ナショナルバイオリソースプロジェクト
-Barley Genetic Resources Database-
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| Clone Name | rbags39k17 |
|---|---|
| Clone Library Name | barley_pub |
>PET8_YEAST (P38921) Putative mitochondrial carrier protein PET8| Length = 284 Score = 78.2 bits (191), Expect = 2e-14 Identities = 47/154 (30%), Positives = 79/154 (51%), Gaps = 4/154 (2%) Frame = -3 Query: 668 LLQILQTDGFFGL----YAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGES 501 L IL+ D GL Y G++ T++R +P + + +EYLK + + P + Sbjct: 134 LQSILRNDNKEGLRKNLYRGWSTTIMREIPFTCIQFPLYEYLKKTWAKANGQSQVEPWKG 193 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 +CG++AG I+A TTPLD +KTRLM + + ++ + + EEG G+GPR Sbjct: 194 AICGSIAGGIAAATTTPLDFLKTRLMLN---KTTASLGSVIIRIYREEGPAVFFSGVGPR 250 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLESCERKA 219 + + AI +ET ++ KS+ + E +A Sbjct: 251 TMWISAGGAIFLGMYETVHSLLSKSFPTAGEMRA 284 Score = 36.6 bits (83), Expect = 0.070 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Frame = -3 Query: 503 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 S+L GA AG + + P+D +KTRL + G A G G+ RG+G Sbjct: 7 SLLSGAAAGTSTDLVFFPIDTIKTRLQAKGG-------------FFANGGYKGIYRGLGS 53 Query: 323 RVLHSACFAAIGYCAFE----TARLMILKSYLESCER 225 V+ SA A++ + +++ +R I K Y + E+ Sbjct: 54 AVVASAPGASLFFISYDYMKVKSRPYISKLYSQGSEQ 90 Score = 34.7 bits (78), Expect = 0.27 Identities = 40/175 (22%), Positives = 72/175 (41%), Gaps = 15/175 (8%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA------LSKSNAPNLTPGESVLCGAL 483 G+ G+Y G + ++ + P L + S++Y+K + L + L + + + Sbjct: 43 GYKGIYRGLGSAVVASAPGASLFFISYDYMKVKSRPYISKLYSQGSEQLIDTTTHMLSSS 102 Query: 482 AGAISAGLT-TPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLS----RGIGPRV 318 G I A L P +VVK R T+V + S T+Q ++ + GL RG + Sbjct: 103 IGEICACLVRVPAEVVKQR--TQVHSTNSSW--QTLQSILRNDNKEGLRKNLYRGWSTTI 158 Query: 317 LHSACFAAIGYCAFETARLMILK----SYLESCERKAADEMKTGVAAA*VCAIPF 165 + F I + +E + K S +E + + G+AAA + F Sbjct: 159 MREIPFTCIQFPLYEYLKKTWAKANGQSQVEPWKGAICGSIAGGIAAATTTPLDF 213
>YDE9_SCHPO (Q10442) Putative mitochondrial carrier C12B10.09| Length = 345 Score = 77.8 bits (190), Expect = 3e-14 Identities = 44/106 (41%), Positives = 67/106 (63%), Gaps = 1/106 (0%) Frame = -3 Query: 629 YAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGALAGAISAGLTT 453 YAGY T+ R +P ++ + +E+LK + + S NL E+ + G++AG I+A LTT Sbjct: 219 YAGYGITIAREIPFTLIQFPIWEHLKLKWRIKHSRNKNLAH-EAAISGSIAGGIAAALTT 277 Query: 452 PLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 P DVVKTR+MT +Q + V T++ ++A EG + L +GI PRVL Sbjct: 278 PFDVVKTRIMT---SQQRLSYVFTIKSIVAHEGFLALYKGIVPRVL 320 Score = 30.8 bits (68), Expect = 3.8 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 5/88 (5%) Frame = -3 Query: 488 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 AL I AGL P+D +KTRL + G + G G+ RG+G Sbjct: 85 ALGAGICAGLAVDLSLFPIDTLKTRLQAKGG-------------FVKNGGFHGVYRGLGS 131 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYL 240 ++ SA A++ + +E + + +S L Sbjct: 132 ILVGSAPGASLFFTTYENMKSRLSQSGL 159
>CMC2_HUMAN (Q9UJS0) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 675 Score = 75.9 bits (185), Expect = 1e-13 Identities = 42/122 (34%), Positives = 68/122 (55%), Gaps = 2/122 (1%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 L +++ GFFG+Y G A LR++P + + + ++KA ++ ++PG +L GA Sbjct: 471 LSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG--QVSPGSLLLAGA 528 Query: 485 LAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 +AG +A L TP DV+KTRL R G V+ ++++ EEG L +G G RV Sbjct: 529 IAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFR 588 Query: 311 SA 306 S+ Sbjct: 589 SS 590 Score = 45.4 bits (106), Expect = 2e-04 Identities = 33/124 (26%), Positives = 57/124 (45%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++L+ +GFFGLY G LL P + + ++++ + K + L +L G Sbjct: 380 KVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPL--AAEILAGGC 437 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AG T PL++VK RL +V + + + V+ + G G+ +G L Sbjct: 438 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIP 495 Query: 302 FAAI 291 F+AI Sbjct: 496 FSAI 499 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 G++AGA+ A P+D+VKTR+ + VG + ++V+ EG GL RG+ Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394 Query: 329 GPRVLHSACFAAI 291 P++L A AI Sbjct: 395 LPQLLGVAPEKAI 407
>DIF1_CAEEL (Q27257) Protein dif-1| Length = 312 Score = 75.1 bits (183), Expect = 2e-13 Identities = 43/126 (34%), Positives = 68/126 (53%), Gaps = 5/126 (3%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++ + G +Y G ATLLR++PA S +EYLK + L+PG +++ G L Sbjct: 155 KLYKQGGISSIYRGTGATLLRDIPASAAYLSVYEYLKKKFSGEGAQRTLSPGATLMAGGL 214 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL---- 315 AG + G+ P DV+K+RL T + + G ++EV+ EEG L +G P +L Sbjct: 215 AGIANWGVCIPADVLKSRLQTAPEGKYPDGIRGVLREVLREEGPRALFKGFWPVMLRAFP 274 Query: 314 -HSACF 300 ++ACF Sbjct: 275 ANAACF 280 Score = 32.0 bits (71), Expect = 1.7 Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 5/130 (3%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAIS 468 +GFF LY G AA L+ P + + K + + +T ++ GALAG + Sbjct: 60 EGFFALYKGMAAPLVGVSPLFAVFFGGCAVGK-WLQQTDPSQEMTFIQNANAGALAGVFT 118 Query: 467 AGLTTPLDVVKTRL-MTRVGAQGSRT----VVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 + P + +K L + + G+ GS + ++++ + G+ + RG G +L Sbjct: 119 TIVMVPGERIKCLLQVQQAGSAGSGVHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIP 178 Query: 302 FAAIGYCAFE 273 +A +E Sbjct: 179 ASAAYLSVYE 188
>CMC2_MOUSE (Q9QXX4) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 676 Score = 74.3 bits (181), Expect = 3e-13 Identities = 41/122 (33%), Positives = 67/122 (54%), Gaps = 2/122 (1%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 L +++ GFFG+Y G A LR++P + + + ++KA ++ ++PG +L GA Sbjct: 472 LSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG--QVSPGSLLLAGA 529 Query: 485 LAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 +AG +A L TP DV+KTRL R G V ++++ EEG L +G+ RV Sbjct: 530 IAGMPAASLVTPADVIKTRLQVAARAGQTTYNGVTDCFRKILREEGPKALWKGVAARVFR 589 Query: 311 SA 306 S+ Sbjct: 590 SS 591 Score = 43.5 bits (101), Expect = 6e-04 Identities = 32/124 (25%), Positives = 56/124 (45%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++L+ +GFFGLY G LL P + + ++++ + K + L + G Sbjct: 381 KVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLL--AEIFAGGC 438 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AG T PL++VK RL +V + + + V+ + G G+ +G L Sbjct: 439 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIP 496 Query: 302 FAAI 291 F+AI Sbjct: 497 FSAI 500 Score = 40.0 bits (92), Expect = 0.006 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 G++AGA+ A P+D+VKTR+ + VG + ++V+ EG GL RG+ Sbjct: 336 GSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395 Query: 329 GPRVLHSACFAAI 291 P++L A AI Sbjct: 396 LPQLLGVAPEKAI 408
>MRS4_YEAST (P23500) Mitochondrial RNA-splicing protein MRS4| Length = 304 Score = 71.6 bits (174), Expect = 2e-12 Identities = 51/150 (34%), Positives = 71/150 (47%), Gaps = 11/150 (7%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 QI Q +GF Y Y TL N+P ++ +E F + N+ N P LCG + Sbjct: 162 QIYQNEGFAAFYYSYPTTLAMNIPFAAFNFMIYESASKF-FNPQNSYN--PLIHCLCGGI 218 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTV----------VGTMQEVIAE-EGLMGLSR 336 +GA A LTTPLD +KT L R GS TV G I E G G R Sbjct: 219 SGATCAALTTPLDCIKTVLQVR----GSETVSIEIMKDANTFGRASRAILEVHGWKGFWR 274 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMILKS 246 G+ PR++ + AI + A+E A+ ++K+ Sbjct: 275 GLKPRIVANIPATAISWTAYECAKHFLMKN 304 Score = 35.4 bits (80), Expect = 0.16 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 +L GA AG + L P+D +KTR+ + S ++ + ++ EG M L +G+ Sbjct: 27 LLAGAFAGIMEHSLMFPIDALKTRVQAAGLNKAASTGMISQISKISTMEGSMALWKGVQS 86 Query: 323 RVL-----HSACFAAIGYC 282 +L H+ F +C Sbjct: 87 VILGAGPAHAVYFGTYEFC 105
>PET8_ASHGO (O60029) Putative mitochondrial carrier protein PET8| Length = 271 Score = 71.6 bits (174), Expect = 2e-12 Identities = 40/121 (33%), Positives = 65/121 (53%) Frame = -3 Query: 635 GLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLT 456 GLY G+ T++R +P + + +EYLK + + ++ + +CG+LAG I+A T Sbjct: 148 GLYRGWWTTIMREIPFTCIQFPLYEYLKKKWAAYAEIERVSAWQGAVCGSLAGGIAAAAT 207 Query: 455 TPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 276 TPLDV+KTR+M + ++ + + EEG RGIGPR + + AI + Sbjct: 208 TPLDVLKTRMMLH---ERRVPMLHLARTLFREEGARVFFRGIGPRTMWISAGGAIFLGVY 264 Query: 275 E 273 E Sbjct: 265 E 265 Score = 32.0 bits (71), Expect = 1.7 Identities = 21/80 (26%), Positives = 38/80 (47%) Frame = -3 Query: 503 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 S++ GA AG + + P+D +KTRL + G G G+ RG+G Sbjct: 8 SLVSGAAAGTSTDVVFFPIDTLKTRLQAKGG-------------FFHNGGYRGIYRGLGS 54 Query: 323 RVLHSACFAAIGYCAFETAR 264 V+ SA A++ + +++ + Sbjct: 55 AVVASAPGASLFFVTYDSMK 74
>GDC_MOUSE (Q8C0K5) Grave disease carrier protein homolog (GDC) (Mitochondrial| solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 69.7 bits (169), Expect = 7e-12 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 2/137 (1%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L + Q +G+ GLY G A ++R P G + + +FE+ K F +K ++ G Sbjct: 80 LRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHV--HRLMAG 137 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRV-GAQGSRTVVGTMQEVIAEE-GLMGLSRGIGPRVL 315 ++AG + T PLDVV+ RL +V G ++ + + A+E G +G RG+ P +L Sbjct: 138 SMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMPTIL 197 Query: 314 HSACFAAIGYCAFETAR 264 A +A + + F T + Sbjct: 198 GMAPYAGVSFFTFGTLK 214 Score = 51.6 bits (122), Expect = 2e-06 Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 18/142 (12%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 501 GF G Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 184 GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALLGRPSSDNPNVLVLKTHIN 243 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGA-----QGSRTVVGTMQEVIAEEGL-MGLS 339 +LCG +AGAI+ ++ P DV + R+ ++GA + T+ TM+ V + G+ GL Sbjct: 244 LLCGGVAGAIAQTISYPFDVTRRRM--QLGAVLPEFEKCLTMRETMKYVYGQHGIRRGLY 301 Query: 338 RGIGPRVLHSACFAAIGYCAFE 273 RG+ + A+ + +E Sbjct: 302 RGLSLNYIRCIPSQAVAFTTYE 323 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/83 (31%), Positives = 39/83 (46%) Frame = -3 Query: 503 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 S L G +AG + PLD VK L V+ T++ V +EG +GL +G G Sbjct: 39 SFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGNGA 98 Query: 323 RVLHSACFAAIGYCAFETARLMI 255 ++ + AI + AFE + I Sbjct: 99 MMIRIFPYGAIQFMAFEHYKTFI 121
>CMC1_CAEEL (Q21153) Probable calcium-binding mitochondrial carrier K02F3.2| Length = 707 Score = 68.2 bits (165), Expect = 2e-11 Identities = 48/155 (30%), Positives = 75/155 (48%), Gaps = 2/155 (1%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 +L+ GF GLY G A LR++P + + ++ + K A + + N +PG +A Sbjct: 514 VLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAHAK-LASADEDGMN-SPGTLFASAFIA 571 Query: 479 GAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 G +AGL TP DV+KTRL R G V+ +++I EEG M L +G RV S+ Sbjct: 572 GVPAAGLVTPADVIKTRLQVAARAGQTTYNGVIDCARKLIKEEGPMSLWKGTAARVCRSS 631 Query: 305 CFAAIGYCAFETARLMILKSYLESCERKAADEMKT 201 A+ +E + + + S R E+ T Sbjct: 632 PQFAVTLLTYEVLQRLFYVDFAGS--RPTGSELAT 664 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/134 (26%), Positives = 60/134 (44%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++++ +G GLY G ++ P + + +Y++ P GE ++ G Sbjct: 421 KVVKFEGLLGLYRGLLPQIVGVAPEKAIKLTMNDYMRDKFTKDGKIPLY--GE-IIAGGT 477 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 G T PL++VK RL T Q + +G V+ E G +GL +G L Sbjct: 478 GGMCQVVFTNPLEIVKIRLQTAGEVQQAGKKIGVF-TVLKELGFLGLYKGSRACFLRDIP 536 Query: 302 FAAIGYCAFETARL 261 F+AI + A+ A+L Sbjct: 537 FSAIYFPAYAHAKL 550 Score = 42.0 bits (97), Expect = 0.002 Identities = 26/75 (34%), Positives = 42/75 (56%), Gaps = 6/75 (8%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSR 336 L G++AGA A P+D+VKTR+ + VG + + ++V+ EGL+GL R Sbjct: 374 LLGSVAGACGATAVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLYR 433 Query: 335 GIGPRVLHSACFAAI 291 G+ P+++ A AI Sbjct: 434 GLLPQIVGVAPEKAI 448
>CMC2_MACFA (Q8HXW2) Calcium-binding mitochondrial carrier protein Aralar2| (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin) Length = 674 Score = 67.4 bits (163), Expect = 4e-11 Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 2/122 (1%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 L +++ GFFG+Y G A LR++P + + + + +A ++ ++PG +L GA Sbjct: 471 LSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHARASFANEDG--QVSPGSLLLAGA 528 Query: 485 LAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 +AG +A L TP DV+KTRL R G V+ ++++ EEG L +G RV Sbjct: 529 IAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFKKILREEGPKALWKG-AARVFR 587 Query: 311 SA 306 S+ Sbjct: 588 SS 589 Score = 47.8 bits (112), Expect = 3e-05 Identities = 35/133 (26%), Positives = 61/133 (45%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++L+ +GFFGLY G LL P + + ++++ + K + L +L G Sbjct: 380 KVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPL--AAEILAGGC 437 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AG T PL++VK RL +V + + + V+ + G G+ +G L Sbjct: 438 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIP 495 Query: 302 FAAIGYCAFETAR 264 F+AI + + AR Sbjct: 496 FSAIYFPCYAHAR 508 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 G++AGA+ A P+D+VKTR+ + VG + ++V+ EG GL RG+ Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394 Query: 329 GPRVLHSACFAAI 291 P++L A AI Sbjct: 395 LPQLLGVAPEKAI 407
>GDC_RAT (P16261) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) (Fragment) Length = 322 Score = 67.0 bits (162), Expect = 5e-11 Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 5/140 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L + Q +G+ GLY G A ++R P G + + +FE+ K F +K ++ G Sbjct: 80 LRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHV--HRLMAG 137 Query: 488 ALAGAISAG---LTTPLDVVKTRLMTRV-GAQGSRTVVGTMQEVIAEE-GLMGLSRGIGP 324 ++AG +S T PLDVV+ RL +V G ++ + + A+E G +G RG+ P Sbjct: 138 SMAGKMSMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMP 197 Query: 323 RVLHSACFAAIGYCAFETAR 264 +L A +A++ + F T + Sbjct: 198 TILGMAPYASVSFFTFGTLK 217 Score = 45.4 bits (106), Expect = 2e-04 Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 18/123 (14%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 501 GF G Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 187 GFLGFYRGLMPTILGMAPYASVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHIN 246 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGA-----QGSRTVVGTMQEVIAEEGL-MGLS 339 +LCG +A AI+ ++ P DV + R+ ++GA + T+ TM+ V G+ GL Sbjct: 247 LLCGGVARAIAQTISYPFDVTRRRM--QLGAVLPEFEKCLTMRETMKYVYGHHGIRRGLY 304 Query: 338 RGI 330 RG+ Sbjct: 305 RGL 307 Score = 39.7 bits (91), Expect = 0.008 Identities = 25/83 (30%), Positives = 39/83 (46%) Frame = -3 Query: 503 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 S L G++AG + PLD VK L V+ ++ V +EG +GL +G G Sbjct: 39 SFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVLSPLRAVPQKEGYLGLYKGNGA 98 Query: 323 RVLHSACFAAIGYCAFETARLMI 255 ++ + AI + AFE + I Sbjct: 99 MMIRIFPYGAIQFMAFEHYKTFI 121
>GDC_BOVIN (Q01888) Grave disease carrier protein (GDC) (Mitochondrial solute| carrier protein homolog) (Solute carrier family 25 member 16) Length = 330 Score = 66.2 bits (160), Expect = 8e-11 Identities = 38/137 (27%), Positives = 71/137 (51%), Gaps = 2/137 (1%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L + + +G+ GLY G A ++R P G + + +FE+ K +K ++ G Sbjct: 78 LRAVPKKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGVSGHV--HRLMAG 135 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-VVGTMQEVIAEE-GLMGLSRGIGPRVL 315 ++AG + T PLD+V+ RL +V + + T ++ + + A+E G +G RG+ P +L Sbjct: 136 SMAGMTAVICTYPLDMVRVRLAFQVKGEHTYTGIIHAFKTIYAKEGGFLGFYRGLMPTIL 195 Query: 314 HSACFAAIGYCAFETAR 264 A +A + + F T + Sbjct: 196 GMAPYAGVSFFTFGTLK 212 Score = 51.2 bits (121), Expect = 3e-06 Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 18/142 (12%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 501 GF G Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 182 GFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHIN 241 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGA-----QGSRTVVGTMQEVIAEEGL-MGLS 339 +LCG +AGAI+ ++ P DV + R+ ++GA + T+ TM+ V G+ GL Sbjct: 242 LLCGGVAGAIAQTISYPFDVTRRRM--QLGAVLPEFEKCLTMRETMKYVYGHHGIRKGLY 299 Query: 338 RGIGPRVLHSACFAAIGYCAFE 273 RG+ + A+ + +E Sbjct: 300 RGLSLNYIRCVPSQAVAFTTYE 321 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/83 (31%), Positives = 39/83 (46%) Frame = -3 Query: 503 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 S L G +AG + PLD VK L V T++ V +EG +GL +G G Sbjct: 37 SFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYRHLGVFSTLRAVPKKEGYLGLYKGNGA 96 Query: 323 RVLHSACFAAIGYCAFETARLMI 255 ++ + AI + AFE + +I Sbjct: 97 MMIRIFPYGAIQFMAFEHYKTLI 119
>GDC_HUMAN (P16260) Grave disease carrier protein (GDC) (Grave disease| autoantigen) (GDA) (Mitochondrial solute carrier protein homolog) (Solute carrier family 25 member 16) Length = 332 Score = 66.2 bits (160), Expect = 8e-11 Identities = 39/137 (28%), Positives = 69/137 (50%), Gaps = 2/137 (1%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L + Q +GF GLY G A ++R P G + + +FE+ K +K ++ G Sbjct: 80 LRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHV--HRLMAG 137 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-VVGTMQEVIAEE-GLMGLSRGIGPRVL 315 ++AG + T P+D+V+ RL +V + T ++ + + A+E G G RG+ P +L Sbjct: 138 SMAGMTAVICTDPVDMVRVRLAFQVKGEHRYTGIIHAFKTIYAKEGGFFGFYRGLMPTIL 197 Query: 314 HSACFAAIGYCAFETAR 264 A +A + + F T + Sbjct: 198 GMAPYAGVSFFTFGTLK 214 Score = 46.6 bits (109), Expect = 7e-05 Identities = 39/140 (27%), Positives = 62/140 (44%), Gaps = 16/140 (11%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS---------KSNAPN---LTPGES 501 GFFG Y G T+L P +S+ +F LK+ LS S+ PN L + Sbjct: 184 GFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGSPSSDNPNVLVLKTHVN 243 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRV---GAQGSRTVVGTMQEVIAEEGL-MGLSRG 333 +LCG +A AI+ ++ P DV + R+ + T+ TM+ G+ GL RG Sbjct: 244 LLCGGVARAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYDYGHHGIRKGLYRG 303 Query: 332 IGPRVLHSACFAAIGYCAFE 273 + + A+ + +E Sbjct: 304 LSLNYIRCIPSQAVAFTTYE 323 Score = 40.4 bits (93), Expect = 0.005 Identities = 25/83 (30%), Positives = 39/83 (46%) Frame = -3 Query: 503 SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 S L G++AG + PLD VK L V ++ V +EG +GL +G G Sbjct: 39 SFLAGSIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGA 98 Query: 323 RVLHSACFAAIGYCAFETARLMI 255 ++ + AI + AFE + +I Sbjct: 99 MMIRIFPYGAIQFMAFEHYKTLI 121
>GHC2_RAT (Q505J6) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 65.9 bits (159), Expect = 1e-10 Identities = 40/119 (33%), Positives = 62/119 (52%), Gaps = 3/119 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++L+T G GLY G ATLLR++P ++ + F L +S+ + S + G Sbjct: 172 ELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTG-KASFTHSFVAGCA 230 Query: 482 AGAISAGLTTPLDVVKTRLMT---RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 AG++SA TPLDV+KTR+ T +G R V +++ +EG +G G R L Sbjct: 231 AGSVSAVAVTPLDVLKTRIQTLKKGLGEDTYRGVTDCARKLWTQEGAAAFMKGAGCRAL 289 Score = 43.9 bits (102), Expect = 4e-04 Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 24/155 (15%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++ + +GF G+Y G A L P + ++ ++L+ + NL +L G Sbjct: 52 LVKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLK--MEMLAG 109 Query: 488 ALAGAISAGLTTPLDVVKTRLM----TRVGAQGSRTVVGTMQ------------------ 375 AG +T P++++K +L V Q S + T + Sbjct: 110 CGAGICQVVITCPMEMLKIQLQDAGRLAVCQQASASATPTSRPYSTGSTSTHRRPSATLI 169 Query: 374 --EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 276 E++ +GL GL RG+G +L F+ I + F Sbjct: 170 AWELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLF 204 Score = 37.4 bits (85), Expect = 0.041 Identities = 26/120 (21%), Positives = 53/120 (44%) Frame = -3 Query: 530 NAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGL 351 ++ +L+ ++ G +AG + P+D+ KTRL + G + + + + EG Sbjct: 2 SSQDLSITAKLINGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYKGMTDCLVKTARAEGF 61 Query: 350 MGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAAA*VCAI 171 +G+ RG + AI A + R ++++ + +R EM G A +C + Sbjct: 62 LGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQ---DGTQRNLKMEMLAGCGAG-ICQV 117
>YM39_YEAST (Q03829) Putative mitochondrial carrier YMR166C| Length = 368 Score = 65.5 bits (158), Expect = 1e-10 Identities = 42/147 (28%), Positives = 77/147 (52%), Gaps = 24/147 (16%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK--AFALSKSNAPN--LTPGESVLC 492 +++ +GF L+ GY ATL R+LP L ++ +E + AF + + + + L+ +L Sbjct: 203 VIKEEGFRSLFFGYKATLARDLPFSALQFAFYEKFRQLAFKIEQKDGRDGELSIPNEILT 262 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRV--------------------GAQGSRTVVGTMQE 372 GA AG ++ +TTP+DVVKTR+ T+ A S ++ +++ Sbjct: 263 GACAGGLAGIITTPMDVVKTRVQTQQPPSQSNKSYSVTHPHVTNGRPAALSNSISLSLRT 322 Query: 371 VIAEEGLMGLSRGIGPRVLHSACFAAI 291 V EG++G G+GPR + ++ ++I Sbjct: 323 VYQSEGVLGFFSGVGPRFVWTSVQSSI 349 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 8/137 (5%) Frame = -3 Query: 635 GLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLT 456 GLY GY A +L + P+ + + ++EY K + + S G L IS+ + Sbjct: 109 GLYGGYMAAMLGSFPSAAIFFGTYEYTKRTMIEDWQINDTITHLS--AGFLGDFISSFVY 166 Query: 455 TPLDVVKTRLMTR--------VGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 P +V+KTRL + + ++ VI EEG L G + F Sbjct: 167 VPSEVLKTRLQLQGRFNNPFFQSGYNYSNLRNAIKTVIKEEGFRSLFFGYKATLARDLPF 226 Query: 299 AAIGYCAFETARLMILK 249 +A+ + +E R + K Sbjct: 227 SALQFAFYEKFRQLAFK 243 Score = 32.3 bits (72), Expect = 1.3 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGL-MGLSRGIGP 324 V+ G + G I LD VKTR + R ++ + + EEG+ GL G Sbjct: 57 VVSGGIGGKIGDSAMHSLDTVKTRQQGAPNVKKYRNMISAYRTIWLEEGVRRGLYGGYMA 116 Query: 323 RVLHSACFAAIGYCAFE-TARLMI 255 +L S AAI + +E T R MI Sbjct: 117 AMLGSFPSAAIFFGTYEYTKRTMI 140
>AGC1_YEAST (Q12482) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 902 Score = 65.5 bits (158), Expect = 1e-10 Identities = 47/154 (30%), Positives = 74/154 (48%), Gaps = 7/154 (4%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALS-----KSNAPNLTPGESV 498 QI++ G GLY G AA L+R++P + + ++ +LK K+ L E + Sbjct: 672 QIVKKLGLRGLYNGVAACLMRDVPFSAIYFPTYAHLKKDLFDFDPNDKTKRNRLKTWELL 731 Query: 497 LCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 GA+AG +A LTTP DV+KTRL R G + ++ ++ EE +G G Sbjct: 732 TAGAIAGMPAAFLTTPFDVIKTRLQIDPRKGETKYNGIFHAIRTILKEESFRSFFKGGGA 791 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYLESCERK 222 RVL S+ A+E + K ++ S + K Sbjct: 792 RVLRSSPQFGFTLAAYE-----LFKGFIPSPDNK 820 Score = 53.9 bits (128), Expect = 4e-07 Identities = 35/128 (27%), Positives = 62/128 (48%), Gaps = 2/128 (1%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 LL+I+ +G GLY+G L+ P + + ++++ K+ +L P ++ G Sbjct: 574 LLKIISREGIKGLYSGLGPQLIGVAPEKAIKLTVNDFMRNRLTDKNGKLSLFP--EIISG 631 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 A AGA T PL++VK RL + G + T +++ + GL GL G+ ++ Sbjct: 632 ASAGACQVIFTNPLEIVKIRLQVQSDYVGENIQQANETATQIVKKLGLRGLYNGVAACLM 691 Query: 314 HSACFAAI 291 F+AI Sbjct: 692 RDVPFSAI 699 Score = 45.1 bits (105), Expect = 2e-04 Identities = 21/67 (31%), Positives = 39/67 (58%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 G++AG I A + P+D +KTR+ + + + + ++I+ EG+ GL G+GP+++ Sbjct: 537 GSIAGCIGATVVYPIDFIKTRMQAQRSLAQYKNSIDCLLKIISREGIKGLYSGLGPQLIG 596 Query: 311 SACFAAI 291 A AI Sbjct: 597 VAPEKAI 603
>CMC1_DROME (Q9VA73) Calcium-binding mitochondrial carrier Aralar1| Length = 695 Score = 65.1 bits (157), Expect = 2e-10 Identities = 41/116 (35%), Positives = 59/116 (50%), Gaps = 3/116 (2%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 G FGLY G A LLR++P + + ++ + KA K + P + GA+AG +A Sbjct: 491 GLFGLYKGARACLLRDVPFSAIYFPTYAHTKAMMADKDGYNH--PLTLLAAGAIAGVPAA 548 Query: 464 GLTTPLDVVKTRLMTRVGAQGSRTVVG---TMQEVIAEEGLMGLSRGIGPRVLHSA 306 L TP DV+KTRL V G T G ++++AEEG +G RV S+ Sbjct: 549 SLVTPADVIKTRLQV-VARSGQTTYTGVWDATKKIMAEEGPRAFWKGTAARVFRSS 603 Score = 49.3 bits (116), Expect = 1e-05 Identities = 38/137 (27%), Positives = 61/137 (44%), Gaps = 1/137 (0%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++++ +GF GLY G L+ P + + + ++ K N+ VL G Sbjct: 393 KVVRHEGFMGLYRGLLPQLMGVAPEKAIKLTVNDLVRDKLTDKKG--NIPTWAEVLAGGC 450 Query: 482 AGAISAGLTTPLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 AGA T PL++VK RL A GS+ V+ E GL GL +G +L Sbjct: 451 AGASQVVFTNPLEIVKIRLQVAGEIASGSKI---RAWSVVRELGLFGLYKGARACLLRDV 507 Query: 305 CFAAIGYCAFETARLMI 255 F+AI + + + M+ Sbjct: 508 PFSAIYFPTYAHTKAMM 524 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/72 (34%), Positives = 40/72 (55%), Gaps = 5/72 (6%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTR-----VGAQGSRTVVGTMQEVIAEEGLMGLSRGIG 327 G+ AGA+ A + P+D+VKTR+ + +G R ++V+ EG MGL RG+ Sbjct: 349 GSFAGAVGATVVYPIDLVKTRMQNQRAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLL 408 Query: 326 PRVLHSACFAAI 291 P+++ A AI Sbjct: 409 PQLMGVAPEKAI 420
>MFRN2_BRARE (Q7T292) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) Length = 376 Score = 64.3 bits (155), Expect = 3e-10 Identities = 44/146 (30%), Positives = 68/146 (46%), Gaps = 9/146 (6%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + Q +G Y Y L N+P L + ++EYL+ + + P ++ GALA Sbjct: 220 VWQREGALAFYRSYTTQLTMNVPFQALHFMTYEYLQELLNPQRH---YNPSSHMVSGALA 276 Query: 479 GAISAGLTTPLDVVKTRLMTRVG------AQGSRTVVG---TMQEVIAEEGLMGLSRGIG 327 GAI+A TTPLDV KT L T+ ++ R + G + V GL +G+ Sbjct: 277 GAIAAAATTPLDVCKTLLNTQESLAVDSVSRSGRHITGLGHAFRTVYRLGGLPAYFKGVQ 336 Query: 326 PRVLHSACFAAIGYCAFETARLMILK 249 RV++ AI + +E + MI K Sbjct: 337 ARVIYQMPSTAISWSVYEFFKYMITK 362 Score = 33.1 bits (74), Expect = 0.78 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 6/106 (5%) Frame = -3 Query: 554 KAFALSKSNAPNLTPGES----VLCGALAGAISAGLTTPLDVVKTRL--MTRVGAQGSRT 393 +A LS+ + L G S +L GA+AG + L P+D VKTR+ + A R Sbjct: 59 EASDLSEPDYEGLPQGASTSTHMLAGAVAGIMEHCLMFPIDCVKTRMQSLQPEPAARYRN 118 Query: 392 VVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 V+ + ++ EG+ RG+ + + A+ + +E + ++ Sbjct: 119 VMDALWRIMRTEGIWRPIRGLNITAVGAGPAHALYFACYERLKKVL 164
