ LWEI + G PY + + R P Sbjct: 1064 WMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1121 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 + PE M CW +P RP+F+E+ + L +LQ+ V+ G Sbjct: 1122 DYTTPEMYQTMLDCWHGDPKQRPTFSELVEHL---GNLLQANVRQDG 1165
>ROS_CHICK (P08941) Proto-oncogene tyrosine-protein kinase ROS precursor (EC| 2.7.10.1) (c-ros-1) Length = 2311 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 2/94 (2%) Frame = -2 Query: 648 WMAPE-LLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L++G + S DV++FG+ +WE LT G++PY + ++ + + R Sbjct: 2144 WMAPESLIDGVFTNHS---DVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGG-RLES 2199 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 P C + R LM +CW+ +P RP+F + +L+ Sbjct: 2200 PNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQ 2233
>PTK6_MOUSE (Q64434) Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related| intestinal kinase) Length = 451 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/96 (37%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L S S K DV+SFG+ L EI + G+ PY M V+ R P P Sbjct: 353 WTAPEAL--SRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLR-VDAGYRMPCP 409 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMS 364 C P LM CWS +P RP F ++ ++L ++ Sbjct: 410 LECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGIT 445
>EPHB5_CHICK (Q07497) Ephrin type-B receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase CEK9) Length = 1002 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 808 WTAPEAVQ--YRKFTSSSDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIDQDYRLPPPP 865 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 + C +LM CW + RP F ++ L M Sbjct: 866 D-CPTVLHLLMLDCWQKDRVQRPKFEQIVSALDKM 899
>CSK_CHICK (P41239) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + S K DV+SFGI LWEI + G PY + ++ + P P Sbjct: 352 WTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDP-P 408 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 + C +M++CW+ +P RPSF ++ ++L Sbjct: 409 DGCPAIVYEVMKKCWTLDPGHRPSFHQLREQL 440
>UFO_HUMAN (P30530) Tyrosine-protein kinase receptor UFO precursor (EC| 2.7.10.1) (AXL oncogene) Length = 887 Score = 55.5 bits (132), Expect = 1e-07 Identities = 36/93 (38%), Positives = 49/93 (52%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 W+A E L + RV + K DV+SFG+ +WEI T G+ PY + I + + R Sbjct: 708 WIAIESL---ADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGN-RLKQ 763 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C LM +CW NP RPSFTE+ + L Sbjct: 764 PADCLDGLYALMSRCWELNPQDRPSFTELREDL 796
>FGFR3_MOUSE (Q61851) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) Length = 801 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 3/94 (3%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT--GEEPYANMHCGAIIGGIVNNSLRPP 478 WMAPE L RV + + DV+SFG+ LWEI T G PY + + ++ R Sbjct: 654 WMAPEAL---FDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIPVEELFK-LLKEGHRMD 709 Query: 477 VPETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P +C + ++M +CW A P RP+F ++ + L Sbjct: 710 KPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDL 743
>VGFR2_HUMAN (P35968) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen) Length = 1356 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + DV+SFG+ LWEI + G PY + + R P Sbjct: 1071 WMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAP 1128 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 + PE M CW P RP+F+E+ + L +LQ+ Q G Sbjct: 1129 DYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL---GNLLQANAQQDG 1172
>RET_HUMAN (P07949) Proto-oncogene tyrosine-protein kinase receptor ret| precursor (EC 2.7.10.1) (C-ret) Length = 1114 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/95 (35%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + DV+SFG+ LWEI+T G PY + + ++ R P Sbjct: 917 WMAIESL--FDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFN-LLKTGHRMERP 973 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 + C E LM QCW PD RP F +++ L M Sbjct: 974 DNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM 1008
>TNK1_MOUSE (Q99ML2) Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2)| (Kinase of embryonic stem cells) Length = 666 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTG-EEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + S DV+ FG+ LWE+ +G EEP+A + I+ + + R P P Sbjct: 289 WCAPESLRQGA--FSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKP 346 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 C L +CW+ +P RPSF+ + L+ Sbjct: 347 PLCSRALYSLALRCWAPHPADRPSFSNLEGLLQ 379
>ROS_AVISU (P00529) Tyrosine-protein kinase transforming protein ros (EC| 2.7.10.1) Length = 402 Score = 55.5 bits (132), Expect = 1e-07 Identities = 32/94 (34%), Positives = 54/94 (57%), Gaps = 2/94 (2%) Frame = -2 Query: 648 WMAPE-LLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L++G + S DV++FG+ +WE LT G++PY + ++ + + R Sbjct: 281 WMAPESLIDGVFTNHS---DVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGG-RLES 336 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 P C + R LM +CW+ +P RP+F + +L+ Sbjct: 337 PNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQ 370