>MFRN2_MOUSE (Q8R0Z5) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) Length = 364 Score = 64.3 bits (155), Expect = 3e-10 Identities = 41/144 (28%), Positives = 65/144 (45%), Gaps = 7/144 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + Q +G Y Y L N+P + + ++E+L+ + P VLCGA A Sbjct: 215 VWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRR---YNPSSHVLCGACA 271 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-------TMQEVIAEEGLMGLSRGIGPR 321 GA++A TTPLDV KT L T+ + + G + V G+ RG+ R Sbjct: 272 GAVAAAATTPLDVCKTLLNTQESLALNSNITGHITGMASAFRTVYQVGGVTAYFRGVQAR 331 Query: 320 VLHSACFAAIGYCAFETARLMILK 249 V++ AI + +E + +I K Sbjct: 332 VIYQIPSTAIAWSVYEFFKYLITK 355 Score = 30.4 bits (67), Expect = 5.0 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 10/77 (12%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTMQEVIAEEGLMGLSRGI- 330 ++ GA+AG + + P+D VKTR+ + A R V+ + ++ EGL RG+ Sbjct: 76 MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIMRTEGLWRPMRGLN 135 Query: 329 ------GP-RVLHSACF 300 GP L+ AC+ Sbjct: 136 VTATGAGPAHALYFACY 152
>MFRN_DROME (Q9VAY3) Mitoferrin| Length = 379 Score = 63.5 bits (153), Expect = 5e-10 Identities = 47/159 (29%), Positives = 78/159 (49%), Gaps = 1/159 (0%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN-LTPGESVLCGAL 483 I + +GF Y Y L+ NLP + ++++E+ + +K N P + GA Sbjct: 152 IYKREGFKAFYRAYGTQLVMNLPYQTIHFTTYEFFQ----NKMNLERKYNPPVHMAAGAA 207 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AGA +A +TTPLDV+KT L T+ +R ++ +++ G +G RG RVL+S Sbjct: 208 AGACAAAVTTPLDVIKTLLNTQETGL-TRGMIEASRKIYHMAGPLGFFRGTTARVLYSMP 266 Query: 302 FAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAAA 186 AI + +E K YL + AD+ K+ + + Sbjct: 267 ATAICWSTYE-----FFKFYLCGLD---ADQYKSSITGS 297 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/92 (28%), Positives = 47/92 (51%) Frame = -3 Query: 524 PNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMG 345 P + G ++ GA+AG + + PLD VKTR+ + + +V T++ +I EGL+ Sbjct: 10 PTTSVGVNMTAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKNMNIVSTLRTMITREGLLR 69 Query: 344 LSRGIGPRVLHSACFAAIGYCAFETARLMILK 249 RG VL + ++ + A+E + + K Sbjct: 70 PIRGASAVVLGAGPAHSLYFAAYEMTKELTAK 101 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/132 (23%), Positives = 60/132 (45%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L ++ +G G +A +L PA L ++++E K ++ NL V+ G Sbjct: 58 LRTMITREGLLRPIRGASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRNLN---YVISG 114 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 A+A I +++P DV+K R+ S VV ++++ EG R G +++ + Sbjct: 115 AVATLIHDAISSPTDVIKQRMQMYNSPYTS--VVSCVRDIYKREGFKAFYRAYGTQLVMN 172 Query: 308 ACFAAIGYCAFE 273 + I + +E Sbjct: 173 LPYQTIHFTTYE 184
>GHC2_MOUSE (Q9DB41) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) (Fragment) Length = 312 Score = 63.5 bits (153), Expect = 5e-10 Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 3/119 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++L+T G GLY G ATLLR++P ++ + F L +S+ + S + G Sbjct: 169 ELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTG-KASFTHSFVAGCT 227 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGT---MQEVIAEEGLMGLSRGIGPRVL 315 AG+++A TPLDV+KTR+ T G T G +++ +EG +G G R L Sbjct: 228 AGSVAAVAVTPLDVLKTRIQTLKKGLGEDTYSGVTDCARKLWTQEGPAAFMKGAGCRAL 286 Score = 43.9 bits (102), Expect = 4e-04 Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 24/155 (15%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++ + +GF G+Y G A L P + ++ ++L+ + NL +L G Sbjct: 49 LMKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLK--MEMLAG 106 Query: 488 ALAGAISAGLTTPLDVVKTRLM----TRVGAQGSRTVVGT-------------------- 381 AG +T P++++K +L V Q S + T Sbjct: 107 CGAGICQVVITCPMEMLKIQLQDAGRLAVCHQASASATPTSRPYSTGSTSTHRRPSATLI 166 Query: 380 MQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 276 +E++ +GL GL RG+G +L F+ I + F Sbjct: 167 ARELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLF 201 Score = 39.7 bits (91), Expect = 0.008 Identities = 26/110 (23%), Positives = 48/110 (43%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 ++ G +AG + P+D+ KTRL + G R + + + EG +G+ RG Sbjct: 9 IINGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYRGMTDCLMKTARAEGFLGMYRGAAVN 68 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAAA*VCAI 171 + AI A + R ++++ + +R EM G A +C + Sbjct: 69 LTLVTPEKAIKLAANDFLRQLLMQ---DGTQRNLKMEMLAGCGAG-ICQV 114
>BT1_MAIZE (P29518) Protein brittle-1, chloroplast precursor| Length = 436 Score = 63.5 bits (153), Expect = 5e-10 Identities = 39/133 (29%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL-CGAL 483 I+Q +G+ GL+ G A +LR P+ + + +++ K F K + P P + L GAL Sbjct: 179 IMQNEGWTGLFRGNAVNVLRVAPSKAIEHFTYDTAKKFLTPKGDEPPKIPIPTPLVAGAL 238 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AG S T P++++KTR+ + V +++ +EG L RG+ P ++ Sbjct: 239 AGFASTLCTYPMELIKTRVTIEKDVYDN--VAHAFVKILRDEGPSELYRGLTPSLIGVVP 296 Query: 302 FAAIGYCAFETAR 264 +AA + A+ET + Sbjct: 297 YAACNFYAYETLK 309 Score = 61.6 bits (148), Expect = 2e-09 Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 7/156 (4%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF---ALSKSNAPNLTPGESVL 495 ++IL+ +G LY G +L+ +P ++ ++E LK A + ++ P ++L Sbjct: 272 VKILRDEGPSELYRGLTPSLIGVVPYAACNFYAYETLKRLYRRATGRRPGADVGPVATLL 331 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQE----VIAEEGLMGLSRGIG 327 G+ AGAI++ T PL+V + ++ +VGA G R V + ++ +EG GL RG+G Sbjct: 332 IGSAAGAIASSATFPLEVARKQM--QVGAVGGRQVYQNVLHAIYCILKKEGAGGLYRGLG 389 Query: 326 PRVLHSACFAAIGYCAFETARLMILKSYLESCERKA 219 P + A I + +E + +++ E E +A Sbjct: 390 PSCIKLMPAAGIAFMCYEACKKILVDKEDEEEEDEA 425 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/79 (36%), Positives = 45/79 (56%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 ++ GA+AGA+S PL+ ++T LM VG+ G ++ G Q ++ EG GL RG Sbjct: 138 LVSGAIAGAVSRTFVAPLETIRTHLM--VGSIGVDSMAGVFQWIMQNEGWTGLFRGNAVN 195 Query: 320 VLHSACFAAIGYCAFETAR 264 VL A AI + ++TA+ Sbjct: 196 VLRVAPSKAIEHFTYDTAK 214
>CMC1_MOUSE (Q8BH59) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 677 Score = 63.2 bits (152), Expect = 7e-10 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL-CG 489 L +LQ G FGLY G A LR++P + + + + K ++ G ++L G Sbjct: 469 LNVLQDLGLFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGRVG---GINLLTAG 525 Query: 488 ALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 ALAG +A L TP DV+KTRL R G VV ++++ EEG +G RV Sbjct: 526 ALAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVVDCFRKILREEGPSAFWKGTAARVF 585 Query: 314 HSA 306 S+ Sbjct: 586 RSS 588 Score = 48.1 bits (113), Expect = 2e-05 Identities = 36/136 (26%), Positives = 65/136 (47%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++L+ +GFFGLY G L+ P + + ++++ +K + P E +L G Sbjct: 378 KVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRD-KFTKRDGSIPLPAE-ILAGGC 435 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AG T PL++VK RL +V + + + V+ + GL GL +G L Sbjct: 436 AGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALNVLQDLGLFGLYKGAKACFLRDIP 493 Query: 302 FAAIGYCAFETARLMI 255 F+AI + + +L++ Sbjct: 494 FSAIYFPVYAHCKLLL 509 Score = 41.2 bits (95), Expect = 0.003 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 9/76 (11%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---------QEVIAEEGLMGLS 339 G++AGA+ A P+D+VKTR+ + +G+ +VVG + ++V+ EG GL Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQ---RGTGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389 Query: 338 RGIGPRVLHSACFAAI 291 RG+ P+++ A AI Sbjct: 390 RGLIPQLIGVAPEKAI 405
>MCAT_ARATH (Q93XM7) Mitochondrial carnitine/acylcarnitine carrier-like protein| (Protein A BOUT DE SOUFFLE) (Carnitine/acylcarnitine translocase-like protein) (CAC-like protein) Length = 300 Score = 62.4 bits (150), Expect = 1e-09 Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 G GL+ G T R +P ++++E K F S+ +L G ++ G +AGA Sbjct: 169 GARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAGGSDTSSLGQGSLIMAGGVAGASFW 228 Query: 464 GLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVLHSACFAA 294 G+ P DVVK+ L +V + G+M ++++ EG+ GL +G GP + S A Sbjct: 229 GIVYPTDVVKSVL--QVDDYKNPRYTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANA 286 Query: 293 IGYCAFETAR 264 + A+E R Sbjct: 287 ACFLAYEMTR 296 Score = 30.4 bits (67), Expect = 5.0 Identities = 11/38 (28%), Positives = 24/38 (63%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA 549 +IL+++G GLY G+ + R++PA + ++E ++ Sbjct: 260 KILKSEGVKGLYKGFGPAMARSVPANAACFLAYEMTRS 297
>UCP5_MOUSE (Q9Z2B2) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 62.4 bits (150), Expect = 1e-09 Identities = 35/141 (24%), Positives = 70/141 (49%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I + +G LY+G A LLR G + ++ LK + + L +++CG Sbjct: 91 LFRIYKEEGILALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICG 148 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 ++G IS+ + P DV+K R+ + G+ +++G+ ++ +EG GL RG+ P + Sbjct: 149 VVSGVISSTIANPTDVLKIRMQAQ-GSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207 Query: 308 ACFAAIGYCAFETARLMILKS 246 A + ++ + ++ S Sbjct: 208 AIVVGVELPVYDITKKHLIVS 228 Score = 34.3 bits (77), Expect = 0.35 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLM-------TRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 333 G LA ++ T P+D+ KTRL R R + + + EEG++ L G Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDVRFKEIKYRGMFHALFRIYKEEGILALYSG 106 Query: 332 IGPRVLHSACFAAIGYCAFETARLMILK 249 I P +L A + I +++ + + ++ Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLFVE 134 Score = 32.3 bits (72), Expect = 1.3 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 6/137 (4%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN--LTPGESVLC 492 + I Q +G GL+ G T R + ++ K + + LT S Sbjct: 185 IDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLIVSGMLGDTILTHFVSSFT 244 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV-GTMQEVI---AEEGLMGLSRGIGP 324 LAGA+++ P+DVV+TR+M + G + GT+ ++ EG L +G P Sbjct: 245 CGLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTLDGILKMWKHEGFFALYKGFWP 301 Query: 323 RVLHSACFAAIGYCAFE 273 L + I + +E Sbjct: 302 NWLRLGPWNIIFFITYE 318 Score = 29.6 bits (65), Expect = 8.6 Identities = 13/39 (33%), Positives = 24/39 (61%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 552 +L++ + +GFF LY G+ LR P ++ + ++E LK Sbjct: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
>MRS3_YEAST (P10566) Mitochondrial RNA-splicing protein MRS3| Length = 314 Score = 62.4 bits (150), Expect = 1e-09 Identities = 46/148 (31%), Positives = 70/148 (47%), Gaps = 11/148 (7%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 QI Q++G Y Y TL+ N+P ++ +E F L+ SN N P LCG++ Sbjct: 172 QIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYESSTKF-LNPSNEYN--PLIHCLCGSI 228 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTV-----------VGTMQEVIAEEGLMGLSR 336 +G+ A +TTPLD +KT L R GS+TV + G G R Sbjct: 229 SGSTCAAITTPLDCIKTVLQIR----GSQTVSLEIMRKADTFSKAASAIYQVYGWKGFWR 284 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMIL 252 G PR++ + AI + A+E A+ ++ Sbjct: 285 GWKPRIVANMPATAISWTAYECAKHFLM 312 Score = 47.4 bits (111), Expect = 4e-05 Identities = 30/131 (22%), Positives = 58/131 (44%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I ++G L+ G + +L PA + + ++E+ K + S+ P ++ + GA A Sbjct: 81 ISTSEGTLALWKGVQSVILGAGPAHAVYFGTYEFCKKNLIDSSDTQTHHPFKTAISGACA 140 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 S L P D +K R+ A +V T +++ EGL ++ + F Sbjct: 141 TTASDALMNPFDTIKQRIQLNTSA----SVWQTTKQIYQSEGLAAFYYSYPTTLVMNIPF 196 Query: 299 AAIGYCAFETA 267 AA + +E++ Sbjct: 197 AAFNFVIYESS 207 Score = 37.7 bits (86), Expect = 0.031 Identities = 21/106 (19%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMT-RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGP 324 ++ GA AG + + P+D +KTR+ + + ++ ++ + + EG + L +G+ Sbjct: 37 LIAGAFAGIMEHSVMFPIDALKTRIQSANAKSLSAKNMLSQISHISTSEGTLALWKGVQS 96 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAAA 186 +L + A+ + +E + K+ ++S + + KT ++ A Sbjct: 97 VILGAGPAHAVYFGTYEFCK----KNLIDSSDTQTHHPFKTAISGA 138
>UCP5_HUMAN (O95258) Brain mitochondrial carrier protein 1 (BMCP-1)| (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14) Length = 325 Score = 62.0 bits (149), Expect = 2e-09 Identities = 35/141 (24%), Positives = 70/141 (49%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I + +G LY+G A LLR G + ++ LK + + L +++CG Sbjct: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICG 148 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 ++G IS+ + P DV+K R+ + G+ +++G+ ++ +EG GL RG+ P + Sbjct: 149 VVSGVISSTIANPTDVLKIRMQAQ-GSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207 Query: 308 ACFAAIGYCAFETARLMILKS 246 A + ++ + ++ S Sbjct: 208 AIVVGVELPVYDITKKHLILS 228 Score = 33.9 bits (76), Expect = 0.45 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLM-------TRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 333 G LA ++ T P+D+ KTRL R R + + + EEG++ L G Sbjct: 47 GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 106 Query: 332 IGPRVLHSACFAAIGYCAFETARLMILK 249 I P +L A + I +++ + + ++ Sbjct: 107 IAPALLRQASYGTIKIGIYQSLKRLFVE 134 Score = 32.0 bits (71), Expect = 1.7 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 6/137 (4%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN--LTPGESVLC 492 + I Q +G GL+ G T R + ++ K + + LT S Sbjct: 185 IDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFT 244 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV-GTMQEVI---AEEGLMGLSRGIGP 324 LAGA+++ P+DVV+TR+M + G + GT+ ++ EG L +G P Sbjct: 245 CGLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWP 301 Query: 323 RVLHSACFAAIGYCAFE 273 L + I + +E Sbjct: 302 NWLRLGPWNIIFFITYE 318 Score = 29.6 bits (65), Expect = 8.6 Identities = 13/39 (33%), Positives = 24/39 (61%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 552 +L++ + +GFF LY G+ LR P ++ + ++E LK Sbjct: 283 ILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
>MFRN1_MOUSE (Q920G8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 338 Score = 62.0 bits (149), Expect = 2e-09 Identities = 41/150 (27%), Positives = 69/150 (46%), Gaps = 8/150 (5%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + +T+G Y Y L N+P + + ++E+L+ + + P ++ G LA Sbjct: 188 VWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRD---YNPQSHIISGGLA 244 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRT--------VVGTMQEVIAEEGLMGLSRGIGP 324 GA++A TTPLDV KT L T+ S + + V GL G +GI Sbjct: 245 GALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQA 304 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYLES 234 RV++ AI + +E + ++ K LE+ Sbjct: 305 RVIYQMPSTAISWSVYEFFKYILTKRQLEN 334 Score = 31.6 bits (70), Expect = 2.3 Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 318 GA+AG + + P+D VKTR+ + +R ++ G ++ ++ EG RG+ + Sbjct: 52 GAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMM 111 Query: 317 LHSACFAAIGYCAFETAR 264 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>MFRN1_RAT (Q66H23) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 338 Score = 61.6 bits (148), Expect = 2e-09 Identities = 41/150 (27%), Positives = 68/150 (45%), Gaps = 8/150 (5%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + +T+G Y Y L N+P + + ++E+L+ + + P ++ G LA Sbjct: 188 VWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPRRD---YNPQSHIISGGLA 244 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRT--------VVGTMQEVIAEEGLMGLSRGIGP 324 GA++A TTPLDV KT L T+ S + + V GL G +GI Sbjct: 245 GALAAAATTPLDVCKTLLNTQENMALSLANVSGRLSGMANAFRTVYQLNGLAGYFKGIQA 304 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYLES 234 RV++ AI + +E + + K LE+ Sbjct: 305 RVIYQMPSTAISWSVYEFFKYFLTKRQLEN 334 Score = 31.6 bits (70), Expect = 2.3 Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 318 GA+AG + + P+D VKTR+ + +R ++ G ++ ++ EG RG+ + Sbjct: 52 GAMAGILEHSIMYPVDSVKTRMQSLNPDPKARYTSIYGALKRIMHTEGFWRPLRGLNVMM 111 Query: 317 LHSACFAAIGYCAFETAR 264 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>COLT_DROME (Q9VQG4) Congested-like trachea protein| Length = 306 Score = 61.2 bits (147), Expect = 3e-09 Identities = 37/129 (28%), Positives = 66/129 (51%), Gaps = 5/129 (3%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++ + G ++ G AT+LR+LPA L + +E L+ A SKS ++ ++ G + Sbjct: 164 KLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKSKSETGQISTASTIFAGGV 223 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL---- 315 AG L P DV+K+RL + + +++I ++G + L RG+ P +L Sbjct: 224 AGMAYWILGMPADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFP 283 Query: 314 -HSACFAAI 291 ++ACF I Sbjct: 284 ANAACFFGI 292
>GHC2_HUMAN (Q9H1K4) Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+)| symporter 2) (Solute carrier family 25 member 18) Length = 315 Score = 60.8 bits (146), Expect = 3e-09 Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 3/119 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 ++L+T G GLY G ATLLR++P ++ + F L ++ A + S + G + Sbjct: 172 ELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNEL-AGKASFAHSFVSGCV 230 Query: 482 AGAISAGLTTPLDVVKTRLMT---RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 AG+I+A TPLDV+KTR+ T +G + +++ +EG +G G R L Sbjct: 231 AGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRAL 289 Score = 46.2 bits (108), Expect = 9e-05 Identities = 37/155 (23%), Positives = 65/155 (41%), Gaps = 24/155 (15%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++ + +GFFG+Y G A L P + ++ ++ + + NL +L G Sbjct: 52 LMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLK--MEMLAG 109 Query: 488 ALAGAISAGLTTPLDVVKTRLM----TRVGAQGSRTVVGTMQ------------------ 375 AG +T P++++K +L V QGS + T + Sbjct: 110 CGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLI 169 Query: 374 --EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 276 E++ +GL GL RG+G +L F+ I + F Sbjct: 170 AWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLF 204 Score = 35.8 bits (81), Expect = 0.12 Identities = 24/101 (23%), Positives = 43/101 (42%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 G +AG + P+D+ KTRL + G + ++ + + EG G+ RG + Sbjct: 15 GGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTL 74 Query: 311 SACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAA 189 AI A + R ++++ + +R EM G A Sbjct: 75 VTPEKAIKLAANDFFRRLLME---DGMQRNLKMEMLAGCGA 112
>ORNT2_HUMAN (Q9BXI2) Mitochondrial ornithine transporter 2 (Solute carrier| family 25 member 2) Length = 301 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 2/139 (1%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 IL+ DG G Y G ++TLL+ P + +E ++F S + L P +L G +A Sbjct: 160 ILKKDGPLGFYHGLSSTLLQEGPGYFFFFGGYELSRSFFASGRSKDELGPVHLMLSGGVA 219 Query: 479 GAISAGLTTPLDVVKTRL--MTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 G + P+D +K+R+ ++ G Q +GT+ V+ EG++ L G+ ++ + Sbjct: 220 GICLWLIVFPVDCIKSRIQVLSMYGKQAG--FIGTLLSVVRNEGIVALYSGLKATMIRAI 277 Query: 305 CFAAIGYCAFETARLMILK 249 + A+E +R M++K Sbjct: 278 PANGALFVAYEYSRKMMMK 296 Score = 35.0 bits (79), Expect = 0.20 Identities = 14/48 (29%), Positives = 28/48 (58%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNA 525 LL +++ +G LY+G AT++R +PA + ++EY + + + A Sbjct: 253 LLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMMKQLEA 300
>AGC1_ASHGO (Q75AH6) Mitochondrial aspartate-glutamate transporter AGC1| (Aspartate-glutamate carrier 1) Length = 911 Score = 60.5 bits (145), Expect = 5e-09 Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 13/144 (9%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGES----- 501 + +++ G GLY G A LLR++P + Y +A KSN N P +S Sbjct: 663 ISVIKNLGLIGLYRGAGACLLRDIPFSAI------YFPTYAHIKSNVFNFDPKDSDKRNK 716 Query: 500 ------VLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMG 345 ++ G LAG +A LTTP DV+KTRL + G + + ++ EEG+ Sbjct: 717 LNTWQLLVSGGLAGMPAAFLTTPFDVIKTRLQIDPKKGESVYNGIWDAARTILKEEGIKS 776 Query: 344 LSRGIGPRVLHSACFAAIGYCAFE 273 +G RVL S+ A+E Sbjct: 777 FFKGGPARVLRSSPQFGFTLAAYE 800 Score = 57.4 bits (137), Expect = 4e-08 Identities = 43/128 (33%), Positives = 65/128 (50%), Gaps = 2/128 (1%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 LL+IL +G GLY+G L+ P + + ++++A + +L P E ++ G Sbjct: 567 LLKILSKEGVRGLYSGLGPQLIGVAPEKAIKLTVNDHMRATLAGRDGKLSL-PCE-IISG 624 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVG--AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 A AGA T PL++VK RL + A +R V + VI GL+GL RG G +L Sbjct: 625 ATAGACQVVFTNPLEIVKIRLQVKSDYVADAARNSVNAI-SVIKNLGLIGLYRGAGACLL 683 Query: 314 HSACFAAI 291 F+AI Sbjct: 684 RDIPFSAI 691 Score = 44.3 bits (103), Expect = 3e-04 Identities = 21/67 (31%), Positives = 41/67 (61%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 G++AG I A + P+D+VKTR+ + + + + +++++EG+ GL G+GP+++ Sbjct: 530 GSVAGCIGAMVVYPIDMVKTRMQAQRDFSKYKNSIDCLLKILSKEGVRGLYSGLGPQLIG 589 Query: 311 SACFAAI 291 A AI Sbjct: 590 VAPEKAI 596
>CMC1_PONPY (Q5RBC8) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC-G 489 L +L+ G FGLY G A LR++P + + + + K ++ G ++L G Sbjct: 469 LNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVG---GLNLLAAG 525 Query: 488 ALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 A+AG +A L TP DV+KTRL R G V+ ++++ EEG +G RV Sbjct: 526 AMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVF 585 Query: 314 HSA 306 S+ Sbjct: 586 RSS 588 Score = 47.8 bits (112), Expect = 3e-05 Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK-AFALSKSNAPNLTPGESVLCGA 486 ++L+ +GFFGLY G L+ P + + ++++ F + P P E VL G Sbjct: 378 KVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP--LPAE-VLAGG 434 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 AG T PL++VK RL +V + + + V+ + G+ GL +G L Sbjct: 435 CAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDI 492 Query: 305 CFAAIGYCAFETARLMI 255 F+AI + + +L++ Sbjct: 493 PFSAIYFPVYAHCKLLL 509 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 9/76 (11%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---------QEVIAEEGLMGLS 339 G++AGA+ A P+D+VKTR+ + +GS +VVG + ++V+ EG GL Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQ---RGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389 Query: 338 RGIGPRVLHSACFAAI 291 RG+ P+++ A AI Sbjct: 390 RGLIPQLIGVAPEKAI 405
>CMC1_HUMAN (O75746) Calcium-binding mitochondrial carrier protein Aralar1| (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Length = 678 Score = 60.1 bits (144), Expect = 6e-09 Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 3/123 (2%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC-G 489 L +L+ G FGLY G A LR++P + + + + K ++ G ++L G Sbjct: 469 LNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVG---GLNLLAAG 525 Query: 488 ALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 A+AG +A L TP DV+KTRL R G V+ ++++ EEG +G RV Sbjct: 526 AMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVF 585 Query: 314 HSA 306 S+ Sbjct: 586 RSS 588 Score = 47.8 bits (112), Expect = 3e-05 Identities = 37/137 (27%), Positives = 65/137 (47%), Gaps = 1/137 (0%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK-AFALSKSNAPNLTPGESVLCGA 486 ++L+ +GFFGLY G L+ P + + ++++ F + P P E VL G Sbjct: 378 KVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP--LPAE-VLAGG 434 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 AG T PL++VK RL +V + + + V+ + G+ GL +G L Sbjct: 435 CAGGSQVIFTNPLEIVKIRL--QVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDI 492 Query: 305 CFAAIGYCAFETARLMI 255 F+AI + + +L++ Sbjct: 493 PFSAIYFPVYAHCKLLL 509 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 9/76 (11%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---------QEVIAEEGLMGLS 339 G++AGA+ A P+D+VKTR+ + +GS +VVG + ++V+ EG GL Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQ---RGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389 Query: 338 RGIGPRVLHSACFAAI 291 RG+ P+++ A AI Sbjct: 390 RGLIPQLIGVAPEKAI 405
>MFRN2_HUMAN (Q96A46) Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute| carrier family 25 member 28) (Mitochondrial RNA splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) Length = 364 Score = 59.7 bits (143), Expect = 8e-09 Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 7/144 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + Q +G Y Y L N+P + + ++E+L+ + P VL GA A Sbjct: 215 VWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHFNPQRR---YNPSSHVLSGACA 271 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-------TMQEVIAEEGLMGLSRGIGPR 321 GA++A TTPLDV KT L T+ + + G + V G+ RG+ R Sbjct: 272 GAVAAAATTPLDVCKTLLNTQESLALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQAR 331 Query: 320 VLHSACFAAIGYCAFETARLMILK 249 V++ AI + +E + +I K Sbjct: 332 VIYQIPSTAIAWSVYEFFKYLITK 355 Score = 31.6 bits (70), Expect = 2.3 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 10/77 (12%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTMQEVIAEEGLMGLSRGI- 330 ++ GA+AG + + P+D VKTR+ + A R V+ + +I EGL RG+ Sbjct: 76 MVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTEGLWRPMRGLN 135 Query: 329 ------GP-RVLHSACF 300 GP L+ AC+ Sbjct: 136 VTATGAGPAHALYFACY 152
>CG69_HUMAN (Q9BZJ4) Mitochondrial carrier protein CGI-69| Length = 359 Score = 59.7 bits (143), Expect = 8e-09 Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 8/132 (6%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 G+ L+ G+ T LR++P L + ++E +K++ + G S + G ++G ++A Sbjct: 211 GWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGLRPKDQTSVGMSFVAGGISGTVAA 270 Query: 464 GLTTPLDVVKTRLMTRVGAQGSRTVVG--------TMQEVIAEEGLMGLSRGIGPRVLHS 309 LT P DVVKT+ +GA + V ++ + AE G GL G PR++ + Sbjct: 271 VLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKA 330 Query: 308 ACFAAIGYCAFE 273 A AI +E Sbjct: 331 APSCAIMISTYE 342 Score = 53.1 bits (126), Expect = 7e-07 Identities = 39/158 (24%), Positives = 83/158 (52%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 ++I++ +G L++G ATL+ +PA + +++++ LKAF ++ +L ++ GA Sbjct: 112 VKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLY--APMVAGA 169 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 LA + + +PL++++T+L + R + ++ +A+ G L G GP L Sbjct: 170 LARLGTVTVISPLELMRTKLQAQ--HVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDV 227 Query: 305 CFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVA 192 F+A+ + +E ++KS+L K D+ G++ Sbjct: 228 PFSALYWFNYE-----LVKSWLNGLRPK--DQTSVGMS 258
>UCP2_RAT (P56500) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G LY G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGI--GSRLLAG 123 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQ---EVIAEEGLMGLSRGIGPRV 318 + GA++ + P DVVK R + A G R T++ + EEG+ GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNV 183 Query: 317 LHSACFAAIGYCAFETARLMILKSYL 240 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCTELVTYDLIKDTLLKANL 209 Score = 33.5 bits (75), Expect = 0.59 Identities = 30/140 (21%), Positives = 57/140 (40%), Gaps = 1/140 (0%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + + RN +++ +K L + + P A Sbjct: 166 IAREEGIRGLWKGTSPNVARNAIVNCTELVTYDLIKDTLLKANLMTDDLPCHFTSAFG-A 224 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRGIGPRVLHSAC 303 G + + +P+DVVKTR M A G G ++ +EG +G P L Sbjct: 225 GFCTTVIASPVDVVKTRYMN--SALGQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGS 282 Query: 302 FAAIGYCAFETARLMILKSY 243 + + + +E + ++ +Y Sbjct: 283 WNVVMFVTYEQLKRALMAAY 302 Score = 30.4 bits (67), Expect = 5.0 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Frame = -3 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQG---------SRTVVGTMQEVIAEEGLMGLSRGI 330 A I+ +T PLD K RL + +QG R V+GT+ ++ EG L G+ Sbjct: 23 AACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVRTEGPRSLYNGL 82 Query: 329 GPRVLHSACFAAIGYCAFETARLMILK 249 + FA++ +++ + K Sbjct: 83 VAGLQRQMSFASVRIGLYDSVKQFYTK 109
>UCP2_MOUSE (P70406) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G LY G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGI--GSRLLAG 123 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQ---EVIAEEGLMGLSRGIGPRV 318 + GA++ + P DVVK R + A G R T++ + EEG+ GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNV 183 Query: 317 LHSACFAAIGYCAFETARLMILKSYL 240 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDTLLKANL 209 Score = 33.5 bits (75), Expect = 0.59 Identities = 30/140 (21%), Positives = 57/140 (40%), Gaps = 1/140 (0%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + + RN +++ +K L + + P A Sbjct: 166 IAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLLKANLMTDDLPCHFTSAFG-A 224 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRGIGPRVLHSAC 303 G + + +P+DVVKTR M A G G ++ +EG +G P L Sbjct: 225 GFCTTVIASPVDVVKTRYMN--SALGQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGS 282 Query: 302 FAAIGYCAFETARLMILKSY 243 + + + +E + ++ +Y Sbjct: 283 WNVVMFVTYEQLKRALMAAY 302 Score = 30.4 bits (67), Expect = 5.0 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Frame = -3 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQG---------SRTVVGTMQEVIAEEGLMGLSRGI 330 A I+ +T PLD K RL + +QG R V+GT+ ++ EG L G+ Sbjct: 23 AACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNGL 82 Query: 329 GPRVLHSACFAAIGYCAFETARLMILK 249 + FA++ +++ + K Sbjct: 83 VAGLQRQMSFASVRIGLYDSVKQFYTK 109
>UCP2_HUMAN (P55851) Mitochondrial uncoupling protein 2 (UCP 2) (UCPH)| Length = 309 Score = 59.3 bits (142), Expect = 1e-08 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 3/146 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G LY G A L R + + ++ +K F S ++ G +L G Sbjct: 66 ILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASI--GSRLLAG 123 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSR---TVVGTMQEVIAEEGLMGLSRGIGPRV 318 + GA++ + P DVVK R + A G R + V + + EEG GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNV 183 Query: 317 LHSACFAAIGYCAFETARLMILKSYL 240 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDALLKANL 209 Score = 35.0 bits (79), Expect = 0.20 Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +GF GL+ G + + RN +++ +K AL K+N A Sbjct: 166 IAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKD-ALLKANLMTDDLPCHFTSAFGA 224 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRGIGPRVLHSAC 303 G + + +P+DVVKTR M A G + G ++ +EG +G P L Sbjct: 225 GFCTTVIASPVDVVKTRYMN--SALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGS 282 Query: 302 FAAIGYCAFETARLMIL 252 + + + +E + ++ Sbjct: 283 WNVVMFVTYEQLKRALM 299 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Frame = -3 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGS---------RTVVGTMQEVIAEEGLMGLSRGI 330 A I+ +T PLD K RL + +QG R V+GT+ ++ EG L G+ Sbjct: 23 AACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGL 82 Query: 329 GPRVLHSACFAAIGYCAFETARLMILK 249 + FA++ +++ + K Sbjct: 83 VAGLQRQMSFASVRIGLYDSVKQFYTK 109
>CG69_MOUSE (Q9D8K8) Mitochondrial carrier protein CGI-69 homolog| Length = 359 Score = 58.9 bits (141), Expect = 1e-08 Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 8/132 (6%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 G+ L+ G+ T LR++P L + ++E +K++ + G S + G ++G ++A Sbjct: 211 GWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLSGLRPKDQTSVGISFVAGGISGMVAA 270 Query: 464 GLTTPLDVVKTRLMTRVGAQGSRTVVG--------TMQEVIAEEGLMGLSRGIGPRVLHS 309 LT P DVVKT+ +GA + V ++ + AE G GL G PR++ + Sbjct: 271 TLTLPFDVVKTQRQMSLGAVEAVRVKPPRVDSTWLLLRRIRAESGTRGLFAGFLPRIIKA 330 Query: 308 ACFAAIGYCAFE 273 A AI +E Sbjct: 331 APSCAIMISTYE 342 Score = 58.2 bits (139), Expect = 2e-08 Identities = 41/158 (25%), Positives = 83/158 (52%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 ++I++ +G L++G ATL+ +PA + +++++ LKAF +S +L ++ GA Sbjct: 112 VKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQSLTSDLY--APMVAGA 169 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 LA + + +PL++V+T+L + R + ++Q + + G L G GP L Sbjct: 170 LARMGTVTVVSPLELVRTKLQAQ--HVSYRELASSVQAAVTQGGWRSLWLGWGPTALRDV 227 Query: 305 CFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVA 192 F+A+ + +E ++KS+L K D+ G++ Sbjct: 228 PFSALYWFNYE-----LVKSWLSGLRPK--DQTSVGIS 258
>MFRN_CAEEL (Q23125) Mitoferrin| Length = 312 Score = 58.5 bits (140), Expect = 2e-08 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 14/149 (9%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + +G Y Y L N+P + + S+E+ + L+ + P ++ G LA Sbjct: 159 VYNREGVAAFYRSYTTQLAMNVPFQAIHFMSYEFWQ-HVLNPEH--KYDPKSHLIAGGLA 215 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGS--------------RTVVGTMQEVIAEEGLMGL 342 G ++A LTTP+D VKT L T+ A+ R + ++ + ++ GL G Sbjct: 216 GGLAAALTTPMDCVKTVLNTQQAAEADPANRRIFLQARYRYRGISDAVRTIYSQRGLSGF 275 Query: 341 SRGIGPRVLHSACFAAIGYCAFETARLMI 255 S G+ RV+ A+ + +E + M+ Sbjct: 276 SCGLQARVIFQVPATALSWSVYELFKFML 304 Score = 32.7 bits (73), Expect = 1.0 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 318 GALAGA+ + P D VKTR+ + ++ T V ++ ++ EG + RG+ Sbjct: 24 GALAGAVEHCVMFPFDSVKTRMQSLCPCPETKCPTPVHSLMSIVKREGWLRPLRGVNAVA 83 Query: 317 LHSACFAAIGYCAFETARLMILKSYL 240 S A+ + +E +K YL Sbjct: 84 AGSMPAHALYFTVYEK-----MKGYL 104
>UCP2_CYPCA (Q9W725) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 57.8 bits (138), Expect = 3e-08 Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 3/143 (2%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 +++ +G LY+G A L R + + ++ +K F S + G ++ G Sbjct: 70 MVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHVGI--GSRLMAGCTT 127 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVLHS 309 GA++ L P DVVK R + A ++ GTM + + EEG GL +G GP + + Sbjct: 128 GAMAVALAQPTDVVKVRFQAQNSAGANKRYHGTMDAYRTIAKEEGFRGLWKGTGPNITRN 187 Query: 308 ACFAAIGYCAFETARLMILKSYL 240 A ++ + +LKS L Sbjct: 188 AIVNCTELVTYDLIKDALLKSSL 210 Score = 36.6 bits (83), Expect = 0.070 Identities = 29/129 (22%), Positives = 52/129 (40%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +GF GL+ G + RN +++ +K L S + P A Sbjct: 167 IAKEEGFRGLWKGTGPNITRNAIVNCTELVTYDLIKDALLKSSLMTDDLPCHFTSAFG-A 225 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M Q + + ++ +EG +G P L + Sbjct: 226 GFCTTVIASPVDVVKTRYMNSAPGQYC-SALNCAVAMLTKEGPKAFYKGFMPSFLRLGSW 284 Query: 299 AAIGYCAFE 273 + + +E Sbjct: 285 NVVMFVTYE 293
>UCP2_BRARE (Q9W720) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 310 Score = 57.8 bits (138), Expect = 3e-08 Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 3/143 (2%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 +++ +G LY+G A L R + + ++ +K F S+ + G ++ G Sbjct: 70 MVRVEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSDHAGI--GSRLMAGCTT 127 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVLHS 309 GA++ + P DV+K R +V A S+ TM + + EEG GL +G GP + + Sbjct: 128 GAMAVAVAQPTDVLKVRFQAQVSAGASKRYHSTMDAYRTIAKEEGFRGLWKGTGPNITRN 187 Query: 308 ACFAAIGYCAFETARLMILKSYL 240 A ++ + +LKS L Sbjct: 188 AIVNCTELVTYDLIKDALLKSSL 210 Score = 36.6 bits (83), Expect = 0.070 Identities = 29/129 (22%), Positives = 53/129 (41%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +GF GL+ G + RN +++ +K L S + P A Sbjct: 167 IAKEEGFRGLWKGTGPNITRNAIVNCTELVTYDLIKDALLKSSLMTDDLPCHFTSAFG-A 225 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M Q S + + ++ ++G +G P L + Sbjct: 226 GFCTTIIASPVDVVKTRYMNSAQGQYS-SALNCAVAMLTKKGPKAFFKGFMPSFLRLGSW 284 Query: 299 AAIGYCAFE 273 + + +E Sbjct: 285 NVVMFVTYE 293
>MFRN_CAEBR (Q620A6) Mitoferrin| Length = 311 Score = 57.8 bits (138), Expect = 3e-08 Identities = 34/149 (22%), Positives = 65/149 (43%), Gaps = 14/149 (9%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + +GF Y Y L N+P + + +E+ + + P ++ G LA Sbjct: 158 VYNREGFAAFYRSYTTQLAMNVPFQAIHFMGYEFWQQVLNPEHK---YDPKSHLIAGGLA 214 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGS--------------RTVVGTMQEVIAEEGLMGL 342 G ++A +TTP+D VKT L T+ A+ R + ++ + ++ G+ G Sbjct: 215 GGLAAAVTTPMDCVKTVLNTQQAAEADPSNRRIFLKARYRYRGISDAVRTIYSQRGMAGF 274 Query: 341 SRGIGPRVLHSACFAAIGYCAFETARLMI 255 S G+ RV+ A+ + +E + M+ Sbjct: 275 SCGLQARVIFQVPATALSWSVYELFKFML 303 Score = 35.8 bits (81), Expect = 0.12 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 2/134 (1%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKS--NAPNLTPGESVL 495 L+ I++ +G+ G A ++PA L ++ +E +K+F + + L G S Sbjct: 62 LMSIVKREGWLRPLRGVNAVAAGSMPAHALYFTVYEKMKSFLTGNTAGHEHTLAYGAS-- 119 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 G +A I + P +VVK R+ GS + + V EG R ++ Sbjct: 120 -GVVATLIHDAVMNPAEVVKQRMQMAYSPYGSS--LECARCVYNREGFAAFYRSYTTQLA 176 Query: 314 HSACFAAIGYCAFE 273 + F AI + +E Sbjct: 177 MNVPFQAIHFMGYE 190 Score = 32.3 bits (72), Expect = 1.3 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 1/85 (1%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGS-RTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 GALAGA+ + P D VKTR+ + + T V ++ ++ EG + RG+ Sbjct: 24 GALAGAVEHCVMFPFDSVKTRMQSLCPCETKCPTPVHSLMSIVKREGWLRPLRGVNAVAA 83 Query: 314 HSACFAAIGYCAFETARLMILKSYL 240 S A+ + +E +KS+L Sbjct: 84 GSMPAHALYFTVYEK-----MKSFL 103
>UCP3_MOUSE (P56501) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 57.8 bits (138), Expect = 3e-08 Identities = 41/148 (27%), Positives = 70/148 (47%), Gaps = 5/148 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G Y+G A L R + + ++ +K F K A + + +L G Sbjct: 62 ILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKG-ADHSSVAIRILAG 120 Query: 488 ALAGAISAGLTTPLDVVKTRL--MTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGP 324 GA++ P DVVK R M R+G G R GTM + + EEG+ GL +G P Sbjct: 121 CTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWP 180 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYL 240 + +A ++ + +L+S+L Sbjct: 181 NITRNAIVNCAEMVTYDIIKEKLLESHL 208 Score = 37.0 bits (84), Expect = 0.054 Identities = 31/137 (22%), Positives = 59/137 (43%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + RN +++ +K L + P V A Sbjct: 165 IAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIKEKLLESHLFTDNFPCHFVSAFG-A 223 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M + R+ + M +++A+EG +G P L + Sbjct: 224 GFCATVVASPVDVVKTRYMNAPLGR-YRSPLHCMLKMVAQEGPTAFYKGFVPSFLRLGAW 282 Query: 299 AAIGYCAFETARLMILK 249 + + +E + ++K Sbjct: 283 NVMMFVTYEQLKRALMK 299
>UCP2_PIG (O97562) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 57.4 bits (137), Expect = 4e-08 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 3/146 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++ +G LY G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRNEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKHFYTKGSEHAGI--GSRLLAG 123 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGPRV 318 + GA++ + P DVVK R + A G R+ V + + EEGL GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGGGRRYRSTVDAYKTIAREEGLRGLWKGTSPNV 183 Query: 317 LHSACFAAIGYCAFETARLMILKSYL 240 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDTLLKADL 209 Score = 32.3 bits (72), Expect = 1.3 Identities = 28/136 (20%), Positives = 54/136 (39%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + + RN +++ +K L + P A Sbjct: 166 IAREEGLRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLLKADLMTDDLPCHFTSAFG-A 224 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M Q S + ++ +EG +G P L + Sbjct: 225 GFCTTVIASPVDVVKTRYMNSAPGQYS-SAGHCALTMLQKEGPRAFYKGFTPSFLRLGSW 283 Query: 299 AAIGYCAFETARLMIL 252 + + +E + ++ Sbjct: 284 NVVMFVTYEQLKRALM 299
>UCP2_CANFA (Q9N2J1) Mitochondrial uncoupling protein 2 (UCP 2)| Length = 309 Score = 57.4 bits (137), Expect = 4e-08 Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 3/146 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G LY+G A L R + + ++ +K F S + G +L G Sbjct: 66 ILTMVRTEGPRSLYSGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGI--GSRLLAG 123 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSR---TVVGTMQEVIAEEGLMGLSRGIGPRV 318 + GA++ + P DVVK R + A R + V + + EEG GL +G P V Sbjct: 124 STTGALAVAVAQPTDVVKVRFQAQARAGSGRRYQSTVDAYKTIAREEGFRGLWKGTSPNV 183 Query: 317 LHSACFAAIGYCAFETARLMILKSYL 240 +A ++ + +LK+ L Sbjct: 184 ARNAIVNCAELVTYDLIKDALLKANL 209 Score = 35.0 bits (79), Expect = 0.20 Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +GF GL+ G + + RN +++ +K AL K+N A Sbjct: 166 IAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKD-ALLKANLMTDDLPCHFTSAFGA 224 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRGIGPRVLHSAC 303 G + + +P+DVVKTR M A G + G ++ +EG +G P L Sbjct: 225 GFCTTVIASPVDVVKTRYMN--SALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGS 282 Query: 302 FAAIGYCAFETARLMIL 252 + + + +E + ++ Sbjct: 283 WNVVMFVTYEQLKRALM 299
>YQ51_CAEEL (Q09461) Putative mitochondrial carrier C16C10.1| Length = 360 Score = 57.0 bits (136), Expect = 5e-08 Identities = 34/142 (23%), Positives = 70/142 (49%), Gaps = 4/142 (2%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE-SVLCGALA 480 + T G Y G+ T+LR++P + ++ ++ K L + P+ P S + GA A Sbjct: 220 MATKGISSFYLGWTPTMLRDIPFSGIYWAGYDLFKT-NLQRRQGPDHNPFVVSFVSGAAA 278 Query: 479 GAISAGLTTPLDVVKTRLMTRVGA---QGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 G +++ T P DV+KT R+G ++++ ++++ G+ S G+ PR++ Sbjct: 279 GVVASIFTHPFDVIKTNCQIRIGGSIDDMNKSITTVIKDMYHSRGISAFSSGLVPRLVKV 338 Query: 308 ACFAAIGYCAFETARLMILKSY 243 + AI +E + + K++ Sbjct: 339 SPSCAIMISFYEYFKFLFQKNH 360
>TXTP_CAEEL (P34519) Putative tricarboxylate transport protein, mitochondrial| precursor (Citrate transport protein) (CTP) Length = 312 Score = 57.0 bits (136), Expect = 5e-08 Identities = 42/136 (30%), Positives = 66/136 (48%), Gaps = 3/136 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 Q + GFFGLY G + L ++P + +FEYLK+ A + NL+P +LCG Sbjct: 73 QTVNGHGFFGLYRGLSVLLYGSIPKSSFRFGTFEYLKSQAADERG--NLSPVMRLLCGLG 130 Query: 482 AGAISAGL-TTPLDVVKTRLMTRVG-AQGS-RTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 AG A TP++ VK + + G AQ + V + ++ EGL G+ +G+ + Sbjct: 131 AGLSEAVFAVTPMETVKVKFIHDQGLAQPKYKGFVHGVGCIVKAEGLGGIYKGVTATMAK 190 Query: 311 SACFAAIGYCAFETAR 264 AI + ET + Sbjct: 191 QGSNQAIRFFVMETLK 206 Score = 50.4 bits (119), Expect = 5e-06 Identities = 34/130 (26%), Positives = 60/130 (46%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I++ +G G+Y G AT+ + + + E LK + N ++ L GA+A Sbjct: 171 IVKAEGLGGIYKGVTATMAKQGSNQAIRFFVMETLKDWYRGGDNTQPISKPIVGLMGAVA 230 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 GA S TP+DVVKTR M + A+ + + ++ +EG +G PR+ Sbjct: 231 GAASVYGNTPIDVVKTR-MQGLEAKKYKNTLDCAMQIWKKEGFFAFYKGTVPRLSRVCLD 289 Query: 299 AAIGYCAFET 270 I + +++ Sbjct: 290 VGITFMIYDS 299
>ORNT1_MOUSE (Q9WVD5) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 56.2 bits (134), Expect = 9e-08 Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 1/138 (0%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 +I + DG G Y G ++TLLR +P + +E ++F S + L P +L G Sbjct: 159 EIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGF 218 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 G P+D +K+R+ + G +T +V T ++ EG+ L G+ P ++ + Sbjct: 219 GGICLWLAVYPVDCIKSRIQV-LSMTGKQTGLVRTFLSIVKNEGITALYSGLKPTMIRAF 277 Query: 305 CFAAIGYCAFETARLMIL 252 + A+E +R +++ Sbjct: 278 PANGALFLAYEYSRKLMM 295 Score = 31.2 bits (69), Expect = 2.9 Identities = 13/47 (27%), Positives = 26/47 (55%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNA 525 L I++ +G LY+G T++R PA + ++EY + +++ A Sbjct: 254 LSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEA 300
>ORNT1_HUMAN (Q9Y619) Mitochondrial ornithine transporter 1 (Solute carrier| family 25 member 15) Length = 301 Score = 56.2 bits (134), Expect = 9e-08 Identities = 34/136 (25%), Positives = 63/136 (46%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 IL+ DG G Y G ++TLLR +P + +E ++F S + L P +L G + Sbjct: 160 ILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPVPLMLSGGVG 219 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G P+D +K+R+ + + T V+ EG+ L G+ P ++ + Sbjct: 220 GICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPA 279 Query: 299 AAIGYCAFETARLMIL 252 + A+E +R +++ Sbjct: 280 NGALFLAYEYSRKLMM 295 Score = 30.0 bits (66), Expect = 6.6 Identities = 11/47 (23%), Positives = 26/47 (55%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNA 525 + +++ +G LY+G T++R PA + ++EY + +++ A Sbjct: 254 INVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEA 300
>MCAT_HUMAN (O43772) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 56.2 bits (134), Expect = 9e-08 Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 1/133 (0%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK-AFALSKSNAPNLTPGESVLCGA 486 ++ Q G G+Y G TL+R++PA + + ++E+LK F L+ ++ G Sbjct: 158 KLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGG 217 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 +AG + + P DV+K+R T + ++E+I +EG+ L +G ++ + Sbjct: 218 IAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAF 277 Query: 305 CFAAIGYCAFETA 267 A + FE A Sbjct: 278 PANAACFLGFEVA 290
>SFC1_YEAST (P33303) Succinate/fumarate mitochondrial transporter (Regulator of| acetyl-CoA synthetase activity) Length = 322 Score = 56.2 bits (134), Expect = 9e-08 Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I++ +G LY G + T R +++ + LK F + L E+ G ++ Sbjct: 165 IVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMDVLPSWETSCIGLIS 224 Query: 479 GAISAGLTTPLDVVKTRL-----MTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 GAI PLD +KTRL ++ G + ++ +++ EEG L +GI PRV+ Sbjct: 225 GAIGPFSNAPLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLLKEEGFRALYKGITPRVM 284 Query: 314 HSACFAAIGYCAFETAR 264 A A+ + +E R Sbjct: 285 RVAPGQAVTFTVYEYVR 301 Score = 47.8 bits (112), Expect = 3e-05 Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 8/118 (6%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I Q +GF LY G A ++ +P + +SS+E+ + ++K + ++ G + + G A Sbjct: 62 IYQKEGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESG-IVSTGNTFVAGVGA 120 Query: 479 GAISAGL-TTPLDVVKTRLMTR-------VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 G A L P++VVK RL + + ++ EEG+ L RG+ Sbjct: 121 GITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYRGV 178 Score = 35.0 bits (79), Expect = 0.20 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Frame = -3 Query: 512 PGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTV-----VGTMQEVIAEEGLM 348 P +++ G AG A PLD +K R+ G V + T + + +EG + Sbjct: 10 PAINLMAGGTAGLFEALCCHPLDTIKVRMQIYRRVAGIEHVKPPGFIKTGRTIYQKEGFL 69 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMIL 252 L +G+G V+ AI + ++E R +++ Sbjct: 70 ALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLV 101 Score = 30.0 bits (66), Expect = 6.6 Identities = 11/37 (29%), Positives = 23/37 (62%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 552 Q+L+ +GF LY G ++R P ++++ +EY++ Sbjct: 265 QLLKEEGFRALYKGITPRVMRVAPGQAVTFTVYEYVR 301
>CMC2_CAEEL (Q20799) Probable calcium-binding mitochondrial carrier F55A11.4| Length = 588 Score = 56.2 bits (134), Expect = 9e-08 Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 1/142 (0%) Frame = -3 Query: 665 LQILQTDGFF-GLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++L +G + G +++ P + + ++ LK K ++ E + G Sbjct: 292 LKLLHAEGGIKSFWRGNGINVIKIAPESAIKFMCYDQLKRLIQKKKGNEEISTFERLCAG 351 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 + AGAIS P++V+KTRL R Q R ++ ++ +EG+ +G P ++ Sbjct: 352 SAAGAISQSTIYPMEVMKTRLALRKTGQLDRGIIHFAHKMYTKEGIRCFYKGYLPNLIGI 411 Query: 308 ACFAAIGYCAFETARLMILKSY 243 +A I +ET + ++ Y Sbjct: 412 IPYAGIDLAIYETLKRTYVRYY 433 Score = 46.2 bits (108), Expect = 9e-05 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 6/134 (4%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL--CGALAGA 474 +G Y GY L+ +P + + +E LK + + PG L CG + Sbjct: 395 EGIRCFYKGYLPNLIGIIPYAGIDLAIYETLKRTYVRYYETNSSEPGVLALLACGTCSST 454 Query: 473 ISAGLTTPLDVVKTRL----MTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 + P +V+TRL +TR Q T+ G + ++ EG+ G RGI P L Sbjct: 455 CGQLSSYPFALVRTRLQALSITRYSPQPD-TMFGQFKYILQNEGVTGFYRGITPNFLKVI 513 Query: 305 CFAAIGYCAFETAR 264 +I Y +E R Sbjct: 514 PAVSISYVVYEKVR 527 Score = 37.7 bits (86), Expect = 0.031 Identities = 23/84 (27%), Positives = 39/84 (46%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 ++ G AGA+S T P D +K L V+ ++ + AE G+ RG G Sbjct: 252 LVAGGAAGAVSRTCTAPFDRIKVYLQVNSSKTNRLGVMSCLKLLHAEGGIKSFWRGNGIN 311 Query: 320 VLHSACFAAIGYCAFETARLMILK 249 V+ A +AI + ++ + +I K Sbjct: 312 VIKIAPESAIKFMCYDQLKRLIQK 335
>MFRN1_BRARE (Q287T7) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Protein frascati) Length = 332 Score = 56.2 bits (134), Expect = 9e-08 Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 8/140 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L + + +G Y Y+ L N+P + + ++E+++ + P ++ G Sbjct: 173 VLMVSRKEGLAAFYRSYSTQLTMNIPFQAVHFITYEFMQEHF---NPHRQYRPETHIISG 229 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT--------VVGTMQEVIAEEGLMGLSRG 333 A AGA+SA +TTPLDV KT L T+ S +V ++ V G+ +G Sbjct: 230 AAAGAVSAAVTTPLDVCKTLLNTQENVALSSAHVSGHLSGMVNALRTVYRLGGVPAFFKG 289 Query: 332 IGPRVLHSACFAAIGYCAFE 273 I RV++ AI + +E Sbjct: 290 IQARVIYQMPSTAIAWSVYE 309 Score = 38.1 bits (87), Expect = 0.024 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 2/110 (1%) Frame = -3 Query: 509 GESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSR 336 G + GA+AG + + P+D VKTR+ + + R+V G ++ ++ EGL+ R Sbjct: 34 GTHMTAGAVAGILEHTVMYPVDSVKTRMQSLQPDPKAQYRSVYGALKRIVRTEGLLRPLR 93 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAAA 186 G+ VL + A+ + +E I +S + + + GVA + Sbjct: 94 GLNITVLGAGPAHALYFACYE----RIKRSLSDVIQNGGNSHIANGVAGS 139
>MCAT_MOUSE (Q9Z2Z6) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (mCAC) (Solute carrier family 25 member 20) Length = 301 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 1/133 (0%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK-AFALSKSNAPNLTPGESVLCGA 486 ++ Q G G Y G TL+R++PA + + ++E+LK F + +L+ ++ G Sbjct: 158 KLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPEGKSVSDLSVPRILVAGG 217 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 AG + + P DV+K+R T + ++E+I EEG+ L +G ++ + Sbjct: 218 FAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAF 277 Query: 305 CFAAIGYCAFETA 267 A + FE A Sbjct: 278 PANAACFLGFEIA 290 Score = 35.8 bits (81), Expect = 0.12 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 10/87 (11%) Frame = -3 Query: 518 LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV--GTM---QEVIAEEG 354 ++P +++L G G + PLD VK RL T+ + + + GT+ ++ + EG Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67 Query: 353 LMGLSRG-----IGPRVLHSACFAAIG 288 + GL RG IG + + CF G Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFG 94