>EPHA8_MOUSE (O09127) Ephrin type-A receptor 8 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) Length = 1004 Score = 55.5 bits (132), Expect = 1e-07 Identities = 35/95 (36%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + S DV+SFG+ +WE+L GE PY NM +I V R P P Sbjct: 803 WTAPEAI--AFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISS-VEEGYRLPAP 859 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + RP F V L A+ Sbjct: 860 MGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLDAL 894
>HTK16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.10.2)| Length = 757 Score = 55.5 bits (132), Expect = 1e-07 Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + S K DV+S+GI LWE+ T G+ PY M ++ + + R P Sbjct: 652 WYAPESINYGT--FSTKSDVWSYGITLWEMFTFGDLPYGEMTGNEVVS-FLEHCGRLEKP 708 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 + C +M CW +P+ RP+F E+ Sbjct: 709 DECPIHTYSIMLSCWHIDPNKRPTFNEL 736
>FGFR3_HUMAN (P22607) Fibroblast growth factor receptor 3 precursor (EC| 2.7.10.1) (FGFR-3) (CD333 antigen) Length = 806 Score = 55.5 bits (132), Expect = 1e-07 Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFG+ LWEI T G PY + + ++ R Sbjct: 660 WMAPEAL---FDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDK 715 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C + ++M +CW A P RP+F ++ + L Sbjct: 716 PANCTHDLYMIMRECWHAAPSQRPTFKQLVEDL 748
>CEK2_CHICK (P18460) Tyrosine kinase receptor CEK2 precursor (EC 2.7.10.1)| Length = 806 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFG+ LWEI T G PY + + ++ R Sbjct: 654 WMAPEAL---FDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDK 709 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAM 358 P C + ++M +CW A P RP+F ++ + L + M Sbjct: 710 PANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLTM 748
>CEK3_CHICK (P18461) Tyrosine kinase receptor CEK3 precursor (EC 2.7.10.1)| Length = 823 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFG+ +WEI T G PY + + ++ R Sbjct: 671 WMAPEAL---FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDK 726 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C E ++M CW A P RP+F ++ + L Sbjct: 727 PANCTNELYMMMRDCWQAVPSQRPTFKQLVEDL 759
>PR2_DROME (Q9I7F7) Tyrosine-protein kinase PR2 (EC 2.7.10.2)| Length = 1337 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/96 (35%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGI-VNNSLRPPV 475 W APE +N R + DV++FG+ LWE+ + G +P+A + I+ I N R Sbjct: 306 WCAPECIN--YLRFTNASDVWAFGVCLWEMFSYGFQPWAALTGLQILEAIDAPNYQRLEQ 363 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 P+ C E+ LM +CW + RP F E+ D+L M Sbjct: 364 PDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDM 399
>SRK1_SPOLA (P42686) Tyrosine-protein kinase isoform SRK1 (EC 2.7.10.2)| Length = 505 Score = 55.1 bits (131), Expect = 2e-07 Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +R + K DV+SFG+ L+EI+T G PY M ++ I N R P P Sbjct: 401 WTAPEA--AMYNRFTIKSDVWSFGVVLYEIITYGRFPYPGMTNPEVLEKIQQN-YRMPCP 457 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 C ++ +M CW +P RP+F Sbjct: 458 ANCPKQFHDIMLDCWREDPASRPTF 482
>PTK6_HUMAN (Q13882) Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor| kinase) (Tyrosine-protein kinase BRK) Length = 451 Score = 55.1 bits (131), Expect = 2e-07 Identities = 37/98 (37%), Positives = 51/98 (52%), Gaps = 2/98 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANM-HCGAIIGGIVNNSLRPPV 475 W APE L S S K DV+SFGI L E+ + G+ PY M + A + V+ R P Sbjct: 353 WTAPEAL--SRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLR--VDAGYRMPC 408 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSA 361 P C P LM CW +P+ RP F + +RL + ++ Sbjct: 409 PLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTS 446
>EPHB1_CHICK (Q07494) Ephrin type-B receptor 1 (EC 2.7.10.1) (Tyrosine-protein| kinase receptor EPH-2) (Tyrosine kinase CEK6 receptor) (Fragment) Length = 984 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 790 WTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPP-P 846 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP E+ + L M Sbjct: 847 MDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKM 881
>EPHA3_MOUSE (P29319) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ETK1) (MEK4) Length = 983 Score = 55.1 bits (131), Expect = 2e-07 Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 1/108 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W +PE + S + + DV+S+GI LWE+++ GE PY+ M +I V+ R P P Sbjct: 790 WTSPEAM--SYRKFTSASDVWSYGIVLWEVMSYGERPYSQMSNQDVIKA-VDERYRLPPP 846 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPGS 328 C LM CW + + RP F ++ ++L ++ PGS Sbjct: 847 MDCPAALYQLMLDCWQKDRNNRPKFEQIV-------SILDKLIRNPGS 887