>CMC3_CAEEL (Q19529) Probable calcium-binding mitochondrial carrier F17E5.2| Length = 531 Score = 55.5 bits (132), Expect = 1e-07 Identities = 34/139 (24%), Positives = 62/139 (44%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 G + G +++ P + + ++ +K + L+ E +L G+ AGAIS Sbjct: 296 GIKSFWRGNGINVIKIAPESAMKFMCYDQIKRWMQEYKGGAELSTIERLLAGSSAGAISQ 355 Query: 464 GLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGY 285 P++V+KTRL R Q + + ++ +EG+ +G P +L +A I Sbjct: 356 TAIYPMEVMKTRLALRRTGQLDKGMFHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGIDL 415 Query: 284 CAFETARLMILKSYLESCE 228 +E+ + M K Y E E Sbjct: 416 TVYESLKSMYTKYYTEHTE 434 Score = 52.0 bits (123), Expect = 2e-06 Identities = 38/134 (28%), Positives = 58/134 (43%), Gaps = 6/134 (4%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL--CGALAGA 474 +G Y GY LL +P + + +E LK+ +K + PG L CG + Sbjct: 391 EGIKCFYKGYLPNLLGIIPYAGIDLTVYESLKSM-YTKYYTEHTEPGVLALLACGTCSST 449 Query: 473 ISAGLTTPLDVVKTRLMTRV----GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 + PL +V+TRL R + T+VG + ++ EG GL RGI P + Sbjct: 450 CGQLASYPLALVRTRLQARAISPKNSTQPDTMVGQFKHILQTEGFTGLYRGITPNFMKVI 509 Query: 305 CFAAIGYCAFETAR 264 +I Y +E R Sbjct: 510 PAVSISYVVYEKVR 523 Score = 35.4 bits (80), Expect = 0.16 Identities = 25/104 (24%), Positives = 45/104 (43%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 ++ G +AGA+S T P D +K L VV + + AE G+ RG G Sbjct: 248 LVAGGVAGAMSRTCTAPFDRIKVYLQVNSTKTNKLGVVSCVHLLHAEGGIKSFWRGNGIN 307 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAA 189 V+ A +A+ + ++ + ++ Y E + + G +A Sbjct: 308 VIKIAPESAMKFMCYDQIKRW-MQEYKGGAELSTIERLLAGSSA 350 Score = 34.3 bits (77), Expect = 0.35 Identities = 15/36 (41%), Positives = 23/36 (63%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 552 ILQT+GF GLY G ++ +PA +SY +E ++ Sbjct: 488 ILQTEGFTGLYRGITPNFMKVIPAVSISYVVYEKVR 523
>UCP3_RAT (P56499) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 55.5 bits (132), Expect = 1e-07 Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 5/148 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G Y+G A L R + + ++ +K F K + + +L G Sbjct: 62 ILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGT-DHSSVAIRILAG 120 Query: 488 ALAGAISAGLTTPLDVVKTRL--MTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGP 324 GA++ P DVVK R M R+G G R GTM + + EEG+ GL +G P Sbjct: 121 CTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWP 180 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYL 240 + +A ++ + +L S+L Sbjct: 181 NITRNAIVNCAEMVTYDIIKEKLLDSHL 208 Score = 37.0 bits (84), Expect = 0.054 Identities = 31/137 (22%), Positives = 58/137 (42%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + RN +++ +K L + P V A Sbjct: 165 IAREEGVRGLWKGTWPNITRNAIVNCAEMVTYDIIKEKLLDSHLFTDNFPCHFVSAFG-A 223 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M + R+ + M ++A+EG +G P L + Sbjct: 224 GFCATVVASPVDVVKTRYMNAPPGR-YRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSW 282 Query: 299 AAIGYCAFETARLMILK 249 + + +E + ++K Sbjct: 283 NVMMFVTYEQLKRALMK 299
>YEA6_YEAST (P39953) Putative mitochondrial carrier YEL006W| Length = 335 Score = 55.5 bits (132), Expect = 1e-07 Identities = 37/120 (30%), Positives = 64/120 (53%), Gaps = 5/120 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPGESVLCGAL 483 I + +G GLY G T+L +P ++ +S +++ + +++ ++P L+ S + Sbjct: 91 IFKDEGAAGLYKGLQPTVLGYIPTLMIYFSVYDFCRKYSVDIFPHSPFLSNASSAIT--- 147 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRT----VVGTMQEVIAEEGLMGLSRGIGPRVL 315 AGAIS T P+ VVKTRLM + G T + T +++I +EG L G+ P +L Sbjct: 148 AGAISTVATNPIWVVKTRLMLQTGIGKYSTHYKGTIDTFRKIIQQEGAKALYAGLVPALL 207 Score = 48.5 bits (114), Expect = 2e-05 Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 6/109 (5%) Frame = -3 Query: 521 NLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTR------VGAQGSRTVVGTMQEVIAE 360 N P + + GAL+GA+SA L P DV KTRL + +Q + GT + + Sbjct: 35 NADPRVAAISGALSGALSAMLVCPFDVAKTRLQAQGLQNMTHQSQHYKGFFGTFATIFKD 94 Query: 359 EGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKAAD 213 EG GL +G+ P VL GY LMI S + C + + D Sbjct: 95 EGAAGLYKGLQPTVL--------GY----IPTLMIYFSVYDFCRKYSVD 131 Score = 39.7 bits (91), Expect = 0.008 Identities = 16/34 (47%), Positives = 24/34 (70%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF 546 +GF G Y+G+A L+R +PA V++ SFEY K + Sbjct: 296 EGFAGFYSGFATNLVRTVPAAVVTLVSFEYSKKY 329
>MCAT_MACFA (Q8HXY2) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 55.1 bits (131), Expect = 2e-07 Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 1/133 (0%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK-AFALSKSNAPNLTPGESVLCGA 486 ++ Q G G+Y G TL+R++PA + + ++E++K F L+ ++ G Sbjct: 158 KLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKNIFTPEGKRVSELSVPRVLVAGG 217 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 +AG + + P DV+K+R T + ++E+I +EG+ L +G ++ + Sbjct: 218 IAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIPDEGVTSLYKGFNAVMIRAF 277 Query: 305 CFAAIGYCAFETA 267 A + FE A Sbjct: 278 PANAACFLGFEVA 290
>YG5F_YEAST (P53320) Putative mitochondrial carrier YGR257C| Length = 366 Score = 54.7 bits (130), Expect = 2e-07 Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 8/141 (5%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 +I +G L+ G + TLL +PA ++ +S +EY++ + S P L P + CGA+ Sbjct: 111 KIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIRDVSPIASTYPTLNP---LFCGAI 167 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR----GIG 327 A +A PL++VKT+L + + S V + E E ++G SR G+ Sbjct: 168 ARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMVGPSRALFKGLE 227 Query: 326 PRVLHSACFAAIGYCAFETAR 264 + F+AI + ++E + Sbjct: 228 ITLWRDVPFSAIYWSSYELCK 248 Score = 44.3 bits (103), Expect = 3e-04 Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 15/138 (10%) Frame = -3 Query: 632 LYAGYAATLLRNLPAGVLSYSSFEYLKA--------FALSKSNAPNLTPGESVLCGALAG 477 L+ G TL R++P + +SS+E K FA +N + S G ++G Sbjct: 222 LFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFI--NSFASGCISG 279 Query: 476 AISAGLTTPLDVVKTRLMTRV-------GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 318 I+A T P DV KTR + G SR + ++ + EGL L G+ RV Sbjct: 280 MIAAICTHPFDVGKTRWQISMMNNSDPKGGNRSRNMFKFLETIWRTEGLAALYTGLAARV 339 Query: 317 LHSACFAAIGYCAFETAR 264 + AI ++E ++ Sbjct: 340 IKIRPSCAIMISSYEISK 357
>DNC_HUMAN (Q9HC21) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) (Mitochondrial uncoupling protein 1) Length = 320 Score = 54.3 bits (129), Expect = 3e-07 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 13/132 (9%) Frame = -3 Query: 629 YAGYAATLLRNLPAGVLS---YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGL 459 Y G A TL+ P L YSS ++L +A+ N +++LCG+ AG IS L Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVISKTL 233 Query: 458 TTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGLMGLSRGIGPRVLHS 309 T PLD+ K RL G + +R G + ++V+ +EG +G +G+ P +L + Sbjct: 234 TYPLDLFKKRLQVG-GFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292 Query: 308 ACFAAIGYCAFE 273 A + ++E Sbjct: 293 ALSTGFMFFSYE 304 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 4/137 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 QILQ +G + G+ + ++ G + + SFE L S +CG L Sbjct: 68 QILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGL 127 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIA----EEGLMGLSRGIGPRVL 315 A ++ P+DV++TR AQG V T++ + EG +G+ P ++ Sbjct: 128 AACMATLTVHPVDVLRTRF----AAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLI 183 Query: 314 HSACFAAIGYCAFETAR 264 +A + + + + + Sbjct: 184 AIFPYAGLQFSCYSSLK 200 Score = 33.9 bits (76), Expect = 0.45 Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 7/95 (7%) Frame = -3 Query: 536 KSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTR----VGAQGSRTVVGTMQ-- 375 K + N T + + G+++G ++ L +P DV+K R + + S G +Q Sbjct: 7 KPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQAS 66 Query: 374 -EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 273 +++ EEG +G P + S + A+ + +FE Sbjct: 67 RQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFE 101
>YHM1_YEAST (P38988) Putative mitochondrial carrier protein YHM1/SHM1| Length = 300 Score = 53.1 bits (126), Expect = 7e-07 Identities = 28/117 (23%), Positives = 55/117 (47%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 ++IL+ +G F LY G+ T RN P + + K + L + T ++ + Sbjct: 159 IKILRDEGLFNLYRGWGWTAARNAPGSFALFGGNAFAKEYILGLKDYSQATWSQNFISSI 218 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 + S ++ PLDV+KTR+ R + + ++ + EG+ +G+ P++L Sbjct: 219 VGACSSLIVSAPLDVIKTRIQNR-NFDNPESGLRIVKNTLKNEGVTAFFKGLTPKLL 274
>MCAT_RAT (P97521) Mitochondrial carnitine/acylcarnitine carrier protein| (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20) Length = 301 Score = 52.8 bits (125), Expect = 9e-07 Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 6/127 (4%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK-AFALSKSNAPNLTPGESVLCGA 486 ++ Q G G Y G A TL+R++PA + + ++E+LK F + +L+ ++ G Sbjct: 158 KLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQGKSVHDLSVPRVLVAGG 217 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL--- 315 G + + P DV+K+R T + ++E+I EEG+ L +G ++ Sbjct: 218 FRGIFNWVVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKGFNAVMIRAF 277 Query: 314 --HSACF 300 ++ACF Sbjct: 278 PANAACF 284 Score = 34.7 bits (78), Expect = 0.27 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 10/87 (11%) Frame = -3 Query: 518 LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEG 354 ++P +++L G G + PLD VK RL T+ + + + ++ + EG Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67 Query: 353 LMGLSRG-----IGPRVLHSACFAAIG 288 + GL RG IG + + CF G Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFG 94
>DNC_PONPY (Q5NVC1) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 13/121 (10%) Frame = -3 Query: 629 YAGYAATLLRNLPAGVLS---YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGL 459 Y G A TL+ P L YSS ++L +A+ N +++LCG+ AG IS L Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVISKTL 233 Query: 458 TTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGLMGLSRGIGPRVLHS 309 T PLD+ K RL G + +R G + ++V+ +EG +G +G+ P +L + Sbjct: 234 TYPLDLFKKRLQVG-GFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292 Query: 308 A 306 A Sbjct: 293 A 293 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/137 (22%), Positives = 57/137 (41%), Gaps = 4/137 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 QILQ +G + G+ + ++ G + + SFE L S +CG L Sbjct: 68 QILQEEGPTAFWKGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGL 127 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIA----EEGLMGLSRGIGPRVL 315 A ++ P+DV++TR AQG V T+ + EG +G+ P ++ Sbjct: 128 AACMATLTVHPVDVLRTRF----AAQGEPKVYNTLCHAVGTMYRSEGPQVFYKGLAPTLI 183 Query: 314 HSACFAAIGYCAFETAR 264 +A + + + + + Sbjct: 184 AIFPYAGLQFSCYSSLK 200 Score = 33.1 bits (74), Expect = 0.78 Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 7/95 (7%) Frame = -3 Query: 536 KSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRL------MTRVGAQGS-RTVVGTM 378 K + N T + + G+++G ++ L +P DV+K R ++R ++ Sbjct: 7 KPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPNAKYHGILQAS 66 Query: 377 QEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 273 ++++ EEG +G P + S + A+ + +FE Sbjct: 67 RQILQEEGPTAFWKGHIPAQILSIGYGAVQFLSFE 101
>DNC_MACFA (Q5IS35) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 320 Score = 52.8 bits (125), Expect = 9e-07 Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 13/121 (10%) Frame = -3 Query: 629 YAGYAATLLRNLPAGVLS---YSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGL 459 Y G A TL+ P L YSS ++L +A+ N +++LCG+ AG IS L Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAMPAEGKKNENL-QNLLCGSGAGVISKTL 233 Query: 458 TTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGLMGLSRGIGPRVLHS 309 T PLD+ K RL G + +R G + ++V+ +EG +G +G+ P +L + Sbjct: 234 TYPLDLFKKRLQVG-GFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKA 292 Query: 308 A 306 A Sbjct: 293 A 293 Score = 43.5 bits (101), Expect = 6e-04 Identities = 31/137 (22%), Positives = 57/137 (41%), Gaps = 4/137 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 QILQ +G + G+ + ++ G + + SFE L S +CG L Sbjct: 68 QILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGL 127 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIA----EEGLMGLSRGIGPRVL 315 A + P+DV++TR AQG V T++ + EG +G+ P ++ Sbjct: 128 AACTATLTVHPVDVLRTRF----AAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLI 183 Query: 314 HSACFAAIGYCAFETAR 264 +A + + + + + Sbjct: 184 AIFPYAGLQFSCYSSLK 200 Score = 36.2 bits (82), Expect = 0.092 Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 7/95 (7%) Frame = -3 Query: 536 KSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-------VVGTM 378 K + N T + + G+++G ++ L +P DV+K R + R + Sbjct: 7 KPDGRNNTKLQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQAS 66 Query: 377 QEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 273 ++++ EEGL +G P + S + A+ + +FE Sbjct: 67 RQILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFE 101
>UCP3_BOVIN (O77792) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 52.4 bits (124), Expect = 1e-06 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 5/126 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G LY+G A L R + + ++ +K F K + + + +L G Sbjct: 65 ILTMVRTEGPRSLYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPK-GSDHSSIITRILAG 123 Query: 488 ALAGAISAGLTTPLDVVKTRLMT--RVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGP 324 GA++ P DVVK R G G+R GTM + + EEG+ GL +GI P Sbjct: 124 CTTGAMAVTCAQPTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGILP 183 Query: 323 RVLHSA 306 + +A Sbjct: 184 NITRNA 189 Score = 35.4 bits (80), Expect = 0.16 Identities = 30/137 (21%), Positives = 56/137 (40%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + RN +++ +K L + P V A Sbjct: 168 IAREEGVRGLWKGILPNITRNAIVNCGEMVTYDIIKEKLLDYHLLTDNFPCHFVSAFG-A 226 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M Q + M +++ +EG +G P L + Sbjct: 227 GFCATLVASPVDVVKTRYMNSPPGQ-YHSPFDCMLKMVTQEGPTAFYKGFTPSFLRLGSW 285 Query: 299 AAIGYCAFETARLMILK 249 + + +E + ++K Sbjct: 286 NVVMFVTYEQMKRALMK 302
>DNC_MOUSE (Q9DAM5) Mitochondrial deoxynucleotide carrier (Solute carrier| family 25 member 19) Length = 318 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/128 (28%), Positives = 61/128 (47%), Gaps = 12/128 (9%) Frame = -3 Query: 653 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA--LSKSNAPNLTPGESVLCGALA 480 +T+G F Y G T++ P L +S + LK L + +++LCG + Sbjct: 167 KTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNLKNLLCGCGS 226 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM----------QEVIAEEGLMGLSRGI 330 G IS T PLD++K RL G + +R+ G + Q+V+ EEG G +G+ Sbjct: 227 GVISKTFTYPLDLIKKRLQVG-GFEHARSAFGQVRSYRGLLDLTQQVLQEEGTRGFFKGL 285 Query: 329 GPRVLHSA 306 P ++ +A Sbjct: 286 SPSLMKAA 293 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/137 (21%), Positives = 58/137 (42%), Gaps = 4/137 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 QILQ +G + G+ + ++ G + + +FE L + +CG L Sbjct: 68 QILQEEGPRAFWKGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHFVCGGL 127 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVI----AEEGLMGLSRGIGPRVL 315 + + P+DV++TRL AQG + ++E I EG +G+ P V+ Sbjct: 128 SAGTATLTVHPVDVLRTRL----AAQGEPKIYNNLREAIRTMYKTEGPFVFYKGLTPTVI 183 Query: 314 HSACFAAIGYCAFETAR 264 +A + + + + + Sbjct: 184 AIFPYAGLQFSCYRSLK 200 Score = 36.6 bits (83), Expect = 0.070 Identities = 26/113 (23%), Positives = 55/113 (48%), Gaps = 7/113 (6%) Frame = -3 Query: 506 ESVLCGALAGAISAGLTTPLDVVKTRLMTRV----GAQGSRTVVGTMQ---EVIAEEGLM 348 E + G+++G ++ L +PLDV+K R ++ + + G Q +++ EEG Sbjct: 17 EVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPR 76 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAA 189 +G P + S + A+ + AFE ++ ++ L + +A + G++A Sbjct: 77 AFWKGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHFVCGGLSA 129
>TXTP_YEAST (P38152) Tricarboxylate transport protein (Citrate transport| protein) (CTP) Length = 299 Score = 51.6 bits (122), Expect = 2e-06 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 3/138 (2%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN---LTPGESVLCG 489 +++ GF GLY G +R + + +K +++P L+ G + L G Sbjct: 162 LVRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPKDKPLSSGLTFLVG 221 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 A +G ++ T PLD VKTR+ + + S T + + EEGL +G PR+ Sbjct: 222 AFSGIVTVYSTMPLDTVKTRMQSLDSTKYSST-MNCFATIFKEEGLKTFWKGATPRLGRL 280 Query: 308 ACFAAIGYCAFETARLMI 255 I + +E +M+ Sbjct: 281 VLSGGIVFTIYEKVLVML 298 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Frame = -3 Query: 539 SKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGTMQEVIA 363 SK+ ++ P S L G+LAGA A +T P + KTRL + ++ SR + + + Sbjct: 3 SKATKSDVDPLHSFLAGSLAGAAEACITYPFEFAKTRLQLIDKASKASRNPLVLIYKTAK 62 Query: 362 EEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILKS 246 +G+ + G ++ + A I + F+T + M+ S Sbjct: 63 TQGIGSIYVGCPAFIIGNTAKAGIRFLGFDTIKDMLRDS 101
>GHC1_PONPY (Q5RD81) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 51.6 bits (122), Expect = 2e-06 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA--LSKSNAPNLTPGESVLCGA 486 +L++ G GLY G ATLLR++P V+ + F L S+ +P S L G Sbjct: 177 LLRSRGIAGLYKGLGATLLRDVPLSVVYFPLFANLNQLGRPASEEKSPFYV---SFLAGC 233 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVL 315 +AG+ +A P DVVKTRL + T G + ++++ EG +G R L Sbjct: 234 VAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRAL 293 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/158 (21%), Positives = 71/158 (44%), Gaps = 27/158 (17%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++ ++++G+FG+Y G A L P + ++ ++ + LSK + LT + +L G Sbjct: 53 LIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFR-HQLSK-DGQKLTLLKEMLAG 110 Query: 488 ALAGAISAGLTTPLDVVKTRLMT---------------RVGAQGSR------------TV 390 AG +TTP++++K +L ++ AQG T Sbjct: 111 CGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTA 170 Query: 389 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 276 + ++++ G+ GL +G+G +L + + + F Sbjct: 171 IQLTRDLLRSRGIAGLYKGLGATLLRDVPLSVVYFPLF 208 Score = 32.0 bits (71), Expect = 1.7 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRG 333 G +AG I P+D+ KTRL + Q T + + + I EG G+ RG Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYTSMSDCLIKTIRSEGYFGMYRG 68
>GHC1_HUMAN (Q9H936) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 51.2 bits (121), Expect = 3e-06 Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 5/120 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA--LSKSNAPNLTPGESVLCGA 486 +L++ G GLY G ATLLR++P V+ + F L S+ +P S L G Sbjct: 177 LLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYV---SFLAGC 233 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRVL 315 +AG+ +A P DVVKTRL + T G + ++++ EG +G R L Sbjct: 234 VAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRAL 293 Score = 46.2 bits (108), Expect = 9e-05 Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 27/158 (17%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++ ++++G+FG+Y G A L P + ++ ++ + LSK + LT + +L G Sbjct: 53 LIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFR-HQLSK-DGQKLTLLKEMLAG 110 Query: 488 ALAGAISAGLTTPLDVVKTRLMTR---------VGAQGSRTVVGTMQ------------- 375 AG +TTP++++K +L + AQG + G Q Sbjct: 111 CGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTA 170 Query: 374 -----EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 276 +++ G+ GL +G+G +L F+ + + F Sbjct: 171 TQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLF 208 Score = 31.2 bits (69), Expect = 2.9 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG-TMQEVIAEEGLMGLSRG 333 G +AG I P+D+ KTRL + Q T + + + + EG G+ RG Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRG 68
>UCP1_HUMAN (P25874) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 50.8 bits (120), Expect = 4e-06 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF-ALSKSNAPNLTPGESVLCGAL 483 +++T+G LY+G A L R + + L ++ ++ F K AP+L G +L G Sbjct: 65 VVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSL--GSKILAGLT 122 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVL 315 G ++ + P +VVK RL + G + GT + EGL GL +G P ++ Sbjct: 123 TGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLM 182 Query: 314 HS 309 S Sbjct: 183 RS 184 Score = 45.4 bits (106), Expect = 2e-04 Identities = 33/138 (23%), Positives = 61/138 (44%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+G GL+ G L+R++ +++ +K + + + P V +A Sbjct: 164 IATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLV-SALIA 222 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + +++P+DVVKTR + Q ++V +V EG +G+ P L + Sbjct: 223 GFCATAMSSPVDVVKTRFINSPPGQ-YKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSW 281 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + + KS Sbjct: 282 NVIMFVCFEQLKRELSKS 299
>DIC_HUMAN (Q9UBX3) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/145 (26%), Positives = 66/145 (45%), Gaps = 5/145 (3%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 L++++TDG LY+G +A+L R + + ++ +E ++ S P L E VL G+ Sbjct: 49 LRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGP-LPFHEKVLLGS 107 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVG-AQGSRT----VVGTMQEVIAEEGLMGLSRGIGPR 321 ++G + TP D+V R+ V QG R + + V EEGL L G Sbjct: 108 VSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMA 167 Query: 320 VLHSACFAAIGYCAFETARLMILKS 246 A ++ A+ ++L + Sbjct: 168 SSRGALVTVGQLSCYDQAKQLVLST 192 Score = 30.0 bits (66), Expect = 6.6 Identities = 24/86 (27%), Positives = 36/86 (41%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L ++ + +G L++G R V S ++ K LS + V Sbjct: 148 LYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFV-AS 206 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVG 411 +AG + L PLDV+KTRLM G Sbjct: 207 FIAGGCATFLCQPLDVLKTRLMNSKG 232
>FLX1_YEAST (P40464) Mitochondrial FAD carrier protein FLX1| Length = 311 Score = 50.4 bits (119), Expect = 5e-06 Identities = 33/137 (24%), Positives = 66/137 (48%), Gaps = 4/137 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAP----NLTPGESVL 495 Q+L+TDGF GL+ G L + G L ++ ++ LK L + +LT E++ Sbjct: 173 QLLRTDGFQGLWKGLVPALF-GVSQGALYFAVYDTLKQRKLRRKRENGLDIHLTNLETIE 231 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 +L +S L P ++K+ L + + + ++ +IA +G +GL +G+ ++ Sbjct: 232 ITSLGKMVSVTLVYPFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGLYKGLSANLV 291 Query: 314 HSACFAAIGYCAFETAR 264 + I +C +E + Sbjct: 292 RAIPSTCITFCVYENLK 308 Score = 44.3 bits (103), Expect = 3e-04 Identities = 29/88 (32%), Positives = 51/88 (57%), Gaps = 2/88 (2%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLM-TRVGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGPRV 318 GA +G ++A LT P+ V+KTR+M T GAQG+ T + +Q+++ +G GL +G+ P Sbjct: 132 GASSGLMTAILTNPIWVIKTRIMSTSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGLVP-A 190 Query: 317 LHSACFAAIGYCAFETARLMILKSYLES 234 L A+ + ++T + L+ E+ Sbjct: 191 LFGVSQGALYFAVYDTLKQRKLRRKREN 218
>UCP3_CANFA (Q9N2I9) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 311 Score = 50.1 bits (118), Expect = 6e-06 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 6/149 (4%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPGESVLC 492 +L +++T+G Y G A L R + + ++ +K F K S+ ++T +L Sbjct: 65 ILTMVRTEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSSITT--RILA 122 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTM---QEVIAEEGLMGLSRGIG 327 G GA++ P DVVK R + GA +R GTM + + EEG+ GL +G Sbjct: 123 GCTTGAMAVSCAQPTDVVKVRFQASIHLGAGSNRKYSGTMDAYRTIAREEGVRGLWKGTL 182 Query: 326 PRVLHSACFAAIGYCAFETARLMILKSYL 240 P + +A ++ + +L +L Sbjct: 183 PNITRNAIVNCAEMVTYDIIKEKLLDYHL 211 Score = 36.2 bits (82), Expect = 0.092 Identities = 29/137 (21%), Positives = 57/137 (41%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + RN +++ +K L + P + A Sbjct: 168 IAREEGVRGLWKGTLPNITRNAIVNCAEMVTYDIIKEKLLDYHLLTDNFPCHLISAFG-A 226 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M Q + + M +++ +EG +G P L + Sbjct: 227 GFCATVVASPVDVVKTRYMNSPPGQYC-SPLDCMLKMVTQEGPTAFYKGFTPSFLRLGTW 285 Query: 299 AAIGYCAFETARLMILK 249 + + +E + ++K Sbjct: 286 NVVMFVTYEQLKRALMK 302
>ADT_DROME (Q26365) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) (Stress sensitive B protein) Length = 312 Score = 50.1 bits (118), Expect = 6e-06 Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 6/143 (4%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYS-SFEYLKAF--ALSKSNAPNLTPGESVL 495 ++I + GF + G A ++R P L+++ +Y + F + K+ ++ Sbjct: 74 IRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLA 133 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG---TMQEVIAEEGLMGLSRGIGP 324 G AGA S PLD +TRL G G R G + ++ +G++GL RG G Sbjct: 134 SGGAAGATSLCFVYPLDFARTRLAADTGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFGV 193 Query: 323 RVLHSACFAAIGYCAFETARLMI 255 V + A + ++TAR M+ Sbjct: 194 SVQGIIIYRAAYFGFYDTARGML 216 Score = 31.6 bits (70), Expect = 2.3 Identities = 22/96 (22%), Positives = 47/96 (48%), Gaps = 3/96 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I ++DG GLY G+ ++ G++ Y + Y + ++ P+ + Sbjct: 175 LTKIFKSDGIVGLYRGFGVSV-----QGIIIYRA-AYFGFYDTARGMLPDPKNTPIYISW 228 Query: 488 ALAGAIS--AGLTT-PLDVVKTRLMTRVGAQGSRTV 390 A+A ++ AG+ + P D V+ R+M + G + + + Sbjct: 229 AIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVI 264
>MFTC_MOUSE (Q8BMG8) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 316 Score = 49.7 bits (117), Expect = 8e-06 Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 6/142 (4%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L I + DG GLY G + + L + + +K++ ++ A L P E ++ Sbjct: 69 LATIWKVDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYK-TEGRAEQLEPLEYLVSA 127 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGS------RTVVGTMQEVIAEEGLMGLSRGIG 327 A AGA++ +T PL V KTRLM + G S + + + ++ EG+ GL +G Sbjct: 128 AEAGAMTLCITNPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGLYKGFV 187 Query: 326 PRVLHSACFAAIGYCAFETARL 261 P L A+ + A+E +L Sbjct: 188 PG-LFGTSHGALQFMAYELLKL 208 Score = 43.5 bits (101), Expect = 6e-04 Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 3/135 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA---LSKSNAPNLTPGESV 498 L++I + +G GLY G+ L G L + ++E LK +++ L+ E + Sbjct: 170 LVKIYKYEGVRGLYKGFVPGLF-GTSHGALQFMAYELLKLKYNKHINRLPEAQLSTAEYI 228 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 318 AL+ + T P VV+ RL + + G T V T + +EG+ G +GI P + Sbjct: 229 SVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVTDVIT--KTWRKEGIGGFYKGIAPNL 286 Query: 317 LHSACFAAIGYCAFE 273 + I + +E Sbjct: 287 IRVTPACCITFVVYE 301