>MOS_CHICK (P10741) Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte| maturation factor mos) Length = 349 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/102 (34%), Positives = 53/102 (51%), Gaps = 6/102 (5%) Frame = -2 Query: 642 APELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPETC 463 APELL G RV+ K D++SF I LW+I+ E+PY ++ +V +LRPP+ Sbjct: 251 APELLKGE--RVTAKADIYSFAITLWQIVMREQPYLGER-QYVLYAVVAYNLRPPLAAAI 307 Query: 462 DPE------WRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 E R ++ CW A+ + R S ++ LRA+ L Sbjct: 308 FHESAVGQRLRSIISCCWKADVEERLSAAQLLPSLRALKENL 349
>MUSK_HUMAN (O15146) Muscle, skeletal receptor tyrosine protein kinase precursor| (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK) Length = 869 Score = 55.1 bits (131), Expect = 2e-07 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 1/103 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM PE + +R + + DV+++G+ LWEI + G +PY M +I + + ++ P Sbjct: 768 WMPPESI--FYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILS-CP 824 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRV 343 E C E LM CWS P RPSFT + L M + V Sbjct: 825 ENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTV 867
>FER_HUMAN (P16591) Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2)| (p94-FER) (c-FER) Length = 822 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/99 (35%), Positives = 46/99 (46%), Gaps = 1/99 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE LN R S + DV+SFGI LWE + G PY M V R P Sbjct: 726 WTAPEALN--YGRYSSESDVWSFGILLWETFSLGVCPYPGM-TNQQAREQVERGYRMSAP 782 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAML 355 + C + +M +CW P+ RP F+E+ L + L Sbjct: 783 QHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKL 821
>MOS_XENLA (P12965) Serine/threonine-protein kinase mos (EC 2.7.11.1)| (pp39-mos) Length = 359 Score = 54.7 bits (130), Expect = 2e-07 Identities = 35/101 (34%), Positives = 55/101 (54%), Gaps = 6/101 (5%) Frame = -2 Query: 642 APELLNGSSSRVSEKVDVFSFGIALWEILTGEEPY-ANMHCGAIIGGIVNNSLRPPV-PE 469 APELL G V+ K D++SF I LW++++ E PY + C ++ +V LRP + P Sbjct: 241 APELLKGEP--VTAKADIYSFAITLWQMVSRELPYTGDRQC--VLYAVVAYDLRPEMGPL 296 Query: 468 TCDPE----WRILMEQCWSANPDIRPSFTEVTDRLRAMSAM 358 E R +++ CW+A P RP+ ++ +RL AM Sbjct: 297 FSHTEEGRAARTIVQSCWAARPQERPNAEQLLERLEQECAM 337
>FGFR2_XENLA (Q03364) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) Length = 813 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFG+ +WEI T G PY + + ++ R Sbjct: 659 WMAPEAL---FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDK 714 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C E ++M CW A P RP+F ++ + L Sbjct: 715 PANCTNELYMMMRDCWHAIPSHRPTFKQLVEDL 747
>ILK_MOUSE (O55222) Integrin-linked protein kinase (EC 2.7.11.1)| Length = 452 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEK-VDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVP 472 W+APE L + + D++SF + LWE++T E P+A++ I + LRP VP Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTVP 414 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 P LM+ C + +P RP F + L M Sbjct: 415 PGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKM 449
>JAK3_RAT (Q63272) Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3)| (JAK-3) Length = 1100 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 18/112 (16%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGA------IIGG------ 505 W APE L S + S + DV+SFG+ L+E+ T Y++ C +IG Sbjct: 989 WYAPESL--SDNIFSRQSDVWSFGVVLYELFT----YSDKSCSPSTEFLRMIGPEREGSP 1042 Query: 504 ------IVNNSLRPPVPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 ++ R P P TC E + LM+ CWS NP RP+F ++ +L A+ Sbjct: 1043 LCHLLELLAEGRRLPPPSTCPTEVQELMQLCWSPNPQDRPAFDTLSPQLDAL 1094 Score = 34.7 bits (78), Expect = 0.25 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 2/102 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGG--IVNNSLRPPV 475 W+APE L + + ++ + D + FG WE+ +G A MH ++ + R + Sbjct: 686 WVAPECLQEAGT-LNLEADKWGFGATTWEVFSG----APMHITSLEPAKKLKFYEDRGQL 740 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQS 349 P E L+ QC + +P RPSF + LR ++ ++ S Sbjct: 741 PALKWTELEGLIAQCMAYDPGRRPSFRAI---LRDLNGLITS 779
>LIMK1_MOUSE (P53668) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1)| Length = 647 Score = 54.7 bits (130), Expect = 2e-07 Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 5/107 (4%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEIL---TGEEPY--ANMHCGAIIGGIVNNSLR 484 WMAPE++NG S EKVDVFSFGI L EI+ + Y M G + G ++ Sbjct: 515 WMAPEMINGRS--YDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY-- 570 Query: 483 PPVPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRV 343 P C P + + +C +P+ RPSF ++ L + L + Sbjct: 571 --CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLSGHL 615