>PM34_HUMAN (O43808) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 49.3 bits (116), Expect = 1e-05 Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 8/152 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 LL+I++ +G Y G+ + + + + +F LKA + ++ T G+ ++ G Sbjct: 52 LLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKALWVKGQHS---TTGKDLVVG 108 Query: 488 ALAGAISAGLTTPLDVVKTRLMTR--------VGAQGSRTVVGTMQEVIAEEGLMGLSRG 333 +AG ++ LTTPL VV TRL + + + ++ ++I +EG+ L G Sbjct: 109 FVAGVVNVLLTTPLWVVNTRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNG 168 Query: 332 IGPRVLHSACFAAIGYCAFETARLMILKSYLE 237 P +L AI + +E + +LK ++ Sbjct: 169 TFPSLL-LVFNPAIQFMFYEGLKRQLLKKRMK 199 Score = 32.0 bits (71), Expect = 1.7 Identities = 21/83 (25%), Positives = 38/83 (45%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 318 + GA+ + + PLD + RL + S+T + E+I EEGL+ RG P + Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRK-SKTTHMVLLEIIKEEGLLAPYRGWFPVI 72 Query: 317 LHSACFAAIGYCAFETARLMILK 249 C + + F + + + +K Sbjct: 73 SSLCCSNFVYFYTFNSLKALWVK 95
>MFRN1_HUMAN (Q9NYZ2) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) (Mitochondria solute carrier protein) Length = 347 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 2/83 (2%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLT--PGESVLCGA 486 + +T+G Y Y L N+P + + ++E+L+ + P+ T P ++ G Sbjct: 188 VWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQ-----EQVNPHRTYNPQSHIISGG 242 Query: 485 LAGAISAGLTTPLDVVKTRLMTR 417 LAGA++A TTPLDV KT L T+ Sbjct: 243 LAGALAAAATTPLDVCKTLLNTQ 265 Score = 32.0 bits (71), Expect = 1.7 Identities = 17/78 (21%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 318 GA+AG + + P+D VKTR+ + ++ ++ G +++++ EG RG+ + Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMI 111 Query: 317 LHSACFAAIGYCAFETAR 264 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>GHC1_MOUSE (Q9D6M3) Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+)| symporter 1) (Solute carrier family 25 member 22) Length = 323 Score = 48.9 bits (115), Expect = 1e-05 Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP-GESVLCGAL 483 +L+ G GLY G ATLLR++P ++ + F L L + ++ +P S L G + Sbjct: 177 LLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLN--QLGRPSSEEKSPFYVSFLAGCV 234 Query: 482 AGAISAGLTTPLDVVKTRLMT 420 AG+ +A P DVVKTRL + Sbjct: 235 AGSAAAVAVNPCDVVKTRLQS 255 Score = 46.6 bits (109), Expect = 7e-05 Identities = 35/158 (22%), Positives = 71/158 (44%), Gaps = 27/158 (17%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++ ++++G+FG+Y G A L P + ++ ++ + LSK + LT + +L G Sbjct: 53 LIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFR-HQLSK-DGQKLTLPKEMLAG 110 Query: 488 ALAGAISAGLTTPLDVVKTRL---------------MTRVGAQGSR------------TV 390 AG +TTP++++K +L ++ AQG T Sbjct: 111 CGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQAQLSAQGGAQPSVEAPAPPRPTA 170 Query: 389 VGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAF 276 ++++ G+ GL +G+G +L F+ + + F Sbjct: 171 TQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLF 208 Score = 30.4 bits (67), Expect = 5.0 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGS-RTVVGTMQEVIAEEGLMGLSRG 333 G +AG I P+D+ KTRL + Q ++ + + I EG G+ RG Sbjct: 15 GGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRG 68
>ODC_MOUSE (Q8BZ09) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 3/113 (2%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I +T+G FG Y G +L P + +S+FE K F S +P LT ++ G + Sbjct: 62 IFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLT---FLIAGLGS 118 Query: 479 GAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGTMQEVIAEEGL--MGLSRGI 330 G A + P +VVK L + R + + +++I +EGL GL++G+ Sbjct: 119 GLTEAVVVNPFEVVKVGLQVNRNLFKEQPSTFAYARQIIKKEGLGFQGLNKGL 171 Score = 48.9 bits (115), Expect = 1e-05 Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Frame = -3 Query: 542 LSKSNAPNL-TPGESVLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQ 375 +S SN L V G AG + L PLDVVKTR + Q RTV G+ Q Sbjct: 1 MSASNVSLLHETSRQVAAGGSAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYRTVRGSFQ 60 Query: 374 EVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 273 + EGL G +GI P +L A+ + FE Sbjct: 61 MIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFE 94 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 3/113 (2%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 GF GL G ATL R+ ++ + + +K + S P L G ++G + + Sbjct: 163 GFQGLNKGLTATLGRHGIFNMVYFGFYHNVKNI-IPSSKDPTLEFLRKFGIGFVSGTMGS 221 Query: 464 GLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 P DV K+R+ G R+ TM+ + EEG++ L +G+ P+V+ Sbjct: 222 VFNIPFDVAKSRIQGPQPVPGEIKYRSCFKTMEMIYREEGILALYKGLVPKVM 274
>DIC_MOUSE (Q9QZD8) Mitochondrial dicarboxylate carrier (Solute carrier family| 25 member 10) Length = 287 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 5/145 (3%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 LQ+++TDGF LY G +A+L R + + ++ +E ++ + S P L VL G Sbjct: 48 LQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGP-LPFYNKVLLGG 106 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGLMGLSRGIGPR 321 ++G + TP D+V R+ + S+ + + V EE L L G Sbjct: 107 ISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSGATMA 166 Query: 320 VLHSACFAAIGYCAFETARLMILKS 246 A ++ A+ ++L + Sbjct: 167 SSRGALVTVGQLSCYDQAKQLVLST 191
>UCP1_CANFA (Q9GMZ1) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 309 Score = 48.5 bits (114), Expect = 2e-05 Identities = 35/138 (25%), Positives = 63/138 (45%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+G GL+ G L+RN+ +++ +K + + P L +A Sbjct: 166 IATTEGLTGLWKGTTPNLMRNVIINCTELVTYDLMKEALVKNHLLADDLPCH-FLSALVA 224 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L++P+DVVKTR + V Q + +V ++ +EG + +G P L + Sbjct: 225 GFCTTVLSSPVDVVKTRFVNSVPEQYT-SVPNCAMTMLTKEGPLAFFKGFVPSFLRLGSW 283 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + ++KS Sbjct: 284 NVIMFVCFEQLKRELMKS 301 Score = 35.8 bits (81), Expect = 0.12 Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 9/99 (9%) Frame = -3 Query: 533 SNAPNLTPGESVLCGALAGA--ISAGLTTPLDVVKTRLMTRVGAQGS-------RTVVGT 381 S+AP P SV A AGA ++ +T PLD K RL + QG R V+GT Sbjct: 7 SDAP---PTLSVRIAAAAGAACLADMITFPLDTAKVRLQIQGEGQGQPPRAPRYRGVLGT 63 Query: 380 MQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETAR 264 + + EGL L G+ + FA++ +++ R Sbjct: 64 VATLARTEGLQKLYSGLPAGLQRQVGFASLRIGLYDSVR 102
>MCATL_MOUSE (Q8BL03) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 306 Score = 48.5 bits (114), Expect = 2e-05 Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 8/134 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L+QI + +G G+ G +TLLR P+ + + +++ + A+ L + +L G Sbjct: 138 LVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVMTR-AMGCEPGDRLLVPKLLLAG 196 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGPRV 318 +G S T P+DVVK+RL G QG+ R +V M++ EG +RG+ + Sbjct: 197 GTSGITSWLSTYPMDVVKSRLQAD-GLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTL 255 Query: 317 L-----HSACFAAI 291 L ++A FA + Sbjct: 256 LRAFPVNAATFATV 269 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 4/114 (3%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYS-SFEYLKAFALSKSNAPNLTPGESVLCGAL 483 I++ + GLY G + L+ L + L+A +P L GA Sbjct: 49 IIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQD-------SPLNQFLAGAA 101 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQ---EVIAEEGLMGLSRGI 330 AGAI + P+++ KTRL + +RT G++ ++ EGL G++RG+ Sbjct: 102 AGAIQCVICCPMELAKTRLQLQ-AVGPARTYKGSLDCLVQIYRHEGLRGINRGM 154 Score = 31.6 bits (70), Expect = 2.3 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-RTVVGTMQEVIAEEGLMGLSRGIG 327 L G G + P D+VK RL + + R + Q +I +E ++GL +G+G Sbjct: 6 LAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLG 63
>YIA6_YEAST (P40556) Putative mitochondrial carrier YIL006W| Length = 373 Score = 48.1 bits (113), Expect = 2e-05 Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Frame = -3 Query: 572 SSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTR-----LMTRVGA 408 SS E + L K P + + L GA AG +S PLDV KTR L TR Sbjct: 57 SSTESIIGTTLRKKWVPLSSTQITALSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFEN 116 Query: 407 QGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 R ++GT+ ++ +EG GL +G+ P VL Sbjct: 117 PYYRGIMGTLSTIVRDEGPRGLYKGLVPIVL 147 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 4/122 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L I++ +G GLY G +L P ++ +S +E+ K F P Sbjct: 126 LSTIVRDEGPRGLYKGLVPIVLGYFPTWMIYFSVYEFSKKFF--HGIFPQFDFVAQSCAA 183 Query: 488 ALAGAISAGLTTPLDVVKTRLM--TRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LT P+ VVKTRLM + +G + + +++ +EG L G+ P Sbjct: 184 ITAGAASTTLTNPIWVVKTRLMLQSNLGEHPTHYKGTFDAFRKLFYQEGFKALYAGLVPS 243 Query: 320 VL 315 +L Sbjct: 244 LL 245 Score = 38.5 bits (88), Expect = 0.018 Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 5/138 (3%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA--FALSKSNAPN-LTPGESVLC 492 ++ +GF LYAG +LL L + + +E LK S+ N N + ++ Sbjct: 226 KLFYQEGFKALYAGLVPSLL-GLFHVAIHFPIYEDLKVRFHCYSRENNTNSINLQRLIMA 284 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPRV 318 +++ I++ +T P ++++TR+ + S R + ++ A+EGL G G + Sbjct: 285 SSVSKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGFYSGFTTNL 344 Query: 317 LHSACFAAIGYCAFETAR 264 + + +AI +FE R Sbjct: 345 VRTIPASAITLVSFEYFR 362
>PM34_MOUSE (O70579) Peroxisomal membrane protein PMP34 (34 kDa peroxisomal| membrane protein) (Solute carrier family 25 member 17) Length = 307 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/153 (24%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 LL+I++ +G Y G+ + + + + +F LKA + + + G+ ++ G Sbjct: 52 LLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLKAVWVKGQRS---STGKDLVVG 108 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQ---------GSRTVVGTMQEVIAEEGLMGLSR 336 +AG ++ LTTPL VV TRL + GA+ + ++ ++I +EG++ L Sbjct: 109 FVAGVVNVLLTTPLWVVNTRLKLQ-GAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWN 167 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMILKSYLE 237 G P +L AI + +E + +LK ++ Sbjct: 168 GTFPSLL-LVFNPAIQFMFYEGLKRQLLKKRMK 199 Score = 33.1 bits (74), Expect = 0.78 Identities = 22/88 (25%), Positives = 39/88 (44%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 318 + GA+ + + PLD + RL + S+T + E+I EEGL+ RG P + Sbjct: 14 VAGAVGSVTAMTVFFPLDTARLRLQVDEKRK-SKTTHAVLLEIIKEEGLLAPYRGWFPVI 72 Query: 317 LHSACFAAIGYCAFETARLMILKSYLES 234 C + + F + + + +K S Sbjct: 73 SSLCCSNFVYFYTFNSLKAVWVKGQRSS 100
>UCP4_HUMAN (O95847) Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier| family 25 member 27) Length = 323 Score = 48.1 bits (113), Expect = 2e-05 Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 11/154 (7%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGA 486 L I++ +GF L+ G + R++ ++E+L+ KS + +SV+ G Sbjct: 76 LGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGM 135 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG----------TMQEVIAEEGLMGLSR 336 +AG I L P D+VK ++ +G R + G +++AE G+ GL Sbjct: 136 MAGVIGQFLANPTDLVKVQMQ----MEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWA 191 Query: 335 GIGPRVLHSACFAAIGYCAFETAR-LMILKSYLE 237 G P + +A ++T + ++L + LE Sbjct: 192 GWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLE 225 Score = 45.4 bits (106), Expect = 2e-04 Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN--LTPGESVLCG 489 +IL G GL+AG+ + R + ++++ +K + + + + +T G S LC Sbjct: 179 KILAEGGIRGLWAGWVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCS 238 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVV-----GTMQEVIAEEGLMGLSRGIGP 324 L +I L TP DV+K+R+M + + R ++ + + + EG M L +G P Sbjct: 239 GLVASI---LGTPADVIKSRIMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLP 295 Query: 323 RVLHSACFAAIGYCAFETARLM 258 L ++ + + +E R M Sbjct: 296 SWLRMTPWSMVFWLTYEKIREM 317 Score = 31.6 bits (70), Expect = 2.3 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 12/93 (12%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRL-------MTRVG-----AQGSRTVVGTMQEVIAEEG 354 L A ++ T PLD+ KTRL + R+G + R +V T +I EEG Sbjct: 24 LLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEEG 83 Query: 353 LMGLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 + L +G+ P + ++ +E R ++ Sbjct: 84 FLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVV 116 Score = 29.6 bits (65), Expect = 8.6 Identities = 12/39 (30%), Positives = 24/39 (61%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK 552 L+Q +Q +GF LY G+ + LR P ++ + ++E ++ Sbjct: 277 LIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIR 315
>ODC1_YEAST (Q03028) Mitochondrial 2-oxodicarboxylate carrier 1| Length = 310 Score = 47.4 bits (111), Expect = 4e-05 Identities = 31/115 (26%), Positives = 58/115 (50%), Gaps = 2/115 (1%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN--LTPGESVL 495 L +I++ +GF LY G + +L P + +S + + F PN +T ++ Sbjct: 68 LTKIVKKEGFSHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIFPTPNGEMTQKIAIY 127 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 GA AGA+ A + P ++VK RL V +Q +T + ++ + + G++ L G+ Sbjct: 128 SGASAGAVEAFVVAPFELVKIRLQD-VNSQ-FKTPIEVVKNSVVKGGVLSLFNGL 180 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 3/116 (2%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNL--PAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAI 471 G L+ G AT+ R++ AG F+ K +K++ ++ GA+ G + Sbjct: 172 GVLSLFNGLEATIWRHVLWNAGYFGII-FQIRKLLPAAKTSTEKTR--NDLIAGAIGGTV 228 Query: 470 SAGLTTPLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 L TP DVVK+R+ G + + ++ V EEG L +G P+V+ A Sbjct: 229 GCLLNTPFDVVKSRIQRSSGPLRKYNWSLPSVLLVYREEGFKALYKGFAPKVMRLA 284 Score = 37.4 bits (85), Expect = 0.041 Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 13/96 (13%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGT-------------MQEVIAEEGL 351 GA+AG + PLDVVKTR+ +V +G VV + +++ +EG Sbjct: 18 GAIAGVSELLVMYPLDVVKTRMQLQVTTKGHPAVVAAKAAVDHYTGVMDCLTKIVKKEGF 77 Query: 350 MGLSRGIGPRVLHSACFAAIGYCAFETARLMILKSY 243 L +GI +L A AI + +T + K + Sbjct: 78 SHLYKGITSPILMEAPKRAIKFSGNDTFQTFYKKIF 113
>ADT3_YEAST (P18238) ADP,ATP carrier protein 3 (ADP/ATP translocase 3) (Adenine| nucleotide translocator 3) (ANT 3) Length = 307 Score = 47.4 bits (111), Expect = 4e-05 Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 4/126 (3%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L++DG GLY G+ +++ + L + F+ LK L+ S G + L Sbjct: 170 LKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGS-----LDGSFLASFLLGW 224 Query: 476 AISAGLTT---PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 ++ G +T PLD V+ R+M G A + +++++A EG+ L +G G +L S Sbjct: 225 VVTTGASTCSYPLDTVRRRMMMTSGQAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRS 284 Query: 308 ACFAAI 291 A + Sbjct: 285 VAGAGV 290 Score = 44.7 bits (104), Expect = 3e-04 Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 7/144 (4%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGALAGAI 471 +G + G A ++R P L+++ + +K F K ++ G AGA+ Sbjct: 70 EGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKEEGYGKWFAGNLASGGAAGAL 129 Query: 470 SAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 S LD +TRL + GA+ + ++ + +G+ GL RG P V+ Sbjct: 130 SLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGI 189 Query: 308 ACFAAIGYCAFETARLMILKSYLE 237 + + + F++ + ++L L+ Sbjct: 190 VVYRGLYFGMFDSLKPLVLTGSLD 213
>OAC1_YEAST (P32332) Mitochondrial oxaloacetate transport protein| (Mitochondrial carrier protein PMT) Length = 324 Score = 47.4 bits (111), Expect = 4e-05 Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 12/152 (7%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP------GESV 498 I + +G GL G A + + +E +++ +L++ P+ P G +V Sbjct: 74 IFKNEGIKGLQKGLNAAYIYQIGLNGSRLGFYEPIRS-SLNQLFFPDQEPHKVQSVGVNV 132 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMT-----RVGAQGSRT-VVGTMQEVIAEEGLMGLSR 336 GA +G I A + +PL +VKTRL + ++G Q T V + + EG+ GL R Sbjct: 133 FSGAASGIIGAVIGSPLFLVKTRLQSYSEFIKIGEQTHYTGVWNGLVTIFKTEGVKGLFR 192 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMILKSYL 240 GI +L + +++ + TA+ +++K+ L Sbjct: 193 GIDAAILRTGAGSSVQLPIYNTAKNILVKNDL 224 Score = 33.5 bits (75), Expect = 0.59 Identities = 28/121 (23%), Positives = 52/121 (42%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L+ I +T+G GL+ G A +LR + + K L K++ P + Sbjct: 178 LVTIFKTEGVKGLFRGIDAAILRTGAGSSVQLPIYNTAKNI-LVKNDLMKDGPALHLTAS 236 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 ++G A + P DV+ TR+ + G + + + + + EG+ L +G +V Sbjct: 237 TISGLGVAVVMNPWDVILTRIYNQKG-DLYKGPIDCLVKTVRIEGVTALYKGFAAQVFRI 295 Query: 308 A 306 A Sbjct: 296 A 296
>UCP3_PIG (O97649) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 308 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 6/149 (4%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPGESVLC 492 +L +++ +G Y G A L R + + ++ +K K S+ ++T +L Sbjct: 62 ILTMVRNEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDHSSITT--RILA 119 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRV--GAQGSRTVVGTM---QEVIAEEGLMGLSRGIG 327 G GA++ P DVVK R + G + +R GTM + + EEG+ GL +GI Sbjct: 120 GCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGIL 179 Query: 326 PRVLHSACFAAIGYCAFETARLMILKSYL 240 P + +A ++ + +L +L Sbjct: 180 PNITRNAIVNCAEMVTYDVIKEKVLDYHL 208 Score = 38.9 bits (89), Expect = 0.014 Identities = 30/137 (21%), Positives = 58/137 (42%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G + RN +++ +K L + P V A Sbjct: 165 IAREEGVRGLWKGILPNITRNAIVNCAEMVTYDVIKEKVLDYHLLTDNLPCHFVSAFG-A 223 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M Q + + M +++ +EG +G P L + Sbjct: 224 GFCATVVASPVDVVKTRYMNSPPGQ-YQNPLDCMLKMVTQEGPTAFYKGFTPSFLRLGSW 282 Query: 299 AAIGYCAFETARLMILK 249 + + ++E + ++K Sbjct: 283 NVVMFVSYEQLKRALMK 299
>ADT2_ANOGA (Q7PQV7) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 300 Score = 47.0 bits (110), Expect = 5e-05 Identities = 38/144 (26%), Positives = 66/144 (45%), Gaps = 7/144 (4%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYS-SFEYLKAFALSKSNAPNLTPG--ESVL 495 ++I + GF + G A ++R P L+++ +Y + F T ++ Sbjct: 61 VRIPREQGFSAFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFTRYFIGNLA 120 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVG----AQGSRTVVGTMQEVIAEEGLMGLSRGIG 327 G +AGA S PLD +TRL VG A+ + + + ++ +GL+GL RG G Sbjct: 121 SGGMAGATSLCFVYPLDFARTRLAADVGKGAEAREFKGLGDCISKIFKTDGLVGLYRGFG 180 Query: 326 PRVLHSACFAAIGYCAFETARLMI 255 V + A + ++TAR M+ Sbjct: 181 VSVQGIIIYRAAYFGFYDTARGML 204
>TXTP_HUMAN (P53007) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 47.0 bits (110), Expect = 5e-05 Identities = 35/130 (26%), Positives = 60/130 (46%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 +I++ G G Y G AT+L+ + + L+ + + + P + + GA+ Sbjct: 170 EIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAI 229 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AGA S TPLDV+KTR M + A R +++ +EGL +G PR+ Sbjct: 230 AGAASVFGNTPLDVIKTR-MQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCL 288 Query: 302 FAAIGYCAFE 273 AI + ++ Sbjct: 289 DVAIVFVIYD 298 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 3/136 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 Q +++ G GLY G ++ L ++P + + FE+L + T G +LCG Sbjct: 73 QTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRG--LLCGLG 130 Query: 482 AGAISAGLTT-PLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 AG A + P++ +K + + + R ++E++ E+GL G +G+ VL Sbjct: 131 AGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLK 190 Query: 311 SACFAAIGYCAFETAR 264 AI + + R Sbjct: 191 QGSNQAIRFFVMTSLR 206 Score = 45.4 bits (106), Expect = 2e-04 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Frame = -3 Query: 557 LKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 384 L A A + A PG+++L G LAG I +T P + VKT+L R R + Sbjct: 10 LAAAAPASGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGD 69 Query: 383 TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 273 +++ + G++GL RG+ + S AA+ + FE Sbjct: 70 CVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFE 106
>TXTP_BOVIN (P79110) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 47.0 bits (110), Expect = 5e-05 Identities = 35/130 (26%), Positives = 60/130 (46%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 +I++ G G Y G AT+L+ + + L+ + + + P + + GA+ Sbjct: 170 EIVREQGLKGTYQGLTATVLKQGSNQGIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAI 229 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AGA S TPLDV+KTR M + A R + +++ EGL +G PR+ Sbjct: 230 AGAASVFGNTPLDVIKTR-MQGLEAHKYRNTLDCGLQILRNEGLKAFYKGTVPRLGRVCL 288 Query: 302 FAAIGYCAFE 273 AI + ++ Sbjct: 289 DVAIVFIIYD 298 Score = 45.4 bits (106), Expect = 2e-04 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 2/82 (2%) Frame = -3 Query: 512 PGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLS 339 PG+++L G LAG I +T P + VKT+L R R + +++ + GL+GL Sbjct: 25 PGKAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGLLGLY 84 Query: 338 RGIGPRVLHSACFAAIGYCAFE 273 RG+ + S AA+ + FE Sbjct: 85 RGLSSLLYGSIPKAAVRFGTFE 106 Score = 45.1 bits (105), Expect = 2e-04 Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 3/136 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 Q +++ G GLY G ++ L ++P + + +FE+L + T G +LCG Sbjct: 73 QTVRSHGLLGLYRGLSSLLYGSIPKAAVRFGTFEFLSNHMRDAQGRLDSTRG--LLCGLG 130 Query: 482 AGAISAGLTT-PLDVVKTRLM--TRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 AG A + P++ +K + + + R ++E++ E+GL G +G+ VL Sbjct: 131 AGVPEAVVVVCPMETIKVKFIHDQTSASPKYRGFFHGVREIVREQGLKGTYQGLTATVLK 190 Query: 311 SACFAAIGYCAFETAR 264 I + + R Sbjct: 191 QGSNQGIRFFVMTSLR 206
>ODC_HUMAN (Q9BQT8) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 46.6 bits (109), Expect = 7e-05 Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 9/144 (6%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I Q +G FG Y G +L P + + +FE K S +P LT + G + Sbjct: 63 IFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALT---FAIAGLGS 119 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSR-------TVVGTMQEVIAEE--GLMGLSRGIG 327 G A + P +VVK VG Q +R + VG +++I +E GL GL++G+ Sbjct: 120 GLTEAIVVNPFEVVK------VGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLT 173 Query: 326 PRVLHSACFAAIGYCAFETARLMI 255 + F + + + + MI Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKNMI 197 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = -3 Query: 662 QILQTDGFF--GLYAGYAATLLRNLPAGVLS--YSSFEYLKAFALSKSNAPNLTPGESVL 495 QI++ +G+ GL G ATL R+ GV + Y F Y + + P L Sbjct: 156 QIIKKEGWGLQGLNKGLTATLGRH---GVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFG 212 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGP 324 G L+G I++ + P DV K+R+ G RT TM V EEG++ L +G+ P Sbjct: 213 IGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLP 272 Query: 323 RVLHSACFAAIGYCAFE 273 +++ A+ +E Sbjct: 273 KIMRLGPGGAVMLLVYE 289 Score = 40.8 bits (94), Expect = 0.004 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 ++ G AG + L PLDVVKTR + +++V + + + EGL G +GI Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGI 76 Query: 329 GPRVLHSACFAAIGYCAFETARLMI 255 P +L A+ + FE + ++ Sbjct: 77 LPPILAETPKRAVKFFTFEQYKKLL 101
>TXTP_RAT (P32089) Tricarboxylate transport protein, mitochondrial precursor| (Citrate transport protein) (CTP) (Tricarboxylate carrier protein) (Solute carrier family 25 member 1) Length = 311 Score = 46.6 bits (109), Expect = 7e-05 Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 2/97 (2%) Frame = -3 Query: 557 LKAFALSKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--TRVGAQGSRTVVG 384 L A A A PG+++L G LAG I +T P + VKT+L R R + Sbjct: 10 LTAAAPGSGKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGD 69 Query: 383 TMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFE 273 +++ + G++GL RG+ + S AA+ + FE Sbjct: 70 CVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFE 106 Score = 45.1 bits (105), Expect = 2e-04 Identities = 34/130 (26%), Positives = 59/130 (45%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 +I++ G G Y G AT+L+ + + L+ + + + P + + GA+ Sbjct: 170 EIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYQGDNPNKPMNPLITGVFGAV 229 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AGA S TPLDV+KTR M + A R + +++ EG +G PR+ Sbjct: 230 AGAASVFGNTPLDVIKTR-MQGLEAHKYRNTLDCGVQILKNEGPKAFYKGTVPRLGRVCL 288 Query: 302 FAAIGYCAFE 273 AI + ++ Sbjct: 289 DVAIVFVIYD 298 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 3/136 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGAL 483 Q +++ G GLY G ++ L ++P + + FE+L + L +LCG Sbjct: 73 QTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNH--MRDAQGRLDSRRGLLCGLG 130 Query: 482 AGAISAGLTT-PLDVVKTRLMTRVGAQGS--RTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 AG A + P++ VK + + + R ++E++ E+GL G +G+ VL Sbjct: 131 AGVAEAVVVVCPMETVKVKFIHDQTSSNPKYRGFFHGVREIVREQGLKGTYQGLTATVLK 190 Query: 311 SACFAAIGYCAFETAR 264 AI + + R Sbjct: 191 QGSNQAIRFFVMTSLR 206
>ODC_RAT (Q99JD3) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 298 Score = 46.6 bits (109), Expect = 7e-05 Identities = 35/115 (30%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGV--LSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAI 471 GF GL G+ ATL R+ G+ ++Y F Y + S P L G ++G + Sbjct: 163 GFQGLNKGFTATLGRH---GIFNMTYFGFYYNVKDNIPSSKDPTLEFLRKFGIGFVSGTV 219 Query: 470 SAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 + P DV K+R+ G R TM+ V EEG++ L +G+ P+V+ Sbjct: 220 GSVFNIPFDVAKSRIQGPQPVPGEIKYRGCFKTMETVYREEGILALYKGLLPKVM 274 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I +T+G FG Y G +L P + +S+FE K F S +P LT + G + Sbjct: 62 IFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLT---FPIAGLGS 118 Query: 479 GAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGTMQEVIAEE--GLMGLSRG 333 G A + P +VVK L + R + +++I +E G GL++G Sbjct: 119 GLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWGFQGLNKG 170 Score = 42.4 bits (98), Expect = 0.001 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 3/79 (3%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 V G AG + L PLDVVKTR + Q +++ + Q + EGL G +GI Sbjct: 16 VAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYKSLRDSFQVIFRTEGLFGFYKGI 75 Query: 329 GPRVLHSACFAAIGYCAFE 273 P +L A+ + FE Sbjct: 76 IPPILAETPKRAVKFSTFE 94
>CRC1_YEAST (Q12289) Mitochondrial carnitine carrier| Length = 327 Score = 46.6 bits (109), Expect = 7e-05 Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 6/123 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV------ 498 I++ G L+ G ATL R+ P L ++S+E K + S+ + E V Sbjct: 184 IVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVC 243 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 318 L G +AG P+D +KT+L + + + T + + G+ G G+GP + Sbjct: 244 LAGGIAGMSMWLAVFPIDTIKTKL--QASSTRQNMLSATKEIYLQRGGIKGFFPGLGPAL 301 Query: 317 LHS 309 L S Sbjct: 302 LRS 304
>UCP3_HUMAN (P55916) Mitochondrial uncoupling protein 3 (UCP 3)| Length = 312 Score = 46.6 bits (109), Expect = 7e-05 Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +L +++T+G Y G A L R + + ++ +K K A N + +L G Sbjct: 65 ILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKG-ADNSSLTTRILAG 123 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRV---GAQGSRTVVGTM---QEVIAEEGLMGLSRGIG 327 GA++ P DVVK R + ++ R GTM + + EEG+ GL +G Sbjct: 124 CTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTL 183 Query: 326 PRVLHSACFAAIGYCAFETARLMILKSYL 240 P ++ +A ++ + +L +L Sbjct: 184 PNIMRNAIVNCAEVVTYDILKEKLLDYHL 212 Score = 39.3 bits (90), Expect = 0.011 Identities = 32/137 (23%), Positives = 59/137 (43%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I + +G GL+ G ++RN +++ LK L + P V A Sbjct: 169 IAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFG-A 227 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + + +P+DVVKTR M Q + + M +++A+EG +G P L + Sbjct: 228 GFCATVVASPVDVVKTRYMNSPPGQ-YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSW 286 Query: 299 AAIGYCAFETARLMILK 249 + + +E + ++K Sbjct: 287 NVVMFVTYEQLKRALMK 303
>ODC_PONPY (Q5RFB7) Mitochondrial 2-oxodicarboxylate carrier (Solute carrier| family 25 member 21) Length = 299 Score = 46.2 bits (108), Expect = 9e-05 Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Frame = -3 Query: 662 QILQTDGFF--GLYAGYAATLLRNLPAGVLS--YSSFEYLKAFALSKSNAPNLTPGESVL 495 QI++ +G+ GL G ATL R+ GV + Y F Y + + P L Sbjct: 156 QIIKKEGWGLQGLNKGLTATLGRH---GVFNMVYFGFYYNVKNMIPVNKDPTLEFLRKFG 212 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGIGP 324 G L+G I++ + P DV K+R+ G RT TM V EEG++ L +G+ P Sbjct: 213 IGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLP 272 Query: 323 RVLHSACFAAIGYCAFE 273 +++ A+ +E Sbjct: 273 KIMRLGPGGAVMLLVYE 289 Score = 46.2 bits (108), Expect = 9e-05 Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 11/176 (6%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I QT+ FG Y G +L P + + +FE K S +P LT + G + Sbjct: 63 IFQTERLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALT---FTIAGLGS 119 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSR-------TVVGTMQEVIAEE--GLMGLSRGIG 327 G A + P +VVK VG Q +R + VG +++I +E GL GL++G+ Sbjct: 120 GLTEAIVVNPFEVVK------VGLQANRNTFAKQPSTVGYARQIIKKEGWGLQGLNKGLT 173 Query: 326 PRVLHSACFAAIGYCAFETARLMILKSYLESCE--RKAADEMKTGVAAA*VCAIPF 165 + F + + + + MI + + E RK + +G A+ V IPF Sbjct: 174 ATLGRHGVFNMVYFGFYYNVKNMIPVNKDPTLEFLRKFGIGLLSGTIAS-VINIPF 228 Score = 38.1 bits (87), Expect = 0.024 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 3/85 (3%) Frame = -3 Query: 500 VLCGALAGAISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 ++ G AG + L PLDVVKTR + +++V + + + E L G +GI Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQTERLFGFYKGI 76 Query: 329 GPRVLHSACFAAIGYCAFETARLMI 255 P +L A+ + FE + ++ Sbjct: 77 LPPILAETPKRAVKFFTFEQYKKLL 101
>MFTC_HUMAN (Q9H2D1) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 46.2 bits (108), Expect = 9e-05 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 6/142 (4%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L I + DG GLY G + + L + + +K++ ++ A L E ++ Sbjct: 69 LTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYK-TEGRAERLEATEYLVSA 127 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGA------QGSRTVVGTMQEVIAEEGLMGLSRGIG 327 A AGA++ +T PL V KTRLM + A + + + T+ ++ EG+ GL +G Sbjct: 128 AEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFV 187 Query: 326 PRVLHSACFAAIGYCAFETARL 261 P L A+ + A+E +L Sbjct: 188 PG-LFGTSHGALQFMAYELLKL 208 Score = 40.0 bits (92), Expect = 0.006 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 3/142 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA---LSKSNAPNLTPGESV 498 L++I + +G GLY G+ L G L + ++E LK +++ L+ E + Sbjct: 170 LVKIYKYEGVRGLYKGFVPGLF-GTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYI 228 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 318 AL+ + T P VV+ RL + V+ + + +EG+ G +GI P + Sbjct: 229 SVAALSKIFAVAATYPYQVVRARLQDQHMFYSG--VIDVITKTWRKEGVGGFYKGIAPNL 286 Query: 317 LHSACFAAIGYCAFETARLMIL 252 + I + +E +L Sbjct: 287 IRVTPACCITFVVYENVSHFLL 308
>RIM2_YEAST (P38127) Mitochondrial carrier protein RIM2| Length = 377 Score = 45.8 bits (107), Expect = 1e-04 Identities = 37/149 (24%), Positives = 66/149 (44%), Gaps = 17/149 (11%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLK---------AFALSKSNAPNL 516 L +++ +GF GLY G +A+ L ++ G+L + +E +K F + Sbjct: 223 LKSVIRNEGFTGLYKGLSASYLGSV-EGILQWLLYEQMKRLIKERSIEKFGYQAEGTKST 281 Query: 515 TPGESVLC-----GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQE---VIAE 360 + C LA +++ T P +VV+TRL G R G +Q +I E Sbjct: 282 SEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRLRQTPKENGKRKYTGLVQSFKVIIKE 341 Query: 359 EGLMGLSRGIGPRVLHSACFAAIGYCAFE 273 EGL + G+ P ++ + + I + +E Sbjct: 342 EGLFSMYSGLTPHLMRTVPNSIIMFGTWE 370 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 4/121 (3%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + + +GF L+ G L+ +PA +++ ++ K N TP ++ A A Sbjct: 126 VYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYAKAFNNGQETPMIHLMAAATA 185 Query: 479 GAISAGLTTPLDVVKTRL-MTRVGAQGSRTVVGT---MQEVIAEEGLMGLSRGIGPRVLH 312 G +A T P+ ++KTR+ + + G R + ++ VI EG GL +G+ L Sbjct: 186 GWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGLSASYLG 245 Query: 311 S 309 S Sbjct: 246 S 246 Score = 38.5 bits (88), Expect = 0.018 Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 27/123 (21%) Frame = -3 Query: 530 NAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG-----------AQGS----- 399 N P + P + G + G A +T P D+VKTRL + + ++GS Sbjct: 46 NHPTVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKS 105 Query: 398 -----------RTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETARLMIL 252 + +G + V +EG L +G+GP ++ +I + + T + M Sbjct: 106 INYVIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYA 165 Query: 251 KSY 243 K++ Sbjct: 166 KAF 168
>MFTC_MACFA (Q95J75) Mitochondrial folate transporter/carrier (Solute carrier| family 25 member 32) Length = 315 Score = 45.8 bits (107), Expect = 1e-04 Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 6/142 (4%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L I + DG GLY G + + L + + +K++ ++ A L E ++ Sbjct: 69 LTTIWKLDGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYK-TEGRAERLEATEYLVSA 127 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGA------QGSRTVVGTMQEVIAEEGLMGLSRGIG 327 A AGA++ +T PL V KTRLM + A + + + T+ ++ EG+ GL +G Sbjct: 128 AEAGAMTLCITNPLWVTKTRLMLQYDAVINSPHRQYKGMFDTLVKIYKYEGVRGLYKGFV 187 Query: 326 PRVLHSACFAAIGYCAFETARL 261 P L A+ + A+E +L Sbjct: 188 PG-LFGTSHGALQFMAYELLKL 208 Score = 40.4 bits (93), Expect = 0.005 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 3/142 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFA---LSKSNAPNLTPGESV 498 L++I + +G GLY G+ L G L + ++E LK +++ L+ E + Sbjct: 170 LVKIYKYEGVRGLYKGFVPGLF-GTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYI 228 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRV 318 AL+ + T P VV+ RL + V+ + + +EG+ G +GI P + Sbjct: 229 SVAALSKIFAVAATYPYQVVRARLQDQHMFYSG--VIDVITKTWRKEGIGGFYKGIAPNL 286 Query: 317 LHSACFAAIGYCAFETARLMIL 252 + I + +E +L Sbjct: 287 IRVTPACCITFVVYENVSHFLL 308
>PM47B_CANBO (Q00319) Peroxisomal membrane protein PMP47B| Length = 419 Score = 45.8 bits (107), Expect = 1e-04 Identities = 46/156 (29%), Positives = 64/156 (41%), Gaps = 16/156 (10%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPG------ 507 L +IL+ G GLY G + L + Y +E L LS+ + P T G Sbjct: 80 LKKILKDQGAKGLYNGLESALFGIAVTNFVYYYFYE-LTGKTLSRRSNPQTTSGSKKVTL 138 Query: 506 -------ESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVI---AEE 357 +S+ GA+AG IS T P+ V TR+ QG + T++ +I E Sbjct: 139 KKGLSVWQSMAAGAVAGTISRVATNPIWVANTRMTILSKNQGKLGKLNTIEAIIYILKNE 198 Query: 356 GLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 249 G L GI P L I Y FE + I+K Sbjct: 199 GWQKLFTGIVP-ALFLVLNPIIQYTIFEQLKSFIVK 233
>ADT_KLULA (P49382) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 305 Score = 45.8 bits (107), Expect = 1e-04 Identities = 33/145 (22%), Positives = 65/145 (44%), Gaps = 7/145 (4%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGALAGAI 471 +G + G A ++R P L+++ + +KA F K ++ G LAG + Sbjct: 68 EGVASFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGLAGGL 127 Query: 470 SAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 S LD +TRL + G + +V ++ +A +G+ GL RG P V+ Sbjct: 128 SLLFVYSLDYARTRLAADSKSAKKGGERQFNGLVDVYKKTLASDGVAGLYRGFLPSVVGI 187 Query: 308 ACFAAIGYCAFETARLMILKSYLES 234 + + + +++ + ++L LE+ Sbjct: 188 VVYRGLYFGLYDSLKPLLLTGSLEN 212 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 5/127 (3%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L +DG GLY G+ +++ + L + ++ LK L+ S S L L G Sbjct: 168 LASDGVAGLYRGFLPSVVGIVVYRGLYFGLYDSLKPLLLTGSLE------NSFLASFLLG 221 Query: 476 -AISAGLTT---PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 A++ G +T PLD V+ R+M G A ++++A EG+ L +G G +L Sbjct: 222 WAVTTGASTASYPLDTVRRRMMMTSGQAVKYDGAFDAFRKIVAAEGIKSLFKGCGANILR 281 Query: 311 SACFAAI 291 A + Sbjct: 282 GVAGAGV 288
>YAD8_SCHPO (Q09834) Putative mitochondrial carrier C4G8.08| Length = 271 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 13/143 (9%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN--APNLTPGESVLCGA 486 + +++G G Y GY + LP V + +E K + +SN + P +C A Sbjct: 126 LARSEGLKGFYRGYWMGVAIYLPTTVSWWVCYEESKKYLQKQSNWDISVIAP----ICSA 181 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQE-----------VIAEEGLMGLS 339 L ++ ++TPLD+VKTR + + G E + ++ G+ G + Sbjct: 182 LGTVVATTISTPLDIVKTRYQVATSSAMRKAEYGLQAEKELGILEIAKLLFSKHGVKGFT 241 Query: 338 RGIGPRVLHSACFAAIGYCAFET 270 RG+ R+ + I FE+ Sbjct: 242 RGLFTRMCYIMPSGMISMSVFES 264 Score = 40.4 bits (93), Expect = 0.005 Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 5/112 (4%) Frame = -3 Query: 653 QTDGFFGLYAGYAATLLRNLPAGV--LSYSSFEYLKAFALSKSN-APNLTPGESV--LCG 489 QT G F R LP + ++ ++ YL + +K P++ G + +CG Sbjct: 31 QTIGKFSFKTMPLKAYYRGLPISLTLITPATCLYLSTYVEAKRRFKPSVGEGAILYSICG 90 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRG 333 A +S+ + TPL+V+K R T++ +GS V+ T+ + EGL G RG Sbjct: 91 MTAEVVSSFVWTPLEVIKAR--TQISQKGS--VINTISTLARSEGLKGFYRG 138
>ADT2_YEAST (P18239) ADP,ATP carrier protein 2 (ADP/ATP translocase 2) (Adenine| nucleotide translocator 2) (ANT 2) Length = 318 Score = 45.4 bits (106), Expect = 2e-04 Identities = 32/144 (22%), Positives = 64/144 (44%), Gaps = 7/144 (4%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGALAGAI 471 +G + G A ++R P L+++ + +KA F K ++ G AGA+ Sbjct: 81 EGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGAL 140 Query: 470 SAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 S LD +TRL + GA+ ++ ++ + +G+ GL RG P V+ Sbjct: 141 SLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGI 200 Query: 308 ACFAAIGYCAFETARLMILKSYLE 237 + + + +++ + ++L LE Sbjct: 201 VVYRGLYFGMYDSLKPLLLTGSLE 224 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 4/126 (3%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L++DG GLY G+ +++ + L + ++ LK L+ S G + L Sbjct: 181 LKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGS-----LEGSFLASFLLGW 235 Query: 476 AISAGLTT---PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 ++ G +T PLD V+ R+M G A +++++A EG+ L +G G +L Sbjct: 236 VVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRG 295 Query: 308 ACFAAI 291 A + Sbjct: 296 VAGAGV 301
>ODC2_YEAST (Q99297) Mitochondrial 2-oxodicarboxylate carrier 2| Length = 307 Score = 45.4 bits (106), Expect = 2e-04 Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 3/116 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I++ +GF LY G ++ +L P ++ + + + N T S+ G Sbjct: 66 LKKIVKKEGFSRLYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNETTQKISIAAG 125 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGI 330 A AG A + P +++K R+ + +G M ++ I EG+MGL +GI Sbjct: 126 ASAGMTEAAVIVPFELIKIRMQ-----DVKSSYLGPMDCLKKTIKNEGIMGLYKGI 176 Score = 43.9 bits (102), Expect = 4e-04 Identities = 34/127 (26%), Positives = 59/127 (46%), Gaps = 6/127 (4%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRN-LPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 492 L + ++ +G GLY G +T+ RN L G ++ + ++K+ ++ Sbjct: 160 LKKTIKNEGIMGLYKGIESTMWRNALWNGGYFGVIYQVRNSMPVAKTKGQKTR--NDLIA 217 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGLMGLSRGIG 327 GA+ G + L TP DVVK+R+ + V A S + ++ + EEG L +G Sbjct: 218 GAIGGTVGTMLNTPFDVVKSRIQS-VDAVSSAVKKYNWCLPSLLVIYREEGFRALYKGFV 276 Query: 326 PRVLHSA 306 P+V A Sbjct: 277 PKVCRLA 283 Score = 37.4 bits (85), Expect = 0.041 Identities = 30/88 (34%), Positives = 41/88 (46%), Gaps = 10/88 (11%) Frame = -3 Query: 539 SKSNAPNLTPGESVLCGALAGAISAGLTTPLDVVKTRLM--------TRVGAQGSR--TV 390 S SNA L + GA+AG + PLDVVKTR VG Q R V Sbjct: 3 SDSNAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGV 62 Query: 389 VGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 + +++++ +EG L RGI +L A Sbjct: 63 IDCLKKIVKKEGFSRLYRGISSPMLMEA 90
>ADT_SCHPO (Q09188) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 322 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 9/146 (6%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYS---SFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 +G L+ G A +LR P L+++ F+ + + + G ++ G AG Sbjct: 85 EGVISLWRGNTANVLRYFPTQALNFAFKDKFKKMFGYKKERDGYAKWFAG-NLASGGAAG 143 Query: 476 AISAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 A S LD +TRL + G + +V ++ +GL GL RG GP V+ Sbjct: 144 AASLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTYRSDGLRGLYRGFGPSVV 203 Query: 314 HSACFAAIGYCAFETARLMILKSYLE 237 + + + ++T + ++L LE Sbjct: 204 GIVVYRGLYFGMYDTLKPVVLVGPLE 229 Score = 35.0 bits (79), Expect = 0.20 Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 1/122 (0%) Frame = -3 Query: 653 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGA 474 ++DG GLY G+ +++ + L + ++ LK L N S L G Sbjct: 187 RSDGLRGLYRGFGPSVVGIVVYRGLYFGMYDTLKPVVLVGPLEGNFL--ASFLLGWAVTT 244 Query: 473 ISAGLTTPLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFA 297 S + PLD ++ R+M G A + ++++A+EG +G G +L A Sbjct: 245 GSGVASYPLDTIRRRMMMTSGEAVKYSSSFECGRQILAKEGARSFFKGAGANILRGVAGA 304 Query: 296 AI 291 + Sbjct: 305 GV 306
>UCP1_MESAU (P04575) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/138 (25%), Positives = 61/138 (44%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+ F L+ G LLRN+ + +++ +K ++ + P +L +A Sbjct: 163 IATTESFSTLWKGTTPNLLRNVIINCVELVTYDLMKGALVNNQILADDVPCH-LLSAFVA 221 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L +P DVVKTR + + Q +V ++ +EG +G P L A + Sbjct: 222 GFCTTFLASPADVVKTRFINSLPGQ-YPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASW 280 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + + KS Sbjct: 281 NVIMFVCFEQLKKELSKS 298 Score = 37.0 bits (84), Expect = 0.054 Identities = 28/133 (21%), Positives = 54/133 (40%), Gaps = 4/133 (3%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + +T+G LY+G A + R + L ++ ++ + S P T G + G + Sbjct: 64 LAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPP-TLGNRISAGLMT 122 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVLH 312 G ++ + P +VVK RL + G + GT + E L +G P +L Sbjct: 123 GGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLLR 182 Query: 311 SACFAAIGYCAFE 273 + + ++ Sbjct: 183 NVIINCVELVTYD 195 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Frame = -3 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGL 351 T G + +A ++ +T PLD K RL + Q S T V+GT+ + EGL Sbjct: 11 TMGVKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQISSTIRYKGVLGTITTLAKTEGL 70 Query: 350 MGLSRGIGPRVLHSACFAAIGYCAFETAR 264 L G+ + FA++ ++T + Sbjct: 71 PKLYSGLPAGIQRQISFASLRIGLYDTVQ 99
>UCP1_DICGR (Q8K404) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 44.7 bits (104), Expect = 3e-04 Identities = 34/138 (24%), Positives = 61/138 (44%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+ F L+ G L+RN+ +++ +K ++ + P +L +A Sbjct: 164 IATTESFSTLWKGTTPNLMRNVIINRTELVTYDLMKGALVNNQILADDVPCH-LLSALVA 222 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L +P DVVKTR + + Q +V ++ +EG +G P L A + Sbjct: 223 GFCTTFLASPADVVKTRFINSLPGQ-YPSVPSCAMTMLTKEGPTAFFKGFVPSFLRLASW 281 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + ++KS Sbjct: 282 NVIMFVCFEQLKKELMKS 299 Score = 36.2 bits (82), Expect = 0.092 Identities = 27/121 (22%), Positives = 52/121 (42%), Gaps = 4/121 (3%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + +T+G+ LY+G A + R + L ++ ++ + S P T G + G + Sbjct: 65 LAKTEGWPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPP-TLGNRISAGLMT 123 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVLH 312 G ++ + P +VVK RL + G + GT + E L +G P ++ Sbjct: 124 GGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESFSTLWKGTTPNLMR 183 Query: 311 S 309 + Sbjct: 184 N 184
>ADT1_WHEAT (Q41629) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 331 Score = 44.3 bits (103), Expect = 3e-04 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 8/150 (5%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + G ++ G Sbjct: 86 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRMFNFKKDKDGYWKWFGGNLASGGA 145 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQ---GSRT---VVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 146 AGASSLFFVYSLDYARTRLANDAKASKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 205 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLESC 231 + + + + +++ + ++L L+ C Sbjct: 206 CVGIIVYRGLYFGLYDSLKPVLLTGTLQVC 235 Score = 41.6 bits (96), Expect = 0.002 Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 8/130 (6%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L++DG GLY G+ + + G++ Y F L S P L G +C + Sbjct: 190 LKSDGIAGLYRGFNISCV-----GIIVYRGLY----FGLYDSLKPVLLTGTLQVCFFASF 240 Query: 476 AIS------AGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 A+ AGL + P+D V+ R+M G A ++ + Q+++ +EG L +G G Sbjct: 241 ALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGAKSLFKGAGAN 300 Query: 320 VLHSACFAAI 291 +L + A + Sbjct: 301 ILRAIAGAGV 310
>MPCP_YEAST (P23641) Mitochondrial phosphate carrier protein (Phosphate| transport protein) (PTP) (mPic 1) (Mitochondrial import receptor) (p32) Length = 311 Score = 44.3 bits (103), Expect = 3e-04 Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Frame = -3 Query: 488 ALAGAISAGLT----TPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 ALAGAI G T P+DVVKTR+ ++ +VG+ +++IA EG L G GP Sbjct: 21 ALAGAIGCGSTHSSMVPIDVVKTRIQLEPTVY-NKGMVGSFKQIIAGEGAGALLTGFGPT 79 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGV 195 +L + A + +E + K ++++ A K V Sbjct: 80 LLGYSIQGAFKFGGYEVFK----KFFIDNLGYDTASRYKNSV 117 Score = 37.0 bits (84), Expect = 0.054 Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 3/135 (2%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE-SVLCG- 489 QI+ +G L G+ TLL G + +E K F + + + SV G Sbjct: 62 QIIAGEGAGALLTGFGPTLLGYSIQGAFKFGGYEVFKKFFIDNLGYDTASRYKNSVYMGS 121 Query: 488 -ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 A+A ++ PL+ + RL+++ Q + +VG ++ EEG+ G P + Sbjct: 122 AAMAEFLADIALCPLEATRIRLVSQ--PQFANGLVGGFSRILKEEGIGSFYSGFTPILFK 179 Query: 311 SACFAAIGYCAFETA 267 + + FE A Sbjct: 180 QIPYNIAKFLVFERA 194
>MCATL_HUMAN (Q8N8R3) Mitchondrial carnitine/acylcarnitine carrier protein CACL| (CACT-like) (Solute carrier family 25 member 29) Length = 303 Score = 44.3 bits (103), Expect = 3e-04 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 7/133 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L QI +G G+ G +TLLR P+ + + +++ L AL L + +L G Sbjct: 138 LAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTR-ALGCEPGDRLLVPKLLLAG 196 Query: 488 ALAGAISAGLTTPLDVVKTRLMT--RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 +G +S T P+DVVK+RL GA R ++ + + EG +RG+ +L Sbjct: 197 GTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLL 256 Query: 314 -----HSACFAAI 291 ++A FA + Sbjct: 257 RAFPVNAATFATV 269 Score = 39.3 bits (90), Expect = 0.011 Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Frame = -3 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQ---EVIAEEGLMG 345 +P L GA AGAI + P+++ KTRL + A +RT G++ ++ EGL G Sbjct: 91 SPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQ-DAGPARTYKGSLDCLAQIYGHEGLRG 149 Query: 344 LSRGI 330 ++RG+ Sbjct: 150 VNRGM 154 Score = 29.6 bits (65), Expect = 8.6 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRTVVGTMQEVIAEEGLMGLSRGIG 327 L G G + P D VK RL + V R + + +I +E ++GL +G+G Sbjct: 6 LAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLG 63
>YE08_SCHPO (O13805) Putative mitochondrial carrier C17H9.08| Length = 326 Score = 43.5 bits (101), Expect = 6e-04 Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 6/109 (5%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 G GLY G+ ATL R P + + ++E ++ + + + T L G+LAG S Sbjct: 74 GLHGLYQGHTATLYRVFPYAGIKFVAYEQVRRVLI--RDPEHETHARRFLSGSLAGTCSV 131 Query: 464 GLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLM------GLSR 336 T PL++++ RL + T+ +++ E + GLSR Sbjct: 132 FFTYPLELIRVRLAYITNTGKNPTLTQVTKDIFHERDFLCNKKYPGLSR 180
>YFL5_YEAST (P43617) Putative mitochondrial carrier YFR045W| Length = 285 Score = 43.5 bits (101), Expect = 6e-04 Identities = 27/133 (20%), Positives = 57/133 (42%) Frame = -3 Query: 653 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGA 474 QT G G AT+ R + + ++++ K ++++ + SV+ G Sbjct: 152 QTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQARNDKAS-----SVITGLATSF 206 Query: 473 ISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAA 294 +T P+DVVKTR+M++ + + M + +EG+ +G R + Sbjct: 207 TLVAMTQPIDVVKTRMMSQNAKTEYKNTLNCMYRIFVQEGMATFWKGSIFRFMKVGISGG 266 Query: 293 IGYCAFETARLMI 255 + + +E L++ Sbjct: 267 LTFTVYEQVSLLL 279
>UCP1_BOVIN (P10861) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) (Fragment) Length = 288 Score = 43.5 bits (101), Expect = 6e-04 Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 4/147 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 ++ + +T+G LY+G A L R + L ++ ++ F + A + G + G Sbjct: 46 IITLAKTEGPVKLYSGLPAGLQRQISLASLRIGLYDTVQEFFTTGKEA---SLGSKISAG 102 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPR 321 + G ++ + P +VVK RL + G + GT + EGL GL +G P Sbjct: 103 LMTGGVAVFIGQPTEVVKVRLQAQSHLHGPKPRYTGTYNAYRIIATTEGLTGLWKGTSPN 162 Query: 320 VLHSACFAAIGYCAFETARLMILKSYL 240 + + ++ + ++K+ L Sbjct: 163 LTTNVIINCTELVTYDLMKEALVKNKL 189 Score = 38.1 bits (87), Expect = 0.024 Identities = 32/137 (23%), Positives = 58/137 (42%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+G GL+ G + L N+ +++ +K + + P V +A Sbjct: 146 IATTEGLTGLWKGTSPNLTTNVIINCTELVTYDLMKEALVKNKLLADDVPCHFV-SAVVA 204 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L++P+DVVKTR + Q + +V ++ EG +G P L + Sbjct: 205 GFCTTVLSSPVDVVKTRFVNSSPGQNT-SVPNCAMMMLTREGPSAFFKGFVPSFLRLGSW 263 Query: 299 AAIGYCAFETARLMILK 249 + C FE + ++K Sbjct: 264 NIMFVC-FERLKQELMK 279
>UCP1_PHOSU (Q9ER18) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 307 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/138 (24%), Positives = 59/138 (42%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+ L+ G LLRN+ +++ +K ++ + P +L +A Sbjct: 164 IATTESLSTLWKGTTPNLLRNVIINCTELVTYDLMKGALVNNQILADDVPCH-LLSALVA 222 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L +P DVVKTR + + Q +V + +EG +G P L A + Sbjct: 223 GFCTTFLASPADVVKTRFINSLPGQ-YPSVPSCAMTMFTKEGPTAFFKGFVPSFLRLASW 281 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + ++KS Sbjct: 282 NVIMFVCFEQLKKELMKS 299 Score = 35.8 bits (81), Expect = 0.12 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Frame = -3 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGL 351 T G + +A ++ +T PLD K RL + Q S T V+GT+ + EGL Sbjct: 12 TMGVKIFSAGVAACLADIITFPLDTAKVRLQIQGEGQTSSTIRYKGVLGTITTLAKTEGL 71 Query: 350 MGLSRGIGPRVLHSACFAAIGYCAFETAR 264 L G+ + FA++ ++T + Sbjct: 72 PKLYSGLPAGIQRQISFASLRIGLYDTVQ 100 Score = 35.4 bits (80), Expect = 0.16 Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 5/122 (4%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKA-FALSKSNAPNLTPGESVLCGAL 483 + +T+G LY+G A + R + L ++ ++ F+ K P L + G + Sbjct: 65 LAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGKETPPTLV--NRISAGLM 122 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVL 315 G ++ + P +VVK RL + G + GT + E L L +G P +L Sbjct: 123 TGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTESLSTLWKGTTPNLL 182 Query: 314 HS 309 + Sbjct: 183 RN 184
>ADT2_WHEAT (Q41630) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 331 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 8/150 (5%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + G ++ G Sbjct: 86 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRMFNFKKDKDGYWKWFGGNLASGGA 145 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQ---GSRT---VVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 146 AGASSLFFVYSLDYGRTRLANDAKASKGGGDRQFNGLVDVYRKTLKSDGIAGLYRGFNIS 205 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLESC 231 + + + + +++ + ++L L+ C Sbjct: 206 CVGIIVYRGLYFGLYDSLKPVLLTGTLQVC 235 Score = 42.7 bits (99), Expect = 0.001 Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 8/130 (6%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L++DG GLY G+ + + G++ Y F L S P L G +C + Sbjct: 190 LKSDGIAGLYRGFNISCV-----GIIVYRGLY----FGLYDSLKPVLLTGTLQVCSFASF 240 Query: 476 AIS------AGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 A+ AGL + P+D V+ R+M G A ++ + Q++ A+EG L +G G Sbjct: 241 ALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQIPAKEGAKSLFKGAGAN 300 Query: 320 VLHSACFAAI 291 +L + A + Sbjct: 301 ILRAIAGAGV 310