>CSK_RAT (P32577) Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase)| Length = 450 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/92 (33%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + S K DV+SFGI LWEI + G PY + ++ V + P Sbjct: 352 WTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPR-VEKGYKMDAP 408 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 + C P +M+ CW + RP+F ++ ++L Sbjct: 409 DGCPPAVYDVMKNCWHLDAATRPTFLQLREQL 440
>EPHA3_BRARE (O13146) Ephrin type-A receptor 3 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor ZEK1) (EPH-like kinase 1) Length = 981 Score = 54.7 bits (130), Expect = 2e-07 Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY M +I V+ R P P Sbjct: 795 WTAPEAI--TYRKFTSASDVWSYGIVMWEVISYGERPYWEMSNQDVIKA-VDEGYRLPAP 851 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C LM CW N RP F ++ + L Sbjct: 852 MDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTL 883
>FGFR2_MOUSE (P21803) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) Length = 821 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFG+ +WEI T G PY + + ++ R Sbjct: 669 WMAPEAL---FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDK 724 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C E ++M CW A P RP+F ++ + L Sbjct: 725 PTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 757
>FGFR2_HUMAN (P21802) Fibroblast growth factor receptor 2 precursor (EC| 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen) Length = 821 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/93 (35%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SFG+ +WEI T G PY + + ++ R Sbjct: 669 WMAPEAL---FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFK-LLKEGHRMDK 724 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C E ++M CW A P RP+F ++ + L Sbjct: 725 PANCTNELYMMMRDCWHAVPSQRPTFKQLVEDL 757
>FLT3_HUMAN (P36888) FL cytokine receptor precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen) Length = 993 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE L + K DV+S+GI LWEI + G PY + A ++ N + P Sbjct: 854 WMAPESLFEGIYTI--KSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQP 911 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E I+M+ CW+ + RPSF +T L Sbjct: 912 FYATEEIYIIMQSCWAFDSRKRPSFPNLTSFL 943
>BCK1_YEAST (Q01389) Serine/threonine-protein kinase BCK1/SLK1/SSP31 (EC| 2.7.11.1) Length = 1478 Score = 54.7 bits (130), Expect = 2e-07 Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 12/131 (9%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVPE 469 WMAPE+++ + S KVD++S G + E+ G+ P++N+ A + I + PP+PE Sbjct: 1345 WMAPEMVD-TKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPE 1403 Query: 468 TCDP----EWRILMEQCWSANPDIRPS--------FTEVTDRLRAMSAMLQSRVQAPGS* 325 P R ++ C+ NP+ RP+ F+EV + S L ++ Sbjct: 1404 DTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIK----- 1458 Query: 324 *SLDVINQQKI 292 S D +N K+ Sbjct: 1459 -SNDKLNSSKL 1468
>FYN_XIPHE (P27446) Proto-oncogene tyrosine-protein kinase FYN (EC 2.7.10.2)| (P59-FYN) Length = 536 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/85 (38%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E++T G PY M+ ++ V R P P Sbjct: 431 WTAPEA--ALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQ-VERGYRMPCP 487 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 + C LM QCW +P+ RP+F Sbjct: 488 QDCPASLHELMLQCWKKDPEERPTF 512
>YES_XIPHE (P27447) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 543 Score = 54.7 bits (130), Expect = 2e-07 Identities = 33/85 (38%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E++T G PY M ++ V+ R P P Sbjct: 438 WTAPEA--ALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQ-VDRGYRMPCP 494 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 + C +M QCW PD RP+F Sbjct: 495 QGCPESLHEMMRQCWKKEPDERPTF 519
>ILK1_HUMAN (Q13418) Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59| kDa serine/threonine-protein kinase) (p59ILK) Length = 452 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEK-VDVFSFGIALWEILTGEEPYANMHCGAIIGGIVNNSLRPPVP 472 W+APE L + + D++SF + LWE++T E P+A++ I + LRP +P Sbjct: 355 WVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIP 414 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 P LM+ C + +P RP F + L M Sbjct: 415 PGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKM 449
>SRK3_SPOLA (P42689) Tyrosine-protein kinase SRK3 (EC 2.7.10.2) (Fragment)| Length = 334 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/93 (37%), Positives = 51/93 (54%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +R + K DV+SFG+ + EI+T G PY M ++ V+ R P P Sbjct: 228 WTAPEA--ALYNRFTIKSDVWSFGVLISEIVTHGRMPYPGMTNRQVLEA-VDRGYRMPCP 284 Query: 471 ETC-DPEWRILMEQCWSANPDIRPSFTEVTDRL 376 E C DP ++I++ CW PD RP+F + + L Sbjct: 285 EGCPDPLYKIMLS-CWKHEPDDRPTFESLKNLL 316
>LIMK1_RAT (P53669) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 54.3 bits (129), Expect = 3e-07 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEIL---TGEEPY--ANMHCGAIIGGIVNNSLR 484 WMAPE++NG S EKVDVFSFGI L EI+ + Y M G + G ++ Sbjct: 515 WMAPEMINGRS--YDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY-- 570 Query: 483 PPVPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 P C P + + +C +P+ RPSF ++ L + Sbjct: 571 --CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607
>SRC_RSVSA (P00524) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E+ T G PY M G ++ V R P P Sbjct: 427 WTAPEA--ALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDR-VERGYRMPCP 483 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 C LM QCW +P+ RP+F Sbjct: 484 PECPESLHDLMCQCWRRDPEERPTF 508
>SRC_AVISR (P00525) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 525 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E+ T G PY M G ++ V R P P Sbjct: 427 WTAPEA--ALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDR-VERGYRMPCP 483 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 C LM QCW +P+ RP+F Sbjct: 484 PECPESLHDLMCQCWRRDPEERPTF 508
>ITK_HUMAN (Q08881) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT) Length = 620 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W +PE+ S SR S K DV+SFG+ +WE+ + G+ PY N ++ I + R P Sbjct: 524 WASPEVF--SFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDI-STGFRLYKP 580 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 +M CW P+ RP+F+ + +L Sbjct: 581 RLASTHVYQIMNHCWKERPEDRPAFSRLLRQL 612
>EPHB2_HUMAN (P29323) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen) Length = 1055 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 792 WTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP-P 848 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP F ++ + L M Sbjct: 849 MDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883
>ITK_MOUSE (Q03526) Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2)| (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) Length = 625 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W +PE+ S SR S K DV+SFG+ +WE+ + G+ PY N ++ I + R P Sbjct: 529 WASPEVF--SFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDI-STGFRLYKP 585 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 +M CW P+ RP F+++ +L Sbjct: 586 RLASCHVYQIMNHCWKEKPEDRPPFSQLLSQL 617
>SEA_AVIET (P23049) Tyrosine-protein kinase transforming protein SEA (EC| 2.7.10.2) Length = 370 Score = 54.3 bits (129), Expect = 3e-07 Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ +WE+LT G PY + + ++ R P P Sbjct: 231 WMALESLQ--TQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGR-RLPQP 287 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQ 352 + C +M CW+ P+ RPSF+ + L + A L+ Sbjct: 288 QPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERVLASLE 327
>SRK4_SPOLA (P42690) Tyrosine-protein kinase isoform SRK4 (EC 2.7.10.2)| Length = 506 Score = 54.3 bits (129), Expect = 3e-07 Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE SR + K DV+SFGI L+E++T G PY M ++ I S R P P Sbjct: 401 WTAPEA--AMYSRFTIKSDVWSFGIVLYEVITYGRFPYPGMTNAQVLEQI-QQSYRMPRP 457 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C + +M CW +P RP+F ++ +L Sbjct: 458 MGCPEKLYAIMMDCWREDPASRPTFETLSWQL 489
>MET_MOUSE (P16056) Hepatocyte growth factor receptor precursor (EC 2.7.10.1)| (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) Length = 1379 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/95 (33%), Positives = 53/95 (55%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L + + + K DV+SFG+ LWE++T G PY +++ I ++ R P Sbjct: 1247 WMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGR-RLLQP 1303 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C +M +CW ++RPSF+E+ R+ ++ Sbjct: 1304 EYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSI 1338
>LTK_MOUSE (P08923) Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1)| Length = 888 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM PE L + K D +SFG+ LWEI + G PY ++ I + P Sbjct: 685 WMPPEAL--LEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDPPR 742 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLR 373 P +RI M QCW P++RP F + +R++ Sbjct: 743 NCPGPVYRI-MTQCWQHQPELRPDFGSILERIQ 774
>PGFRA_MOUSE (P26618) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1089 Score = 54.3 bits (129), Expect = 3e-07 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 1/90 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + DV+S+GI LWEI + G PY M + + + R P Sbjct: 861 WMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKP 918 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTD 382 + E +M QCW++ P+ RPSF +++ Sbjct: 919 DHATSEVYEIMVQCWNSEPEKRPSFYHLSE 948
>EPHB2_MOUSE (P54763) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3) Length = 994 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 800 WTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP-P 856 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP F ++ + L M Sbjct: 857 MDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 891