>ADT1_BOVIN (P02722) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart isoform T1) Length = 297 Score = 43.1 bits (100), Expect = 7e-04 Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 13/151 (8%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 516 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG---AQGSRTVVGT-MQEVIAEEGLM 348 G + AGA S PLD +TRL VG AQ T +G + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGAAQREFTGLGNCITKIFKSDGLR 170 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 34.7 bits (78), Expect = 0.27 Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 + +I ++DG GLY G+ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 ITKIFKSDGLRGLYQGFNVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 330 +A ++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQTVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGPKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ARG13_NEUCR (Q01356) Amino acid transporter arg-13| Length = 363 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 13/123 (10%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL---- 495 Q ++ DGF GLY G +A L+ L SS + + S + P +S L Sbjct: 90 QSIRADGFLGLYRGISAPLV----GAALENSSLFFFERIGRSLLYSSGFAPRDSELSLSA 145 Query: 494 ---CGALAGAISAGLTTPLDVVKTRLMT--RVGAQGSR----TVVGTMQEVIAEEGLMGL 342 G +GA ++ + TP+++VK ++ G G+R + ++E+ EGL G Sbjct: 146 LWFTGGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGF 205 Query: 341 SRG 333 G Sbjct: 206 WHG 208
>M2OM_MOUSE (Q9CR62) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 43.1 bits (100), Expect = 7e-04 Identities = 41/149 (27%), Positives = 60/149 (40%), Gaps = 8/149 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPG--ESVL 495 L IL+T+G G+Y G +A LLR + L P PG L Sbjct: 67 LTSILKTEGLKGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTP---PGFLLKAL 123 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVG------AQGSRTVVGTMQEVIAEEGLMGLSRG 333 G AGA A + TP +V R MT G +G + V + + EEG+ L RG Sbjct: 124 IGMTAGATGAFVGTPAEVALIR-MTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRG 182 Query: 332 IGPRVLHSACFAAIGYCAFETARLMILKS 246 P + + A ++ ++ +L S Sbjct: 183 CIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 38.9 bits (89), Expect = 0.014 Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 7/122 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I + +G L+ G T+ R + +S+ K F L +++LC Sbjct: 167 LVRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNILCH 221 Query: 488 ALAGAISAGLTT----PLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGI 330 A IS +TT P+D+VKTR+ G + + + +V+ EG L +G Sbjct: 222 FCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLLKVVRYEGFFSLWKGF 281 Query: 329 GP 324 P Sbjct: 282 TP 283 Score = 32.0 bits (71), Expect = 1.7 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 333 L G LAG + PLD+VK R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVKNRM--QLSGEGAKTREYKTSFHALTSILKTEGLKGIYTG 82 Query: 332 IGPRVLHSACF 300 + +L A + Sbjct: 83 LSAGLLRQATY 93
>M2OM_BOVIN (P22292) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 42.4 bits (98), Expect = 0.001 Identities = 39/149 (26%), Positives = 61/149 (40%), Gaps = 8/149 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPG--ESVL 495 L+ IL+ +G G+Y G +A LLR + L P PG + Sbjct: 67 LISILRAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTP---PGFLLKAV 123 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVG------AQGSRTVVGTMQEVIAEEGLMGLSRG 333 G AGA A + TP +V R MT G +G + V + ++ EEG+ L RG Sbjct: 124 IGMTAGATGAFVGTPAEVALIR-MTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTLWRG 182 Query: 332 IGPRVLHSACFAAIGYCAFETARLMILKS 246 P + + A ++ ++ +L S Sbjct: 183 CIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 7/122 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I+Q +G L+ G T+ R + +S+ K F L +++LC Sbjct: 167 LFRIVQEEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNILCH 221 Query: 488 ALAGAISAGLTT----PLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGI 330 A IS +TT P+D+VKTR+ G + + + +V+ EG L +G Sbjct: 222 FCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEYKNGLDVLVKVVRYEGFFSLWKGF 281 Query: 329 GP 324 P Sbjct: 282 TP 283 Score = 31.2 bits (69), Expect = 2.9 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 333 L G LAG + PLD+VK R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVKNRM--QLSGEGAKTREYKTSFHALISILRAEGLRGIYTG 82 Query: 332 IGPRVLHSACF 300 + +L A + Sbjct: 83 LSAGLLRQATY 93
>LEU5_YEAST (P38702) Mitochondrial carrier protein LEU5| Length = 357 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/74 (31%), Positives = 40/74 (54%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAIS 468 DG G + G++ATLLR P + + ++E ++ + + ++ G+LAG S Sbjct: 89 DGVRGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKEFE--SHWRRLVSGSLAGLCS 146 Query: 467 AGLTTPLDVVKTRL 426 +T PLD+V+ RL Sbjct: 147 VFITYPLDLVRVRL 160
>ADT_CHLKE (P31692) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 339 Score = 42.4 bits (98), Expect = 0.001 Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 11/171 (6%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE------ 504 +++ G + G A ++R P +++ + +K P +P Sbjct: 94 VRVSSEQGVASFWRGNLANVVRYFPTQAFNFAFKDTIKGLF------PKYSPKTDFWRFF 147 Query: 503 --SVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVG---TMQEVIAEEGLMGLS 339 ++ G LAGA S + PLD +TRL VG+ SR G + +V+ G M L Sbjct: 148 VVNLASGGLAGAGSLLIVYPLDFARTRLAADVGSGKSREFTGLVDCLSKVVKRGGPMALY 207 Query: 338 RGIGPRVLHSACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVAAA 186 +G G V + + ++TA+ ++ K ER A K VA A Sbjct: 208 QGFGVSVQGIIVYRGAYFGLYDTAKGVLFKD-----ERTANFFAKWAVAQA 253 Score = 33.1 bits (74), Expect = 0.78 Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 3/124 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L ++++ G LY G+ ++ + + ++ K N +V Sbjct: 194 LSKVVKRGGPMALYQGFGVSVQGIIVYRGAYFGLYDTAKGVLFKDERTANFFAKWAVAQA 253 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTM---QEVIAEEGLMGLSRGIGPRV 318 AGA L+ P D V+ RLM + G G R GT+ ++V +EG+ +G V Sbjct: 254 VTAGA--GVLSYPFDTVRRRLMMQSG--GERQYNGTIDCWRKVAQQEGMKAFFKGAWSNV 309 Query: 317 LHSA 306 L A Sbjct: 310 LRGA 313
>ADT3_BOVIN (P32007) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) (ANT 2) Length = 297 Score = 42.0 bits (97), Expect = 0.002 Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 IVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 488 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 336 LA +AG T+ PLD +TRL VG GS R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKSGSEREFRGLGDCLVKITKSDGIRGLYQ 174 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMI 255 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 36.6 bits (83), Expect = 0.070 Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKITKSDGIRGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIVVSW 213 Query: 488 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSRGI 330 +A ++A ++ P D V+ R+M + G +G+ + V ++++ +EG +G Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYKGTVDCWRKILKDEGGKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ADT1_RABIT (O46373) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (30 kDa calsequestrin-binding protein) (CSQ-binding 30 kDa protein) Length = 297 Score = 42.0 bits (97), Expect = 0.002 Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 13/151 (8%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 516 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVG---AQGSRTVVGT-MQEVIAEEGLM 348 G + AGA S PLD +TRL VG AQ + +G + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGAAQREFSGLGNCLTKIFKSDGLR 170 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 36.2 bits (82), Expect = 0.092 Identities = 30/125 (24%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I ++DG GLY G+ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 LTKIFKSDGLRGLYQGFNVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 330 +A ++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQTVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWKKIAKDEGAKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>UCP1_RABIT (P14271) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 4/121 (3%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 + +T+G LY+G A L R + L ++ ++ F S P+L G + G Sbjct: 65 LAKTEGPLKLYSGLPAGLQRQISFASLRIGLYDTVQEFFTSGEETPSL--GSKISAGLTT 122 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSR-TVVGTMQE---VIAEEGLMGLSRGIGPRVLH 312 G ++ + P +VVK RL + G + GT + E L L +G P +L Sbjct: 123 GGVAVFIGQPTEVVKVRLQAQSHLHGLKPRYTGTYNAYRIIATTESLTSLWKGTTPNLLR 182 Query: 311 S 309 + Sbjct: 183 N 183 Score = 39.3 bits (90), Expect = 0.011 Identities = 32/138 (23%), Positives = 58/138 (42%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+ L+ G LLRN+ +++ +K + + P V +A Sbjct: 163 IATTESLTSLWKGTTPNLLRNVIINCTELVTYDLMKGALVRNEILADDVPCHFV-SALIA 221 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L++P+DVVKTR + Q + +V + +EG +G P L + Sbjct: 222 GFCTTLLSSPVDVVKTRFINSPPGQYA-SVPNCAMTMFTKEGPTAFFKGFVPSFLRLGSW 280 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + +++S Sbjct: 281 NVIMFVCFEKLKGELMRS 298
>ADT_CHLRE (P27080) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 308 Score = 42.0 bits (97), Expect = 0.002 Identities = 30/146 (20%), Positives = 65/146 (44%), Gaps = 8/146 (5%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYS-SFEYLKAFALSKSNAPNLTPGESVLCG 489 ++ ++ +GF L+ G A ++R P L+++ ++ + F +K ++ G Sbjct: 60 VRTVREEGFGSLWRGNTANVIRYFPTQALNFAFKDKFKRMFGFNKDKEYWKWFAGNMASG 119 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRV-------GAQGSRTVVGTMQEVIAEEGLMGLSRGI 330 AGA+S LD +TRL G + +V ++ IA +G+ GL RG Sbjct: 120 GAAGAVSLSFVYSLDYARTRLANDAKSAKKGGGDRQFNGLVDVYRKTIASDGIAGLYRGF 179 Query: 329 GPRVLHSACFAAIGYCAFETARLMIL 252 + + + + +++ + ++L Sbjct: 180 NISCVGIVVYRGLYFGMYDSLKPVVL 205 Score = 40.8 bits (94), Expect = 0.004 Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 5/127 (3%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 + +DG GLY G+ + + + L + ++ LK L A N L L G Sbjct: 167 IASDGIAGLYRGFNISCVGIVVYRGLYFGMYDSLKPVVLVGPLANNF------LAAFLLG 220 Query: 476 ---AISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 I AGL + P+D ++ R+M G A + QE++ EG+ L +G G +L Sbjct: 221 WGITIGAGLASYPIDTIRRRMMMTSGSAVKYNSSFHCFQEIVKNEGMKSLFKGAGANILR 280 Query: 311 SACFAAI 291 + A + Sbjct: 281 AVAGAGV 287
>ADT_ORYSA (P31691) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 382 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/148 (20%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + G ++ G Sbjct: 137 IKDEGFASLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDKDGYWKWFGGNLASGGA 196 Query: 482 AGAISAGLTTPLDVVKTRLMTRV------GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LD +TRL G + +V ++ + +G+ GL RG Sbjct: 197 AGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 256 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLE 237 + + + + +++ + ++L L+ Sbjct: 257 CVGIIVYRGLYFGMYDSLKPVVLTGSLQ 284 Score = 38.9 bits (89), Expect = 0.014 Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 2/124 (1%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L++DG GLY G+ + + + L + ++ LK L+ S N S G L Sbjct: 241 LKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVVLTGSLQDNFF--ASFALGWLI- 297 Query: 476 AISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AGL + P+D V+ R+M G A ++ + +++ EG L +G G +L + Sbjct: 298 TNGAGLASYPIDTVRRRMMMTSGEAVKYKSSMDAFSQILKNEGAKSLFKGAGANILRAIA 357 Query: 302 FAAI 291 A + Sbjct: 358 GAGV 361
>ADT1_RAT (Q05962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) Length = 297 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 516 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT----VVGTMQEVIAEEGLM 348 G + AGA S PLD +TRL VG S+ + + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLK 170 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFSVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 37.4 bits (85), Expect = 0.041 Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I ++DG GLY G++ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 LTKIFKSDGLKGLYQGFSVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 330 +A +++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGRKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ADT1_MOUSE (P48962) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (mANC1) Length = 297 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 516 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNL 116 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT----VVGTMQEVIAEEGLM 348 G + AGA S PLD +TRL VG S+ + + ++ +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLK 170 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFSVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 37.7 bits (86), Expect = 0.031 Identities = 31/125 (24%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L +I ++DG GLY G++ ++ G++ Y + Y + +K P+ ++ Sbjct: 160 LTKIFKSDGLKGLYQGFSVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIIVSW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 330 +A +++A GL + P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>PM47A_CANBO (P21245) Peroxisomal membrane protein PMP47A| Length = 423 Score = 41.6 bits (96), Expect = 0.002 Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 16/156 (10%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN---------- 519 L +IL+ G GLY G + L + Y +E L L++ + P Sbjct: 80 LKKILKDQGAKGLYNGLESALFGIAVTNFVYYYFYE-LTGKTLNRRSNPQTASNSKKVAL 138 Query: 518 ---LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVI---AEE 357 L+ +S+ GA+AG IS T P+ V TR+ QG + T++ +I E Sbjct: 139 KKGLSVWQSMAAGAVAGTISRVATNPIWVANTRMTILSKNQGKLGKLNTIEAIIYILKNE 198 Query: 356 GLMGLSRGIGPRVLHSACFAAIGYCAFETARLMILK 249 G L GI P L I Y FE + I+K Sbjct: 199 GWQKLFTGIVP-ALFLVLNPIIQYTIFEQLKSFIVK 233
>MPCP_BOVIN (P12234) Phosphate carrier protein, mitochondrial precursor (PTP)| (Solute carrier family 25 member 3) Length = 362 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF---ALSKSNAPNLTPGESVLCGA 486 L+ DGF GL G+A T + G+ + +E K L + NA + A Sbjct: 111 LKEDGFRGLAKGWAPTFIGYSLQGLCKFGFYEVFKVLYSNMLGEENAYLWRTSLYLAASA 170 Query: 485 LAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSA 306 A + P++ K R+ T+ G + T+ ++ EEGL +G+ P + Sbjct: 171 SAEFFADIALAPMEAAKVRIQTQPGY--ANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQI 228 Query: 305 CFAAIGYCAFE 273 + + + FE Sbjct: 229 PYTMMKFACFE 239
>ADT2_PONPY (Q5R5A1) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 41.2 bits (95), Expect = 0.003 Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 9/147 (6%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +++I + G + G A ++R+ P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRHFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 488 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 336 LA +AG T+ PLD +TRL VG G+ R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQ 174 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMI 255 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 39.3 bits (90), Expect = 0.011 Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 9/137 (6%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 330 +A ++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGA 273 Query: 329 GPRVLH--SACFAAIGY 285 VL FA + Y Sbjct: 274 WSNVLRGMGGAFALVLY 290
>ORT1_YEAST (Q12375) Mitochondrial ornithine carrier protein| Length = 292 Score = 41.2 bits (95), Expect = 0.003 Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 5/135 (3%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I+ G GL+ G + T +R GV ++++E +K + + + ES + L Sbjct: 159 IITERGLAGLWQGQSGTFIRESFGGVAWFATYEIVKKSLKDRHSLDDPKRDESKIWELLI 218 Query: 479 GAISAGLTT-----PLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVL 315 SAGL P D VK+ + T ++ ++++ + GL G RG+G + Sbjct: 219 SGGSAGLAFNASIFPADTVKSVMQTE-----HISLTNAVKKIFGKFGLKGFYRGLGITLF 273 Query: 314 HSACFAAIGYCAFET 270 + A + FET Sbjct: 274 RAVPANAAVFYIFET 288
>UCP1_RAT (P04633) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/138 (23%), Positives = 59/138 (42%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+ L+ G L+RN+ +++ +K ++ + P +L +A Sbjct: 163 IATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVNHHILADDVPCH-LLSALVA 221 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L +P+DVVKTR + + Q +V + +EG +G P L + Sbjct: 222 GFCTTLLASPVDVVKTRFINSLPGQ-YPSVPSCAMTMYTKEGPAAFFKGFAPSFLRLGSW 280 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + ++KS Sbjct: 281 NVIMFVCFEQLKKELMKS 298 Score = 35.4 bits (80), Expect = 0.16 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Frame = -3 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRT-----VVGTMQEVIAEEGL 351 T G + ++ ++ +T PLD K RL + Q S T V+GT+ + EGL Sbjct: 11 TMGVKIFSAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGL 70 Query: 350 MGLSRGIGPRVLHSACFAAIGYCAFETAR 264 L G+ + FA++ ++T + Sbjct: 71 PKLYSGLPAGIQRQISFASLRIGLYDTVQ 99
>M2OM_HUMAN (Q02978) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 41.2 bits (95), Expect = 0.003 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 8/149 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPG--ESVL 495 L IL+ +G G+Y G +A LLR + L P PG + Sbjct: 67 LTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTP---PGFLLKAV 123 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVG------AQGSRTVVGTMQEVIAEEGLMGLSRG 333 G AGA A + TP +V R MT G +G + V + + EEG++ L RG Sbjct: 124 IGMTAGATGAFVGTPAEVALIR-MTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRG 182 Query: 332 IGPRVLHSACFAAIGYCAFETARLMILKS 246 P + + A ++ ++ +L S Sbjct: 183 CIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 38.9 bits (89), Expect = 0.014 Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 7/122 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I + +G L+ G T+ R + +S+ K F L +++LC Sbjct: 167 LIRITREEGVLTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNILCH 221 Query: 488 ALAGAISAGLTT----PLDVVKTRLMTRVGAQGS---RTVVGTMQEVIAEEGLMGLSRGI 330 A IS +TT P+D+ KTR+ G + + + +V+ EG L +G Sbjct: 222 FCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGF 281 Query: 329 GP 324 P Sbjct: 282 TP 283 Score = 32.0 bits (71), Expect = 1.7 Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 333 L G LAG + PLD+VK R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVKNRM--QLSGEGAKTREYKTSFHALTSILKAEGLRGIYTG 82 Query: 332 IGPRVLHSACF 300 + +L A + Sbjct: 83 LSAGLLRQATY 93
>ADT3_HUMAN (P12236) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) (ADP,ATP carrier protein, isoform T2) Length = 297 Score = 40.8 bits (94), Expect = 0.004 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 516 +++I + G + G A ++R P L+++ + K L + A NL Sbjct: 57 IVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNL 116 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLM 348 G + AGA S PLD +TRL VG G+ R + + ++ +G+ Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIR 170 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFSVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 36.6 bits (83), Expect = 0.070 Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G++ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKITKSDGIRGLYQGFSVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNTHIVVSW 213 Query: 488 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 330 +A ++A ++ P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ADT1_YEAST (P04710) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 309 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/126 (24%), Positives = 54/126 (42%), Gaps = 4/126 (3%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L+TDG GLY G+ ++L + L + ++ K L+ G V L Sbjct: 172 LKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLT-----GALEGSFVASFLLGW 226 Query: 476 AISAGLTT---PLDVVKTRLMTRVGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 I+ G +T PLD V+ R+M G + +++++ +EG L +G G + Sbjct: 227 VITMGASTASYPLDTVRRRMMMTSGQTIKYDGALDCLRKIVQKEGAYSLFKGCGANIFRG 286 Query: 308 ACFAAI 291 A + Sbjct: 287 VAAAGV 292 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 10/147 (6%) Frame = -3 Query: 647 DGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGALAGA 474 +G + G A +LR P L+++ + +K+ ++ G AG Sbjct: 71 EGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRERDGYAKWFAGNLFSGGAAGG 130 Query: 473 ISAGLTTPLDVVKTRLMTRVGAQGSRT--------VVGTMQEVIAEEGLMGLSRGIGPRV 318 +S LD +TRL A+GS++ ++ ++ + +GL+GL RG P V Sbjct: 131 LSLLFVYSLDYARTRLAA--DARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSV 188 Query: 317 LHSACFAAIGYCAFETARLMILKSYLE 237 L + + + +++ + ++L LE Sbjct: 189 LGIIVYRGLYFGLYDSFKPVLLTGALE 215
>ADT2_HUMAN (P05141) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) (ADP,ATP carrier protein, fibroblast isoform) Length = 297 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 488 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 336 LA +AG T+ PLD +TRL VG G+ R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQ 174 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMI 255 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 38.5 bits (88), Expect = 0.018 Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIVISW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 330 +A ++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ADT2_BOVIN (Q8SQH5) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 40.0 bits (92), Expect = 0.006 Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 488 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 336 LA +AG T+ PLD +TRL VG G+ R + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIRGLYQ 174 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMI 255 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 38.1 bits (87), Expect = 0.024 Identities = 32/125 (25%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 LVKIYKSDGIRGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 330 +A +++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGAKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ADT2_MAIZE (P12857) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 387 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/148 (21%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 142 IKDEGFSSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 201 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQ---GSRT---VVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 202 AGASSLFFVYSLDYARTRLANDAKAAKGGGDRQFNGLVDVYRKTLKSDGIAGLYRGFNIS 261 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLE 237 + + + + +++ + ++L L+ Sbjct: 262 CVGIIVYRGLYFGLYDSIKPVVLTGSLQ 289 Score = 39.3 bits (90), Expect = 0.011 Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L++DG GLY G+ + + + L + ++ +K L+ S N S G L Sbjct: 246 LKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGSLQDNFFA--SFALGWLI- 302 Query: 476 AISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AGL + P+D V+ R+M G A ++ + Q+++ +EG L +G G +L + Sbjct: 303 TNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGPKSLFKGAGANILRAIA 362 Query: 302 FAAI 291 A + Sbjct: 363 GAGV 366
>ADT1_MAIZE (P04709) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 387 Score = 39.7 bits (91), Expect = 0.008 Identities = 30/148 (20%), Positives = 62/148 (41%), Gaps = 8/148 (5%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 142 IKDEGFSSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 201 Query: 482 AGAISAGLTTPLDVVKTRLMTRV------GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LD +TRL G + +V ++ + +G+ GL RG Sbjct: 202 AGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 261 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLE 237 + + + + +++ + ++L L+ Sbjct: 262 CVGIIVYRGLYFGLYDSIKPVVLTGNLQ 289 Score = 38.1 bits (87), Expect = 0.024 Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 2/124 (1%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L++DG GLY G+ + + + L + ++ +K L+ + N S G L Sbjct: 246 LKSDGIAGLYRGFNISCVGIIVYRGLYFGLYDSIKPVVLTGNLQDNFFA--SFALGWLI- 302 Query: 476 AISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 AGL + P+D V+ R+M G A ++ + Q+++ +EG L +G G +L + Sbjct: 303 TNGAGLASYPIDTVRRRMMMTSGEAVKYKSSLDAFQQILKKEGPKSLFKGAGANILRAIA 362 Query: 302 FAAI 291 A + Sbjct: 363 GAGV 366