>FGFR1_RAT (Q04589) Basic fibroblast growth factor receptor 1 precursor (EC| 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) Length = 822 Score = 53.9 bits (128), Expect = 4e-07 Identities = 33/103 (32%), Positives = 53/103 (51%), Gaps = 2/103 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L R+ + + DV+SFG+ LWEI T G P + + ++ R Sbjct: 666 WMAPEAL---FDRIYTHQSDVWSFGVLLWEIFTLGGSPNPGVPVEELFK-LLKEGHRMDK 721 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSR 346 P C E ++M CW+A P RP+F ++ + L + A+ ++ Sbjct: 722 PSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRIVALTSNQ 764
>SRC_RSVPA (P31693) Tyrosine-protein kinase transforming protein Src (EC| 2.7.10.2) (p60-Src) (v-Src) (pp60v-src) Length = 522 Score = 53.9 bits (128), Expect = 4e-07 Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E+ T G PY M G ++ V R P P Sbjct: 424 WTAPEA--ALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNGEVLDR-VERGYRMPCP 480 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 C LM QCW +P+ RP+F Sbjct: 481 PECPESLHDLMCQCWRKDPEERPTF 505
>LIMK1_HUMAN (P53667) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1)| Length = 647 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEIL---TGEEPY--ANMHCGAIIGGIVNNSLR 484 WMAPE++NG S EKVDVFSFGI L EI+ + Y M G + G ++ Sbjct: 515 WMAPEMINGRS--YDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRY-- 570 Query: 483 PPVPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 P C P + + +C +P+ RPSF ++ L + Sbjct: 571 --CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETL 607
>LIMK1_CHICK (Q8QFP8) LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (chLIMK1)| Length = 662 Score = 53.9 bits (128), Expect = 4e-07 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 3/105 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEIL---TGEEPYANMHCGAIIGGIVNNSLRPP 478 WMAPE++NG S EKVD+FSFGI L EI+ + + Y + G V L Sbjct: 522 WMAPEMINGRS--YDEKVDIFSFGIVLCEIIGRVSADPDY--LPRTTDFGLNVRGFLERY 577 Query: 477 VPETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRV 343 P C P + + C +P+ RPSF+++ L + L R+ Sbjct: 578 CPPACPPSFFPIAACCCDLDPEKRPSFSKLEQWLETLRMHLDIRL 622
>KIT_MOUSE (P05532) Mast/stem cell growth factor receptor precursor (EC| 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) Length = 975 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + S + + DV+S+GI LWE+ + G PY M + ++ R P Sbjct: 833 WMAPESI--FSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSP 890 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 E E +M+ CW A+P RP+F +V Sbjct: 891 EHAPAEMYDVMKTCWDADPLKRPTFKQV 918
>PGFRA_RAT (P20786) Alpha platelet-derived growth factor receptor precursor (EC| 2.7.10.1) (PDGF-R-alpha) Length = 1088 Score = 53.9 bits (128), Expect = 4e-07 Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 1/90 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + + DV+S+G+ LWEI + G PY M + + + R P Sbjct: 860 WMAPESI--FDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKP 917 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTD 382 + E +M QCW++ P+ RPSF +++ Sbjct: 918 DHATSEVYEIMVQCWNSEPEKRPSFYHLSE 947
>EPHB6_MOUSE (O08644) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) (MEP) Length = 1014 Score = 53.9 bits (128), Expect = 4e-07 Identities = 30/88 (34%), Positives = 45/88 (51%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE++ S DV+SFGI +WE+++ GE PY +M+ ++ I R P P Sbjct: 820 WAAPEVITHGKYTTSS--DVWSFGILMWEVMSYGERPYWDMNEQEVLNAI-EQEFRLPPP 876 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 C P +LM W + RP F ++ Sbjct: 877 PGCPPGLHLLMLDTWQKDRARRPHFDQL 904
>EPHB2_COTJA (Q90344) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor QEK5) Length = 987 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 793 WTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP-P 849 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP F ++ + L M Sbjct: 850 MDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 884
>EPHB2_CHICK (P28693) Ephrin type-B receptor 2 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK5) Length = 1004 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + DV+S+GI +WE+++ GE PY +M +I I + PP P Sbjct: 810 WTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPP-P 866 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP F ++ + L M Sbjct: 867 MDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 901
>EPB1A_XENLA (Q91571) Ephrin type-B receptor 1-A precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor XEK) Length = 985 Score = 53.9 bits (128), Expect = 4e-07 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W A E + + + + DV+S+GI +WE+++ GE PY M +I I + PP P Sbjct: 791 WTAQEAI--AYRKFTSASDVWSYGIVMWEVMSYGERPYWTMSNQDVINAIEQDYRLPP-P 847 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C LM CW + + RP E+ + LR M Sbjct: 848 MDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRPM 882
>FGFR4_MOUSE (Q03142) Fibroblast growth factor receptor 4 precursor (EC| 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) Length = 799 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 2/93 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRV-SEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WMAPE L RV + + DV+SF I LWEI T G PY + + ++ R Sbjct: 652 WMAPEAL---FDRVYTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFS-LLREGHRMER 707 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 P C E LM +CW A P RP+F ++ + L Sbjct: 708 PPNCPSELYGLMRECWHAAPSQRPTFKQLVEAL 740
>EPHA6_HUMAN (Q9UF33) Ephrin type-A receptor 6 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2) Length = 1035 Score = 53.5 bits (127), Expect = 5e-07 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + S D +S+GI +WE+++ GE PY M +I I R P P Sbjct: 841 WTAPEAI--AYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSI-EEGYRLPAP 897 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C LM CW + RP FT++ L Sbjct: 898 MGCPASLHQLMLHCWQKERNHRPKFTDIVSFL 929
>7LESS_DROME (P13368) Protein sevenless (EC 2.7.10.1)| Length = 2554 Score = 53.1 bits (126), Expect = 7e-07 Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 2/101 (1%) Frame = -2 Query: 648 WMAPE-LLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPV 475 WM+PE L++G + S DV++FG+ WEILT G++PYA + ++ + R Sbjct: 2393 WMSPESLVDGLFTTQS---DVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGG-RLQQ 2448 Query: 474 PETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQ 352 P C + L+ CW +P RPSF + L A+S L+ Sbjct: 2449 PPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLR 2489
>LCK_HUMAN (P06239) Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2)| (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell-specific protein-tyrosine kinase) Length = 508 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/85 (38%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE +N + + K DV+SFGI L EI+T G PY M +I + R P Sbjct: 405 WTAPEAINYGTFTI--KSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNL-ERGYRMVRP 461 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 + C E LM CW P+ RP+F Sbjct: 462 DNCPEELYQLMRLCWKERPEDRPTF 486
>YES_AVISY (P00527) Tyrosine-protein kinase transforming protein YES (EC| 2.7.10.2) (Fragment) Length = 528 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/85 (38%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E++T G PY M ++ V R P P Sbjct: 428 WTAPEA--ALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQ-VERGYRMPCP 484 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 + C LM+ CW +PD RP+F Sbjct: 485 QGCPESLHELMKLCWKKDPDERPTF 509
>ROR2_MOUSE (Q9Z138) Tyrosine-protein kinase transmembrane receptor ROR2| precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2) Length = 944 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM+PE + + S D++S+G+ LWE+ + G +PY ++ I + + P P Sbjct: 658 WMSPEAV--MYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRSRQVLP-CP 714 Query: 471 ETCDPEW-RILMEQCWSANPDIRPSFTEVTDRLRA 370 + C P W LM +CW+ P RP F ++ RLR+ Sbjct: 715 DDC-PAWVYALMIECWNEFPSRRPRFKDIHSRLRS 748
>YES_CHICK (P09324) Tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes)| Length = 540 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/85 (38%), Positives = 43/85 (50%), Gaps = 1/85 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE R + K DV+SFGI L E++T G PY M ++ V R P P Sbjct: 435 WTAPEA--ALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQ-VERGYRMPCP 491 Query: 471 ETCDPEWRILMEQCWSANPDIRPSF 397 + C LM+ CW +PD RP+F Sbjct: 492 QGCPESLHELMKLCWKKDPDERPTF 516
>TOR_DROME (P18475) Tyrosine-protein kinase receptor torso precursor (EC| 2.7.10.1) Length = 923 Score = 53.1 bits (126), Expect = 7e-07 Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W+A E L + + + DV+SFG+ L+EI T G PY ++ ++ ++ R P Sbjct: 785 WLALESL--THQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQ-LLRQGHRMKRP 841 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 E C E LME CWS+ P RP+F+ + RL M Sbjct: 842 EGCTQEMFSLMESCWSSVPSHRPTFSALKHRLGGM 876
>VGFR2_RAT (O08775) Vascular endothelial growth factor receptor 2 precursor (EC| 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) Length = 1343 Score = 53.1 bits (126), Expect = 7e-07 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 1/107 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMAPE + + V+SFG+ LWEI + G PY + + R P Sbjct: 1067 WMAPETIFDRIYTIQS--GVWSFGVLLWEIFSLGASPYPGVKIDEKFCRRLKEGTRMRAP 1124 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQAPG 331 + PE M CW +P+ RP+F+E+ + L +LQ+ Q G Sbjct: 1125 DYTTPEMYQTMLDCWHEDPNQRPAFSELVEHL---GNLLQANAQQDG 1168