>ADT1_HUMAN (P12235) ADP/ATP translocase 1 (Adenine nucleotide translocator 1)| (ANT 1) (ADP,ATP carrier protein 1) (Solute carrier family 25 member 4) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) Length = 297 Score = 39.7 bits (91), Expect = 0.008 Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 13/151 (8%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 516 +++I + GF + G A ++R P L+++ + K L + A NL Sbjct: 57 VVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNL 116 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAE----EGLM 348 G + AGA S PLD +TRL VG ++ + + I + +GL Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLR 170 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 GL +G V + A + ++TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYDTAKGML 201 Score = 35.4 bits (80), Expect = 0.16 Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 IIKIFKSDGLRGLYQGFNVSV-----QGIIIYRA-AYFGVYDTAKGMLPDPKNVHIFVSW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV----VGTMQEVIAEEGLMGLSRGI 330 +A +++A GL + P D V+ R+M + G +G+ + V +++ +EG +G Sbjct: 214 MIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ADT1_ANOGA (Q27238) ADP,ATP carrier protein 1 (ADP/ATP translocase 1) (Adenine| nucleotide translocator 1) (ANT 1) Length = 301 Score = 39.7 bits (91), Expect = 0.008 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 8/145 (5%) Frame = -3 Query: 665 LQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVL--- 495 ++I + G + G A ++R P L+++ + K L + N L Sbjct: 61 VRIPKEQGIGAFWRGNLANVIRYFPTQALNFAFKDVYKQVFLGGVDK-NTQFWRYFLGNL 119 Query: 494 -CGALAGAISAGLTTPLDVVKTRLMTRVG-AQGSRTVVG---TMQEVIAEEGLMGLSRGI 330 G AGA S PLD +TRL VG G R G +++ + +G++GL RG Sbjct: 120 GSGGAAGATSLCFVYPLDFARTRLGADVGRGAGEREFNGLLDCLKKTVKSDGIIGLYRGF 179 Query: 329 GPRVLHSACFAAIGYCAFETARLMI 255 V + A + F+TA+ M+ Sbjct: 180 NVSVQGIIIYRAAYFGCFDTAKGML 204 Score = 30.8 bits (68), Expect = 3.8 Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L + +++DG GLY G+ ++ G++ Y + Y F +K P+ + Sbjct: 163 LKKTVKSDGIIGLYRGFNVSV-----QGIIIYRA-AYFGCFDTAKGMLPDPKNTSIFVSW 216 Query: 488 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGSRTV 390 A+A ++ ++ P D V+ R+M + G S + Sbjct: 217 AIAQVVTTASGIISYPFDTVRRRMMMQSGRAKSEVM 252
>ADT1_SOLTU (P25083) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) Length = 386 Score = 39.3 bits (90), Expect = 0.011 Identities = 30/148 (20%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 141 IKEEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 200 Query: 482 AGAISAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LD +TRL + G + +V ++ + +G+ GL RG Sbjct: 201 AGASSLFFVYSLDYARTRLANDRKASKKGGERQFNGLVDVYKKTLKSDGIAGLYRGFNIS 260 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLE 237 + + + + +++ + ++L L+ Sbjct: 261 CVGIIVYRGLYFGMYDSLKPVLLTGNLQ 288
>ADT_NEUCR (P02723) ADP,ATP carrier protein (ADP/ATP translocase) (Adenine| nucleotide translocator) (ANT) Length = 313 Score = 39.3 bits (90), Expect = 0.011 Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 8/130 (6%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE---SVLCGA 486 + +DG GLY G+ ++ AG++ Y F L S P L G+ + L Sbjct: 172 IASDGIAGLYRGFGPSV-----AGIVVYRGLY----FGLYDSIKPVLLVGDLKNNFLASF 222 Query: 485 LAG---AISAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 G +AG+ + PLD ++ R+M G A ++ +++A+EG+ L +G G Sbjct: 223 ALGWCVTTAAGIASYPLDTIRRRMMMTSGEAVKYKSSFDAASQIVAKEGVKSLFKGAGAN 282 Query: 320 VLHSACFAAI 291 +L A + Sbjct: 283 ILRGVAGAGV 292
>DIC1_CANGA (Q6FTN2) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) Length = 295 Score = 38.9 bits (89), Expect = 0.014 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 2/66 (3%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNL--TPGESVL 495 L IL+ +G GLYAG +A+LLR + ++ LK + + N+ G S++ Sbjct: 48 LRSILKNEGIVGLYAGLSASLLRQCTYTTARFGMYDALKEHVIPRDKLTNMWYLLGASMV 107 Query: 494 CGALAG 477 GAL G Sbjct: 108 SGALGG 113 Score = 36.2 bits (82), Expect = 0.092 Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 3/135 (2%) Frame = -3 Query: 668 LLQILQTDGFFGLY-AGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLC 492 +++I + +G L+ G+ ++R + +++ K F ++K N + Sbjct: 147 MVKIYKAEGAKSLFLTGWKPNMVRGVLMTASQVVTYDMFKNFLVTKYNMDPKKNSTHLTS 206 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 318 LAG ++ + +P DV+KT +M G + + E I +EG + RG P Sbjct: 207 SLLAGFVATTVCSPADVIKTIVMNAHKKPGHNHDSSFKILMEAINKEGPSFMFRGWVPSF 266 Query: 317 LHSACFAAIGYCAFE 273 A F + + A E Sbjct: 267 TRLAPFTMLIFFAME 281 Score = 34.7 bits (78), Expect = 0.27 Identities = 22/76 (28%), Positives = 35/76 (46%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 G AG + T PLD+ K RL + T+V ++ ++ EG++GL G+ +L Sbjct: 13 GGAAGIFAVMNTHPLDLTKVRL--QAAPIPKPTIVQMLRSILKNEGIVGLYAGLSASLLR 70 Query: 311 SACFAAIGYCAFETAR 264 C + TAR Sbjct: 71 Q--------CTYTTAR 78
>YG2O_YEAST (P53257) Putative mitochondrial carrier YGR096W| Length = 314 Score = 38.9 bits (89), Expect = 0.014 Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 4/160 (2%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFE----YLKAFALSKSNAPNLTPGESVLC 492 +++ +G + G L + G +SS+ YL F L S++ Sbjct: 66 MIKNEGIRSFWKGNIPGSLLYVTYGSAQFSSYSLFNRYLTPFGLEARL-------HSLVV 118 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 GA AG S+ ++ P DV++TRL+ S ++ ++++ EGL G +G + Sbjct: 119 GAFAGITSSIVSYPFDVLRTRLVAN-NQMHSMSITREVRDIWKLEGLPGFFKGSIASMTT 177 Query: 311 SACFAAIGYCAFETARLMILKSYLESCERKAADEMKTGVA 192 A+I + +ET R+ Y + E+ A K +A Sbjct: 178 ITLTASIMFGTYETIRI-----YCDENEKTTAAHKKWELA 212
>ADT2_RAT (Q09073) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 38.9 bits (89), Expect = 0.014 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 488 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 336 LA +AG T+ PLD +TRL VG G+ + + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQ 174 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMI 255 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 37.0 bits (84), Expect = 0.054 Identities = 32/125 (25%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 330 +A +++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>ADT2_MOUSE (P51881) ADP/ATP translocase 2 (Adenine nucleotide translocator 2)| (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) Length = 297 Score = 38.9 bits (89), Expect = 0.014 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 9/147 (6%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 +++I + G + G A ++R P L+++ + K L T G Sbjct: 57 VVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG--GVDKRTQFWRYFAG 114 Query: 488 ALAGAISAGLTT-----PLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLMGLSR 336 LA +AG T+ PLD +TRL VG G+ + + + ++ +G+ GL + Sbjct: 115 NLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFKGLGDCLVKIYKSDGIKGLYQ 174 Query: 335 GIGPRVLHSACFAAIGYCAFETARLMI 255 G V + A + ++TA+ M+ Sbjct: 175 GFNVSVQGIIIYRAAYFGIYDTAKGML 201 Score = 37.7 bits (86), Expect = 0.031 Identities = 32/125 (25%), Positives = 63/125 (50%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ + Sbjct: 160 LVKIYKSDGIKGLYQGFNVSV-----QGIIIYRA-AYFGIYDTAKGMLPDPKNTHIFISW 213 Query: 488 ALAGAISA--GLTT-PLDVVKTRLMTRVGAQGSRTV-VGTM---QEVIAEEGLMGLSRGI 330 +A +++A GLT+ P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQSVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGSKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278
>M2OM_RAT (P97700) Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)| (Solute carrier family 25 member 11) Length = 313 Score = 38.5 bits (88), Expect = 0.018 Identities = 39/149 (26%), Positives = 58/149 (38%), Gaps = 8/149 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPG--ESVL 495 L IL+ +G G+Y G +A LLR + L P PG L Sbjct: 67 LTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTP---PGFLLKAL 123 Query: 494 CGALAGAISAGLTTPLDVVKTRLMTRVG------AQGSRTVVGTMQEVIAEEGLMGLSRG 333 G AGA A + P +V R MT G +G + V + + EEG+ L RG Sbjct: 124 IGMTAGATGAFVGPPAEVALIR-MTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWRG 182 Query: 332 IGPRVLHSACFAAIGYCAFETARLMILKS 246 P + + A ++ ++ +L S Sbjct: 183 CIPTMARAVVVNAAQLASYSQSKQFLLDS 211 Score = 35.4 bits (80), Expect = 0.16 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 7/122 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I + +G L+ G T+ R + +S+ K F L +++LC Sbjct: 167 LIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYF-----SDNILCH 221 Query: 488 ALAGAISAGLTT----PLDVVKTRL--MTRVGAQGS-RTVVGTMQEVIAEEGLMGLSRGI 330 A IS +TT P+D+VKTR+ M + + + + + +V+ EG L +G Sbjct: 222 FCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKPEYKNGLDVLLKVVRYEGFFSLWKGF 281 Query: 329 GP 324 P Sbjct: 282 TP 283 Score = 29.6 bits (65), Expect = 8.6 Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Frame = -3 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS-----RTVVGTMQEVIAEEGLMGLSRG 333 L G LAG + PLD+V R+ ++ +G+ +T + ++ EGL G+ G Sbjct: 25 LFGGLAGMGATVFVQPLDLVXNRM--QLSGEGAKTREYKTSFHALTSILKAEGLRGIYTG 82 Query: 332 IGPRVLHSACF 300 + +L A + Sbjct: 83 LSAGLLRQATY 93
>UCP1_MOUSE (P12242) Mitochondrial brown fat uncoupling protein 1 (UCP 1)| (Thermogenin) Length = 306 Score = 38.1 bits (87), Expect = 0.024 Identities = 31/138 (22%), Positives = 58/138 (42%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALA 480 I T+ L+ G L+RN+ +++ +K ++ + P +L +A Sbjct: 163 IATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVNNKILADDVPCH-LLSALVA 221 Query: 479 GAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACF 300 G + L +P+DVVKTR + + Q +V + +EG +G L + Sbjct: 222 GFCTTLLASPVDVVKTRFINSLPGQ-YPSVPSCAMSMYTKEGPTAFFKGFVASFLRLGSW 280 Query: 299 AAIGYCAFETARLMILKS 246 I + FE + ++KS Sbjct: 281 NVIMFVCFEQLKKELMKS 298
>ADT1_GOSHI (O22342) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 386 Score = 38.1 bits (87), Expect = 0.024 Identities = 29/148 (19%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 141 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 200 Query: 482 AGAISAGLTTPLDVVKTRLMT------RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 AGA S LD +TRL + G + +V ++ + +G+ GL RG Sbjct: 201 AGASSLLFVYSLDYARTRLANDAKAAKKGGERQFNGLVDVYRKTLKSDGIAGLYRGFNIS 260 Query: 320 VLHSACFAAIGYCAFETARLMILKSYLE 237 + + + + +++ + ++L ++ Sbjct: 261 CVGIIVYRGLYFGMYDSLKPVLLTGSMQ 288
>ADT2_ARATH (P40941) ADP,ATP carrier protein 2, mitochondrial precursor| (ADP/ATP translocase 2) (Adenine nucleotide translocator 2) (ANT 2) Length = 385 Score = 37.7 bits (86), Expect = 0.031 Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 8/130 (6%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGE---SVLCGA 486 L++DG GLY G+ + AG++ Y F L S P L G+ S Sbjct: 244 LKSDGIAGLYRGFNISC-----AGIIVYRGLY----FGLYDSVKPVLLTGDLQDSFFASF 294 Query: 485 LAGAI---SAGLTT-PLDVVKTRLMTRVG-AQGSRTVVGTMQEVIAEEGLMGLSRGIGPR 321 G + AGL + P+D V+ R+M G A ++ +++ +EG L +G G Sbjct: 295 ALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSFDAFSQIVKKEGAKSLFKGAGAN 354 Query: 320 VLHSACFAAI 291 +L + A + Sbjct: 355 ILRAVAGAGV 364
>ADT1_ARATH (P31167) ADP,ATP carrier protein 1, mitochondrial precursor| (ADP/ATP translocase 1) (Adenine nucleotide translocator 1) (ANT 1) Length = 381 Score = 37.7 bits (86), Expect = 0.031 Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 135 IKDEGFGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGA 194 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQ----GSRT---VVGTMQEVIAEEGLMGLSRGIGP 324 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 195 AGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQFDGLVDVYRKTLKTDGIAGLYRGFNI 254 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYLE 237 + + + + +++ + ++L L+ Sbjct: 255 SCVGIIVYRGLYFGLYDSVKPVLLTGDLQ 283
>MFN2B_XENLA (Q68F18) Mitoferrin-2B (Mitochondrial iron transporter 2-B) (Solute| carrier family 25 member 28-B) Length = 186 Score = 37.7 bits (86), Expect = 0.031 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 17/113 (15%) Frame = -3 Query: 587 GVLSYSSFEYLKAFALSKSNAPN---LTPGESV----LCGALAGAISAGLTTPLDVVKTR 429 G L++ S + L+ N P L G +V L GA+AG + L P+D VKTR Sbjct: 45 GTLAFESTSSSRILELTSDNDPEYEALPEGSNVTAHMLAGAVAGVMEHCLMYPVDCVKTR 104 Query: 428 LMTRV--GAQGSRTVVGTMQEVIAEEG----LMGL---SRGIGP-RVLHSACF 300 + + A R V+ + +++ EG L GL + G GP L+ AC+ Sbjct: 105 MQSLQPDPAARYRNVMDALSKIVRTEGFWRPLRGLNVTATGAGPAHALYFACY 157
>ADT2_SOLTU (P27081) ADP,ATP carrier protein, mitochondrial precursor (ADP/ATP| translocase) (Adenine nucleotide translocator) (ANT) (Fragment) Length = 386 Score = 37.4 bits (85), Expect = 0.041 Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTP--GESVLCGAL 483 ++ +GF L+ G A ++R P L+++ +Y K K + ++ G Sbjct: 140 IKDEGFAALWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDRDGYWKWFAGNLASGGG 199 Query: 482 AGAISAGLTTPLDVVKTRLMTRVGAQ----GSRT---VVGTMQEVIAEEGLMGLSRGIGP 324 AGA S LD +TRL A G R +V ++ + +G+ GL RG Sbjct: 200 AGASSLLFVYSLDYARTRLANDAKAAKKGGGGRQFDGLVDVYRKTLKSDGVAGLYRGFNI 259 Query: 323 RVLHSACFAAIGYCAFETARLMILKSYLE 237 + + + + +++ + ++L +E Sbjct: 260 SCVGIIVYRGLYFGMYDSLKPVLLTGKME 288
>DIC1_YEAST (Q06143) Mitochondrial dicarboxylate transporter (Dicarboxylate| carrier 1) (DTP) Length = 298 Score = 36.2 bits (82), Expect = 0.092 Identities = 25/124 (20%), Positives = 54/124 (43%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAGAISA 465 G L+ G+ ++R + +++ K + ++K + + LAG ++ Sbjct: 163 GLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKNYTHLTASLLAGLVAT 222 Query: 464 GLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGY 285 + +P DV+KTR+M G+ + + + + + +EG + RG P F + + Sbjct: 223 TVCSPADVMKTRIMN--GSGDHQPALKILADAVRKEGPSFMFRGWLPSFTRLGPFTMLIF 280 Query: 284 CAFE 273 A E Sbjct: 281 FAIE 284
>PIC2_YEAST (P40035) Mitochondrial phosphate carrier protein 2 (Phosphate| transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2) Length = 300 Score = 35.8 bits (81), Expect = 0.12 Identities = 29/132 (21%), Positives = 54/132 (40%), Gaps = 2/132 (1%) Frame = -3 Query: 662 QILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESV--LCG 489 +I+ +G+ +Y G+ AT + G Y +EY K S L+PG +V + Sbjct: 62 KIIANEGWKKVYTGFGATFVGYSLQGAGKYGGYEYFKHLYSSW-----LSPGVTVYLMAS 116 Query: 488 ALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHS 309 A A ++ + P + +K + T + + V G + G+ +GI P Sbjct: 117 ATAEFLADIMLCPFEAIKVKQQTTMPPFCNNVVDGWKKMYAESGGMKAFYKGIVPLWCRQ 176 Query: 308 ACFAAIGYCAFE 273 + + +FE Sbjct: 177 IPYTMCKFTSFE 188 Score = 33.1 bits (74), Expect = 0.78 Identities = 25/139 (17%), Positives = 61/139 (43%), Gaps = 6/139 (4%) Frame = -3 Query: 653 QTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYL--KAFALSKSNAPNLTPGESV----LC 492 ++ G Y G R +P + ++SFE + K +++ + + + + Sbjct: 158 ESGGMKAFYKGIVPLWCRQIPYTMCKFTSFEKIVQKIYSVLPKKKEEMNALQQISVSFVG 217 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLH 312 G LAG + A ++ P DV+ +++ + A S +V + + + G GL G+ R++ Sbjct: 218 GYLAGILCAAVSHPADVMVSKINSERKANESMSVAS--KRIYQKIGFTGLWNGLMVRIVM 275 Query: 311 SACFAAIGYCAFETARLMI 255 + + +++ + + Sbjct: 276 IGTLTSFQWLIYDSFKAYV 294
>ADT3_PIG (Q6QRN9) ADP/ATP translocase 3 (Adenine nucleotide translocator 2)| (ANT 3) (ADP,ATP carrier protein 3) (Solute carrier family 25 member 6) Length = 297 Score = 35.8 bits (81), Expect = 0.12 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 7/125 (5%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCG 489 L++I ++DG GLY G+ ++ G++ Y + Y + +K P+ V+ Sbjct: 160 LVKITKSDGIRGLYQGFNVSV-----QGIIIYRA-AYFGVYGTAKGMLPDPRNTHIVVSW 213 Query: 488 ALAGAISAG---LTTPLDVVKTRLMTRVGAQGSRTVV-GTM---QEVIAEEGLMGLSRGI 330 +A ++A + P D V+ R+M + G +G+ + GT+ +++ +EG +G Sbjct: 214 MIAQTVTAVAGVFSYPFDTVRRRMMMQSGRKGADIMYKGTLDCWRKIFKDEGGKAFFKGA 273 Query: 329 GPRVL 315 VL Sbjct: 274 WSNVL 278 Score = 35.8 bits (81), Expect = 0.12 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 13/151 (8%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSN---------APNL 516 +++I + G + G A ++R P L+++ + K L + A NL Sbjct: 57 IVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNL 116 Query: 515 TPGESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS----RTVVGTMQEVIAEEGLM 348 G + AGA S PLD +TRL VG + + + + ++ +G+ Sbjct: 117 ASGGA------AGATSLCFVYPLDFARTRLAADVGKSATEREFKGLGDCLVKITKSDGIR 170 Query: 347 GLSRGIGPRVLHSACFAAIGYCAFETARLMI 255 GL +G V + A + + TA+ M+ Sbjct: 171 GLYQGFNVSVQGIIIYRAAYFGVYGTAKGML 201
>MFN2A_XENLA (Q6GLJ0) Mitoferrin-2A (Mitochondrial iron transporter 2-A) (Solute| carrier family 25 member 28-A) Length = 186 Score = 35.4 bits (80), Expect = 0.16 Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 17/113 (15%) Frame = -3 Query: 587 GVLSYSSFEYLKAFALSKSNAPN---LTPGESV----LCGALAGAISAGLTTPLDVVKTR 429 G L++ S SK N P L G +V L GA+AG + L P+D VKTR Sbjct: 45 GPLAFESTSSRILELASKDNEPEYEALPDGSNVTTHMLAGAVAGVMEHCLMYPVDCVKTR 104 Query: 428 LMTRV--GAQGSRTVVGTMQEVIAEEG----LMGL---SRGIGP-RVLHSACF 300 + + A R V+ + +++ EG L GL + G GP L+ AC+ Sbjct: 105 MQSLQPDPAARYRNVMDALSKIVRTEGFWRPLRGLNVTATGAGPAHALYFACY 157
>CMC1_YEAST (P48233) Calcium-binding mitochondrial carrier SAL1 (Suppressor of| AAC2 lethality) Length = 545 Score = 35.4 bits (80), Expect = 0.16 Identities = 27/133 (20%), Positives = 53/133 (39%), Gaps = 6/133 (4%) Frame = -3 Query: 644 GFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKS---NAPNLTPGESVLCGALAGA 474 G Y G +++ P + + SFE K + +L+ + + G LAG Sbjct: 300 GIKAFYVGNGLNVIKVFPESSIKFGSFEVTKKIMTKLEGCRDTKDLSKFSTYIAGGLAGM 359 Query: 473 ISAGLTTPLDVVKTRLMTR---VGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSAC 303 + P+D +K R+ +G+ + T +++ E GL RG+ ++ Sbjct: 360 AAQFSVYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGLRLFYRGVTVGIVGIFP 419 Query: 302 FAAIGYCAFETAR 264 +AA+ F + Sbjct: 420 YAALDLGTFSALK 432 Score = 35.0 bits (79), Expect = 0.20 Identities = 17/41 (41%), Positives = 25/41 (60%) Frame = -3 Query: 668 LLQILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAF 546 LL+ L+ +G+ GL+ G TL + PA +SY +E LK F Sbjct: 501 LLKTLEREGYQGLFKGLVPTLAKVCPAVSISYLCYENLKKF 541
>MCAR1_HUMAN (Q9H1U9) Mitochondrial carrier triple repeat 1| Length = 297 Score = 35.0 bits (79), Expect = 0.20 Identities = 24/84 (28%), Positives = 39/84 (46%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L+ G Y G L RN + VL + +K L + + +CG L G Sbjct: 164 LKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEH-LPTATTHSAHLVNDFICGGLLG 222 Query: 476 AISAGLTTPLDVVKTRLMTRVGAQ 405 A+ L P++VVKTR+ +++G + Sbjct: 223 AMLGFLFFPINVVKTRIQSQIGGE 246 Score = 31.6 bits (70), Expect = 2.3 Identities = 24/77 (31%), Positives = 34/77 (44%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L+ DGF LY G L++ L + +E L +AP S + LAG Sbjct: 72 LRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEF--ATSGVAAVLAG 129 Query: 476 AISAGLTTPLDVVKTRL 426 A + TPL+ V+T L Sbjct: 130 TTEA-IFTPLERVQTLL 145
>YHM2_YEAST (Q04013) Mitochondrial DNA replication protein YHM2| Length = 314 Score = 34.7 bits (78), Expect = 0.27 Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 3/70 (4%) Frame = -3 Query: 518 LTPGESVLCGALAGAISAGLTTPLDVVKTRLMTRV---GAQGSRTVVGTMQEVIAEEGLM 348 L P E + AL G +SA P++V++ + ++ + TV T + + GL Sbjct: 213 LNPFEKIGASALGGGLSAW-NQPIEVIRVEMQSKKEDPNRPKNLTVGKTFKYIYQSNGLK 271 Query: 347 GLSRGIGPRV 318 GL RG+ PR+ Sbjct: 272 GLYRGVTPRI 281
>MTCH1_MOUSE (Q791T5) Mitochondrial carrier homolog 1 (Mitochondrial| carrier-like protein 1) Length = 389 Score = 34.7 bits (78), Expect = 0.27 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 8/128 (6%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPG-----ESV 498 I+Q DG GL+ G + L+ N + V S + + + SN ++ + Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTSLKKVVKET 198 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGP 324 + +S L PL V+ R M + VG + + V+ ++ ++ EEGL+G G+ P Sbjct: 199 SYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIP 258 Query: 323 RVLHSACF 300 +L F Sbjct: 259 HLLGDVVF 266
>MTCH1_HUMAN (Q9NZJ7) Mitochondrial carrier homolog 1 (Presenilin-associated| protein) Length = 389 Score = 34.7 bits (78), Expect = 0.27 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 8/128 (6%) Frame = -3 Query: 659 ILQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSK-SNAPNLTPG-----ESV 498 I+Q DG GL+ G + L+ N + V S + + + SN ++ + Sbjct: 139 IVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKET 198 Query: 497 LCGALAGAISAGLTTPLDVVKTRLMTR-VGAQGSRT-VVGTMQEVIAEEGLMGLSRGIGP 324 + +S L PL V+ R M + VG + + V+ ++ ++ EEGL+G G+ P Sbjct: 199 SYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIP 258 Query: 323 RVLHSACF 300 +L F Sbjct: 259 HLLGDVVF 266
>ANT1_YEAST (Q06497) Peroxisomal adenine nucleotide transporter 1| Length = 328 Score = 34.3 bits (77), Expect = 0.35 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 14/73 (19%) Frame = -3 Query: 506 ESVLCGALAGAISAGLTTPLDVVKTRLMTRVGAQGS--------------RTVVGTMQEV 369 ES L GA+A A++ PLD+ KT + ++V S + VV M + Sbjct: 5 ESALTGAVASAMANIAVYPLDLSKTIIQSQVSPSSSEDSNEGKVLPNRRYKNVVDCMINI 64 Query: 368 IAEEGLMGLSRGI 330 E+G++GL +G+ Sbjct: 65 FKEKGILGLYQGM 77
>MPCP_CHOFU (O61703) Phosphate carrier protein, mitochondrial precursor| (Phosphate transport protein) (PTP) Length = 349 Score = 34.3 bits (77), Expect = 0.35 Identities = 25/124 (20%), Positives = 57/124 (45%), Gaps = 8/124 (6%) Frame = -3 Query: 602 RNLPAGVLSYSSFE----YLKAFALSKSNAPNLTPGESVL----CGALAGAISAGLTTPL 447 R +P ++ ++ FE L + K A + GE ++ G +AG A ++ P Sbjct: 211 RQIPYTMMKFACFEKTVELLYKHVVPKPRA-ECSKGEQLVVTFAAGYIAGVFCAIVSHPA 269 Query: 446 DVVKTRLMTRVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGYCAFETA 267 D V ++L ++ T+ ++ + G G+ +G+GPR++ A+ + ++ Sbjct: 270 DTVVSKL--------NQDKTATVGSIVGKLGFAGVWKGLGPRIIMIGTLTALQWFIYDAV 321 Query: 266 RLMI 255 ++ + Sbjct: 322 KVWL 325
>MCAR1_MOUSE (Q5HZI9) Mitochondrial carrier triple repeat 1| Length = 298 Score = 33.1 bits (74), Expect = 0.78 Identities = 22/82 (26%), Positives = 38/82 (46%) Frame = -3 Query: 656 LQTDGFFGLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPNLTPGESVLCGALAG 477 L+ G Y G L RN VL + +K +L + + +CG + G Sbjct: 165 LRCHGIAEYYRGMVPILFRNGFGNVLFFGLRGPIKE-SLPTATTYSAHLVNDFICGGVLG 223 Query: 476 AISAGLTTPLDVVKTRLMTRVG 411 A+ L+ P++VVK R+ +++G Sbjct: 224 AVLGFLSFPINVVKARIQSQIG 245
>YMC2_YEAST (P38087) Carrier protein YMC2, mitochondrial precursor| Length = 329 Score = 32.0 bits (71), Expect = 1.7 Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 3/124 (2%) Frame = -3 Query: 635 GLYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNAPN-LTPGESVLCGALAGAISAGL 459 GL G T++R + +E L A + N + P + L GA +G + Sbjct: 197 GLMRGLFPTMIRAGHGLGTYFLVYEALVAREIGTGLTRNEIPPWKLCLFGAFSGTMLWLT 256 Query: 458 TTPLDVVKTRLMTRV--GAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIGY 285 PLDVVK+ + + ++ + + A+EG+ +G GP ++ SA + Sbjct: 257 VYPLDVVKSIIQNDDLRKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGATF 316 Query: 284 CAFE 273 FE Sbjct: 317 LTFE 320
>VE4_HPV05 (P06924) Probable protein E4| Length = 245 Score = 32.0 bits (71), Expect = 1.7 Identities = 23/74 (31%), Positives = 28/74 (37%), Gaps = 7/74 (9%) Frame = +3 Query: 309 AVQDPRSDPPGQAH---QAFLGDDLLHRAHDRAAPLGAHPGHQPRLDDVE----RGGEPR 467 A +DP P A + G D H AP H GH+P++ E R G Sbjct: 121 ADRDPEEGPQPPAEGEVEGHPGGDQGHPPPPPPAPHNGHSGHEPKVQQPEGPEGREGHEE 180 Query: 468 GYRAGEGAAEHALP 509 G GEG E P Sbjct: 181 GAVGGEGGDEEGHP 194
>MFRN1_BOVIN (Q3ZBJ8) Mitoferrin-1 (Mitochondrial iron transporter 1) (Solute| carrier family 25 member 37) Length = 171 Score = 31.6 bits (70), Expect = 2.3 Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Frame = -3 Query: 491 GALAGAISAGLTTPLDVVKTRLMTRVGAQGSR--TVVGTMQEVIAEEGLMGLSRGIGPRV 318 GA+AG + + P+D VKTR+ + + +V G ++++I EG RG+ + Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQSLNPDPKAHYTSVYGALKKIIRTEGFWRPLRGLNVMM 111 Query: 317 LHSACFAAIGYCAFETAR 264 + + A+ + +E + Sbjct: 112 MGAGPAHAMYFACYENMK 129
>YMC1_YEAST (P32331) Carrier protein YMC1, mitochondrial precursor| Length = 307 Score = 31.2 bits (69), Expect = 2.9 Identities = 29/131 (22%), Positives = 55/131 (41%), Gaps = 5/131 (3%) Frame = -3 Query: 632 LYAGYAATLLRNLPAGVLSYSSFEYLKAFALSKSNA---PNLTPGESVLCGALAGAISAG 462 L G T+LR + +E L A ++K ++ + + GAL+G Sbjct: 176 LLRGLTPTILREGHGCGTYFLVYEALIANQMNKRRGLERKDIPAWKLCIFGALSGTALWL 235 Query: 461 LTTPLDVVKTRLMT--RVGAQGSRTVVGTMQEVIAEEGLMGLSRGIGPRVLHSACFAAIG 288 + PLDV+K+ + T + ++ + + A G+ +G GP +L +A Sbjct: 236 MVYPLDVIKSVMQTDNLQKPKFGNSISSVAKTLYANGGIGAFFKGFGPTMLRAAPANGAT 295 Query: 287 YCAFETARLMI 255 + FE A ++ Sbjct: 296 FATFELAMRLL 306
>TOP1_TREPA (O83409) DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)| (Omega-protein) (Relaxing enzyme) (Untwisting enzyme) (Swivelase) Length = 731 Score = 30.0 bits (66), Expect = 6.6 Identities = 16/41 (39%), Positives = 19/41 (46%) Frame = -2 Query: 237 IVRKESRGRDEDRSCRCLSVCDSFPSFRKVIACSG*CAVFL 115 IV K++RGR E C VCD F+ A C FL Sbjct: 637 IVGKKTRGRKEFYGCTRFPVCDFVTHFKPTFAVCPQCRCFL 677
>MRSD_BACSY (Q9RC23) Mersacidin decarboxylase (EC 4.1.1.-)| (Mersacidin-modifying enzyme mrsD) Length = 194 Score = 30.0 bits (66), Expect = 6.6 Identities = 13/38 (34%), Positives = 18/38 (47%) Frame = +1 Query: 85 HLHNTIARWLQENCTLPRTSDYLPERRKGIAHTQAAAT 198 H H I RW C +P T++ L + G+A A T Sbjct: 73 HSHVEIGRWADIYCIIPATANILGQTANGVAMNLVATT 110
>MTG8_MOUSE (Q61909) Protein CBFA2T1 (MTG8 protein)| Length = 577 Score = 29.6 bits (65), Expect = 8.6 Identities = 16/33 (48%), Positives = 20/33 (60%) Frame = +1 Query: 415 TLVISRVLTTSSGVVSPADIAPARAPQSTLSPG 513 T +S +T SSG SP D PA P+ST +PG Sbjct: 536 TPAVSSSVTPSSGAGSPMDTPPAATPRST-TPG 567
>MUCDL_HUMAN (Q9HBB8) Mucin and cadherin-like protein precursor| (Mu-protocadherin) Length = 845 Score = 29.6 bits (65), Expect = 8.6 Identities = 23/74 (31%), Positives = 31/74 (41%) Frame = +3 Query: 243 VRLEDHEPGRLKCAVANRSEACAVQDPRSDPPGQAHQAFLGDDLLHRAHDRAAPLGAHPG 422 V + H RLKC C+ + P P G +QAFL D H+A+ P P Sbjct: 688 VLVHKHYGPRLKC--------CSGKAPEPQPQGFDNQAFLPD---HKANWAPVP---SPT 733 Query: 423 HQPRLDDVERGGEP 464 H P+ + EP Sbjct: 734 HDPKPAEAPMPAEP 747
>FTSK_PSEPK (Q88FS8) DNA translocase ftsK| Length = 834 Score = 29.6 bits (65), Expect = 8.6 Identities = 19/59 (32%), Positives = 27/59 (45%) Frame = +3 Query: 321 PRSDPPGQAHQAFLGDDLLHRAHDRAAPLGAHPGHQPRLDDVERGGEPRGYRAGEGAAE 497 P + P + H AF+ DD +HR + GA + L+ VE G G+ G G E Sbjct: 707 PGTSLPIRVHGAFVSDDEVHRTVEAWKLRGAPDYNDDILNGVEEAGS--GFDGGGGGGE 763 Database: uniprot_sprot.fasta Posted date: May 25, 2006 5:36 PM Number of letters in database: 80,573,946 Number of sequences in database: 219,361 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 68,538,230 Number of Sequences: 219361 Number of extensions: 1312555 Number of successful extensions: 4785 Number of sequences better than 10.0: 181 Number of HSP's better than 10.0 without gapping: 4274 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4635 length of database: 80,573,946 effective HSP length: 108 effective length of database: 56,882,958 effective search space used: 6484657212 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)