>EPHA5_CHICK (P54755) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor CEK7) Length = 1013 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY M +I V R P P Sbjct: 820 WTAPEAI--AFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTNQDVIKA-VEEGYRLPSP 876 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C LM CW + + RP F E+ L Sbjct: 877 MDCPAALYQLMLDCWQKDRNSRPKFDEIVSML 908
>ABL_DROME (P00522) Tyrosine-protein kinase Abl (EC 2.7.10.2) (Abelson| protein) (D-ash) Length = 1620 Score = 53.1 bits (126), Expect = 7e-07 Identities = 34/95 (35%), Positives = 47/95 (49%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE L + ++ S K DV++FG+ LWEI T G PY + + + + R P Sbjct: 534 WTAPEGL--AYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKL-DKGYRMERP 590 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 C PE LM QCW + RP+F + L M Sbjct: 591 PGCPPEVYDLMRQCWQWDATDRPTFKSIHHALEHM 625
>EPHA5_MOUSE (Q60629) Ephrin type-A receptor 5 precursor (EC 2.7.10.1)| (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7) Length = 877 Score = 53.1 bits (126), Expect = 7e-07 Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY M +I V R P P Sbjct: 683 WTAPEAI--AFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKA-VEEGYRLPSP 739 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C LM CW + + RP F E+ + L Sbjct: 740 MDCPAALYQLMLDCWQKDRNSRPKFDEIVNML 771
>INSR_DROME (P09208) Insulin-like receptor precursor (EC 2.7.10.1) (DIR) (DInr)| (dIRH) [Contains: Insulin-like receptor alpha subunit; Insulin-like receptor beta 1 subunit; Insulin-like receptor beta 2 subunit] Length = 2144 Score = 53.1 bits (126), Expect = 7e-07 Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WM PE L S DVFSFG+ LWE+ T +PY + ++ +++ + P Sbjct: 1562 WMPPESLRDGV--YSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMER-P 1618 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 E C LM++CW RPSF ++ Sbjct: 1619 ENCPDFLHKLMQRCWHHRSSARPSFLDI 1646
>EGL15_CAEEL (Q10656) Myoblast growth factor receptor egl-15 precursor (EC| 2.7.10.1) (Egg-laying defective protein 15) Length = 1040 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/104 (32%), Positives = 47/104 (45%), Gaps = 1/104 (0%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 WMA E L+ + V DV+S+G+ LWEI+T G PY + + + P P Sbjct: 840 WMALEALDSNVYTVES--DVWSYGVLLWEIMTLGGTPYPTIAMPELYANLKEGYRMEP-P 896 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAMSAMLQSRVQ 340 C E LM CW + RPSF + D L M M ++ Sbjct: 897 HLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWMLTMTNETIE 940
>EPHB6_PANTR (P0C0K6) Ephrin type-B receptor 6 precursor (Tyrosine-protein| kinase-defective receptor EPH-6) Length = 1005 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/88 (34%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE++ S DV+SFGI +WE+++ GE PY +M ++ I R P P Sbjct: 811 WAAPEVIAHGKHTTSS--DVWSFGILMWEVMSYGERPYWDMSEQEVLNAI-EQEFRLPPP 867 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEV 388 C P +LM W + RP F ++ Sbjct: 868 PGCPPGLHLLMLDTWQKDRARRPHFDQL 895
>JAK2_RAT (Q62689) Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2)| (JAK-2) Length = 1132 Score = 52.8 bits (125), Expect = 9e-07 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 16/107 (14%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT----------------GEEPYANMHCGA 517 W APE L + S+ S DV+SFG+ L+E+ T G + M Sbjct: 1020 WYAPESL--TESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFH 1077 Query: 516 IIGGIVNNSLRPPVPETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 +I + NN R P PE C E ++M +CW+ N + RPSF +++ R+ Sbjct: 1078 LIELLKNNG-RLPRPEGCPDEIYVIMTECWNNNVNQRPSFRDLSLRV 1123 Score = 34.3 bits (77), Expect = 0.33 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 1/95 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W+ PE + + ++ D +SFG LWEI + G++P + + + + + P P Sbjct: 718 WVPPECIENPKN-LTLATDKWSFGTTLWEICSGGDKPLSALDSQRKL-QFYEDKHQLPAP 775 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRLRAM 367 + E L+ C PD RP+F V L ++ Sbjct: 776 KW--TELANLINTCMDYEPDFRPAFRAVIRDLNSL 808
>EPA4A_BRARE (O13148) Ephrin type-A receptor 4a (EC 2.7.10.1) (Tyrosine-protein| kinase receptor ZEK2) (EPH-like kinase 2) (Fragment) Length = 292 Score = 52.8 bits (125), Expect = 9e-07 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Frame = -2 Query: 648 WMAPELLNGSSSRVSEKVDVFSFGIALWEILT-GEEPYANMHCGAIIGGIVNNSLRPPVP 472 W APE + + + + DV+S+GI +WE+++ GE PY +M +I I PP P Sbjct: 173 WTAPEAI--TYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPP-P 229 Query: 471 ETCDPEWRILMEQCWSANPDIRPSFTEVTDRL 376 C LM CW RP F+++ + L Sbjct: 230 MDCPVSLHQLMLDCWQKERAERPKFSQIVNML 261 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 96,867,453 Number of Sequences: 219361 Number of extensions: 2063687 Number of successful extensions: 8051 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 6415 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7669 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6086476506 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
